locus-tag class description FOA56_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOA56_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOA56_00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) FOA56_00030 ENOG410667J hydrolase FOA56_00035 ENOG410657R replicase EC 2.7 FOA56_00040 ENOG4105EMF GntR family transcriptional regulator FOA56_00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FOA56_00050 ENOG4108RTU Aldolase FOA56_00060 ENOG4105DJB Major Facilitator Superfamily FOA56_00070 ENOG4105D99 atp gtp-binding protein FOA56_00075 ENOG4105R2A (LipO)protein FOA56_00095 ENOG4105FDP GntR family transcriptional regulator FOA56_00100 ENOG4105CI1 PTS System FOA56_00110 ENOG4108AHD Transcriptional regulator FOA56_00115 ENOG4107RUZ Sss sodium solute transporter superfamily FOA56_00120 ENOG4105CBG Sulfatase FOA56_00125 ENOG4106DRA Inner membrane protein YidI FOA56_00130 ENOG4105VG5 Membrane FOA56_00135 ENOG4105JP4 Inner membrane protein yidG FOA56_00140 ENOG4105J13 transcriptional regulator FOA56_00145 ENOG4105E5M Multidrug resistance protein D FOA56_00160 ENOG4105C7K acetolactate synthase FOA56_00165 ENOG4105M71 acetolactate synthase 1 regulatory subunit FOA56_00170 ENOG4108KX4 response regulator FOA56_00175 ENOG4105BZU Histidine kinase FOA56_00180 ENOG4105CXY transporter FOA56_00185 ENOG4105CXY transporter FOA56_00195 ENOG4105C7N Xanthine uracil vitamin C permease FOA56_00200 ENOG4108SAJ Protein of unknown function (DUF1198) FOA56_00210 ENOG4105T8A Uncharacterized protein YicS FOA56_00215 ENOG4105D01 (LipO)protein FOA56_00220 ENOG4108UZ3 Transporter FOA56_00225 ENOG4105S8Q sugar efflux transporter FOA56_00240 ENOG4105CT4 transporter FOA56_00245 ENOG4105CJQ hydrolase, family 31 FOA56_00250 ENOG4105JV1 AsmA family FOA56_00255 ENOG4105C2W permease FOA56_00260 ENOG4105D6U Sodium Glutamate Symporter FOA56_00270 ENOG4105CB5 ATP-dependent DNA helicase recG FOA56_00275 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FOA56_00280 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOA56_00285 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FOA56_00290 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FOA56_00300 ENOG4105EN6 Membrane FOA56_00305 ENOG4105F5P DNA-damage-inducible protein d FOA56_00315 ENOG4105DSJ YicC domain protein FOA56_00340 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOA56_00355 ENOG4105W0E 50S ribosomal protein L33 FOA56_00370 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FOA56_00375 ENOG4105DKP glycosyl transferase, family 9 FOA56_00380 ENOG4107RJ7 Glycosyl transferase (Group 1 FOA56_00385 ENOG4107543 (lipo)polysaccharide FOA56_00390 ENOG4106AH0 Glycosyl Transferase FOA56_00405 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FOA56_00415 ENOG4105D16 lipopolysaccharide heptosyltransferase i FOA56_00420 ENOG4105XA0 heptosyltransferase ii FOA56_00430 ENOG4108SEH involved in lipopolysaccharide biosynthesis FOA56_00435 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FOA56_00445 ENOG4105K64 Glycosyl transferase, family 2 FOA56_00450 ENOG4105PXI polysaccharide deacetylase FOA56_00455 ENOG41063SB peptidase FOA56_00465 ENOG4107YZP Rhodanese domain protein FOA56_00470 ENOG4105VW4 glutaredoxin 3 FOA56_00485 ENOG4105D7W serine acetyltransferase FOA56_00490 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOA56_00500 ENOG41073TP transcriptional regulator FOA56_00505 ENOG4105DAA L-lactate FOA56_00510 ENOG4105EUR Domain-Containing protein FOA56_00515 ENOG4108WY4 inner membrane lipoprotein FOA56_00525 ENOG4108YYI Protein of unknown function (DUF2810) FOA56_00535 ENOG4105E61 Mannitol repressor protein FOA56_00545 ENOG4105CTS PTS system mannitol-specific FOA56_00550 ENOG4105FP6 Protein of unknown function (DUF3302) FOA56_00555 ENOG4105EFX secretion protein, HlyD family FOA56_00600 ENOG4108U78 Glutathione S-transferase FOA56_00610 ENOG4105EM7 Selenocysteine-specific translation elongation factor FOA56_00615 ENOG4105C0A alcohol dehydrogenase FOA56_00620 ENOG4105C26 Dehydrogenase FOA56_00630 ENOG4105KK7 inner membrane protein YiaW FOA56_00635 ENOG4105EFX secretion protein, HlyD family FOA56_00640 ENOG4108Q2M Transcriptional regulator FOA56_00645 ENOG4105GNX MltA-interacting MipA family protein FOA56_00655 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FOA56_00660 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FOA56_00665 ENOG4105H6Q decarboxylase FOA56_00670 ENOG4105CMG Carbohydrate kinase FOA56_00675 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FOA56_00680 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FOA56_00685 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FOA56_00690 ENOG4108R66 Conserved Protein FOA56_00700 ENOG4105J4Q Transcriptional regulator FOA56_00705 ENOG4108XIB electron transport protein ysaA FOA56_00710 ENOG4105JKW Valine--pyruvate aminotransferase FOA56_00715 ENOG4107T9C Alpha amylase catalytic region FOA56_00720 ENOG4108UR8 BAX protein FOA56_00725 ENOG4105T16 Transcriptional regulator (AraC family) FOA56_00730 ENOG4107RNG ABC transporter FOA56_00735 ENOG4105C2J ABC transporter FOA56_00740 ENOG4105DFW ABC transporter FOA56_00750 ENOG4105CMG Carbohydrate kinase FOA56_00755 ENOG410688U Inner membrane protein yiaB FOA56_00760 ENOG4108Z12 YiaAB two helix domain-containing protein FOA56_00765 ENOG4105MEV Acyl-transferase FOA56_00775 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FOA56_00785 ENOG41060TC Hok gef cell toxic protein FOA56_00790 ENOG4105VEQ Cold shock protein FOA56_00795 ENOG4105MVF Transcriptional regulator FOA56_00800 ENOG4106JH6 (LipO)protein FOA56_00810 ENOG4108ZG0 Ompa motb domain protein FOA56_00815 ENOG4107QY8 reductase FOA56_00820 ENOG4105HNP -acetyltransferase FOA56_00825 ENOG4108R3E Dna-3-methyladenine glycosylase i FOA56_00830 ENOG4105EAX Putative lipase FOA56_00835 ENOG4105FCD Major Facilitator FOA56_00840 ENOG4105DIJ Phosphoethanolamine transferase FOA56_00855 ENOG4105DEF Extracellular solute-binding protein, family 5 FOA56_00865 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOA56_00870 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOA56_00875 ENOG4105C3U ABC transporter FOA56_00880 ENOG4108JQ7 (ABC) transporter FOA56_00885 ENOG4105C44 Serine transporter FOA56_00920 ENOG4105D1V cellulose synthase operon protein YhjU FOA56_00925 ENOG4105WQA Cellulose biosynthesis protein BcsF FOA56_00930 ENOG4105U74 cellulose biosynthesis protein BcsE FOA56_00935 ENOG410661M cytoplasmic protein FOA56_00945 ENOG4107QZ7 Cellulose synthase catalytic subunit FOA56_00950 ENOG4107EEX Cellulose synthase regulator protein FOA56_00955 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FOA56_00960 ENOG4105EJG cellulose synthase FOA56_00965 ENOG4105BZU Histidine kinase FOA56_00975 ENOG4105CS0 peptidase FOA56_00985 ENOG4105CMB EAL domain-containing protein FOA56_00990 ENOG41066T0 asmA family FOA56_00995 ENOG4105CSH Transporter FOA56_01000 ENOG4107H3J ribonuclease FOA56_01005 ENOG4105CBN LysR family transcriptional regulator FOA56_01010 ENOG4106S2D Transcriptional regulator FOA56_01020 ENOG4105CA0 peroxidase FOA56_01025 ENOG4105CVK Glutamate decarboxylase FOA56_01030 ENOG4108NKV transcriptional regulator FOA56_01035 ENOG4105D3F AraC Family Transcriptional Regulator FOA56_01040 ENOG4105BZS acriflavin resistance protein FOA56_01045 ENOG4105C1P efflux transporter, rnd family, mfp subunit FOA56_01055 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci FOA56_01060 ENOG4108YK4 Acid-resistance membrane protein FOA56_01065 ENOG41060V2 Acid-resistance protein FOA56_01070 ENOG4105XXV Acid-resistance protein FOA56_01075 ENOG4105KT7 mgtC SapB transporter FOA56_01085 ENOG4105Y4Z Outer Membrane Lipoprotein FOA56_01105 ENOG4105K89 arsenate reductase FOA56_01110 ENOG4107R5R arsenical pump membrane protein FOA56_01115 ENOG4105KBH arsR family transcriptional regulator FOA56_01125 ENOG4105DC8 reductase FOA56_01130 ENOG4105D6S protein involved in catabolism of external DNA FOA56_01135 ENOG4105DGW oligopeptidase A FOA56_01140 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) FOA56_01145 ENOG4105DUX Transporter FOA56_01155 ENOG4108M6U Universal stress protein A FOA56_01165 ENOG4105CJ3 phosphate transporter FOA56_01170 ENOG4105CBX hi0933 family FOA56_01175 ENOG4107UNS conserved inner membrane protein FOA56_01190 ENOG4105D0S secretion protein (HlyD FOA56_01195 ENOG4105CJ1 ABC, transporter FOA56_01200 ENOG4105CMI transporter FOA56_01215 ENOG4105D2N Aldolase FOA56_01230 ENOG4105DT3 PTS system, galactitol-specific IIc component FOA56_01235 ENOG41090UW PTS System FOA56_01245 ENOG4105FDP GntR family transcriptional regulator FOA56_01260 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FOA56_01265 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOA56_01270 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOA56_01275 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FOA56_01280 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FOA56_01285 ENOG4105DSF transport protein FOA56_01290 ENOG4105F9N Major Facilitator Superfamily FOA56_01295 ENOG4108W1V Lipoprotein FOA56_01300 ENOG4105EX9 Membrane FOA56_01315 ENOG4107FS9 Membrane FOA56_01325 ENOG4105MG3 Membrane FOA56_01330 ENOG4106H78 methyltransferase FOA56_01335 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOA56_01340 ENOG4105CAK Cell division ATP-binding protein ftsE FOA56_01345 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOA56_01350 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOA56_01355 ENOG4105CP9 extracellular ligand-binding receptor FOA56_01360 ENOG4105U59 -acetyltransferase FOA56_01365 ENOG4105CP9 extracellular ligand-binding receptor FOA56_01370 ENOG4105C32 Amino acid ABC transporter (Permease) FOA56_01375 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FOA56_01380 ENOG4105C0Z ABC transporter FOA56_01385 ENOG4108IV0 ABC, transporter FOA56_01390 ENOG4105BZ7 extracellular solute-binding protein family 1 FOA56_01395 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FOA56_01400 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOA56_01410 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FOA56_01415 ENOG4105WC8 Conserved Protein FOA56_01420 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FOA56_01425 ENOG4106FA4 FOA56_01445 ENOG4105GMB type VI secretion system effector, hcp1 family FOA56_01450 ENOG4105WCN acetyltransferase FOA56_01455 ENOG4105D9R oxidoreductase FOA56_01460 ENOG4105C2I pirin domain protein FOA56_01465 ENOG4105DIQ Transcriptional regulator FOA56_01470 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FOA56_01475 ENOG4105C6Z Gluconate FOA56_01480 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FOA56_01485 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOA56_01510 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FOA56_01535 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOA56_01550 ENOG4105E98 transcriptional regulator DeoR family FOA56_01555 ENOG4105CYB regulatoR FOA56_01560 ENOG4105E0Y RtcB Protein FOA56_01575 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FOA56_01580 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FOA56_01585 ENOG4105C6Z Gluconate FOA56_01595 ENOG4105MJ2 Competence protein FOA56_01605 ENOG4105DNE Transposase FOA56_01615 ENOG4105CE1 Ferrous iron transport protein b FOA56_01620 ENOG4105XFK Ferrous iron transport protein A FOA56_01625 ENOG4105BZM domain protein FOA56_01630 ENOG4108RRZ Transcription elongation factor GreB FOA56_01635 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOA56_01640 ENOG4105E0F Histidine kinase FOA56_01660 ENOG4108MAJ Membrane FOA56_01670 ENOG4105VEJ Heat shock protein FOA56_01675 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FOA56_01680 ENOG4105DQY intracellular growth attenuator FOA56_01685 ENOG4107RK2 ADP-ribose diphosphatase NudE FOA56_01690 ENOG4108JQC penicillin-binding protein 1A FOA56_01695 ENOG4108U1Q Pilus assembly protein FOA56_01700 ENOG41065NF Fimbrial assembly family protein FOA56_01705 ENOG4105XPX DNA utilization protein HofO FOA56_01710 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FOA56_01715 ENOG4105E4G Type IV pilus FOA56_01730 ENOG4105EGB membrane protein DamX FOA56_01735 ENOG4105DFE Dna adenine methylase FOA56_01740 ENOG4105DJV ribulose-phosphate 3-epimerase FOA56_01750 ENOG4105C31 Tryptophanyl-tRNA synthetase FOA56_01755 ENOG4108M21 FOA56_01760 ENOG4105RMW regulation of transcription, DNA-dependent FOA56_01765 ENOG4108626 Racemase FOA56_01770 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FOA56_01775 ENOG41080QX K07048 phosphotriesterase-related protein FOA56_01780 ENOG4105MUZ Protein of unknown function DUF2620 FOA56_01785 ENOG4106M0N transport system permease protein FOA56_01790 ENOG4106PKC pyridoxal phosphate binding FOA56_01795 ENOG4105FDP GntR family transcriptional regulator FOA56_01800 ENOG4108KPW sugar kinase FOA56_01805 ENOG4107Y0V Not clear, may be involved in an isomerization step FOA56_01810 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FOA56_01815 ENOG4107QHQ amino acid FOA56_01820 ENOG4105VYH FOA56_01830 ENOG4107V9H nitrite transporter FOA56_01835 ENOG4105WZK nitrite reductase NADPH small subunit FOA56_01840 ENOG4107QZF nitrite reductase NADPH large subunit FOA56_01850 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FOA56_01855 ENOG4106195 uncharacterized protein yhfG FOA56_01860 ENOG4105MZU cell filamentation protein FOA56_01865 ENOG4105DDQ anthranilate synthase FOA56_01870 ENOG4105C8Y Acetylornithine aminotransferase FOA56_01875 ENOG410613R integral membrane protein, YccS YhfK family FOA56_01880 ENOG4107RYR Transcriptional regulator, Crp Fnr family FOA56_01885 ENOG4108UKZ OsmC family FOA56_01890 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FOA56_01900 ENOG4105DNZ Alpha Beta Hydrolase FOA56_01905 ENOG4105C5H ABC transporter FOA56_01920 ENOG4105VKU nucleicacid-binding protein FOA56_01925 ENOG4108YZY peptidylprolyl cis-trans isomerase FOA56_01935 ENOG4108V1T peptidylprolyl cis-trans isomerase FOA56_01940 ENOG4105WWK YheO domain protein FOA56_01980 ENOG4105W53 bacterioferritin-associated ferredoxin FOA56_01985 ENOG4108UQY Iron-storage protein FOA56_02005 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FOA56_02010 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FOA56_02020 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FOA56_02025 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FOA56_02030 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FOA56_02035 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FOA56_02045 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FOA56_02055 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FOA56_02070 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FOA56_02080 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FOA56_02085 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FOA56_02095 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FOA56_02100 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOA56_02105 ENOG41067V7 50S ribosomal protein L36 FOA56_02110 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FOA56_02120 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FOA56_02125 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FOA56_02135 ENOG4105VTS DnaJ-like, subfamily C FOA56_02140 ENOG4105W1Y Transcriptional regulator FOA56_02145 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FOA56_02155 ENOG4105C1A potassium transporter peripheral membrane FOA56_02175 ENOG4105C79 DNA protecting protein DprA FOA56_02185 ENOG4108WI1 Dna topoisomerase FOA56_02200 ENOG4105SG3 Protein of unknown function (DUF1488) FOA56_02205 ENOG4108Z0R Transferase FOA56_02245 ENOG4105CDA abc transporter atp-binding protein FOA56_02250 ENOG4105DRP amino acid AbC transporter FOA56_02255 ENOG4105EZ7 amino acid ABC transporter FOA56_02265 ENOG4105XCM membrane LIPOPROTEIN FOA56_02270 ENOG4105BZS acriflavin resistance protein FOA56_02275 ENOG4105C1P efflux transporter, rnd family, mfp subunit FOA56_02280 ENOG4108XG4 DNA-binding transcriptional regulator FOA56_02285 ENOG41061ME transport protein FOA56_02290 ENOG4105CEC DNA methylase N-4 N-6 FOA56_02295 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FOA56_02300 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOA56_02310 ENOG4108IA2 Sodium pantothenate symporter FOA56_02315 ENOG4105RG0 Membrane FOA56_02320 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOA56_02325 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FOA56_02330 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FOA56_02335 ENOG41062P1 Diguanylate cyclase phosphodiesterase FOA56_02340 ENOG4105DFF Rod shape-determining protein mreb FOA56_02345 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FOA56_02350 ENOG4105VQ7 Rod shape-determining protein MreD FOA56_02360 ENOG4105C03 ribonuclease FOA56_02365 ENOG4105QD6 exported protein FOA56_02370 ENOG4105D1U peptidase U62 modulator of DNA gyrase FOA56_02375 ENOG4105CR8 Transcriptional regulator FOA56_02395 ENOG4105UNR (Barnase) inhibitor FOA56_02400 ENOG4105RID UPF0379 protein yhcN FOA56_02415 ENOG4105C0H protease FOA56_02420 ENOG4105C0H protease FOA56_02425 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FOA56_02430 ENOG4105D6Z AFG1 family ATPase FOA56_02440 ENOG4108UJD 30S ribosomal protein S9 FOA56_02450 ENOG4107MKT Stringent starvation protein a FOA56_02455 ENOG4105KB2 stringent starvation protein b FOA56_02460 ENOG4105CEE C4-dicarboxylate transporter FOA56_02485 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) FOA56_02490 ENOG4108R66 Conserved Protein FOA56_02495 ENOG4105DFS Conserved Protein FOA56_02500 ENOG4105BZ8 glutamate synthase FOA56_02505 ENOG4105CBC glutamate synthase FOA56_02510 ENOG4105N5T Radical SAM Protein FOA56_02515 ENOG4105BZU Histidine kinase FOA56_02520 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FOA56_02530 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FOA56_02535 ENOG41080Z8 PHOSPHOCARRIER protein FOA56_02545 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FOA56_02550 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FOA56_02555 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOA56_02560 ENOG4108IUZ ABC transporter FOA56_02565 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FOA56_02570 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FOA56_02580 ENOG4105C2X Arabinose 5-phosphate isomerase FOA56_02585 ENOG4105FEU K -dependent Na -Ca exchanger FOA56_02590 ENOG4105DHJ ABC, transporter FOA56_02595 ENOG4105CY3 ABC transporter, permease FOA56_02600 ENOG4107PE3 Mammalian cell entry related domain protein FOA56_02605 ENOG4105E3I toluene tolerance FOA56_02610 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FOA56_02615 ENOG4105VFK BolA family FOA56_02625 ENOG4105HVQ Regulatory factor of maltose metabolism FOA56_02630 ENOG4105EAH synthase FOA56_02645 ENOG4105QYV Membrane FOA56_02655 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FOA56_02660 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FOA56_02665 ENOG4105HBR Rna-binding protein FOA56_02670 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FOA56_02675 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOA56_02680 ENOG4105EEI dihydropteroate synthase FOA56_02720 ENOG4105CHV Transcription elongation factor NusA FOA56_02735 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FOA56_02750 ENOG4105RT1 May be involved in cell division (By similarity) FOA56_02760 ENOG4105C1J atp-dependent rna helicase FOA56_02765 ENOG4105CIC tryptophan-specific transport protein FOA56_02770 ENOG4105DEN Luciferase family FOA56_02775 ENOG4106RZ4 Peptidase U32 FOA56_02780 ENOG4105CFP Peptidase U32 FOA56_02785 ENOG4105XPQ lipid carrier protein FOA56_02790 ENOG4108YYD acetyltransferase FOA56_02805 ENOG4107R7Y intracellular protease Pfpi family FOA56_02810 ENOG4105K4T epimerase FOA56_02815 ENOG4107S21 permease FOA56_02820 ENOG4105W4M Transport-associated protein FOA56_02840 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOA56_02845 ENOG4105I74 Fimbrial protein FOA56_02850 ENOG4105CW0 outer membrane usher protein FOA56_02855 ENOG4108VCD Chaperone FOA56_02860 ENOG4105Q10 Fimbrial-like protein FOA56_02865 ENOG4106HBN Galactosamine-6-phosphate isomerase FOA56_02870 ENOG4105F3R pts system mannose fructose sorbose family iid FOA56_02875 ENOG4105ETZ PTS System FOA56_02880 ENOG4108UZY PTS System FOA56_02890 ENOG4105E70 isomerase FOA56_02895 ENOG4105CE4 GlcNAc 6-P deacetylase FOA56_02900 ENOG4108YTN IIa component FOA56_02905 ENOG4105F3R pts system mannose fructose sorbose family iid FOA56_02915 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB FOA56_02925 ENOG4105E98 transcriptional regulator DeoR family FOA56_02930 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression FOA56_02935 ENOG4105ZEG Suppressor protein FOA56_02940 ENOG4105CTX dehydratase FOA56_02945 ENOG4105DJB Major Facilitator Superfamily FOA56_02955 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOA56_02960 ENOG4105BZW Glycerate kinase FOA56_02995 ENOG410811B TRANSCRIPTIONal FOA56_03000 ENOG4105C7B Threonine dehydratase FOA56_03010 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FOA56_03015 ENOG4105C6N Formate acetyltransferase FOA56_03020 ENOG4105KME endoribonuclease L-psp FOA56_03025 ENOG4105EJQ L-serine dehydratase FOA56_03030 ENOG4105C44 Serine transporter FOA56_03040 ENOG4106D80 Uncharacterized protein YhaL FOA56_03045 ENOG4108CNN domain protein FOA56_03050 ENOG4105CWB LysR family transcriptional Regulator FOA56_03055 ENOG4105KAF membrAne FOA56_03060 ENOG4105KAF membrAne FOA56_03065 ENOG4105CHF Glutathione S-transferase FOA56_03070 ENOG4108VBZ doxx family FOA56_03075 ENOG4105YJD FOA56_03080 ENOG41090KG Inner membrane protein YqjE FOA56_03085 ENOG4105NE1 Conserved Protein FOA56_03090 ENOG4105WAY exported protein FOA56_03095 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) FOA56_03100 ENOG4106W5V Membrane FOA56_03105 ENOG4107YCY Transcriptional regulator FOA56_03130 ENOG4105DPW Major facilitator superfamily MFS_1 FOA56_03140 ENOG4105CTX dehydratase FOA56_03145 ENOG4105P66 Membrane FOA56_03150 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FOA56_03155 ENOG4105DU1 integral membrane protein, terc FOA56_03160 ENOG4105EE0 oxidoreductase FOA56_03165 ENOG4108UB4 uncharacterized protein ygjQ FOA56_03170 ENOG4108VKG metal-dependent hydrolase FOA56_03185 ENOG4108Z3N Transcriptional regulator FOA56_03190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOA56_03195 ENOG4107WCA isomerase FOA56_03200 ENOG4107W6W Conserved Protein FOA56_03205 ENOG4105E5D amino acid FOA56_03210 ENOG4105FK9 beta-D-galactosidase beta subunit FOA56_03215 ENOG4105CNT hydrolase family 2 FOA56_03220 ENOG4105CQ4 Transcriptional regulator FOA56_03225 ENOG4108Y51 tRNA-binding protein FOA56_03235 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FOA56_03240 ENOG4105NTW Transcriptional regulator FOA56_03245 ENOG4105Q26 Siderophore-interacting protein FOA56_03260 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOA56_03265 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOA56_03270 ENOG4105VCC 30S ribosomal protein S21 FOA56_03280 ENOG4107QPK )-transporter FOA56_03285 ENOG4107GFK fumarate FOA56_03290 ENOG4106DSS Tartrate dehydratase subunit alpha FOA56_03295 ENOG4105EJC lysr family transcriptional regulator FOA56_03305 ENOG4107ZVW dihydroneopterin aldolase FOA56_03320 ENOG4106MWK domain protein FOA56_03325 ENOG4105I7R Adenylate cyclase FOA56_03350 ENOG4107S78 Band 7 protein FOA56_03355 ENOG4105PV3 Inner membrane protein yqiJ FOA56_03365 ENOG4108MY7 Fimbrial FOA56_03370 ENOG4108TTM chaperone FOA56_03380 ENOG4105H8W Fimbrial protein FOA56_03385 ENOG4105W0Z cytoplasmic protein FOA56_03400 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOA56_03405 ENOG4106032 Glutathionylspermidine synthase FOA56_03415 ENOG4105DFG type I secretion outer membrane protein FOA56_03420 ENOG41087AY ADP-Ribose pyrophosphatase FOA56_03425 ENOG4108SX3 cytoplasmic protein FOA56_03430 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FOA56_03435 ENOG4105IPS esterase FOA56_03440 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOA56_03445 ENOG4105VRH Antibiotic biosynthesis monooxygenase FOA56_03450 ENOG4105NF4 modulator of drug activity FOA56_03460 ENOG4105DHQ Histidine kinase FOA56_03465 ENOG4105XJC Two component transcriptional regulator (Winged helix family FOA56_03470 ENOG4105H4F exported protein FOA56_03475 ENOG4105F4I Transcriptional regulator FOA56_03480 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOA56_03485 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FOA56_03490 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FOA56_03495 ENOG4105CCT upf0313 protein FOA56_03505 ENOG4105ZKC Conserved Protein FOA56_03510 ENOG4105CV8 reductase FOA56_03515 ENOG4108I6A alcohol dehydrogenase FOA56_03520 ENOG4105CF7 AraC family transcriptional regulator FOA56_03525 ENOG4108K81 inner membrane protein YghB FOA56_03530 ENOG4105C28 cystathionine FOA56_03535 ENOG4105CWK Biopolymer transport protein, ExbB FOA56_03540 ENOG4108ZZF transport protein (ExbD) FOA56_03545 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FOA56_03555 ENOG4105CPC Aldo Keto reductase FOA56_03565 ENOG410900S Protein of unknown function (DUF2623) FOA56_03570 ENOG4105E3S small subunit FOA56_03575 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FOA56_03580 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FOA56_03585 ENOG4105DPX Hydrogenase, large subunit FOA56_03590 ENOG4108USZ hydrogenase FOA56_03595 ENOG4108WGS hydrogenase 2-specific chaperone FOA56_03600 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FOA56_03605 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FOA56_03620 ENOG4105CYM Glutathione S-transferase FOA56_03625 ENOG4106032 Glutathionylspermidine synthase FOA56_03630 ENOG4105CJ3 phosphate transporter FOA56_03635 ENOG4108GH0 ATP-binding protein yghT FOA56_03645 ENOG4106FPV ATP-binding protein YghR FOA56_03650 ENOG4108S55 polysaccharide biosynthesis protein FOA56_03660 ENOG4108UUE Transcriptional regulator FOA56_03665 ENOG4108M8S permease YjgP YjgQ family protein FOA56_03675 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FOA56_03680 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FOA56_03690 ENOG4107RCI amp-dependent synthetase and ligase FOA56_03700 ENOG4108KWP DNA-binding transcriptional regulator GlcC FOA56_03705 ENOG4105CQB FAD linked oxidase domain protein FOA56_03710 ENOG4105EU8 FAD linked oxidase domain protein FOA56_03715 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOA56_03720 ENOG4108ZJF Glcg protein FOA56_03725 ENOG4107QP3 malate synthase g FOA56_03730 ENOG4105DAA L-lactate FOA56_03735 ENOG4105F88 accessory colonization factor AcfD FOA56_03745 ENOG410765S (LipO)protein FOA56_03760 ENOG4107QHF type ii secretion system protein e FOA56_03765 ENOG4105D7Q type ii secretion system FOA56_03770 ENOG4108VAU general secretion pathway protein G FOA56_03780 ENOG4105X5Z General secretion pathway protein I FOA56_03800 ENOG4105U1E general secretion pathway protein M FOA56_03870 ENOG41083GP type iii secretion FOA56_03890 ENOG4108IUF type iii secretion FOA56_04115 ENOG4105E5H Transposase FOA56_04130 ENOG4108UQV Membrane FOA56_04135 ENOG4105CXN decarboxylase FOA56_04140 ENOG4105EAA nucleoside FOA56_04155 ENOG4105CEN a g-specific adenine glycosylase FOA56_04165 ENOG41090ED Protein with unknown function (DUF469) FOA56_04170 ENOG4105K33 Periplasmic Protein FOA56_04175 ENOG4105HDK L-asparaginase FOA56_04180 ENOG4106MH3 alpha helix chain FOA56_04185 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FOA56_04190 ENOG41069H7 transport system small permease component FOA56_04195 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FOA56_04200 ENOG4105CSA Coproporphyrinogen iii oxidase FOA56_04205 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FOA56_04215 ENOG4108VIA integral membrane protein FOA56_04220 ENOG4105DFA alanine racemase domain protein FOA56_04225 ENOG4105CZX twitching motility protein FOA56_04240 ENOG4105D7Z glutathione synthase FOA56_04245 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOA56_04250 ENOG4105RWS endonuclease I FOA56_04260 ENOG4107QNK )-transporter FOA56_04275 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FOA56_04290 ENOG4108K0D peptidase, M48 FOA56_04295 ENOG4105CV1 Transketolase (EC 2.2.1.1) FOA56_04300 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia FOA56_04305 ENOG4105CTS PTS system mannitol-specific FOA56_04310 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FOA56_04315 ENOG4108Q8A Fructose-1,6-bisphosphatase FOA56_04320 ENOG4108R4K DNA-binding, transcriptional regulator FOA56_04325 ENOG4107Z1W Fructose transport system kinase FOA56_04330 ENOG4108JJB ABC transporter FOA56_04335 ENOG4108JJB ABC transporter FOA56_04365 ENOG4105D2N Aldolase FOA56_04370 ENOG4105D64 Mechanosensitive ion channel FOA56_04375 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOA56_04380 ENOG4105MPN Membrane FOA56_04385 ENOG4105DEQ transcriptional regulator FOA56_04390 ENOG4105DEQ transcriptional regulator FOA56_04395 ENOG4105CYC Transferase FOA56_04400 ENOG4108M7F enoyl-CoA hydratase isomerase FOA56_04405 ENOG4105DJT lAO AO transport system ATPase FOA56_04410 ENOG4105D5P Methylmalonyl-coA mutase FOA56_04430 ENOG4108JQ1 Dehydrogenase FOA56_04445 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOA56_04465 ENOG4107RAQ aminopeptidase FOA56_04470 ENOG4105D0A hydroxylase FOA56_04475 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FOA56_04500 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FOA56_04505 ENOG4105CS2 ec 3.2.1.21 FOA56_04515 ENOG4108UT2 hemolysin iii FOA56_04535 ENOG4105Y75 tpr repeat protein FOA56_04540 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FOA56_04545 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FOA56_04550 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOA56_04555 ENOG4105T95 Thiol disulfide interChange protein FOA56_04560 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOA56_04570 ENOG4105CRK lysyL-tRNA synthetase FOA56_04590 ENOG4105C2W permease FOA56_04595 ENOG4105BZ8 glutamate synthase FOA56_04600 ENOG4108R8B oxidoreductase Fe-S subunit FOA56_04605 ENOG4105C7N Xanthine uracil vitamin C permease FOA56_04610 ENOG4107QUY Guanine deaminase FOA56_04615 ENOG4105C2W permease FOA56_04620 ENOG4105C7W Xanthine dehydrogenase FOA56_04625 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase FOA56_04630 ENOG4107UUR Chlorohydrolase aminohydrolase FOA56_04635 ENOG4105BZ8 glutamate synthase FOA56_04640 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase FOA56_04645 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC FOA56_04650 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FOA56_04655 ENOG4105C5B carbamate kinase FOA56_04665 ENOG4107S4Y M20 DapE family protein YgeY FOA56_04670 ENOG4107RCH Diaminopropionate ammonia-lyase FOA56_04675 ENOG4105IW6 Carbamoyltransferase FOA56_04680 ENOG4108JUB Transcriptional regulator FOA56_04685 ENOG4108UTP (2Fe-2S)-binding domain protein FOA56_04690 ENOG4108HR6 Dehydrogenase FOA56_04695 ENOG4105C7W Xanthine dehydrogenase FOA56_04700 ENOG4108K5P (LipO)protein FOA56_04710 ENOG4108T88 FOA56_04730 ENOG4108YAB Invasion protein FOA56_04755 ENOG4105FV3 FOA56_04760 ENOG4108TC1 Transcriptional regulator FOA56_04765 ENOG4105ISV protein with bipartite regulator domain FOA56_04770 ENOG4108MHD transport protein FOA56_04775 ENOG4105CHU acetyl-coa acetyltransferase FOA56_04785 ENOG4105CHR reductase FOA56_04790 ENOG4107QNK )-transporter FOA56_04800 ENOG4105RQF LysR family Transcriptional regulator FOA56_04805 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOA56_04810 ENOG41060NJ transcriptional regulator FOA56_04830 ENOG4105CPC Aldo Keto reductase FOA56_04835 ENOG4105SUV lipoprotein YgdR FOA56_04840 ENOG4105EE5 Membrane protein terC FOA56_04860 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FOA56_04875 ENOG4105IPU prepilin peptidase dependent protein A FOA56_04880 ENOG4105JCS prepilin peptidase dependent protein FOA56_04885 ENOG4105SEN Protein of unknown function (DUF2509) FOA56_04890 ENOG4105RVB Prepilin peptidase dependent protein c FOA56_04895 ENOG4105DSY exodeoxyribonuclease V, gamma FOA56_04900 ENOG4107QXK peptidase FOA56_04905 ENOG4107QKA exodeoxyribonuclease V beta FOA56_04910 ENOG4107QYX exodeoxyribonuclease v alpha FOA56_04915 ENOG4107QZM n-acetylglutamate synthase FOA56_04920 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOA56_04940 ENOG4105CA3 membrane-bound lytic murein transglycosylase FOA56_04945 ENOG4105CUZ uba thif-type nad fad binding protein FOA56_04950 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FOA56_04955 ENOG4105C9B Cysteine desulfurase FOA56_04960 ENOG4105M5B (LipO)protein FOA56_04965 ENOG4105ETT transcriptional Regulator, LysR family FOA56_04970 ENOG4105M08 Membrane FOA56_04980 ENOG4107EDW L-fucose operon activator FOA56_04990 ENOG4105CMG Carbohydrate kinase FOA56_05000 ENOG4105EDR glucose galactose transporter FOA56_05005 ENOG4107W7X Aldolase FOA56_05010 ENOG4105C0A alcohol dehydrogenase FOA56_05020 ENOG4105EJQ L-serine dehydratase FOA56_05025 ENOG4105C44 Serine transporter FOA56_05030 ENOG4105EWT decarboxylase family FOA56_05045 ENOG4105WP7 tRNA pseudouridine synthase C FOA56_05050 ENOG4105DR9 pseudouridine synthase FOA56_05055 ENOG4105QDK Flavodoxin FOA56_05060 ENOG4105DJB Major Facilitator Superfamily FOA56_05065 ENOG4105EQX glucarate dehydratase FOA56_05070 ENOG4105EQX glucarate dehydratase FOA56_05075 ENOG4105BZU Histidine kinase FOA56_05085 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOA56_05090 ENOG4106A2Z transcriptional regulator antitoxin, MazE FOA56_05095 ENOG4105MZG transcriptional modulator of maze toxin, mazf FOA56_05100 ENOG4105DXN mazG family FOA56_05120 ENOG4105HA9 of methanol dehydrogenase type FOA56_05130 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOA56_05140 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOA56_05165 ENOG4107635 Hok Gef family protein FOA56_05170 ENOG4105DTT CRISPR-associated helicase, cas3 FOA56_05175 ENOG4105CYR Crispr-associated protein, cse1 family FOA56_05185 ENOG41060M0 Crispr-associated protein, cse4 family FOA56_05190 ENOG4108VWQ crispr-associated protein FOA56_05200 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FOA56_05205 ENOG4105PWE CRISPR-associated protein cas2 FOA56_05210 ENOG4108MXK alkaline phosphatase isozyme conversion FOA56_05230 ENOG4105N0Z inner membrane protein ygbE FOA56_05265 ENOG4108K5P (LipO)protein FOA56_05270 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOA56_05280 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FOA56_05285 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FOA56_05290 ENOG4105KZM cytoplasmic protein FOA56_05295 ENOG4105C6Z Gluconate FOA56_05300 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FOA56_05305 ENOG4105FB2 class II Aldolase FOA56_05310 ENOG4105G63 Type III effector Hrp-dependent FOA56_05315 ENOG4105ZXK Dehydrogenase FOA56_05320 ENOG4105MVE transcriptional regulator FOA56_05325 ENOG4105MEW serine threonine protein phosphatase FOA56_05340 ENOG4105VXR cytoplasmic protein FOA56_05345 ENOG4108JUA Transcriptional regulator FOA56_05350 ENOG4105C45 hydrogenase expression formation protein (HypE) FOA56_05355 ENOG4105CQS hydrogenase expression formation protein HypD FOA56_05360 ENOG41083WG hydrogenase assembly chaperone FOA56_05365 ENOG4107RSS Hydrogenase accessory protein HypB FOA56_05370 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FOA56_05380 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FOA56_05385 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FOA56_05390 ENOG4107R30 NADH dehydrogenase FOA56_05395 ENOG4107TDF Formate hydrogenlyase subunit 4 FOA56_05400 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOA56_05405 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FOA56_05410 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FOA56_05415 ENOG4105I6X formate hydrogenlyase maturation FOA56_05420 ENOG4108MG9 hydrogenase 3 maturation protease FOA56_05430 ENOG4108Z3N Transcriptional regulator FOA56_05445 ENOG4105CS2 ec 3.2.1.21 FOA56_05450 ENOG4105C5Y PTS System FOA56_05455 ENOG4105DDV Transcriptional regulator (LacI family FOA56_05460 ENOG4108RC0 Electron transport protein FOA56_05465 ENOG4105C8H hydrogenase maturation protein Hypf FOA56_05485 ENOG4105C2X Arabinose 5-phosphate isomerase FOA56_05490 ENOG410804X Transcriptional regulator FOA56_05495 ENOG4105J92 DNA-binding transcriptional activator GutM FOA56_05500 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FOA56_05505 ENOG4105VI0 Pts system, glucitol sorbitol-specific FOA56_05510 ENOG4105DZY Pts system, glucitol sorbitol-specific FOA56_05515 ENOG410787A Pts system, glucitol sorbitol-specific FOA56_05520 ENOG4105CVE Lytic murein transglycosylase FOA56_05525 ENOG4107TH8 cina domain protein FOA56_05545 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FOA56_05575 ENOG4107VXZ Hydrolase FOA56_05580 ENOG4105W39 Membrane FOA56_05595 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOA56_05600 ENOG4105CW7 secretion protein, HlyD family FOA56_05605 ENOG4105NTK Transcriptional repressor Mpra FOA56_05610 ENOG4105ZED uncharacterized protein ygaH FOA56_05615 ENOG4108UMN azlc family FOA56_05630 ENOG4105GIJ Glycine betaine FOA56_05635 ENOG4108HQS Glycine betaine FOA56_05640 ENOG4108IJ7 Glycine betaine FOA56_05645 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOA56_05650 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOA56_05655 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOA56_05660 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FOA56_05665 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FOA56_05670 ENOG4108WMJ Protein of unknown function (DUF2002) FOA56_05675 ENOG4108RNS Exports L-alanine (By similarity) FOA56_05680 ENOG4108X73 DNA- binding protein FOA56_05685 ENOG4108V62 Rhodanese domain protein FOA56_05690 ENOG41080HT Transcriptional regulator, arsr family FOA56_05695 ENOG4105VPI YqaE family transport protein FOA56_05700 ENOG4109066 lysm domain bon superfamily protein FOA56_05705 ENOG4108PVQ transcriptional regulator FOA56_05710 ENOG4105C85 amino acid FOA56_05715 ENOG4108JPW Aminotransferase FOA56_05720 ENOG4105C26 Dehydrogenase FOA56_05725 ENOG4105D5U fad dependent oxidoreductase FOA56_05760 ENOG4105DFP Integrase FOA56_05775 ENOG4108Z1B Cyclase dehydrase FOA56_05780 ENOG4105VDB UPF0125 protein FOA56_05785 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FOA56_05790 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOA56_05805 ENOG4108JU6 CBS domain protein FOA56_05810 ENOG4106KVJ cytochrome C assembly protein FOA56_05815 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FOA56_05840 ENOG41090EK ompa motb domain protein FOA56_05845 ENOG4108KHX Diguanylate cyclase FOA56_05850 ENOG4108WS1 FOA56_05855 ENOG4105QP9 Protein of unknown function (DUF2799) FOA56_05860 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FOA56_05865 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FOA56_05870 ENOG4105CQC Prephenate dehydratase FOA56_05880 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FOA56_05885 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FOA56_05890 ENOG4105C34 Pseudouridine synthase FOA56_05895 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOA56_05900 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOA56_05925 ENOG4105CSH Transporter FOA56_05930 ENOG4105T42 (LipO)protein FOA56_05935 ENOG4105JIM Phosphatidylserine synthase FOA56_05940 ENOG4105CD5 CoA-binding domain protein FOA56_05945 ENOG4106IUH DTW domain containing protein FOA56_05950 ENOG4105K63 Thioredoxin FOA56_05955 ENOG4105EIB trna rrna methyltransferase FOA56_05975 ENOG41090KR LysR family transcriptional Regulator FOA56_05980 ENOG4105C1J atp-dependent rna helicase FOA56_05990 ENOG4108IYU L-aspartate oxidase FOA56_06000 ENOG4105EMN RNA polymerase sigma factor FOA56_06005 ENOG41069PW sigma-e factor negative regulatory protein FOA56_06010 ENOG4105VQK sigma E regulatory protein, MucB RseB FOA56_06015 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FOA56_06025 ENOG4105C3F Signal peptidase i FOA56_06045 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FOA56_06060 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FOA56_06065 ENOG4106G6Q Transcriptional regulator FOA56_06070 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FOA56_06075 ENOG4108Z6B deaminase FOA56_06085 ENOG4107QIK phosphoribosylformylglycinamidine synthase FOA56_06090 ENOG4107WP9 Histidine kinase FOA56_06095 ENOG4108SKK alpha helix protein FOA56_06100 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOA56_06105 ENOG4108YZA Nitrogen regulatory protein pii FOA56_06110 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FOA56_06120 ENOG4108NZE NAGC-like transcriptional regulator FOA56_06125 ENOG4107HQ7 repeat protein FOA56_06130 ENOG4105FCA ABC transporter periplasmic-binding protein YphF FOA56_06135 ENOG4108F37 ATP-binding component of a transport system FOA56_06140 ENOG4105CNN ABC, transporter FOA56_06145 ENOG4105CPQ Dehydrogenase FOA56_06150 ENOG4108ZKT aldose 1-epimerase FOA56_06155 ENOG4108SB3 DoxX Family FOA56_06180 ENOG4105FUY alpha subunit FOA56_06185 ENOG4108W5M transcriptional regulator FOA56_06190 ENOG4105D8G Major Facilitator superfamily FOA56_06195 ENOG4108MN2 Stationary phase inducible protein CsiE FOA56_06200 ENOG4107XM9 (LipO)protein FOA56_06210 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FOA56_06225 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FOA56_06245 ENOG4108ZIT Ferredoxin, 2FE-2S FOA56_06250 ENOG4105WVQ Fe-S assembly protein IscX FOA56_06260 ENOG4105YYA enhanced serine sensitivity protein SseB FOA56_06265 ENOG4105KHC sulfurtransferase FOA56_06270 ENOG4105DN3 alpha-2-macroglobulin domain protein FOA56_06275 ENOG4108JQB penicillin-binding protein 1C FOA56_06305 ENOG4105N21 Membrane FOA56_06320 ENOG4105VPD cellular component movement FOA56_06330 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOA56_06340 ENOG41066DY Membrane FOA56_06345 ENOG4108ZMA Outer membrane lipoprotein FOA56_06350 ENOG41062G3 Protein of unknown function (DUF2633) FOA56_06355 ENOG4105BZU Histidine kinase FOA56_06360 ENOG4105C9X ppx gppa phosphatase FOA56_06365 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOA56_06370 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOA56_06385 ENOG4105C2W permease FOA56_06395 ENOG4105K89 arsenate reductase FOA56_06400 ENOG4105ERG peptidase m48, ste24p FOA56_06405 ENOG4105C02 permease FOA56_06410 ENOG4105TMB Formate nitrite transporter FOA56_06415 ENOG4108JUA Transcriptional regulator FOA56_06420 ENOG4105I6X formate hydrogenlyase maturation FOA56_06425 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FOA56_06435 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOA56_06440 ENOG4108JPZ Monovalent cation H antiporter subunit D FOA56_06445 ENOG4107WQX hydrogenase 4 membrane subunit FOA56_06455 ENOG4105D65 subunit l FOA56_06460 ENOG4107TDF Formate hydrogenlyase subunit 4 FOA56_06470 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FOA56_06475 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOA56_06480 ENOG4105RH4 Glycine cleavage system transcriptional repressor FOA56_06490 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FOA56_06505 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FOA56_06510 ENOG4105CGZ zinc metallopeptidase FOA56_06515 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) FOA56_06520 ENOG4106KED esterase YpfH FOA56_06535 ENOG4105KUZ arsenate reductase FOA56_06550 ENOG4105BZS acriflavin resistance protein FOA56_06555 ENOG4105BZU Histidine kinase FOA56_06560 ENOG4105BZ8 glutamate synthase FOA56_06570 ENOG4108PVD exported protein FOA56_06575 ENOG4105CV1 Transketolase (EC 2.2.1.1) FOA56_06580 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOA56_06585 ENOG4105C6K Malic enzyme FOA56_06590 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FOA56_06595 ENOG4106S4J ethanolamine utilization protein EutP FOA56_06600 ENOG4105NDK ethanolamine utilization protein FOA56_06605 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FOA56_06610 ENOG4107WUY phosphate acetyltransferase FOA56_06615 ENOG4105KNY Microcompartments protein FOA56_06620 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FOA56_06625 ENOG4108EKI Dehydrogenase FOA56_06630 ENOG4107RWI ethanolamine utilization protein eutJ FOA56_06635 ENOG4105C0A alcohol dehydrogenase FOA56_06640 ENOG4105ENY Ethanolamine utilization protein eutH FOA56_06645 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FOA56_06650 ENOG4105CPD ethanolamine ammonia-lyase FOA56_06660 ENOG4106D67 ethanolamine utilization protein FOA56_06665 ENOG4108X49 Ethanolamine utilization protein EutK FOA56_06670 ENOG4108K3Z AraC family transcriptional regulator FOA56_06680 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FOA56_06685 ENOG4108R6G acetyltransferase FOA56_06690 ENOG4105QZU Inner membrane protein YfeZ FOA56_06695 ENOG4105E7K (LipO)protein FOA56_06700 ENOG4105EZR dyp-type peroxidase family protein FOA56_06705 ENOG4107S1E Beta-lactamase FOA56_06710 ENOG4105C5Y PTS System FOA56_06725 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FOA56_06730 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FOA56_06735 ENOG4108I5D sulfate abc transporter FOA56_06740 ENOG4105ECW sulfate abc transporter FOA56_06745 ENOG4108IJ6 ABC transporter FOA56_06750 ENOG4105C6T cysteine synthase FOA56_06755 ENOG4105M0Y FOA56_06765 ENOG4105C5Y PTS System FOA56_06770 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOA56_06775 ENOG4105KZ7 phosphocarrier protein hpr FOA56_06780 ENOG4105C6T cysteine synthase FOA56_06800 ENOG4105VRT cytoplasmic protein FOA56_06805 ENOG4105DHU Bile acid FOA56_06810 ENOG4108M0I Transcriptional regulator FOA56_06850 ENOG4105GXM Putative transcription regulator (DUF1323) FOA56_06855 ENOG4105HZG regulatoR FOA56_06870 ENOG4108KMM Diguanylate cyclase FOA56_06875 ENOG4105D9N nucleoside FOA56_06885 ENOG4109076 Conserved Protein FOA56_06890 ENOG4105VCT ion-transport protein YfeO FOA56_06900 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FOA56_06905 ENOG410863U PTS System FOA56_06910 ENOG4105DC7 peptidase M24 FOA56_06915 ENOG4105CN9 Peptidase m42 family protein FOA56_06920 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOA56_06925 ENOG4108CIP transcriptional regulator FOA56_06930 ENOG4105DY9 regulatoR FOA56_06935 ENOG4108HRK Histidine kinase FOA56_06940 ENOG4105CHM Aminotransferase FOA56_06950 ENOG4105D1S lipid A biosynthesis FOA56_06955 ENOG4105W9M Membrane FOA56_06965 ENOG4108V08 YfdX protein FOA56_06980 ENOG4108N2Y auxin Efflux FOA56_06985 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FOA56_06990 ENOG4105BZU Histidine kinase FOA56_06995 ENOG4108WQH regulatoR FOA56_07000 ENOG4105CW7 secretion protein, HlyD family FOA56_07005 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOA56_07020 ENOG4106NDP Transcriptional regulator FOA56_07025 ENOG4108HKT sucrose-6-phosphate hydrolase FOA56_07030 ENOG4105D7K pfkb domain protein FOA56_07035 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FOA56_07045 ENOG4105S64 Formate nitrite transporter FOA56_07050 ENOG410903C (LipO)protein FOA56_07060 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FOA56_07065 ENOG4105KZW UPF0381 protein FOA56_07080 ENOG4108BY2 phosphohistidine phosphatase FOA56_07090 ENOG4106PG1 outer membrane usher protein FOA56_07095 ENOG4108FZ9 Chaperone FOA56_07100 ENOG4105NEV Fimbrial FOA56_07110 ENOG4105UGQ Fimbrial FOA56_07115 ENOG4105US4 fimbrial-like protein yfcP FOA56_07145 ENOG4105EJ9 Membrane FOA56_07150 ENOG4108BPE -transporting atpase FOA56_07155 ENOG4105MH2 YfcL protein FOA56_07160 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FOA56_07165 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOA56_07170 ENOG4105F9N Major Facilitator Superfamily FOA56_07175 ENOG4106WZ1 flagella biosynthesis regulator FOA56_07185 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOA56_07195 ENOG4105DQR SNARE associated Golgi FOA56_07205 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOA56_07210 ENOG4108S3P Sporulation domain protein FOA56_07215 ENOG4105E96 Colicin v production protein FOA56_07220 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FOA56_07225 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FOA56_07230 ENOG4105E89 ABC transporter FOA56_07235 ENOG4105E89 ABC transporter FOA56_07240 ENOG4105DSP amino acid AbC transporter FOA56_07245 ENOG4106YG3 ABC transporter FOA56_07250 ENOG4108JEH abc transporter atp-binding protein FOA56_07255 ENOG4105DNE Transposase FOA56_07260 ENOG4105ECP epimerase FOA56_07265 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase FOA56_07270 ENOG4105CYM Glutathione S-transferase FOA56_07275 ENOG4108SHQ Glutathione S-transferase FOA56_07280 ENOG4108RE9 Phosphodiesterase FOA56_07285 ENOG4105PTV Nudix Hydrolase FOA56_07295 ENOG4105C6K Malic enzyme FOA56_07300 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FOA56_07315 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FOA56_07320 ENOG4107QWE )-transporter FOA56_07330 ENOG4105CHM Aminotransferase FOA56_07335 ENOG4107NQ8 LysR family Transcriptional regulator FOA56_07355 ENOG4105GKE subunit e FOA56_07360 ENOG4107QIZ NADH dehydrogenase FOA56_07365 ENOG4108IEH NADH dehydrogenase subunit g FOA56_07375 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOA56_07380 ENOG4107UFS subunit j FOA56_07385 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOA56_07390 ENOG4105D65 subunit l FOA56_07395 ENOG4105C8S subunit m FOA56_07405 ENOG4105GDX Domain of unknown function (DUF1877) FOA56_07430 ENOG4107YB6 acetyltransferase, (GNAT) family FOA56_07435 ENOG4105TNS Conserved Protein FOA56_07440 ENOG4105E4F Isochorismate synthase FOA56_07455 ENOG4108IPT Naphthoate synthase FOA56_07465 ENOG4105CEY Amp-dependent synthetase and ligase FOA56_07470 ENOG4106GZG polymyxin resistance protein B FOA56_07520 ENOG4108UII YfaZ family FOA56_07530 ENOG4105CNV Aldolase FOA56_07535 ENOG4105DNE Transposase FOA56_07540 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOA56_07550 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FOA56_07555 ENOG4105CXY transporter FOA56_07560 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FOA56_07570 ENOG4105FQR PH-inducible protein involved in stress response FOA56_07575 ENOG4105XPH Ferredoxin FOA56_07580 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOA56_07585 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOA56_07590 ENOG4107GHC outer membrane autotransporter FOA56_07600 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOA56_07605 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) FOA56_07610 ENOG4108QJJ Protein of unknown function (DUF1175) FOA56_07615 ENOG4107S52 alpha-2-macroglobulin domain protein FOA56_07620 ENOG41081SK signal peptide protein FOA56_07625 ENOG4105EDV vault protein FOA56_07630 ENOG4105BZU Histidine kinase FOA56_07635 ENOG41068CG regulatoR FOA56_07640 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FOA56_07645 ENOG4105FCK Membrane FOA56_07650 ENOG4105CJ2 (LipO)protein FOA56_07655 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOA56_07660 ENOG4105CF1 Alkylated DNA repair protein FOA56_07665 ENOG4105IBP Cyclic peptide transporter FOA56_07680 ENOG4108ZNS ferredoxin-type protein NapF FOA56_07685 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FOA56_07695 ENOG4108BGM Quinol dehydrogenase periplasmic component FOA56_07700 ENOG4105GXZ Ferredoxin-type protein NapH FOA56_07705 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FOA56_07710 ENOG4105CUW cytochrome C-TYPE protein FOA56_07715 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FOA56_07720 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FOA56_07725 ENOG41060IM Heme exporter protein FOA56_07730 ENOG4105X3C heme exporter protein FOA56_07740 ENOG4105DA4 cytochrome c-type biogenesis protein FOA56_07745 ENOG4107QX9 Thiol disulfide interChange protein FOA56_07750 ENOG4105KWW Biogenesis protein FOA56_07755 ENOG4105WH1 Two component transcriptional regulator luxr family FOA56_07770 ENOG4105E68 Sulfatase FOA56_07790 ENOG4105CFI type iii restriction protein res subunit FOA56_07795 ENOG4105I08 Pseudouridine synthase FOA56_07800 ENOG4105C2C drug resistance transporter, Bcr CflA FOA56_07805 ENOG4105HG6 FOA56_07810 ENOG4108JQ5 ABC transporter FOA56_07815 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FOA56_07820 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FOA56_07825 ENOG4105E43 Extracellular solute-binding protein, family 5 FOA56_07830 ENOG4105CXC rtn protein FOA56_07835 ENOG4107TT5 NLP P60 protein FOA56_07840 ENOG41076MN Phosphoesterase, PA-phosphatase related FOA56_07845 ENOG4105CKI cobalamin synthesis protein FOA56_07850 ENOG4105DEI Mannitol dehydrogenase FOA56_07860 ENOG4105KRS Proteinase inhibitor FOA56_07865 ENOG4105S8Q sugar efflux transporter FOA56_07870 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FOA56_07875 ENOG4105DE4 1-phosphofructokinase FOA56_07880 ENOG4105DM4 PTS System FOA56_07885 ENOG4105DD7 kinase (PfkB family FOA56_07890 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FOA56_07895 ENOG4105D9N nucleoside FOA56_07900 ENOG4108Y4K DNA-binding transcriptional activator FOA56_07910 ENOG4105D9N nucleoside FOA56_07915 ENOG4105DD7 kinase (PfkB family FOA56_07925 ENOG4105HMI Membrane FOA56_07930 ENOG4105DUM transcriptional regulator, lysR family FOA56_07935 ENOG4108IQI permease FOA56_07940 ENOG4105D05 Receptor FOA56_07945 ENOG4105C4W S-formylglutathione hydrolase FOA56_07955 ENOG4105DHF Membrane FOA56_07960 ENOG41060NJ transcriptional regulator FOA56_07965 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FOA56_07970 ENOG4105C2J ABC transporter FOA56_07975 ENOG4108HWV )-transporter FOA56_07980 ENOG4107SJI Dehydrogenase FOA56_07985 ENOG4105BZ8 glutamate synthase FOA56_07990 ENOG4105Y9N Membrane FOA56_07995 ENOG4107GZ4 SanA protein FOA56_08005 ENOG41067MG lrgb family FOA56_08015 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FOA56_08025 ENOG4105ETP RND efflux system, outer membrane lipoprotein FOA56_08030 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FOA56_08035 ENOG4105KHU inner membrane protein YohD FOA56_08040 ENOG41069YE inner membrane protein yohC FOA56_08045 ENOG41061WM D-Alanyl-D-Alanine FOA56_08050 ENOG4105CXG d-lactate dehydrogenase FOA56_08055 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FOA56_08060 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FOA56_08065 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FOA56_08070 ENOG4108IJ8 ABC transporter FOA56_08075 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FOA56_08085 ENOG4108XDN Transcriptional regulator FOA56_08090 ENOG4108HRK Histidine kinase FOA56_08095 ENOG4108NEV two component transcriptional regulator, LytTR family FOA56_08100 ENOG4108W15 Protein of unknown function (DUF1456) FOA56_08105 ENOG4108YCW (LipO)protein FOA56_08110 ENOG410903U zinc ion binding FOA56_08115 ENOG4105DEG Vwa containing coxe family protein FOA56_08120 ENOG4105RD5 FOA56_08125 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FOA56_08135 ENOG4108KDT Molybdate metabolism regulator FOA56_08140 ENOG4108KDT Molybdate metabolism regulator FOA56_08150 ENOG4105D1F ATP-binding protein FOA56_08155 ENOG41067AK Protein of unknown function (DUF2574) FOA56_08160 ENOG41063W2 Fimbrial protein FOA56_08165 ENOG4108MQF Chaperone FOA56_08170 ENOG4105CW0 outer membrane usher protein FOA56_08175 ENOG410662B Type-1 fimbrial protein FOA56_08180 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FOA56_08200 ENOG4105DWF phosphomethylpyrimidine kinase FOA56_08205 ENOG4108UQ1 hydrolase, family 25 FOA56_08210 ENOG4105FDP GntR family transcriptional regulator FOA56_08215 ENOG4108TFM Kinase, PfkB family FOA56_08220 ENOG4108KD5 ADP-ribosylation crystallin J1 FOA56_08225 ENOG4105EAA nucleoside FOA56_08230 ENOG4105EIE fructose-bisphosphate aldolase FOA56_08250 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FOA56_08255 ENOG41090UW PTS System FOA56_08260 ENOG4105DT3 PTS system, galactitol-specific IIc component FOA56_08265 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FOA56_08280 ENOG41076Z6 Uncharacterized protein yegR FOA56_08285 ENOG4105CFP Peptidase U32 FOA56_08295 ENOG4105X54 addiction module antidote protein FOA56_08305 ENOG4105E3W Two component transcriptional regulator (Winged helix family FOA56_08310 ENOG4105EB3 Histidine kinase FOA56_08335 ENOG4108I1J Integrase FOA56_08345 ENOG4105XB7 anti-repressor protein FOA56_08510 ENOG4108R1E Serine threonine protein phosphatase 1 FOA56_08535 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_08540 ENOG4105KUS lysozyme FOA56_08550 ENOG4106050 phage regulatory protein, rha family FOA56_08555 ENOG4106YSC FOA56_08560 ENOG4105FKG DNA packaging protein FOA56_08565 ENOG4105UZW Tail fiber assembly protein FOA56_08570 ENOG4107DE1 head-to-tail joining protein FOA56_08580 ENOG4105F7J membrane-bound serine protease FOA56_08590 ENOG4105IM0 capsid protein FOA56_08665 ENOG4108X9F tail fiber protein FOA56_08705 ENOG4108M24 von Willebrand factor, type A FOA56_08710 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase FOA56_08715 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding FOA56_08720 ENOG4105R8A Heat shock protein FOA56_08725 ENOG4105D03 DNA-3-methyladenine glycosylase II FOA56_08730 ENOG4105BZU Histidine kinase FOA56_08735 ENOG4105DBI uridine monophosphokinase FOA56_08745 ENOG4108GAE asmA family FOA56_08750 ENOG4105EE5 Membrane protein terC FOA56_08755 ENOG4105DAY polysaccharide export protein FOA56_08760 ENOG4105KJF protein tyrosine phosphatase FOA56_08765 ENOG4105D75 Capsular exopolysaccharide family FOA56_08770 ENOG41090RK glycosyl transferase FOA56_08775 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB FOA56_08780 ENOG4107RXY Glycosyl transferase FOA56_08785 ENOG4108NYJ Colanic acid FOA56_08790 ENOG4105ECJ Glycosyl Transferase FOA56_08795 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FOA56_08800 ENOG4105C0K Gdp-mannose 4,6-dehydratase FOA56_08805 ENOG4105C30 Nad-dependent epimerase dehydratase FOA56_08810 ENOG4105FGF GDP-mannose mannosyl hydrolase FOA56_08815 ENOG4106CD9 glycosyl transferase group 1 FOA56_08820 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FOA56_08825 ENOG4107QKV phosphomannomutase FOA56_08830 ENOG4105D3Q Sugar transferase FOA56_08835 ENOG4105PSV Polysaccharide Biosynthesis Protein FOA56_08840 ENOG4105C74 pyruvyl transferase FOA56_08845 ENOG4107T8Q Glycosyl transferase (Group 1 FOA56_08850 ENOG4105G1A colanic acid biosynthesis protein FOA56_08855 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOA56_08860 ENOG4105C1B dTDP-glucose 4-6-dehydratase FOA56_08865 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOA56_08910 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOA56_08925 ENOG4105D7W serine acetyltransferase FOA56_08930 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOA56_08935 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOA56_08940 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) FOA56_08945 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FOA56_08960 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FOA56_08965 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FOA56_08975 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FOA56_08990 ENOG4105VTW prevent-host-death family FOA56_08995 ENOG4105KRQ Addiction module toxin, Txe YoeB family FOA56_09000 ENOG4108535 NAD dependent epimerase/dehydratase family FOA56_09005 ENOG4105EQ1 Transcriptional regulator FOA56_09015 ENOG4105CUB amino acid FOA56_09020 ENOG4105CUC YeeE YedE family protein FOA56_09030 ENOG4105CJB Exodeoxyribonuclease I FOA56_09035 ENOG4105DZ1 carboxypeptidase FOA56_09040 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FOA56_09075 ENOG4108YZT Adenosylcobinamide kinase FOA56_09090 ENOG4108PXI ErfK YbiS YcfS YnhG FOA56_09100 ENOG4106P55 Transcriptional regulator FOA56_09105 ENOG4107R11 Transcriptional regulator FOA56_09125 ENOG4105CDY transcriptional regulatory protein FOA56_09130 ENOG4105FYV Amp nucleosidase FOA56_09135 ENOG4105CSH Transporter FOA56_09170 ENOG4105HVQ Regulatory factor of maltose metabolism FOA56_09185 ENOG4105CNA YD repeat protein FOA56_09205 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) FOA56_09255 ENOG41087BU transcriptional repressor DicA FOA56_09315 ENOG4105WI6 cell killing protein encoded within cryptic prophage FOA56_09330 ENOG4108MXB Protein of unknown function (DUF968) FOA56_09335 ENOG4105KSK (crossover) junction endodeoxyribonuclease FOA56_09380 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_09425 ENOG4106YSC FOA56_09435 ENOG4105UZW Tail fiber assembly protein FOA56_09460 ENOG4105IM0 capsid protein FOA56_09530 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOA56_09540 ENOG4105H38 Membrane FOA56_09545 ENOG4108X9F tail fiber protein FOA56_09565 ENOG4105UZW Tail fiber assembly protein FOA56_09575 ENOG4106N4H Non-LEE-encoded type III effector F FOA56_09590 ENOG4108VKM cytochrome b561 FOA56_09595 ENOG4108MEK Metal-binding protein YodA FOA56_09610 ENOG4105VT2 5-hydroxyisourate hydrolase FOA56_09615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOA56_09620 ENOG4107ZY3 Histidine kinase FOA56_09635 ENOG4105FCK Membrane FOA56_09640 ENOG4105Y0K Inner membrane protein YedR FOA56_09645 ENOG4105EST Metal Dependent Phosphohydrolase FOA56_09650 ENOG4105DVF Cytosine-specific methyltransferase FOA56_09655 ENOG41090BB DNA mismatch endonuclease (vsr) FOA56_09660 ENOG4105FDR Membrane FOA56_09665 ENOG4105CKW Inner membrane protein yedI FOA56_09670 ENOG4105VNZ cytoplasmic protein FOA56_09675 ENOG4105BZU Histidine kinase FOA56_09685 ENOG4105YX3 cellular response to acidity FOA56_09700 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FOA56_09705 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FOA56_09710 ENOG4105VS8 Flagellar biosynthetic protein fliq FOA56_09715 ENOG4105CN7 Flagellar biosynthetic protein FliP FOA56_09720 ENOG4105K0P flagellar biosynthesis protein FOA56_09725 ENOG4105DD5 Flagellar motor switch protein FOA56_09730 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOA56_09735 ENOG4107ZI8 flagellar basal body-associated protein flil FOA56_09740 ENOG4105WF4 Flagellar hook-length control protein FOA56_09745 ENOG4105GSA Flagellar export protein flij FOA56_09750 ENOG4108JIR Flagellum-specific ATP synthase FOA56_09755 ENOG41090PJ Flagellar assembly protein FOA56_09760 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOA56_09765 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FOA56_09780 ENOG4108RAV Conserved protein FOA56_09785 ENOG4105KSU Redox protein FOA56_09790 ENOG41066VF YeeE YedE family protein FOA56_09795 ENOG4108W9D (LipO)protein FOA56_09800 ENOG4105E5K Alpha-amylase FOA56_09805 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) FOA56_09810 ENOG4105MQ3 flagellar protein FliS FOA56_09815 ENOG4105DTS flagellar hook-associated FOA56_09825 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOA56_09830 ENOG4108M9K flagella biosynthesis protein FliZ FOA56_09835 ENOG4105EAB amino acid AbC transporter FOA56_09845 ENOG4105E5Q amino acid AbC transporter FOA56_09850 ENOG4105CDA abc transporter atp-binding protein FOA56_09855 ENOG4105VJY transcriptional regulator FOA56_09860 ENOG4105XVG cytoplasmic protein FOA56_09870 ENOG4105WH1 Two component transcriptional regulator luxr family FOA56_09880 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOA56_09900 ENOG4106RHG Yeca family FOA56_09905 ENOG4105E0U tyrosine-specific transport protein FOA56_09910 ENOG4105VVZ metal-binding protein FOA56_09915 ENOG41090A1 ferritin FOA56_09920 ENOG4105P23 (LipO)protein FOA56_09930 ENOG4105N4N Protein of unknown function (DUF2766) FOA56_09935 ENOG4108UEC Ferritin-like protein FOA56_09940 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator FOA56_09945 ENOG4105C2J ABC transporter FOA56_09950 ENOG4105CNN ABC, transporter FOA56_09955 ENOG4108K4C ec 3.1.3.12 FOA56_09965 ENOG4108VA4 Universal stress protein FOA56_09975 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FOA56_09980 ENOG4107RD7 Flagellar Motor Protein, MotA FOA56_09985 ENOG4105ER2 Ompa motb domain protein FOA56_09990 ENOG4105CBS Chea signal transduction histidine kinase FOA56_09995 ENOG4108V3W Chemotaxis protein, CheW FOA56_10000 ENOG4105C8Q Methyl-accepting chemotaxis FOA56_10005 ENOG4105C8Q Methyl-accepting chemotaxis FOA56_10010 ENOG4105BZU Histidine kinase FOA56_10015 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FOA56_10020 ENOG4108VYJ response regulator receiver protein FOA56_10025 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FOA56_10030 ENOG4105D00 flagellar biosynthetic protein flhB FOA56_10035 ENOG4105D7B Flagellar biosynthesis protein flha FOA56_10040 ENOG4105W13 flagellar protein FOA56_10055 ENOG4106ZCM YecM protein FOA56_10065 ENOG4105CUW cytochrome C-TYPE protein FOA56_10070 ENOG4107QY8 reductase FOA56_10095 ENOG4105WJG Glutathione FOA56_10100 ENOG41081XQ Conserved Protein FOA56_10105 ENOG4105D3W isochorismatase FOA56_10115 ENOG4108TIT dATP pyrophosphohydrolase FOA56_10120 ENOG4105CDY transcriptional regulatory protein FOA56_10130 ENOG4107S01 Repressor protein MetJ FOA56_10150 ENOG4105FAV ABC, transporter FOA56_10155 ENOG4105FDK ABC transporter FOA56_10160 ENOG4105NXV High-affinity zinc uptake system protein FOA56_10165 ENOG4105DR5 peptidase FOA56_10170 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FOA56_10200 ENOG4108IJ9 (ABC) transporter FOA56_10210 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FOA56_10220 ENOG4107FKK extracellular solute-binding protein family 1 FOA56_10225 ENOG4105D56 permease protein FOA56_10260 ENOG4105CA9 Pyruvate kinase FOA56_10265 ENOG4106KNT transcriptional regulator FOA56_10270 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOA56_10275 ENOG4105C01 Dihydroxy-acid dehydratase FOA56_10280 ENOG4108UHU Aldolase FOA56_10290 ENOG4105X2V dna damage-inducible protein FOA56_10295 ENOG4105RSZ secreted protein FOA56_10300 ENOG4108Q2J Inner membrane protein YebE FOA56_10305 ENOG4105CUG Oligopeptidase b FOA56_10310 ENOG4105UMD exodeoxyribonuclease X FOA56_10315 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOA56_10320 ENOG4105MPK DNA polymerase III subunit theta FOA56_10325 ENOG4105FXM Copper resistance protein FOA56_10330 ENOG4108PNC copper resistance FOA56_10335 ENOG4105NKT exported protein FOA56_10345 ENOG4105UVW uncharacterized protein yebW FOA56_10350 ENOG4105WT8 Protein of unknown function (DUF1480) FOA56_10360 ENOG4105DY2 Paraquat-inducible protein b FOA56_10365 ENOG4105H2K paraquat-inducible protein a FOA56_10370 ENOG4108ZGC gaf domain protein FOA56_10380 ENOG4105CN1 protease FOA56_10390 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOA56_10395 ENOG4105J4Q Transcriptional regulator FOA56_10400 ENOG4105TIK FOA56_10410 ENOG4105Q3Y exported protein FOA56_10415 ENOG410610J Protein of unknown function (DUF2627) FOA56_10420 ENOG4105VEQ Cold shock protein FOA56_10425 ENOG4105DHI Methyltransferase FOA56_10440 ENOG4105F3R pts system mannose fructose sorbose family iid FOA56_10445 ENOG4105ETZ PTS System FOA56_10450 ENOG4108EQA pts system FOA56_10455 ENOG4105EE5 Membrane protein terC FOA56_10460 ENOG4107XTP (EAL) domain protein FOA56_10465 ENOG4105EJQ L-serine dehydratase FOA56_10475 ENOG4105CRQ synthase (Component I) FOA56_10485 ENOG4105V2F Uncharacterized protein yoac FOA56_10490 ENOG4105M4H endoribonuclease L-psp FOA56_10495 ENOG4105DVT helicase FOA56_10500 ENOG41072GX Peptidase M22 Glycoprotease FOA56_10505 ENOG4105Y4Z Outer Membrane Lipoprotein FOA56_10510 ENOG4105CEY Amp-dependent synthetase and ligase FOA56_10515 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FOA56_10520 ENOG4105E3J oxidoreductase FOA56_10525 ENOG4105DVW rieske (2Fe-2S) FOA56_10530 ENOG4105C94 Transporter FOA56_10535 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FOA56_10540 ENOG4105EJC lysr family transcriptional regulator FOA56_10550 ENOG4108RS6 transposase FOA56_10555 ENOG4105D7V transposase FOA56_10560 ENOG4105Y3U Transglycosylase-associated protein FOA56_10570 ENOG4106G4W FOA56_10575 ENOG410620I Diguanylate cyclase FOA56_10580 ENOG4105UCG Domain of unknown function (DUF333) FOA56_10585 ENOG4105K78 MarR family Transcriptional regulator FOA56_10590 ENOG4105DJ2 Major Facilitator Superfamily FOA56_10595 ENOG4105R1U AraC Family Transcriptional Regulator FOA56_10610 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FOA56_10615 ENOG4108KHP Diguanylate cyclase FOA56_10620 ENOG4106KTS Inner membrane protein yeaI FOA56_10630 ENOG4105CYN Serine protein kinase FOA56_10635 ENOG4105GNX MltA-interacting MipA family protein FOA56_10640 ENOG4105CV8 reductase FOA56_10645 ENOG4105DSB aldose 1-epimerase FOA56_10650 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOA56_10660 ENOG4105VUT cytoplasmic protein FOA56_10665 ENOG4108RWI nicotinamidase FOA56_10670 ENOG4105HDK L-asparaginase FOA56_10675 ENOG4105D07 Signal peptide peptidase, SppA FOA56_10680 ENOG41069NU Nitroreductase FOA56_10690 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOA56_10700 ENOG4105D82 Glutamate dehydrogenase FOA56_10705 ENOG4105MTM Protein of unknown function (DUF1496) FOA56_10710 ENOG4105M6F mutator MutT protein FOA56_10715 ENOG4108T9J Cdp-alcohol phosphatidyltransferase FOA56_10720 ENOG4107RM6 sulfurtransferase FOA56_10725 ENOG4108VGW abc transporter atp-binding protein FOA56_10730 ENOG4105CXZ ABC transporter, permease FOA56_10735 ENOG4105VNH ABC transporter solute-binding protein FOA56_10740 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FOA56_10745 ENOG4108N5C SNARE associated Golgi protein-related protein FOA56_10750 ENOG4108KCW iron-sulfur cluster binding FOA56_10755 ENOG4108RSN SNARE associated Golgi FOA56_10760 ENOG4105CGK Exodeoxyribonuclease III FOA56_10785 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) FOA56_10790 ENOG4108SPG Periplasmic Protein FOA56_10800 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FOA56_10810 ENOG4105KKI DNA-binding transcriptional activator OsmE FOA56_10815 ENOG4105VZJ PTS System FOA56_10820 ENOG4105CK1 PTS System FOA56_10825 ENOG4105VCP PTS System FOA56_10830 ENOG4105EZV Transcriptional regulator FOA56_10835 ENOG4105F8D glycoside hydrolase family 4 FOA56_10845 ENOG4105CH6 catalase FOA56_10860 ENOG4108ETY sodium dicarboxylate symporter FOA56_10865 ENOG4107K5X Membrane-bound metal-dependent hydrolase FOA56_10870 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FOA56_10875 ENOG4107PN8 YfeABCD locus regulator FOA56_10880 ENOG4105FGM Fructosamine kinase FOA56_10885 ENOG4105P10 Uncharacterized protein ydiZ FOA56_10890 ENOG4105DE4 1-phosphofructokinase FOA56_10895 ENOG4108NE3 Salt-induced outer membrane protein FOA56_10920 ENOG41082NX 50s ribosomal protein l35 FOA56_10925 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FOA56_10955 ENOG4108V06 Glutathione peroxidase FOA56_10965 ENOG4108QBX (LipO)protein FOA56_10970 ENOG4108TC0 Diguanylate phosphodiesterase FOA56_10980 ENOG4106EDX Hemin uptake protein FOA56_10985 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FOA56_10995 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOA56_11000 ENOG4105CEY Amp-dependent synthetase and ligase FOA56_11005 ENOG41090P5 ferredoxin-like protein FOA56_11010 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FOA56_11015 ENOG4105C10 Electron transfer flavoprotein FOA56_11020 ENOG4105CV7 Electron transfer flavoprotein FOA56_11025 ENOG4105W4W Transcriptional regulator FOA56_11035 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FOA56_11050 ENOG4105EMV Major Facilitator FOA56_11055 ENOG4105EMV Major Facilitator FOA56_11060 ENOG4105SUA Ydil protein FOA56_11070 ENOG4105IPI Membrane FOA56_11075 ENOG4105CQB FAD linked oxidase domain protein FOA56_11080 ENOG4105KA0 thioesterase Superfamily protein FOA56_11085 ENOG410671Z uncharacterized protein ydiH FOA56_11090 ENOG4108Z4V iron-sulfur cluster assembly FOA56_11095 ENOG4105DIW FeS assembly protein SUFB FOA56_11100 ENOG4105C3K feS assembly ATPase SufC FOA56_11105 ENOG4105JRK feS assembly protein SufD FOA56_11120 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOA56_11125 ENOG4105KMX major outer membrane lipoprotein FOA56_11130 ENOG4105CA9 Pyruvate kinase FOA56_11135 ENOG4105RFR Protein of unknown function (DUF2767) FOA56_11140 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein FOA56_11145 ENOG4105WE2 aldehyde ferredoxin oxidoreductase FOA56_11150 ENOG4105JVW FOA56_11155 ENOG4108393 oxidoreductase Fe-S subunit FOA56_11160 ENOG4108NWD Cytochrome FOA56_11165 ENOG4108Y7C Conserved Protein FOA56_11170 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain FOA56_11175 ENOG4105N0V mono-oxygenase ydhR FOA56_11200 ENOG4108R6K riboflavin synthase, subunit alpha FOA56_11205 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FOA56_11210 ENOG4105CZQ inner membrane transport protein YdhC FOA56_11215 ENOG4105F52 Transcriptional regulator FOA56_11230 ENOG4105F27 Major Facilitator FOA56_11235 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOA56_11240 ENOG4105K4H Nlp p60 protein FOA56_11245 ENOG4105M2J Glutaredoxin FOA56_11250 ENOG4107QRT dEAD DEAH box helicase FOA56_11260 ENOG4108UYE Lactoylglutathione lyase FOA56_11265 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOA56_11270 ENOG4108WUH Transcriptional regulator, TetR family FOA56_11275 ENOG4105XZD Fe-S protein FOA56_11280 ENOG4107RGM aldo keto reductase FOA56_11285 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOA56_11290 ENOG4105DSW Fusaric acid resistance protein FOA56_11295 ENOG4105Y49 secretion protein, HlyD family FOA56_11310 ENOG4108XTF Outer Membrane Lipoprotein FOA56_11320 ENOG410642K Lysozyme inhibitor FOA56_11335 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FOA56_11340 ENOG4108K3A Glutathione S-transferase FOA56_11345 ENOG4105DUX Transporter FOA56_11350 ENOG4105CSM endonuclease III FOA56_11360 ENOG4108UQQ Electron transport complex FOA56_11385 ENOG4105M9B inner membrane protein ydgK FOA56_11390 ENOG4105QZ5 OriC-binding nucleoid-associated protein FOA56_11395 ENOG4106C6R beta-lactam resistance protein FOA56_11400 ENOG4105D9R oxidoreductase FOA56_11410 ENOG4105C87 Aminotransferase class I and II FOA56_11415 ENOG4105CI1 PTS System FOA56_11420 ENOG4107P2S Transcriptional regulator FOA56_11425 ENOG4107ZQV short-chain dehydrogenase reductase FOA56_11430 ENOG4105XEA Tetr family transcriptional regulator FOA56_11435 ENOG4105CNT hydrolase family 2 FOA56_11440 ENOG4105CT4 transporter FOA56_11445 ENOG4108QNI outer membrane porin protein FOA56_11450 ENOG4106J39 exported protein FOA56_11455 ENOG4105EIP mannose-6-phosphate isomerase FOA56_11460 ENOG4107GFK fumarate FOA56_11465 ENOG4105C9Q fumarate hydratase class II FOA56_11475 ENOG4105JJR Histidine kinase FOA56_11480 ENOG4107EXC regulatoR FOA56_11485 ENOG4105RA2 Membrane FOA56_11495 ENOG4105D5Q Arginine ornithine antiporter FOA56_11500 ENOG4105C5D exported protein FOA56_11505 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FOA56_11510 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FOA56_11515 ENOG4105DSF transport protein FOA56_11535 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FOA56_11550 ENOG4105D94 Major Facilitator Superfamily FOA56_11555 ENOG4106NZI LysR family Transcriptional regulator FOA56_11560 ENOG4105DAG ROK family FOA56_11565 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FOA56_11575 ENOG4108NEM leader-binding protein dmsD FOA56_11580 ENOG4107KGK dmso reductase anchor subunit FOA56_11585 ENOG4105QAX Iron-sulfur FOA56_11590 ENOG4105C3J Cysteine desulfurase FOA56_11595 ENOG4107QY8 reductase FOA56_11600 ENOG4105KBG Protein of unknown function (DUF1161) FOA56_11610 ENOG4108MK9 spermidine N(1)-acetyltransferase FOA56_11625 ENOG4105CXK mandelate racemase muconate lactonizing FOA56_11630 ENOG4105CPQ Dehydrogenase FOA56_11640 ENOG4107R08 Integrase FOA56_11655 ENOG4106G8A Qin prophage FOA56_11675 ENOG410649Z repressor FOA56_11680 ENOG4105W7J DNA binding FOA56_11690 ENOG4105YQ0 FOA56_11695 ENOG4105JBR DNA replication protein FOA56_11720 ENOG4105WI6 cell killing protein encoded within cryptic prophage FOA56_11730 ENOG4108MXB Protein of unknown function (DUF968) FOA56_11735 ENOG4105KSK (crossover) junction endodeoxyribonuclease FOA56_11740 ENOG4105HRS Antitermination protein FOA56_11785 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_11800 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FOA56_11805 ENOG4106050 phage regulatory protein, rha family FOA56_11840 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOA56_11915 ENOG4108X9F tail fiber protein FOA56_11960 ENOG4105DEI Mannitol dehydrogenase FOA56_11965 ENOG41061EV selenium-binding protein YdfZ FOA56_11970 ENOG4107XBN GntR Family Transcriptional Regulator FOA56_11975 ENOG4105EMU Dehydrogenase FOA56_11980 ENOG4105DGW oligopeptidase A FOA56_11985 ENOG4108WTK competence damage-inducible protein FOA56_11990 ENOG4108YDI single-species biofilm formation on inanimate substrate FOA56_11995 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FOA56_12005 ENOG4105E5W Transporter FOA56_12010 ENOG4108594 Permease of the drug metabolite transporter FOA56_12015 ENOG4105FDP GntR family transcriptional regulator FOA56_12025 ENOG4105CK1 PTS System FOA56_12030 ENOG4105VCP PTS System FOA56_12040 ENOG4105CS2 ec 3.2.1.21 FOA56_12045 ENOG4106DNR multiple antibiotic resistance protein FOA56_12050 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FOA56_12055 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FOA56_12080 ENOG4105EGI Transcriptional regulator FOA56_12085 ENOG4105C26 Dehydrogenase FOA56_12090 ENOG4105CSV Glutaminase FOA56_12095 ENOG4105M0C cytoplasmic protein FOA56_12100 ENOG4105BZU Histidine kinase FOA56_12110 ENOG4105FFC UPF0187 protein FOA56_12120 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FOA56_12130 ENOG4105D4B ABC, transporter FOA56_12135 ENOG4105F5R ABC transporter FOA56_12145 ENOG4105C2J ABC transporter FOA56_12165 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein FOA56_12170 ENOG4105CAF HipA N-terminal domain protein FOA56_12180 ENOG4108RQP Major type 1 subunit fimbrin FOA56_12190 ENOG4105CW0 outer membrane usher protein FOA56_12195 ENOG4108WDE Fimbrial protein FOA56_12200 ENOG4106318 fimbrial-like protein YdeR FOA56_12205 ENOG4106PIH fimbrial-like protein ydeQ FOA56_12210 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FOA56_12225 ENOG4105ENH Sulfatase FOA56_12230 ENOG4105C4X radical SAM domain protein FOA56_12240 ENOG4105CQ0 ABC transporter FOA56_12245 ENOG4105PE1 Receptor FOA56_12250 ENOG4107RAN Peptidase, M16 FOA56_12255 ENOG4105CVK Glutamate decarboxylase FOA56_12260 ENOG4105E5D amino acid FOA56_12265 ENOG4105F32 YngK protein FOA56_12275 ENOG4105BZU Histidine kinase FOA56_12280 ENOG4108UQS dipeptidase FOA56_12285 ENOG4105DEF Extracellular solute-binding protein, family 5 FOA56_12290 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOA56_12295 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOA56_12300 ENOG4105C3U ABC transporter FOA56_12305 ENOG4107H6U ABC transporter FOA56_12310 ENOG4108Z9K Osmotically inducible protein FOA56_12315 ENOG4105TPS biofilm-dependent modulation protein FOA56_12320 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein FOA56_12330 ENOG4105DQ4 alcohol dehydrogenase FOA56_12335 ENOG41084S7 Plasmid maintenance system antidote protein FOA56_12340 ENOG4108MG3 formate dehydrogenase FOA56_12345 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FOA56_12355 ENOG4105RPH Inner membrane protein YddG FOA56_12365 ENOG4108UI3 Leucine Rich repeat FOA56_12375 ENOG4107QND Nitrite extrusion protein FOA56_12380 ENOG4105CRU nitrate reductase, alpha subunit FOA56_12385 ENOG4108IUE nitrate reductase beta subunit FOA56_12390 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FOA56_12395 ENOG4105D0D Nitrate reductase 2, gamma subunit FOA56_12400 ENOG4105JAB phenazine biosynthesis protein, phzf family FOA56_12405 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOA56_12410 ENOG4108MEJ flavin reductase domain protein FOA56_12430 ENOG4105CNA YD repeat protein FOA56_12465 ENOG4105CS6 Rhs element vgr protein FOA56_12475 ENOG4108N27 Glutathione S-transferase FOA56_12480 ENOG4105C85 amino acid FOA56_12485 ENOG4108NS2 receptor FOA56_12490 ENOG4105CHB tonB-dependent Receptor FOA56_12495 ENOG4108WYP Transcriptional regulator FOA56_12500 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FOA56_12505 ENOG4108Z7F N-acetyltransferase FOA56_12510 ENOG4108T9Y Inner membrane protein ydcZ FOA56_12515 ENOG4105R71 cytoplasmic protein FOA56_12520 ENOG410654E Membrane FOA56_12540 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component FOA56_12545 ENOG4105D81 ABC transporter, permease FOA56_12550 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOA56_12555 ENOG4107TYH extracellular solute-binding protein family 1 FOA56_12560 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOA56_12565 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FOA56_12575 ENOG4105RR0 Protein of unknown function (DUF2554) FOA56_12580 ENOG4105CFP Peptidase U32 FOA56_12585 ENOG4108JCI Transcriptional regulator FOA56_12590 ENOG4105DKK Benzoate FOA56_12595 ENOG4105D7V transposase FOA56_12605 ENOG4108KKZ (LipO)protein FOA56_12610 ENOG41088CC tellurite resistance protein tehB FOA56_12615 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FOA56_12620 ENOG4107WE3 acetyltransferase YdcK FOA56_12625 ENOG4108Z9I -acetyltransferase FOA56_12630 ENOG4105Z2P Protein of unknown function (DUF465) FOA56_12640 ENOG4105E32 cytoplasmic protein FOA56_12645 ENOG4105DDW LysR family Transcriptional regulator FOA56_12650 ENOG4105C8Q Methyl-accepting chemotaxis FOA56_12655 ENOG4107NK6 Hok/gef family FOA56_12660 ENOG4105UPP uncharacterized protein ydcA FOA56_12665 ENOG4105CPW cytochrome b561 FOA56_12670 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOA56_12675 ENOG4105C26 Dehydrogenase FOA56_12680 ENOG4107DB1 DUF218 domain FOA56_12685 ENOG4105CQ7 ATP-dependent helicase FOA56_12695 ENOG41077RS Phosphatase FOA56_12700 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOA56_12705 ENOG4108HPI phosphatidate Cytidylyltransferase FOA56_12710 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FOA56_12720 ENOG4107S5I aldo keto reductase FOA56_12725 ENOG4108Z0R Transferase FOA56_12730 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FOA56_12735 ENOG4105DZS Phenylacetate-CoA ligase FOA56_12740 ENOG4105CHU acetyl-coa acetyltransferase FOA56_12745 ENOG4108ZJI phenylacetic acid degradation protein FOA56_12750 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOA56_12755 ENOG4108UKI Enoyl-CoA hydratase FOA56_12760 ENOG4105E39 Enoyl-CoA hydratase FOA56_12765 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FOA56_12770 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FOA56_12775 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FOA56_12780 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FOA56_12785 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FOA56_12790 ENOG4105DXM phenylacetic acid degradation protein FOA56_12795 ENOG4105F11 amine oxidase FOA56_12800 ENOG4105C26 Dehydrogenase FOA56_12805 ENOG4108WFR AraC Family Transcriptional Regulator FOA56_12810 ENOG4105WXT Conserved Protein FOA56_12815 ENOG410689M (LipO)protein FOA56_12820 ENOG4107H52 Dicarboxylate transport FOA56_12825 ENOG4105C5I Dehydrogenase FOA56_12830 ENOG41090X5 Heat shock protein hslJ FOA56_12840 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FOA56_12845 ENOG4105FCK Membrane FOA56_12850 ENOG4108RW8 Universal stress protein F FOA56_12860 ENOG4105C1J atp-dependent rna helicase FOA56_12870 ENOG4105BZU Histidine kinase FOA56_12875 ENOG4108DG9 Smr protein MutS2 FOA56_12880 ENOG4106KR7 LysR family Transcriptional regulator FOA56_12885 ENOG4105CH2 amidohydrolase FOA56_12890 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B FOA56_12895 ENOG4105CFC Transporter FOA56_12900 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOA56_12905 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FOA56_12910 ENOG4105Q9Y Universal stress protein FOA56_12915 ENOG4105S5I Membrane FOA56_12920 ENOG4105D64 Mechanosensitive ion channel FOA56_12925 ENOG4107QSI ABC, transporter FOA56_12930 ENOG4105EQ2 LysR family Transcriptional regulator FOA56_12935 ENOG4105ENX hydrolase FOA56_12940 ENOG4105ENX hydrolase FOA56_12950 ENOG4105KXI murein peptide amidase A FOA56_12955 ENOG4107S8C mandelate racemase muconate lactonizing FOA56_12960 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOA56_12965 ENOG4108JU8 Transcriptional regulator FOA56_12975 ENOG4105CM6 amino acid regulated cytosolic protein FOA56_12980 ENOG4105FKQ transcriptional regulator FOA56_12985 ENOG4107EFV Outer membrane protein G FOA56_12990 ENOG4108IJ9 (ABC) transporter FOA56_12995 ENOG4107URF beta-phospho-glucomutase FOA56_13000 ENOG4105C71 hydrolase family 65, central catalytic FOA56_13005 ENOG4105CK5 oxidoreductase FOA56_13010 ENOG4107TYA transient receptor potential locus FOA56_13015 ENOG4107RRD Dehydrogenase FOA56_13020 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FOA56_13025 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FOA56_13030 ENOG4105WEM extracellular solute-binding protein FOA56_13035 ENOG4107QW3 Sucrose phosphorylase FOA56_13040 ENOG4105K8Z Phage shock protein FOA56_13045 ENOG4105NNG Peripheral inner membrane phage-shock protein FOA56_13050 ENOG4105FM1 phage shock protein C FOA56_13055 ENOG4105YYT phage shock protein B FOA56_13060 ENOG41087YS Phage shock protein A FOA56_13065 ENOG4105E51 psp operon transcriptional activator FOA56_13070 ENOG4108JPW Aminotransferase FOA56_13075 ENOG4105CJP fad dependent oxidoreductase FOA56_13080 ENOG4105C26 Dehydrogenase FOA56_13085 ENOG4107VRI Transcriptional regulator FOA56_13090 ENOG4108Z86 Glutamine amidotransferase FOA56_13095 ENOG4105CFQ glutamine synthetase FOA56_13105 ENOG4105CUB amino acid FOA56_13110 ENOG4105N0E Protein of unknown function (DUF2543) FOA56_13115 ENOG4108HIY periplasmic FOA56_13120 ENOG4108I5W peptide transport system, permease protein FOA56_13125 ENOG4108EU3 peptide transport system, permease FOA56_13130 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FOA56_13135 ENOG4108JQ2 peptide transport system atp-binding protein FOA56_13140 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FOA56_13145 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FOA56_13150 ENOG4105Q4T oxidoreductase FOA56_13165 ENOG4105BZU Histidine kinase FOA56_13175 ENOG4105N2W Transcriptional regulator FOA56_13180 ENOG41061RM osmotically inducible lipoprotein FOA56_13185 ENOG4108ZJT translation initiation factor, Sui1 FOA56_13195 ENOG4105CFV Tetratricopeptide repeat protein FOA56_13200 ENOG4105Q4A inner membrane protein yciS FOA56_13205 ENOG4105EYK Phosphatidylglycerophosphatase B FOA56_13215 ENOG4107QM5 aconitate hydratase FOA56_13235 ENOG4107R11 Transcriptional regulator FOA56_13240 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOA56_13245 ENOG4105RKX Protein of unknown function (DUF2498) FOA56_13250 ENOG4105ERU peptidase FOA56_13255 ENOG4105UBK short-chain dehydrogenase reductase FOA56_13260 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FOA56_13265 ENOG4105FE9 pseudouridine synthase FOA56_13270 ENOG4107RTD sua5 ycio yrdc ywlc family protein FOA56_13275 ENOG4105DB7 PHP domain protein FOA56_13285 ENOG4105CRQ synthase (Component I) FOA56_13290 ENOG4108EFP Anthranilate synthase component II FOA56_13295 ENOG4105DK0 Indole-3-glycerol phosphate synthase FOA56_13315 ENOG4108Z9Z response to DNA damage stimulus FOA56_13320 ENOG4108N8X transition metal ion binding FOA56_13325 ENOG4105EIF outer membrane protein W FOA56_13345 ENOG4105NAU thioesterase Superfamily protein FOA56_13350 ENOG410822N TonB family FOA56_13355 ENOG4105K9H YciI-like protein FOA56_13360 ENOG4107SVH Potassium channel protein FOA56_13380 ENOG4108JQ7 (ABC) transporter FOA56_13385 ENOG4105C3U ABC transporter FOA56_13390 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOA56_13400 ENOG4108J59 Extracellular solute-binding protein, family 5 FOA56_13405 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FOA56_13410 ENOG4108EKI Dehydrogenase FOA56_13420 ENOG4107104 thymidine kinase FOA56_13425 ENOG4108SAU DNA-binding protein H-ns FOA56_13430 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOA56_13435 ENOG4105I93 response regulator FOA56_13440 ENOG4105D78 K07001 NTE family protein FOA56_13450 ENOG4105CIY formyltetrahydrofolate deformylase FOA56_13475 ENOG41076YT nitrate reductase, gamma subunit FOA56_13480 ENOG4105R3A Nitrate reductase FOA56_13485 ENOG4108IUE nitrate reductase beta subunit FOA56_13490 ENOG4105CRU nitrate reductase, alpha subunit FOA56_13495 ENOG4105DQQ Major facilitator superfamily MFS_1 FOA56_13500 ENOG4105BZU Histidine kinase FOA56_13505 ENOG4105WH1 Two component transcriptional regulator luxr family FOA56_13510 ENOG4105ID0 Putative invasin FOA56_13515 ENOG41090EX DsrE family FOA56_13520 ENOG4108NH8 Cation transport protein FOA56_13525 ENOG4105WS7 Cation transport regulator FOA56_13530 ENOG4105EWV Sodium calcium exchanger membrane region FOA56_13570 ENOG41063JG Transcriptional regulator FOA56_13575 ENOG4108YY7 Invasion gene expression up-regulator SirB FOA56_13580 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOA56_13605 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FOA56_13610 ENOG4105CHH sulfate transporter FOA56_13615 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FOA56_13625 ENOG4105C3G gtp-binding protein FOA56_13630 ENOG4105I1J Autotransporter FOA56_13635 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOA56_13640 ENOG4105CMT Dihydroxyacetone kinase FOA56_13645 ENOG4108UTZ Dihydroxyacetone kinase FOA56_13650 ENOG4105VDH Dihydroxyacetone kinase FOA56_13670 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FOA56_13680 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOA56_13695 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOA56_13705 ENOG4105ED1 spovr family FOA56_13720 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FOA56_13725 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOA56_13730 ENOG4105KT5 UmuD protein FOA56_13745 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FOA56_13755 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FOA56_13760 ENOG4105S66 prophage protein FOA56_13770 ENOG4107QMS site-determining protein FOA56_13805 ENOG410658X FOA56_13825 ENOG4105BZU Histidine kinase FOA56_13830 ENOG410738I uncharacterized protein ymgC FOA56_13840 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB FOA56_13845 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component FOA56_13850 ENOG4105BZU Histidine kinase FOA56_13855 ENOG4108XDN Transcriptional regulator FOA56_13860 ENOG41064WM Uncharacterized protein YcgX FOA56_13875 ENOG4108HMX isocitrate dehydrogenase (NADP) FOA56_13890 ENOG4108C33 Resolvase FOA56_13900 ENOG4105PTU response to oxidative stress FOA56_13910 ENOG4105Y9F tail fiber protein FOA56_13915 ENOG4105Y0G tail protein FOA56_13920 ENOG4108T86 baseplate J family protein FOA56_13940 ENOG4108NKR DNA circulation protein FOA56_13970 ENOG4105TKZ Tail Sheath FOA56_14015 ENOG4105EFC phage portal protein HK97 family FOA56_14025 ENOG4105CAR Terminase, large subunit FOA56_14055 ENOG4105NVB glycoside hydrolase, family 19 FOA56_14080 ENOG4105HGD Antitermination protein FOA56_14085 ENOG4108MXB Protein of unknown function (DUF968) FOA56_14095 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FOA56_14100 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FOA56_14110 ENOG4105YQ0 FOA56_14125 ENOG4108S1U FOA56_14155 ENOG4108R7K Metal Dependent Phosphohydrolase FOA56_14160 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 FOA56_14165 ENOG4108I1J Integrase FOA56_14180 ENOG4108HMX isocitrate dehydrogenase (NADP) FOA56_14185 ENOG4108R99 pseudouridine synthase FOA56_14205 ENOG4107QTF adenylosuccinate lyase FOA56_14210 ENOG4105XJC Two component transcriptional regulator (Winged helix family FOA56_14215 ENOG4105IFJ Histidine kinase FOA56_14220 ENOG4105EZE Cupin 4 family protein FOA56_14235 ENOG4105F38 ABC transporter, permease FOA56_14240 ENOG4105D38 putrescine abc transporter FOA56_14245 ENOG4107RUE extracellular solute-binding protein family 1 FOA56_14260 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOA56_14270 ENOG4105D60 lipoprotein releasing system transmembrane protein FOA56_14275 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOA56_14280 ENOG4105D60 lipoprotein releasing system transmembrane protein FOA56_14285 ENOG4105IQC Inner membrane protein YcfT FOA56_14290 ENOG4108JA2 transcriptioN-repair coupling factor FOA56_14295 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOA56_14300 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FOA56_14305 ENOG4108IND Tetr family transcriptional regulator FOA56_14310 ENOG4107MBR 17 kDa surface antigen FOA56_14315 ENOG4105CEP NADH dehydrogenase FOA56_14335 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FOA56_14340 ENOG41090DQ Lipoprotein FOA56_14345 ENOG4105K59 histidine triad (HIT) protein FOA56_14350 ENOG4105CNM Receptor FOA56_14355 ENOG4105CI1 PTS System FOA56_14360 ENOG4105F8V Hydrolase, tatD family FOA56_14365 ENOG4107QRG dna polymerase iii FOA56_14375 ENOG4105HHA aminodeoxychorismate lyase FOA56_14380 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FOA56_14385 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOA56_14390 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FOA56_14395 ENOG4105CHR reductase FOA56_14400 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOA56_14420 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FOA56_14425 ENOG4108UHJ MAF-like protein FOA56_14430 ENOG4105EI2 Pseudouridine synthase FOA56_14435 ENOG4107QQB Ribonuclease E FOA56_14440 ENOG4105DTJ flagellar hook-associated protein FOA56_14445 ENOG4105E1Q flagellar hook-associated protein FOA56_14450 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FOA56_14465 ENOG4105CGA flagellar basal-body rod protein FlgG FOA56_14470 ENOG4108KPB Flagellar basal-body rod protein FlgF FOA56_14475 ENOG4105BZE flagellar hook protein, FlgE FOA56_14480 ENOG4105W00 Flagellar hook capping protein FOA56_14485 ENOG4108ZC9 flagellar basal-body rod protein flgc FOA56_14490 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOA56_14495 ENOG4105CKS Flagella basal body P-ring formation protein flgA FOA56_14500 ENOG4105M9M anti-sigma28 factor FlgM FOA56_14505 ENOG4105QVD Flagella synthesis protein FlgN FOA56_14510 ENOG4105CJR Integral membrane protein (MviN FOA56_14515 ENOG4105EP9 oxidoreductase FOA56_14525 ENOG4105D9U N-acetyltransferase FOA56_14535 ENOG4105E9S glutaredoxin 2 FOA56_14540 ENOG4105F3T (LipO)protein FOA56_14550 ENOG4105MEA DNA damage-inducible protein i FOA56_14555 ENOG4105PVA Biofilm formation regulatory protein BssS FOA56_14565 ENOG4106974 biofilm formation FOA56_14570 ENOG4105DS1 cytochrome b561 FOA56_14575 ENOG4108YYC ycei family FOA56_14585 ENOG4105D1S lipid A biosynthesis FOA56_14595 ENOG4108W47 Acidic protein msyB FOA56_14600 ENOG4105NAC (LipO)protein FOA56_14605 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FOA56_14620 ENOG4107RZC phospholipase d FOA56_14625 ENOG4108UVJ appr-1-p processing domain protein FOA56_14640 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin FOA56_14645 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FOA56_14650 ENOG41086KC Transcriptional regulator FOA56_14655 ENOG4108XDW curli assembly protein CsgE FOA56_14660 ENOG4108WYR Curli production assembly transport component, CsgF FOA56_14665 ENOG4105P8Q Curli production assembly transport component CsgG FOA56_14670 ENOG4108UQ5 membrane protein YcdZ FOA56_14675 ENOG4107XHZ cytoplasmic chaperone TorD family protein FOA56_14700 ENOG4108T85 Membrane FOA56_14720 ENOG4108TUY outer membrane protein PgaA FOA56_14725 ENOG4107BJW polysaccharide deacetylase FOA56_14730 ENOG4105CND Glycosyl transferase, family 2 FOA56_14735 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FOA56_14740 ENOG4105D5M phosphate starvation-inducible protein FOA56_14745 ENOG4105DBE peroxidase FOA56_14750 ENOG410650H (LipO)protein FOA56_14755 ENOG4105EKT )-iron permease FOA56_14760 ENOG4105CK7 Sodium proline symporter FOA56_14770 ENOG4105C26 Dehydrogenase FOA56_14775 ENOG4108R86 Transcriptional regulator FOA56_14815 ENOG4105C2W permease FOA56_14820 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FOA56_14830 ENOG4105XH3 FOA56_14835 ENOG4105D6F Phosphatase FOA56_14860 ENOG4108J2R molybdopterin oxidoreductase FOA56_14865 ENOG4105CUW cytochrome C-TYPE protein FOA56_14870 ENOG4106WF9 DNA-binding transcriptional regulator TorR FOA56_14875 ENOG4108SV3 Tmao reductase system periplasmic protein tort FOA56_14880 ENOG4105BZU Histidine kinase FOA56_14885 ENOG4105HEE Binding Domain protein FOA56_14890 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FOA56_14905 ENOG4105VEQ Cold shock protein FOA56_14910 ENOG41060EU Cold shock-like protein FOA56_14920 ENOG4108Y9B (LipO)protein FOA56_14925 ENOG4108W78 Pfam:DUF1017 FOA56_14930 ENOG4105E3R (LipO)protein FOA56_14935 ENOG4105DAY polysaccharide export protein FOA56_14940 ENOG4107ZF2 Phosphatase FOA56_14945 ENOG4105D75 Capsular exopolysaccharide family FOA56_14950 ENOG4105D6F Phosphatase FOA56_14960 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOA56_14965 ENOG4105C4M (Ubiquinol oxidase) subunit I FOA56_14970 ENOG4105MVP hydrogenase-1 operon protein HyaF FOA56_14975 ENOG4108VXY Hydrogenase-1 operon protein HyaE FOA56_14980 ENOG4108USZ hydrogenase FOA56_14985 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FOA56_14990 ENOG4105DPX Hydrogenase, large subunit FOA56_14995 ENOG4105E3S small subunit FOA56_15005 ENOG4108MN8 Membrane FOA56_15010 ENOG4108Z0T Part of a sulfur-relay system (By similarity) FOA56_15015 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FOA56_15030 ENOG4105K4P CoA-binding domain protein FOA56_15045 ENOG41088T4 Helicase IV FOA56_15050 ENOG410901E Membrane FOA56_15055 ENOG4105EM2 membrane FOA56_15060 ENOG4108RZ1 DNA transformation protein FOA56_15070 ENOG4105UYK outer membrane protein a FOA56_15080 ENOG4105DAN ATP-dependent protease FOA56_15090 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FOA56_15095 ENOG4108Q2G (LipO)protein FOA56_15100 ENOG4105DY2 Paraquat-inducible protein b FOA56_15105 ENOG4105F1S paraquat-inducible protein a FOA56_15110 ENOG4105C5H ABC transporter FOA56_15120 ENOG4105QVC MOSC domain-containing protein FOA56_15125 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FOA56_15135 ENOG4106PH7 chaperone FOA56_15140 ENOG4105MX3 Fimbrial FOA56_15145 ENOG4105Q7J Fimbrial FOA56_15150 ENOG4108MDY Fimbrial FOA56_15155 ENOG4105CW0 outer membrane usher protein FOA56_15160 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae FOA56_15165 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon FOA56_15170 ENOG4108UZX fmn reductase FOA56_15175 ENOG4105GVF (ABC) transporter FOA56_15185 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOA56_15195 ENOG4105CD8 aminopeptidase N FOA56_15210 ENOG4105FCK Membrane FOA56_15215 ENOG4105CGF Aromatic amino acid aminotransferase FOA56_15220 ENOG4105C5X domain protein FOA56_15225 ENOG4105EAQ (twin-arginine translocation) pathway signal FOA56_15230 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FOA56_15235 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) FOA56_15240 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FOA56_15250 ENOG4106371 Methyltransferase FOA56_15255 ENOG4107S90 membrAne FOA56_15260 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FOA56_15275 ENOG4105T0Z Conserved Protein FOA56_15285 ENOG4105BZ1 (ABC) transporter FOA56_15290 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FOA56_15300 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FOA56_15310 ENOG4108K0D peptidase, M48 FOA56_15325 ENOG4107VMU Membrane FOA56_15330 ENOG4105DDY UPF0142 protein ycaO FOA56_15335 ENOG4105TMB Formate nitrite transporter FOA56_15340 ENOG4105C6N Formate acetyltransferase FOA56_15345 ENOG4105F1A Pyruvate formate-lyase FOA56_15350 ENOG4108X0B nad(p)h dehydrogenase (quinone) FOA56_15355 ENOG410642W LysR family Transcriptional regulator FOA56_15360 ENOG4105E5D amino acid FOA56_15370 ENOG4105CHJ isochorismatase hydrolase FOA56_15375 ENOG4107KGK dmso reductase anchor subunit FOA56_15380 ENOG4105QAX Iron-sulfur FOA56_15385 ENOG4107QY8 reductase FOA56_15395 ENOG4105D1H recombination factor protein RarA FOA56_15405 ENOG4105CNU cell division protein FtsK FOA56_15410 ENOG4105EW9 transcriptional regulator AsnC family FOA56_15415 ENOG4105C3M thioredoxin reductase FOA56_15420 ENOG4108JJ9 ABC, transporter FOA56_15425 ENOG4108JJ8 (ABC) transporter FOA56_15435 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FOA56_15450 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOA56_15460 ENOG4105VEQ Cold shock protein FOA56_15470 ENOG4105DJY efflux transporter, rnd family, mfp subunit FOA56_15475 ENOG4108MJ5 VirK protein FOA56_15480 ENOG4105CPB ATP-dependent endonuclease of the OLD family FOA56_15485 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOA56_15490 ENOG4105DWU Membrane FOA56_15500 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FOA56_15505 ENOG4105C7K acetolactate synthase FOA56_15510 ENOG4105C5W Aldolase FOA56_15515 ENOG4105CGD Nad-dependent epimerase dehydratase FOA56_15520 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOA56_15525 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FOA56_15535 ENOG41064MM (LipO)protein FOA56_15540 ENOG4105E5Z arginine transporter ATP-binding subunit FOA56_15545 ENOG4106PMH Extracellular solute-binding protein family 3 FOA56_15550 ENOG4105GBT ABC transporter FOA56_15555 ENOG4105DMR ABC, transporter FOA56_15560 ENOG4106TNF Periplasmic binding protein FOA56_15570 ENOG4105RBQ inner membrane protein ybjO FOA56_15575 ENOG4105D38 putrescine abc transporter FOA56_15580 ENOG4105F38 ABC transporter, permease FOA56_15585 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOA56_15590 ENOG4107RUE extracellular solute-binding protein family 1 FOA56_15595 ENOG4108RMJ sensory transduction regulator FOA56_15605 ENOG4108DBC nitroreductase FOA56_15610 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FOA56_15615 ENOG41090BQ Glutaredoxin FOA56_15620 ENOG4105GWF inner membrane protein YbjM FOA56_15630 ENOG4105ZTC transcriptional activator, Ogr delta FOA56_15670 ENOG4108C33 Resolvase FOA56_15680 ENOG4108US3 tail fiber assembly FOA56_15685 ENOG4105UZW Tail fiber assembly protein FOA56_15780 ENOG4105ED4 portal protein FOA56_15810 ENOG4105VZ1 Replication Protein FOA56_15815 ENOG4105DFE Dna adenine methylase FOA56_15825 ENOG4105KSC Transcriptional regulator, TraR DksA family FOA56_15850 ENOG4105MEH FOA56_15880 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOA56_15890 ENOG4108RFG Tetr family transcriptional regulator FOA56_15895 ENOG4106UW1 Major Facilitator superfamily FOA56_15900 ENOG4108HCJ Hydrolase FOA56_15910 ENOG4107QF7 multi-drug FOA56_15915 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOA56_15920 ENOG4107FB0 transcriptional regulator DeoR family FOA56_15925 ENOG4105DZ1 carboxypeptidase FOA56_15930 ENOG4108TGY Glutathione S-transferase FOA56_15935 ENOG4105D8V Glucose sorbosone dehydrogenase FOA56_15940 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FOA56_15955 ENOG4105BZU Histidine kinase FOA56_15960 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOA56_15980 ENOG4105D44 asparaginase FOA56_15985 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOA56_15990 ENOG4105D06 uba thif-type nad fad binding protein FOA56_15995 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOA56_16000 ENOG4105F1A Pyruvate formate-lyase FOA56_16005 ENOG4105C6N Formate acetyltransferase FOA56_16010 ENOG4108HCJ Hydrolase FOA56_16015 ENOG41072TH Protein of unknown function (DUF1479) FOA56_16030 ENOG4105C5H ABC transporter FOA56_16035 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOA56_16040 ENOG4105F4P )-transporter FOA56_16045 ENOG4105KST dependent repressor FOA56_16055 ENOG4108I6E Sulfatase FOA56_16060 ENOG4108T1M outer membrane protein x FOA56_16070 ENOG4107AQZ Membrane FOA56_16080 ENOG4107R0W ABC transporter FOA56_16085 ENOG4105E5Q amino acid AbC transporter FOA56_16090 ENOG4105CDA abc transporter atp-binding protein FOA56_16095 ENOG4105D8X mechanosensitive ion channel FOA56_16105 ENOG4105ZY9 UPF0379 protein ybiM FOA56_16110 ENOG4108IU3 tonb-dependent siderophore receptor FOA56_16120 ENOG4105KSC Transcriptional regulator, TraR DksA family FOA56_16125 ENOG4105VR4 UPF0379 protein ybiJ FOA56_16130 ENOG4105DG4 malate L-lactate dehydrogenase FOA56_16135 ENOG4108MTB glycosyl transferase family FOA56_16140 ENOG4105DVT helicase FOA56_16145 ENOG4108UV1 cellular component movement FOA56_16150 ENOG4105C1J atp-dependent rna helicase FOA56_16155 ENOG4107MVR Transcriptional regulator FOA56_16165 ENOG4105CJ1 ABC, transporter FOA56_16170 ENOG4107QWP ABC-2 type transporter FOA56_16175 ENOG4107QWP ABC-2 type transporter FOA56_16180 ENOG4105I9U inner membrane protein ybhQ FOA56_16185 ENOG4105X23 Endonuclease Exonuclease phosphatase FOA56_16190 ENOG4105DZQ phospholipase D Transphosphatidylase FOA56_16195 ENOG4107UXM Membrane FOA56_16200 ENOG410733J conserved inner membrane protein FOA56_16210 ENOG4105HFZ Membrane FOA56_16215 ENOG4108ZAF Molybdopterin FOA56_16220 ENOG4105M00 molybdopterin converting factor, subunit 1 FOA56_16230 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOA56_16240 ENOG4105CHW UPF0052 protein FOA56_16250 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FOA56_16255 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOA56_16270 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOA56_16275 ENOG4108V1U phospholipid-binding protein FOA56_16480 ENOG4105FKG DNA packaging protein FOA56_16490 ENOG4106YSC FOA56_16500 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FOA56_16505 ENOG4105KUS lysozyme FOA56_16510 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_16570 ENOG4105RWQ Protein of unknown function (DUF1364) FOA56_16600 ENOG4105NY2 NinB protein FOA56_16730 ENOG4108I1J Integrase FOA56_16735 ENOG4105NBR Pectinesterase FOA56_16740 ENOG4107QM5 aconitate hydratase FOA56_16745 ENOG4107QPK )-transporter FOA56_16750 ENOG4105C7F AcnD-accessory protein PrpF FOA56_16755 ENOG4105F04 LysR family Transcriptional regulator FOA56_16765 ENOG4108K4B hydrolase FOA56_16770 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FOA56_16775 ENOG4105E0C molybdate abc transporter FOA56_16780 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOA56_16785 ENOG410680R Protein of unknown function (DUF2592) FOA56_16790 ENOG4105F4R Transcriptional regulator mode FOA56_16795 ENOG4105DKW ABC transporter FOA56_16800 ENOG4105CMR udp-glucose 4-epimerase FOA56_16805 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FOA56_16815 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FOA56_16825 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FOA56_16830 ENOG4105JND homeobox protein FOA56_16835 ENOG4105PGM cation diffusion facilitator family transporter FOA56_16840 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FOA56_16890 ENOG4105UFD tol-pal system protein YbgF FOA56_16895 ENOG4105KCK Peptidoglycan-associated lipoprotein FOA56_16905 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FOA56_16910 ENOG4105M8F Biopolymer transport protein exbD tolR FOA56_16915 ENOG4105E02 MotA TolQ exbB proton channel FOA56_16920 ENOG4107YD3 Thioesterase FOA56_16925 ENOG4105KJB cyd operon protein YbgE FOA56_16935 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOA56_16940 ENOG4105C4M (Ubiquinol oxidase) subunit I FOA56_16945 ENOG4105C8I hydrolase, family 38 FOA56_16950 ENOG4105DM4 PTS System FOA56_16955 ENOG4105FDP GntR family transcriptional regulator FOA56_16960 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOA56_16970 ENOG4105C7S Dehydrogenase FOA56_16975 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FOA56_16980 ENOG4105E33 succinate dehydrogenase FOA56_16985 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FOA56_16990 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FOA56_16995 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FOA56_17005 ENOG4105BZN citrate synthase FOA56_17010 ENOG4106UBK fimbrial-like adhesin protein FOA56_17015 ENOG4106PG1 outer membrane usher protein FOA56_17020 ENOG4108TTM chaperone FOA56_17025 ENOG4108MY7 Fimbrial FOA56_17030 ENOG4108KK1 membrane protein AbrB duplication FOA56_17040 ENOG4105E7W lamb ycsf family protein FOA56_17045 ENOG4107R7A Allophanate hydrolase subunit 2 FOA56_17050 ENOG4105P4J Allophanate hydrolase, subunit 1 FOA56_17055 ENOG4107QNR UPF0135 protein FOA56_17060 ENOG4105DUX Transporter FOA56_17065 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOA56_17070 ENOG4107SEY Conserved Protein FOA56_17085 ENOG4106R09 FOA56_17095 ENOG41079JQ Membrane FOA56_17100 ENOG4105CNA YD repeat protein FOA56_17105 ENOG4105XIQ Protein of unknown function (DUF2517) FOA56_17130 ENOG4105C08 Histidine kinase FOA56_17135 ENOG4105EEX Two component transcriptional regulator (Winged helix family FOA56_17150 ENOG4105CXN decarboxylase FOA56_17155 ENOG4105D5Q Arginine ornithine antiporter FOA56_17160 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FOA56_17165 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FOA56_17170 ENOG4105EV9 Alpha Beta Hydrolase FOA56_17175 ENOG4105NNH LexA regulated protein FOA56_17180 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FOA56_17190 ENOG41090R7 Ferric uptake FOA56_17195 ENOG4105GX6 (LipO)protein FOA56_17210 ENOG4105CI1 PTS System FOA56_17220 ENOG4105CE4 GlcNAc 6-P deacetylase FOA56_17225 ENOG4105E2R ROK family FOA56_17230 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOA56_17235 ENOG4105CAQ asparagine synthetase FOA56_17275 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FOA56_17285 ENOG4105C9A Phoh family FOA56_17295 ENOG4108JU5 Magnesium and cobalt efflux protein FOA56_17300 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FOA56_17315 ENOG4107RP9 extracellular solute-binding protein, family 3 FOA56_17320 ENOG4105EAD ABC transporter FOA56_17325 ENOG4105DRP amino acid AbC transporter FOA56_17330 ENOG4105CDA abc transporter atp-binding protein FOA56_17340 ENOG4105F7F Chaperone FOA56_17345 ENOG4105QFC Hsc56 co-chaperone of HscC FOA56_17350 ENOG41069CF Protein of unknown function (DUF1266) FOA56_17355 ENOG4107JFD Sel1 repeat FOA56_17360 ENOG4105QFC Hsc56 co-chaperone of HscC FOA56_17365 ENOG41069CF Protein of unknown function (DUF1266) FOA56_17370 ENOG4105EUU Sel1 domain protein repeat-containing protein FOA56_17375 ENOG4107PAI alpha helical protein FOA56_17390 ENOG4105DJF DNA polymerase III, delta' subunit FOA56_17400 ENOG4108TGR phosphatase FOA56_17405 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FOA56_17415 ENOG4105CJN penicillin-binding protein FOA56_17420 ENOG4105CNI cell division protein FtsW FOA56_17425 ENOG4105K6T rare lipoprotein A FOA56_17430 ENOG4105DZ1 carboxypeptidase FOA56_17455 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) FOA56_17460 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOA56_17470 ENOG4105VEQ Cold shock protein FOA56_17475 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FOA56_17480 ENOG4105CEE C4-dicarboxylate transporter FOA56_17485 ENOG4106YYS transcriptional regulatory protein FOA56_17490 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOA56_17495 ENOG4105DUA (citrate (pro-3S)-lyase ligase FOA56_17505 ENOG4105CI0 Citrate lyase FOA56_17510 ENOG4105CHY citrate lyase, alpha FOA56_17525 ENOG4107QPK )-transporter FOA56_17530 ENOG4105KTS ribonuclease FOA56_17535 ENOG4105NXH GreA GreB family elongation factor FOA56_17540 ENOG4105E2A Dehydrogenase FOA56_17545 ENOG4108U51 Universal stress protein FOA56_17550 ENOG4108JU3 Alkyl hydroperoxide reductase FOA56_17555 ENOG4105D3R alkyl hydroperoxide reductase FOA56_17560 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FOA56_17565 ENOG4105DQS Transcriptional regulator FOA56_17570 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FOA56_17575 ENOG4105GTN ParB Domain Protein Nuclease FOA56_17580 ENOG4105CHM Aminotransferase FOA56_17585 ENOG4107SCQ Iron-containing alcohol dehydrogenase FOA56_17590 ENOG4105VCD cytoplasmic protein FOA56_17595 ENOG4105D22 carbon starvation protein FOA56_17600 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FOA56_17605 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOA56_17610 ENOG4105WQI isochorismatase FOA56_17615 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOA56_17620 ENOG4105E4F Isochorismate synthase FOA56_17625 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FOA56_17635 ENOG4105DQ5 transport system permease protein FOA56_17640 ENOG4105TVJ transport system, permease FOA56_17645 ENOG4105E0A ABC, transporter FOA56_17655 ENOG4105C0W non-ribosomal peptide synthetase FOA56_17660 ENOG41085A6 mbth domain-containing protein FOA56_17665 ENOG4105E93 esterase FOA56_17670 ENOG4107RNH Outer membrane receptor FepA FOA56_17675 ENOG4108TSE Transferase FOA56_17680 ENOG4107635 Hok Gef family protein FOA56_17695 ENOG4105WQ6 Membrane FOA56_17700 ENOG4105MSB protein, conserved in bacteria FOA56_17705 ENOG4108RCM Nitroreductase FOA56_17710 ENOG4105CUY Mechanosensitive ion channel FOA56_17715 ENOG4105C85 amino acid FOA56_17720 ENOG4108IJF Heavy metal efflux pump, CzcA FOA56_17725 ENOG4105EP1 Efflux transporter rnd family, mfp subunit FOA56_17730 ENOG410624V efflux system protein FOA56_17735 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FOA56_17740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOA56_17745 ENOG4105GR3 Histidine kinase FOA56_17750 ENOG4105CS6 Rhs element vgr protein FOA56_17760 ENOG4105CNA YD repeat protein FOA56_17795 ENOG410600T transposase FOA56_17800 ENOG410802X bacteriophage n4 adsorption protein b FOA56_17805 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit FOA56_17810 ENOG4105QUW FOA56_17820 ENOG4108NC2 Outer membrane protease FOA56_17845 ENOG4105W3V DNA-binding, transcriptional regulator FOA56_17850 ENOG4105MN3 Resolvase FOA56_17855 ENOG4105UZW Tail fiber assembly protein FOA56_17860 ENOG4108X9F tail fiber protein FOA56_17935 ENOG4105IM0 capsid protein FOA56_17945 ENOG4105F7J membrane-bound serine protease FOA56_17955 ENOG4107DE1 head-to-tail joining protein FOA56_17960 ENOG4105UZW Tail fiber assembly protein FOA56_17965 ENOG4105FKG DNA packaging protein FOA56_17970 ENOG4106YSC FOA56_17985 ENOG4105QYK bacteriophage lambda Bor protein homolog FOA56_17995 ENOG4105KUS lysozyme FOA56_18000 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_18010 ENOG4105HRS Antitermination protein FOA56_18015 ENOG4108MXB Protein of unknown function (DUF968) FOA56_18025 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FOA56_18030 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FOA56_18040 ENOG4105YQ0 FOA56_18050 ENOG4108S1U FOA56_18075 ENOG4105H40 FOA56_18080 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) FOA56_18085 ENOG4108R7K Metal Dependent Phosphohydrolase FOA56_18090 ENOG41077V0 CPS-53 (KpLE1) prophage FOA56_18105 ENOG4108KU3 Integrase FOA56_18115 ENOG4108Q9V regulatoR FOA56_18120 ENOG4108ZI2 Fimbrial protein FOA56_18125 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FOA56_18130 ENOG4105CW0 outer membrane usher protein FOA56_18135 ENOG4108AF8 Chaperone FOA56_18140 ENOG4108WDE Fimbrial protein FOA56_18150 ENOG4105WQ3 Rna-binding protein FOA56_18155 ENOG4105S2T inner membrane protein YbcI FOA56_18165 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FOA56_18175 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOA56_18180 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOA56_18185 ENOG4105C5B carbamate kinase FOA56_18190 ENOG4105G5A Protein of unknown function (DUF2877) FOA56_18195 ENOG4107REC cytoplasmic protein FOA56_18200 ENOG4107R1Q Membrane protein FdrA FOA56_18205 ENOG4105DG4 malate L-lactate dehydrogenase FOA56_18210 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FOA56_18215 ENOG4105S0E allantoin catabolism protein FOA56_18220 ENOG4105BZW Glycerate kinase FOA56_18225 ENOG4105DTE Xanthine uracil vitamin C permease FOA56_18235 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FOA56_18240 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOA56_18245 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FOA56_18250 ENOG41060W2 glyoxylate carboligase FOA56_18255 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region FOA56_18260 ENOG4108Z2U ureidoglycolate hydrolase FOA56_18265 ENOG4107653 Transcriptional regulator FOA56_18295 ENOG4105CNA YD repeat protein FOA56_18300 ENOG4105CV6 ABC transporter, permease FOA56_18305 ENOG4108I0Y (ABC) transporter FOA56_18310 ENOG4108UJV acyl-CoA thioesterase i FOA56_18315 ENOG4105E1F short-chain dehydrogenase reductase FOA56_18320 ENOG4107QR8 Thioredoxin FOA56_18325 ENOG4105C4B ABC transporter, permease FOA56_18330 ENOG41083J0 (ABC) transporter FOA56_18335 ENOG4107QX8 SPFH domain, Band 7 family protein FOA56_18340 ENOG4105G5H Membrane FOA56_18345 ENOG4108Z6Z Transcriptional regulator FOA56_18350 ENOG4107RY6 amino acid FOA56_18355 ENOG4105CSV Glutaminase FOA56_18360 ENOG4105C59 p-type ATPase FOA56_18365 ENOG41081XE plasmid maintenance system antidote protein, xre family FOA56_18375 ENOG4105MBR gumn family FOA56_18380 ENOG4108Z66 YbaK ebsC protein FOA56_18385 ENOG4105CGH 5'-nucleotidase FOA56_18390 ENOG4105EU0 Major facilitator Superfamily FOA56_18395 ENOG4105CKD glutathione-regulated potassium-efflux system protein FOA56_18400 ENOG4107RE1 Inosine-guanosine kinase FOA56_18440 ENOG4107QMP dna polymerase iii subunits gamma and tau FOA56_18450 ENOG4105WD1 Membrane FOA56_18455 ENOG4108URS primosomal replication protein n'' FOA56_18460 ENOG4106428 Protein of unknown function (DUF2496) FOA56_18465 ENOG4105EGS Mechanosensitive ion channel FOA56_18470 ENOG4108IG5 Transcriptional regulator FOA56_18475 ENOG4105C1P efflux transporter, rnd family, mfp subunit FOA56_18480 ENOG4105BZS acriflavin resistance protein FOA56_18485 ENOG4108UKR Biofilm formation regulator YbaJ FOA56_18490 ENOG4105KF5 hemolysin expression-modulating protein FOA56_18495 ENOG4108UW5 maltose o-acetyltransferase FOA56_18500 ENOG4105GSJ Inner membrane protein ylaC FOA56_18505 ENOG41066DG (EAL) domain protein FOA56_18510 ENOG4105KCV RNA signal recognition particle 4.5S RNA FOA56_18520 ENOG41080UX Methyltransferase FOA56_18525 ENOG4108MNP Glycoprotein polysaccharide metabolism FOA56_18530 ENOG4105C29 acyl-CoA thioesterase FOA56_18535 ENOG4105BZU Histidine kinase FOA56_18540 ENOG4108YZA Nitrogen regulatory protein pii FOA56_18545 ENOG4105BZ1 (ABC) transporter FOA56_18550 ENOG4105BZ1 (ABC) transporter FOA56_18555 ENOG4108XM1 transcriptional regulator AsnC family FOA56_18565 ENOG4108NFA extracellular solute-binding protein FOA56_18575 ENOG4108TGP Thioesterase superfamily protein FOA56_18580 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FOA56_18585 ENOG4105EIN peptidylprolyl cis-trans isomerase FOA56_18590 ENOG4105K70 DNA-binding protein FOA56_18595 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FOA56_18615 ENOG4105M85 Bola protein FOA56_18620 ENOG4105IEY (LipO)protein FOA56_18625 ENOG4105EYM Major Facilitator superfamily FOA56_18630 ENOG4105E2S oxidase) subunit II FOA56_18635 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOA56_18640 ENOG4105CCU oxidase (Subunit III) FOA56_18645 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FOA56_18670 ENOG4107RDB Major Facilitator FOA56_18680 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOA56_18685 ENOG4107S0N DJ-1 family FOA56_18700 ENOG4105CTB Polyprenyl synthetase FOA56_18710 ENOG4105CPC Aldo Keto reductase FOA56_18715 ENOG4108ZAI phosphatidylglycerophosphatase a FOA56_18720 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FOA56_18730 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FOA56_18735 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOA56_18745 ENOG4108KIC (LipO)protein FOA56_18750 ENOG4105DRB nucleoside-specific channel-forming protein FOA56_18755 ENOG4105N1F Hnh endonuclease FOA56_18760 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOA56_18765 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOA56_18770 ENOG4105VIE preprotein translocase, subunit YajC FOA56_18780 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FOA56_18790 ENOG4107R28 alpha amylase, catalytic region FOA56_18795 ENOG4105C85 amino acid FOA56_18800 ENOG4105CWM branched-chain amino acid transport system II carrier protein FOA56_18805 ENOG4105BZU Histidine kinase FOA56_18810 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOA56_18815 ENOG4107RH8 nuclease SbcCD subunit D FOA56_18820 ENOG4105EYH Exonuclease FOA56_18825 ENOG4105F27 Major Facilitator FOA56_18830 ENOG4105DKQ ROK family FOA56_18855 ENOG4105HBA AroM protein FOA56_18860 ENOG4105SS3 FOA56_18875 ENOG4105II7 pyrroline-5-carboxylate reductase FOA56_18880 ENOG4105BZU Histidine kinase FOA56_18885 ENOG4105VIF phosphate starvation-inducible protein FOA56_18890 ENOG4105G6Z alkaline phosphatase FOA56_18900 ENOG4105CPF Cell wall formation (By similarity) FOA56_18905 ENOG4105UNH Membrane FOA56_18910 ENOG4105FR5 inner membrane protein YaiY FOA56_18915 ENOG4107QS8 (LipO)protein FOA56_18920 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FOA56_18925 ENOG4107R6D beta-lactam binding protein AmpH FOA56_18930 ENOG4108PNB DNA-binding transcriptional regulator FOA56_18940 ENOG4105D52 delta-aminolevulinic acid dehydratase FOA56_18945 ENOG4105E2B Taurine dioxygenase FOA56_18950 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOA56_18955 ENOG4108IY8 ABC, transporter FOA56_18960 ENOG4106FTQ Taurine ABC transporter, periplasmic FOA56_18965 ENOG4107W19 lmbE family FOA56_18970 ENOG4108PBI Polysaccharide metabolism FOA56_18980 ENOG4105SRB Uncharacterized protein yaiO FOA56_18995 ENOG4105C4W S-formylglutathione hydrolase FOA56_19000 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FOA56_19005 ENOG4108SC4 )-transporter FOA56_19030 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) FOA56_19040 ENOG4108K2P TRANSCRIPTIONal FOA56_19045 ENOG4105ETE Transcriptional regulator (LacI family FOA56_19055 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FOA56_19060 ENOG4108UW5 maltose o-acetyltransferase FOA56_19075 ENOG4105DJ2 Major Facilitator Superfamily FOA56_19085 ENOG4107B2H carbonic anhydrase FOA56_19090 ENOG4105DND Transcriptional regulator FOA56_19095 ENOG4105DZC cytosine deaminase FOA56_19100 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FOA56_19115 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOA56_19120 ENOG4105DXD 2-methylcitrate dehydratase FOA56_19125 ENOG4105BZN citrate synthase FOA56_19130 ENOG4105CR4 methylisocitrate lyase FOA56_19135 ENOG4108JU7 Transcriptional regulator FOA56_19140 ENOG4105TDT uncharacterized protein yahO FOA56_19145 ENOG4105E82 cytochrome subunit of dehydrogenase FOA56_19160 ENOG4105DQ4 alcohol dehydrogenase FOA56_19165 ENOG4105CNN ABC, transporter FOA56_19170 ENOG4105CNN ABC, transporter FOA56_19175 ENOG4105C2J ABC transporter FOA56_19180 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOA56_19190 ENOG4105DZC cytosine deaminase FOA56_19195 ENOG4105C5B carbamate kinase FOA56_19200 ENOG4107REC cytoplasmic protein FOA56_19205 ENOG4107R1Q Membrane protein FdrA FOA56_19210 ENOG4105N16 Protein of unknown function (DUF2877) FOA56_19215 ENOG4107SNB ankyrin repeat protein YahD FOA56_19220 ENOG4105SZ2 membrAne FOA56_19225 ENOG4108NUU Transcriptional regulator FOA56_19230 ENOG4105BZU Histidine kinase FOA56_19240 ENOG4105C94 Transporter FOA56_19245 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FOA56_19265 ENOG4108W9T type 1 fimbriae regulatory protein FOA56_19270 ENOG4105BZU Histidine kinase FOA56_19295 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FOA56_19300 ENOG4107QR9 Iron-sulfur cluster binding protein FOA56_19305 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOA56_19310 ENOG4108K01 transcriptional regulator FOA56_19315 ENOG4107QN2 dihydrolipoyl dehydrogenase FOA56_19320 ENOG41066GK UPF0379 protein ykgI FOA56_19325 ENOG4108KBJ Inner membrane protein YkgB FOA56_19330 ENOG4105CV8 reductase FOA56_19385 ENOG4108N3D putative enzyme FOA56_19390 ENOG4106PYX Receptor FOA56_19395 ENOG4108UD7 cell wall organization FOA56_19400 ENOG4105PI0 Ferredoxin FOA56_19405 ENOG4105R3P Inner membrane protein yagU FOA56_19410 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FOA56_19415 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FOA56_19420 ENOG4105C7W Xanthine dehydrogenase FOA56_19425 ENOG4107XAN XdhC and CoxI family FOA56_19450 ENOG4105FCK Membrane FOA56_19470 ENOG4105CIN aminoacyl-histidine dipeptidase FOA56_19475 ENOG4108S2Y peptide Chain Release factor FOA56_19485 ENOG4108HYG acetyltransferase FOA56_19490 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOA56_19515 ENOG4108YS0 lipoprotein YafL FOA56_19525 ENOG4105VXN addiction module toxin, RelE StbE family FOA56_19530 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FOA56_19535 ENOG4105E7A Glutamine amidotransferase FOA56_19545 ENOG4107QPN acyl-Coa dehydrogenase FOA56_19550 ENOG4108WN0 inhibitor of vertebrate lysozyme FOA56_19555 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOA56_19560 ENOG410600T transposase FOA56_19565 ENOG410600T transposase FOA56_19575 ENOG4105CNA YD repeat protein FOA56_19580 ENOG4105CS6 Rhs element vgr protein FOA56_19585 ENOG4108WC9 type VI secretion system effector, hcp1 family FOA56_19640 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOA56_19665 ENOG4105GMB type VI secretion system effector, hcp1 family FOA56_19680 ENOG410600K aminopeptidase FOA56_19690 ENOG4107RZZ dna polymerase iii epsilon subunit FOA56_19700 ENOG4105D1A Methyltransferase FOA56_19710 ENOG4105E9H Lytic Murein transglycosylase FOA56_19715 ENOG4105F2W methyltransferase FOA56_19725 ENOG4105HEI LysR family (Transcriptional regulator FOA56_19730 ENOG4105CV8 reductase FOA56_19765 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOA56_19770 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOA56_19775 ENOG4108UMI ABC transporter, permease FOA56_19780 ENOG4105D01 (LipO)protein FOA56_19785 ENOG4108R8X outer membrane lipoprotein FOA56_19790 ENOG4108R96 Methyltransferase, YaeB family FOA56_19815 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FOA56_19820 ENOG4108YZN class I peptide chain release factor FOA56_19825 ENOG4108VWS Yaeq family FOA56_19835 ENOG4105M1T rho-binding antiterminator FOA56_19840 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FOA56_19845 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOA56_19850 ENOG4105CXN decarboxylase FOA56_19860 ENOG4105C0B DNA polymerase III (alpha subunit) FOA56_19885 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FOA56_19890 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FOA56_19900 ENOG4105DZP Membrane-associated zinc metalloprotease FOA56_19905 ENOG4105KNE Phosphatidate cytidylyltransferase FOA56_19910 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FOA56_19915 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FOA56_19940 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOA56_19960 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FOA56_19965 ENOG4105C0H protease FOA56_19980 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FOA56_19985 ENOG4105EN6 Membrane FOA56_20010 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOA56_20015 ENOG4105J76 Periplasmic binding protein FOA56_20020 ENOG4105E0A ABC, transporter FOA56_20025 ENOG4105E0K tonB-dependent siderophore receptor FOA56_20030 ENOG4105BZ4 penicillin-binding protein FOA56_20035 ENOG4105CQ7 ATP-dependent helicase FOA56_20040 ENOG4107XID 2'-5' rna ligase FOA56_20050 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FOA56_20055 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FOA56_20060 ENOG4105DJ0 Poly(A) Polymerase FOA56_20065 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOA56_20075 ENOG4108VEV chaperone FOA56_20085 ENOG4108XEY fimbrial-like adhesin protein FOA56_20090 ENOG4105SYG Fimbrial protein FOA56_20095 ENOG4105SN2 fimbrial-like adhesin protein FOA56_20100 ENOG4105P0Q fimbrial-like protein YadC FOA56_20115 ENOG4108A32 Transposase FOA56_20125 ENOG4107BJW polysaccharide deacetylase FOA56_20130 ENOG4108YTN IIa component FOA56_20135 ENOG4105E3A (ABC) transporter FOA56_20140 ENOG4105DA5 (ABC) transporter FOA56_20145 ENOG41077A9 carbonic anhydrase FOA56_20150 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOA56_20155 ENOG4105DZG Dehydrogenase FOA56_20160 ENOG4105E3B Multicopper oxidase FOA56_20165 ENOG4108ZRK uncharacterized protein yacC FOA56_20185 ENOG4107QIJ Aconitate hydratase 2 FOA56_20190 ENOG4108NST exported protein FOA56_20195 ENOG4107QN2 dihydrolipoyl dehydrogenase FOA56_20200 ENOG4107QSN dihydrolipoamide acetyltransferase FOA56_20205 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FOA56_20210 ENOG41073TP transcriptional regulator FOA56_20215 ENOG4105C85 amino acid FOA56_20220 ENOG4106A72 regulatory protein AmpE FOA56_20225 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FOA56_20230 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOA56_20235 ENOG4108ZUW Major pilin subunit FOA56_20240 ENOG4107QHF type ii secretion system protein e FOA56_20245 ENOG4105D7Q type ii secretion system FOA56_20255 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOA56_20270 ENOG4105M6F mutator MutT protein FOA56_20290 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOA56_20295 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOA56_20300 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FOA56_20305 ENOG4105CPF Cell wall formation (By similarity) FOA56_20320 ENOG4105CNI cell division protein FtsW FOA56_20335 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FOA56_20340 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOA56_20345 ENOG4105CJN penicillin-binding protein FOA56_20350 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FOA56_20365 ENOG4107B7Y DNA-binding transcriptional regulator FruR FOA56_20375 ENOG4108ZP8 Acetolactate synthase small subunit FOA56_20380 ENOG4105C7K acetolactate synthase FOA56_20385 ENOG41064T2 transcriptional regulator, lysR family FOA56_20415 ENOG4105S8Q sugar efflux transporter FOA56_20430 ENOG4105DP9 ABC transporter FOA56_20435 ENOG4106SMU thiamine transporter membrane protein FOA56_20445 ENOG4108KF1 Membrane FOA56_20450 ENOG41063TF transcriptional regulator (AraC FOA56_20455 ENOG4105EF1 ribulokinase FOA56_20465 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FOA56_20470 ENOG4105CQ2 DNA polymerase FOA56_20480 ENOG4105D3G Pseudouridine synthase FOA56_20485 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) FOA56_20490 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FOA56_20495 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FOA56_20515 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOA56_20535 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FOA56_20550 ENOG4105C54 Major Facilitator superfamily FOA56_20555 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein FOA56_20560 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FOA56_20595 ENOG4106YT9 Enoyl-CoA hydratase FOA56_20605 ENOG4108XNW Transcriptional activatory protein CaiF FOA56_20610 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FOA56_20615 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FOA56_20635 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FOA56_20650 ENOG4105DTN riboflavin biosynthesis protein ribF FOA56_20655 ENOG410647N response to DNA damage stimulus FOA56_20680 ENOG41063Z6 transcriptional regulator, lysR family FOA56_20690 ENOG4105WI6 cell killing protein encoded within cryptic prophage FOA56_20710 ENOG4108QUJ UPF0174 protein YaaW FOA56_20715 ENOG4106HK8 GPR1 FUN34 yaaH family protein FOA56_20720 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOA56_20730 ENOG4105BZG amino acid carrier protein FOA56_20735 ENOG4105D1Q UPF0246 protein FOA56_20750 ENOG41062C6 Protein of unknown function (DUF2502) FOA56_20755 ENOG4105D98 threonine synthase FOA56_20765 ENOG4105CFH Aspartokinase FOA56_20775 ENOG4106FVC RNA methyltransferase FOA56_20780 ENOG410759A FOA56_20785 ENOG41065U4 response regulator FOA56_20790 ENOG4105CT7 inner membrane cred family protein FOA56_20795 ENOG4105EB3 Histidine kinase FOA56_20800 ENOG4105E3W Two component transcriptional regulator (Winged helix family FOA56_20805 ENOG4108RH0 Crea protein FOA56_20810 ENOG4105UEI Transcriptional Regulator AraC Family FOA56_20820 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FOA56_20840 ENOG4107SC1 transglycosylase FOA56_20845 ENOG4105C5H ABC transporter FOA56_20850 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FOA56_20855 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOA56_20860 ENOG4105EAC phosphoserine phosphatase FOA56_20865 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) FOA56_20895 ENOG4105G0K glycine radical enzyme YjjI family FOA56_20900 ENOG41076CZ activating enzyme FOA56_20905 ENOG4105EYA deoxyribonuclease FOA56_20910 ENOG4108NRW Phospholipase, patatin family FOA56_20920 ENOG4105K3G Periplasmic Protein FOA56_20930 ENOG4105PAD Hydrolase FOA56_20935 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FOA56_20940 ENOG4108WPU DNA polymerase III subunit psi FOA56_20965 ENOG4105YBH Protein of unknown function (DUF1435) FOA56_20970 ENOG4108819 ferric iron reductase FOA56_20975 ENOG4108T94 DNA-binding transcriptional activator BglJ FOA56_20980 ENOG4108N8T regulatoR FOA56_20985 ENOG4105DWK Membrane FOA56_21000 ENOG4106CVF DNA replication protein FOA56_21005 ENOG4105RI1 glycoprotein receptor FOA56_21015 ENOG4105CPQ Dehydrogenase FOA56_21020 ENOG410617M Transcriptional regulator FOA56_21025 ENOG4108I5G Major Facilitator superfamily FOA56_21030 ENOG4105C8Q Methyl-accepting chemotaxis FOA56_21035 ENOG4108V8F Transcriptional regulator, MarR family FOA56_21040 ENOG4105ERH Fumarylacetoacetate hydrolase FOA56_21045 ENOG4105C26 Dehydrogenase FOA56_21050 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase FOA56_21080 ENOG4105EFA 4-hydroxyphenylacetate FOA56_21085 ENOG4107UWN reductase FOA56_21090 ENOG4105D22 carbon starvation protein FOA56_21095 ENOG4105VCD cytoplasmic protein FOA56_21100 ENOG4105CKI cobalamin synthesis protein FOA56_21110 ENOG4106DIZ Domain of unknown function (DUF1127) FOA56_21115 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOA56_21125 ENOG41083G8 Multidrug resistance protein MdtM FOA56_21130 ENOG4106BRA Membrane FOA56_21135 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FOA56_21140 ENOG4105CIZ coA-substrate-specific enzyme activase FOA56_21155 ENOG4105CBP Major Facilitator FOA56_21165 ENOG41074DU domain protein FOA56_21170 ENOG4108P2H Inner membrane protein YjiG FOA56_21175 ENOG4105DYB Isoaspartyl dipeptidase FOA56_21180 ENOG4107YNJ LysR family Transcriptional regulator FOA56_21200 ENOG4105C6F GntR Family Transcriptional Regulator FOA56_21205 ENOG4105DEI Mannitol dehydrogenase FOA56_21215 ENOG4107EFN gluconate transport system permease 3 FOA56_21220 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin FOA56_21225 ENOG4108T65 Fimbrial FOA56_21230 ENOG4108SQA Fimbrial FOA56_21235 ENOG4105CW0 outer membrane usher protein FOA56_21240 ENOG4108NAE Fimbrial chaperone protein FOA56_21245 ENOG4108S54 Fimbrial protein FOA56_21250 ENOG4108RQP Major type 1 subunit fimbrin FOA56_21255 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off FOA56_21260 ENOG4108W9T type 1 fimbriae regulatory protein FOA56_21265 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria FOA56_21330 ENOG4105DQ4 alcohol dehydrogenase FOA56_21335 ENOG4105D7A ATP-binding protein FOA56_21340 ENOG4108K5H permease YjgP YjgQ family protein FOA56_21345 ENOG4108M8S permease YjgP YjgQ family protein FOA56_21355 ENOG4105MYG DNA polymerase iii, chi subunit FOA56_21360 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FOA56_21365 ENOG4108M3P Membrane FOA56_21370 ENOG4108MJ3 acetyltransferase FOA56_21375 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FOA56_21400 ENOG4105XEP YhcH YjgK YiaL family protein FOA56_21405 ENOG4108XFH Transcriptional regulator FOA56_21410 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FOA56_21415 ENOG4108UQ8 endoribonuclease L-psp FOA56_21420 ENOG41077AM PyrBI operon attenuator FOA56_21435 ENOG4105KME endoribonuclease L-psp FOA56_21440 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FOA56_21450 ENOG4105D4X repressor FOA56_21455 ENOG4105C5Y PTS System FOA56_21460 ENOG4105CG3 alpha amylase, catalytic region FOA56_21465 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOA56_21470 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FOA56_21480 ENOG4105CMS peptidase U62, modulator of DNA gyrase FOA56_21490 ENOG4105DFU Cell wall formation (By similarity) FOA56_21500 ENOG41062B0 ABC transporter, permease FOA56_21505 ENOG4107R9N ABC transporter FOA56_21510 ENOG4105C2J ABC transporter FOA56_21515 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator FOA56_21520 ENOG4105F0N pyrophosphate phospho-hydrolase FOA56_21525 ENOG4105MZG transcriptional modulator of maze toxin, mazf FOA56_21530 ENOG41087RY SpoVT_AbrB FOA56_21535 ENOG4108ZHD aig2 family FOA56_21540 ENOG4105MA0 exported protein FOA56_21545 ENOG4105CFU surface antigen FOA56_21565 ENOG4105C37 (CBS) domain FOA56_21570 ENOG41061GZ Protein of unknown function (DUF1107) FOA56_21575 ENOG4108UUE Transcriptional regulator FOA56_21580 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FOA56_21585 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FOA56_21590 ENOG4105KVH Transcriptional regulator FOA56_21595 ENOG4105ECR NmrA family FOA56_21600 ENOG4105DXC membrane FOA56_21610 ENOG4105C85 amino acid FOA56_21615 ENOG4108V1T peptidylprolyl cis-trans isomerase FOA56_21620 ENOG4105FHY Opacity-associated protein A FOA56_21630 ENOG4105CHR reductase FOA56_21640 ENOG4105E39 Enoyl-CoA hydratase FOA56_21645 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FOA56_21650 ENOG4107S3R L-aspartate oxidase FOA56_21655 ENOG41069H7 transport system small permease component FOA56_21660 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FOA56_21665 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FOA56_21675 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FOA56_21690 ENOG4105KIT UPF0379 protein yjfY FOA56_21715 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport FOA56_21720 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FOA56_21735 ENOG4108MXZ Esterase FOA56_21740 ENOG4105WSB biofilm stress and motility protein A FOA56_21745 ENOG4105S17 UPF0379 protein yjfN FOA56_21750 ENOG4105CSU acyl-Coa dehydrogenase FOA56_21755 ENOG4106032 Glutathionylspermidine synthase FOA56_21760 ENOG4108KXT Conserved Protein FOA56_21765 ENOG4105Z6B inner membrane protein yjfl FOA56_21770 ENOG4107VNS Protein of unknown function (DUF2491) FOA56_21775 ENOG4108P9J Phage shock protein A FOA56_21780 ENOG4105FUX Conserved Protein FOA56_21785 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOA56_21790 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOA56_21810 ENOG4105EPW hflc protein FOA56_21815 ENOG4107QJR hflk protein FOA56_21820 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOA56_21825 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOA56_21840 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOA56_21845 ENOG4105K8N protein family UPF0079, ATPase FOA56_21850 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FOA56_21855 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOA56_21895 ENOG4105EGS Mechanosensitive ion channel FOA56_21900 ENOG4107SC7 Inner membrane transporter yjeM FOA56_21910 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FOA56_21915 ENOG4105E33 succinate dehydrogenase FOA56_21930 ENOG41066YJ Beta-lactamase FOA56_21935 ENOG4105QNF Outer membrane lipoprotein FOA56_21940 ENOG4105KPY Small multidrug resistance protein FOA56_21945 ENOG4106BSU Entericidin B FOA56_21950 ENOG4106HKS Entericidin EcnA/B family FOA56_21960 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOA56_21965 ENOG4105MTB Uncharacterized protein YjeJ FOA56_21970 ENOG4108ZVF (LipO)protein FOA56_21985 ENOG4105DVH amino acid FOA56_21990 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FOA56_21995 ENOG4108IJ0 Aspartate ammonia-lyase FOA56_22000 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOA56_22015 ENOG4108SIC Transcriptional regulator FOA56_22045 ENOG4105F9F transposase FOA56_22170 ENOG4105TS0 gtp-binding protein FOA56_22190 ENOG4106H6R UPF0380 protein FOA56_22195 ENOG4105MFG Antirestriction protein FOA56_22200 ENOG4108YGG dna repair protein FOA56_22205 ENOG4106WJE Protein of unknown function (DUF987) FOA56_22215 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FOA56_22240 ENOG4108M3R transcriptional activator CadC FOA56_22250 ENOG4105D5Q Arginine ornithine antiporter FOA56_22255 ENOG4105CXN decarboxylase FOA56_22260 ENOG4105DUX Transporter FOA56_22265 ENOG4105CRK lysyL-tRNA synthetase FOA56_22280 ENOG410830R acetyltransferase FOA56_22285 ENOG4105VR1 Pfam:DUF1271 FOA56_22290 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOA56_22295 ENOG4108MRH transcriptional regulatory protein FOA56_22300 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOA56_22305 ENOG4107GFK fumarate FOA56_22310 ENOG4108R5S membrane FOA56_22320 ENOG4105CT4 transporter FOA56_22325 ENOG4105F8D glycoside hydrolase family 4 FOA56_22330 ENOG4108K2B transcriptional regulator FOA56_22335 ENOG4105CXN decarboxylase FOA56_22340 ENOG4106ZGR Transcriptional regulator FOA56_22345 ENOG4105D5Q Arginine ornithine antiporter FOA56_22350 ENOG4105DIJ Phosphoethanolamine transferase FOA56_22355 ENOG4105XJC Two component transcriptional regulator (Winged helix family FOA56_22360 ENOG4105ECM Sensor protein basS pmrB FOA56_22370 ENOG4105CSH Transporter FOA56_22375 ENOG4108YIV FOA56_22380 ENOG4108F5E vimentin FOA56_22385 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOA56_22390 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FOA56_22395 ENOG4105D5T phosphonate abc transporter FOA56_22400 ENOG4105EHI Phosphonate ABC transporter, periplasmic FOA56_22410 ENOG4107RJJ Transcriptional regulator FOA56_22415 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG FOA56_22420 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH FOA56_22425 ENOG4105EKV Phosphonate metabolism protein FOA56_22430 ENOG4105FT8 Phosphonate metabolism FOA56_22435 ENOG4105ENV phosphonate C-P lyase system protein PhnK FOA56_22440 ENOG4105HRV phosphonate c-p lyase system protein phnl FOA56_22445 ENOG4105FD8 phosphonate metabolism protein PhnM FOA56_22450 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) FOA56_22455 ENOG410849A acetyltransferase, (GNAT) family FOA56_22460 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein FOA56_22465 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 FOA56_22470 ENOG4108YZG isomerase FOA56_22475 ENOG4105EUZ Beta-lactamase domain protein FOA56_22485 ENOG4105J12 Multidrug resistance protein mdtN FOA56_22490 ENOG4108MI0 Resistance protein FOA56_22495 ENOG4105ETP RND efflux system, outer membrane lipoprotein FOA56_22505 ENOG41082ND Uncharacterized protein yjcO FOA56_22510 ENOG4105CK2 sodium dicarboxylate symporter FOA56_22515 ENOG4108W0S formate-dependent nitrite reductase complex FOA56_22525 ENOG4108QKW cytochrome c-type biogenesis protein FOA56_22530 ENOG4105DVI reductase, NrfD FOA56_22535 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FOA56_22540 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FOA56_22550 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOA56_22555 ENOG41062QD Membrane FOA56_22570 ENOG4105EEQ Na H antiporter FOA56_22575 ENOG4105C7N Xanthine uracil vitamin C permease FOA56_22580 ENOG4108Z4X TRANSCRIPTIONal FOA56_22585 ENOG4108W3Q Transcriptional regulator FOA56_22590 ENOG4108M8H domain protein FOA56_22595 ENOG4105PMV Membrane FOA56_22600 ENOG4108UUM single-stranded DNA-binding protein FOA56_22605 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOA56_22610 ENOG4105MSB protein, conserved in bacteria FOA56_22615 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FOA56_22620 ENOG4105F0S class B acid phosphatase FOA56_22630 ENOG4105CGF Aromatic amino acid aminotransferase FOA56_22635 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOA56_22640 ENOG4105CDU Replicative dna helicase FOA56_22645 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOA56_22650 ENOG4105P4Z Phage shock protein G FOA56_22655 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOA56_22680 ENOG4108X9F tail fiber protein FOA56_22755 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOA56_22790 ENOG4105KUS lysozyme FOA56_22795 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FOA56_22820 ENOG4105HGD Antitermination protein FOA56_22825 ENOG4108MXB Protein of unknown function (DUF968) FOA56_22835 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FOA56_22840 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FOA56_22850 ENOG4105YQ0 FOA56_22860 ENOG4106050 phage regulatory protein, rha family FOA56_22865 ENOG4108S1U FOA56_22895 ENOG4105H40 FOA56_22900 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) FOA56_22905 ENOG4108R7K Metal Dependent Phosphohydrolase FOA56_22910 ENOG41077V0 CPS-53 (KpLE1) prophage FOA56_22955 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOA56_22970 ENOG4105MYN Zinc uptake regulation protein FOA56_22975 ENOG4105VDW Csbd family FOA56_22980 ENOG4107R73 Mate efflux family protein FOA56_22990 ENOG41080IJ Diacylglycerol kinase FOA56_23015 ENOG4107W52 maltose operon periplasmic protein FOA56_23025 ENOG4108IJ9 (ABC) transporter FOA56_23030 ENOG4107FKK extracellular solute-binding protein family 1 FOA56_23035 ENOG4105D56 permease protein FOA56_23040 ENOG4105EG2 ABC transporter, permease FOA56_23045 ENOG4107QNK )-transporter FOA56_23060 ENOG4105E3R (LipO)protein FOA56_23065 ENOG4108Q9C Periplasmic Protein FOA56_23070 ENOG4108MDC (LipO)protein FOA56_23085 ENOG4105CFH Aspartokinase FOA56_23090 ENOG4108WZA zeta toxin FOA56_23095 ENOG410756H nucleotidyltransferase FOA56_23105 ENOG4108ZR5 Conserved Protein FOA56_23110 ENOG4105FE9 pseudouridine synthase FOA56_23115 ENOG4105DKT Transcriptional regulator FOA56_23120 ENOG4105CHR reductase FOA56_23125 ENOG4108XCU pts system FOA56_23130 ENOG4105KPI PTS system sorbose subfamily IIB component FOA56_23135 ENOG4105ETZ PTS System FOA56_23140 ENOG4105F3R pts system mannose fructose sorbose family iid FOA56_23145 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FOA56_23165 ENOG4105EAM Na Pi-cotransporter FOA56_23170 ENOG4105C3R Methionine synthase FOA56_23175 ENOG41069M3 Transcriptional regulator FOA56_23190 ENOG4108I9X Isocitrate lyase FOA56_23195 ENOG4107QP3 malate synthase g FOA56_23205 ENOG4105K5X acetyltransferase FOA56_23235 ENOG4105C12 Phosphoribosylglycinamide synthetase FOA56_23240 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOA56_23245 ENOG4105BZU Histidine kinase FOA56_23250 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism FOA56_23255 ENOG4108T8B Protein of unknown function (DUF1481) FOA56_23260 ENOG4105K70 DNA-binding protein FOA56_23265 ENOG4105R2J Conserved Protein FOA56_23300 ENOG4105D06 uba thif-type nad fad binding protein FOA56_23305 ENOG4105WHD thiamine biosynthesis protein ThiS FOA56_23315 ENOG4105D41 biosynthesis protein thiH FOA56_23320 ENOG410645W Thiamin biosynthesis protein ThiH FOA56_23355 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOA56_23360 ENOG4105PM1 preprotein translocase subunit SecE FOA56_23395 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FOA56_23400 ENOG4105D4A Cell wall formation (By similarity) FOA56_23435 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FOA56_23445 ENOG4108Y73 Membrane FOA56_23450 ENOG4105EJ2 Transcriptional regulator FOA56_23460 ENOG4105C5Q Transcriptional regulator FOA56_23470 ENOG4105CAS nag kinase FOA56_23475 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FOA56_23490 ENOG4105DIJ Phosphoethanolamine transferase FOA56_23495 ENOG4106R3P AraC family transcriptional regulator FOA56_23500 ENOG4108XCZ PTS System FOA56_23505 ENOG4108AHH pyruvate formate lyase II activase FOA56_23510 ENOG4105C6N Formate acetyltransferase FOA56_23515 ENOG4108YRF PTS System FOA56_23520 ENOG4105DM4 PTS System FOA56_23525 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOA56_23530 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOA56_23535 ENOG4105DCT glycerol dehydrogenase FOA56_23540 ENOG4108XC3 NADH ubiquinone oxidoreductase FOA56_23545 ENOG4108Q5Y Membrane FOA56_23550 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) FOA56_23555 ENOG4105SYT Methylenetetrahydrofolate reductase FOA56_23560 ENOG4105CFH Aspartokinase FOA56_23565 ENOG4105C28 cystathionine FOA56_23575 ENOG4107S01 Repressor protein MetJ FOA56_23595 ENOG4105C25 Primosomal protein n' FOA56_23600 ENOG4105ETE Transcriptional regulator (LacI family FOA56_23605 ENOG41063M6 Cell Division Protein FOA56_23620 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOA56_23635 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOA56_23645 ENOG4105CBT Fructose-1,6-bisphosphatase FOA56_23650 ENOG4105DP0 ferredoxin-NADP reductase FOA56_23660 ENOG41065TG regulatoR FOA56_23665 ENOG4108VTS Membrane FOA56_23670 ENOG4105EBK exported protein FOA56_23685 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FOA56_23700 ENOG4105FMW periplasmic FOA56_23705 ENOG4105E3W Two component transcriptional regulator (Winged helix family FOA56_23710 ENOG4105E0F Histidine kinase FOA56_23715 ENOG4108RPX mosc domain containing protein FOA56_23725 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOA56_23755 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) FOA56_23765 ENOG41064BA PTS system, fructose-specific, IIA component FOA56_23770 ENOG4105DM4 PTS System FOA56_23775 ENOG4105CN9 Peptidase m42 family protein FOA56_23780 ENOG4106C3V frv operon regulatory protein FOA56_23785 ENOG4108V87 frv operon regulatory protein FOA56_23800 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FOA56_23805 ENOG4108MG3 formate dehydrogenase FOA56_23815 ENOG41068KX affects formate dehydrogenase-N FOA56_23820 ENOG4106UEE Transcriptional regulator FOA56_23830 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system FOA56_23840 ENOG4105SUU thioesterase domain FOA56_23855 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FOA56_23860 ENOG4105E98 transcriptional regulator DeoR family FOA56_23865 ENOG4108MGF sugar kinase FOA56_23870 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOA56_23875 ENOG4105D2M Aldolase FOA56_23880 ENOG4107QKS N-acylglucosamine 2-epimerase FOA56_23885 ENOG4107WI4 Aldose-1-epimerase FOA56_23890 ENOG4105CJQ hydrolase, family 31 FOA56_23895 ENOG4105CT4 transporter FOA56_23900 ENOG4105CT4 transporter FOA56_23905 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is FOA56_23910 ENOG4105R9B Major Facilitator FOA56_23915 ENOG4108KHF Resistance protein FOA56_23920 ENOG4108K85 Transcriptional regulator FOA56_23930 ENOG4105C5F glutamine synthetase FOA56_23935 ENOG4105CUX Signal transduction histidine kinase FOA56_23940 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOA56_23945 ENOG4106FIY FOA56_23950 ENOG4105D4P Coproporphyrinogen iii oxidase FOA56_23965 ENOG4105C2M dna polymerase I FOA56_23975 ENOG4106HNH Acyl-transferase FOA56_23985 ENOG4108Z33 Thiol disulfide Interchange Protein FOA56_23990 ENOG4105E27 serine threonine protein kinase FOA56_23995 ENOG4105PC1 Conserved Protein FOA56_24000 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FOA56_24005 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FOA56_24035 ENOG4108RR8 protoporphyrinogen oxidase FOA56_24040 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FOA56_24045 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOA56_24065 ENOG4107QK7 reductase FOA56_24070 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FOA56_24075 ENOG4105MDZ Transcriptional activator rfaH FOA56_24085 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOA56_24090 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FOA56_24095 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FOA56_24105 ENOG4105JC1 sterol-binding domain protein FOA56_24115 ENOG4105CGY Dna recombination protein FOA56_24120 ENOG4108I5U Uridine phosphorylase FOA56_24125 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FOA56_24135 ENOG4105DZ2 Transcriptional regulator FOA56_24140 ENOG4105EMK carboxylate amino acid amine transporter FOA56_24145 ENOG4105DQF Hydrolase FOA56_24150 ENOG4108EUD Lysophospholipase FOA56_24165 ENOG4105C9U ATP-dependent DNA helicase RecQ FOA56_24170 ENOG4105HDD phospholipase FOA56_24175 ENOG4108VUY thioesterase Superfamily protein FOA56_24180 ENOG4105FR1 rard protein FOA56_24185 ENOG4106WR8 Inner membrane protein YigG FOA56_24190 ENOG4105NRM Membrane FOA56_24195 ENOG4107QUT magnesium and cobalt transport protein CorA FOA56_24200 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase FOA56_24205 ENOG4105C4R Atp-dependent dna helicase FOA56_24210 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FOA56_24220 ENOG4105CT0 Protein of unknown function, DUF484 FOA56_24230 ENOG4105S7Z (LipO)protein FOA56_24240 ENOG4107T0K Adenylate cyclase FOA56_24250 ENOG41076E6 Uroporphyrinogen-III Synthase FOA56_24255 ENOG4105ECF c-methyltransferase FOA56_24260 ENOG410601J HemY protein FOA56_24265 ENOG4105C4X radical SAM domain protein FOA56_24290 ENOG4105C85 amino acid FOA56_24310 ENOG4105EGZ biosynthesis protein FOA56_24315 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FOA56_24320 ENOG4108WJ1 acetyltransferase FOA56_24325 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOA56_24330 ENOG4105C1B dTDP-glucose 4-6-dehydratase FOA56_24335 ENOG4108IJ1 Dehydrogenase FOA56_24340 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOA56_24345 ENOG4105SFE lipopolysaccharide biosynthesis protein FOA56_24350 ENOG4105ESV Glycosyl transferase, family 4 FOA56_24365 ENOG4105K63 Thioredoxin FOA56_24380 ENOG4105C4R Atp-dependent dna helicase FOA56_24390 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FOA56_24400 ENOG4105EMY transcriptional regulator FOA56_24405 ENOG4105C7B Threonine dehydratase FOA56_24415 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOA56_24420 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FOA56_24440 ENOG4105C0P Mg chelatase subunit ChlI FOA56_24445 ENOG4108WFC UPF0438 protein yifE FOA56_24485 ENOG4107EJG GntR family transcriptional regulator FOA56_24490 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOA56_24495 ENOG4105ETE Transcriptional regulator (LacI family FOA56_24500 ENOG4108RVA ribokinase FOA56_24505 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOA56_24510 ENOG4105CNN ABC, transporter FOA56_24515 ENOG4105C2J ABC transporter FOA56_24535 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FOA56_24545 ENOG4108VVK transcriptional Regulator, AsnC FOA56_24550 ENOG4105QTB Flavodoxin FOA56_24565 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FOA56_24575 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FOA56_24620 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FOA56_24635 ENOG4105CW0 outer membrane usher protein FOA56_24645 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FOA56_24650 ENOG4105C8U phosphate abc transporter FOA56_24655 ENOG4105E2Z phosphate ABC transporter (Permease FOA56_24660 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FOA56_24665 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOA56_24670 ENOG4105CID antiterminator FOA56_24675 ENOG4105C5Y PTS System FOA56_24680 ENOG4105CS2 ec 3.2.1.21 FOA56_24690 ENOG4105DYC esterase FOA56_24695 ENOG4107VKM 6-phosphogluconolactonase FOA56_24700 ENOG4106611 bacteriocin immunity FOA56_24710 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FOA56_24715 ENOG4105C7N Xanthine uracil vitamin C permease FOA56_24720 ENOG4108YYH Nadph-dependent fmn reductase FOA56_24725 ENOG4105E8Q phosphopantetheinyl transferase FOA56_24740 ENOG4108P6C Tryptophan transporter of low affinity FOA56_24945 ENOG41073YN Protein of unknown function (DUF1380) FOA56_24995 ENOG4105FEQ ParB domain protein nuclease FOA56_25205 ENOG4105CZX twitching motility protein FOA56_25260 ENOG4105K5T PilT protein FOA56_25275 ENOG4107QHF type ii secretion system protein e