locus-tag class description VEGS12_00010 ENOG4105VZ1 Replication Protein VEGS12_00050 ENOG4105ED4 portal protein VEGS12_00240 ENOG4108US3 tail fiber assembly VEGS12_00250 ENOG4105PTU response to oxidative stress VEGS12_00270 ENOG4108C33 Resolvase VEGS12_00360 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein VEGS12_00390 ENOG4105EBK exported protein VEGS12_00400 ENOG4108VTS Membrane VEGS12_00410 ENOG41065TG regulatoR VEGS12_00430 ENOG4105DP0 ferredoxin-NADP reductase VEGS12_00440 ENOG4105CBT Fructose-1,6-bisphosphatase VEGS12_00460 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) VEGS12_00470 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) VEGS12_00490 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase VEGS12_00520 ENOG41063M6 Cell Division Protein VEGS12_00530 ENOG4105ETE Transcriptional regulator (LacI family VEGS12_00540 ENOG4105C25 Primosomal protein n' VEGS12_00560 ENOG4105CNA YD repeat protein VEGS12_00600 ENOG4107S01 Repressor protein MetJ VEGS12_00620 ENOG4105C28 cystathionine VEGS12_00630 ENOG4105CFH Aspartokinase VEGS12_00640 ENOG4105SYT Methylenetetrahydrofolate reductase VEGS12_00660 ENOG4108Q5Y Membrane VEGS12_00670 ENOG4108XC3 NADH ubiquinone oxidoreductase VEGS12_00680 ENOG4105DCT glycerol dehydrogenase VEGS12_00690 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) VEGS12_00700 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) VEGS12_00710 ENOG4105DM4 PTS System VEGS12_00720 ENOG4108YRF PTS System VEGS12_00740 ENOG4108AHH pyruvate formate lyase II activase VEGS12_00750 ENOG4108XCZ PTS System VEGS12_00760 ENOG4106R3P AraC family transcriptional regulator VEGS12_00770 ENOG4105DIJ Phosphoethanolamine transferase VEGS12_00800 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase VEGS12_00830 ENOG4105CXK mandelate racemase muconate lactonizing VEGS12_00840 ENOG4108I5G Major Facilitator superfamily VEGS12_00850 ENOG4105C5Q Transcriptional regulator VEGS12_00870 ENOG4105EJ2 Transcriptional regulator VEGS12_00880 ENOG4108Y73 Membrane VEGS12_00900 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) VEGS12_00930 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase VEGS12_00960 ENOG4105PM1 preprotein translocase subunit SecE VEGS12_00970 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) VEGS12_01040 ENOG410645W Thiamin biosynthesis protein ThiH VEGS12_01050 ENOG4105D41 biosynthesis protein thiH VEGS12_01070 ENOG4105WHD thiamine biosynthesis protein ThiS VEGS12_01080 ENOG4105D06 uba thif-type nad fad binding protein VEGS12_01150 ENOG4105R2J Conserved Protein VEGS12_01170 ENOG4108T8B Protein of unknown function (DUF1481) VEGS12_01180 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism VEGS12_01190 ENOG4105BZU Histidine kinase VEGS12_01200 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family VEGS12_01210 ENOG4105C12 Phosphoribosylglycinamide synthetase VEGS12_01230 ENOG4105K5X acetyltransferase VEGS12_01250 ENOG4107QP3 malate synthase g VEGS12_01260 ENOG4108I9X Isocitrate lyase VEGS12_01290 ENOG41069M3 Transcriptional regulator VEGS12_01300 ENOG4105C3R Methionine synthase VEGS12_01310 ENOG4105EAM Na Pi-cotransporter VEGS12_01330 ENOG4105FE9 pseudouridine synthase VEGS12_01340 ENOG4108ZR5 Conserved Protein VEGS12_01360 ENOG410756H nucleotidyltransferase VEGS12_01380 ENOG4108WZA zeta toxin VEGS12_01390 ENOG4105CFH Aspartokinase VEGS12_01420 ENOG4108MDC (LipO)protein VEGS12_01430 ENOG4108Q9C Periplasmic Protein VEGS12_01440 ENOG4105E3R (LipO)protein VEGS12_01460 ENOG4107QNK )-transporter VEGS12_01470 ENOG4105EG2 ABC transporter, permease VEGS12_01480 ENOG4105D56 permease protein VEGS12_01490 ENOG4107FKK extracellular solute-binding protein family 1 VEGS12_01500 ENOG4108IJ9 (ABC) transporter VEGS12_01520 ENOG4107W52 maltose operon periplasmic protein VEGS12_01600 ENOG41080IJ Diacylglycerol kinase VEGS12_01620 ENOG4107R73 Mate efflux family protein VEGS12_01630 ENOG4105VDW Csbd family VEGS12_01640 ENOG4105MYN Zinc uptake regulation protein VEGS12_01670 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) VEGS12_01680 ENOG4105P4Z Phage shock protein G VEGS12_01690 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein VEGS12_01700 ENOG4105CDU Replicative dna helicase VEGS12_01710 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) VEGS12_01720 ENOG4105CGF Aromatic amino acid aminotransferase VEGS12_01760 ENOG4105F0S class B acid phosphatase VEGS12_01770 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme VEGS12_01780 ENOG4105MSB protein, conserved in bacteria VEGS12_01790 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) VEGS12_01800 ENOG4108UUM single-stranded DNA-binding protein VEGS12_01810 ENOG4105PMV Membrane VEGS12_01820 ENOG4108M8H domain protein VEGS12_01830 ENOG4108W3Q Transcriptional regulator VEGS12_01840 ENOG4108Z4X TRANSCRIPTIONal VEGS12_01850 ENOG4105C7N Xanthine uracil vitamin C permease VEGS12_01860 ENOG4105EEQ Na H antiporter VEGS12_01890 ENOG41062QD Membrane VEGS12_01900 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) VEGS12_01920 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit VEGS12_01930 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein VEGS12_01940 ENOG4105DVI reductase, NrfD VEGS12_01950 ENOG4108QKW cytochrome c-type biogenesis protein VEGS12_01970 ENOG4108W0S formate-dependent nitrite reductase complex VEGS12_01980 ENOG4105CK2 sodium dicarboxylate symporter VEGS12_01990 ENOG41082ND Uncharacterized protein yjcO VEGS12_02010 ENOG4105ETP RND efflux system, outer membrane lipoprotein VEGS12_02020 ENOG4108MI0 Resistance protein VEGS12_02030 ENOG4105J12 Multidrug resistance protein mdtN VEGS12_02050 ENOG4105EUZ Beta-lactamase domain protein VEGS12_02060 ENOG4108YZG isomerase VEGS12_02080 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein VEGS12_02090 ENOG410849A acetyltransferase, (GNAT) family VEGS12_02100 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) VEGS12_02110 ENOG4105FD8 phosphonate metabolism protein PhnM VEGS12_02120 ENOG4105HRV phosphonate c-p lyase system protein phnl VEGS12_02130 ENOG4105ENV phosphonate C-P lyase system protein PhnK VEGS12_02140 ENOG4105FT8 Phosphonate metabolism VEGS12_02150 ENOG4105EKV Phosphonate metabolism protein VEGS12_02160 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH VEGS12_02170 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG VEGS12_02180 ENOG4107RJJ Transcriptional regulator VEGS12_02200 ENOG4105EHI Phosphonate ABC transporter, periplasmic VEGS12_02210 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase VEGS12_02220 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA VEGS12_02230 ENOG4108F5E vimentin VEGS12_02240 ENOG4108YIV VEGS12_02250 ENOG4105CSH Transporter VEGS12_02260 ENOG4105ECM Sensor protein basS pmrB VEGS12_02270 ENOG4105XJC Two component transcriptional regulator (Winged helix family VEGS12_02280 ENOG4105DIJ Phosphoethanolamine transferase VEGS12_02290 ENOG4105D5Q Arginine ornithine antiporter VEGS12_02300 ENOG4106ZGR Transcriptional regulator VEGS12_02310 ENOG4105CXN decarboxylase VEGS12_02320 ENOG4108K2B transcriptional regulator VEGS12_02330 ENOG4105F8D glycoside hydrolase family 4 VEGS12_02340 ENOG4105CT4 transporter VEGS12_02350 ENOG4108R5S membrane VEGS12_02360 ENOG4107GFK fumarate VEGS12_02370 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter VEGS12_02380 ENOG4108MRH transcriptional regulatory protein VEGS12_02390 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism VEGS12_02400 ENOG4105VR1 Pfam:DUF1271 VEGS12_02410 ENOG410830R acetyltransferase VEGS12_02440 ENOG4105CRK lysyL-tRNA synthetase VEGS12_02450 ENOG4105DUX Transporter VEGS12_02460 ENOG4105CXN decarboxylase VEGS12_02470 ENOG4105D5Q Arginine ornithine antiporter VEGS12_02480 ENOG4108M3R transcriptional activator CadC VEGS12_02490 ENOG4108SIC Transcriptional regulator VEGS12_02520 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter VEGS12_02530 ENOG4108IJ0 Aspartate ammonia-lyase VEGS12_02540 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 VEGS12_02550 ENOG4105DVH amino acid VEGS12_02580 ENOG4108ZVF (LipO)protein VEGS12_02600 ENOG4105MTB Uncharacterized protein YjeJ VEGS12_02610 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein VEGS12_02630 ENOG4106BSU Entericidin B VEGS12_02640 ENOG4105KPY Small multidrug resistance protein VEGS12_02650 ENOG4105QNF Outer membrane lipoprotein VEGS12_02660 ENOG41066YJ Beta-lactamase VEGS12_02690 ENOG4105E33 succinate dehydrogenase VEGS12_02700 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) VEGS12_02720 ENOG4107SC7 Inner membrane transporter yjeM VEGS12_02730 ENOG4105EGS Mechanosensitive ion channel VEGS12_02770 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) VEGS12_02780 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) VEGS12_02790 ENOG4105K8N protein family UPF0079, ATPase VEGS12_02800 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase VEGS12_02840 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) VEGS12_02850 ENOG4107QJR hflk protein VEGS12_02860 ENOG4105EPW hflc protein VEGS12_02900 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) VEGS12_02910 ENOG4105C2N RNA methyltransferase TrmH family group 3 VEGS12_02920 ENOG4105FUX Conserved Protein VEGS12_02930 ENOG4108P9J Phage shock protein A VEGS12_02940 ENOG4107VNS Protein of unknown function (DUF2491) VEGS12_02950 ENOG4105Z6B inner membrane protein yjfl VEGS12_02960 ENOG4108KXT Conserved Protein VEGS12_02970 ENOG4106032 Glutathionylspermidine synthase VEGS12_02980 ENOG4105CSU acyl-Coa dehydrogenase VEGS12_02990 ENOG4105S17 UPF0379 protein yjfN VEGS12_03000 ENOG4105WSB biofilm stress and motility protein A VEGS12_03010 ENOG4108MXZ Esterase VEGS12_03040 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC VEGS12_03100 ENOG4105KIT UPF0379 protein yjfY VEGS12_03130 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) VEGS12_03150 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit VEGS12_03160 ENOG4105CG6 trap dicarboxylate transporter dctm subunit VEGS12_03170 ENOG41069H7 transport system small permease component VEGS12_03180 ENOG4107S3R L-aspartate oxidase VEGS12_03190 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) VEGS12_03200 ENOG4105E39 Enoyl-CoA hydratase VEGS12_03220 ENOG4105CHR reductase VEGS12_03240 ENOG4105FHY Opacity-associated protein A VEGS12_03250 ENOG4108V1T peptidylprolyl cis-trans isomerase VEGS12_03260 ENOG4105C85 amino acid VEGS12_03280 ENOG4105DXC membrane VEGS12_03290 ENOG4105ECR NmrA family VEGS12_03300 ENOG4105KVH Transcriptional regulator VEGS12_03310 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic VEGS12_03320 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase VEGS12_03330 ENOG4108UUE Transcriptional regulator VEGS12_03340 ENOG41061GZ Protein of unknown function (DUF1107) VEGS12_03350 ENOG4105C37 (CBS) domain VEGS12_03380 ENOG4105CFU surface antigen VEGS12_03390 ENOG4105MA0 exported protein VEGS12_03400 ENOG4108ZHD aig2 family VEGS12_03410 ENOG41087RY SpoVT_AbrB VEGS12_03420 ENOG4105MZG transcriptional modulator of maze toxin, mazf VEGS12_03430 ENOG4105F0N pyrophosphate phospho-hydrolase VEGS12_03440 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator VEGS12_03450 ENOG4105C2J ABC transporter VEGS12_03460 ENOG4107R9N ABC transporter VEGS12_03470 ENOG41062B0 ABC transporter, permease VEGS12_03490 ENOG4105DFU Cell wall formation (By similarity) VEGS12_03510 ENOG4105CMS peptidase U62, modulator of DNA gyrase VEGS12_03530 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) VEGS12_03540 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase VEGS12_03550 ENOG4105CG3 alpha amylase, catalytic region VEGS12_03560 ENOG4105C5Y PTS System VEGS12_03570 ENOG4105D4X repressor VEGS12_03580 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic VEGS12_03600 ENOG4105KME endoribonuclease L-psp VEGS12_03630 ENOG4108UQ8 endoribonuclease L-psp VEGS12_03640 ENOG4105F6U Short-chain dehydrogenase reductase Sdr VEGS12_03650 ENOG4108XFH Transcriptional regulator VEGS12_03660 ENOG4105XEP YhcH YjgK YiaL family protein VEGS12_03710 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) VEGS12_03720 ENOG4108MJ3 acetyltransferase VEGS12_03730 ENOG4108M3P Membrane VEGS12_03740 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) VEGS12_03750 ENOG4105MYG DNA polymerase iii, chi subunit VEGS12_03770 ENOG4108M8S permease YjgP YjgQ family protein VEGS12_03780 ENOG4108K5H permease YjgP YjgQ family protein VEGS12_03790 ENOG4105D7A ATP-binding protein VEGS12_03950 ENOG4107RRE RNA-directed DNA polymerase VEGS12_04000 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria VEGS12_04010 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off VEGS12_04030 ENOG4108S54 Fimbrial protein VEGS12_04040 ENOG4108NAE Fimbrial chaperone protein VEGS12_04050 ENOG4105CW0 outer membrane usher protein VEGS12_04060 ENOG4108SQA Fimbrial VEGS12_04070 ENOG4108T65 Fimbrial VEGS12_04080 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin VEGS12_04090 ENOG4107EFN gluconate transport system permease 3 VEGS12_04110 ENOG4105DEI Mannitol dehydrogenase VEGS12_04120 ENOG4105C6F GntR Family Transcriptional Regulator VEGS12_04150 ENOG4107YNJ LysR family Transcriptional regulator VEGS12_04160 ENOG4105DYB Isoaspartyl dipeptidase VEGS12_04170 ENOG4108P2H Inner membrane protein YjiG VEGS12_04180 ENOG41074DU domain protein VEGS12_04200 ENOG4105CBP Major Facilitator VEGS12_04230 ENOG4105CIZ coA-substrate-specific enzyme activase VEGS12_04240 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase VEGS12_04250 ENOG4106BRA Membrane VEGS12_04260 ENOG41083G8 Multidrug resistance protein MdtM VEGS12_04280 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family VEGS12_04310 ENOG4105CKI cobalamin synthesis protein VEGS12_04320 ENOG4105VCD cytoplasmic protein VEGS12_04330 ENOG4105D22 carbon starvation protein VEGS12_04340 ENOG4107UWN reductase VEGS12_04350 ENOG4105EFA 4-hydroxyphenylacetate VEGS12_04410 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase VEGS12_04420 ENOG4105C26 Dehydrogenase VEGS12_04430 ENOG4105ERH Fumarylacetoacetate hydrolase VEGS12_04440 ENOG4108V8F Transcriptional regulator, MarR family VEGS12_04450 ENOG4105C8Q Methyl-accepting chemotaxis VEGS12_04460 ENOG4108I5G Major Facilitator superfamily VEGS12_04470 ENOG410617M Transcriptional regulator VEGS12_04480 ENOG4105CPQ Dehydrogenase VEGS12_04500 ENOG4105RI1 glycoprotein receptor VEGS12_04510 ENOG4106CVF DNA replication protein VEGS12_04540 ENOG4105DWK Membrane VEGS12_04550 ENOG4108N8T regulatoR VEGS12_04560 ENOG4108T94 DNA-binding transcriptional activator BglJ VEGS12_04570 ENOG4108819 ferric iron reductase VEGS12_04580 ENOG4105YBH Protein of unknown function (DUF1435) VEGS12_04600 ENOG4108WPU DNA polymerase III subunit psi VEGS12_04610 ENOG4105KEG ribosomal-protein-alanine acetyltransferase VEGS12_04620 ENOG4105PAD Hydrolase VEGS12_04640 ENOG4105K3G Periplasmic Protein VEGS12_04660 ENOG4108NRW Phospholipase, patatin family VEGS12_04670 ENOG4105EYA deoxyribonuclease VEGS12_04680 ENOG41076CZ activating enzyme VEGS12_04700 ENOG4105G0K glycine radical enzyme YjjI family VEGS12_04770 ENOG41062Z9 Membrane VEGS12_04780 ENOG4105EAC phosphoserine phosphatase VEGS12_04790 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) VEGS12_04800 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase VEGS12_04810 ENOG4105C5H ABC transporter VEGS12_04820 ENOG4107SC1 transglycosylase VEGS12_04840 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) VEGS12_04860 ENOG4105UEI Transcriptional Regulator AraC Family VEGS12_04870 ENOG4108RH0 Crea protein VEGS12_04880 ENOG4105E3W Two component transcriptional regulator (Winged helix family VEGS12_04890 ENOG4105EB3 Histidine kinase VEGS12_04900 ENOG4105CT7 inner membrane cred family protein VEGS12_04910 ENOG41065U4 response regulator VEGS12_04920 ENOG4106FVC RNA methyltransferase VEGS12_04930 ENOG4105CFH Aspartokinase VEGS12_04950 ENOG4105D98 threonine synthase VEGS12_04990 ENOG4105BZG amino acid carrier protein VEGS12_05000 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) VEGS12_05010 ENOG4108RIR Molybdenum cofactor biosynthesis protein VEGS12_05020 ENOG4106HK8 GPR1 FUN34 yaaH family protein VEGS12_05030 ENOG4108QUJ UPF0174 protein YaaW VEGS12_05090 ENOG41063Z6 transcriptional regulator, lysR family VEGS12_05110 ENOG4105CW0 outer membrane usher protein VEGS12_05140 ENOG4105DTN riboflavin biosynthesis protein ribF VEGS12_05150 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) VEGS12_05170 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase VEGS12_05190 ENOG4105DU0 nucleoside hydrolase VEGS12_05210 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain VEGS12_05220 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain VEGS12_05240 ENOG4108XNW Transcriptional activatory protein CaiF VEGS12_05260 ENOG4106YT9 Enoyl-CoA hydratase VEGS12_05330 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase VEGS12_05340 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein VEGS12_05350 ENOG4105C54 Major Facilitator superfamily VEGS12_05380 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) VEGS12_05430 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) VEGS12_05440 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) VEGS12_05450 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) VEGS12_05460 ENOG4105D3G Pseudouridine synthase VEGS12_05480 ENOG4105CQ2 DNA polymerase VEGS12_05490 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase VEGS12_05520 ENOG41063TF transcriptional regulator (AraC VEGS12_05530 ENOG4108KF1 Membrane VEGS12_05550 ENOG4106SMU thiamine transporter membrane protein VEGS12_05560 ENOG4105DP9 ABC transporter VEGS12_05600 ENOG4105S8Q sugar efflux transporter VEGS12_05630 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) VEGS12_05650 ENOG41064T2 transcriptional regulator, lysR family VEGS12_05660 ENOG4105C7K acetolactate synthase VEGS12_05670 ENOG4108ZP8 Acetolactate synthase small subunit VEGS12_05680 ENOG4107B7Y DNA-binding transcriptional regulator FruR VEGS12_05710 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) VEGS12_05720 ENOG4105CJN penicillin-binding protein VEGS12_05730 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) VEGS12_05740 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) VEGS12_05770 ENOG4105CNI cell division protein FtsW VEGS12_05800 ENOG4105CPF Cell wall formation (By similarity) VEGS12_05810 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) VEGS12_05820 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) VEGS12_05830 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) VEGS12_05850 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) VEGS12_05870 ENOG4105M6F mutator MutT protein VEGS12_05900 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) VEGS12_05920 ENOG4105D7Q type ii secretion system VEGS12_05930 ENOG4105D7Q type ii secretion system VEGS12_05940 ENOG4107QHF type ii secretion system protein e VEGS12_05950 ENOG4108ZUW Major pilin subunit VEGS12_05960 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase VEGS12_05970 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase VEGS12_05980 ENOG4106A72 regulatory protein AmpE VEGS12_05990 ENOG4105C85 amino acid VEGS12_06000 ENOG41073TP transcriptional regulator VEGS12_06010 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) VEGS12_06020 ENOG4107QSN dihydrolipoamide acetyltransferase VEGS12_06030 ENOG4107QN2 dihydrolipoyl dehydrogenase VEGS12_06040 ENOG4108NST exported protein VEGS12_06050 ENOG4107QIJ Aconitate hydratase 2 VEGS12_06090 ENOG4108ZRK uncharacterized protein yacC VEGS12_06100 ENOG4105E3B Multicopper oxidase VEGS12_06110 ENOG4105DZG Dehydrogenase VEGS12_06120 ENOG4108UGV hypoxanthine phosphoribosyltransferase VEGS12_06130 ENOG41077A9 carbonic anhydrase VEGS12_06140 ENOG4105DA5 (ABC) transporter VEGS12_06150 ENOG4105E3A (ABC) transporter VEGS12_06160 ENOG4108YTN IIa component VEGS12_06170 ENOG4107BJW polysaccharide deacetylase VEGS12_06190 ENOG4108A32 Transposase VEGS12_06220 ENOG4105P0Q fimbrial-like protein YadC VEGS12_06230 ENOG4105SN2 fimbrial-like adhesin protein VEGS12_06240 ENOG4105SN2 fimbrial-like adhesin protein VEGS12_06250 ENOG4105SYG Fimbrial protein VEGS12_06260 ENOG4108XEY fimbrial-like adhesin protein VEGS12_06270 ENOG4105CW0 outer membrane usher protein VEGS12_06280 ENOG4108VEV chaperone VEGS12_06300 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase VEGS12_06310 ENOG4105DJ0 Poly(A) Polymerase VEGS12_06350 ENOG4107XID 2'-5' rna ligase VEGS12_06360 ENOG4105CQ7 ATP-dependent helicase VEGS12_06380 ENOG4105BZ4 penicillin-binding protein VEGS12_06390 ENOG4105E0K tonB-dependent siderophore receptor VEGS12_06400 ENOG4105E0A ABC, transporter VEGS12_06410 ENOG4105J76 Periplasmic binding protein VEGS12_06420 ENOG4105S6R Iron-hydroxamate transporter permease subunit VEGS12_06460 ENOG4105EN6 Membrane VEGS12_06470 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) VEGS12_06500 ENOG4105C0H protease VEGS12_06510 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR VEGS12_06550 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) VEGS12_06600 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) VEGS12_06610 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) VEGS12_06620 ENOG4105KNE Phosphatidate cytidylyltransferase VEGS12_06630 ENOG4105DZP Membrane-associated zinc metalloprotease VEGS12_06650 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) VEGS12_06660 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) VEGS12_06710 ENOG4105C0B DNA polymerase III (alpha subunit) VEGS12_06730 ENOG4105CXN decarboxylase VEGS12_06740 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase VEGS12_06750 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) VEGS12_06760 ENOG4105M1T rho-binding antiterminator VEGS12_06780 ENOG4108VWS Yaeq family VEGS12_06790 ENOG4108YZN class I peptide chain release factor VEGS12_06800 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion VEGS12_06820 ENOG4108UY0 (LipO)protein VEGS12_06830 ENOG4108UY0 (LipO)protein VEGS12_06850 ENOG4108R96 Methyltransferase, YaeB family VEGS12_06860 ENOG4108R8X outer membrane lipoprotein VEGS12_06870 ENOG4105D01 (LipO)protein VEGS12_06880 ENOG4108UMI ABC transporter, permease VEGS12_06890 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) VEGS12_06900 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase VEGS12_06910 ENOG4105CV8 reductase VEGS12_06920 ENOG4105HEI LysR family (Transcriptional regulator VEGS12_06940 ENOG4105F2W methyltransferase VEGS12_06950 ENOG4105E9H Lytic Murein transglycosylase VEGS12_06970 ENOG4105D1A Methyltransferase VEGS12_06990 ENOG4107RZZ dna polymerase iii epsilon subunit VEGS12_07000 ENOG410600K aminopeptidase VEGS12_07010 ENOG410600K aminopeptidase VEGS12_07040 ENOG4105GMB type VI secretion system effector, hcp1 family VEGS12_07090 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit VEGS12_07200 ENOG4108WC9 type VI secretion system effector, hcp1 family VEGS12_07210 ENOG4105CS6 Rhs element vgr protein VEGS12_07220 ENOG4105CNA YD repeat protein VEGS12_07250 ENOG410600T transposase VEGS12_07260 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase VEGS12_07270 ENOG4108WN0 inhibitor of vertebrate lysozyme VEGS12_07280 ENOG4107QPN acyl-Coa dehydrogenase VEGS12_07300 ENOG4105E7A Glutamine amidotransferase VEGS12_07310 ENOG4105F7V ErfK ybiS ycfS ynhG family protein VEGS12_07320 ENOG4105VXN addiction module toxin, RelE StbE family VEGS12_07340 ENOG4108YS0 lipoprotein YafL VEGS12_07390 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) VEGS12_07400 ENOG4108HYG acetyltransferase VEGS12_07420 ENOG4108S2Y peptide Chain Release factor VEGS12_07430 ENOG4105CIN aminoacyl-histidine dipeptidase VEGS12_07470 ENOG4105FCK Membrane VEGS12_07530 ENOG4108P8R VEGS12_07540 ENOG4108P8R VEGS12_07590 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 VEGS12_07620 ENOG4105BZU Histidine kinase VEGS12_07630 ENOG4108TUY outer membrane protein PgaA VEGS12_07640 ENOG4107BJW polysaccharide deacetylase VEGS12_07650 ENOG4105CND Glycosyl transferase, family 2 VEGS12_07670 ENOG4105D5M phosphate starvation-inducible protein VEGS12_07730 ENOG4105C5Y PTS System VEGS12_07760 ENOG4105D7K pfkb domain protein VEGS12_07790 ENOG4105MP0 transposase VEGS12_07810 ENOG4105EKQ RNA-directed DNA polymerase VEGS12_07840 ENOG4105E5H Transposase VEGS12_07890 ENOG4105F4K antigen 43 VEGS12_07900 ENOG4106H6R UPF0380 protein VEGS12_07910 ENOG4105MFG Antirestriction protein VEGS12_07920 ENOG4108YGG dna repair protein VEGS12_07950 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles VEGS12_08030 ENOG4107XAN XdhC and CoxI family VEGS12_08040 ENOG4105C7W Xanthine dehydrogenase VEGS12_08050 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding VEGS12_08060 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit VEGS12_08070 ENOG4105R3P Inner membrane protein yagU VEGS12_08090 ENOG4108UD7 cell wall organization VEGS12_08100 ENOG4106PYX Receptor VEGS12_08110 ENOG4108N3D putative enzyme VEGS12_08190 ENOG4108KBJ Inner membrane protein YkgB VEGS12_08200 ENOG41066GK UPF0379 protein ykgI VEGS12_08210 ENOG4107QN2 dihydrolipoyl dehydrogenase VEGS12_08220 ENOG4108K01 transcriptional regulator VEGS12_08230 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) VEGS12_08240 ENOG4107QR9 Iron-sulfur cluster binding protein VEGS12_08250 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) VEGS12_08300 ENOG4105C94 Transporter VEGS12_08330 ENOG4105BZU Histidine kinase VEGS12_08340 ENOG4108NUU Transcriptional regulator VEGS12_08350 ENOG4105SZ2 membrAne VEGS12_08360 ENOG4107SNB ankyrin repeat protein YahD VEGS12_08370 ENOG4105N16 Protein of unknown function (DUF2877) VEGS12_08380 ENOG4107R1Q Membrane protein FdrA VEGS12_08390 ENOG4107REC cytoplasmic protein VEGS12_08400 ENOG4105C5B carbamate kinase VEGS12_08410 ENOG4105DZC cytosine deaminase VEGS12_08430 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator VEGS12_08440 ENOG4105C2J ABC transporter VEGS12_08450 ENOG4105CNN ABC, transporter VEGS12_08460 ENOG4105CNN ABC, transporter VEGS12_08470 ENOG4105DQ4 alcohol dehydrogenase VEGS12_08490 ENOG4105E82 cytochrome subunit of dehydrogenase VEGS12_08500 ENOG4105TDT uncharacterized protein yahO VEGS12_08510 ENOG4108JU7 Transcriptional regulator VEGS12_08520 ENOG4105CR4 methylisocitrate lyase VEGS12_08530 ENOG4105BZN citrate synthase VEGS12_08540 ENOG4105DXD 2-methylcitrate dehydratase VEGS12_08550 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) VEGS12_08570 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin VEGS12_08580 ENOG4105DZC cytosine deaminase VEGS12_08590 ENOG4105DND Transcriptional regulator VEGS12_08600 ENOG4107B2H carbonic anhydrase VEGS12_08620 ENOG4105DJ2 Major Facilitator Superfamily VEGS12_08630 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) VEGS12_08640 ENOG4105CNT hydrolase family 2 VEGS12_08650 ENOG4105ETE Transcriptional regulator (LacI family VEGS12_08660 ENOG4108K2P TRANSCRIPTIONal VEGS12_08730 ENOG4108SC4 )-transporter VEGS12_08740 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme VEGS12_08780 ENOG4105SRB Uncharacterized protein yaiO VEGS12_08800 ENOG4108PBI Polysaccharide metabolism VEGS12_08810 ENOG4107W19 lmbE family VEGS12_08830 ENOG4106FTQ Taurine ABC transporter, periplasmic VEGS12_08850 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component VEGS12_08860 ENOG4105E2B Taurine dioxygenase VEGS12_08870 ENOG4105D52 delta-aminolevulinic acid dehydratase VEGS12_08890 ENOG4108PNB DNA-binding transcriptional regulator VEGS12_08900 ENOG4107R6D beta-lactam binding protein AmpH VEGS12_08910 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 VEGS12_08920 ENOG4107QS8 (LipO)protein VEGS12_08930 ENOG4105FR5 inner membrane protein YaiY VEGS12_08940 ENOG4105UNH Membrane VEGS12_08950 ENOG4105CPF Cell wall formation (By similarity) VEGS12_08970 ENOG4105G6Z alkaline phosphatase VEGS12_08980 ENOG4105VIF phosphate starvation-inducible protein VEGS12_08990 ENOG4105BZU Histidine kinase VEGS12_09000 ENOG4105II7 pyrroline-5-carboxylate reductase VEGS12_09030 ENOG4105SS3 VEGS12_09040 ENOG4105HBA AroM protein VEGS12_09080 ENOG4105DKQ ROK family VEGS12_09090 ENOG4105F27 Major Facilitator VEGS12_09100 ENOG4105EYH Exonuclease VEGS12_09110 ENOG4107RH8 nuclease SbcCD subunit D VEGS12_09120 ENOG4105CK6 Two component transcriptional regulator (Winged helix family VEGS12_09130 ENOG4105BZU Histidine kinase VEGS12_09140 ENOG4105CWM branched-chain amino acid transport system II carrier protein VEGS12_09150 ENOG4105C85 amino acid VEGS12_09160 ENOG4107R28 alpha amylase, catalytic region VEGS12_09200 ENOG4105VIE preprotein translocase, subunit YajC VEGS12_09210 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) VEGS12_09220 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) VEGS12_09230 ENOG4105N1F Hnh endonuclease VEGS12_09240 ENOG4105DRB nucleoside-specific channel-forming protein VEGS12_09250 ENOG4108KIC (LipO)protein VEGS12_09270 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) VEGS12_09280 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) VEGS12_09300 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) VEGS12_09310 ENOG4108ZAI phosphatidylglycerophosphatase a VEGS12_09320 ENOG4105CPC Aldo Keto reductase VEGS12_09340 ENOG4105CTB Polyprenyl synthetase VEGS12_09370 ENOG4107S0N DJ-1 family VEGS12_09380 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) VEGS12_09400 ENOG4107RDB Major Facilitator VEGS12_09450 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) VEGS12_09460 ENOG4105CCU oxidase (Subunit III) VEGS12_09470 ENOG4105BZ9 Cytochrome C oxidase, subunit I VEGS12_09480 ENOG4105E2S oxidase) subunit II VEGS12_09490 ENOG4105EYM Major Facilitator superfamily VEGS12_09500 ENOG4105IEY (LipO)protein VEGS12_09510 ENOG4105M85 Bola protein VEGS12_09550 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) VEGS12_09560 ENOG4105K70 DNA-binding protein VEGS12_09570 ENOG4105EIN peptidylprolyl cis-trans isomerase VEGS12_09580 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein VEGS12_09590 ENOG4108TGP Thioesterase superfamily protein VEGS12_09610 ENOG4108NFA extracellular solute-binding protein VEGS12_09630 ENOG4108XM1 transcriptional regulator AsnC family VEGS12_09640 ENOG4105BZ1 (ABC) transporter VEGS12_09650 ENOG4105BZ1 (ABC) transporter VEGS12_09660 ENOG4108YZA Nitrogen regulatory protein pii VEGS12_09670 ENOG4105BZU Histidine kinase VEGS12_09680 ENOG4105C29 acyl-CoA thioesterase VEGS12_09690 ENOG4108MNP Glycoprotein polysaccharide metabolism VEGS12_09700 ENOG41080UX Methyltransferase VEGS12_09710 ENOG4105KCV RNA signal recognition particle 4.5S RNA VEGS12_09720 ENOG41066DG (EAL) domain protein VEGS12_09730 ENOG4105GSJ Inner membrane protein ylaC VEGS12_09740 ENOG4108UW5 maltose o-acetyltransferase VEGS12_09750 ENOG4105KF5 hemolysin expression-modulating protein VEGS12_09760 ENOG4108UKR Biofilm formation regulator YbaJ VEGS12_09770 ENOG4105BZS acriflavin resistance protein VEGS12_09780 ENOG4105C1P efflux transporter, rnd family, mfp subunit VEGS12_09790 ENOG4107XI7 Tetr family transcriptional regulator VEGS12_09800 ENOG4105EGS Mechanosensitive ion channel VEGS12_09810 ENOG4106428 Protein of unknown function (DUF2496) VEGS12_09820 ENOG4108URS primosomal replication protein n'' VEGS12_09830 ENOG4105WD1 Membrane VEGS12_09850 ENOG4107QMP dna polymerase iii subunits gamma and tau VEGS12_09920 ENOG4107RE1 Inosine-guanosine kinase VEGS12_09930 ENOG4105CKD glutathione-regulated potassium-efflux system protein VEGS12_09940 ENOG4105EU0 Major facilitator Superfamily VEGS12_09950 ENOG4105CGH 5'-nucleotidase VEGS12_09960 ENOG4108Z66 YbaK ebsC protein VEGS12_09970 ENOG4105MBR gumn family VEGS12_09980 ENOG41081XE plasmid maintenance system antidote protein, xre family VEGS12_09990 ENOG4105C59 p-type ATPase VEGS12_10000 ENOG4105CSV Glutaminase VEGS12_10010 ENOG4107RY6 amino acid VEGS12_10020 ENOG4108Z6Z Transcriptional regulator VEGS12_10030 ENOG4105G5H Membrane VEGS12_10040 ENOG4107QX8 SPFH domain, Band 7 family protein VEGS12_10050 ENOG41083J0 (ABC) transporter VEGS12_10060 ENOG4105C4B ABC transporter, permease VEGS12_10070 ENOG4107QR8 Thioredoxin VEGS12_10080 ENOG4105E1F short-chain dehydrogenase reductase VEGS12_10090 ENOG4108UJV acyl-CoA thioesterase i VEGS12_10100 ENOG4108I0Y (ABC) transporter VEGS12_10110 ENOG4105CV6 ABC transporter, permease VEGS12_10120 ENOG4105CNA YD repeat protein VEGS12_10180 ENOG4107653 Transcriptional regulator VEGS12_10200 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region VEGS12_10210 ENOG41060W2 glyoxylate carboligase VEGS12_10220 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) VEGS12_10230 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase VEGS12_10240 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease VEGS12_10260 ENOG4105DTE Xanthine uracil vitamin C permease VEGS12_10270 ENOG4105BZW Glycerate kinase VEGS12_10280 ENOG4105S0E allantoin catabolism protein VEGS12_10290 ENOG4105CE7 Amidase, hydantoinase carbamoylase family VEGS12_10300 ENOG4105DG4 malate L-lactate dehydrogenase VEGS12_10310 ENOG4107R1Q Membrane protein FdrA VEGS12_10320 ENOG4107REC cytoplasmic protein VEGS12_10330 ENOG4105G5A Protein of unknown function (DUF2877) VEGS12_10340 ENOG4105C5B carbamate kinase VEGS12_10350 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit VEGS12_10360 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) VEGS12_10380 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) VEGS12_10400 ENOG4105S2T inner membrane protein YbcI VEGS12_10410 ENOG4105WQ3 Rna-binding protein VEGS12_10420 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) VEGS12_10430 ENOG4108WDE Fimbrial protein VEGS12_10440 ENOG4108AF8 Chaperone VEGS12_10450 ENOG4105CW0 outer membrane usher protein VEGS12_10460 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) VEGS12_10470 ENOG4108ZI2 Fimbrial protein VEGS12_10480 ENOG4108Q9V regulatoR VEGS12_10500 ENOG4105QUW VEGS12_10510 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit VEGS12_10520 ENOG410802X bacteriophage n4 adsorption protein b VEGS12_10530 ENOG410600T transposase VEGS12_10540 ENOG4105CNA YD repeat protein VEGS12_10570 ENOG4105CNA YD repeat protein VEGS12_10590 ENOG4105CS6 Rhs element vgr protein VEGS12_10600 ENOG4105GR3 Histidine kinase VEGS12_10610 ENOG4105CK6 Two component transcriptional regulator (Winged helix family VEGS12_10620 ENOG4105ENJ RND efflux system, outer membrane lipoprotein VEGS12_10630 ENOG410624V efflux system protein VEGS12_10640 ENOG4105EP1 Efflux transporter rnd family, mfp subunit VEGS12_10650 ENOG4108IJF Heavy metal efflux pump, CzcA VEGS12_10660 ENOG4105C85 amino acid VEGS12_10670 ENOG4105CUY Mechanosensitive ion channel VEGS12_10680 ENOG4108RCM Nitroreductase VEGS12_10690 ENOG4105MSB protein, conserved in bacteria VEGS12_10700 ENOG4105WQ6 Membrane VEGS12_10720 ENOG4107635 Hok Gef family protein VEGS12_10740 ENOG4108TSE Transferase VEGS12_10750 ENOG4107RNH Outer membrane receptor FepA VEGS12_10760 ENOG4105E93 esterase VEGS12_10770 ENOG41085A6 mbth domain-containing protein VEGS12_10780 ENOG4105C0W non-ribosomal peptide synthetase VEGS12_10790 ENOG4108QY5 Ferric enterobactin transport protein VEGS12_10800 ENOG4105E0A ABC, transporter VEGS12_10810 ENOG4105TVJ transport system, permease VEGS12_10820 ENOG4105DQ5 transport system permease protein VEGS12_10840 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein VEGS12_10850 ENOG4105E4F Isochorismate synthase VEGS12_10860 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase VEGS12_10870 ENOG4105WQI isochorismatase VEGS12_10880 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase VEGS12_10890 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) VEGS12_10900 ENOG4105D22 carbon starvation protein VEGS12_10910 ENOG4105VCD cytoplasmic protein VEGS12_10920 ENOG4107SCQ Iron-containing alcohol dehydrogenase VEGS12_10930 ENOG4105CHM Aminotransferase VEGS12_10940 ENOG4105GTN ParB Domain Protein Nuclease VEGS12_10950 ENOG4105BZV Phosphoadenosine phosphosulfate reductase VEGS12_10960 ENOG4105DQS Transcriptional regulator VEGS12_10970 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase VEGS12_10980 ENOG4105D3R alkyl hydroperoxide reductase VEGS12_10990 ENOG4108JU3 Alkyl hydroperoxide reductase VEGS12_11000 ENOG4108U51 Universal stress protein VEGS12_11010 ENOG4105E2A Dehydrogenase VEGS12_11020 ENOG4105NXH GreA GreB family elongation factor VEGS12_11030 ENOG4105KTS ribonuclease VEGS12_11040 ENOG4107QPK )-transporter VEGS12_11070 ENOG4105CHY citrate lyase, alpha VEGS12_11080 ENOG4105CI0 Citrate lyase VEGS12_11100 ENOG4105DUA (citrate (pro-3S)-lyase ligase VEGS12_11110 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism VEGS12_11120 ENOG4106YYS transcriptional regulatory protein VEGS12_11130 ENOG4105CEE C4-dicarboxylate transporter VEGS12_11140 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) VEGS12_11180 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) VEGS12_11200 ENOG41064T2 transcriptional regulator, lysR family VEGS12_11230 ENOG4105DZ1 carboxypeptidase VEGS12_11240 ENOG4105K6T rare lipoprotein A VEGS12_11250 ENOG4105CNI cell division protein FtsW VEGS12_11260 ENOG4105CJN penicillin-binding protein VEGS12_11280 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) VEGS12_11290 ENOG4108TGR phosphatase VEGS12_11310 ENOG4105DJF DNA polymerase III, delta' subunit VEGS12_11340 ENOG4107PAI alpha helical protein VEGS12_11350 ENOG4105EUU Sel1 domain protein repeat-containing protein VEGS12_11360 ENOG41069CF Protein of unknown function (DUF1266) VEGS12_11370 ENOG4105QFC Hsc56 co-chaperone of HscC VEGS12_11380 ENOG4107JFD Sel1 repeat VEGS12_11390 ENOG41069CF Protein of unknown function (DUF1266) VEGS12_11400 ENOG4105QFC Hsc56 co-chaperone of HscC VEGS12_11410 ENOG4105F7F Chaperone VEGS12_11430 ENOG4105CDA abc transporter atp-binding protein VEGS12_11440 ENOG4105DRP amino acid AbC transporter VEGS12_11450 ENOG4105EAD ABC transporter VEGS12_11460 ENOG4107RP9 extracellular solute-binding protein, family 3 VEGS12_11480 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) VEGS12_11490 ENOG4108JU5 Magnesium and cobalt efflux protein VEGS12_11510 ENOG4105C9A Phoh family VEGS12_11530 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family VEGS12_11540 ENOG4105CAQ asparagine synthetase VEGS12_11550 ENOG4105D4U had-superfamily hydrolase, subfamily iia VEGS12_11560 ENOG4105E2R ROK family VEGS12_11570 ENOG4105CE4 GlcNAc 6-P deacetylase VEGS12_11590 ENOG4105CI1 PTS System VEGS12_11620 ENOG4105GX6 (LipO)protein VEGS12_11630 ENOG41090R7 Ferric uptake VEGS12_11640 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) VEGS12_11650 ENOG4105NNH LexA regulated protein VEGS12_11660 ENOG4105EV9 Alpha Beta Hydrolase VEGS12_11670 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) VEGS12_11680 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 VEGS12_11690 ENOG4105D5Q Arginine ornithine antiporter VEGS12_11700 ENOG4105CXN decarboxylase VEGS12_11710 ENOG4105EEX Two component transcriptional regulator (Winged helix family VEGS12_11720 ENOG4105C08 Histidine kinase VEGS12_11760 ENOG4105XIQ Protein of unknown function (DUF2517) VEGS12_11770 ENOG4105CNA YD repeat protein VEGS12_11780 ENOG4106R09 VEGS12_11790 ENOG410600T transposase VEGS12_11800 ENOG410600T transposase VEGS12_11810 ENOG4107SEY Conserved Protein VEGS12_11820 ENOG4105CVP deoxyribo-dipyrimidine photolyase VEGS12_11830 ENOG4105DUX Transporter VEGS12_11840 ENOG4107QNR UPF0135 protein VEGS12_11850 ENOG4105P4J Allophanate hydrolase, subunit 1 VEGS12_11860 ENOG4107R7A Allophanate hydrolase subunit 2 VEGS12_11890 ENOG4108KK1 membrane protein AbrB duplication VEGS12_11900 ENOG4108MY7 Fimbrial VEGS12_11910 ENOG4108TTM chaperone VEGS12_11920 ENOG4106PG1 outer membrane usher protein VEGS12_11930 ENOG4106UBK fimbrial-like adhesin protein VEGS12_11940 ENOG4105BZN citrate synthase VEGS12_11960 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit VEGS12_11970 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein VEGS12_11980 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) VEGS12_11990 ENOG4105E33 succinate dehydrogenase VEGS12_12000 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 VEGS12_12010 ENOG4105C7S Dehydrogenase VEGS12_12030 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha VEGS12_12040 ENOG4105FDP GntR family transcriptional regulator VEGS12_12050 ENOG4105DM4 PTS System VEGS12_12060 ENOG4105C8I hydrolase, family 38 VEGS12_12080 ENOG4105C4M (Ubiquinol oxidase) subunit I VEGS12_12090 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii VEGS12_12100 ENOG4105KJB cyd operon protein YbgE VEGS12_12110 ENOG4107YD3 Thioesterase VEGS12_12120 ENOG4105E02 MotA TolQ exbB proton channel VEGS12_12140 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA VEGS12_12160 ENOG4105KCK Peptidoglycan-associated lipoprotein VEGS12_12170 ENOG4105UFD tol-pal system protein YbgF VEGS12_12190 ENOG4106Z1T Nicotinamide Mononucleotide Transporter VEGS12_12200 ENOG4105PGM cation diffusion facilitator family transporter VEGS12_12210 ENOG4105JND homeobox protein VEGS12_12220 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) VEGS12_12240 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) VEGS12_12260 ENOG4105F0Z galactose-1-phosphate uridylyltransferase VEGS12_12270 ENOG4105CMR udp-glucose 4-epimerase VEGS12_12280 ENOG4105DKW ABC transporter VEGS12_12290 ENOG4105F4R Transcriptional regulator mode VEGS12_12310 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein VEGS12_12320 ENOG4105E0C molybdate abc transporter VEGS12_12340 ENOG4108K4B hydrolase VEGS12_12360 ENOG4105F04 LysR family Transcriptional regulator VEGS12_12370 ENOG4105C7F AcnD-accessory protein PrpF VEGS12_12380 ENOG4107QPK )-transporter VEGS12_12390 ENOG4107QM5 aconitate hydratase VEGS12_12400 ENOG4105NBR Pectinesterase VEGS12_12410 ENOG4108V1U phospholipid-binding protein VEGS12_12420 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) VEGS12_12450 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) VEGS12_12460 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) VEGS12_12480 ENOG4105CHW UPF0052 protein VEGS12_12500 ENOG4108RIR Molybdenum cofactor biosynthesis protein VEGS12_12520 ENOG4105M00 molybdopterin converting factor, subunit 1 VEGS12_12530 ENOG4108ZAF Molybdopterin VEGS12_12540 ENOG4105HFZ Membrane VEGS12_12560 ENOG410733J conserved inner membrane protein VEGS12_12570 ENOG4107UXM Membrane VEGS12_12580 ENOG4105DZQ phospholipase D Transphosphatidylase VEGS12_12590 ENOG4105X23 Endonuclease Exonuclease phosphatase VEGS12_12600 ENOG4105I9U inner membrane protein ybhQ VEGS12_12610 ENOG4107QWP ABC-2 type transporter VEGS12_12620 ENOG4107QWP ABC-2 type transporter VEGS12_12630 ENOG4105CJ1 ABC, transporter VEGS12_12650 ENOG4107MVR Transcriptional regulator VEGS12_12660 ENOG4105C1J atp-dependent rna helicase VEGS12_12670 ENOG4108UV1 cellular component movement VEGS12_12680 ENOG4105DVT helicase VEGS12_12690 ENOG4108MTB glycosyl transferase family VEGS12_12700 ENOG4105DG4 malate L-lactate dehydrogenase VEGS12_12710 ENOG4105VR4 UPF0379 protein ybiJ VEGS12_12720 ENOG4105KSC Transcriptional regulator, TraR DksA family VEGS12_12740 ENOG4108IU3 tonb-dependent siderophore receptor VEGS12_12750 ENOG4105ZY9 UPF0379 protein ybiM VEGS12_12770 ENOG4105D8X mechanosensitive ion channel VEGS12_12780 ENOG4105CDA abc transporter atp-binding protein VEGS12_12790 ENOG4105E5Q amino acid AbC transporter VEGS12_12800 ENOG4107R0W ABC transporter VEGS12_12820 ENOG4107AQZ Membrane VEGS12_12830 ENOG4108T1M outer membrane protein x VEGS12_12840 ENOG4108I6E Sulfatase VEGS12_12860 ENOG4105KST dependent repressor VEGS12_12870 ENOG4105F4P )-transporter VEGS12_12880 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein VEGS12_12890 ENOG4105C5H ABC transporter VEGS12_12910 ENOG41072TH Protein of unknown function (DUF1479) VEGS12_12920 ENOG4108HCJ Hydrolase VEGS12_12940 ENOG4105F1A Pyruvate formate-lyase VEGS12_12950 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) VEGS12_12960 ENOG4105D06 uba thif-type nad fad binding protein VEGS12_12970 ENOG4105CVM Molybdenum cofactor synthesis domain protein VEGS12_12980 ENOG4105D44 asparaginase VEGS12_13030 ENOG4105BZU Histidine kinase VEGS12_13040 ENOG41064RH membrane protein YliF VEGS12_13060 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway VEGS12_13070 ENOG4105D8V Glucose sorbosone dehydrogenase VEGS12_13080 ENOG4108TGY Glutathione S-transferase VEGS12_13090 ENOG4105DZ1 carboxypeptidase VEGS12_13100 ENOG4107FB0 transcriptional regulator DeoR family VEGS12_13110 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase VEGS12_13120 ENOG4107QF7 multi-drug VEGS12_13140 ENOG4108HCJ Hydrolase VEGS12_13150 ENOG4106UW1 Major Facilitator superfamily VEGS12_13160 ENOG4108RFG Tetr family transcriptional regulator VEGS12_13170 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) VEGS12_13200 ENOG4105MEH VEGS12_13250 ENOG4105KSC Transcriptional regulator, TraR DksA family VEGS12_13260 ENOG4105DFE Dna adenine methylase VEGS12_13310 ENOG4105ED4 portal protein VEGS12_13500 ENOG4108US3 tail fiber assembly VEGS12_13510 ENOG4105PTU response to oxidative stress VEGS12_13530 ENOG4108C33 Resolvase VEGS12_13600 ENOG4105ZTC transcriptional activator, Ogr delta VEGS12_13620 ENOG41090BQ Glutaredoxin VEGS12_13630 ENOG4108DBC nitroreductase VEGS12_13650 ENOG4108RMJ sensory transduction regulator VEGS12_13660 ENOG4107RUE extracellular solute-binding protein family 1 VEGS12_13670 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) VEGS12_13680 ENOG4105F38 ABC transporter, permease VEGS12_13690 ENOG4105D38 putrescine abc transporter VEGS12_13700 ENOG4105RBQ inner membrane protein ybjO VEGS12_13720 ENOG4106TNF Periplasmic binding protein VEGS12_13730 ENOG4105DMR ABC, transporter VEGS12_13740 ENOG4105GBT ABC transporter VEGS12_13750 ENOG4106PMH Extracellular solute-binding protein family 3 VEGS12_13760 ENOG4105E5Z arginine transporter ATP-binding subunit VEGS12_13770 ENOG41064MM (LipO)protein VEGS12_13790 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase VEGS12_13800 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase VEGS12_13810 ENOG4105CGD Nad-dependent epimerase dehydratase VEGS12_13820 ENOG4105C5W Aldolase VEGS12_13830 ENOG4105C7K acetolactate synthase VEGS12_13840 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) VEGS12_13860 ENOG4105DWU Membrane VEGS12_13870 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) VEGS12_13880 ENOG4105CPB ATP-dependent endonuclease of the OLD family VEGS12_13890 ENOG4108MJ5 VirK protein VEGS12_13900 ENOG4105DJY efflux transporter, rnd family, mfp subunit VEGS12_13920 ENOG4105VEQ Cold shock protein VEGS12_13940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit VEGS12_13950 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) VEGS12_13970 ENOG4108JJ8 (ABC) transporter VEGS12_13980 ENOG4108JJ9 ABC, transporter VEGS12_13990 ENOG4105C3M thioredoxin reductase VEGS12_14010 ENOG4105CNU cell division protein FtsK VEGS12_14030 ENOG4105D1H recombination factor protein RarA VEGS12_14050 ENOG4107QY8 reductase VEGS12_14060 ENOG4105QAX Iron-sulfur VEGS12_14070 ENOG4107KGK dmso reductase anchor subunit VEGS12_14080 ENOG4105CHJ isochorismatase hydrolase VEGS12_14100 ENOG4105E5D amino acid VEGS12_14110 ENOG410642W LysR family Transcriptional regulator VEGS12_14120 ENOG4108X0B nad(p)h dehydrogenase (quinone) VEGS12_14130 ENOG4105F1A Pyruvate formate-lyase VEGS12_14140 ENOG4105C6N Formate acetyltransferase VEGS12_14150 ENOG4105TMB Formate nitrite transporter VEGS12_14160 ENOG4105DDY UPF0142 protein ycaO VEGS12_14170 ENOG4107VMU Membrane VEGS12_14200 ENOG4108K0D peptidase, M48 VEGS12_14220 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) VEGS12_14240 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 VEGS12_14250 ENOG4105BZ1 (ABC) transporter VEGS12_14270 ENOG4105T0Z Conserved Protein VEGS12_14300 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups VEGS12_14310 ENOG4107S90 membrAne VEGS12_14320 ENOG4106371 Methyltransferase VEGS12_14340 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) VEGS12_14360 ENOG4105DIT ErfK YbiS YcfS YnhG family protein VEGS12_14370 ENOG4105EAQ (twin-arginine translocation) pathway signal VEGS12_14380 ENOG4105C5X domain protein VEGS12_14390 ENOG4105CGF Aromatic amino acid aminotransferase VEGS12_14410 ENOG4105FCK Membrane VEGS12_14440 ENOG4105CD8 aminopeptidase N VEGS12_14460 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component VEGS12_14480 ENOG4105GVF (ABC) transporter VEGS12_14490 ENOG4108UZX fmn reductase VEGS12_14500 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon VEGS12_14510 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae VEGS12_14520 ENOG4105CW0 outer membrane usher protein VEGS12_14530 ENOG4108MDY Fimbrial VEGS12_14540 ENOG4105Q7J Fimbrial VEGS12_14550 ENOG4105MX3 Fimbrial VEGS12_14560 ENOG4106PH7 chaperone VEGS12_14580 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) VEGS12_14590 ENOG4105QVC MOSC domain-containing protein VEGS12_14610 ENOG4105C5H ABC transporter VEGS12_14620 ENOG4105F1S paraquat-inducible protein a VEGS12_14630 ENOG4105DY2 Paraquat-inducible protein b VEGS12_14640 ENOG4108Q2G (LipO)protein VEGS12_14650 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) VEGS12_14670 ENOG4105DAN ATP-dependent protease VEGS12_14690 ENOG4105UYK outer membrane protein a VEGS12_14720 ENOG4108RZ1 DNA transformation protein VEGS12_14730 ENOG4105EM2 membrane VEGS12_14740 ENOG410901E Membrane VEGS12_14750 ENOG41088T4 Helicase IV VEGS12_14780 ENOG4105K4P CoA-binding domain protein VEGS12_14810 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 VEGS12_14820 ENOG4108Z0T Part of a sulfur-relay system (By similarity) VEGS12_14830 ENOG4108MN8 Membrane VEGS12_14840 ENOG4105E3S small subunit VEGS12_14850 ENOG4105DPX Hydrogenase, large subunit VEGS12_14860 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit VEGS12_14870 ENOG4108USZ hydrogenase VEGS12_14880 ENOG4108VXY Hydrogenase-1 operon protein HyaE VEGS12_14890 ENOG4105MVP hydrogenase-1 operon protein HyaF VEGS12_14900 ENOG4105C4M (Ubiquinol oxidase) subunit I VEGS12_14910 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii VEGS12_14920 ENOG4105D6F Phosphatase VEGS12_14930 ENOG4105D75 Capsular exopolysaccharide family VEGS12_14940 ENOG4107ZF2 Phosphatase VEGS12_14950 ENOG4105DAY polysaccharide export protein VEGS12_14960 ENOG4105E3R (LipO)protein VEGS12_14970 ENOG4108W78 Pfam:DUF1017 VEGS12_14980 ENOG4108Y9B (LipO)protein VEGS12_15010 ENOG41060EU Cold shock-like protein VEGS12_15020 ENOG4105VEQ Cold shock protein VEGS12_15030 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation VEGS12_15040 ENOG4105HEE Binding Domain protein VEGS12_15050 ENOG4105BZU Histidine kinase VEGS12_15060 ENOG4108SV3 Tmao reductase system periplasmic protein tort VEGS12_15070 ENOG4106WF9 DNA-binding transcriptional regulator TorR VEGS12_15080 ENOG4105CUW cytochrome C-TYPE protein VEGS12_15090 ENOG4108J2R molybdopterin oxidoreductase VEGS12_15140 ENOG4105D6F Phosphatase VEGS12_15150 ENOG4105XH3 VEGS12_15170 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 VEGS12_15180 ENOG4105C2W permease VEGS12_15230 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) VEGS12_15250 ENOG4108R86 Transcriptional regulator VEGS12_15260 ENOG4105C26 Dehydrogenase VEGS12_15280 ENOG4105CK7 Sodium proline symporter VEGS12_15300 ENOG410650H (LipO)protein VEGS12_15320 ENOG4105D5M phosphate starvation-inducible protein VEGS12_15340 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase VEGS12_15360 ENOG4107XHZ cytoplasmic chaperone TorD family protein VEGS12_15370 ENOG4108UQ5 membrane protein YcdZ VEGS12_15380 ENOG4105P8Q Curli production assembly transport component CsgG VEGS12_15390 ENOG4108WYR Curli production assembly transport component, CsgF VEGS12_15400 ENOG4108XDW curli assembly protein CsgE VEGS12_15410 ENOG41086KC Transcriptional regulator VEGS12_15420 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers VEGS12_15430 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin VEGS12_15460 ENOG4108UVJ appr-1-p processing domain protein VEGS12_15470 ENOG4107RZC phospholipase d VEGS12_15500 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) VEGS12_15510 ENOG4105NAC (LipO)protein VEGS12_15520 ENOG4108W47 Acidic protein msyB VEGS12_15540 ENOG4105D1S lipid A biosynthesis VEGS12_15560 ENOG4108YYC ycei family VEGS12_15570 ENOG4105DS1 cytochrome b561 VEGS12_15590 ENOG4105PVA Biofilm formation regulatory protein BssS VEGS12_15600 ENOG4105MEA DNA damage-inducible protein i VEGS12_15620 ENOG4105F3T (LipO)protein VEGS12_15630 ENOG4105E9S glutaredoxin 2 VEGS12_15650 ENOG4105D9U N-acetyltransferase VEGS12_15670 ENOG4105EP9 oxidoreductase VEGS12_15680 ENOG4105CJR Integral membrane protein (MviN VEGS12_15690 ENOG4105QVD Flagella synthesis protein FlgN VEGS12_15700 ENOG4105M9M anti-sigma28 factor FlgM VEGS12_15710 ENOG4105CKS Flagella basal body P-ring formation protein flgA VEGS12_15720 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) VEGS12_15730 ENOG4108ZC9 flagellar basal-body rod protein flgc VEGS12_15740 ENOG4105W00 Flagellar hook capping protein VEGS12_15750 ENOG4105BZE flagellar hook protein, FlgE VEGS12_15760 ENOG4108KPB Flagellar basal-body rod protein FlgF VEGS12_15770 ENOG4105CGA flagellar basal-body rod protein FlgG VEGS12_15800 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj VEGS12_15810 ENOG4105E1Q flagellar hook-associated protein VEGS12_15820 ENOG4105DTJ flagellar hook-associated protein VEGS12_15830 ENOG4107QQB Ribonuclease E VEGS12_15840 ENOG4105EI2 Pseudouridine synthase VEGS12_15850 ENOG4108UHJ MAF-like protein VEGS12_15860 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein VEGS12_15900 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase VEGS12_15910 ENOG4105CHR reductase VEGS12_15920 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) VEGS12_15930 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) VEGS12_15940 ENOG4105YAZ 4-amino-4-deoxychorismate lyase VEGS12_15950 ENOG4105HHA aminodeoxychorismate lyase VEGS12_15970 ENOG4107QRG dna polymerase iii VEGS12_15980 ENOG4105F8V Hydrolase, tatD family VEGS12_15990 ENOG4105CI1 PTS System VEGS12_16000 ENOG4105CNM Receptor VEGS12_16010 ENOG4105K59 histidine triad (HIT) protein VEGS12_16020 ENOG41090DQ Lipoprotein VEGS12_16030 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) VEGS12_16070 ENOG4105CEP NADH dehydrogenase VEGS12_16080 ENOG4107MBR 17 kDa surface antigen VEGS12_16090 ENOG4108IND Tetr family transcriptional regulator VEGS12_16100 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction VEGS12_16110 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein VEGS12_16120 ENOG4108JA2 transcriptioN-repair coupling factor VEGS12_16130 ENOG4105IQC Inner membrane protein YcfT VEGS12_16140 ENOG4105D60 lipoprotein releasing system transmembrane protein VEGS12_16150 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) VEGS12_16160 ENOG4105D60 lipoprotein releasing system transmembrane protein VEGS12_16180 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) VEGS12_16210 ENOG4107RUE extracellular solute-binding protein family 1 VEGS12_16220 ENOG4105D38 putrescine abc transporter VEGS12_16240 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) VEGS12_16270 ENOG4105EZE Cupin 4 family protein VEGS12_16280 ENOG4105IFJ Histidine kinase VEGS12_16290 ENOG4105XJC Two component transcriptional regulator (Winged helix family VEGS12_16300 ENOG4107QTF adenylosuccinate lyase VEGS12_16340 ENOG4108R99 pseudouridine synthase VEGS12_16350 ENOG4108HMX isocitrate dehydrogenase (NADP) VEGS12_16360 ENOG41064WM Uncharacterized protein YcgX VEGS12_16370 ENOG4108XDN Transcriptional regulator VEGS12_16420 ENOG410658X VEGS12_16460 ENOG4107QMS site-determining protein VEGS12_16480 ENOG4105S66 prophage protein VEGS12_16490 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium VEGS12_16510 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase VEGS12_16530 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells VEGS12_16540 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells VEGS12_16550 ENOG4105KT5 UmuD protein VEGS12_16560 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) VEGS12_16570 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) VEGS12_16600 ENOG4105ED1 spovr family VEGS12_16620 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) VEGS12_16640 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A VEGS12_16660 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division VEGS12_16670 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) VEGS12_16710 ENOG4105VDH Dihydroxyacetone kinase VEGS12_16720 ENOG4108UTZ Dihydroxyacetone kinase VEGS12_16730 ENOG4105CMT Dihydroxyacetone kinase VEGS12_16740 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family VEGS12_16750 ENOG4105I1J Autotransporter VEGS12_16760 ENOG4105I1J Autotransporter VEGS12_16780 ENOG4105C3G gtp-binding protein VEGS12_16800 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria VEGS12_16810 ENOG4105CHH sulfate transporter VEGS12_16820 ENOG4105C5T Phosphoribosyl pyrophosphate synthase VEGS12_16870 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) VEGS12_16880 ENOG4108YY7 Invasion gene expression up-regulator SirB VEGS12_16890 ENOG41063JG Transcriptional regulator VEGS12_16920 ENOG4105EWV Sodium calcium exchanger membrane region VEGS12_16930 ENOG4105WS7 Cation transport regulator VEGS12_16940 ENOG4108NH8 Cation transport protein VEGS12_16950 ENOG41090EX DsrE family VEGS12_16960 ENOG4105ID0 Putative invasin VEGS12_16970 ENOG4105WH1 Two component transcriptional regulator luxr family VEGS12_16980 ENOG4105BZU Histidine kinase VEGS12_17000 ENOG4105DQQ Major facilitator superfamily MFS_1 VEGS12_17010 ENOG4105CRU nitrate reductase, alpha subunit VEGS12_17020 ENOG4108IUE nitrate reductase beta subunit VEGS12_17030 ENOG4105R3A Nitrate reductase VEGS12_17040 ENOG41076YT nitrate reductase, gamma subunit VEGS12_17060 ENOG4105CIY formyltetrahydrofolate deformylase VEGS12_17070 ENOG4105K5B UPF0225 protein VEGS12_17080 ENOG4105D78 K07001 NTE family protein VEGS12_17090 ENOG4105I93 response regulator VEGS12_17100 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase VEGS12_17110 ENOG4108SAU DNA-binding protein H-ns VEGS12_17120 ENOG4107104 thymidine kinase VEGS12_17130 ENOG4105C0A alcohol dehydrogenase VEGS12_17140 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein VEGS12_17150 ENOG4108J59 Extracellular solute-binding protein, family 5 VEGS12_17160 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component VEGS12_17170 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component VEGS12_17180 ENOG4105C3U ABC transporter VEGS12_17190 ENOG4108JQ7 (ABC) transporter VEGS12_17220 ENOG4107SVH Potassium channel protein VEGS12_17230 ENOG4105K9H YciI-like protein VEGS12_17240 ENOG410822N TonB family VEGS12_17250 ENOG4105NAU thioesterase Superfamily protein VEGS12_17280 ENOG4105EIF outer membrane protein W VEGS12_17290 ENOG4108N8X transition metal ion binding VEGS12_17300 ENOG4108Z9Z response to DNA damage stimulus VEGS12_17340 ENOG4105DK0 Indole-3-glycerol phosphate synthase VEGS12_17350 ENOG4108EFP Anthranilate synthase component II VEGS12_17360 ENOG4105CRQ synthase (Component I) VEGS12_17370 ENOG4105DB7 PHP domain protein VEGS12_17380 ENOG4107RTD sua5 ycio yrdc ywlc family protein VEGS12_17390 ENOG4105FE9 pseudouridine synthase VEGS12_17400 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase VEGS12_17410 ENOG4105UBK short-chain dehydrogenase reductase VEGS12_17420 ENOG4105ERU peptidase VEGS12_17430 ENOG4105RKX Protein of unknown function (DUF2498) VEGS12_17440 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) VEGS12_17450 ENOG4107R11 Transcriptional regulator VEGS12_17480 ENOG4107QM5 aconitate hydratase VEGS12_17500 ENOG4105EYK Phosphatidylglycerophosphatase B VEGS12_17510 ENOG4105Q4A inner membrane protein yciS VEGS12_17520 ENOG4105CFV Tetratricopeptide repeat protein VEGS12_17540 ENOG4108ZJT translation initiation factor, Sui1 VEGS12_17560 ENOG4105N2W Transcriptional regulator VEGS12_17570 ENOG410643D UPF0509 protein VEGS12_17580 ENOG4105BZU Histidine kinase VEGS12_17600 ENOG4105Q4T oxidoreductase VEGS12_17610 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH VEGS12_17620 ENOG4105WDY DNA (cytosine-5-)-methyltransferase VEGS12_17630 ENOG4108JQ2 peptide transport system atp-binding protein VEGS12_17640 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein VEGS12_17650 ENOG4108EU3 peptide transport system, permease VEGS12_17660 ENOG4108I5W peptide transport system, permease protein VEGS12_17670 ENOG4108HIY periplasmic VEGS12_17680 ENOG4105N0E Protein of unknown function (DUF2543) VEGS12_17690 ENOG4105CUB amino acid VEGS12_17700 ENOG4105CFQ glutamine synthetase VEGS12_17710 ENOG4108Z86 Glutamine amidotransferase VEGS12_17720 ENOG4107VRI Transcriptional regulator VEGS12_17730 ENOG4105C26 Dehydrogenase VEGS12_17740 ENOG4105CJP fad dependent oxidoreductase VEGS12_17750 ENOG4108JPW Aminotransferase VEGS12_17760 ENOG4105E51 psp operon transcriptional activator VEGS12_17770 ENOG41087YS Phage shock protein A VEGS12_17780 ENOG4105YYT phage shock protein B VEGS12_17790 ENOG4105FM1 phage shock protein C VEGS12_17800 ENOG4105NNG Peripheral inner membrane phage-shock protein VEGS12_17810 ENOG4105K8Z Phage shock protein VEGS12_17820 ENOG4107QW3 Sucrose phosphorylase VEGS12_17830 ENOG4105WEM extracellular solute-binding protein VEGS12_17840 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component VEGS12_17850 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component VEGS12_17860 ENOG4107RRD Dehydrogenase VEGS12_17870 ENOG4107TYA transient receptor potential locus VEGS12_17880 ENOG4105CK5 oxidoreductase VEGS12_17890 ENOG4105C71 hydrolase family 65, central catalytic VEGS12_17900 ENOG4107URF beta-phospho-glucomutase VEGS12_17910 ENOG4108IJ9 (ABC) transporter VEGS12_17920 ENOG4107EFV Outer membrane protein G VEGS12_17930 ENOG4105FKQ transcriptional regulator VEGS12_17940 ENOG4105CM6 amino acid regulated cytosolic protein VEGS12_17960 ENOG4108JU8 Transcriptional regulator VEGS12_17970 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) VEGS12_17980 ENOG4107S8C mandelate racemase muconate lactonizing VEGS12_17990 ENOG4105KXI murein peptide amidase A VEGS12_18010 ENOG4105ENX hydrolase VEGS12_18020 ENOG4105EQ2 LysR family Transcriptional regulator VEGS12_18030 ENOG4107QSI ABC, transporter VEGS12_18040 ENOG4105D64 Mechanosensitive ion channel VEGS12_18050 ENOG4105S5I Membrane VEGS12_18060 ENOG4105Q9Y Universal stress protein VEGS12_18070 ENOG4105DS0 Transcriptional regulator, Crp Fnr family VEGS12_18080 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) VEGS12_18090 ENOG4105CFC Transporter VEGS12_18100 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B VEGS12_18110 ENOG4105CH2 amidohydrolase VEGS12_18120 ENOG4106KR7 LysR family Transcriptional regulator VEGS12_18130 ENOG4108DG9 Smr protein MutS2 VEGS12_18140 ENOG4105BZU Histidine kinase VEGS12_18160 ENOG4105C1J atp-dependent rna helicase VEGS12_18180 ENOG4107R08 Integrase VEGS12_18190 ENOG4107160 Rac prophage VEGS12_18200 ENOG41070YT Rac prophage VEGS12_18210 ENOG4106YAH restriction alleviation and modification enhancement VEGS12_18220 ENOG4108PNI recT protein VEGS12_18230 ENOG41076J9 exonuclease VIII VEGS12_18250 ENOG4107C82 Rac prophage VEGS12_18330 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) VEGS12_18350 ENOG4105C94 Transporter VEGS12_18380 ENOG4108NH8 Cation transport protein VEGS12_18390 ENOG4105F27 Major Facilitator VEGS12_18420 ENOG4105RWQ Protein of unknown function (DUF1364) VEGS12_18460 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA VEGS12_18490 ENOG4105QFS Lysis protein S homolog from lambdoid prophage VEGS12_18500 ENOG4105KUS lysozyme VEGS12_18510 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 VEGS12_18520 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) VEGS12_18530 ENOG4108ES9 ParB domain protein nuclease VEGS12_18810 ENOG410685N tail fiber protein VEGS12_18820 ENOG4105UZW Tail fiber assembly protein VEGS12_18830 ENOG4105MN3 Resolvase VEGS12_18840 ENOG4105W3V DNA-binding, transcriptional regulator VEGS12_18850 ENOG4108RW8 Universal stress protein F VEGS12_18860 ENOG4105FCK Membrane VEGS12_18870 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) VEGS12_18880 ENOG4105IKK cytoplasmic protein VEGS12_18890 ENOG41090X5 Heat shock protein hslJ VEGS12_18900 ENOG4105C5I Dehydrogenase VEGS12_18910 ENOG4107H52 Dicarboxylate transport VEGS12_18920 ENOG410689M (LipO)protein VEGS12_18930 ENOG4105WXT Conserved Protein VEGS12_18940 ENOG4108WFR AraC Family Transcriptional Regulator VEGS12_18950 ENOG4105C26 Dehydrogenase VEGS12_18960 ENOG4105F11 amine oxidase VEGS12_18970 ENOG4105DXM phenylacetic acid degradation protein VEGS12_18980 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit VEGS12_18990 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit VEGS12_19000 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit VEGS12_19010 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit VEGS12_19020 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) VEGS12_19030 ENOG4105E39 Enoyl-CoA hydratase VEGS12_19040 ENOG4108UKI Enoyl-CoA hydratase VEGS12_19050 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase VEGS12_19060 ENOG4108ZJI phenylacetic acid degradation protein VEGS12_19070 ENOG4105CHU acetyl-coa acetyltransferase VEGS12_19080 ENOG4105DZS Phenylacetate-CoA ligase VEGS12_19090 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein VEGS12_19100 ENOG4108Z0R Transferase VEGS12_19110 ENOG4107S5I aldo keto reductase VEGS12_19140 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase VEGS12_19150 ENOG4108HPI phosphatidate Cytidylyltransferase VEGS12_19160 ENOG4105E8V Alpha Beta Hydrolase Fold protein VEGS12_19170 ENOG41077RS Phosphatase VEGS12_19190 ENOG4105CQ7 ATP-dependent helicase VEGS12_19200 ENOG4107DB1 DUF218 domain VEGS12_19210 ENOG4105C26 Dehydrogenase VEGS12_19220 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase VEGS12_19230 ENOG4105CPW cytochrome b561 VEGS12_19240 ENOG4105UPP uncharacterized protein ydcA VEGS12_19250 ENOG4107NK6 Hok/gef family VEGS12_19260 ENOG4105C8Q Methyl-accepting chemotaxis VEGS12_19270 ENOG4105DDW LysR family Transcriptional regulator VEGS12_19280 ENOG4105E32 cytoplasmic protein VEGS12_19300 ENOG4105Z2P Protein of unknown function (DUF465) VEGS12_19310 ENOG4108Z9I -acetyltransferase VEGS12_19320 ENOG4107WE3 acetyltransferase YdcK VEGS12_19330 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein VEGS12_19340 ENOG41088CC tellurite resistance protein tehB VEGS12_19350 ENOG4108KKZ (LipO)protein VEGS12_19360 ENOG4108RS6 transposase VEGS12_19370 ENOG4105D7V transposase VEGS12_19380 ENOG4105DKK Benzoate VEGS12_19390 ENOG4108JCI Transcriptional regulator VEGS12_19400 ENOG4105CFP Peptidase U32 VEGS12_19410 ENOG4105RR0 Protein of unknown function (DUF2554) VEGS12_19420 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin VEGS12_19430 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family VEGS12_19440 ENOG4107TYH extracellular solute-binding protein family 1 VEGS12_19450 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) VEGS12_19460 ENOG4105D81 ABC transporter, permease VEGS12_19470 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component VEGS12_19500 ENOG410654E Membrane VEGS12_19510 ENOG4105R71 cytoplasmic protein VEGS12_19520 ENOG4108T9Y Inner membrane protein ydcZ VEGS12_19530 ENOG4108Z7F N-acetyltransferase VEGS12_19540 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein VEGS12_19550 ENOG4108WYP Transcriptional regulator VEGS12_19560 ENOG4105CHB tonB-dependent Receptor VEGS12_19570 ENOG4108NS2 receptor VEGS12_19580 ENOG4105C85 amino acid VEGS12_19590 ENOG4108N27 Glutathione S-transferase VEGS12_19610 ENOG4105CS6 Rhs element vgr protein VEGS12_19620 ENOG4105CS6 Rhs element vgr protein VEGS12_19630 ENOG4105CNA YD repeat protein VEGS12_19650 ENOG410600T transposase VEGS12_19660 ENOG410600T transposase VEGS12_19690 ENOG4105CNA YD repeat protein VEGS12_19710 ENOG410600T transposase VEGS12_19730 ENOG4108MEJ flavin reductase domain protein VEGS12_19740 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase VEGS12_19750 ENOG4105JAB phenazine biosynthesis protein, phzf family VEGS12_19760 ENOG4105D0D Nitrate reductase 2, gamma subunit VEGS12_19770 ENOG4108NZN Respiratory nitrate reductase 2 delta chain VEGS12_19780 ENOG4108IUE nitrate reductase beta subunit VEGS12_19790 ENOG4105CRU nitrate reductase, alpha subunit VEGS12_19800 ENOG4107QND Nitrite extrusion protein VEGS12_19810 ENOG4108UI3 Leucine Rich repeat VEGS12_19830 ENOG4105RPH Inner membrane protein YddG VEGS12_19850 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein VEGS12_19860 ENOG4108MG3 formate dehydrogenase VEGS12_19870 ENOG41084S7 Plasmid maintenance system antidote protein VEGS12_19880 ENOG4105DQ4 alcohol dehydrogenase VEGS12_19900 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein VEGS12_19910 ENOG4105TPS biofilm-dependent modulation protein VEGS12_19920 ENOG4108Z9K Osmotically inducible protein VEGS12_19930 ENOG4105DTD Dehydrogenase VEGS12_19940 ENOG4105CY2 Citrate transporter VEGS12_19950 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase VEGS12_19960 ENOG4105CHU acetyl-coa acetyltransferase VEGS12_19970 ENOG4107QNJ CoA-transferase subunit B VEGS12_19980 ENOG4107QP7 CoA-transferase subunit A VEGS12_19990 ENOG4105DUM transcriptional regulator, lysR family VEGS12_20000 ENOG4107H6U ABC transporter VEGS12_20010 ENOG4105C3U ABC transporter VEGS12_20020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component VEGS12_20030 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component VEGS12_20040 ENOG4105DEF Extracellular solute-binding protein, family 5 VEGS12_20050 ENOG4108UQS dipeptidase VEGS12_20060 ENOG4105BZU Histidine kinase VEGS12_20080 ENOG4105F32 YngK protein VEGS12_20100 ENOG4105E5D amino acid VEGS12_20110 ENOG4105CVK Glutamate decarboxylase VEGS12_20120 ENOG4107RAN Peptidase, M16 VEGS12_20130 ENOG4105PE1 Receptor VEGS12_20140 ENOG4105CQ0 ABC transporter VEGS12_20150 ENOG4105C4X radical SAM domain protein VEGS12_20160 ENOG4105ENH Sulfatase VEGS12_20170 ENOG4105Z68 AraC Family Transcriptional Regulator VEGS12_20190 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit VEGS12_20200 ENOG4106PIH fimbrial-like protein ydeQ VEGS12_20210 ENOG4106318 fimbrial-like protein YdeR VEGS12_20220 ENOG4108WDE Fimbrial protein VEGS12_20230 ENOG4105CW0 outer membrane usher protein VEGS12_20250 ENOG4108RQP Major type 1 subunit fimbrin VEGS12_20260 ENOG4108MBK is1 orf2 VEGS12_20280 ENOG4108T58 Mg2 transport protein CorA VEGS12_20290 ENOG4107QUT magnesium and cobalt transport protein CorA VEGS12_20310 ENOG4108MBK is1 orf2 VEGS12_20320 ENOG4108T1W Fimbrial subunit type 3 VEGS12_20420 ENOG4108MBK is1 orf2 VEGS12_20430 ENOG4107QPD alcohol dehydrogenase VEGS12_20440 ENOG4105F2I Transposase VEGS12_20450 ENOG4108BUD transposase VEGS12_20480 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein VEGS12_20500 ENOG4105EQR Transposase IS116 IS110 IS902 VEGS12_20510 ENOG4105EQR Transposase IS116 IS110 IS902 VEGS12_20520 ENOG4105EQR Transposase IS116 IS110 IS902 VEGS12_20530 ENOG4105EQR Transposase IS116 IS110 IS902 VEGS12_20540 ENOG4105CMM transposase VEGS12_20680 ENOG4105CAF HipA N-terminal domain protein VEGS12_20690 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein VEGS12_20730 ENOG4105C2J ABC transporter VEGS12_20780 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound VEGS12_20800 ENOG4105FFC UPF0187 protein VEGS12_20820 ENOG4105BZU Histidine kinase VEGS12_20830 ENOG4105M0C cytoplasmic protein VEGS12_20840 ENOG4105CSV Glutaminase VEGS12_20850 ENOG4105C26 Dehydrogenase VEGS12_20860 ENOG4105EGI Transcriptional regulator VEGS12_20910 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes VEGS12_20920 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF VEGS12_20930 ENOG4106DNR multiple antibiotic resistance protein VEGS12_20940 ENOG4105CS2 ec 3.2.1.21 VEGS12_20960 ENOG4105VCP PTS System VEGS12_20970 ENOG4105CK1 PTS System VEGS12_20990 ENOG4105FDP GntR family transcriptional regulator VEGS12_21000 ENOG4108594 Permease of the drug metabolite transporter VEGS12_21010 ENOG4105E5W Transporter VEGS12_21020 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria VEGS12_21030 ENOG4108YDI single-species biofilm formation on inanimate substrate VEGS12_21040 ENOG4108WTK competence damage-inducible protein VEGS12_21050 ENOG4105DGW oligopeptidase A VEGS12_21060 ENOG4105EMU Dehydrogenase VEGS12_21070 ENOG4107XBN GntR Family Transcriptional Regulator VEGS12_21080 ENOG41061EV selenium-binding protein YdfZ VEGS12_21090 ENOG4105DEI Mannitol dehydrogenase VEGS12_21120 ENOG4105UZW Tail fiber assembly protein VEGS12_21130 ENOG4108X9F tail fiber protein VEGS12_21310 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) VEGS12_21420 ENOG4105QFS Lysis protein S homolog from lambdoid prophage VEGS12_21430 ENOG4105HGD Antitermination protein VEGS12_21440 ENOG4105KSK (crossover) junction endodeoxyribonuclease VEGS12_21450 ENOG4108MXB Protein of unknown function (DUF968) VEGS12_21570 ENOG41087BU transcriptional repressor DicA VEGS12_21610 ENOG4106G8A Qin prophage VEGS12_21640 ENOG4107R08 Integrase VEGS12_21650 ENOG4105CPQ Dehydrogenase VEGS12_21660 ENOG4105CXK mandelate racemase muconate lactonizing VEGS12_21700 ENOG4108MK9 spermidine N(1)-acetyltransferase VEGS12_21710 ENOG4105D69 UPF0257 lipoprotein ynfC VEGS12_21720 ENOG4105KBG Protein of unknown function (DUF1161) VEGS12_21730 ENOG4107QY8 reductase VEGS12_21820 ENOG4107QY8 reductase VEGS12_21830 ENOG4105C3J Cysteine desulfurase VEGS12_21840 ENOG4105QAX Iron-sulfur VEGS12_21850 ENOG4107KGK dmso reductase anchor subunit VEGS12_21860 ENOG4108NEM leader-binding protein dmsD VEGS12_21880 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) VEGS12_21890 ENOG4105DAG ROK family VEGS12_21900 ENOG4106NZI LysR family Transcriptional regulator VEGS12_21910 ENOG4105D94 Major Facilitator Superfamily VEGS12_21930 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap VEGS12_21960 ENOG4105DSF transport protein VEGS12_21970 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) VEGS12_21980 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) VEGS12_21990 ENOG4105C5D exported protein VEGS12_22000 ENOG4105D5Q Arginine ornithine antiporter VEGS12_22020 ENOG4105RA2 Membrane VEGS12_22030 ENOG4107EXC regulatoR VEGS12_22040 ENOG4105JJR Histidine kinase VEGS12_22060 ENOG4105C9Q fumarate hydratase class II VEGS12_22070 ENOG4107GFK fumarate VEGS12_22080 ENOG4105EIP mannose-6-phosphate isomerase VEGS12_22090 ENOG4106J39 exported protein VEGS12_22100 ENOG4108QNI outer membrane porin protein VEGS12_22110 ENOG4105CT4 transporter VEGS12_22120 ENOG4105CNT hydrolase family 2 VEGS12_22130 ENOG4105XEA Tetr family transcriptional regulator VEGS12_22140 ENOG4107ZQV short-chain dehydrogenase reductase VEGS12_22150 ENOG4107P2S Transcriptional regulator VEGS12_22160 ENOG4105CI1 PTS System VEGS12_22170 ENOG4105C87 Aminotransferase class I and II VEGS12_22190 ENOG4105D9R oxidoreductase VEGS12_22200 ENOG4106C6R beta-lactam resistance protein VEGS12_22210 ENOG4105QZ5 OriC-binding nucleoid-associated protein VEGS12_22220 ENOG4105M9B inner membrane protein ydgK VEGS12_22270 ENOG4108UQQ Electron transport complex VEGS12_22290 ENOG4105CSM endonuclease III VEGS12_22300 ENOG4105DUX Transporter VEGS12_22310 ENOG4108K3A Glutathione S-transferase VEGS12_22320 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) VEGS12_22350 ENOG410642K Lysozyme inhibitor VEGS12_22370 ENOG4108XTF Outer Membrane Lipoprotein VEGS12_22400 ENOG4105Y49 secretion protein, HlyD family VEGS12_22410 ENOG4105DSW Fusaric acid resistance protein VEGS12_22420 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) VEGS12_22430 ENOG4107RGM aldo keto reductase VEGS12_22440 ENOG4105F9F transposase VEGS12_22450 ENOG4108WUH Transcriptional regulator, TetR family VEGS12_22460 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase VEGS12_22470 ENOG4108UYE Lactoylglutathione lyase VEGS12_22490 ENOG4107QRT dEAD DEAH box helicase VEGS12_22500 ENOG4105M2J Glutaredoxin VEGS12_22510 ENOG4105K4H Nlp p60 protein VEGS12_22520 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) VEGS12_22530 ENOG4105F27 Major Facilitator VEGS12_22550 ENOG4105F52 Transcriptional regulator VEGS12_22560 ENOG4105CZQ inner membrane transport protein YdhC VEGS12_22570 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase VEGS12_22580 ENOG4108R6K riboflavin synthase, subunit alpha VEGS12_22610 ENOG4105N0V mono-oxygenase ydhR VEGS12_22620 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain VEGS12_22630 ENOG4108Y7C Conserved Protein VEGS12_22640 ENOG4108NWD Cytochrome VEGS12_22650 ENOG4108393 oxidoreductase Fe-S subunit VEGS12_22660 ENOG4105JVW VEGS12_22670 ENOG4105WE2 aldehyde ferredoxin oxidoreductase VEGS12_22680 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein VEGS12_22690 ENOG4105RFR Protein of unknown function (DUF2767) VEGS12_22700 ENOG4105CA9 Pyruvate kinase VEGS12_22710 ENOG4105KMX major outer membrane lipoprotein VEGS12_22720 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein VEGS12_22750 ENOG4105JRK feS assembly protein SufD VEGS12_22760 ENOG4105C3K feS assembly ATPase SufC VEGS12_22770 ENOG4105DIW FeS assembly protein SUFB VEGS12_22780 ENOG4108Z4V iron-sulfur cluster assembly VEGS12_22790 ENOG410671Z uncharacterized protein ydiH VEGS12_22800 ENOG4105KA0 thioesterase Superfamily protein VEGS12_22810 ENOG4105CQB FAD linked oxidase domain protein VEGS12_22820 ENOG4105IPI Membrane VEGS12_22830 ENOG4105SUA Ydil protein VEGS12_22840 ENOG4105EMV Major Facilitator VEGS12_22850 ENOG4105EMV Major Facilitator VEGS12_22880 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) VEGS12_22890 ENOG4105C1G acyl-Coa dehydrogenase VEGS12_22900 ENOG4105W4W Transcriptional regulator VEGS12_22910 ENOG4105CV7 Electron transfer flavoprotein VEGS12_22920 ENOG4105C10 Electron transfer flavoprotein VEGS12_22930 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase VEGS12_22940 ENOG41090P5 ferredoxin-like protein VEGS12_22950 ENOG4105CEY Amp-dependent synthetase and ligase VEGS12_22960 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) VEGS12_22980 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) VEGS12_23010 ENOG4108TC0 Diguanylate phosphodiesterase VEGS12_23020 ENOG4108QBX (LipO)protein VEGS12_23040 ENOG4108V06 Glutathione peroxidase VEGS12_23100 ENOG41082NX 50s ribosomal protein l35 VEGS12_23110 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) VEGS12_23150 ENOG4108NE3 Salt-induced outer membrane protein VEGS12_23160 ENOG4105DE4 1-phosphofructokinase VEGS12_23170 ENOG4105P10 Uncharacterized protein ydiZ VEGS12_23190 ENOG4107PN8 YfeABCD locus regulator VEGS12_23200 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 VEGS12_23210 ENOG4107K5X Membrane-bound metal-dependent hydrolase VEGS12_23220 ENOG4108ETY sodium dicarboxylate symporter VEGS12_23260 ENOG4105CH6 catalase VEGS12_23280 ENOG4105F8D glycoside hydrolase family 4 VEGS12_23290 ENOG4105EZV Transcriptional regulator VEGS12_23300 ENOG4105VCP PTS System VEGS12_23310 ENOG4105CK1 PTS System VEGS12_23320 ENOG4105VZJ PTS System VEGS12_23330 ENOG4105KKI DNA-binding transcriptional activator OsmE VEGS12_23350 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) VEGS12_23370 ENOG4108SPG Periplasmic Protein VEGS12_23430 ENOG4105CGK Exodeoxyribonuclease III VEGS12_23440 ENOG4108RSN SNARE associated Golgi VEGS12_23450 ENOG4108KCW iron-sulfur cluster binding VEGS12_23460 ENOG4108N5C SNARE associated Golgi protein-related protein VEGS12_23470 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) VEGS12_23480 ENOG4105VNH ABC transporter solute-binding protein VEGS12_23490 ENOG4105CXZ ABC transporter, permease VEGS12_23500 ENOG4108VGW abc transporter atp-binding protein VEGS12_23510 ENOG4107RM6 sulfurtransferase VEGS12_23520 ENOG4108T9J Cdp-alcohol phosphatidyltransferase VEGS12_23530 ENOG4105M6F mutator MutT protein VEGS12_23540 ENOG4105MTM Protein of unknown function (DUF1496) VEGS12_23550 ENOG4105D82 Glutamate dehydrogenase VEGS12_23570 ENOG41065FB inner membrane protein ynji VEGS12_23580 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) VEGS12_23600 ENOG41069NU Nitroreductase VEGS12_23610 ENOG4105D07 Signal peptide peptidase, SppA VEGS12_23620 ENOG4105HDK L-asparaginase VEGS12_23630 ENOG4108RWI nicotinamidase VEGS12_23640 ENOG4108KUU Inner membrane metabolite transport protein ydjE VEGS12_23650 ENOG4105E98 transcriptional regulator DeoR family VEGS12_23660 ENOG4105CPC Aldo Keto reductase VEGS12_23670 ENOG4107UH8 sugar kinase VEGS12_23680 ENOG4105D2N Aldolase VEGS12_23690 ENOG4105CPQ Dehydrogenase VEGS12_23700 ENOG4107TE1 transport protein VEGS12_23710 ENOG4105CPQ Dehydrogenase VEGS12_23720 ENOG4105VUT cytoplasmic protein VEGS12_23740 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase VEGS12_23750 ENOG4105DSB aldose 1-epimerase VEGS12_23760 ENOG4105CV8 reductase VEGS12_23770 ENOG4105GNX MltA-interacting MipA family protein VEGS12_23780 ENOG4105CYN Serine protein kinase VEGS12_23800 ENOG4106KTS Inner membrane protein yeaI VEGS12_23810 ENOG4108KHP Diguanylate cyclase VEGS12_23820 ENOG4108KXH Ybak prolyl-tRNA synthetase associated VEGS12_23840 ENOG4105R1U AraC Family Transcriptional Regulator VEGS12_23850 ENOG4105DJ2 Major Facilitator Superfamily VEGS12_23860 ENOG4105K78 MarR family Transcriptional regulator VEGS12_23870 ENOG4105UCG Domain of unknown function (DUF333) VEGS12_23880 ENOG410620I Diguanylate cyclase VEGS12_23890 ENOG4105Y3U Transglycosylase-associated protein VEGS12_23900 ENOG4105D7V transposase VEGS12_23910 ENOG4105YP6 Domain of unknown function (DUF1869) VEGS12_23920 ENOG4108YS1 cytoplasmic protein VEGS12_23940 ENOG4105EJC lysr family transcriptional regulator VEGS12_23950 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) VEGS12_23960 ENOG4105C94 Transporter VEGS12_23970 ENOG4105DVW rieske (2Fe-2S) VEGS12_23980 ENOG4105E3J oxidoreductase VEGS12_23990 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) VEGS12_24000 ENOG4105CEY Amp-dependent synthetase and ligase VEGS12_24010 ENOG4105Y4Z Outer Membrane Lipoprotein VEGS12_24020 ENOG41072GX Peptidase M22 Glycoprotease VEGS12_24030 ENOG4105DVT helicase VEGS12_24040 ENOG4105M4H endoribonuclease L-psp VEGS12_24050 ENOG4105V2F Uncharacterized protein yoac VEGS12_24070 ENOG4105CRQ synthase (Component I) VEGS12_24090 ENOG4105EJQ L-serine dehydratase VEGS12_24100 ENOG4107XTP (EAL) domain protein VEGS12_24110 ENOG4105EE5 Membrane protein terC VEGS12_24120 ENOG4105DAS pts system VEGS12_24130 ENOG4105ETZ PTS System VEGS12_24140 ENOG4105F3R pts system mannose fructose sorbose family iid VEGS12_24170 ENOG4105DHI Methyltransferase VEGS12_24190 ENOG4105Q3Y exported protein VEGS12_24200 ENOG4105TIK VEGS12_24210 ENOG4105J4Q Transcriptional regulator VEGS12_24220 ENOG4105C0R drug resistance transporter emrb qaca subfamily VEGS12_24240 ENOG4105CN1 protease VEGS12_24260 ENOG4108ZGC gaf domain protein VEGS12_24270 ENOG4105H2K paraquat-inducible protein a VEGS12_24280 ENOG4105DY2 Paraquat-inducible protein b VEGS12_24300 ENOG4105WT8 Protein of unknown function (DUF1480) VEGS12_24310 ENOG4105UVW uncharacterized protein yebW VEGS12_24320 ENOG4108R1E Serine threonine protein phosphatase 1 VEGS12_24330 ENOG4105NKT exported protein VEGS12_24340 ENOG4108PNC copper resistance VEGS12_24350 ENOG4105FXM Copper resistance protein VEGS12_24360 ENOG4105MPK DNA polymerase III subunit theta VEGS12_24370 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase VEGS12_24380 ENOG4105UMD exodeoxyribonuclease X VEGS12_24390 ENOG4105CUG Oligopeptidase b VEGS12_24400 ENOG4108Q2J Inner membrane protein YebE VEGS12_24420 ENOG4105X2V dna damage-inducible protein VEGS12_24440 ENOG4108UHU Aldolase VEGS12_24450 ENOG4105C01 Dihydroxy-acid dehydratase VEGS12_24460 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase VEGS12_24480 ENOG4106KNT transcriptional regulator VEGS12_24490 ENOG4105CA9 Pyruvate kinase VEGS12_24500 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase VEGS12_24510 ENOG4105DR5 peptidase VEGS12_24520 ENOG4105NXV High-affinity zinc uptake system protein VEGS12_24540 ENOG4105FAV ABC, transporter VEGS12_24570 ENOG4107S01 Repressor protein MetJ VEGS12_24590 ENOG4105CDY transcriptional regulatory protein VEGS12_24600 ENOG4108TIT dATP pyrophosphohydrolase VEGS12_24620 ENOG4105D3W isochorismatase VEGS12_24630 ENOG41081XQ Conserved Protein VEGS12_24640 ENOG4105WJG Glutathione VEGS12_24670 ENOG4107QY8 reductase VEGS12_24680 ENOG4105CUW cytochrome C-TYPE protein VEGS12_24700 ENOG4106ZCM YecM protein VEGS12_24710 ENOG4105C75 arginyL-tRNA synthetase VEGS12_24730 ENOG4105W13 flagellar protein VEGS12_24740 ENOG4105D7B Flagellar biosynthesis protein flha VEGS12_24750 ENOG4105D00 flagellar biosynthetic protein flhB VEGS12_24760 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) VEGS12_24770 ENOG4108VYJ response regulator receiver protein VEGS12_24780 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) VEGS12_24790 ENOG4105BZU Histidine kinase VEGS12_24800 ENOG4105C8Q Methyl-accepting chemotaxis VEGS12_24810 ENOG4105C8Q Methyl-accepting chemotaxis VEGS12_24820 ENOG4108V3W Chemotaxis protein, CheW VEGS12_24830 ENOG4105CBS Chea signal transduction histidine kinase VEGS12_24840 ENOG4105ER2 Ompa motb domain protein VEGS12_24850 ENOG4107RD7 Flagellar Motor Protein, MotA VEGS12_24860 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region VEGS12_24880 ENOG4108VA4 Universal stress protein VEGS12_24900 ENOG4108K4C ec 3.1.3.12 VEGS12_24910 ENOG4105CNN ABC, transporter VEGS12_24920 ENOG4105C2J ABC transporter VEGS12_24930 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator VEGS12_24940 ENOG4108UEC Ferritin-like protein VEGS12_24950 ENOG4105N4N Protein of unknown function (DUF2766) VEGS12_24970 ENOG41090A1 ferritin VEGS12_24980 ENOG4105VVZ metal-binding protein VEGS12_24990 ENOG4105E0U tyrosine-specific transport protein VEGS12_25000 ENOG4106RHG Yeca family VEGS12_25030 ENOG4105WH1 Two component transcriptional regulator luxr family VEGS12_25040 ENOG4105XVG cytoplasmic protein VEGS12_25050 ENOG4105VJY transcriptional regulator VEGS12_25060 ENOG4105CDA abc transporter atp-binding protein VEGS12_25070 ENOG4105E5Q amino acid AbC transporter VEGS12_25090 ENOG4105EAB amino acid AbC transporter VEGS12_25100 ENOG4108M9K flagella biosynthesis protein FliZ VEGS12_25110 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) VEGS12_25120 ENOG4105I03 Flagellin VEGS12_25130 ENOG4105DTS flagellar hook-associated VEGS12_25140 ENOG4105MQ3 flagellar protein FliS VEGS12_25160 ENOG4105E5K Alpha-amylase VEGS12_25170 ENOG4108W9D (LipO)protein VEGS12_25180 ENOG41066VF YeeE YedE family protein VEGS12_25200 ENOG4108RAV Conserved protein VEGS12_25220 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) VEGS12_25230 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) VEGS12_25240 ENOG41090PJ Flagellar assembly protein VEGS12_25250 ENOG4108JIR Flagellum-specific ATP synthase VEGS12_25260 ENOG4105GSA Flagellar export protein flij VEGS12_25270 ENOG4105WF4 Flagellar hook-length control protein VEGS12_25280 ENOG4107ZI8 flagellar basal body-associated protein flil VEGS12_25290 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) VEGS12_25300 ENOG4105DD5 Flagellar motor switch protein VEGS12_25310 ENOG4105K0P flagellar biosynthesis protein VEGS12_25320 ENOG4105CN7 Flagellar biosynthetic protein FliP VEGS12_25340 ENOG4105D19 Role in flagellar biosynthesis (By similarity) VEGS12_25350 ENOG4107TKS colanic acid capsular biosynthesis activation protein A VEGS12_25370 ENOG4105YX3 cellular response to acidity VEGS12_25390 ENOG4105BZU Histidine kinase VEGS12_25400 ENOG4105VNZ cytoplasmic protein VEGS12_25410 ENOG4105CKW Inner membrane protein yedI VEGS12_25420 ENOG4105FDR Membrane VEGS12_25430 ENOG41090BB DNA mismatch endonuclease (vsr) VEGS12_25440 ENOG4105DVF Cytosine-specific methyltransferase VEGS12_25450 ENOG4105EST Metal Dependent Phosphohydrolase VEGS12_25460 ENOG4105Y0K Inner membrane protein YedR VEGS12_25470 ENOG4105FCK Membrane VEGS12_25490 ENOG4107ZY3 Histidine kinase VEGS12_25500 ENOG4105CK6 Two component transcriptional regulator (Winged helix family VEGS12_25510 ENOG4105VT2 5-hydroxyisourate hydrolase VEGS12_25540 ENOG4108MEK Metal-binding protein YodA VEGS12_25550 ENOG4108VKM cytochrome b561 VEGS12_25570 ENOG4105TNG K13735 adhesin invasin VEGS12_25610 ENOG4105CSH Transporter VEGS12_25620 ENOG4105FYV Amp nucleosidase VEGS12_25630 ENOG4105CDY transcriptional regulatory protein VEGS12_25640 ENOG4105UQX Mate efflux family protein VEGS12_25650 ENOG4107R11 Transcriptional regulator VEGS12_25660 ENOG4106P55 Transcriptional regulator VEGS12_25670 ENOG4108PXI ErfK YbiS YcfS YnhG VEGS12_25700 ENOG4108YZT Adenosylcobinamide kinase VEGS12_25730 ENOG4105DR8 Membrane VEGS12_25750 ENOG4105DZ1 carboxypeptidase VEGS12_25760 ENOG4105CJB Exodeoxyribonuclease I VEGS12_25780 ENOG4105CUC YeeE YedE family protein VEGS12_25790 ENOG4105CUB amino acid VEGS12_25800 ENOG4105EQ1 Transcriptional regulator VEGS12_25810 ENOG4107SRH Nad-dependent epimerase dehydratase VEGS12_25820 ENOG4105KRQ Addiction module toxin, Txe YoeB family VEGS12_25830 ENOG4105VTW prevent-host-death family VEGS12_25850 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) VEGS12_25860 ENOG4105CIH Imidazole acetol-phosphate transaminase VEGS12_25870 ENOG4105ECC imidazole-glycerol-phosphate dehydratase VEGS12_25880 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) VEGS12_25920 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) VEGS12_25930 ENOG4105C6Y Udp-glucose 6-dehydrogenase VEGS12_25940 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) VEGS12_26000 ENOG4105C3Q Glycosyl transferase, family 2 VEGS12_26020 ENOG4108RYC glycosyltransferase VEGS12_26030 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase VEGS12_26040 ENOG4105DMT epimerase dehydratase VEGS12_26050 ENOG4105G1A colanic acid biosynthesis protein VEGS12_26060 ENOG4107T8Q Glycosyl transferase (Group 1 VEGS12_26070 ENOG4105C74 pyruvyl transferase VEGS12_26080 ENOG4105PSV Polysaccharide Biosynthesis Protein VEGS12_26090 ENOG4105D3Q Sugar transferase VEGS12_26100 ENOG4107QKV phosphomannomutase VEGS12_26110 ENOG4105CJT Mannose-1-phosphate guanylyltransferase VEGS12_26120 ENOG4106CD9 glycosyl transferase group 1 VEGS12_26130 ENOG4105FGF GDP-mannose mannosyl hydrolase VEGS12_26140 ENOG4105C30 Nad-dependent epimerase dehydratase VEGS12_26150 ENOG4105C0K Gdp-mannose 4,6-dehydratase VEGS12_26160 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF VEGS12_26170 ENOG4105ECJ Glycosyl Transferase VEGS12_26180 ENOG4108NYJ Colanic acid VEGS12_26190 ENOG4107RXY Glycosyl transferase VEGS12_26200 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB VEGS12_26210 ENOG41090RK glycosyl transferase VEGS12_26220 ENOG4105D75 Capsular exopolysaccharide family VEGS12_26230 ENOG4105KJF protein tyrosine phosphatase VEGS12_26240 ENOG4105DAY polysaccharide export protein VEGS12_26260 ENOG4105EE5 Membrane protein terC VEGS12_26270 ENOG4108GAE asmA family VEGS12_26290 ENOG4105DBI uridine monophosphokinase VEGS12_26300 ENOG4105BZU Histidine kinase VEGS12_26310 ENOG4105D03 DNA-3-methyladenine glycosylase II VEGS12_26320 ENOG4105R8A Heat shock protein VEGS12_26330 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding VEGS12_26340 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase VEGS12_26350 ENOG4108M24 von Willebrand factor, type A VEGS12_26400 ENOG4105EB3 Histidine kinase VEGS12_26410 ENOG4105E3W Two component transcriptional regulator (Winged helix family VEGS12_26420 ENOG4105KWI UPF0339 protein VEGS12_26430 ENOG4105X54 addiction module antidote protein VEGS12_26450 ENOG4105CFP Peptidase U32 VEGS12_26460 ENOG41076Z6 Uncharacterized protein yegR VEGS12_26490 ENOG4107WTH Galactitol-1-phosphate dehydrogenase VEGS12_26500 ENOG4105DT3 PTS system, galactitol-specific IIc component VEGS12_26510 ENOG41090UW PTS System VEGS12_26520 ENOG41082GB PTS system galactitol-specific transporter subunit IIA VEGS12_26550 ENOG4105EIE fructose-bisphosphate aldolase VEGS12_26560 ENOG4105EAA nucleoside VEGS12_26570 ENOG4108KD5 ADP-ribosylation crystallin J1 VEGS12_26580 ENOG4108TFM Kinase, PfkB family VEGS12_26590 ENOG4105FDP GntR family transcriptional regulator VEGS12_26600 ENOG4108UQ1 hydrolase, family 25 VEGS12_26610 ENOG4105DWF phosphomethylpyrimidine kinase VEGS12_26650 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly VEGS12_26660 ENOG410662B Type-1 fimbrial protein VEGS12_26670 ENOG4105CW0 outer membrane usher protein VEGS12_26700 ENOG4105CW0 outer membrane usher protein VEGS12_26710 ENOG4108MQF Chaperone VEGS12_26720 ENOG41063W2 Fimbrial protein VEGS12_26730 ENOG41067AK Protein of unknown function (DUF2574) VEGS12_26740 ENOG4105D1F ATP-binding protein VEGS12_26760 ENOG4108KDT Molybdate metabolism regulator VEGS12_26770 ENOG4108KDT Molybdate metabolism regulator VEGS12_26790 ENOG4105KKX ATPase associated with various cellular activities aaa_5 VEGS12_26800 ENOG4105RD5 VEGS12_26810 ENOG4105DEG Vwa containing coxe family protein VEGS12_26820 ENOG410903U zinc ion binding VEGS12_26830 ENOG4108YCW (LipO)protein VEGS12_26840 ENOG4108W15 Protein of unknown function (DUF1456) VEGS12_26850 ENOG4108NEV two component transcriptional regulator, LytTR family VEGS12_26860 ENOG4108HRK Histidine kinase VEGS12_26870 ENOG4108XDN Transcriptional regulator VEGS12_26880 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component VEGS12_26890 ENOG4108IJ8 ABC transporter VEGS12_26900 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component VEGS12_26910 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system VEGS12_26920 ENOG4107QK4 glycoside hydrolase, family 3 domain protein VEGS12_26930 ENOG4105CXG d-lactate dehydrogenase VEGS12_26940 ENOG41061WM D-Alanyl-D-Alanine VEGS12_26950 ENOG41069YE inner membrane protein yohC VEGS12_26960 ENOG4105KHU inner membrane protein YohD VEGS12_26970 ENOG4105H9W Short-chain dehydrogenase reductase Sdr VEGS12_26980 ENOG4105ETP RND efflux system, outer membrane lipoprotein VEGS12_26990 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) VEGS12_27010 ENOG41067MG lrgb family VEGS12_27030 ENOG4107GZ4 SanA protein VEGS12_27040 ENOG4105Y9N Membrane VEGS12_27050 ENOG4105BZ8 glutamate synthase VEGS12_27060 ENOG4107SJI Dehydrogenase VEGS12_27070 ENOG4108HWV )-transporter VEGS12_27080 ENOG4105C2J ABC transporter VEGS12_27090 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator VEGS12_27100 ENOG41060NJ transcriptional regulator VEGS12_27120 ENOG4105DHF Membrane VEGS12_27150 ENOG4105D05 Receptor VEGS12_27160 ENOG4108IQI permease VEGS12_27170 ENOG4105DUM transcriptional regulator, lysR family VEGS12_27180 ENOG4105HMI Membrane VEGS12_27200 ENOG4105DD7 kinase (PfkB family VEGS12_27210 ENOG4105D9N nucleoside VEGS12_27230 ENOG4108Y4K DNA-binding transcriptional activator VEGS12_27240 ENOG4105D9N nucleoside VEGS12_27250 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) VEGS12_27270 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) VEGS12_27280 ENOG4105DD7 kinase (PfkB family VEGS12_27290 ENOG4105DM4 PTS System VEGS12_27300 ENOG4105DE4 1-phosphofructokinase VEGS12_27310 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein VEGS12_27320 ENOG4105S8Q sugar efflux transporter VEGS12_27330 ENOG4105KRS Proteinase inhibitor VEGS12_27350 ENOG4105DEI Mannitol dehydrogenase VEGS12_27360 ENOG4105CKI cobalamin synthesis protein VEGS12_27370 ENOG41076MN Phosphoesterase, PA-phosphatase related VEGS12_27380 ENOG4107TT5 NLP P60 protein VEGS12_27390 ENOG4105CXC rtn protein VEGS12_27400 ENOG4105E43 Extracellular solute-binding protein, family 5 VEGS12_27410 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component VEGS12_27420 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component VEGS12_27430 ENOG4108JQ5 ABC transporter VEGS12_27440 ENOG4105HG6 VEGS12_27450 ENOG4105C2C drug resistance transporter, Bcr CflA VEGS12_27460 ENOG4105I08 Pseudouridine synthase VEGS12_27470 ENOG4105CFI type iii restriction protein res subunit VEGS12_27510 ENOG4105E68 Sulfatase VEGS12_27520 ENOG4108MGN ATP-binding component of a transport system VEGS12_27530 ENOG4108MGN ATP-binding component of a transport system VEGS12_27540 ENOG4105WH1 Two component transcriptional regulator luxr family VEGS12_27550 ENOG4105KWW Biogenesis protein VEGS12_27560 ENOG4107QX9 Thiol disulfide interChange protein VEGS12_27570 ENOG4105DA4 cytochrome c-type biogenesis protein VEGS12_27590 ENOG4105X3C heme exporter protein VEGS12_27600 ENOG41060IM Heme exporter protein VEGS12_27610 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) VEGS12_27630 ENOG4105CUW cytochrome C-TYPE protein VEGS12_27640 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) VEGS12_27650 ENOG4105GXZ Ferredoxin-type protein NapH VEGS12_27660 ENOG4108BGM Quinol dehydrogenase periplasmic component VEGS12_27680 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase VEGS12_27710 ENOG4105IBP Cyclic peptide transporter VEGS12_27720 ENOG4105CF1 Alkylated DNA repair protein VEGS12_27730 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) VEGS12_27750 ENOG4105CJ2 (LipO)protein VEGS12_27760 ENOG4105FCK Membrane VEGS12_27770 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC VEGS12_27780 ENOG41068CG regulatoR VEGS12_27790 ENOG4105BZU Histidine kinase VEGS12_27800 ENOG4105EDV vault protein VEGS12_27810 ENOG41081SK signal peptide protein VEGS12_27820 ENOG4107S52 alpha-2-macroglobulin domain protein VEGS12_27830 ENOG4108QJJ Protein of unknown function (DUF1175) VEGS12_27840 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) VEGS12_27850 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) VEGS12_27860 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) VEGS12_27880 ENOG4107GHC outer membrane autotransporter VEGS12_27890 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) VEGS12_27900 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) VEGS12_27910 ENOG4105XPH Ferredoxin VEGS12_27920 ENOG4105FQR PH-inducible protein involved in stress response VEGS12_27930 ENOG4107R11 Transcriptional regulator VEGS12_27940 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase VEGS12_27950 ENOG4105CXY transporter VEGS12_27970 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A VEGS12_27990 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) VEGS12_28000 ENOG4105DNE Transposase VEGS12_28030 ENOG4108UII YfaZ family VEGS12_28130 ENOG4106GZG polymyxin resistance protein B VEGS12_28140 ENOG4105CEY Amp-dependent synthetase and ligase VEGS12_28160 ENOG4108IPT Naphthoate synthase VEGS12_28190 ENOG4105E4F Isochorismate synthase VEGS12_28200 ENOG4105TNS Conserved Protein VEGS12_28210 ENOG4107YB6 acetyltransferase, (GNAT) family VEGS12_28240 ENOG4107VAM peptidase, m28 VEGS12_28250 ENOG4105GDX Domain of unknown function (DUF1877) VEGS12_28270 ENOG4105C8S subunit m VEGS12_28280 ENOG4105D65 subunit l VEGS12_28300 ENOG4107UFS subunit j VEGS12_28330 ENOG4108IEH NADH dehydrogenase subunit g VEGS12_28340 ENOG4107QIZ NADH dehydrogenase VEGS12_28350 ENOG4105GKE subunit e VEGS12_28390 ENOG4107NQ8 LysR family Transcriptional regulator VEGS12_28400 ENOG4105CHM Aminotransferase VEGS12_28420 ENOG4107QWE )-transporter VEGS12_28430 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 VEGS12_28440 ENOG4105XWI UPF0304 protein VEGS12_28460 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) VEGS12_28470 ENOG4105C6K Malic enzyme VEGS12_28480 ENOG4105CSX c4-dicarboxylate anaerobic carrier VEGS12_28490 ENOG4105PTV Nudix Hydrolase VEGS12_28500 ENOG4108RE9 Phosphodiesterase VEGS12_28510 ENOG4108SHQ Glutathione S-transferase VEGS12_28520 ENOG4105CYM Glutathione S-transferase VEGS12_28530 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase VEGS12_28540 ENOG4105ECP epimerase VEGS12_28550 ENOG4105DNE Transposase VEGS12_28560 ENOG4108JEH abc transporter atp-binding protein VEGS12_28570 ENOG4106YG3 ABC transporter VEGS12_28580 ENOG4105DSP amino acid AbC transporter VEGS12_28590 ENOG4105E89 ABC transporter VEGS12_28600 ENOG4105E89 ABC transporter VEGS12_28610 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase VEGS12_28620 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase VEGS12_28630 ENOG4105E96 Colicin v production protein VEGS12_28640 ENOG4108S3P Sporulation domain protein VEGS12_28650 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase VEGS12_28670 ENOG4105DQR SNARE associated Golgi VEGS12_28690 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) VEGS12_28710 ENOG4106WZ1 flagella biosynthesis regulator VEGS12_28720 ENOG4105F9N Major Facilitator Superfamily VEGS12_28730 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) VEGS12_28740 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) VEGS12_28750 ENOG4105MH2 YfcL protein VEGS12_28760 ENOG4108BPE -transporting atpase VEGS12_28770 ENOG4105EJ9 Membrane VEGS12_28790 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase VEGS12_28800 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) VEGS12_28840 ENOG4105US4 fimbrial-like protein yfcP VEGS12_28850 ENOG4105UGQ Fimbrial VEGS12_28860 ENOG4105NEV Fimbrial VEGS12_28870 ENOG4108FZ9 Chaperone VEGS12_28880 ENOG4106PG1 outer membrane usher protein VEGS12_28900 ENOG4108BY2 phosphohistidine phosphatase VEGS12_28930 ENOG4105KZW UPF0381 protein VEGS12_28940 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation VEGS12_28960 ENOG410903C (LipO)protein VEGS12_28970 ENOG4105S64 Formate nitrite transporter VEGS12_28980 ENOG4105DFP Integrase VEGS12_29130 ENOG4108N0N Phage Terminase Large Subunit VEGS12_29170 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 VEGS12_29210 ENOG4108R1E Serine threonine protein phosphatase 1 VEGS12_29260 ENOG4105NY2 NinB protein VEGS12_29310 ENOG4105CDU Replicative dna helicase VEGS12_29440 ENOG4105VIZ double-strand break repair protein VEGS12_29450 ENOG4108UUM single-stranded DNA-binding protein VEGS12_29480 ENOG41077V0 CPS-53 (KpLE1) prophage VEGS12_29530 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) VEGS12_29540 ENOG4105D7K pfkb domain protein VEGS12_29550 ENOG4108HKT sucrose-6-phosphate hydrolase VEGS12_29560 ENOG4106NDP Transcriptional regulator VEGS12_29570 ENOG4105C6Z Gluconate VEGS12_29590 ENOG4105C0R drug resistance transporter emrb qaca subfamily VEGS12_29600 ENOG4105CW7 secretion protein, HlyD family VEGS12_29610 ENOG4108WQH regulatoR VEGS12_29620 ENOG4105BZU Histidine kinase VEGS12_29630 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F VEGS12_29640 ENOG4108N2Y auxin Efflux VEGS12_29650 ENOG4105F9F transposase VEGS12_29680 ENOG4105F9F transposase VEGS12_29690 ENOG4105CFN oxalyl-CoA decarboxylase VEGS12_29710 ENOG4108V08 YfdX protein VEGS12_29730 ENOG4105W9M Membrane VEGS12_29740 ENOG4105D1S lipid A biosynthesis VEGS12_29750 ENOG4105CHM Aminotransferase VEGS12_29760 ENOG4108HRK Histidine kinase VEGS12_29770 ENOG4105DY9 regulatoR VEGS12_29780 ENOG4108CIP transcriptional regulator VEGS12_29790 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) VEGS12_29800 ENOG4105CN9 Peptidase m42 family protein VEGS12_29810 ENOG4105DC7 peptidase M24 VEGS12_29820 ENOG410863U PTS System VEGS12_29830 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) VEGS12_29860 ENOG4109076 Conserved Protein VEGS12_29880 ENOG4105D9N nucleoside VEGS12_29890 ENOG4108KMM Diguanylate cyclase VEGS12_29900 ENOG4105HZG regulatoR VEGS12_29910 ENOG4105GXM Putative transcription regulator (DUF1323) VEGS12_29930 ENOG4105CN8 Transcriptional regulator VEGS12_29950 ENOG4105EAA nucleoside VEGS12_29960 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) VEGS12_29970 ENOG4108NFH Sugar hydrolase VEGS12_29980 ENOG4108M0I Transcriptional regulator VEGS12_29990 ENOG4105DHU Bile acid VEGS12_30000 ENOG4105VRT cytoplasmic protein VEGS12_30050 ENOG4105C6T cysteine synthase VEGS12_30070 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) VEGS12_30080 ENOG4105C5Y PTS System VEGS12_30100 ENOG4105M0Y VEGS12_30110 ENOG4105C6T cysteine synthase VEGS12_30120 ENOG4108IJ6 ABC transporter VEGS12_30130 ENOG4105ECW sulfate abc transporter VEGS12_30140 ENOG4108I5D sulfate abc transporter VEGS12_30150 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein VEGS12_30160 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr VEGS12_30190 ENOG4105C5Y PTS System VEGS12_30200 ENOG4107S1E Beta-lactamase VEGS12_30210 ENOG4105EZR dyp-type peroxidase family protein VEGS12_30220 ENOG4105E7K (LipO)protein VEGS12_30230 ENOG4105QZU Inner membrane protein YfeZ VEGS12_30250 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase VEGS12_30270 ENOG4108K3Z AraC family transcriptional regulator VEGS12_30280 ENOG4108X49 Ethanolamine utilization protein EutK VEGS12_30290 ENOG4106D67 ethanolamine utilization protein VEGS12_30310 ENOG4105CPD ethanolamine ammonia-lyase VEGS12_30320 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase VEGS12_30330 ENOG4105ENY Ethanolamine utilization protein eutH VEGS12_30340 ENOG4105C0A alcohol dehydrogenase VEGS12_30350 ENOG4107RWI ethanolamine utilization protein eutJ VEGS12_30360 ENOG4108EKI Dehydrogenase VEGS12_30370 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml VEGS12_30380 ENOG4105KNY Microcompartments protein VEGS12_30390 ENOG4107WUY phosphate acetyltransferase VEGS12_30400 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase VEGS12_30410 ENOG4105NDK ethanolamine utilization protein VEGS12_30420 ENOG4106S4J ethanolamine utilization protein EutP VEGS12_30430 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place VEGS12_30440 ENOG4105C6K Malic enzyme VEGS12_30450 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) VEGS12_30460 ENOG4105CV1 Transketolase (EC 2.2.1.1) VEGS12_30470 ENOG4108PVD exported protein VEGS12_30490 ENOG4105BZ8 glutamate synthase VEGS12_30500 ENOG4105BZU Histidine kinase VEGS12_30510 ENOG4105BZS acriflavin resistance protein VEGS12_30520 ENOG4105KUZ arsenate reductase VEGS12_30550 ENOG4106KED esterase YpfH VEGS12_30560 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) VEGS12_30570 ENOG4105CGZ zinc metallopeptidase VEGS12_30580 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A VEGS12_30610 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) VEGS12_30620 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) VEGS12_30630 ENOG4105RH4 Glycine cleavage system transcriptional repressor VEGS12_30640 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen VEGS12_30650 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) VEGS12_30660 ENOG4108JPZ Monovalent cation H antiporter subunit D VEGS12_30670 ENOG4107TDF Formate hydrogenlyase subunit 4 VEGS12_30680 ENOG4105D65 subunit l VEGS12_30690 ENOG4107WQX hydrogenase 4 membrane subunit VEGS12_30700 ENOG4108JPZ Monovalent cation H antiporter subunit D VEGS12_30710 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) VEGS12_30730 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit VEGS12_30740 ENOG4105I6X formate hydrogenlyase maturation VEGS12_30750 ENOG4108JUA Transcriptional regulator VEGS12_30760 ENOG4105TMB Formate nitrite transporter VEGS12_30770 ENOG4105C02 permease VEGS12_30780 ENOG4105ERG peptidase m48, ste24p VEGS12_30790 ENOG4105K89 arsenate reductase VEGS12_30800 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) VEGS12_30810 ENOG4105C2W permease VEGS12_30840 ENOG4108V3E phosphoribosylglycinamide formyltransferase VEGS12_30850 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) VEGS12_30860 ENOG4105C9X ppx gppa phosphatase VEGS12_30870 ENOG4105BZU Histidine kinase VEGS12_30890 ENOG41062G3 Protein of unknown function (DUF2633) VEGS12_30900 ENOG4108ZMA Outer membrane lipoprotein VEGS12_30910 ENOG41066DY Membrane VEGS12_30930 ENOG4105NVB glycoside hydrolase, family 19 VEGS12_31170 ENOG4108TFU terminase (Small subunit) VEGS12_31310 ENOG41076J9 exonuclease VIII VEGS12_31390 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) VEGS12_31410 ENOG4105VPD cellular component movement VEGS12_31440 ENOG4105N21 Membrane VEGS12_31500 ENOG4108JQB penicillin-binding protein 1C VEGS12_31510 ENOG4105DN3 alpha-2-macroglobulin domain protein VEGS12_31520 ENOG4105KHC sulfurtransferase VEGS12_31530 ENOG4105YYA enhanced serine sensitivity protein SseB VEGS12_31550 ENOG4105WVQ Fe-S assembly protein IscX VEGS12_31560 ENOG4108ZIT Ferredoxin, 2FE-2S VEGS12_31600 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins VEGS12_31640 ENOG4105ECY inositol monophosphatase VEGS12_31650 ENOG4107XM9 (LipO)protein VEGS12_31660 ENOG4108MN2 Stationary phase inducible protein CsiE VEGS12_31670 ENOG4105D8G Major Facilitator superfamily VEGS12_31680 ENOG4108W5M transcriptional regulator VEGS12_31690 ENOG4105FUY alpha subunit VEGS12_31740 ENOG4108SB3 DoxX Family VEGS12_31750 ENOG4108ZKT aldose 1-epimerase VEGS12_31760 ENOG4105CPQ Dehydrogenase VEGS12_31770 ENOG4105CNN ABC, transporter VEGS12_31780 ENOG4108F37 ATP-binding component of a transport system VEGS12_31790 ENOG4105FCA ABC transporter periplasmic-binding protein YphF VEGS12_31800 ENOG4107HQ7 repeat protein VEGS12_31810 ENOG4108NZE NAGC-like transcriptional regulator VEGS12_31830 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) VEGS12_31850 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family VEGS12_31860 ENOG4108SKK alpha helix protein VEGS12_31880 ENOG4107WP9 Histidine kinase VEGS12_31890 ENOG4107QIK phosphoribosylformylglycinamidine synthase VEGS12_31910 ENOG4108Z6B deaminase VEGS12_31920 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB VEGS12_31930 ENOG4106G6Q Transcriptional regulator VEGS12_31940 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding VEGS12_31960 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) VEGS12_32000 ENOG4105C3F Signal peptidase i VEGS12_32020 ENOG4105WMJ Positive regulator of sigma E, RseC MucC VEGS12_32030 ENOG4105VQK sigma E regulatory protein, MucB RseB VEGS12_32040 ENOG41069PW sigma-e factor negative regulatory protein VEGS12_32050 ENOG4105EMN RNA polymerase sigma factor VEGS12_32060 ENOG4108IYU L-aspartate oxidase VEGS12_32080 ENOG4105C1J atp-dependent rna helicase VEGS12_32090 ENOG41090KR LysR family transcriptional Regulator VEGS12_32130 ENOG4105EIB trna rrna methyltransferase VEGS12_32140 ENOG4105K63 Thioredoxin VEGS12_32150 ENOG4106IUH DTW domain containing protein VEGS12_32160 ENOG4105CD5 CoA-binding domain protein VEGS12_32170 ENOG4105JIM Phosphatidylserine synthase VEGS12_32180 ENOG4105T42 (LipO)protein VEGS12_32190 ENOG4105CSH Transporter VEGS12_32200 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit VEGS12_32210 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase VEGS12_32220 ENOG4105C34 Pseudouridine synthase VEGS12_32230 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane VEGS12_32240 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA VEGS12_32250 ENOG4105CQC Prephenate dehydratase VEGS12_32260 ENOG4105EHE chorismate mutase- prephenate dehydrogenase VEGS12_32270 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) VEGS12_32280 ENOG4105QP9 Protein of unknown function (DUF2799) VEGS12_32290 ENOG4108WS1 VEGS12_32300 ENOG4108KHX Diguanylate cyclase VEGS12_32310 ENOG41090EK ompa motb domain protein VEGS12_32360 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY VEGS12_32380 ENOG4106KVJ cytochrome C assembly protein VEGS12_32390 ENOG4108JU6 CBS domain protein VEGS12_32420 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) VEGS12_32430 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) VEGS12_32450 ENOG4108Z1B Cyclase dehydrase VEGS12_32480 ENOG4108MGN ATP-binding component of a transport system VEGS12_32480 ENOG4108MGN ATP-binding component of a transport system VEGS12_32530 ENOG4105E54 alpha-amylase VEGS12_32540 ENOG4105E54 alpha-amylase VEGS12_32560 ENOG4105D5U fad dependent oxidoreductase VEGS12_32570 ENOG4105C26 Dehydrogenase VEGS12_32580 ENOG4108JPW Aminotransferase VEGS12_32590 ENOG4105C85 amino acid VEGS12_32600 ENOG4108PVQ transcriptional regulator VEGS12_32610 ENOG4109066 lysm domain bon superfamily protein VEGS12_32620 ENOG4105VPI YqaE family transport protein VEGS12_32630 ENOG41080HT Transcriptional regulator, arsr family VEGS12_32640 ENOG4108V62 Rhodanese domain protein VEGS12_32650 ENOG4108X73 DNA- binding protein VEGS12_32660 ENOG4108RNS Exports L-alanine (By similarity) VEGS12_32670 ENOG4108WMJ Protein of unknown function (DUF2002) VEGS12_32680 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) VEGS12_32690 ENOG4105WAZ (Glutaredoxin-like protein) NrdH VEGS12_32710 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) VEGS12_32720 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) VEGS12_32730 ENOG4108IJ7 Glycine betaine VEGS12_32740 ENOG4108HQS Glycine betaine VEGS12_32750 ENOG4105GIJ Glycine betaine VEGS12_32770 ENOG4108UMN azlc family VEGS12_32780 ENOG4105ZED uncharacterized protein ygaH VEGS12_32790 ENOG4105NTK Transcriptional repressor Mpra VEGS12_32800 ENOG4105CW7 secretion protein, HlyD family VEGS12_32810 ENOG4105C0R drug resistance transporter emrb qaca subfamily VEGS12_32840 ENOG4105W39 Membrane VEGS12_32850 ENOG4107VXZ Hydrolase VEGS12_32860 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) VEGS12_32900 ENOG4107TH8 cina domain protein VEGS12_32910 ENOG4105CVE Lytic murein transglycosylase VEGS12_32920 ENOG410787A Pts system, glucitol sorbitol-specific VEGS12_32930 ENOG4105DZY Pts system, glucitol sorbitol-specific VEGS12_32940 ENOG4105VI0 Pts system, glucitol sorbitol-specific VEGS12_32950 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase VEGS12_32960 ENOG4105J92 DNA-binding transcriptional activator GutM VEGS12_32970 ENOG410804X Transcriptional regulator VEGS12_33020 ENOG4105C8H hydrogenase maturation protein Hypf VEGS12_33030 ENOG4108RC0 Electron transport protein VEGS12_33040 ENOG4105DDV Transcriptional regulator (LacI family VEGS12_33050 ENOG4105C5Y PTS System VEGS12_33060 ENOG4105CS2 ec 3.2.1.21 VEGS12_33070 ENOG4108Z3N Transcriptional regulator VEGS12_33090 ENOG4108MG9 hydrogenase 3 maturation protease VEGS12_33100 ENOG4105I6X formate hydrogenlyase maturation VEGS12_33110 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit VEGS12_33120 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit VEGS12_33130 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) VEGS12_33140 ENOG4107TDF Formate hydrogenlyase subunit 4 VEGS12_33150 ENOG4107R30 NADH dehydrogenase VEGS12_33160 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) VEGS12_33170 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA VEGS12_33180 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) VEGS12_33190 ENOG4107RSS Hydrogenase accessory protein HypB VEGS12_33200 ENOG41083WG hydrogenase assembly chaperone VEGS12_33210 ENOG4105CQS hydrogenase expression formation protein HypD VEGS12_33220 ENOG4105C45 hydrogenase expression formation protein (HypE) VEGS12_33230 ENOG4108JUA Transcriptional regulator VEGS12_33240 ENOG4105VXR cytoplasmic protein VEGS12_33260 ENOG4105MEW serine threonine protein phosphatase VEGS12_33270 ENOG4105MVE transcriptional regulator VEGS12_33280 ENOG4105ZXK Dehydrogenase VEGS12_33290 ENOG4105G63 Type III effector Hrp-dependent VEGS12_33300 ENOG4105FB2 class II Aldolase VEGS12_33310 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) VEGS12_33320 ENOG4105C6Z Gluconate VEGS12_33330 ENOG4105KZM cytoplasmic protein VEGS12_33340 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) VEGS12_33350 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase VEGS12_33370 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) VEGS12_33380 ENOG4108K5P (LipO)protein VEGS12_33460 ENOG4105N0Z inner membrane protein ygbE VEGS12_33490 ENOG4105C11 sulfate adenylyltransferase), subunit 2 VEGS12_33500 ENOG4108MXK alkaline phosphatase isozyme conversion VEGS12_33510 ENOG4105PWE CRISPR-associated protein cas2 VEGS12_33520 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) VEGS12_33540 ENOG4108VWQ crispr-associated protein VEGS12_33550 ENOG41060M0 Crispr-associated protein, cse4 family VEGS12_33570 ENOG4105CYR Crispr-associated protein, cse1 family VEGS12_33590 ENOG4105DTT CRISPR-associated helicase, cas3 VEGS12_33600 ENOG4107635 Hok Gef family protein VEGS12_33640 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase VEGS12_33650 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase VEGS12_33660 ENOG4105WQV ferredoxin-like protein VEGS12_33670 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator VEGS12_33680 ENOG4105YBM electron transfer flavoprotein subunit ygcQ VEGS12_33690 ENOG4106IKH Electron transfer flavoprotein VEGS12_33700 ENOG4105C54 Major Facilitator superfamily VEGS12_33710 ENOG4107R3A FAD linked oxidase domain protein VEGS12_33720 ENOG4105CHR reductase VEGS12_33730 ENOG4108ITV Inner membrane protein yqcE VEGS12_33740 ENOG4108CWB sugar kinase ygcE VEGS12_33750 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) VEGS12_33770 ENOG4105HA9 of methanol dehydrogenase type VEGS12_33810 ENOG4105DXN mazG family VEGS12_33820 ENOG4105MZG transcriptional modulator of maze toxin, mazf VEGS12_33830 ENOG4106A2Z transcriptional regulator antitoxin, MazE VEGS12_33840 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) VEGS12_33860 ENOG4105BZU Histidine kinase VEGS12_33870 ENOG4105EQX glucarate dehydratase VEGS12_33880 ENOG4105EQX glucarate dehydratase VEGS12_33890 ENOG4105DJB Major Facilitator Superfamily VEGS12_33900 ENOG4105QDK Flavodoxin VEGS12_33910 ENOG4105DR9 pseudouridine synthase VEGS12_33920 ENOG4105WP7 tRNA pseudouridine synthase C VEGS12_33950 ENOG4105EWT decarboxylase family VEGS12_33960 ENOG4105C44 Serine transporter VEGS12_33970 ENOG4105EJQ L-serine dehydratase VEGS12_33990 ENOG4105C0A alcohol dehydrogenase VEGS12_34000 ENOG4107W7X Aldolase VEGS12_34010 ENOG4105EDR glucose galactose transporter VEGS12_34030 ENOG4105CMG Carbohydrate kinase VEGS12_34050 ENOG4107EDW L-fucose operon activator VEGS12_34070 ENOG4105M08 Membrane VEGS12_34080 ENOG4105ETT transcriptional Regulator, LysR family VEGS12_34090 ENOG4105M5B (LipO)protein VEGS12_34100 ENOG4105C9B Cysteine desulfurase VEGS12_34110 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) VEGS12_34120 ENOG4105CUZ uba thif-type nad fad binding protein VEGS12_34130 ENOG4105CA3 membrane-bound lytic murein transglycosylase VEGS12_34140 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase VEGS12_34150 ENOG4108EKC n-acetylglutamate synthase VEGS12_34160 ENOG4107QYX exodeoxyribonuclease v alpha VEGS12_34170 ENOG4107QKA exodeoxyribonuclease V beta VEGS12_34180 ENOG4107QXK peptidase VEGS12_34190 ENOG4105DSY exodeoxyribonuclease V, gamma VEGS12_34200 ENOG4105RVB Prepilin peptidase dependent protein c VEGS12_34210 ENOG4105SEN Protein of unknown function (DUF2509) VEGS12_34220 ENOG4105JCS prepilin peptidase dependent protein VEGS12_34230 ENOG4105IPU prepilin peptidase dependent protein A VEGS12_34260 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase VEGS12_34290 ENOG4105EE5 Membrane protein terC VEGS12_34300 ENOG4105SUV lipoprotein YgdR VEGS12_34310 ENOG4105CPC Aldo Keto reductase VEGS12_34320 ENOG4107S74 Lysophospholipid transporter LplT VEGS12_34340 ENOG41060NJ transcriptional regulator VEGS12_34360 ENOG4105RQF LysR family Transcriptional regulator VEGS12_34380 ENOG4107QNK )-transporter VEGS12_34390 ENOG4105CHR reductase VEGS12_34410 ENOG4105CHU acetyl-coa acetyltransferase VEGS12_34420 ENOG4108MHD transport protein VEGS12_34430 ENOG4105ISV protein with bipartite regulator domain VEGS12_34440 ENOG4108TC1 Transcriptional regulator VEGS12_34450 ENOG4105FV3 VEGS12_34490 ENOG4108YAB Invasion protein VEGS12_34560 ENOG4108RBT type iii secretion VEGS12_34590 ENOG4108RC9 Type III secretion system protein VEGS12_34620 ENOG4108M6W surface presentation of antigens protein SpaS VEGS12_34630 ENOG4108M6W surface presentation of antigens protein SpaS VEGS12_34640 ENOG4108TN6 type iii secretion VEGS12_34650 ENOG4105U07 type iii secretion VEGS12_34660 ENOG41075IY surface presentation of antigens protein SpaP VEGS12_34690 ENOG4108T88 VEGS12_34700 ENOG4108K5P (LipO)protein VEGS12_34710 ENOG4105C7W Xanthine dehydrogenase VEGS12_34720 ENOG4108HR6 Dehydrogenase VEGS12_34730 ENOG4108UTP (2Fe-2S)-binding domain protein VEGS12_34740 ENOG4108JUB Transcriptional regulator VEGS12_34750 ENOG4105IW6 Carbamoyltransferase VEGS12_34760 ENOG4107RCH Diaminopropionate ammonia-lyase VEGS12_34770 ENOG4107S4Y M20 DapE family protein YgeY VEGS12_34790 ENOG4105C5B carbamate kinase VEGS12_34800 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family VEGS12_34810 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC VEGS12_34820 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase VEGS12_34830 ENOG4105BZ8 glutamate synthase VEGS12_34840 ENOG4107UUR Chlorohydrolase aminohydrolase VEGS12_34850 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase VEGS12_34860 ENOG4105C7W Xanthine dehydrogenase VEGS12_34870 ENOG4105C2W permease VEGS12_34880 ENOG4107QUY Guanine deaminase VEGS12_34890 ENOG4105C7N Xanthine uracil vitamin C permease VEGS12_34900 ENOG4108R8B oxidoreductase Fe-S subunit VEGS12_34910 ENOG4105BZ8 glutamate synthase VEGS12_34920 ENOG4105C2W permease VEGS12_34960 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) VEGS12_34970 ENOG4105T95 Thiol disulfide interChange protein VEGS12_34980 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) VEGS12_34990 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) VEGS12_35000 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB VEGS12_35010 ENOG4105Y75 tpr repeat protein VEGS12_35040 ENOG4108UT2 hemolysin iii VEGS12_35060 ENOG4105CS2 ec 3.2.1.21 VEGS12_35070 ENOG4105CYX Short-chain dehydrogenase reductase Sdr VEGS12_35110 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family VEGS12_35120 ENOG4105D0A hydroxylase VEGS12_35130 ENOG4107RAQ aminopeptidase VEGS12_35160 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase VEGS12_35170 ENOG4108JQ1 Dehydrogenase VEGS12_35210 ENOG4105D5P Methylmalonyl-coA mutase VEGS12_35220 ENOG4105DJT lAO AO transport system ATPase VEGS12_35230 ENOG4108M7F enoyl-CoA hydratase isomerase VEGS12_35240 ENOG4105CYC Transferase VEGS12_35250 ENOG4105DEQ transcriptional regulator VEGS12_35260 ENOG4105MPN Membrane VEGS12_35270 ENOG4108ZUB Lysine exporter protein (Lyse ygga) VEGS12_35280 ENOG4105D64 Mechanosensitive ion channel VEGS12_35290 ENOG4105D2N Aldolase VEGS12_35350 ENOG4108JJB ABC transporter VEGS12_35360 ENOG4108JJB ABC transporter VEGS12_35370 ENOG4107Z1W Fructose transport system kinase VEGS12_35380 ENOG4108R4K DNA-binding, transcriptional regulator VEGS12_35390 ENOG4108Q8A Fructose-1,6-bisphosphatase VEGS12_35400 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein VEGS12_35410 ENOG4105CTS PTS system mannitol-specific VEGS12_35420 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia VEGS12_35430 ENOG4105CV1 Transketolase (EC 2.2.1.1) VEGS12_35440 ENOG4108K0D peptidase, M48 VEGS12_35500 ENOG4107QNK )-transporter VEGS12_35520 ENOG4105RWS endonuclease I VEGS12_35530 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) VEGS12_35540 ENOG4105D7Z glutathione synthase VEGS12_35570 ENOG4105CZX twitching motility protein VEGS12_35580 ENOG4105DFA alanine racemase domain protein VEGS12_35590 ENOG4108VIA integral membrane protein VEGS12_35610 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) VEGS12_35620 ENOG4105CSA Coproporphyrinogen iii oxidase VEGS12_35630 ENOG4106MH3 alpha helix chain VEGS12_35640 ENOG4105HDK L-asparaginase VEGS12_35650 ENOG4105K33 Periplasmic Protein VEGS12_35660 ENOG41090ED Protein with unknown function (DUF469) VEGS12_35680 ENOG4105CEN a g-specific adenine glycosylase VEGS12_35710 ENOG4105EAA nucleoside VEGS12_35720 ENOG4105CXN decarboxylase VEGS12_35730 ENOG4108UQV Membrane VEGS12_35740 ENOG4105U1E general secretion pathway protein M VEGS12_35780 ENOG4105X5Z General secretion pathway protein I VEGS12_35800 ENOG4108VAU general secretion pathway protein G VEGS12_35810 ENOG4105D7Q type ii secretion system VEGS12_35820 ENOG4107QHF type ii secretion system protein e VEGS12_35850 ENOG410765S (LipO)protein VEGS12_35890 ENOG4105DAA L-lactate VEGS12_35900 ENOG4107QP3 malate synthase g VEGS12_35910 ENOG4108ZJF Glcg protein VEGS12_35920 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) VEGS12_35930 ENOG4105EU8 FAD linked oxidase domain protein VEGS12_35940 ENOG4105CQB FAD linked oxidase domain protein VEGS12_35950 ENOG4108KWP DNA-binding transcriptional regulator GlcC VEGS12_35970 ENOG4107RCI amp-dependent synthetase and ligase VEGS12_35990 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) VEGS12_36000 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) VEGS12_36020 ENOG4108M8S permease YjgP YjgQ family protein VEGS12_36030 ENOG4108UUE Transcriptional regulator VEGS12_36050 ENOG4108S55 polysaccharide biosynthesis protein VEGS12_36060 ENOG4106FPV ATP-binding protein YghR VEGS12_36070 ENOG4108NDC ATP-binding protein yghS VEGS12_36080 ENOG4108GH0 ATP-binding protein yghT VEGS12_36090 ENOG4105CJ3 phosphate transporter VEGS12_36100 ENOG4106032 Glutathionylspermidine synthase VEGS12_36110 ENOG4105CYM Glutathione S-transferase VEGS12_36130 ENOG41082MF Hydrogenase assembly chaperone hypC hupF VEGS12_36140 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) VEGS12_36150 ENOG4108WGS hydrogenase 2-specific chaperone VEGS12_36160 ENOG4108USZ hydrogenase VEGS12_36170 ENOG4105DPX Hydrogenase, large subunit VEGS12_36180 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit VEGS12_36190 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein VEGS12_36200 ENOG4105E3S small subunit VEGS12_36210 ENOG410900S Protein of unknown function (DUF2623) VEGS12_36230 ENOG4105CPC Aldo Keto reductase VEGS12_36250 ENOG4105CYX Short-chain dehydrogenase reductase Sdr VEGS12_36260 ENOG4108ZZF transport protein (ExbD) VEGS12_36270 ENOG4105CWK Biopolymer transport protein, ExbB VEGS12_36280 ENOG4105C28 cystathionine VEGS12_36290 ENOG4108K81 inner membrane protein YghB VEGS12_36300 ENOG4105CF7 AraC family transcriptional regulator VEGS12_36310 ENOG4108I6A alcohol dehydrogenase VEGS12_36320 ENOG4105CV8 reductase VEGS12_36330 ENOG4105ZKC Conserved Protein VEGS12_36350 ENOG4105CCT upf0313 protein VEGS12_36360 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) VEGS12_36370 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase VEGS12_36380 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) VEGS12_36390 ENOG4105F4I Transcriptional regulator VEGS12_36400 ENOG4105H4F exported protein VEGS12_36410 ENOG4105XJC Two component transcriptional regulator (Winged helix family VEGS12_36420 ENOG4105DHQ Histidine kinase VEGS12_36430 ENOG4107DEU Inner membrane protein YgiZ VEGS12_36440 ENOG4105NF4 modulator of drug activity VEGS12_36450 ENOG4105VRH Antibiotic biosynthesis monooxygenase VEGS12_36460 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) VEGS12_36470 ENOG4105IPS esterase VEGS12_36480 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) VEGS12_36490 ENOG4108SX3 cytoplasmic protein VEGS12_36500 ENOG41087AY ADP-Ribose pyrophosphatase VEGS12_36510 ENOG4105DFG type I secretion outer membrane protein VEGS12_36530 ENOG4106032 Glutathionylspermidine synthase VEGS12_36540 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b VEGS12_36580 ENOG4105W0Z cytoplasmic protein VEGS12_36590 ENOG4105H8W Fimbrial protein VEGS12_36610 ENOG4108TTM chaperone VEGS12_36620 ENOG4108MY7 Fimbrial VEGS12_36640 ENOG4105PV3 Inner membrane protein yqiJ VEGS12_36650 ENOG4107S78 Band 7 protein VEGS12_36680 ENOG4105I7R Adenylate cyclase VEGS12_36690 ENOG4106MWK domain protein VEGS12_36720 ENOG4107ZVW dihydroneopterin aldolase VEGS12_36740 ENOG4105EJC lysr family transcriptional regulator VEGS12_36750 ENOG4106DSS Tartrate dehydratase subunit alpha VEGS12_36760 ENOG4107GFK fumarate VEGS12_36770 ENOG4107QPK )-transporter VEGS12_36800 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) VEGS12_36810 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) VEGS12_36830 ENOG4105Q26 Siderophore-interacting protein VEGS12_36840 ENOG4105NTW Transcriptional regulator VEGS12_36850 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor VEGS12_36870 ENOG4108Y51 tRNA-binding protein VEGS12_36880 ENOG4105CQ4 Transcriptional regulator VEGS12_36890 ENOG4105CNT hydrolase family 2 VEGS12_36900 ENOG4105FK9 beta-D-galactosidase beta subunit VEGS12_36910 ENOG4105E5D amino acid VEGS12_36920 ENOG4107W6W Conserved Protein VEGS12_36930 ENOG4107WCA isomerase VEGS12_36940 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase VEGS12_36950 ENOG4108Z3N Transcriptional regulator VEGS12_36970 ENOG4108VKG metal-dependent hydrolase VEGS12_36980 ENOG4108UB4 uncharacterized protein ygjQ VEGS12_36990 ENOG4105EE0 oxidoreductase VEGS12_37000 ENOG4105DU1 integral membrane protein, terc VEGS12_37010 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) VEGS12_37020 ENOG4105P66 Membrane VEGS12_37030 ENOG4105CTX dehydratase VEGS12_37050 ENOG4105DPW Major facilitator superfamily MFS_1 VEGS12_37100 ENOG4107YCY Transcriptional regulator VEGS12_37110 ENOG4106W5V Membrane VEGS12_37120 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) VEGS12_37130 ENOG4105WAY exported protein VEGS12_37140 ENOG4105NE1 Conserved Protein VEGS12_37150 ENOG41090KG Inner membrane protein YqjE VEGS12_37160 ENOG4105YJD VEGS12_37170 ENOG4108VBZ doxx family VEGS12_37180 ENOG4105CHF Glutathione S-transferase VEGS12_37190 ENOG4105KAF membrAne VEGS12_37200 ENOG4105KAF membrAne VEGS12_37210 ENOG4105CWB LysR family transcriptional Regulator VEGS12_37220 ENOG4108CNN domain protein VEGS12_37230 ENOG4106D80 Uncharacterized protein YhaL VEGS12_37250 ENOG4105C44 Serine transporter VEGS12_37260 ENOG4105EJQ L-serine dehydratase VEGS12_37270 ENOG4105KME endoribonuclease L-psp VEGS12_37280 ENOG4105C6N Formate acetyltransferase VEGS12_37290 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) VEGS12_37310 ENOG4105C7B Threonine dehydratase VEGS12_37320 ENOG410811B TRANSCRIPTIONal VEGS12_37350 ENOG4105BZW Glycerate kinase VEGS12_37360 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase VEGS12_37380 ENOG4105DJB Major Facilitator Superfamily VEGS12_37390 ENOG4105CTX dehydratase VEGS12_37400 ENOG4105ZEG Suppressor protein VEGS12_37410 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression VEGS12_37420 ENOG4105E98 transcriptional regulator DeoR family VEGS12_37440 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB VEGS12_37460 ENOG4105F3R pts system mannose fructose sorbose family iid VEGS12_37470 ENOG4108YTN IIa component VEGS12_37480 ENOG4105CE4 GlcNAc 6-P deacetylase VEGS12_37490 ENOG4105E70 isomerase VEGS12_37510 ENOG4108UZY PTS System VEGS12_37520 ENOG4105ETZ PTS System VEGS12_37530 ENOG4105F3R pts system mannose fructose sorbose family iid VEGS12_37540 ENOG4106HBN Galactosamine-6-phosphate isomerase VEGS12_37550 ENOG4105Q10 Fimbrial-like protein VEGS12_37560 ENOG4108VCD Chaperone VEGS12_37570 ENOG4105CW0 outer membrane usher protein VEGS12_37580 ENOG4105I74 Fimbrial protein VEGS12_37590 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) VEGS12_37630 ENOG4105W4M Transport-associated protein VEGS12_37640 ENOG4107S21 permease VEGS12_37650 ENOG4105K4T epimerase VEGS12_37660 ENOG4107R7Y intracellular protease Pfpi family VEGS12_37690 ENOG4108YYD acetyltransferase VEGS12_37730 ENOG4105DEN Luciferase family VEGS12_37740 ENOG4105CIC tryptophan-specific transport protein VEGS12_37750 ENOG4105C1J atp-dependent rna helicase VEGS12_37820 ENOG4105CHV Transcription elongation factor NusA VEGS12_37850 ENOG4105DIJ Phosphoethanolamine transferase VEGS12_37860 ENOG4105NTZ Preprotein translocase subunit SecG VEGS12_37880 ENOG4105EEI dihydropteroate synthase VEGS12_37890 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) VEGS12_37910 ENOG4105HBR Rna-binding protein VEGS12_37920 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) VEGS12_37930 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase VEGS12_37950 ENOG4105QYV Membrane VEGS12_37980 ENOG4105EAH synthase VEGS12_37990 ENOG4105HVQ Regulatory factor of maltose metabolism VEGS12_38010 ENOG4105VFK BolA family VEGS12_38020 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane VEGS12_38030 ENOG4105E3I toluene tolerance VEGS12_38040 ENOG4107PE3 Mammalian cell entry related domain protein VEGS12_38050 ENOG4105CY3 ABC transporter, permease VEGS12_38060 ENOG4105DHJ ABC, transporter VEGS12_38070 ENOG4105FEU K -dependent Na -Ca exchanger VEGS12_38080 ENOG4105C2X Arabinose 5-phosphate isomerase VEGS12_38090 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase VEGS12_38100 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) VEGS12_38110 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA VEGS12_38120 ENOG4108IUZ ABC transporter VEGS12_38130 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) VEGS12_38140 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA VEGS12_38150 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN VEGS12_38170 ENOG41080Z8 PHOSPHOCARRIER protein VEGS12_38180 ENOG4108NIH transferase activity, transferring phosphorus-containing groups VEGS12_38200 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain VEGS12_38210 ENOG4105BZU Histidine kinase VEGS12_38220 ENOG4105N5T Radical SAM Protein VEGS12_38230 ENOG4105CBC glutamate synthase VEGS12_38240 ENOG4105BZ8 glutamate synthase VEGS12_38250 ENOG4105DFS Conserved Protein VEGS12_38260 ENOG4108R66 Conserved Protein VEGS12_38290 ENOG4105JHE Major Facilitator Superfamily VEGS12_38310 ENOG4108QBF Transcriptional regulator VEGS12_38320 ENOG4105CEE C4-dicarboxylate transporter VEGS12_38330 ENOG4105KB2 stringent starvation protein b VEGS12_38340 ENOG4107MKT Stringent starvation protein a VEGS12_38370 ENOG4105D6Z AFG1 family ATPase VEGS12_38380 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III VEGS12_38390 ENOG4105C0H protease VEGS12_38400 ENOG4105C0H protease VEGS12_38430 ENOG4105RID UPF0379 protein yhcN VEGS12_38440 ENOG4105UNR (Barnase) inhibitor VEGS12_38470 ENOG4105ZQC membrane protein AaeX VEGS12_38480 ENOG4105CR8 Transcriptional regulator VEGS12_38490 ENOG4105D1U peptidase U62 modulator of DNA gyrase VEGS12_38500 ENOG4105QD6 exported protein VEGS12_38510 ENOG4105C03 ribonuclease VEGS12_38530 ENOG4105VQ7 Rod shape-determining protein MreD VEGS12_38540 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) VEGS12_38560 ENOG41062P1 Diguanylate cyclase phosphodiesterase VEGS12_38570 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family VEGS12_38590 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein VEGS12_38600 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase VEGS12_38610 ENOG4105RG0 Membrane VEGS12_38620 ENOG4108IA2 Sodium pantothenate symporter VEGS12_38640 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) VEGS12_38660 ENOG4105CEC DNA methylase N-4 N-6 VEGS12_38670 ENOG4108XG4 DNA-binding transcriptional regulator VEGS12_38680 ENOG4105C1P efflux transporter, rnd family, mfp subunit VEGS12_38690 ENOG4105BZS acriflavin resistance protein VEGS12_38700 ENOG4105XCM membrane LIPOPROTEIN VEGS12_38720 ENOG4105EZ7 amino acid ABC transporter VEGS12_38730 ENOG4105DRP amino acid AbC transporter VEGS12_38740 ENOG4105CDA abc transporter atp-binding protein VEGS12_38750 ENOG4108Z0R Transferase VEGS12_38760 ENOG4105SG3 Protein of unknown function (DUF1488) VEGS12_38810 ENOG4105C79 DNA protecting protein DprA VEGS12_38850 ENOG4105C1A potassium transporter peripheral membrane VEGS12_38870 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system VEGS12_38880 ENOG4105W1Y Transcriptional regulator VEGS12_38890 ENOG4105VTS DnaJ-like, subfamily C VEGS12_38950 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) VEGS12_39040 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) VEGS12_39130 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) VEGS12_39180 ENOG4108UQY Iron-storage protein VEGS12_39190 ENOG4105W53 bacterioferritin-associated ferredoxin VEGS12_39270 ENOG4105WWK YheO domain protein VEGS12_39280 ENOG4108V1T peptidylprolyl cis-trans isomerase VEGS12_39300 ENOG4108YZY peptidylprolyl cis-trans isomerase VEGS12_39310 ENOG4105VKU nucleicacid-binding protein VEGS12_39340 ENOG4105C5H ABC transporter VEGS12_39350 ENOG4105DNZ Alpha Beta Hydrolase VEGS12_39370 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) VEGS12_39380 ENOG4108UKZ OsmC family VEGS12_39400 ENOG410613R integral membrane protein, YccS YhfK family VEGS12_39410 ENOG4105C8Y Acetylornithine aminotransferase VEGS12_39420 ENOG4105DDQ anthranilate synthase VEGS12_39430 ENOG4105MZU cell filamentation protein VEGS12_39450 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) VEGS12_39470 ENOG4107QZF nitrite reductase NADPH large subunit VEGS12_39480 ENOG4105WZK nitrite reductase NADPH small subunit VEGS12_39490 ENOG4107V9H nitrite transporter VEGS12_39510 ENOG4105VYH VEGS12_39520 ENOG4107QHQ amino acid VEGS12_39530 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine VEGS12_39540 ENOG4107Y0V Not clear, may be involved in an isomerization step VEGS12_39550 ENOG4108KPW sugar kinase VEGS12_39560 ENOG4105FDP GntR family transcriptional regulator VEGS12_39570 ENOG4106PKC pyridoxal phosphate binding VEGS12_39580 ENOG4106M0N transport system permease protein VEGS12_39590 ENOG4105MUZ Protein of unknown function DUF2620 VEGS12_39600 ENOG41080QX K07048 phosphotriesterase-related protein VEGS12_39610 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) VEGS12_39620 ENOG4108626 Racemase VEGS12_39630 ENOG4105RMW regulation of transcription, DNA-dependent VEGS12_39640 ENOG4108M21 VEGS12_39650 ENOG4105C31 Tryptophanyl-tRNA synthetase VEGS12_39660 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) VEGS12_39670 ENOG4105DJV ribulose-phosphate 3-epimerase VEGS12_39680 ENOG4105DFE Dna adenine methylase VEGS12_39690 ENOG4105EGB membrane protein DamX VEGS12_39720 ENOG4105E4G Type IV pilus VEGS12_39730 ENOG4105ITY Required for the use of extracellular DNA as a nutrient VEGS12_39740 ENOG4105XPX DNA utilization protein HofO VEGS12_39750 ENOG41065NF Fimbrial assembly family protein VEGS12_39760 ENOG4108U1Q Pilus assembly protein VEGS12_39770 ENOG4108JQC penicillin-binding protein 1A VEGS12_39780 ENOG4107RK2 ADP-ribose diphosphatase NudE VEGS12_39790 ENOG4105DQY intracellular growth attenuator VEGS12_39800 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 VEGS12_39810 ENOG4105VEJ Heat shock protein VEGS12_39830 ENOG4108MAJ Membrane VEGS12_39870 ENOG4105E0F Histidine kinase VEGS12_39890 ENOG4108RRZ Transcription elongation factor GreB VEGS12_39900 ENOG4105BZM domain protein VEGS12_39910 ENOG4105XFK Ferrous iron transport protein A VEGS12_39920 ENOG4105CE1 Ferrous iron transport protein b VEGS12_39940 ENOG4105DNE Transposase VEGS12_39970 ENOG4105C6Z Gluconate VEGS12_39980 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) VEGS12_39990 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) VEGS12_40020 ENOG4105E0Y RtcB Protein VEGS12_40030 ENOG4105CYB regulatoR VEGS12_40040 ENOG4105E98 transcriptional regulator DeoR family VEGS12_40070 ENOG4105C6V Glycerol-3-phosphate dehydrogenase VEGS12_40110 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) VEGS12_40160 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) VEGS12_40170 ENOG41076UM multiple antibiotic resistance (MarC)-related protein VEGS12_40180 ENOG4105C6Z Gluconate VEGS12_40190 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family VEGS12_40200 ENOG4105DIQ Transcriptional regulator VEGS12_40210 ENOG4105C2I pirin domain protein VEGS12_40220 ENOG4105D9R oxidoreductase VEGS12_40240 ENOG4105WCN acetyltransferase VEGS12_40250 ENOG4105GMB type VI secretion system effector, hcp1 family VEGS12_40280 ENOG4105GMB type VI secretion system effector, hcp1 family VEGS12_40310 ENOG4106FA4 VEGS12_40320 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) VEGS12_40330 ENOG4105WC8 Conserved Protein VEGS12_40340 ENOG4107T6V glycerophosphoryl diester phosphodiesterase VEGS12_40360 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component VEGS12_40370 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component VEGS12_40380 ENOG4105BZ7 extracellular solute-binding protein family 1 VEGS12_40390 ENOG4108IV0 ABC, transporter VEGS12_40400 ENOG4105C0Z ABC transporter VEGS12_40410 ENOG4105CF8 branched-chain amino acid ABC transporter, permease VEGS12_40420 ENOG4105C32 Amino acid ABC transporter (Permease) VEGS12_40430 ENOG4105CP9 extracellular ligand-binding receptor VEGS12_40440 ENOG4105U59 -acetyltransferase VEGS12_40470 ENOG4105CP9 extracellular ligand-binding receptor VEGS12_40480 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) VEGS12_40490 ENOG4105CRP Part of the ABC transporter FtsEX involved in VEGS12_40500 ENOG4105CAK Cell division ATP-binding protein ftsE VEGS12_40510 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) VEGS12_40520 ENOG4106H78 methyltransferase VEGS12_40530 ENOG4105MG3 Membrane VEGS12_40550 ENOG4107FS9 Membrane VEGS12_40580 ENOG4105EX9 Membrane VEGS12_40590 ENOG4108W1V Lipoprotein VEGS12_40600 ENOG4105F9N Major Facilitator Superfamily VEGS12_40610 ENOG4105F9N Major Facilitator Superfamily VEGS12_40620 ENOG4105DSF transport protein VEGS12_40630 ENOG4107YAK holo-(acyl carrier protein) synthase 2 VEGS12_40640 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein VEGS12_40650 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component VEGS12_40660 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component VEGS12_40670 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) VEGS12_40710 ENOG4105CMI transporter VEGS12_40720 ENOG4105CJ1 ABC, transporter VEGS12_40730 ENOG4105D0S secretion protein (HlyD VEGS12_40760 ENOG4107UNS conserved inner membrane protein VEGS12_40770 ENOG4105CBX hi0933 family VEGS12_40780 ENOG4105CJ3 phosphate transporter VEGS12_40820 ENOG4105DUX Transporter VEGS12_40840 ENOG4105DGW oligopeptidase A VEGS12_40850 ENOG4105D6S protein involved in catabolism of external DNA VEGS12_40860 ENOG4105DC8 reductase VEGS12_40890 ENOG4105KBH arsR family transcriptional regulator VEGS12_40900 ENOG4107R5R arsenical pump membrane protein VEGS12_40910 ENOG4105K89 arsenate reductase VEGS12_40950 ENOG4105Y4Z Outer Membrane Lipoprotein VEGS12_40980 ENOG4105KT7 mgtC SapB transporter VEGS12_40990 ENOG4105XXV Acid-resistance protein VEGS12_41000 ENOG41060V2 Acid-resistance protein VEGS12_41010 ENOG4108YK4 Acid-resistance membrane protein VEGS12_41020 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci VEGS12_41030 ENOG4105C1P efflux transporter, rnd family, mfp subunit VEGS12_41040 ENOG4105BZS acriflavin resistance protein VEGS12_41070 ENOG4105CVK Glutamate decarboxylase VEGS12_41080 ENOG4105CA0 peroxidase VEGS12_41100 ENOG4106S2D Transcriptional regulator VEGS12_41110 ENOG4105CBN LysR family transcriptional regulator VEGS12_41120 ENOG4107H3J ribonuclease VEGS12_41130 ENOG4105CSH Transporter VEGS12_41140 ENOG41066T0 asmA family VEGS12_41150 ENOG4105CMB EAL domain-containing protein VEGS12_41170 ENOG4105CS0 peptidase VEGS12_41190 ENOG4105BZU Histidine kinase VEGS12_41200 ENOG4105EJG cellulose synthase VEGS12_41210 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) VEGS12_41220 ENOG4107EEX Cellulose synthase regulator protein VEGS12_41230 ENOG4107QZ7 Cellulose synthase catalytic subunit VEGS12_41250 ENOG410661M cytoplasmic protein VEGS12_41260 ENOG4105U74 cellulose biosynthesis protein BcsE VEGS12_41270 ENOG4105WQA Cellulose biosynthesis protein BcsF VEGS12_41280 ENOG4105D1V cellulose synthase operon protein YhjU VEGS12_41300 ENOG4105C44 Serine transporter VEGS12_41310 ENOG4108JQ7 (ABC) transporter VEGS12_41320 ENOG4105C3U ABC transporter VEGS12_41330 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component VEGS12_41340 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component VEGS12_41350 ENOG4105DEF Extracellular solute-binding protein, family 5 VEGS12_41360 ENOG4105DIJ Phosphoethanolamine transferase VEGS12_41370 ENOG4106UCC Fimbrial protein VEGS12_41380 ENOG4105MHR Fimbrial protein VEGS12_41390 ENOG4105CW0 outer membrane usher protein VEGS12_41400 ENOG4108VCD Chaperone VEGS12_41410 ENOG4106EAR Fimbrial protein VEGS12_41420 ENOG4105FCD Major Facilitator VEGS12_41430 ENOG4105EAX Putative lipase VEGS12_41440 ENOG4108R3E Dna-3-methyladenine glycosylase i VEGS12_41450 ENOG4105HNP -acetyltransferase VEGS12_41460 ENOG4107QY8 reductase VEGS12_41470 ENOG4108ZG0 Ompa motb domain protein VEGS12_41490 ENOG4106JH6 (LipO)protein VEGS12_41500 ENOG4105MVF Transcriptional regulator VEGS12_41550 ENOG4105MEV Acyl-transferase VEGS12_41560 ENOG4108Z12 YiaAB two helix domain-containing protein VEGS12_41570 ENOG410688U Inner membrane protein yiaB VEGS12_41580 ENOG4105CMG Carbohydrate kinase VEGS12_41600 ENOG4105DFW ABC transporter VEGS12_41610 ENOG4105C2J ABC transporter VEGS12_41620 ENOG4108HWW ABC transporter VEGS12_41630 ENOG4105T16 Transcriptional regulator (AraC family) VEGS12_41640 ENOG4108UR8 BAX protein VEGS12_41650 ENOG4107T9C Alpha amylase catalytic region VEGS12_41660 ENOG4105JKW Valine--pyruvate aminotransferase VEGS12_41670 ENOG4108XIB electron transport protein ysaA VEGS12_41680 ENOG4105J4Q Transcriptional regulator VEGS12_41700 ENOG4108R66 Conserved Protein VEGS12_41710 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter VEGS12_41720 ENOG4105CG6 trap dicarboxylate transporter dctm subunit VEGS12_41730 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit VEGS12_41740 ENOG4105CMG Carbohydrate kinase VEGS12_41750 ENOG4105H6Q decarboxylase VEGS12_41760 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase VEGS12_41770 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase VEGS12_41780 ENOG4105GNX MltA-interacting MipA family protein VEGS12_41790 ENOG4108Q2M Transcriptional regulator VEGS12_41800 ENOG4105EFX secretion protein, HlyD family VEGS12_41810 ENOG4105KK7 inner membrane protein YiaW VEGS12_41830 ENOG4105C26 Dehydrogenase VEGS12_41840 ENOG4105C0A alcohol dehydrogenase VEGS12_41850 ENOG4105EM7 Selenocysteine-specific translation elongation factor VEGS12_41870 ENOG4108U78 Glutathione S-transferase VEGS12_41900 ENOG4105CNA YD repeat protein VEGS12_41920 ENOG4105NUP lyase containing HEAT-repeat VEGS12_41960 ENOG4105EFX secretion protein, HlyD family VEGS12_41970 ENOG4105FP6 Protein of unknown function (DUF3302) VEGS12_41980 ENOG4105CTS PTS system mannitol-specific VEGS12_42000 ENOG4105E61 Mannitol repressor protein VEGS12_42020 ENOG4108YYI Protein of unknown function (DUF2810) VEGS12_42030 ENOG4108WY4 inner membrane lipoprotein VEGS12_42040 ENOG4105EUR Domain-Containing protein VEGS12_42050 ENOG4105DAA L-lactate VEGS12_42060 ENOG41073TP transcriptional regulator VEGS12_42080 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) VEGS12_42090 ENOG4105D7W serine acetyltransferase VEGS12_42120 ENOG4105VW4 glutaredoxin 3 VEGS12_42130 ENOG4107YZP Rhodanese domain protein VEGS12_42150 ENOG41063SB peptidase VEGS12_42160 ENOG4105PXI polysaccharide deacetylase VEGS12_42170 ENOG4105K64 Glycosyl transferase, family 2 VEGS12_42190 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) VEGS12_42210 ENOG4105XA0 heptosyltransferase ii VEGS12_42220 ENOG4105D16 lipopolysaccharide heptosyltransferase i VEGS12_42230 ENOG41068PG O-Antigen polymerase VEGS12_42240 ENOG4105K64 Glycosyl transferase, family 2 VEGS12_42250 ENOG4105X1N Glycosyl transferase family 8 VEGS12_42270 ENOG4105X1N Glycosyl transferase family 8 VEGS12_42280 ENOG4106AH0 Glycosyl Transferase VEGS12_42290 ENOG4107543 (lipo)polysaccharide VEGS12_42300 ENOG4107RJ7 Glycosyl transferase (Group 1 VEGS12_42310 ENOG4105DKP glycosyl transferase, family 9 VEGS12_42320 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase VEGS12_42360 ENOG4105KDC 50s ribosomal protein l28 VEGS12_42380 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase VEGS12_42390 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) VEGS12_42430 ENOG4105DSJ YicC domain protein VEGS12_42440 ENOG4105F5P DNA-damage-inducible protein d VEGS12_42450 ENOG4105EN6 Membrane VEGS12_42480 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) VEGS12_42500 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) VEGS12_42510 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase VEGS12_42520 ENOG4105CB5 ATP-dependent DNA helicase recG VEGS12_42540 ENOG4105D6U Sodium Glutamate Symporter VEGS12_42550 ENOG4105C2W permease VEGS12_42560 ENOG4105JV1 AsmA family VEGS12_42570 ENOG4105CJQ hydrolase, family 31 VEGS12_42580 ENOG4105CT4 transporter VEGS12_42600 ENOG4105S8Q sugar efflux transporter VEGS12_42610 ENOG4108UZ3 Transporter VEGS12_42620 ENOG4105D01 (LipO)protein VEGS12_42630 ENOG4105T8A Uncharacterized protein YicS VEGS12_42650 ENOG4108SAJ Protein of unknown function (DUF1198) VEGS12_42660 ENOG4105C7N Xanthine uracil vitamin C permease VEGS12_42670 ENOG4105CPN adenine deaminase VEGS12_42680 ENOG4105CXY transporter VEGS12_42690 ENOG4105CXY transporter VEGS12_42700 ENOG4105BZU Histidine kinase VEGS12_42710 ENOG4108KX4 response regulator VEGS12_42720 ENOG4105M71 acetolactate synthase 1 regulatory subunit VEGS12_42730 ENOG4105C7K acetolactate synthase VEGS12_42750 ENOG4105E5M Multidrug resistance protein D VEGS12_42760 ENOG4105J13 transcriptional regulator VEGS12_42770 ENOG4105JP4 Inner membrane protein yidG VEGS12_42780 ENOG4105VG5 Membrane VEGS12_42790 ENOG4106DRA Inner membrane protein YidI VEGS12_42800 ENOG4105CBG Sulfatase VEGS12_42810 ENOG4107RUZ Sss sodium solute transporter superfamily VEGS12_42820 ENOG4108AHD Transcriptional regulator VEGS12_42830 ENOG4105F8D glycoside hydrolase family 4 VEGS12_42850 ENOG4105CI1 PTS System VEGS12_42860 ENOG4105FDP GntR family transcriptional regulator VEGS12_42900 ENOG4105R2A (LipO)protein VEGS12_42910 ENOG4105D99 atp gtp-binding protein VEGS12_42930 ENOG4105DJB Major Facilitator Superfamily VEGS12_42950 ENOG4108RTU Aldolase VEGS12_42960 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 VEGS12_42970 ENOG4105EMF GntR family transcriptional regulator VEGS12_42980 ENOG410657R replicase EC 2.7 VEGS12_42990 ENOG410667J hydrolase VEGS12_43000 ENOG4105VP5 Bacterial protein of unknown function (DUF937) VEGS12_43010 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) VEGS12_43030 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) VEGS12_43050 ENOG4105VG0 50S ribosomal protein l34 VEGS12_43080 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) VEGS12_43100 ENOG4108P6C Tryptophan transporter of low affinity VEGS12_43130 ENOG4105E8Q phosphopantetheinyl transferase VEGS12_43140 ENOG4108YYH Nadph-dependent fmn reductase VEGS12_43150 ENOG4105C7N Xanthine uracil vitamin C permease VEGS12_43160 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 VEGS12_43180 ENOG4106611 bacteriocin immunity VEGS12_43190 ENOG4107VKM 6-phosphogluconolactonase VEGS12_43200 ENOG4105DYC esterase VEGS12_43220 ENOG4105CS2 ec 3.2.1.21 VEGS12_43230 ENOG4105C5Y PTS System VEGS12_43240 ENOG4105CID antiterminator VEGS12_43250 ENOG4108UTW Plays a role in the regulation of phosphate uptake VEGS12_43260 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) VEGS12_43270 ENOG4105E2Z phosphate ABC transporter (Permease VEGS12_43280 ENOG4105C8U phosphate abc transporter VEGS12_43290 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) VEGS12_43310 ENOG4105CW0 outer membrane usher protein VEGS12_43330 ENOG4108RQP Major type 1 subunit fimbrin VEGS12_43340 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) VEGS12_43440 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation VEGS12_43470 ENOG4105QTB Flavodoxin VEGS12_43480 ENOG4108VVK transcriptional Regulator, AsnC VEGS12_43500 ENOG4105EV2 VWA domain protein interacting with AAA ATPase VEGS12_43540 ENOG4105C2J ABC transporter VEGS12_43550 ENOG4105CNN ABC, transporter VEGS12_43560 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator VEGS12_43570 ENOG4108RVA ribokinase VEGS12_43580 ENOG4105ETE Transcriptional regulator (LacI family VEGS12_43590 ENOG4105C0R drug resistance transporter emrb qaca subfamily VEGS12_43600 ENOG4107EJG GntR family transcriptional regulator VEGS12_43620 ENOG4108WFC UPF0438 protein yifE VEGS12_43630 ENOG4105C0P Mg chelatase subunit ChlI VEGS12_43650 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit VEGS12_43660 ENOG4105CM2 brancheD-chain amino acid aminotransferase VEGS12_43680 ENOG4105C7B Threonine dehydratase VEGS12_43690 ENOG4105EMY transcriptional regulator VEGS12_43710 ENOG4105KQ5 peptidylprolyl cis-trans isomerase VEGS12_43730 ENOG4105C4R Atp-dependent dna helicase VEGS12_43770 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) VEGS12_43790 ENOG4105ESV Glycosyl transferase, family 4 VEGS12_43800 ENOG4105SFE lipopolysaccharide biosynthesis protein VEGS12_43810 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase VEGS12_43820 ENOG4107QQG Dehydrogenase VEGS12_43830 ENOG4105C1B dTDP-glucose 4-6-dehydratase VEGS12_43840 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) VEGS12_43850 ENOG4108WJ1 acetyltransferase VEGS12_43860 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase VEGS12_43870 ENOG4105EGZ biosynthesis protein VEGS12_43910 ENOG4105C85 amino acid VEGS12_43920 ENOG4105C4X radical SAM domain protein VEGS12_43930 ENOG410601J HemY protein VEGS12_43940 ENOG4105ECF c-methyltransferase VEGS12_43950 ENOG41076E6 Uroporphyrinogen-III Synthase VEGS12_43970 ENOG4107T0K Adenylate cyclase VEGS12_43990 ENOG4105S7Z (LipO)protein VEGS12_44010 ENOG4105CT0 Protein of unknown function, DUF484 VEGS12_44030 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant VEGS12_44040 ENOG4105C4R Atp-dependent dna helicase VEGS12_44050 ENOG4108T58 Mg2 transport protein CorA VEGS12_44060 ENOG4107QUT magnesium and cobalt transport protein CorA VEGS12_44090 ENOG4107QUT magnesium and cobalt transport protein CorA VEGS12_44120 ENOG4105FR1 rard protein VEGS12_44130 ENOG4108VUY thioesterase Superfamily protein VEGS12_44140 ENOG4105HDD phospholipase VEGS12_44150 ENOG4105C9U ATP-dependent DNA helicase RecQ VEGS12_44160 ENOG4105CCF Lysine exporter protein (Lyse ygga) VEGS12_44170 ENOG410829K Lysine exporter protein (Lyse ygga) VEGS12_44180 ENOG4108EUD Lysophospholipase VEGS12_44190 ENOG4105DQF Hydrolase VEGS12_44200 ENOG4105EMK carboxylate amino acid amine transporter VEGS12_44210 ENOG4105DZ2 Transcriptional regulator VEGS12_44230 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) VEGS12_44240 ENOG4108I5U Uridine phosphorylase VEGS12_44250 ENOG4105CGY Dna recombination protein VEGS12_44270 ENOG4105JC1 sterol-binding domain protein VEGS12_44290 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) VEGS12_44300 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) VEGS12_44310 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) VEGS12_44320 ENOG4105F8V Hydrolase, tatD family VEGS12_44330 ENOG4105MDZ Transcriptional activator rfaH VEGS12_44340 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) VEGS12_44350 ENOG4108EX3 reductase VEGS12_44370 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase VEGS12_44390 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein VEGS12_44400 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) VEGS12_44410 ENOG4108RR8 protoporphyrinogen oxidase VEGS12_44420 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b VEGS12_44430 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) VEGS12_44440 ENOG4105PC1 Conserved Protein VEGS12_44450 ENOG4105E27 serine threonine protein kinase VEGS12_44460 ENOG4108Z33 Thiol disulfide Interchange Protein VEGS12_44480 ENOG4106HNH Acyl-transferase VEGS12_44510 ENOG4105C2M dna polymerase I VEGS12_44540 ENOG4105D4P Coproporphyrinogen iii oxidase VEGS12_44550 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family VEGS12_44560 ENOG4105CUX Signal transduction histidine kinase VEGS12_44570 ENOG4105C5F glutamine synthetase VEGS12_44580 ENOG4105CI3 gtp-binding protein typa VEGS12_44590 ENOG4108K85 Transcriptional regulator VEGS12_44600 ENOG4108KHF Resistance protein VEGS12_44610 ENOG4105R9B Major Facilitator VEGS12_44620 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is VEGS12_44630 ENOG4105CT4 transporter VEGS12_44640 ENOG4105CT4 transporter VEGS12_44650 ENOG4105CJQ hydrolase, family 31 VEGS12_44660 ENOG4107WI4 Aldose-1-epimerase VEGS12_44670 ENOG4107QKS N-acylglucosamine 2-epimerase VEGS12_44680 ENOG4105D2M Aldolase VEGS12_44690 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase VEGS12_44700 ENOG4108MGF sugar kinase VEGS12_44710 ENOG4105E98 transcriptional regulator DeoR family VEGS12_44720 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 VEGS12_44750 ENOG4105SUU thioesterase domain VEGS12_44770 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system VEGS12_44800 ENOG41068KX affects formate dehydrogenase-N VEGS12_44820 ENOG4108MG3 formate dehydrogenase VEGS12_44830 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein VEGS12_44850 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) VEGS12_44860 ENOG4108V87 frv operon regulatory protein VEGS12_44870 ENOG4106C3V frv operon regulatory protein VEGS12_44880 ENOG4105CN9 Peptidase m42 family protein VEGS12_44890 ENOG4105DM4 PTS System VEGS12_44900 ENOG41064BA PTS system, fructose-specific, IIA component VEGS12_44980 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) VEGS12_45000 ENOG4108RPX mosc domain containing protein VEGS12_45010 ENOG4105E0F Histidine kinase VEGS12_45020 ENOG4105E3W Two component transcriptional regulator (Winged helix family VEGS12_45030 ENOG4105FMW periplasmic VEGS12_45040 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)