locus-tag class description CEJ55_00015 ENOG4105D5K Hemolysin activator protein CEJ55_00100 ENOG4105F4K antigen 43 CEJ55_00115 ENOG4106H6R UPF0380 protein CEJ55_00120 ENOG4106549 Antirestriction protein CEJ55_00125 ENOG4108YGG dna repair protein CEJ55_00130 ENOG4106WJE Protein of unknown function (DUF987) CEJ55_00135 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles CEJ55_00160 ENOG4105BZU Histidine kinase CEJ55_00175 ENOG4108M3R transcriptional activator CadC CEJ55_00180 ENOG4105D5Q Arginine ornithine antiporter CEJ55_00185 ENOG4105CXN decarboxylase CEJ55_00190 ENOG4105DUX Transporter CEJ55_00195 ENOG4105CRK lysyL-tRNA synthetase CEJ55_00215 ENOG410830R acetyltransferase CEJ55_00220 ENOG4105VR1 Pfam:DUF1271 CEJ55_00225 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CEJ55_00230 ENOG4108MRH transcriptional regulatory protein CEJ55_00240 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CEJ55_00245 ENOG4107GFK fumarate CEJ55_00250 ENOG4108R5S membrane CEJ55_00255 ENOG4105CT4 transporter CEJ55_00260 ENOG4105F8D glycoside hydrolase family 4 CEJ55_00270 ENOG4108K2B transcriptional regulator CEJ55_00275 ENOG4105CXN decarboxylase CEJ55_00280 ENOG4106ZGR Transcriptional regulator CEJ55_00285 ENOG4105D5Q Arginine ornithine antiporter CEJ55_00290 ENOG4105DIJ Phosphoethanolamine transferase CEJ55_00295 ENOG4105XJC Two component transcriptional regulator (Winged helix family CEJ55_00300 ENOG4105ECM Sensor protein basS pmrB CEJ55_00310 ENOG4105CSH Transporter CEJ55_00315 ENOG4108YIV CEJ55_00320 ENOG4108F5E vimentin CEJ55_00330 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CEJ55_00335 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase CEJ55_00340 ENOG4105D5T phosphonate abc transporter CEJ55_00345 ENOG4105EHI Phosphonate ABC transporter, periplasmic CEJ55_00355 ENOG4107RJJ Transcriptional regulator CEJ55_00360 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG CEJ55_00365 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH CEJ55_00370 ENOG4105EKV Phosphonate metabolism protein CEJ55_00375 ENOG4105FT8 Phosphonate metabolism CEJ55_00380 ENOG4105ENV phosphonate C-P lyase system protein PhnK CEJ55_00385 ENOG4105HRV phosphonate c-p lyase system protein phnl CEJ55_00390 ENOG4105FD8 phosphonate metabolism protein PhnM CEJ55_00395 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) CEJ55_00400 ENOG410849A acetyltransferase, (GNAT) family CEJ55_00405 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein CEJ55_00410 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 CEJ55_00415 ENOG4108YZG isomerase CEJ55_00420 ENOG4105EUZ Beta-lactamase domain protein CEJ55_00430 ENOG4105J12 Multidrug resistance protein mdtN CEJ55_00435 ENOG4108MI0 Resistance protein CEJ55_00440 ENOG4105ETP RND efflux system, outer membrane lipoprotein CEJ55_00450 ENOG41082ND Uncharacterized protein yjcO CEJ55_00455 ENOG4105CK2 sodium dicarboxylate symporter CEJ55_00465 ENOG4108W0S formate-dependent nitrite reductase complex CEJ55_00475 ENOG4108QKW cytochrome c-type biogenesis protein CEJ55_00480 ENOG4105DVI reductase, NrfD CEJ55_00485 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CEJ55_00490 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit CEJ55_00505 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CEJ55_00510 ENOG41062QD Membrane CEJ55_00525 ENOG4105EEQ Na H antiporter CEJ55_00530 ENOG4105C7N Xanthine uracil vitamin C permease CEJ55_00550 ENOG4108Z4X TRANSCRIPTIONal CEJ55_00555 ENOG4108W3Q Transcriptional regulator CEJ55_00560 ENOG4108M8H domain protein CEJ55_00570 ENOG4105PMV Membrane CEJ55_00575 ENOG4108UUM single-stranded DNA-binding protein CEJ55_00580 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CEJ55_00585 ENOG4105MSB protein, conserved in bacteria CEJ55_00590 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme CEJ55_00595 ENOG4105F0S class B acid phosphatase CEJ55_00605 ENOG4105CGF Aromatic amino acid aminotransferase CEJ55_00610 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEJ55_00615 ENOG4105CDU Replicative dna helicase CEJ55_00620 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CEJ55_00625 ENOG4105P4Z Phage shock protein G CEJ55_00630 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CEJ55_00645 ENOG4105MYN Zinc uptake regulation protein CEJ55_00650 ENOG4105VDW Csbd family CEJ55_00655 ENOG4107R73 Mate efflux family protein CEJ55_00665 ENOG41080IJ Diacylglycerol kinase CEJ55_00700 ENOG4107W52 maltose operon periplasmic protein CEJ55_00710 ENOG4108IJ9 (ABC) transporter CEJ55_00720 ENOG4107FKK extracellular solute-binding protein family 1 CEJ55_00725 ENOG4105D56 permease protein CEJ55_00730 ENOG4105EG2 ABC transporter, permease CEJ55_00735 ENOG4107QNK )-transporter CEJ55_00750 ENOG4105E3R (LipO)protein CEJ55_00755 ENOG4108Q9C Periplasmic Protein CEJ55_00760 ENOG4108MDC (LipO)protein CEJ55_00785 ENOG4105CFH Aspartokinase CEJ55_00790 ENOG4108WZA zeta toxin CEJ55_00795 ENOG410756H nucleotidyltransferase CEJ55_00805 ENOG4108ZR5 Conserved Protein CEJ55_00810 ENOG4105FE9 pseudouridine synthase CEJ55_00820 ENOG4105EAM Na Pi-cotransporter CEJ55_00825 ENOG4105C3R Methionine synthase CEJ55_00830 ENOG41069M3 Transcriptional regulator CEJ55_00845 ENOG4108I9X Isocitrate lyase CEJ55_00850 ENOG4107QP3 malate synthase g CEJ55_00860 ENOG4105K5X acetyltransferase CEJ55_00895 ENOG4105C12 Phosphoribosylglycinamide synthetase CEJ55_00900 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEJ55_00905 ENOG4105BZU Histidine kinase CEJ55_00915 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism CEJ55_00920 ENOG4108T8B Protein of unknown function (DUF1481) CEJ55_00925 ENOG4105K70 DNA-binding protein CEJ55_00930 ENOG4105R2J Conserved Protein CEJ55_00965 ENOG4105D06 uba thif-type nad fad binding protein CEJ55_00970 ENOG4105WHD thiamine biosynthesis protein ThiS CEJ55_00980 ENOG4105D41 biosynthesis protein thiH CEJ55_00985 ENOG410645W Thiamin biosynthesis protein ThiH CEJ55_01025 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CEJ55_01030 ENOG4105PM1 preprotein translocase subunit SecE CEJ55_01075 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CEJ55_01080 ENOG4105D4A Cell wall formation (By similarity) CEJ55_01110 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) CEJ55_01120 ENOG4108Y73 Membrane CEJ55_01140 ENOG4105C5Q Transcriptional regulator CEJ55_01145 ENOG4108I5G Major Facilitator superfamily CEJ55_01150 ENOG4105CXK mandelate racemase muconate lactonizing CEJ55_01160 ENOG4105CAS nag kinase CEJ55_01165 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase CEJ55_01180 ENOG4105DIJ Phosphoethanolamine transferase CEJ55_01185 ENOG4106R3P AraC family transcriptional regulator CEJ55_01190 ENOG4108XCZ PTS System CEJ55_01195 ENOG4108AHH pyruvate formate lyase II activase CEJ55_01200 ENOG4105C6N Formate acetyltransferase CEJ55_01205 ENOG4108YRF PTS System CEJ55_01210 ENOG4105DM4 PTS System CEJ55_01215 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CEJ55_01220 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEJ55_01225 ENOG4105DCT glycerol dehydrogenase CEJ55_01230 ENOG4108XC3 NADH ubiquinone oxidoreductase CEJ55_01235 ENOG4108Q5Y Membrane CEJ55_01240 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) CEJ55_01245 ENOG4105SYT Methylenetetrahydrofolate reductase CEJ55_01250 ENOG4105CFH Aspartokinase CEJ55_01255 ENOG4105C28 cystathionine CEJ55_01300 ENOG4105C25 Primosomal protein n' CEJ55_01305 ENOG4105ETE Transcriptional regulator (LacI family CEJ55_01310 ENOG41063M6 Cell Division Protein CEJ55_01325 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CEJ55_01340 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CEJ55_01350 ENOG4105CBT Fructose-1,6-bisphosphatase CEJ55_01355 ENOG4105DP0 ferredoxin-NADP reductase CEJ55_01365 ENOG41065TG regulatoR CEJ55_01370 ENOG4108VTS Membrane CEJ55_01375 ENOG4105EBK exported protein CEJ55_01395 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CEJ55_01410 ENOG4105FMW periplasmic CEJ55_01415 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEJ55_01420 ENOG4105E0F Histidine kinase CEJ55_01440 ENOG4108RPX mosc domain containing protein CEJ55_01455 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEJ55_01495 ENOG41064BA PTS system, fructose-specific, IIA component CEJ55_01500 ENOG4105DM4 PTS System CEJ55_01505 ENOG4105CN9 Peptidase m42 family protein CEJ55_01510 ENOG4106C3V frv operon regulatory protein CEJ55_01515 ENOG4108V87 frv operon regulatory protein CEJ55_01530 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEJ55_01535 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEJ55_01540 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CEJ55_01545 ENOG4108MG3 formate dehydrogenase CEJ55_01555 ENOG41068KX affects formate dehydrogenase-N CEJ55_01560 ENOG4106UEE Transcriptional regulator CEJ55_01575 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system CEJ55_01585 ENOG4105SUU thioesterase domain CEJ55_01600 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CEJ55_01605 ENOG4105E98 transcriptional regulator DeoR family CEJ55_01610 ENOG4108MGF sugar kinase CEJ55_01615 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CEJ55_01620 ENOG4105D2M Aldolase CEJ55_01625 ENOG4107QKS N-acylglucosamine 2-epimerase CEJ55_01630 ENOG4107WI4 Aldose-1-epimerase CEJ55_01635 ENOG4105CJQ hydrolase, family 31 CEJ55_01640 ENOG4105CT4 transporter CEJ55_01645 ENOG4105CT4 transporter CEJ55_01650 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is CEJ55_01655 ENOG4105R9B Major Facilitator CEJ55_01660 ENOG4108KHF Resistance protein CEJ55_01665 ENOG4108K85 Transcriptional regulator CEJ55_01680 ENOG4105C5F glutamine synthetase CEJ55_01685 ENOG4105CUX Signal transduction histidine kinase CEJ55_01690 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEJ55_01695 ENOG4106FIY CEJ55_01700 ENOG4105D4P Coproporphyrinogen iii oxidase CEJ55_01720 ENOG4105C2M dna polymerase I CEJ55_01730 ENOG4106HNH Acyl-transferase CEJ55_01740 ENOG4108Z33 Thiol disulfide Interchange Protein CEJ55_01745 ENOG4105E27 serine threonine protein kinase CEJ55_01750 ENOG4105PC1 Conserved Protein CEJ55_01755 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) CEJ55_01760 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CEJ55_01790 ENOG4108RR8 protoporphyrinogen oxidase CEJ55_01795 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CEJ55_01800 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CEJ55_01815 ENOG4105CHU acetyl-coa acetyltransferase CEJ55_01820 ENOG4107QK7 reductase CEJ55_01825 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CEJ55_01830 ENOG4105MDZ Transcriptional activator rfaH CEJ55_01840 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CEJ55_01845 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) CEJ55_01850 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CEJ55_01860 ENOG4105JC1 sterol-binding domain protein CEJ55_01870 ENOG4105CGY Dna recombination protein CEJ55_01875 ENOG4108I5U Uridine phosphorylase CEJ55_01880 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CEJ55_01890 ENOG4105DZ2 Transcriptional regulator CEJ55_01895 ENOG4105EMK carboxylate amino acid amine transporter CEJ55_01900 ENOG4105DQF Hydrolase CEJ55_01905 ENOG4108EUD Lysophospholipase CEJ55_01920 ENOG4105C9U ATP-dependent DNA helicase RecQ CEJ55_01925 ENOG4105HDD phospholipase CEJ55_01930 ENOG4108VUY thioesterase Superfamily protein CEJ55_01935 ENOG4105FR1 rard protein CEJ55_01950 ENOG4107QUT magnesium and cobalt transport protein CorA CEJ55_01965 ENOG4107QUT magnesium and cobalt transport protein CorA CEJ55_01970 ENOG4108T58 Mg2 transport protein CorA CEJ55_01975 ENOG4105C4R Atp-dependent dna helicase CEJ55_01980 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CEJ55_01990 ENOG4105CT0 Protein of unknown function, DUF484 CEJ55_02000 ENOG4105S7Z (LipO)protein CEJ55_02025 ENOG4107T0K Adenylate cyclase CEJ55_02040 ENOG41076E6 Uroporphyrinogen-III Synthase CEJ55_02045 ENOG4105ECF c-methyltransferase CEJ55_02050 ENOG410601J HemY protein CEJ55_02055 ENOG4105C4X radical SAM domain protein CEJ55_02080 ENOG4105C85 amino acid CEJ55_02100 ENOG4105EGZ biosynthesis protein CEJ55_02105 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CEJ55_02110 ENOG4108WJ1 acetyltransferase CEJ55_02115 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CEJ55_02120 ENOG4105C1B dTDP-glucose 4-6-dehydratase CEJ55_02125 ENOG4108IJ1 Dehydrogenase CEJ55_02130 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CEJ55_02135 ENOG4105SFE lipopolysaccharide biosynthesis protein CEJ55_02140 ENOG4105ESV Glycosyl transferase, family 4 CEJ55_02160 ENOG4105K63 Thioredoxin CEJ55_02180 ENOG4105C4R Atp-dependent dna helicase CEJ55_02190 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CEJ55_02200 ENOG4105EMY transcriptional regulator CEJ55_02205 ENOG4105C7B Threonine dehydratase CEJ55_02215 ENOG4105CM2 brancheD-chain amino acid aminotransferase CEJ55_02220 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CEJ55_02235 ENOG4105C0P Mg chelatase subunit ChlI CEJ55_02240 ENOG4108WFC UPF0438 protein yifE CEJ55_02280 ENOG4107EJG GntR family transcriptional regulator CEJ55_02285 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEJ55_02290 ENOG4105ETE Transcriptional regulator (LacI family CEJ55_02295 ENOG4108RVA ribokinase CEJ55_02300 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEJ55_02305 ENOG4105CNN ABC, transporter CEJ55_02310 ENOG4105C2J ABC transporter CEJ55_02340 ENOG4108VVK transcriptional Regulator, AsnC CEJ55_02345 ENOG4105QTB Flavodoxin CEJ55_02360 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CEJ55_02370 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CEJ55_02415 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CEJ55_02420 ENOG4108RQP Major type 1 subunit fimbrin CEJ55_02430 ENOG4105CW0 outer membrane usher protein CEJ55_02440 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CEJ55_02445 ENOG4105C8U phosphate abc transporter CEJ55_02450 ENOG4105E2Z phosphate ABC transporter (Permease CEJ55_02455 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) CEJ55_02460 ENOG4108UTW Plays a role in the regulation of phosphate uptake CEJ55_02465 ENOG4105CID antiterminator CEJ55_02470 ENOG4105C5Y PTS System CEJ55_02475 ENOG4105CS2 ec 3.2.1.21 CEJ55_02485 ENOG4105DYC esterase CEJ55_02490 ENOG4107VKM 6-phosphogluconolactonase CEJ55_02495 ENOG4106611 bacteriocin immunity CEJ55_02505 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CEJ55_02510 ENOG4105C7N Xanthine uracil vitamin C permease CEJ55_02515 ENOG4108YYH Nadph-dependent fmn reductase CEJ55_02520 ENOG4105E8Q phosphopantetheinyl transferase CEJ55_02535 ENOG4108P6C Tryptophan transporter of low affinity CEJ55_02585 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CEJ55_02595 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEJ55_02600 ENOG4105VP5 Bacterial protein of unknown function (DUF937) CEJ55_02605 ENOG410667J hydrolase CEJ55_02610 ENOG410657R replicase EC 2.7 CEJ55_02615 ENOG4105EMF GntR family transcriptional regulator CEJ55_02620 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 CEJ55_02625 ENOG4108RTU Aldolase CEJ55_02635 ENOG4105DJB Major Facilitator Superfamily CEJ55_02645 ENOG4105D99 atp gtp-binding protein CEJ55_02650 ENOG4105R2A (LipO)protein CEJ55_02670 ENOG4105FDP GntR family transcriptional regulator CEJ55_02675 ENOG4105CI1 PTS System CEJ55_02690 ENOG4108AHD Transcriptional regulator CEJ55_02695 ENOG4107RUZ Sss sodium solute transporter superfamily CEJ55_02700 ENOG4105CBG Sulfatase CEJ55_02705 ENOG4106DRA Inner membrane protein YidI CEJ55_02710 ENOG4105VG5 Membrane CEJ55_02715 ENOG4105JP4 Inner membrane protein yidG CEJ55_02720 ENOG4105J13 transcriptional regulator CEJ55_02725 ENOG4105E5M Multidrug resistance protein D CEJ55_02760 ENOG4105C7K acetolactate synthase CEJ55_02765 ENOG4105M71 acetolactate synthase 1 regulatory subunit CEJ55_02770 ENOG4108KX4 response regulator CEJ55_02775 ENOG4105BZU Histidine kinase CEJ55_02780 ENOG4105CXY transporter CEJ55_02785 ENOG4105CXY transporter CEJ55_02795 ENOG4105C7N Xanthine uracil vitamin C permease CEJ55_02800 ENOG4108SAJ Protein of unknown function (DUF1198) CEJ55_02815 ENOG4105T8A Uncharacterized protein YicS CEJ55_02825 ENOG4105D01 (LipO)protein CEJ55_02830 ENOG4108UZ3 Transporter CEJ55_02835 ENOG4105S8Q sugar efflux transporter CEJ55_02850 ENOG4105CT4 transporter CEJ55_02855 ENOG4105CJQ hydrolase, family 31 CEJ55_02860 ENOG4105JV1 AsmA family CEJ55_02865 ENOG4105C2W permease CEJ55_02870 ENOG4105D6U Sodium Glutamate Symporter CEJ55_02875 ENOG4105CB5 ATP-dependent DNA helicase recG CEJ55_02880 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CEJ55_02885 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CEJ55_02890 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) CEJ55_02895 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) CEJ55_02905 ENOG4105EN6 Membrane CEJ55_02910 ENOG4105F5P DNA-damage-inducible protein d CEJ55_02915 ENOG4105DSJ YicC domain protein CEJ55_02945 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CEJ55_02960 ENOG4105W0E 50S ribosomal protein L33 CEJ55_02975 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CEJ55_02980 ENOG4105DKP glycosyl transferase, family 9 CEJ55_02985 ENOG4107RJ7 Glycosyl transferase (Group 1 CEJ55_02990 ENOG4107543 (lipo)polysaccharide CEJ55_02995 ENOG4106AH0 Glycosyl Transferase CEJ55_03000 ENOG4105X1N Glycosyl transferase family 8 CEJ55_03010 ENOG4105X1N Glycosyl transferase family 8 CEJ55_03015 ENOG4105K64 Glycosyl transferase, family 2 CEJ55_03020 ENOG41068PG O-Antigen polymerase CEJ55_03025 ENOG4105D16 lipopolysaccharide heptosyltransferase i CEJ55_03030 ENOG4105XA0 heptosyltransferase ii CEJ55_03040 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CEJ55_03050 ENOG4105K64 Glycosyl transferase, family 2 CEJ55_03055 ENOG4105PXI polysaccharide deacetylase CEJ55_03060 ENOG41063SB peptidase CEJ55_03075 ENOG4107YZP Rhodanese domain protein CEJ55_03080 ENOG4105VW4 glutaredoxin 3 CEJ55_03095 ENOG4105D7W serine acetyltransferase CEJ55_03100 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CEJ55_03110 ENOG41073TP transcriptional regulator CEJ55_03115 ENOG4105DAA L-lactate CEJ55_03120 ENOG4105EUR Domain-Containing protein CEJ55_03125 ENOG4108WY4 inner membrane lipoprotein CEJ55_03135 ENOG4108YYI Protein of unknown function (DUF2810) CEJ55_03145 ENOG4105E61 Mannitol repressor protein CEJ55_03155 ENOG4105CTS PTS system mannitol-specific CEJ55_03160 ENOG4105FP6 Protein of unknown function (DUF3302) CEJ55_03165 ENOG4105EFX secretion protein, HlyD family CEJ55_03210 ENOG4105CNA YD repeat protein CEJ55_03215 ENOG4108U78 Glutathione S-transferase CEJ55_03225 ENOG4105EM7 Selenocysteine-specific translation elongation factor CEJ55_03230 ENOG4105C0A alcohol dehydrogenase CEJ55_03235 ENOG4105C26 Dehydrogenase CEJ55_03245 ENOG4105KK7 inner membrane protein YiaW CEJ55_03250 ENOG4105EFX secretion protein, HlyD family CEJ55_03255 ENOG4108Q2M Transcriptional regulator CEJ55_03260 ENOG4105GNX MltA-interacting MipA family protein CEJ55_03270 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CEJ55_03275 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CEJ55_03280 ENOG4105H6Q decarboxylase CEJ55_03285 ENOG4105CMG Carbohydrate kinase CEJ55_03290 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CEJ55_03295 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CEJ55_03300 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter CEJ55_03305 ENOG4108R66 Conserved Protein CEJ55_03315 ENOG4105J4Q Transcriptional regulator CEJ55_03320 ENOG4108XIB electron transport protein ysaA CEJ55_03325 ENOG4105JKW Valine--pyruvate aminotransferase CEJ55_03330 ENOG4107T9C Alpha amylase catalytic region CEJ55_03335 ENOG4108UR8 BAX protein CEJ55_03340 ENOG4105T16 Transcriptional regulator (AraC family) CEJ55_03345 ENOG4107RNG ABC transporter CEJ55_03350 ENOG4105C2J ABC transporter CEJ55_03355 ENOG4105DFW ABC transporter CEJ55_03365 ENOG4105CMG Carbohydrate kinase CEJ55_03370 ENOG410688U Inner membrane protein yiaB CEJ55_03375 ENOG4108Z12 YiaAB two helix domain-containing protein CEJ55_03380 ENOG4105MEV Acyl-transferase CEJ55_03390 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit CEJ55_03400 ENOG41060TC Hok gef cell toxic protein CEJ55_03405 ENOG4105VEQ Cold shock protein CEJ55_03410 ENOG4105MVF Transcriptional regulator CEJ55_03415 ENOG4106JH6 (LipO)protein CEJ55_03425 ENOG4108ZG0 Ompa motb domain protein CEJ55_03430 ENOG4107QY8 reductase CEJ55_03435 ENOG4105HNP -acetyltransferase CEJ55_03440 ENOG4108R3E Dna-3-methyladenine glycosylase i CEJ55_03445 ENOG4105EAX Putative lipase CEJ55_03455 ENOG4105FCD Major Facilitator CEJ55_03460 ENOG4106EAR Fimbrial protein CEJ55_03465 ENOG4108VCD Chaperone CEJ55_03470 ENOG4105CW0 outer membrane usher protein CEJ55_03475 ENOG4105MHR Fimbrial protein CEJ55_03480 ENOG4106UCC Fimbrial protein CEJ55_03485 ENOG4105DIJ Phosphoethanolamine transferase CEJ55_03505 ENOG4105DEF Extracellular solute-binding protein, family 5 CEJ55_03515 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEJ55_03520 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEJ55_03525 ENOG4105C3U ABC transporter CEJ55_03530 ENOG4108JQ7 (ABC) transporter CEJ55_03535 ENOG4105C44 Serine transporter CEJ55_03575 ENOG4105D1V cellulose synthase operon protein YhjU CEJ55_03580 ENOG4105WQA Cellulose biosynthesis protein BcsF CEJ55_03585 ENOG4105U74 cellulose biosynthesis protein BcsE CEJ55_03590 ENOG410661M cytoplasmic protein CEJ55_03600 ENOG4107QZ7 Cellulose synthase catalytic subunit CEJ55_03605 ENOG4107EEX Cellulose synthase regulator protein CEJ55_03610 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CEJ55_03615 ENOG4105EJG cellulose synthase CEJ55_03620 ENOG4105BZU Histidine kinase CEJ55_03640 ENOG4105CS0 peptidase CEJ55_03655 ENOG4105CMB EAL domain-containing protein CEJ55_03660 ENOG41066T0 asmA family CEJ55_03665 ENOG4105CSH Transporter CEJ55_03670 ENOG4107H3J ribonuclease CEJ55_03675 ENOG4105CBN LysR family transcriptional regulator CEJ55_03680 ENOG4106S2D Transcriptional regulator CEJ55_03690 ENOG4105CA0 peroxidase CEJ55_03695 ENOG4105CVK Glutamate decarboxylase CEJ55_03700 ENOG4108NKV transcriptional regulator CEJ55_03705 ENOG4105D3F AraC Family Transcriptional Regulator CEJ55_03715 ENOG4105BZS acriflavin resistance protein CEJ55_03720 ENOG4105C1P efflux transporter, rnd family, mfp subunit CEJ55_03730 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci CEJ55_03735 ENOG4108YK4 Acid-resistance membrane protein CEJ55_03740 ENOG41060V2 Acid-resistance protein CEJ55_03745 ENOG4105XXV Acid-resistance protein CEJ55_03750 ENOG4105KT7 mgtC SapB transporter CEJ55_03765 ENOG4105Y4Z Outer Membrane Lipoprotein CEJ55_03785 ENOG4105K89 arsenate reductase CEJ55_03790 ENOG4107R5R arsenical pump membrane protein CEJ55_03795 ENOG4105KBH arsR family transcriptional regulator CEJ55_03810 ENOG4105DC8 reductase CEJ55_03815 ENOG4105D6S protein involved in catabolism of external DNA CEJ55_03820 ENOG4105DGW oligopeptidase A CEJ55_03830 ENOG4105DUX Transporter CEJ55_03840 ENOG4108M6U Universal stress protein A CEJ55_03850 ENOG4105CJ3 phosphate transporter CEJ55_03855 ENOG4105CBX hi0933 family CEJ55_03860 ENOG4107UNS conserved inner membrane protein CEJ55_03880 ENOG4105D0S secretion protein (HlyD CEJ55_03885 ENOG4105CJ1 ABC, transporter CEJ55_03890 ENOG4105CMI transporter CEJ55_03915 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CEJ55_03920 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEJ55_03925 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEJ55_03930 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CEJ55_03935 ENOG4107YAK holo-(acyl carrier protein) synthase 2 CEJ55_03940 ENOG4105DSF transport protein CEJ55_03945 ENOG4105F9N Major Facilitator Superfamily CEJ55_03950 ENOG4108W1V Lipoprotein CEJ55_03955 ENOG4105EX9 Membrane CEJ55_03970 ENOG4107FS9 Membrane CEJ55_03980 ENOG4105MG3 Membrane CEJ55_03985 ENOG4106H78 methyltransferase CEJ55_03990 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CEJ55_03995 ENOG4105CAK Cell division ATP-binding protein ftsE CEJ55_04000 ENOG4105CRP Part of the ABC transporter FtsEX involved in CEJ55_04005 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEJ55_04010 ENOG4105CP9 extracellular ligand-binding receptor CEJ55_04015 ENOG4105U59 -acetyltransferase CEJ55_04025 ENOG4105CP9 extracellular ligand-binding receptor CEJ55_04030 ENOG4105C32 Amino acid ABC transporter (Permease) CEJ55_04035 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CEJ55_04040 ENOG4105C0Z ABC transporter CEJ55_04045 ENOG4108IV0 ABC, transporter CEJ55_04050 ENOG4105BZ7 extracellular solute-binding protein family 1 CEJ55_04055 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component CEJ55_04060 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component CEJ55_04070 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CEJ55_04075 ENOG4105WC8 Conserved Protein CEJ55_04080 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) CEJ55_04085 ENOG4106FA4 CEJ55_04100 ENOG4105GMB type VI secretion system effector, hcp1 family CEJ55_04105 ENOG4105WCN acetyltransferase CEJ55_04115 ENOG4105D9R oxidoreductase CEJ55_04120 ENOG4105C2I pirin domain protein CEJ55_04125 ENOG4105DIQ Transcriptional regulator CEJ55_04130 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CEJ55_04135 ENOG4105C6Z Gluconate CEJ55_04140 ENOG4105C9U ATP-dependent DNA helicase RecQ CEJ55_04150 ENOG41076UM multiple antibiotic resistance (MarC)-related protein CEJ55_04155 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEJ55_04180 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CEJ55_04210 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CEJ55_04225 ENOG4105E98 transcriptional regulator DeoR family CEJ55_04230 ENOG4105CYB regulatoR CEJ55_04235 ENOG4105E0Y RtcB Protein CEJ55_04250 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CEJ55_04255 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CEJ55_04260 ENOG4105C6Z Gluconate CEJ55_04270 ENOG4105MJ2 Competence protein CEJ55_04295 ENOG4105CE1 Ferrous iron transport protein b CEJ55_04300 ENOG4105XFK Ferrous iron transport protein A CEJ55_04310 ENOG4105BZM domain protein CEJ55_04315 ENOG4108RRZ Transcription elongation factor GreB CEJ55_04325 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEJ55_04330 ENOG4105E0F Histidine kinase CEJ55_04355 ENOG4108MAJ Membrane CEJ55_04365 ENOG4105VEJ Heat shock protein CEJ55_04370 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CEJ55_04375 ENOG4105DQY intracellular growth attenuator CEJ55_04380 ENOG4107RK2 ADP-ribose diphosphatase NudE CEJ55_04385 ENOG4108JQC penicillin-binding protein 1A CEJ55_04390 ENOG4108U1Q Pilus assembly protein CEJ55_04395 ENOG41065NF Fimbrial assembly family protein CEJ55_04400 ENOG4105XPX DNA utilization protein HofO CEJ55_04405 ENOG4105ITY Required for the use of extracellular DNA as a nutrient CEJ55_04410 ENOG4105E4G Type IV pilus CEJ55_04430 ENOG4105EGB membrane protein DamX CEJ55_04435 ENOG4105DFE Dna adenine methylase CEJ55_04440 ENOG4105DJV ribulose-phosphate 3-epimerase CEJ55_04450 ENOG4105C31 Tryptophanyl-tRNA synthetase CEJ55_04455 ENOG4108M21 CEJ55_04460 ENOG4105RMW regulation of transcription, DNA-dependent CEJ55_04465 ENOG4108626 Racemase CEJ55_04470 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) CEJ55_04475 ENOG41080QX K07048 phosphotriesterase-related protein CEJ55_04480 ENOG4105MUZ Protein of unknown function DUF2620 CEJ55_04485 ENOG4106M0N transport system permease protein CEJ55_04490 ENOG4106PKC pyridoxal phosphate binding CEJ55_04495 ENOG4105FDP GntR family transcriptional regulator CEJ55_04500 ENOG4108KPW sugar kinase CEJ55_04505 ENOG4107Y0V Not clear, may be involved in an isomerization step CEJ55_04515 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine CEJ55_04520 ENOG4107QHQ amino acid CEJ55_04525 ENOG4105VYH CEJ55_04535 ENOG4107V9H nitrite transporter CEJ55_04540 ENOG4105WZK nitrite reductase NADPH small subunit CEJ55_04545 ENOG4107QZF nitrite reductase NADPH large subunit CEJ55_04555 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CEJ55_04560 ENOG4106195 uncharacterized protein yhfG CEJ55_04565 ENOG4105MZU cell filamentation protein CEJ55_04570 ENOG4105DDQ anthranilate synthase CEJ55_04575 ENOG4105C8Y Acetylornithine aminotransferase CEJ55_04580 ENOG410613R integral membrane protein, YccS YhfK family CEJ55_04585 ENOG4107RYR Transcriptional regulator, Crp Fnr family CEJ55_04595 ENOG4108UKZ OsmC family CEJ55_04600 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CEJ55_04610 ENOG4105DNZ Alpha Beta Hydrolase CEJ55_04615 ENOG4105C5H ABC transporter CEJ55_04635 ENOG4105VKU nucleicacid-binding protein CEJ55_04640 ENOG4108YZY peptidylprolyl cis-trans isomerase CEJ55_04650 ENOG4108V1T peptidylprolyl cis-trans isomerase CEJ55_04655 ENOG4105WWK YheO domain protein CEJ55_04700 ENOG4105W53 bacterioferritin-associated ferredoxin CEJ55_04705 ENOG4108UQY Iron-storage protein CEJ55_04730 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) CEJ55_04735 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) CEJ55_04745 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CEJ55_04750 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) CEJ55_04755 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CEJ55_04760 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) CEJ55_04770 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal CEJ55_04780 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) CEJ55_04795 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) CEJ55_04805 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) CEJ55_04810 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) CEJ55_04820 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) CEJ55_04825 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CEJ55_04830 ENOG41067V7 50S ribosomal protein L36 CEJ55_04835 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits CEJ55_04845 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) CEJ55_04850 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) CEJ55_04860 ENOG4105VTS DnaJ-like, subfamily C CEJ55_04865 ENOG4105W1Y Transcriptional regulator CEJ55_04870 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CEJ55_04880 ENOG4105C1A potassium transporter peripheral membrane CEJ55_04900 ENOG4105C79 DNA protecting protein DprA CEJ55_04910 ENOG4108WI1 Dna topoisomerase CEJ55_04925 ENOG4105SG3 Protein of unknown function (DUF1488) CEJ55_04930 ENOG4108Z0R Transferase CEJ55_04970 ENOG4105CDA abc transporter atp-binding protein CEJ55_04975 ENOG4105DRP amino acid AbC transporter CEJ55_04980 ENOG4105EZ7 amino acid ABC transporter CEJ55_04995 ENOG4105XCM membrane LIPOPROTEIN CEJ55_05000 ENOG4105BZS acriflavin resistance protein CEJ55_05005 ENOG4105C1P efflux transporter, rnd family, mfp subunit CEJ55_05015 ENOG4108XG4 DNA-binding transcriptional regulator CEJ55_05020 ENOG41061ME transport protein CEJ55_05025 ENOG4105CEC DNA methylase N-4 N-6 CEJ55_05085 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CEJ55_05090 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CEJ55_05100 ENOG4108IA2 Sodium pantothenate symporter CEJ55_05105 ENOG4105RG0 Membrane CEJ55_05110 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CEJ55_05115 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CEJ55_05125 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CEJ55_05130 ENOG41062P1 Diguanylate cyclase phosphodiesterase CEJ55_05145 ENOG4105DFF Rod shape-determining protein mreb CEJ55_05150 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CEJ55_05155 ENOG4105VQ7 Rod shape-determining protein MreD CEJ55_05165 ENOG4105C03 ribonuclease CEJ55_05170 ENOG4105QD6 exported protein CEJ55_05175 ENOG4105D1U peptidase U62 modulator of DNA gyrase CEJ55_05180 ENOG4105CR8 Transcriptional regulator CEJ55_05200 ENOG4105UNR (Barnase) inhibitor CEJ55_05205 ENOG4105RID UPF0379 protein yhcN CEJ55_05220 ENOG4105C0H protease CEJ55_05225 ENOG4105C0H protease CEJ55_05230 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CEJ55_05235 ENOG4105D6Z AFG1 family ATPase CEJ55_05245 ENOG4108UJD 30S ribosomal protein S9 CEJ55_05265 ENOG4107MKT Stringent starvation protein a CEJ55_05270 ENOG4105KB2 stringent starvation protein b CEJ55_05275 ENOG4105CEE C4-dicarboxylate transporter CEJ55_05310 ENOG4108R66 Conserved Protein CEJ55_05320 ENOG4105DFS Conserved Protein CEJ55_05325 ENOG4105BZ8 glutamate synthase CEJ55_05330 ENOG4105CBC glutamate synthase CEJ55_05345 ENOG4105N5T Radical SAM Protein CEJ55_05350 ENOG4105BZU Histidine kinase CEJ55_05355 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CEJ55_05365 ENOG4108NIH transferase activity, transferring phosphorus-containing groups CEJ55_05370 ENOG41080Z8 PHOSPHOCARRIER protein CEJ55_05380 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CEJ55_05385 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CEJ55_05390 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEJ55_05395 ENOG4108IUZ ABC transporter CEJ55_05400 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CEJ55_05405 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CEJ55_05415 ENOG4105C2X Arabinose 5-phosphate isomerase CEJ55_05420 ENOG4105FEU K -dependent Na -Ca exchanger CEJ55_05425 ENOG4105DHJ ABC, transporter CEJ55_05430 ENOG4105CY3 ABC transporter, permease CEJ55_05435 ENOG4107PE3 Mammalian cell entry related domain protein CEJ55_05440 ENOG4105E3I toluene tolerance CEJ55_05445 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CEJ55_05450 ENOG4105VFK BolA family CEJ55_05460 ENOG4105HVQ Regulatory factor of maltose metabolism CEJ55_05465 ENOG4105EAH synthase CEJ55_05480 ENOG4105QYV Membrane CEJ55_05490 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CEJ55_05495 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CEJ55_05500 ENOG4105HBR Rna-binding protein CEJ55_05505 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) CEJ55_05510 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CEJ55_05515 ENOG4105EEI dihydropteroate synthase CEJ55_05535 ENOG4105DIJ Phosphoethanolamine transferase CEJ55_05555 ENOG4105CHV Transcription elongation factor NusA CEJ55_05585 ENOG4105RT1 May be involved in cell division (By similarity) CEJ55_05595 ENOG4105C1J atp-dependent rna helicase CEJ55_05600 ENOG4105CIC tryptophan-specific transport protein CEJ55_05605 ENOG4105DEN Luciferase family CEJ55_05610 ENOG4106RZ4 Peptidase U32 CEJ55_05615 ENOG4105CFP Peptidase U32 CEJ55_05620 ENOG4105XPQ lipid carrier protein CEJ55_05625 ENOG4108YYD acetyltransferase CEJ55_05640 ENOG4107R7Y intracellular protease Pfpi family CEJ55_05645 ENOG4105K4T epimerase CEJ55_05650 ENOG4107S21 permease CEJ55_05655 ENOG4105W4M Transport-associated protein CEJ55_05660 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) CEJ55_05675 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CEJ55_05680 ENOG4105I74 Fimbrial protein CEJ55_05685 ENOG4105CW0 outer membrane usher protein CEJ55_05690 ENOG4108VCD Chaperone CEJ55_05695 ENOG4105Q10 Fimbrial-like protein CEJ55_05700 ENOG4106HBN Galactosamine-6-phosphate isomerase CEJ55_05705 ENOG4105F3R pts system mannose fructose sorbose family iid CEJ55_05710 ENOG4105ETZ PTS System CEJ55_05715 ENOG4108UZY PTS System CEJ55_05725 ENOG4105E70 isomerase CEJ55_05730 ENOG4105CE4 GlcNAc 6-P deacetylase CEJ55_05735 ENOG4108YTN IIa component CEJ55_05740 ENOG4105F3R pts system mannose fructose sorbose family iid CEJ55_05750 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB CEJ55_05765 ENOG4105E98 transcriptional regulator DeoR family CEJ55_05770 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression CEJ55_05775 ENOG4105ZEG Suppressor protein CEJ55_05780 ENOG4105CTX dehydratase CEJ55_05785 ENOG4105DJB Major Facilitator Superfamily CEJ55_05795 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CEJ55_05800 ENOG4105BZW Glycerate kinase CEJ55_05825 ENOG410811B TRANSCRIPTIONal CEJ55_05835 ENOG4105C7B Threonine dehydratase CEJ55_05845 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CEJ55_05850 ENOG4105C6N Formate acetyltransferase CEJ55_05855 ENOG4105KME endoribonuclease L-psp CEJ55_05860 ENOG4105EJQ L-serine dehydratase CEJ55_05865 ENOG4105C44 Serine transporter CEJ55_05875 ENOG4106D80 Uncharacterized protein YhaL CEJ55_05880 ENOG4108CNN domain protein CEJ55_05885 ENOG4105CWB LysR family transcriptional Regulator CEJ55_05895 ENOG4105KAF membrAne CEJ55_05900 ENOG4105KAF membrAne CEJ55_05905 ENOG4105CHF Glutathione S-transferase CEJ55_05910 ENOG4108VBZ doxx family CEJ55_05915 ENOG4105YJD CEJ55_05920 ENOG41090KG Inner membrane protein YqjE CEJ55_05925 ENOG4105NE1 Conserved Protein CEJ55_05930 ENOG4105WAY exported protein CEJ55_05935 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) CEJ55_05940 ENOG4106W5V Membrane CEJ55_05945 ENOG4107YCY Transcriptional regulator CEJ55_05970 ENOG4105DPW Major facilitator superfamily MFS_1 CEJ55_05980 ENOG4105CTX dehydratase CEJ55_05985 ENOG4105P66 Membrane CEJ55_05990 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) CEJ55_05995 ENOG4105DU1 integral membrane protein, terc CEJ55_06000 ENOG4105EE0 oxidoreductase CEJ55_06005 ENOG4108UB4 uncharacterized protein ygjQ CEJ55_06010 ENOG4108VKG metal-dependent hydrolase CEJ55_06020 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase CEJ55_06025 ENOG4108Z3N Transcriptional regulator CEJ55_06030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEJ55_06035 ENOG4107WCA isomerase CEJ55_06040 ENOG4107W6W Conserved Protein CEJ55_06045 ENOG4105E5D amino acid CEJ55_06050 ENOG4105FK9 beta-D-galactosidase beta subunit CEJ55_06055 ENOG4105CNT hydrolase family 2 CEJ55_06060 ENOG4105CQ4 Transcriptional regulator CEJ55_06070 ENOG4108Y51 tRNA-binding protein CEJ55_06085 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CEJ55_06090 ENOG4105NTW Transcriptional regulator CEJ55_06100 ENOG4105Q26 Siderophore-interacting protein CEJ55_06115 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEJ55_06125 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CEJ55_06130 ENOG4105VCC 30S ribosomal protein S21 CEJ55_06140 ENOG4107QPK )-transporter CEJ55_06145 ENOG4107GFK fumarate CEJ55_06150 ENOG4106DSS Tartrate dehydratase subunit alpha CEJ55_06160 ENOG4105EJC lysr family transcriptional regulator CEJ55_06170 ENOG4107ZVW dihydroneopterin aldolase CEJ55_06185 ENOG4106MWK domain protein CEJ55_06195 ENOG4105I7R Adenylate cyclase CEJ55_06215 ENOG4107S78 Band 7 protein CEJ55_06220 ENOG4105PV3 Inner membrane protein yqiJ CEJ55_06230 ENOG4108MY7 Fimbrial CEJ55_06235 ENOG4108TTM chaperone CEJ55_06245 ENOG4105H8W Fimbrial protein CEJ55_06250 ENOG4105W0Z cytoplasmic protein CEJ55_06270 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CEJ55_06275 ENOG4106032 Glutathionylspermidine synthase CEJ55_06290 ENOG4105DFG type I secretion outer membrane protein CEJ55_06295 ENOG41087AY ADP-Ribose pyrophosphatase CEJ55_06300 ENOG4108SX3 cytoplasmic protein CEJ55_06305 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CEJ55_06310 ENOG4105IPS esterase CEJ55_06315 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEJ55_06320 ENOG4105VRH Antibiotic biosynthesis monooxygenase CEJ55_06325 ENOG4105NF4 modulator of drug activity CEJ55_06330 ENOG4107DEU Inner membrane protein YgiZ CEJ55_06335 ENOG4105DHQ Histidine kinase CEJ55_06340 ENOG4105XJC Two component transcriptional regulator (Winged helix family CEJ55_06345 ENOG4105H4F exported protein CEJ55_06350 ENOG4105F4I Transcriptional regulator CEJ55_06360 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEJ55_06365 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CEJ55_06370 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CEJ55_06375 ENOG4105CCT upf0313 protein CEJ55_06385 ENOG4105ZKC Conserved Protein CEJ55_06390 ENOG4105CV8 reductase CEJ55_06395 ENOG4108I6A alcohol dehydrogenase CEJ55_06400 ENOG4105CF7 AraC family transcriptional regulator CEJ55_06405 ENOG4108K81 inner membrane protein YghB CEJ55_06410 ENOG4105C28 cystathionine CEJ55_06420 ENOG4105CWK Biopolymer transport protein, ExbB CEJ55_06425 ENOG4108ZZF transport protein (ExbD) CEJ55_06430 ENOG4105CYX Short-chain dehydrogenase reductase Sdr CEJ55_06440 ENOG4105CPC Aldo Keto reductase CEJ55_06450 ENOG410900S Protein of unknown function (DUF2623) CEJ55_06460 ENOG4105E3S small subunit CEJ55_06465 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CEJ55_06470 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit CEJ55_06475 ENOG4105DPX Hydrogenase, large subunit CEJ55_06480 ENOG4108USZ hydrogenase CEJ55_06485 ENOG4108WGS hydrogenase 2-specific chaperone CEJ55_06490 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CEJ55_06495 ENOG41082MF Hydrogenase assembly chaperone hypC hupF CEJ55_06510 ENOG4105CYM Glutathione S-transferase CEJ55_06515 ENOG4106032 Glutathionylspermidine synthase CEJ55_06525 ENOG4105CJ3 phosphate transporter CEJ55_06530 ENOG4108GH0 ATP-binding protein yghT CEJ55_06535 ENOG4108NDC ATP-binding protein yghS CEJ55_06540 ENOG4106FPV ATP-binding protein YghR CEJ55_06545 ENOG4108S55 polysaccharide biosynthesis protein CEJ55_06555 ENOG4108UUE Transcriptional regulator CEJ55_06560 ENOG4108M8S permease YjgP YjgQ family protein CEJ55_06570 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CEJ55_06575 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CEJ55_06585 ENOG4107RCI amp-dependent synthetase and ligase CEJ55_06600 ENOG4108KWP DNA-binding transcriptional regulator GlcC CEJ55_06605 ENOG4105CQB FAD linked oxidase domain protein CEJ55_06610 ENOG4105EU8 FAD linked oxidase domain protein CEJ55_06615 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CEJ55_06620 ENOG4108ZJF Glcg protein CEJ55_06625 ENOG4107QP3 malate synthase g CEJ55_06630 ENOG4105DAA L-lactate CEJ55_06640 ENOG4105F88 accessory colonization factor AcfD CEJ55_06650 ENOG410765S (LipO)protein CEJ55_06665 ENOG4107QHF type ii secretion system protein e CEJ55_06670 ENOG4105D7Q type ii secretion system CEJ55_06675 ENOG4108VAU general secretion pathway protein G CEJ55_06685 ENOG4105X5Z General secretion pathway protein I CEJ55_06705 ENOG4105U1E general secretion pathway protein M CEJ55_06710 ENOG4105BZU Histidine kinase CEJ55_06730 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles CEJ55_06740 ENOG4106WJE Protein of unknown function (DUF987) CEJ55_06745 ENOG4108YGG dna repair protein CEJ55_06750 ENOG4106549 Antirestriction protein CEJ55_06755 ENOG4106H6R UPF0380 protein CEJ55_06765 ENOG4105F4K antigen 43 CEJ55_06775 ENOG4108P8R CEJ55_06830 ENOG4105D5K Hemolysin activator protein CEJ55_06880 ENOG4105VNT transposase (IS4 family) protein CEJ55_06890 ENOG4108YXQ IS66 Orf2 family protein CEJ55_06900 ENOG4105BZU Histidine kinase CEJ55_06940 ENOG4105E5H Transposase CEJ55_06945 ENOG4108YXQ IS66 Orf2 family protein CEJ55_06965 ENOG4108YXQ IS66 Orf2 family protein CEJ55_07065 ENOG4108SIC Transcriptional regulator CEJ55_07080 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CEJ55_07085 ENOG4108IJ0 Aspartate ammonia-lyase CEJ55_07090 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 CEJ55_07095 ENOG4105DVH amino acid CEJ55_07110 ENOG4108ZVF (LipO)protein CEJ55_07115 ENOG4105MTB Uncharacterized protein YjeJ CEJ55_07120 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CEJ55_07130 ENOG4106HKS Entericidin EcnA/B family CEJ55_07135 ENOG4106BSU Entericidin B CEJ55_07140 ENOG4105KPY Small multidrug resistance protein CEJ55_07145 ENOG4105QNF Outer membrane lipoprotein CEJ55_07150 ENOG41066YJ Beta-lactamase CEJ55_07165 ENOG4105E33 succinate dehydrogenase CEJ55_07170 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CEJ55_07180 ENOG4107SC7 Inner membrane transporter yjeM CEJ55_07185 ENOG4106V5W CEJ55_07190 ENOG4106CG8 Inner membrane protein YjeO CEJ55_07195 ENOG4105EGS Mechanosensitive ion channel CEJ55_07235 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CEJ55_07240 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CEJ55_07245 ENOG4105K8N protein family UPF0079, ATPase CEJ55_07250 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CEJ55_07265 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) CEJ55_07270 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CEJ55_07275 ENOG4107QJR hflk protein CEJ55_07280 ENOG4105EPW hflc protein CEJ55_07300 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CEJ55_07305 ENOG4105C2N RNA methyltransferase TrmH family group 3 CEJ55_07310 ENOG4105FUX Conserved Protein CEJ55_07315 ENOG4108P9J Phage shock protein A CEJ55_07320 ENOG4107VNS Protein of unknown function (DUF2491) CEJ55_07325 ENOG4105Z6B inner membrane protein yjfl CEJ55_07330 ENOG4108KXT Conserved Protein CEJ55_07335 ENOG4106032 Glutathionylspermidine synthase CEJ55_07340 ENOG4105CSU acyl-Coa dehydrogenase CEJ55_07350 ENOG4105S17 UPF0379 protein yjfN CEJ55_07355 ENOG4105WSB biofilm stress and motility protein A CEJ55_07360 ENOG4108MXZ Esterase CEJ55_07375 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CEJ55_07380 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport CEJ55_07405 ENOG4105R3P Inner membrane protein yagU CEJ55_07410 ENOG4105KIT UPF0379 protein yjfY CEJ55_07425 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CEJ55_07450 ENOG4108RS6 transposase CEJ55_07455 ENOG4105D7V transposase CEJ55_07465 ENOG4105FHY Opacity-associated protein A CEJ55_07475 ENOG4108V1T peptidylprolyl cis-trans isomerase CEJ55_07480 ENOG4105C85 amino acid CEJ55_07490 ENOG4105DXC membrane CEJ55_07495 ENOG4105ECR NmrA family CEJ55_07500 ENOG4105KVH Transcriptional regulator CEJ55_07505 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CEJ55_07510 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CEJ55_07515 ENOG4108UUE Transcriptional regulator CEJ55_07520 ENOG41061GZ Protein of unknown function (DUF1107) CEJ55_07525 ENOG4105C37 (CBS) domain CEJ55_07540 ENOG4105CFU surface antigen CEJ55_07545 ENOG4105MA0 exported protein CEJ55_07550 ENOG4108ZHD aig2 family CEJ55_07555 ENOG4105F0N pyrophosphate phospho-hydrolase CEJ55_07560 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator CEJ55_07565 ENOG4105C2J ABC transporter CEJ55_07570 ENOG4107R9N ABC transporter CEJ55_07575 ENOG41062B0 ABC transporter, permease CEJ55_07585 ENOG4105DFU Cell wall formation (By similarity) CEJ55_07595 ENOG4105CMS peptidase U62, modulator of DNA gyrase CEJ55_07605 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CEJ55_07610 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CEJ55_07615 ENOG4105CG3 alpha amylase, catalytic region CEJ55_07620 ENOG4105C5Y PTS System CEJ55_07625 ENOG4105D4X repressor CEJ55_07630 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CEJ55_07640 ENOG4105KME endoribonuclease L-psp CEJ55_07655 ENOG41077AM PyrBI operon attenuator CEJ55_07665 ENOG4108UQ8 endoribonuclease L-psp CEJ55_07670 ENOG4105F6U Short-chain dehydrogenase reductase Sdr CEJ55_07675 ENOG4108XFH Transcriptional regulator CEJ55_07680 ENOG4105XEP YhcH YjgK YiaL family protein CEJ55_07700 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CEJ55_07705 ENOG4108MJ3 acetyltransferase CEJ55_07710 ENOG4108M3P Membrane CEJ55_07715 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CEJ55_07720 ENOG4105MYG DNA polymerase iii, chi subunit CEJ55_07730 ENOG4108M8S permease YjgP YjgQ family protein CEJ55_07735 ENOG4108K5H permease YjgP YjgQ family protein CEJ55_07740 ENOG4105D7A ATP-binding protein CEJ55_07745 ENOG4105DQ4 alcohol dehydrogenase CEJ55_07815 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria CEJ55_07830 ENOG4108W9T type 1 fimbriae regulatory protein CEJ55_07835 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off CEJ55_07845 ENOG4108RQP Major type 1 subunit fimbrin CEJ55_07850 ENOG4108S54 Fimbrial protein CEJ55_07855 ENOG4108NAE Fimbrial chaperone protein CEJ55_07860 ENOG4105CW0 outer membrane usher protein CEJ55_07865 ENOG4108SQA Fimbrial CEJ55_07870 ENOG4108T65 Fimbrial CEJ55_07875 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin CEJ55_07880 ENOG4107EFN gluconate transport system permease 3 CEJ55_07895 ENOG4105DEI Mannitol dehydrogenase CEJ55_07905 ENOG4105C6F GntR Family Transcriptional Regulator CEJ55_07930 ENOG4107YNJ LysR family Transcriptional regulator CEJ55_07935 ENOG4105DYB Isoaspartyl dipeptidase CEJ55_07940 ENOG4108P2H Inner membrane protein YjiG CEJ55_07945 ENOG41074DU domain protein CEJ55_07960 ENOG4105CBP Major Facilitator CEJ55_07975 ENOG4105CIZ coA-substrate-specific enzyme activase CEJ55_07980 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase CEJ55_07985 ENOG4106BRA Membrane CEJ55_07990 ENOG41083G8 Multidrug resistance protein MdtM CEJ55_08005 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEJ55_08010 ENOG4106DIZ Domain of unknown function (DUF1127) CEJ55_08020 ENOG4105CKI cobalamin synthesis protein CEJ55_08025 ENOG4105VCD cytoplasmic protein CEJ55_08030 ENOG4105D22 carbon starvation protein CEJ55_08040 ENOG4107UWN reductase CEJ55_08045 ENOG4105EFA 4-hydroxyphenylacetate CEJ55_08075 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CEJ55_08080 ENOG4105C26 Dehydrogenase CEJ55_08085 ENOG4105ERH Fumarylacetoacetate hydrolase CEJ55_08090 ENOG4108V8F Transcriptional regulator, MarR family CEJ55_08095 ENOG4105C8Q Methyl-accepting chemotaxis CEJ55_08100 ENOG4108I5G Major Facilitator superfamily CEJ55_08105 ENOG410617M Transcriptional regulator CEJ55_08110 ENOG4105CPQ Dehydrogenase CEJ55_08120 ENOG4105RI1 glycoprotein receptor CEJ55_08125 ENOG4106CVF DNA replication protein CEJ55_08135 ENOG4107XM3 UPF0442 protein CEJ55_08140 ENOG4105DWK Membrane CEJ55_08145 ENOG4108N8T regulatoR CEJ55_08150 ENOG4108T94 DNA-binding transcriptional activator BglJ CEJ55_08155 ENOG4108819 ferric iron reductase CEJ55_08160 ENOG4105YBH Protein of unknown function (DUF1435) CEJ55_08185 ENOG4108WPU DNA polymerase III subunit psi CEJ55_08190 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CEJ55_08195 ENOG4105PAD Hydrolase CEJ55_08205 ENOG4105K3G Periplasmic Protein CEJ55_08215 ENOG4108NRW Phospholipase, patatin family CEJ55_08220 ENOG4105EYA deoxyribonuclease CEJ55_08225 ENOG41076CZ activating enzyme CEJ55_08230 ENOG4105G0K glycine radical enzyme YjjI family CEJ55_08260 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) CEJ55_08265 ENOG4105EAC phosphoserine phosphatase CEJ55_08270 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CEJ55_08275 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CEJ55_08280 ENOG4105C5H ABC transporter CEJ55_08290 ENOG4107SC1 transglycosylase CEJ55_08315 ENOG4108RH0 Crea protein CEJ55_08320 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEJ55_08325 ENOG4105EB3 Histidine kinase CEJ55_08330 ENOG4105CT7 inner membrane cred family protein CEJ55_08335 ENOG41065U4 response regulator CEJ55_08340 ENOG410759A CEJ55_08345 ENOG4106FVC RNA methyltransferase CEJ55_08355 ENOG4105CFH Aspartokinase CEJ55_08365 ENOG4105D98 threonine synthase CEJ55_08370 ENOG41062C6 Protein of unknown function (DUF2502) CEJ55_08380 ENOG4105BZG amino acid carrier protein CEJ55_08390 ENOG4108RIR Molybdenum cofactor biosynthesis protein CEJ55_08395 ENOG4106HK8 GPR1 FUN34 yaaH family protein CEJ55_08400 ENOG4108QUJ UPF0174 protein YaaW CEJ55_08420 ENOG4105WI6 cell killing protein encoded within cryptic prophage CEJ55_08430 ENOG41063Z6 transcriptional regulator, lysR family CEJ55_08455 ENOG410647N response to DNA damage stimulus CEJ55_08460 ENOG4105DTN riboflavin biosynthesis protein ribF CEJ55_08475 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CEJ55_08500 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CEJ55_08505 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CEJ55_08515 ENOG4108XNW Transcriptional activatory protein CaiF CEJ55_08525 ENOG4106YT9 Enoyl-CoA hydratase CEJ55_08560 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CEJ55_08565 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein CEJ55_08570 ENOG4105C54 Major Facilitator superfamily CEJ55_08585 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) CEJ55_08610 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) CEJ55_08615 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) CEJ55_08620 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) CEJ55_08625 ENOG4105D3G Pseudouridine synthase CEJ55_08635 ENOG4105CQ2 DNA polymerase CEJ55_08640 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CEJ55_08660 ENOG41063TF transcriptional regulator (AraC CEJ55_08665 ENOG4108KF1 Membrane CEJ55_08675 ENOG4106SMU thiamine transporter membrane protein CEJ55_08680 ENOG4105DP9 ABC transporter CEJ55_08685 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CEJ55_08695 ENOG4105S8Q sugar efflux transporter CEJ55_08710 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CEJ55_08725 ENOG41064T2 transcriptional regulator, lysR family CEJ55_08730 ENOG4105C7K acetolactate synthase CEJ55_08735 ENOG4108ZP8 Acetolactate synthase small subunit CEJ55_08745 ENOG4107B7Y DNA-binding transcriptional regulator FruR CEJ55_08765 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CEJ55_08770 ENOG4105CJN penicillin-binding protein CEJ55_08775 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CEJ55_08780 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CEJ55_08795 ENOG4105CNI cell division protein FtsW CEJ55_08810 ENOG4105CPF Cell wall formation (By similarity) CEJ55_08815 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CEJ55_08820 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CEJ55_08825 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CEJ55_08845 ENOG4105M6F mutator MutT protein CEJ55_08860 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CEJ55_08870 ENOG4105D7Q type ii secretion system CEJ55_08875 ENOG4107QHF type ii secretion system protein e CEJ55_08880 ENOG4108ZUW Major pilin subunit CEJ55_08890 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CEJ55_08895 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CEJ55_08900 ENOG4106A72 regulatory protein AmpE CEJ55_08905 ENOG4105C85 amino acid CEJ55_08910 ENOG41073TP transcriptional regulator CEJ55_08920 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CEJ55_08925 ENOG4107QSN dihydrolipoamide acetyltransferase CEJ55_08930 ENOG4107QN2 dihydrolipoyl dehydrogenase CEJ55_08935 ENOG4108NST exported protein CEJ55_08945 ENOG4107QIJ Aconitate hydratase 2 CEJ55_08965 ENOG4108ZRK uncharacterized protein yacC CEJ55_08970 ENOG4105E3B Multicopper oxidase CEJ55_08975 ENOG4105DZG Dehydrogenase CEJ55_08980 ENOG4108UGV hypoxanthine phosphoribosyltransferase CEJ55_08985 ENOG41077A9 carbonic anhydrase CEJ55_08990 ENOG4105DA5 (ABC) transporter CEJ55_08995 ENOG4105E3A (ABC) transporter CEJ55_09000 ENOG4108YTN IIa component CEJ55_09005 ENOG4107BJW polysaccharide deacetylase CEJ55_09020 ENOG4108A32 Transposase CEJ55_09035 ENOG4105P0Q fimbrial-like protein YadC CEJ55_09040 ENOG4105SN2 fimbrial-like adhesin protein CEJ55_09045 ENOG4105SYG Fimbrial protein CEJ55_09050 ENOG4108XEY fimbrial-like adhesin protein CEJ55_09055 ENOG4105CW0 outer membrane usher protein CEJ55_09060 ENOG4108VEV chaperone CEJ55_09070 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CEJ55_09075 ENOG4105DJ0 Poly(A) Polymerase CEJ55_09080 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) CEJ55_09085 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CEJ55_09095 ENOG4107XID 2'-5' rna ligase CEJ55_09100 ENOG4105CQ7 ATP-dependent helicase CEJ55_09110 ENOG4105BZ4 penicillin-binding protein CEJ55_09115 ENOG4105E0K tonB-dependent siderophore receptor CEJ55_09120 ENOG4105E0A ABC, transporter CEJ55_09125 ENOG4105J76 Periplasmic binding protein CEJ55_09130 ENOG4105S6R Iron-hydroxamate transporter permease subunit CEJ55_09150 ENOG4105EN6 Membrane CEJ55_09155 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CEJ55_09175 ENOG4105C0H protease CEJ55_09180 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR CEJ55_09200 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CEJ55_09235 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) CEJ55_09240 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CEJ55_09245 ENOG4105KNE Phosphatidate cytidylyltransferase CEJ55_09250 ENOG4105DZP Membrane-associated zinc metalloprotease CEJ55_09260 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) CEJ55_09265 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) CEJ55_09290 ENOG4105C0B DNA polymerase III (alpha subunit) CEJ55_09300 ENOG4105CXN decarboxylase CEJ55_09305 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CEJ55_09310 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) CEJ55_09315 ENOG4105M1T rho-binding antiterminator CEJ55_09325 ENOG4108VWS Yaeq family CEJ55_09330 ENOG4108YZN class I peptide chain release factor CEJ55_09335 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CEJ55_09350 ENOG4108R96 Methyltransferase, YaeB family CEJ55_09355 ENOG4108R8X outer membrane lipoprotein CEJ55_09360 ENOG4105D01 (LipO)protein CEJ55_09365 ENOG4108UMI ABC transporter, permease CEJ55_09370 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CEJ55_09375 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CEJ55_09410 ENOG4105CV8 reductase CEJ55_09415 ENOG4105HEI LysR family (Transcriptional regulator CEJ55_09425 ENOG4105F2W methyltransferase CEJ55_09430 ENOG4105E9H Lytic Murein transglycosylase CEJ55_09440 ENOG4105D1A Methyltransferase CEJ55_09450 ENOG4107RZZ dna polymerase iii epsilon subunit CEJ55_09460 ENOG410600K aminopeptidase CEJ55_09475 ENOG4105GMB type VI secretion system effector, hcp1 family CEJ55_09500 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEJ55_09555 ENOG4108WC9 type VI secretion system effector, hcp1 family CEJ55_09565 ENOG4105CS6 Rhs element vgr protein CEJ55_09575 ENOG410600T transposase CEJ55_09615 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CEJ55_09620 ENOG4108WN0 inhibitor of vertebrate lysozyme CEJ55_09625 ENOG4107QPN acyl-Coa dehydrogenase CEJ55_09635 ENOG4105E7A Glutamine amidotransferase CEJ55_09640 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CEJ55_09645 ENOG4105VXN addiction module toxin, RelE StbE family CEJ55_09655 ENOG4108YS0 lipoprotein YafL CEJ55_09675 ENOG4105D00 flagellar biosynthetic protein flhB CEJ55_09680 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CEJ55_09685 ENOG4105VS8 Flagellar biosynthetic protein fliq CEJ55_09690 ENOG4105CN7 Flagellar biosynthetic protein FliP CEJ55_09695 ENOG4105DD5 Flagellar motor switch protein CEJ55_09705 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEJ55_09715 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CEJ55_09720 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEJ55_09730 ENOG4108JIR Flagellum-specific ATP synthase CEJ55_09740 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase CEJ55_09780 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CEJ55_09785 ENOG4108ZC9 flagellar basal-body rod protein flgc CEJ55_09795 ENOG4105BZE flagellar hook protein, FlgE CEJ55_09800 ENOG4108KPB Flagellar basal-body rod protein FlgF CEJ55_09805 ENOG4105CGA flagellar basal-body rod protein FlgG CEJ55_09820 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CEJ55_09830 ENOG4105DTJ flagellar hook-associated protein CEJ55_09845 ENOG4105I03 Flagellin CEJ55_09855 ENOG410804A Flagellar hook-associated 2 domain-containing protein CEJ55_09885 ENOG4107RD7 Flagellar Motor Protein, MotA CEJ55_09895 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CEJ55_09900 ENOG4108HYG acetyltransferase CEJ55_09915 ENOG4108S2Y peptide Chain Release factor CEJ55_09920 ENOG4105CIN aminoacyl-histidine dipeptidase CEJ55_09940 ENOG4105FCK Membrane CEJ55_09965 ENOG4107XAN XdhC and CoxI family CEJ55_09970 ENOG4105C7W Xanthine dehydrogenase CEJ55_09975 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding CEJ55_09980 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit CEJ55_09990 ENOG4105R3P Inner membrane protein yagU CEJ55_10000 ENOG4105PI0 Ferredoxin CEJ55_10005 ENOG4108UD7 cell wall organization CEJ55_10010 ENOG4106PYX Receptor CEJ55_10015 ENOG4108N3D putative enzyme CEJ55_10075 ENOG4108KBJ Inner membrane protein YkgB CEJ55_10080 ENOG41066GK UPF0379 protein ykgI CEJ55_10085 ENOG4107QN2 dihydrolipoyl dehydrogenase CEJ55_10090 ENOG4108K01 transcriptional regulator CEJ55_10095 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CEJ55_10100 ENOG4107QR9 Iron-sulfur cluster binding protein CEJ55_10105 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) CEJ55_10145 ENOG4105C94 Transporter CEJ55_10155 ENOG4105BZU Histidine kinase CEJ55_10160 ENOG4108NUU Transcriptional regulator CEJ55_10165 ENOG4105SZ2 membrAne CEJ55_10175 ENOG4107SNB ankyrin repeat protein YahD CEJ55_10180 ENOG4105N16 Protein of unknown function (DUF2877) CEJ55_10185 ENOG4107R1Q Membrane protein FdrA CEJ55_10190 ENOG4107REC cytoplasmic protein CEJ55_10195 ENOG4105C5B carbamate kinase CEJ55_10200 ENOG4105DZC cytosine deaminase CEJ55_10210 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEJ55_10215 ENOG4105C2J ABC transporter CEJ55_10220 ENOG4105CNN ABC, transporter CEJ55_10225 ENOG4105CNN ABC, transporter CEJ55_10230 ENOG4105DQ4 alcohol dehydrogenase CEJ55_10245 ENOG4105E82 cytochrome subunit of dehydrogenase CEJ55_10250 ENOG4105TDT uncharacterized protein yahO CEJ55_10255 ENOG4108JU7 Transcriptional regulator CEJ55_10260 ENOG4105CR4 methylisocitrate lyase CEJ55_10265 ENOG4105BZN citrate synthase CEJ55_10270 ENOG4105DXD 2-methylcitrate dehydratase CEJ55_10275 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CEJ55_10280 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin CEJ55_10285 ENOG4105DZC cytosine deaminase CEJ55_10290 ENOG4105DND Transcriptional regulator CEJ55_10295 ENOG4107B2H carbonic anhydrase CEJ55_10305 ENOG4105DJ2 Major Facilitator Superfamily CEJ55_10310 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CEJ55_10325 ENOG4105ETE Transcriptional regulator (LacI family CEJ55_10330 ENOG4108K2P TRANSCRIPTIONal CEJ55_10365 ENOG4108SC4 )-transporter CEJ55_10370 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CEJ55_10390 ENOG4105SRB Uncharacterized protein yaiO CEJ55_10400 ENOG4108PBI Polysaccharide metabolism CEJ55_10405 ENOG4107W19 lmbE family CEJ55_10415 ENOG4106FTQ Taurine ABC transporter, periplasmic CEJ55_10420 ENOG4108IY8 ABC, transporter CEJ55_10425 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CEJ55_10430 ENOG4105E2B Taurine dioxygenase CEJ55_10435 ENOG4105D52 delta-aminolevulinic acid dehydratase CEJ55_10450 ENOG4108PNB DNA-binding transcriptional regulator CEJ55_10455 ENOG4107R6D beta-lactam binding protein AmpH CEJ55_10465 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 CEJ55_10470 ENOG4107QS8 (LipO)protein CEJ55_10475 ENOG4105FR5 inner membrane protein YaiY CEJ55_10480 ENOG4105UNH Membrane CEJ55_10485 ENOG4105CPF Cell wall formation (By similarity) CEJ55_10500 ENOG4105G6Z alkaline phosphatase CEJ55_10505 ENOG4105VIF phosphate starvation-inducible protein CEJ55_10510 ENOG4105BZU Histidine kinase CEJ55_10515 ENOG4105II7 pyrroline-5-carboxylate reductase CEJ55_10530 ENOG4105SS3 CEJ55_10540 ENOG4105HBA AroM protein CEJ55_10565 ENOG4105DKQ ROK family CEJ55_10570 ENOG4105F27 Major Facilitator CEJ55_10575 ENOG4105EYH Exonuclease CEJ55_10580 ENOG4107RH8 nuclease SbcCD subunit D CEJ55_10585 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEJ55_10590 ENOG4105BZU Histidine kinase CEJ55_10595 ENOG4105CWM branched-chain amino acid transport system II carrier protein CEJ55_10600 ENOG4105C85 amino acid CEJ55_10605 ENOG4107R28 alpha amylase, catalytic region CEJ55_10625 ENOG4105VIE preprotein translocase, subunit YajC CEJ55_10630 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CEJ55_10635 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CEJ55_10640 ENOG4105N1F Hnh endonuclease CEJ55_10645 ENOG4105DRB nucleoside-specific channel-forming protein CEJ55_10650 ENOG4108KIC (LipO)protein CEJ55_10660 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CEJ55_10665 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) CEJ55_10675 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CEJ55_10680 ENOG4108ZAI phosphatidylglycerophosphatase a CEJ55_10685 ENOG4105CPC Aldo Keto reductase CEJ55_10695 ENOG4105CTB Polyprenyl synthetase CEJ55_10710 ENOG4107S0N DJ-1 family CEJ55_10715 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CEJ55_10725 ENOG4107RDB Major Facilitator CEJ55_10750 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CEJ55_10755 ENOG4105CCU oxidase (Subunit III) CEJ55_10760 ENOG4105BZ9 Cytochrome C oxidase, subunit I CEJ55_10765 ENOG4105E2S oxidase) subunit II CEJ55_10770 ENOG4105EYM Major Facilitator superfamily CEJ55_10775 ENOG4105IEY (LipO)protein CEJ55_10780 ENOG4105M85 Bola protein CEJ55_10805 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CEJ55_10810 ENOG4105K70 DNA-binding protein CEJ55_10815 ENOG4105EIN peptidylprolyl cis-trans isomerase CEJ55_10820 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CEJ55_10825 ENOG4108TGP Thioesterase superfamily protein CEJ55_10835 ENOG4108NFA extracellular solute-binding protein CEJ55_10845 ENOG4108XM1 transcriptional regulator AsnC family CEJ55_10850 ENOG4105BZ1 (ABC) transporter CEJ55_10855 ENOG4105BZ1 (ABC) transporter CEJ55_10860 ENOG4108YZA Nitrogen regulatory protein pii CEJ55_10865 ENOG4105BZU Histidine kinase CEJ55_10870 ENOG4105C29 acyl-CoA thioesterase CEJ55_10875 ENOG4108MNP Glycoprotein polysaccharide metabolism CEJ55_10880 ENOG41080UX Methyltransferase CEJ55_10890 ENOG4105KCV RNA signal recognition particle 4.5S RNA CEJ55_10895 ENOG41066DG (EAL) domain protein CEJ55_10900 ENOG4105GSJ Inner membrane protein ylaC CEJ55_10905 ENOG4108UW5 maltose o-acetyltransferase CEJ55_10910 ENOG4105KF5 hemolysin expression-modulating protein CEJ55_10915 ENOG4108UKR Biofilm formation regulator YbaJ CEJ55_10920 ENOG4105BZS acriflavin resistance protein CEJ55_10925 ENOG4105C1P efflux transporter, rnd family, mfp subunit CEJ55_10930 ENOG4108IG5 Transcriptional regulator CEJ55_10940 ENOG4105EGS Mechanosensitive ion channel CEJ55_10945 ENOG4106428 Protein of unknown function (DUF2496) CEJ55_10950 ENOG4108URS primosomal replication protein n'' CEJ55_10955 ENOG4105WD1 Membrane CEJ55_10970 ENOG4107QMP dna polymerase iii subunits gamma and tau CEJ55_11010 ENOG4107RE1 Inosine-guanosine kinase CEJ55_11015 ENOG4105CKD glutathione-regulated potassium-efflux system protein CEJ55_11020 ENOG4105EU0 Major facilitator Superfamily CEJ55_11030 ENOG4105CGH 5'-nucleotidase CEJ55_11035 ENOG4108Z66 YbaK ebsC protein CEJ55_11045 ENOG4105MBR gumn family CEJ55_11050 ENOG41081XE plasmid maintenance system antidote protein, xre family CEJ55_11055 ENOG4105C59 p-type ATPase CEJ55_11060 ENOG4105CSV Glutaminase CEJ55_11065 ENOG4107RY6 amino acid CEJ55_11075 ENOG4108Z6Z Transcriptional regulator CEJ55_11080 ENOG4105G5H Membrane CEJ55_11085 ENOG4107QX8 SPFH domain, Band 7 family protein CEJ55_11090 ENOG41083J0 (ABC) transporter CEJ55_11095 ENOG4105C4B ABC transporter, permease CEJ55_11100 ENOG4107QR8 Thioredoxin CEJ55_11105 ENOG4105E1F short-chain dehydrogenase reductase CEJ55_11110 ENOG4108UJV acyl-CoA thioesterase i CEJ55_11115 ENOG4108I0Y (ABC) transporter CEJ55_11120 ENOG4105CV6 ABC transporter, permease CEJ55_11125 ENOG4105CNA YD repeat protein CEJ55_11155 ENOG4107653 Transcriptional regulator CEJ55_11160 ENOG4108Z2U ureidoglycolate hydrolase CEJ55_11165 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region CEJ55_11170 ENOG41060W2 glyoxylate carboligase CEJ55_11175 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CEJ55_11180 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CEJ55_11185 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CEJ55_11195 ENOG4105DTE Xanthine uracil vitamin C permease CEJ55_11200 ENOG4105BZW Glycerate kinase CEJ55_11205 ENOG4105S0E allantoin catabolism protein CEJ55_11210 ENOG4105CE7 Amidase, hydantoinase carbamoylase family CEJ55_11215 ENOG4105DG4 malate L-lactate dehydrogenase CEJ55_11220 ENOG4107R1Q Membrane protein FdrA CEJ55_11225 ENOG4107REC cytoplasmic protein CEJ55_11230 ENOG4105G5A Protein of unknown function (DUF2877) CEJ55_11235 ENOG4105C5B carbamate kinase CEJ55_11240 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CEJ55_11245 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CEJ55_11260 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CEJ55_11270 ENOG4105S2T inner membrane protein YbcI CEJ55_11275 ENOG4105WQ3 Rna-binding protein CEJ55_11290 ENOG4108AF8 Chaperone CEJ55_11295 ENOG4105CW0 outer membrane usher protein CEJ55_11305 ENOG4108ZI2 Fimbrial protein CEJ55_11310 ENOG4108Q9V regulatoR CEJ55_11335 ENOG4105QUW CEJ55_11340 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit CEJ55_11345 ENOG410802X bacteriophage n4 adsorption protein b CEJ55_11350 ENOG410600T transposase CEJ55_11375 ENOG4105CNA YD repeat protein CEJ55_11385 ENOG4105CS6 Rhs element vgr protein CEJ55_11395 ENOG4105GR3 Histidine kinase CEJ55_11400 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEJ55_11410 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CEJ55_11415 ENOG410624V efflux system protein CEJ55_11420 ENOG4105EP1 Efflux transporter rnd family, mfp subunit CEJ55_11425 ENOG4108IJF Heavy metal efflux pump, CzcA CEJ55_11430 ENOG4105C85 amino acid CEJ55_11435 ENOG4105CUY Mechanosensitive ion channel CEJ55_11440 ENOG4108RCM Nitroreductase CEJ55_11445 ENOG4105MSB protein, conserved in bacteria CEJ55_11450 ENOG4105WQ6 Membrane CEJ55_11470 ENOG4107635 Hok Gef family protein CEJ55_11475 ENOG4107635 Hok Gef family protein CEJ55_11480 ENOG4108TSE Transferase CEJ55_11485 ENOG4107RNH Outer membrane receptor FepA CEJ55_11495 ENOG4105E93 esterase CEJ55_11500 ENOG41085A6 mbth domain-containing protein CEJ55_11505 ENOG4105C0W non-ribosomal peptide synthetase CEJ55_11510 ENOG4108QY5 Ferric enterobactin transport protein CEJ55_11515 ENOG4105E0A ABC, transporter CEJ55_11520 ENOG4105TVJ transport system, permease CEJ55_11525 ENOG4105DQ5 transport system permease protein CEJ55_11535 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CEJ55_11540 ENOG4105E4F Isochorismate synthase CEJ55_11545 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CEJ55_11550 ENOG4105WQI isochorismatase CEJ55_11555 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase CEJ55_11560 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) CEJ55_11565 ENOG4105D22 carbon starvation protein CEJ55_11570 ENOG4105VCD cytoplasmic protein CEJ55_11575 ENOG4107SCQ Iron-containing alcohol dehydrogenase CEJ55_11580 ENOG4105CHM Aminotransferase CEJ55_11585 ENOG4105GTN ParB Domain Protein Nuclease CEJ55_11590 ENOG4105BZV Phosphoadenosine phosphosulfate reductase CEJ55_11595 ENOG4105DQS Transcriptional regulator CEJ55_11600 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase CEJ55_11605 ENOG4105D3R alkyl hydroperoxide reductase CEJ55_11610 ENOG4108JU3 Alkyl hydroperoxide reductase CEJ55_11615 ENOG4108U51 Universal stress protein CEJ55_11620 ENOG4105E2A Dehydrogenase CEJ55_11630 ENOG4105NXH GreA GreB family elongation factor CEJ55_11640 ENOG4105KTS ribonuclease CEJ55_11645 ENOG4107QPK )-transporter CEJ55_11660 ENOG4105CHY citrate lyase, alpha CEJ55_11665 ENOG4105CI0 Citrate lyase CEJ55_11675 ENOG4105DUA (citrate (pro-3S)-lyase ligase CEJ55_11680 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CEJ55_11685 ENOG4106YYS transcriptional regulatory protein CEJ55_11690 ENOG4105CEE C4-dicarboxylate transporter CEJ55_11700 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) CEJ55_11705 ENOG4105VEQ Cold shock protein CEJ55_11715 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CEJ55_11720 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) CEJ55_11735 ENOG41064T2 transcriptional regulator, lysR family CEJ55_11755 ENOG4105DZ1 carboxypeptidase CEJ55_11760 ENOG4105K6T rare lipoprotein A CEJ55_11765 ENOG4105CNI cell division protein FtsW CEJ55_11770 ENOG4105CJN penicillin-binding protein CEJ55_11780 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CEJ55_11785 ENOG4108TGR phosphatase CEJ55_11795 ENOG4105DJF DNA polymerase III, delta' subunit CEJ55_11810 ENOG4107PAI alpha helical protein CEJ55_11815 ENOG4105EUU Sel1 domain protein repeat-containing protein CEJ55_11820 ENOG41069CF Protein of unknown function (DUF1266) CEJ55_11825 ENOG4105QFC Hsc56 co-chaperone of HscC CEJ55_11830 ENOG4107JFD Sel1 repeat CEJ55_11835 ENOG41069CF Protein of unknown function (DUF1266) CEJ55_11840 ENOG4105QFC Hsc56 co-chaperone of HscC CEJ55_11845 ENOG4105F7F Chaperone CEJ55_11855 ENOG4105CDA abc transporter atp-binding protein CEJ55_11860 ENOG4105DRP amino acid AbC transporter CEJ55_11865 ENOG4105EAD ABC transporter CEJ55_11870 ENOG4107RP9 extracellular solute-binding protein, family 3 CEJ55_11885 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CEJ55_11890 ENOG4108JU5 Magnesium and cobalt efflux protein CEJ55_11900 ENOG4105C9A Phoh family CEJ55_11910 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CEJ55_11955 ENOG4105CAQ asparagine synthetase CEJ55_11965 ENOG4105D4U had-superfamily hydrolase, subfamily iia CEJ55_11970 ENOG4105E2R ROK family CEJ55_11975 ENOG4105CE4 GlcNAc 6-P deacetylase CEJ55_11985 ENOG4105CI1 PTS System CEJ55_12005 ENOG4105GX6 (LipO)protein CEJ55_12010 ENOG41090R7 Ferric uptake CEJ55_12020 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CEJ55_12025 ENOG4105NNH LexA regulated protein CEJ55_12030 ENOG4105EV9 Alpha Beta Hydrolase CEJ55_12035 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) CEJ55_12040 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CEJ55_12045 ENOG4105D5Q Arginine ornithine antiporter CEJ55_12050 ENOG4105CXN decarboxylase CEJ55_12060 ENOG4105EEX Two component transcriptional regulator (Winged helix family CEJ55_12065 ENOG4105C08 Histidine kinase CEJ55_12090 ENOG4105XIQ Protein of unknown function (DUF2517) CEJ55_12095 ENOG4105CNA YD repeat protein CEJ55_12100 ENOG41079JQ Membrane CEJ55_12110 ENOG4106R09 CEJ55_12125 ENOG4107SEY Conserved Protein CEJ55_12130 ENOG4105CVP deoxyribo-dipyrimidine photolyase CEJ55_12135 ENOG4105DUX Transporter CEJ55_12140 ENOG4107QNR UPF0135 protein CEJ55_12145 ENOG4105P4J Allophanate hydrolase, subunit 1 CEJ55_12150 ENOG4107R7A Allophanate hydrolase subunit 2 CEJ55_12165 ENOG4108KK1 membrane protein AbrB duplication CEJ55_12170 ENOG4108MY7 Fimbrial CEJ55_12175 ENOG4108TTM chaperone CEJ55_12180 ENOG4106PG1 outer membrane usher protein CEJ55_12185 ENOG4106UBK fimbrial-like adhesin protein CEJ55_12190 ENOG4105BZN citrate synthase CEJ55_12205 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CEJ55_12210 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CEJ55_12215 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CEJ55_12220 ENOG4105E33 succinate dehydrogenase CEJ55_12225 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CEJ55_12230 ENOG4105C7S Dehydrogenase CEJ55_12240 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CEJ55_12245 ENOG4105FDP GntR family transcriptional regulator CEJ55_12250 ENOG4105DM4 PTS System CEJ55_12255 ENOG4105C8I hydrolase, family 38 CEJ55_12265 ENOG4105C4M (Ubiquinol oxidase) subunit I CEJ55_12270 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CEJ55_12280 ENOG4105KJB cyd operon protein YbgE CEJ55_12285 ENOG4107YD3 Thioesterase CEJ55_12290 ENOG4105E02 MotA TolQ exbB proton channel CEJ55_12295 ENOG4105M8F Biopolymer transport protein exbD tolR CEJ55_12300 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CEJ55_12310 ENOG4105KCK Peptidoglycan-associated lipoprotein CEJ55_12315 ENOG4105UFD tol-pal system protein YbgF CEJ55_12365 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CEJ55_12370 ENOG4105PGM cation diffusion facilitator family transporter CEJ55_12375 ENOG4105JND homeobox protein CEJ55_12385 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEJ55_12395 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CEJ55_12405 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CEJ55_12410 ENOG4105CMR udp-glucose 4-epimerase CEJ55_12415 ENOG4105DKW ABC transporter CEJ55_12420 ENOG4105F4R Transcriptional regulator mode CEJ55_12425 ENOG410680R Protein of unknown function (DUF2592) CEJ55_12435 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CEJ55_12440 ENOG4105E0C molybdate abc transporter CEJ55_12450 ENOG4108K4B hydrolase CEJ55_12460 ENOG4105F04 LysR family Transcriptional regulator CEJ55_12465 ENOG4105C7F AcnD-accessory protein PrpF CEJ55_12470 ENOG4107QPK )-transporter CEJ55_12475 ENOG4107QM5 aconitate hydratase CEJ55_12480 ENOG4105NBR Pectinesterase CEJ55_12490 ENOG4108V1U phospholipid-binding protein CEJ55_12495 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CEJ55_12510 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CEJ55_12515 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CEJ55_12525 ENOG4105CHW UPF0052 protein CEJ55_12535 ENOG4108RIR Molybdenum cofactor biosynthesis protein CEJ55_12545 ENOG4105M00 molybdopterin converting factor, subunit 1 CEJ55_12550 ENOG4108ZAF Molybdopterin CEJ55_12555 ENOG4105HFZ Membrane CEJ55_12565 ENOG410733J conserved inner membrane protein CEJ55_12570 ENOG4107UXM Membrane CEJ55_12575 ENOG4105DZQ phospholipase D Transphosphatidylase CEJ55_12580 ENOG4105X23 Endonuclease Exonuclease phosphatase CEJ55_12585 ENOG4105I9U inner membrane protein ybhQ CEJ55_12590 ENOG4107QWP ABC-2 type transporter CEJ55_12595 ENOG4107QWP ABC-2 type transporter CEJ55_12600 ENOG4105CJ1 ABC, transporter CEJ55_12610 ENOG4107MVR Transcriptional regulator CEJ55_12615 ENOG4105C1J atp-dependent rna helicase CEJ55_12630 ENOG4108UV1 cellular component movement CEJ55_12640 ENOG4105DVT helicase CEJ55_12645 ENOG4108MTB glycosyl transferase family CEJ55_12650 ENOG4105DG4 malate L-lactate dehydrogenase CEJ55_12655 ENOG4105VR4 UPF0379 protein ybiJ CEJ55_12660 ENOG4105KSC Transcriptional regulator, TraR DksA family CEJ55_12670 ENOG4108IU3 tonb-dependent siderophore receptor CEJ55_12675 ENOG4105ZY9 UPF0379 protein ybiM CEJ55_12685 ENOG4105D8X mechanosensitive ion channel CEJ55_12690 ENOG4105CDA abc transporter atp-binding protein CEJ55_12695 ENOG4105E5Q amino acid AbC transporter CEJ55_12700 ENOG4107R0W ABC transporter CEJ55_12725 ENOG4107AQZ Membrane CEJ55_12730 ENOG4108T1M outer membrane protein x CEJ55_12735 ENOG4108I6E Sulfatase CEJ55_12745 ENOG4105KST dependent repressor CEJ55_12750 ENOG4105F4P )-transporter CEJ55_12755 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CEJ55_12760 ENOG4105C5H ABC transporter CEJ55_12775 ENOG41072TH Protein of unknown function (DUF1479) CEJ55_12780 ENOG4108HCJ Hydrolase CEJ55_12785 ENOG4105C6N Formate acetyltransferase CEJ55_12795 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEJ55_12800 ENOG4105D06 uba thif-type nad fad binding protein CEJ55_12805 ENOG4105CVM Molybdenum cofactor synthesis domain protein CEJ55_12810 ENOG4105D44 asparaginase CEJ55_12830 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEJ55_12835 ENOG4105BZU Histidine kinase CEJ55_12840 ENOG41064RH membrane protein YliF CEJ55_12850 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway CEJ55_12855 ENOG4105D8V Glucose sorbosone dehydrogenase CEJ55_12860 ENOG4108TGY Glutathione S-transferase CEJ55_12865 ENOG4105DZ1 carboxypeptidase CEJ55_12870 ENOG4107FB0 transcriptional regulator DeoR family CEJ55_12875 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CEJ55_12880 ENOG4107QF7 multi-drug CEJ55_12890 ENOG4108HCJ Hydrolase CEJ55_12895 ENOG4106UW1 Major Facilitator superfamily CEJ55_12900 ENOG4108RFG Tetr family transcriptional regulator CEJ55_12910 ENOG4105GWF inner membrane protein YbjM CEJ55_12915 ENOG41090BQ Glutaredoxin CEJ55_12920 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CEJ55_12925 ENOG4108DBC nitroreductase CEJ55_12935 ENOG4108RMJ sensory transduction regulator CEJ55_12945 ENOG4107RUE extracellular solute-binding protein family 1 CEJ55_12950 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEJ55_12955 ENOG4105F38 ABC transporter, permease CEJ55_12960 ENOG4105D38 putrescine abc transporter CEJ55_12965 ENOG4105RBQ inner membrane protein ybjO CEJ55_12975 ENOG4106TNF Periplasmic binding protein CEJ55_12980 ENOG4105DMR ABC, transporter CEJ55_12985 ENOG4105GBT ABC transporter CEJ55_12990 ENOG4106PMH Extracellular solute-binding protein family 3 CEJ55_12995 ENOG4105E5Z arginine transporter ATP-binding subunit CEJ55_13000 ENOG41064MM (LipO)protein CEJ55_13010 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CEJ55_13015 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CEJ55_13020 ENOG4105CGD Nad-dependent epimerase dehydratase CEJ55_13025 ENOG4105C5W Aldolase CEJ55_13030 ENOG4105C7K acetolactate synthase CEJ55_13035 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEJ55_13045 ENOG4105DWU Membrane CEJ55_13055 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CEJ55_13060 ENOG4105CPB ATP-dependent endonuclease of the OLD family CEJ55_13065 ENOG4108MJ5 VirK protein CEJ55_13070 ENOG4105DJY efflux transporter, rnd family, mfp subunit CEJ55_13075 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CEJ55_13080 ENOG4105VEQ Cold shock protein CEJ55_13090 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEJ55_13100 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CEJ55_13115 ENOG4108JJ8 (ABC) transporter CEJ55_13120 ENOG4108JJ9 ABC, transporter CEJ55_13125 ENOG4105C3M thioredoxin reductase CEJ55_13135 ENOG4105EW9 transcriptional regulator AsnC family CEJ55_13140 ENOG4105CNU cell division protein FtsK CEJ55_13150 ENOG4105D1H recombination factor protein RarA CEJ55_13160 ENOG4107QY8 reductase CEJ55_13165 ENOG4105QAX Iron-sulfur CEJ55_13170 ENOG4107KGK dmso reductase anchor subunit CEJ55_13175 ENOG4105CHJ isochorismatase hydrolase CEJ55_13185 ENOG4105E5D amino acid CEJ55_13190 ENOG410642W LysR family Transcriptional regulator CEJ55_13195 ENOG4108X0B nad(p)h dehydrogenase (quinone) CEJ55_13200 ENOG4105F1A Pyruvate formate-lyase CEJ55_13205 ENOG4105C6N Formate acetyltransferase CEJ55_13210 ENOG4105TMB Formate nitrite transporter CEJ55_13215 ENOG4105DDY UPF0142 protein ycaO CEJ55_13220 ENOG4107VMU Membrane CEJ55_13235 ENOG4108K0D peptidase, M48 CEJ55_13245 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CEJ55_13255 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CEJ55_13260 ENOG4105BZ1 (ABC) transporter CEJ55_13270 ENOG4105T0Z Conserved Protein CEJ55_13285 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CEJ55_13290 ENOG4107S90 membrAne CEJ55_13300 ENOG4106371 Methyltransferase CEJ55_13310 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CEJ55_13320 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CEJ55_13330 ENOG4105EAQ (twin-arginine translocation) pathway signal CEJ55_13335 ENOG4105C5X domain protein CEJ55_13340 ENOG4105CGF Aromatic amino acid aminotransferase CEJ55_13345 ENOG4105FCK Membrane CEJ55_13360 ENOG4105CD8 aminopeptidase N CEJ55_13370 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CEJ55_13380 ENOG4105GVF (ABC) transporter CEJ55_13385 ENOG4108UZX fmn reductase CEJ55_13395 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon CEJ55_13400 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae CEJ55_13405 ENOG4105CW0 outer membrane usher protein CEJ55_13410 ENOG4108MDY Fimbrial CEJ55_13415 ENOG4105Q7J Fimbrial CEJ55_13420 ENOG4105MX3 Fimbrial CEJ55_13425 ENOG4106PH7 chaperone CEJ55_13435 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CEJ55_13440 ENOG4105QVC MOSC domain-containing protein CEJ55_13450 ENOG4105C5H ABC transporter CEJ55_13455 ENOG4105F1S paraquat-inducible protein a CEJ55_13460 ENOG4105DY2 Paraquat-inducible protein b CEJ55_13465 ENOG4108Q2G (LipO)protein CEJ55_13470 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) CEJ55_13480 ENOG4105DAN ATP-dependent protease CEJ55_13490 ENOG4105UYK outer membrane protein a CEJ55_13505 ENOG4108RZ1 DNA transformation protein CEJ55_13510 ENOG4105EM2 membrane CEJ55_13515 ENOG410901E Membrane CEJ55_13520 ENOG41088T4 Helicase IV CEJ55_13535 ENOG4105K4P CoA-binding domain protein CEJ55_13550 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 CEJ55_13555 ENOG4108Z0T Part of a sulfur-relay system (By similarity) CEJ55_13560 ENOG4108MN8 Membrane CEJ55_13570 ENOG4105E3S small subunit CEJ55_13575 ENOG4105DPX Hydrogenase, large subunit CEJ55_13580 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit CEJ55_13585 ENOG4108USZ hydrogenase CEJ55_13590 ENOG4108VXY Hydrogenase-1 operon protein HyaE CEJ55_13595 ENOG4105MVP hydrogenase-1 operon protein HyaF CEJ55_13600 ENOG4105C4M (Ubiquinol oxidase) subunit I CEJ55_13605 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CEJ55_13615 ENOG4105D6F Phosphatase CEJ55_13620 ENOG4105D75 Capsular exopolysaccharide family CEJ55_13625 ENOG4107ZF2 Phosphatase CEJ55_13630 ENOG4105DAY polysaccharide export protein CEJ55_13635 ENOG4105E3R (LipO)protein CEJ55_13640 ENOG4108W78 Pfam:DUF1017 CEJ55_13645 ENOG4108Y9B (LipO)protein CEJ55_13655 ENOG41060EU Cold shock-like protein CEJ55_13660 ENOG4105VEQ Cold shock protein CEJ55_13675 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation CEJ55_13680 ENOG4105HEE Binding Domain protein CEJ55_13685 ENOG4105BZU Histidine kinase CEJ55_13690 ENOG4108SV3 Tmao reductase system periplasmic protein tort CEJ55_13695 ENOG4106WF9 DNA-binding transcriptional regulator TorR CEJ55_13700 ENOG4105CUW cytochrome C-TYPE protein CEJ55_13730 ENOG4105D6F Phosphatase CEJ55_13735 ENOG4105XH3 CEJ55_13750 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 CEJ55_13755 ENOG4105C2W permease CEJ55_13790 ENOG4108R86 Transcriptional regulator CEJ55_13795 ENOG4105C26 Dehydrogenase CEJ55_13810 ENOG4105CK7 Sodium proline symporter CEJ55_13825 ENOG4105EKT )-iron permease CEJ55_13830 ENOG410650H (LipO)protein CEJ55_13835 ENOG4105DBE peroxidase CEJ55_13845 ENOG4105D5M phosphate starvation-inducible protein CEJ55_13850 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD CEJ55_13855 ENOG4105CND Glycosyl transferase, family 2 CEJ55_13860 ENOG4107BJW polysaccharide deacetylase CEJ55_13865 ENOG4108TUY outer membrane protein PgaA CEJ55_13870 ENOG4105BZU Histidine kinase CEJ55_13885 ENOG4108T85 Membrane CEJ55_13905 ENOG4107XHZ cytoplasmic chaperone TorD family protein CEJ55_13910 ENOG4108UQ5 membrane protein YcdZ CEJ55_13915 ENOG4105P8Q Curli production assembly transport component CsgG CEJ55_13920 ENOG4108WYR Curli production assembly transport component, CsgF CEJ55_13925 ENOG4108XDW curli assembly protein CsgE CEJ55_13930 ENOG41086KC Transcriptional regulator CEJ55_13945 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers CEJ55_13950 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin CEJ55_13965 ENOG4108UVJ appr-1-p processing domain protein CEJ55_13970 ENOG4107RZC phospholipase d CEJ55_13995 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) CEJ55_14000 ENOG4105NAC (LipO)protein CEJ55_14005 ENOG4108W47 Acidic protein msyB CEJ55_14015 ENOG4105D1S lipid A biosynthesis CEJ55_14025 ENOG4108YYC ycei family CEJ55_14030 ENOG4105DS1 cytochrome b561 CEJ55_14035 ENOG4106974 biofilm formation CEJ55_14045 ENOG4105PVA Biofilm formation regulatory protein BssS CEJ55_14050 ENOG4105MEA DNA damage-inducible protein i CEJ55_14060 ENOG4105F3T (LipO)protein CEJ55_14065 ENOG4105E9S glutaredoxin 2 CEJ55_14075 ENOG4105D9U N-acetyltransferase CEJ55_14085 ENOG4105EP9 oxidoreductase CEJ55_14090 ENOG4105CJR Integral membrane protein (MviN CEJ55_14095 ENOG4105QVD Flagella synthesis protein FlgN CEJ55_14100 ENOG4105M9M anti-sigma28 factor FlgM CEJ55_14105 ENOG4105CKS Flagella basal body P-ring formation protein flgA CEJ55_14110 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CEJ55_14115 ENOG4108ZC9 flagellar basal-body rod protein flgc CEJ55_14120 ENOG4105W00 Flagellar hook capping protein CEJ55_14125 ENOG4105BZE flagellar hook protein, FlgE CEJ55_14130 ENOG4108KPB Flagellar basal-body rod protein FlgF CEJ55_14135 ENOG4105CGA flagellar basal-body rod protein FlgG CEJ55_14150 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CEJ55_14155 ENOG4105E1Q flagellar hook-associated protein CEJ55_14160 ENOG4105DTJ flagellar hook-associated protein CEJ55_14165 ENOG4107QQB Ribonuclease E CEJ55_14170 ENOG41071G1 Uncharacterized protein YceQ CEJ55_14175 ENOG4105EI2 Pseudouridine synthase CEJ55_14180 ENOG4108UHJ MAF-like protein CEJ55_14185 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CEJ55_14205 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CEJ55_14210 ENOG4105CHR reductase CEJ55_14215 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CEJ55_14220 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEJ55_14225 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CEJ55_14230 ENOG4105HHA aminodeoxychorismate lyase CEJ55_14240 ENOG4107QRG dna polymerase iii CEJ55_14245 ENOG4105F8V Hydrolase, tatD family CEJ55_14250 ENOG4105CI1 PTS System CEJ55_14255 ENOG4105CNM Receptor CEJ55_14260 ENOG4105K59 histidine triad (HIT) protein CEJ55_14265 ENOG41090DQ Lipoprotein CEJ55_14270 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) CEJ55_14290 ENOG4105CEP NADH dehydrogenase CEJ55_14300 ENOG4107MBR 17 kDa surface antigen CEJ55_14305 ENOG4108IND Tetr family transcriptional regulator CEJ55_14310 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CEJ55_14315 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CEJ55_14320 ENOG4108JA2 transcriptioN-repair coupling factor CEJ55_14325 ENOG4105IQC Inner membrane protein YcfT CEJ55_14330 ENOG4105D60 lipoprotein releasing system transmembrane protein CEJ55_14335 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) CEJ55_14340 ENOG4105D60 lipoprotein releasing system transmembrane protein CEJ55_14350 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CEJ55_14365 ENOG4107RUE extracellular solute-binding protein family 1 CEJ55_14370 ENOG4105D38 putrescine abc transporter CEJ55_14375 ENOG4105F38 ABC transporter, permease CEJ55_14380 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEJ55_14395 ENOG4105EZE Cupin 4 family protein CEJ55_14400 ENOG4105IFJ Histidine kinase CEJ55_14405 ENOG4105XJC Two component transcriptional regulator (Winged helix family CEJ55_14410 ENOG4107QTF adenylosuccinate lyase CEJ55_14430 ENOG4108R99 pseudouridine synthase CEJ55_14435 ENOG4108HMX isocitrate dehydrogenase (NADP) CEJ55_14445 ENOG41064WM Uncharacterized protein YcgX CEJ55_14450 ENOG4108XDN Transcriptional regulator CEJ55_14455 ENOG4105BZU Histidine kinase CEJ55_14460 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component CEJ55_14465 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB CEJ55_14475 ENOG410738I uncharacterized protein ymgC CEJ55_14480 ENOG4105BZU Histidine kinase CEJ55_14505 ENOG410658X CEJ55_14540 ENOG4107QMS site-determining protein CEJ55_14555 ENOG4105S66 prophage protein CEJ55_14560 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium CEJ55_14575 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CEJ55_14590 ENOG4105KT5 UmuD protein CEJ55_14595 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CEJ55_14600 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) CEJ55_14615 ENOG4105ED1 spovr family CEJ55_14625 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEJ55_14635 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CEJ55_14650 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) CEJ55_14675 ENOG4105VDH Dihydroxyacetone kinase CEJ55_14680 ENOG4108UTZ Dihydroxyacetone kinase CEJ55_14685 ENOG4105CMT Dihydroxyacetone kinase CEJ55_14690 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family CEJ55_14695 ENOG4105I1J Autotransporter CEJ55_14710 ENOG4105C3G gtp-binding protein CEJ55_14720 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CEJ55_14725 ENOG4105CHH sulfate transporter CEJ55_14730 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CEJ55_14755 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CEJ55_14760 ENOG4108YY7 Invasion gene expression up-regulator SirB CEJ55_14765 ENOG41063JG Transcriptional regulator CEJ55_14800 ENOG4105EWV Sodium calcium exchanger membrane region CEJ55_14805 ENOG4105WS7 Cation transport regulator CEJ55_14810 ENOG4108NH8 Cation transport protein CEJ55_14815 ENOG41090EX DsrE family CEJ55_14820 ENOG4105ID0 Putative invasin CEJ55_14825 ENOG4105WH1 Two component transcriptional regulator luxr family CEJ55_14830 ENOG4105BZU Histidine kinase CEJ55_14840 ENOG4105DQQ Major facilitator superfamily MFS_1 CEJ55_14845 ENOG4105CRU nitrate reductase, alpha subunit CEJ55_14850 ENOG4108IUE nitrate reductase beta subunit CEJ55_14855 ENOG4105R3A Nitrate reductase CEJ55_14860 ENOG41076YT nitrate reductase, gamma subunit CEJ55_14880 ENOG4105CIY formyltetrahydrofolate deformylase CEJ55_14890 ENOG4105D78 K07001 NTE family protein CEJ55_14895 ENOG4105I93 response regulator CEJ55_14900 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEJ55_14905 ENOG4108SAU DNA-binding protein H-ns CEJ55_14910 ENOG4107104 thymidine kinase CEJ55_14915 ENOG4108EKI Dehydrogenase CEJ55_14920 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CEJ55_14930 ENOG4108J59 Extracellular solute-binding protein, family 5 CEJ55_14940 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEJ55_14945 ENOG4105C3U ABC transporter CEJ55_14950 ENOG4108JQ7 (ABC) transporter CEJ55_14970 ENOG4107SVH Potassium channel protein CEJ55_14975 ENOG4105K9H YciI-like protein CEJ55_14980 ENOG410822N TonB family CEJ55_14985 ENOG4105NAU thioesterase Superfamily protein CEJ55_15010 ENOG4108N8X transition metal ion binding CEJ55_15015 ENOG4108Z9Z response to DNA damage stimulus CEJ55_15035 ENOG4105DK0 Indole-3-glycerol phosphate synthase CEJ55_15040 ENOG4108EFP Anthranilate synthase component II CEJ55_15045 ENOG4105CRQ synthase (Component I) CEJ55_15055 ENOG4105DB7 PHP domain protein CEJ55_15060 ENOG4107RTD sua5 ycio yrdc ywlc family protein CEJ55_15065 ENOG4105FE9 pseudouridine synthase CEJ55_15070 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CEJ55_15075 ENOG4105UBK short-chain dehydrogenase reductase CEJ55_15080 ENOG4105ERU peptidase CEJ55_15085 ENOG4105RKX Protein of unknown function (DUF2498) CEJ55_15095 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CEJ55_15105 ENOG4107R11 Transcriptional regulator CEJ55_15125 ENOG4107QM5 aconitate hydratase CEJ55_15135 ENOG4105EYK Phosphatidylglycerophosphatase B CEJ55_15140 ENOG4105Q4A inner membrane protein yciS CEJ55_15145 ENOG4105CFV Tetratricopeptide repeat protein CEJ55_15155 ENOG4108ZJT translation initiation factor, Sui1 CEJ55_15160 ENOG41061RM osmotically inducible lipoprotein CEJ55_15165 ENOG4105N2W Transcriptional regulator CEJ55_15175 ENOG4105BZU Histidine kinase CEJ55_15190 ENOG4105Q4T oxidoreductase CEJ55_15195 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH CEJ55_15200 ENOG4105WDY DNA (cytosine-5-)-methyltransferase CEJ55_15205 ENOG4108JQ2 peptide transport system atp-binding protein CEJ55_15210 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CEJ55_15215 ENOG4108EU3 peptide transport system, permease CEJ55_15220 ENOG4108I5W peptide transport system, permease protein CEJ55_15225 ENOG4108HIY periplasmic CEJ55_15235 ENOG4105N0E Protein of unknown function (DUF2543) CEJ55_15240 ENOG4105CUB amino acid CEJ55_15245 ENOG4105CFQ glutamine synthetase CEJ55_15250 ENOG4108Z86 Glutamine amidotransferase CEJ55_15255 ENOG4107VRI Transcriptional regulator CEJ55_15260 ENOG4105C26 Dehydrogenase CEJ55_15265 ENOG4105CJP fad dependent oxidoreductase CEJ55_15270 ENOG4108JPW Aminotransferase CEJ55_15275 ENOG4105E51 psp operon transcriptional activator CEJ55_15280 ENOG41087YS Phage shock protein A CEJ55_15285 ENOG4105YYT phage shock protein B CEJ55_15290 ENOG4105FM1 phage shock protein C CEJ55_15295 ENOG4105NNG Peripheral inner membrane phage-shock protein CEJ55_15300 ENOG4105K8Z Phage shock protein CEJ55_15305 ENOG4107QW3 Sucrose phosphorylase CEJ55_15310 ENOG4105WEM extracellular solute-binding protein CEJ55_15315 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component CEJ55_15320 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component CEJ55_15325 ENOG4107RRD Dehydrogenase CEJ55_15330 ENOG4107TYA transient receptor potential locus CEJ55_15335 ENOG4105CK5 oxidoreductase CEJ55_15345 ENOG4107URF beta-phospho-glucomutase CEJ55_15350 ENOG4108IJ9 (ABC) transporter CEJ55_15355 ENOG4107EFV Outer membrane protein G CEJ55_15360 ENOG4105FKQ transcriptional regulator CEJ55_15365 ENOG4105CM6 amino acid regulated cytosolic protein CEJ55_15375 ENOG4108JU8 Transcriptional regulator CEJ55_15380 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CEJ55_15385 ENOG4107S8C mandelate racemase muconate lactonizing CEJ55_15390 ENOG4105KXI murein peptide amidase A CEJ55_15400 ENOG4105ENX hydrolase CEJ55_15405 ENOG4105EQ2 LysR family Transcriptional regulator CEJ55_15410 ENOG4107QSI ABC, transporter CEJ55_15415 ENOG4105D64 Mechanosensitive ion channel CEJ55_15420 ENOG4105S5I Membrane CEJ55_15425 ENOG4105Q9Y Universal stress protein CEJ55_15430 ENOG4105DS0 Transcriptional regulator, Crp Fnr family CEJ55_15435 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEJ55_15440 ENOG4105CFC Transporter CEJ55_15450 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B CEJ55_15455 ENOG4105CH2 amidohydrolase CEJ55_15460 ENOG4106KR7 LysR family Transcriptional regulator CEJ55_15465 ENOG4108DG9 Smr protein MutS2 CEJ55_15470 ENOG4105BZU Histidine kinase CEJ55_15485 ENOG4105C1J atp-dependent rna helicase CEJ55_15490 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) CEJ55_15495 ENOG4107R08 Integrase CEJ55_15500 ENOG4107160 Rac prophage CEJ55_15505 ENOG41070YT Rac prophage CEJ55_15510 ENOG4106YAH restriction alleviation and modification enhancement CEJ55_15515 ENOG4108PNI recT protein CEJ55_15520 ENOG41076J9 exonuclease VIII CEJ55_15530 ENOG4107C82 Rac prophage CEJ55_15560 ENOG410649Z repressor CEJ55_15565 ENOG4105W7J DNA binding CEJ55_15575 ENOG4105ZTP Protein of unknown function (DUF1376) CEJ55_15580 ENOG4105JBR DNA replication protein CEJ55_15615 ENOG4105WI6 cell killing protein encoded within cryptic prophage CEJ55_15630 ENOG4105RWQ Protein of unknown function (DUF1364) CEJ55_15640 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CEJ55_15650 ENOG4105QFS Lysis protein S homolog from lambdoid prophage CEJ55_15655 ENOG4105KUS lysozyme CEJ55_15670 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CEJ55_15680 ENOG4108ES9 ParB domain protein nuclease CEJ55_15800 ENOG4108X9F tail fiber protein CEJ55_15805 ENOG4105UZW Tail fiber assembly protein CEJ55_15810 ENOG4105MN3 Resolvase CEJ55_15815 ENOG4105W3V DNA-binding, transcriptional regulator CEJ55_15820 ENOG4108RW8 Universal stress protein F CEJ55_15825 ENOG4105FCK Membrane CEJ55_15835 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CEJ55_15845 ENOG41090X5 Heat shock protein hslJ CEJ55_15850 ENOG4105C5I Dehydrogenase CEJ55_15855 ENOG4107H52 Dicarboxylate transport CEJ55_15860 ENOG410689M (LipO)protein CEJ55_15865 ENOG4105WXT Conserved Protein CEJ55_15870 ENOG4108WFR AraC Family Transcriptional Regulator CEJ55_15875 ENOG4105C26 Dehydrogenase CEJ55_15880 ENOG4105F11 amine oxidase CEJ55_15885 ENOG4105DXM phenylacetic acid degradation protein CEJ55_15890 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit CEJ55_15895 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit CEJ55_15900 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit CEJ55_15905 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit CEJ55_15910 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEJ55_15915 ENOG4105E39 Enoyl-CoA hydratase CEJ55_15920 ENOG4108UKI Enoyl-CoA hydratase CEJ55_15925 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase CEJ55_15930 ENOG4108ZJI phenylacetic acid degradation protein CEJ55_15935 ENOG4105CHU acetyl-coa acetyltransferase CEJ55_15940 ENOG4105DZS Phenylacetate-CoA ligase CEJ55_15945 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein CEJ55_15950 ENOG4108Z0R Transferase CEJ55_15955 ENOG4107S5I aldo keto reductase CEJ55_15965 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase CEJ55_15970 ENOG4108HPI phosphatidate Cytidylyltransferase CEJ55_15975 ENOG4105E8V Alpha Beta Hydrolase Fold protein CEJ55_15980 ENOG41077RS Phosphatase CEJ55_15990 ENOG4105CQ7 ATP-dependent helicase CEJ55_15995 ENOG4107DB1 DUF218 domain CEJ55_16000 ENOG4105C26 Dehydrogenase CEJ55_16005 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CEJ55_16010 ENOG4105CPW cytochrome b561 CEJ55_16015 ENOG4105UPP uncharacterized protein ydcA CEJ55_16020 ENOG4107NK6 Hok/gef family CEJ55_16025 ENOG4105C8Q Methyl-accepting chemotaxis CEJ55_16030 ENOG4105DDW LysR family Transcriptional regulator CEJ55_16035 ENOG4105E32 cytoplasmic protein CEJ55_16055 ENOG4105Z2P Protein of unknown function (DUF465) CEJ55_16060 ENOG4108Z9I -acetyltransferase CEJ55_16065 ENOG4107WE3 acetyltransferase YdcK CEJ55_16070 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein CEJ55_16075 ENOG41088CC tellurite resistance protein tehB CEJ55_16080 ENOG4108KKZ (LipO)protein CEJ55_16090 ENOG4105D7V transposase CEJ55_16095 ENOG4105DKK Benzoate CEJ55_16100 ENOG4108JCI Transcriptional regulator CEJ55_16105 ENOG4105CFP Peptidase U32 CEJ55_16110 ENOG4105RR0 Protein of unknown function (DUF2554) CEJ55_16120 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin CEJ55_16125 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEJ55_16130 ENOG4107TYH extracellular solute-binding protein family 1 CEJ55_16135 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEJ55_16140 ENOG4105D81 ABC transporter, permease CEJ55_16145 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component CEJ55_16165 ENOG410654E Membrane CEJ55_16170 ENOG4105R71 cytoplasmic protein CEJ55_16175 ENOG4108T9Y Inner membrane protein ydcZ CEJ55_16180 ENOG4108Z7F N-acetyltransferase CEJ55_16190 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein CEJ55_16195 ENOG4108WYP Transcriptional regulator CEJ55_16200 ENOG4105CHB tonB-dependent Receptor CEJ55_16215 ENOG4108NS2 receptor CEJ55_16220 ENOG4105C85 amino acid CEJ55_16225 ENOG4108N27 Glutathione S-transferase CEJ55_16250 ENOG4105CNA YD repeat protein CEJ55_16285 ENOG4105CNA YD repeat protein CEJ55_16290 ENOG4105CNA YD repeat protein CEJ55_16310 ENOG4108MEJ flavin reductase domain protein CEJ55_16315 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase CEJ55_16320 ENOG4105JAB phenazine biosynthesis protein, phzf family CEJ55_16325 ENOG4105D0D Nitrate reductase 2, gamma subunit CEJ55_16330 ENOG4108NZN Respiratory nitrate reductase 2 delta chain CEJ55_16335 ENOG4108IUE nitrate reductase beta subunit CEJ55_16340 ENOG4105CRU nitrate reductase, alpha subunit CEJ55_16345 ENOG4107QND Nitrite extrusion protein CEJ55_16350 ENOG4108UI3 Leucine Rich repeat CEJ55_16360 ENOG4105RPH Inner membrane protein YddG CEJ55_16365 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEJ55_16370 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEJ55_16375 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CEJ55_16380 ENOG4108MG3 formate dehydrogenase CEJ55_16385 ENOG41084S7 Plasmid maintenance system antidote protein CEJ55_16390 ENOG4105DQ4 alcohol dehydrogenase CEJ55_16400 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein CEJ55_16405 ENOG4105TPS biofilm-dependent modulation protein CEJ55_16415 ENOG4108Z9K Osmotically inducible protein CEJ55_16420 ENOG4107H6U ABC transporter CEJ55_16425 ENOG4105C3U ABC transporter CEJ55_16430 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEJ55_16435 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEJ55_16440 ENOG4105DEF Extracellular solute-binding protein, family 5 CEJ55_16445 ENOG4108UQS dipeptidase CEJ55_16450 ENOG4105BZU Histidine kinase CEJ55_16460 ENOG4105F32 YngK protein CEJ55_16465 ENOG4105E5D amino acid CEJ55_16470 ENOG4105CVK Glutamate decarboxylase CEJ55_16475 ENOG4107RAN Peptidase, M16 CEJ55_16480 ENOG4105PE1 Receptor CEJ55_16485 ENOG4105CQ0 ABC transporter CEJ55_16490 ENOG4105C4X radical SAM domain protein CEJ55_16495 ENOG4105ENH Sulfatase CEJ55_16500 ENOG4105Z68 AraC Family Transcriptional Regulator CEJ55_16510 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit CEJ55_16515 ENOG4106PIH fimbrial-like protein ydeQ CEJ55_16520 ENOG4106318 fimbrial-like protein YdeR CEJ55_16525 ENOG4108WDE Fimbrial protein CEJ55_16530 ENOG4105CW0 outer membrane usher protein CEJ55_16540 ENOG4108RQP Major type 1 subunit fimbrin CEJ55_16560 ENOG4105CAF HipA N-terminal domain protein CEJ55_16565 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein CEJ55_16580 ENOG4105DKT Transcriptional regulator CEJ55_16595 ENOG4105F5R ABC transporter CEJ55_16600 ENOG4105D4B ABC, transporter CEJ55_16610 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound CEJ55_16620 ENOG4105FFC UPF0187 protein CEJ55_16640 ENOG4105BZU Histidine kinase CEJ55_16650 ENOG4105M0C cytoplasmic protein CEJ55_16655 ENOG4105CSV Glutaminase CEJ55_16660 ENOG4105C26 Dehydrogenase CEJ55_16665 ENOG4105EGI Transcriptional regulator CEJ55_16685 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes CEJ55_16690 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF CEJ55_16695 ENOG4106DNR multiple antibiotic resistance protein CEJ55_16700 ENOG4105CS2 ec 3.2.1.21 CEJ55_16710 ENOG4105VCP PTS System CEJ55_16715 ENOG4105CK1 PTS System CEJ55_16725 ENOG4105FDP GntR family transcriptional regulator CEJ55_16730 ENOG4108594 Permease of the drug metabolite transporter CEJ55_16735 ENOG4105E5W Transporter CEJ55_16745 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria CEJ55_16750 ENOG4108YDI single-species biofilm formation on inanimate substrate CEJ55_16755 ENOG4108WTK competence damage-inducible protein CEJ55_16765 ENOG4105DGW oligopeptidase A CEJ55_16775 ENOG4105EMU Dehydrogenase CEJ55_16780 ENOG4107XBN GntR Family Transcriptional Regulator CEJ55_16785 ENOG41061EV selenium-binding protein YdfZ CEJ55_16790 ENOG4105DEI Mannitol dehydrogenase CEJ55_16800 ENOG4105CPQ Dehydrogenase CEJ55_16805 ENOG4105CXK mandelate racemase muconate lactonizing CEJ55_16825 ENOG4108MK9 spermidine N(1)-acetyltransferase CEJ55_16835 ENOG4105KBG Protein of unknown function (DUF1161) CEJ55_16840 ENOG4107QY8 reductase CEJ55_16845 ENOG4105C3J Cysteine desulfurase CEJ55_16850 ENOG4105QAX Iron-sulfur CEJ55_16855 ENOG4107KGK dmso reductase anchor subunit CEJ55_16860 ENOG4108NEM leader-binding protein dmsD CEJ55_16865 ENOG4105CMQ Chloride channel CEJ55_16870 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CEJ55_16875 ENOG4105DAG ROK family CEJ55_16880 ENOG4106NZI LysR family Transcriptional regulator CEJ55_16885 ENOG4105D94 Major Facilitator Superfamily CEJ55_16905 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CEJ55_16925 ENOG4105DSF transport protein CEJ55_16930 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CEJ55_16935 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CEJ55_16940 ENOG4105C5D exported protein CEJ55_16950 ENOG4105D5Q Arginine ornithine antiporter CEJ55_16960 ENOG4105RA2 Membrane CEJ55_16965 ENOG4107EXC regulatoR CEJ55_16970 ENOG4105JJR Histidine kinase CEJ55_16980 ENOG4105C9Q fumarate hydratase class II CEJ55_16985 ENOG4107GFK fumarate CEJ55_16990 ENOG4105EIP mannose-6-phosphate isomerase CEJ55_16995 ENOG4106J39 exported protein CEJ55_17000 ENOG4108QNI outer membrane porin protein CEJ55_17005 ENOG4105CT4 transporter CEJ55_17010 ENOG4105CNT hydrolase family 2 CEJ55_17015 ENOG4105XEA Tetr family transcriptional regulator CEJ55_17020 ENOG4107ZQV short-chain dehydrogenase reductase CEJ55_17025 ENOG4107P2S Transcriptional regulator CEJ55_17030 ENOG4105CI1 PTS System CEJ55_17035 ENOG4105C87 Aminotransferase class I and II CEJ55_17045 ENOG4105D9R oxidoreductase CEJ55_17050 ENOG4106C6R beta-lactam resistance protein CEJ55_17060 ENOG4105QZ5 OriC-binding nucleoid-associated protein CEJ55_17065 ENOG4105M9B inner membrane protein ydgK CEJ55_17090 ENOG4108UQQ Electron transport complex CEJ55_17100 ENOG4105CSM endonuclease III CEJ55_17110 ENOG4105DUX Transporter CEJ55_17115 ENOG4108K3A Glutathione S-transferase CEJ55_17120 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) CEJ55_17135 ENOG410642K Lysozyme inhibitor CEJ55_17145 ENOG4108XTF Outer Membrane Lipoprotein CEJ55_17160 ENOG4105Y49 secretion protein, HlyD family CEJ55_17165 ENOG4105DSW Fusaric acid resistance protein CEJ55_17170 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEJ55_17175 ENOG4107RGM aldo keto reductase CEJ55_17180 ENOG4105XZD Fe-S protein CEJ55_17185 ENOG4108WUH Transcriptional regulator, TetR family CEJ55_17190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEJ55_17195 ENOG4108UYE Lactoylglutathione lyase CEJ55_17205 ENOG4107QRT dEAD DEAH box helicase CEJ55_17210 ENOG4105M2J Glutaredoxin CEJ55_17215 ENOG4105K4H Nlp p60 protein CEJ55_17220 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEJ55_17225 ENOG4105F27 Major Facilitator CEJ55_17245 ENOG4105F52 Transcriptional regulator CEJ55_17250 ENOG4105CZQ inner membrane transport protein YdhC CEJ55_17255 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CEJ55_17260 ENOG4108R6K riboflavin synthase, subunit alpha CEJ55_17285 ENOG4105N0V mono-oxygenase ydhR CEJ55_17290 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain CEJ55_17295 ENOG4108Y7C Conserved Protein CEJ55_17300 ENOG4108NWD Cytochrome CEJ55_17305 ENOG4108393 oxidoreductase Fe-S subunit CEJ55_17310 ENOG4105JVW CEJ55_17315 ENOG4105WE2 aldehyde ferredoxin oxidoreductase CEJ55_17320 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein CEJ55_17325 ENOG4105RFR Protein of unknown function (DUF2767) CEJ55_17330 ENOG4105CA9 Pyruvate kinase CEJ55_17335 ENOG4105KMX major outer membrane lipoprotein CEJ55_17340 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CEJ55_17355 ENOG4105JRK feS assembly protein SufD CEJ55_17360 ENOG4105C3K feS assembly ATPase SufC CEJ55_17365 ENOG4105DIW FeS assembly protein SUFB CEJ55_17370 ENOG4108Z4V iron-sulfur cluster assembly CEJ55_17375 ENOG410671Z uncharacterized protein ydiH CEJ55_17380 ENOG4105KA0 thioesterase Superfamily protein CEJ55_17385 ENOG4105CQB FAD linked oxidase domain protein CEJ55_17395 ENOG4105IPI Membrane CEJ55_17405 ENOG4105SUA Ydil protein CEJ55_17410 ENOG4105EMV Major Facilitator CEJ55_17415 ENOG4105EMV Major Facilitator CEJ55_17430 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) CEJ55_17435 ENOG4105C1G acyl-Coa dehydrogenase CEJ55_17440 ENOG4105W4W Transcriptional regulator CEJ55_17450 ENOG4105CV7 Electron transfer flavoprotein CEJ55_17455 ENOG4105C10 Electron transfer flavoprotein CEJ55_17460 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CEJ55_17465 ENOG41090P5 ferredoxin-like protein CEJ55_17470 ENOG4105CEY Amp-dependent synthetase and ligase CEJ55_17475 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CEJ55_17490 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEJ55_17495 ENOG4106EDX Hemin uptake protein CEJ55_17505 ENOG4108TC0 Diguanylate phosphodiesterase CEJ55_17510 ENOG4108QBX (LipO)protein CEJ55_17520 ENOG4108V06 Glutathione peroxidase CEJ55_17550 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) CEJ55_17555 ENOG41082NX 50s ribosomal protein l35 CEJ55_17580 ENOG4108NE3 Salt-induced outer membrane protein CEJ55_17585 ENOG4105DE4 1-phosphofructokinase CEJ55_17590 ENOG4105P10 Uncharacterized protein ydiZ CEJ55_17595 ENOG4105FGM Fructosamine kinase CEJ55_17600 ENOG4107PN8 YfeABCD locus regulator CEJ55_17605 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CEJ55_17610 ENOG4107K5X Membrane-bound metal-dependent hydrolase CEJ55_17615 ENOG4108ETY sodium dicarboxylate symporter CEJ55_17635 ENOG4105CH6 catalase CEJ55_17645 ENOG4105F8D glycoside hydrolase family 4 CEJ55_17650 ENOG4105EZV Transcriptional regulator CEJ55_17655 ENOG4105VCP PTS System CEJ55_17660 ENOG4105CK1 PTS System CEJ55_17665 ENOG4105VZJ PTS System CEJ55_17675 ENOG4105KKI DNA-binding transcriptional activator OsmE CEJ55_17685 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) CEJ55_17695 ENOG4108SPG Periplasmic Protein CEJ55_17730 ENOG4105CGK Exodeoxyribonuclease III CEJ55_17735 ENOG4108RSN SNARE associated Golgi CEJ55_17740 ENOG4108KCW iron-sulfur cluster binding CEJ55_17745 ENOG4108N5C SNARE associated Golgi protein-related protein CEJ55_17750 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) CEJ55_17755 ENOG4105VNH ABC transporter solute-binding protein CEJ55_17760 ENOG4105CXZ ABC transporter, permease CEJ55_17765 ENOG4108VGW abc transporter atp-binding protein CEJ55_17770 ENOG4107RM6 sulfurtransferase CEJ55_17775 ENOG4108T9J Cdp-alcohol phosphatidyltransferase CEJ55_17780 ENOG4105M6F mutator MutT protein CEJ55_17785 ENOG4105MTM Protein of unknown function (DUF1496) CEJ55_17790 ENOG4105D82 Glutamate dehydrogenase CEJ55_17795 ENOG41065FB inner membrane protein ynji CEJ55_17800 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CEJ55_17815 ENOG41069NU Nitroreductase CEJ55_17825 ENOG4105D07 Signal peptide peptidase, SppA CEJ55_17830 ENOG4105HDK L-asparaginase CEJ55_17835 ENOG4108RWI nicotinamidase CEJ55_17840 ENOG4108KUU Inner membrane metabolite transport protein ydjE CEJ55_17845 ENOG4105E98 transcriptional regulator DeoR family CEJ55_17850 ENOG4105CPC Aldo Keto reductase CEJ55_17855 ENOG4107UH8 sugar kinase CEJ55_17860 ENOG4105D2N Aldolase CEJ55_17865 ENOG4105CPQ Dehydrogenase CEJ55_17870 ENOG4107TE1 transport protein CEJ55_17875 ENOG4105CPQ Dehydrogenase CEJ55_17880 ENOG4105VUT cytoplasmic protein CEJ55_17890 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CEJ55_17895 ENOG4105DSB aldose 1-epimerase CEJ55_17900 ENOG4105CV8 reductase CEJ55_17905 ENOG4105GNX MltA-interacting MipA family protein CEJ55_17910 ENOG4105CYN Serine protein kinase CEJ55_17920 ENOG4106KTS Inner membrane protein yeaI CEJ55_17925 ENOG4108KHP Diguanylate cyclase CEJ55_17930 ENOG4108KXH Ybak prolyl-tRNA synthetase associated CEJ55_17945 ENOG4105R1U AraC Family Transcriptional Regulator CEJ55_17950 ENOG4105DJ2 Major Facilitator Superfamily CEJ55_17955 ENOG4105K78 MarR family Transcriptional regulator CEJ55_17960 ENOG4105UCG Domain of unknown function (DUF333) CEJ55_17965 ENOG410620I Diguanylate cyclase CEJ55_17970 ENOG4106G4W CEJ55_17980 ENOG4105Y3U Transglycosylase-associated protein CEJ55_17985 ENOG4105D7V transposase CEJ55_17990 ENOG4108RS6 transposase CEJ55_17995 ENOG4105YP6 Domain of unknown function (DUF1869) CEJ55_18000 ENOG4108YS1 cytoplasmic protein CEJ55_18010 ENOG4105EJC lysr family transcriptional regulator CEJ55_18015 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CEJ55_18020 ENOG4105C94 Transporter CEJ55_18025 ENOG4105DVW rieske (2Fe-2S) CEJ55_18030 ENOG4105E3J oxidoreductase CEJ55_18035 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CEJ55_18040 ENOG4105CEY Amp-dependent synthetase and ligase CEJ55_18045 ENOG4105Y4Z Outer Membrane Lipoprotein CEJ55_18050 ENOG41072GX Peptidase M22 Glycoprotease CEJ55_18055 ENOG4105DVT helicase CEJ55_18060 ENOG4105M4H endoribonuclease L-psp CEJ55_18065 ENOG4105V2F Uncharacterized protein yoac CEJ55_18075 ENOG4105CRQ synthase (Component I) CEJ55_18085 ENOG4105EJQ L-serine dehydratase CEJ55_18090 ENOG4107XTP (EAL) domain protein CEJ55_18095 ENOG4105EE5 Membrane protein terC CEJ55_18110 ENOG4108EQA pts system CEJ55_18115 ENOG4105ETZ PTS System CEJ55_18120 ENOG4105F3R pts system mannose fructose sorbose family iid CEJ55_18140 ENOG4105DHI Methyltransferase CEJ55_18145 ENOG4105VEQ Cold shock protein CEJ55_18150 ENOG410610J Protein of unknown function (DUF2627) CEJ55_18160 ENOG4105Q3Y exported protein CEJ55_18170 ENOG4105TIK CEJ55_18175 ENOG4105J4Q Transcriptional regulator CEJ55_18180 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEJ55_18190 ENOG4105CN1 protease CEJ55_18200 ENOG4108ZGC gaf domain protein CEJ55_18205 ENOG4105H2K paraquat-inducible protein a CEJ55_18210 ENOG4105DY2 Paraquat-inducible protein b CEJ55_18220 ENOG4105WT8 Protein of unknown function (DUF1480) CEJ55_18225 ENOG4105UVW uncharacterized protein yebW CEJ55_18230 ENOG4108R1E Serine threonine protein phosphatase 1 CEJ55_18235 ENOG4105NKT exported protein CEJ55_18240 ENOG4108PNC copper resistance CEJ55_18245 ENOG4105FXM Copper resistance protein CEJ55_18250 ENOG4105MPK DNA polymerase III subunit theta CEJ55_18255 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CEJ55_18260 ENOG4105UMD exodeoxyribonuclease X CEJ55_18265 ENOG4105CUG Oligopeptidase b CEJ55_18275 ENOG4108Q2J Inner membrane protein YebE CEJ55_18280 ENOG4105RSZ secreted protein CEJ55_18285 ENOG4105X2V dna damage-inducible protein CEJ55_18295 ENOG4108UHU Aldolase CEJ55_18300 ENOG4105C01 Dihydroxy-acid dehydratase CEJ55_18305 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CEJ55_18310 ENOG4106KNT transcriptional regulator CEJ55_18315 ENOG4105CA9 Pyruvate kinase CEJ55_18320 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CEJ55_18325 ENOG4105DR5 peptidase CEJ55_18330 ENOG4105NXV High-affinity zinc uptake system protein CEJ55_18335 ENOG4105FDK ABC transporter CEJ55_18340 ENOG4105FAV ABC, transporter CEJ55_18360 ENOG4107S01 Repressor protein MetJ CEJ55_18370 ENOG4105CDY transcriptional regulatory protein CEJ55_18375 ENOG4108TIT dATP pyrophosphohydrolase CEJ55_18385 ENOG4105D3W isochorismatase CEJ55_18390 ENOG41081XQ Conserved Protein CEJ55_18395 ENOG4105WJG Glutathione CEJ55_18410 ENOG4107QY8 reductase CEJ55_18415 ENOG4105CUW cytochrome C-TYPE protein CEJ55_18425 ENOG4106ZCM YecM protein CEJ55_18445 ENOG4105W13 flagellar protein CEJ55_18450 ENOG4105D7B Flagellar biosynthesis protein flha CEJ55_18455 ENOG4105D00 flagellar biosynthetic protein flhB CEJ55_18460 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CEJ55_18465 ENOG4108VYJ response regulator receiver protein CEJ55_18470 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) CEJ55_18475 ENOG4105BZU Histidine kinase CEJ55_18480 ENOG4105C8Q Methyl-accepting chemotaxis CEJ55_18485 ENOG4105C8Q Methyl-accepting chemotaxis CEJ55_18490 ENOG4108V3W Chemotaxis protein, CheW CEJ55_18495 ENOG4105CBS Chea signal transduction histidine kinase CEJ55_18500 ENOG4105ER2 Ompa motb domain protein CEJ55_18505 ENOG4107RD7 Flagellar Motor Protein, MotA CEJ55_18510 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CEJ55_18520 ENOG4108VA4 Universal stress protein CEJ55_18530 ENOG4108K4C ec 3.1.3.12 CEJ55_18535 ENOG4105CNN ABC, transporter CEJ55_18540 ENOG4105C2J ABC transporter CEJ55_18545 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator CEJ55_18555 ENOG4108UEC Ferritin-like protein CEJ55_18560 ENOG4105N4N Protein of unknown function (DUF2766) CEJ55_18570 ENOG4105P23 (LipO)protein CEJ55_18575 ENOG41090A1 ferritin CEJ55_18580 ENOG4105VVZ metal-binding protein CEJ55_18585 ENOG4105E0U tyrosine-specific transport protein CEJ55_18590 ENOG4106RHG Yeca family CEJ55_18610 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase CEJ55_18620 ENOG4105WH1 Two component transcriptional regulator luxr family CEJ55_18625 ENOG4105XVG cytoplasmic protein CEJ55_18630 ENOG4105VJY transcriptional regulator CEJ55_18635 ENOG4105CDA abc transporter atp-binding protein CEJ55_18640 ENOG4105E5Q amino acid AbC transporter CEJ55_18650 ENOG4105EAB amino acid AbC transporter CEJ55_18660 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEJ55_18665 ENOG4105I03 Flagellin CEJ55_18670 ENOG4105DTS flagellar hook-associated CEJ55_18675 ENOG4105MQ3 flagellar protein FliS CEJ55_18680 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) CEJ55_18685 ENOG4105E5K Alpha-amylase CEJ55_18690 ENOG4108W9D (LipO)protein CEJ55_18700 ENOG41066VF YeeE YedE family protein CEJ55_18705 ENOG4105KSU Redox protein CEJ55_18710 ENOG4108RAV Conserved protein CEJ55_18725 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CEJ55_18730 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEJ55_18735 ENOG41090PJ Flagellar assembly protein CEJ55_18740 ENOG4108JIR Flagellum-specific ATP synthase CEJ55_18745 ENOG4105GSA Flagellar export protein flij CEJ55_18750 ENOG4105WF4 Flagellar hook-length control protein CEJ55_18755 ENOG4107ZI8 flagellar basal body-associated protein flil CEJ55_18760 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEJ55_18765 ENOG4105DD5 Flagellar motor switch protein CEJ55_18770 ENOG4105K0P flagellar biosynthesis protein CEJ55_18775 ENOG4105CN7 Flagellar biosynthetic protein FliP CEJ55_18780 ENOG4105VS8 Flagellar biosynthetic protein fliq CEJ55_18785 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CEJ55_18790 ENOG4107TKS colanic acid capsular biosynthesis activation protein A CEJ55_18805 ENOG4105YX3 cellular response to acidity CEJ55_18825 ENOG4105VNZ cytoplasmic protein CEJ55_18830 ENOG4105CKW Inner membrane protein yedI CEJ55_18835 ENOG4105FDR Membrane CEJ55_18840 ENOG41090BB DNA mismatch endonuclease (vsr) CEJ55_18845 ENOG4105DVF Cytosine-specific methyltransferase CEJ55_18850 ENOG4105EST Metal Dependent Phosphohydrolase CEJ55_18855 ENOG4105Y0K Inner membrane protein YedR CEJ55_18860 ENOG4105FCK Membrane CEJ55_18875 ENOG4107ZY3 Histidine kinase CEJ55_18880 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEJ55_18885 ENOG4105VT2 5-hydroxyisourate hydrolase CEJ55_18900 ENOG4108MEK Metal-binding protein YodA CEJ55_18905 ENOG4108VKM cytochrome b561 CEJ55_19005 ENOG4105IM0 capsid protein CEJ55_19015 ENOG4105D07 Signal peptide peptidase, SppA CEJ55_19030 ENOG4105UZW Tail fiber assembly protein CEJ55_19075 ENOG4105RWQ Protein of unknown function (DUF1364) CEJ55_19155 ENOG4105CDU Replicative dna helicase CEJ55_19250 ENOG4105CSH Transporter CEJ55_19255 ENOG4105FYV Amp nucleosidase CEJ55_19260 ENOG4105CDY transcriptional regulatory protein CEJ55_19275 ENOG4105UQX Mate efflux family protein CEJ55_19285 ENOG4107R11 Transcriptional regulator CEJ55_19290 ENOG4106P55 Transcriptional regulator CEJ55_19300 ENOG4108PXI ErfK YbiS YcfS YnhG CEJ55_19315 ENOG4108YZT Adenosylcobinamide kinase CEJ55_19320 ENOG4108P62 biosynthesis protein (CbiG) CEJ55_19325 ENOG4107XVH Transcriptional regulator CEJ55_19330 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CEJ55_19335 ENOG4105KNY Microcompartments protein CEJ55_19340 ENOG4105EHR propanediol utilization protein pduB CEJ55_19345 ENOG4105DMB glycerol dehydratase CEJ55_19350 ENOG4105YCI dehydratase medium subunit CEJ55_19355 ENOG4108ZFT Dehydratase small subunit CEJ55_19360 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit CEJ55_19370 ENOG4105KNY Microcompartments protein CEJ55_19375 ENOG4105KNY Microcompartments protein CEJ55_19380 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) CEJ55_19390 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CEJ55_19400 ENOG4108EKI Dehydrogenase CEJ55_19405 ENOG4108EKI Dehydrogenase CEJ55_19410 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) CEJ55_19420 ENOG4105M3W utilization protein CEJ55_19425 ENOG4105KTW ethanolamine utilization protein CEJ55_19435 ENOG4105DR8 Membrane CEJ55_19440 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) CEJ55_19445 ENOG4105DZ1 carboxypeptidase CEJ55_19450 ENOG4105CJB Exodeoxyribonuclease I CEJ55_19460 ENOG4105CUC YeeE YedE family protein CEJ55_19465 ENOG4105CUB amino acid CEJ55_19470 ENOG4105EQ1 Transcriptional regulator CEJ55_19475 ENOG4108535 NAD dependent epimerase/dehydratase family CEJ55_19480 ENOG4105KRQ Addiction module toxin, Txe YoeB family CEJ55_19485 ENOG4105VTW prevent-host-death family CEJ55_19505 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CEJ55_19515 ENOG4105ECC imidazole-glycerol-phosphate dehydratase CEJ55_19520 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) CEJ55_19535 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CEJ55_19555 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CEJ55_19560 ENOG4108RYC glycosyltransferase CEJ55_19565 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) CEJ55_19580 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) CEJ55_19600 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEJ55_19605 ENOG4105DMT epimerase dehydratase CEJ55_19610 ENOG4105G1A colanic acid biosynthesis protein CEJ55_19615 ENOG4107T8Q Glycosyl transferase (Group 1 CEJ55_19620 ENOG4105C74 pyruvyl transferase CEJ55_19625 ENOG4105PSV Polysaccharide Biosynthesis Protein CEJ55_19630 ENOG4105D3Q Sugar transferase CEJ55_19635 ENOG4107QKV phosphomannomutase CEJ55_19640 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CEJ55_19645 ENOG4106CD9 glycosyl transferase group 1 CEJ55_19650 ENOG4105FGF GDP-mannose mannosyl hydrolase CEJ55_19655 ENOG4105C30 Nad-dependent epimerase dehydratase CEJ55_19660 ENOG4105C0K Gdp-mannose 4,6-dehydratase CEJ55_19665 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF CEJ55_19670 ENOG4105ECJ Glycosyl Transferase CEJ55_19675 ENOG4108NYJ Colanic acid CEJ55_19680 ENOG4107RXY Glycosyl transferase CEJ55_19685 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB CEJ55_19690 ENOG41090RK glycosyl transferase CEJ55_19695 ENOG4105D75 Capsular exopolysaccharide family CEJ55_19700 ENOG4105KJF protein tyrosine phosphatase CEJ55_19705 ENOG4105DAY polysaccharide export protein CEJ55_19710 ENOG4105EE5 Membrane protein terC CEJ55_19715 ENOG4108GAE asmA family CEJ55_19725 ENOG4105DBI uridine monophosphokinase CEJ55_19730 ENOG4105BZU Histidine kinase CEJ55_19735 ENOG4105D03 DNA-3-methyladenine glycosylase II CEJ55_19740 ENOG4105R8A Heat shock protein CEJ55_19745 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding CEJ55_19750 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase CEJ55_19755 ENOG4108M24 von Willebrand factor, type A CEJ55_19775 ENOG4105BZS acriflavin resistance protein CEJ55_19785 ENOG4105EB3 Histidine kinase CEJ55_19790 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEJ55_19795 ENOG4105KWI UPF0339 protein CEJ55_19800 ENOG4105X54 addiction module antidote protein CEJ55_19810 ENOG4105CFP Peptidase U32 CEJ55_19820 ENOG41076Z6 Uncharacterized protein yegR CEJ55_19835 ENOG4107WTH Galactitol-1-phosphate dehydrogenase CEJ55_19840 ENOG4105DT3 PTS system, galactitol-specific IIc component CEJ55_19845 ENOG41090UW PTS System CEJ55_19850 ENOG41082GB PTS system galactitol-specific transporter subunit IIA CEJ55_19870 ENOG4105EIE fructose-bisphosphate aldolase CEJ55_19875 ENOG4105EAA nucleoside CEJ55_19880 ENOG4108KD5 ADP-ribosylation crystallin J1 CEJ55_19885 ENOG4108TFM Kinase, PfkB family CEJ55_19890 ENOG4105FDP GntR family transcriptional regulator CEJ55_19895 ENOG4108UQ1 hydrolase, family 25 CEJ55_19900 ENOG4105DWF phosphomethylpyrimidine kinase CEJ55_19920 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly CEJ55_19925 ENOG410662B Type-1 fimbrial protein CEJ55_19930 ENOG4105CW0 outer membrane usher protein CEJ55_19935 ENOG4108MQF Chaperone CEJ55_19940 ENOG41063W2 Fimbrial protein CEJ55_19950 ENOG41067AK Protein of unknown function (DUF2574) CEJ55_19955 ENOG4105D1F ATP-binding protein CEJ55_19965 ENOG4108KDT Molybdate metabolism regulator CEJ55_19970 ENOG4108KDT Molybdate metabolism regulator CEJ55_19980 ENOG4105KKX ATPase associated with various cellular activities aaa_5 CEJ55_19985 ENOG4105RD5 CEJ55_19990 ENOG4105DEG Vwa containing coxe family protein CEJ55_19995 ENOG410903U zinc ion binding CEJ55_20000 ENOG4108YCW (LipO)protein CEJ55_20005 ENOG4108W15 Protein of unknown function (DUF1456) CEJ55_20010 ENOG4108NEV two component transcriptional regulator, LytTR family CEJ55_20015 ENOG4108HRK Histidine kinase CEJ55_20020 ENOG4108XDN Transcriptional regulator CEJ55_20030 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CEJ55_20035 ENOG4108IJ8 ABC transporter CEJ55_20040 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CEJ55_20045 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CEJ55_20050 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CEJ55_20055 ENOG4105CXG d-lactate dehydrogenase CEJ55_20060 ENOG41061WM D-Alanyl-D-Alanine CEJ55_20065 ENOG41069YE inner membrane protein yohC CEJ55_20070 ENOG4105KHU inner membrane protein YohD CEJ55_20075 ENOG4105H9W Short-chain dehydrogenase reductase Sdr CEJ55_20080 ENOG4105ETP RND efflux system, outer membrane lipoprotein CEJ55_20100 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CEJ55_20110 ENOG41067MG lrgb family CEJ55_20120 ENOG4107GZ4 SanA protein CEJ55_20125 ENOG4105Y9N Membrane CEJ55_20130 ENOG4105BZ8 glutamate synthase CEJ55_20135 ENOG4107SJI Dehydrogenase CEJ55_20140 ENOG4108HWV )-transporter CEJ55_20145 ENOG4105C2J ABC transporter CEJ55_20150 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator CEJ55_20155 ENOG41060NJ transcriptional regulator CEJ55_20165 ENOG4105DHF Membrane CEJ55_20185 ENOG4105C4W S-formylglutathione hydrolase CEJ55_20190 ENOG4105D05 Receptor CEJ55_20200 ENOG4108IQI permease CEJ55_20210 ENOG4105DUM transcriptional regulator, lysR family CEJ55_20215 ENOG4105HMI Membrane CEJ55_20225 ENOG4105DD7 kinase (PfkB family CEJ55_20230 ENOG4105D9N nucleoside CEJ55_20240 ENOG4108Y4K DNA-binding transcriptional activator CEJ55_20245 ENOG4105D9N nucleoside CEJ55_20250 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) CEJ55_20255 ENOG4105DD7 kinase (PfkB family CEJ55_20260 ENOG4105DM4 PTS System CEJ55_20265 ENOG4105DE4 1-phosphofructokinase CEJ55_20270 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CEJ55_20275 ENOG4105S8Q sugar efflux transporter CEJ55_20280 ENOG4105KRS Proteinase inhibitor CEJ55_20290 ENOG4105DEI Mannitol dehydrogenase CEJ55_20295 ENOG4105CKI cobalamin synthesis protein CEJ55_20300 ENOG41076MN Phosphoesterase, PA-phosphatase related CEJ55_20305 ENOG4107TT5 NLP P60 protein CEJ55_20310 ENOG4105CXC rtn protein CEJ55_20315 ENOG4105E43 Extracellular solute-binding protein, family 5 CEJ55_20320 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CEJ55_20325 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CEJ55_20330 ENOG4108JQ5 ABC transporter CEJ55_20335 ENOG4105HG6 CEJ55_20345 ENOG4105C2C drug resistance transporter, Bcr CflA CEJ55_20350 ENOG4105I08 Pseudouridine synthase CEJ55_20360 ENOG4105CFI type iii restriction protein res subunit CEJ55_20380 ENOG4105E68 Sulfatase CEJ55_20400 ENOG4105WH1 Two component transcriptional regulator luxr family CEJ55_20405 ENOG4105KWW Biogenesis protein CEJ55_20410 ENOG4107QX9 Thiol disulfide interChange protein CEJ55_20415 ENOG4105DA4 cytochrome c-type biogenesis protein CEJ55_20425 ENOG4105X3C heme exporter protein CEJ55_20430 ENOG41060IM Heme exporter protein CEJ55_20435 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CEJ55_20440 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) CEJ55_20445 ENOG4105CUW cytochrome C-TYPE protein CEJ55_20450 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CEJ55_20455 ENOG4105GXZ Ferredoxin-type protein NapH CEJ55_20460 ENOG4108BGM Quinol dehydrogenase periplasmic component CEJ55_20470 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CEJ55_20475 ENOG4108ZNS ferredoxin-type protein NapF CEJ55_20495 ENOG4105IBP Cyclic peptide transporter CEJ55_20500 ENOG4105CF1 Alkylated DNA repair protein CEJ55_20505 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEJ55_20510 ENOG4105CJ2 (LipO)protein CEJ55_20515 ENOG4105FCK Membrane CEJ55_20530 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CEJ55_20535 ENOG41068CG regulatoR CEJ55_20540 ENOG4105BZU Histidine kinase CEJ55_20545 ENOG4105EDV vault protein CEJ55_20550 ENOG41081SK signal peptide protein CEJ55_20555 ENOG4107S52 alpha-2-macroglobulin domain protein CEJ55_20560 ENOG4108QJJ Protein of unknown function (DUF1175) CEJ55_20565 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) CEJ55_20570 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEJ55_20580 ENOG4107GHC outer membrane autotransporter CEJ55_20590 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEJ55_20595 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEJ55_20600 ENOG4105XPH Ferredoxin CEJ55_20605 ENOG4105FQR PH-inducible protein involved in stress response CEJ55_20615 ENOG4107R11 Transcriptional regulator CEJ55_20620 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CEJ55_20625 ENOG4105CXY transporter CEJ55_20630 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CEJ55_20640 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CEJ55_20645 ENOG4105DNE Transposase CEJ55_20650 ENOG4105CNV Aldolase CEJ55_20660 ENOG4108UII YfaZ family CEJ55_20710 ENOG4106GZG polymyxin resistance protein B CEJ55_20715 ENOG4105CEY Amp-dependent synthetase and ligase CEJ55_20725 ENOG4108IPT Naphthoate synthase CEJ55_20740 ENOG4105E4F Isochorismate synthase CEJ55_20745 ENOG4105TNS Conserved Protein CEJ55_20750 ENOG4107YB6 acetyltransferase, (GNAT) family CEJ55_20775 ENOG4105GDX Domain of unknown function (DUF1877) CEJ55_20785 ENOG4105C8S subunit m CEJ55_20790 ENOG4105D65 subunit l CEJ55_20795 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEJ55_20800 ENOG4107UFS subunit j CEJ55_20805 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEJ55_20815 ENOG4108IEH NADH dehydrogenase subunit g CEJ55_20820 ENOG4107QIZ NADH dehydrogenase CEJ55_20825 ENOG4105GKE subunit e CEJ55_20845 ENOG4107NQ8 LysR family Transcriptional regulator CEJ55_20855 ENOG4105CHM Aminotransferase CEJ55_20865 ENOG4107QWE )-transporter CEJ55_20870 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CEJ55_20885 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CEJ55_20890 ENOG4105C6K Malic enzyme CEJ55_20895 ENOG4105CSX c4-dicarboxylate anaerobic carrier CEJ55_20900 ENOG4105PTV Nudix Hydrolase CEJ55_20905 ENOG4108RE9 Phosphodiesterase CEJ55_20910 ENOG4108SHQ Glutathione S-transferase CEJ55_20915 ENOG4105CYM Glutathione S-transferase CEJ55_20920 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase CEJ55_20925 ENOG4105ECP epimerase CEJ55_20930 ENOG4105DNE Transposase CEJ55_20935 ENOG4108JEH abc transporter atp-binding protein CEJ55_20940 ENOG4106YG3 ABC transporter CEJ55_20945 ENOG4105DSP amino acid AbC transporter CEJ55_20950 ENOG4105E89 ABC transporter CEJ55_20955 ENOG4105E89 ABC transporter CEJ55_20960 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CEJ55_20965 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CEJ55_20970 ENOG4105E96 Colicin v production protein CEJ55_20975 ENOG4108S3P Sporulation domain protein CEJ55_20980 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CEJ55_20990 ENOG4105DQR SNARE associated Golgi CEJ55_21000 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEJ55_21010 ENOG4106WZ1 flagella biosynthesis regulator CEJ55_21015 ENOG4105F9N Major Facilitator Superfamily CEJ55_21025 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEJ55_21030 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) CEJ55_21035 ENOG4105MH2 YfcL protein CEJ55_21040 ENOG4108BPE -transporting atpase CEJ55_21045 ENOG4105EJ9 Membrane CEJ55_21075 ENOG4105US4 fimbrial-like protein yfcP CEJ55_21080 ENOG4105UGQ Fimbrial CEJ55_21085 ENOG4105NEV Fimbrial CEJ55_21090 ENOG4108FZ9 Chaperone CEJ55_21095 ENOG4106PG1 outer membrane usher protein CEJ55_21105 ENOG4108BY2 phosphohistidine phosphatase CEJ55_21120 ENOG4105KZW UPF0381 protein CEJ55_21130 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CEJ55_21145 ENOG410903C (LipO)protein CEJ55_21155 ENOG4105S64 Formate nitrite transporter CEJ55_21165 ENOG4105DFP Integrase CEJ55_21295 ENOG4108R1E Serine threonine protein phosphatase 1 CEJ55_21335 ENOG4105NY2 NinB protein CEJ55_21345 ENOG4105CDU Replicative dna helicase CEJ55_21430 ENOG41077V0 CPS-53 (KpLE1) prophage CEJ55_21470 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision CEJ55_21475 ENOG4105DFP Integrase CEJ55_21540 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CEJ55_21545 ENOG4105D7K pfkb domain protein CEJ55_21550 ENOG4108HKT sucrose-6-phosphate hydrolase CEJ55_21555 ENOG4106NDP Transcriptional regulator CEJ55_21570 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEJ55_21575 ENOG4105CW7 secretion protein, HlyD family CEJ55_21580 ENOG4108WQH regulatoR CEJ55_21585 ENOG4105BZU Histidine kinase CEJ55_21590 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F CEJ55_21595 ENOG4108N2Y auxin Efflux CEJ55_21600 ENOG4105CFN oxalyl-CoA decarboxylase CEJ55_21610 ENOG4108V08 YfdX protein CEJ55_21620 ENOG4105W9M Membrane CEJ55_21625 ENOG4105D1S lipid A biosynthesis CEJ55_21635 ENOG4105CHM Aminotransferase CEJ55_21640 ENOG4108HRK Histidine kinase CEJ55_21645 ENOG4105DY9 regulatoR CEJ55_21650 ENOG4108CIP transcriptional regulator CEJ55_21655 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CEJ55_21660 ENOG4105CN9 Peptidase m42 family protein CEJ55_21665 ENOG4105DC7 peptidase M24 CEJ55_21670 ENOG410863U PTS System CEJ55_21675 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) CEJ55_21690 ENOG4109076 Conserved Protein CEJ55_21700 ENOG4105D9N nucleoside CEJ55_21705 ENOG4108KMM Diguanylate cyclase CEJ55_21720 ENOG4105HZG regulatoR CEJ55_21725 ENOG4105GXM Putative transcription regulator (DUF1323) CEJ55_21755 ENOG4105CN8 Transcriptional regulator CEJ55_21765 ENOG4105EAA nucleoside CEJ55_21770 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CEJ55_21775 ENOG4108NFH Sugar hydrolase CEJ55_21780 ENOG4108M0I Transcriptional regulator CEJ55_21785 ENOG4105DHU Bile acid CEJ55_21790 ENOG4105VRT cytoplasmic protein CEJ55_21810 ENOG4105C6T cysteine synthase CEJ55_21815 ENOG4105KZ7 phosphocarrier protein hpr CEJ55_21820 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CEJ55_21825 ENOG4105C5Y PTS System CEJ55_21835 ENOG4105M0Y CEJ55_21840 ENOG4105C6T cysteine synthase CEJ55_21845 ENOG4108IJ6 ABC transporter CEJ55_21850 ENOG4105ECW sulfate abc transporter CEJ55_21855 ENOG4108I5D sulfate abc transporter CEJ55_21860 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CEJ55_21865 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CEJ55_21880 ENOG4105C5Y PTS System CEJ55_21885 ENOG4107S1E Beta-lactamase CEJ55_21890 ENOG4105EZR dyp-type peroxidase family protein CEJ55_21895 ENOG4105E7K (LipO)protein CEJ55_21900 ENOG4105QZU Inner membrane protein YfeZ CEJ55_21905 ENOG4108R6G acetyltransferase CEJ55_21910 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase CEJ55_21920 ENOG4108K3Z AraC family transcriptional regulator CEJ55_21925 ENOG4108X49 Ethanolamine utilization protein EutK CEJ55_21930 ENOG4106D67 ethanolamine utilization protein CEJ55_21940 ENOG4105CPD ethanolamine ammonia-lyase CEJ55_21945 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase CEJ55_21950 ENOG4105ENY Ethanolamine utilization protein eutH CEJ55_21955 ENOG4105C0A alcohol dehydrogenase CEJ55_21960 ENOG4107RWI ethanolamine utilization protein eutJ CEJ55_21965 ENOG4108EKI Dehydrogenase CEJ55_21970 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CEJ55_21975 ENOG4105KNY Microcompartments protein CEJ55_21980 ENOG4107WUY phosphate acetyltransferase CEJ55_21985 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase CEJ55_21990 ENOG4105NDK ethanolamine utilization protein CEJ55_21995 ENOG4106S4J ethanolamine utilization protein EutP CEJ55_22000 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place CEJ55_22005 ENOG4105C6K Malic enzyme CEJ55_22015 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEJ55_22020 ENOG4105CV1 Transketolase (EC 2.2.1.1) CEJ55_22025 ENOG4108PVD exported protein CEJ55_22035 ENOG4105BZ8 glutamate synthase CEJ55_22040 ENOG4105BZU Histidine kinase CEJ55_22045 ENOG4105BZS acriflavin resistance protein CEJ55_22055 ENOG4105KUZ arsenate reductase CEJ55_22070 ENOG4106KED esterase YpfH CEJ55_22075 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) CEJ55_22080 ENOG4105CGZ zinc metallopeptidase CEJ55_22085 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A CEJ55_22100 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CEJ55_22110 ENOG4105RH4 Glycine cleavage system transcriptional repressor CEJ55_22115 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CEJ55_22120 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) CEJ55_22125 ENOG4108JPZ Monovalent cation H antiporter subunit D CEJ55_22130 ENOG4107TDF Formate hydrogenlyase subunit 4 CEJ55_22140 ENOG4107WQX hydrogenase 4 membrane subunit CEJ55_22145 ENOG4108JPZ Monovalent cation H antiporter subunit D CEJ55_22150 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEJ55_22160 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit CEJ55_22165 ENOG4105I6X formate hydrogenlyase maturation CEJ55_22170 ENOG4108JUA Transcriptional regulator CEJ55_22175 ENOG4105TMB Formate nitrite transporter CEJ55_22180 ENOG4105TMB Formate nitrite transporter CEJ55_22190 ENOG4105C02 permease CEJ55_22195 ENOG4105ERG peptidase m48, ste24p CEJ55_22200 ENOG4105K89 arsenate reductase CEJ55_22210 ENOG4105C2W permease CEJ55_22230 ENOG4108V3E phosphoribosylglycinamide formyltransferase CEJ55_22235 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CEJ55_22240 ENOG4105C9X ppx gppa phosphatase CEJ55_22245 ENOG4105BZU Histidine kinase CEJ55_22255 ENOG41062G3 Protein of unknown function (DUF2633) CEJ55_22265 ENOG4108ZMA Outer membrane lipoprotein CEJ55_22270 ENOG41066DY Membrane CEJ55_22280 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CEJ55_22290 ENOG4105VPD cellular component movement CEJ55_22305 ENOG4105N21 Membrane CEJ55_22335 ENOG4108JQB penicillin-binding protein 1C CEJ55_22340 ENOG4105DN3 alpha-2-macroglobulin domain protein CEJ55_22345 ENOG4105KHC sulfurtransferase CEJ55_22350 ENOG4105YYA enhanced serine sensitivity protein SseB CEJ55_22360 ENOG4105WVQ Fe-S assembly protein IscX CEJ55_22365 ENOG4108ZIT Ferredoxin, 2FE-2S CEJ55_22385 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CEJ55_22410 ENOG4107XM9 (LipO)protein CEJ55_22415 ENOG4108MN2 Stationary phase inducible protein CsiE CEJ55_22420 ENOG4105D8G Major Facilitator superfamily CEJ55_22425 ENOG4108W5M transcriptional regulator CEJ55_22430 ENOG4105FUY alpha subunit CEJ55_22455 ENOG4108SB3 DoxX Family CEJ55_22460 ENOG4108ZKT aldose 1-epimerase CEJ55_22465 ENOG4105CPQ Dehydrogenase CEJ55_22470 ENOG4105CNN ABC, transporter CEJ55_22475 ENOG4108F37 ATP-binding component of a transport system CEJ55_22480 ENOG4105FCA ABC transporter periplasmic-binding protein YphF CEJ55_22485 ENOG4107HQ7 repeat protein CEJ55_22490 ENOG4108NZE NAGC-like transcriptional regulator CEJ55_22500 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEJ55_22505 ENOG4108YZA Nitrogen regulatory protein pii CEJ55_22510 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEJ55_22515 ENOG4108SKK alpha helix protein CEJ55_22520 ENOG4107WP9 Histidine kinase CEJ55_22525 ENOG4108ETH Formylglycinamide ribotide synthetase CEJ55_22540 ENOG4108Z6B deaminase CEJ55_22545 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CEJ55_22550 ENOG4106G6Q Transcriptional regulator CEJ55_22580 ENOG4105UZW Tail fiber assembly protein CEJ55_22590 ENOG410685N tail fiber protein CEJ55_22715 ENOG4108N0N Phage Terminase Large Subunit CEJ55_22745 ENOG4105HRS Antitermination protein CEJ55_22760 ENOG4108XTP Transcriptional regulator CEJ55_22840 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CEJ55_22865 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CEJ55_22890 ENOG4105C3F Signal peptidase i CEJ55_22900 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CEJ55_22905 ENOG4105VQK sigma E regulatory protein, MucB RseB CEJ55_22910 ENOG41069PW sigma-e factor negative regulatory protein CEJ55_22915 ENOG4105EMN RNA polymerase sigma factor CEJ55_22920 ENOG4108IYU L-aspartate oxidase CEJ55_22930 ENOG4105C1J atp-dependent rna helicase CEJ55_22945 ENOG41090KR LysR family transcriptional Regulator CEJ55_22965 ENOG4105EIB trna rrna methyltransferase CEJ55_22975 ENOG4105K63 Thioredoxin CEJ55_22980 ENOG4106IUH DTW domain containing protein CEJ55_22985 ENOG4105CD5 CoA-binding domain protein CEJ55_22990 ENOG4105JIM Phosphatidylserine synthase CEJ55_22995 ENOG4105T42 (LipO)protein CEJ55_23000 ENOG4105CSH Transporter CEJ55_23030 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEJ55_23035 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CEJ55_23040 ENOG4105C34 Pseudouridine synthase CEJ55_23045 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CEJ55_23055 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CEJ55_23060 ENOG4105CQC Prephenate dehydratase CEJ55_23065 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CEJ55_23070 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEJ55_23075 ENOG4105QP9 Protein of unknown function (DUF2799) CEJ55_23080 ENOG4108WS1 CEJ55_23085 ENOG4108KHX Diguanylate cyclase CEJ55_23090 ENOG41090EK ompa motb domain protein CEJ55_23115 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CEJ55_23120 ENOG4106KVJ cytochrome C assembly protein CEJ55_23125 ENOG4108JU6 CBS domain protein CEJ55_23145 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CEJ55_23150 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CEJ55_23155 ENOG4105VDB UPF0125 protein CEJ55_23160 ENOG4108Z1B Cyclase dehydrase CEJ55_23180 ENOG4108MGN ATP-binding component of a transport system CEJ55_23220 ENOG4105E54 alpha-amylase CEJ55_23230 ENOG4105D5U fad dependent oxidoreductase CEJ55_23235 ENOG4105C26 Dehydrogenase CEJ55_23240 ENOG4108JPW Aminotransferase CEJ55_23245 ENOG4105C85 amino acid CEJ55_23250 ENOG4108PVQ transcriptional regulator CEJ55_23255 ENOG4109066 lysm domain bon superfamily protein CEJ55_23260 ENOG4105VPI YqaE family transport protein CEJ55_23265 ENOG41080HT Transcriptional regulator, arsr family CEJ55_23270 ENOG4108V62 Rhodanese domain protein CEJ55_23275 ENOG4108X73 DNA- binding protein CEJ55_23280 ENOG4108RNS Exports L-alanine (By similarity) CEJ55_23285 ENOG4108WMJ Protein of unknown function (DUF2002) CEJ55_23290 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) CEJ55_23295 ENOG4105WAZ (Glutaredoxin-like protein) NrdH CEJ55_23300 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) CEJ55_23305 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEJ55_23310 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEJ55_23315 ENOG4108IJ7 Glycine betaine CEJ55_23320 ENOG4108HQS Glycine betaine CEJ55_23325 ENOG4105GIJ Glycine betaine CEJ55_23335 ENOG4108UMN azlc family CEJ55_23340 ENOG4105ZED uncharacterized protein ygaH CEJ55_23345 ENOG4105NTK Transcriptional repressor Mpra CEJ55_23350 ENOG4105CW7 secretion protein, HlyD family CEJ55_23355 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEJ55_23370 ENOG4105W39 Membrane CEJ55_23375 ENOG4107VXZ Hydrolase CEJ55_23400 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CEJ55_23420 ENOG4107TH8 cina domain protein CEJ55_23425 ENOG4105CVE Lytic murein transglycosylase CEJ55_23430 ENOG410787A Pts system, glucitol sorbitol-specific CEJ55_23435 ENOG4105DZY Pts system, glucitol sorbitol-specific CEJ55_23440 ENOG4105VI0 Pts system, glucitol sorbitol-specific CEJ55_23445 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase CEJ55_23450 ENOG4105J92 DNA-binding transcriptional activator GutM CEJ55_23455 ENOG410804X Transcriptional regulator CEJ55_23460 ENOG4105C2X Arabinose 5-phosphate isomerase CEJ55_23480 ENOG4105C8H hydrogenase maturation protein Hypf CEJ55_23485 ENOG4108RC0 Electron transport protein CEJ55_23490 ENOG4105DDV Transcriptional regulator (LacI family CEJ55_23495 ENOG4105C5Y PTS System CEJ55_23500 ENOG4105CS2 ec 3.2.1.21 CEJ55_23505 ENOG4108MG9 hydrogenase 3 maturation protease CEJ55_23510 ENOG4105I6X formate hydrogenlyase maturation CEJ55_23515 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit CEJ55_23520 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit CEJ55_23525 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEJ55_23530 ENOG4107TDF Formate hydrogenlyase subunit 4 CEJ55_23535 ENOG4107R30 NADH dehydrogenase CEJ55_23540 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) CEJ55_23550 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA CEJ55_23555 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CEJ55_23560 ENOG4107RSS Hydrogenase accessory protein HypB CEJ55_23565 ENOG41083WG hydrogenase assembly chaperone CEJ55_23570 ENOG4105CQS hydrogenase expression formation protein HypD CEJ55_23575 ENOG4105C45 hydrogenase expression formation protein (HypE) CEJ55_23580 ENOG4108JUA Transcriptional regulator CEJ55_23585 ENOG4105VXR cytoplasmic protein CEJ55_23595 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) CEJ55_23600 ENOG4105MEW serine threonine protein phosphatase CEJ55_23605 ENOG4105MVE transcriptional regulator CEJ55_23615 ENOG4105G63 Type III effector Hrp-dependent CEJ55_23620 ENOG4105FB2 class II Aldolase CEJ55_23625 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CEJ55_23630 ENOG4105C6Z Gluconate CEJ55_23635 ENOG4105KZM cytoplasmic protein CEJ55_23640 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CEJ55_23645 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CEJ55_23655 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEJ55_23660 ENOG4108K5P (LipO)protein CEJ55_23695 ENOG4105N0Z inner membrane protein ygbE CEJ55_23715 ENOG4108MXK alkaline phosphatase isozyme conversion CEJ55_23720 ENOG4105PWE CRISPR-associated protein cas2 CEJ55_23725 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CEJ55_23735 ENOG4108VWQ crispr-associated protein CEJ55_23740 ENOG41060M0 Crispr-associated protein, cse4 family CEJ55_23750 ENOG4105CYR Crispr-associated protein, cse1 family CEJ55_23755 ENOG4105DTT CRISPR-associated helicase, cas3 CEJ55_23760 ENOG4107635 Hok Gef family protein CEJ55_23780 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CEJ55_23785 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CEJ55_23790 ENOG4105WQV ferredoxin-like protein CEJ55_23795 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator CEJ55_23800 ENOG4105YBM electron transfer flavoprotein subunit ygcQ CEJ55_23805 ENOG4106IKH Electron transfer flavoprotein CEJ55_23810 ENOG4105C54 Major Facilitator superfamily CEJ55_23815 ENOG4107R3A FAD linked oxidase domain protein CEJ55_23820 ENOG4105CHR reductase CEJ55_23825 ENOG4108ITV Inner membrane protein yqcE CEJ55_23830 ENOG4108CWB sugar kinase ygcE CEJ55_23835 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CEJ55_23860 ENOG4105DXN mazG family CEJ55_23865 ENOG4105MZG transcriptional modulator of maze toxin, mazf CEJ55_23870 ENOG4106A2Z transcriptional regulator antitoxin, MazE CEJ55_23875 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CEJ55_23885 ENOG4105BZU Histidine kinase CEJ55_23890 ENOG4105EQX glucarate dehydratase CEJ55_23895 ENOG4105EQX glucarate dehydratase CEJ55_23900 ENOG4105DJB Major Facilitator Superfamily CEJ55_23905 ENOG4105QDK Flavodoxin CEJ55_23910 ENOG4105DR9 pseudouridine synthase CEJ55_23915 ENOG4105WP7 tRNA pseudouridine synthase C CEJ55_23930 ENOG4105EWT decarboxylase family CEJ55_23935 ENOG4105C44 Serine transporter CEJ55_23940 ENOG4105EJQ L-serine dehydratase CEJ55_23950 ENOG4105C0A alcohol dehydrogenase CEJ55_23955 ENOG4107W7X Aldolase CEJ55_23960 ENOG4105EDR glucose galactose transporter CEJ55_23970 ENOG4105CMG Carbohydrate kinase CEJ55_23980 ENOG4107EDW L-fucose operon activator CEJ55_23990 ENOG4105M08 Membrane CEJ55_23995 ENOG4105ETT transcriptional Regulator, LysR family CEJ55_24000 ENOG4105M5B (LipO)protein CEJ55_24005 ENOG4105C9B Cysteine desulfurase CEJ55_24010 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CEJ55_24015 ENOG4105CUZ uba thif-type nad fad binding protein CEJ55_24020 ENOG4105CA3 membrane-bound lytic murein transglycosylase CEJ55_24045 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CEJ55_24050 ENOG4107QZM n-acetylglutamate synthase CEJ55_24055 ENOG4107QYX exodeoxyribonuclease v alpha CEJ55_24060 ENOG4107QKA exodeoxyribonuclease V beta CEJ55_24065 ENOG4107QXK peptidase CEJ55_24070 ENOG4105DSY exodeoxyribonuclease V, gamma CEJ55_24075 ENOG4105RVB Prepilin peptidase dependent protein c CEJ55_24080 ENOG4105SEN Protein of unknown function (DUF2509) CEJ55_24085 ENOG4105JCS prepilin peptidase dependent protein CEJ55_24090 ENOG4105IPU prepilin peptidase dependent protein A CEJ55_24105 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CEJ55_24120 ENOG4105EE5 Membrane protein terC CEJ55_24125 ENOG4105SUV lipoprotein YgdR CEJ55_24130 ENOG4105CPC Aldo Keto reductase CEJ55_24145 ENOG41060NJ transcriptional regulator CEJ55_24150 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CEJ55_24155 ENOG4105RQF LysR family Transcriptional regulator CEJ55_24165 ENOG4107QNK )-transporter CEJ55_24170 ENOG4105CHR reductase CEJ55_24180 ENOG4105CHU acetyl-coa acetyltransferase CEJ55_24185 ENOG4108MHD transport protein CEJ55_24190 ENOG4105ISV protein with bipartite regulator domain CEJ55_24195 ENOG4108TC1 Transcriptional regulator CEJ55_24200 ENOG4105FV3 CEJ55_24230 ENOG4108YAB Invasion protein CEJ55_24275 ENOG4108RBT type iii secretion CEJ55_24290 ENOG4108RC9 Type III secretion system protein CEJ55_24305 ENOG4108M6W surface presentation of antigens protein SpaS CEJ55_24310 ENOG4108M6W surface presentation of antigens protein SpaS CEJ55_24320 ENOG4108TN6 type iii secretion CEJ55_24330 ENOG41075IY surface presentation of antigens protein SpaP CEJ55_24345 ENOG4108T88 CEJ55_24355 ENOG4108K5P (LipO)protein CEJ55_24365 ENOG4105C7W Xanthine dehydrogenase CEJ55_24370 ENOG4108HR6 Dehydrogenase CEJ55_24375 ENOG4108UTP (2Fe-2S)-binding domain protein CEJ55_24380 ENOG4108JUB Transcriptional regulator CEJ55_24385 ENOG4105IW6 Carbamoyltransferase CEJ55_24390 ENOG4107RCH Diaminopropionate ammonia-lyase CEJ55_24395 ENOG4107S4Y M20 DapE family protein YgeY CEJ55_24405 ENOG4105C5B carbamate kinase CEJ55_24410 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family CEJ55_24415 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC CEJ55_24420 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase CEJ55_24425 ENOG4105BZ8 glutamate synthase CEJ55_24430 ENOG4107UUR Chlorohydrolase aminohydrolase CEJ55_24435 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase CEJ55_24440 ENOG4105C7W Xanthine dehydrogenase CEJ55_24445 ENOG4105C2W permease CEJ55_24450 ENOG4107QUY Guanine deaminase CEJ55_24455 ENOG4105C7N Xanthine uracil vitamin C permease CEJ55_24460 ENOG4108R8B oxidoreductase Fe-S subunit CEJ55_24465 ENOG4105BZ8 glutamate synthase CEJ55_24475 ENOG4105C2W permease CEJ55_24490 ENOG4105CRK lysyL-tRNA synthetase CEJ55_24500 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CEJ55_24505 ENOG4105T95 Thiol disulfide interChange protein CEJ55_24510 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEJ55_24515 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CEJ55_24520 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB CEJ55_24525 ENOG4105Y75 tpr repeat protein CEJ55_24545 ENOG4108UT2 hemolysin iii CEJ55_24555 ENOG4105CS2 ec 3.2.1.21 CEJ55_24560 ENOG4105CYX Short-chain dehydrogenase reductase Sdr CEJ55_24580 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CEJ55_24585 ENOG4105D0A hydroxylase CEJ55_24590 ENOG4107RAQ aminopeptidase CEJ55_24615 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CEJ55_24630 ENOG4108JQ1 Dehydrogenase CEJ55_24655 ENOG4105D5P Methylmalonyl-coA mutase CEJ55_24660 ENOG4105DJT lAO AO transport system ATPase CEJ55_24665 ENOG4108M7F enoyl-CoA hydratase isomerase CEJ55_24670 ENOG4105CYC Transferase CEJ55_24675 ENOG4105DEQ transcriptional regulator CEJ55_24680 ENOG4105MPN Membrane CEJ55_24685 ENOG4108ZUB Lysine exporter protein (Lyse ygga) CEJ55_24690 ENOG4105D64 Mechanosensitive ion channel CEJ55_24695 ENOG4105D2N Aldolase CEJ55_24730 ENOG4108JJB ABC transporter CEJ55_24735 ENOG4108JJB ABC transporter CEJ55_24740 ENOG4107Z1W Fructose transport system kinase CEJ55_24745 ENOG4108R4K DNA-binding, transcriptional regulator CEJ55_24750 ENOG4108Q8A Fructose-1,6-bisphosphatase CEJ55_24755 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein CEJ55_24760 ENOG4105CTS PTS system mannitol-specific CEJ55_24765 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia CEJ55_24770 ENOG4105CV1 Transketolase (EC 2.2.1.1) CEJ55_24775 ENOG4108K0D peptidase, M48 CEJ55_24790 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CEJ55_24815 ENOG4107QNK )-transporter CEJ55_24825 ENOG4105RWS endonuclease I CEJ55_24830 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CEJ55_24835 ENOG4105D7Z glutathione synthase CEJ55_24850 ENOG4105CZX twitching motility protein CEJ55_24855 ENOG4105DFA alanine racemase domain protein CEJ55_24860 ENOG4108VIA integral membrane protein CEJ55_24870 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CEJ55_24875 ENOG4105CSA Coproporphyrinogen iii oxidase CEJ55_24880 ENOG4106MH3 alpha helix chain CEJ55_24885 ENOG4105HDK L-asparaginase CEJ55_24890 ENOG4105K33 Periplasmic Protein CEJ55_24895 ENOG41090ED Protein with unknown function (DUF469) CEJ55_24910 ENOG4105CEN a g-specific adenine glycosylase CEJ55_24925 ENOG4105EAA nucleoside CEJ55_24930 ENOG4105CXN decarboxylase CEJ55_24940 ENOG4108UQV Membrane CEJ55_24955 ENOG4108I6E Sulfatase CEJ55_24960 ENOG4105T40 surface antigen msp4 family protein CEJ55_25095 ENOG4105UPP uncharacterized protein ydcA CEJ55_25100 ENOG4105CKT filamentous hemagglutinin CEJ55_25105 ENOG4105CKT filamentous hemagglutinin CEJ55_25115 ENOG4105CKT filamentous hemagglutinin