locus-tag	class	description
AM338_00020	COG2207	Transcriptional regulator
AM338_00035	COG4783	chaperone-mediated protein folding
AM338_00040	COG1215	transferase activity, transferring glycosyl groups
AM338_00045	COG5002	protein histidine kinase activity
AM338_00050	COG0745	RESPONSE REGULATOR receiver
AM338_00060	COG1538	Outer membrane efflux protein
AM338_00065	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_00070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_00075	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM338_00080	COG1113	amino acid transport
AM338_00085	COG0668	transmembrane transport
AM338_00090	COG0778	Nitroreductase
AM338_00100	COG3316	Transposase and inactivated derivatives
AM338_00120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM338_00145	COG0438	transferase activity, transferring glycosyl groups
AM338_00150	COG0438	transferase activity, transferring glycosyl groups
AM338_00190	COG3423	Transcriptional regulator
AM338_00210	COG3316	Transposase and inactivated derivatives
AM338_00235	COG3385	transposase activity
AM338_00240	COG2977	Belongs to the P-Pant transferase superfamily
AM338_00245	COG4771	TonB-dependent receptor
AM338_00250	COG2382	esterase
AM338_00255	COG3251	PFAM MbtH domain protein
AM338_00260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM338_00260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM338_00265	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM338_00270	COG1120	ATPase activity
AM338_00275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM338_00280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM338_00290	COG4592	Periplasmic binding protein
AM338_00300	COG1169	isochorismate synthase
AM338_00305	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM338_00310	COG3433	isochorismatase activity
AM338_00310	COG1535	isochorismatase
AM338_00315	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_00320	COG2050	protein possibly involved in aromatic compounds catabolism
AM338_00325	COG1966	Carbon starvation protein
AM338_00330	COG2879	small protein
AM338_00335	COG0371	Dehydrogenase
AM338_00340	COG0436	Aminotransferase
AM338_00345	COG1475	DNA binding
AM338_00350	COG3969	phosphoadenosine phosphosulfate
AM338_00355	COG0583	DNA-binding transcription factor activity
AM338_00365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM338_00370	COG0450	alkyl hydroperoxide reductase
AM338_00375	COG3634	alkyl hydroperoxide reductase activity
AM338_00380	COG0589	response to stress
AM338_00400	COG1063	alcohol dehydrogenase
AM338_00410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM338_00420	COG3719	Belongs to the RNase T2 family
AM338_00425	COG0471	metal ion transport
AM338_00440	COG3051	citrate lyase alpha subunit
AM338_00445	COG2301	Belongs to the HpcH HpaI aldolase family
AM338_00455	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM338_00460	COG3290	protein histidine kinase activity
AM338_00465	COG4565	transcriptional regulatory protein
AM338_00470	COG3069	C4-dicarboxylate transmembrane transporter activity
AM338_00485	COG1278	Cold shock
AM338_00500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM338_00515	COG0583	DNA-binding transcription factor activity
AM338_00535	COG1686	Belongs to the peptidase S11 family
AM338_00540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM338_00545	COG0772	Belongs to the SEDS family
AM338_00550	COG0768	penicillin binding
AM338_00560	COG0799	negative regulation of ribosome biogenesis
AM338_00565	COG0406	alpha-ribazole phosphatase activity
AM338_00575	COG1466	dna polymerase III delta subunit
AM338_00590	COG2888	peptidyl-tyrosine sulfation
AM338_00595	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM338_00605	COG2214	Heat shock protein DnaJ domain protein
AM338_00610	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM338_00620	COG2214	Heat shock protein DnaJ domain protein
AM338_00625	COG0443	Heat shock 70 kDa protein
AM338_00635	COG1126	abc transporter atp-binding protein
AM338_00640	COG0765	amino acid transport
AM338_00645	COG0765	amino acid transport
AM338_00650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_00655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM338_00660	COG4535	Mg2 and Co2 transporter CorC
AM338_00670	COG1702	phosphate starvation-inducible protein PhoH
AM338_00680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM338_00725	COG0367	asparagine synthase
AM338_00735	COG0647	UMP catabolic process
AM338_00740	COG1846	Transcriptional regulator
AM338_00740	COG1940	carbohydrate kinase activity
AM338_00745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM338_00755	COG1263	PTS System
AM338_00755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_00755	COG2190	(PTS) system
AM338_00775	COG0735	belongs to the Fur family
AM338_00785	COG0716	FMN binding
AM338_00795	COG0596	Alpha beta hydrolase
AM338_00800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM338_00805	COG0033	Phosphoglucomutase
AM338_00825	COG0531	amino acid
AM338_00840	COG0745	RESPONSE REGULATOR receiver
AM338_00845	COG2205	protein histidine kinase activity
AM338_00875	COG3209	COG3209 Rhs family protein
AM338_00910	COG3272	Protein of unknown function (DUF1722)
AM338_00915	COG0415	Belongs to the DNA photolyase family
AM338_00920	COG3104	oligopeptide transport
AM338_00925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM338_00930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM338_00935	COG1984	allophanate hydrolase subunit 2
AM338_00950	COG3180	Ammonia monooxygenase
AM338_00955	COG3539	Fimbrial protein
AM338_00960	COG3121	Chaperone
AM338_00965	COG3188	usher protein
AM338_00970	COG3539	Fimbrial protein
AM338_00975	COG0372	Belongs to the citrate synthase family
AM338_00990	COG2009	succinate dehydrogenase
AM338_00995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM338_01000	COG1053	succinate dehydrogenase
AM338_01005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM338_01010	COG0567	Dehydrogenase, E1 component
AM338_01015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM338_01025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM338_01035	COG2188	Transcriptional regulator
AM338_01040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_01040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_01045	COG0383	alpha-mannosidase activity
AM338_01055	COG1271	oxidase subunit
AM338_01060	COG1294	oxidase, subunit
AM338_01065	COG4890	Cyd operon protein YbgT
AM338_01070	COG3790	cyd operon protein YbgE
AM338_01075	COG0824	Thioesterase
AM338_01080	COG0811	peptide transport
AM338_01085	COG0848	biopolymer transport protein
AM338_01090	COG3064	Membrane
AM338_01100	COG2885	chlorophyll binding
AM338_01105	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM338_01155	COG3201	nicotinamide mononucleotide transporter
AM338_01160	COG1230	cation diffusion facilitator family transporter
AM338_01175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM338_01185	COG2017	converts alpha-aldose to the beta-anomer
AM338_01195	COG1085	galactose-1-phosphate uridylyltransferase
AM338_01200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM338_01205	COG1119	ATPase activity
AM338_01210	COG2005	Transcriptional regulator
AM338_01210	COG3585	molybdate ion transport
AM338_01225	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM338_01230	COG4149	molybdate abc transporter
AM338_01235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM338_01240	COG0561	phosphatase activity
AM338_01250	COG0583	DNA-binding transcription factor activity
AM338_01255	COG2828	Protein conserved in bacteria
AM338_01260	COG0471	metal ion transport
AM338_01265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM338_01270	COG4677	pectinesterase activity
AM338_01280	COG1881	PFAM PEBP family protein
AM338_01285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM338_01300	COG2226	methyltransferase
AM338_01305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM338_01315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM338_01325	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM338_01335	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM338_01340	COG0314	molybdopterin synthase activity
AM338_01345	COG0670	Belongs to the BI1 family
AM338_01350	COG0670	Belongs to the BI1 family
AM338_01355	COG0392	lysyltransferase activity
AM338_01360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM338_01365	COG3568	Endonuclease Exonuclease Phosphatase
AM338_01375	COG0842	Transport permease protein
AM338_01380	COG0842	Transport permease protein
AM338_01385	COG1131	(ABC) transporter
AM338_01395	COG1309	transcriptional regulator
AM338_01400	COG0513	Belongs to the DEAD box helicase family
AM338_01405	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM338_01415	COG1199	ATP-dependent helicase activity
AM338_01420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM338_01425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM338_01435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM338_01445	COG4774	siderophore transport
AM338_01460	COG0668	transmembrane transport
AM338_01465	COG1126	abc transporter atp-binding protein
AM338_01470	COG0765	amino acid transport
AM338_01475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_01500	COG5006	permease, DMT superfamily
AM338_01505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM338_01510	COG2194	sulfuric ester hydrolase activity
AM338_01520	COG1321	iron dependent repressor
AM338_01525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM338_01530	COG1376	ErfK ybiS ycfS ynhG family protein
AM338_01535	COG0488	(ABC) transporter
AM338_01545	COG0561	phosphatase activity
AM338_01555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM338_01560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM338_01565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM338_01570	COG0303	'Molybdopterin
AM338_01575	COG1446	asparaginase
AM338_01580	COG4172	Belongs to the ABC transporter superfamily
AM338_01585	COG0747	negative chemotaxis
AM338_01595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM338_01600	COG2200	EAL domain
AM338_01605	COG2199	diguanylate cyclase activity
AM338_01620	COG2133	pyrroloquinoline quinone binding
AM338_01625	COG0625	glutathione transferase activity
AM338_01630	COG1686	Belongs to the peptidase S11 family
AM338_01635	COG1349	DNA-binding transcription factor activity
AM338_01640	COG0671	phosphoesterase, PA-phosphatase related
AM338_01645	COG2814	Major facilitator Superfamily
AM338_01655	COG0561	phosphatase activity
AM338_01660	COG0738	Major facilitator superfamily
AM338_01665	COG3226	Transcriptional regulator
AM338_01680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM338_01690	COG0778	Nitroreductase
AM338_01710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM338_01715	COG3842	ATPase activity
AM338_01720	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM338_01725	COG1177	transmembrane transport
AM338_01740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_01745	COG4160	amino acid transport
AM338_01750	COG4215	(ABC) transporter
AM338_01755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_01760	COG1126	abc transporter atp-binding protein
AM338_01775	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM338_01780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM338_01785	COG0702	epimerase
AM338_01790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM338_01795	COG0028	Belongs to the TPP enzyme family
AM338_01800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_01810	COG2431	L-lysine efflux transmembrane transporter activity
AM338_01820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM338_01825	COG3593	DNA synthesis involved in DNA repair
AM338_01830	COG2990	Protein conserved in bacteria
AM338_01835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_01840	COG1136	(ABC) transporter
AM338_01840	COG0577	efflux transmembrane transporter activity
AM338_01845	COG1278	Cold shock
AM338_01900	COG0740	serine-type endopeptidase activity
AM338_01930	COG0542	response to heat
AM338_01955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM338_01960	COG4988	ABC transporter
AM338_01965	COG0492	ferredoxin-NADP+ reductase activity
AM338_01975	COG1522	sequence-specific DNA binding
AM338_01980	COG1674	ftsk spoiiie
AM338_01980	COG1178	ABC-type Fe3 transport system permease component
AM338_01990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM338_02000	COG0243	molybdopterin cofactor binding
AM338_02005	COG0437	4 iron, 4 sulfur cluster binding
AM338_02010	COG3302	dmso reductase anchor subunit
AM338_02015	COG1335	isochorismatase
AM338_02025	COG0531	amino acid
AM338_02030	COG0583	DNA-binding transcription factor activity
AM338_02035	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM338_02040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM338_02045	COG1882	Formate acetyltransferase
AM338_02050	COG2116	formate transmembrane transporter activity
AM338_02055	COG1944	ATP diphosphatase activity
AM338_02060	COG2323	membrane
AM338_02075	COG0501	Belongs to the peptidase M48B family
AM338_02085	COG0539	negative regulation of cytoplasmic translation
AM338_02095	COG2333	competence protein COMEC
AM338_02095	COG0658	competence protein
AM338_02100	COG1132	(ABC) transporter
AM338_02105	COG1663	tetraacyldisaccharide 4'-kinase activity
AM338_02110	COG3214	Protein conserved in bacteria
AM338_02125	COG3173	Aminoglycoside phosphotransferase
AM338_02130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM338_02140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM338_02150	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM338_02160	COG2989	Protein conserved in bacteria
AM338_02170	COG3108	Peptidase M15
AM338_02175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM338_02185	COG1448	Aminotransferase
AM338_02200	COG3316	Transposase and inactivated derivatives
AM338_02235	COG0308	aminopeptidase N
AM338_02240	COG1116	anion transmembrane transporter activity
AM338_02245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM338_02255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM338_02260	COG0431	NADPH-dependent FMN reductase
AM338_02270	COG3539	Fimbrial protein
AM338_02275	COG3121	Chaperone
AM338_02280	COG3188	usher protein
AM338_02285	COG3539	Fimbrial protein
AM338_02290	COG3539	Fimbrial protein
AM338_02295	COG3539	Fimbrial protein
AM338_02300	COG3121	Chaperone
AM338_02315	COG0633	Ferredoxin
AM338_02315	COG3217	Mosc domain protein beta barrel domain protein
AM338_02325	COG0488	(ABC) transporter
AM338_02330	COG2995	paraquat-inducible protein a
AM338_02335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM338_02335	COG3008	intermembrane lipid transfer
AM338_02340	COG3009	Protein conserved in bacteria
AM338_02345	COG3130	regulation of translation
AM338_02355	COG1067	ATP-dependent peptidase activity
AM338_02365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM338_02365	COG2885	chlorophyll binding
AM338_02380	COG3070	regulator of competence-specific genes
AM338_02385	COG1289	transmembrane transporter activity
AM338_02390	COG3304	Inner membrane component domain
AM338_02395	COG0210	DNA helicase
AM338_02410	COG1832	CoA-binding protein
AM338_02425	COG1254	Belongs to the acylphosphatase family
AM338_02430	COG2920	part of a sulfur-relay system
AM338_02435	COG0670	Belongs to the BI1 family
AM338_02445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM338_02450	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM338_02455	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AM338_02460	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM338_02465	COG1999	signal sequence binding
AM338_02470	COG1773	rubredoxin
AM338_02475	COG1271	oxidase subunit
AM338_02480	COG1294	oxidase, subunit
AM338_02495	COG0489	protein tyrosine kinase activity
AM338_02495	COG3206	protein involved in exopolysaccharide biosynthesis
AM338_02500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM338_02505	COG1596	polysaccharide export
AM338_02510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM338_02530	COG1278	Cold shock
AM338_02535	COG1278	Cold shock
AM338_02555	COG0348	domain, Protein
AM338_02560	COG0784	Response regulator, receiver
AM338_02560	COG2198	Histidine kinase
AM338_02560	COG2205	protein histidine kinase activity
AM338_02565	COG1879	ABC-type sugar transport system periplasmic component
AM338_02570	COG0745	RESPONSE REGULATOR receiver
AM338_02575	COG3005	denitrification pathway
AM338_02580	COG0243	molybdopterin cofactor binding
AM338_02585	COG3381	protein complex oligomerization
AM338_02625	COG3729	General stress protein
AM338_02630	COG2233	PERMEase
AM338_02645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM338_02665	COG1309	transcriptional regulator
AM338_02670	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM338_02670	COG0506	proline dehydrogenase activity
AM338_02670	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM338_02685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM338_02700	COG0672	)-iron permease
AM338_02705	COG2822	iron ion transport
AM338_02710	COG2837	iron assimilation
AM338_02720	COG1702	phosphate starvation-inducible protein PhoH
AM338_02725	COG3658	cytochrome
AM338_02730	COG1215	transferase activity, transferring glycosyl groups
AM338_02735	COG1649	PFAM Uncharacterised BCR, COG1649
AM338_02735	COG0726	polysaccharide deacetylase
AM338_02740	COG0457	Tetratricopeptide repeat
AM338_02745	COG3706	GGDEF domain
AM338_02785	COG3381	protein complex oligomerization
AM338_02795	COG1462	curli production assembly transport component CsgG
AM338_02810	COG2197	response regulator
AM338_02845	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM338_02850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM338_02875	COG2943	transferase activity, transferring hexosyl groups
AM338_02880	COG5645	(Lipo)protein
AM338_02895	COG1560	Kdo2-lipid A biosynthetic process
AM338_02905	COG2353	YceI-like domain
AM338_02910	COG3038	cytochrome b561
AM338_02945	COG2999	glutathione oxidoreductase activity
AM338_02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM338_02965	COG0673	inositol 2-dehydrogenase activity
AM338_02970	COG0728	peptidoglycan biosynthetic process
AM338_02975	COG3418	PFAM FlgN family protein
AM338_02980	COG2747	anti-sigma28 factor FlgM
AM338_02985	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AM338_02990	COG1815	bacterial-type flagellum-dependent cell motility
AM338_02995	COG1558	bacterial-type flagellum-dependent cell motility
AM338_03000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM338_03005	COG1749	Flagellar hook protein flgE
AM338_03010	COG4787	bacterial-type flagellum-dependent cell motility
AM338_03015	COG4786	Flagellar basal body rod
AM338_03030	COG3951	Flagellar rod assembly protein muramidase FlgJ
AM338_03030	COG1705	Flagellar rod assembly protein muramidase FlgJ
AM338_03035	COG1256	bacterial-type flagellum assembly
AM338_03040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM338_03045	COG1530	ribonuclease E activity
AM338_03060	COG0564	pseudouridine synthase activity
AM338_03070	COG1399	metal-binding, possibly nucleic acid-binding protein
AM338_03090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM338_03095	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_03105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM338_03110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM338_03115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM338_03125	COG0470	DNA polymerase III
AM338_03130	COG0084	hydrolase, TatD family'
AM338_03135	COG1263	PTS System
AM338_03135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_03140	COG4773	Receptor
AM338_03145	COG0537	adenosine 5'-monophosphoramidase activity
AM338_03150	COG5633	Lipoprotein
AM338_03155	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM338_03175	COG1252	NADH dehydrogenase
AM338_03185	COG3134	Outer membrane lipoprotein
AM338_03190	COG1309	transcriptional regulator
AM338_03200	COG1376	ErfK ybiS ycfS ynhG family protein
AM338_03200	COG1388	LysM domain
AM338_03205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM338_03210	COG4763	Acyl-transferase
AM338_03215	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM338_03220	COG1136	(ABC) transporter
AM338_03225	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM338_03235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM338_03240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM338_03250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM338_03255	COG1177	transmembrane transport
AM338_03260	COG0582	viral genome integration into host DNA
AM338_03270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM338_03360	COG1403	HNH endonuclease
AM338_03365	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM338_03370	COG0484	heat shock protein binding
AM338_03415	COG3772	lysozyme
AM338_03555	COG3344	reverse transcriptase
AM338_03585	COG0500	methyltransferase
AM338_03595	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM338_03600	COG3842	ATPase activity
AM338_03615	COG2850	peptidyl-arginine hydroxylation
AM338_03620	COG2205	protein histidine kinase activity
AM338_03625	COG0745	RESPONSE REGULATOR receiver
AM338_03630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM338_03650	COG1187	pseudouridine synthase activity
AM338_03655	COG0538	isocitrate dehydrogenase activity
AM338_03665	COG5562	phage envelope protein
AM338_03670	COG0789	Transcriptional regulator
AM338_03675	COG2200	EAL domain
AM338_03700	COG2200	EAL domain
AM338_03755	COG2894	cell division
AM338_03790	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM338_03805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM338_03810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM338_03815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM338_03830	COG2719	SpoVR family
AM338_03840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM338_03850	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM338_03865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM338_03870	COG2261	transglycosylase associated protein
AM338_03890	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM338_03890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM338_03890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_03895	COG1461	Dihydroxyacetone kinase
AM338_03900	COG2376	Dihydroxyacetone kinase
AM338_03905	COG3284	Transcriptional regulator
AM338_03910	COG3468	outer membrane autotransporter barrel domain protein
AM338_03925	COG0012	GTP binding
AM338_03940	COG0659	secondary active sulfate transmembrane transporter activity
AM338_03945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM338_03950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM338_03960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM338_03970	COG2890	protein-(glutamine-N5) methyltransferase activity
AM338_03975	COG3094	Invasion gene expression up-regulator, SirB
AM338_03980	COG2912	Transglutaminase-like superfamily
AM338_04015	COG0387	Pfam Sodium calcium exchanger
AM338_04020	COG4572	Cation transport regulator
AM338_04025	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM338_04030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM338_04035	COG4932	domain protein
AM338_04040	COG2197	response regulator
AM338_04045	COG3850	Histidine kinase
AM338_04055	COG2223	nitrite transmembrane transporter activity
AM338_04060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM338_04065	COG1140	nitrate reductase beta subunit
AM338_04070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM338_04075	COG2181	nitrate reductase activity
AM338_04110	COG0788	formyltetrahydrofolate deformylase activity
AM338_04120	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM338_04125	COG0745	RESPONSE REGULATOR receiver
AM338_04130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM338_04135	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM338_04140	COG1435	thymidine kinase activity
AM338_04150	COG1012	belongs to the aldehyde dehydrogenase family
AM338_04150	COG1454	alcohol dehydrogenase
AM338_04155	COG2095	MarC family integral membrane protein
AM338_04165	COG4166	transmembrane transport
AM338_04170	COG0601	transmembrane transport
AM338_04175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM338_04180	COG0444	Belongs to the ABC transporter superfamily
AM338_04185	COG4608	Belongs to the ABC transporter superfamily
AM338_04205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM338_04210	COG2350	Protein conserved in bacteria
AM338_04215	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM338_04220	COG1607	acyl-coa hydrolase
AM338_04240	COG3047	cAMP biosynthetic process
AM338_04245	COG3685	Protein conserved in bacteria
AM338_04250	COG3685	Protein conserved in bacteria
AM338_04255	COG3729	General stress protein
AM338_04270	COG0134	indole-3-glycerol-phosphate synthase activity
AM338_04270	COG0135	phosphoribosylanthranilate isomerase activity
AM338_04275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM338_04275	COG0512	Glutamine amidotransferase of anthranilate synthase
AM338_04280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM338_04290	COG0613	PHP domain protein
AM338_04295	COG0009	L-threonylcarbamoyladenylate synthase
AM338_04300	COG4907	membrane protein (DUF2207)
AM338_04305	COG1187	pseudouridine synthase activity
AM338_04310	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM338_04315	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_04320	COG0616	signal peptide processing
AM338_04335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM338_04345	COG0583	DNA-binding transcription factor activity
AM338_04375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM338_04385	COG0671	phosphoesterase, PA-phosphatase related
AM338_04390	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM338_04395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM338_04405	COG0023	Translation Initiation Factor
AM338_04415	COG1349	DNA-binding transcription factor activity
AM338_04425	COG5001	Diguanylate cyclase
AM338_04440	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM338_04440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM338_04445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM338_04450	COG2852	Protein conserved in bacteria
AM338_04455	COG4172	Belongs to the ABC transporter superfamily
AM338_04460	COG4172	Belongs to the ABC transporter superfamily
AM338_04465	COG4171	peptide transport system, permease
AM338_04470	COG4168	peptide transport system, permease
AM338_04475	COG4166	transmembrane transport
AM338_04490	COG0531	amino acid
AM338_04495	COG0174	glutamine synthetase
AM338_04500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM338_04505	COG1917	Cupin 2, conserved barrel domain protein
AM338_04505	COG1396	sequence-specific DNA binding
AM338_04515	COG1012	belongs to the aldehyde dehydrogenase family
AM338_04520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM338_04525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM338_04530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM338_04535	COG1842	Phage shock protein A
AM338_04545	COG1983	PspC domain protein
AM338_04555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM338_04560	COG0366	Alpha amylase catalytic
AM338_04570	COG1175	transmembrane transport
AM338_04575	COG0395	ABC-type sugar transport system, permease component
AM338_04580	COG1063	alcohol dehydrogenase
AM338_04585	COG1082	Xylose isomerase domain protein TIM barrel
AM338_04590	COG0673	inositol 2-dehydrogenase activity
AM338_04595	COG1554	hydrolase, family 65, central catalytic
AM338_04600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_04605	COG3842	ATPase activity
AM338_04615	COG1609	Transcriptional regulator
AM338_04620	COG3106	COG3106 Predicted ATPase
AM338_04630	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AM338_04635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM338_04640	COG4948	Mandelate Racemase Muconate Lactonizing
AM338_04645	COG2866	Carboxypeptidase
AM338_04650	COG0702	epimerase
AM338_04655	COG1073	alpha beta
AM338_04660	COG0583	DNA-binding transcription factor activity
AM338_04670	COG4166	transmembrane transport
AM338_04675	COG0668	transmembrane transport
AM338_04680	COG3182	Iron-regulated membrane protein
AM338_04685	COG0589	response to stress
AM338_04690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM338_04695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM338_04700	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM338_04710	COG1473	amidohydrolase
AM338_04715	COG1473	amidohydrolase
AM338_04720	COG0583	DNA-binding transcription factor activity
AM338_04730	COG2840	Smr protein MutS2
AM338_04735	COG3706	GGDEF domain
AM338_04750	COG0513	Belongs to the DEAD box helicase family
AM338_04760	COG0589	response to stress
AM338_04765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM338_04775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM338_04775	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM338_04775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM338_04775	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM338_04780	COG3042	response to heat
AM338_04785	COG3187	Heat shock protein
AM338_04790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM338_04795	COG2911	Protein conserved in bacteria
AM338_04805	COG3784	Protein of unknown function (DUF1318)
AM338_04810	COG2207	Transcriptional regulator
AM338_04815	COG1012	belongs to the aldehyde dehydrogenase family
AM338_04820	COG3733	amine oxidase
AM338_04825	COG1012	belongs to the aldehyde dehydrogenase family
AM338_04825	COG2030	dehydratase
AM338_04830	COG3396	Phenylacetate-CoA oxygenase
AM338_04835	COG3460	Phenylacetate-CoA oxygenase
AM338_04840	COG3396	Phenylacetate-CoA oxygenase
AM338_04845	COG2151	metal-sulfur cluster biosynthetic enzyme
AM338_04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_04855	COG1024	Enoyl-CoA hydratase
AM338_04860	COG1024	Enoyl-CoA hydratase
AM338_04865	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM338_04870	COG2050	protein possibly involved in aromatic compounds catabolism
AM338_04875	COG0183	Belongs to the thiolase family
AM338_04880	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM338_04885	COG3327	negative regulation of DNA-templated transcription, initiation
AM338_04890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM338_04920	COG0667	Aldo Keto reductase
AM338_04930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM338_04935	COG4589	Belongs to the CDS family
AM338_04940	COG2267	carboxylic ester hydrolase activity
AM338_04945	COG2453	phosphatase
AM338_04945	COG0671	phosphoesterase, PA-phosphatase related
AM338_04955	COG1643	Atp-dependent helicase
AM338_04960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM338_04965	COG1012	belongs to the aldehyde dehydrogenase family
AM338_04980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM338_04985	COG3038	cytochrome b561
AM338_05000	COG0840	transmembrane signaling receptor activity
AM338_05005	COG0583	DNA-binding transcription factor activity
AM338_05010	COG5383	Protein conserved in bacteria
AM338_05030	COG2841	Protein conserved in bacteria
AM338_05035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM338_05040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM338_05045	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM338_05050	COG0500	methyltransferase
AM338_05065	COG0675	Transposase, IS605 OrfB family
AM338_05070	COG3135	benzoate transporter
AM338_05075	COG1396	sequence-specific DNA binding
AM338_05080	COG0826	peptidase U32
AM338_05090	COG1724	mRNA binding
AM338_05095	COG1598	PFAM Uncharacterised protein family UPF0150
AM338_05100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM338_05105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM338_05110	COG3842	ATPase activity
AM338_05115	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM338_05120	COG1177	transmembrane transport
AM338_05150	COG3238	Protein conserved in bacteria
AM338_05155	COG1247	-acetyltransferase
AM338_05165	COG2130	NADP-dependent
AM338_05170	COG1802	Transcriptional regulator
AM338_05175	COG4772	TonB-dependent receptor
AM338_05190	COG3391	amine dehydrogenase activity
AM338_05195	COG1113	amino acid transport
AM338_05200	COG0625	glutathione transferase activity
AM338_05210	COG3501	Rhs element vgr protein
AM338_05215	COG3209	COG3209 Rhs family protein
AM338_05230	COG5433	transposase activity
AM338_05240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM338_05245	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM338_05250	COG0384	phenazine biosynthesis protein PhzF
AM338_05255	COG2181	nitrate reductase activity
AM338_05260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM338_05265	COG1140	nitrate reductase beta subunit
AM338_05275	COG2223	nitrite transmembrane transporter activity
AM338_05290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM338_05295	COG0697	spore germination
AM338_05300	COG0243	molybdopterin cofactor binding
AM338_05300	COG3383	formate dehydrogenase (NAD+) activity
AM338_05305	COG3383	formate dehydrogenase (NAD+) activity
AM338_05305	COG0243	molybdopterin cofactor binding
AM338_05310	COG0437	4 iron, 4 sulfur cluster binding
AM338_05315	COG2864	formate dehydrogenase
AM338_05320	COG3093	addiction module antidote protein HigA
AM338_05325	COG1064	alcohol dehydrogenase
AM338_05350	COG1764	response to oxidative stress
AM338_05355	COG4608	Belongs to the ABC transporter superfamily
AM338_05360	COG0444	Belongs to the ABC transporter superfamily
AM338_05365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM338_05370	COG0601	transmembrane transport
AM338_05375	COG0747	negative chemotaxis
AM338_05380	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM338_05385	COG2200	EAL domain
AM338_05385	COG2202	Pas domain
AM338_05385	COG2199	diguanylate cyclase activity
AM338_05390	COG3706	GGDEF domain
AM338_05400	COG0531	amino acid
AM338_05405	COG0076	glutamate decarboxylase activity
AM338_05410	COG0612	Peptidase, M16
AM338_05415	COG4771	TonB-dependent receptor
AM338_05420	COG4178	(ABC) transporter
AM338_05425	COG0641	radical SAM
AM338_05430	COG3119	arylsulfatase activity
AM338_05435	COG2207	Transcriptional regulator
AM338_05445	COG0243	molybdopterin cofactor binding
AM338_05450	COG3539	Fimbrial protein
AM338_05455	COG3539	Fimbrial protein
AM338_05460	COG3539	Fimbrial protein
AM338_05465	COG3188	usher protein
AM338_05475	COG3550	peptidyl-serine autophosphorylation
AM338_05480	COG1396	sequence-specific DNA binding
AM338_05530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM338_05540	COG3781	membrane
AM338_05550	COG0246	Mannitol dehydrogenase
AM338_05560	COG2199	diguanylate cyclase activity
AM338_05570	COG2066	Belongs to the glutaminase family
AM338_05575	COG1012	belongs to the aldehyde dehydrogenase family
AM338_05580	COG0583	DNA-binding transcription factor activity
AM338_05600	COG1846	Transcriptional regulator
AM338_05605	COG4977	sequence-specific DNA binding
AM338_05615	COG0697	spore germination
AM338_05620	COG2814	Major facilitator Superfamily
AM338_05630	COG3706	GGDEF domain
AM338_05635	COG3111	PFAM Bacterial OB fold (BOF) protein
AM338_05640	COG1546	Belongs to the CinA family
AM338_05645	COG0339	signal peptide processing
AM338_05655	COG4221	oxidoreductase activity
AM338_05660	COG1802	Transcriptional regulator
AM338_05670	COG0246	Mannitol dehydrogenase
AM338_05675	COG0477	Major facilitator Superfamily
AM338_05680	COG1063	alcohol dehydrogenase
AM338_05685	COG4948	Mandelate Racemase Muconate Lactonizing
AM338_05705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM338_05720	COG0243	molybdopterin cofactor binding
AM338_05725	COG0243	molybdopterin cofactor binding
AM338_05730	COG0437	4 iron, 4 sulfur cluster binding
AM338_05735	COG3302	dmso reductase anchor subunit
AM338_05740	COG3381	protein complex oligomerization
AM338_05750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM338_05755	COG1940	carbohydrate kinase activity
AM338_05760	COG0583	DNA-binding transcription factor activity
AM338_05765	COG2814	Major facilitator Superfamily
AM338_05785	COG3591	Belongs to the peptidase S1B family
AM338_05805	COG0628	permease
AM338_05810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM338_05815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM338_05830	COG0531	amino acid
AM338_05835	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_05840	COG3136	membrane protein required for alginate biosynthesis
AM338_05845	COG0745	RESPONSE REGULATOR receiver
AM338_05850	COG2205	protein histidine kinase activity
AM338_05860	COG0114	fumarate hydratase activity
AM338_05865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM338_05865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM338_05870	COG1482	cell wall glycoprotein biosynthetic process
AM338_05875	COG5339	Protein conserved in bacteria
AM338_05890	COG3250	beta-galactosidase activity
AM338_05895	COG1309	transcriptional regulator
AM338_05900	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_05905	COG1609	Transcriptional regulator
AM338_05910	COG1263	PTS System
AM338_05910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_05915	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM338_05925	COG0673	inositol 2-dehydrogenase activity
AM338_05970	COG4659	FMN binding
AM338_05980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM338_05990	COG3104	oligopeptide transport
AM338_05995	COG0625	glutathione transferase activity
AM338_06000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM338_06015	COG3895	Periplasmic Protein
AM338_06025	COG3133	Outer membrane lipoprotein
AM338_06040	COG1566	PFAM secretion protein HlyD family protein
AM338_06045	COG1289	transmembrane transporter activity
AM338_06050	COG2032	superoxide dismutase activity
AM338_06055	COG4989	oxidoreductase activity
AM338_06060	COG3313	Fe-S protein
AM338_06065	COG1309	transcriptional regulator
AM338_06070	COG1902	pentaerythritol trinitrate reductase activity
AM338_06075	COG0346	lactoylglutathione lyase activity
AM338_06080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM338_06085	COG1201	RNA secondary structure unwinding
AM338_06090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM338_06095	COG0791	NLP P60 protein
AM338_06100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM338_06105	COG2814	Major facilitator Superfamily
AM338_06125	COG0583	DNA-binding transcription factor activity
AM338_06130	COG2814	Major facilitator Superfamily
AM338_06135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM338_06140	COG0307	riboflavin synthase, alpha
AM338_06150	COG3468	outer membrane autotransporter barrel domain protein
AM338_06170	COG4529	Protein conserved in bacteria
AM338_06180	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM338_06185	COG0437	4 iron, 4 sulfur cluster binding
AM338_06195	COG2414	aldehyde ferredoxin oxidoreductase
AM338_06200	COG0437	4 iron, 4 sulfur cluster binding
AM338_06210	COG0469	pyruvate kinase activity
AM338_06215	COG4238	major outer membrane lipoprotein
AM338_06220	COG1376	ErfK ybiS ycfS ynhG family protein
AM338_06235	COG0719	Fe-S assembly protein
AM338_06240	COG0396	ATPase activity
AM338_06245	COG0719	Fe-S assembly protein
AM338_06250	COG0316	Belongs to the HesB IscA family
AM338_06260	COG2050	protein possibly involved in aromatic compounds catabolism
AM338_06265	COG0277	FAD linked oxidase domain protein
AM338_06265	COG0247	lactate metabolic process
AM338_06275	COG0628	permease
AM338_06290	COG0738	Major facilitator superfamily
AM338_06295	COG2271	Major facilitator Superfamily
AM338_06310	COG4670	ketone body catabolic process
AM338_06315	COG1960	acyl-CoA dehydrogenase activity
AM338_06320	COG1917	Cupin 2, conserved barrel domain protein
AM338_06320	COG2207	Transcriptional regulator
AM338_06330	COG2086	electron transfer activity
AM338_06335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM338_06340	COG0644	oxidoreductase
AM338_06345	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM338_06350	COG0318	PFAM AMP-dependent synthetase and ligase
AM338_06355	COG0574	Belongs to the PEP-utilizing enzyme family
AM338_06355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM338_06370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM338_06375	COG4256	Hemin uptake protein
AM338_06385	COG2200	EAL domain
AM338_06390	COG0791	NLP P60 protein
AM338_06400	COG0386	Belongs to the glutathione peroxidase family
AM338_06415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM338_06415	COG0072	phenylalanine-tRNA ligase activity
AM338_06460	COG3137	Salt-induced outer membrane protein
AM338_06465	COG1105	Belongs to the carbohydrate kinase PfkB family
AM338_06485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_06490	COG1988	membrane-bound metal-dependent
AM338_06510	COG0753	catalase activity
AM338_06520	COG1486	melibiose metabolic process
AM338_06525	COG1917	Cupin 2, conserved barrel domain protein
AM338_06525	COG2169	Transcriptional regulator
AM338_06530	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM338_06535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM338_06540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM338_06550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM338_06560	COG0322	excinuclease ABC activity
AM338_06570	COG3678	ATP-independent chaperone mediated protein folding
AM338_06590	COG3138	arginine N-succinyltransferase
AM338_06605	COG0708	Exodeoxyribonuclease III
AM338_06610	COG0398	Pfam SNARE associated Golgi protein
AM338_06620	COG0398	Pfam SNARE associated Golgi protein
AM338_06625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM338_06630	COG4134	Bacterial extracellular solute-binding protein
AM338_06635	COG4135	transport system, permease component
AM338_06640	COG4136	ATPase activity
AM338_06645	COG2897	thiosulfate sulfurtransferase activity
AM338_06650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM338_06655	COG0494	nUDIX hydrolase
AM338_06665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM338_06675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM338_06690	COG0778	Nitroreductase
AM338_06700	COG0616	signal peptide processing
AM338_06705	COG0252	asparaginase activity
AM338_06710	COG1335	isochorismatase
AM338_06715	COG2814	Major facilitator Superfamily
AM338_06720	COG1349	DNA-binding transcription factor activity
AM338_06725	COG0667	Aldo Keto reductase
AM338_06730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_06735	COG0191	fructose-bisphosphate aldolase activity
AM338_06740	COG1063	alcohol dehydrogenase
AM338_06745	COG2271	Major facilitator Superfamily
AM338_06750	COG1063	alcohol dehydrogenase
AM338_06755	COG3139	Protein of unknown function (DUF1315)
AM338_06765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM338_06770	COG0676	glucose-6-phosphate 1-epimerase activity
AM338_06775	COG0656	L-ascorbic acid biosynthetic process
AM338_06780	COG3713	MltA-interacting MipA family protein
AM338_06785	COG2766	serine protein kinase
AM338_06795	COG2199	diguanylate cyclase activity
AM338_06800	COG2199	diguanylate cyclase activity
AM338_06805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM338_06820	COG2207	Transcriptional regulator
AM338_06825	COG2807	transmembrane transport
AM338_06830	COG3189	MarR family transcriptional regulator
AM338_06835	COG3042	response to heat
AM338_06840	COG2199	diguanylate cyclase activity
AM338_06840	COG2203	Gaf domain
AM338_06855	COG2261	transglycosylase associated protein
AM338_06865	COG3615	Tellurite resistance protein tehB
AM338_06875	COG0583	DNA-binding transcription factor activity
AM338_06880	COG0473	3-isopropylmalate dehydrogenase activity
AM338_06885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM338_06890	COG4638	Rieske (2fe-2S)
AM338_06895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_06900	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM338_06905	COG0318	PFAM AMP-dependent synthetase and ligase
AM338_06910	COG3065	identical protein binding
AM338_06915	COG1214	PFAM Peptidase M22, glycoprotease
AM338_06920	COG1199	ATP-dependent helicase activity
AM338_06925	COG0251	oxidation-reduction process
AM338_06940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM338_06950	COG1760	l-serine dehydratase
AM338_06960	COG1253	flavin adenine dinucleotide binding
AM338_06975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_06975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_06980	COG3715	PTS system
AM338_06985	COG3716	PTS system mannose fructose sorbose family IID component
AM338_07005	COG2226	methyltransferase
AM338_07010	COG1278	Cold shock
AM338_07040	COG1414	Transcriptional regulator
AM338_07045	COG2814	Major facilitator Superfamily
AM338_07055	COG0793	Belongs to the peptidase S41A family
AM338_07065	COG1956	GAF domain-containing protein
AM338_07070	COG2995	paraquat-inducible protein a
AM338_07075	COG3008	intermembrane lipid transfer
AM338_07095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM338_07105	COG1276	copper resistance
AM338_07110	COG2372	response to copper ion
AM338_07120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM338_07125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM338_07130	COG1770	oligopeptidase
AM338_07135	COG2979	Protein of unknown function (DUF533)
AM338_07145	COG3141	response to X-ray
AM338_07155	COG0800	Aldolase
AM338_07160	COG0129	dihydroxy-acid dehydratase activity
AM338_07165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM338_07170	COG1737	Transcriptional regulator
AM338_07175	COG0469	pyruvate kinase activity
AM338_07180	COG1560	Kdo2-lipid A biosynthetic process
AM338_07185	COG0739	heme binding
AM338_07190	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM338_07195	COG1121	(ABC) transporter
AM338_07200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM338_07230	COG0217	transcriptional regulatory protein
AM338_07235	COG0494	nUDIX hydrolase
AM338_07245	COG1335	isochorismatase
AM338_07250	COG1801	Protein of unknown function DUF72
AM338_07255	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM338_07270	COG0243	molybdopterin cofactor binding
AM338_07275	COG3005	denitrification pathway
AM338_07285	COG3102	Protein conserved in bacteria
AM338_07300	COG3755	Protein conserved in bacteria
AM338_07310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM338_07315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM338_07320	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM338_07325	COG0745	RESPONSE REGULATOR receiver
AM338_07330	COG2201	protein-glutamate methylesterase activity
AM338_07335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM338_07340	COG0840	transmembrane signaling receptor activity
AM338_07345	COG0840	transmembrane signaling receptor activity
AM338_07350	COG0835	chemotaxis
AM338_07355	COG0643	Histidine kinase
AM338_07355	COG2198	Histidine kinase
AM338_07360	COG1360	Flagellar Motor Protein
AM338_07365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AM338_07380	COG0589	response to stress
AM338_07390	COG1877	trehalose-phosphatase activity
AM338_07395	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_07400	COG1129	ABC transporter
AM338_07405	COG1879	ABC-type sugar transport system periplasmic component
AM338_07415	COG1528	Iron-storage protein
AM338_07435	COG1528	Iron-storage protein
AM338_07445	COG0814	amino acid
AM338_07450	COG3012	SEC-C Motif Domain Protein
AM338_07450	COG3318	Belongs to the UPF0149 family
AM338_07470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM338_07480	COG2197	response regulator
AM338_07495	COG2197	response regulator
AM338_07525	COG1191	sigma factor activity
AM338_07540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AM338_07545	COG1516	flagellar protein fliS
AM338_07555	COG0366	Alpha amylase catalytic
AM338_07570	COG2391	methyltransferase activity
AM338_07575	COG0425	Belongs to the sulfur carrier protein TusA family
AM338_07580	COG2135	peptidase activity
AM338_07605	COG1766	The M ring may be actively involved in energy transduction
AM338_07610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM338_07615	COG1317	bacterial-type flagellum organization
AM338_07620	COG1157	protein secretion by the type III secretion system
AM338_07625	COG2882	bacterial-type flagellum organization
AM338_07630	COG3144	bacterial-type flagellum assembly
AM338_07635	COG1580	Controls the rotational direction of flagella during chemotaxis
AM338_07640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM338_07645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM338_07650	COG3190	flagellar
AM338_07655	COG1338	Plays a role in the flagellum-specific transport system
AM338_07660	COG1987	bacterial-type flagellum assembly
AM338_07665	COG1684	flagellar biosynthetic protein fliR
AM338_07670	COG2197	response regulator
AM338_07705	COG5475	Uncharacterized small protein (DUF2158)
AM338_07710	COG2354	Protein conserved in bacteria
AM338_07715	COG0697	spore germination
AM338_07720	COG3727	T/G mismatch-specific endonuclease activity
AM338_07725	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM338_07730	COG1418	mRNA catabolic process
AM338_07740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM338_07755	COG2205	protein histidine kinase activity
AM338_07760	COG0745	RESPONSE REGULATOR receiver
AM338_07765	COG2351	hydroxyisourate hydrolase activity
AM338_07780	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM338_07785	COG3038	cytochrome b561
AM338_07810	COG1388	LysM domain
AM338_07810	COG1470	cell adhesion involved in biofilm formation
AM338_07820	COG0477	Major facilitator Superfamily
AM338_07825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM338_07845	COG0534	Mate efflux family protein
AM338_07855	COG0583	DNA-binding transcription factor activity
AM338_07860	COG0583	DNA-binding transcription factor activity
AM338_07870	COG0582	viral genome integration into host DNA
AM338_07875	COG1169	isochorismate synthase
AM338_07880	COG2814	Major facilitator Superfamily
AM338_07885	COG1132	(ABC) transporter
AM338_07900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM338_07900	COG3433	isochorismatase activity
AM338_07900	COG2226	methyltransferase
AM338_07920	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM338_07925	COG4771	TonB-dependent receptor
AM338_08000	COG3504	Conjugal transfer protein
AM338_08055	COG2003	Belongs to the UPF0758 family
AM338_08135	COG1376	ErfK ybiS ycfS ynhG family protein
AM338_08150	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AM338_08185	COG2003	Belongs to the UPF0758 family
AM338_08215	COG4917	ethanolamine utilization protein
AM338_08225	COG1289	transmembrane transporter activity
AM338_08230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM338_08240	COG1686	Belongs to the peptidase S11 family
AM338_08245	COG2925	Exonuclease
AM338_08250	COG0425	Belongs to the sulfur carrier protein TusA family
AM338_08255	COG2391	methyltransferase activity
AM338_08260	COG0531	amino acid
AM338_08265	COG0583	DNA-binding transcription factor activity
AM338_08270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM338_08275	COG4115	mRNA cleavage
AM338_08280	COG2161	toxin-antitoxin pair type II binding
AM338_08300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM338_08310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM338_08310	COG0131	Imidazoleglycerol-phosphate dehydratase
AM338_08315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM338_08330	COG0140	phosphoribosyl-ATP diphosphatase activity
AM338_08330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM338_08340	COG0438	transferase activity, transferring glycosyl groups
AM338_08400	COG1088	dTDP-glucose 4,6-dehydratase activity
AM338_08495	COG1253	flavin adenine dinucleotide binding
AM338_08510	COG2982	Protein involved in outer membrane biogenesis
AM338_08520	COG0572	uridine kinase
AM338_08525	COG5002	protein histidine kinase activity
AM338_08525	COG5001	Diguanylate cyclase
AM338_08525	COG3447	MASE1 domain protein
AM338_08530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM338_08535	COG0443	Heat shock 70 kDa protein
AM338_08540	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
AM338_08545	COG3779	Protein conserved in bacteria
AM338_08550	COG0631	protein serine/threonine phosphatase activity
AM338_08555	COG4245	von Willebrand factor, type A
AM338_08585	COG2205	protein histidine kinase activity
AM338_08590	COG0745	RESPONSE REGULATOR receiver
AM338_08620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_08630	COG1070	Carbohydrate kinase
AM338_08655	COG1069	ribulokinase activity
AM338_08665	COG1830	Aldolase
AM338_08670	COG2211	Major facilitator Superfamily
AM338_08675	COG1397	ADP-ribosylglycohydrolase
AM338_08680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_08685	COG2188	Transcriptional regulator
AM338_08690	COG3757	hydrolase, family 25
AM338_08695	COG0351	phosphomethylpyrimidine kinase
AM338_08715	COG5455	response to cobalt ion
AM338_08720	COG3539	Fimbrial protein
AM338_08725	COG3188	usher protein
AM338_08730	COG3121	Chaperone
AM338_08735	COG3539	Fimbrial protein
AM338_08750	COG0489	protein tyrosine kinase activity
AM338_08765	COG3831	ATPase activity
AM338_08775	COG0714	Associated with various cellular activities
AM338_08780	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM338_08785	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM338_08790	COG4715	Zinc finger, swim domain protein
AM338_08795	COG4808	Protein conserved in bacteria
AM338_08800	COG4807	Protein conserved in bacteria
AM338_08805	COG3279	Response regulator of the LytR AlgR family
AM338_08810	COG3275	phosphorelay sensor kinase activity
AM338_08815	COG0789	Transcriptional regulator
AM338_08825	COG1174	glycine betaine transport
AM338_08830	COG1125	glycine betaine transport
AM338_08835	COG1174	glycine betaine transport
AM338_08840	COG1732	Glycine betaine
AM338_08845	COG1472	Belongs to the glycosyl hydrolase 3 family
AM338_08850	COG0277	FAD linked oxidase domain protein
AM338_08855	COG1686	Belongs to the peptidase S11 family
AM338_08865	COG0586	Pfam SNARE associated Golgi protein
AM338_08870	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_08895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM338_08905	COG1346	cytolysis
AM338_08915	COG2949	membrane
AM338_08925	COG0493	'glutamate synthase
AM338_08930	COG0167	dihydroorotate dehydrogenase activity
AM338_08930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM338_08935	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM338_08940	COG1129	ABC transporter
AM338_08945	COG1879	ABC-type sugar transport system periplasmic component
AM338_08950	COG1609	Transcriptional regulator
AM338_08960	COG2311	Membrane
AM338_08985	COG4771	TonB-dependent receptor
AM338_08995	COG0833	amino acid
AM338_09005	COG0583	DNA-binding transcription factor activity
AM338_09010	COG2855	membrane
AM338_09015	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM338_09020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_09020	COG1522	sequence-specific DNA binding
AM338_09025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM338_09035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM338_09040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM338_09045	COG2313	pseudouridylate synthase activity
AM338_09050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_09055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_09055	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM338_09055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_09060	COG1105	Belongs to the carbohydrate kinase PfkB family
AM338_09065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_09065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_09070	COG2814	Major facilitator Superfamily
AM338_09085	COG0246	Mannitol dehydrogenase
AM338_09090	COG0523	cobalamin synthesis protein
AM338_09095	COG0671	phosphoesterase, PA-phosphatase related
AM338_09100	COG0791	NLP P60 protein
AM338_09105	COG2200	EAL domain
AM338_09110	COG4166	transmembrane transport
AM338_09115	COG4174	ABC transporter (Permease)
AM338_09120	COG4239	(ABC) transporter, permease
AM338_09125	COG4172	Belongs to the ABC transporter superfamily
AM338_09140	COG2814	Major facilitator Superfamily
AM338_09145	COG1187	pseudouridine synthase activity
AM338_09155	COG1061	Type III restriction enzyme res subunit
AM338_09175	COG3083	sulfuric ester hydrolase activity
AM338_09190	COG3468	outer membrane autotransporter barrel domain protein
AM338_09200	COG2197	response regulator
AM338_09205	COG4235	cytochrome complex assembly
AM338_09205	COG3088	subunit of a heme lyase
AM338_09210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM338_09215	COG1138	Cytochrome C-type biogenesis protein
AM338_09225	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM338_09230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM338_09235	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM338_09245	COG3005	denitrification pathway
AM338_09250	COG3043	anaerobic respiration
AM338_09255	COG0348	domain, Protein
AM338_09260	COG0437	4 iron, 4 sulfur cluster binding
AM338_09270	COG3062	negative regulation of establishment of protein localization
AM338_09275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_09275	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_09295	COG4615	Cyclic peptide transporter
AM338_09300	COG3145	DNA-N1-methyladenine dioxygenase activity
AM338_09305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM338_09305	COG2169	Transcriptional regulator
AM338_09310	COG1477	protein flavinylation
AM338_09315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM338_09330	COG2198	Histidine kinase
AM338_09330	COG0642	Histidine kinase
AM338_09335	COG2197	response regulator
AM338_09340	COG0784	Response regulator, receiver
AM338_09340	COG2205	protein histidine kinase activity
AM338_09345	COG3852	Histidine kinase
AM338_09350	COG2204	response regulator
AM338_09355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM338_09360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM338_09365	COG2031	fatty acid transporter
AM338_09370	COG0183	Belongs to the thiolase family
AM338_09375	COG4676	Protein conserved in bacteria
AM338_09380	COG5445	Predicted secreted protein (DUF2300)
AM338_09385	COG2373	Large extracellular alpha-helical protein
AM338_09390	COG3234	Protein of unknown function (DUF1175)
AM338_09395	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AM338_09400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM338_09410	COG3468	outer membrane autotransporter barrel domain protein
AM338_09420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM338_09425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM338_09430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_09435	COG3642	lipopolysaccharide core region biosynthetic process
AM338_09440	COG0583	DNA-binding transcription factor activity
AM338_09445	COG0584	glycerophosphoryl diester phosphodiesterase
AM338_09450	COG2271	Major facilitator Superfamily
AM338_09455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM338_09465	COG0247	lactate metabolic process
AM338_09470	COG5464	transposase or invertase
AM338_09485	COG2271	Major facilitator Superfamily
AM338_09495	COG1414	Transcriptional regulator
AM338_09500	COG1414	Transcriptional regulator
AM338_09565	COG0318	PFAM AMP-dependent synthetase and ligase
AM338_09575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM338_09590	COG1169	isochorismate synthase
AM338_09595	COG4575	ribosome binding
AM338_09600	COG2153	protein acetylation
AM338_09610	COG5160	protein modification by small protein removal
AM338_09615	COG2304	oxidoreductase activity
AM338_09620	COG2234	aminopeptidase activity
AM338_09640	COG0457	Tetratricopeptide repeat
AM338_09650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM338_09655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM338_09665	COG0839	Belongs to the complex I subunit 6 family
AM338_09670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM338_09680	COG1034	ATP synthesis coupled electron transport
AM338_09685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM338_09690	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AM338_09710	COG0583	DNA-binding transcription factor activity
AM338_09720	COG0436	Aminotransferase
AM338_09730	COG0471	metal ion transport
AM338_09730	COG0490	domain, Protein
AM338_09735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_09750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM338_09755	COG0280	phosphate acetyltransferase
AM338_09755	COG0857	belongs to the CobB CobQ family
AM338_09760	COG1288	antiporter activity
AM338_09765	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM338_09770	COG0622	Phosphoesterase
AM338_09775	COG0625	glutathione transferase activity
AM338_09780	COG0625	glutathione transferase activity
AM338_09785	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM338_09790	COG1090	epimerase
AM338_09795	COG5464	transposase or invertase
AM338_09800	COG4598	ABC transporter
AM338_09805	COG4160	amino acid transport
AM338_09810	COG4215	(ABC) transporter
AM338_09815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_09820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_09825	COG0163	prenyltransferase activity
AM338_09830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM338_09835	COG1286	toxin biosynthetic process
AM338_09840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM338_09845	COG0285	dihydrofolate synthase activity
AM338_09855	COG0586	Pfam SNARE associated Golgi protein
AM338_09865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM338_09880	COG2814	Major facilitator Superfamily
AM338_09890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM338_09905	COG3101	peptidyl-lysine hydroxylation
AM338_09910	COG0730	response to heat
AM338_09925	COG2890	protein-(glutamine-N5) methyltransferase activity
AM338_09940	COG3539	Fimbrial protein
AM338_09945	COG3539	Fimbrial protein
AM338_09950	COG3539	Fimbrial protein
AM338_09955	COG3121	Chaperone
AM338_09960	COG3188	usher protein
AM338_09965	COG3539	Fimbrial protein
AM338_09970	COG2062	phosphohistidine phosphatase, SixA
AM338_09985	COG3691	Protein conserved in bacteria
AM338_09995	COG2067	long-chain fatty acid transport protein
AM338_10010	COG2853	Lipoprotein
AM338_10020	COG2116	formate transmembrane transporter activity
AM338_10060	COG0477	Major facilitator Superfamily
AM338_10065	COG1566	PFAM secretion protein HlyD family protein
AM338_10070	COG2197	response regulator
AM338_10075	COG0784	Response regulator, receiver
AM338_10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_10075	COG2198	Histidine kinase
AM338_10075	COG2205	protein histidine kinase activity
AM338_10080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM338_10085	COG0679	Auxin Efflux Carrier
AM338_10090	COG0028	Belongs to the TPP enzyme family
AM338_10115	COG1560	Kdo2-lipid A biosynthetic process
AM338_10120	COG0436	Aminotransferase
AM338_10125	COG3275	phosphorelay sensor kinase activity
AM338_10130	COG3279	Response regulator of the LytR AlgR family
AM338_10140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_10140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM338_10140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_10145	COG1363	Peptidase, m42
AM338_10150	COG0006	proline dipeptidase activity
AM338_10155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_10160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_10170	COG0038	chloride channel
AM338_10185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM338_10190	COG3385	transposase activity
AM338_10195	COG2200	EAL domain
AM338_10195	COG2199	diguanylate cyclase activity
AM338_10210	COG3415	Transposase
AM338_10215	COG3415	Transposase
AM338_10245	COG0583	DNA-binding transcription factor activity
AM338_10255	COG2211	Major facilitator Superfamily
AM338_10260	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM338_10270	COG0583	DNA-binding transcription factor activity
AM338_10275	COG0385	Bile acid
AM338_10280	COG3530	Putative quorum-sensing-regulated virulence factor
AM338_10300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM338_10305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_10310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM338_10315	COG2190	(PTS) system
AM338_10330	COG4884	unkown
AM338_10330	COG3831	ATPase activity
AM338_10335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM338_10340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM338_10345	COG4208	sulfate ABC transporter
AM338_10350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM338_10355	COG4150	thiosulfate binding
AM338_10365	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_10380	COG1263	PTS System
AM338_10380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_10385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM338_10390	COG2837	iron assimilation
AM338_10405	COG0456	acetyltransferase
AM338_10410	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM338_10420	COG2207	Transcriptional regulator
AM338_10425	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM338_10430	COG4816	utilization protein
AM338_10440	COG4303	Ethanolamine ammonia lyase large subunit
AM338_10445	COG4819	ethanolamine utilization protein
AM338_10450	COG3192	ethanolamine utilization protein
AM338_10455	COG1454	alcohol dehydrogenase
AM338_10460	COG4820	ethanolamine utilization protein (EutJ)
AM338_10465	COG1012	belongs to the aldehyde dehydrogenase family
AM338_10470	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM338_10475	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM338_10480	COG0280	phosphate acetyltransferase
AM338_10485	COG4812	Cobalamin adenosyltransferase
AM338_10490	COG4766	ethanolamine catabolic process
AM338_10495	COG4917	ethanolamine utilization protein
AM338_10500	COG4810	utilization protein
AM338_10505	COG0281	malic enzyme
AM338_10505	COG0280	phosphate acetyltransferase
AM338_10515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM338_10520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM338_10525	COG5342	invasion associated locus B
AM338_10535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_10535	COG0493	'glutamate synthase
AM338_10540	COG3850	Histidine kinase
AM338_10545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM338_10550	COG1393	Belongs to the ArsC family
AM338_10565	COG0400	carboxylic ester hydrolase activity
AM338_10570	COG1444	tRNA N-acetyltransferase activity
AM338_10575	COG2321	neutral zinc metallopeptidase
AM338_10585	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM338_10595	COG2716	regulation of RNA biosynthetic process
AM338_10600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM338_10605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_10610	COG0651	ATP synthesis coupled electron transport
AM338_10615	COG0650	Formate hydrogenlyase subunit 4
AM338_10620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM338_10625	COG4237	Hydrogenase 4 membrane
AM338_10630	COG0651	ATP synthesis coupled electron transport
AM338_10635	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM338_10635	COG3261	NADH dehydrogenase
AM338_10640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM338_10645	COG3260	NADH ubiquinone oxidoreductase 20
AM338_10655	COG3604	Transcriptional regulator
AM338_10660	COG2116	formate transmembrane transporter activity
AM338_10670	COG0628	permease
AM338_10675	COG4783	chaperone-mediated protein folding
AM338_10680	COG1393	Belongs to the ArsC family
AM338_10690	COG2233	PERMEase
AM338_10710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM338_10715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM338_10720	COG0248	Ppx GppA phosphatase
AM338_10725	COG2200	EAL domain
AM338_10745	COG3133	Outer membrane lipoprotein
AM338_10760	COG0516	GMP reductase activity
AM338_10760	COG0517	IMP dehydrogenase activity
AM338_10770	COG1645	bacterial-type flagellum-dependent swarming motility
AM338_10785	COG2976	Protein conserved in bacteria
AM338_10815	COG4953	penicillin-binding protein 1C
AM338_10820	COG2373	Large extracellular alpha-helical protein
AM338_10825	COG2897	thiosulfate sulfurtransferase activity
AM338_10840	COG2975	iron-sulfur cluster assembly
AM338_10845	COG0633	Ferredoxin
AM338_10865	COG0822	iron-sulfur transferase activity
AM338_10885	COG0483	inositol monophosphate 1-phosphatase activity
AM338_10890	COG1073	alpha beta
AM338_10895	COG3711	transcriptional antiterminator
AM338_10900	COG2814	Major facilitator Superfamily
AM338_10905	COG0583	DNA-binding transcription factor activity
AM338_10910	COG4638	Rieske (2fe-2S)
AM338_10935	COG2259	Doxx family
AM338_10940	COG2017	converts alpha-aldose to the beta-anomer
AM338_10945	COG1063	alcohol dehydrogenase
AM338_10950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_10955	COG1129	ABC transporter
AM338_10960	COG1879	ABC-type sugar transport system periplasmic component
AM338_10965	COG0457	Tetratricopeptide repeat
AM338_10970	COG1940	carbohydrate kinase activity
AM338_10980	COG1017	nitric oxide dioxygenase activity
AM338_10980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_10985	COG0347	Belongs to the P(II) protein family
AM338_10990	COG2204	response regulator
AM338_10995	COG3170	Tfp pilus assembly protein FimV
AM338_11000	COG2205	protein histidine kinase activity
AM338_11005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM338_11005	COG0047	phosphoribosylformylglycinamidine synthase activity
AM338_11020	COG0590	tRNA wobble adenosine to inosine editing
AM338_11025	COG0560	Phosphoserine phosphatase
AM338_11030	COG1737	Transcriptional regulator
AM338_11035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_11060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM338_11085	COG0681	Belongs to the peptidase S26 family
AM338_11095	COG3086	response to oxidative stress
AM338_11100	COG3026	antisigma factor binding
AM338_11105	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM338_11110	COG1595	DNA-templated transcription, initiation
AM338_11115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM338_11120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM338_11125	COG0513	Belongs to the DEAD box helicase family
AM338_11130	COG0583	DNA-binding transcription factor activity
AM338_11150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM338_11160	COG3118	belongs to the thioredoxin family
AM338_11170	COG0045	succinate-CoA ligase (ADP-forming) activity
AM338_11170	COG1042	CoA-binding domain protein
AM338_11170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM338_11175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM338_11180	COG5544	Lipoprotein
AM338_11185	COG0477	Major facilitator Superfamily
AM338_11215	COG0542	response to heat
AM338_11225	COG0564	pseudouridine synthase activity
AM338_11230	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM338_11240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM338_11245	COG0077	Prephenate dehydratase
AM338_11245	COG1605	Chorismate mutase
AM338_11250	COG0287	Prephenate dehydrogenase
AM338_11250	COG1605	Chorismate mutase
AM338_11255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM338_11270	COG2199	diguanylate cyclase activity
AM338_11275	COG2885	chlorophyll binding
AM338_11300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM338_11305	COG4137	Cytochrome C assembly protein
AM338_11310	COG4536	flavin adenine dinucleotide binding
AM338_11330	COG0497	DNA recombination
AM338_11335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM338_11340	COG2914	Belongs to the UPF0125 (RnfH) family
AM338_11345	COG2867	negative regulation of translational initiation
AM338_11360	COG3468	outer membrane autotransporter barrel domain protein
AM338_11390	COG0366	Alpha amylase catalytic
AM338_11410	COG0579	oxidoreductase
AM338_11415	COG1012	belongs to the aldehyde dehydrogenase family
AM338_11420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM338_11425	COG1113	amino acid transport
AM338_11430	COG1802	Transcriptional regulator
AM338_11435	COG1652	LysM domain
AM338_11440	COG0401	homolog of Blt101
AM338_11445	COG0640	Transcriptional regulator
AM338_11450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM338_11455	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM338_11470	COG4575	ribosome binding
AM338_11475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM338_11480	COG1780	Probably involved in ribonucleotide reductase function
AM338_11485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM338_11490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM338_11500	COG4175	Glycine betaine
AM338_11505	COG4176	ABC-type proline glycine betaine transport system permease component
AM338_11510	COG2113	Glycine betaine
AM338_11515	COG2814	Major facilitator Superfamily
AM338_11520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM338_11530	COG1846	Transcriptional regulator
AM338_11535	COG1566	PFAM secretion protein HlyD family protein
AM338_11540	COG2814	Major facilitator Superfamily
AM338_11555	COG1238	metal cluster binding
AM338_11560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_11610	COG1546	Belongs to the CinA family
AM338_11615	COG2951	lytic endotransglycosylase activity
AM338_11620	COG3730	PTS system glucitol sorbitol-specific
AM338_11625	COG3732	PTS system glucitol sorbitol-specific
AM338_11630	COG3731	PTS system glucitol sorbitol-specific IIA component
AM338_11635	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_11640	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_11645	COG1349	DNA-binding transcription factor activity
AM338_11650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM338_11650	COG0517	IMP dehydrogenase activity
AM338_11670	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM338_11675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_11680	COG1609	Transcriptional regulator
AM338_11685	COG1263	PTS System
AM338_11685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_11690	COG2723	6-phospho-beta-galactosidase activity
AM338_11695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM338_11705	COG3260	NADH ubiquinone oxidoreductase 20
AM338_11710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM338_11715	COG3261	NADH dehydrogenase
AM338_11715	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM338_11720	COG0650	Formate hydrogenlyase subunit 4
AM338_11725	COG0651	ATP synthesis coupled electron transport
AM338_11730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_11745	COG0375	protein maturation
AM338_11750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM338_11755	COG0298	carbon dioxide binding
AM338_11760	COG0409	Hydrogenase expression formation protein
AM338_11765	COG0309	Hydrogenase expression formation protein (HypE)
AM338_11770	COG3604	Transcriptional regulator
AM338_11785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM338_11790	COG1349	DNA-binding transcription factor activity
AM338_11795	COG2084	Dehydrogenase
AM338_11800	COG3395	kinase activity
AM338_11805	COG0235	Class ii aldolase
AM338_11810	COG3622	Belongs to the hyi family
AM338_11815	COG2610	gluconate transmembrane transporter activity
AM338_11820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM338_11825	COG1388	LysM domain
AM338_11825	COG4942	peptidase
AM338_11880	COG2234	aminopeptidase activity
AM338_11885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM338_11890	COG1518	maintenance of DNA repeat elements
AM338_11905	COG1857	crispr-associated protein
AM338_11920	COG1203	CRISPR-associated helicase, Cas3
AM338_11945	COG0720	synthase
AM338_11950	COG0644	oxidoreductase
AM338_11955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM338_11960	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AM338_11965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM338_11970	COG2086	electron transfer activity
AM338_11975	COG0477	Major facilitator Superfamily
AM338_11980	COG0277	FAD linked oxidase domain protein
AM338_11985	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_11990	COG2223	nitrite transmembrane transporter activity
AM338_11995	COG1070	Carbohydrate kinase
AM338_12000	COG0602	queuosine metabolic process
AM338_12010	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM338_12025	COG3956	TIGRFAM MazG family protein
AM338_12030	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM338_12035	COG2336	PFAM SpoVT AbrB
AM338_12040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM338_12045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM338_12050	COG3437	response regulator, receiver
AM338_12050	COG3850	Histidine kinase
AM338_12050	COG4999	Histidine kinase
AM338_12050	COG2205	protein histidine kinase activity
AM338_12055	COG4948	Mandelate Racemase Muconate Lactonizing
AM338_12060	COG4948	Mandelate Racemase Muconate Lactonizing
AM338_12065	COG2271	Major facilitator Superfamily
AM338_12070	COG0716	FMN binding
AM338_12075	COG0564	pseudouridine synthase activity
AM338_12080	COG3098	single-species biofilm formation
AM338_12095	COG1611	Belongs to the LOG family
AM338_12100	COG0814	amino acid
AM338_12105	COG1760	l-serine dehydratase
AM338_12115	COG1454	alcohol dehydrogenase
AM338_12120	COG0235	Class ii aldolase
AM338_12125	COG0738	Major facilitator superfamily
AM338_12135	COG1070	Carbohydrate kinase
AM338_12145	COG1349	DNA-binding transcription factor activity
AM338_12155	COG2363	Small membrane protein
AM338_12160	COG0583	DNA-binding transcription factor activity
AM338_12170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM338_12175	COG2166	iron-sulfur cluster assembly
AM338_12180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM338_12185	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM338_12210	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM338_12215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM338_12215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM338_12220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM338_12225	COG1074	ATP-dependent DNA helicase activity
AM338_12230	COG1025	Belongs to the peptidase M16 family
AM338_12235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM338_12240	COG4967	type IV pilus modification protein PilV
AM338_12250	COG4795	General secretion pathway protein
AM338_12255	COG2165	general secretion pathway protein
AM338_12270	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AM338_12285	COG0861	Integral membrane protein TerC family
AM338_12295	COG0667	Aldo Keto reductase
AM338_12310	COG1609	Transcriptional regulator
AM338_12315	COG0019	diaminopimelate decarboxylase activity
AM338_12320	COG0583	DNA-binding transcription factor activity
AM338_12325	COG1794	racemase activity, acting on amino acids and derivatives
AM338_12330	COG2814	Major facilitator Superfamily
AM338_12335	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_12345	COG0183	Belongs to the thiolase family
AM338_12350	COG0814	amino acid
AM338_12355	COG2771	luxR family
AM338_12360	COG3710	Transcriptional regulator
AM338_12390	COG0457	Tetratricopeptide repeat
AM338_12400	COG3710	Transcriptional regulator
AM338_12400	COG0457	Tetratricopeptide repeat
AM338_12420	COG2197	response regulator
AM338_12425	COG2197	response regulator
AM338_12525	COG3385	transposase activity
AM338_12530	COG3387	PFAM Glycoside hydrolase 15-related
AM338_12560	COG4974	Belongs to the 'phage' integrase family
AM338_12570	COG4942	peptidase
AM338_12580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM338_12585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM338_12590	COG2080	2 iron, 2 sulfur cluster binding
AM338_12600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM338_12605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM338_12610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM338_12620	COG0549	Belongs to the carbamate kinase family
AM338_12625	COG3608	succinylglutamate desuccinylase aspartoacylase
AM338_12625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM338_12630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM338_12635	COG2068	MobA-Related Protein
AM338_12640	COG0493	'glutamate synthase
AM338_12640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_12645	COG0402	S-adenosylhomocysteine deaminase activity
AM338_12650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM338_12655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM338_12655	COG2080	2 iron, 2 sulfur cluster binding
AM338_12660	COG2233	PERMEase
AM338_12665	COG0402	S-adenosylhomocysteine deaminase activity
AM338_12670	COG2252	PERMEase
AM338_12675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_12690	COG2233	PERMEase
AM338_12705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM338_12715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM338_12720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM338_12725	COG4974	Belongs to the 'phage' integrase family
AM338_12730	COG0716	FMN binding
AM338_12740	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM338_12750	COG1272	protein, Hemolysin III
AM338_12760	COG2723	6-phospho-beta-galactosidase activity
AM338_12765	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_12785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM338_12790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM338_12795	COG0006	proline dipeptidase activity
AM338_12820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM338_12835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM338_12860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM338_12860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM338_12865	COG1703	isobutyryl-CoA mutase activity
AM338_12870	COG1024	Enoyl-CoA hydratase
AM338_12875	COG0427	acetyl-CoA hydrolase
AM338_12880	COG0583	DNA-binding transcription factor activity
AM338_12890	COG1279	arginine transmembrane transporter activity
AM338_12895	COG0668	transmembrane transport
AM338_12900	COG0191	fructose-bisphosphate aldolase activity
AM338_12920	COG1072	(Pantothenic acid kinase))
AM338_12925	COG3722	fumarate hydratase activity
AM338_12930	COG1494	fructose-1,6-bisphosphatase
AM338_12935	COG1063	alcohol dehydrogenase
AM338_12940	COG2213	PTS system mannitol-specific
AM338_12945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_12950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM338_12955	COG0501	Belongs to the peptidase M48B family
AM338_12965	COG1166	arginine decarboxylase activity
AM338_12990	COG2814	Major facilitator Superfamily
AM338_13000	COG2356	endonuclease I
AM338_13005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM338_13010	COG0189	ligase activity
AM338_13025	COG2805	Type II/IV secretion system protein
AM338_13030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM338_13035	COG0762	integral membrane protein
AM338_13045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM338_13050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM338_13060	COG0252	asparaginase activity
AM338_13070	COG3171	Protein conserved in bacteria
AM338_13085	COG1194	a g-specific adenine glycosylase
AM338_13100	COG2211	Major facilitator Superfamily
AM338_13105	COG1982	Orn Lys Arg decarboxylase major
AM338_13115	COG1811	Na channel or pump
AM338_13150	COG3436	PFAM IS66 Orf2 family protein
AM338_13155	COG4372	Transposase
AM338_13170	COG1846	Transcriptional regulator
AM338_13185	COG0531	amino acid
AM338_13190	COG1982	Orn Lys Arg decarboxylase major
AM338_13195	COG0531	amino acid
AM338_13210	COG0604	alcohol dehydrogenase
AM338_13275	COG2831	hemolysin activation secretion protein
AM338_13300	COG4869	propanediol catabolic process
AM338_13305	COG4820	ethanolamine utilization protein (EutJ)
AM338_13330	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM338_13340	COG1012	belongs to the aldehyde dehydrogenase family
AM338_13350	COG0693	protein deglycase activity
AM338_13360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM338_13380	COG3344	reverse transcriptase
AM338_13385	COG2972	Histidine kinase
AM338_13390	COG2207	Transcriptional regulator
AM338_13400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM338_13415	COG1309	transcriptional regulator
AM338_13460	COG3596	GTP binding
AM338_13465	COG2378	regulation of single-species biofilm formation
AM338_13490	COG2003	Belongs to the UPF0758 family
AM338_13525	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM338_13540	COG4795	General secretion pathway protein
AM338_13555	COG2165	general secretion pathway protein
AM338_13560	COG1459	type II secretion system
AM338_13575	COG3031	protein transport across the cell outer membrane
AM338_13585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM338_13590	COG3064	Membrane
AM338_13600	COG1620	l-lactate permease
AM338_13605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM338_13610	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AM338_13615	COG0247	lactate metabolic process
AM338_13620	COG0277	FAD linked oxidase domain protein
AM338_13625	COG0277	FAD linked oxidase domain protein
AM338_13630	COG2186	Transcriptional regulator
AM338_13635	COG0456	acetyltransferase
AM338_13640	COG0318	PFAM AMP-dependent synthetase and ligase
AM338_13650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM338_13655	COG0156	8-amino-7-oxononanoate synthase activity
AM338_13665	COG0795	lipopolysaccharide-transporting ATPase activity
AM338_13670	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM338_13680	COG2244	polysaccharide biosynthetic process
AM338_13685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM338_13690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM338_13695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM338_13700	COG0306	phosphate transporter
AM338_13705	COG0754	glutathionylspermidine amidase activity
AM338_13710	COG0625	glutathione transferase activity
AM338_13715	COG0298	carbon dioxide binding
AM338_13720	COG0375	protein maturation
AM338_13725	COG1773	rubredoxin
AM338_13730	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM338_13735	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM338_13740	COG5557	Pfam Polysulphide reductase, NrfD
AM338_13745	COG0437	4 iron, 4 sulfur cluster binding
AM338_13750	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM338_13775	COG0667	Aldo Keto reductase
AM338_13785	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_13790	COG0848	biopolymer transport protein
AM338_13795	COG0811	peptide transport
AM338_13805	COG0626	cystathionine gamma-synthase activity
AM338_13810	COG0586	Pfam SNARE associated Golgi protein
AM338_13815	COG2207	Transcriptional regulator
AM338_13820	COG1979	alcohol dehydrogenase
AM338_13825	COG0656	L-ascorbic acid biosynthetic process
AM338_13835	COG4238	major outer membrane lipoprotein
AM338_13840	COG1032	radical SAM domain protein
AM338_13845	COG2132	Multicopper oxidase
AM338_13850	COG0204	Acyl-transferase
AM338_13855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM338_13860	COG4166	transmembrane transport
AM338_13865	COG2944	sequence-specific DNA binding
AM338_13875	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM338_13880	COG3111	PFAM Bacterial OB fold (BOF) protein
AM338_13885	COG0745	RESPONSE REGULATOR receiver
AM338_13890	COG0642	Histidine kinase
AM338_13905	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM338_13910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM338_13915	COG0187	DNA topoisomerase II activity
AM338_13920	COG3150	esterase
AM338_13925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM338_13930	COG3151	Protein conserved in bacteria
AM338_13935	COG0494	nUDIX hydrolase
AM338_13940	COG1538	Outer membrane efflux protein
AM338_13955	COG0754	glutathionylspermidine amidase activity
AM338_13960	COG3384	dioxygenase
AM338_13980	COG2960	long-chain fatty acid transporting porin activity
AM338_13985	COG3539	Fimbrial protein
AM338_13990	COG3188	usher protein
AM338_13995	COG3121	Chaperone
AM338_14000	COG3539	Fimbrial protein
AM338_14010	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM338_14015	COG2268	Band 7 protein
AM338_14035	COG3025	triphosphatase activity
AM338_14045	COG4991	sh3 domain protein
AM338_14055	COG1968	undecaprenyl-diphosphatase activity
AM338_14060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM338_14070	COG0583	DNA-binding transcription factor activity
AM338_14090	COG0471	metal ion transport
AM338_14110	COG0358	DNA primase activity
AM338_14120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM338_14135	COG2375	cellular response to nickel ion
AM338_14145	COG1695	Transcriptional regulator
AM338_14150	COG0840	transmembrane signaling receptor activity
AM338_14165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM338_14175	COG1609	Transcriptional regulator
AM338_14180	COG3250	beta-galactosidase activity
AM338_14185	COG2731	YhcH YjgK YiaL family protein
AM338_14190	COG0531	amino acid
AM338_14200	COG3408	Glycogen debranching enzyme
AM338_14200	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM338_14205	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM338_14205	COG1902	pentaerythritol trinitrate reductase activity
AM338_14210	COG5499	transcription regulator containing HTH domain
AM338_14215	COG4680	protein conserved in bacteria
AM338_14230	COG1451	nucleotide metabolic process
AM338_14235	COG2949	membrane
AM338_14240	COG0673	inositol 2-dehydrogenase activity
AM338_14245	COG0861	Integral membrane protein TerC family
AM338_14250	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM338_14260	COG2721	sulfolactate sulfo-lyase activity
AM338_14270	COG2271	Major facilitator Superfamily
AM338_14275	COG2186	Transcriptional regulator
AM338_14280	COG0586	Pfam SNARE associated Golgi protein
AM338_14290	COG1422	Protein of unknown function (DUF1090)
AM338_14295	COG4575	ribosome binding
AM338_14300	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM338_14310	COG2259	Doxx family
AM338_14315	COG0435	Glutathione S-transferase
AM338_14320	COG3152	Membrane
AM338_14340	COG3152	Membrane
AM338_14350	COG0583	DNA-binding transcription factor activity
AM338_14355	COG1741	Belongs to the pirin family
AM338_14370	COG0814	amino acid
AM338_14375	COG1760	l-serine dehydratase
AM338_14380	COG0251	oxidation-reduction process
AM338_14385	COG1882	Formate acetyltransferase
AM338_14390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM338_14400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM338_14405	COG0583	DNA-binding transcription factor activity
AM338_14430	COG1929	Belongs to the glycerate kinase type-1 family
AM338_14435	COG2084	Dehydrogenase
AM338_14445	COG2271	Major facilitator Superfamily
AM338_14450	COG2721	sulfolactate sulfo-lyase activity
AM338_14455	COG2002	toxin-antitoxin pair type II binding
AM338_14465	COG1349	DNA-binding transcription factor activity
AM338_14480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_14490	COG3716	PTS system mannose fructose sorbose family IID component
AM338_14495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_14500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM338_14505	COG2222	sugar isomerase
AM338_14515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_14530	COG3715	PTS system
AM338_14535	COG3716	PTS system mannose fructose sorbose family IID component
AM338_14540	COG0363	glucosamine-6-phosphate deaminase activity
AM338_14545	COG3539	Fimbrial protein
AM338_14550	COG3121	Chaperone
AM338_14555	COG3188	usher protein
AM338_14560	COG3539	Fimbrial protein
AM338_14565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM338_14570	COG3107	peptidoglycan biosynthetic process
AM338_14580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM338_14585	COG2823	Periplasmic or secreted lipoprotein
AM338_14590	COG0701	Predicted permease
AM338_14595	COG0702	epimerase
AM338_14600	COG0693	protein deglycase activity
AM338_14615	COG3153	acetyltransferase
AM338_14635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM338_14640	COG0814	amino acid
AM338_14645	COG0513	Belongs to the DEAD box helicase family
AM338_14655	COG4785	May be involved in cell division
AM338_14670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM338_14685	COG0195	Participates in both transcription termination and antitermination
AM338_14705	COG2194	sulfuric ester hydrolase activity
AM338_14720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM338_14730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM338_14735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM338_14745	COG1534	Rna-binding protein
AM338_14750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM338_14755	COG2027	D-alanyl-D-alanine carboxypeptidase
AM338_14765	COG0697	spore germination
AM338_14780	COG0142	geranyltranstransferase activity
AM338_14785	COG3423	Transcriptional regulator
AM338_14795	COG5007	Belongs to the BolA IbaG family
AM338_14800	COG3113	response to antibiotic
AM338_14805	COG2854	intermembrane phospholipid transfer
AM338_14810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM338_14815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM338_14820	COG1127	ABC transporter
AM338_14825	COG0530	calcium, potassium:sodium antiporter activity
AM338_14830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM338_14830	COG0517	IMP dehydrogenase activity
AM338_14835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM338_14840	COG3117	lipopolysaccharide transmembrane transporter activity
AM338_14845	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM338_14850	COG1137	ATPase activity
AM338_14855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM338_14860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM338_14865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_14875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_14880	COG0515	serine threonine protein kinase
AM338_14890	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM338_14895	COG5002	protein histidine kinase activity
AM338_14895	COG2198	Histidine kinase
AM338_14895	COG0784	Response regulator, receiver
AM338_14900	COG1242	4 iron, 4 sulfur cluster binding
AM338_14915	COG0069	glutamate synthase activity
AM338_14915	COG0067	glutamate synthase
AM338_14915	COG0070	glutamate synthase
AM338_14920	COG0493	'glutamate synthase
AM338_14930	COG3539	Fimbrial protein
AM338_14935	COG3121	Chaperone
AM338_14940	COG3188	usher protein
AM338_14950	COG3539	Fimbrial protein
AM338_14965	COG3344	reverse transcriptase
AM338_14980	COG4804	nuclease activity
AM338_14985	COG2731	YhcH YjgK YiaL family protein
AM338_15020	COG3069	C4-dicarboxylate transmembrane transporter activity
AM338_15025	COG2969	positive regulation of protein catabolic process
AM338_15030	COG0625	glutathione transferase activity
AM338_15050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM338_15055	COG3105	Protein conserved in bacteria
AM338_15060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM338_15065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM338_15085	COG2732	(Barnase) inhibitor
AM338_15105	COG0583	DNA-binding transcription factor activity
AM338_15110	COG0312	modulator of DNA gyrase
AM338_15115	COG3164	Protein of unknown function
AM338_15120	COG1530	ribonuclease E activity
AM338_15125	COG0424	maF-like protein
AM338_15130	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM338_15135	COG1792	Involved in formation and maintenance of cell shape
AM338_15140	COG1077	Cell shape determining protein MreB Mrl
AM338_15155	COG2199	diguanylate cyclase activity
AM338_15155	COG2200	EAL domain
AM338_15160	COG0604	alcohol dehydrogenase
AM338_15170	COG0511	ligase activity, forming carbon-carbon bonds
AM338_15175	COG0439	Biotin carboxylase
AM338_15180	COG3924	membrane
AM338_15185	COG4145	pantothenate transmembrane transporter activity
AM338_15195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM338_15205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM338_15225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM338_15245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM338_15250	COG4597	amino acid ABC transporter
AM338_15255	COG0765	amino acid transport
AM338_15260	COG1126	abc transporter atp-binding protein
AM338_15300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM338_15320	COG0551	DNA topoisomerase type I activity
AM338_15330	COG0758	DNA mediated transformation
AM338_15350	COG0569	domain protein
AM338_15360	COG3036	rescue of stalled ribosome
AM338_15365	COG0789	Transcriptional regulator
AM338_15395	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM338_15405	COG0201	protein transport
AM338_15495	COG0089	rRNA binding
AM338_15525	COG3409	Peptidoglycan-binding domain 1 protein
AM338_15525	COG3267	Type II secretory pathway component ExeA
AM338_15530	COG3031	protein transport across the cell outer membrane
AM338_15535	COG1450	Type ii and iii secretion system protein
AM338_15540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM338_15545	COG1459	type II secretion system
AM338_15550	COG2165	general secretion pathway protein
AM338_15555	COG2165	general secretion pathway protein
AM338_15560	COG2165	general secretion pathway protein
AM338_15565	COG4795	General secretion pathway protein
AM338_15575	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM338_15580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AM338_15585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM338_15590	COG2193	ferroxidase activity
AM338_15595	COG2906	2 iron, 2 sulfur cluster binding
AM338_15600	COG3979	chitinase
AM338_15645	COG2964	Protein conserved in bacteria
AM338_15650	COG0545	Peptidyl-prolyl cis-trans isomerase
AM338_15660	COG1047	Peptidyl-prolyl cis-trans
AM338_15665	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM338_15685	COG0488	(ABC) transporter
AM338_15690	COG0429	hydrolase of the alpha beta-hydrolase fold
AM338_15700	COG3954	Phosphoribulokinase
AM338_15705	COG1765	OsmC-like protein
AM338_15715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM338_15720	COG1289	transmembrane transporter activity
AM338_15725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM338_15730	COG0512	Glutamine amidotransferase of anthranilate synthase
AM338_15735	COG2184	nucleotidyltransferase activity
AM338_15745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM338_15755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM338_15760	COG2146	nitrite reductase [NAD(P)H] activity
AM338_15765	COG2116	formate transmembrane transporter activity
AM338_15780	COG0531	amino acid
AM338_15785	COG2222	sugar isomerase
AM338_15795	COG1082	Xylose isomerase domain protein TIM barrel
AM338_15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_15805	COG2188	Transcriptional regulator
AM338_15810	COG0626	cystathionine gamma-synthase activity
AM338_15825	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM338_15830	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM338_15835	COG3457	Alanine racemase
AM338_15845	COG2188	Transcriptional regulator
AM338_15855	COG0180	Tryptophanyl-tRNA synthetase
AM338_15860	COG0546	phosphoglycolate phosphatase activity
AM338_15865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM338_15870	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM338_15875	COG3266	domain, Protein
AM338_15890	COG4796	Type ii and iii secretion system protein
AM338_15905	COG3166	PFAM Fimbrial assembly family protein
AM338_15910	COG4972	Pilus assembly protein
AM338_15915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM338_15920	COG0494	nUDIX hydrolase
AM338_15930	COG1011	Hydrolase
AM338_15935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM338_15945	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM338_15960	COG2205	protein histidine kinase activity
AM338_15965	COG0745	RESPONSE REGULATOR receiver
AM338_15975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM338_15980	COG2183	response to ionizing radiation
AM338_15990	COG1918	ferrous iron import across plasma membrane
AM338_15995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM338_16010	COG5464	transposase or invertase
AM338_16020	COG1040	competence protein
AM338_16030	COG2610	gluconate transmembrane transporter activity
AM338_16035	COG1640	4-alpha-glucanotransferase
AM338_16040	COG0058	SHG alpha-glucan phosphorylase activity
AM338_16055	COG1690	Belongs to the RtcB family
AM338_16060	COG4650	regulator
AM338_16065	COG1349	DNA-binding transcription factor activity
AM338_16080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM338_16090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM338_16095	COG0058	SHG alpha-glucan phosphorylase activity
AM338_16120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM338_16125	COG2095	MarC family integral membrane protein
AM338_16130	COG2610	gluconate transmembrane transporter activity
AM338_16135	COG3265	gluconokinase activity
AM338_16140	COG1609	Transcriptional regulator
AM338_16145	COG1741	Belongs to the pirin family
AM338_16150	COG0673	inositol 2-dehydrogenase activity
AM338_16160	COG1247	-acetyltransferase
AM338_16165	COG3157	Type VI secretion system effector, Hcp
AM338_16185	COG0405	Gamma-glutamyltransferase
AM338_16195	COG0584	glycerophosphoryl diester phosphodiesterase
AM338_16200	COG3842	ATPase activity
AM338_16205	COG0395	ABC-type sugar transport system, permease component
AM338_16210	COG1175	transmembrane transport
AM338_16215	COG1653	transport
AM338_16220	COG0410	ABC transporter
AM338_16225	COG0411	ABC transporter
AM338_16230	COG4177	L-phenylalanine transmembrane transporter activity
AM338_16235	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM338_16240	COG0683	leucine binding
AM338_16250	COG0456	acetyltransferase
AM338_16255	COG0683	leucine binding
AM338_16260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM338_16265	COG2177	Part of the ABC transporter FtsEX involved in
AM338_16270	COG2884	Cell division ATP-binding protein ftsE
AM338_16275	COG0552	protein localization to endoplasmic reticulum
AM338_16280	COG0742	ribosomal rna small subunit methyltransferase
AM338_16285	COG3776	membrane
AM338_16295	COG3714	YhhN family
AM338_16300	COG2217	Heavy metal translocating P-type atpase
AM338_16310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM338_16320	COG0477	Major facilitator Superfamily
AM338_16325	COG0628	permease
AM338_16330	COG2091	lysine biosynthetic process via aminoadipic acid
AM338_16335	COG0747	negative chemotaxis
AM338_16340	COG0601	transmembrane transport
AM338_16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM338_16350	COG0444	Belongs to the ABC transporter superfamily
AM338_16355	COG1124	(ABC) transporter
AM338_16365	COG3209	COG3209 Rhs family protein
AM338_16380	COG5433	transposase activity
AM338_16385	COG0842	Transport permease protein
AM338_16390	COG1129	ABC transporter
AM338_16390	COG0842	Transport permease protein
AM338_16395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_16420	COG2081	HI0933 family
AM338_16425	COG0306	phosphate transporter
AM338_16435	COG0589	response to stress
AM338_16445	COG3104	oligopeptide transport
AM338_16450	COG0742	ribosomal rna small subunit methyltransferase
AM338_16455	COG0339	signal peptide processing
AM338_16460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM338_16465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM338_16480	COG0640	Transcriptional regulator
AM338_16485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM338_16490	COG1393	Belongs to the ArsC family
AM338_16500	COG3065	identical protein binding
AM338_16510	COG2197	response regulator
AM338_16515	COG1285	pathogenesis
AM338_16530	COG3247	response to pH
AM338_16535	COG2771	luxR family
AM338_16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_16550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM338_16560	COG2207	Transcriptional regulator
AM338_16565	COG2207	Transcriptional regulator
AM338_16570	COG0076	glutamate decarboxylase activity
AM338_16575	COG1858	cytochrome C peroxidase
AM338_16580	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM338_16585	COG2197	response regulator
AM338_16590	COG0583	DNA-binding transcription factor activity
AM338_16595	COG1295	ribonuclease BN
AM338_16600	COG0477	Major facilitator Superfamily
AM338_16605	COG2982	Protein involved in outer membrane biogenesis
AM338_16610	COG2200	EAL domain
AM338_16620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_16625	COG0612	Peptidase, M16
AM338_16645	COG2199	diguanylate cyclase activity
AM338_16645	COG2200	EAL domain
AM338_16650	COG0457	Tetratricopeptide repeat
AM338_16650	COG3118	belongs to the thioredoxin family
AM338_16655	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM338_16660	COG1215	transferase activity, transferring glycosyl groups
AM338_16665	COG1215	transferase activity, transferring glycosyl groups
AM338_16690	COG2194	sulfuric ester hydrolase activity
AM338_16710	COG0814	amino acid
AM338_16715	COG4608	Belongs to the ABC transporter superfamily
AM338_16720	COG0444	Belongs to the ABC transporter superfamily
AM338_16725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM338_16730	COG0601	transmembrane transport
AM338_16740	COG0747	negative chemotaxis
AM338_16760	COG2194	sulfuric ester hydrolase activity
AM338_16765	COG2223	nitrite transmembrane transporter activity
AM338_16775	COG5571	outer membrane autotransporter
AM338_16780	COG2818	Glycosylase
AM338_16785	COG0456	acetyltransferase
AM338_16790	COG0243	molybdopterin cofactor binding
AM338_16795	COG2885	chlorophyll binding
AM338_16810	COG2944	sequence-specific DNA binding
AM338_16815	COG1278	Cold shock
AM338_16845	COG3274	enterobacterial common antigen metabolic process
AM338_16850	COG4682	membrane
AM338_16855	COG4682	membrane
AM338_16860	COG1070	Carbohydrate kinase
AM338_16870	COG4213	ABC transporter substrate-binding protein
AM338_16875	COG1129	ABC transporter
AM338_16880	COG4214	carbohydrate transport
AM338_16885	COG2207	Transcriptional regulator
AM338_16885	COG1609	Transcriptional regulator
AM338_16890	COG2992	FlgJ-related protein
AM338_16895	COG0366	Alpha amylase catalytic
AM338_16900	COG3977	Valine--pyruvate aminotransferase
AM338_16905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM338_16910	COG1414	Transcriptional regulator
AM338_16920	COG2731	YhcH YjgK YiaL family protein
AM338_16925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AM338_16930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM338_16935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM338_16940	COG1070	Carbohydrate kinase
AM338_16945	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM338_16950	COG3623	hexulose-6-phosphate isomerase
AM338_16955	COG0235	Class ii aldolase
AM338_16965	COG3713	MltA-interacting MipA family protein
AM338_16970	COG0583	DNA-binding transcription factor activity
AM338_16975	COG1566	PFAM secretion protein HlyD family protein
AM338_16990	COG1012	belongs to the aldehyde dehydrogenase family
AM338_16995	COG1454	alcohol dehydrogenase
AM338_17000	COG3276	selenocysteine insertion sequence binding
AM338_17010	COG0625	glutathione transferase activity
AM338_17015	COG3209	COG3209 Rhs family protein
AM338_17045	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM338_17065	COG1566	PFAM secretion protein HlyD family protein
AM338_17075	COG2213	PTS system mannitol-specific
AM338_17075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_17085	COG3722	fumarate hydratase activity
AM338_17105	COG1620	l-lactate permease
AM338_17110	COG2186	Transcriptional regulator
AM338_17120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM338_17125	COG1045	serine acetyltransferase
AM338_17140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM338_17145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM338_17160	COG4942	peptidase
AM338_17165	COG2861	carbohydrate metabolic process
AM338_17170	COG1216	Glycosyl transferase, family 2
AM338_17180	COG0156	8-amino-7-oxononanoate synthase activity
AM338_17190	COG0859	PFAM glycosyl transferase family 9
AM338_17195	COG0859	PFAM glycosyl transferase family 9
AM338_17215	COG3642	lipopolysaccharide core region biosynthetic process
AM338_17220	COG1442	glycosyl transferase family 8
AM338_17225	COG1442	glycosyl transferase family 8
AM338_17230	COG0438	transferase activity, transferring glycosyl groups
AM338_17235	COG1442	glycosyl transferase family 8
AM338_17240	COG0515	serine threonine protein kinase
AM338_17245	COG0438	transferase activity, transferring glycosyl groups
AM338_17250	COG0859	PFAM glycosyl transferase family 9
AM338_17255	COG1519	Transferase
AM338_17285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM338_17315	COG1561	YicC-like family, N-terminal region
AM338_17325	COG3645	SOS response
AM338_17330	COG2860	membrane
AM338_17350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM338_17355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM338_17360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM338_17365	COG0786	glutamate:sodium symporter activity
AM338_17370	COG2233	PERMEase
AM338_17375	COG2982	Protein involved in outer membrane biogenesis
AM338_17380	COG1501	Belongs to the glycosyl hydrolase 31 family
AM338_17385	COG2211	Major facilitator Superfamily
AM338_17400	COG2814	Major facilitator Superfamily
AM338_17405	COG0697	spore germination
AM338_17410	COG1464	Belongs to the NlpA lipoprotein family
AM338_17440	COG2252	PERMEase
AM338_17450	COG2271	Major facilitator Superfamily
AM338_17455	COG2271	Major facilitator Superfamily
AM338_17460	COG3851	Histidine kinase
AM338_17465	COG2197	response regulator
AM338_17470	COG0440	acetolactate synthase activity
AM338_17475	COG0028	Belongs to the TPP enzyme family
AM338_17520	COG2814	Major facilitator Superfamily
AM338_17525	COG0641	radical SAM
AM338_17535	COG2149	membrane
AM338_17545	COG3119	arylsulfatase activity
AM338_17550	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM338_17555	COG2207	Transcriptional regulator
AM338_17570	COG2188	Transcriptional regulator
AM338_17590	COG5645	(Lipo)protein
AM338_17595	COG0823	Involved in the tonB-independent uptake of proteins
AM338_17600	COG0644	oxidoreductase
AM338_17605	COG2271	Major facilitator Superfamily
AM338_17615	COG0800	Aldolase
AM338_17620	COG3734	2-keto-3-deoxy-galactonokinase
AM338_17625	COG2186	Transcriptional regulator
AM338_17635	COG0561	phosphatase activity
AM338_17640	COG3753	Protein conserved in bacteria
AM338_17645	COG0187	DNA topoisomerase II activity
AM338_17655	COG0592	DNA-directed DNA polymerase activity
AM338_17705	COG0814	amino acid
AM338_17720	COG2091	lysine biosynthetic process via aminoadipic acid
AM338_17725	COG0431	NADPH-dependent FMN reductase
AM338_17730	COG2252	PERMEase
AM338_17735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM338_17755	COG3436	PFAM IS66 Orf2 family protein
AM338_17765	COG3196	Protein conserved in bacteria
AM338_17770	COG0363	glucosamine-6-phosphate deaminase activity
AM338_17785	COG2723	6-phospho-beta-galactosidase activity
AM338_17790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_17790	COG1263	PTS System
AM338_17790	COG2190	(PTS) system
AM338_17795	COG3711	transcriptional antiterminator
AM338_17800	COG0704	Plays a role in the regulation of phosphate uptake
AM338_17805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM338_17810	COG0581	inorganic phosphate transmembrane transporter activity
AM338_17815	COG0573	inorganic phosphate transmembrane transporter activity
AM338_17820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM338_17825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM338_17875	COG3312	ion transport
AM338_17890	COG0716	FMN binding
AM338_17895	COG1522	sequence-specific DNA binding
AM338_17905	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM338_17920	COG1869	D-ribose catabolic process
AM338_17930	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_17935	COG1879	ABC-type sugar transport system periplasmic component
AM338_17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_17945	COG1609	Transcriptional regulator
AM338_17950	COG0477	Major facilitator Superfamily
AM338_17955	COG2186	Transcriptional regulator
AM338_17995	COG3085	chromosome segregation
AM338_18000	COG0606	chelatase, subunit chli
AM338_18020	COG3978	acetolactate synthase activity
AM338_18025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM338_18035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM338_18040	COG0583	DNA-binding transcription factor activity
AM338_18050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM338_18060	COG0210	DNA helicase
AM338_18065	COG0248	Ppx GppA phosphatase
AM338_18080	COG3118	belongs to the thioredoxin family
AM338_18090	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM338_18100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM338_18105	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM338_18110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM338_18115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM338_18120	COG1088	dTDP-glucose 4,6-dehydratase activity
AM338_18125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM338_18130	COG0456	acetyltransferase
AM338_18135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM338_18140	COG2244	polysaccharide biosynthetic process
AM338_18160	COG1113	amino acid transport
AM338_18185	COG0641	radical SAM
AM338_18190	COG3119	arylsulfatase activity
AM338_18195	COG3071	HemY protein
AM338_18200	COG2959	enzyme of heme biosynthesis
AM338_18205	COG1587	Uroporphyrinogen-III synthase
AM338_18220	COG3072	Adenylate cyclase
AM338_18235	COG5567	small periplasmic lipoprotein
AM338_18245	COG3159	Protein conserved in bacteria
AM338_18255	COG1011	Hydrolase
AM338_18260	COG0210	DNA helicase
AM338_18265	COG3698	Phosphodiester glycosidase
AM338_18270	COG0598	Magnesium transport protein CorA
AM338_18285	COG2962	Rard protein
AM338_18290	COG2050	protein possibly involved in aromatic compounds catabolism
AM338_18295	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AM338_18300	COG0514	ATP-dependent DNA helicase (RecQ)
AM338_18305	COG1280	lysine exporter protein (LysE YggA)
AM338_18310	COG1280	lysine exporter protein (LysE YggA)
AM338_18315	COG2267	carboxylic ester hydrolase activity
AM338_18320	COG0561	phosphatase activity
AM338_18330	COG0583	DNA-binding transcription factor activity
AM338_18340	COG0412	Dienelactone hydrolase
AM338_18345	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AM338_18355	COG1322	Protein conserved in bacteria
AM338_18365	COG3165	ubiquinone biosynthetic process from chorismate
AM338_18375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM338_18380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM338_18385	COG0805	protein transport
AM338_18390	COG0084	hydrolase, TatD family'
AM338_18395	COG0250	Participates in transcription elongation, termination and antitermination
AM338_18400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM338_18405	COG0543	2 iron, 2 sulfur cluster binding
AM338_18410	COG0183	Belongs to the thiolase family
AM338_18425	COG1739	Uncharacterized protein family UPF0029
AM338_18430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM338_18435	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM338_18465	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM338_18470	COG0746	molybdenum cofactor guanylyltransferase activity
AM338_18475	COG3084	Protein conserved in bacteria
AM338_18480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM338_18485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM338_18490	COG5339	Protein conserved in bacteria
AM338_18495	COG0204	Acyl-transferase
AM338_18505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM338_18505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM338_18525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM338_18535	COG2204	response regulator
AM338_18540	COG3852	Histidine kinase
AM338_18545	COG0174	glutamine synthetase
AM338_18560	COG2188	Transcriptional regulator
AM338_18565	COG1082	Xylose isomerase domain protein TIM barrel
AM338_18570	COG2271	Major facilitator Superfamily
AM338_18575	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM338_18580	COG2211	Major facilitator Superfamily
AM338_18585	COG2211	Major facilitator Superfamily
AM338_18590	COG1501	Belongs to the glycosyl hydrolase 31 family
AM338_18595	COG2017	converts alpha-aldose to the beta-anomer
AM338_18600	COG2942	2-epimerase
AM338_18605	COG3684	Belongs to the aldolase LacD family
AM338_18610	COG2084	Dehydrogenase
AM338_18615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_18620	COG1349	DNA-binding transcription factor activity
AM338_18625	COG1011	Hydrolase
AM338_18640	COG0456	acetyltransferase
AM338_18645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM338_18650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM338_18660	COG2864	formate dehydrogenase
AM338_18665	COG0437	4 iron, 4 sulfur cluster binding
AM338_18690	COG3711	transcriptional antiterminator
AM338_18690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_18695	COG1363	Peptidase, m42
AM338_18700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_18700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_18705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_18745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM338_18760	COG2258	MOSC domain
AM338_18765	COG2205	protein histidine kinase activity
AM338_18770	COG0745	RESPONSE REGULATOR receiver
AM338_18775	COG3678	ATP-independent chaperone mediated protein folding
AM338_18790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM338_18815	COG3152	Membrane
AM338_18820	COG3691	Protein conserved in bacteria
AM338_18825	COG0589	response to stress
AM338_18830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM338_18835	COG1494	fructose-1,6-bisphosphatase
AM338_18845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM338_18860	COG1575	Belongs to the MenA family. Type 1 subfamily
AM338_18865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM338_18875	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM338_18880	COG1609	Transcriptional regulator
AM338_18885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM338_18895	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AM338_18905	COG0626	cystathionine gamma-synthase activity
AM338_18910	COG0460	homoserine dehydrogenase
AM338_18910	COG0527	aspartate kinase activity
AM338_18915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM338_18925	COG0697	spore germination
AM338_18930	COG3738	Protein conserved in bacteria
AM338_18935	COG0371	Dehydrogenase
AM338_18940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM338_18945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_18945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_18945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM338_18950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_18955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_18965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM338_18970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM338_18975	COG2207	Transcriptional regulator
AM338_18980	COG2194	sulfuric ester hydrolase activity
AM338_19000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM338_19005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM338_19015	COG0583	DNA-binding transcription factor activity
AM338_19045	COG4206	TonB-dependent receptor
AM338_19075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM338_19080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM338_19080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM338_19125	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM338_19130	COG0250	Participates in transcription elongation, termination and antitermination
AM338_19175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM338_19185	COG2104	thiamine diphosphate biosynthetic process
AM338_19190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM338_19225	COG3068	Protein conserved in bacteria
AM338_19230	COG0776	regulation of translation
AM338_19240	COG3678	ATP-independent chaperone mediated protein folding
AM338_19250	COG4191	Histidine kinase
AM338_19255	COG2204	response regulator
AM338_19260	COG0151	Belongs to the GarS family
AM338_19300	COG0456	acetyltransferase
AM338_19310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM338_19315	COG2224	Isocitrate lyase
AM338_19330	COG1414	Transcriptional regulator
AM338_19335	COG1410	methionine synthase
AM338_19335	COG0646	methionine synthase
AM338_19340	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM338_19350	COG1187	pseudouridine synthase activity
AM338_19360	COG0527	aspartate kinase activity
AM338_19395	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM338_19410	COG0477	Major facilitator Superfamily
AM338_19410	COG2814	Major facilitator Superfamily
AM338_19415	COG3833	ABC-type maltose transport systems, permease component
AM338_19420	COG1175	transmembrane transport
AM338_19425	COG2182	Extracellular solute-binding protein
AM338_19435	COG3842	ATPase activity
AM338_19455	COG1357	PFAM Pentapeptide repeats (8 copies)
AM338_19480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM338_19490	COG0534	Mate efflux family protein
AM338_19495	COG3237	CsbD-like
AM338_19500	COG0735	belongs to the Fur family
AM338_19515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM338_19555	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM338_19595	COG1846	Transcriptional regulator
AM338_19605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM338_19610	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM338_19620	COG1403	HNH endonuclease
AM338_19660	COG3772	lysozyme
AM338_19705	COG0740	serine-type endopeptidase activity
AM338_19780	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM338_19800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM338_19810	COG0604	alcohol dehydrogenase
AM338_19815	COG0305	Participates in initiation and elongation during chromosome replication
AM338_19820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM338_19825	COG1448	Aminotransferase
AM338_19835	COG3700	Belongs to the class B bacterial acid phosphatase family
AM338_19840	COG0432	Pfam Uncharacterised protein family UPF0047
AM338_19845	COG2315	Protein conserved in bacteria
AM338_19850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM338_19860	COG0629	single-stranded DNA binding
AM338_19910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM338_19915	COG2207	Transcriptional regulator
AM338_19920	COG0789	Transcriptional regulator
AM338_19940	COG2252	PERMEase
AM338_19945	COG0025	NhaP-type Na H and K H
AM338_19950	COG1357	PFAM Pentapeptide repeats (8 copies)
AM338_19960	COG3162	membrane
AM338_19965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM338_19980	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AM338_19985	COG0437	4 iron, 4 sulfur cluster binding
AM338_19990	COG3301	Polysulphide reductase, NrfD
AM338_19995	COG1138	Cytochrome C-type biogenesis protein
AM338_20000	COG3088	subunit of a heme lyase
AM338_20005	COG4235	cytochrome complex assembly
AM338_20015	COG1301	dicarboxylic acid transport
AM338_20020	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM338_20030	COG1538	Outer membrane efflux protein
AM338_20035	COG1289	transmembrane transporter activity
AM338_20040	COG1566	PFAM secretion protein HlyD family protein
AM338_20050	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM338_20055	COG1940	carbohydrate kinase activity
AM338_20060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM338_20065	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_20070	COG1129	ABC transporter
AM338_20075	COG1879	ABC-type sugar transport system periplasmic component
AM338_20080	COG1737	Transcriptional regulator
AM338_20090	COG0698	ribose 5-phosphate isomerase
AM338_20100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM338_20105	COG0456	acetyltransferase
AM338_20110	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM338_20115	COG3454	Phosphonate metabolism
AM338_20120	COG4778	phosphonate C-P lyase system protein PhnL
AM338_20125	COG4107	phosphonate C-P lyase system protein PhnK
AM338_20130	COG3627	carbon phosphorus lyase activity
AM338_20135	COG3626	phosphonate metabolism
AM338_20140	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM338_20145	COG3624	Phosphonate C-P lyase system protein PhnG
AM338_20150	COG2188	Transcriptional regulator
AM338_20160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM338_20165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM338_20170	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM338_20175	COG2824	Alkylphosphonate utilization operon protein PhnA
AM338_20195	COG0477	Major facilitator Superfamily
AM338_20205	COG0642	Histidine kinase
AM338_20210	COG0745	RESPONSE REGULATOR receiver
AM338_20215	COG2194	sulfuric ester hydrolase activity
AM338_20220	COG0531	amino acid
AM338_20225	COG2207	Transcriptional regulator
AM338_20230	COG1982	Orn Lys Arg decarboxylase major
AM338_20235	COG2169	Transcriptional regulator
AM338_20240	COG1486	melibiose metabolic process
AM338_20245	COG2211	Major facilitator Superfamily
AM338_20250	COG3647	Membrane
AM338_20255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM338_20255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM338_20260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM338_20270	COG4565	transcriptional regulatory protein
AM338_20275	COG3290	protein histidine kinase activity
AM338_20280	COG3592	Divergent 4Fe-4S mono-cluster
AM338_20285	COG2388	GCN5-related N-acetyl-transferase
AM338_20305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM338_20310	COG3104	oligopeptide transport
AM338_20315	COG1982	Orn Lys Arg decarboxylase major
AM338_20320	COG0531	amino acid
AM338_20325	COG3710	Transcriptional regulator
AM338_20340	COG1309	transcriptional regulator
AM338_20345	COG4232	protein-disulfide reductase activity
AM338_20355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM338_20360	COG1027	Aspartate ammonia-lyase
AM338_20365	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM338_20370	COG0531	amino acid
AM338_20395	COG1509	lysine 2,3-aminomutase activity
AM338_20405	COG5510	response to toxic substance
AM338_20410	COG5510	response to toxic substance
AM338_20415	COG2076	Multidrug Resistance protein
AM338_20420	COG3040	lipid binding
AM338_20425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM338_20440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM338_20445	COG1053	succinate dehydrogenase
AM338_20455	COG0531	amino acid
AM338_20470	COG3264	Mechanosensitive ion channel
AM338_20470	COG1511	domain protein
AM338_20510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM338_20515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM338_20515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM338_20520	COG0802	atpase or kinase
AM338_20525	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM338_20545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM338_20550	COG0330	HflC and HflK could
AM338_20555	COG0330	HflC and HflK could
AM338_20560	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM338_20575	COG0557	exoribonuclease II activity
AM338_20580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM338_20585	COG1414	Transcriptional regulator
AM338_20590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM338_20595	COG2271	Major facilitator Superfamily
AM338_20600	COG2721	sulfolactate sulfo-lyase activity
AM338_20620	COG3766	membrane
AM338_20625	COG5463	Belongs to the UPF0441 family
AM338_20630	COG0754	glutathionylspermidine amidase activity
AM338_20635	COG1960	acyl-CoA dehydrogenase activity
AM338_20650	COG3650	response to hydrogen peroxide
AM338_20655	COG1073	alpha beta
AM338_20675	COG3414	Phosphotransferase system galactitol-specific IIB component
AM338_20680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_20695	COG0235	Class ii aldolase
AM338_20700	COG3477	response to acidic pH
AM338_20740	COG1943	Transposase
AM338_20745	COG0675	Transposase, IS605 OrfB family
AM338_20755	COG3061	Opacity-associated protein A
AM338_20765	COG0545	Peptidyl-prolyl cis-trans isomerase
AM338_20770	COG1113	amino acid transport
AM338_20780	COG0697	spore germination
AM338_20785	COG0702	epimerase
AM338_20790	COG1733	regulation of RNA biosynthetic process
AM338_20795	COG0737	Belongs to the 5'-nucleotidase family
AM338_20800	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM338_20815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM338_20825	COG1253	flavin adenine dinucleotide binding
AM338_20840	COG0729	surface antigen
AM338_20845	COG2911	Protein conserved in bacteria
AM338_20850	COG2105	PFAM AIG2 family protein
AM338_20855	COG2336	PFAM SpoVT AbrB
AM338_20860	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM338_20865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM338_20870	COG1879	ABC-type sugar transport system periplasmic component
AM338_20875	COG1129	ABC transporter
AM338_20880	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_20885	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM338_20895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM338_20905	COG0312	modulator of DNA gyrase
AM338_20910	COG3783	Cytochrome b(562)
AM338_20915	COG0602	queuosine metabolic process
AM338_20920	COG1328	CTP reductase activity
AM338_20925	COG0366	Alpha amylase catalytic
AM338_20930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM338_20930	COG1263	PTS System
AM338_20935	COG1609	Transcriptional regulator
AM338_20940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM338_20945	COG0251	oxidation-reduction process
AM338_20970	COG0251	oxidation-reduction process
AM338_20975	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_20980	COG1309	transcriptional regulator
AM338_20985	COG2731	YhcH YjgK YiaL family protein
AM338_21000	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM338_21005	COG0456	acetyltransferase
AM338_21015	COG0525	valine-tRNA ligase activity
AM338_21020	COG2927	DNA polymerase III (CHI subunit)
AM338_21030	COG0795	lipopolysaccharide-transporting ATPase activity
AM338_21035	COG0795	lipopolysaccharide-transporting ATPase activity
AM338_21040	COG0433	COG0433 Predicted ATPase
AM338_21045	COG1064	alcohol dehydrogenase
AM338_21055	COG0582	viral genome integration into host DNA
AM338_21135	COG3344	reverse transcriptase
AM338_21155	COG1309	transcriptional regulator
AM338_21165	COG4325	translation initiation factor activity
AM338_21175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM338_21190	COG2990	Protein conserved in bacteria
AM338_21195	COG0297	glycogen (starch) synthase activity
AM338_21200	COG0726	polysaccharide deacetylase
AM338_21215	COG3344	reverse transcriptase
AM338_21225	COG2085	NADP oxidoreductase coenzyme F420-dependent
AM338_21230	COG1120	ATPase activity
AM338_21235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM338_21240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM338_21245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM338_21250	COG4772	TonB-dependent receptor
AM338_21255	COG3712	iron ion homeostasis
AM338_21260	COG1595	DNA-templated transcription, initiation
AM338_21300	COG4372	Transposase
AM338_21305	COG3436	PFAM IS66 Orf2 family protein
AM338_21335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM338_21360	COG2610	gluconate transmembrane transporter activity
AM338_21375	COG0246	Mannitol dehydrogenase
AM338_21385	COG2186	Transcriptional regulator
AM338_21405	COG0583	DNA-binding transcription factor activity
AM338_21410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM338_21415	COG0700	Nucleoside recognition
AM338_21420	COG3366	ferrous iron transmembrane transporter activity
AM338_21430	COG0477	Major facilitator Superfamily
AM338_21445	COG1924	4 iron, 4 sulfur cluster binding
AM338_21450	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM338_21455	COG2733	membrane
AM338_21460	COG2814	Major facilitator Superfamily
AM338_21480	COG0523	cobalamin synthesis protein
AM338_21485	COG2879	small protein
AM338_21490	COG1966	Carbon starvation protein
AM338_21500	COG0840	transmembrane signaling receptor activity
AM338_21505	COG2271	Major facilitator Superfamily
AM338_21510	COG1802	Transcriptional regulator
AM338_21515	COG1063	alcohol dehydrogenase
AM338_21530	COG1484	DNA-dependent DNA replication
AM338_21545	COG2966	Psort location CytoplasmicMembrane, score
AM338_21550	COG2197	response regulator
AM338_21555	COG2197	response regulator
AM338_21560	COG4114	ferric iron reductase
AM338_21590	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM338_21595	COG0456	acetyltransferase
AM338_21600	COG1011	Hydrolase
AM338_21610	COG2823	Periplasmic or secreted lipoprotein
AM338_21620	COG4667	esterase of the alpha-beta hydrolase superfamily
AM338_21625	COG0084	hydrolase, TatD family'
AM338_21630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM338_21635	COG1328	CTP reductase activity
AM338_21670	COG0560	Phosphoserine phosphatase
AM338_21675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM338_21680	COG1056	cytidyltransferase-related domain
AM338_21680	COG3172	ATPase kinase involved in NAD metabolism
AM338_21685	COG0488	(ABC) transporter
AM338_21695	COG0741	lytic transglycosylase activity
AM338_21715	COG2207	Transcriptional regulator
AM338_21715	COG3708	Transcriptional regulator
AM338_21720	COG3045	CreA protein
AM338_21725	COG0745	RESPONSE REGULATOR receiver
AM338_21730	COG2205	protein histidine kinase activity
AM338_21735	COG4452	Inner membrane protein CreD
AM338_21740	COG0745	RESPONSE REGULATOR receiver
AM338_21750	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM338_21760	COG0527	aspartate kinase activity
AM338_21760	COG0460	homoserine dehydrogenase
AM338_21770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM338_21780	COG3022	response to hydroperoxide
AM338_21785	COG1115	amino acid carrier protein
AM338_21795	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM338_21800	COG1584	GPR1 FUN34 yaaH family protein
AM338_21805	COG4735	regulation of single-species biofilm formation
AM338_21825	COG3385	transposase activity
AM338_21845	COG0583	DNA-binding transcription factor activity
AM338_21875	COG0196	riboflavin kinase activity
AM338_21890	COG1047	Peptidyl-prolyl cis-trans
AM338_21915	COG0505	Belongs to the CarA family
AM338_21920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM338_21975	COG0644	oxidoreductase
AM338_21980	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM338_21985	COG2271	Major facilitator Superfamily
AM338_22000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM338_22025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM338_22030	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM338_22035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM338_22045	COG0564	pseudouridine synthase activity
AM338_22055	COG0417	DNA replication proofreading
AM338_22060	COG0235	Class ii aldolase
AM338_22065	COG2160	L-arabinose isomerase activity
AM338_22070	COG1069	ribulokinase activity
AM338_22080	COG4977	sequence-specific DNA binding
AM338_22085	COG0586	Pfam SNARE associated Golgi protein
AM338_22090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM338_22095	COG1178	ABC-type Fe3 transport system permease component
AM338_22100	COG4143	(ABC) transporter
AM338_22105	COG4533	DNA binding
AM338_22115	COG2814	Major facilitator Superfamily
AM338_22130	COG0473	3-isopropylmalate dehydrogenase activity
AM338_22145	COG0583	DNA-binding transcription factor activity
AM338_22150	COG0028	Belongs to the TPP enzyme family
AM338_22155	COG0440	acetolactate synthase activity
AM338_22165	COG1609	Transcriptional regulator
AM338_22175	COG2001	Belongs to the MraZ family
AM338_22185	COG3116	cell division
AM338_22190	COG0768	penicillin binding
AM338_22195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM338_22200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM338_22210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM338_22215	COG0772	Belongs to the SEDS family
AM338_22230	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM338_22235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM338_22240	COG0849	cell division
AM338_22245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM338_22265	COG0494	nUDIX hydrolase
AM338_22280	COG0237	dephospho-CoA kinase activity
AM338_22290	COG1459	type II secretion system
AM338_22295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM338_22300	COG4969	Belongs to the N-Me-Phe pilin family
AM338_22310	COG0157	Belongs to the NadC ModD family
AM338_22315	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM338_22320	COG3725	Membrane protein required for beta-lactamase induction
AM338_22325	COG1113	amino acid transport
AM338_22330	COG2186	Transcriptional regulator
AM338_22340	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM338_22345	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM338_22350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM338_22355	COG3064	Membrane
AM338_22365	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM338_22390	COG2132	Multicopper oxidase
AM338_22395	COG4993	Dehydrogenase
AM338_22400	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AM338_22405	COG0288	reversible hydration of carbon dioxide
AM338_22410	COG1131	(ABC) transporter
AM338_22415	COG0842	Transport permease protein
AM338_22420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM338_22425	COG0726	polysaccharide deacetylase
AM338_22445	COG5464	transposase or invertase
AM338_22460	COG3539	Fimbrial protein
AM338_22465	COG3539	Fimbrial protein
AM338_22470	COG3539	Fimbrial protein
AM338_22475	COG3539	Fimbrial protein
AM338_22480	COG3188	usher protein
AM338_22485	COG3121	Chaperone
AM338_22490	COG3539	Fimbrial protein
AM338_22495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM338_22500	COG0617	tRNA 3'-terminal CCA addition
AM338_22510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM338_22520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM338_22525	COG1643	Atp-dependent helicase
AM338_22535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM338_22540	COG4774	siderophore transport
AM338_22545	COG1120	ATPase activity
AM338_22550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM338_22555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM338_22575	COG2860	membrane
AM338_22580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM338_22600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM338_22605	COG3835	regulator
AM338_22615	COG1408	metallophosphoesterase
AM338_22630	COG0024	Methionine aminopeptidase
AM338_22665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM338_22670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM338_22675	COG0575	Belongs to the CDS family
AM338_22680	COG0750	zinc metalloprotease
AM338_22690	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM338_22695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM338_22720	COG0587	DNA-directed DNA polymerase activity
AM338_22735	COG0346	lactoylglutathione lyase activity
AM338_22740	COG0037	tRNA processing
AM338_22745	COG4568	rho-dependent transcription termination
AM338_22755	COG4681	YaeQ
AM338_22760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM338_22765	COG3015	lipoprotein NlpE involved in copper resistance
AM338_22770	COG0791	NLP P60 protein
AM338_22780	COG1720	tRNA m6t6A37 methyltransferase activity
AM338_22790	COG1464	Belongs to the NlpA lipoprotein family
AM338_22795	COG2011	ABC-type metal ion transport system permease component
AM338_22800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM338_22805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM338_22840	COG0656	L-ascorbic acid biosynthetic process
AM338_22845	COG0583	DNA-binding transcription factor activity
AM338_22855	COG2226	methyltransferase
AM338_22860	COG0741	lytic transglycosylase activity
AM338_22860	COG1388	LysM domain
AM338_22865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM338_22870	COG2226	methyltransferase
AM338_22880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM338_22900	COG4104	PAAR repeat-containing protein
AM338_22905	COG3157	Type VI secretion system effector, Hcp
AM338_22995	COG3501	Rhs element vgr protein
AM338_23010	COG5433	transposase activity
AM338_23015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM338_23025	COG1960	acyl-CoA dehydrogenase activity
AM338_23035	COG0121	glutamine amidotransferase
AM338_23040	COG3034	peptidoglycan biosynthetic process
AM338_23045	COG3041	Addiction module toxin RelE StbE family
AM338_23050	COG3077	Addiction module antitoxin, RelB DinJ family
AM338_23055	COG0791	NLP P60 protein
AM338_23060	COG1943	Transposase
AM338_23080	COG2161	toxin-antitoxin pair type II binding
AM338_23090	COG0454	-acetyltransferase
AM338_23095	COG1690	Belongs to the RtcB family
AM338_23100	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM338_23105	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM338_23125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM338_23145	COG0582	viral genome integration into host DNA
AM338_23190	COG3811	Belongs to the UPF0386 family
AM338_23205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM338_23215	COG1879	ABC-type sugar transport system periplasmic component
AM338_23265	COG3344	reverse transcriptase
AM338_23295	COG4372	Transposase
AM338_23300	COG3436	PFAM IS66 Orf2 family protein
AM338_23410	COG2020	methyltransferase activity
AM338_23440	COG2003	Belongs to the UPF0758 family
AM338_23465	COG0583	DNA-binding transcription factor activity
AM338_23470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM338_23475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM338_23480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM338_23485	COG2080	2 iron, 2 sulfur cluster binding
AM338_23495	COG3477	response to acidic pH
AM338_23510	COG3121	Chaperone
AM338_23520	COG3188	usher protein
AM338_23555	COG0254	rRNA binding
AM338_23575	COG1388	LysM domain
AM338_23585	COG2207	Transcriptional regulator
AM338_23585	COG3708	Transcriptional regulator
AM338_23590	COG3059	membrane
AM338_23600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM338_23605	COG2207	Transcriptional regulator
AM338_23610	COG0247	lactate metabolic process
AM338_23615	COG1139	Iron-sulfur cluster binding protein
AM338_23620	COG1556	Lactate utilization protein
AM338_23660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM338_23675	COG2771	luxR family
AM338_23675	COG2200	EAL domain
AM338_23680	COG0583	DNA-binding transcription factor activity
AM338_23695	COG0666	response to abiotic stimulus
AM338_23705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM338_23710	COG1304	FMN binding
AM338_23720	COG0549	Belongs to the carbamate kinase family
AM338_23725	COG0402	S-adenosylhomocysteine deaminase activity
AM338_23730	COG1064	alcohol dehydrogenase
AM338_23745	COG1280	lysine exporter protein (LysE YggA)
AM338_23755	COG3829	transcription factor binding
AM338_23760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM338_23765	COG0372	Belongs to the citrate synthase family
AM338_23770	COG2079	MmgE PrpD family protein
AM338_23775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM338_23780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM338_23785	COG0402	S-adenosylhomocysteine deaminase activity
AM338_23790	COG0583	DNA-binding transcription factor activity
AM338_23795	COG0288	reversible hydration of carbon dioxide
AM338_23805	COG2807	transmembrane transport
AM338_23810	COG0110	maltose O-acetyltransferase activity
AM338_23815	COG2223	nitrite transmembrane transporter activity
AM338_23820	COG3250	beta-galactosidase activity
AM338_23830	COG1609	Transcriptional regulator
AM338_23835	COG1414	Transcriptional regulator
AM338_23845	COG3384	dioxygenase
AM338_23855	COG3971	2-oxopent-4-enoate hydratase activity
AM338_23870	COG2814	Major facilitator Superfamily
AM338_23875	COG3122	Protein conserved in bacteria
AM338_23905	COG1215	transferase activity, transferring glycosyl groups
AM338_23910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM338_23930	COG4521	taurine ABC transporter
AM338_23935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM338_23940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM338_23945	COG2175	clavaminate synthase activity
AM338_23950	COG0113	porphobilinogen synthase activity
AM338_23960	COG3468	outer membrane autotransporter barrel domain protein
AM338_23965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM338_23970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM338_23980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM338_24000	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM338_24015	COG1785	Belongs to the alkaline phosphatase family
AM338_24025	COG3706	GGDEF domain
AM338_24030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM338_24055	COG4126	flavin adenine dinucleotide binding
AM338_24080	COG1940	carbohydrate kinase activity
AM338_24085	COG2814	Major facilitator Superfamily
AM338_24090	COG0419	ATPase involved in DNA repair
AM338_24095	COG0420	3'-5' exonuclease activity
AM338_24100	COG0745	RESPONSE REGULATOR receiver
AM338_24105	COG5002	protein histidine kinase activity
AM338_24110	COG1114	Component of the transport system for branched-chain amino acids
AM338_24115	COG1113	amino acid transport
AM338_24120	COG0366	Alpha amylase catalytic
AM338_24140	COG1862	Preprotein translocase
AM338_24145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM338_24150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM338_24155	COG1403	HNH endonuclease
AM338_24160	COG3248	Nucleoside-binding outer membrane protein
AM338_24165	COG4238	major outer membrane lipoprotein
AM338_24175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM338_24175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM338_24190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM338_24195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM338_24200	COG0667	Aldo Keto reductase
AM338_24210	COG0142	geranyltranstransferase activity
AM338_24225	COG0693	protein deglycase activity
AM338_24230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM338_24240	COG2814	Major facilitator Superfamily
AM338_24250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM338_24255	COG1845	cytochrome c oxidase, subunit III
AM338_24260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM338_24265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM338_24270	COG2223	nitrite transmembrane transporter activity
AM338_24275	COG3056	Lipoprotein
AM338_24285	COG0271	Belongs to the BolA IbaG family
AM338_24310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM338_24315	COG0776	regulation of translation
AM338_24320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM338_24325	COG1555	photosystem II stabilization
AM338_24330	COG0824	Thioesterase
AM338_24340	COG4533	DNA binding
AM338_24350	COG1522	sequence-specific DNA binding
AM338_24355	COG1132	(ABC) transporter
AM338_24360	COG1132	(ABC) transporter
AM338_24365	COG0347	Belongs to the P(II) protein family
AM338_24370	COG0004	ammonium transporteR
AM338_24375	COG1946	Acyl-CoA thioesterase
AM338_24380	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM338_24385	COG3695	enzyme binding
AM338_24395	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM338_24400	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM338_24410	COG0110	maltose O-acetyltransferase activity
AM338_24425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM338_24430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM338_24435	COG1309	transcriptional regulator
AM338_24445	COG1196	nuclear chromosome segregation
AM338_24445	COG3264	Mechanosensitive ion channel
AM338_24455	COG3923	Primosomal replication protein n
AM338_24460	COG2832	Protein of unknown function (DUF454)
AM338_24475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM338_24490	COG0326	Molecular chaperone. Has ATPase activity
AM338_24515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM338_24520	COG4651	solute:proton antiporter activity
AM338_24520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM338_24525	COG2223	nitrite transmembrane transporter activity
AM338_24535	COG0737	Belongs to the 5'-nucleotidase family
AM338_24540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM338_24550	COG3735	TraB family
AM338_24560	COG3093	addiction module antidote protein HigA
AM338_24565	COG2217	Heavy metal translocating P-type atpase
AM338_24570	COG2066	Belongs to the glutaminase family
AM338_24575	COG0531	amino acid
AM338_24580	COG0789	Transcriptional regulator
AM338_24585	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM338_24590	COG0330	HflC and HflK could
AM338_24595	COG4619	ABC transporter
AM338_24600	COG0390	transport system, permease component
AM338_24605	COG3118	belongs to the thioredoxin family
AM338_24610	COG0300	oxidoreductase activity
AM338_24615	COG2755	lipolytic protein G-D-S-L family
AM338_24620	COG4181	ATPase activity
AM338_24625	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM338_24660	COG0583	DNA-binding transcription factor activity
AM338_24665	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM338_24670	COG1414	Transcriptional regulator
AM338_24675	COG3960	tartronate-semialdehyde synthase activity
AM338_24680	COG3622	Belongs to the hyi family
AM338_24685	COG2084	Dehydrogenase
AM338_24690	COG1953	Uracil, thiamine, allantoin
AM338_24700	COG2233	PERMEase
AM338_24705	COG1929	Belongs to the glycerate kinase type-1 family
AM338_24710	COG3257	ureidoglycine aminohydrolase activity
AM338_24715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM338_24720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM338_24725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM338_24730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM338_24740	COG0549	Belongs to the carbamate kinase family
AM338_24745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM338_24750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM338_24765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM338_24775	COG1988	membrane-bound metal-dependent
AM338_24780	COG2501	S4 domain
AM338_24790	COG3539	Fimbrial protein
AM338_24795	COG3121	Chaperone
AM338_24800	COG3188	usher protein
AM338_24805	COG3539	Fimbrial protein
AM338_24810	COG3539	Fimbrial protein
AM338_24815	COG2197	response regulator
AM338_25130	COG1475	DNA binding
AM338_25135	COG1192	Involved in chromosome partitioning
AM338_25155	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
AM338_25240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM338_25250	COG0148	phosphopyruvate hydratase activity
AM338_25260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM338_25265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM338_25270	COG1121	(ABC) transporter
AM338_25350	COG4771	TonB-dependent receptor
AM338_25380	COG3436	PFAM IS66 Orf2 family protein
AM338_25385	COG3316	Transposase and inactivated derivatives
AM338_25405	COG3316	Transposase and inactivated derivatives
AM338_25420	COG1660	Displays ATPase and GTPase activities
AM338_25430	COG3316	Transposase and inactivated derivatives
AM338_25460	COG3316	Transposase and inactivated derivatives
AM338_25495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM338_25500	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM338_25510	COG0672	)-iron permease
AM338_25525	COG0577	efflux transmembrane transporter activity
AM338_25525	COG1136	(ABC) transporter
AM338_25530	COG1136	(ABC) transporter
AM338_25530	COG0577	efflux transmembrane transporter activity
AM338_25535	COG0577	efflux transmembrane transporter activity
AM338_25535	COG1136	(ABC) transporter
AM338_25560	COG3316	Transposase and inactivated derivatives
AM338_25575	COG3344	reverse transcriptase
AM338_25670	COG3344	reverse transcriptase
AM338_25700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM338_25705	COG1028	Short-chain dehydrogenase reductase Sdr
AM338_25710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AM338_25715	COG1902	pentaerythritol trinitrate reductase activity
AM338_25725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM338_25745	COG3316	Transposase and inactivated derivatives
AM338_25770	COG0697	spore germination
AM338_25790	COG4644	lycopene metabolic process
AM338_25860	COG3436	PFAM IS66 Orf2 family protein
AM338_25880	COG1288	antiporter activity
AM338_25895	COG2235	arginine
AM338_25950	COG4372	Transposase
AM338_25955	COG3436	PFAM IS66 Orf2 family protein
AM338_25960	COG2963	transposase activity
AM338_26095	COG3344	reverse transcriptase
AM338_26240	COG3344	reverse transcriptase
AM338_26260	COG3316	Transposase and inactivated derivatives
AM338_26270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM338_26285	COG3316	Transposase and inactivated derivatives
AM338_26315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM338_26340	COG3316	Transposase and inactivated derivatives
AM338_26350	COG0840	transmembrane signaling receptor activity
AM338_26385	COG3316	Transposase and inactivated derivatives
AM338_26405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM338_26410	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM338_26580	COG0330	HflC and HflK could
AM338_26680	COG3451	type IV secretory pathway VirB4
AM338_26705	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AM338_26730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
