locus-tag class description ECTO73_00002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ECTO73_00004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ECTO73_00005 ENOG4105VP5 Bacterial protein of unknown function (DUF937) ECTO73_00006 ENOG410667J hydrolase ECTO73_00007 ENOG410657R replicase EC 2.7 ECTO73_00008 ENOG4105EMF GntR family transcriptional regulator ECTO73_00009 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 ECTO73_00010 ENOG4108RTU Aldolase ECTO73_00012 ENOG4105DJB Major Facilitator Superfamily ECTO73_00013 ENOG4107WAP fad NAD(P)-binding domain ECTO73_00014 ENOG4105D99 atp gtp-binding protein ECTO73_00015 ENOG4105R2A (LipO)protein ECTO73_00020 ENOG4105FDP GntR family transcriptional regulator ECTO73_00021 ENOG4105CI1 PTS System ECTO73_00023 ENOG4105F8D glycoside hydrolase family 4 ECTO73_00024 ENOG4108AHD Transcriptional regulator ECTO73_00025 ENOG4107RUZ Sss sodium solute transporter superfamily ECTO73_00026 ENOG4105CBG Sulfatase ECTO73_00027 ENOG4106DRA Inner membrane protein YidI ECTO73_00028 ENOG4105VG5 Membrane ECTO73_00029 ENOG4105JP4 Inner membrane protein yidG ECTO73_00030 ENOG4105J13 transcriptional regulator ECTO73_00031 ENOG4105E5M Multidrug resistance protein D ECTO73_00035 ENOG4105C7K acetolactate synthase ECTO73_00036 ENOG4105M71 acetolactate synthase 1 regulatory subunit ECTO73_00037 ENOG4108KX4 response regulator ECTO73_00038 ENOG4105BZU Histidine kinase ECTO73_00039 ENOG4105CXY transporter ECTO73_00040 ENOG4105CXY transporter ECTO73_00042 ENOG4105C7N Xanthine uracil vitamin C permease ECTO73_00043 ENOG4108SAJ Protein of unknown function (DUF1198) ECTO73_00045 ENOG4105T8A Uncharacterized protein YicS ECTO73_00046 ENOG4105D01 (LipO)protein ECTO73_00047 ENOG4108UZ3 Transporter ECTO73_00048 ENOG4105S8Q sugar efflux transporter ECTO73_00050 ENOG4105CT4 transporter ECTO73_00051 ENOG4105CJQ hydrolase, family 31 ECTO73_00052 ENOG4105JV1 AsmA family ECTO73_00053 ENOG4105C2W permease ECTO73_00054 ENOG4105D6U Sodium Glutamate Symporter ECTO73_00055 ENOG4105CB5 ATP-dependent DNA helicase recG ECTO73_00056 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase ECTO73_00057 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ECTO73_00058 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) ECTO73_00059 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) ECTO73_00060 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) ECTO73_00061 ENOG4105EN6 Membrane ECTO73_00062 ENOG4105F5P DNA-damage-inducible protein d ECTO73_00063 ENOG4105DSJ YicC domain protein ECTO73_00068 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ECTO73_00071 ENOG4105W0E 50S ribosomal protein L33 ECTO73_00074 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase ECTO73_00076 ENOG4105DKP glycosyl transferase, family 9 ECTO73_00077 ENOG4107RJ7 Glycosyl transferase (Group 1 ECTO73_00078 ENOG4107543 (lipo)polysaccharide ECTO73_00079 ENOG4105X1N Glycosyl transferase family 8 ECTO73_00080 ENOG4107XU6 Glycosyl transferase (Group 1 ECTO73_00081 ENOG4106AH0 Glycosyl Transferase ECTO73_00082 ENOG4105X1N Glycosyl transferase family 8 ECTO73_00083 ENOG4108PDR lipopolysaccharide core biosynthesis protein ECTO73_00084 ENOG4108QD8 lipopolysaccharide core biosynthesis protein ECTO73_00085 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase ECTO73_00086 ENOG4108FRV O-antigen ligase ECTO73_00087 ENOG4105D16 lipopolysaccharide heptosyltransferase i ECTO73_00088 ENOG4105XA0 heptosyltransferase ii ECTO73_00090 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ECTO73_00092 ENOG4105K64 Glycosyl transferase, family 2 ECTO73_00093 ENOG4105PXI polysaccharide deacetylase ECTO73_00094 ENOG41063SB peptidase ECTO73_00096 ENOG4107YZP Rhodanese domain protein ECTO73_00097 ENOG4105VW4 glutaredoxin 3 ECTO73_00100 ENOG4105D7W serine acetyltransferase ECTO73_00101 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ECTO73_00103 ENOG41073TP transcriptional regulator ECTO73_00104 ENOG4105DAA L-lactate ECTO73_00105 ENOG4108YYI Protein of unknown function (DUF2810) ECTO73_00107 ENOG4105E61 Mannitol repressor protein ECTO73_00109 ENOG4105CTS PTS system mannitol-specific ECTO73_00110 ENOG4105FP6 Protein of unknown function (DUF3302) ECTO73_00111 ENOG4105EFX secretion protein, HlyD family ECTO73_00114 ENOG4105NUP lyase containing HEAT-repeat ECTO73_00115 ENOG4105CNA YD repeat protein ECTO73_00116 ENOG4108U78 Glutathione S-transferase ECTO73_00118 ENOG4105EM7 Selenocysteine-specific translation elongation factor ECTO73_00119 ENOG4105C0A alcohol dehydrogenase ECTO73_00120 ENOG4105C26 Dehydrogenase ECTO73_00122 ENOG4105KK7 inner membrane protein YiaW ECTO73_00123 ENOG4105EFX secretion protein, HlyD family ECTO73_00124 ENOG4108Q2M Transcriptional regulator ECTO73_00125 ENOG4105GNX MltA-interacting MipA family protein ECTO73_00126 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase ECTO73_00127 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase ECTO73_00128 ENOG4105H6Q decarboxylase ECTO73_00129 ENOG4105CMG Carbohydrate kinase ECTO73_00130 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit ECTO73_00131 ENOG4105CG6 trap dicarboxylate transporter dctm subunit ECTO73_00132 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter ECTO73_00133 ENOG4108R66 Conserved Protein ECTO73_00135 ENOG4105J4Q Transcriptional regulator ECTO73_00136 ENOG4108XIB electron transport protein ysaA ECTO73_00137 ENOG4105JKW Valine--pyruvate aminotransferase ECTO73_00138 ENOG4107T9C Alpha amylase catalytic region ECTO73_00139 ENOG4108UR8 BAX protein ECTO73_00140 ENOG4105T16 Transcriptional regulator (AraC family) ECTO73_00141 ENOG4107RNG ABC transporter ECTO73_00142 ENOG4105C2J ABC transporter ECTO73_00143 ENOG4105DFW ABC transporter ECTO73_00145 ENOG4105CMG Carbohydrate kinase ECTO73_00146 ENOG410688U Inner membrane protein yiaB ECTO73_00147 ENOG4108Z12 YiaAB two helix domain-containing protein ECTO73_00148 ENOG4105MEV Acyl-transferase ECTO73_00149 ENOG4105RGS lipoprotein ysaB ECTO73_00150 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit ECTO73_00153 ENOG4105DQ6 Transposase ECTO73_00154 ENOG410698F IS150 protein InsA ECTO73_00155 ENOG41060TC Hok gef cell toxic protein ECTO73_00157 ENOG4105VEQ Cold shock protein ECTO73_00158 ENOG4105MVF Transcriptional regulator ECTO73_00159 ENOG4106JH6 (LipO)protein ECTO73_00161 ENOG4108ZG0 Ompa motb domain protein ECTO73_00162 ENOG4107QY8 reductase ECTO73_00163 ENOG4105HNP -acetyltransferase ECTO73_00164 ENOG4108R3E Dna-3-methyladenine glycosylase i ECTO73_00165 ENOG4105EAX Putative lipase ECTO73_00166 ENOG4105FCD Major Facilitator ECTO73_00167 ENOG4105DIJ Phosphoethanolamine transferase ECTO73_00170 ENOG4105DEF Extracellular solute-binding protein, family 5 ECTO73_00171 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ECTO73_00172 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ECTO73_00173 ENOG4105C3U ABC transporter ECTO73_00174 ENOG4108JQ7 (ABC) transporter ECTO73_00175 ENOG4105C44 Serine transporter ECTO73_00178 ENOG4105D1V cellulose synthase operon protein YhjU ECTO73_00179 ENOG4105WQA Cellulose biosynthesis protein BcsF ECTO73_00180 ENOG4105U74 cellulose biosynthesis protein BcsE ECTO73_00181 ENOG410661M cytoplasmic protein ECTO73_00184 ENOG4107QZ7 Cellulose synthase catalytic subunit ECTO73_00185 ENOG4107QZ7 Cellulose synthase catalytic subunit ECTO73_00186 ENOG4107EEX Cellulose synthase regulator protein ECTO73_00187 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) ECTO73_00188 ENOG4105EJG cellulose synthase ECTO73_00189 ENOG4105BZU Histidine kinase ECTO73_00191 ENOG4105CS0 peptidase ECTO73_00192 ENOG4107SS6 2-dehydro-3-deoxygluconokinase ECTO73_00193 ENOG4105CMB EAL domain-containing protein ECTO73_00194 ENOG41066T0 asmA family ECTO73_00195 ENOG4105CSH Transporter ECTO73_00196 ENOG4107H3J ribonuclease ECTO73_00197 ENOG4105CBN LysR family transcriptional regulator ECTO73_00198 ENOG4106S2D Transcriptional regulator ECTO73_00199 ENOG4105E53 ec 3.2.1.28 ECTO73_00200 ENOG4105CA0 peroxidase ECTO73_00201 ENOG4105CVK Glutamate decarboxylase ECTO73_00202 ENOG4108NKV transcriptional regulator ECTO73_00204 ENOG4105D3F AraC Family Transcriptional Regulator ECTO73_00205 ENOG4105BZS acriflavin resistance protein ECTO73_00206 ENOG4105C1P efflux transporter, rnd family, mfp subunit ECTO73_00208 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci ECTO73_00209 ENOG4108YK4 Acid-resistance membrane protein ECTO73_00210 ENOG41060V2 Acid-resistance protein ECTO73_00211 ENOG4105XXV Acid-resistance protein ECTO73_00212 ENOG4105KT7 mgtC SapB transporter ECTO73_00214 ENOG4105Y4Z Outer Membrane Lipoprotein ECTO73_00216 ENOG4105K89 arsenate reductase ECTO73_00217 ENOG4107R5R arsenical pump membrane protein ECTO73_00218 ENOG4105KBH arsR family transcriptional regulator ECTO73_00220 ENOG4105DC8 reductase ECTO73_00221 ENOG4105D6S protein involved in catabolism of external DNA ECTO73_00222 ENOG4105DGW oligopeptidase A ECTO73_00223 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) ECTO73_00224 ENOG4105DUX Transporter ECTO73_00225 ENOG4108M6U Universal stress protein A ECTO73_00227 ENOG4105CJ3 phosphate transporter ECTO73_00228 ENOG4105CBX hi0933 family ECTO73_00229 ENOG4107UNS conserved inner membrane protein ECTO73_00232 ENOG4105D0S secretion protein (HlyD ECTO73_00233 ENOG4105CJ1 ABC, transporter ECTO73_00234 ENOG4105CMI transporter ECTO73_00235 ENOG410600T transposase ECTO73_00236 ENOG4105NUP lyase containing HEAT-repeat ECTO73_00238 ENOG4105CNA YD repeat protein ECTO73_00240 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) ECTO73_00241 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) ECTO73_00242 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ECTO73_00243 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ECTO73_00244 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein ECTO73_00245 ENOG4107YAK holo-(acyl carrier protein) synthase 2 ECTO73_00246 ENOG4105DSF transport protein ECTO73_00247 ENOG4105F9N Major Facilitator Superfamily ECTO73_00248 ENOG4108W1V Lipoprotein ECTO73_00249 ENOG4105EX9 Membrane ECTO73_00251 ENOG4105C59 p-type ATPase ECTO73_00252 ENOG4107FS9 Membrane ECTO73_00254 ENOG4105MG3 Membrane ECTO73_00255 ENOG4106H78 methyltransferase ECTO73_00256 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ECTO73_00257 ENOG4105CAK Cell division ATP-binding protein ftsE ECTO73_00258 ENOG4105CRP Part of the ABC transporter FtsEX involved in ECTO73_00259 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ECTO73_00260 ENOG4105CP9 extracellular ligand-binding receptor ECTO73_00261 ENOG4105U59 -acetyltransferase ECTO73_00262 ENOG4105CP9 extracellular ligand-binding receptor ECTO73_00263 ENOG4105C32 Amino acid ABC transporter (Permease) ECTO73_00264 ENOG4105CF8 branched-chain amino acid ABC transporter, permease ECTO73_00265 ENOG4105C0Z ABC transporter ECTO73_00266 ENOG4108IV0 ABC, transporter ECTO73_00267 ENOG4105BZ7 extracellular solute-binding protein family 1 ECTO73_00268 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component ECTO73_00269 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component ECTO73_00270 ENOG4108IJ9 (ABC) transporter ECTO73_00271 ENOG4107T6V glycerophosphoryl diester phosphodiesterase ECTO73_00272 ENOG4105WC8 Conserved Protein ECTO73_00273 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ECTO73_00274 ENOG4106FA4 ECTO73_00277 ENOG4105GMB type VI secretion system effector, hcp1 family ECTO73_00278 ENOG4105WCN acetyltransferase ECTO73_00280 ENOG4105D9R oxidoreductase ECTO73_00281 ENOG4105C2I pirin domain protein ECTO73_00282 ENOG4105DIQ Transcriptional regulator ECTO73_00283 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family ECTO73_00284 ENOG4105C6Z Gluconate ECTO73_00285 ENOG41076UM multiple antibiotic resistance (MarC)-related protein ECTO73_00286 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ECTO73_00291 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) ECTO73_00293 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ECTO73_00296 ENOG4105E98 transcriptional regulator DeoR family ECTO73_00297 ENOG4105CYB regulatoR ECTO73_00298 ENOG4105E0Y RtcB Protein ECTO73_00301 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) ECTO73_00302 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) ECTO73_00303 ENOG4105C6Z Gluconate ECTO73_00305 ENOG4105MJ2 Competence protein ECTO73_00307 ENOG4105DNE Transposase ECTO73_00309 ENOG4105CE1 Ferrous iron transport protein b ECTO73_00310 ENOG4105XFK Ferrous iron transport protein A ECTO73_00311 ENOG4105BZM domain protein ECTO73_00312 ENOG4108RRZ Transcription elongation factor GreB ECTO73_00313 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ECTO73_00314 ENOG4105E0F Histidine kinase ECTO73_00316 ENOG4108MAJ Membrane ECTO73_00318 ENOG4105VEJ Heat shock protein ECTO73_00319 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 ECTO73_00320 ENOG4105DQY intracellular growth attenuator ECTO73_00321 ENOG4107RK2 ADP-ribose diphosphatase NudE ECTO73_00322 ENOG4108JQC penicillin-binding protein 1A ECTO73_00323 ENOG4108U1Q Pilus assembly protein ECTO73_00324 ENOG41065NF Fimbrial assembly family protein ECTO73_00325 ENOG4105XPX DNA utilization protein HofO ECTO73_00326 ENOG4105ITY Required for the use of extracellular DNA as a nutrient ECTO73_00327 ENOG4105E4G Type IV pilus ECTO73_00330 ENOG4105EGB membrane protein DamX ECTO73_00331 ENOG4105DFE Dna adenine methylase ECTO73_00332 ENOG4105DJV ribulose-phosphate 3-epimerase ECTO73_00333 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) ECTO73_00334 ENOG4105C31 Tryptophanyl-tRNA synthetase ECTO73_00335 ENOG4108M21 ECTO73_00336 ENOG4105RMW regulation of transcription, DNA-dependent ECTO73_00337 ENOG4108626 Racemase ECTO73_00338 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) ECTO73_00339 ENOG41080QX K07048 phosphotriesterase-related protein ECTO73_00340 ENOG4105MUZ Protein of unknown function DUF2620 ECTO73_00341 ENOG4106M0N transport system permease protein ECTO73_00342 ENOG4106PKC pyridoxal phosphate binding ECTO73_00343 ENOG4105FDP GntR family transcriptional regulator ECTO73_00344 ENOG4108KPW sugar kinase ECTO73_00345 ENOG4107Y0V Not clear, may be involved in an isomerization step ECTO73_00346 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine ECTO73_00347 ENOG4107QHQ amino acid ECTO73_00348 ENOG4105VYH ECTO73_00350 ENOG4107V9H nitrite transporter ECTO73_00351 ENOG4105WZK nitrite reductase NADPH small subunit ECTO73_00352 ENOG4107QZF nitrite reductase NADPH large subunit ECTO73_00354 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ECTO73_00355 ENOG4106195 uncharacterized protein yhfG ECTO73_00356 ENOG4105MZU cell filamentation protein ECTO73_00357 ENOG4105DDQ anthranilate synthase ECTO73_00358 ENOG4105C8Y Acetylornithine aminotransferase ECTO73_00359 ENOG410613R integral membrane protein, YccS YhfK family ECTO73_00360 ENOG4107RYR Transcriptional regulator, Crp Fnr family ECTO73_00361 ENOG4108UKZ OsmC family ECTO73_00362 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) ECTO73_00364 ENOG4105DNZ Alpha Beta Hydrolase ECTO73_00365 ENOG4105C5H ABC transporter ECTO73_00368 ENOG4105VKU nucleicacid-binding protein ECTO73_00369 ENOG4108YZY peptidylprolyl cis-trans isomerase ECTO73_00371 ENOG4108V1T peptidylprolyl cis-trans isomerase ECTO73_00372 ENOG4105WWK YheO domain protein ECTO73_00380 ENOG4108NNZ chitinase ECTO73_00381 ENOG4105W53 bacterioferritin-associated ferredoxin ECTO73_00382 ENOG4108UQY Iron-storage protein ECTO73_00383 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) ECTO73_00385 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) ECTO73_00386 ENOG4105R04 type II secretion system protein K ECTO73_00389 ENOG41069X0 general secretion pathway protein h ECTO73_00390 ENOG4108VAU general secretion pathway protein G ECTO73_00391 ENOG4105D7Q type ii secretion system ECTO73_00392 ENOG4107QHF type ii secretion system protein e ECTO73_00393 ENOG4105GVR general secretion pathway protein D ECTO73_00394 ENOG4107KSE General secretion pathway protein C ECTO73_00395 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression ECTO73_00396 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication ECTO73_00399 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) ECTO73_00400 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) ECTO73_00402 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) ECTO73_00403 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) ECTO73_00404 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) ECTO73_00405 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) ECTO73_00407 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal ECTO73_00409 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) ECTO73_00412 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) ECTO73_00414 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) ECTO73_00415 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) ECTO73_00418 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ECTO73_00419 ENOG41067V7 50S ribosomal protein L36 ECTO73_00421 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits ECTO73_00423 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) ECTO73_00424 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ECTO73_00426 ENOG4105VTS DnaJ-like, subfamily C ECTO73_00427 ENOG4105W1Y Transcriptional regulator ECTO73_00428 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system ECTO73_00430 ENOG4105C1A potassium transporter peripheral membrane ECTO73_00434 ENOG4105C79 DNA protecting protein DprA ECTO73_00436 ENOG4108WI1 Dna topoisomerase ECTO73_00437 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ECTO73_00439 ENOG4105SG3 Protein of unknown function (DUF1488) ECTO73_00440 ENOG4108Z0R Transferase ECTO73_00449 ENOG4105CDA abc transporter atp-binding protein ECTO73_00450 ENOG4105DRP amino acid AbC transporter ECTO73_00451 ENOG4105EZ7 amino acid ABC transporter ECTO73_00453 ENOG4105XCM membrane LIPOPROTEIN ECTO73_00455 ENOG4105BZS acriflavin resistance protein ECTO73_00456 ENOG4105C1P efflux transporter, rnd family, mfp subunit ECTO73_00457 ENOG4108XG4 DNA-binding transcriptional regulator ECTO73_00458 ENOG41061ME transport protein ECTO73_00459 ENOG4105CEC DNA methylase N-4 N-6 ECTO73_00460 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) ECTO73_00461 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ECTO73_00463 ENOG4108IA2 Sodium pantothenate symporter ECTO73_00464 ENOG4105RG0 Membrane ECTO73_00465 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ECTO73_00466 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein ECTO73_00467 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family ECTO73_00468 ENOG41062P1 Diguanylate cyclase phosphodiesterase ECTO73_00469 ENOG4105DFF Rod shape-determining protein mreb ECTO73_00470 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ECTO73_00471 ENOG4105VQ7 Rod shape-determining protein MreD ECTO73_00472 ENOG4108Z03 MAF-like protein ECTO73_00473 ENOG4105C03 ribonuclease ECTO73_00474 ENOG4105QD6 exported protein ECTO73_00475 ENOG4105D1U peptidase U62 modulator of DNA gyrase ECTO73_00476 ENOG4105CR8 Transcriptional regulator ECTO73_00480 ENOG4105UNR (Barnase) inhibitor ECTO73_00481 ENOG4105RID UPF0379 protein yhcN ECTO73_00484 ENOG4105C0H protease ECTO73_00485 ENOG4105C0H protease ECTO73_00486 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III ECTO73_00487 ENOG4105D6Z AFG1 family ATPase ECTO73_00489 ENOG4108UJD 30S ribosomal protein S9 ECTO73_00490 ENOG4107MKT Stringent starvation protein a ECTO73_00491 ENOG4105KB2 stringent starvation protein b ECTO73_00492 ENOG4105CEE C4-dicarboxylate transporter ECTO73_00498 ENOG4108R66 Conserved Protein ECTO73_00499 ENOG4105DFS Conserved Protein ECTO73_00500 ENOG4105UMR response to DNA damage stimulus ECTO73_00502 ENOG4105E6S usher protein( ECTO73_00503 ENOG4108S1B Periplasmic chaperone protein ECTO73_00505 ENOG4106AJS Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon ECTO73_00506 ENOG4105BZ8 glutamate synthase ECTO73_00507 ENOG4105CBC glutamate synthase ECTO73_00508 ENOG4105N5T Radical SAM Protein ECTO73_00509 ENOG4105BZU Histidine kinase ECTO73_00511 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain ECTO73_00513 ENOG4108NIH transferase activity, transferring phosphorus-containing groups ECTO73_00514 ENOG41080Z8 PHOSPHOCARRIER protein ECTO73_00516 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN ECTO73_00517 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA ECTO73_00518 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ECTO73_00519 ENOG4108IUZ ABC transporter ECTO73_00520 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA ECTO73_00521 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) ECTO73_00522 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase ECTO73_00523 ENOG4105C2X Arabinose 5-phosphate isomerase ECTO73_00524 ENOG4105FEU K -dependent Na -Ca exchanger ECTO73_00525 ENOG4105DHJ ABC, transporter ECTO73_00526 ENOG4105CY3 ABC transporter, permease ECTO73_00527 ENOG4107PE3 Mammalian cell entry related domain protein ECTO73_00528 ENOG4105E3I toluene tolerance ECTO73_00529 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane ECTO73_00530 ENOG4105VFK BolA family ECTO73_00532 ENOG4105HVQ Regulatory factor of maltose metabolism ECTO73_00533 ENOG4105EAH synthase ECTO73_00536 ENOG4105QYV Membrane ECTO73_00537 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control ECTO73_00538 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase ECTO73_00540 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) ECTO73_00541 ENOG4105HBR Rna-binding protein ECTO73_00542 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) ECTO73_00543 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ECTO73_00544 ENOG4105EEI dihydropteroate synthase ECTO73_00548 ENOG4105DIJ Phosphoethanolamine transferase ECTO73_00553 ENOG4105CHV Transcription elongation factor NusA ECTO73_00556 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) ECTO73_00561 ENOG4105RT1 May be involved in cell division (By similarity) ECTO73_00562 ENOG4105C1J atp-dependent rna helicase ECTO73_00563 ENOG4105CIC tryptophan-specific transport protein ECTO73_00564 ENOG4105DEN Luciferase family ECTO73_00565 ENOG4106RZ4 Peptidase U32 ECTO73_00566 ENOG4105CFP Peptidase U32 ECTO73_00567 ENOG4105XPQ lipid carrier protein ECTO73_00568 ENOG4108YYD acetyltransferase ECTO73_00571 ENOG4107R7Y intracellular protease Pfpi family ECTO73_00572 ENOG4105K4T epimerase ECTO73_00573 ENOG4107S21 permease ECTO73_00574 ENOG4105W4M Transport-associated protein ECTO73_00575 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) ECTO73_00577 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) ECTO73_00578 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ECTO73_00579 ENOG4105I74 Fimbrial protein ECTO73_00580 ENOG4105CW0 outer membrane usher protein ECTO73_00581 ENOG4108VCD Chaperone ECTO73_00582 ENOG4105Q10 Fimbrial-like protein ECTO73_00583 ENOG4106HBN Galactosamine-6-phosphate isomerase ECTO73_00584 ENOG4105F3R pts system mannose fructose sorbose family iid ECTO73_00585 ENOG4105ETZ PTS System ECTO73_00588 ENOG4105ETZ PTS System ECTO73_00589 ENOG4108UZY PTS System ECTO73_00591 ENOG4105E70 isomerase ECTO73_00592 ENOG4105CE4 GlcNAc 6-P deacetylase ECTO73_00593 ENOG4108YTN IIa component ECTO73_00594 ENOG4105F3R pts system mannose fructose sorbose family iid ECTO73_00596 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB ECTO73_00598 ENOG4105E98 transcriptional regulator DeoR family ECTO73_00599 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression ECTO73_00600 ENOG4105ZEG Suppressor protein ECTO73_00601 ENOG4105CTX dehydratase ECTO73_00602 ENOG4105DJB Major Facilitator Superfamily ECTO73_00604 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ECTO73_00605 ENOG4105BZW Glycerate kinase ECTO73_00609 ENOG410811B TRANSCRIPTIONal ECTO73_00610 ENOG4105C7B Threonine dehydratase ECTO73_00612 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ECTO73_00613 ENOG4105C6N Formate acetyltransferase ECTO73_00614 ENOG4105KME endoribonuclease L-psp ECTO73_00615 ENOG4105EJQ L-serine dehydratase ECTO73_00616 ENOG4105C44 Serine transporter ECTO73_00618 ENOG4106D80 Uncharacterized protein YhaL ECTO73_00619 ENOG4108CNN domain protein ECTO73_00620 ENOG4105CWB LysR family transcriptional Regulator ECTO73_00621 ENOG4105KAF membrAne ECTO73_00622 ENOG4105KAF membrAne ECTO73_00623 ENOG4105CHF Glutathione S-transferase ECTO73_00624 ENOG4108VBZ doxx family ECTO73_00625 ENOG4105YJD ECTO73_00626 ENOG41090KG Inner membrane protein YqjE ECTO73_00627 ENOG4105NE1 Conserved Protein ECTO73_00628 ENOG4105WAY exported protein ECTO73_00629 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) ECTO73_00630 ENOG4106W5V Membrane ECTO73_00631 ENOG4107YCY Transcriptional regulator ECTO73_00632 ENOG4105DPW Major facilitator superfamily MFS_1 ECTO73_00634 ENOG4105CTX dehydratase ECTO73_00635 ENOG4105P66 Membrane ECTO73_00636 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) ECTO73_00637 ENOG4105DU1 integral membrane protein, terc ECTO73_00639 ENOG4105EE0 oxidoreductase ECTO73_00640 ENOG4108UB4 uncharacterized protein ygjQ ECTO73_00641 ENOG4108VKG metal-dependent hydrolase ECTO73_00642 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) ECTO73_00643 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase ECTO73_00644 ENOG4108Z3N Transcriptional regulator ECTO73_00645 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ECTO73_00646 ENOG4107WCA isomerase ECTO73_00647 ENOG4107W6W Conserved Protein ECTO73_00648 ENOG4105E5D amino acid ECTO73_00649 ENOG4105FK9 beta-D-galactosidase beta subunit ECTO73_00650 ENOG4105CNT hydrolase family 2 ECTO73_00651 ENOG4105CQ4 Transcriptional regulator ECTO73_00652 ENOG4108Y51 tRNA-binding protein ECTO73_00654 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor ECTO73_00655 ENOG4105NTW Transcriptional regulator ECTO73_00656 ENOG4105Q26 Siderophore-interacting protein ECTO73_00659 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ECTO73_00660 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ECTO73_00661 ENOG4105VCC 30S ribosomal protein S21 ECTO73_00663 ENOG4107QPK )-transporter ECTO73_00664 ENOG4107GFK fumarate ECTO73_00665 ENOG4106DSS Tartrate dehydratase subunit alpha ECTO73_00666 ENOG4105EJC lysr family transcriptional regulator ECTO73_00668 ENOG4107ZVW dihydroneopterin aldolase ECTO73_00669 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) ECTO73_00671 ENOG4106MWK domain protein ECTO73_00672 ENOG4105I7R Adenylate cyclase ECTO73_00677 ENOG4107S78 Band 7 protein ECTO73_00678 ENOG4105PV3 Inner membrane protein yqiJ ECTO73_00680 ENOG4108MY7 Fimbrial ECTO73_00681 ENOG4108TTM chaperone ECTO73_00683 ENOG4105H8W Fimbrial protein ECTO73_00684 ENOG4105W0Z cytoplasmic protein ECTO73_00689 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b ECTO73_00690 ENOG4106032 Glutathionylspermidine synthase ECTO73_00692 ENOG4105DFG type I secretion outer membrane protein ECTO73_00693 ENOG41087AY ADP-Ribose pyrophosphatase ECTO73_00694 ENOG4108SX3 cytoplasmic protein ECTO73_00695 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ECTO73_00696 ENOG4105IPS esterase ECTO73_00697 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ECTO73_00698 ENOG4105VRH Antibiotic biosynthesis monooxygenase ECTO73_00699 ENOG4105NF4 modulator of drug activity ECTO73_00700 ENOG4105DHQ Histidine kinase ECTO73_00701 ENOG4105XJC Two component transcriptional regulator (Winged helix family ECTO73_00702 ENOG4105H4F exported protein ECTO73_00703 ENOG4105F4I Transcriptional regulator ECTO73_00704 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation ECTO73_00705 ENOG4105WJ3 XRE family Transcriptional regulator ECTO73_00706 ENOG4108J59 Extracellular solute-binding protein, family 5 ECTO73_00707 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ECTO73_00708 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase ECTO73_00709 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) ECTO73_00710 ENOG4105CCT upf0313 protein ECTO73_00712 ENOG4105ZKC Conserved Protein ECTO73_00713 ENOG4105CV8 reductase ECTO73_00714 ENOG4108I6A alcohol dehydrogenase ECTO73_00715 ENOG4105CF7 AraC family transcriptional regulator ECTO73_00716 ENOG4108K81 inner membrane protein YghB ECTO73_00717 ENOG4105C28 cystathionine ECTO73_00718 ENOG4105CWK Biopolymer transport protein, ExbB ECTO73_00719 ENOG4108ZZF transport protein (ExbD) ECTO73_00720 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ECTO73_00722 ENOG4105CPC Aldo Keto reductase ECTO73_00726 ENOG410900S Protein of unknown function (DUF2623) ECTO73_00727 ENOG4105E3S small subunit ECTO73_00728 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ECTO73_00729 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit ECTO73_00730 ENOG4105DPX Hydrogenase, large subunit ECTO73_00731 ENOG4108USZ hydrogenase ECTO73_00732 ENOG4108WGS hydrogenase 2-specific chaperone ECTO73_00733 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) ECTO73_00734 ENOG41082MF Hydrogenase assembly chaperone hypC hupF ECTO73_00735 ENOG4105CYM Glutathione S-transferase ECTO73_00736 ENOG4106032 Glutathionylspermidine synthase ECTO73_00737 ENOG4105CJ3 phosphate transporter ECTO73_00738 ENOG4108GH0 ATP-binding protein yghT ECTO73_00739 ENOG4108NDC ATP-binding protein yghS ECTO73_00740 ENOG4106FPV ATP-binding protein YghR ECTO73_00741 ENOG4108S55 polysaccharide biosynthesis protein ECTO73_00744 ENOG4108UUE Transcriptional regulator ECTO73_00745 ENOG4108M8S permease YjgP YjgQ family protein ECTO73_00747 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ECTO73_00748 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) ECTO73_00750 ENOG4107RCI amp-dependent synthetase and ligase ECTO73_00752 ENOG4108KWP DNA-binding transcriptional regulator GlcC ECTO73_00753 ENOG4105CQB FAD linked oxidase domain protein ECTO73_00754 ENOG4105EU8 FAD linked oxidase domain protein ECTO73_00755 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ECTO73_00756 ENOG4108ZJF Glcg protein ECTO73_00757 ENOG4107QP3 malate synthase g ECTO73_00759 ENOG4105DAA L-lactate ECTO73_00760 ENOG4105F88 accessory colonization factor AcfD ECTO73_00761 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) ECTO73_00763 ENOG410765S (LipO)protein ECTO73_00764 ENOG4108XKW General secretion pathway protein C ECTO73_00766 ENOG4107QHF type ii secretion system protein e ECTO73_00767 ENOG4107QHF type ii secretion system protein e ECTO73_00768 ENOG4105D7Q type ii secretion system ECTO73_00769 ENOG4108VAU general secretion pathway protein G ECTO73_00771 ENOG4105X5Z General secretion pathway protein I ECTO73_00775 ENOG4105U1E general secretion pathway protein M ECTO73_00777 ENOG4108UQV Membrane ECTO73_00778 ENOG4105CXN decarboxylase ECTO73_00779 ENOG4105EAA nucleoside ECTO73_00782 ENOG4105CEN a g-specific adenine glycosylase ECTO73_00784 ENOG41090ED Protein with unknown function (DUF469) ECTO73_00785 ENOG4105K33 Periplasmic Protein ECTO73_00786 ENOG4105HDK L-asparaginase ECTO73_00787 ENOG4106MH3 alpha helix chain ECTO73_00788 ENOG4105CSA Coproporphyrinogen iii oxidase ECTO73_00789 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) ECTO73_00791 ENOG4108VIA integral membrane protein ECTO73_00792 ENOG4105DFA alanine racemase domain protein ECTO73_00793 ENOG4105CZX twitching motility protein ECTO73_00796 ENOG4105D7Z glutathione synthase ECTO73_00797 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ECTO73_00798 ENOG4105RWS endonuclease I ECTO73_00800 ENOG4107QNK )-transporter ECTO73_00803 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) ECTO73_00805 ENOG4108K0D peptidase, M48 ECTO73_00806 ENOG4105CV1 Transketolase (EC 2.2.1.1) ECTO73_00807 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia ECTO73_00808 ENOG4105CTS PTS system mannitol-specific ECTO73_00809 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein ECTO73_00810 ENOG4108Q8A Fructose-1,6-bisphosphatase ECTO73_00811 ENOG4108R4K DNA-binding, transcriptional regulator ECTO73_00812 ENOG4107Z1W Fructose transport system kinase ECTO73_00815 ENOG4105D2N Aldolase ECTO73_00816 ENOG4105D64 Mechanosensitive ion channel ECTO73_00817 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ECTO73_00818 ENOG4105MPN Membrane ECTO73_00819 ENOG4105DEQ transcriptional regulator ECTO73_00820 ENOG4105CYC Transferase ECTO73_00821 ENOG4108M7F enoyl-CoA hydratase isomerase ECTO73_00822 ENOG4105DJT lAO AO transport system ATPase ECTO73_00823 ENOG4105D5P Methylmalonyl-coA mutase ECTO73_00827 ENOG4108JQ1 Dehydrogenase ECTO73_00829 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ECTO73_00833 ENOG4107RAQ aminopeptidase ECTO73_00834 ENOG4105D0A hydroxylase ECTO73_00835 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ECTO73_00839 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ECTO73_00840 ENOG4105CS2 ec 3.2.1.21 ECTO73_00841 ENOG4105N5Z UPF0267 protein ECTO73_00842 ENOG4108UT2 hemolysin iii ECTO73_00844 ENOG4105Y75 tpr repeat protein ECTO73_00845 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB ECTO73_00846 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) ECTO73_00847 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ECTO73_00848 ENOG4105T95 Thiol disulfide interChange protein ECTO73_00849 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ECTO73_00851 ENOG4105CRK lysyL-tRNA synthetase ECTO73_00854 ENOG4105C2W permease ECTO73_00855 ENOG4105BZ8 glutamate synthase ECTO73_00856 ENOG4108R8B oxidoreductase Fe-S subunit ECTO73_00857 ENOG4105C7N Xanthine uracil vitamin C permease ECTO73_00858 ENOG4107QUY Guanine deaminase ECTO73_00859 ENOG4105C2W permease ECTO73_00860 ENOG4105C7W Xanthine dehydrogenase ECTO73_00861 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase ECTO73_00862 ENOG4107UUR Chlorohydrolase aminohydrolase ECTO73_00863 ENOG4105BZ8 glutamate synthase ECTO73_00864 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase ECTO73_00865 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC ECTO73_00866 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family ECTO73_00867 ENOG4105C5B carbamate kinase ECTO73_00869 ENOG4107S4Y M20 DapE family protein YgeY ECTO73_00870 ENOG4107RCH Diaminopropionate ammonia-lyase ECTO73_00871 ENOG4105IW6 Carbamoyltransferase ECTO73_00872 ENOG4108JUB Transcriptional regulator ECTO73_00873 ENOG4108UTP (2Fe-2S)-binding domain protein ECTO73_00874 ENOG4108HR6 Dehydrogenase ECTO73_00875 ENOG4105C7W Xanthine dehydrogenase ECTO73_00876 ENOG4108K5P (LipO)protein ECTO73_00878 ENOG4108T88 ECTO73_00880 ENOG4108SER Transposase ECTO73_00883 ENOG41075IY surface presentation of antigens protein SpaP ECTO73_00885 ENOG4108TN6 type iii secretion ECTO73_00886 ENOG4108M6W surface presentation of antigens protein SpaS ECTO73_00887 ENOG4108M6W surface presentation of antigens protein SpaS ECTO73_00890 ENOG4108RC9 Type III secretion system protein ECTO73_00891 ENOG4108RC9 Type III secretion system protein ECTO73_00892 ENOG4105Y7Q type iii secretion ECTO73_00893 ENOG4106BTR ECTO73_00894 ENOG4108RBT type iii secretion ECTO73_00901 ENOG4108YAB Invasion protein ECTO73_00906 ENOG4105FV3 ECTO73_00907 ENOG4108TC1 Transcriptional regulator ECTO73_00909 ENOG4105ISV protein with bipartite regulator domain ECTO73_00910 ENOG4108MHD transport protein ECTO73_00911 ENOG4105CHU acetyl-coa acetyltransferase ECTO73_00913 ENOG4105CHR reductase ECTO73_00914 ENOG4107QNK )-transporter ECTO73_00916 ENOG4105RQF LysR family Transcriptional regulator ECTO73_00917 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ECTO73_00918 ENOG41060NJ transcriptional regulator ECTO73_00923 ENOG4105CPC Aldo Keto reductase ECTO73_00924 ENOG4105SUV lipoprotein YgdR ECTO73_00925 ENOG4105EE5 Membrane protein terC ECTO73_00929 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase ECTO73_00932 ENOG4105IPU prepilin peptidase dependent protein A ECTO73_00933 ENOG4105JCS prepilin peptidase dependent protein ECTO73_00934 ENOG4105SEN Protein of unknown function (DUF2509) ECTO73_00935 ENOG4105RVB Prepilin peptidase dependent protein c ECTO73_00936 ENOG4105DSY exodeoxyribonuclease V, gamma ECTO73_00937 ENOG4107QXK peptidase ECTO73_00938 ENOG4107QKA exodeoxyribonuclease V beta ECTO73_00939 ENOG4107QYX exodeoxyribonuclease v alpha ECTO73_00940 ENOG4107QZM n-acetylglutamate synthase ECTO73_00941 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ECTO73_00945 ENOG4105CA3 membrane-bound lytic murein transglycosylase ECTO73_00946 ENOG4105CUZ uba thif-type nad fad binding protein ECTO73_00947 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) ECTO73_00948 ENOG4105C9B Cysteine desulfurase ECTO73_00949 ENOG4105M5B (LipO)protein ECTO73_00951 ENOG4105ETT transcriptional Regulator, LysR family ECTO73_00952 ENOG4105M08 Membrane ECTO73_00954 ENOG4107EDW L-fucose operon activator ECTO73_00956 ENOG4105CMG Carbohydrate kinase ECTO73_00958 ENOG4105EDR glucose galactose transporter ECTO73_00959 ENOG4107W7X Aldolase ECTO73_00960 ENOG4105C0A alcohol dehydrogenase ECTO73_00962 ENOG4105EJQ L-serine dehydratase ECTO73_00963 ENOG4105C44 Serine transporter ECTO73_00964 ENOG4105EWT decarboxylase family ECTO73_00968 ENOG4105WP7 tRNA pseudouridine synthase C ECTO73_00969 ENOG4105DR9 pseudouridine synthase ECTO73_00970 ENOG4105QDK Flavodoxin ECTO73_00971 ENOG4105DJB Major Facilitator Superfamily ECTO73_00972 ENOG4105EQX glucarate dehydratase ECTO73_00973 ENOG4105EQX glucarate dehydratase ECTO73_00974 ENOG4105BZU Histidine kinase ECTO73_00975 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ECTO73_00976 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ECTO73_00977 ENOG4106A2Z transcriptional regulator antitoxin, MazE ECTO73_00978 ENOG4105MZG transcriptional modulator of maze toxin, mazf ECTO73_00979 ENOG4105DXN mazG family ECTO73_00982 ENOG4105HA9 of methanol dehydrogenase type ECTO73_00984 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ECTO73_00985 ENOG4108CWB sugar kinase ygcE ECTO73_00986 ENOG4108ITV Inner membrane protein yqcE ECTO73_00987 ENOG4105CHR reductase ECTO73_00988 ENOG4107R3A FAD linked oxidase domain protein ECTO73_00989 ENOG4105C54 Major Facilitator superfamily ECTO73_00990 ENOG4106IKH Electron transfer flavoprotein ECTO73_00991 ENOG4105YBM electron transfer flavoprotein subunit ygcQ ECTO73_00992 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator ECTO73_00993 ENOG4105WQV ferredoxin-like protein ECTO73_00994 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase ECTO73_00995 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase ECTO73_01000 ENOG4105DTT CRISPR-associated helicase, cas3 ECTO73_01001 ENOG4105CYR Crispr-associated protein, cse1 family ECTO73_01002 ENOG41061HK CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) ECTO73_01003 ENOG41060M0 Crispr-associated protein, cse4 family ECTO73_01004 ENOG4108VWQ crispr-associated protein ECTO73_01005 ENOG4108Y7V CRISPR-associated protein, Cse3 family ECTO73_01006 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) ECTO73_01007 ENOG4105PWE CRISPR-associated protein cas2 ECTO73_01008 ENOG4108MXK alkaline phosphatase isozyme conversion ECTO73_01012 ENOG4105N0Z inner membrane protein ygbE ECTO73_01019 ENOG4108K5P (LipO)protein ECTO73_01020 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ECTO73_01021 ENOG4105C6Z Gluconate ECTO73_01022 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) ECTO73_01023 ENOG4105FB2 class II Aldolase ECTO73_01024 ENOG4105G63 Type III effector Hrp-dependent ECTO73_01025 ENOG4105ZXK Dehydrogenase ECTO73_01026 ENOG4105MVE transcriptional regulator ECTO73_01027 ENOG4105MEW serine threonine protein phosphatase ECTO73_01030 ENOG4105VXR cytoplasmic protein ECTO73_01031 ENOG4108JUA Transcriptional regulator ECTO73_01032 ENOG4105C45 hydrogenase expression formation protein (HypE) ECTO73_01033 ENOG4105CQS hydrogenase expression formation protein HypD ECTO73_01034 ENOG41083WG hydrogenase assembly chaperone ECTO73_01035 ENOG4107RSS Hydrogenase accessory protein HypB ECTO73_01036 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) ECTO73_01037 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA ECTO73_01038 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) ECTO73_01039 ENOG4107R30 NADH dehydrogenase ECTO73_01040 ENOG4107TDF Formate hydrogenlyase subunit 4 ECTO73_01041 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ECTO73_01042 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit ECTO73_01043 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit ECTO73_01044 ENOG4105I6X formate hydrogenlyase maturation ECTO73_01045 ENOG4108MG9 hydrogenase 3 maturation protease ECTO73_01046 ENOG4105CS2 ec 3.2.1.21 ECTO73_01047 ENOG4105C5Y PTS System ECTO73_01048 ENOG4105DDV Transcriptional regulator (LacI family ECTO73_01049 ENOG4108RC0 Electron transport protein ECTO73_01050 ENOG4105C8H hydrogenase maturation protein Hypf ECTO73_01052 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center ECTO73_01054 ENOG4105C2X Arabinose 5-phosphate isomerase ECTO73_01055 ENOG410804X Transcriptional regulator ECTO73_01056 ENOG4105J92 DNA-binding transcriptional activator GutM ECTO73_01057 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase ECTO73_01058 ENOG4105VI0 Pts system, glucitol sorbitol-specific ECTO73_01059 ENOG4105DZY Pts system, glucitol sorbitol-specific ECTO73_01060 ENOG410787A Pts system, glucitol sorbitol-specific ECTO73_01061 ENOG4105CVE Lytic murein transglycosylase ECTO73_01062 ENOG4107TH8 cina domain protein ECTO73_01065 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) ECTO73_01066 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) ECTO73_01073 ENOG4107VXZ Hydrolase ECTO73_01074 ENOG4105W39 Membrane ECTO73_01078 ENOG4105C0R drug resistance transporter emrb qaca subfamily ECTO73_01079 ENOG4105CW7 secretion protein, HlyD family ECTO73_01080 ENOG4105NTK Transcriptional repressor Mpra ECTO73_01081 ENOG4105ZED uncharacterized protein ygaH ECTO73_01082 ENOG4108UMN azlc family ECTO73_01084 ENOG4105GIJ Glycine betaine ECTO73_01085 ENOG4108HQS Glycine betaine ECTO73_01086 ENOG4108IJ7 Glycine betaine ECTO73_01087 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ECTO73_01088 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ECTO73_01089 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) ECTO73_01090 ENOG4105WAZ (Glutaredoxin-like protein) NrdH ECTO73_01091 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) ECTO73_01092 ENOG4108WMJ Protein of unknown function (DUF2002) ECTO73_01093 ENOG4108RNS Exports L-alanine (By similarity) ECTO73_01094 ENOG4108X73 DNA- binding protein ECTO73_01095 ENOG4108V62 Rhodanese domain protein ECTO73_01096 ENOG41080HT Transcriptional regulator, arsr family ECTO73_01097 ENOG4105VPI YqaE family transport protein ECTO73_01098 ENOG4109066 lysm domain bon superfamily protein ECTO73_01099 ENOG4108PVQ transcriptional regulator ECTO73_01100 ENOG4105C85 amino acid ECTO73_01101 ENOG4108JPW Aminotransferase ECTO73_01102 ENOG4105C26 Dehydrogenase ECTO73_01103 ENOG4105D5U fad dependent oxidoreductase ECTO73_01105 ENOG4105E54 alpha-amylase ECTO73_01106 ENOG4105E54 alpha-amylase ECTO73_01107 ENOG4105E54 alpha-amylase ECTO73_01111 ENOG4108MGN ATP-binding component of a transport system ECTO73_01133 ENOG4105DFP Integrase ECTO73_01137 ENOG4108Z1B Cyclase dehydrase ECTO73_01138 ENOG4105VDB UPF0125 protein ECTO73_01139 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ECTO73_01140 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ECTO73_01143 ENOG4108JU6 CBS domain protein ECTO73_01144 ENOG4106KVJ cytochrome C assembly protein ECTO73_01145 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ECTO73_01150 ENOG41090EK ompa motb domain protein ECTO73_01151 ENOG4108KHX Diguanylate cyclase ECTO73_01152 ENOG4108WS1 ECTO73_01153 ENOG4105QP9 Protein of unknown function (DUF2799) ECTO73_01154 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ECTO73_01155 ENOG4105EHE chorismate mutase- prephenate dehydrogenase ECTO73_01156 ENOG4105CQC Prephenate dehydratase ECTO73_01158 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA ECTO73_01159 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ECTO73_01160 ENOG4105C34 Pseudouridine synthase ECTO73_01161 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ECTO73_01162 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ECTO73_01168 ENOG4105CSH Transporter ECTO73_01169 ENOG4105T42 (LipO)protein ECTO73_01170 ENOG4105JIM Phosphatidylserine synthase ECTO73_01171 ENOG4105CD5 CoA-binding domain protein ECTO73_01172 ENOG4106IUH DTW domain containing protein ECTO73_01173 ENOG4105K63 Thioredoxin ECTO73_01174 ENOG4105EIB trna rrna methyltransferase ECTO73_01178 ENOG41090KR LysR family transcriptional Regulator ECTO73_01179 ENOG4105C1J atp-dependent rna helicase ECTO73_01180 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) ECTO73_01181 ENOG4108IYU L-aspartate oxidase ECTO73_01182 ENOG4105EMN RNA polymerase sigma factor ECTO73_01183 ENOG41069PW sigma-e factor negative regulatory protein ECTO73_01184 ENOG4105VQK sigma E regulatory protein, MucB RseB ECTO73_01185 ENOG4105WMJ Positive regulator of sigma E, RseC MucC ECTO73_01187 ENOG4105C3F Signal peptidase i ECTO73_01192 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) ECTO73_01194 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ECTO73_01195 ENOG4106G6Q Transcriptional regulator ECTO73_01196 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB ECTO73_01197 ENOG4108Z6B deaminase ECTO73_01199 ENOG4107QIK phosphoribosylformylglycinamidine synthase ECTO73_01202 ENOG4107WP9 Histidine kinase ECTO73_01203 ENOG4108SKK alpha helix protein ECTO73_01204 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ECTO73_01205 ENOG4108YZA Nitrogen regulatory protein pii ECTO73_01206 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ECTO73_01208 ENOG4108NZE NAGC-like transcriptional regulator ECTO73_01209 ENOG4107HQ7 repeat protein ECTO73_01210 ENOG4105FCA ABC transporter periplasmic-binding protein YphF ECTO73_01211 ENOG4108F37 ATP-binding component of a transport system ECTO73_01212 ENOG4105CNN ABC, transporter ECTO73_01213 ENOG4105CPQ Dehydrogenase ECTO73_01214 ENOG4108ZKT aldose 1-epimerase ECTO73_01215 ENOG4108SB3 DoxX Family ECTO73_01220 ENOG4105FUY alpha subunit ECTO73_01221 ENOG4108W5M transcriptional regulator ECTO73_01222 ENOG4105D8G Major Facilitator superfamily ECTO73_01223 ENOG4108MN2 Stationary phase inducible protein CsiE ECTO73_01224 ENOG4107XM9 (LipO)protein ECTO73_01230 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins ECTO73_01234 ENOG4108ZIT Ferredoxin, 2FE-2S ECTO73_01235 ENOG4105WVQ Fe-S assembly protein IscX ECTO73_01237 ENOG4105YYA enhanced serine sensitivity protein SseB ECTO73_01240 ENOG4105KHC sulfurtransferase ECTO73_01241 ENOG4105DN3 alpha-2-macroglobulin domain protein ECTO73_01242 ENOG4108JQB penicillin-binding protein 1C ECTO73_01249 ENOG4105N21 Membrane ECTO73_01252 ENOG4105VPD cellular component movement ECTO73_01254 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ECTO73_01256 ENOG41066DY Membrane ECTO73_01257 ENOG4108ZMA Outer membrane lipoprotein ECTO73_01258 ENOG41062G3 Protein of unknown function (DUF2633) ECTO73_01260 ENOG4105BZU Histidine kinase ECTO73_01261 ENOG4105C9X ppx gppa phosphatase ECTO73_01262 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) ECTO73_01263 ENOG4108V3E phosphoribosylglycinamide formyltransferase ECTO73_01266 ENOG4105C2W permease ECTO73_01268 ENOG4105K89 arsenate reductase ECTO73_01269 ENOG4105ERG peptidase m48, ste24p ECTO73_01270 ENOG4105C02 permease ECTO73_01271 ENOG4105TMB Formate nitrite transporter ECTO73_01272 ENOG4108JUA Transcriptional regulator ECTO73_01273 ENOG4105I6X formate hydrogenlyase maturation ECTO73_01274 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit ECTO73_01276 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ECTO73_01277 ENOG4108JPZ Monovalent cation H antiporter subunit D ECTO73_01278 ENOG4107WQX hydrogenase 4 membrane subunit ECTO73_01279 ENOG4105D65 subunit l ECTO73_01280 ENOG4107TDF Formate hydrogenlyase subunit 4 ECTO73_01281 ENOG4108JPZ Monovalent cation H antiporter subunit D ECTO73_01282 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) ECTO73_01283 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ECTO73_01284 ENOG4105RH4 Glycine cleavage system transcriptional repressor ECTO73_01286 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ECTO73_01289 ENOG4105CGZ zinc metallopeptidase ECTO73_01290 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) ECTO73_01291 ENOG4106KED esterase YpfH ECTO73_01294 ENOG4105KUZ arsenate reductase ECTO73_01295 ENOG4105BZS acriflavin resistance protein ECTO73_01296 ENOG4105BZU Histidine kinase ECTO73_01297 ENOG4105BZ8 glutamate synthase ECTO73_01298 ENOG4107VIJ nudix hydrolase ECTO73_01299 ENOG4108PVD exported protein ECTO73_01300 ENOG4105CV1 Transketolase (EC 2.2.1.1) ECTO73_01301 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ECTO73_01302 ENOG4105C6K Malic enzyme ECTO73_01303 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place ECTO73_01304 ENOG4106S4J ethanolamine utilization protein EutP ECTO73_01305 ENOG4105NDK ethanolamine utilization protein ECTO73_01306 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase ECTO73_01307 ENOG4107WUY phosphate acetyltransferase ECTO73_01308 ENOG4105KNY Microcompartments protein ECTO73_01309 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml ECTO73_01310 ENOG4108EKI Dehydrogenase ECTO73_01311 ENOG4107RWI ethanolamine utilization protein eutJ ECTO73_01312 ENOG4105C0A alcohol dehydrogenase ECTO73_01313 ENOG4105ENY Ethanolamine utilization protein eutH ECTO73_01314 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase ECTO73_01315 ENOG4105CPD ethanolamine ammonia-lyase ECTO73_01317 ENOG4106D67 ethanolamine utilization protein ECTO73_01318 ENOG4108X49 Ethanolamine utilization protein EutK ECTO73_01319 ENOG4108K3Z AraC family transcriptional regulator ECTO73_01321 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase ECTO73_01322 ENOG4108R6G acetyltransferase ECTO73_01323 ENOG4105QZU Inner membrane protein YfeZ ECTO73_01324 ENOG4105E7K (LipO)protein ECTO73_01325 ENOG4105EZR dyp-type peroxidase family protein ECTO73_01326 ENOG4107S1E Beta-lactamase ECTO73_01327 ENOG4105C5Y PTS System ECTO73_01330 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr ECTO73_01331 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein ECTO73_01332 ENOG4108I5D sulfate abc transporter ECTO73_01333 ENOG4105ECW sulfate abc transporter ECTO73_01334 ENOG4108IJ6 ABC transporter ECTO73_01335 ENOG4105C6T cysteine synthase ECTO73_01336 ENOG4105WEC Molybdate metabolism regulator ECTO73_01337 ENOG4105M0Y ECTO73_01339 ENOG4105C5Y PTS System ECTO73_01340 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ECTO73_01341 ENOG4105KZ7 phosphocarrier protein hpr ECTO73_01342 ENOG4105C6T cysteine synthase ECTO73_01345 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) ECTO73_01346 ENOG4105VRT cytoplasmic protein ECTO73_01347 ENOG4105DHU Bile acid ECTO73_01348 ENOG4108M0I Transcriptional regulator ECTO73_01349 ENOG4108NFH Sugar hydrolase ECTO73_01350 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) ECTO73_01351 ENOG4105EAA nucleoside ECTO73_01352 ENOG4105CN8 Transcriptional regulator ECTO73_01358 ENOG4105GXM Putative transcription regulator (DUF1323) ECTO73_01359 ENOG4105HZG regulatoR ECTO73_01362 ENOG4108KMM Diguanylate cyclase ECTO73_01363 ENOG4105D9N nucleoside ECTO73_01365 ENOG4109076 Conserved Protein ECTO73_01366 ENOG4105VCT ion-transport protein YfeO ECTO73_01368 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) ECTO73_01369 ENOG410863U PTS System ECTO73_01370 ENOG4105DC7 peptidase M24 ECTO73_01371 ENOG4105CN9 Peptidase m42 family protein ECTO73_01372 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ECTO73_01373 ENOG4108CIP transcriptional regulator ECTO73_01374 ENOG4108CIP transcriptional regulator ECTO73_01375 ENOG4105DY9 regulatoR ECTO73_01376 ENOG4108HRK Histidine kinase ECTO73_01377 ENOG4105CHM Aminotransferase ECTO73_01378 ENOG4105D1S lipid A biosynthesis ECTO73_01379 ENOG4105W9M Membrane ECTO73_01381 ENOG4108V08 YfdX protein ECTO73_01383 ENOG4105CFN oxalyl-CoA decarboxylase ECTO73_01384 ENOG4108N2Y auxin Efflux ECTO73_01385 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F ECTO73_01386 ENOG4105BZU Histidine kinase ECTO73_01387 ENOG4108WQH regulatoR ECTO73_01388 ENOG4105CW7 secretion protein, HlyD family ECTO73_01389 ENOG4105C0R drug resistance transporter emrb qaca subfamily ECTO73_01391 ENOG4105C6Z Gluconate ECTO73_01392 ENOG4105W8I Transcriptional regulator ECTO73_01394 ENOG4105S64 Formate nitrite transporter ECTO73_01395 ENOG410903C (LipO)protein ECTO73_01397 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation ECTO73_01398 ENOG4105KZW UPF0381 protein ECTO73_01401 ENOG4108BY2 phosphohistidine phosphatase ECTO73_01403 ENOG4106PG1 outer membrane usher protein ECTO73_01404 ENOG4108FZ9 Chaperone ECTO73_01405 ENOG4105NEV Fimbrial ECTO73_01406 ENOG4105UGQ Fimbrial ECTO73_01407 ENOG4105US4 fimbrial-like protein yfcP ECTO73_01410 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) ECTO73_01413 ENOG4105EJ9 Membrane ECTO73_01414 ENOG4108BPE -transporting atpase ECTO73_01415 ENOG4105MH2 YfcL protein ECTO73_01416 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) ECTO73_01417 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ECTO73_01418 ENOG4105F9N Major Facilitator Superfamily ECTO73_01419 ENOG4106WZ1 flagella biosynthesis regulator ECTO73_01420 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) ECTO73_01421 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ECTO73_01423 ENOG4105DQR SNARE associated Golgi ECTO73_01425 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ECTO73_01426 ENOG4108S3P Sporulation domain protein ECTO73_01427 ENOG4105E96 Colicin v production protein ECTO73_01428 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase ECTO73_01429 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ECTO73_01430 ENOG4105E89 ABC transporter ECTO73_01431 ENOG4105E89 ABC transporter ECTO73_01432 ENOG4105DSP amino acid AbC transporter ECTO73_01433 ENOG4106YG3 ABC transporter ECTO73_01434 ENOG4108JEH abc transporter atp-binding protein ECTO73_01435 ENOG4105DNE Transposase ECTO73_01436 ENOG4105ECP epimerase ECTO73_01437 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase ECTO73_01438 ENOG4105CYM Glutathione S-transferase ECTO73_01439 ENOG4108SHQ Glutathione S-transferase ECTO73_01440 ENOG4108RE9 Phosphodiesterase ECTO73_01441 ENOG4105PTV Nudix Hydrolase ECTO73_01442 ENOG4105CSX c4-dicarboxylate anaerobic carrier ECTO73_01443 ENOG4105C6K Malic enzyme ECTO73_01444 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ECTO73_01447 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 ECTO73_01448 ENOG4107QWE )-transporter ECTO73_01450 ENOG4105CHM Aminotransferase ECTO73_01451 ENOG4107NQ8 LysR family Transcriptional regulator ECTO73_01455 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ECTO73_01456 ENOG4105GKE subunit e ECTO73_01457 ENOG4107QIZ NADH dehydrogenase ECTO73_01458 ENOG4107R0R NADH dehydrogenase subunit g ECTO73_01460 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ECTO73_01461 ENOG4107UFS subunit j ECTO73_01462 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ECTO73_01463 ENOG4105D65 subunit l ECTO73_01464 ENOG4105C8S subunit m ECTO73_01466 ENOG4106HDC ECTO73_01467 ENOG4106EES ECTO73_01468 ENOG4105ZD8 ECTO73_01469 ENOG4105GDX Domain of unknown function (DUF1877) ECTO73_01470 ENOG4107VAM peptidase, m28 ECTO73_01471 ENOG4105CP2 von willebrand factor, type a ECTO73_01472 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is ECTO73_01474 ENOG4107YB6 acetyltransferase, (GNAT) family ECTO73_01475 ENOG4105TNS Conserved Protein ECTO73_01476 ENOG4105E4F Isochorismate synthase ECTO73_01479 ENOG4108IPT Naphthoate synthase ECTO73_01481 ENOG4105CEY Amp-dependent synthetase and ligase ECTO73_01482 ENOG4106GZG polymyxin resistance protein B ECTO73_01483 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) ECTO73_01485 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) ECTO73_01486 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) ECTO73_01489 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ECTO73_01492 ENOG4108UII YfaZ family ECTO73_01494 ENOG4107258 Transcriptional regulator ECTO73_01495 ENOG4107258 Transcriptional regulator ECTO73_01497 ENOG4105CSP Major Facilitator Superfamily ECTO73_01500 ENOG4105DNE Transposase ECTO73_01501 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ECTO73_01503 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A ECTO73_01504 ENOG4105CXY transporter ECTO73_01505 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase ECTO73_01506 ENOG4107R11 Transcriptional regulator ECTO73_01507 ENOG4105FQR PH-inducible protein involved in stress response ECTO73_01508 ENOG4105XPH Ferredoxin ECTO73_01509 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ECTO73_01510 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ECTO73_01511 ENOG4107GHC outer membrane autotransporter ECTO73_01513 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ECTO73_01514 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) ECTO73_01515 ENOG4108QJJ Protein of unknown function (DUF1175) ECTO73_01516 ENOG4107S52 alpha-2-macroglobulin domain protein ECTO73_01517 ENOG41081SK signal peptide protein ECTO73_01518 ENOG4105EDV vault protein ECTO73_01519 ENOG4105CHU acetyl-coa acetyltransferase ECTO73_01520 ENOG4105CRW Short chain fatty acid transporter ECTO73_01521 ENOG4107QNJ CoA-transferase subunit B ECTO73_01522 ENOG4107QP7 CoA-transferase subunit A ECTO73_01523 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ECTO73_01524 ENOG4105BZU Histidine kinase ECTO73_01525 ENOG4105BZU Histidine kinase ECTO73_01526 ENOG41068CG regulatoR ECTO73_01527 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC ECTO73_01529 ENOG4105FCK Membrane ECTO73_01530 ENOG4105CJ2 (LipO)protein ECTO73_01531 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ECTO73_01532 ENOG4105CF1 Alkylated DNA repair protein ECTO73_01533 ENOG4105IBP Cyclic peptide transporter ECTO73_01537 ENOG4108ZNS ferredoxin-type protein NapF ECTO73_01538 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase ECTO73_01540 ENOG4108BGM Quinol dehydrogenase periplasmic component ECTO73_01541 ENOG4105GXZ Ferredoxin-type protein NapH ECTO73_01542 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) ECTO73_01543 ENOG4105CUW cytochrome C-TYPE protein ECTO73_01544 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) ECTO73_01545 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) ECTO73_01546 ENOG41060IM Heme exporter protein ECTO73_01547 ENOG4105X3C heme exporter protein ECTO73_01549 ENOG4105DA4 cytochrome c-type biogenesis protein ECTO73_01550 ENOG4107QX9 Thiol disulfide interChange protein ECTO73_01551 ENOG4105KWW Biogenesis protein ECTO73_01552 ENOG4105WH1 Two component transcriptional regulator luxr family ECTO73_01553 ENOG4108MGN ATP-binding component of a transport system ECTO73_01555 ENOG4105E68 Sulfatase ECTO73_01559 ENOG4105CFI type iii restriction protein res subunit ECTO73_01560 ENOG4105I08 Pseudouridine synthase ECTO73_01561 ENOG4105C2C drug resistance transporter, Bcr CflA ECTO73_01562 ENOG4105HG6 ECTO73_01563 ENOG4108JQ5 ABC transporter ECTO73_01564 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component ECTO73_01565 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component ECTO73_01566 ENOG4105E43 Extracellular solute-binding protein, family 5 ECTO73_01567 ENOG4105CXC rtn protein ECTO73_01568 ENOG4107TT5 NLP P60 protein ECTO73_01569 ENOG41076MN Phosphoesterase, PA-phosphatase related ECTO73_01570 ENOG4105CKI cobalamin synthesis protein ECTO73_01571 ENOG4105DEI Mannitol dehydrogenase ECTO73_01573 ENOG4105KRS Proteinase inhibitor ECTO73_01574 ENOG4105S8Q sugar efflux transporter ECTO73_01575 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein ECTO73_01576 ENOG4105DE4 1-phosphofructokinase ECTO73_01577 ENOG4105DM4 PTS System ECTO73_01578 ENOG4105DD7 kinase (PfkB family ECTO73_01579 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) ECTO73_01580 ENOG4105D9N nucleoside ECTO73_01581 ENOG4108Y4K DNA-binding transcriptional activator ECTO73_01583 ENOG4105D9N nucleoside ECTO73_01584 ENOG4105DD7 kinase (PfkB family ECTO73_01585 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) ECTO73_01586 ENOG4105HMI Membrane ECTO73_01587 ENOG4105DUM transcriptional regulator, lysR family ECTO73_01588 ENOG4108IQI permease ECTO73_01589 ENOG4105D05 Receptor ECTO73_01590 ENOG4105C4W S-formylglutathione hydrolase ECTO73_01592 ENOG4105DHF Membrane ECTO73_01593 ENOG41060NJ transcriptional regulator ECTO73_01594 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator ECTO73_01595 ENOG4105C2J ABC transporter ECTO73_01596 ENOG4108HWV )-transporter ECTO73_01597 ENOG4107SJI Dehydrogenase ECTO73_01598 ENOG4105BZ8 glutamate synthase ECTO73_01599 ENOG4105Y9N Membrane ECTO73_01600 ENOG4107GZ4 SanA protein ECTO73_01602 ENOG41067MG lrgb family ECTO73_01604 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) ECTO73_01605 ENOG4105ETP RND efflux system, outer membrane lipoprotein ECTO73_01606 ENOG4105H9W Short-chain dehydrogenase reductase Sdr ECTO73_01607 ENOG4105KHU inner membrane protein YohD ECTO73_01608 ENOG41069YE inner membrane protein yohC ECTO73_01609 ENOG41061WM D-Alanyl-D-Alanine ECTO73_01610 ENOG4105CXG d-lactate dehydrogenase ECTO73_01611 ENOG4107QK4 glycoside hydrolase, family 3 domain protein ECTO73_01612 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system ECTO73_01613 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component ECTO73_01614 ENOG4108IJ8 ABC transporter ECTO73_01615 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component ECTO73_01617 ENOG4108XDN Transcriptional regulator ECTO73_01618 ENOG4108HRK Histidine kinase ECTO73_01619 ENOG4108NEV two component transcriptional regulator, LytTR family ECTO73_01620 ENOG4108W15 Protein of unknown function (DUF1456) ECTO73_01621 ENOG4108YCW (LipO)protein ECTO73_01624 ENOG410903U zinc ion binding ECTO73_01625 ENOG4105DEG Vwa containing coxe family protein ECTO73_01626 ENOG4105RD5 ECTO73_01627 ENOG4105KKX ATPase associated with various cellular activities aaa_5 ECTO73_01630 ENOG4108KDT Molybdate metabolism regulator ECTO73_01631 ENOG4108KDT Molybdate metabolism regulator ECTO73_01632 ENOG4108KDT Molybdate metabolism regulator ECTO73_01634 ENOG4105D1F ATP-binding protein ECTO73_01635 ENOG41067AK Protein of unknown function (DUF2574) ECTO73_01636 ENOG41063W2 Fimbrial protein ECTO73_01637 ENOG4108MQF Chaperone ECTO73_01638 ENOG4105CW0 outer membrane usher protein ECTO73_01639 ENOG410662B Type-1 fimbrial protein ECTO73_01640 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly ECTO73_01645 ENOG4105DWF phosphomethylpyrimidine kinase ECTO73_01646 ENOG4108UQ1 hydrolase, family 25 ECTO73_01647 ENOG4105FDP GntR family transcriptional regulator ECTO73_01648 ENOG4108TFM Kinase, PfkB family ECTO73_01649 ENOG4108KD5 ADP-ribosylation crystallin J1 ECTO73_01650 ENOG4105EAA nucleoside ECTO73_01651 ENOG4105EIE fructose-bisphosphate aldolase ECTO73_01654 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of ECTO73_01657 ENOG4105DT3 PTS system, galactitol-specific IIc component ECTO73_01658 ENOG4107WTH Galactitol-1-phosphate dehydrogenase ECTO73_01661 ENOG4108ZQS transposase ECTO73_01662 ENOG4108MVM Transposase ECTO73_01663 ENOG41076Z6 Uncharacterized protein yegR ECTO73_01665 ENOG4105CFP Peptidase U32 ECTO73_01671 ENOG4105KWI UPF0339 protein ECTO73_01672 ENOG4105E3W Two component transcriptional regulator (Winged helix family ECTO73_01673 ENOG4105EB3 Histidine kinase ECTO73_01683 ENOG4108M24 von Willebrand factor, type A ECTO73_01684 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase ECTO73_01685 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding ECTO73_01686 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding ECTO73_01687 ENOG4105R8A Heat shock protein ECTO73_01688 ENOG4105D03 DNA-3-methyladenine glycosylase II ECTO73_01689 ENOG4105BZU Histidine kinase ECTO73_01690 ENOG4105DBI uridine monophosphokinase ECTO73_01692 ENOG4108GAE asmA family ECTO73_01695 ENOG4105EE5 Membrane protein terC ECTO73_01696 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ECTO73_01697 ENOG4105MH5 phosphoesterase PA-phosphatase related protein ECTO73_01698 ENOG4108ZSJ is1 orf2 ECTO73_01701 ENOG4108MRJ ECTO73_01702 ENOG4105DAY polysaccharide export protein ECTO73_01705 ENOG4105D3Q Sugar transferase ECTO73_01706 ENOG4108KBE Glycosyl transferase, family 2 ECTO73_01709 ENOG4108KBE Glycosyl transferase, family 2 ECTO73_01710 ENOG41090RK glycosyl transferase ECTO73_01711 ENOG4108RT7 Glycosyl transferase, family 2 ECTO73_01717 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) ECTO73_01718 ENOG4105C1B dTDP-glucose 4-6-dehydratase ECTO73_01720 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase ECTO73_01721 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase ECTO73_01723 ENOG4108ZSJ is1 orf2 ECTO73_01725 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase ECTO73_01728 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ECTO73_01729 ENOG4105ECC imidazole-glycerol-phosphate dehydratase ECTO73_01734 ENOG4105VTW prevent-host-death family ECTO73_01735 ENOG4105KRQ Addiction module toxin, Txe YoeB family ECTO73_01736 ENOG4108535 NAD dependent epimerase/dehydratase family ECTO73_01737 ENOG4105EQ1 Transcriptional regulator ECTO73_01739 ENOG4105CUB amino acid ECTO73_01740 ENOG4105CUC YeeE YedE family protein ECTO73_01742 ENOG4105CJB Exodeoxyribonuclease I ECTO73_01743 ENOG4105DZ1 carboxypeptidase ECTO73_01744 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) ECTO73_01745 ENOG4105DR8 Membrane ECTO73_01749 ENOG4105F5W AtP-binding protein ECTO73_01750 ENOG4105D70 Integrase catalytic subunit ECTO73_01753 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles ECTO73_01755 ENOG4106WJE Protein of unknown function (DUF987) ECTO73_01756 ENOG4108YGG dna repair protein ECTO73_01757 ENOG4105MFG Antirestriction protein ECTO73_01758 ENOG4106H6R UPF0380 protein ECTO73_01760 ENOG4105F4K antigen 43 ECTO73_01776 ENOG41080QX K07048 phosphotriesterase-related protein ECTO73_01778 ENOG4108ZSJ is1 orf2 ECTO73_01779 ENOG4108YZT Adenosylcobinamide kinase ECTO73_01782 ENOG4108PXI ErfK YbiS YcfS YnhG ECTO73_01784 ENOG4106P55 Transcriptional regulator ECTO73_01785 ENOG4107R11 Transcriptional regulator ECTO73_01787 ENOG4105UQX Mate efflux family protein ECTO73_01788 ENOG4105UQX Mate efflux family protein ECTO73_01790 ENOG4105CDY transcriptional regulatory protein ECTO73_01791 ENOG4105FYV Amp nucleosidase ECTO73_01792 ENOG4105CSH Transporter ECTO73_01798 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) ECTO73_01800 ENOG4108VKM cytochrome b561 ECTO73_01801 ENOG4108MEK Metal-binding protein YodA ECTO73_01803 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) ECTO73_01804 ENOG4105VT2 5-hydroxyisourate hydrolase ECTO73_01805 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ECTO73_01806 ENOG4107ZY3 Histidine kinase ECTO73_01808 ENOG4105ZIT Porin Gram-negative type ECTO73_01810 ENOG4105Y0K Inner membrane protein YedR ECTO73_01811 ENOG4105EST Metal Dependent Phosphohydrolase ECTO73_01812 ENOG4105DVF Cytosine-specific methyltransferase ECTO73_01813 ENOG41090BB DNA mismatch endonuclease (vsr) ECTO73_01814 ENOG4105FDR Membrane ECTO73_01815 ENOG4105CKW Inner membrane protein yedI ECTO73_01816 ENOG4105VNZ cytoplasmic protein ECTO73_01820 ENOG4105YX3 cellular response to acidity ECTO73_01822 ENOG4107TKS colanic acid capsular biosynthesis activation protein A ECTO73_01823 ENOG4105D19 Role in flagellar biosynthesis (By similarity) ECTO73_01824 ENOG4105VS8 Flagellar biosynthetic protein fliq ECTO73_01825 ENOG4105CN7 Flagellar biosynthetic protein FliP ECTO73_01826 ENOG4105K0P flagellar biosynthesis protein ECTO73_01827 ENOG4105DD5 Flagellar motor switch protein ECTO73_01828 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ECTO73_01829 ENOG4107ZI8 flagellar basal body-associated protein flil ECTO73_01830 ENOG4105WF4 Flagellar hook-length control protein ECTO73_01831 ENOG4105GSA Flagellar export protein flij ECTO73_01832 ENOG4108JIR Flagellum-specific ATP synthase ECTO73_01833 ENOG41090PJ Flagellar assembly protein ECTO73_01834 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ECTO73_01835 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) ECTO73_01837 ENOG410814C multidrug resistance protein ECTO73_01838 ENOG4108V1U phospholipid-binding protein ECTO73_01839 ENOG4108UQN AraC family transcriptional regulator ECTO73_01840 ENOG4108RS6 transposase ECTO73_01841 ENOG4105D7V transposase ECTO73_01842 ENOG4108RAV Conserved protein ECTO73_01843 ENOG4105KSU Redox protein ECTO73_01844 ENOG41066VF YeeE YedE family protein ECTO73_01845 ENOG4108W9D (LipO)protein ECTO73_01846 ENOG4105E5K Alpha-amylase ECTO73_01848 ENOG4105MQ3 flagellar protein FliS ECTO73_01849 ENOG4105DTS flagellar hook-associated ECTO73_01850 ENOG4105I03 Flagellin ECTO73_01851 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ECTO73_01852 ENOG4108M9K flagella biosynthesis protein FliZ ECTO73_01853 ENOG4105EAB amino acid AbC transporter ECTO73_01855 ENOG4105E5Q amino acid AbC transporter ECTO73_01856 ENOG4105CDA abc transporter atp-binding protein ECTO73_01857 ENOG4105VJY transcriptional regulator ECTO73_01858 ENOG4105XVG cytoplasmic protein ECTO73_01859 ENOG4105WH1 Two component transcriptional regulator luxr family ECTO73_01861 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ECTO73_01865 ENOG4106RHG Yeca family ECTO73_01866 ENOG4105E0U tyrosine-specific transport protein ECTO73_01867 ENOG4105VVZ metal-binding protein ECTO73_01868 ENOG41090A1 ferritin ECTO73_01869 ENOG4105P23 (LipO)protein ECTO73_01870 ENOG4105N4N Protein of unknown function (DUF2766) ECTO73_01871 ENOG4108UEC Ferritin-like protein ECTO73_01872 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator ECTO73_01873 ENOG4105C2J ABC transporter ECTO73_01874 ENOG4105CNN ABC, transporter ECTO73_01875 ENOG4108K4C ec 3.1.3.12 ECTO73_01877 ENOG4108VA4 Universal stress protein ECTO73_01879 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region ECTO73_01880 ENOG4107RD7 Flagellar Motor Protein, MotA ECTO73_01881 ENOG4105ER2 Ompa motb domain protein ECTO73_01882 ENOG4105CBS Chea signal transduction histidine kinase ECTO73_01883 ENOG4108V3W Chemotaxis protein, CheW ECTO73_01885 ENOG4105C8Q Methyl-accepting chemotaxis ECTO73_01886 ENOG4105C8Q Methyl-accepting chemotaxis ECTO73_01887 ENOG4105BZU Histidine kinase ECTO73_01888 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) ECTO73_01889 ENOG4108VYJ response regulator receiver protein ECTO73_01890 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) ECTO73_01891 ENOG4105D00 flagellar biosynthetic protein flhB ECTO73_01892 ENOG4105D7B Flagellar biosynthesis protein flha ECTO73_01893 ENOG4105W13 flagellar protein ECTO73_01896 ENOG4106ZCM YecM protein ECTO73_01898 ENOG4105CUW cytochrome C-TYPE protein ECTO73_01899 ENOG4107QY8 reductase ECTO73_01902 ENOG4105WJG Glutathione ECTO73_01903 ENOG41081XQ Conserved Protein ECTO73_01904 ENOG4105D3W isochorismatase ECTO73_01906 ENOG4108TIT dATP pyrophosphohydrolase ECTO73_01907 ENOG4105CDY transcriptional regulatory protein ECTO73_01909 ENOG4107S01 Repressor protein MetJ ECTO73_01912 ENOG4105FAV ABC, transporter ECTO73_01913 ENOG4105FDK ABC transporter ECTO73_01914 ENOG4105NXV High-affinity zinc uptake system protein ECTO73_01915 ENOG4105DR5 peptidase ECTO73_01916 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase ECTO73_01917 ENOG4105CA9 Pyruvate kinase ECTO73_01918 ENOG4106KNT transcriptional regulator ECTO73_01920 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ECTO73_01921 ENOG4105C01 Dihydroxy-acid dehydratase ECTO73_01922 ENOG4108UHU Aldolase ECTO73_01924 ENOG4105X2V dna damage-inducible protein ECTO73_01925 ENOG4105RSZ secreted protein ECTO73_01927 ENOG4108Q2J Inner membrane protein YebE ECTO73_01928 ENOG4105CUG Oligopeptidase b ECTO73_01929 ENOG4105UMD exodeoxyribonuclease X ECTO73_01930 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ECTO73_01931 ENOG4105MPK DNA polymerase III subunit theta ECTO73_01932 ENOG4105FXM Copper resistance protein ECTO73_01933 ENOG4108PNC copper resistance ECTO73_01934 ENOG4105NKT exported protein ECTO73_01937 ENOG4108R1E Serine threonine protein phosphatase 1 ECTO73_01938 ENOG4105UVW uncharacterized protein yebW ECTO73_01939 ENOG4105WT8 Protein of unknown function (DUF1480) ECTO73_01941 ENOG4105DY2 Paraquat-inducible protein b ECTO73_01942 ENOG4105H2K paraquat-inducible protein a ECTO73_01943 ENOG4108ZGC gaf domain protein ECTO73_01945 ENOG4105CN1 protease ECTO73_01947 ENOG4105C0R drug resistance transporter emrb qaca subfamily ECTO73_01948 ENOG4105J4Q Transcriptional regulator ECTO73_01949 ENOG4105TIK ECTO73_01950 ENOG4105Q3Y exported protein ECTO73_01952 ENOG4105VEQ Cold shock protein ECTO73_01953 ENOG4105DHI Methyltransferase ECTO73_01956 ENOG4105F3R pts system mannose fructose sorbose family iid ECTO73_01957 ENOG4105ETZ PTS System ECTO73_01958 ENOG4108EQA pts system ECTO73_01960 ENOG4105EE5 Membrane protein terC ECTO73_01961 ENOG4107XTP (EAL) domain protein ECTO73_01962 ENOG4105EJQ L-serine dehydratase ECTO73_01964 ENOG4105CRQ synthase (Component I) ECTO73_01966 ENOG4105V2F Uncharacterized protein yoac ECTO73_01967 ENOG4105M4H endoribonuclease L-psp ECTO73_01968 ENOG4105DVT helicase ECTO73_01969 ENOG41072GX Peptidase M22 Glycoprotease ECTO73_01970 ENOG4105Y4Z Outer Membrane Lipoprotein ECTO73_01971 ENOG4105CEY Amp-dependent synthetase and ligase ECTO73_01973 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) ECTO73_01974 ENOG4105E3J oxidoreductase ECTO73_01975 ENOG4105DVW rieske (2Fe-2S) ECTO73_01976 ENOG4105C94 Transporter ECTO73_01977 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ECTO73_01978 ENOG4105EJC lysr family transcriptional regulator ECTO73_01980 ENOG4108YS1 cytoplasmic protein ECTO73_01981 ENOG4105YP6 Domain of unknown function (DUF1869) ECTO73_01982 ENOG4105Y3U Transglycosylase-associated protein ECTO73_01983 ENOG410620I Diguanylate cyclase ECTO73_01984 ENOG4105UCG Domain of unknown function (DUF333) ECTO73_01985 ENOG4105K78 MarR family Transcriptional regulator ECTO73_01986 ENOG4105DJ2 Major Facilitator Superfamily ECTO73_01987 ENOG4105R1U AraC Family Transcriptional Regulator ECTO73_01989 ENOG4108KXH Ybak prolyl-tRNA synthetase associated ECTO73_01990 ENOG4108KHP Diguanylate cyclase ECTO73_01991 ENOG4106KTS Inner membrane protein yeaI ECTO73_01993 ENOG4105CYN Serine protein kinase ECTO73_01994 ENOG4105GNX MltA-interacting MipA family protein ECTO73_01995 ENOG4105CV8 reductase ECTO73_01996 ENOG4105DSB aldose 1-epimerase ECTO73_01997 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ECTO73_01999 ENOG4105VUT cytoplasmic protein ECTO73_02000 ENOG4105CPQ Dehydrogenase ECTO73_02001 ENOG4107TE1 transport protein ECTO73_02002 ENOG4105CPQ Dehydrogenase ECTO73_02004 ENOG4105D2N Aldolase ECTO73_02005 ENOG4107UH8 sugar kinase ECTO73_02006 ENOG4105CPC Aldo Keto reductase ECTO73_02007 ENOG4105E98 transcriptional regulator DeoR family ECTO73_02008 ENOG4108KUU Inner membrane metabolite transport protein ydjE ECTO73_02009 ENOG4108RWI nicotinamidase ECTO73_02010 ENOG4105HDK L-asparaginase ECTO73_02011 ENOG4105D07 Signal peptide peptidase, SppA ECTO73_02012 ENOG41069NU Nitroreductase ECTO73_02014 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ECTO73_02015 ENOG41065FB inner membrane protein ynji ECTO73_02016 ENOG4105D82 Glutamate dehydrogenase ECTO73_02017 ENOG4105MTM Protein of unknown function (DUF1496) ECTO73_02018 ENOG4105M6F mutator MutT protein ECTO73_02019 ENOG4108T9J Cdp-alcohol phosphatidyltransferase ECTO73_02020 ENOG4107RM6 sulfurtransferase ECTO73_02021 ENOG4108VGW abc transporter atp-binding protein ECTO73_02022 ENOG4105CXZ ABC transporter, permease ECTO73_02023 ENOG4105VNH ABC transporter solute-binding protein ECTO73_02024 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) ECTO73_02025 ENOG4108N5C SNARE associated Golgi protein-related protein ECTO73_02026 ENOG4108KCW iron-sulfur cluster binding ECTO73_02027 ENOG4108RSN SNARE associated Golgi ECTO73_02028 ENOG4105CGK Exodeoxyribonuclease III ECTO73_02030 ENOG4105F4X arginine ECTO73_02034 ENOG4108SPG Periplasmic Protein ECTO73_02036 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) ECTO73_02038 ENOG4105KKI DNA-binding transcriptional activator OsmE ECTO73_02039 ENOG4105VZJ PTS System ECTO73_02040 ENOG4105CK1 PTS System ECTO73_02041 ENOG4105VCP PTS System ECTO73_02042 ENOG4105EZV Transcriptional regulator ECTO73_02043 ENOG4105F8D glycoside hydrolase family 4 ECTO73_02045 ENOG4105CH6 catalase ECTO73_02048 ENOG4108ETY sodium dicarboxylate symporter ECTO73_02049 ENOG4107K5X Membrane-bound metal-dependent hydrolase ECTO73_02050 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 ECTO73_02051 ENOG4107PN8 YfeABCD locus regulator ECTO73_02052 ENOG4105FGM Fructosamine kinase ECTO73_02053 ENOG4105P10 Uncharacterized protein ydiZ ECTO73_02054 ENOG4105DE4 1-phosphofructokinase ECTO73_02055 ENOG4108NE3 Salt-induced outer membrane protein ECTO73_02061 ENOG41082NX 50s ribosomal protein l35 ECTO73_02062 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) ECTO73_02065 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ECTO73_02069 ENOG4108V06 Glutathione peroxidase ECTO73_02071 ENOG4108QBX (LipO)protein ECTO73_02072 ENOG4108TC0 Diguanylate phosphodiesterase ECTO73_02074 ENOG4106EDX Hemin uptake protein ECTO73_02075 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ECTO73_02077 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) ECTO73_02078 ENOG4105CEY Amp-dependent synthetase and ligase ECTO73_02079 ENOG41090P5 ferredoxin-like protein ECTO73_02080 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase ECTO73_02081 ENOG4105C10 Electron transfer flavoprotein ECTO73_02082 ENOG4105CV7 Electron transfer flavoprotein ECTO73_02083 ENOG4105W4W Transcriptional regulator ECTO73_02084 ENOG4105C1G acyl-Coa dehydrogenase ECTO73_02085 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) ECTO73_02088 ENOG4105EMV Major Facilitator ECTO73_02089 ENOG4105EMV Major Facilitator ECTO73_02090 ENOG4105SUA Ydil protein ECTO73_02092 ENOG4105IPI Membrane ECTO73_02093 ENOG4105CQB FAD linked oxidase domain protein ECTO73_02094 ENOG4105KA0 thioesterase Superfamily protein ECTO73_02095 ENOG410671Z uncharacterized protein ydiH ECTO73_02097 ENOG4108Z4V iron-sulfur cluster assembly ECTO73_02098 ENOG4105DIW FeS assembly protein SUFB ECTO73_02099 ENOG4105C3K feS assembly ATPase SufC ECTO73_02100 ENOG4105JRK feS assembly protein SufD ECTO73_02103 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ECTO73_02104 ENOG4105KMX major outer membrane lipoprotein ECTO73_02105 ENOG4105CA9 Pyruvate kinase ECTO73_02106 ENOG4105RFR Protein of unknown function (DUF2767) ECTO73_02107 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein ECTO73_02108 ENOG4105WE2 aldehyde ferredoxin oxidoreductase ECTO73_02109 ENOG4105JVW ECTO73_02110 ENOG4108393 oxidoreductase Fe-S subunit ECTO73_02111 ENOG4108NWD Cytochrome ECTO73_02112 ENOG4108Y7C Conserved Protein ECTO73_02113 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain ECTO73_02114 ENOG4105N0V mono-oxygenase ydhR ECTO73_02120 ENOG4108R6K riboflavin synthase, subunit alpha ECTO73_02121 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase ECTO73_02122 ENOG4105CZQ inner membrane transport protein YdhC ECTO73_02123 ENOG4105F52 Transcriptional regulator ECTO73_02127 ENOG4105F27 Major Facilitator ECTO73_02128 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ECTO73_02129 ENOG4105K4H Nlp p60 protein ECTO73_02130 ENOG4105M2J Glutaredoxin ECTO73_02131 ENOG4107QRT dEAD DEAH box helicase ECTO73_02132 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) ECTO73_02133 ENOG4108UYE Lactoylglutathione lyase ECTO73_02134 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ECTO73_02135 ENOG4108WUH Transcriptional regulator, TetR family ECTO73_02136 ENOG4105XZD Fe-S protein ECTO73_02137 ENOG4107RGM aldo keto reductase ECTO73_02138 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ECTO73_02139 ENOG4105DSW Fusaric acid resistance protein ECTO73_02140 ENOG4105Y49 secretion protein, HlyD family ECTO73_02143 ENOG4108XTF Outer Membrane Lipoprotein ECTO73_02145 ENOG410642K Lysozyme inhibitor ECTO73_02148 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) ECTO73_02149 ENOG4108K3A Glutathione S-transferase ECTO73_02150 ENOG4105DUX Transporter ECTO73_02152 ENOG4105CSM endonuclease III ECTO73_02154 ENOG4108UQQ Electron transport complex ECTO73_02159 ENOG4105M9B inner membrane protein ydgK ECTO73_02160 ENOG4105QZ5 OriC-binding nucleoid-associated protein ECTO73_02161 ENOG4105D9R oxidoreductase ECTO73_02163 ENOG4105C87 Aminotransferase class I and II ECTO73_02164 ENOG4105CI1 PTS System ECTO73_02165 ENOG4107P2S Transcriptional regulator ECTO73_02166 ENOG4107ZQV short-chain dehydrogenase reductase ECTO73_02167 ENOG4105XEA Tetr family transcriptional regulator ECTO73_02168 ENOG4105CNT hydrolase family 2 ECTO73_02169 ENOG4105CT4 transporter ECTO73_02170 ENOG4108QNI outer membrane porin protein ECTO73_02172 ENOG4106J39 exported protein ECTO73_02173 ENOG4105EIP mannose-6-phosphate isomerase ECTO73_02174 ENOG4107GFK fumarate ECTO73_02175 ENOG4105C9Q fumarate hydratase class II ECTO73_02177 ENOG4105JJR Histidine kinase ECTO73_02178 ENOG4107EXC regulatoR ECTO73_02179 ENOG4105RA2 Membrane ECTO73_02180 ENOG410642E Short chain dehydrogenase ECTO73_02181 ENOG4105D5Q Arginine ornithine antiporter ECTO73_02182 ENOG4105C5D exported protein ECTO73_02183 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ECTO73_02184 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ECTO73_02185 ENOG4105DSF transport protein ECTO73_02188 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap ECTO73_02190 ENOG4105D94 Major Facilitator Superfamily ECTO73_02191 ENOG4106NZI LysR family Transcriptional regulator ECTO73_02192 ENOG4105DAG ROK family ECTO73_02193 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) ECTO73_02195 ENOG4108NEM leader-binding protein dmsD ECTO73_02196 ENOG4107KGK dmso reductase anchor subunit ECTO73_02197 ENOG4105QAX Iron-sulfur ECTO73_02198 ENOG4105C3J Cysteine desulfurase ECTO73_02199 ENOG4107QY8 reductase ECTO73_02200 ENOG4105KBG Protein of unknown function (DUF1161) ECTO73_02202 ENOG4108MK9 spermidine N(1)-acetyltransferase ECTO73_02205 ENOG4105CXK mandelate racemase muconate lactonizing ECTO73_02206 ENOG4105CPQ Dehydrogenase ECTO73_02207 ENOG4107R08 Integrase ECTO73_02210 ENOG4106G8A Qin prophage ECTO73_02217 ENOG41087BU transcriptional repressor DicA ECTO73_02220 ENOG4105YQ0 ECTO73_02223 ENOG4105E5H Transposase ECTO73_02224 ENOG4108YXQ IS66 Orf2 family protein ECTO73_02232 ENOG4105K4U addiction module toxin, RelE StbE family ECTO73_02233 ENOG4105WI6 cell killing protein encoded within cryptic prophage ECTO73_02235 ENOG4108MXB Protein of unknown function (DUF968) ECTO73_02236 ENOG4105HGD Antitermination protein ECTO73_02239 ENOG4105VEQ Cold shock protein ECTO73_02241 ENOG4105QFS Lysis protein S homolog from lambdoid prophage ECTO73_02244 ENOG4108YV9 Protein of unknown function (DUF2514) ECTO73_02246 ENOG4105VEQ Cold shock protein ECTO73_02247 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation ECTO73_02248 ENOG41064WM Uncharacterized protein YcgX ECTO73_02249 ENOG4105FKG DNA packaging protein ECTO73_02250 ENOG4105UZW Tail fiber assembly protein ECTO73_02251 ENOG4107DE1 head-to-tail joining protein ECTO73_02253 ENOG4105F7J membrane-bound serine protease ECTO73_02256 ENOG4105DFP Integrase ECTO73_02268 ENOG4105IM0 capsid protein ECTO73_02272 ENOG4105IM0 capsid protein ECTO73_02288 ENOG410685N tail fiber protein ECTO73_02289 ENOG4105UZW Tail fiber assembly protein ECTO73_02291 ENOG4105MN3 Resolvase ECTO73_02292 ENOG4105W3V DNA-binding, transcriptional regulator ECTO73_02294 ENOG4105DEI Mannitol dehydrogenase ECTO73_02295 ENOG41061EV selenium-binding protein YdfZ ECTO73_02296 ENOG4107XBN GntR Family Transcriptional Regulator ECTO73_02297 ENOG4105EMU Dehydrogenase ECTO73_02298 ENOG4105DGW oligopeptidase A ECTO73_02299 ENOG4105DGW oligopeptidase A ECTO73_02300 ENOG4108WTK competence damage-inducible protein ECTO73_02301 ENOG4108YDI single-species biofilm formation on inanimate substrate ECTO73_02302 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria ECTO73_02305 ENOG4105E5W Transporter ECTO73_02306 ENOG4108594 Permease of the drug metabolite transporter ECTO73_02307 ENOG4106DNR multiple antibiotic resistance protein ECTO73_02308 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF ECTO73_02309 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes ECTO73_02313 ENOG4105EGI Transcriptional regulator ECTO73_02314 ENOG4105C26 Dehydrogenase ECTO73_02315 ENOG4105CSV Glutaminase ECTO73_02316 ENOG4105M0C cytoplasmic protein ECTO73_02317 ENOG4105BZU Histidine kinase ECTO73_02318 ENOG4107QZW Altronate oxidoreductase ECTO73_02319 ENOG4105FFC UPF0187 protein ECTO73_02321 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound ECTO73_02322 ENOG41061GT Aldolase ECTO73_02323 ENOG4105D4B ABC, transporter ECTO73_02324 ENOG4105F5R ABC transporter ECTO73_02325 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane ECTO73_02326 ENOG4105C2J ABC transporter ECTO73_02327 ENOG4105DKT Transcriptional regulator ECTO73_02328 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) ECTO73_02331 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein ECTO73_02332 ENOG4105CAF HipA N-terminal domain protein ECTO73_02341 ENOG4105MQ5 zona occludens toxin ECTO73_02355 ENOG4105MQ5 zona occludens toxin ECTO73_02361 ENOG4108WDE Fimbrial protein ECTO73_02362 ENOG4106318 fimbrial-like protein YdeR ECTO73_02363 ENOG4106PIH fimbrial-like protein ydeQ ECTO73_02364 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit ECTO73_02366 ENOG4105Z68 AraC Family Transcriptional Regulator ECTO73_02367 ENOG4105ENH Sulfatase ECTO73_02368 ENOG4105C4X radical SAM domain protein ECTO73_02369 ENOG4105CQ0 ABC transporter ECTO73_02370 ENOG4105PE1 Receptor ECTO73_02371 ENOG4107RAN Peptidase, M16 ECTO73_02372 ENOG4105CVK Glutamate decarboxylase ECTO73_02373 ENOG4105E5D amino acid ECTO73_02374 ENOG4105F32 YngK protein ECTO73_02375 ENOG4105BZU Histidine kinase ECTO73_02376 ENOG4105BZU Histidine kinase ECTO73_02377 ENOG4108UQS dipeptidase ECTO73_02378 ENOG4105DEF Extracellular solute-binding protein, family 5 ECTO73_02379 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ECTO73_02380 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ECTO73_02381 ENOG4105C3U ABC transporter ECTO73_02382 ENOG4107H6U ABC transporter ECTO73_02383 ENOG4108Z9K Osmotically inducible protein ECTO73_02384 ENOG4105TPS biofilm-dependent modulation protein ECTO73_02385 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein ECTO73_02387 ENOG4105DQ4 alcohol dehydrogenase ECTO73_02388 ENOG41084S7 Plasmid maintenance system antidote protein ECTO73_02389 ENOG4108MG3 formate dehydrogenase ECTO73_02390 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ECTO73_02391 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_02393 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_02394 ENOG4105RPH Inner membrane protein YddG ECTO73_02396 ENOG4108UI3 Leucine Rich repeat ECTO73_02397 ENOG4108UI3 Leucine Rich repeat ECTO73_02399 ENOG4107QND Nitrite extrusion protein ECTO73_02400 ENOG4105CRU nitrate reductase, alpha subunit ECTO73_02401 ENOG4105CRU nitrate reductase, alpha subunit ECTO73_02402 ENOG4108IUE nitrate reductase beta subunit ECTO73_02403 ENOG4108NZN Respiratory nitrate reductase 2 delta chain ECTO73_02404 ENOG4105D0D Nitrate reductase 2, gamma subunit ECTO73_02405 ENOG4105JAB phenazine biosynthesis protein, phzf family ECTO73_02406 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase ECTO73_02407 ENOG4108MEJ flavin reductase domain protein ECTO73_02409 ENOG410600T transposase ECTO73_02412 ENOG4105CNA YD repeat protein ECTO73_02413 ENOG4105CS6 Rhs element vgr protein ECTO73_02415 ENOG4108N27 Glutathione S-transferase ECTO73_02416 ENOG4105C85 amino acid ECTO73_02417 ENOG4108NS2 receptor ECTO73_02418 ENOG4105CHB tonB-dependent Receptor ECTO73_02419 ENOG4108ZSJ is1 orf2 ECTO73_02421 ENOG4108WYP Transcriptional regulator ECTO73_02422 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein ECTO73_02423 ENOG4108Z7F N-acetyltransferase ECTO73_02424 ENOG4108T9Y Inner membrane protein ydcZ ECTO73_02425 ENOG4105R71 cytoplasmic protein ECTO73_02426 ENOG410654E Membrane ECTO73_02428 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component ECTO73_02429 ENOG4105D81 ABC transporter, permease ECTO73_02430 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ECTO73_02431 ENOG4107TYH extracellular solute-binding protein family 1 ECTO73_02432 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ECTO73_02433 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin ECTO73_02435 ENOG4105RR0 Protein of unknown function (DUF2554) ECTO73_02436 ENOG4105CFP Peptidase U32 ECTO73_02437 ENOG4108JCI Transcriptional regulator ECTO73_02438 ENOG4105DKK Benzoate ECTO73_02439 ENOG4105D7V transposase ECTO73_02440 ENOG4108RS6 transposase ECTO73_02441 ENOG4108KKZ (LipO)protein ECTO73_02442 ENOG41088CC tellurite resistance protein tehB ECTO73_02443 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein ECTO73_02444 ENOG4107WE3 acetyltransferase YdcK ECTO73_02445 ENOG4108Z9I -acetyltransferase ECTO73_02446 ENOG4105Z2P Protein of unknown function (DUF465) ECTO73_02448 ENOG4105E32 cytoplasmic protein ECTO73_02449 ENOG4105DDW LysR family Transcriptional regulator ECTO73_02450 ENOG4105C8Q Methyl-accepting chemotaxis ECTO73_02453 ENOG4105UPP uncharacterized protein ydcA ECTO73_02455 ENOG4105CPW cytochrome b561 ECTO73_02456 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ECTO73_02457 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ECTO73_02458 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ECTO73_02459 ENOG4105C26 Dehydrogenase ECTO73_02460 ENOG4107DB1 DUF218 domain ECTO73_02461 ENOG4105CQ7 ATP-dependent helicase ECTO73_02463 ENOG41077RS Phosphatase ECTO73_02464 ENOG4105E8V Alpha Beta Hydrolase Fold protein ECTO73_02465 ENOG4108HPI phosphatidate Cytidylyltransferase ECTO73_02466 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase ECTO73_02468 ENOG4107S5I aldo keto reductase ECTO73_02469 ENOG4107EF2 surface-exposed virulence protein ECTO73_02470 ENOG41090WB Transposase is3 is911 ECTO73_02473 ENOG4108Z0R Transferase ECTO73_02474 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein ECTO73_02475 ENOG4105DZS Phenylacetate-CoA ligase ECTO73_02476 ENOG4105CHU acetyl-coa acetyltransferase ECTO73_02477 ENOG4108ZJI phenylacetic acid degradation protein ECTO73_02478 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ECTO73_02479 ENOG4108UKI Enoyl-CoA hydratase ECTO73_02480 ENOG4105E39 Enoyl-CoA hydratase ECTO73_02481 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ECTO73_02482 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit ECTO73_02483 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit ECTO73_02484 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit ECTO73_02485 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit ECTO73_02486 ENOG4105DXM phenylacetic acid degradation protein ECTO73_02487 ENOG4105F11 amine oxidase ECTO73_02488 ENOG4105C26 Dehydrogenase ECTO73_02489 ENOG4108WFR AraC Family Transcriptional Regulator ECTO73_02490 ENOG4105WXT Conserved Protein ECTO73_02491 ENOG410689M (LipO)protein ECTO73_02492 ENOG4107H52 Dicarboxylate transport ECTO73_02493 ENOG4105C5I Dehydrogenase ECTO73_02494 ENOG41090X5 Heat shock protein hslJ ECTO73_02496 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) ECTO73_02498 ENOG4105FCK Membrane ECTO73_02499 ENOG4108RW8 Universal stress protein F ECTO73_02501 ENOG4105C1J atp-dependent rna helicase ECTO73_02505 ENOG4105BZU Histidine kinase ECTO73_02506 ENOG4108DG9 Smr protein MutS2 ECTO73_02508 ENOG4106KR7 LysR family Transcriptional regulator ECTO73_02509 ENOG4105CH2 amidohydrolase ECTO73_02510 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B ECTO73_02511 ENOG4105CFC Transporter ECTO73_02512 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ECTO73_02513 ENOG4105DS0 Transcriptional regulator, Crp Fnr family ECTO73_02514 ENOG4105Q9Y Universal stress protein ECTO73_02515 ENOG4105S5I Membrane ECTO73_02516 ENOG4105D64 Mechanosensitive ion channel ECTO73_02517 ENOG4107QSI ABC, transporter ECTO73_02518 ENOG4105EQ2 LysR family Transcriptional regulator ECTO73_02519 ENOG4105ENX hydrolase ECTO73_02521 ENOG4105KXI murein peptide amidase A ECTO73_02522 ENOG4107S8C mandelate racemase muconate lactonizing ECTO73_02523 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) ECTO73_02524 ENOG4108JU8 Transcriptional regulator ECTO73_02526 ENOG4105CM6 amino acid regulated cytosolic protein ECTO73_02527 ENOG4105FKQ transcriptional regulator ECTO73_02528 ENOG4107EFV Outer membrane protein G ECTO73_02529 ENOG4108IJ9 (ABC) transporter ECTO73_02530 ENOG4107URF beta-phospho-glucomutase ECTO73_02531 ENOG4105C71 hydrolase family 65, central catalytic ECTO73_02532 ENOG4105CK5 oxidoreductase ECTO73_02533 ENOG4107TYA transient receptor potential locus ECTO73_02534 ENOG4107RRD Dehydrogenase ECTO73_02535 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component ECTO73_02536 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component ECTO73_02537 ENOG4105WEM extracellular solute-binding protein ECTO73_02538 ENOG4107QW3 Sucrose phosphorylase ECTO73_02539 ENOG4105K8Z Phage shock protein ECTO73_02540 ENOG4105NNG Peripheral inner membrane phage-shock protein ECTO73_02541 ENOG4105FM1 phage shock protein C ECTO73_02542 ENOG4105YYT phage shock protein B ECTO73_02543 ENOG41087YS Phage shock protein A ECTO73_02544 ENOG4105E51 psp operon transcriptional activator ECTO73_02545 ENOG4108JPW Aminotransferase ECTO73_02546 ENOG4105CJP fad dependent oxidoreductase ECTO73_02547 ENOG4105C26 Dehydrogenase ECTO73_02548 ENOG4107VRI Transcriptional regulator ECTO73_02549 ENOG4108Z86 Glutamine amidotransferase ECTO73_02550 ENOG4105CFQ glutamine synthetase ECTO73_02551 ENOG4105CUB amino acid ECTO73_02552 ENOG4105N0E Protein of unknown function (DUF2543) ECTO73_02553 ENOG4108HIY periplasmic ECTO73_02554 ENOG4108I5W peptide transport system, permease protein ECTO73_02555 ENOG4108EU3 peptide transport system, permease ECTO73_02556 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein ECTO73_02557 ENOG4108JQ2 peptide transport system atp-binding protein ECTO73_02558 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH ECTO73_02559 ENOG4105Q4T oxidoreductase ECTO73_02561 ENOG4105BZU Histidine kinase ECTO73_02563 ENOG4105N2W Transcriptional regulator ECTO73_02564 ENOG41061RM osmotically inducible lipoprotein ECTO73_02565 ENOG4108ZJT translation initiation factor, Sui1 ECTO73_02567 ENOG4105CFV Tetratricopeptide repeat protein ECTO73_02568 ENOG4105Q4A inner membrane protein yciS ECTO73_02569 ENOG4105EYK Phosphatidylglycerophosphatase B ECTO73_02571 ENOG4107QM5 aconitate hydratase ECTO73_02578 ENOG4107R11 Transcriptional regulator ECTO73_02579 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ECTO73_02580 ENOG4105RKX Protein of unknown function (DUF2498) ECTO73_02581 ENOG4105ERU peptidase ECTO73_02582 ENOG4105UBK short-chain dehydrogenase reductase ECTO73_02583 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase ECTO73_02584 ENOG4105FE9 pseudouridine synthase ECTO73_02585 ENOG4105EG3 transmembrane signal peptide protein ECTO73_02586 ENOG4107RTD sua5 ycio yrdc ywlc family protein ECTO73_02587 ENOG4105DB7 PHP domain protein ECTO73_02589 ENOG4105CRQ synthase (Component I) ECTO73_02590 ENOG4108EFP Anthranilate synthase component II ECTO73_02591 ENOG4105DK0 Indole-3-glycerol phosphate synthase ECTO73_02595 ENOG4108Z9Z response to DNA damage stimulus ECTO73_02596 ENOG4108N8X transition metal ion binding ECTO73_02597 ENOG4105EIF outer membrane protein W ECTO73_02600 ENOG4105NAU thioesterase Superfamily protein ECTO73_02601 ENOG410822N TonB family ECTO73_02602 ENOG4105K9H YciI-like protein ECTO73_02603 ENOG4107SVH Potassium channel protein ECTO73_02607 ENOG4108JQ7 (ABC) transporter ECTO73_02608 ENOG4105C3U ABC transporter ECTO73_02609 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ECTO73_02611 ENOG4108J59 Extracellular solute-binding protein, family 5 ECTO73_02614 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein ECTO73_02615 ENOG4108EKI Dehydrogenase ECTO73_02618 ENOG4107104 thymidine kinase ECTO73_02619 ENOG4108SAU DNA-binding protein H-ns ECTO73_02620 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ECTO73_02621 ENOG4105I93 response regulator ECTO73_02622 ENOG4105D78 K07001 NTE family protein ECTO73_02624 ENOG4105CIY formyltetrahydrofolate deformylase ECTO73_02629 ENOG41076YT nitrate reductase, gamma subunit ECTO73_02630 ENOG4105R3A Nitrate reductase ECTO73_02631 ENOG4108IUE nitrate reductase beta subunit ECTO73_02632 ENOG4105CRU nitrate reductase, alpha subunit ECTO73_02633 ENOG4105DQQ Major facilitator superfamily MFS_1 ECTO73_02635 ENOG4105BZU Histidine kinase ECTO73_02636 ENOG4105WH1 Two component transcriptional regulator luxr family ECTO73_02637 ENOG4105ID0 Putative invasin ECTO73_02638 ENOG41090EX DsrE family ECTO73_02639 ENOG4108NH8 Cation transport protein ECTO73_02640 ENOG4105WS7 Cation transport regulator ECTO73_02641 ENOG4105EWV Sodium calcium exchanger membrane region ECTO73_02649 ENOG41063JG Transcriptional regulator ECTO73_02650 ENOG4108YY7 Invasion gene expression up-regulator SirB ECTO73_02651 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ECTO73_02653 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) ECTO73_02655 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) ECTO73_02656 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ECTO73_02657 ENOG4105CHH sulfate transporter ECTO73_02658 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria ECTO73_02660 ENOG4105C3G gtp-binding protein ECTO73_02662 ENOG4105I1J Autotransporter ECTO73_02663 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family ECTO73_02664 ENOG4105CMT Dihydroxyacetone kinase ECTO73_02665 ENOG4108UTZ Dihydroxyacetone kinase ECTO73_02666 ENOG4105VDH Dihydroxyacetone kinase ECTO73_02669 ENOG4105Y3U Transglycosylase-associated protein ECTO73_02670 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) ECTO73_02672 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A ECTO73_02675 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ECTO73_02677 ENOG4105ED1 spovr family ECTO73_02680 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) ECTO73_02681 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ECTO73_02682 ENOG4105KT5 UmuD protein ECTO73_02684 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells ECTO73_02686 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase ECTO73_02688 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium ECTO73_02689 ENOG4105S66 prophage protein ECTO73_02691 ENOG4107QMS site-determining protein ECTO73_02693 ENOG4105D70 Integrase catalytic subunit ECTO73_02694 ENOG4105F5W AtP-binding protein ECTO73_02696 ENOG410658X ECTO73_02697 ENOG410658X ECTO73_02701 ENOG4105BZU Histidine kinase ECTO73_02702 ENOG410738I uncharacterized protein ymgC ECTO73_02704 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component ECTO73_02705 ENOG4105BZU Histidine kinase ECTO73_02706 ENOG4108XDN Transcriptional regulator ECTO73_02707 ENOG41064WM Uncharacterized protein YcgX ECTO73_02708 ENOG4108HMX isocitrate dehydrogenase (NADP) ECTO73_02709 ENOG4108R99 pseudouridine synthase ECTO73_02713 ENOG4107QTF adenylosuccinate lyase ECTO73_02714 ENOG4105XJC Two component transcriptional regulator (Winged helix family ECTO73_02715 ENOG4105IFJ Histidine kinase ECTO73_02716 ENOG4105EZE Cupin 4 family protein ECTO73_02718 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ECTO73_02719 ENOG4105F38 ABC transporter, permease ECTO73_02720 ENOG4105D38 putrescine abc transporter ECTO73_02721 ENOG4107RUE extracellular solute-binding protein family 1 ECTO73_02724 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ECTO73_02726 ENOG4105D60 lipoprotein releasing system transmembrane protein ECTO73_02727 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) ECTO73_02728 ENOG4105D60 lipoprotein releasing system transmembrane protein ECTO73_02729 ENOG4105IQC Inner membrane protein YcfT ECTO73_02730 ENOG4108JA2 transcriptioN-repair coupling factor ECTO73_02731 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ECTO73_02732 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction ECTO73_02733 ENOG4108IND Tetr family transcriptional regulator ECTO73_02734 ENOG4107MBR 17 kDa surface antigen ECTO73_02735 ENOG4105CEP NADH dehydrogenase ECTO73_02739 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) ECTO73_02740 ENOG41090DQ Lipoprotein ECTO73_02741 ENOG4105K59 histidine triad (HIT) protein ECTO73_02742 ENOG4105CNM Receptor ECTO73_02743 ENOG4105CI1 PTS System ECTO73_02744 ENOG4105F8V Hydrolase, tatD family ECTO73_02745 ENOG4107QRG dna polymerase iii ECTO73_02747 ENOG4105HHA aminodeoxychorismate lyase ECTO73_02748 ENOG4105YAZ 4-amino-4-deoxychorismate lyase ECTO73_02749 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ECTO73_02750 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) ECTO73_02751 ENOG4105CHR reductase ECTO73_02752 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ECTO73_02756 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein ECTO73_02758 ENOG4108UHJ MAF-like protein ECTO73_02759 ENOG4105EI2 Pseudouridine synthase ECTO73_02763 ENOG4107QQB Ribonuclease E ECTO73_02764 ENOG4105DTJ flagellar hook-associated protein ECTO73_02765 ENOG4105E1Q flagellar hook-associated protein ECTO73_02766 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj ECTO73_02769 ENOG4105CGA flagellar basal-body rod protein FlgG ECTO73_02770 ENOG4108KPB Flagellar basal-body rod protein FlgF ECTO73_02771 ENOG4105BZE flagellar hook protein, FlgE ECTO73_02772 ENOG4105W00 Flagellar hook capping protein ECTO73_02773 ENOG4108ZC9 flagellar basal-body rod protein flgc ECTO73_02774 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) ECTO73_02775 ENOG4105CKS Flagella basal body P-ring formation protein flgA ECTO73_02776 ENOG4105M9M anti-sigma28 factor FlgM ECTO73_02777 ENOG4105QVD Flagella synthesis protein FlgN ECTO73_02778 ENOG4105CJR Integral membrane protein (MviN ECTO73_02779 ENOG4105EP9 oxidoreductase ECTO73_02781 ENOG4105D9U N-acetyltransferase ECTO73_02783 ENOG4105E9S glutaredoxin 2 ECTO73_02784 ENOG4105F3T (LipO)protein ECTO73_02786 ENOG4105MEA DNA damage-inducible protein i ECTO73_02787 ENOG4105PVA Biofilm formation regulatory protein BssS ECTO73_02789 ENOG4106974 biofilm formation ECTO73_02790 ENOG4105DS1 cytochrome b561 ECTO73_02791 ENOG4108YYC ycei family ECTO73_02793 ENOG4105D1S lipid A biosynthesis ECTO73_02795 ENOG4108W47 Acidic protein msyB ECTO73_02796 ENOG4105NAC (LipO)protein ECTO73_02797 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) ECTO73_02800 ENOG4107RZC phospholipase d ECTO73_02801 ENOG4108UVJ appr-1-p processing domain protein ECTO73_02803 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) ECTO73_02804 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin ECTO73_02805 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers ECTO73_02806 ENOG41086KC Transcriptional regulator ECTO73_02807 ENOG4108XDW curli assembly protein CsgE ECTO73_02808 ENOG4108WYR Curli production assembly transport component, CsgF ECTO73_02809 ENOG4105P8Q Curli production assembly transport component CsgG ECTO73_02810 ENOG4108UQ5 membrane protein YcdZ ECTO73_02811 ENOG4107XHZ cytoplasmic chaperone TorD family protein ECTO73_02815 ENOG4108T85 Membrane ECTO73_02817 ENOG41090WB Transposase is3 is911 ECTO73_02819 ENOG4105BZU Histidine kinase ECTO73_02820 ENOG4108TUY outer membrane protein PgaA ECTO73_02821 ENOG4107BJW polysaccharide deacetylase ECTO73_02822 ENOG4105CND Glycosyl transferase, family 2 ECTO73_02823 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD ECTO73_02824 ENOG4105D5M phosphate starvation-inducible protein ECTO73_02825 ENOG4105DBE peroxidase ECTO73_02826 ENOG410650H (LipO)protein ECTO73_02827 ENOG4105EKT )-iron permease ECTO73_02828 ENOG4105CK7 Sodium proline symporter ECTO73_02829 ENOG4105C26 Dehydrogenase ECTO73_02830 ENOG4108R86 Transcriptional regulator ECTO73_02834 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) ECTO73_02837 ENOG4105C2W permease ECTO73_02838 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 ECTO73_02840 ENOG4105XH3 ECTO73_02841 ENOG4105D6F Phosphatase ECTO73_02845 ENOG4108SBI Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) ECTO73_02846 ENOG4107QY8 reductase ECTO73_02847 ENOG4105CUW cytochrome C-TYPE protein ECTO73_02848 ENOG4106WF9 DNA-binding transcriptional regulator TorR ECTO73_02849 ENOG4108SV3 Tmao reductase system periplasmic protein tort ECTO73_02850 ENOG4105BZU Histidine kinase ECTO73_02851 ENOG4105HEE Binding Domain protein ECTO73_02852 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation ECTO73_02854 ENOG4105VEQ Cold shock protein ECTO73_02856 ENOG4108Y9B (LipO)protein ECTO73_02857 ENOG4108W78 Pfam:DUF1017 ECTO73_02858 ENOG4105E3R (LipO)protein ECTO73_02859 ENOG4105DAY polysaccharide export protein ECTO73_02860 ENOG4107ZF2 Phosphatase ECTO73_02861 ENOG4105D75 Capsular exopolysaccharide family ECTO73_02863 ENOG4105D6F Phosphatase ECTO73_02865 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ECTO73_02866 ENOG4105C4M (Ubiquinol oxidase) subunit I ECTO73_02867 ENOG4105MVP hydrogenase-1 operon protein HyaF ECTO73_02868 ENOG4108VXY Hydrogenase-1 operon protein HyaE ECTO73_02869 ENOG4108USZ hydrogenase ECTO73_02870 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit ECTO73_02871 ENOG4105DPX Hydrogenase, large subunit ECTO73_02872 ENOG4105E3S small subunit ECTO73_02874 ENOG4108MN8 Membrane ECTO73_02875 ENOG4108Z0T Part of a sulfur-relay system (By similarity) ECTO73_02876 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 ECTO73_02879 ENOG4105K4P CoA-binding domain protein ECTO73_02882 ENOG41088T4 Helicase IV ECTO73_02883 ENOG410901E Membrane ECTO73_02884 ENOG4105EM2 membrane ECTO73_02885 ENOG4108RZ1 DNA transformation protein ECTO73_02887 ENOG4105UYK outer membrane protein a ECTO73_02889 ENOG4105DAN ATP-dependent protease ECTO73_02891 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) ECTO73_02892 ENOG4108Q2G (LipO)protein ECTO73_02893 ENOG4105DY2 Paraquat-inducible protein b ECTO73_02894 ENOG4105F1S paraquat-inducible protein a ECTO73_02895 ENOG4105C5H ABC transporter ECTO73_02896 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) ECTO73_02897 ENOG4105QVC MOSC domain-containing protein ECTO73_02898 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) ECTO73_02900 ENOG4106PH7 chaperone ECTO73_02901 ENOG4105MX3 Fimbrial ECTO73_02902 ENOG4105Q7J Fimbrial ECTO73_02903 ENOG4108MDY Fimbrial ECTO73_02904 ENOG4105CW0 outer membrane usher protein ECTO73_02905 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae ECTO73_02906 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon ECTO73_02907 ENOG4108UZX fmn reductase ECTO73_02908 ENOG4105GVF (ABC) transporter ECTO73_02910 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ECTO73_02911 ENOG4105E2Y ABC, transporter ECTO73_02912 ENOG4105CD8 aminopeptidase N ECTO73_02916 ENOG4105FCK Membrane ECTO73_02917 ENOG4105CGF Aromatic amino acid aminotransferase ECTO73_02918 ENOG4105C5X domain protein ECTO73_02919 ENOG4105EAQ (twin-arginine translocation) pathway signal ECTO73_02920 ENOG4105DIT ErfK YbiS YcfS YnhG family protein ECTO73_02922 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) ECTO73_02924 ENOG4106371 Methyltransferase ECTO73_02925 ENOG4107S90 membrAne ECTO73_02926 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups ECTO73_02929 ENOG4105T0Z Conserved Protein ECTO73_02930 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) ECTO73_02931 ENOG4105BZ1 (ABC) transporter ECTO73_02932 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 ECTO73_02934 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ECTO73_02936 ENOG4108K0D peptidase, M48 ECTO73_02939 ENOG4107VMU Membrane ECTO73_02940 ENOG4105DDY UPF0142 protein ycaO ECTO73_02941 ENOG4105TMB Formate nitrite transporter ECTO73_02942 ENOG4105C6N Formate acetyltransferase ECTO73_02943 ENOG4105ZTC transcriptional activator, Ogr delta ECTO73_02950 ENOG4108C33 Resolvase ECTO73_02952 ENOG4108US3 tail fiber assembly ECTO73_02953 ENOG4105UZW Tail fiber assembly protein ECTO73_02954 ENOG4105D70 Integrase catalytic subunit ECTO73_02955 ENOG4105F5W AtP-binding protein ECTO73_02978 ENOG4108C33 Resolvase ECTO73_02981 ENOG4105F5W AtP-binding protein ECTO73_02982 ENOG4105D70 Integrase catalytic subunit ECTO73_02983 ENOG4105UZW Tail fiber assembly protein ECTO73_02984 ENOG4108US3 tail fiber assembly ECTO73_03003 ENOG4105ED4 portal protein ECTO73_03006 ENOG4105VZ1 Replication Protein ECTO73_03015 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ECTO73_03016 ENOG4105F1A Pyruvate formate-lyase ECTO73_03017 ENOG4108X0B nad(p)h dehydrogenase (quinone) ECTO73_03018 ENOG410642W LysR family Transcriptional regulator ECTO73_03019 ENOG4105E5D amino acid ECTO73_03021 ENOG4105CHJ isochorismatase hydrolase ECTO73_03022 ENOG4107KGK dmso reductase anchor subunit ECTO73_03023 ENOG4105QAX Iron-sulfur ECTO73_03024 ENOG4107QY8 reductase ECTO73_03027 ENOG4105D1H recombination factor protein RarA ECTO73_03029 ENOG4105CNU cell division protein FtsK ECTO73_03030 ENOG4105EW9 transcriptional regulator AsnC family ECTO73_03031 ENOG4105C3M thioredoxin reductase ECTO73_03032 ENOG4108JJ9 ABC, transporter ECTO73_03033 ENOG4108JJ8 (ABC) transporter ECTO73_03035 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) ECTO73_03038 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ECTO73_03040 ENOG4105VEQ Cold shock protein ECTO73_03041 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) ECTO73_03042 ENOG4105DJY efflux transporter, rnd family, mfp subunit ECTO73_03043 ENOG4108MJ5 VirK protein ECTO73_03044 ENOG4105CPB ATP-dependent endonuclease of the OLD family ECTO73_03045 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ECTO73_03046 ENOG4105DWU Membrane ECTO73_03048 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ECTO73_03049 ENOG4105C7K acetolactate synthase ECTO73_03050 ENOG4105C5W Aldolase ECTO73_03051 ENOG4105CGD Nad-dependent epimerase dehydratase ECTO73_03052 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase ECTO73_03053 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ECTO73_03055 ENOG41064MM (LipO)protein ECTO73_03056 ENOG4105E5Z arginine transporter ATP-binding subunit ECTO73_03057 ENOG4106PMH Extracellular solute-binding protein family 3 ECTO73_03058 ENOG4105GBT ABC transporter ECTO73_03059 ENOG4105DMR ABC, transporter ECTO73_03060 ENOG4106TNF Periplasmic binding protein ECTO73_03062 ENOG4105RBQ inner membrane protein ybjO ECTO73_03063 ENOG4105D38 putrescine abc transporter ECTO73_03064 ENOG4105F38 ABC transporter, permease ECTO73_03065 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ECTO73_03066 ENOG4107RUE extracellular solute-binding protein family 1 ECTO73_03067 ENOG4108RMJ sensory transduction regulator ECTO73_03069 ENOG4108DBC nitroreductase ECTO73_03070 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress ECTO73_03071 ENOG41090BQ Glutaredoxin ECTO73_03072 ENOG4105GWF inner membrane protein YbjM ECTO73_03075 ENOG4108RFG Tetr family transcriptional regulator ECTO73_03076 ENOG4106UW1 Major Facilitator superfamily ECTO73_03077 ENOG4108HCJ Hydrolase ECTO73_03079 ENOG4107QF7 multi-drug ECTO73_03080 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ECTO73_03081 ENOG4107FB0 transcriptional regulator DeoR family ECTO73_03082 ENOG4105DZ1 carboxypeptidase ECTO73_03083 ENOG4108TGY Glutathione S-transferase ECTO73_03084 ENOG4105D8V Glucose sorbosone dehydrogenase ECTO73_03085 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway ECTO73_03087 ENOG41064RH membrane protein YliF ECTO73_03088 ENOG4105BZU Histidine kinase ECTO73_03089 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ECTO73_03091 ENOG4105DEF Extracellular solute-binding protein, family 5 ECTO73_03092 ENOG4108JQ6 ABC transporter ECTO73_03093 ENOG4105D44 asparaginase ECTO73_03094 ENOG4105CVM Molybdenum cofactor synthesis domain protein ECTO73_03095 ENOG4105D06 uba thif-type nad fad binding protein ECTO73_03096 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ECTO73_03097 ENOG4105F1A Pyruvate formate-lyase ECTO73_03098 ENOG4105C6N Formate acetyltransferase ECTO73_03099 ENOG4108HCJ Hydrolase ECTO73_03100 ENOG41072TH Protein of unknown function (DUF1479) ECTO73_03101 ENOG4105C5H ABC transporter ECTO73_03102 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ECTO73_03103 ENOG4105F4P )-transporter ECTO73_03104 ENOG4105KST dependent repressor ECTO73_03106 ENOG4108I6E Sulfatase ECTO73_03107 ENOG4108T1M outer membrane protein x ECTO73_03108 ENOG4107AQZ Membrane ECTO73_03110 ENOG4107R0W ABC transporter ECTO73_03111 ENOG4105E5Q amino acid AbC transporter ECTO73_03112 ENOG4105CDA abc transporter atp-binding protein ECTO73_03113 ENOG4105D8X mechanosensitive ion channel ECTO73_03115 ENOG4105ZY9 UPF0379 protein ybiM ECTO73_03116 ENOG4108IU3 tonb-dependent siderophore receptor ECTO73_03118 ENOG4105KSC Transcriptional regulator, TraR DksA family ECTO73_03119 ENOG4105VR4 UPF0379 protein ybiJ ECTO73_03120 ENOG4105DG4 malate L-lactate dehydrogenase ECTO73_03121 ENOG4108MTB glycosyl transferase family ECTO73_03122 ENOG4105DVT helicase ECTO73_03123 ENOG4108UV1 cellular component movement ECTO73_03124 ENOG4105C1J atp-dependent rna helicase ECTO73_03125 ENOG4107MVR Transcriptional regulator ECTO73_03127 ENOG4105CJ1 ABC, transporter ECTO73_03128 ENOG4107QWP ABC-2 type transporter ECTO73_03129 ENOG4107QWP ABC-2 type transporter ECTO73_03130 ENOG4105I9U inner membrane protein ybhQ ECTO73_03131 ENOG4105X23 Endonuclease Exonuclease phosphatase ECTO73_03132 ENOG4105DZQ phospholipase D Transphosphatidylase ECTO73_03133 ENOG4107UXM Membrane ECTO73_03134 ENOG410733J conserved inner membrane protein ECTO73_03135 ENOG4105HFZ Membrane ECTO73_03136 ENOG4108ZAF Molybdopterin ECTO73_03137 ENOG4105M00 molybdopterin converting factor, subunit 1 ECTO73_03139 ENOG4108RIR Molybdenum cofactor biosynthesis protein ECTO73_03142 ENOG4105CHW UPF0052 protein ECTO73_03144 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) ECTO73_03145 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ECTO73_03146 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ECTO73_03148 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ECTO73_03149 ENOG4108V1U phospholipid-binding protein ECTO73_03150 ENOG4105NBR Pectinesterase ECTO73_03151 ENOG4107QM5 aconitate hydratase ECTO73_03152 ENOG4107QPK )-transporter ECTO73_03153 ENOG4105C7F AcnD-accessory protein PrpF ECTO73_03154 ENOG4105F04 LysR family Transcriptional regulator ECTO73_03156 ENOG4108K4B hydrolase ECTO73_03157 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) ECTO73_03158 ENOG4105E0C molybdate abc transporter ECTO73_03159 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ECTO73_03160 ENOG410680R Protein of unknown function (DUF2592) ECTO73_03161 ENOG4105F4R Transcriptional regulator mode ECTO73_03162 ENOG4105DKW ABC transporter ECTO73_03163 ENOG4105CMR udp-glucose 4-epimerase ECTO73_03164 ENOG4105F0Z galactose-1-phosphate uridylyltransferase ECTO73_03166 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) ECTO73_03168 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ECTO73_03169 ENOG4105JND homeobox protein ECTO73_03170 ENOG4105PGM cation diffusion facilitator family transporter ECTO73_03171 ENOG4106Z1T Nicotinamide Mononucleotide Transporter ECTO73_03180 ENOG4105UFD tol-pal system protein YbgF ECTO73_03181 ENOG4105KCK Peptidoglycan-associated lipoprotein ECTO73_03183 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA ECTO73_03184 ENOG4105M8F Biopolymer transport protein exbD tolR ECTO73_03185 ENOG4105E02 MotA TolQ exbB proton channel ECTO73_03186 ENOG4107YD3 Thioesterase ECTO73_03187 ENOG4105KJB cyd operon protein YbgE ECTO73_03189 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ECTO73_03190 ENOG4105C4M (Ubiquinol oxidase) subunit I ECTO73_03191 ENOG4105C8I hydrolase, family 38 ECTO73_03192 ENOG4105DM4 PTS System ECTO73_03193 ENOG4105FDP GntR family transcriptional regulator ECTO73_03194 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ECTO73_03196 ENOG4105C7S Dehydrogenase ECTO73_03197 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 ECTO73_03198 ENOG4105E33 succinate dehydrogenase ECTO73_03199 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) ECTO73_03200 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein ECTO73_03201 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit ECTO73_03203 ENOG4105BZN citrate synthase ECTO73_03204 ENOG4106UBK fimbrial-like adhesin protein ECTO73_03205 ENOG4106PG1 outer membrane usher protein ECTO73_03206 ENOG4108TTM chaperone ECTO73_03207 ENOG4108MY7 Fimbrial ECTO73_03208 ENOG4108KK1 membrane protein AbrB duplication ECTO73_03211 ENOG4107R7A Allophanate hydrolase subunit 2 ECTO73_03212 ENOG4105P4J Allophanate hydrolase, subunit 1 ECTO73_03213 ENOG4107QNR UPF0135 protein ECTO73_03214 ENOG4105DUX Transporter ECTO73_03215 ENOG4105CVP deoxyribo-dipyrimidine photolyase ECTO73_03216 ENOG4107SEY Conserved Protein ECTO73_03217 ENOG410600T transposase ECTO73_03218 ENOG410600T transposase ECTO73_03219 ENOG410600T transposase ECTO73_03220 ENOG4106R09 ECTO73_03221 ENOG4105CNA YD repeat protein ECTO73_03222 ENOG41079JQ Membrane ECTO73_03223 ENOG4105CNA YD repeat protein ECTO73_03224 ENOG4105XIQ Protein of unknown function (DUF2517) ECTO73_03228 ENOG4105C08 Histidine kinase ECTO73_03229 ENOG4105EEX Two component transcriptional regulator (Winged helix family ECTO73_03231 ENOG4105CXN decarboxylase ECTO73_03232 ENOG4105CXN decarboxylase ECTO73_03233 ENOG4105CXN decarboxylase ECTO73_03234 ENOG4105D5Q Arginine ornithine antiporter ECTO73_03237 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 ECTO73_03238 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) ECTO73_03239 ENOG4105EV9 Alpha Beta Hydrolase ECTO73_03240 ENOG4105NNH LexA regulated protein ECTO73_03241 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) ECTO73_03242 ENOG41090R7 Ferric uptake ECTO73_03243 ENOG4105GX6 (LipO)protein ECTO73_03247 ENOG4105CI1 PTS System ECTO73_03249 ENOG4105CE4 GlcNAc 6-P deacetylase ECTO73_03250 ENOG4105E2R ROK family ECTO73_03251 ENOG4105D4U had-superfamily hydrolase, subfamily iia ECTO73_03252 ENOG4105CAQ asparagine synthetase ECTO73_03260 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ECTO73_03262 ENOG4105C9A Phoh family ECTO73_03264 ENOG4108JU5 Magnesium and cobalt efflux protein ECTO73_03265 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) ECTO73_03266 ENOG4107RP9 extracellular solute-binding protein, family 3 ECTO73_03268 ENOG4105EAD ABC transporter ECTO73_03269 ENOG4105DRP amino acid AbC transporter ECTO73_03270 ENOG4105CDA abc transporter atp-binding protein ECTO73_03272 ENOG4105F7F Chaperone ECTO73_03273 ENOG4105QFC Hsc56 co-chaperone of HscC ECTO73_03274 ENOG41069CF Protein of unknown function (DUF1266) ECTO73_03275 ENOG4107JFD Sel1 repeat ECTO73_03276 ENOG4105QFC Hsc56 co-chaperone of HscC ECTO73_03277 ENOG41069CF Protein of unknown function (DUF1266) ECTO73_03278 ENOG4105EUU Sel1 domain protein repeat-containing protein ECTO73_03279 ENOG4107PAI alpha helical protein ECTO73_03282 ENOG4105DJF DNA polymerase III, delta' subunit ECTO73_03284 ENOG4108TGR phosphatase ECTO73_03285 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) ECTO73_03287 ENOG4105CJN penicillin-binding protein ECTO73_03288 ENOG4105CNI cell division protein FtsW ECTO73_03289 ENOG4105K6T rare lipoprotein A ECTO73_03290 ENOG4105DZ1 carboxypeptidase ECTO73_03293 ENOG41064T2 transcriptional regulator, lysR family ECTO73_03295 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) ECTO73_03296 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ECTO73_03300 ENOG4105VEQ Cold shock protein ECTO73_03301 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) ECTO73_03302 ENOG4105CEE C4-dicarboxylate transporter ECTO73_03303 ENOG4106YYS transcriptional regulatory protein ECTO73_03304 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ECTO73_03305 ENOG4105DUA (citrate (pro-3S)-lyase ligase ECTO73_03307 ENOG4105CI0 Citrate lyase ECTO73_03308 ENOG4105CHY citrate lyase, alpha ECTO73_03311 ENOG4107QPK )-transporter ECTO73_03312 ENOG4105KTS ribonuclease ECTO73_03314 ENOG4105NXH GreA GreB family elongation factor ECTO73_03316 ENOG4105E2A Dehydrogenase ECTO73_03317 ENOG4108U51 Universal stress protein ECTO73_03318 ENOG4108JU3 Alkyl hydroperoxide reductase ECTO73_03319 ENOG4105D3R alkyl hydroperoxide reductase ECTO73_03320 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase ECTO73_03321 ENOG4105DQS Transcriptional regulator ECTO73_03322 ENOG4105BZV Phosphoadenosine phosphosulfate reductase ECTO73_03323 ENOG4105GTN ParB Domain Protein Nuclease ECTO73_03324 ENOG4105CHM Aminotransferase ECTO73_03325 ENOG4107SCQ Iron-containing alcohol dehydrogenase ECTO73_03326 ENOG4105VCD cytoplasmic protein ECTO73_03327 ENOG4105D22 carbon starvation protein ECTO73_03328 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) ECTO73_03329 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ECTO73_03330 ENOG4105WQI isochorismatase ECTO73_03331 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ECTO73_03332 ENOG4105E4F Isochorismate synthase ECTO73_03333 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein ECTO73_03335 ENOG4105DQ5 transport system permease protein ECTO73_03336 ENOG4105TVJ transport system, permease ECTO73_03337 ENOG4105E0A ABC, transporter ECTO73_03338 ENOG4108QY5 Ferric enterobactin transport protein ECTO73_03339 ENOG4105C0W non-ribosomal peptide synthetase ECTO73_03340 ENOG41085A6 mbth domain-containing protein ECTO73_03341 ENOG4105E93 esterase ECTO73_03342 ENOG4107RNH Outer membrane receptor FepA ECTO73_03343 ENOG4108TSE Transferase ECTO73_03345 ENOG4108SER Transposase ECTO73_03346 ENOG4107635 Hok Gef family protein ECTO73_03352 ENOG4105HVQ Regulatory factor of maltose metabolism ECTO73_03356 ENOG4107T8Q Glycosyl transferase (Group 1 ECTO73_03357 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) ECTO73_03358 ENOG4105CGN Glycosyl transferase (Group 1 ECTO73_03359 ENOG4105CPK Glycosyl transferase (Group 1 ECTO73_03363 ENOG4105CMR udp-glucose 4-epimerase ECTO73_03365 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ECTO73_03366 ENOG4105G1A colanic acid biosynthesis protein ECTO73_03368 ENOG4108RCM Nitroreductase ECTO73_03369 ENOG4105CUY Mechanosensitive ion channel ECTO73_03370 ENOG4105C85 amino acid ECTO73_03371 ENOG4108IJF Heavy metal efflux pump, CzcA ECTO73_03372 ENOG4105EP1 Efflux transporter rnd family, mfp subunit ECTO73_03373 ENOG410624V efflux system protein ECTO73_03374 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ECTO73_03375 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ECTO73_03376 ENOG4105GR3 Histidine kinase ECTO73_03377 ENOG410802X bacteriophage n4 adsorption protein b ECTO73_03378 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit ECTO73_03379 ENOG4105QUW ECTO73_03382 ENOG4108Q9V regulatoR ECTO73_03383 ENOG4108ZI2 Fimbrial protein ECTO73_03384 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) ECTO73_03385 ENOG4105CW0 outer membrane usher protein ECTO73_03386 ENOG4108AF8 Chaperone ECTO73_03387 ENOG4108WDE Fimbrial protein ECTO73_03389 ENOG4105WQ3 Rna-binding protein ECTO73_03390 ENOG4105S2T inner membrane protein YbcI ECTO73_03392 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ECTO73_03394 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ECTO73_03395 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ECTO73_03396 ENOG4105C5B carbamate kinase ECTO73_03397 ENOG4105G5A Protein of unknown function (DUF2877) ECTO73_03398 ENOG4107REC cytoplasmic protein ECTO73_03399 ENOG4107R1Q Membrane protein FdrA ECTO73_03400 ENOG4105DG4 malate L-lactate dehydrogenase ECTO73_03401 ENOG4105CE7 Amidase, hydantoinase carbamoylase family ECTO73_03402 ENOG4105S0E allantoin catabolism protein ECTO73_03404 ENOG4105S0E allantoin catabolism protein ECTO73_03406 ENOG4105BZW Glycerate kinase ECTO73_03407 ENOG4105DTE Xanthine uracil vitamin C permease ECTO73_03409 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ECTO73_03410 ENOG4108ZSJ is1 orf2 ECTO73_03412 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ECTO73_03413 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ECTO73_03414 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) ECTO73_03415 ENOG41060W2 glyoxylate carboligase ECTO73_03416 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region ECTO73_03417 ENOG4108Z2U ureidoglycolate hydrolase ECTO73_03418 ENOG4107653 Transcriptional regulator ECTO73_03420 ENOG4108J1Q ECTO73_03424 ENOG4105CNA YD repeat protein ECTO73_03425 ENOG4105CNA YD repeat protein ECTO73_03426 ENOG4105CV6 ABC transporter, permease ECTO73_03427 ENOG4108I0Y (ABC) transporter ECTO73_03428 ENOG4108UJV acyl-CoA thioesterase i ECTO73_03429 ENOG4105E1F short-chain dehydrogenase reductase ECTO73_03430 ENOG4107QR8 Thioredoxin ECTO73_03431 ENOG4105C4B ABC transporter, permease ECTO73_03432 ENOG41083J0 (ABC) transporter ECTO73_03433 ENOG4107QX8 SPFH domain, Band 7 family protein ECTO73_03434 ENOG4105G5H Membrane ECTO73_03435 ENOG4108Z6Z Transcriptional regulator ECTO73_03436 ENOG4107RY6 amino acid ECTO73_03437 ENOG4105CSV Glutaminase ECTO73_03438 ENOG4105C59 p-type ATPase ECTO73_03439 ENOG41081XE plasmid maintenance system antidote protein, xre family ECTO73_03440 ENOG4105MBR gumn family ECTO73_03442 ENOG4108Z66 YbaK ebsC protein ECTO73_03443 ENOG4105CGH 5'-nucleotidase ECTO73_03444 ENOG4105EU0 Major facilitator Superfamily ECTO73_03445 ENOG4105CKD glutathione-regulated potassium-efflux system protein ECTO73_03446 ENOG4107RE1 Inosine-guanosine kinase ECTO73_03450 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) ECTO73_03453 ENOG4107QMP dna polymerase iii subunits gamma and tau ECTO73_03456 ENOG4105WD1 Membrane ECTO73_03457 ENOG4108URS primosomal replication protein n'' ECTO73_03458 ENOG4106428 Protein of unknown function (DUF2496) ECTO73_03459 ENOG4105EGS Mechanosensitive ion channel ECTO73_03460 ENOG4108IG5 Transcriptional regulator ECTO73_03461 ENOG4105C1P efflux transporter, rnd family, mfp subunit ECTO73_03462 ENOG4105BZS acriflavin resistance protein ECTO73_03463 ENOG4108UKR Biofilm formation regulator YbaJ ECTO73_03464 ENOG4105KF5 hemolysin expression-modulating protein ECTO73_03465 ENOG4108UW5 maltose o-acetyltransferase ECTO73_03466 ENOG4105GSJ Inner membrane protein ylaC ECTO73_03467 ENOG41066DG (EAL) domain protein ECTO73_03468 ENOG4105KCV RNA signal recognition particle 4.5S RNA ECTO73_03470 ENOG41080UX Methyltransferase ECTO73_03471 ENOG4108MNP Glycoprotein polysaccharide metabolism ECTO73_03472 ENOG4105C29 acyl-CoA thioesterase ECTO73_03473 ENOG4105BZU Histidine kinase ECTO73_03474 ENOG4108YZA Nitrogen regulatory protein pii ECTO73_03475 ENOG4105BZ1 (ABC) transporter ECTO73_03476 ENOG4105BZ1 (ABC) transporter ECTO73_03477 ENOG4108XM1 transcriptional regulator AsnC family ECTO73_03479 ENOG4108NFA extracellular solute-binding protein ECTO73_03481 ENOG4108TGP Thioesterase superfamily protein ECTO73_03482 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein ECTO73_03483 ENOG4105EIN peptidylprolyl cis-trans isomerase ECTO73_03484 ENOG4105K70 DNA-binding protein ECTO73_03485 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) ECTO73_03490 ENOG4105M85 Bola protein ECTO73_03491 ENOG4105IEY (LipO)protein ECTO73_03492 ENOG4105EYM Major Facilitator superfamily ECTO73_03493 ENOG4105E2S oxidase) subunit II ECTO73_03494 ENOG4105BZ9 Cytochrome C oxidase, subunit I ECTO73_03495 ENOG4105CCU oxidase (Subunit III) ECTO73_03496 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) ECTO73_03498 ENOG4107RDB Major Facilitator ECTO73_03500 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) ECTO73_03501 ENOG4107S0N DJ-1 family ECTO73_03504 ENOG4105CTB Polyprenyl synthetase ECTO73_03506 ENOG4105CPC Aldo Keto reductase ECTO73_03507 ENOG4108ZAI phosphatidylglycerophosphatase a ECTO73_03508 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) ECTO73_03510 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) ECTO73_03511 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ECTO73_03513 ENOG4108KIC (LipO)protein ECTO73_03514 ENOG4105DRB nucleoside-specific channel-forming protein ECTO73_03515 ENOG4105N1F Hnh endonuclease ECTO73_03516 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ECTO73_03517 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ECTO73_03518 ENOG4105VIE preprotein translocase, subunit YajC ECTO73_03522 ENOG4107R28 alpha amylase, catalytic region ECTO73_03523 ENOG4105C85 amino acid ECTO73_03524 ENOG4105CWM branched-chain amino acid transport system II carrier protein ECTO73_03525 ENOG4105BZU Histidine kinase ECTO73_03526 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ECTO73_03527 ENOG4107RH8 nuclease SbcCD subunit D ECTO73_03528 ENOG4105EYH Exonuclease ECTO73_03529 ENOG4105F27 Major Facilitator ECTO73_03530 ENOG4105DKQ ROK family ECTO73_03534 ENOG4105HBA AroM protein ECTO73_03535 ENOG4105SS3 ECTO73_03538 ENOG4105II7 pyrroline-5-carboxylate reductase ECTO73_03539 ENOG4105BZU Histidine kinase ECTO73_03540 ENOG4105VIF phosphate starvation-inducible protein ECTO73_03541 ENOG4105G6Z alkaline phosphatase ECTO73_03543 ENOG4105CPF Cell wall formation (By similarity) ECTO73_03544 ENOG4105UNH Membrane ECTO73_03545 ENOG4105FR5 inner membrane protein YaiY ECTO73_03546 ENOG4107QS8 (LipO)protein ECTO73_03547 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 ECTO73_03549 ENOG4107R6D beta-lactam binding protein AmpH ECTO73_03550 ENOG4108PNB DNA-binding transcriptional regulator ECTO73_03552 ENOG4105D52 delta-aminolevulinic acid dehydratase ECTO73_03553 ENOG4105E2B Taurine dioxygenase ECTO73_03554 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ECTO73_03555 ENOG4108IY8 ABC, transporter ECTO73_03556 ENOG4106FTQ Taurine ABC transporter, periplasmic ECTO73_03557 ENOG4107W19 lmbE family ECTO73_03558 ENOG4108PBI Polysaccharide metabolism ECTO73_03559 ENOG4105SRB Uncharacterized protein yaiO ECTO73_03562 ENOG4105C4W S-formylglutathione hydrolase ECTO73_03563 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme ECTO73_03564 ENOG4108SC4 )-transporter ECTO73_03567 ENOG4105IKQ hydratase ECTO73_03568 ENOG4106HB6 Alpha beta hydrolase ECTO73_03569 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) ECTO73_03570 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase ECTO73_03571 ENOG4108K2P TRANSCRIPTIONal ECTO73_03572 ENOG4105ETE Transcriptional regulator (LacI family ECTO73_03573 ENOG4105CNT hydrolase family 2 ECTO73_03574 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) ECTO73_03575 ENOG4108UW5 maltose o-acetyltransferase ECTO73_03576 ENOG4105DJ2 Major Facilitator Superfamily ECTO73_03577 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) ECTO73_03578 ENOG4107B2H carbonic anhydrase ECTO73_03579 ENOG4105DND Transcriptional regulator ECTO73_03580 ENOG4105DZC cytosine deaminase ECTO73_03581 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin ECTO73_03582 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ECTO73_03583 ENOG4105DXD 2-methylcitrate dehydratase ECTO73_03584 ENOG4105BZN citrate synthase ECTO73_03586 ENOG4105CR4 methylisocitrate lyase ECTO73_03587 ENOG4108JU7 Transcriptional regulator ECTO73_03588 ENOG4105TDT uncharacterized protein yahO ECTO73_03589 ENOG4105E82 cytochrome subunit of dehydrogenase ECTO73_03592 ENOG4105DQ4 alcohol dehydrogenase ECTO73_03593 ENOG4105DZC cytosine deaminase ECTO73_03594 ENOG4105C5B carbamate kinase ECTO73_03596 ENOG4107REC cytoplasmic protein ECTO73_03597 ENOG4107R1Q Membrane protein FdrA ECTO73_03598 ENOG4105N16 Protein of unknown function (DUF2877) ECTO73_03599 ENOG4107SNB ankyrin repeat protein YahD ECTO73_03600 ENOG4105SZ2 membrAne ECTO73_03601 ENOG4108NUU Transcriptional regulator ECTO73_03602 ENOG4105BZU Histidine kinase ECTO73_03605 ENOG4105C94 Transporter ECTO73_03606 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) ECTO73_03607 ENOG4105C26 Dehydrogenase ECTO73_03608 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) ECTO73_03610 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) ECTO73_03611 ENOG4107QR9 Iron-sulfur cluster binding protein ECTO73_03612 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ECTO73_03613 ENOG4108K01 transcriptional regulator ECTO73_03614 ENOG4107QN2 dihydrolipoyl dehydrogenase ECTO73_03615 ENOG4108KBJ Inner membrane protein YkgB ECTO73_03620 ENOG4105NRA 50s ribosomal protein l31 type b ECTO73_03622 ENOG4106JB4 Represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility. Acts by binding to the regulatory region of the flhDC operon ECTO73_03623 ENOG4108GWT fimbrillin MatB ECTO73_03625 ENOG4108N3D putative enzyme ECTO73_03626 ENOG4106PYX Receptor ECTO73_03627 ENOG4108UD7 cell wall organization ECTO73_03629 ENOG4105R3P Inner membrane protein yagU ECTO73_03630 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit ECTO73_03631 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding ECTO73_03632 ENOG4105C7W Xanthine dehydrogenase ECTO73_03633 ENOG4107XAN XdhC and CoxI family ECTO73_03661 ENOG4105DFP Integrase ECTO73_03665 ENOG4105FCK Membrane ECTO73_03669 ENOG4105CIN aminoacyl-histidine dipeptidase ECTO73_03670 ENOG4108S2Y peptide Chain Release factor ECTO73_03672 ENOG4108HYG acetyltransferase ECTO73_03673 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome ECTO73_03674 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system ECTO73_03675 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ECTO73_03678 ENOG4108UK5 Transposase ECTO73_03679 ENOG4108YS0 lipoprotein YafL ECTO73_03680 ENOG4105QHH Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression ECTO73_03681 ENOG4105VXN addiction module toxin, RelE StbE family ECTO73_03682 ENOG4105F7V ErfK ybiS ycfS ynhG family protein ECTO73_03683 ENOG4105E7A Glutamine amidotransferase ECTO73_03685 ENOG4107QPN acyl-Coa dehydrogenase ECTO73_03686 ENOG4108WN0 inhibitor of vertebrate lysozyme ECTO73_03687 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ECTO73_03688 ENOG410600T transposase ECTO73_03691 ENOG4105CNA YD repeat protein ECTO73_03692 ENOG4105CS6 Rhs element vgr protein ECTO73_03693 ENOG4108WC9 type VI secretion system effector, hcp1 family ECTO73_03704 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ECTO73_03709 ENOG4105GMB type VI secretion system effector, hcp1 family ECTO73_03712 ENOG410600K aminopeptidase ECTO73_03714 ENOG4107RZZ dna polymerase iii epsilon subunit ECTO73_03716 ENOG4105D1A Methyltransferase ECTO73_03717 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ECTO73_03718 ENOG4105E9H Lytic Murein transglycosylase ECTO73_03719 ENOG4105F2W methyltransferase ECTO73_03721 ENOG4105HEI LysR family (Transcriptional regulator ECTO73_03722 ENOG4105CV8 reductase ECTO73_03730 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase ECTO73_03731 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ECTO73_03732 ENOG4108UMI ABC transporter, permease ECTO73_03733 ENOG4105D01 (LipO)protein ECTO73_03734 ENOG4108R8X outer membrane lipoprotein ECTO73_03735 ENOG4108R96 Methyltransferase, YaeB family ECTO73_03737 ENOG4108UY0 (LipO)protein ECTO73_03738 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion ECTO73_03739 ENOG4108YZN class I peptide chain release factor ECTO73_03740 ENOG4108VWS Yaeq family ECTO73_03742 ENOG4105M1T rho-binding antiterminator ECTO73_03743 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ECTO73_03744 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase ECTO73_03745 ENOG4105CXN decarboxylase ECTO73_03747 ENOG4105C0B DNA polymerase III (alpha subunit) ECTO73_03752 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ECTO73_03753 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) ECTO73_03755 ENOG4105DZP Membrane-associated zinc metalloprotease ECTO73_03756 ENOG4105KNE Phosphatidate cytidylyltransferase ECTO73_03758 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ECTO73_03759 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) ECTO73_03765 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ECTO73_03768 ENOG4105DIN metallophosphoesterase ECTO73_03770 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR ECTO73_03771 ENOG4105C0H protease ECTO73_03774 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) ECTO73_03775 ENOG4105EN6 Membrane ECTO73_03779 ENOG4105S6R Iron-hydroxamate transporter permease subunit ECTO73_03780 ENOG4105J76 Periplasmic binding protein ECTO73_03781 ENOG4105E0A ABC, transporter ECTO73_03782 ENOG4105E0K tonB-dependent siderophore receptor ECTO73_03783 ENOG4105BZ4 penicillin-binding protein ECTO73_03784 ENOG4105CQ7 ATP-dependent helicase ECTO73_03785 ENOG4107XID 2'-5' rna ligase ECTO73_03787 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters ECTO73_03789 ENOG4105DJ0 Poly(A) Polymerase ECTO73_03790 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ECTO73_03792 ENOG4108VEV chaperone ECTO73_03793 ENOG4105CW0 outer membrane usher protein ECTO73_03794 ENOG4108XEY fimbrial-like adhesin protein ECTO73_03795 ENOG4105SYG Fimbrial protein ECTO73_03796 ENOG4105SN2 fimbrial-like adhesin protein ECTO73_03797 ENOG4105P0Q fimbrial-like protein YadC ECTO73_03800 ENOG4108A32 Transposase ECTO73_03802 ENOG4107BJW polysaccharide deacetylase ECTO73_03803 ENOG4108YTN IIa component ECTO73_03804 ENOG4105E3A (ABC) transporter ECTO73_03805 ENOG4105DA5 (ABC) transporter ECTO73_03806 ENOG41077A9 carbonic anhydrase ECTO73_03807 ENOG4108UGV hypoxanthine phosphoribosyltransferase ECTO73_03808 ENOG4105DZG Dehydrogenase ECTO73_03809 ENOG4105E3B Multicopper oxidase ECTO73_03810 ENOG4108ZRK uncharacterized protein yacC ECTO73_03814 ENOG4107QIJ Aconitate hydratase 2 ECTO73_03815 ENOG4108NST exported protein ECTO73_03816 ENOG4107QN2 dihydrolipoyl dehydrogenase ECTO73_03817 ENOG4107QSN dihydrolipoamide acetyltransferase ECTO73_03818 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) ECTO73_03820 ENOG41073TP transcriptional regulator ECTO73_03821 ENOG4105C85 amino acid ECTO73_03822 ENOG4106A72 regulatory protein AmpE ECTO73_03823 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ECTO73_03824 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase ECTO73_03825 ENOG4108ZUW Major pilin subunit ECTO73_03826 ENOG4107QHF type ii secretion system protein e ECTO73_03827 ENOG4105D7Q type ii secretion system ECTO73_03829 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ECTO73_03832 ENOG4105M6F mutator MutT protein ECTO73_03837 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ECTO73_03838 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ECTO73_03839 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) ECTO73_03840 ENOG4105CPF Cell wall formation (By similarity) ECTO73_03843 ENOG4105CNI cell division protein FtsW ECTO73_03844 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) ECTO73_03846 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) ECTO73_03847 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ECTO73_03848 ENOG4105CJN penicillin-binding protein ECTO73_03849 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) ECTO73_03852 ENOG4107B7Y DNA-binding transcriptional regulator FruR ECTO73_03853 ENOG4108ZP8 Acetolactate synthase small subunit ECTO73_03854 ENOG4105C7K acetolactate synthase ECTO73_03855 ENOG41064T2 transcriptional regulator, lysR family ECTO73_03856 ENOG41064T2 transcriptional regulator, lysR family ECTO73_03859 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ECTO73_03862 ENOG4105S8Q sugar efflux transporter ECTO73_03867 ENOG4105DP9 ABC transporter ECTO73_03868 ENOG4106SMU thiamine transporter membrane protein ECTO73_03870 ENOG4108KF1 Membrane ECTO73_03871 ENOG41063TF transcriptional regulator (AraC ECTO73_03874 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase ECTO73_03875 ENOG4105CQ2 DNA polymerase ECTO73_03877 ENOG4105D3G Pseudouridine synthase ECTO73_03878 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) ECTO73_03880 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ECTO73_03885 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) ECTO73_03887 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF ECTO73_03888 ENOG4105C54 Major Facilitator superfamily ECTO73_03889 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein ECTO73_03890 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase ECTO73_03897 ENOG4106YT9 Enoyl-CoA hydratase ECTO73_03899 ENOG4108XNW Transcriptional activatory protein CaiF ECTO73_03900 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain ECTO73_03901 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ECTO73_03905 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase ECTO73_03907 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ECTO73_03908 ENOG4105DTN riboflavin biosynthesis protein ribF ECTO73_03912 ENOG41063Z6 transcriptional regulator, lysR family ECTO73_03915 ENOG4105WI6 cell killing protein encoded within cryptic prophage ECTO73_03916 ENOG4108SER Transposase ECTO73_03922 ENOG4108QUJ UPF0174 protein YaaW ECTO73_03923 ENOG4106HK8 GPR1 FUN34 yaaH family protein ECTO73_03924 ENOG4108RIR Molybdenum cofactor biosynthesis protein ECTO73_03926 ENOG4105BZG amino acid carrier protein ECTO73_03928 ENOG41062C6 Protein of unknown function (DUF2502) ECTO73_03929 ENOG4105D98 threonine synthase ECTO73_03931 ENOG4105CFH Aspartokinase ECTO73_03933 ENOG4106FVC RNA methyltransferase ECTO73_03934 ENOG41065U4 response regulator ECTO73_03935 ENOG4105CT7 inner membrane cred family protein ECTO73_03936 ENOG4105EB3 Histidine kinase ECTO73_03937 ENOG4105E3W Two component transcriptional regulator (Winged helix family ECTO73_03938 ENOG4108RH0 Crea protein ECTO73_03939 ENOG4105UEI Transcriptional Regulator AraC Family ECTO73_03943 ENOG4107SC1 transglycosylase ECTO73_03944 ENOG4105C5H ABC transporter ECTO73_03945 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase ECTO73_03946 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ECTO73_03947 ENOG4105EAC phosphoserine phosphatase ECTO73_03948 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) ECTO73_03955 ENOG4105G0K glycine radical enzyme YjjI family ECTO73_03956 ENOG41076CZ activating enzyme ECTO73_03957 ENOG4105EYA deoxyribonuclease ECTO73_03958 ENOG4108NRW Phospholipase, patatin family ECTO73_03960 ENOG4105K3G Periplasmic Protein ECTO73_03962 ENOG4105PAD Hydrolase ECTO73_03963 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ECTO73_03964 ENOG4108WPU DNA polymerase III subunit psi ECTO73_03965 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) ECTO73_03969 ENOG4105YBH Protein of unknown function (DUF1435) ECTO73_03970 ENOG4108819 ferric iron reductase ECTO73_03971 ENOG4108T94 DNA-binding transcriptional activator BglJ ECTO73_03972 ENOG4108N8T regulatoR ECTO73_03973 ENOG4105DWK Membrane ECTO73_03976 ENOG4106CVF DNA replication protein ECTO73_03977 ENOG4105RI1 glycoprotein receptor ECTO73_03979 ENOG4105CPQ Dehydrogenase ECTO73_03980 ENOG410617M Transcriptional regulator ECTO73_03981 ENOG4108I5G Major Facilitator superfamily ECTO73_03982 ENOG4105C8Q Methyl-accepting chemotaxis ECTO73_03983 ENOG4105D22 carbon starvation protein ECTO73_03984 ENOG4105VCD cytoplasmic protein ECTO73_03985 ENOG4105CKI cobalamin synthesis protein ECTO73_03990 ENOG41083G8 Multidrug resistance protein MdtM ECTO73_03991 ENOG4106BRA Membrane ECTO73_03992 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase ECTO73_03993 ENOG4105CIZ coA-substrate-specific enzyme activase ECTO73_03996 ENOG4105CBP Major Facilitator ECTO73_03998 ENOG41074DU domain protein ECTO73_03999 ENOG4108P2H Inner membrane protein YjiG ECTO73_04000 ENOG4105DYB Isoaspartyl dipeptidase ECTO73_04001 ENOG4107YNJ LysR family Transcriptional regulator ECTO73_04004 ENOG4105C6F GntR Family Transcriptional Regulator ECTO73_04006 ENOG4105DEI Mannitol dehydrogenase ECTO73_04008 ENOG4107EFN gluconate transport system permease 3 ECTO73_04009 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin ECTO73_04010 ENOG4108T65 Fimbrial ECTO73_04011 ENOG4108SQA Fimbrial ECTO73_04012 ENOG4105CW0 outer membrane usher protein ECTO73_04013 ENOG4108NAE Fimbrial chaperone protein ECTO73_04014 ENOG4108S54 Fimbrial protein ECTO73_04016 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off ECTO73_04017 ENOG4108W9T type 1 fimbriae regulatory protein ECTO73_04020 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria ECTO73_04021 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) ECTO73_04027 ENOG41080VW acetyltransferase ECTO73_04028 ENOG4105DTA methyltransferase ECTO73_04030 ENOG4105CN9 Peptidase m42 family protein ECTO73_04031 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) ECTO73_04032 ENOG4105DT3 PTS system, galactitol-specific IIc component ECTO73_04033 ENOG4106P19 photosystem i assembly btpa ECTO73_04034 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) ECTO73_04035 ENOG4108RK0 3-epimerase ECTO73_04036 ENOG4108PQ7 sgc region transcriptional regulator ECTO73_04037 ENOG4106P37 HTH-type transcriptional regulator YjhI ECTO73_04038 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ECTO73_04039 ENOG4105C01 Dihydroxy-acid dehydratase ECTO73_04040 ENOG4105C6Z Gluconate ECTO73_04041 ENOG4105DKT Transcriptional regulator ECTO73_04043 ENOG4107W7X Aldolase ECTO73_04045 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) ECTO73_04046 ENOG4108SHN Glycosyl transferase, family 2 ECTO73_04047 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 ECTO73_04052 ENOG4105F5W AtP-binding protein ECTO73_04053 ENOG4105D70 Integrase catalytic subunit ECTO73_04060 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles ECTO73_04062 ENOG4106WJE Protein of unknown function (DUF987) ECTO73_04063 ENOG4108YGG dna repair protein ECTO73_04064 ENOG4105MFG Antirestriction protein ECTO73_04065 ENOG4106H6R UPF0380 protein ECTO73_04067 ENOG4105F4K antigen 43 ECTO73_04075 ENOG4105KF5 hemolysin expression-modulating protein ECTO73_04082 ENOG4108YXQ IS66 Orf2 family protein ECTO73_04083 ENOG4105E5H Transposase ECTO73_04086 ENOG4108SF5 RNA Polymerase ECTO73_04087 ENOG4108S3W Anti-feci sigma factor, fecr ECTO73_04088 ENOG4105GAV receptor ECTO73_04089 ENOG4108HUF Transporter ECTO73_04090 ENOG4105DQ5 transport system permease protein ECTO73_04091 ENOG4108IHU transport system permease protein ECTO73_04092 ENOG4105E0A ABC, transporter ECTO73_04098 ENOG4105C94 Transporter ECTO73_04105 ENOG4107RJ5 oxidoreductase ECTO73_04106 ENOG4105JHE Major Facilitator Superfamily ECTO73_04107 ENOG4105VNT transposase (IS4 family) protein ECTO73_04110 ENOG4108I6E Sulfatase ECTO73_04115 ENOG4105DQ4 alcohol dehydrogenase ECTO73_04116 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family ECTO73_04117 ENOG4105CPQ Dehydrogenase ECTO73_04118 ENOG4105CHR reductase ECTO73_04119 ENOG4105C6Z Gluconate ECTO73_04120 ENOG4105K2J Transcriptional regulator ECTO73_04121 ENOG4105D7A ATP-binding protein ECTO73_04122 ENOG4108K5H permease YjgP YjgQ family protein ECTO73_04123 ENOG4108M8S permease YjgP YjgQ family protein ECTO73_04125 ENOG4105MYG DNA polymerase iii, chi subunit ECTO73_04126 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) ECTO73_04127 ENOG4108M3P Membrane ECTO73_04128 ENOG4108M3P Membrane ECTO73_04129 ENOG4108MJ3 acetyltransferase ECTO73_04130 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) ECTO73_04131 ENOG4105DBV ornithine carbamoyltransferase ECTO73_04133 ENOG4105XEP YhcH YjgK YiaL family protein ECTO73_04134 ENOG4108XFH Transcriptional regulator ECTO73_04135 ENOG4105F6U Short-chain dehydrogenase reductase Sdr ECTO73_04136 ENOG4108UQ8 endoribonuclease L-psp ECTO73_04139 ENOG4105KME endoribonuclease L-psp ECTO73_04140 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic ECTO73_04142 ENOG4105D4X repressor ECTO73_04143 ENOG4105C5Y PTS System ECTO73_04144 ENOG4105CG3 alpha amylase, catalytic region ECTO73_04145 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase ECTO73_04146 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) ECTO73_04148 ENOG4105CMS peptidase U62, modulator of DNA gyrase ECTO73_04150 ENOG4105DFU Cell wall formation (By similarity) ECTO73_04152 ENOG41062B0 ABC transporter, permease ECTO73_04153 ENOG4107R9N ABC transporter ECTO73_04154 ENOG4105C2J ABC transporter ECTO73_04155 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator ECTO73_04156 ENOG4105F0N pyrophosphate phospho-hydrolase ECTO73_04157 ENOG4108ZHD aig2 family ECTO73_04158 ENOG4105MA0 exported protein ECTO73_04159 ENOG4105CFU surface antigen ECTO73_04162 ENOG4105C37 (CBS) domain ECTO73_04163 ENOG41061GZ Protein of unknown function (DUF1107) ECTO73_04164 ENOG4108UUE Transcriptional regulator ECTO73_04165 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase ECTO73_04166 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic ECTO73_04167 ENOG4105KVH Transcriptional regulator ECTO73_04168 ENOG4105ECR NmrA family ECTO73_04169 ENOG4105DXC membrane ECTO73_04171 ENOG4105C85 amino acid ECTO73_04172 ENOG4108V1T peptidylprolyl cis-trans isomerase ECTO73_04173 ENOG4105FHY Opacity-associated protein A ECTO73_04175 ENOG4105CHR reductase ECTO73_04177 ENOG4105E39 Enoyl-CoA hydratase ECTO73_04178 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) ECTO73_04179 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) ECTO73_04180 ENOG4107S3R L-aspartate oxidase ECTO73_04181 ENOG41069H7 transport system small permease component ECTO73_04182 ENOG4105CG6 trap dicarboxylate transporter dctm subunit ECTO73_04183 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit ECTO73_04185 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) ECTO73_04188 ENOG4105KIT UPF0379 protein yjfY ECTO73_04193 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport ECTO73_04194 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC ECTO73_04197 ENOG4108MXZ Esterase ECTO73_04198 ENOG4105WSB biofilm stress and motility protein A ECTO73_04199 ENOG4105S17 UPF0379 protein yjfN ECTO73_04200 ENOG4105CSU acyl-Coa dehydrogenase ECTO73_04201 ENOG4106032 Glutathionylspermidine synthase ECTO73_04202 ENOG4108KXT Conserved Protein ECTO73_04203 ENOG4105Z6B inner membrane protein yjfl ECTO73_04204 ENOG4107VNS Protein of unknown function (DUF2491) ECTO73_04206 ENOG4108ZSJ is1 orf2 ECTO73_04207 ENOG4107VNS Protein of unknown function (DUF2491) ECTO73_04208 ENOG4108P9J Phage shock protein A ECTO73_04209 ENOG4105FUX Conserved Protein ECTO73_04210 ENOG4105C2N RNA methyltransferase TrmH family group 3 ECTO73_04211 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ECTO73_04215 ENOG4105EPW hflc protein ECTO73_04216 ENOG4107QJR hflk protein ECTO73_04217 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ECTO73_04218 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ECTO73_04221 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ECTO73_04222 ENOG4105K8N protein family UPF0079, ATPase ECTO73_04223 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ECTO73_04224 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ECTO73_04231 ENOG4105EGS Mechanosensitive ion channel ECTO73_04232 ENOG4106CG8 Inner membrane protein YjeO ECTO73_04233 ENOG4106V5W ECTO73_04234 ENOG4107SC7 Inner membrane transporter yjeM ECTO73_04236 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) ECTO73_04237 ENOG4105E33 succinate dehydrogenase ECTO73_04240 ENOG41066YJ Beta-lactamase ECTO73_04241 ENOG4105QNF Outer membrane lipoprotein ECTO73_04242 ENOG4105KPY Small multidrug resistance protein ECTO73_04244 ENOG4106BSU Entericidin B ECTO73_04245 ENOG4106HKS Entericidin EcnA/B family ECTO73_04247 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ECTO73_04248 ENOG4105MTB Uncharacterized protein YjeJ ECTO73_04249 ENOG4108ZVF (LipO)protein ECTO73_04252 ENOG4105DVH amino acid ECTO73_04253 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 ECTO73_04254 ENOG4108IJ0 Aspartate ammonia-lyase ECTO73_04255 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter ECTO73_04257 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) ECTO73_04258 ENOG4108SIC Transcriptional regulator ECTO73_04260 ENOG4108M3R transcriptional activator CadC ECTO73_04261 ENOG4105D5Q Arginine ornithine antiporter ECTO73_04262 ENOG4105CXN decarboxylase ECTO73_04263 ENOG4105DUX Transporter ECTO73_04264 ENOG4105CRK lysyL-tRNA synthetase ECTO73_04267 ENOG410830R acetyltransferase ECTO73_04268 ENOG4105VR1 Pfam:DUF1271 ECTO73_04269 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ECTO73_04270 ENOG4108MRH transcriptional regulatory protein ECTO73_04271 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter ECTO73_04272 ENOG4107GFK fumarate ECTO73_04273 ENOG4108R5S membrane ECTO73_04274 ENOG4105CT4 transporter ECTO73_04275 ENOG4105F8D glycoside hydrolase family 4 ECTO73_04276 ENOG4108K2B transcriptional regulator ECTO73_04277 ENOG4105CXN decarboxylase ECTO73_04278 ENOG4106ZGR Transcriptional regulator ECTO73_04279 ENOG4105D5Q Arginine ornithine antiporter ECTO73_04280 ENOG4105DIJ Phosphoethanolamine transferase ECTO73_04281 ENOG4105XJC Two component transcriptional regulator (Winged helix family ECTO73_04282 ENOG4105ECM Sensor protein basS pmrB ECTO73_04285 ENOG4105CSH Transporter ECTO73_04286 ENOG4108YIV ECTO73_04287 ENOG4108F5E vimentin ECTO73_04288 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ECTO73_04289 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase ECTO73_04290 ENOG4105D5T phosphonate abc transporter ECTO73_04291 ENOG4105EHI Phosphonate ABC transporter, periplasmic ECTO73_04293 ENOG4107RJJ Transcriptional regulator ECTO73_04294 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG ECTO73_04295 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH ECTO73_04296 ENOG4105EKV Phosphonate metabolism protein ECTO73_04297 ENOG4105FT8 Phosphonate metabolism ECTO73_04298 ENOG4105ENV phosphonate C-P lyase system protein PhnK ECTO73_04299 ENOG4105HRV phosphonate c-p lyase system protein phnl ECTO73_04300 ENOG4105FD8 phosphonate metabolism protein PhnM ECTO73_04301 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) ECTO73_04302 ENOG410849A acetyltransferase, (GNAT) family ECTO73_04303 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein ECTO73_04304 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 ECTO73_04305 ENOG4108YZG isomerase ECTO73_04306 ENOG4105NYY transcriptional regulator, RpiR ECTO73_04307 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ECTO73_04308 ENOG4105C2J ABC transporter ECTO73_04309 ENOG4105CNN ABC, transporter ECTO73_04310 ENOG4105UP7 3-epimerase ECTO73_04311 ENOG4107TFG D-allose kinase ECTO73_04312 ENOG4105EUZ Beta-lactamase domain protein ECTO73_04313 ENOG4106833 ECTO73_04314 ENOG4105J12 Multidrug resistance protein mdtN ECTO73_04315 ENOG4108MI0 Resistance protein ECTO73_04316 ENOG4105ETP RND efflux system, outer membrane lipoprotein ECTO73_04317 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_04319 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_04320 ENOG41082ND Uncharacterized protein yjcO ECTO73_04321 ENOG4105CK2 sodium dicarboxylate symporter ECTO73_04322 ENOG4108W0S formate-dependent nitrite reductase complex ECTO73_04324 ENOG4108QKW cytochrome c-type biogenesis protein ECTO73_04325 ENOG4105DVI reductase, NrfD ECTO73_04326 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ECTO73_04327 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit ECTO73_04329 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ECTO73_04330 ENOG41062QD Membrane ECTO73_04333 ENOG4105EEQ Na H antiporter ECTO73_04334 ENOG4105C7N Xanthine uracil vitamin C permease ECTO73_04336 ENOG4108Z4X TRANSCRIPTIONal ECTO73_04337 ENOG4108W3Q Transcriptional regulator ECTO73_04339 ENOG4108M8H domain protein ECTO73_04340 ENOG4105PMV Membrane ECTO73_04341 ENOG4108UUM single-stranded DNA-binding protein ECTO73_04342 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ECTO73_04343 ENOG4105MSB protein, conserved in bacteria ECTO73_04344 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme ECTO73_04345 ENOG4105F0S class B acid phosphatase ECTO73_04347 ENOG4105CGF Aromatic amino acid aminotransferase ECTO73_04348 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ECTO73_04349 ENOG4105CDU Replicative dna helicase ECTO73_04350 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein ECTO73_04351 ENOG4105P4Z Phage shock protein G ECTO73_04352 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ECTO73_04355 ENOG4105MYN Zinc uptake regulation protein ECTO73_04356 ENOG4105VDW Csbd family ECTO73_04357 ENOG4107R73 Mate efflux family protein ECTO73_04359 ENOG41080IJ Diacylglycerol kinase ECTO73_04366 ENOG4107W52 maltose operon periplasmic protein ECTO73_04368 ENOG4108IJ9 (ABC) transporter ECTO73_04370 ENOG4107FKK extracellular solute-binding protein family 1 ECTO73_04371 ENOG4105D56 permease protein ECTO73_04372 ENOG4105EG2 ABC transporter, permease ECTO73_04373 ENOG4107QNK )-transporter ECTO73_04375 ENOG4105E3R (LipO)protein ECTO73_04376 ENOG4108Q9C Periplasmic Protein ECTO73_04377 ENOG4108MDC (LipO)protein ECTO73_04382 ENOG4105CFH Aspartokinase ECTO73_04383 ENOG4108ZR5 Conserved Protein ECTO73_04384 ENOG4105FE9 pseudouridine synthase ECTO73_04386 ENOG4105EAM Na Pi-cotransporter ECTO73_04387 ENOG4105C3R Methionine synthase ECTO73_04388 ENOG41069M3 Transcriptional regulator ECTO73_04391 ENOG4108I9X Isocitrate lyase ECTO73_04392 ENOG4107QP3 malate synthase g ECTO73_04393 ENOG4105CVG Homoserine O-transsuccinylase ECTO73_04394 ENOG4105K5X acetyltransferase ECTO73_04395 ENOG41062WK cellular response to acidity ECTO73_04402 ENOG4105C12 Phosphoribosylglycinamide synthetase ECTO73_04403 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ECTO73_04404 ENOG4105BZU Histidine kinase ECTO73_04406 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism ECTO73_04407 ENOG4108T8B Protein of unknown function (DUF1481) ECTO73_04408 ENOG4105K70 DNA-binding protein ECTO73_04409 ENOG4105R2J Conserved Protein ECTO73_04417 ENOG4105D06 uba thif-type nad fad binding protein ECTO73_04418 ENOG4105WHD thiamine biosynthesis protein ThiS ECTO73_04420 ENOG4105D41 biosynthesis protein thiH ECTO73_04422 ENOG410645W Thiamin biosynthesis protein ThiH ECTO73_04430 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ECTO73_04431 ENOG4105PM1 preprotein translocase subunit SecE ECTO73_04438 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase ECTO73_04439 ENOG4105D4A Cell wall formation (By similarity) ECTO73_04446 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) ECTO73_04449 ENOG4108Y73 Membrane ECTO73_04450 ENOG4105EJ2 Transcriptional regulator ECTO73_04452 ENOG4105C5Q Transcriptional regulator ECTO73_04455 ENOG4105CAS nag kinase ECTO73_04456 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase ECTO73_04459 ENOG4105DIJ Phosphoethanolamine transferase ECTO73_04460 ENOG4106R3P AraC family transcriptional regulator ECTO73_04461 ENOG4108XCZ PTS System ECTO73_04462 ENOG4108AHH pyruvate formate lyase II activase ECTO73_04463 ENOG4105C6N Formate acetyltransferase ECTO73_04464 ENOG4108YRF PTS System ECTO73_04465 ENOG4105DM4 PTS System ECTO73_04466 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ECTO73_04467 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ECTO73_04468 ENOG4105DCT glycerol dehydrogenase ECTO73_04469 ENOG4108XC3 NADH ubiquinone oxidoreductase ECTO73_04470 ENOG4108Q5Y Membrane ECTO73_04471 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) ECTO73_04472 ENOG4105SYT Methylenetetrahydrofolate reductase ECTO73_04473 ENOG4105CFH Aspartokinase ECTO73_04474 ENOG4105C28 cystathionine ECTO73_04476 ENOG4107S01 Repressor protein MetJ ECTO73_04478 ENOG4105C25 Primosomal protein n' ECTO73_04479 ENOG4105ETE Transcriptional regulator (LacI family ECTO73_04480 ENOG41063M6 Cell Division Protein ECTO73_04482 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) ECTO73_04483 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ECTO73_04486 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ECTO73_04488 ENOG4105CBT Fructose-1,6-bisphosphatase ECTO73_04489 ENOG4105DP0 ferredoxin-NADP reductase ECTO73_04491 ENOG41065TG regulatoR ECTO73_04492 ENOG4108VTS Membrane ECTO73_04493 ENOG4105EBK exported protein ECTO73_04496 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ECTO73_04499 ENOG4105FMW periplasmic ECTO73_04500 ENOG4105E3W Two component transcriptional regulator (Winged helix family ECTO73_04501 ENOG4105E0F Histidine kinase ECTO73_04502 ENOG4108RPX mosc domain containing protein ECTO73_04504 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ECTO73_04512 ENOG41064BA PTS system, fructose-specific, IIA component ECTO73_04513 ENOG4105DM4 PTS System ECTO73_04514 ENOG4105CN9 Peptidase m42 family protein ECTO73_04515 ENOG4106C3V frv operon regulatory protein ECTO73_04516 ENOG4108V87 frv operon regulatory protein ECTO73_04518 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_04520 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ECTO73_04521 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ECTO73_04522 ENOG4108MG3 formate dehydrogenase ECTO73_04525 ENOG41068KX affects formate dehydrogenase-N ECTO73_04526 ENOG4106UEE Transcriptional regulator ECTO73_04528 ENOG4105SUU thioesterase domain ECTO73_04531 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 ECTO73_04532 ENOG4105E98 transcriptional regulator DeoR family ECTO73_04533 ENOG4108MGF sugar kinase ECTO73_04534 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ECTO73_04535 ENOG4105D2M Aldolase ECTO73_04536 ENOG4107QKS N-acylglucosamine 2-epimerase ECTO73_04537 ENOG4107WI4 Aldose-1-epimerase ECTO73_04538 ENOG4105CJQ hydrolase, family 31 ECTO73_04539 ENOG4105CT4 transporter ECTO73_04540 ENOG4105CT4 transporter ECTO73_04541 ENOG4105CT4 transporter ECTO73_04542 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is ECTO73_04543 ENOG4105R9B Major Facilitator ECTO73_04544 ENOG4108KHF Resistance protein ECTO73_04545 ENOG4108K85 Transcriptional regulator ECTO73_04548 ENOG4105C5F glutamine synthetase ECTO73_04549 ENOG4105CUX Signal transduction histidine kinase ECTO73_04550 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ECTO73_04551 ENOG4106FIY ECTO73_04552 ENOG4105D4P Coproporphyrinogen iii oxidase ECTO73_04558 ENOG4105C2M dna polymerase I ECTO73_04560 ENOG4106HNH Acyl-transferase ECTO73_04562 ENOG4108Z33 Thiol disulfide Interchange Protein ECTO73_04563 ENOG4105E27 serine threonine protein kinase ECTO73_04564 ENOG4105PC1 Conserved Protein ECTO73_04565 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) ECTO73_04566 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b ECTO73_04567 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b ECTO73_04574 ENOG4108RR8 protoporphyrinogen oxidase ECTO73_04575 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) ECTO73_04576 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein ECTO73_04579 ENOG4105CHU acetyl-coa acetyltransferase ECTO73_04580 ENOG4107QK7 reductase ECTO73_04581 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) ECTO73_04582 ENOG4105MDZ Transcriptional activator rfaH ECTO73_04583 ENOG4105F8V Hydrolase, tatD family ECTO73_04584 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ECTO73_04585 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) ECTO73_04586 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) ECTO73_04588 ENOG4105JC1 sterol-binding domain protein ECTO73_04590 ENOG4105CGY Dna recombination protein ECTO73_04591 ENOG4108I5U Uridine phosphorylase ECTO73_04592 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) ECTO73_04593 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ECTO73_04594 ENOG4105DZ2 Transcriptional regulator ECTO73_04595 ENOG4105EMK carboxylate amino acid amine transporter ECTO73_04596 ENOG4105DQF Hydrolase ECTO73_04597 ENOG4108EUD Lysophospholipase ECTO73_04600 ENOG4105C9U ATP-dependent DNA helicase RecQ ECTO73_04601 ENOG4105HDD phospholipase ECTO73_04602 ENOG4108VUY thioesterase Superfamily protein ECTO73_04603 ENOG4105FR1 rard protein ECTO73_04604 ENOG4106WR8 Inner membrane protein YigG ECTO73_04605 ENOG4105NRM Membrane ECTO73_04606 ENOG4107QUT magnesium and cobalt transport protein CorA ECTO73_04607 ENOG4108T58 Mg2 transport protein CorA ECTO73_04608 ENOG4105C4R Atp-dependent dna helicase ECTO73_04609 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant ECTO73_04611 ENOG4105CT0 Protein of unknown function, DUF484 ECTO73_04613 ENOG4105S7Z (LipO)protein ECTO73_04615 ENOG4107T0K Adenylate cyclase ECTO73_04617 ENOG41076E6 Uroporphyrinogen-III Synthase ECTO73_04618 ENOG4105ECF c-methyltransferase ECTO73_04619 ENOG410601J HemY protein ECTO73_04622 ENOG4105ENH Sulfatase ECTO73_04623 ENOG4105C4X radical SAM domain protein ECTO73_04628 ENOG4105C85 amino acid ECTO73_04631 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) ECTO73_04632 ENOG4105EGZ biosynthesis protein ECTO73_04633 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ECTO73_04634 ENOG4108WJ1 acetyltransferase ECTO73_04635 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) ECTO73_04636 ENOG4105C1B dTDP-glucose 4-6-dehydratase ECTO73_04637 ENOG4108IJ1 Dehydrogenase ECTO73_04638 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ECTO73_04639 ENOG4105SFE lipopolysaccharide biosynthesis protein ECTO73_04640 ENOG4105ESV Glycosyl transferase, family 4 ECTO73_04643 ENOG4105K63 Thioredoxin ECTO73_04645 ENOG4105C9X ppx gppa phosphatase ECTO73_04646 ENOG4105C4R Atp-dependent dna helicase ECTO73_04648 ENOG4105KQ5 peptidylprolyl cis-trans isomerase ECTO73_04650 ENOG4105EMY transcriptional regulator ECTO73_04651 ENOG4105C7B Threonine dehydratase ECTO73_04653 ENOG4105CM2 brancheD-chain amino acid aminotransferase ECTO73_04654 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit ECTO73_04656 ENOG4105C0P Mg chelatase subunit ChlI ECTO73_04657 ENOG4108WFC UPF0438 protein yifE ECTO73_04666 ENOG4107EJG GntR family transcriptional regulator ECTO73_04667 ENOG4105C0R drug resistance transporter emrb qaca subfamily ECTO73_04668 ENOG4105ETE Transcriptional regulator (LacI family ECTO73_04669 ENOG4108RVA ribokinase ECTO73_04670 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ECTO73_04671 ENOG4105CNN ABC, transporter ECTO73_04672 ENOG4105C2J ABC transporter ECTO73_04673 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) ECTO73_04676 ENOG4105EV2 VWA domain protein interacting with AAA ATPase ECTO73_04678 ENOG4108VVK transcriptional Regulator, AsnC ECTO73_04679 ENOG4105QTB Flavodoxin ECTO73_04682 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation ECTO73_04684 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) ECTO73_04693 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ECTO73_04694 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) ECTO73_04695 ENOG4105C8U phosphate abc transporter ECTO73_04696 ENOG4105E2Z phosphate ABC transporter (Permease ECTO73_04697 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ECTO73_04698 ENOG4108UTW Plays a role in the regulation of phosphate uptake ECTO73_04699 ENOG4105CID antiterminator ECTO73_04700 ENOG4105C5Y PTS System ECTO73_04701 ENOG4105CS2 ec 3.2.1.21 ECTO73_04702 ENOG4108P68 Outer membrane porin ECTO73_04703 ENOG4105DYC esterase ECTO73_04704 ENOG4107VKM 6-phosphogluconolactonase ECTO73_04705 ENOG4106611 bacteriocin immunity ECTO73_04707 ENOG4108YXQ IS66 Orf2 family protein ECTO73_04708 ENOG4105E5H Transposase ECTO73_04709 ENOG4106HGK Inner membrane protein yieI ECTO73_04710 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 ECTO73_04711 ENOG4105C7N Xanthine uracil vitamin C permease ECTO73_04712 ENOG4108YYH Nadph-dependent fmn reductase ECTO73_04713 ENOG4105E8Q phosphopantetheinyl transferase ECTO73_04716 ENOG4108P6C Tryptophan transporter of low affinity ECTO73_04725 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ECTO73_04731 ENOG4108MVM Transposase ECTO73_04732 ENOG41090WB Transposase is3 is911 ECTO73_04734 ENOG4108ZQS transposase ECTO73_04735 ENOG4105QYK bacteriophage lambda Bor protein homolog ECTO73_04741 ENOG4105E93 esterase ECTO73_04742 ENOG4105NIV Esterase ECTO73_04743 ENOG4107RNH Outer membrane receptor FepA ECTO73_04748 ENOG4108MBX Secretion Protein ECTO73_04753 ENOG4105H3G oxidoreductase ECTO73_04755 ENOG4108YXQ IS66 Orf2 family protein ECTO73_04759 ENOG4105VUN Transcriptional regulator ECTO73_04765 ENOG4108R0M Aminoglycoside ECTO73_04769 ENOG4105BZU Histidine kinase ECTO73_04775 ENOG4108VSE mercuric transport protein ECTO73_04776 ENOG4105W1Y Transcriptional regulator ECTO73_04782 ENOG4106CQM replication ECTO73_04788 ENOG4107CBI conjugal transfer fertility inhibition protein ECTO73_04789 ENOG4107U2T alpha beta ECTO73_04792 ENOG4105VGJ Virulence-associated protein ECTO73_04793 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A ECTO73_04806 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB ECTO73_04807 ENOG4105EZN Cobyrinic acid ac-diamide synthase ECTO73_04811 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) ECTO73_04812 ENOG4105DUU IucA IucC family protein ECTO73_04816 ENOG41082CG Protein CrcB homolog ECTO73_04818 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) ECTO73_04819 ENOG4105CC5 ABC transporter ECTO73_04820 ENOG4105CC5 ABC transporter ECTO73_04821 ENOG4105DIK (ABC) transporter ECTO73_04828 ENOG4106JVB Replication Protein ECTO73_04833 ENOG4108NC2 Outer membrane protease ECTO73_04834 ENOG4105MP0 transposase ECTO73_04835 ENOG4105D4K integrase catalytic ECTO73_04838 ENOG4105DJY efflux transporter, rnd family, mfp subunit ECTO73_04840 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ECTO73_04847 ENOG4105CKI cobalamin synthesis protein ECTO73_04849 ENOG4105K4U addiction module toxin, RelE StbE family ECTO73_04856 ENOG4107QJE Chromosome Partitioning Protein ECTO73_04866 ENOG4108X73 DNA- binding protein