locus-tag class description FIU16_00015 ENOG4108BMY protease FIU16_00020 ENOG4108BMY protease FIU16_00035 ENOG4105MP0 transposase FIU16_00055 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FIU16_00080 ENOG4108YXQ IS66 Orf2 family protein FIU16_00095 ENOG4108BMY protease FIU16_00155 ENOG4107CBI conjugal transfer fertility inhibition protein FIU16_00165 ENOG4108YXQ IS66 Orf2 family protein FIU16_00175 ENOG4105E5H Transposase FIU16_00180 ENOG4108YXQ IS66 Orf2 family protein FIU16_00185 ENOG4108ZQS transposase FIU16_00200 ENOG4105F2I Transposase FIU16_00205 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) FIU16_00260 ENOG4106JVB Replication Protein FIU16_00275 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FIU16_00285 ENOG4105XY2 plasmid maintenance protein CcdA FIU16_00290 ENOG4105PPN plasmid maintenance protein, CcdB FIU16_00340 ENOG4108C33 Resolvase FIU16_00345 ENOG4106JQ7 FIU16_00400 ENOG4108YXQ IS66 Orf2 family protein FIU16_00405 ENOG4105E5H Transposase FIU16_00420 ENOG4105IYK transposase FIU16_00435 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) FIU16_00440 ENOG4105F2I Transposase FIU16_00490 ENOG4105EKQ RNA-directed DNA polymerase FIU16_00495 ENOG4108SER Transposase FIU16_00520 ENOG4105F2I Transposase FIU16_00535 ENOG4105CQ2 DNA polymerase FIU16_00540 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FIU16_00555 ENOG41063TF transcriptional regulator (AraC FIU16_00560 ENOG4108KF1 Membrane FIU16_00570 ENOG4106SMU thiamine transporter membrane protein FIU16_00575 ENOG4105DP9 ABC transporter FIU16_00590 ENOG4105S8Q sugar efflux transporter FIU16_00605 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FIU16_00620 ENOG41064T2 transcriptional regulator, lysR family FIU16_00625 ENOG4105C7K acetolactate synthase FIU16_00630 ENOG4108ZP8 Acetolactate synthase small subunit FIU16_00640 ENOG4107B7Y DNA-binding transcriptional regulator FruR FIU16_00655 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FIU16_00660 ENOG4105CJN penicillin-binding protein FIU16_00665 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FIU16_00670 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FIU16_00685 ENOG4105CNI cell division protein FtsW FIU16_00700 ENOG4105CPF Cell wall formation (By similarity) FIU16_00705 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FIU16_00710 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FIU16_00715 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FIU16_00735 ENOG4105M6F mutator MutT protein FIU16_00750 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FIU16_00760 ENOG4105D7Q type ii secretion system FIU16_00765 ENOG4107QHF type ii secretion system protein e FIU16_00770 ENOG4108ZUW Major pilin subunit FIU16_00775 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FIU16_00780 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FIU16_00785 ENOG4106A72 regulatory protein AmpE FIU16_00790 ENOG4105C85 amino acid FIU16_00795 ENOG41073TP transcriptional regulator FIU16_00800 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FIU16_00805 ENOG4107QSN dihydrolipoamide acetyltransferase FIU16_00810 ENOG4107QN2 dihydrolipoyl dehydrogenase FIU16_00815 ENOG4108NST exported protein FIU16_00820 ENOG4107QIJ Aconitate hydratase 2 FIU16_00840 ENOG4108ZRK uncharacterized protein yacC FIU16_00845 ENOG4105E3B Multicopper oxidase FIU16_00850 ENOG4105DZG Dehydrogenase FIU16_00855 ENOG4108UGV hypoxanthine phosphoribosyltransferase FIU16_00860 ENOG41077A9 carbonic anhydrase FIU16_00865 ENOG4105DA5 (ABC) transporter FIU16_00870 ENOG4105E3A (ABC) transporter FIU16_00875 ENOG4108YTN IIa component FIU16_00880 ENOG4107BJW polysaccharide deacetylase FIU16_00890 ENOG4108A32 Transposase FIU16_00905 ENOG4105P0Q fimbrial-like protein YadC FIU16_00910 ENOG4105SN2 fimbrial-like adhesin protein FIU16_00915 ENOG4105SYG Fimbrial protein FIU16_00920 ENOG4108XEY fimbrial-like adhesin protein FIU16_00925 ENOG4105CW0 outer membrane usher protein FIU16_00930 ENOG4108VEV chaperone FIU16_00940 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FIU16_00945 ENOG4105DJ0 Poly(A) Polymerase FIU16_00950 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FIU16_00955 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FIU16_00965 ENOG4107XID 2'-5' rna ligase FIU16_00970 ENOG4105CQ7 ATP-dependent helicase FIU16_00975 ENOG4105BZ4 penicillin-binding protein FIU16_00980 ENOG4105E0K tonB-dependent siderophore receptor FIU16_00985 ENOG4105E0A ABC, transporter FIU16_00990 ENOG4105J76 Periplasmic binding protein FIU16_00995 ENOG4105S6R Iron-hydroxamate transporter permease subunit FIU16_01020 ENOG4105EN6 Membrane FIU16_01025 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FIU16_01040 ENOG4105C0H protease FIU16_01045 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FIU16_01065 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FIU16_01090 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FIU16_01095 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FIU16_01100 ENOG4105KNE Phosphatidate cytidylyltransferase FIU16_01105 ENOG4105DZP Membrane-associated zinc metalloprotease FIU16_01115 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FIU16_01120 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FIU16_01145 ENOG4105C0B DNA polymerase III (alpha subunit) FIU16_01155 ENOG4105CXN decarboxylase FIU16_01160 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FIU16_01165 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FIU16_01170 ENOG4105M1T rho-binding antiterminator FIU16_01180 ENOG4108VWS Yaeq family FIU16_01185 ENOG4108YZN class I peptide chain release factor FIU16_01190 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FIU16_01215 ENOG4108R96 Methyltransferase, YaeB family FIU16_01220 ENOG4108R8X outer membrane lipoprotein FIU16_01225 ENOG4105D01 (LipO)protein FIU16_01230 ENOG4108UMI ABC transporter, permease FIU16_01235 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FIU16_01240 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FIU16_01275 ENOG4105CV8 reductase FIU16_01280 ENOG4105HEI LysR family (Transcriptional regulator FIU16_01290 ENOG4105F2W methyltransferase FIU16_01295 ENOG4105E9H Lytic Murein transglycosylase FIU16_01305 ENOG4105D1A Methyltransferase FIU16_01315 ENOG4107RZZ dna polymerase iii epsilon subunit FIU16_01325 ENOG410600K aminopeptidase FIU16_01340 ENOG4105GMB type VI secretion system effector, hcp1 family FIU16_01365 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FIU16_01420 ENOG4108WC9 type VI secretion system effector, hcp1 family FIU16_01425 ENOG4105CS6 Rhs element vgr protein FIU16_01460 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FIU16_01465 ENOG4108WN0 inhibitor of vertebrate lysozyme FIU16_01470 ENOG4107QPN acyl-Coa dehydrogenase FIU16_01480 ENOG4105E7A Glutamine amidotransferase FIU16_01485 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FIU16_01490 ENOG4105VXN addiction module toxin, RelE StbE family FIU16_01500 ENOG4108YS0 lipoprotein YafL FIU16_01525 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FIU16_01530 ENOG4108HYG acetyltransferase FIU16_01540 ENOG4108S2Y peptide Chain Release factor FIU16_01545 ENOG4105CIN aminoacyl-histidine dipeptidase FIU16_01565 ENOG4105FCK Membrane FIU16_01660 ENOG4105F2I Transposase FIU16_01680 ENOG4107XAN XdhC and CoxI family FIU16_01685 ENOG4105C7W Xanthine dehydrogenase FIU16_01690 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FIU16_01695 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FIU16_01700 ENOG4105R3P Inner membrane protein yagU FIU16_01705 ENOG4105PI0 Ferredoxin FIU16_01710 ENOG4108UD7 cell wall organization FIU16_01715 ENOG4106PYX Receptor FIU16_01720 ENOG4108N3D putative enzyme FIU16_01730 ENOG4108GWT fimbrillin MatB FIU16_01785 ENOG4105F2I Transposase FIU16_01795 ENOG41066GK UPF0379 protein ykgI FIU16_01800 ENOG4107QN2 dihydrolipoyl dehydrogenase FIU16_01805 ENOG4108K01 transcriptional regulator FIU16_01810 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FIU16_01815 ENOG4107QR9 Iron-sulfur cluster binding protein FIU16_01820 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FIU16_01845 ENOG4105C94 Transporter FIU16_01855 ENOG4105BZU Histidine kinase FIU16_01860 ENOG4108NUU Transcriptional regulator FIU16_01865 ENOG4105SZ2 membrAne FIU16_01870 ENOG4107SNB ankyrin repeat protein YahD FIU16_01875 ENOG4105N16 Protein of unknown function (DUF2877) FIU16_01880 ENOG4107R1Q Membrane protein FdrA FIU16_01885 ENOG4107REC cytoplasmic protein FIU16_01890 ENOG4105C5B carbamate kinase FIU16_01895 ENOG4105DZC cytosine deaminase FIU16_01905 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FIU16_01910 ENOG4105C2J ABC transporter FIU16_01915 ENOG4105CNN ABC, transporter FIU16_01920 ENOG4105CNN ABC, transporter FIU16_01925 ENOG4105DQ4 alcohol dehydrogenase FIU16_01940 ENOG4105E82 cytochrome subunit of dehydrogenase FIU16_01945 ENOG4105TDT uncharacterized protein yahO FIU16_01950 ENOG4108JU7 Transcriptional regulator FIU16_01955 ENOG4105CR4 methylisocitrate lyase FIU16_01960 ENOG4105BZN citrate synthase FIU16_01965 ENOG4105DXD 2-methylcitrate dehydratase FIU16_01970 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FIU16_01975 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FIU16_01980 ENOG4105DZC cytosine deaminase FIU16_01985 ENOG4105DND Transcriptional regulator FIU16_01990 ENOG4107B2H carbonic anhydrase FIU16_02000 ENOG4105DJ2 Major Facilitator Superfamily FIU16_02005 ENOG4108UW5 maltose o-acetyltransferase FIU16_02010 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FIU16_02015 ENOG4105CNT hydrolase family 2 FIU16_02020 ENOG4105ETE Transcriptional regulator (LacI family FIU16_02025 ENOG4108K2P TRANSCRIPTIONal FIU16_02060 ENOG4108SC4 )-transporter FIU16_02065 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FIU16_02085 ENOG4105SRB Uncharacterized protein yaiO FIU16_02095 ENOG4108PBI Polysaccharide metabolism FIU16_02100 ENOG4107W19 lmbE family FIU16_02105 ENOG4106FTQ Taurine ABC transporter, periplasmic FIU16_02110 ENOG4108IY8 ABC, transporter FIU16_02115 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FIU16_02120 ENOG4105E2B Taurine dioxygenase FIU16_02125 ENOG4105D52 delta-aminolevulinic acid dehydratase FIU16_02135 ENOG4108PNB DNA-binding transcriptional regulator FIU16_02140 ENOG4107R6D beta-lactam binding protein AmpH FIU16_02145 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FIU16_02150 ENOG4107QS8 (LipO)protein FIU16_02155 ENOG4105FR5 inner membrane protein YaiY FIU16_02160 ENOG4105UNH Membrane FIU16_02165 ENOG4105CPF Cell wall formation (By similarity) FIU16_02175 ENOG4105G6Z alkaline phosphatase FIU16_02180 ENOG4105VIF phosphate starvation-inducible protein FIU16_02185 ENOG4105BZU Histidine kinase FIU16_02190 ENOG4105II7 pyrroline-5-carboxylate reductase FIU16_02205 ENOG4105SS3 FIU16_02210 ENOG4105HBA AroM protein FIU16_02230 ENOG4105DKQ ROK family FIU16_02235 ENOG4105F27 Major Facilitator FIU16_02240 ENOG4105EYH Exonuclease FIU16_02245 ENOG4107RH8 nuclease SbcCD subunit D FIU16_02250 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU16_02255 ENOG4105BZU Histidine kinase FIU16_02260 ENOG4105CWM branched-chain amino acid transport system II carrier protein FIU16_02265 ENOG4105C85 amino acid FIU16_02270 ENOG4107R28 alpha amylase, catalytic region FIU16_02290 ENOG4105VIE preprotein translocase, subunit YajC FIU16_02295 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FIU16_02300 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FIU16_02305 ENOG4105N1F Hnh endonuclease FIU16_02310 ENOG4105DRB nucleoside-specific channel-forming protein FIU16_02325 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FIU16_02330 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FIU16_02340 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FIU16_02345 ENOG4108ZAI phosphatidylglycerophosphatase a FIU16_02350 ENOG4105CPC Aldo Keto reductase FIU16_02360 ENOG4105CTB Polyprenyl synthetase FIU16_02375 ENOG4107S0N DJ-1 family FIU16_02380 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FIU16_02390 ENOG4107RDB Major Facilitator FIU16_02415 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FIU16_02420 ENOG4105CCU oxidase (Subunit III) FIU16_02425 ENOG4105BZ9 Cytochrome C oxidase, subunit I FIU16_02430 ENOG4105E2S oxidase) subunit II FIU16_02435 ENOG4105EYM Major Facilitator superfamily FIU16_02440 ENOG4105IEY (LipO)protein FIU16_02445 ENOG4105M85 Bola protein FIU16_02465 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FIU16_02470 ENOG4105K70 DNA-binding protein FIU16_02475 ENOG4105EIN peptidylprolyl cis-trans isomerase FIU16_02480 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FIU16_02485 ENOG4108TGP Thioesterase superfamily protein FIU16_02495 ENOG4108NFA extracellular solute-binding protein FIU16_02505 ENOG4108XM1 transcriptional regulator AsnC family FIU16_02510 ENOG4105BZ1 (ABC) transporter FIU16_02515 ENOG4105BZ1 (ABC) transporter FIU16_02520 ENOG4108YZA Nitrogen regulatory protein pii FIU16_02525 ENOG4105BZU Histidine kinase FIU16_02530 ENOG4105C29 acyl-CoA thioesterase FIU16_02535 ENOG4108MNP Glycoprotein polysaccharide metabolism FIU16_02540 ENOG41080UX Methyltransferase FIU16_02550 ENOG4105KCV RNA signal recognition particle 4.5S RNA FIU16_02555 ENOG41066DG (EAL) domain protein FIU16_02560 ENOG4105GSJ Inner membrane protein ylaC FIU16_02565 ENOG4108UW5 maltose o-acetyltransferase FIU16_02570 ENOG4105KF5 hemolysin expression-modulating protein FIU16_02575 ENOG4108UKR Biofilm formation regulator YbaJ FIU16_02580 ENOG4105BZS acriflavin resistance protein FIU16_02585 ENOG4105C1P efflux transporter, rnd family, mfp subunit FIU16_02590 ENOG4108IG5 Transcriptional regulator FIU16_02595 ENOG4105EGS Mechanosensitive ion channel FIU16_02600 ENOG4106428 Protein of unknown function (DUF2496) FIU16_02605 ENOG4108URS primosomal replication protein n'' FIU16_02610 ENOG4105WD1 Membrane FIU16_02620 ENOG4107QMP dna polymerase iii subunits gamma and tau FIU16_02635 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FIU16_02660 ENOG4107RE1 Inosine-guanosine kinase FIU16_02665 ENOG4105CKD glutathione-regulated potassium-efflux system protein FIU16_02670 ENOG4105EU0 Major facilitator Superfamily FIU16_02675 ENOG4105CGH 5'-nucleotidase FIU16_02680 ENOG4108Z66 YbaK ebsC protein FIU16_02685 ENOG4105MBR gumn family FIU16_02695 ENOG41081XE plasmid maintenance system antidote protein, xre family FIU16_02700 ENOG4105C59 p-type ATPase FIU16_02705 ENOG4105CSV Glutaminase FIU16_02710 ENOG4107RY6 amino acid FIU16_02715 ENOG4108Z6Z Transcriptional regulator FIU16_02720 ENOG4105G5H Membrane FIU16_02725 ENOG4107QX8 SPFH domain, Band 7 family protein FIU16_02730 ENOG41083J0 (ABC) transporter FIU16_02735 ENOG4105C4B ABC transporter, permease FIU16_02740 ENOG4107QR8 Thioredoxin FIU16_02745 ENOG4105E1F short-chain dehydrogenase reductase FIU16_02750 ENOG4108UJV acyl-CoA thioesterase i FIU16_02755 ENOG4108I0Y (ABC) transporter FIU16_02760 ENOG4105CV6 ABC transporter, permease FIU16_02765 ENOG4105CNA YD repeat protein FIU16_02795 ENOG4107653 Transcriptional regulator FIU16_02805 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region FIU16_02810 ENOG41060W2 glyoxylate carboligase FIU16_02815 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FIU16_02820 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FIU16_02825 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FIU16_02835 ENOG4105DTE Xanthine uracil vitamin C permease FIU16_02840 ENOG4105BZW Glycerate kinase FIU16_02845 ENOG4105S0E allantoin catabolism protein FIU16_02850 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FIU16_02855 ENOG4105DG4 malate L-lactate dehydrogenase FIU16_02860 ENOG4107R1Q Membrane protein FdrA FIU16_02865 ENOG4107REC cytoplasmic protein FIU16_02870 ENOG4105G5A Protein of unknown function (DUF2877) FIU16_02875 ENOG4105C5B carbamate kinase FIU16_02880 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FIU16_02885 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FIU16_02895 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FIU16_02905 ENOG4105S2T inner membrane protein YbcI FIU16_02910 ENOG4105WQ3 Rna-binding protein FIU16_02920 ENOG4108WDE Fimbrial protein FIU16_02925 ENOG4108AF8 Chaperone FIU16_02930 ENOG4105CW0 outer membrane usher protein FIU16_02935 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FIU16_02940 ENOG4108ZI2 Fimbrial protein FIU16_02945 ENOG4108Q9V regulatoR FIU16_02960 ENOG4105QUW FIU16_02965 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit FIU16_02970 ENOG410802X bacteriophage n4 adsorption protein b FIU16_02975 ENOG410600T transposase FIU16_02990 ENOG4105CNA YD repeat protein FIU16_03000 ENOG4105CS6 Rhs element vgr protein FIU16_03005 ENOG4105GR3 Histidine kinase FIU16_03010 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU16_03015 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FIU16_03020 ENOG410624V efflux system protein FIU16_03025 ENOG4105EP1 Efflux transporter rnd family, mfp subunit FIU16_03030 ENOG4108IJF Heavy metal efflux pump, CzcA FIU16_03035 ENOG4105C85 amino acid FIU16_03040 ENOG4105CUY Mechanosensitive ion channel FIU16_03045 ENOG4108RCM Nitroreductase FIU16_03050 ENOG4105MSB protein, conserved in bacteria FIU16_03055 ENOG4105WQ6 Membrane FIU16_03070 ENOG4107635 Hok Gef family protein FIU16_03075 ENOG4108SER Transposase FIU16_03085 ENOG4107635 Hok Gef family protein FIU16_03090 ENOG4108SER Transposase FIU16_03095 ENOG4108TSE Transferase FIU16_03100 ENOG4107RNH Outer membrane receptor FepA FIU16_03105 ENOG4105E93 esterase FIU16_03110 ENOG41085A6 mbth domain-containing protein FIU16_03115 ENOG4105C0W non-ribosomal peptide synthetase FIU16_03120 ENOG4108QY5 Ferric enterobactin transport protein FIU16_03125 ENOG4105E0A ABC, transporter FIU16_03130 ENOG4105TVJ transport system, permease FIU16_03135 ENOG4105DQ5 transport system permease protein FIU16_03145 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FIU16_03150 ENOG4105E4F Isochorismate synthase FIU16_03155 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FIU16_03160 ENOG4105WQI isochorismatase FIU16_03165 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FIU16_03170 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FIU16_03175 ENOG4105D22 carbon starvation protein FIU16_03180 ENOG4105VCD cytoplasmic protein FIU16_03185 ENOG4107SCQ Iron-containing alcohol dehydrogenase FIU16_03190 ENOG4105CHM Aminotransferase FIU16_03195 ENOG4105GTN ParB Domain Protein Nuclease FIU16_03200 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FIU16_03205 ENOG4105DQS Transcriptional regulator FIU16_03210 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FIU16_03215 ENOG4105D3R alkyl hydroperoxide reductase FIU16_03220 ENOG4108JU3 Alkyl hydroperoxide reductase FIU16_03225 ENOG4108U51 Universal stress protein FIU16_03230 ENOG4105E2A Dehydrogenase FIU16_03235 ENOG4105NXH GreA GreB family elongation factor FIU16_03240 ENOG4105KTS ribonuclease FIU16_03245 ENOG4107QPK )-transporter FIU16_03260 ENOG4105CHY citrate lyase, alpha FIU16_03265 ENOG4105CI0 Citrate lyase FIU16_03275 ENOG4105DUA (citrate (pro-3S)-lyase ligase FIU16_03280 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FIU16_03285 ENOG4106YYS transcriptional regulatory protein FIU16_03290 ENOG4105CEE C4-dicarboxylate transporter FIU16_03295 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FIU16_03300 ENOG4105VEQ Cold shock protein FIU16_03310 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FIU16_03315 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) FIU16_03325 ENOG41064T2 transcriptional regulator, lysR family FIU16_03340 ENOG4105DZ1 carboxypeptidase FIU16_03345 ENOG4105K6T rare lipoprotein A FIU16_03350 ENOG4105CNI cell division protein FtsW FIU16_03355 ENOG4105CJN penicillin-binding protein FIU16_03365 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FIU16_03370 ENOG4108TGR phosphatase FIU16_03380 ENOG4105DJF DNA polymerase III, delta' subunit FIU16_03395 ENOG4107PAI alpha helical protein FIU16_03400 ENOG4105EUU Sel1 domain protein repeat-containing protein FIU16_03405 ENOG41069CF Protein of unknown function (DUF1266) FIU16_03410 ENOG4105QFC Hsc56 co-chaperone of HscC FIU16_03415 ENOG4107JFD Sel1 repeat FIU16_03420 ENOG41069CF Protein of unknown function (DUF1266) FIU16_03425 ENOG4105QFC Hsc56 co-chaperone of HscC FIU16_03430 ENOG4105F7F Chaperone FIU16_03440 ENOG4105CDA abc transporter atp-binding protein FIU16_03445 ENOG4105DRP amino acid AbC transporter FIU16_03450 ENOG4105EAD ABC transporter FIU16_03455 ENOG4107RP9 extracellular solute-binding protein, family 3 FIU16_03470 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FIU16_03475 ENOG4108JU5 Magnesium and cobalt efflux protein FIU16_03485 ENOG4105C9A Phoh family FIU16_03495 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FIU16_03535 ENOG4105CAQ asparagine synthetase FIU16_03540 ENOG4105D4U had-superfamily hydrolase, subfamily iia FIU16_03545 ENOG4105E2R ROK family FIU16_03550 ENOG4105CE4 GlcNAc 6-P deacetylase FIU16_03560 ENOG4105CI1 PTS System FIU16_03575 ENOG4105GX6 (LipO)protein FIU16_03580 ENOG41090R7 Ferric uptake FIU16_03590 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FIU16_03595 ENOG4105NNH LexA regulated protein FIU16_03600 ENOG4105EV9 Alpha Beta Hydrolase FIU16_03605 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FIU16_03610 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FIU16_03615 ENOG4105D5Q Arginine ornithine antiporter FIU16_03620 ENOG4105CXN decarboxylase FIU16_03635 ENOG4105EEX Two component transcriptional regulator (Winged helix family FIU16_03640 ENOG4105C08 Histidine kinase FIU16_03665 ENOG4105XIQ Protein of unknown function (DUF2517) FIU16_03670 ENOG4105CNA YD repeat protein FIU16_03675 ENOG41079JQ Membrane FIU16_03685 ENOG4106R09 FIU16_03700 ENOG4107SEY Conserved Protein FIU16_03705 ENOG4105CVP deoxyribo-dipyrimidine photolyase FIU16_03710 ENOG4105DUX Transporter FIU16_03715 ENOG4107QNR UPF0135 protein FIU16_03720 ENOG4105P4J Allophanate hydrolase, subunit 1 FIU16_03725 ENOG4107R7A Allophanate hydrolase subunit 2 FIU16_03740 ENOG4108KK1 membrane protein AbrB duplication FIU16_03760 ENOG4106UBK fimbrial-like adhesin protein FIU16_03765 ENOG4105BZN citrate synthase FIU16_03775 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FIU16_03780 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FIU16_03785 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FIU16_03790 ENOG4105E33 succinate dehydrogenase FIU16_03795 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FIU16_03800 ENOG4105C7S Dehydrogenase FIU16_03810 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FIU16_03815 ENOG4105FDP GntR family transcriptional regulator FIU16_03820 ENOG4105DM4 PTS System FIU16_03825 ENOG4105C8I hydrolase, family 38 FIU16_03830 ENOG4105C4M (Ubiquinol oxidase) subunit I FIU16_03835 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FIU16_03845 ENOG4105KJB cyd operon protein YbgE FIU16_03850 ENOG4107YD3 Thioesterase FIU16_03855 ENOG4105E02 MotA TolQ exbB proton channel FIU16_03860 ENOG4105M8F Biopolymer transport protein exbD tolR FIU16_03865 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FIU16_03875 ENOG4105KCK Peptidoglycan-associated lipoprotein FIU16_03880 ENOG4105UFD tol-pal system protein YbgF FIU16_03930 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FIU16_03935 ENOG4105PGM cation diffusion facilitator family transporter FIU16_03940 ENOG4105JND homeobox protein FIU16_03945 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FIU16_03955 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FIU16_03965 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FIU16_03970 ENOG4105CMR udp-glucose 4-epimerase FIU16_03975 ENOG4105DKW ABC transporter FIU16_03980 ENOG4105F4R Transcriptional regulator mode FIU16_03985 ENOG410680R Protein of unknown function (DUF2592) FIU16_03990 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FIU16_03995 ENOG4105E0C molybdate abc transporter FIU16_04005 ENOG4108K4B hydrolase FIU16_04015 ENOG4105F04 LysR family Transcriptional regulator FIU16_04020 ENOG4105C7F AcnD-accessory protein PrpF FIU16_04025 ENOG4107QPK )-transporter FIU16_04030 ENOG4107QM5 aconitate hydratase FIU16_04035 ENOG4105NBR Pectinesterase FIU16_04040 ENOG4108I1J Integrase FIU16_04145 ENOG4107TII Recombinase FIU16_04165 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi FIU16_04170 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 FIU16_04175 ENOG4105RWQ Protein of unknown function (DUF1364) FIU16_04190 ENOG4105HRS Antitermination protein FIU16_04200 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_04205 ENOG4105KUS lysozyme FIU16_04210 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FIU16_04220 ENOG41064WM Uncharacterized protein YcgX FIU16_04225 ENOG4106YSC FIU16_04235 ENOG4105FKG DNA packaging protein FIU16_04245 ENOG4107DE1 head-to-tail joining protein FIU16_04255 ENOG4105F7J membrane-bound serine protease FIU16_04265 ENOG4105IM0 capsid protein FIU16_04340 ENOG410685N tail fiber protein FIU16_04345 ENOG4105UZW Tail fiber assembly protein FIU16_04350 ENOG4106KTS Inner membrane protein yeaI FIU16_04355 ENOG4108V1U phospholipid-binding protein FIU16_04360 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FIU16_04375 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FIU16_04380 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FIU16_04390 ENOG4105CHW UPF0052 protein FIU16_04400 ENOG4108RIR Molybdenum cofactor biosynthesis protein FIU16_04410 ENOG4105M00 molybdopterin converting factor, subunit 1 FIU16_04415 ENOG4108ZAF Molybdopterin FIU16_04420 ENOG4105HFZ Membrane FIU16_04430 ENOG410733J conserved inner membrane protein FIU16_04435 ENOG4107UXM Membrane FIU16_04440 ENOG4105DZQ phospholipase D Transphosphatidylase FIU16_04445 ENOG4105X23 Endonuclease Exonuclease phosphatase FIU16_04450 ENOG4105I9U inner membrane protein ybhQ FIU16_04455 ENOG4107QWP ABC-2 type transporter FIU16_04460 ENOG4107QWP ABC-2 type transporter FIU16_04465 ENOG4105CJ1 ABC, transporter FIU16_04475 ENOG4107MVR Transcriptional regulator FIU16_04480 ENOG4105C1J atp-dependent rna helicase FIU16_04485 ENOG4108UV1 cellular component movement FIU16_04490 ENOG4105DVT helicase FIU16_04495 ENOG4108MTB glycosyl transferase family FIU16_04500 ENOG4105DG4 malate L-lactate dehydrogenase FIU16_04505 ENOG4105VR4 UPF0379 protein ybiJ FIU16_04510 ENOG4105KSC Transcriptional regulator, TraR DksA family FIU16_04520 ENOG4108IU3 tonb-dependent siderophore receptor FIU16_04525 ENOG4105ZY9 UPF0379 protein ybiM FIU16_04535 ENOG4105D8X mechanosensitive ion channel FIU16_04540 ENOG4105CDA abc transporter atp-binding protein FIU16_04545 ENOG4105E5Q amino acid AbC transporter FIU16_04550 ENOG4107R0W ABC transporter FIU16_04560 ENOG4107AQZ Membrane FIU16_04570 ENOG4108T1M outer membrane protein x FIU16_04575 ENOG4108I6E Sulfatase FIU16_04585 ENOG4105KST dependent repressor FIU16_04590 ENOG4105F4P )-transporter FIU16_04595 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FIU16_04600 ENOG4105C5H ABC transporter FIU16_04615 ENOG41072TH Protein of unknown function (DUF1479) FIU16_04620 ENOG4108HCJ Hydrolase FIU16_04625 ENOG4105C6N Formate acetyltransferase FIU16_04630 ENOG4105F1A Pyruvate formate-lyase FIU16_04635 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FIU16_04640 ENOG4105D06 uba thif-type nad fad binding protein FIU16_04645 ENOG4105CVM Molybdenum cofactor synthesis domain protein FIU16_04650 ENOG4105D44 asparaginase FIU16_04670 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU16_04675 ENOG4105BZU Histidine kinase FIU16_04680 ENOG41064RH membrane protein YliF FIU16_04690 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FIU16_04695 ENOG4105D8V Glucose sorbosone dehydrogenase FIU16_04700 ENOG4108TGY Glutathione S-transferase FIU16_04705 ENOG4105DZ1 carboxypeptidase FIU16_04710 ENOG4107FB0 transcriptional regulator DeoR family FIU16_04715 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FIU16_04720 ENOG4107QF7 multi-drug FIU16_04730 ENOG4108HCJ Hydrolase FIU16_04735 ENOG4106UW1 Major Facilitator superfamily FIU16_04740 ENOG4108RFG Tetr family transcriptional regulator FIU16_04750 ENOG4105GWF inner membrane protein YbjM FIU16_04755 ENOG41090BQ Glutaredoxin FIU16_04760 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FIU16_04765 ENOG4108DBC nitroreductase FIU16_04775 ENOG4108RMJ sensory transduction regulator FIU16_04780 ENOG4107RUE extracellular solute-binding protein family 1 FIU16_04785 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FIU16_04790 ENOG4105F38 ABC transporter, permease FIU16_04795 ENOG4105D38 putrescine abc transporter FIU16_04800 ENOG4105RBQ inner membrane protein ybjO FIU16_04810 ENOG4106TNF Periplasmic binding protein FIU16_04815 ENOG4105DMR ABC, transporter FIU16_04820 ENOG4105GBT ABC transporter FIU16_04825 ENOG4106PMH Extracellular solute-binding protein family 3 FIU16_04830 ENOG4105E5Z arginine transporter ATP-binding subunit FIU16_04835 ENOG41064MM (LipO)protein FIU16_04845 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FIU16_04850 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FIU16_04855 ENOG4105CGD Nad-dependent epimerase dehydratase FIU16_04860 ENOG4105C5W Aldolase FIU16_04865 ENOG4105C7K acetolactate synthase FIU16_04870 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FIU16_04880 ENOG4105DWU Membrane FIU16_04885 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FIU16_04890 ENOG4105CPB ATP-dependent endonuclease of the OLD family FIU16_04895 ENOG4108MJ5 VirK protein FIU16_04900 ENOG4105DJY efflux transporter, rnd family, mfp subunit FIU16_04910 ENOG4105VEQ Cold shock protein FIU16_04920 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FIU16_04935 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FIU16_04945 ENOG4108JJ8 (ABC) transporter FIU16_04950 ENOG4108JJ9 ABC, transporter FIU16_04955 ENOG4105C3M thioredoxin reductase FIU16_04960 ENOG4105EW9 transcriptional regulator AsnC family FIU16_04965 ENOG4105CNU cell division protein FtsK FIU16_04975 ENOG4105D1H recombination factor protein RarA FIU16_04985 ENOG4107QY8 reductase FIU16_04990 ENOG4105QAX Iron-sulfur FIU16_04995 ENOG4107KGK dmso reductase anchor subunit FIU16_05000 ENOG4105CHJ isochorismatase hydrolase FIU16_05010 ENOG4105E5D amino acid FIU16_05015 ENOG410642W LysR family Transcriptional regulator FIU16_05020 ENOG4108X0B nad(p)h dehydrogenase (quinone) FIU16_05025 ENOG4105F1A Pyruvate formate-lyase FIU16_05030 ENOG4105C6N Formate acetyltransferase FIU16_05035 ENOG4105TMB Formate nitrite transporter FIU16_05040 ENOG4105DDY UPF0142 protein ycaO FIU16_05045 ENOG4107VMU Membrane FIU16_05060 ENOG4108K0D peptidase, M48 FIU16_05070 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FIU16_05080 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FIU16_05085 ENOG4105BZ1 (ABC) transporter FIU16_05095 ENOG4105T0Z Conserved Protein FIU16_05110 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FIU16_05115 ENOG4107S90 membrAne FIU16_05120 ENOG4106371 Methyltransferase FIU16_05130 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FIU16_05140 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FIU16_05145 ENOG4105EAQ (twin-arginine translocation) pathway signal FIU16_05150 ENOG4105C5X domain protein FIU16_05165 ENOG4105CGF Aromatic amino acid aminotransferase FIU16_05170 ENOG4105FCK Membrane FIU16_05185 ENOG4105CD8 aminopeptidase N FIU16_05195 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FIU16_05205 ENOG4105GVF (ABC) transporter FIU16_05210 ENOG4108UZX fmn reductase FIU16_05215 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon FIU16_05220 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae FIU16_05225 ENOG4105CW0 outer membrane usher protein FIU16_05230 ENOG4108MDY Fimbrial FIU16_05235 ENOG4105Q7J Fimbrial FIU16_05240 ENOG4105MX3 Fimbrial FIU16_05245 ENOG4106PH7 chaperone FIU16_05255 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FIU16_05260 ENOG4105QVC MOSC domain-containing protein FIU16_05270 ENOG4105C5H ABC transporter FIU16_05275 ENOG4105F1S paraquat-inducible protein a FIU16_05280 ENOG4105DY2 Paraquat-inducible protein b FIU16_05285 ENOG4108Q2G (LipO)protein FIU16_05290 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FIU16_05300 ENOG4105DAN ATP-dependent protease FIU16_05310 ENOG4105UYK outer membrane protein a FIU16_05320 ENOG4108RZ1 DNA transformation protein FIU16_05325 ENOG4105EM2 membrane FIU16_05330 ENOG410901E Membrane FIU16_05335 ENOG41088T4 Helicase IV FIU16_05350 ENOG4105K4P CoA-binding domain protein FIU16_05365 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FIU16_05370 ENOG4108Z0T Part of a sulfur-relay system (By similarity) FIU16_05375 ENOG4108MN8 Membrane FIU16_05385 ENOG4105E3S small subunit FIU16_05390 ENOG4105DPX Hydrogenase, large subunit FIU16_05395 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FIU16_05400 ENOG4108USZ hydrogenase FIU16_05405 ENOG4108VXY Hydrogenase-1 operon protein HyaE FIU16_05410 ENOG4105MVP hydrogenase-1 operon protein HyaF FIU16_05415 ENOG4105C4M (Ubiquinol oxidase) subunit I FIU16_05420 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FIU16_05430 ENOG4105D6F Phosphatase FIU16_05435 ENOG4105D75 Capsular exopolysaccharide family FIU16_05440 ENOG4107ZF2 Phosphatase FIU16_05445 ENOG4105DAY polysaccharide export protein FIU16_05450 ENOG4105E3R (LipO)protein FIU16_05455 ENOG4108W78 Pfam:DUF1017 FIU16_05460 ENOG4108Y9B (LipO)protein FIU16_05470 ENOG41060EU Cold shock-like protein FIU16_05475 ENOG4105VEQ Cold shock protein FIU16_05490 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FIU16_05495 ENOG4105HEE Binding Domain protein FIU16_05500 ENOG4105BZU Histidine kinase FIU16_05505 ENOG4108SV3 Tmao reductase system periplasmic protein tort FIU16_05510 ENOG4106WF9 DNA-binding transcriptional regulator TorR FIU16_05515 ENOG4105CUW cytochrome C-TYPE protein FIU16_05520 ENOG4108J2R molybdopterin oxidoreductase FIU16_05545 ENOG4105D6F Phosphatase FIU16_05550 ENOG4105XH3 FIU16_05560 ENOG4107R08 Integrase FIU16_05600 ENOG4105XB7 anti-repressor protein FIU16_05605 ENOG4105XB7 anti-repressor protein FIU16_05635 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) FIU16_05640 ENOG4105H40 FIU16_05675 ENOG4106050 phage regulatory protein, rha family FIU16_05735 ENOG4105HRS Antitermination protein FIU16_05790 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_05810 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FIU16_05815 ENOG4105QYK bacteriophage lambda Bor protein homolog FIU16_05870 ENOG4108X9F tail fiber protein FIU16_05870 ENOG4108X9F tail fiber protein FIU16_05900 ENOG4108T1M outer membrane protein x FIU16_05950 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FIU16_05955 ENOG4105C2W permease FIU16_05990 ENOG4108R86 Transcriptional regulator FIU16_05995 ENOG4105C26 Dehydrogenase FIU16_06005 ENOG4105CK7 Sodium proline symporter FIU16_06010 ENOG4105EKT )-iron permease FIU16_06015 ENOG410650H (LipO)protein FIU16_06020 ENOG4105DBE peroxidase FIU16_06025 ENOG4105D5M phosphate starvation-inducible protein FIU16_06030 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FIU16_06035 ENOG4105CND Glycosyl transferase, family 2 FIU16_06040 ENOG4107BJW polysaccharide deacetylase FIU16_06045 ENOG4108TUY outer membrane protein PgaA FIU16_06050 ENOG4105BZU Histidine kinase FIU16_06065 ENOG4108T85 Membrane FIU16_06075 ENOG4105DFP Integrase FIU16_06115 ENOG4108YXQ IS66 Orf2 family protein FIU16_06130 ENOG4105D05 Receptor FIU16_06195 ENOG4105F2I Transposase FIU16_06220 ENOG41090Q8 at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP FIU16_06225 ENOG4108MBX Secretion Protein FIU16_06230 ENOG4108JJA ABC, transporter FIU16_06315 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FIU16_06325 ENOG4107YNJ LysR family Transcriptional regulator FIU16_06365 ENOG4108M24 von Willebrand factor, type A FIU16_06370 ENOG4108M24 von Willebrand factor, type A FIU16_06400 ENOG4105DAX Pfam:DUF2983 FIU16_06480 ENOG4108F5E vimentin FIU16_06485 ENOG4108YIV FIU16_06510 ENOG4108YXQ IS66 Orf2 family protein FIU16_06515 ENOG4105E5H Transposase FIU16_06525 ENOG4106H6R UPF0380 protein FIU16_06535 ENOG4106549 Antirestriction protein FIU16_06540 ENOG4108YGG dna repair protein FIU16_06545 ENOG4106WJE Protein of unknown function (DUF987) FIU16_06550 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FIU16_06590 ENOG4107XHZ cytoplasmic chaperone TorD family protein FIU16_06595 ENOG4108UQ5 membrane protein YcdZ FIU16_06600 ENOG4105P8Q Curli production assembly transport component CsgG FIU16_06605 ENOG4108WYR Curli production assembly transport component, CsgF FIU16_06610 ENOG4108XDW curli assembly protein CsgE FIU16_06615 ENOG41086KC Transcriptional regulator FIU16_06620 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FIU16_06625 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin FIU16_06640 ENOG4108UVJ appr-1-p processing domain protein FIU16_06645 ENOG4107RZC phospholipase d FIU16_06660 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FIU16_06665 ENOG4105NAC (LipO)protein FIU16_06670 ENOG4108W47 Acidic protein msyB FIU16_06680 ENOG4105D1S lipid A biosynthesis FIU16_06690 ENOG4108YYC ycei family FIU16_06695 ENOG4105DS1 cytochrome b561 FIU16_06700 ENOG4106974 biofilm formation FIU16_06710 ENOG4105PVA Biofilm formation regulatory protein BssS FIU16_06715 ENOG4105MEA DNA damage-inducible protein i FIU16_06725 ENOG4105F3T (LipO)protein FIU16_06730 ENOG4105E9S glutaredoxin 2 FIU16_06740 ENOG4105D9U N-acetyltransferase FIU16_06750 ENOG4105EP9 oxidoreductase FIU16_06755 ENOG4105CJR Integral membrane protein (MviN FIU16_06760 ENOG4105QVD Flagella synthesis protein FlgN FIU16_06765 ENOG4105M9M anti-sigma28 factor FlgM FIU16_06770 ENOG4105CKS Flagella basal body P-ring formation protein flgA FIU16_06775 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FIU16_06780 ENOG4108ZC9 flagellar basal-body rod protein flgc FIU16_06785 ENOG4105W00 Flagellar hook capping protein FIU16_06790 ENOG4105BZE flagellar hook protein, FlgE FIU16_06795 ENOG4108KPB Flagellar basal-body rod protein FlgF FIU16_06800 ENOG4105CGA flagellar basal-body rod protein FlgG FIU16_06815 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FIU16_06820 ENOG4105E1Q flagellar hook-associated protein FIU16_06825 ENOG4105DTJ flagellar hook-associated protein FIU16_06830 ENOG4107QQB Ribonuclease E FIU16_06835 ENOG4105EI2 Pseudouridine synthase FIU16_06840 ENOG4108UHJ MAF-like protein FIU16_06845 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FIU16_06865 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FIU16_06870 ENOG4105CHR reductase FIU16_06875 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FIU16_06880 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FIU16_06885 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FIU16_06890 ENOG4105HHA aminodeoxychorismate lyase FIU16_06900 ENOG4107QRG dna polymerase iii FIU16_06905 ENOG4105F8V Hydrolase, tatD family FIU16_06910 ENOG4105CI1 PTS System FIU16_06915 ENOG4105CNM Receptor FIU16_06920 ENOG4105K59 histidine triad (HIT) protein FIU16_06925 ENOG41090DQ Lipoprotein FIU16_06930 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FIU16_06950 ENOG4105CEP NADH dehydrogenase FIU16_06955 ENOG4107MBR 17 kDa surface antigen FIU16_06960 ENOG4108IND Tetr family transcriptional regulator FIU16_06965 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FIU16_06970 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FIU16_06975 ENOG4108JA2 transcriptioN-repair coupling factor FIU16_06980 ENOG4105IQC Inner membrane protein YcfT FIU16_06985 ENOG4105D60 lipoprotein releasing system transmembrane protein FIU16_06990 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FIU16_06995 ENOG4105D60 lipoprotein releasing system transmembrane protein FIU16_07005 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FIU16_07020 ENOG4107RUE extracellular solute-binding protein family 1 FIU16_07025 ENOG4105D38 putrescine abc transporter FIU16_07030 ENOG4108I1J Integrase FIU16_07040 ENOG41076J9 exonuclease VIII FIU16_07045 ENOG4106G8A Qin prophage FIU16_07095 ENOG4105YQ0 FIU16_07165 ENOG4105WI6 cell killing protein encoded within cryptic prophage FIU16_07180 ENOG4108MXB Protein of unknown function (DUF968) FIU16_07185 ENOG4105KSK (crossover) junction endodeoxyribonuclease FIU16_07190 ENOG4105HGD Antitermination protein FIU16_07225 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_07245 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FIU16_07255 ENOG4106YSC FIU16_07270 ENOG4105UZW Tail fiber assembly protein FIU16_07295 ENOG4105IM0 capsid protein FIU16_07370 ENOG4108X9F tail fiber protein FIU16_07375 ENOG4105UZW Tail fiber assembly protein FIU16_07380 ENOG4105F38 ABC transporter, permease FIU16_07385 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FIU16_07395 ENOG4105EZE Cupin 4 family protein FIU16_07400 ENOG4105IFJ Histidine kinase FIU16_07405 ENOG4105XJC Two component transcriptional regulator (Winged helix family FIU16_07410 ENOG4107QTF adenylosuccinate lyase FIU16_07430 ENOG4108R99 pseudouridine synthase FIU16_07435 ENOG4108HMX isocitrate dehydrogenase (NADP) FIU16_07450 ENOG41064WM Uncharacterized protein YcgX FIU16_07455 ENOG4108XDN Transcriptional regulator FIU16_07460 ENOG4105BZU Histidine kinase FIU16_07465 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component FIU16_07470 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB FIU16_07480 ENOG410738I uncharacterized protein ymgC FIU16_07485 ENOG4105BZU Histidine kinase FIU16_07505 ENOG410658X FIU16_07540 ENOG4107QMS site-determining protein FIU16_07550 ENOG4105S66 prophage protein FIU16_07555 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FIU16_07565 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FIU16_07585 ENOG4105KT5 UmuD protein FIU16_07590 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FIU16_07595 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FIU16_07610 ENOG4105ED1 spovr family FIU16_07620 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FIU16_07630 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FIU16_07640 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FIU16_07660 ENOG4105VDH Dihydroxyacetone kinase FIU16_07665 ENOG4108UTZ Dihydroxyacetone kinase FIU16_07670 ENOG4105CMT Dihydroxyacetone kinase FIU16_07675 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FIU16_07680 ENOG4105I1J Autotransporter FIU16_07685 ENOG4105C3G gtp-binding protein FIU16_07695 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FIU16_07700 ENOG4105CHH sulfate transporter FIU16_07705 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FIU16_07730 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FIU16_07735 ENOG4108YY7 Invasion gene expression up-regulator SirB FIU16_07740 ENOG41063JG Transcriptional regulator FIU16_07780 ENOG4105EWV Sodium calcium exchanger membrane region FIU16_07785 ENOG4105WS7 Cation transport regulator FIU16_07790 ENOG4108NH8 Cation transport protein FIU16_07795 ENOG41090EX DsrE family FIU16_07800 ENOG4105ID0 Putative invasin FIU16_07805 ENOG4105WH1 Two component transcriptional regulator luxr family FIU16_07810 ENOG4105BZU Histidine kinase FIU16_07815 ENOG4105DQQ Major facilitator superfamily MFS_1 FIU16_07820 ENOG4105CRU nitrate reductase, alpha subunit FIU16_07825 ENOG4108IUE nitrate reductase beta subunit FIU16_07830 ENOG4105R3A Nitrate reductase FIU16_07835 ENOG41076YT nitrate reductase, gamma subunit FIU16_07855 ENOG4105CIY formyltetrahydrofolate deformylase FIU16_07865 ENOG4105D78 K07001 NTE family protein FIU16_07870 ENOG4105I93 response regulator FIU16_07875 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FIU16_07880 ENOG4108SAU DNA-binding protein H-ns FIU16_07885 ENOG4107104 thymidine kinase FIU16_07895 ENOG4108EKI Dehydrogenase FIU16_07900 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FIU16_07905 ENOG4108J59 Extracellular solute-binding protein, family 5 FIU16_07915 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU16_07920 ENOG4105C3U ABC transporter FIU16_07925 ENOG4108JQ7 (ABC) transporter FIU16_07945 ENOG4107SVH Potassium channel protein FIU16_07950 ENOG4105K9H YciI-like protein FIU16_07955 ENOG410822N TonB family FIU16_07960 ENOG4105NAU thioesterase Superfamily protein FIU16_07980 ENOG4105EIF outer membrane protein W FIU16_07985 ENOG4108I1J Integrase FIU16_08000 ENOG4106G8A Qin prophage FIU16_08040 ENOG4105YQ0 FIU16_08050 ENOG4105WPN DNA integration recombination invertion protein FIU16_08055 ENOG4105WI6 cell killing protein encoded within cryptic prophage FIU16_08070 ENOG4108MXB Protein of unknown function (DUF968) FIU16_08075 ENOG4105KSK (crossover) junction endodeoxyribonuclease FIU16_08080 ENOG4105HGD Antitermination protein FIU16_08130 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_08190 ENOG4105UZW Tail fiber assembly protein FIU16_08215 ENOG4105IM0 capsid protein FIU16_08295 ENOG4108X9F tail fiber protein FIU16_08300 ENOG4105UZW Tail fiber assembly protein FIU16_08310 ENOG4108WF3 methyltransferase FIU16_08325 ENOG4108N8X transition metal ion binding FIU16_08330 ENOG4108Z9Z response to DNA damage stimulus FIU16_08350 ENOG4105DK0 Indole-3-glycerol phosphate synthase FIU16_08355 ENOG4108EFP Anthranilate synthase component II FIU16_08360 ENOG4105CRQ synthase (Component I) FIU16_08370 ENOG4105DB7 PHP domain protein FIU16_08375 ENOG4107RTD sua5 ycio yrdc ywlc family protein FIU16_08380 ENOG4105FE9 pseudouridine synthase FIU16_08385 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FIU16_08390 ENOG4105UBK short-chain dehydrogenase reductase FIU16_08395 ENOG4105ERU peptidase FIU16_08400 ENOG4105RKX Protein of unknown function (DUF2498) FIU16_08405 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FIU16_08410 ENOG4107R11 Transcriptional regulator FIU16_08430 ENOG4107QM5 aconitate hydratase FIU16_08440 ENOG4105EYK Phosphatidylglycerophosphatase B FIU16_08445 ENOG4105Q4A inner membrane protein yciS FIU16_08450 ENOG4105CFV Tetratricopeptide repeat protein FIU16_08460 ENOG4108ZJT translation initiation factor, Sui1 FIU16_08465 ENOG41061RM osmotically inducible lipoprotein FIU16_08470 ENOG4105N2W Transcriptional regulator FIU16_08480 ENOG4105BZU Histidine kinase FIU16_08495 ENOG4105Q4T oxidoreductase FIU16_08500 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FIU16_08505 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FIU16_08510 ENOG4108JQ2 peptide transport system atp-binding protein FIU16_08515 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FIU16_08520 ENOG4108EU3 peptide transport system, permease FIU16_08525 ENOG4108I5W peptide transport system, permease protein FIU16_08530 ENOG4108HIY periplasmic FIU16_08535 ENOG4105N0E Protein of unknown function (DUF2543) FIU16_08540 ENOG4105CUB amino acid FIU16_08550 ENOG4105CFQ glutamine synthetase FIU16_08555 ENOG4108Z86 Glutamine amidotransferase FIU16_08560 ENOG4107VRI Transcriptional regulator FIU16_08565 ENOG4105C26 Dehydrogenase FIU16_08570 ENOG4105CJP fad dependent oxidoreductase FIU16_08575 ENOG4108JPW Aminotransferase FIU16_08580 ENOG4105E51 psp operon transcriptional activator FIU16_08585 ENOG41087YS Phage shock protein A FIU16_08590 ENOG4105YYT phage shock protein B FIU16_08595 ENOG4105FM1 phage shock protein C FIU16_08600 ENOG4105NNG Peripheral inner membrane phage-shock protein FIU16_08605 ENOG4105K8Z Phage shock protein FIU16_08610 ENOG4107QW3 Sucrose phosphorylase FIU16_08615 ENOG4105WEM extracellular solute-binding protein FIU16_08620 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FIU16_08625 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FIU16_08630 ENOG4107RRD Dehydrogenase FIU16_08635 ENOG4107TYA transient receptor potential locus FIU16_08640 ENOG4105CK5 oxidoreductase FIU16_08645 ENOG4105C71 hydrolase family 65, central catalytic FIU16_08650 ENOG4107URF beta-phospho-glucomutase FIU16_08655 ENOG4108IJ9 (ABC) transporter FIU16_08660 ENOG4107EFV Outer membrane protein G FIU16_08665 ENOG4105FKQ transcriptional regulator FIU16_08670 ENOG4105CM6 amino acid regulated cytosolic protein FIU16_08680 ENOG4108JU8 Transcriptional regulator FIU16_08685 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FIU16_08690 ENOG4107S8C mandelate racemase muconate lactonizing FIU16_08695 ENOG4105KXI murein peptide amidase A FIU16_08710 ENOG4105ENX hydrolase FIU16_08715 ENOG4105EQ2 LysR family Transcriptional regulator FIU16_08720 ENOG4107QSI ABC, transporter FIU16_08725 ENOG4105D64 Mechanosensitive ion channel FIU16_08730 ENOG4105S5I Membrane FIU16_08735 ENOG4105Q9Y Universal stress protein FIU16_08740 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FIU16_08745 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FIU16_08750 ENOG4105CFC Transporter FIU16_08755 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B FIU16_08760 ENOG4105CH2 amidohydrolase FIU16_08765 ENOG4106KR7 LysR family Transcriptional regulator FIU16_08770 ENOG4108DG9 Smr protein MutS2 FIU16_08775 ENOG4105BZU Histidine kinase FIU16_08785 ENOG4105C1J atp-dependent rna helicase FIU16_08795 ENOG4108RW8 Universal stress protein F FIU16_08800 ENOG4105FCK Membrane FIU16_08805 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FIU16_08815 ENOG41090X5 Heat shock protein hslJ FIU16_08820 ENOG4105C5I Dehydrogenase FIU16_08825 ENOG4107H52 Dicarboxylate transport FIU16_08830 ENOG410689M (LipO)protein FIU16_08835 ENOG4105WXT Conserved Protein FIU16_08840 ENOG4108WFR AraC Family Transcriptional Regulator FIU16_08845 ENOG4105C26 Dehydrogenase FIU16_08850 ENOG4105F11 amine oxidase FIU16_08855 ENOG4105DXM phenylacetic acid degradation protein FIU16_08860 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FIU16_08865 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FIU16_08870 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FIU16_08875 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FIU16_08880 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FIU16_08885 ENOG4105E39 Enoyl-CoA hydratase FIU16_08890 ENOG4108UKI Enoyl-CoA hydratase FIU16_08895 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FIU16_08900 ENOG4108ZJI phenylacetic acid degradation protein FIU16_08905 ENOG4105CHU acetyl-coa acetyltransferase FIU16_08910 ENOG4105DZS Phenylacetate-CoA ligase FIU16_08915 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FIU16_08920 ENOG4108Z0R Transferase FIU16_08925 ENOG4107S5I aldo keto reductase FIU16_08935 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FIU16_08940 ENOG4108HPI phosphatidate Cytidylyltransferase FIU16_08945 ENOG4105E8V Alpha Beta Hydrolase Fold protein FIU16_08950 ENOG41077RS Phosphatase FIU16_08960 ENOG4105CQ7 ATP-dependent helicase FIU16_08965 ENOG4107DB1 DUF218 domain FIU16_08970 ENOG4105C26 Dehydrogenase FIU16_08975 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FIU16_08980 ENOG4105CPW cytochrome b561 FIU16_08985 ENOG4105UPP uncharacterized protein ydcA FIU16_08990 ENOG4107NK6 Hok/gef family FIU16_08995 ENOG4105C8Q Methyl-accepting chemotaxis FIU16_09000 ENOG4105DDW LysR family Transcriptional regulator FIU16_09005 ENOG4105E32 cytoplasmic protein FIU16_09015 ENOG4105Z2P Protein of unknown function (DUF465) FIU16_09020 ENOG4108Z9I -acetyltransferase FIU16_09025 ENOG4107WE3 acetyltransferase YdcK FIU16_09030 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FIU16_09035 ENOG41088CC tellurite resistance protein tehB FIU16_09040 ENOG4108KKZ (LipO)protein FIU16_09050 ENOG4105D7V transposase FIU16_09055 ENOG4105DKK Benzoate FIU16_09060 ENOG4108JCI Transcriptional regulator FIU16_09065 ENOG4105CFP Peptidase U32 FIU16_09070 ENOG4105RR0 Protein of unknown function (DUF2554) FIU16_09080 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FIU16_09085 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU16_09090 ENOG4107TYH extracellular solute-binding protein family 1 FIU16_09095 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FIU16_09100 ENOG4105D81 ABC transporter, permease FIU16_09105 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component FIU16_09125 ENOG410654E Membrane FIU16_09130 ENOG4105R71 cytoplasmic protein FIU16_09135 ENOG4108T9Y Inner membrane protein ydcZ FIU16_09140 ENOG4108Z7F N-acetyltransferase FIU16_09145 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FIU16_09150 ENOG4108WYP Transcriptional regulator FIU16_09155 ENOG4105CHB tonB-dependent Receptor FIU16_09160 ENOG4108NS2 receptor FIU16_09165 ENOG4105C85 amino acid FIU16_09170 ENOG4108N27 Glutathione S-transferase FIU16_09180 ENOG4105CS6 Rhs element vgr protein FIU16_09185 ENOG4105CNA YD repeat protein FIU16_09205 ENOG4108MEJ flavin reductase domain protein FIU16_09210 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FIU16_09215 ENOG4105JAB phenazine biosynthesis protein, phzf family FIU16_09220 ENOG4105D0D Nitrate reductase 2, gamma subunit FIU16_09225 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FIU16_09230 ENOG4108IUE nitrate reductase beta subunit FIU16_09235 ENOG4105CRU nitrate reductase, alpha subunit FIU16_09240 ENOG4107QND Nitrite extrusion protein FIU16_09245 ENOG4108UI3 Leucine Rich repeat FIU16_09255 ENOG4105RPH Inner membrane protein YddG FIU16_09265 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FIU16_09270 ENOG4108MG3 formate dehydrogenase FIU16_09275 ENOG41084S7 Plasmid maintenance system antidote protein FIU16_09280 ENOG4105DQ4 alcohol dehydrogenase FIU16_09290 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein FIU16_09295 ENOG4105TPS biofilm-dependent modulation protein FIU16_09300 ENOG4108Z9K Osmotically inducible protein FIU16_09305 ENOG4107H6U ABC transporter FIU16_09310 ENOG4105C3U ABC transporter FIU16_09315 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU16_09320 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FIU16_09325 ENOG4105DEF Extracellular solute-binding protein, family 5 FIU16_09330 ENOG4108UQS dipeptidase FIU16_09335 ENOG4105BZU Histidine kinase FIU16_09345 ENOG4105F32 YngK protein FIU16_09350 ENOG4105E5D amino acid FIU16_09355 ENOG4105CVK Glutamate decarboxylase FIU16_09360 ENOG4107RAN Peptidase, M16 FIU16_09365 ENOG4105PE1 Receptor FIU16_09370 ENOG4105CQ0 ABC transporter FIU16_09380 ENOG4105C4X radical SAM domain protein FIU16_09390 ENOG4105F2I Transposase FIU16_09400 ENOG4105Z68 AraC Family Transcriptional Regulator FIU16_09410 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FIU16_09415 ENOG4106PIH fimbrial-like protein ydeQ FIU16_09420 ENOG4106318 fimbrial-like protein YdeR FIU16_09425 ENOG4108WDE Fimbrial protein FIU16_09430 ENOG4105CW0 outer membrane usher protein FIU16_09440 ENOG4108RQP Major type 1 subunit fimbrin FIU16_09450 ENOG4105CAF HipA N-terminal domain protein FIU16_09455 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein FIU16_09475 ENOG4105DKT Transcriptional regulator FIU16_09490 ENOG4105F5R ABC transporter FIU16_09495 ENOG4105D4B ABC, transporter FIU16_09505 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FIU16_09515 ENOG4105FFC UPF0187 protein FIU16_09525 ENOG4105BZU Histidine kinase FIU16_09530 ENOG4105M0C cytoplasmic protein FIU16_09535 ENOG4105CSV Glutaminase FIU16_09540 ENOG4105C26 Dehydrogenase FIU16_09545 ENOG4105EGI Transcriptional regulator FIU16_09570 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FIU16_09575 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FIU16_09580 ENOG4106DNR multiple antibiotic resistance protein FIU16_09585 ENOG4105CS2 ec 3.2.1.21 FIU16_09595 ENOG4105VCP PTS System FIU16_09600 ENOG4105CK1 PTS System FIU16_09610 ENOG4105FDP GntR family transcriptional regulator FIU16_09615 ENOG4108594 Permease of the drug metabolite transporter FIU16_09620 ENOG4105E5W Transporter FIU16_09630 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FIU16_09635 ENOG4108YDI single-species biofilm formation on inanimate substrate FIU16_09640 ENOG4108WTK competence damage-inducible protein FIU16_09645 ENOG4105DGW oligopeptidase A FIU16_09650 ENOG4105EMU Dehydrogenase FIU16_09655 ENOG4107XBN GntR Family Transcriptional Regulator FIU16_09660 ENOG41061EV selenium-binding protein YdfZ FIU16_09665 ENOG4105DEI Mannitol dehydrogenase FIU16_09675 ENOG4105CPQ Dehydrogenase FIU16_09680 ENOG4105CXK mandelate racemase muconate lactonizing FIU16_09695 ENOG4108MK9 spermidine N(1)-acetyltransferase FIU16_09705 ENOG4105KBG Protein of unknown function (DUF1161) FIU16_09710 ENOG4107QY8 reductase FIU16_09715 ENOG4105C3J Cysteine desulfurase FIU16_09720 ENOG4105QAX Iron-sulfur FIU16_09725 ENOG4105XB7 anti-repressor protein FIU16_09805 ENOG4108T1M outer membrane protein x FIU16_09915 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_09940 ENOG4105HRS Antitermination protein FIU16_09955 ENOG4105RWQ Protein of unknown function (DUF1364) FIU16_09965 ENOG4105NY2 NinB protein FIU16_10000 ENOG4105WI6 cell killing protein encoded within cryptic prophage FIU16_10025 ENOG4105JBR DNA replication protein FIU16_10075 ENOG4107712 FIU16_10095 ENOG41076J9 exonuclease VIII FIU16_10125 ENOG4108KU3 Integrase FIU16_10130 ENOG4105QAX Iron-sulfur FIU16_10135 ENOG4107KGK dmso reductase anchor subunit FIU16_10140 ENOG4108NEM leader-binding protein dmsD FIU16_10150 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FIU16_10155 ENOG4105DAG ROK family FIU16_10160 ENOG4106NZI LysR family Transcriptional regulator FIU16_10165 ENOG4105D94 Major Facilitator Superfamily FIU16_10180 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FIU16_10200 ENOG4105DSF transport protein FIU16_10205 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FIU16_10210 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FIU16_10215 ENOG4105C5D exported protein FIU16_10220 ENOG4105D5Q Arginine ornithine antiporter FIU16_10230 ENOG4105RA2 Membrane FIU16_10235 ENOG4107EXC regulatoR FIU16_10240 ENOG4105JJR Histidine kinase FIU16_10250 ENOG4105C9Q fumarate hydratase class II FIU16_10255 ENOG4107GFK fumarate FIU16_10260 ENOG4105EIP mannose-6-phosphate isomerase FIU16_10265 ENOG4106J39 exported protein FIU16_10270 ENOG4108QNI outer membrane porin protein FIU16_10275 ENOG4105CT4 transporter FIU16_10280 ENOG4105CNT hydrolase family 2 FIU16_10285 ENOG4105XEA Tetr family transcriptional regulator FIU16_10290 ENOG4107ZQV short-chain dehydrogenase reductase FIU16_10295 ENOG4107P2S Transcriptional regulator FIU16_10300 ENOG4105CI1 PTS System FIU16_10305 ENOG4105C87 Aminotransferase class I and II FIU16_10315 ENOG4105D9R oxidoreductase FIU16_10320 ENOG4106C6R beta-lactam resistance protein FIU16_10325 ENOG4105QZ5 OriC-binding nucleoid-associated protein FIU16_10330 ENOG4105M9B inner membrane protein ydgK FIU16_10355 ENOG4108UQQ Electron transport complex FIU16_10365 ENOG4105CSM endonuclease III FIU16_10370 ENOG4105DUX Transporter FIU16_10375 ENOG4108K3A Glutathione S-transferase FIU16_10380 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FIU16_10395 ENOG410642K Lysozyme inhibitor FIU16_10405 ENOG4108XTF Outer Membrane Lipoprotein FIU16_10420 ENOG4105Y49 secretion protein, HlyD family FIU16_10425 ENOG4105DSW Fusaric acid resistance protein FIU16_10430 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FIU16_10435 ENOG4107RGM aldo keto reductase FIU16_10440 ENOG4105XZD Fe-S protein FIU16_10445 ENOG4108WUH Transcriptional regulator, TetR family FIU16_10450 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FIU16_10455 ENOG4108UYE Lactoylglutathione lyase FIU16_10465 ENOG4107QRT dEAD DEAH box helicase FIU16_10470 ENOG4105M2J Glutaredoxin FIU16_10475 ENOG4105K4H Nlp p60 protein FIU16_10480 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FIU16_10485 ENOG4105F27 Major Facilitator FIU16_10500 ENOG4105F52 Transcriptional regulator FIU16_10505 ENOG4105CZQ inner membrane transport protein YdhC FIU16_10510 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FIU16_10515 ENOG4108R6K riboflavin synthase, subunit alpha FIU16_10540 ENOG4105N0V mono-oxygenase ydhR FIU16_10545 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain FIU16_10550 ENOG4108Y7C Conserved Protein FIU16_10555 ENOG4108NWD Cytochrome FIU16_10560 ENOG4108393 oxidoreductase Fe-S subunit FIU16_10565 ENOG4105JVW FIU16_10570 ENOG4105WE2 aldehyde ferredoxin oxidoreductase FIU16_10575 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein FIU16_10580 ENOG4105RFR Protein of unknown function (DUF2767) FIU16_10585 ENOG4105CA9 Pyruvate kinase FIU16_10590 ENOG4105KMX major outer membrane lipoprotein FIU16_10595 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FIU16_10610 ENOG4105JRK feS assembly protein SufD FIU16_10615 ENOG4105C3K feS assembly ATPase SufC FIU16_10620 ENOG4105DIW FeS assembly protein SUFB FIU16_10625 ENOG4108Z4V iron-sulfur cluster assembly FIU16_10630 ENOG410671Z uncharacterized protein ydiH FIU16_10635 ENOG4105KA0 thioesterase Superfamily protein FIU16_10640 ENOG4105CQB FAD linked oxidase domain protein FIU16_10645 ENOG4105IPI Membrane FIU16_10655 ENOG4105SUA Ydil protein FIU16_10660 ENOG4105EMV Major Facilitator FIU16_10665 ENOG4105EMV Major Facilitator FIU16_10680 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FIU16_10685 ENOG4105C1G acyl-Coa dehydrogenase FIU16_10690 ENOG4105W4W Transcriptional regulator FIU16_10695 ENOG4105CV7 Electron transfer flavoprotein FIU16_10700 ENOG4105C10 Electron transfer flavoprotein FIU16_10705 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FIU16_10710 ENOG41090P5 ferredoxin-like protein FIU16_10715 ENOG4105CEY Amp-dependent synthetase and ligase FIU16_10720 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FIU16_10730 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FIU16_10735 ENOG4106EDX Hemin uptake protein FIU16_10745 ENOG4108TC0 Diguanylate phosphodiesterase FIU16_10750 ENOG4108QBX (LipO)protein FIU16_10760 ENOG4108V06 Glutathione peroxidase FIU16_10775 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FIU16_10840 ENOG4105VZ1 Replication Protein FIU16_10870 ENOG4105ED4 portal protein FIU16_10955 ENOG410685N tail fiber protein FIU16_10960 ENOG4105UZW Tail fiber assembly protein FIU16_11045 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FIU16_11050 ENOG41082NX 50s ribosomal protein l35 FIU16_11075 ENOG4108NE3 Salt-induced outer membrane protein FIU16_11080 ENOG4105DE4 1-phosphofructokinase FIU16_11085 ENOG4105P10 Uncharacterized protein ydiZ FIU16_11090 ENOG4105FGM Fructosamine kinase FIU16_11095 ENOG4107PN8 YfeABCD locus regulator FIU16_11100 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FIU16_11105 ENOG4107K5X Membrane-bound metal-dependent hydrolase FIU16_11110 ENOG4108ETY sodium dicarboxylate symporter FIU16_11130 ENOG4105CH6 catalase FIU16_11140 ENOG4105F8D glycoside hydrolase family 4 FIU16_11145 ENOG4105EZV Transcriptional regulator FIU16_11150 ENOG4105VCP PTS System FIU16_11155 ENOG4105CK1 PTS System FIU16_11160 ENOG4105VZJ PTS System FIU16_11165 ENOG4105KKI DNA-binding transcriptional activator OsmE FIU16_11175 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FIU16_11185 ENOG4108SPG Periplasmic Protein FIU16_11215 ENOG4105CGK Exodeoxyribonuclease III FIU16_11220 ENOG4108RSN SNARE associated Golgi FIU16_11225 ENOG4108KCW iron-sulfur cluster binding FIU16_11230 ENOG4108N5C SNARE associated Golgi protein-related protein FIU16_11235 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FIU16_11240 ENOG4105VNH ABC transporter solute-binding protein FIU16_11245 ENOG4105CXZ ABC transporter, permease FIU16_11250 ENOG4108VGW abc transporter atp-binding protein FIU16_11255 ENOG4107RM6 sulfurtransferase FIU16_11260 ENOG4108T9J Cdp-alcohol phosphatidyltransferase FIU16_11265 ENOG4105M6F mutator MutT protein FIU16_11270 ENOG4105MTM Protein of unknown function (DUF1496) FIU16_11275 ENOG4105D82 Glutamate dehydrogenase FIU16_11285 ENOG4105F2I Transposase FIU16_11295 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FIU16_11305 ENOG41069NU Nitroreductase FIU16_11310 ENOG4105D07 Signal peptide peptidase, SppA FIU16_11315 ENOG4105HDK L-asparaginase FIU16_11320 ENOG4108RWI nicotinamidase FIU16_11325 ENOG4108KUU Inner membrane metabolite transport protein ydjE FIU16_11330 ENOG4105E98 transcriptional regulator DeoR family FIU16_11335 ENOG4105CPC Aldo Keto reductase FIU16_11340 ENOG4107UH8 sugar kinase FIU16_11345 ENOG4105D2N Aldolase FIU16_11350 ENOG4105CPQ Dehydrogenase FIU16_11355 ENOG4107TE1 transport protein FIU16_11360 ENOG4105CPQ Dehydrogenase FIU16_11365 ENOG4105VUT cytoplasmic protein FIU16_11375 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FIU16_11380 ENOG4105DSB aldose 1-epimerase FIU16_11385 ENOG4105CV8 reductase FIU16_11390 ENOG4105GNX MltA-interacting MipA family protein FIU16_11395 ENOG4105CYN Serine protein kinase FIU16_11405 ENOG4106KTS Inner membrane protein yeaI FIU16_11410 ENOG4108KHP Diguanylate cyclase FIU16_11415 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FIU16_11430 ENOG4105R1U AraC Family Transcriptional Regulator FIU16_11435 ENOG4105DJ2 Major Facilitator Superfamily FIU16_11440 ENOG4105K78 MarR family Transcriptional regulator FIU16_11445 ENOG4105UCG Domain of unknown function (DUF333) FIU16_11450 ENOG410620I Diguanylate cyclase FIU16_11455 ENOG4106G4W FIU16_11465 ENOG4105Y3U Transglycosylase-associated protein FIU16_11470 ENOG4105D7V transposase FIU16_11475 ENOG4108RS6 transposase FIU16_11485 ENOG4105EJC lysr family transcriptional regulator FIU16_11490 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FIU16_11495 ENOG4105C94 Transporter FIU16_11500 ENOG4105DVW rieske (2Fe-2S) FIU16_11505 ENOG4105E3J oxidoreductase FIU16_11510 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FIU16_11515 ENOG4105CEY Amp-dependent synthetase and ligase FIU16_11520 ENOG4105Y4Z Outer Membrane Lipoprotein FIU16_11525 ENOG41072GX Peptidase M22 Glycoprotease FIU16_11530 ENOG4105DVT helicase FIU16_11535 ENOG4105M4H endoribonuclease L-psp FIU16_11540 ENOG4105V2F Uncharacterized protein yoac FIU16_11550 ENOG4105CRQ synthase (Component I) FIU16_11560 ENOG4105EJQ L-serine dehydratase FIU16_11565 ENOG4107XTP (EAL) domain protein FIU16_11570 ENOG4105EE5 Membrane protein terC FIU16_11575 ENOG4108EQA pts system FIU16_11580 ENOG4105ETZ PTS System FIU16_11585 ENOG4105F3R pts system mannose fructose sorbose family iid FIU16_11600 ENOG4105DHI Methyltransferase FIU16_11605 ENOG4105VEQ Cold shock protein FIU16_11610 ENOG410610J Protein of unknown function (DUF2627) FIU16_11615 ENOG4105Q3Y exported protein FIU16_11625 ENOG4105TIK FIU16_11630 ENOG4105J4Q Transcriptional regulator FIU16_11635 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU16_11645 ENOG4105CN1 protease FIU16_11655 ENOG4108ZGC gaf domain protein FIU16_11660 ENOG4105H2K paraquat-inducible protein a FIU16_11665 ENOG4105DY2 Paraquat-inducible protein b FIU16_11675 ENOG4105WT8 Protein of unknown function (DUF1480) FIU16_11680 ENOG4105UVW uncharacterized protein yebW FIU16_11685 ENOG4108R1E Serine threonine protein phosphatase 1 FIU16_11690 ENOG4105NKT exported protein FIU16_11695 ENOG4108PNC copper resistance FIU16_11700 ENOG4105FXM Copper resistance protein FIU16_11705 ENOG4105MPK DNA polymerase III subunit theta FIU16_11710 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FIU16_11715 ENOG4105UMD exodeoxyribonuclease X FIU16_11720 ENOG4105CUG Oligopeptidase b FIU16_11725 ENOG4108Q2J Inner membrane protein YebE FIU16_11730 ENOG4105RSZ secreted protein FIU16_11735 ENOG4105X2V dna damage-inducible protein FIU16_11745 ENOG4108UHU Aldolase FIU16_11750 ENOG4105C01 Dihydroxy-acid dehydratase FIU16_11755 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FIU16_11760 ENOG4106KNT transcriptional regulator FIU16_11765 ENOG4105CA9 Pyruvate kinase FIU16_11770 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FIU16_11775 ENOG4105DR5 peptidase FIU16_11780 ENOG4105NXV High-affinity zinc uptake system protein FIU16_11785 ENOG4105FDK ABC transporter FIU16_11790 ENOG4105FAV ABC, transporter FIU16_11810 ENOG4107S01 Repressor protein MetJ FIU16_11820 ENOG4105CDY transcriptional regulatory protein FIU16_11825 ENOG4108TIT dATP pyrophosphohydrolase FIU16_11835 ENOG4105D3W isochorismatase FIU16_11845 ENOG4106FE3 DNA repair FIU16_11855 ENOG4105UZW Tail fiber assembly protein FIU16_11860 ENOG4108X9F tail fiber protein FIU16_11935 ENOG4105IM0 capsid protein FIU16_11960 ENOG4105UZW Tail fiber assembly protein FIU16_11970 ENOG4106YSC FIU16_11980 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FIU16_11995 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FIU16_12030 ENOG4105D3F AraC Family Transcriptional Regulator FIU16_12055 ENOG4108MXB Protein of unknown function (DUF968) FIU16_12065 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FIU16_12070 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FIU16_12085 ENOG4105YQ0 FIU16_12095 ENOG4106050 phage regulatory protein, rha family FIU16_12100 ENOG4108S1U FIU16_12130 ENOG4105H40 FIU16_12135 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) FIU16_12140 ENOG4108R7K Metal Dependent Phosphohydrolase FIU16_12145 ENOG41077V0 CPS-53 (KpLE1) prophage FIU16_12195 ENOG4107R08 Integrase FIU16_12200 ENOG41081XQ Conserved Protein FIU16_12205 ENOG4105WJG Glutathione FIU16_12230 ENOG4108J2R molybdopterin oxidoreductase FIU16_12235 ENOG4105CUW cytochrome C-TYPE protein FIU16_12245 ENOG4106ZCM YecM protein FIU16_12260 ENOG4105W13 flagellar protein FIU16_12265 ENOG4105D7B Flagellar biosynthesis protein flha FIU16_12270 ENOG4105D00 flagellar biosynthetic protein flhB FIU16_12275 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FIU16_12280 ENOG4108VYJ response regulator receiver protein FIU16_12285 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FIU16_12290 ENOG4105BZU Histidine kinase FIU16_12295 ENOG4105C8Q Methyl-accepting chemotaxis FIU16_12300 ENOG4105C8Q Methyl-accepting chemotaxis FIU16_12305 ENOG4108V3W Chemotaxis protein, CheW FIU16_12310 ENOG4105CBS Chea signal transduction histidine kinase FIU16_12315 ENOG4105ER2 Ompa motb domain protein FIU16_12320 ENOG4107RD7 Flagellar Motor Protein, MotA FIU16_12325 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FIU16_12335 ENOG4108VA4 Universal stress protein FIU16_12345 ENOG4108K4C ec 3.1.3.12 FIU16_12350 ENOG4105CNN ABC, transporter FIU16_12355 ENOG4105C2J ABC transporter FIU16_12360 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator FIU16_12365 ENOG4108UEC Ferritin-like protein FIU16_12370 ENOG4105N4N Protein of unknown function (DUF2766) FIU16_12385 ENOG4105P23 (LipO)protein FIU16_12390 ENOG41090A1 ferritin FIU16_12395 ENOG4105VVZ metal-binding protein FIU16_12400 ENOG4105E0U tyrosine-specific transport protein FIU16_12405 ENOG4106RHG Yeca family FIU16_12425 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FIU16_12435 ENOG4105WH1 Two component transcriptional regulator luxr family FIU16_12450 ENOG4105XVG cytoplasmic protein FIU16_12455 ENOG4105VJY transcriptional regulator FIU16_12460 ENOG4105CDA abc transporter atp-binding protein FIU16_12465 ENOG4105E5Q amino acid AbC transporter FIU16_12475 ENOG4105EAB amino acid AbC transporter FIU16_12480 ENOG4108M9K flagella biosynthesis protein FliZ FIU16_12485 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU16_12490 ENOG4105I03 Flagellin FIU16_12495 ENOG4105DTS flagellar hook-associated FIU16_12500 ENOG4105MQ3 flagellar protein FliS FIU16_12510 ENOG4105E5K Alpha-amylase FIU16_12515 ENOG4108W9D (LipO)protein FIU16_12520 ENOG41066VF YeeE YedE family protein FIU16_12525 ENOG4105KSU Redox protein FIU16_12530 ENOG4108RAV Conserved protein FIU16_12535 ENOG4105D7V transposase FIU16_12540 ENOG4108RS6 transposase FIU16_12545 ENOG4108UQN AraC family transcriptional regulator FIU16_12550 ENOG4108V1U phospholipid-binding protein FIU16_12555 ENOG410814C multidrug resistance protein FIU16_12570 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FIU16_12575 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FIU16_12580 ENOG41090PJ Flagellar assembly protein FIU16_12585 ENOG4108JIR Flagellum-specific ATP synthase FIU16_12590 ENOG4105GSA Flagellar export protein flij FIU16_12595 ENOG4105WF4 Flagellar hook-length control protein FIU16_12600 ENOG4107ZI8 flagellar basal body-associated protein flil FIU16_12605 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FIU16_12610 ENOG4105DD5 Flagellar motor switch protein FIU16_12615 ENOG4105K0P flagellar biosynthesis protein FIU16_12620 ENOG4105CN7 Flagellar biosynthetic protein FliP FIU16_12625 ENOG4105VS8 Flagellar biosynthetic protein fliq FIU16_12630 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FIU16_12635 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FIU16_12650 ENOG4105YX3 cellular response to acidity FIU16_12665 ENOG4105VNZ cytoplasmic protein FIU16_12670 ENOG4105CKW Inner membrane protein yedI FIU16_12675 ENOG4105FDR Membrane FIU16_12680 ENOG41090BB DNA mismatch endonuclease (vsr) FIU16_12685 ENOG4105DVF Cytosine-specific methyltransferase FIU16_12690 ENOG4105EST Metal Dependent Phosphohydrolase FIU16_12695 ENOG4105Y0K Inner membrane protein YedR FIU16_12715 ENOG4105F9F transposase FIU16_12740 ENOG4107ZY3 Histidine kinase FIU16_12745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU16_12750 ENOG4105VT2 5-hydroxyisourate hydrolase FIU16_12765 ENOG4108MEK Metal-binding protein YodA FIU16_12800 ENOG4105BZ1 (ABC) transporter FIU16_12815 ENOG4105C0W non-ribosomal peptide synthetase FIU16_12835 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FIU16_12840 ENOG4107ZSV Receptor FIU16_12845 ENOG4105TNG K13735 adhesin invasin FIU16_12850 ENOG4105TNG K13735 adhesin invasin FIU16_12855 ENOG4105TNG K13735 adhesin invasin FIU16_12860 ENOG4105TNG K13735 adhesin invasin FIU16_12870 ENOG4105CSH Transporter FIU16_12875 ENOG4105FYV Amp nucleosidase FIU16_12880 ENOG4105CDY transcriptional regulatory protein FIU16_12890 ENOG4105UQX Mate efflux family protein FIU16_12900 ENOG4107R11 Transcriptional regulator FIU16_12905 ENOG4106P55 Transcriptional regulator FIU16_12915 ENOG4108PXI ErfK YbiS YcfS YnhG FIU16_12930 ENOG4108YZT Adenosylcobinamide kinase FIU16_12950 ENOG4108RVA ribokinase FIU16_12965 ENOG41080QX K07048 phosphotriesterase-related protein FIU16_13030 ENOG4105E5H Transposase FIU16_13035 ENOG4108YXQ IS66 Orf2 family protein FIU16_13070 ENOG4108F5E vimentin FIU16_13075 ENOG4108YIV FIU16_13100 ENOG4106H6R UPF0380 protein FIU16_13105 ENOG4105MFG Antirestriction protein FIU16_13110 ENOG4108YGG dna repair protein FIU16_13115 ENOG4106WJE Protein of unknown function (DUF987) FIU16_13120 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FIU16_13140 ENOG4105E5H Transposase FIU16_13165 ENOG4105DR8 Membrane FIU16_13170 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FIU16_13175 ENOG4105DZ1 carboxypeptidase FIU16_13180 ENOG4105CJB Exodeoxyribonuclease I FIU16_13190 ENOG4105CUC YeeE YedE family protein FIU16_13195 ENOG4105CUB amino acid FIU16_13205 ENOG4105EQ1 Transcriptional regulator FIU16_13210 ENOG4108535 NAD dependent epimerase/dehydratase family FIU16_13215 ENOG4105KRQ Addiction module toxin, Txe YoeB family FIU16_13220 ENOG4105VTW prevent-host-death family FIU16_13235 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FIU16_13245 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FIU16_13250 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FIU16_13265 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FIU16_13275 ENOG4105C6Y Udp-glucose 6-dehydrogenase FIU16_13280 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FIU16_13285 ENOG4108RYC glycosyltransferase FIU16_13295 ENOG4107XU6 Glycosyl transferase (Group 1 FIU16_13305 ENOG41066S7 Glycosyltransferase family 52 FIU16_13320 ENOG4105D2T synthase FIU16_13330 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FIU16_13335 ENOG4105DMT epimerase dehydratase FIU16_13340 ENOG4105G1A colanic acid biosynthesis protein FIU16_13345 ENOG4107T8Q Glycosyl transferase (Group 1 FIU16_13350 ENOG4105C74 pyruvyl transferase FIU16_13355 ENOG4105PSV Polysaccharide Biosynthesis Protein FIU16_13360 ENOG4105D3Q Sugar transferase FIU16_13365 ENOG4107QKV phosphomannomutase FIU16_13370 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FIU16_13375 ENOG4106CD9 glycosyl transferase group 1 FIU16_13380 ENOG4105FGF GDP-mannose mannosyl hydrolase FIU16_13385 ENOG4105C30 Nad-dependent epimerase dehydratase FIU16_13390 ENOG4105C0K Gdp-mannose 4,6-dehydratase FIU16_13395 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FIU16_13400 ENOG4105ECJ Glycosyl Transferase FIU16_13405 ENOG4108NYJ Colanic acid FIU16_13410 ENOG4107RXY Glycosyl transferase FIU16_13415 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB FIU16_13420 ENOG41090RK glycosyl transferase FIU16_13425 ENOG4105D75 Capsular exopolysaccharide family FIU16_13430 ENOG4105KJF protein tyrosine phosphatase FIU16_13435 ENOG4105DAY polysaccharide export protein FIU16_13440 ENOG4105EE5 Membrane protein terC FIU16_13445 ENOG4108GAE asmA family FIU16_13455 ENOG4105DBI uridine monophosphokinase FIU16_13460 ENOG4105BZU Histidine kinase FIU16_13465 ENOG4105D03 DNA-3-methyladenine glycosylase II FIU16_13470 ENOG4105R8A Heat shock protein FIU16_13475 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding FIU16_13480 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase FIU16_13485 ENOG4108M24 von Willebrand factor, type A FIU16_13525 ENOG4105EB3 Histidine kinase FIU16_13530 ENOG4105E3W Two component transcriptional regulator (Winged helix family FIU16_13535 ENOG4105KWI UPF0339 protein FIU16_13540 ENOG4105X54 addiction module antidote protein FIU16_13550 ENOG4105CFP Peptidase U32 FIU16_13555 ENOG41076Z6 Uncharacterized protein yegR FIU16_13570 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FIU16_13575 ENOG4105DT3 PTS system, galactitol-specific IIc component FIU16_13580 ENOG41090UW PTS System FIU16_13585 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FIU16_13605 ENOG4105EIE fructose-bisphosphate aldolase FIU16_13610 ENOG4105EAA nucleoside FIU16_13615 ENOG4108KD5 ADP-ribosylation crystallin J1 FIU16_13620 ENOG4108TFM Kinase, PfkB family FIU16_13625 ENOG4105FDP GntR family transcriptional regulator FIU16_13630 ENOG4108UQ1 hydrolase, family 25 FIU16_13635 ENOG4105DWF phosphomethylpyrimidine kinase FIU16_13655 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FIU16_13675 ENOG4105CW0 outer membrane usher protein FIU16_13680 ENOG4108MQF Chaperone FIU16_13685 ENOG41063W2 Fimbrial protein FIU16_13690 ENOG41067AK Protein of unknown function (DUF2574) FIU16_13695 ENOG4105D1F ATP-binding protein FIU16_13705 ENOG4108KDT Molybdate metabolism regulator FIU16_13710 ENOG4108KDT Molybdate metabolism regulator FIU16_13720 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FIU16_13725 ENOG4105RD5 FIU16_13730 ENOG4105DEG Vwa containing coxe family protein FIU16_13735 ENOG410903U zinc ion binding FIU16_13740 ENOG4108YCW (LipO)protein FIU16_13745 ENOG4108W15 Protein of unknown function (DUF1456) FIU16_13750 ENOG4108NEV two component transcriptional regulator, LytTR family FIU16_13755 ENOG4108HRK Histidine kinase FIU16_13760 ENOG4108XDN Transcriptional regulator FIU16_13770 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FIU16_13775 ENOG4108IJ8 ABC transporter FIU16_13780 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FIU16_13785 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FIU16_13790 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FIU16_13795 ENOG4105CXG d-lactate dehydrogenase FIU16_13800 ENOG41061WM D-Alanyl-D-Alanine FIU16_13805 ENOG41069YE inner membrane protein yohC FIU16_13810 ENOG4105KHU inner membrane protein YohD FIU16_13815 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FIU16_13820 ENOG4105ETP RND efflux system, outer membrane lipoprotein FIU16_13830 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FIU16_13840 ENOG41067MG lrgb family FIU16_13850 ENOG4107GZ4 SanA protein FIU16_13855 ENOG4105Y9N Membrane FIU16_13860 ENOG4105BZ8 glutamate synthase FIU16_13865 ENOG4107SJI Dehydrogenase FIU16_13870 ENOG4108HWV )-transporter FIU16_13875 ENOG4105C2J ABC transporter FIU16_13880 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FIU16_13885 ENOG41060NJ transcriptional regulator FIU16_13890 ENOG4105DHF Membrane FIU16_13900 ENOG4105C4W S-formylglutathione hydrolase FIU16_13905 ENOG4105D05 Receptor FIU16_13910 ENOG4108IQI permease FIU16_13915 ENOG4105DUM transcriptional regulator, lysR family FIU16_13920 ENOG4105HMI Membrane FIU16_13930 ENOG4105DD7 kinase (PfkB family FIU16_13935 ENOG4105D9N nucleoside FIU16_13945 ENOG4108Y4K DNA-binding transcriptional activator FIU16_13950 ENOG4105D9N nucleoside FIU16_13955 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FIU16_13960 ENOG4105DD7 kinase (PfkB family FIU16_13965 ENOG4105DM4 PTS System FIU16_13970 ENOG4105DE4 1-phosphofructokinase FIU16_13975 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FIU16_13980 ENOG4105S8Q sugar efflux transporter FIU16_13985 ENOG4105KRS Proteinase inhibitor FIU16_13995 ENOG4105DEI Mannitol dehydrogenase FIU16_14000 ENOG4105CKI cobalamin synthesis protein FIU16_14005 ENOG41076MN Phosphoesterase, PA-phosphatase related FIU16_14010 ENOG4107TT5 NLP P60 protein FIU16_14015 ENOG4105CXC rtn protein FIU16_14020 ENOG4105E43 Extracellular solute-binding protein, family 5 FIU16_14025 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FIU16_14030 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FIU16_14035 ENOG4108JQ5 ABC transporter FIU16_14040 ENOG4105HG6 FIU16_14045 ENOG4105C2C drug resistance transporter, Bcr CflA FIU16_14050 ENOG4105I08 Pseudouridine synthase FIU16_14055 ENOG4105CFI type iii restriction protein res subunit FIU16_14075 ENOG4105E68 Sulfatase FIU16_14090 ENOG4105WH1 Two component transcriptional regulator luxr family FIU16_14095 ENOG4105KWW Biogenesis protein FIU16_14100 ENOG4107QX9 Thiol disulfide interChange protein FIU16_14105 ENOG4105DA4 cytochrome c-type biogenesis protein FIU16_14115 ENOG4105X3C heme exporter protein FIU16_14120 ENOG41060IM Heme exporter protein FIU16_14125 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FIU16_14130 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FIU16_14135 ENOG4105CUW cytochrome C-TYPE protein FIU16_14140 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FIU16_14145 ENOG4105GXZ Ferredoxin-type protein NapH FIU16_14150 ENOG4108BGM Quinol dehydrogenase periplasmic component FIU16_14160 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FIU16_14165 ENOG4108ZNS ferredoxin-type protein NapF FIU16_14180 ENOG4105IBP Cyclic peptide transporter FIU16_14185 ENOG4105CF1 Alkylated DNA repair protein FIU16_14190 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FIU16_14195 ENOG4105CJ2 (LipO)protein FIU16_14200 ENOG4105FCK Membrane FIU16_14205 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FIU16_14210 ENOG41068CG regulatoR FIU16_14215 ENOG4105BZU Histidine kinase FIU16_14220 ENOG4105EDV vault protein FIU16_14225 ENOG41081SK signal peptide protein FIU16_14230 ENOG4107S52 alpha-2-macroglobulin domain protein FIU16_14235 ENOG4108QJJ Protein of unknown function (DUF1175) FIU16_14240 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) FIU16_14245 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU16_14255 ENOG4107GHC outer membrane autotransporter FIU16_14260 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU16_14265 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU16_14270 ENOG4105XPH Ferredoxin FIU16_14275 ENOG4105FQR PH-inducible protein involved in stress response FIU16_14280 ENOG4105F2I Transposase FIU16_14290 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FIU16_14295 ENOG4105CXY transporter FIU16_14300 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FIU16_14310 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FIU16_14315 ENOG4105DNE Transposase FIU16_14320 ENOG4105CNV Aldolase FIU16_14330 ENOG4108UII YfaZ family FIU16_14380 ENOG4106GZG polymyxin resistance protein B FIU16_14385 ENOG4105CEY Amp-dependent synthetase and ligase FIU16_14395 ENOG4108IPT Naphthoate synthase FIU16_14410 ENOG4105E4F Isochorismate synthase FIU16_14415 ENOG4105TNS Conserved Protein FIU16_14420 ENOG4107YB6 acetyltransferase, (GNAT) family FIU16_14440 ENOG4105GDX Domain of unknown function (DUF1877) FIU16_14450 ENOG4105C8S subunit m FIU16_14455 ENOG4105D65 subunit l FIU16_14460 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FIU16_14465 ENOG4107UFS subunit j FIU16_14470 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FIU16_14480 ENOG4108IEH NADH dehydrogenase subunit g FIU16_14485 ENOG4107QIZ NADH dehydrogenase FIU16_14490 ENOG4105GKE subunit e FIU16_14510 ENOG4107NQ8 LysR family Transcriptional regulator FIU16_14515 ENOG4105CHM Aminotransferase FIU16_14525 ENOG4107QWE )-transporter FIU16_14530 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FIU16_14545 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FIU16_14550 ENOG4105C6K Malic enzyme FIU16_14555 ENOG4105CSX c4-dicarboxylate anaerobic carrier FIU16_14560 ENOG4105PTV Nudix Hydrolase FIU16_14565 ENOG4108RE9 Phosphodiesterase FIU16_14570 ENOG4108SHQ Glutathione S-transferase FIU16_14575 ENOG4105CYM Glutathione S-transferase FIU16_14580 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase FIU16_14585 ENOG4105ECP epimerase FIU16_14590 ENOG4105DNE Transposase FIU16_14595 ENOG4108JEH abc transporter atp-binding protein FIU16_14600 ENOG4106YG3 ABC transporter FIU16_14605 ENOG4105DSP amino acid AbC transporter FIU16_14610 ENOG4105E89 ABC transporter FIU16_14615 ENOG4105E89 ABC transporter FIU16_14620 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FIU16_14625 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FIU16_14630 ENOG4105E96 Colicin v production protein FIU16_14635 ENOG4108S3P Sporulation domain protein FIU16_14640 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FIU16_14650 ENOG4105DQR SNARE associated Golgi FIU16_14660 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FIU16_14670 ENOG4106WZ1 flagella biosynthesis regulator FIU16_14675 ENOG4105F9N Major Facilitator Superfamily FIU16_14680 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FIU16_14685 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FIU16_14690 ENOG4105MH2 YfcL protein FIU16_14695 ENOG4108BPE -transporting atpase FIU16_14700 ENOG4105EJ9 Membrane FIU16_14740 ENOG4105US4 fimbrial-like protein yfcP FIU16_14745 ENOG4105UGQ Fimbrial FIU16_14755 ENOG4105NEV Fimbrial FIU16_14760 ENOG4108FZ9 Chaperone FIU16_14765 ENOG4106PG1 outer membrane usher protein FIU16_14775 ENOG4108BY2 phosphohistidine phosphatase FIU16_14790 ENOG4105KZW UPF0381 protein FIU16_14795 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FIU16_14805 ENOG410903C (LipO)protein FIU16_14810 ENOG4105S64 Formate nitrite transporter FIU16_14820 ENOG4105DFP Integrase FIU16_14915 ENOG4108N0N Phage Terminase Large Subunit FIU16_15000 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision FIU16_15005 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FIU16_15010 ENOG4105D7K pfkb domain protein FIU16_15015 ENOG4108HKT sucrose-6-phosphate hydrolase FIU16_15020 ENOG4106NDP Transcriptional regulator FIU16_15035 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU16_15040 ENOG4105CW7 secretion protein, HlyD family FIU16_15045 ENOG4108WQH regulatoR FIU16_15050 ENOG4105BZU Histidine kinase FIU16_15055 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FIU16_15060 ENOG4108N2Y auxin Efflux FIU16_15065 ENOG4105CFN oxalyl-CoA decarboxylase FIU16_15075 ENOG4108V08 YfdX protein FIU16_15085 ENOG4105W9M Membrane FIU16_15090 ENOG4105D1S lipid A biosynthesis FIU16_15100 ENOG4105CHM Aminotransferase FIU16_15105 ENOG4108HRK Histidine kinase FIU16_15110 ENOG4105DY9 regulatoR FIU16_15120 ENOG4105F2I Transposase FIU16_15130 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FIU16_15135 ENOG4105CN9 Peptidase m42 family protein FIU16_15140 ENOG4105DC7 peptidase M24 FIU16_15145 ENOG410863U PTS System FIU16_15150 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FIU16_15165 ENOG4109076 Conserved Protein FIU16_15175 ENOG4105D9N nucleoside FIU16_15180 ENOG4108KMM Diguanylate cyclase FIU16_15195 ENOG4105HZG regulatoR FIU16_15200 ENOG4105GXM Putative transcription regulator (DUF1323) FIU16_15235 ENOG4105CN8 Transcriptional regulator FIU16_15245 ENOG4105EAA nucleoside FIU16_15250 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FIU16_15255 ENOG4108NFH Sugar hydrolase FIU16_15260 ENOG4108M0I Transcriptional regulator FIU16_15265 ENOG4105DHU Bile acid FIU16_15270 ENOG4105VRT cytoplasmic protein FIU16_15290 ENOG4105C6T cysteine synthase FIU16_15295 ENOG4105KZ7 phosphocarrier protein hpr FIU16_15300 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FIU16_15305 ENOG4105C5Y PTS System FIU16_15315 ENOG4105M0Y FIU16_15320 ENOG4105C6T cysteine synthase FIU16_15325 ENOG4108IJ6 ABC transporter FIU16_15330 ENOG4105ECW sulfate abc transporter FIU16_15335 ENOG4108I5D sulfate abc transporter FIU16_15340 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FIU16_15345 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FIU16_15360 ENOG4105C5Y PTS System FIU16_15365 ENOG4107S1E Beta-lactamase FIU16_15370 ENOG4105EZR dyp-type peroxidase family protein FIU16_15375 ENOG4105E7K (LipO)protein FIU16_15380 ENOG4105QZU Inner membrane protein YfeZ FIU16_15385 ENOG4108R6G acetyltransferase FIU16_15390 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FIU16_15400 ENOG4108K3Z AraC family transcriptional regulator FIU16_15405 ENOG4108X49 Ethanolamine utilization protein EutK FIU16_15410 ENOG4106D67 ethanolamine utilization protein FIU16_15420 ENOG4105CPD ethanolamine ammonia-lyase FIU16_15425 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FIU16_15430 ENOG4105ENY Ethanolamine utilization protein eutH FIU16_15435 ENOG4105C0A alcohol dehydrogenase FIU16_15440 ENOG4107RWI ethanolamine utilization protein eutJ FIU16_15445 ENOG4108EKI Dehydrogenase FIU16_15450 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FIU16_15455 ENOG4105KNY Microcompartments protein FIU16_15460 ENOG4107WUY phosphate acetyltransferase FIU16_15465 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FIU16_15470 ENOG4105NDK ethanolamine utilization protein FIU16_15475 ENOG4106S4J ethanolamine utilization protein EutP FIU16_15480 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FIU16_15485 ENOG4105C6K Malic enzyme FIU16_15490 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FIU16_15495 ENOG4105CV1 Transketolase (EC 2.2.1.1) FIU16_15500 ENOG4108PVD exported protein FIU16_15510 ENOG4105BZ8 glutamate synthase FIU16_15515 ENOG4105BZU Histidine kinase FIU16_15520 ENOG4105BZS acriflavin resistance protein FIU16_15530 ENOG4105KUZ arsenate reductase FIU16_15545 ENOG4106KED esterase YpfH FIU16_15550 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) FIU16_15555 ENOG4105CGZ zinc metallopeptidase FIU16_15560 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FIU16_15575 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FIU16_15585 ENOG4105RH4 Glycine cleavage system transcriptional repressor FIU16_15590 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FIU16_15595 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FIU16_15600 ENOG4108JPZ Monovalent cation H antiporter subunit D FIU16_15615 ENOG4107WQX hydrogenase 4 membrane subunit FIU16_15620 ENOG4108JPZ Monovalent cation H antiporter subunit D FIU16_15625 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FIU16_15635 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FIU16_15640 ENOG4105I6X formate hydrogenlyase maturation FIU16_15645 ENOG4108JUA Transcriptional regulator FIU16_15650 ENOG4105TMB Formate nitrite transporter FIU16_15655 ENOG4105TMB Formate nitrite transporter FIU16_15660 ENOG4105C02 permease FIU16_15665 ENOG4105ERG peptidase m48, ste24p FIU16_15670 ENOG4105K89 arsenate reductase FIU16_15680 ENOG4105C2W permease FIU16_15695 ENOG4108V3E phosphoribosylglycinamide formyltransferase FIU16_15700 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FIU16_15705 ENOG4105C9X ppx gppa phosphatase FIU16_15710 ENOG4105BZU Histidine kinase FIU16_15715 ENOG41062G3 Protein of unknown function (DUF2633) FIU16_15720 ENOG4108ZMA Outer membrane lipoprotein FIU16_15725 ENOG41066DY Membrane FIU16_15735 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FIU16_15745 ENOG4105VPD cellular component movement FIU16_15760 ENOG4105N21 Membrane FIU16_15790 ENOG4108JQB penicillin-binding protein 1C FIU16_15795 ENOG4105DN3 alpha-2-macroglobulin domain protein FIU16_15800 ENOG4105KHC sulfurtransferase FIU16_15805 ENOG4105YYA enhanced serine sensitivity protein SseB FIU16_15815 ENOG4105WVQ Fe-S assembly protein IscX FIU16_15820 ENOG4108ZIT Ferredoxin, 2FE-2S FIU16_15840 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FIU16_15865 ENOG4107XM9 (LipO)protein FIU16_15870 ENOG4108MN2 Stationary phase inducible protein CsiE FIU16_15875 ENOG4105D8G Major Facilitator superfamily FIU16_15880 ENOG4108W5M transcriptional regulator FIU16_15885 ENOG4105FUY alpha subunit FIU16_15910 ENOG4108SB3 DoxX Family FIU16_15915 ENOG4108ZKT aldose 1-epimerase FIU16_15920 ENOG4105CPQ Dehydrogenase FIU16_15925 ENOG4105CNN ABC, transporter FIU16_15930 ENOG4108F37 ATP-binding component of a transport system FIU16_15935 ENOG4105FCA ABC transporter periplasmic-binding protein YphF FIU16_15940 ENOG4107HQ7 repeat protein FIU16_15945 ENOG4108NZE NAGC-like transcriptional regulator FIU16_15955 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FIU16_15960 ENOG4108YZA Nitrogen regulatory protein pii FIU16_15965 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FIU16_15970 ENOG4108SKK alpha helix protein FIU16_15975 ENOG4107WP9 Histidine kinase FIU16_15980 ENOG4107QIK phosphoribosylformylglycinamidine synthase FIU16_15990 ENOG4108Z6B deaminase FIU16_15995 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FIU16_16000 ENOG4106G6Q Transcriptional regulator FIU16_16005 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FIU16_16020 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FIU16_16040 ENOG4105C3F Signal peptidase i FIU16_16050 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FIU16_16055 ENOG4105VQK sigma E regulatory protein, MucB RseB FIU16_16060 ENOG41069PW sigma-e factor negative regulatory protein FIU16_16065 ENOG4105EMN RNA polymerase sigma factor FIU16_16075 ENOG4108IYU L-aspartate oxidase FIU16_16085 ENOG4105C1J atp-dependent rna helicase FIU16_16090 ENOG41090KR LysR family transcriptional Regulator FIU16_16110 ENOG4105EIB trna rrna methyltransferase FIU16_16115 ENOG4105K63 Thioredoxin FIU16_16120 ENOG4106IUH DTW domain containing protein FIU16_16125 ENOG4105CD5 CoA-binding domain protein FIU16_16130 ENOG4105JIM Phosphatidylserine synthase FIU16_16135 ENOG4105T42 (LipO)protein FIU16_16140 ENOG4105CSH Transporter FIU16_16165 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FIU16_16170 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FIU16_16175 ENOG4105C34 Pseudouridine synthase FIU16_16180 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FIU16_16185 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FIU16_16195 ENOG4105CQC Prephenate dehydratase FIU16_16200 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FIU16_16205 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FIU16_16210 ENOG4105QP9 Protein of unknown function (DUF2799) FIU16_16215 ENOG4108WS1 FIU16_16220 ENOG4108KHX Diguanylate cyclase FIU16_16225 ENOG41090EK ompa motb domain protein FIU16_16250 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FIU16_16255 ENOG4106KVJ cytochrome C assembly protein FIU16_16260 ENOG4108JU6 CBS domain protein FIU16_16275 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FIU16_16280 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FIU16_16285 ENOG4105VDB UPF0125 protein FIU16_16290 ENOG4108Z1B Cyclase dehydrase FIU16_16305 ENOG4105DFP Integrase FIU16_16335 ENOG410679B prophage CP4-57 regulatory protein alpA FIU16_16340 ENOG4108MXD gtp-binding protein FIU16_16350 ENOG4108MGN ATP-binding component of a transport system FIU16_16385 ENOG4105E54 alpha-amylase FIU16_16395 ENOG4105D5U fad dependent oxidoreductase FIU16_16400 ENOG4105C26 Dehydrogenase FIU16_16405 ENOG4108JPW Aminotransferase FIU16_16410 ENOG4105C85 amino acid FIU16_16415 ENOG4108PVQ transcriptional regulator FIU16_16420 ENOG4109066 lysm domain bon superfamily protein FIU16_16425 ENOG4105VPI YqaE family transport protein FIU16_16430 ENOG41080HT Transcriptional regulator, arsr family FIU16_16435 ENOG4108V62 Rhodanese domain protein FIU16_16440 ENOG4108X73 DNA- binding protein FIU16_16445 ENOG4108RNS Exports L-alanine (By similarity) FIU16_16450 ENOG4108WMJ Protein of unknown function (DUF2002) FIU16_16455 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FIU16_16460 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FIU16_16470 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU16_16475 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FIU16_16480 ENOG4108IJ7 Glycine betaine FIU16_16485 ENOG4108HQS Glycine betaine FIU16_16490 ENOG4105GIJ Glycine betaine FIU16_16500 ENOG4108UMN azlc family FIU16_16505 ENOG4105ZED uncharacterized protein ygaH FIU16_16510 ENOG4105NTK Transcriptional repressor Mpra FIU16_16515 ENOG4105CW7 secretion protein, HlyD family FIU16_16520 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU16_16535 ENOG4105W39 Membrane FIU16_16540 ENOG4107VXZ Hydrolase FIU16_16570 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FIU16_16590 ENOG4107TH8 cina domain protein FIU16_16595 ENOG4105CVE Lytic murein transglycosylase FIU16_16600 ENOG410787A Pts system, glucitol sorbitol-specific FIU16_16605 ENOG4105DZY Pts system, glucitol sorbitol-specific FIU16_16610 ENOG4105VI0 Pts system, glucitol sorbitol-specific FIU16_16615 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FIU16_16620 ENOG4105J92 DNA-binding transcriptional activator GutM FIU16_16625 ENOG410804X Transcriptional regulator FIU16_16630 ENOG4105C2X Arabinose 5-phosphate isomerase FIU16_16650 ENOG4105C8H hydrogenase maturation protein Hypf FIU16_16655 ENOG4108RC0 Electron transport protein FIU16_16660 ENOG4105DDV Transcriptional regulator (LacI family FIU16_16665 ENOG4105C5Y PTS System FIU16_16670 ENOG4105CS2 ec 3.2.1.21 FIU16_16685 ENOG4108Z3N Transcriptional regulator FIU16_16695 ENOG4108MG9 hydrogenase 3 maturation protease FIU16_16700 ENOG4105I6X formate hydrogenlyase maturation FIU16_16705 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FIU16_16710 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FIU16_16715 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FIU16_16720 ENOG4107TDF Formate hydrogenlyase subunit 4 FIU16_16725 ENOG4107R30 NADH dehydrogenase FIU16_16730 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FIU16_16735 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FIU16_16745 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FIU16_16750 ENOG4107RSS Hydrogenase accessory protein HypB FIU16_16755 ENOG41083WG hydrogenase assembly chaperone FIU16_16760 ENOG4105CQS hydrogenase expression formation protein HypD FIU16_16765 ENOG4105C45 hydrogenase expression formation protein (HypE) FIU16_16770 ENOG4108JUA Transcriptional regulator FIU16_16775 ENOG4105VXR cytoplasmic protein FIU16_16790 ENOG4105MEW serine threonine protein phosphatase FIU16_16795 ENOG4105MVE transcriptional regulator FIU16_16800 ENOG4105ZXK Dehydrogenase FIU16_16805 ENOG4105G63 Type III effector Hrp-dependent FIU16_16810 ENOG4105FB2 class II Aldolase FIU16_16815 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FIU16_16820 ENOG4105C6Z Gluconate FIU16_16825 ENOG4105KZM cytoplasmic protein FIU16_16830 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FIU16_16835 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FIU16_16845 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU16_16850 ENOG4108K5P (LipO)protein FIU16_16885 ENOG4105N0Z inner membrane protein ygbE FIU16_16905 ENOG4108MXK alkaline phosphatase isozyme conversion FIU16_16910 ENOG4105PWE CRISPR-associated protein cas2 FIU16_16915 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FIU16_16925 ENOG4108VWQ crispr-associated protein FIU16_16930 ENOG41060M0 Crispr-associated protein, cse4 family FIU16_16940 ENOG4105CYR Crispr-associated protein, cse1 family FIU16_16945 ENOG4105DTT CRISPR-associated helicase, cas3 FIU16_16950 ENOG4108SER Transposase FIU16_16955 ENOG4107635 Hok Gef family protein FIU16_16980 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FIU16_16985 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FIU16_16990 ENOG4105WQV ferredoxin-like protein FIU16_16995 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FIU16_17000 ENOG4105YBM electron transfer flavoprotein subunit ygcQ FIU16_17005 ENOG4106IKH Electron transfer flavoprotein FIU16_17010 ENOG4105C54 Major Facilitator superfamily FIU16_17015 ENOG4107R3A FAD linked oxidase domain protein FIU16_17020 ENOG4105CHR reductase FIU16_17025 ENOG4108ITV Inner membrane protein yqcE FIU16_17030 ENOG4108CWB sugar kinase ygcE FIU16_17035 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FIU16_17060 ENOG4105DXN mazG family FIU16_17065 ENOG4105MZG transcriptional modulator of maze toxin, mazf FIU16_17070 ENOG4106A2Z transcriptional regulator antitoxin, MazE FIU16_17075 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FIU16_17085 ENOG4105BZU Histidine kinase FIU16_17090 ENOG4105EQX glucarate dehydratase FIU16_17095 ENOG4105EQX glucarate dehydratase FIU16_17105 ENOG4105DJB Major Facilitator Superfamily FIU16_17110 ENOG4105QDK Flavodoxin FIU16_17120 ENOG4105WP7 tRNA pseudouridine synthase C FIU16_17135 ENOG4105EWT decarboxylase family FIU16_17140 ENOG4105C44 Serine transporter FIU16_17145 ENOG4105EJQ L-serine dehydratase FIU16_17155 ENOG4105C0A alcohol dehydrogenase FIU16_17160 ENOG4107W7X Aldolase FIU16_17165 ENOG4105EDR glucose galactose transporter FIU16_17175 ENOG4105CMG Carbohydrate kinase FIU16_17185 ENOG4107EDW L-fucose operon activator FIU16_17195 ENOG4105M08 Membrane FIU16_17200 ENOG4105ETT transcriptional Regulator, LysR family FIU16_17205 ENOG4105M5B (LipO)protein FIU16_17210 ENOG4105C9B Cysteine desulfurase FIU16_17215 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FIU16_17220 ENOG4105CUZ uba thif-type nad fad binding protein FIU16_17225 ENOG4105CA3 membrane-bound lytic murein transglycosylase FIU16_17245 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU16_17250 ENOG4107QZM n-acetylglutamate synthase FIU16_17255 ENOG4107QYX exodeoxyribonuclease v alpha FIU16_17260 ENOG4107QKA exodeoxyribonuclease V beta FIU16_17265 ENOG4107QXK peptidase FIU16_17270 ENOG4105DSY exodeoxyribonuclease V, gamma FIU16_17275 ENOG4105RVB Prepilin peptidase dependent protein c FIU16_17280 ENOG4105SEN Protein of unknown function (DUF2509) FIU16_17285 ENOG4105JCS prepilin peptidase dependent protein FIU16_17290 ENOG4105IPU prepilin peptidase dependent protein A FIU16_17305 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FIU16_17325 ENOG4105EE5 Membrane protein terC FIU16_17330 ENOG4105SUV lipoprotein YgdR FIU16_17335 ENOG4105CPC Aldo Keto reductase FIU16_17355 ENOG41060NJ transcriptional regulator FIU16_17360 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FIU16_17365 ENOG4105RQF LysR family Transcriptional regulator FIU16_17375 ENOG4107QNK )-transporter FIU16_17380 ENOG4105CHR reductase FIU16_17390 ENOG4105CHU acetyl-coa acetyltransferase FIU16_17395 ENOG4108MHD transport protein FIU16_17400 ENOG4105ISV protein with bipartite regulator domain FIU16_17405 ENOG4108TC1 Transcriptional regulator FIU16_17410 ENOG4105FV3 FIU16_17435 ENOG4108YAB Invasion protein FIU16_17475 ENOG4108RBT type iii secretion FIU16_17490 ENOG4108RC9 Type III secretion system protein FIU16_17505 ENOG4108M6W surface presentation of antigens protein SpaS FIU16_17515 ENOG4108TN6 type iii secretion FIU16_17525 ENOG41075IY surface presentation of antigens protein SpaP FIU16_17540 ENOG4108T88 FIU16_17550 ENOG4108K5P (LipO)protein FIU16_17555 ENOG4105C7W Xanthine dehydrogenase FIU16_17560 ENOG4108HR6 Dehydrogenase FIU16_17565 ENOG4108UTP (2Fe-2S)-binding domain protein FIU16_17570 ENOG4108JUB Transcriptional regulator FIU16_17575 ENOG4105IW6 Carbamoyltransferase FIU16_17580 ENOG4107RCH Diaminopropionate ammonia-lyase FIU16_17585 ENOG4107S4Y M20 DapE family protein YgeY FIU16_17595 ENOG4105C5B carbamate kinase FIU16_17600 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FIU16_17605 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC FIU16_17610 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase FIU16_17615 ENOG4105BZ8 glutamate synthase FIU16_17620 ENOG4107UUR Chlorohydrolase aminohydrolase FIU16_17625 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase FIU16_17630 ENOG4105C7W Xanthine dehydrogenase FIU16_17635 ENOG4105C2W permease FIU16_17640 ENOG4107QUY Guanine deaminase FIU16_17645 ENOG4105C7N Xanthine uracil vitamin C permease FIU16_17650 ENOG4108R8B oxidoreductase Fe-S subunit FIU16_17655 ENOG4105BZ8 glutamate synthase FIU16_17660 ENOG4105C2W permease FIU16_17680 ENOG4105CRK lysyL-tRNA synthetase FIU16_17690 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FIU16_17695 ENOG4105T95 Thiol disulfide interChange protein FIU16_17700 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FIU16_17705 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FIU16_17710 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FIU16_17715 ENOG4105Y75 tpr repeat protein FIU16_17725 ENOG4108UT2 hemolysin iii FIU16_17735 ENOG4105CS2 ec 3.2.1.21 FIU16_17740 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FIU16_17765 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FIU16_17770 ENOG4105D0A hydroxylase FIU16_17775 ENOG4107RAQ aminopeptidase FIU16_17795 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FIU16_17810 ENOG4108JQ1 Dehydrogenase FIU16_17830 ENOG4105DJT lAO AO transport system ATPase FIU16_17835 ENOG4108M7F enoyl-CoA hydratase isomerase FIU16_17840 ENOG4105CYC Transferase FIU16_17845 ENOG4105DEQ transcriptional regulator FIU16_17850 ENOG4105MPN Membrane FIU16_17855 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FIU16_17860 ENOG4105D64 Mechanosensitive ion channel FIU16_17865 ENOG4105D2N Aldolase FIU16_17895 ENOG4108JJB ABC transporter FIU16_17900 ENOG4108JJB ABC transporter FIU16_17905 ENOG4107Z1W Fructose transport system kinase FIU16_17910 ENOG4108R4K DNA-binding, transcriptional regulator FIU16_17915 ENOG4108Q8A Fructose-1,6-bisphosphatase FIU16_17920 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FIU16_17925 ENOG4105CTS PTS system mannitol-specific FIU16_17930 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia FIU16_17935 ENOG4105CV1 Transketolase (EC 2.2.1.1) FIU16_17940 ENOG4108K0D peptidase, M48 FIU16_17955 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FIU16_17970 ENOG4107QNK )-transporter FIU16_17980 ENOG4105RWS endonuclease I FIU16_17985 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FIU16_17990 ENOG4105D7Z glutathione synthase FIU16_18005 ENOG4105CZX twitching motility protein FIU16_18010 ENOG4105DFA alanine racemase domain protein FIU16_18015 ENOG4108VIA integral membrane protein FIU16_18025 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FIU16_18030 ENOG4105CSA Coproporphyrinogen iii oxidase FIU16_18035 ENOG4106MH3 alpha helix chain FIU16_18040 ENOG4105HDK L-asparaginase FIU16_18045 ENOG4105K33 Periplasmic Protein FIU16_18050 ENOG41090ED Protein with unknown function (DUF469) FIU16_18060 ENOG4105CEN a g-specific adenine glycosylase FIU16_18075 ENOG4105EAA nucleoside FIU16_18080 ENOG4105CXN decarboxylase FIU16_18085 ENOG4108UQV Membrane FIU16_18125 ENOG4105C0D helicase FIU16_18140 ENOG4107QMH DNA methylase FIU16_18155 ENOG4105PBD transposase, IS3 IS911 family protein FIU16_18160 ENOG4105F9F transposase FIU16_18180 ENOG4105EKQ RNA-directed DNA polymerase FIU16_18190 ENOG4105I1J Autotransporter FIU16_18210 ENOG4108YXQ IS66 Orf2 family protein FIU16_18215 ENOG4105E5H Transposase FIU16_18220 ENOG4105F2I Transposase FIU16_18230 ENOG4105DQ6 Transposase FIU16_18285 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FIU16_18330 ENOG4105CS6 Rhs element vgr protein FIU16_18475 ENOG4105KF5 hemolysin expression-modulating protein FIU16_18515 ENOG4105F4K antigen 43 FIU16_18520 ENOG4108PZQ Inner membrane protein YeeR FIU16_18540 ENOG4106H6R UPF0380 protein FIU16_18550 ENOG4105MFG Antirestriction protein FIU16_18555 ENOG4108YGG dna repair protein FIU16_18560 ENOG4106WJE Protein of unknown function (DUF987) FIU16_18565 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FIU16_18590 ENOG4105U1E general secretion pathway protein M FIU16_18610 ENOG4105X5Z General secretion pathway protein I FIU16_18620 ENOG4108VAU general secretion pathway protein G FIU16_18625 ENOG4105D7Q type ii secretion system FIU16_18630 ENOG4107QHF type ii secretion system protein e FIU16_18645 ENOG410765S (LipO)protein FIU16_18660 ENOG4105DAA L-lactate FIU16_18665 ENOG4107QP3 malate synthase g FIU16_18670 ENOG4108ZJF Glcg protein FIU16_18675 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FIU16_18680 ENOG4105EU8 FAD linked oxidase domain protein FIU16_18685 ENOG4105CQB FAD linked oxidase domain protein FIU16_18690 ENOG4108KWP DNA-binding transcriptional regulator GlcC FIU16_18700 ENOG4107RCI amp-dependent synthetase and ligase FIU16_18710 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FIU16_18715 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FIU16_18725 ENOG4108M8S permease YjgP YjgQ family protein FIU16_18730 ENOG4108UUE Transcriptional regulator FIU16_18740 ENOG4108S55 polysaccharide biosynthesis protein FIU16_18745 ENOG4106FPV ATP-binding protein YghR FIU16_18750 ENOG4108NDC ATP-binding protein yghS FIU16_18755 ENOG4108GH0 ATP-binding protein yghT FIU16_18760 ENOG4105CJ3 phosphate transporter FIU16_18765 ENOG4106032 Glutathionylspermidine synthase FIU16_18770 ENOG4105CYM Glutathione S-transferase FIU16_18785 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FIU16_18790 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FIU16_18795 ENOG4108WGS hydrogenase 2-specific chaperone FIU16_18800 ENOG4108USZ hydrogenase FIU16_18805 ENOG4105DPX Hydrogenase, large subunit FIU16_18810 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FIU16_18815 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FIU16_18820 ENOG4105E3S small subunit FIU16_18825 ENOG410900S Protein of unknown function (DUF2623) FIU16_18835 ENOG4105CPC Aldo Keto reductase FIU16_18845 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FIU16_18850 ENOG4108ZZF transport protein (ExbD) FIU16_18855 ENOG4105CWK Biopolymer transport protein, ExbB FIU16_18860 ENOG4105C28 cystathionine FIU16_18865 ENOG4108K81 inner membrane protein YghB FIU16_18870 ENOG4105CF7 AraC family transcriptional regulator FIU16_18875 ENOG4108I6A alcohol dehydrogenase FIU16_18880 ENOG4105CV8 reductase FIU16_18885 ENOG4105ZKC Conserved Protein FIU16_18895 ENOG4105CCT upf0313 protein FIU16_18900 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FIU16_18905 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FIU16_18910 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU16_18915 ENOG4105F4I Transcriptional regulator FIU16_18920 ENOG4105H4F exported protein FIU16_18925 ENOG4105XJC Two component transcriptional regulator (Winged helix family FIU16_18930 ENOG4105DHQ Histidine kinase FIU16_18935 ENOG4107DEU Inner membrane protein YgiZ FIU16_18940 ENOG4105NF4 modulator of drug activity FIU16_18945 ENOG4105VRH Antibiotic biosynthesis monooxygenase FIU16_18950 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU16_18955 ENOG4105IPS esterase FIU16_18960 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FIU16_18965 ENOG4108SX3 cytoplasmic protein FIU16_18970 ENOG41087AY ADP-Ribose pyrophosphatase FIU16_18975 ENOG4105DFG type I secretion outer membrane protein FIU16_18985 ENOG4106032 Glutathionylspermidine synthase FIU16_18990 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FIU16_19005 ENOG4105W0Z cytoplasmic protein FIU16_19010 ENOG4105H8W Fimbrial protein FIU16_19020 ENOG4108TTM chaperone FIU16_19025 ENOG4108MY7 Fimbrial FIU16_19035 ENOG4105PV3 Inner membrane protein yqiJ FIU16_19040 ENOG4107S78 Band 7 protein FIU16_19065 ENOG4105I7R Adenylate cyclase FIU16_19070 ENOG4106MWK domain protein FIU16_19085 ENOG4107ZVW dihydroneopterin aldolase FIU16_19095 ENOG4105EJC lysr family transcriptional regulator FIU16_19100 ENOG4106DSS Tartrate dehydratase subunit alpha FIU16_19105 ENOG4107GFK fumarate FIU16_19110 ENOG4107QPK )-transporter FIU16_19120 ENOG4105VCC 30S ribosomal protein S21 FIU16_19125 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FIU16_19130 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU16_19145 ENOG4105Q26 Siderophore-interacting protein FIU16_19150 ENOG4105NTW Transcriptional regulator FIU16_19155 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FIU16_19165 ENOG4108Y51 tRNA-binding protein FIU16_19170 ENOG4105CQ4 Transcriptional regulator FIU16_19175 ENOG4105CNT hydrolase family 2 FIU16_19180 ENOG4105FK9 beta-D-galactosidase beta subunit FIU16_19185 ENOG4105E5D amino acid FIU16_19190 ENOG4107W6W Conserved Protein FIU16_19195 ENOG4107WCA isomerase FIU16_19200 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FIU16_19205 ENOG4108Z3N Transcriptional regulator FIU16_19220 ENOG4108VKG metal-dependent hydrolase FIU16_19225 ENOG4108UB4 uncharacterized protein ygjQ FIU16_19230 ENOG4105EE0 oxidoreductase FIU16_19235 ENOG4105DU1 integral membrane protein, terc FIU16_19240 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FIU16_19245 ENOG4105P66 Membrane FIU16_19250 ENOG4105CTX dehydratase FIU16_19260 ENOG4105DPW Major facilitator superfamily MFS_1 FIU16_19285 ENOG4107YCY Transcriptional regulator FIU16_19290 ENOG4106W5V Membrane FIU16_19295 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) FIU16_19300 ENOG4105WAY exported protein FIU16_19305 ENOG4105NE1 Conserved Protein FIU16_19310 ENOG41090KG Inner membrane protein YqjE FIU16_19315 ENOG4105YJD FIU16_19320 ENOG4108VBZ doxx family FIU16_19325 ENOG4105CHF Glutathione S-transferase FIU16_19330 ENOG4105KAF membrAne FIU16_19340 ENOG4105CWB LysR family transcriptional Regulator FIU16_19345 ENOG4108CNN domain protein FIU16_19350 ENOG4106D80 Uncharacterized protein YhaL FIU16_19360 ENOG4105C44 Serine transporter FIU16_19365 ENOG4105EJQ L-serine dehydratase FIU16_19370 ENOG4105KME endoribonuclease L-psp FIU16_19375 ENOG4105C6N Formate acetyltransferase FIU16_19380 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FIU16_19390 ENOG4105C7B Threonine dehydratase FIU16_19395 ENOG410811B TRANSCRIPTIONal FIU16_19430 ENOG4105BZW Glycerate kinase FIU16_19435 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FIU16_19445 ENOG4105DJB Major Facilitator Superfamily FIU16_19450 ENOG4105CTX dehydratase FIU16_19455 ENOG4105ZEG Suppressor protein FIU16_19460 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression FIU16_19465 ENOG4105E98 transcriptional regulator DeoR family FIU16_19475 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB FIU16_19485 ENOG4105F3R pts system mannose fructose sorbose family iid FIU16_19490 ENOG4108YTN IIa component FIU16_19495 ENOG4105CE4 GlcNAc 6-P deacetylase FIU16_19500 ENOG4105E70 isomerase FIU16_19510 ENOG4108UZY PTS System FIU16_19515 ENOG4105ETZ PTS System FIU16_19520 ENOG4105F3R pts system mannose fructose sorbose family iid FIU16_19525 ENOG4106HBN Galactosamine-6-phosphate isomerase FIU16_19530 ENOG4105Q10 Fimbrial-like protein FIU16_19535 ENOG4108VCD Chaperone FIU16_19540 ENOG4105CW0 outer membrane usher protein FIU16_19545 ENOG4105I74 Fimbrial protein FIU16_19550 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FIU16_19570 ENOG4105W4M Transport-associated protein FIU16_19575 ENOG4107S21 permease FIU16_19580 ENOG4105K4T epimerase FIU16_19585 ENOG4107R7Y intracellular protease Pfpi family FIU16_19600 ENOG4108YYD acetyltransferase FIU16_19605 ENOG4105XPQ lipid carrier protein FIU16_19610 ENOG4105CFP Peptidase U32 FIU16_19615 ENOG4106RZ4 Peptidase U32 FIU16_19620 ENOG4105DEN Luciferase family FIU16_19625 ENOG4105CIC tryptophan-specific transport protein FIU16_19630 ENOG4105C1J atp-dependent rna helicase FIU16_19640 ENOG4105RT1 May be involved in cell division (By similarity) FIU16_19670 ENOG4105CHV Transcription elongation factor NusA FIU16_19690 ENOG4105DIJ Phosphoethanolamine transferase FIU16_19710 ENOG4105EEI dihydropteroate synthase FIU16_19715 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FIU16_19720 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FIU16_19725 ENOG4105HBR Rna-binding protein FIU16_19730 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FIU16_19735 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FIU16_19745 ENOG4105QYV Membrane FIU16_19760 ENOG4105EAH synthase FIU16_19765 ENOG4105HVQ Regulatory factor of maltose metabolism FIU16_19775 ENOG4105VFK BolA family FIU16_19780 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FIU16_19785 ENOG4105E3I toluene tolerance FIU16_19790 ENOG4107PE3 Mammalian cell entry related domain protein FIU16_19795 ENOG4105CY3 ABC transporter, permease FIU16_19800 ENOG4105DHJ ABC, transporter FIU16_19805 ENOG4105FEU K -dependent Na -Ca exchanger FIU16_19810 ENOG4105C2X Arabinose 5-phosphate isomerase FIU16_19820 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FIU16_19825 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FIU16_19830 ENOG4108IUZ ABC transporter FIU16_19835 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU16_19840 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FIU16_19845 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FIU16_19855 ENOG41080Z8 PHOSPHOCARRIER protein FIU16_19860 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FIU16_19870 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FIU16_19875 ENOG4105BZU Histidine kinase FIU16_19880 ENOG4105N5T Radical SAM Protein FIU16_19885 ENOG4105CBC glutamate synthase FIU16_19890 ENOG4105BZ8 glutamate synthase FIU16_19895 ENOG4105DFS Conserved Protein FIU16_19905 ENOG4108R66 Conserved Protein FIU16_19935 ENOG4105CEE C4-dicarboxylate transporter FIU16_19940 ENOG4105KB2 stringent starvation protein b FIU16_19945 ENOG4107MKT Stringent starvation protein a FIU16_19955 ENOG4108UJD 30S ribosomal protein S9 FIU16_19965 ENOG4105D6Z AFG1 family ATPase FIU16_19970 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FIU16_19975 ENOG4105C0H protease FIU16_19980 ENOG4105C0H protease FIU16_19995 ENOG4105RID UPF0379 protein yhcN FIU16_20000 ENOG4105UNR (Barnase) inhibitor FIU16_20020 ENOG4105CR8 Transcriptional regulator FIU16_20025 ENOG4105D1U peptidase U62 modulator of DNA gyrase FIU16_20030 ENOG4105QD6 exported protein FIU16_20035 ENOG4105C03 ribonuclease FIU16_20045 ENOG4105VQ7 Rod shape-determining protein MreD FIU16_20050 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FIU16_20055 ENOG4105DFF Rod shape-determining protein mreb FIU16_20060 ENOG41062P1 Diguanylate cyclase phosphodiesterase FIU16_20065 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FIU16_20070 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FIU16_20075 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FIU16_20080 ENOG4105RG0 Membrane FIU16_20085 ENOG4108IA2 Sodium pantothenate symporter FIU16_20095 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FIU16_20100 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FIU16_20105 ENOG4105CEC DNA methylase N-4 N-6 FIU16_20110 ENOG41061ME transport protein FIU16_20115 ENOG4108XG4 DNA-binding transcriptional regulator FIU16_20120 ENOG4105C1P efflux transporter, rnd family, mfp subunit FIU16_20125 ENOG4105BZS acriflavin resistance protein FIU16_20130 ENOG4105XCM membrane LIPOPROTEIN FIU16_20140 ENOG4105EZ7 amino acid ABC transporter FIU16_20145 ENOG4105DRP amino acid AbC transporter FIU16_20150 ENOG4105CDA abc transporter atp-binding protein FIU16_20195 ENOG4108Z0R Transferase FIU16_20200 ENOG4105SG3 Protein of unknown function (DUF1488) FIU16_20215 ENOG4108WI1 Dna topoisomerase FIU16_20225 ENOG4105C79 DNA protecting protein DprA FIU16_20245 ENOG4105C1A potassium transporter peripheral membrane FIU16_20255 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FIU16_20260 ENOG4105W1Y Transcriptional regulator FIU16_20265 ENOG4105VTS DnaJ-like, subfamily C FIU16_20275 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FIU16_20280 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FIU16_20290 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FIU16_20295 ENOG41067V7 50S ribosomal protein L36 FIU16_20300 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FIU16_20305 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FIU16_20315 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FIU16_20320 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FIU16_20330 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FIU16_20345 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FIU16_20355 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FIU16_20365 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FIU16_20370 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FIU16_20375 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FIU16_20380 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FIU16_20390 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FIU16_20395 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FIU16_20415 ENOG4108UQY Iron-storage protein FIU16_20420 ENOG4105W53 bacterioferritin-associated ferredoxin FIU16_20460 ENOG4105WWK YheO domain protein FIU16_20465 ENOG4108V1T peptidylprolyl cis-trans isomerase FIU16_20475 ENOG4108YZY peptidylprolyl cis-trans isomerase FIU16_20480 ENOG4105VKU nucleicacid-binding protein FIU16_20495 ENOG4105C5H ABC transporter FIU16_20500 ENOG4105DNZ Alpha Beta Hydrolase FIU16_20510 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FIU16_20515 ENOG4108UKZ OsmC family FIU16_20520 ENOG4107RYR Transcriptional regulator, Crp Fnr family FIU16_20525 ENOG410613R integral membrane protein, YccS YhfK family FIU16_20530 ENOG4105C8Y Acetylornithine aminotransferase FIU16_20535 ENOG4105DDQ anthranilate synthase FIU16_20540 ENOG4105MZU cell filamentation protein FIU16_20545 ENOG4106195 uncharacterized protein yhfG FIU16_20550 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FIU16_20565 ENOG4107QZF nitrite reductase NADPH large subunit FIU16_20570 ENOG4105WZK nitrite reductase NADPH small subunit FIU16_20575 ENOG4107V9H nitrite transporter FIU16_20585 ENOG4105VYH FIU16_20590 ENOG4107QHQ amino acid FIU16_20595 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FIU16_20600 ENOG4107Y0V Not clear, may be involved in an isomerization step FIU16_20605 ENOG4108KPW sugar kinase FIU16_20610 ENOG4105FDP GntR family transcriptional regulator FIU16_20615 ENOG4106PKC pyridoxal phosphate binding FIU16_20620 ENOG4106M0N transport system permease protein FIU16_20625 ENOG4105MUZ Protein of unknown function DUF2620 FIU16_20630 ENOG41080QX K07048 phosphotriesterase-related protein FIU16_20635 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FIU16_20640 ENOG4108626 Racemase FIU16_20645 ENOG4105RMW regulation of transcription, DNA-dependent FIU16_20650 ENOG4108M21 FIU16_20655 ENOG4105C31 Tryptophanyl-tRNA synthetase FIU16_20665 ENOG4105DJV ribulose-phosphate 3-epimerase FIU16_20670 ENOG4105DFE Dna adenine methylase FIU16_20675 ENOG4105EGB membrane protein DamX FIU16_20690 ENOG4105E4G Type IV pilus FIU16_20695 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FIU16_20700 ENOG4105XPX DNA utilization protein HofO FIU16_20705 ENOG41065NF Fimbrial assembly family protein FIU16_20710 ENOG4108U1Q Pilus assembly protein FIU16_20715 ENOG4108JQC penicillin-binding protein 1A FIU16_20720 ENOG4107RK2 ADP-ribose diphosphatase NudE FIU16_20725 ENOG4105DQY intracellular growth attenuator FIU16_20730 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FIU16_20735 ENOG4105VEJ Heat shock protein FIU16_20745 ENOG4108MAJ Membrane FIU16_20765 ENOG4105E0F Histidine kinase FIU16_20770 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FIU16_20775 ENOG4108RRZ Transcription elongation factor GreB FIU16_20780 ENOG4105BZM domain protein FIU16_20785 ENOG4105XFK Ferrous iron transport protein A FIU16_20790 ENOG4105CE1 Ferrous iron transport protein b FIU16_20800 ENOG4105DNE Transposase FIU16_20810 ENOG4105MJ2 Competence protein FIU16_20820 ENOG4105C6Z Gluconate FIU16_20825 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FIU16_20830 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FIU16_20845 ENOG4105E0Y RtcB Protein FIU16_20850 ENOG4105CYB regulatoR FIU16_20855 ENOG4105E98 transcriptional regulator DeoR family FIU16_20870 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FIU16_20895 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FIU16_20920 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FIU16_20925 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FIU16_20930 ENOG4105C6Z Gluconate FIU16_20935 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FIU16_20940 ENOG4105DIQ Transcriptional regulator FIU16_20945 ENOG4105C2I pirin domain protein FIU16_20950 ENOG4105D9R oxidoreductase FIU16_20955 ENOG4105WCN acetyltransferase FIU16_20960 ENOG4105GMB type VI secretion system effector, hcp1 family FIU16_20975 ENOG4106FA4 FIU16_20980 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FIU16_20985 ENOG4105WC8 Conserved Protein FIU16_20990 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FIU16_20995 ENOG4108IJ9 (ABC) transporter FIU16_21000 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FIU16_21005 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FIU16_21010 ENOG4105BZ7 extracellular solute-binding protein family 1 FIU16_21015 ENOG4108IV0 ABC, transporter FIU16_21020 ENOG4105C0Z ABC transporter FIU16_21025 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FIU16_21030 ENOG4105C32 Amino acid ABC transporter (Permease) FIU16_21035 ENOG4105CP9 extracellular ligand-binding receptor FIU16_21040 ENOG4105U59 -acetyltransferase FIU16_21045 ENOG4105CP9 extracellular ligand-binding receptor FIU16_21050 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FIU16_21055 ENOG4105CRP Part of the ABC transporter FtsEX involved in FIU16_21060 ENOG4105CAK Cell division ATP-binding protein ftsE FIU16_21065 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FIU16_21070 ENOG4106H78 methyltransferase FIU16_21075 ENOG4105MG3 Membrane FIU16_21085 ENOG4107FS9 Membrane FIU16_21100 ENOG4105EX9 Membrane FIU16_21105 ENOG4108W1V Lipoprotein FIU16_21110 ENOG4105F9N Major Facilitator Superfamily FIU16_21115 ENOG4105DSF transport protein FIU16_21120 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FIU16_21125 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FIU16_21130 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FIU16_21135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU16_21140 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FIU16_21165 ENOG4105CMI transporter FIU16_21170 ENOG4105CJ1 ABC, transporter FIU16_21175 ENOG4105D0S secretion protein (HlyD FIU16_21195 ENOG4107UNS conserved inner membrane protein FIU16_21210 ENOG4105GR3 Histidine kinase FIU16_21215 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FIU16_21220 ENOG4108PG2 copper resistance FIU16_21225 ENOG4105JDN Copper resistance protein FIU16_21230 ENOG4105VR0 copper resistance FIU16_21235 ENOG4105E3B Multicopper oxidase FIU16_21245 ENOG4105DR5 peptidase FIU16_21275 ENOG410624V efflux system protein FIU16_21325 ENOG4108YXQ IS66 Orf2 family protein FIU16_21330 ENOG4105E5H Transposase FIU16_21360 ENOG4105CBX hi0933 family FIU16_21365 ENOG4105CJ3 phosphate transporter FIU16_21375 ENOG4108M6U Universal stress protein A FIU16_21385 ENOG4105DUX Transporter FIU16_21395 ENOG4105DGW oligopeptidase A FIU16_21400 ENOG4105D6S protein involved in catabolism of external DNA FIU16_21405 ENOG4105DC8 reductase FIU16_21415 ENOG4105KBH arsR family transcriptional regulator FIU16_21420 ENOG4107R5R arsenical pump membrane protein FIU16_21425 ENOG4105K89 arsenate reductase FIU16_21445 ENOG4105Y4Z Outer Membrane Lipoprotein FIU16_21455 ENOG4105KT7 mgtC SapB transporter FIU16_21475 ENOG4105CVK Glutamate decarboxylase FIU16_21480 ENOG4105CA0 peroxidase FIU16_21490 ENOG4106S2D Transcriptional regulator FIU16_21495 ENOG4105CBN LysR family transcriptional regulator FIU16_21500 ENOG4107H3J ribonuclease FIU16_21505 ENOG4105CSH Transporter FIU16_21510 ENOG41066T0 asmA family FIU16_21515 ENOG4105CMB EAL domain-containing protein FIU16_21525 ENOG4105CS0 peptidase FIU16_21535 ENOG4105BZU Histidine kinase FIU16_21540 ENOG4105EJG cellulose synthase FIU16_21545 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FIU16_21550 ENOG4107EEX Cellulose synthase regulator protein FIU16_21555 ENOG4107QZ7 Cellulose synthase catalytic subunit FIU16_21565 ENOG410661M cytoplasmic protein FIU16_21575 ENOG4105WQA Cellulose biosynthesis protein BcsF FIU16_21580 ENOG4105D1V cellulose synthase operon protein YhjU FIU16_21625 ENOG4105C44 Serine transporter FIU16_21630 ENOG4108JQ7 (ABC) transporter FIU16_21635 ENOG4105C3U ABC transporter FIU16_21640 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FIU16_21645 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FIU16_21655 ENOG4105DEF Extracellular solute-binding protein, family 5 FIU16_21665 ENOG4105DIJ Phosphoethanolamine transferase FIU16_21670 ENOG4106UCC Fimbrial protein FIU16_21675 ENOG4105MHR Fimbrial protein FIU16_21680 ENOG4105CW0 outer membrane usher protein FIU16_21685 ENOG4108VCD Chaperone FIU16_21690 ENOG4106EAR Fimbrial protein FIU16_21695 ENOG4105FCD Major Facilitator FIU16_21700 ENOG4105EAX Putative lipase FIU16_21705 ENOG4108R3E Dna-3-methyladenine glycosylase i FIU16_21710 ENOG4105HNP -acetyltransferase FIU16_21715 ENOG4107QY8 reductase FIU16_21720 ENOG4108ZG0 Ompa motb domain protein FIU16_21730 ENOG4106JH6 (LipO)protein FIU16_21735 ENOG4105MVF Transcriptional regulator FIU16_21740 ENOG4105VEQ Cold shock protein FIU16_21745 ENOG41060TC Hok gef cell toxic protein FIU16_21755 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FIU16_21765 ENOG4105MEV Acyl-transferase FIU16_21770 ENOG4108Z12 YiaAB two helix domain-containing protein FIU16_21775 ENOG410688U Inner membrane protein yiaB FIU16_21780 ENOG4105CMG Carbohydrate kinase FIU16_21790 ENOG4105DFW ABC transporter FIU16_21795 ENOG4105C2J ABC transporter FIU16_21800 ENOG4107RNG ABC transporter FIU16_21805 ENOG4105T16 Transcriptional regulator (AraC family) FIU16_21810 ENOG4108UR8 BAX protein FIU16_21820 ENOG4105JKW Valine--pyruvate aminotransferase FIU16_21825 ENOG4108XIB electron transport protein ysaA FIU16_21830 ENOG4105J4Q Transcriptional regulator FIU16_21840 ENOG4108R66 Conserved Protein FIU16_21845 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FIU16_21865 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FIU16_21875 ENOG4105GNX MltA-interacting MipA family protein FIU16_21880 ENOG4108Q2M Transcriptional regulator FIU16_21885 ENOG4105EFX secretion protein, HlyD family FIU16_21890 ENOG4105KK7 inner membrane protein YiaW FIU16_21900 ENOG4105C26 Dehydrogenase FIU16_21905 ENOG4105C0A alcohol dehydrogenase FIU16_21910 ENOG4105EM7 Selenocysteine-specific translation elongation factor FIU16_21920 ENOG4108U78 Glutathione S-transferase FIU16_21935 ENOG4105NUP lyase containing HEAT-repeat FIU16_21965 ENOG4105EFX secretion protein, HlyD family FIU16_21970 ENOG4105FP6 Protein of unknown function (DUF3302) FIU16_21975 ENOG4105CTS PTS system mannitol-specific FIU16_21985 ENOG4105E61 Mannitol repressor protein FIU16_21995 ENOG4108YYI Protein of unknown function (DUF2810) FIU16_22005 ENOG4108WY4 inner membrane lipoprotein FIU16_22010 ENOG4105EUR Domain-Containing protein FIU16_22015 ENOG4105DAA L-lactate FIU16_22020 ENOG41073TP transcriptional regulator FIU16_22030 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FIU16_22035 ENOG4105D7W serine acetyltransferase FIU16_22050 ENOG4105VW4 glutaredoxin 3 FIU16_22055 ENOG4107YZP Rhodanese domain protein FIU16_22065 ENOG41063SB peptidase FIU16_22070 ENOG4105PXI polysaccharide deacetylase FIU16_22075 ENOG4105K64 Glycosyl transferase, family 2 FIU16_22085 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FIU16_22090 ENOG4108SEH involved in lipopolysaccharide biosynthesis FIU16_22100 ENOG4105XA0 heptosyltransferase ii FIU16_22105 ENOG4105D16 lipopolysaccharide heptosyltransferase i FIU16_22110 ENOG4108FRV O-antigen ligase FIU16_22115 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FIU16_22120 ENOG4105X1N Glycosyl transferase family 8 FIU16_22125 ENOG4108PDR lipopolysaccharide core biosynthesis protein FIU16_22130 ENOG4106AH0 Glycosyl Transferase FIU16_22135 ENOG4107543 (lipo)polysaccharide FIU16_22140 ENOG4107RJ7 Glycosyl transferase (Group 1 FIU16_22145 ENOG4105DKP glycosyl transferase, family 9 FIU16_22150 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FIU16_22165 ENOG4105W0E 50S ribosomal protein L33 FIU16_22180 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FIU16_22205 ENOG4105DSJ YicC domain protein FIU16_22210 ENOG4105F5P DNA-damage-inducible protein d FIU16_22215 ENOG4105EN6 Membrane FIU16_22225 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FIU16_22230 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FIU16_22235 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FIU16_22240 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FIU16_22245 ENOG4105CB5 ATP-dependent DNA helicase recG FIU16_22250 ENOG4105D6U Sodium Glutamate Symporter FIU16_22255 ENOG4105C2W permease FIU16_22260 ENOG4105JV1 AsmA family FIU16_22265 ENOG4105CJQ hydrolase, family 31 FIU16_22270 ENOG4105CT4 transporter FIU16_22280 ENOG4105DFP Integrase FIU16_22400 ENOG4108R0M Aminoglycoside FIU16_22500 ENOG4105F4K antigen 43 FIU16_22515 ENOG4106H6R UPF0380 protein FIU16_22525 ENOG4106549 Antirestriction protein FIU16_22530 ENOG4108YGG dna repair protein FIU16_22535 ENOG4106WJE Protein of unknown function (DUF987) FIU16_22540 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FIU16_22570 ENOG4105S8Q sugar efflux transporter FIU16_22575 ENOG4108UZ3 Transporter FIU16_22580 ENOG4105D01 (LipO)protein FIU16_22585 ENOG4105T8A Uncharacterized protein YicS FIU16_22595 ENOG4108SAJ Protein of unknown function (DUF1198) FIU16_22600 ENOG4105C7N Xanthine uracil vitamin C permease FIU16_22610 ENOG4105CXY transporter FIU16_22615 ENOG4105CXY transporter FIU16_22620 ENOG4105BZU Histidine kinase FIU16_22625 ENOG4108KX4 response regulator FIU16_22630 ENOG4105M71 acetolactate synthase 1 regulatory subunit FIU16_22635 ENOG4105C7K acetolactate synthase FIU16_22650 ENOG4105E5M Multidrug resistance protein D FIU16_22655 ENOG4105J13 transcriptional regulator FIU16_22660 ENOG4105JP4 Inner membrane protein yidG FIU16_22665 ENOG4105VG5 Membrane FIU16_22670 ENOG4106DRA Inner membrane protein YidI FIU16_22675 ENOG4105CBG Sulfatase FIU16_22680 ENOG4107RUZ Sss sodium solute transporter superfamily FIU16_22685 ENOG4108AHD Transcriptional regulator FIU16_22695 ENOG4108AHD Transcriptional regulator FIU16_22705 ENOG4105CI1 PTS System FIU16_22710 ENOG4105FDP GntR family transcriptional regulator FIU16_22730 ENOG4105R2A (LipO)protein FIU16_22735 ENOG4105D99 atp gtp-binding protein FIU16_22745 ENOG4105DJB Major Facilitator Superfamily FIU16_22755 ENOG4108RTU Aldolase FIU16_22760 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FIU16_22765 ENOG4105EMF GntR family transcriptional regulator FIU16_22770 ENOG410657R replicase EC 2.7 FIU16_22775 ENOG410667J hydrolase FIU16_22780 ENOG4105VP5 Bacterial protein of unknown function (DUF937) FIU16_22785 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FIU16_22795 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FIU16_22845 ENOG4108P6C Tryptophan transporter of low affinity FIU16_22860 ENOG4105E8Q phosphopantetheinyl transferase FIU16_22865 ENOG4108YYH Nadph-dependent fmn reductase FIU16_22870 ENOG4105C7N Xanthine uracil vitamin C permease FIU16_22875 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FIU16_22885 ENOG4106611 bacteriocin immunity FIU16_22890 ENOG4107VKM 6-phosphogluconolactonase FIU16_22895 ENOG4105DYC esterase FIU16_22905 ENOG4105CS2 ec 3.2.1.21 FIU16_22910 ENOG4105C5Y PTS System FIU16_22920 ENOG4108UTW Plays a role in the regulation of phosphate uptake FIU16_22925 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FIU16_22930 ENOG4105E2Z phosphate ABC transporter (Permease FIU16_22935 ENOG4105C8U phosphate abc transporter FIU16_22940 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FIU16_22950 ENOG4105CW0 outer membrane usher protein FIU16_22960 ENOG4108RQP Major type 1 subunit fimbrin FIU16_22965 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FIU16_23010 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FIU16_23020 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FIU16_23035 ENOG4105QTB Flavodoxin FIU16_23040 ENOG4108VVK transcriptional Regulator, AsnC FIU16_23070 ENOG4105C2J ABC transporter FIU16_23075 ENOG4105CNN ABC, transporter FIU16_23080 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FIU16_23085 ENOG4108RVA ribokinase FIU16_23090 ENOG4105ETE Transcriptional regulator (LacI family FIU16_23095 ENOG4105C0R drug resistance transporter emrb qaca subfamily FIU16_23100 ENOG4107EJG GntR family transcriptional regulator FIU16_23140 ENOG4108WFC UPF0438 protein yifE FIU16_23145 ENOG4105C0P Mg chelatase subunit ChlI FIU16_23165 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FIU16_23170 ENOG4105CM2 brancheD-chain amino acid aminotransferase FIU16_23180 ENOG4105C7B Threonine dehydratase FIU16_23185 ENOG4105EMY transcriptional regulator FIU16_23195 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FIU16_23205 ENOG4105C4R Atp-dependent dna helicase FIU16_23220 ENOG4105K63 Thioredoxin FIU16_23235 ENOG4105ESV Glycosyl transferase, family 4 FIU16_23240 ENOG4105SFE lipopolysaccharide biosynthesis protein FIU16_23245 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FIU16_23250 ENOG4108IJ1 Dehydrogenase FIU16_23255 ENOG4105C1B dTDP-glucose 4-6-dehydratase FIU16_23260 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FIU16_23265 ENOG4108WJ1 acetyltransferase FIU16_23270 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FIU16_23275 ENOG4105EGZ biosynthesis protein FIU16_23295 ENOG4105C85 amino acid FIU16_23320 ENOG4105C4X radical SAM domain protein FIU16_23325 ENOG410601J HemY protein FIU16_23330 ENOG4105ECF c-methyltransferase FIU16_23335 ENOG41076E6 Uroporphyrinogen-III Synthase FIU16_23345 ENOG4107T0K Adenylate cyclase FIU16_23370 ENOG4105S7Z (LipO)protein FIU16_23380 ENOG4105CT0 Protein of unknown function, DUF484 FIU16_23390 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FIU16_23395 ENOG4105C4R Atp-dependent dna helicase FIU16_23400 ENOG4108T58 Mg2 transport protein CorA FIU16_23405 ENOG4107QUT magnesium and cobalt transport protein CorA FIU16_23420 ENOG4107QUT magnesium and cobalt transport protein CorA FIU16_23435 ENOG4105FR1 rard protein FIU16_23440 ENOG4108VUY thioesterase Superfamily protein FIU16_23445 ENOG4105HDD phospholipase FIU16_23450 ENOG4105C9U ATP-dependent DNA helicase RecQ FIU16_23465 ENOG4108EUD Lysophospholipase FIU16_23470 ENOG4105DQF Hydrolase FIU16_23475 ENOG4105EMK carboxylate amino acid amine transporter FIU16_23480 ENOG4105DZ2 Transcriptional regulator FIU16_23490 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FIU16_23495 ENOG4108I5U Uridine phosphorylase FIU16_23500 ENOG4105CGY Dna recombination protein FIU16_23510 ENOG4105JC1 sterol-binding domain protein FIU16_23520 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FIU16_23525 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FIU16_23530 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FIU16_23540 ENOG4105MDZ Transcriptional activator rfaH FIU16_23545 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FIU16_23550 ENOG4107QK7 reductase FIU16_23570 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FIU16_23575 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FIU16_23580 ENOG4108RR8 protoporphyrinogen oxidase FIU16_23610 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FIU16_23615 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FIU16_23620 ENOG4105PC1 Conserved Protein FIU16_23625 ENOG4105E27 serine threonine protein kinase FIU16_23630 ENOG4108Z33 Thiol disulfide Interchange Protein FIU16_23640 ENOG4106HNH Acyl-transferase FIU16_23650 ENOG4105C2M dna polymerase I FIU16_23665 ENOG4105D4P Coproporphyrinogen iii oxidase FIU16_23670 ENOG4106FIY FIU16_23675 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FIU16_23680 ENOG4105CUX Signal transduction histidine kinase FIU16_23685 ENOG4105C5F glutamine synthetase FIU16_23695 ENOG4108K85 Transcriptional regulator FIU16_23700 ENOG4108KHF Resistance protein FIU16_23705 ENOG4105R9B Major Facilitator FIU16_23710 ENOG4105E98 transcriptional regulator DeoR family FIU16_23715 ENOG4108MGF sugar kinase FIU16_23720 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FIU16_23725 ENOG4105D2M Aldolase FIU16_23730 ENOG4105CPQ Dehydrogenase FIU16_23740 ENOG4105CSH Transporter FIU16_23750 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FIU16_23765 ENOG4105SUU thioesterase domain FIU16_23775 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system FIU16_23785 ENOG4106UEE Transcriptional regulator FIU16_23790 ENOG41068KX affects formate dehydrogenase-N FIU16_23800 ENOG4108MG3 formate dehydrogenase FIU16_23805 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FIU16_23820 ENOG4108V87 frv operon regulatory protein FIU16_23825 ENOG4106C3V frv operon regulatory protein FIU16_23830 ENOG4105CN9 Peptidase m42 family protein FIU16_23835 ENOG4105DM4 PTS System FIU16_23840 ENOG41064BA PTS system, fructose-specific, IIA component FIU16_23880 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FIU16_23890 ENOG4108RPX mosc domain containing protein FIU16_23895 ENOG4105E0F Histidine kinase FIU16_23900 ENOG4105E3W Two component transcriptional regulator (Winged helix family FIU16_23905 ENOG4105FMW periplasmic FIU16_23920 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FIU16_23935 ENOG4105EBK exported protein FIU16_23940 ENOG4108VTS Membrane FIU16_23945 ENOG41065TG regulatoR FIU16_23955 ENOG4105DP0 ferredoxin-NADP reductase FIU16_23960 ENOG4105CBT Fructose-1,6-bisphosphatase FIU16_23970 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FIU16_23985 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FIU16_24000 ENOG41063M6 Cell Division Protein FIU16_24005 ENOG4105ETE Transcriptional regulator (LacI family FIU16_24010 ENOG4105C25 Primosomal protein n' FIU16_24020 ENOG4105CNA YD repeat protein FIU16_24045 ENOG4105C28 cystathionine FIU16_24050 ENOG4105CFH Aspartokinase FIU16_24055 ENOG4105SYT Methylenetetrahydrofolate reductase FIU16_24060 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) FIU16_24065 ENOG4108Q5Y Membrane FIU16_24070 ENOG4108XC3 NADH ubiquinone oxidoreductase FIU16_24075 ENOG4105DCT glycerol dehydrogenase FIU16_24080 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FIU16_24085 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FIU16_24090 ENOG4105DM4 PTS System FIU16_24095 ENOG4108YRF PTS System FIU16_24100 ENOG4105C6N Formate acetyltransferase FIU16_24105 ENOG4108AHH pyruvate formate lyase II activase FIU16_24110 ENOG4108XCZ PTS System FIU16_24115 ENOG4106R3P AraC family transcriptional regulator FIU16_24120 ENOG4105DIJ Phosphoethanolamine transferase FIU16_24135 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FIU16_24140 ENOG4105CAS nag kinase FIU16_24155 ENOG4105CXK mandelate racemase muconate lactonizing FIU16_24160 ENOG4108I5G Major Facilitator superfamily FIU16_24165 ENOG4105C5Q Transcriptional regulator FIU16_24175 ENOG4105EJ2 Transcriptional regulator FIU16_24180 ENOG4108Y73 Membrane FIU16_24225 ENOG4105D4A Cell wall formation (By similarity) FIU16_24230 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FIU16_24265 ENOG4105PM1 preprotein translocase subunit SecE FIU16_24270 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FIU16_24305 ENOG410645W Thiamin biosynthesis protein ThiH FIU16_24310 ENOG4105D41 biosynthesis protein thiH FIU16_24320 ENOG4105WHD thiamine biosynthesis protein ThiS FIU16_24325 ENOG4105D06 uba thif-type nad fad binding protein FIU16_24360 ENOG4105R2J Conserved Protein FIU16_24365 ENOG4105K70 DNA-binding protein FIU16_24370 ENOG4108T8B Protein of unknown function (DUF1481) FIU16_24375 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism FIU16_24380 ENOG4105BZU Histidine kinase FIU16_24385 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FIU16_24390 ENOG4105C12 Phosphoribosylglycinamide synthetase FIU16_24420 ENOG4105K5X acetyltransferase FIU16_24430 ENOG4107QP3 malate synthase g FIU16_24435 ENOG4108I9X Isocitrate lyase FIU16_24450 ENOG41069M3 Transcriptional regulator FIU16_24455 ENOG4105C3R Methionine synthase FIU16_24460 ENOG4105EAM Na Pi-cotransporter FIU16_24470 ENOG4105FE9 pseudouridine synthase FIU16_24475 ENOG4108ZR5 Conserved Protein FIU16_24485 ENOG410756H nucleotidyltransferase FIU16_24490 ENOG4108WZA zeta toxin FIU16_24495 ENOG4105CFH Aspartokinase FIU16_24510 ENOG4108MDC (LipO)protein FIU16_24515 ENOG4108Q9C Periplasmic Protein FIU16_24520 ENOG4105E3R (LipO)protein FIU16_24535 ENOG4107QNK )-transporter FIU16_24540 ENOG4105EG2 ABC transporter, permease FIU16_24545 ENOG4105D56 permease protein FIU16_24550 ENOG4107FKK extracellular solute-binding protein family 1 FIU16_24555 ENOG4108IJ9 (ABC) transporter FIU16_24565 ENOG4107W52 maltose operon periplasmic protein FIU16_24590 ENOG41080IJ Diacylglycerol kinase FIU16_24600 ENOG4107R73 Mate efflux family protein FIU16_24605 ENOG4105VDW Csbd family FIU16_24610 ENOG4105MYN Zinc uptake regulation protein FIU16_24625 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FIU16_24630 ENOG4105P4Z Phage shock protein G FIU16_24635 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FIU16_24640 ENOG4105CDU Replicative dna helicase FIU16_24645 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FIU16_24650 ENOG4105CGF Aromatic amino acid aminotransferase FIU16_24665 ENOG4105F0S class B acid phosphatase FIU16_24670 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FIU16_24675 ENOG4105MSB protein, conserved in bacteria FIU16_24680 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FIU16_24685 ENOG4108UUM single-stranded DNA-binding protein FIU16_24690 ENOG4105PMV Membrane FIU16_24695 ENOG4108M8H domain protein FIU16_24700 ENOG4108W3Q Transcriptional regulator FIU16_24705 ENOG4108Z4X TRANSCRIPTIONal FIU16_24710 ENOG4105C7N Xanthine uracil vitamin C permease FIU16_24715 ENOG4105EEQ Na H antiporter FIU16_24730 ENOG41062QD Membrane FIU16_24735 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FIU16_24745 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FIU16_24750 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FIU16_24755 ENOG4105DVI reductase, NrfD FIU16_24760 ENOG4108QKW cytochrome c-type biogenesis protein FIU16_24770 ENOG4108W0S formate-dependent nitrite reductase complex FIU16_24775 ENOG4105CK2 sodium dicarboxylate symporter FIU16_24780 ENOG41082ND Uncharacterized protein yjcO FIU16_24790 ENOG4105ETP RND efflux system, outer membrane lipoprotein FIU16_24795 ENOG4108MI0 Resistance protein FIU16_24800 ENOG4105J12 Multidrug resistance protein mdtN FIU16_24810 ENOG4105EUZ Beta-lactamase domain protein FIU16_24815 ENOG4108YZG isomerase FIU16_24820 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 FIU16_24825 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein FIU16_24830 ENOG410849A acetyltransferase, (GNAT) family FIU16_24835 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) FIU16_24840 ENOG4105FD8 phosphonate metabolism protein PhnM FIU16_24845 ENOG4105HRV phosphonate c-p lyase system protein phnl FIU16_24850 ENOG4105ENV phosphonate C-P lyase system protein PhnK FIU16_24855 ENOG4105FT8 Phosphonate metabolism FIU16_24860 ENOG4105EKV Phosphonate metabolism protein FIU16_24865 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH FIU16_24870 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG FIU16_24875 ENOG4107RJJ Transcriptional regulator FIU16_24885 ENOG4105EHI Phosphonate ABC transporter, periplasmic FIU16_24890 ENOG4105D5T phosphonate abc transporter FIU16_24895 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FIU16_24900 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FIU16_24905 ENOG4108F5E vimentin FIU16_24910 ENOG4108YIV FIU16_24915 ENOG4105CSH Transporter FIU16_24925 ENOG4105ECM Sensor protein basS pmrB FIU16_24930 ENOG4105XJC Two component transcriptional regulator (Winged helix family FIU16_24935 ENOG4105DIJ Phosphoethanolamine transferase FIU16_24940 ENOG4105D5Q Arginine ornithine antiporter FIU16_24945 ENOG4106ZGR Transcriptional regulator FIU16_24950 ENOG4105CXN decarboxylase FIU16_24955 ENOG4108K2B transcriptional regulator FIU16_24960 ENOG4105F8D glycoside hydrolase family 4 FIU16_24965 ENOG4105CT4 transporter FIU16_24970 ENOG4108R5S membrane FIU16_24975 ENOG4107GFK fumarate FIU16_24980 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FIU16_24985 ENOG4108MRH transcriptional regulatory protein FIU16_24990 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FIU16_24995 ENOG4105VR1 Pfam:DUF1271 FIU16_25000 ENOG410830R acetyltransferase FIU16_25015 ENOG4105CRK lysyL-tRNA synthetase FIU16_25020 ENOG4105DUX Transporter FIU16_25025 ENOG4105CXN decarboxylase FIU16_25030 ENOG4105D5Q Arginine ornithine antiporter FIU16_25040 ENOG4108M3R transcriptional activator CadC FIU16_25065 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FIU16_25070 ENOG4106WJE Protein of unknown function (DUF987) FIU16_25075 ENOG4108YGG dna repair protein FIU16_25080 ENOG4105MFG Antirestriction protein FIU16_25100 ENOG4105EKQ RNA-directed DNA polymerase FIU16_25110 ENOG4105I1J Autotransporter FIU16_25170 ENOG4105DUU IucA IucC family protein FIU16_25175 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) FIU16_25195 ENOG4105EKQ RNA-directed DNA polymerase FIU16_25240 ENOG4108YXQ IS66 Orf2 family protein FIU16_25245 ENOG4105E5H Transposase FIU16_25255 ENOG4105I1J Autotransporter FIU16_25310 ENOG4108SIC Transcriptional regulator FIU16_25325 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FIU16_25330 ENOG4108IJ0 Aspartate ammonia-lyase FIU16_25335 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FIU16_25340 ENOG4105DVH amino acid FIU16_25355 ENOG4108ZVF (LipO)protein FIU16_25360 ENOG4105MTB Uncharacterized protein YjeJ FIU16_25365 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FIU16_25375 ENOG4106HKS Entericidin EcnA/B family FIU16_25380 ENOG4106BSU Entericidin B FIU16_25385 ENOG4105KPY Small multidrug resistance protein FIU16_25390 ENOG4105QNF Outer membrane lipoprotein FIU16_25395 ENOG41066YJ Beta-lactamase FIU16_25410 ENOG4105E33 succinate dehydrogenase FIU16_25415 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FIU16_25425 ENOG4107SC7 Inner membrane transporter yjeM FIU16_25430 ENOG4106V5W FIU16_25435 ENOG4106CG8 Inner membrane protein YjeO FIU16_25440 ENOG4105EGS Mechanosensitive ion channel FIU16_25480 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FIU16_25485 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FIU16_25490 ENOG4105K8N protein family UPF0079, ATPase FIU16_25495 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FIU16_25510 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FIU16_25515 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FIU16_25520 ENOG4107QJR hflk protein FIU16_25525 ENOG4105EPW hflc protein FIU16_25545 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FIU16_25550 ENOG4105C2N RNA methyltransferase TrmH family group 3 FIU16_25555 ENOG4105FUX Conserved Protein FIU16_25560 ENOG4108P9J Phage shock protein A FIU16_25565 ENOG4107VNS Protein of unknown function (DUF2491) FIU16_25575 ENOG4108KXT Conserved Protein FIU16_25580 ENOG4106032 Glutathionylspermidine synthase FIU16_25585 ENOG4105CSU acyl-Coa dehydrogenase FIU16_25590 ENOG4105S17 UPF0379 protein yjfN FIU16_25595 ENOG4105WSB biofilm stress and motility protein A FIU16_25600 ENOG4108MXZ Esterase FIU16_25615 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FIU16_25620 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport FIU16_25645 ENOG4105R3P Inner membrane protein yagU FIU16_25650 ENOG4105KIT UPF0379 protein yjfY FIU16_25665 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FIU16_25685 ENOG4108RS6 transposase FIU16_25690 ENOG4105D7V transposase FIU16_25700 ENOG4105FHY Opacity-associated protein A FIU16_25710 ENOG4108V1T peptidylprolyl cis-trans isomerase FIU16_25715 ENOG4105C85 amino acid FIU16_25725 ENOG4105DXC membrane FIU16_25730 ENOG4105ECR NmrA family FIU16_25735 ENOG4105KVH Transcriptional regulator FIU16_25740 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FIU16_25745 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FIU16_25750 ENOG4108UUE Transcriptional regulator FIU16_25755 ENOG41061GZ Protein of unknown function (DUF1107) FIU16_25760 ENOG4105C37 (CBS) domain FIU16_25770 ENOG4105CFU surface antigen FIU16_25775 ENOG4105MA0 exported protein FIU16_25780 ENOG4108ZHD aig2 family FIU16_25785 ENOG41087RY SpoVT_AbrB FIU16_25790 ENOG4105MZG transcriptional modulator of maze toxin, mazf FIU16_25795 ENOG4105F0N pyrophosphate phospho-hydrolase FIU16_25800 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator FIU16_25805 ENOG4105C2J ABC transporter FIU16_25810 ENOG4107R9N ABC transporter FIU16_25815 ENOG41062B0 ABC transporter, permease FIU16_25825 ENOG4105DFU Cell wall formation (By similarity) FIU16_25835 ENOG4105CMS peptidase U62, modulator of DNA gyrase FIU16_25845 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FIU16_25850 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FIU16_25860 ENOG4105CG3 alpha amylase, catalytic region FIU16_25865 ENOG4105C5Y PTS System FIU16_25870 ENOG4105D4X repressor FIU16_25880 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FIU16_25895 ENOG4105KME endoribonuclease L-psp FIU16_25910 ENOG41077AM PyrBI operon attenuator FIU16_25915 ENOG4108UQ8 endoribonuclease L-psp FIU16_25920 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FIU16_25925 ENOG4108XFH Transcriptional regulator FIU16_25930 ENOG4105XEP YhcH YjgK YiaL family protein FIU16_25960 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FIU16_25965 ENOG4108MJ3 acetyltransferase FIU16_25970 ENOG4108M3P Membrane FIU16_25975 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FIU16_25980 ENOG4105MYG DNA polymerase iii, chi subunit FIU16_25990 ENOG4108M8S permease YjgP YjgQ family protein FIU16_25995 ENOG4108K5H permease YjgP YjgQ family protein FIU16_26000 ENOG4105D7A ATP-binding protein FIU16_26005 ENOG4105K2J Transcriptional regulator FIU16_26010 ENOG4105C6Z Gluconate FIU16_26015 ENOG4105CHR reductase FIU16_26020 ENOG4105CPQ Dehydrogenase FIU16_26025 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FIU16_26030 ENOG4105DQ4 alcohol dehydrogenase FIU16_26085 ENOG4107R3N Filamentation induced by cAMP protein fic FIU16_26100 ENOG4105QEK Transcriptional regulator FIU16_26110 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) FIU16_26120 ENOG410613R integral membrane protein, YccS YhfK family FIU16_26145 ENOG4106ETB IIa component FIU16_26155 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FIU16_26175 ENOG4105EDR glucose galactose transporter FIU16_26180 ENOG4108RVA ribokinase FIU16_26185 ENOG4107FB0 transcriptional regulator DeoR family FIU16_26190 ENOG4105M71 acetolactate synthase 1 regulatory subunit FIU16_26205 ENOG4105E5H Transposase FIU16_26210 ENOG4108YXQ IS66 Orf2 family protein FIU16_26220 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FIU16_26235 ENOG4105EXU Membrane FIU16_26245 ENOG4105C94 Transporter FIU16_26255 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FIU16_26260 ENOG4108MJ5 VirK protein FIU16_26265 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FIU16_26270 ENOG4107BJW polysaccharide deacetylase FIU16_26285 ENOG4105EKQ RNA-directed DNA polymerase FIU16_26300 ENOG4105E0A ABC, transporter FIU16_26305 ENOG4108IHU transport system permease protein FIU16_26310 ENOG4105DQ5 transport system permease protein FIU16_26315 ENOG4108HUF Transporter FIU16_26320 ENOG4105GAV receptor FIU16_26325 ENOG4108S3W Anti-feci sigma factor, fecr FIU16_26330 ENOG4108SF5 RNA Polymerase FIU16_26360 ENOG4105E5H Transposase FIU16_26365 ENOG4108YXQ IS66 Orf2 family protein FIU16_26395 ENOG4105KF5 hemolysin expression-modulating protein FIU16_26455 ENOG4107EFN gluconate transport system permease 3 FIU16_26465 ENOG4105DEI Mannitol dehydrogenase FIU16_26470 ENOG4105C6F GntR Family Transcriptional Regulator FIU16_26490 ENOG4107YNJ LysR family Transcriptional regulator FIU16_26495 ENOG4105DYB Isoaspartyl dipeptidase FIU16_26500 ENOG4108P2H Inner membrane protein YjiG FIU16_26505 ENOG41074DU domain protein FIU16_26515 ENOG4105CBP Major Facilitator FIU16_26530 ENOG4105CIZ coA-substrate-specific enzyme activase FIU16_26535 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FIU16_26540 ENOG4106BRA Membrane FIU16_26545 ENOG41083G8 Multidrug resistance protein MdtM FIU16_26555 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FIU16_26560 ENOG4106DIZ Domain of unknown function (DUF1127) FIU16_26580 ENOG4107QTH restriction modification system DNA specificity domain FIU16_26590 ENOG4108F3G Type I restriction-modification system, R subunit FIU16_26600 ENOG4105CKI cobalamin synthesis protein FIU16_26605 ENOG4105VCD cytoplasmic protein FIU16_26610 ENOG4105D22 carbon starvation protein FIU16_26615 ENOG4105C8Q Methyl-accepting chemotaxis FIU16_26620 ENOG4108I5G Major Facilitator superfamily FIU16_26625 ENOG410617M Transcriptional regulator FIU16_26630 ENOG4105CPQ Dehydrogenase FIU16_26640 ENOG4105RI1 glycoprotein receptor FIU16_26645 ENOG4106CVF DNA replication protein FIU16_26655 ENOG4107XM3 UPF0442 protein FIU16_26660 ENOG4105DWK Membrane FIU16_26665 ENOG4108N8T regulatoR FIU16_26670 ENOG4108T94 DNA-binding transcriptional activator BglJ FIU16_26675 ENOG4108819 ferric iron reductase FIU16_26680 ENOG4105YBH Protein of unknown function (DUF1435) FIU16_26705 ENOG4108WPU DNA polymerase III subunit psi FIU16_26710 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FIU16_26715 ENOG4105PAD Hydrolase FIU16_26725 ENOG4105K3G Periplasmic Protein FIU16_26735 ENOG4108NRW Phospholipase, patatin family FIU16_26740 ENOG4105EYA deoxyribonuclease FIU16_26745 ENOG41076CZ activating enzyme FIU16_26750 ENOG4105G0K glycine radical enzyme YjjI family FIU16_26780 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) FIU16_26785 ENOG4105EAC phosphoserine phosphatase FIU16_26790 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FIU16_26795 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FIU16_26800 ENOG4105C5H ABC transporter FIU16_26805 ENOG4107SC1 transglycosylase FIU16_26825 ENOG4105UEI Transcriptional Regulator AraC Family FIU16_26830 ENOG4108RH0 Crea protein FIU16_26835 ENOG4105E3W Two component transcriptional regulator (Winged helix family FIU16_26840 ENOG4105EB3 Histidine kinase FIU16_26845 ENOG4105CT7 inner membrane cred family protein FIU16_26850 ENOG41065U4 response regulator FIU16_26855 ENOG410759A FIU16_26860 ENOG4106FVC RNA methyltransferase FIU16_26870 ENOG4105CFH Aspartokinase FIU16_26880 ENOG4105D98 threonine synthase FIU16_26885 ENOG41062C6 Protein of unknown function (DUF2502) FIU16_26895 ENOG4105BZG amino acid carrier protein FIU16_26905 ENOG4108RIR Molybdenum cofactor biosynthesis protein FIU16_26910 ENOG4106HK8 GPR1 FUN34 yaaH family protein FIU16_26915 ENOG4108QUJ UPF0174 protein YaaW FIU16_26935 ENOG4105WI6 cell killing protein encoded within cryptic prophage FIU16_26945 ENOG41063Z6 transcriptional regulator, lysR family FIU16_26970 ENOG410647N response to DNA damage stimulus FIU16_26975 ENOG4105DTN riboflavin biosynthesis protein ribF FIU16_26990 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FIU16_27010 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FIU16_27015 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FIU16_27020 ENOG4108XNW Transcriptional activatory protein CaiF FIU16_27030 ENOG4106YT9 Enoyl-CoA hydratase FIU16_27065 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FIU16_27070 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein FIU16_27075 ENOG4105C54 Major Facilitator superfamily FIU16_27090 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FIU16_27115 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FIU16_27120 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FIU16_27125 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) FIU16_27130 ENOG4105D3G Pseudouridine synthase FIU16_27155 ENOG4108PCX Major Facilitator