locus-tag	class	description
FIU16_00055	COG1136	(ABC) transporter
FIU16_00055	COG0577	efflux transmembrane transporter activity
FIU16_00070	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_00080	COG3436	PFAM IS66 Orf2 family protein
FIU16_00155	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FIU16_00165	COG3436	PFAM IS66 Orf2 family protein
FIU16_00175	COG4372	Transposase
FIU16_00180	COG3436	PFAM IS66 Orf2 family protein
FIU16_00185	COG2963	transposase activity
FIU16_00200	COG3039	Transposase
FIU16_00285	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
FIU16_00400	COG3436	PFAM IS66 Orf2 family protein
FIU16_00405	COG4372	Transposase
FIU16_00420	COG2963	transposase activity
FIU16_00435	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FIU16_00440	COG3039	Transposase
FIU16_00490	COG3344	reverse transcriptase
FIU16_00495	COG3385	transposase activity
FIU16_00520	COG3039	Transposase
FIU16_00535	COG0417	DNA replication proofreading
FIU16_00540	COG0235	Class ii aldolase
FIU16_00555	COG4977	sequence-specific DNA binding
FIU16_00560	COG0586	Pfam SNARE associated Golgi protein
FIU16_00570	COG1178	ABC-type Fe3 transport system permease component
FIU16_00575	COG4143	(ABC) transporter
FIU16_00590	COG2814	Major facilitator Superfamily
FIU16_00605	COG0473	3-isopropylmalate dehydrogenase activity
FIU16_00620	COG0583	DNA-binding transcription factor activity
FIU16_00625	COG0028	Belongs to the TPP enzyme family
FIU16_00630	COG0440	acetolactate synthase activity
FIU16_00640	COG1609	Transcriptional regulator
FIU16_00655	COG3116	cell division
FIU16_00660	COG0768	penicillin binding
FIU16_00665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU16_00670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU16_00685	COG0772	Belongs to the SEDS family
FIU16_00700	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU16_00705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU16_00710	COG0849	cell division
FIU16_00715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU16_00735	COG0494	nUDIX hydrolase
FIU16_00750	COG0237	dephospho-CoA kinase activity
FIU16_00760	COG1459	type II secretion system
FIU16_00765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU16_00770	COG4969	Belongs to the N-Me-Phe pilin family
FIU16_00775	COG0157	Belongs to the NadC ModD family
FIU16_00780	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU16_00785	COG3725	Membrane protein required for beta-lactamase induction
FIU16_00790	COG1113	amino acid transport
FIU16_00795	COG2186	Transcriptional regulator
FIU16_00800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIU16_00805	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU16_00810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU16_00815	COG3064	Membrane
FIU16_00820	COG1049	propionate catabolic process, 2-methylcitrate cycle
FIU16_00845	COG2132	Multicopper oxidase
FIU16_00850	COG4993	Dehydrogenase
FIU16_00855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FIU16_00860	COG0288	reversible hydration of carbon dioxide
FIU16_00865	COG1131	(ABC) transporter
FIU16_00870	COG0842	Transport permease protein
FIU16_00875	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_00880	COG0726	polysaccharide deacetylase
FIU16_00890	COG5464	transposase or invertase
FIU16_00905	COG3539	Fimbrial protein
FIU16_00910	COG3539	Fimbrial protein
FIU16_00915	COG3539	Fimbrial protein
FIU16_00920	COG3539	Fimbrial protein
FIU16_00925	COG3188	usher protein
FIU16_00930	COG3121	Chaperone
FIU16_00935	COG3539	Fimbrial protein
FIU16_00940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU16_00945	COG0617	tRNA 3'-terminal CCA addition
FIU16_00950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU16_00955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU16_00965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FIU16_00970	COG1643	Atp-dependent helicase
FIU16_00975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU16_00980	COG4774	siderophore transport
FIU16_00985	COG1120	ATPase activity
FIU16_00990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU16_00995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU16_01020	COG2860	membrane
FIU16_01025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU16_01040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU16_01045	COG3835	regulator
FIU16_01065	COG0024	Methionine aminopeptidase
FIU16_01090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIU16_01095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU16_01100	COG0575	Belongs to the CDS family
FIU16_01105	COG0750	zinc metalloprotease
FIU16_01115	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FIU16_01120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU16_01145	COG0587	DNA-directed DNA polymerase activity
FIU16_01160	COG0346	lactoylglutathione lyase activity
FIU16_01170	COG4568	rho-dependent transcription termination
FIU16_01180	COG4681	YaeQ
FIU16_01185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU16_01190	COG3015	lipoprotein NlpE involved in copper resistance
FIU16_01200	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_01215	COG1720	tRNA m6t6A37 methyltransferase activity
FIU16_01225	COG1464	Belongs to the NlpA lipoprotein family
FIU16_01230	COG2011	ABC-type metal ion transport system permease component
FIU16_01235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU16_01240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU16_01275	COG0656	L-ascorbic acid biosynthetic process
FIU16_01280	COG0583	DNA-binding transcription factor activity
FIU16_01290	COG2226	methyltransferase
FIU16_01295	COG0741	lytic transglycosylase activity
FIU16_01295	COG1388	LysM domain
FIU16_01305	COG2226	methyltransferase
FIU16_01315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_01335	COG4104	PAAR repeat-containing protein
FIU16_01340	COG3157	Type VI secretion system effector, Hcp
FIU16_01425	COG3501	Rhs element vgr protein
FIU16_01460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU16_01470	COG1960	acyl-CoA dehydrogenase activity
FIU16_01480	COG0121	glutamine amidotransferase
FIU16_01485	COG3034	peptidoglycan biosynthetic process
FIU16_01490	COG3041	Addiction module toxin RelE StbE family
FIU16_01495	COG3077	Addiction module antitoxin, RelB DinJ family
FIU16_01500	COG0791	NLP P60 protein
FIU16_01530	COG0454	-acetyltransferase
FIU16_01535	COG1690	Belongs to the RtcB family
FIU16_01540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU16_01545	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU16_01565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU16_01660	COG3039	Transposase
FIU16_01675	COG0583	DNA-binding transcription factor activity
FIU16_01680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIU16_01685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU16_01690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU16_01695	COG2080	2 iron, 2 sulfur cluster binding
FIU16_01700	COG3477	response to acidic pH
FIU16_01710	COG3121	Chaperone
FIU16_01720	COG3188	usher protein
FIU16_01765	COG1388	LysM domain
FIU16_01770	COG2207	Transcriptional regulator
FIU16_01770	COG3708	Transcriptional regulator
FIU16_01785	COG3039	Transposase
FIU16_01800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU16_01805	COG2207	Transcriptional regulator
FIU16_01810	COG0247	lactate metabolic process
FIU16_01815	COG1139	Iron-sulfur cluster binding protein
FIU16_01820	COG1556	Lactate utilization protein
FIU16_01845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU16_01855	COG2771	luxR family
FIU16_01855	COG2200	EAL domain
FIU16_01860	COG0583	DNA-binding transcription factor activity
FIU16_01870	COG0666	response to abiotic stimulus
FIU16_01880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU16_01885	COG1304	FMN binding
FIU16_01890	COG0549	Belongs to the carbamate kinase family
FIU16_01895	COG0402	S-adenosylhomocysteine deaminase activity
FIU16_01905	COG1879	ABC-type sugar transport system periplasmic component
FIU16_01910	COG1129	ABC transporter
FIU16_01915	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_01925	COG1064	alcohol dehydrogenase
FIU16_01940	COG1280	lysine exporter protein (LysE YggA)
FIU16_01950	COG3829	transcription factor binding
FIU16_01955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU16_01960	COG0372	Belongs to the citrate synthase family
FIU16_01965	COG2079	MmgE PrpD family protein
FIU16_01970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU16_01975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIU16_01980	COG0402	S-adenosylhomocysteine deaminase activity
FIU16_01985	COG0583	DNA-binding transcription factor activity
FIU16_01990	COG0288	reversible hydration of carbon dioxide
FIU16_02000	COG2807	transmembrane transport
FIU16_02005	COG0110	maltose O-acetyltransferase activity
FIU16_02010	COG2223	nitrite transmembrane transporter activity
FIU16_02015	COG3250	beta-galactosidase activity
FIU16_02020	COG1609	Transcriptional regulator
FIU16_02025	COG1414	Transcriptional regulator
FIU16_02060	COG2814	Major facilitator Superfamily
FIU16_02065	COG3122	Protein conserved in bacteria
FIU16_02095	COG1215	transferase activity, transferring glycosyl groups
FIU16_02100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIU16_02105	COG4521	taurine ABC transporter
FIU16_02110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FIU16_02115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU16_02120	COG2175	clavaminate synthase activity
FIU16_02125	COG0113	porphobilinogen synthase activity
FIU16_02130	COG3468	outer membrane autotransporter barrel domain protein
FIU16_02135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU16_02140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU16_02145	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FIU16_02165	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU16_02175	COG1785	Belongs to the alkaline phosphatase family
FIU16_02185	COG3706	GGDEF domain
FIU16_02190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU16_02210	COG4126	flavin adenine dinucleotide binding
FIU16_02230	COG1940	carbohydrate kinase activity
FIU16_02235	COG2814	Major facilitator Superfamily
FIU16_02240	COG0419	ATPase involved in DNA repair
FIU16_02245	COG0420	3'-5' exonuclease activity
FIU16_02250	COG0745	RESPONSE REGULATOR receiver
FIU16_02255	COG5002	protein histidine kinase activity
FIU16_02260	COG1114	Component of the transport system for branched-chain amino acids
FIU16_02265	COG1113	amino acid transport
FIU16_02270	COG0366	Alpha amylase catalytic
FIU16_02290	COG1862	Preprotein translocase
FIU16_02295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU16_02300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU16_02305	COG1403	HNH endonuclease
FIU16_02310	COG3248	Nucleoside-binding outer membrane protein
FIU16_02325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU16_02325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU16_02340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIU16_02345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU16_02350	COG0667	Aldo Keto reductase
FIU16_02360	COG0142	geranyltranstransferase activity
FIU16_02375	COG0693	protein deglycase activity
FIU16_02380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU16_02390	COG2814	Major facilitator Superfamily
FIU16_02415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIU16_02420	COG1845	cytochrome c oxidase, subunit III
FIU16_02425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU16_02430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU16_02435	COG2223	nitrite transmembrane transporter activity
FIU16_02440	COG3056	Lipoprotein
FIU16_02445	COG0271	Belongs to the BolA IbaG family
FIU16_02465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU16_02470	COG0776	regulation of translation
FIU16_02475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU16_02480	COG1555	photosystem II stabilization
FIU16_02485	COG0824	Thioesterase
FIU16_02495	COG4533	DNA binding
FIU16_02505	COG1522	sequence-specific DNA binding
FIU16_02510	COG1132	(ABC) transporter
FIU16_02515	COG1132	(ABC) transporter
FIU16_02520	COG0347	Belongs to the P(II) protein family
FIU16_02525	COG0004	ammonium transporteR
FIU16_02530	COG1946	Acyl-CoA thioesterase
FIU16_02535	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FIU16_02540	COG3695	enzyme binding
FIU16_02550	COG5507	3-demethylubiquinone-9 3-methyltransferase
FIU16_02555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIU16_02565	COG0110	maltose O-acetyltransferase activity
FIU16_02580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU16_02585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_02590	COG1309	transcriptional regulator
FIU16_02595	COG3264	Mechanosensitive ion channel
FIU16_02595	COG1196	nuclear chromosome segregation
FIU16_02605	COG3923	Primosomal replication protein n
FIU16_02610	COG2832	Protein of unknown function (DUF454)
FIU16_02620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIU16_02635	COG0326	Molecular chaperone. Has ATPase activity
FIU16_02660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_02665	COG4651	solute:proton antiporter activity
FIU16_02665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU16_02670	COG2223	nitrite transmembrane transporter activity
FIU16_02675	COG0737	Belongs to the 5'-nucleotidase family
FIU16_02680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU16_02685	COG3735	TraB family
FIU16_02695	COG3093	addiction module antidote protein HigA
FIU16_02700	COG2217	Heavy metal translocating P-type atpase
FIU16_02705	COG2066	Belongs to the glutaminase family
FIU16_02710	COG0531	amino acid
FIU16_02715	COG0789	Transcriptional regulator
FIU16_02720	COG1585	Membrane protein implicated in regulation of membrane protease activity
FIU16_02725	COG0330	HflC and HflK could
FIU16_02730	COG4619	ABC transporter
FIU16_02735	COG0390	transport system, permease component
FIU16_02740	COG3118	belongs to the thioredoxin family
FIU16_02745	COG0300	oxidoreductase activity
FIU16_02750	COG2755	lipolytic protein G-D-S-L family
FIU16_02755	COG4181	ATPase activity
FIU16_02760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU16_02765	COG3209	COG3209 Rhs family protein
FIU16_02775	COG3209	COG3209 Rhs family protein
FIU16_02795	COG0583	DNA-binding transcription factor activity
FIU16_02805	COG1414	Transcriptional regulator
FIU16_02810	COG3960	tartronate-semialdehyde synthase activity
FIU16_02815	COG3622	Belongs to the hyi family
FIU16_02820	COG2084	Dehydrogenase
FIU16_02825	COG1953	Uracil, thiamine, allantoin
FIU16_02835	COG2233	PERMEase
FIU16_02840	COG1929	Belongs to the glycerate kinase type-1 family
FIU16_02845	COG3257	ureidoglycine aminohydrolase activity
FIU16_02850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU16_02855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FIU16_02860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU16_02865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU16_02875	COG0549	Belongs to the carbamate kinase family
FIU16_02880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU16_02885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU16_02895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU16_02905	COG1988	membrane-bound metal-dependent
FIU16_02910	COG2501	S4 domain
FIU16_02920	COG3539	Fimbrial protein
FIU16_02925	COG3121	Chaperone
FIU16_02930	COG3188	usher protein
FIU16_02935	COG3539	Fimbrial protein
FIU16_02940	COG3539	Fimbrial protein
FIU16_02945	COG2197	response regulator
FIU16_02955	COG2207	Transcriptional regulator
FIU16_02965	COG4783	chaperone-mediated protein folding
FIU16_02970	COG1215	transferase activity, transferring glycosyl groups
FIU16_02975	COG5433	transposase activity
FIU16_02990	COG3209	COG3209 Rhs family protein
FIU16_02990	COG4104	PAAR repeat-containing protein
FIU16_03000	COG3501	Rhs element vgr protein
FIU16_03005	COG5002	protein histidine kinase activity
FIU16_03010	COG0745	RESPONSE REGULATOR receiver
FIU16_03015	COG1538	Outer membrane efflux protein
FIU16_03020	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_03025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_03030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU16_03035	COG1113	amino acid transport
FIU16_03040	COG0668	transmembrane transport
FIU16_03045	COG0778	Nitroreductase
FIU16_03050	COG2315	Protein conserved in bacteria
FIU16_03075	COG3385	transposase activity
FIU16_03090	COG3385	transposase activity
FIU16_03095	COG2977	Belongs to the P-Pant transferase superfamily
FIU16_03100	COG4771	TonB-dependent receptor
FIU16_03105	COG2382	esterase
FIU16_03110	COG3251	PFAM MbtH domain protein
FIU16_03115	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FIU16_03115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU16_03120	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FIU16_03125	COG1120	ATPase activity
FIU16_03130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU16_03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU16_03145	COG4592	Periplasmic binding protein
FIU16_03150	COG1169	isochorismate synthase
FIU16_03155	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIU16_03160	COG1535	isochorismatase
FIU16_03160	COG3433	isochorismatase activity
FIU16_03165	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_03170	COG2050	protein possibly involved in aromatic compounds catabolism
FIU16_03175	COG1966	Carbon starvation protein
FIU16_03180	COG2879	small protein
FIU16_03185	COG0371	Dehydrogenase
FIU16_03190	COG0436	Aminotransferase
FIU16_03195	COG1475	DNA binding
FIU16_03200	COG3969	phosphoadenosine phosphosulfate
FIU16_03205	COG0583	DNA-binding transcription factor activity
FIU16_03210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU16_03215	COG0450	alkyl hydroperoxide reductase
FIU16_03220	COG3634	alkyl hydroperoxide reductase activity
FIU16_03225	COG0589	response to stress
FIU16_03230	COG1063	alcohol dehydrogenase
FIU16_03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU16_03240	COG3719	Belongs to the RNase T2 family
FIU16_03245	COG0471	metal ion transport
FIU16_03260	COG3051	citrate lyase alpha subunit
FIU16_03265	COG2301	Belongs to the HpcH HpaI aldolase family
FIU16_03275	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FIU16_03280	COG3290	protein histidine kinase activity
FIU16_03285	COG4565	transcriptional regulatory protein
FIU16_03290	COG3069	C4-dicarboxylate transmembrane transporter activity
FIU16_03300	COG1278	Cold shock
FIU16_03310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU16_03315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU16_03325	COG0583	DNA-binding transcription factor activity
FIU16_03340	COG1686	Belongs to the peptidase S11 family
FIU16_03345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU16_03350	COG0772	Belongs to the SEDS family
FIU16_03355	COG0768	penicillin binding
FIU16_03365	COG0799	negative regulation of ribosome biogenesis
FIU16_03370	COG0406	alpha-ribazole phosphatase activity
FIU16_03380	COG1466	dna polymerase III delta subunit
FIU16_03395	COG2888	peptidyl-tyrosine sulfation
FIU16_03400	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIU16_03410	COG2214	Heat shock protein DnaJ domain protein
FIU16_03415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIU16_03425	COG2214	Heat shock protein DnaJ domain protein
FIU16_03430	COG0443	Heat shock 70 kDa protein
FIU16_03440	COG1126	abc transporter atp-binding protein
FIU16_03445	COG0765	amino acid transport
FIU16_03450	COG0765	amino acid transport
FIU16_03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_03470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU16_03475	COG4535	Mg2 and Co2 transporter CorC
FIU16_03485	COG1702	phosphate starvation-inducible protein PhoH
FIU16_03495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU16_03535	COG0367	asparagine synthase
FIU16_03540	COG0647	UMP catabolic process
FIU16_03545	COG1940	carbohydrate kinase activity
FIU16_03545	COG1846	Transcriptional regulator
FIU16_03550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU16_03560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_03560	COG1263	PTS System
FIU16_03560	COG2190	(PTS) system
FIU16_03580	COG0735	belongs to the Fur family
FIU16_03590	COG0716	FMN binding
FIU16_03600	COG0596	Alpha beta hydrolase
FIU16_03605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FIU16_03610	COG0033	Phosphoglucomutase
FIU16_03615	COG0531	amino acid
FIU16_03620	COG1982	Orn Lys Arg decarboxylase major
FIU16_03635	COG0745	RESPONSE REGULATOR receiver
FIU16_03640	COG2205	protein histidine kinase activity
FIU16_03670	COG3209	COG3209 Rhs family protein
FIU16_03700	COG3272	Protein of unknown function (DUF1722)
FIU16_03705	COG0415	Belongs to the DNA photolyase family
FIU16_03715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU16_03720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIU16_03725	COG1984	allophanate hydrolase subunit 2
FIU16_03740	COG3180	Ammonia monooxygenase
FIU16_03760	COG3539	Fimbrial protein
FIU16_03765	COG0372	Belongs to the citrate synthase family
FIU16_03775	COG2009	succinate dehydrogenase
FIU16_03780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIU16_03785	COG1053	succinate dehydrogenase
FIU16_03790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU16_03795	COG0567	Dehydrogenase, E1 component
FIU16_03800	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU16_03810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU16_03815	COG2188	Transcriptional regulator
FIU16_03820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_03820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_03820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_03825	COG0383	alpha-mannosidase activity
FIU16_03830	COG1271	oxidase subunit
FIU16_03835	COG1294	oxidase, subunit
FIU16_03840	COG4890	Cyd operon protein YbgT
FIU16_03845	COG3790	cyd operon protein YbgE
FIU16_03850	COG0824	Thioesterase
FIU16_03855	COG0811	peptide transport
FIU16_03860	COG0848	biopolymer transport protein
FIU16_03865	COG3064	Membrane
FIU16_03875	COG2885	chlorophyll binding
FIU16_03880	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FIU16_03930	COG3201	nicotinamide mononucleotide transporter
FIU16_03935	COG1230	cation diffusion facilitator family transporter
FIU16_03945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU16_03955	COG2017	converts alpha-aldose to the beta-anomer
FIU16_03965	COG1085	galactose-1-phosphate uridylyltransferase
FIU16_03970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU16_03975	COG1119	ATPase activity
FIU16_03980	COG2005	Transcriptional regulator
FIU16_03980	COG3585	molybdate ion transport
FIU16_03990	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU16_03995	COG4149	molybdate abc transporter
FIU16_04005	COG0561	phosphatase activity
FIU16_04015	COG0583	DNA-binding transcription factor activity
FIU16_04020	COG2828	Protein conserved in bacteria
FIU16_04025	COG0471	metal ion transport
FIU16_04030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIU16_04035	COG4677	pectinesterase activity
FIU16_04040	COG0582	viral genome integration into host DNA
FIU16_04145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU16_04205	COG3772	lysozyme
FIU16_04220	COG5562	phage envelope protein
FIU16_04235	COG4220	transposase activity
FIU16_04255	COG1030	water channel activity
FIU16_04305	COG1196	nuclear chromosome segregation
FIU16_04340	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_04345	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_04350	COG2199	diguanylate cyclase activity
FIU16_04355	COG1881	PFAM PEBP family protein
FIU16_04360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU16_04375	COG2226	methyltransferase
FIU16_04380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIU16_04390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FIU16_04400	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU16_04410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIU16_04415	COG0314	molybdopterin synthase activity
FIU16_04420	COG0670	Belongs to the BI1 family
FIU16_04430	COG0670	Belongs to the BI1 family
FIU16_04435	COG0392	lysyltransferase activity
FIU16_04440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU16_04445	COG3568	Endonuclease Exonuclease Phosphatase
FIU16_04455	COG0842	Transport permease protein
FIU16_04460	COG0842	Transport permease protein
FIU16_04465	COG1131	(ABC) transporter
FIU16_04475	COG1309	transcriptional regulator
FIU16_04480	COG0513	Belongs to the DEAD box helicase family
FIU16_04485	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FIU16_04490	COG1199	ATP-dependent helicase activity
FIU16_04495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU16_04500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FIU16_04510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU16_04520	COG4774	siderophore transport
FIU16_04535	COG0668	transmembrane transport
FIU16_04540	COG1126	abc transporter atp-binding protein
FIU16_04545	COG0765	amino acid transport
FIU16_04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_04560	COG5006	permease, DMT superfamily
FIU16_04570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU16_04575	COG2194	sulfuric ester hydrolase activity
FIU16_04585	COG1321	iron dependent repressor
FIU16_04590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU16_04595	COG1376	ErfK ybiS ycfS ynhG family protein
FIU16_04600	COG0488	(ABC) transporter
FIU16_04610	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_04620	COG0561	phosphatase activity
FIU16_04630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU16_04635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU16_04640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU16_04645	COG0303	'Molybdopterin
FIU16_04650	COG1446	asparaginase
FIU16_04670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU16_04675	COG2200	EAL domain
FIU16_04680	COG2199	diguanylate cyclase activity
FIU16_04695	COG2133	pyrroloquinoline quinone binding
FIU16_04700	COG0625	glutathione transferase activity
FIU16_04705	COG1686	Belongs to the peptidase S11 family
FIU16_04710	COG1349	DNA-binding transcription factor activity
FIU16_04715	COG0671	phosphoesterase, PA-phosphatase related
FIU16_04720	COG2814	Major facilitator Superfamily
FIU16_04730	COG0561	phosphatase activity
FIU16_04735	COG0738	Major facilitator superfamily
FIU16_04740	COG3226	Transcriptional regulator
FIU16_04755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU16_04765	COG0778	Nitroreductase
FIU16_04780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU16_04785	COG3842	ATPase activity
FIU16_04790	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU16_04795	COG1177	transmembrane transport
FIU16_04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_04815	COG4160	amino acid transport
FIU16_04820	COG4215	(ABC) transporter
FIU16_04825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_04830	COG1126	abc transporter atp-binding protein
FIU16_04845	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU16_04850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU16_04855	COG0702	epimerase
FIU16_04860	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FIU16_04865	COG0028	Belongs to the TPP enzyme family
FIU16_04870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU16_04880	COG2431	L-lysine efflux transmembrane transporter activity
FIU16_04885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU16_04890	COG3593	DNA synthesis involved in DNA repair
FIU16_04895	COG2990	Protein conserved in bacteria
FIU16_04900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_04910	COG1278	Cold shock
FIU16_04920	COG0542	response to heat
FIU16_04945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIU16_04950	COG4988	ABC transporter
FIU16_04955	COG0492	ferredoxin-NADP+ reductase activity
FIU16_04960	COG1522	sequence-specific DNA binding
FIU16_04975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU16_04985	COG0243	molybdopterin cofactor binding
FIU16_04990	COG0437	4 iron, 4 sulfur cluster binding
FIU16_04995	COG3302	dmso reductase anchor subunit
FIU16_05000	COG1335	isochorismatase
FIU16_05010	COG0531	amino acid
FIU16_05015	COG0583	DNA-binding transcription factor activity
FIU16_05020	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU16_05025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU16_05030	COG1882	Formate acetyltransferase
FIU16_05035	COG2116	formate transmembrane transporter activity
FIU16_05040	COG1944	ATP diphosphatase activity
FIU16_05045	COG2323	membrane
FIU16_05060	COG0501	Belongs to the peptidase M48B family
FIU16_05070	COG0539	negative regulation of cytoplasmic translation
FIU16_05080	COG2333	competence protein COMEC
FIU16_05080	COG0658	competence protein
FIU16_05085	COG1132	(ABC) transporter
FIU16_05095	COG3214	Protein conserved in bacteria
FIU16_05110	COG3173	Aminoglycoside phosphotransferase
FIU16_05115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIU16_05120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU16_05130	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FIU16_05140	COG2989	Protein conserved in bacteria
FIU16_05145	COG3108	Peptidase M15
FIU16_05150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU16_05155	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_05165	COG1448	Aminotransferase
FIU16_05170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU16_05185	COG0308	aminopeptidase N
FIU16_05195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU16_05205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU16_05210	COG0431	NADPH-dependent FMN reductase
FIU16_05215	COG3539	Fimbrial protein
FIU16_05220	COG3121	Chaperone
FIU16_05225	COG3188	usher protein
FIU16_05230	COG3539	Fimbrial protein
FIU16_05235	COG3539	Fimbrial protein
FIU16_05240	COG3539	Fimbrial protein
FIU16_05245	COG3121	Chaperone
FIU16_05260	COG0633	Ferredoxin
FIU16_05260	COG3217	Mosc domain protein beta barrel domain protein
FIU16_05270	COG0488	(ABC) transporter
FIU16_05275	COG2995	paraquat-inducible protein a
FIU16_05280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU16_05280	COG3008	intermembrane lipid transfer
FIU16_05285	COG3009	Protein conserved in bacteria
FIU16_05290	COG3130	regulation of translation
FIU16_05300	COG1067	ATP-dependent peptidase activity
FIU16_05310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU16_05310	COG2885	chlorophyll binding
FIU16_05320	COG3070	regulator of competence-specific genes
FIU16_05325	COG1289	transmembrane transporter activity
FIU16_05330	COG3304	Inner membrane component domain
FIU16_05335	COG0210	DNA helicase
FIU16_05350	COG1832	CoA-binding protein
FIU16_05365	COG1254	Belongs to the acylphosphatase family
FIU16_05370	COG2920	part of a sulfur-relay system
FIU16_05375	COG0670	Belongs to the BI1 family
FIU16_05385	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FIU16_05390	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FIU16_05395	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FIU16_05400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FIU16_05405	COG1999	signal sequence binding
FIU16_05410	COG1773	rubredoxin
FIU16_05415	COG1271	oxidase subunit
FIU16_05420	COG1294	oxidase, subunit
FIU16_05435	COG0489	protein tyrosine kinase activity
FIU16_05435	COG3206	protein involved in exopolysaccharide biosynthesis
FIU16_05440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU16_05445	COG1596	polysaccharide export
FIU16_05450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU16_05470	COG1278	Cold shock
FIU16_05475	COG1278	Cold shock
FIU16_05495	COG0348	domain, Protein
FIU16_05500	COG2205	protein histidine kinase activity
FIU16_05500	COG0784	Response regulator, receiver
FIU16_05500	COG2198	Histidine kinase
FIU16_05505	COG1879	ABC-type sugar transport system periplasmic component
FIU16_05510	COG0745	RESPONSE REGULATOR receiver
FIU16_05515	COG3005	denitrification pathway
FIU16_05520	COG0243	molybdopterin cofactor binding
FIU16_05560	COG0582	viral genome integration into host DNA
FIU16_05600	COG3561	AntA/AntB antirepressor
FIU16_05605	COG3561	AntA/AntB antirepressor
FIU16_05635	COG5532	Uncharacterized conserved protein (DUF2303)
FIU16_05675	COG3646	Phage regulatory protein
FIU16_05795	COG3772	lysozyme
FIU16_05870	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_05870	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_05950	COG3729	General stress protein
FIU16_05955	COG2233	PERMEase
FIU16_05990	COG1309	transcriptional regulator
FIU16_05995	COG0506	proline dehydrogenase activity
FIU16_05995	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU16_05995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU16_06005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU16_06010	COG0672	)-iron permease
FIU16_06015	COG2822	iron ion transport
FIU16_06020	COG2837	iron assimilation
FIU16_06025	COG1702	phosphate starvation-inducible protein PhoH
FIU16_06030	COG3658	cytochrome
FIU16_06035	COG1215	transferase activity, transferring glycosyl groups
FIU16_06040	COG0726	polysaccharide deacetylase
FIU16_06040	COG1649	PFAM Uncharacterised BCR, COG1649
FIU16_06045	COG0457	Tetratricopeptide repeat
FIU16_06050	COG3706	GGDEF domain
FIU16_06075	COG0582	viral genome integration into host DNA
FIU16_06115	COG3436	PFAM IS66 Orf2 family protein
FIU16_06130	COG4771	TonB-dependent receptor
FIU16_06195	COG3039	Transposase
FIU16_06220	COG2994	toxin metabolic process
FIU16_06315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU16_06325	COG0583	DNA-binding transcription factor activity
FIU16_06365	COG4245	von Willebrand factor, type A
FIU16_06370	COG4245	von Willebrand factor, type A
FIU16_06400	COG1358	cellular component organization or biogenesis
FIU16_06510	COG3436	PFAM IS66 Orf2 family protein
FIU16_06515	COG4372	Transposase
FIU16_06540	COG2003	Belongs to the UPF0758 family
FIU16_06590	COG3381	protein complex oligomerization
FIU16_06600	COG1462	curli production assembly transport component CsgG
FIU16_06615	COG2197	response regulator
FIU16_06640	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_06645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU16_06660	COG2943	transferase activity, transferring hexosyl groups
FIU16_06665	COG5645	(Lipo)protein
FIU16_06680	COG1560	Kdo2-lipid A biosynthetic process
FIU16_06690	COG2353	YceI-like domain
FIU16_06695	COG3038	cytochrome b561
FIU16_06730	COG2999	glutathione oxidoreductase activity
FIU16_06740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU16_06750	COG0673	inositol 2-dehydrogenase activity
FIU16_06755	COG0728	peptidoglycan biosynthetic process
FIU16_06760	COG3418	PFAM FlgN family protein
FIU16_06765	COG2747	anti-sigma28 factor FlgM
FIU16_06770	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FIU16_06775	COG1815	bacterial-type flagellum-dependent cell motility
FIU16_06780	COG1558	bacterial-type flagellum-dependent cell motility
FIU16_06785	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU16_06790	COG1749	Flagellar hook protein flgE
FIU16_06795	COG4787	bacterial-type flagellum-dependent cell motility
FIU16_06800	COG4786	Flagellar basal body rod
FIU16_06815	COG3951	Flagellar rod assembly protein muramidase FlgJ
FIU16_06815	COG1705	Flagellar rod assembly protein muramidase FlgJ
FIU16_06820	COG1256	bacterial-type flagellum assembly
FIU16_06825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU16_06830	COG1530	ribonuclease E activity
FIU16_06835	COG0564	pseudouridine synthase activity
FIU16_06845	COG1399	metal-binding, possibly nucleic acid-binding protein
FIU16_06865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU16_06870	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_06880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU16_06885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU16_06890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU16_06900	COG0470	DNA polymerase III
FIU16_06905	COG0084	hydrolase, TatD family'
FIU16_06910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_06910	COG1263	PTS System
FIU16_06915	COG4773	Receptor
FIU16_06920	COG0537	adenosine 5'-monophosphoramidase activity
FIU16_06925	COG5633	Lipoprotein
FIU16_06930	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FIU16_06950	COG1252	NADH dehydrogenase
FIU16_06955	COG3134	Outer membrane lipoprotein
FIU16_06960	COG1309	transcriptional regulator
FIU16_06970	COG1376	ErfK ybiS ycfS ynhG family protein
FIU16_06970	COG1388	LysM domain
FIU16_06975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU16_06980	COG4763	Acyl-transferase
FIU16_06985	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU16_06995	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU16_07005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU16_07010	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FIU16_07020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU16_07025	COG1177	transmembrane transport
FIU16_07030	COG0582	viral genome integration into host DNA
FIU16_07040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_07095	COG1846	Transcriptional regulator
FIU16_07180	COG1403	HNH endonuclease
FIU16_07185	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FIU16_07190	COG0484	heat shock protein binding
FIU16_07235	COG3772	lysozyme
FIU16_07265	COG4220	transposase activity
FIU16_07370	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_07375	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_07380	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU16_07385	COG3842	ATPase activity
FIU16_07395	COG2850	peptidyl-arginine hydroxylation
FIU16_07400	COG2205	protein histidine kinase activity
FIU16_07405	COG0745	RESPONSE REGULATOR receiver
FIU16_07410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU16_07430	COG1187	pseudouridine synthase activity
FIU16_07435	COG0538	isocitrate dehydrogenase activity
FIU16_07450	COG5562	phage envelope protein
FIU16_07455	COG0789	Transcriptional regulator
FIU16_07460	COG2200	EAL domain
FIU16_07485	COG2200	EAL domain
FIU16_07540	COG2894	cell division
FIU16_07565	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU16_07585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU16_07590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU16_07595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU16_07610	COG2719	SpoVR family
FIU16_07620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU16_07630	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU16_07640	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FIU16_07660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU16_07660	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FIU16_07660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_07665	COG1461	Dihydroxyacetone kinase
FIU16_07670	COG2376	Dihydroxyacetone kinase
FIU16_07675	COG3284	Transcriptional regulator
FIU16_07680	COG3468	outer membrane autotransporter barrel domain protein
FIU16_07685	COG0012	GTP binding
FIU16_07700	COG0659	secondary active sulfate transmembrane transporter activity
FIU16_07705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU16_07730	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU16_07735	COG3094	Invasion gene expression up-regulator, SirB
FIU16_07740	COG2912	Transglutaminase-like superfamily
FIU16_07780	COG0387	Pfam Sodium calcium exchanger
FIU16_07785	COG4572	Cation transport regulator
FIU16_07790	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FIU16_07795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FIU16_07800	COG4932	domain protein
FIU16_07805	COG2197	response regulator
FIU16_07810	COG3850	Histidine kinase
FIU16_07815	COG2223	nitrite transmembrane transporter activity
FIU16_07820	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FIU16_07825	COG1140	nitrate reductase beta subunit
FIU16_07830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FIU16_07835	COG2181	nitrate reductase activity
FIU16_07855	COG0788	formyltetrahydrofolate deformylase activity
FIU16_07865	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU16_07870	COG0745	RESPONSE REGULATOR receiver
FIU16_07875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU16_07880	COG2916	Histone family protein nucleoid-structuring protein H-NS
FIU16_07885	COG1435	thymidine kinase activity
FIU16_07895	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_07895	COG1454	alcohol dehydrogenase
FIU16_07900	COG2095	MarC family integral membrane protein
FIU16_07905	COG4166	transmembrane transport
FIU16_07910	COG0601	transmembrane transport
FIU16_07915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU16_07920	COG0444	Belongs to the ABC transporter superfamily
FIU16_07925	COG4608	Belongs to the ABC transporter superfamily
FIU16_07945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU16_07950	COG2350	Protein conserved in bacteria
FIU16_07955	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FIU16_07960	COG1607	acyl-coa hydrolase
FIU16_07980	COG3047	cAMP biosynthetic process
FIU16_07985	COG0582	viral genome integration into host DNA
FIU16_07995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_08040	COG1846	Transcriptional regulator
FIU16_08050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU16_08070	COG1403	HNH endonuclease
FIU16_08075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FIU16_08080	COG0484	heat shock protein binding
FIU16_08140	COG3772	lysozyme
FIU16_08185	COG4220	transposase activity
FIU16_08295	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_08300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_08310	COG0500	methyltransferase
FIU16_08325	COG3685	Protein conserved in bacteria
FIU16_08330	COG3685	Protein conserved in bacteria
FIU16_08335	COG3729	General stress protein
FIU16_08350	COG0134	indole-3-glycerol-phosphate synthase activity
FIU16_08350	COG0135	phosphoribosylanthranilate isomerase activity
FIU16_08355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU16_08355	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU16_08360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU16_08370	COG0613	PHP domain protein
FIU16_08375	COG0009	L-threonylcarbamoyladenylate synthase
FIU16_08380	COG1187	pseudouridine synthase activity
FIU16_08385	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FIU16_08390	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_08395	COG0616	signal peptide processing
FIU16_08405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU16_08410	COG0583	DNA-binding transcription factor activity
FIU16_08430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIU16_08440	COG0671	phosphoesterase, PA-phosphatase related
FIU16_08445	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FIU16_08450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIU16_08460	COG0023	Translation Initiation Factor
FIU16_08470	COG1349	DNA-binding transcription factor activity
FIU16_08480	COG5001	Diguanylate cyclase
FIU16_08495	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU16_08495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU16_08500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU16_08505	COG2852	Protein conserved in bacteria
FIU16_08510	COG4172	Belongs to the ABC transporter superfamily
FIU16_08515	COG4172	Belongs to the ABC transporter superfamily
FIU16_08520	COG4171	peptide transport system, permease
FIU16_08525	COG4168	peptide transport system, permease
FIU16_08530	COG4166	transmembrane transport
FIU16_08540	COG0531	amino acid
FIU16_08550	COG0174	glutamine synthetase
FIU16_08555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIU16_08560	COG1396	sequence-specific DNA binding
FIU16_08560	COG1917	Cupin 2, conserved barrel domain protein
FIU16_08565	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_08570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU16_08575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU16_08580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FIU16_08585	COG1842	Phage shock protein A
FIU16_08595	COG1983	PspC domain protein
FIU16_08605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU16_08610	COG0366	Alpha amylase catalytic
FIU16_08615	COG1653	transport
FIU16_08620	COG1175	transmembrane transport
FIU16_08625	COG0395	ABC-type sugar transport system, permease component
FIU16_08630	COG1063	alcohol dehydrogenase
FIU16_08635	COG1082	Xylose isomerase domain protein TIM barrel
FIU16_08640	COG0673	inositol 2-dehydrogenase activity
FIU16_08645	COG1554	hydrolase, family 65, central catalytic
FIU16_08650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU16_08655	COG3842	ATPase activity
FIU16_08665	COG1609	Transcriptional regulator
FIU16_08670	COG3106	COG3106 Predicted ATPase
FIU16_08680	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FIU16_08685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIU16_08690	COG4948	Mandelate Racemase Muconate Lactonizing
FIU16_08695	COG2866	Carboxypeptidase
FIU16_08710	COG1073	alpha beta
FIU16_08715	COG0583	DNA-binding transcription factor activity
FIU16_08720	COG4166	transmembrane transport
FIU16_08725	COG0668	transmembrane transport
FIU16_08730	COG3182	Iron-regulated membrane protein
FIU16_08735	COG0589	response to stress
FIU16_08740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU16_08745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU16_08750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU16_08755	COG1473	amidohydrolase
FIU16_08760	COG1473	amidohydrolase
FIU16_08765	COG0583	DNA-binding transcription factor activity
FIU16_08770	COG2840	Smr protein MutS2
FIU16_08775	COG3706	GGDEF domain
FIU16_08785	COG0513	Belongs to the DEAD box helicase family
FIU16_08795	COG0589	response to stress
FIU16_08800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU16_08805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FIU16_08805	COG0674	pyruvate-flavodoxin oxidoreductase activity
FIU16_08805	COG1013	pyruvate-flavodoxin oxidoreductase activity
FIU16_08805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU16_08810	COG3042	response to heat
FIU16_08815	COG3187	Heat shock protein
FIU16_08820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU16_08825	COG2911	Protein conserved in bacteria
FIU16_08835	COG3784	Protein of unknown function (DUF1318)
FIU16_08840	COG2207	Transcriptional regulator
FIU16_08845	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_08850	COG3733	amine oxidase
FIU16_08855	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_08855	COG2030	dehydratase
FIU16_08860	COG3396	Phenylacetate-CoA oxygenase
FIU16_08865	COG3460	Phenylacetate-CoA oxygenase
FIU16_08870	COG3396	Phenylacetate-CoA oxygenase
FIU16_08875	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU16_08880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU16_08885	COG1024	Enoyl-CoA hydratase
FIU16_08890	COG1024	Enoyl-CoA hydratase
FIU16_08895	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU16_08900	COG2050	protein possibly involved in aromatic compounds catabolism
FIU16_08905	COG0183	Belongs to the thiolase family
FIU16_08910	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FIU16_08915	COG3327	negative regulation of DNA-templated transcription, initiation
FIU16_08920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU16_08925	COG0667	Aldo Keto reductase
FIU16_08935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU16_08940	COG4589	Belongs to the CDS family
FIU16_08945	COG2267	carboxylic ester hydrolase activity
FIU16_08950	COG2453	phosphatase
FIU16_08950	COG0671	phosphoesterase, PA-phosphatase related
FIU16_08960	COG1643	Atp-dependent helicase
FIU16_08965	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIU16_08970	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_08975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU16_08980	COG3038	cytochrome b561
FIU16_08995	COG0840	transmembrane signaling receptor activity
FIU16_09000	COG0583	DNA-binding transcription factor activity
FIU16_09005	COG5383	Protein conserved in bacteria
FIU16_09015	COG2841	Protein conserved in bacteria
FIU16_09020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU16_09025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU16_09030	COG1275	C4-dicarboxylate transporter malic acid transport protein
FIU16_09035	COG0500	methyltransferase
FIU16_09050	COG0675	Transposase, IS605 OrfB family
FIU16_09055	COG3135	benzoate transporter
FIU16_09060	COG1396	sequence-specific DNA binding
FIU16_09065	COG0826	peptidase U32
FIU16_09080	COG1598	PFAM Uncharacterised protein family UPF0150
FIU16_09085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU16_09090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU16_09095	COG3842	ATPase activity
FIU16_09100	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU16_09105	COG1177	transmembrane transport
FIU16_09135	COG3238	Protein conserved in bacteria
FIU16_09140	COG1247	-acetyltransferase
FIU16_09145	COG2130	NADP-dependent
FIU16_09150	COG1802	Transcriptional regulator
FIU16_09155	COG4772	TonB-dependent receptor
FIU16_09160	COG3391	amine dehydrogenase activity
FIU16_09165	COG1113	amino acid transport
FIU16_09170	COG0625	glutathione transferase activity
FIU16_09180	COG3501	Rhs element vgr protein
FIU16_09185	COG3209	COG3209 Rhs family protein
FIU16_09205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU16_09210	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FIU16_09215	COG0384	phenazine biosynthesis protein PhzF
FIU16_09220	COG2181	nitrate reductase activity
FIU16_09225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FIU16_09230	COG1140	nitrate reductase beta subunit
FIU16_09235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FIU16_09240	COG2223	nitrite transmembrane transporter activity
FIU16_09245	COG4886	Leucine-rich repeat (LRR) protein
FIU16_09250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU16_09255	COG0697	spore germination
FIU16_09265	COG0437	4 iron, 4 sulfur cluster binding
FIU16_09270	COG2864	formate dehydrogenase
FIU16_09275	COG3093	addiction module antidote protein HigA
FIU16_09280	COG1064	alcohol dehydrogenase
FIU16_09300	COG1764	response to oxidative stress
FIU16_09305	COG4608	Belongs to the ABC transporter superfamily
FIU16_09310	COG0444	Belongs to the ABC transporter superfamily
FIU16_09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU16_09320	COG0601	transmembrane transport
FIU16_09325	COG0747	negative chemotaxis
FIU16_09330	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FIU16_09335	COG2202	Pas domain
FIU16_09335	COG2200	EAL domain
FIU16_09335	COG2199	diguanylate cyclase activity
FIU16_09350	COG0531	amino acid
FIU16_09355	COG0076	glutamate decarboxylase activity
FIU16_09360	COG0612	Peptidase, M16
FIU16_09365	COG4771	TonB-dependent receptor
FIU16_09370	COG4178	(ABC) transporter
FIU16_09380	COG0641	radical SAM
FIU16_09390	COG3039	Transposase
FIU16_09400	COG2207	Transcriptional regulator
FIU16_09410	COG0243	molybdopterin cofactor binding
FIU16_09415	COG3539	Fimbrial protein
FIU16_09420	COG3539	Fimbrial protein
FIU16_09425	COG3539	Fimbrial protein
FIU16_09430	COG3188	usher protein
FIU16_09435	COG3121	Chaperone
FIU16_09440	COG3539	Fimbrial protein
FIU16_09450	COG3550	peptidyl-serine autophosphorylation
FIU16_09455	COG1396	sequence-specific DNA binding
FIU16_09475	COG2390	Transcriptional regulator
FIU16_09495	COG1879	ABC-type sugar transport system periplasmic component
FIU16_09505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FIU16_09515	COG3781	membrane
FIU16_09525	COG2199	diguanylate cyclase activity
FIU16_09535	COG2066	Belongs to the glutaminase family
FIU16_09540	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_09545	COG0583	DNA-binding transcription factor activity
FIU16_09570	COG1846	Transcriptional regulator
FIU16_09575	COG4977	sequence-specific DNA binding
FIU16_09585	COG2723	6-phospho-beta-galactosidase activity
FIU16_09595	COG1447	Phosphotransferase system cellobiose-specific component IIA
FIU16_09600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FIU16_09610	COG2188	Transcriptional regulator
FIU16_09615	COG0697	spore germination
FIU16_09620	COG2814	Major facilitator Superfamily
FIU16_09630	COG3706	GGDEF domain
FIU16_09635	COG3111	PFAM Bacterial OB fold (BOF) protein
FIU16_09640	COG1546	Belongs to the CinA family
FIU16_09645	COG0339	signal peptide processing
FIU16_09650	COG4221	oxidoreductase activity
FIU16_09655	COG1802	Transcriptional regulator
FIU16_09665	COG0246	Mannitol dehydrogenase
FIU16_09670	COG0477	Major facilitator Superfamily
FIU16_09675	COG1063	alcohol dehydrogenase
FIU16_09680	COG4948	Mandelate Racemase Muconate Lactonizing
FIU16_09695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU16_09710	COG0243	molybdopterin cofactor binding
FIU16_09715	COG0243	molybdopterin cofactor binding
FIU16_09720	COG0437	4 iron, 4 sulfur cluster binding
FIU16_09725	COG3561	AntA/AntB antirepressor
FIU16_09910	COG3772	lysozyme
FIU16_10020	COG1846	Transcriptional regulator
FIU16_10025	COG1484	DNA-dependent DNA replication
FIU16_10095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_10125	COG0582	viral genome integration into host DNA
FIU16_10130	COG0437	4 iron, 4 sulfur cluster binding
FIU16_10135	COG3302	dmso reductase anchor subunit
FIU16_10140	COG3381	protein complex oligomerization
FIU16_10150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIU16_10155	COG1940	carbohydrate kinase activity
FIU16_10160	COG0583	DNA-binding transcription factor activity
FIU16_10165	COG2814	Major facilitator Superfamily
FIU16_10180	COG3591	Belongs to the peptidase S1B family
FIU16_10200	COG0628	permease
FIU16_10205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU16_10210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU16_10220	COG0531	amino acid
FIU16_10230	COG3136	membrane protein required for alginate biosynthesis
FIU16_10235	COG0745	RESPONSE REGULATOR receiver
FIU16_10240	COG2205	protein histidine kinase activity
FIU16_10250	COG0114	fumarate hydratase activity
FIU16_10255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU16_10255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU16_10260	COG1482	cell wall glycoprotein biosynthetic process
FIU16_10265	COG5339	Protein conserved in bacteria
FIU16_10280	COG3250	beta-galactosidase activity
FIU16_10285	COG1309	transcriptional regulator
FIU16_10290	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_10295	COG1609	Transcriptional regulator
FIU16_10300	COG1263	PTS System
FIU16_10300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_10305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU16_10315	COG0673	inositol 2-dehydrogenase activity
FIU16_10355	COG4659	FMN binding
FIU16_10365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU16_10370	COG3104	oligopeptide transport
FIU16_10375	COG0625	glutathione transferase activity
FIU16_10380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FIU16_10395	COG3895	Periplasmic Protein
FIU16_10405	COG3133	Outer membrane lipoprotein
FIU16_10420	COG1566	PFAM secretion protein HlyD family protein
FIU16_10425	COG1289	transmembrane transporter activity
FIU16_10430	COG2032	superoxide dismutase activity
FIU16_10435	COG4989	oxidoreductase activity
FIU16_10440	COG3313	Fe-S protein
FIU16_10445	COG1309	transcriptional regulator
FIU16_10450	COG1902	pentaerythritol trinitrate reductase activity
FIU16_10455	COG0346	lactoylglutathione lyase activity
FIU16_10465	COG1201	RNA secondary structure unwinding
FIU16_10470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU16_10475	COG0791	NLP P60 protein
FIU16_10480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIU16_10485	COG2814	Major facilitator Superfamily
FIU16_10500	COG0583	DNA-binding transcription factor activity
FIU16_10505	COG2814	Major facilitator Superfamily
FIU16_10510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU16_10515	COG0307	riboflavin synthase, alpha
FIU16_10525	COG3468	outer membrane autotransporter barrel domain protein
FIU16_10545	COG4529	Protein conserved in bacteria
FIU16_10555	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FIU16_10560	COG0437	4 iron, 4 sulfur cluster binding
FIU16_10570	COG2414	aldehyde ferredoxin oxidoreductase
FIU16_10575	COG0437	4 iron, 4 sulfur cluster binding
FIU16_10585	COG0469	pyruvate kinase activity
FIU16_10590	COG4238	major outer membrane lipoprotein
FIU16_10595	COG1376	ErfK ybiS ycfS ynhG family protein
FIU16_10610	COG0719	Fe-S assembly protein
FIU16_10615	COG0396	ATPase activity
FIU16_10620	COG0719	Fe-S assembly protein
FIU16_10625	COG0316	Belongs to the HesB IscA family
FIU16_10635	COG2050	protein possibly involved in aromatic compounds catabolism
FIU16_10640	COG0277	FAD linked oxidase domain protein
FIU16_10640	COG0247	lactate metabolic process
FIU16_10645	COG0628	permease
FIU16_10660	COG0738	Major facilitator superfamily
FIU16_10665	COG2271	Major facilitator Superfamily
FIU16_10680	COG4670	ketone body catabolic process
FIU16_10685	COG1960	acyl-CoA dehydrogenase activity
FIU16_10690	COG2207	Transcriptional regulator
FIU16_10690	COG1917	Cupin 2, conserved barrel domain protein
FIU16_10695	COG2086	electron transfer activity
FIU16_10700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIU16_10705	COG0644	oxidoreductase
FIU16_10710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FIU16_10715	COG0318	PFAM AMP-dependent synthetase and ligase
FIU16_10720	COG0574	Belongs to the PEP-utilizing enzyme family
FIU16_10720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU16_10730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU16_10735	COG4256	Hemin uptake protein
FIU16_10745	COG2200	EAL domain
FIU16_10750	COG0791	NLP P60 protein
FIU16_10760	COG0386	Belongs to the glutathione peroxidase family
FIU16_10775	COG4974	Belongs to the 'phage' integrase family
FIU16_10870	COG4695	Portal protein
FIU16_10955	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_10960	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_11075	COG3137	Salt-induced outer membrane protein
FIU16_11080	COG1105	Belongs to the carbohydrate kinase PfkB family
FIU16_11100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU16_11105	COG1988	membrane-bound metal-dependent
FIU16_11130	COG0753	catalase activity
FIU16_11140	COG1486	melibiose metabolic process
FIU16_11145	COG1917	Cupin 2, conserved barrel domain protein
FIU16_11145	COG2169	Transcriptional regulator
FIU16_11150	COG1447	Phosphotransferase system cellobiose-specific component IIA
FIU16_11155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FIU16_11160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FIU16_11165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU16_11175	COG0322	excinuclease ABC activity
FIU16_11185	COG3678	ATP-independent chaperone mediated protein folding
FIU16_11215	COG0708	Exodeoxyribonuclease III
FIU16_11220	COG0398	Pfam SNARE associated Golgi protein
FIU16_11230	COG0398	Pfam SNARE associated Golgi protein
FIU16_11235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU16_11240	COG4134	Bacterial extracellular solute-binding protein
FIU16_11245	COG4135	transport system, permease component
FIU16_11250	COG4136	ATPase activity
FIU16_11255	COG2897	thiosulfate sulfurtransferase activity
FIU16_11260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU16_11265	COG0494	nUDIX hydrolase
FIU16_11275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU16_11285	COG3039	Transposase
FIU16_11295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU16_11305	COG0778	Nitroreductase
FIU16_11310	COG0616	signal peptide processing
FIU16_11315	COG0252	asparaginase activity
FIU16_11320	COG1335	isochorismatase
FIU16_11325	COG2814	Major facilitator Superfamily
FIU16_11330	COG1349	DNA-binding transcription factor activity
FIU16_11335	COG0667	Aldo Keto reductase
FIU16_11340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_11345	COG0191	fructose-bisphosphate aldolase activity
FIU16_11350	COG1063	alcohol dehydrogenase
FIU16_11355	COG2271	Major facilitator Superfamily
FIU16_11360	COG1063	alcohol dehydrogenase
FIU16_11365	COG3139	Protein of unknown function (DUF1315)
FIU16_11375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU16_11380	COG0676	glucose-6-phosphate 1-epimerase activity
FIU16_11385	COG0656	L-ascorbic acid biosynthetic process
FIU16_11390	COG3713	MltA-interacting MipA family protein
FIU16_11395	COG2766	serine protein kinase
FIU16_11405	COG2199	diguanylate cyclase activity
FIU16_11410	COG2199	diguanylate cyclase activity
FIU16_11415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU16_11430	COG2207	Transcriptional regulator
FIU16_11435	COG2807	transmembrane transport
FIU16_11440	COG3189	MarR family transcriptional regulator
FIU16_11445	COG3042	response to heat
FIU16_11450	COG2199	diguanylate cyclase activity
FIU16_11450	COG2203	Gaf domain
FIU16_11465	COG2261	transglycosylase associated protein
FIU16_11470	COG0675	Transposase, IS605 OrfB family
FIU16_11475	COG1943	Transposase
FIU16_11485	COG0583	DNA-binding transcription factor activity
FIU16_11490	COG0473	3-isopropylmalate dehydrogenase activity
FIU16_11495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU16_11500	COG4638	Rieske (2fe-2S)
FIU16_11505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU16_11510	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU16_11515	COG0318	PFAM AMP-dependent synthetase and ligase
FIU16_11520	COG3065	identical protein binding
FIU16_11525	COG1214	PFAM Peptidase M22, glycoprotease
FIU16_11530	COG1199	ATP-dependent helicase activity
FIU16_11535	COG0251	oxidation-reduction process
FIU16_11550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU16_11560	COG1760	l-serine dehydratase
FIU16_11565	COG2200	EAL domain
FIU16_11570	COG1253	flavin adenine dinucleotide binding
FIU16_11575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_11575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_11580	COG3715	PTS system
FIU16_11585	COG3716	PTS system mannose fructose sorbose family IID component
FIU16_11600	COG2226	methyltransferase
FIU16_11605	COG1278	Cold shock
FIU16_11630	COG1414	Transcriptional regulator
FIU16_11635	COG2814	Major facilitator Superfamily
FIU16_11645	COG0793	Belongs to the peptidase S41A family
FIU16_11655	COG1956	GAF domain-containing protein
FIU16_11660	COG2995	paraquat-inducible protein a
FIU16_11665	COG3008	intermembrane lipid transfer
FIU16_11685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU16_11695	COG1276	copper resistance
FIU16_11700	COG2372	response to copper ion
FIU16_11710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU16_11715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_11720	COG1770	oligopeptidase
FIU16_11725	COG2979	Protein of unknown function (DUF533)
FIU16_11735	COG3141	response to X-ray
FIU16_11745	COG0800	Aldolase
FIU16_11750	COG0129	dihydroxy-acid dehydratase activity
FIU16_11755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU16_11760	COG1737	Transcriptional regulator
FIU16_11765	COG0469	pyruvate kinase activity
FIU16_11770	COG1560	Kdo2-lipid A biosynthetic process
FIU16_11775	COG0739	heme binding
FIU16_11780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIU16_11785	COG1121	(ABC) transporter
FIU16_11790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU16_11820	COG0217	transcriptional regulatory protein
FIU16_11825	COG0494	nUDIX hydrolase
FIU16_11835	COG1335	isochorismatase
FIU16_11855	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU16_11860	COG5301	cellulose 1,4-beta-cellobiosidase activity
FIU16_11895	COG1196	nuclear chromosome segregation
FIU16_11965	COG4220	transposase activity
FIU16_11985	COG3772	lysozyme
FIU16_12030	COG2207	Transcriptional regulator
FIU16_12055	COG1403	HNH endonuclease
FIU16_12065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FIU16_12070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU16_12075	COG4725	Belongs to the MT-A70-like family
FIU16_12085	COG1846	Transcriptional regulator
FIU16_12095	COG3646	Phage regulatory protein
FIU16_12135	COG5532	Uncharacterized conserved protein (DUF2303)
FIU16_12140	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU16_12195	COG0582	viral genome integration into host DNA
FIU16_12200	COG1801	Protein of unknown function DUF72
FIU16_12205	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FIU16_12220	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_12230	COG0243	molybdopterin cofactor binding
FIU16_12235	COG3005	denitrification pathway
FIU16_12245	COG3102	Protein conserved in bacteria
FIU16_12255	COG3755	Protein conserved in bacteria
FIU16_12265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU16_12270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU16_12275	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FIU16_12280	COG0745	RESPONSE REGULATOR receiver
FIU16_12285	COG2201	protein-glutamate methylesterase activity
FIU16_12290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU16_12295	COG0840	transmembrane signaling receptor activity
FIU16_12300	COG0840	transmembrane signaling receptor activity
FIU16_12305	COG0835	chemotaxis
FIU16_12310	COG2198	Histidine kinase
FIU16_12310	COG0643	Histidine kinase
FIU16_12315	COG1360	Flagellar Motor Protein
FIU16_12320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU16_12335	COG0589	response to stress
FIU16_12345	COG1877	trehalose-phosphatase activity
FIU16_12350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_12355	COG1129	ABC transporter
FIU16_12360	COG1879	ABC-type sugar transport system periplasmic component
FIU16_12365	COG1528	Iron-storage protein
FIU16_12390	COG1528	Iron-storage protein
FIU16_12400	COG0814	amino acid
FIU16_12405	COG3318	Belongs to the UPF0149 family
FIU16_12405	COG3012	SEC-C Motif Domain Protein
FIU16_12425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU16_12435	COG2197	response regulator
FIU16_12455	COG2197	response regulator
FIU16_12485	COG1191	sigma factor activity
FIU16_12490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU16_12495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU16_12500	COG1516	flagellar protein fliS
FIU16_12510	COG0366	Alpha amylase catalytic
FIU16_12520	COG2391	methyltransferase activity
FIU16_12525	COG0425	Belongs to the sulfur carrier protein TusA family
FIU16_12530	COG2135	peptidase activity
FIU16_12535	COG0675	Transposase, IS605 OrfB family
FIU16_12540	COG1943	Transposase
FIU16_12545	COG2207	Transcriptional regulator
FIU16_12550	COG1881	PFAM PEBP family protein
FIU16_12555	COG2076	Multidrug Resistance protein
FIU16_12570	COG1766	The M ring may be actively involved in energy transduction
FIU16_12575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU16_12580	COG1317	bacterial-type flagellum organization
FIU16_12585	COG1157	protein secretion by the type III secretion system
FIU16_12590	COG2882	bacterial-type flagellum organization
FIU16_12595	COG3144	bacterial-type flagellum assembly
FIU16_12600	COG1580	Controls the rotational direction of flagella during chemotaxis
FIU16_12605	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU16_12610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU16_12615	COG3190	flagellar
FIU16_12620	COG1338	Plays a role in the flagellum-specific transport system
FIU16_12625	COG1987	bacterial-type flagellum assembly
FIU16_12630	COG1684	flagellar biosynthetic protein fliR
FIU16_12635	COG2197	response regulator
FIU16_12665	COG5475	Uncharacterized small protein (DUF2158)
FIU16_12670	COG2354	Protein conserved in bacteria
FIU16_12675	COG0697	spore germination
FIU16_12680	COG3727	T/G mismatch-specific endonuclease activity
FIU16_12685	COG0270	DNA (cytosine-5-)-methyltransferase activity
FIU16_12690	COG1418	mRNA catabolic process
FIU16_12715	COG2826	transposase and inactivated derivatives, IS30 family
FIU16_12740	COG2205	protein histidine kinase activity
FIU16_12745	COG0745	RESPONSE REGULATOR receiver
FIU16_12750	COG2351	hydroxyisourate hydrolase activity
FIU16_12765	COG3443	Belongs to the bacterial solute-binding protein 9 family
FIU16_12785	COG0582	viral genome integration into host DNA
FIU16_12790	COG1169	isochorismate synthase
FIU16_12800	COG1132	(ABC) transporter
FIU16_12815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU16_12815	COG2226	methyltransferase
FIU16_12815	COG3433	isochorismatase activity
FIU16_12835	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIU16_12840	COG4771	TonB-dependent receptor
FIU16_12845	COG2373	Large extracellular alpha-helical protein
FIU16_12845	COG1388	LysM domain
FIU16_12845	COG4932	domain protein
FIU16_12850	COG1470	cell adhesion involved in biofilm formation
FIU16_12850	COG1388	LysM domain
FIU16_12855	COG1388	LysM domain
FIU16_12855	COG1470	cell adhesion involved in biofilm formation
FIU16_12860	COG1470	cell adhesion involved in biofilm formation
FIU16_12860	COG1388	LysM domain
FIU16_12870	COG0477	Major facilitator Superfamily
FIU16_12875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU16_12890	COG0534	Mate efflux family protein
FIU16_12900	COG0583	DNA-binding transcription factor activity
FIU16_12905	COG0583	DNA-binding transcription factor activity
FIU16_12915	COG1376	ErfK ybiS ycfS ynhG family protein
FIU16_12930	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FIU16_12950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_12965	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FIU16_13030	COG4372	Transposase
FIU16_13035	COG3436	PFAM IS66 Orf2 family protein
FIU16_13110	COG2003	Belongs to the UPF0758 family
FIU16_13140	COG4372	Transposase
FIU16_13145	COG4917	ethanolamine utilization protein
FIU16_13160	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_13165	COG1289	transmembrane transporter activity
FIU16_13170	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FIU16_13175	COG1686	Belongs to the peptidase S11 family
FIU16_13180	COG2925	Exonuclease
FIU16_13185	COG0425	Belongs to the sulfur carrier protein TusA family
FIU16_13190	COG2391	methyltransferase activity
FIU16_13195	COG0531	amino acid
FIU16_13205	COG0583	DNA-binding transcription factor activity
FIU16_13210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU16_13215	COG4115	mRNA cleavage
FIU16_13220	COG2161	toxin-antitoxin pair type II binding
FIU16_13235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU16_13245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU16_13245	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU16_13250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU16_13265	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU16_13265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU16_13275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU16_13280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU16_13320	COG2089	acid synthase
FIU16_13330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU16_13335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU16_13345	COG0438	transferase activity, transferring glycosyl groups
FIU16_13350	COG2327	Polysaccharide pyruvyl transferase
FIU16_13355	COG2244	polysaccharide biosynthetic process
FIU16_13360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU16_13365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU16_13370	COG0662	Cupin 2, conserved barrel domain protein
FIU16_13370	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FIU16_13375	COG0297	glycogen (starch) synthase activity
FIU16_13380	COG1051	belongs to the nudix hydrolase family
FIU16_13385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU16_13390	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FIU16_13395	COG0110	maltose O-acetyltransferase activity
FIU16_13400	COG1216	Glycosyl transferase, family 2
FIU16_13410	COG0438	transferase activity, transferring glycosyl groups
FIU16_13415	COG1045	serine acetyltransferase
FIU16_13420	COG0463	Glycosyl transferase, family 2
FIU16_13425	COG3206	protein involved in exopolysaccharide biosynthesis
FIU16_13425	COG0489	protein tyrosine kinase activity
FIU16_13430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU16_13435	COG1596	polysaccharide export
FIU16_13440	COG1253	flavin adenine dinucleotide binding
FIU16_13445	COG2982	Protein involved in outer membrane biogenesis
FIU16_13455	COG0572	uridine kinase
FIU16_13460	COG5002	protein histidine kinase activity
FIU16_13460	COG5001	Diguanylate cyclase
FIU16_13460	COG3447	MASE1 domain protein
FIU16_13465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIU16_13470	COG0443	Heat shock 70 kDa protein
FIU16_13475	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FIU16_13480	COG0631	protein serine/threonine phosphatase activity
FIU16_13485	COG4245	von Willebrand factor, type A
FIU16_13525	COG2205	protein histidine kinase activity
FIU16_13530	COG0745	RESPONSE REGULATOR receiver
FIU16_13540	COG3609	addiction module antidote protein, CC2985 family
FIU16_13570	COG1063	alcohol dehydrogenase
FIU16_13575	COG3775	system Galactitol-specific IIC component
FIU16_13580	COG3414	Phosphotransferase system galactitol-specific IIB component
FIU16_13585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_13605	COG1830	Aldolase
FIU16_13610	COG2211	Major facilitator Superfamily
FIU16_13615	COG1397	ADP-ribosylglycohydrolase
FIU16_13620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_13625	COG2188	Transcriptional regulator
FIU16_13630	COG3757	hydrolase, family 25
FIU16_13635	COG0351	phosphomethylpyrimidine kinase
FIU16_13655	COG5455	response to cobalt ion
FIU16_13675	COG3188	usher protein
FIU16_13680	COG3121	Chaperone
FIU16_13685	COG3539	Fimbrial protein
FIU16_13695	COG0489	protein tyrosine kinase activity
FIU16_13705	COG3831	ATPase activity
FIU16_13710	COG3831	ATPase activity
FIU16_13720	COG0714	Associated with various cellular activities
FIU16_13725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FIU16_13730	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FIU16_13735	COG4715	Zinc finger, swim domain protein
FIU16_13740	COG4808	Protein conserved in bacteria
FIU16_13745	COG4807	Protein conserved in bacteria
FIU16_13750	COG3279	Response regulator of the LytR AlgR family
FIU16_13755	COG3275	phosphorelay sensor kinase activity
FIU16_13760	COG0789	Transcriptional regulator
FIU16_13770	COG1174	glycine betaine transport
FIU16_13775	COG1125	glycine betaine transport
FIU16_13780	COG1174	glycine betaine transport
FIU16_13785	COG1732	Glycine betaine
FIU16_13790	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU16_13795	COG0277	FAD linked oxidase domain protein
FIU16_13800	COG1686	Belongs to the peptidase S11 family
FIU16_13810	COG0586	Pfam SNARE associated Golgi protein
FIU16_13815	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_13830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU16_13840	COG1346	cytolysis
FIU16_13850	COG2949	membrane
FIU16_13860	COG0493	'glutamate synthase
FIU16_13865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU16_13865	COG0167	dihydroorotate dehydrogenase activity
FIU16_13870	COG4211	Belongs to the binding-protein-dependent transport system permease family
FIU16_13875	COG1129	ABC transporter
FIU16_13880	COG1879	ABC-type sugar transport system periplasmic component
FIU16_13885	COG1609	Transcriptional regulator
FIU16_13890	COG2311	Membrane
FIU16_13905	COG4771	TonB-dependent receptor
FIU16_13910	COG0833	amino acid
FIU16_13915	COG0583	DNA-binding transcription factor activity
FIU16_13920	COG2855	membrane
FIU16_13930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_13930	COG1522	sequence-specific DNA binding
FIU16_13935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU16_13945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU16_13950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU16_13955	COG2313	pseudouridylate synthase activity
FIU16_13960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_13965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_13965	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIU16_13965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_13970	COG1105	Belongs to the carbohydrate kinase PfkB family
FIU16_13975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_13975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_13980	COG2814	Major facilitator Superfamily
FIU16_13995	COG0246	Mannitol dehydrogenase
FIU16_14000	COG0523	cobalamin synthesis protein
FIU16_14005	COG0671	phosphoesterase, PA-phosphatase related
FIU16_14010	COG0791	NLP P60 protein
FIU16_14015	COG2200	EAL domain
FIU16_14020	COG4166	transmembrane transport
FIU16_14025	COG4174	ABC transporter (Permease)
FIU16_14030	COG4239	(ABC) transporter, permease
FIU16_14035	COG4172	Belongs to the ABC transporter superfamily
FIU16_14045	COG2814	Major facilitator Superfamily
FIU16_14050	COG1187	pseudouridine synthase activity
FIU16_14055	COG1061	Type III restriction enzyme res subunit
FIU16_14075	COG3083	sulfuric ester hydrolase activity
FIU16_14090	COG2197	response regulator
FIU16_14095	COG4235	cytochrome complex assembly
FIU16_14095	COG3088	subunit of a heme lyase
FIU16_14100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU16_14105	COG1138	Cytochrome C-type biogenesis protein
FIU16_14115	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU16_14120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU16_14125	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU16_14135	COG3005	denitrification pathway
FIU16_14140	COG3043	anaerobic respiration
FIU16_14145	COG0348	domain, Protein
FIU16_14150	COG0437	4 iron, 4 sulfur cluster binding
FIU16_14160	COG3062	negative regulation of establishment of protein localization
FIU16_14165	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_14165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_14180	COG4615	Cyclic peptide transporter
FIU16_14185	COG3145	DNA-N1-methyladenine dioxygenase activity
FIU16_14190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU16_14190	COG2169	Transcriptional regulator
FIU16_14195	COG1477	protein flavinylation
FIU16_14200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU16_14205	COG2198	Histidine kinase
FIU16_14205	COG0642	Histidine kinase
FIU16_14210	COG2197	response regulator
FIU16_14215	COG0784	Response regulator, receiver
FIU16_14215	COG2205	protein histidine kinase activity
FIU16_14220	COG4676	Protein conserved in bacteria
FIU16_14225	COG5445	Predicted secreted protein (DUF2300)
FIU16_14230	COG2373	Large extracellular alpha-helical protein
FIU16_14235	COG3234	Protein of unknown function (DUF1175)
FIU16_14240	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
FIU16_14245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU16_14255	COG3468	outer membrane autotransporter barrel domain protein
FIU16_14260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU16_14265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU16_14270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU16_14275	COG3642	lipopolysaccharide core region biosynthetic process
FIU16_14280	COG3039	Transposase
FIU16_14290	COG0584	glycerophosphoryl diester phosphodiesterase
FIU16_14295	COG2271	Major facilitator Superfamily
FIU16_14300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU16_14310	COG0247	lactate metabolic process
FIU16_14315	COG5464	transposase or invertase
FIU16_14320	COG3836	Belongs to the HpcH HpaI aldolase family
FIU16_14385	COG0318	PFAM AMP-dependent synthetase and ligase
FIU16_14395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIU16_14410	COG1169	isochorismate synthase
FIU16_14415	COG4575	ribosome binding
FIU16_14420	COG2153	protein acetylation
FIU16_14450	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU16_14455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU16_14465	COG0839	Belongs to the complex I subunit 6 family
FIU16_14470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU16_14480	COG1034	ATP synthesis coupled electron transport
FIU16_14485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIU16_14490	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FIU16_14510	COG0583	DNA-binding transcription factor activity
FIU16_14515	COG0436	Aminotransferase
FIU16_14525	COG0490	domain, Protein
FIU16_14525	COG0471	metal ion transport
FIU16_14530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU16_14545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU16_14550	COG0280	phosphate acetyltransferase
FIU16_14550	COG0857	belongs to the CobB CobQ family
FIU16_14555	COG1288	antiporter activity
FIU16_14560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FIU16_14565	COG0622	Phosphoesterase
FIU16_14570	COG0625	glutathione transferase activity
FIU16_14575	COG0625	glutathione transferase activity
FIU16_14580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU16_14585	COG1090	epimerase
FIU16_14590	COG5464	transposase or invertase
FIU16_14595	COG4598	ABC transporter
FIU16_14600	COG4160	amino acid transport
FIU16_14605	COG4215	(ABC) transporter
FIU16_14610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_14620	COG0163	prenyltransferase activity
FIU16_14625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU16_14630	COG1286	toxin biosynthetic process
FIU16_14635	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FIU16_14640	COG0285	dihydrofolate synthase activity
FIU16_14650	COG0586	Pfam SNARE associated Golgi protein
FIU16_14660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU16_14675	COG2814	Major facilitator Superfamily
FIU16_14680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU16_14695	COG3101	peptidyl-lysine hydroxylation
FIU16_14700	COG0730	response to heat
FIU16_14725	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_14740	COG3539	Fimbrial protein
FIU16_14745	COG3539	Fimbrial protein
FIU16_14755	COG3539	Fimbrial protein
FIU16_14760	COG3121	Chaperone
FIU16_14765	COG3188	usher protein
FIU16_14770	COG3539	Fimbrial protein
FIU16_14775	COG2062	phosphohistidine phosphatase, SixA
FIU16_14790	COG3691	Protein conserved in bacteria
FIU16_14795	COG2067	long-chain fatty acid transport protein
FIU16_14805	COG2853	Lipoprotein
FIU16_14810	COG2116	formate transmembrane transporter activity
FIU16_14820	COG0582	viral genome integration into host DNA
FIU16_14915	COG1783	phage Terminase large subunit
FIU16_15000	COG3311	Transcriptional regulator
FIU16_15035	COG0477	Major facilitator Superfamily
FIU16_15040	COG1566	PFAM secretion protein HlyD family protein
FIU16_15045	COG2197	response regulator
FIU16_15050	COG0784	Response regulator, receiver
FIU16_15050	COG2198	Histidine kinase
FIU16_15050	COG2205	protein histidine kinase activity
FIU16_15050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_15055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU16_15060	COG0679	Auxin Efflux Carrier
FIU16_15065	COG0028	Belongs to the TPP enzyme family
FIU16_15090	COG1560	Kdo2-lipid A biosynthetic process
FIU16_15100	COG0436	Aminotransferase
FIU16_15105	COG3275	phosphorelay sensor kinase activity
FIU16_15110	COG3279	Response regulator of the LytR AlgR family
FIU16_15120	COG3039	Transposase
FIU16_15135	COG1363	Peptidase, m42
FIU16_15140	COG0006	proline dipeptidase activity
FIU16_15145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_15150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_15175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU16_15180	COG2199	diguanylate cyclase activity
FIU16_15180	COG2200	EAL domain
FIU16_15195	COG3415	Transposase
FIU16_15200	COG3415	Transposase
FIU16_15235	COG0583	DNA-binding transcription factor activity
FIU16_15245	COG2211	Major facilitator Superfamily
FIU16_15250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU16_15260	COG0583	DNA-binding transcription factor activity
FIU16_15265	COG0385	Bile acid
FIU16_15270	COG3530	Putative quorum-sensing-regulated virulence factor
FIU16_15290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU16_15295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_15300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU16_15305	COG2190	(PTS) system
FIU16_15320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU16_15325	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FIU16_15330	COG4208	sulfate ABC transporter
FIU16_15335	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FIU16_15340	COG4150	thiosulfate binding
FIU16_15345	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_15360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_15360	COG1263	PTS System
FIU16_15365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU16_15370	COG2837	iron assimilation
FIU16_15385	COG0456	acetyltransferase
FIU16_15390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU16_15400	COG2207	Transcriptional regulator
FIU16_15405	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIU16_15410	COG4816	utilization protein
FIU16_15420	COG4303	Ethanolamine ammonia lyase large subunit
FIU16_15425	COG4819	ethanolamine utilization protein
FIU16_15430	COG3192	ethanolamine utilization protein
FIU16_15435	COG1454	alcohol dehydrogenase
FIU16_15440	COG4820	ethanolamine utilization protein (EutJ)
FIU16_15445	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_15450	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FIU16_15455	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIU16_15460	COG0280	phosphate acetyltransferase
FIU16_15465	COG4812	Cobalamin adenosyltransferase
FIU16_15470	COG4766	ethanolamine catabolic process
FIU16_15475	COG4917	ethanolamine utilization protein
FIU16_15480	COG4810	utilization protein
FIU16_15485	COG0281	malic enzyme
FIU16_15485	COG0280	phosphate acetyltransferase
FIU16_15490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU16_15495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU16_15500	COG5342	invasion associated locus B
FIU16_15510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_15510	COG0493	'glutamate synthase
FIU16_15515	COG3850	Histidine kinase
FIU16_15520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU16_15530	COG1393	Belongs to the ArsC family
FIU16_15545	COG0400	carboxylic ester hydrolase activity
FIU16_15550	COG1444	tRNA N-acetyltransferase activity
FIU16_15555	COG2321	neutral zinc metallopeptidase
FIU16_15575	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FIU16_15585	COG2716	regulation of RNA biosynthetic process
FIU16_15590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU16_15595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_15600	COG0651	ATP synthesis coupled electron transport
FIU16_15615	COG4237	Hydrogenase 4 membrane
FIU16_15620	COG0651	ATP synthesis coupled electron transport
FIU16_15625	COG3261	NADH dehydrogenase
FIU16_15625	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FIU16_15630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU16_15635	COG3260	NADH ubiquinone oxidoreductase 20
FIU16_15645	COG3604	Transcriptional regulator
FIU16_15650	COG2116	formate transmembrane transporter activity
FIU16_15655	COG2116	formate transmembrane transporter activity
FIU16_15660	COG0628	permease
FIU16_15665	COG4783	chaperone-mediated protein folding
FIU16_15670	COG1393	Belongs to the ArsC family
FIU16_15680	COG2233	PERMEase
FIU16_15695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU16_15700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU16_15705	COG0248	Ppx GppA phosphatase
FIU16_15710	COG2200	EAL domain
FIU16_15720	COG3133	Outer membrane lipoprotein
FIU16_15735	COG0516	GMP reductase activity
FIU16_15735	COG0517	IMP dehydrogenase activity
FIU16_15745	COG1645	bacterial-type flagellum-dependent swarming motility
FIU16_15760	COG2976	Protein conserved in bacteria
FIU16_15790	COG4953	penicillin-binding protein 1C
FIU16_15795	COG2373	Large extracellular alpha-helical protein
FIU16_15800	COG2897	thiosulfate sulfurtransferase activity
FIU16_15815	COG2975	iron-sulfur cluster assembly
FIU16_15820	COG0633	Ferredoxin
FIU16_15840	COG0822	iron-sulfur transferase activity
FIU16_15860	COG0483	inositol monophosphate 1-phosphatase activity
FIU16_15865	COG1073	alpha beta
FIU16_15870	COG3711	transcriptional antiterminator
FIU16_15875	COG2814	Major facilitator Superfamily
FIU16_15880	COG0583	DNA-binding transcription factor activity
FIU16_15885	COG4638	Rieske (2fe-2S)
FIU16_15910	COG2259	Doxx family
FIU16_15915	COG2017	converts alpha-aldose to the beta-anomer
FIU16_15920	COG1063	alcohol dehydrogenase
FIU16_15925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_15930	COG1129	ABC transporter
FIU16_15935	COG1879	ABC-type sugar transport system periplasmic component
FIU16_15940	COG0457	Tetratricopeptide repeat
FIU16_15945	COG1940	carbohydrate kinase activity
FIU16_15955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU16_15955	COG1017	nitric oxide dioxygenase activity
FIU16_15960	COG0347	Belongs to the P(II) protein family
FIU16_15965	COG2204	response regulator
FIU16_15970	COG3170	Tfp pilus assembly protein FimV
FIU16_15975	COG2205	protein histidine kinase activity
FIU16_15980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU16_15980	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU16_15990	COG0590	tRNA wobble adenosine to inosine editing
FIU16_15995	COG0560	Phosphoserine phosphatase
FIU16_16000	COG1737	Transcriptional regulator
FIU16_16005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_16020	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU16_16040	COG0681	Belongs to the peptidase S26 family
FIU16_16050	COG3086	response to oxidative stress
FIU16_16055	COG3026	antisigma factor binding
FIU16_16060	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FIU16_16065	COG1595	DNA-templated transcription, initiation
FIU16_16075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIU16_16085	COG0513	Belongs to the DEAD box helicase family
FIU16_16090	COG0583	DNA-binding transcription factor activity
FIU16_16110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU16_16115	COG3118	belongs to the thioredoxin family
FIU16_16125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU16_16125	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU16_16125	COG1042	CoA-binding domain protein
FIU16_16130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU16_16135	COG5544	Lipoprotein
FIU16_16140	COG0477	Major facilitator Superfamily
FIU16_16165	COG0542	response to heat
FIU16_16175	COG0564	pseudouridine synthase activity
FIU16_16180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU16_16185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU16_16195	COG0077	Prephenate dehydratase
FIU16_16195	COG1605	Chorismate mutase
FIU16_16200	COG1605	Chorismate mutase
FIU16_16200	COG0287	Prephenate dehydrogenase
FIU16_16205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU16_16220	COG2199	diguanylate cyclase activity
FIU16_16225	COG2885	chlorophyll binding
FIU16_16250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU16_16255	COG4137	Cytochrome C assembly protein
FIU16_16260	COG4536	flavin adenine dinucleotide binding
FIU16_16275	COG0497	DNA recombination
FIU16_16280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU16_16285	COG2914	Belongs to the UPF0125 (RnfH) family
FIU16_16290	COG2867	negative regulation of translational initiation
FIU16_16305	COG0582	viral genome integration into host DNA
FIU16_16335	COG3311	Transcriptional regulator
FIU16_16340	COG3596	GTP binding
FIU16_16350	COG3468	outer membrane autotransporter barrel domain protein
FIU16_16385	COG0366	Alpha amylase catalytic
FIU16_16395	COG0579	oxidoreductase
FIU16_16400	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_16405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU16_16410	COG1113	amino acid transport
FIU16_16415	COG1802	Transcriptional regulator
FIU16_16420	COG1652	LysM domain
FIU16_16425	COG0401	homolog of Blt101
FIU16_16430	COG0640	Transcriptional regulator
FIU16_16435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU16_16440	COG2916	Histone family protein nucleoid-structuring protein H-NS
FIU16_16455	COG4575	ribosome binding
FIU16_16460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU16_16470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU16_16475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU16_16480	COG4175	Glycine betaine
FIU16_16485	COG4176	ABC-type proline glycine betaine transport system permease component
FIU16_16490	COG2113	Glycine betaine
FIU16_16495	COG2814	Major facilitator Superfamily
FIU16_16500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FIU16_16510	COG1846	Transcriptional regulator
FIU16_16515	COG1566	PFAM secretion protein HlyD family protein
FIU16_16520	COG2814	Major facilitator Superfamily
FIU16_16535	COG1238	metal cluster binding
FIU16_16540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU16_16590	COG1546	Belongs to the CinA family
FIU16_16595	COG2951	lytic endotransglycosylase activity
FIU16_16600	COG3730	PTS system glucitol sorbitol-specific
FIU16_16605	COG3732	PTS system glucitol sorbitol-specific
FIU16_16615	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_16620	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_16625	COG1349	DNA-binding transcription factor activity
FIU16_16630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU16_16630	COG0517	IMP dehydrogenase activity
FIU16_16650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FIU16_16655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_16660	COG1609	Transcriptional regulator
FIU16_16665	COG1263	PTS System
FIU16_16665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_16670	COG2723	6-phospho-beta-galactosidase activity
FIU16_16675	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_16685	COG5499	transcription regulator containing HTH domain
FIU16_16695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FIU16_16705	COG3260	NADH ubiquinone oxidoreductase 20
FIU16_16710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU16_16715	COG3261	NADH dehydrogenase
FIU16_16715	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FIU16_16720	COG0650	Formate hydrogenlyase subunit 4
FIU16_16725	COG0651	ATP synthesis coupled electron transport
FIU16_16730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_16745	COG0375	protein maturation
FIU16_16750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIU16_16755	COG0298	carbon dioxide binding
FIU16_16760	COG0409	Hydrogenase expression formation protein
FIU16_16765	COG0309	Hydrogenase expression formation protein (HypE)
FIU16_16770	COG3604	Transcriptional regulator
FIU16_16790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU16_16795	COG1349	DNA-binding transcription factor activity
FIU16_16800	COG2084	Dehydrogenase
FIU16_16805	COG3395	kinase activity
FIU16_16810	COG0235	Class ii aldolase
FIU16_16815	COG3622	Belongs to the hyi family
FIU16_16820	COG2610	gluconate transmembrane transporter activity
FIU16_16830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU16_16845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU16_16850	COG1388	LysM domain
FIU16_16850	COG4942	peptidase
FIU16_16905	COG2234	aminopeptidase activity
FIU16_16910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU16_16915	COG1518	maintenance of DNA repeat elements
FIU16_16930	COG1857	crispr-associated protein
FIU16_16945	COG1203	CRISPR-associated helicase, Cas3
FIU16_16950	COG3385	transposase activity
FIU16_16980	COG0720	synthase
FIU16_16985	COG0644	oxidoreductase
FIU16_16990	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FIU16_16995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FIU16_17000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIU16_17005	COG2086	electron transfer activity
FIU16_17010	COG0477	Major facilitator Superfamily
FIU16_17015	COG0277	FAD linked oxidase domain protein
FIU16_17020	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_17025	COG2223	nitrite transmembrane transporter activity
FIU16_17030	COG1070	Carbohydrate kinase
FIU16_17035	COG0602	queuosine metabolic process
FIU16_17060	COG3956	TIGRFAM MazG family protein
FIU16_17065	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIU16_17070	COG2336	PFAM SpoVT AbrB
FIU16_17075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU16_17085	COG3850	Histidine kinase
FIU16_17085	COG3437	response regulator, receiver
FIU16_17085	COG2205	protein histidine kinase activity
FIU16_17085	COG4999	Histidine kinase
FIU16_17090	COG4948	Mandelate Racemase Muconate Lactonizing
FIU16_17095	COG4948	Mandelate Racemase Muconate Lactonizing
FIU16_17105	COG2271	Major facilitator Superfamily
FIU16_17110	COG0716	FMN binding
FIU16_17120	COG3098	single-species biofilm formation
FIU16_17135	COG1611	Belongs to the LOG family
FIU16_17140	COG0814	amino acid
FIU16_17145	COG1760	l-serine dehydratase
FIU16_17155	COG1454	alcohol dehydrogenase
FIU16_17160	COG0235	Class ii aldolase
FIU16_17165	COG0738	Major facilitator superfamily
FIU16_17175	COG1070	Carbohydrate kinase
FIU16_17185	COG1349	DNA-binding transcription factor activity
FIU16_17195	COG2363	Small membrane protein
FIU16_17200	COG0583	DNA-binding transcription factor activity
FIU16_17210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU16_17215	COG2166	iron-sulfur cluster assembly
FIU16_17220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU16_17225	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIU16_17245	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU16_17250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU16_17250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIU16_17255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU16_17260	COG1074	ATP-dependent DNA helicase activity
FIU16_17265	COG1025	Belongs to the peptidase M16 family
FIU16_17270	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIU16_17275	COG4967	type IV pilus modification protein PilV
FIU16_17285	COG4795	General secretion pathway protein
FIU16_17290	COG2165	general secretion pathway protein
FIU16_17305	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FIU16_17325	COG0861	Integral membrane protein TerC family
FIU16_17335	COG0667	Aldo Keto reductase
FIU16_17355	COG1609	Transcriptional regulator
FIU16_17360	COG0019	diaminopimelate decarboxylase activity
FIU16_17365	COG0583	DNA-binding transcription factor activity
FIU16_17370	COG1794	racemase activity, acting on amino acids and derivatives
FIU16_17375	COG2814	Major facilitator Superfamily
FIU16_17380	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_17390	COG0183	Belongs to the thiolase family
FIU16_17395	COG0814	amino acid
FIU16_17400	COG2771	luxR family
FIU16_17405	COG3710	Transcriptional regulator
FIU16_17430	COG0457	Tetratricopeptide repeat
FIU16_17435	COG0457	Tetratricopeptide repeat
FIU16_17435	COG3710	Transcriptional regulator
FIU16_17540	COG3387	PFAM Glycoside hydrolase 15-related
FIU16_17550	COG4942	peptidase
FIU16_17555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU16_17560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU16_17565	COG2080	2 iron, 2 sulfur cluster binding
FIU16_17575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU16_17580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU16_17585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU16_17595	COG0549	Belongs to the carbamate kinase family
FIU16_17600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIU16_17600	COG3608	succinylglutamate desuccinylase aspartoacylase
FIU16_17605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU16_17610	COG2068	MobA-Related Protein
FIU16_17615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_17615	COG0493	'glutamate synthase
FIU16_17620	COG0402	S-adenosylhomocysteine deaminase activity
FIU16_17625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU16_17630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU16_17630	COG2080	2 iron, 2 sulfur cluster binding
FIU16_17635	COG2233	PERMEase
FIU16_17640	COG0402	S-adenosylhomocysteine deaminase activity
FIU16_17645	COG2252	PERMEase
FIU16_17650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_17660	COG2233	PERMEase
FIU16_17690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU16_17695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU16_17700	COG4974	Belongs to the 'phage' integrase family
FIU16_17705	COG0716	FMN binding
FIU16_17715	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIU16_17725	COG1272	protein, Hemolysin III
FIU16_17735	COG2723	6-phospho-beta-galactosidase activity
FIU16_17740	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_17765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU16_17770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU16_17775	COG0006	proline dipeptidase activity
FIU16_17795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU16_17810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU16_17830	COG1703	isobutyryl-CoA mutase activity
FIU16_17835	COG1024	Enoyl-CoA hydratase
FIU16_17840	COG0427	acetyl-CoA hydrolase
FIU16_17845	COG0583	DNA-binding transcription factor activity
FIU16_17850	COG2968	Membrane
FIU16_17855	COG1279	arginine transmembrane transporter activity
FIU16_17860	COG0668	transmembrane transport
FIU16_17865	COG0191	fructose-bisphosphate aldolase activity
FIU16_17895	COG1122	ATPase activity
FIU16_17900	COG1122	ATPase activity
FIU16_17905	COG1072	(Pantothenic acid kinase))
FIU16_17915	COG1494	fructose-1,6-bisphosphatase
FIU16_17920	COG1063	alcohol dehydrogenase
FIU16_17925	COG2213	PTS system mannitol-specific
FIU16_17930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_17935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU16_17940	COG0501	Belongs to the peptidase M48B family
FIU16_17955	COG1166	arginine decarboxylase activity
FIU16_17970	COG2814	Major facilitator Superfamily
FIU16_17980	COG2356	endonuclease I
FIU16_17985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU16_17990	COG0189	ligase activity
FIU16_18005	COG2805	Type II/IV secretion system protein
FIU16_18010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU16_18015	COG0762	integral membrane protein
FIU16_18025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU16_18030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU16_18040	COG0252	asparaginase activity
FIU16_18050	COG3171	Protein conserved in bacteria
FIU16_18060	COG1194	a g-specific adenine glycosylase
FIU16_18075	COG2211	Major facilitator Superfamily
FIU16_18080	COG1982	Orn Lys Arg decarboxylase major
FIU16_18085	COG1811	Na channel or pump
FIU16_18095	COG0582	viral genome integration into host DNA
FIU16_18125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU16_18130	COG0464	growth
FIU16_18135	COG1404	Belongs to the peptidase S8 family
FIU16_18140	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIU16_18155	COG2963	transposase activity
FIU16_18160	COG2826	transposase and inactivated derivatives, IS30 family
FIU16_18180	COG3344	reverse transcriptase
FIU16_18210	COG3436	PFAM IS66 Orf2 family protein
FIU16_18215	COG4372	Transposase
FIU16_18220	COG3039	Transposase
FIU16_18230	COG2801	Transposase and inactivated derivatives
FIU16_18235	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_18330	COG3501	Rhs element vgr protein
FIU16_18515	COG3468	outer membrane autotransporter barrel domain protein
FIU16_18520	COG2020	methyltransferase activity
FIU16_18555	COG2003	Belongs to the UPF0758 family
FIU16_18590	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIU16_18605	COG4795	General secretion pathway protein
FIU16_18620	COG2165	general secretion pathway protein
FIU16_18625	COG1459	type II secretion system
FIU16_18630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU16_18660	COG1620	l-lactate permease
FIU16_18665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU16_18670	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FIU16_18675	COG0247	lactate metabolic process
FIU16_18680	COG0277	FAD linked oxidase domain protein
FIU16_18685	COG0277	FAD linked oxidase domain protein
FIU16_18690	COG2186	Transcriptional regulator
FIU16_18695	COG0456	acetyltransferase
FIU16_18700	COG0318	PFAM AMP-dependent synthetase and ligase
FIU16_18710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU16_18715	COG0156	8-amino-7-oxononanoate synthase activity
FIU16_18725	COG0795	lipopolysaccharide-transporting ATPase activity
FIU16_18730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIU16_18740	COG2244	polysaccharide biosynthetic process
FIU16_18745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU16_18750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU16_18755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU16_18760	COG0306	phosphate transporter
FIU16_18765	COG0754	glutathionylspermidine amidase activity
FIU16_18770	COG0625	glutathione transferase activity
FIU16_18780	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_18785	COG0298	carbon dioxide binding
FIU16_18790	COG0375	protein maturation
FIU16_18795	COG1773	rubredoxin
FIU16_18800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FIU16_18805	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FIU16_18810	COG5557	Pfam Polysulphide reductase, NrfD
FIU16_18815	COG0437	4 iron, 4 sulfur cluster binding
FIU16_18820	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FIU16_18835	COG0667	Aldo Keto reductase
FIU16_18845	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_18850	COG0848	biopolymer transport protein
FIU16_18855	COG0811	peptide transport
FIU16_18860	COG0626	cystathionine gamma-synthase activity
FIU16_18865	COG0586	Pfam SNARE associated Golgi protein
FIU16_18870	COG2207	Transcriptional regulator
FIU16_18875	COG1979	alcohol dehydrogenase
FIU16_18880	COG0656	L-ascorbic acid biosynthetic process
FIU16_18890	COG4238	major outer membrane lipoprotein
FIU16_18895	COG1032	radical SAM domain protein
FIU16_18900	COG2132	Multicopper oxidase
FIU16_18905	COG0204	Acyl-transferase
FIU16_18910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU16_18915	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FIU16_18920	COG3111	PFAM Bacterial OB fold (BOF) protein
FIU16_18925	COG0745	RESPONSE REGULATOR receiver
FIU16_18930	COG0642	Histidine kinase
FIU16_18940	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU16_18945	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FIU16_18950	COG0187	DNA topoisomerase II activity
FIU16_18955	COG3150	esterase
FIU16_18960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU16_18965	COG3151	Protein conserved in bacteria
FIU16_18970	COG0494	nUDIX hydrolase
FIU16_18975	COG1538	Outer membrane efflux protein
FIU16_18985	COG0754	glutathionylspermidine amidase activity
FIU16_18990	COG3384	dioxygenase
FIU16_19005	COG2960	long-chain fatty acid transporting porin activity
FIU16_19010	COG3539	Fimbrial protein
FIU16_19015	COG3188	usher protein
FIU16_19020	COG3121	Chaperone
FIU16_19025	COG3539	Fimbrial protein
FIU16_19035	COG1585	Membrane protein implicated in regulation of membrane protease activity
FIU16_19040	COG2268	Band 7 protein
FIU16_19065	COG3025	triphosphatase activity
FIU16_19070	COG4991	sh3 domain protein
FIU16_19085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU16_19095	COG0583	DNA-binding transcription factor activity
FIU16_19110	COG0471	metal ion transport
FIU16_19125	COG0358	DNA primase activity
FIU16_19130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU16_19145	COG2375	cellular response to nickel ion
FIU16_19150	COG1695	Transcriptional regulator
FIU16_19155	COG0840	transmembrane signaling receptor activity
FIU16_19165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU16_19170	COG1609	Transcriptional regulator
FIU16_19175	COG3250	beta-galactosidase activity
FIU16_19180	COG2731	YhcH YjgK YiaL family protein
FIU16_19185	COG0531	amino acid
FIU16_19195	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FIU16_19195	COG3408	Glycogen debranching enzyme
FIU16_19200	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU16_19200	COG1902	pentaerythritol trinitrate reductase activity
FIU16_19205	COG5499	transcription regulator containing HTH domain
FIU16_19220	COG1451	nucleotide metabolic process
FIU16_19225	COG2949	membrane
FIU16_19230	COG0673	inositol 2-dehydrogenase activity
FIU16_19235	COG0861	Integral membrane protein TerC family
FIU16_19240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIU16_19250	COG2721	sulfolactate sulfo-lyase activity
FIU16_19260	COG2271	Major facilitator Superfamily
FIU16_19285	COG2186	Transcriptional regulator
FIU16_19290	COG0586	Pfam SNARE associated Golgi protein
FIU16_19300	COG1422	Protein of unknown function (DUF1090)
FIU16_19305	COG4575	ribosome binding
FIU16_19310	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FIU16_19320	COG2259	Doxx family
FIU16_19325	COG0435	Glutathione S-transferase
FIU16_19330	COG3152	Membrane
FIU16_19340	COG0583	DNA-binding transcription factor activity
FIU16_19345	COG1741	Belongs to the pirin family
FIU16_19360	COG0814	amino acid
FIU16_19365	COG1760	l-serine dehydratase
FIU16_19370	COG0251	oxidation-reduction process
FIU16_19375	COG1882	Formate acetyltransferase
FIU16_19380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU16_19390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU16_19395	COG0583	DNA-binding transcription factor activity
FIU16_19420	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_19430	COG1929	Belongs to the glycerate kinase type-1 family
FIU16_19435	COG2084	Dehydrogenase
FIU16_19445	COG2271	Major facilitator Superfamily
FIU16_19450	COG2721	sulfolactate sulfo-lyase activity
FIU16_19455	COG2002	toxin-antitoxin pair type II binding
FIU16_19465	COG1349	DNA-binding transcription factor activity
FIU16_19475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_19485	COG3716	PTS system mannose fructose sorbose family IID component
FIU16_19490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_19495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU16_19500	COG2222	sugar isomerase
FIU16_19510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_19515	COG3715	PTS system
FIU16_19520	COG3716	PTS system mannose fructose sorbose family IID component
FIU16_19525	COG0363	glucosamine-6-phosphate deaminase activity
FIU16_19530	COG3539	Fimbrial protein
FIU16_19535	COG3121	Chaperone
FIU16_19540	COG3188	usher protein
FIU16_19545	COG3539	Fimbrial protein
FIU16_19550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU16_19570	COG2823	Periplasmic or secreted lipoprotein
FIU16_19575	COG0701	Predicted permease
FIU16_19580	COG0702	epimerase
FIU16_19585	COG0693	protein deglycase activity
FIU16_19600	COG3153	acetyltransferase
FIU16_19620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU16_19625	COG0814	amino acid
FIU16_19630	COG0513	Belongs to the DEAD box helicase family
FIU16_19640	COG4785	May be involved in cell division
FIU16_19670	COG0195	Participates in both transcription termination and antitermination
FIU16_19690	COG2194	sulfuric ester hydrolase activity
FIU16_19700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU16_19710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU16_19715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU16_19725	COG1534	Rna-binding protein
FIU16_19730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU16_19735	COG2027	D-alanyl-D-alanine carboxypeptidase
FIU16_19745	COG0697	spore germination
FIU16_19760	COG0142	geranyltranstransferase activity
FIU16_19765	COG3423	Transcriptional regulator
FIU16_19775	COG5007	Belongs to the BolA IbaG family
FIU16_19780	COG3113	response to antibiotic
FIU16_19785	COG2854	intermembrane phospholipid transfer
FIU16_19790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU16_19795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU16_19800	COG1127	ABC transporter
FIU16_19805	COG0530	calcium, potassium:sodium antiporter activity
FIU16_19810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU16_19810	COG0517	IMP dehydrogenase activity
FIU16_19815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIU16_19820	COG3117	lipopolysaccharide transmembrane transporter activity
FIU16_19825	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FIU16_19830	COG1137	ATPase activity
FIU16_19835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FIU16_19840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU16_19845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_19855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_19860	COG0515	serine threonine protein kinase
FIU16_19870	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FIU16_19875	COG2198	Histidine kinase
FIU16_19875	COG0784	Response regulator, receiver
FIU16_19875	COG5002	protein histidine kinase activity
FIU16_19880	COG1242	4 iron, 4 sulfur cluster binding
FIU16_19885	COG0069	glutamate synthase activity
FIU16_19885	COG0070	glutamate synthase
FIU16_19885	COG0067	glutamate synthase
FIU16_19890	COG0493	'glutamate synthase
FIU16_19895	COG4804	nuclease activity
FIU16_19905	COG2731	YhcH YjgK YiaL family protein
FIU16_19935	COG3069	C4-dicarboxylate transmembrane transporter activity
FIU16_19940	COG2969	positive regulation of protein catabolic process
FIU16_19945	COG0625	glutathione transferase activity
FIU16_19965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU16_19970	COG3105	Protein conserved in bacteria
FIU16_19975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU16_19980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU16_20000	COG2732	(Barnase) inhibitor
FIU16_20020	COG0583	DNA-binding transcription factor activity
FIU16_20025	COG0312	modulator of DNA gyrase
FIU16_20030	COG3164	Protein of unknown function
FIU16_20035	COG1530	ribonuclease E activity
FIU16_20045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIU16_20050	COG1792	Involved in formation and maintenance of cell shape
FIU16_20055	COG1077	Cell shape determining protein MreB Mrl
FIU16_20060	COG2200	EAL domain
FIU16_20060	COG2199	diguanylate cyclase activity
FIU16_20065	COG0604	alcohol dehydrogenase
FIU16_20070	COG0511	ligase activity, forming carbon-carbon bonds
FIU16_20075	COG0439	Biotin carboxylase
FIU16_20080	COG3924	membrane
FIU16_20085	COG4145	pantothenate transmembrane transporter activity
FIU16_20095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU16_20105	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIU16_20115	COG1309	transcriptional regulator
FIU16_20120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_20125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU16_20135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU16_20140	COG4597	amino acid ABC transporter
FIU16_20145	COG0765	amino acid transport
FIU16_20150	COG1126	abc transporter atp-binding protein
FIU16_20195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU16_20215	COG0551	DNA topoisomerase type I activity
FIU16_20225	COG0758	DNA mediated transformation
FIU16_20245	COG0569	domain protein
FIU16_20255	COG3036	rescue of stalled ribosome
FIU16_20260	COG0789	Transcriptional regulator
FIU16_20290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU16_20300	COG0201	protein transport
FIU16_20390	COG0089	rRNA binding
FIU16_20420	COG2906	2 iron, 2 sulfur cluster binding
FIU16_20460	COG2964	Protein conserved in bacteria
FIU16_20465	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU16_20475	COG1047	Peptidyl-prolyl cis-trans
FIU16_20480	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FIU16_20495	COG0488	(ABC) transporter
FIU16_20500	COG0429	hydrolase of the alpha beta-hydrolase fold
FIU16_20510	COG3954	Phosphoribulokinase
FIU16_20515	COG1765	OsmC-like protein
FIU16_20520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU16_20525	COG1289	transmembrane transporter activity
FIU16_20530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU16_20535	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU16_20540	COG2184	nucleotidyltransferase activity
FIU16_20550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU16_20565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU16_20570	COG2146	nitrite reductase [NAD(P)H] activity
FIU16_20575	COG2116	formate transmembrane transporter activity
FIU16_20590	COG0531	amino acid
FIU16_20595	COG2222	sugar isomerase
FIU16_20600	COG1082	Xylose isomerase domain protein TIM barrel
FIU16_20605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_20610	COG2188	Transcriptional regulator
FIU16_20615	COG0626	cystathionine gamma-synthase activity
FIU16_20630	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FIU16_20635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIU16_20640	COG3457	Alanine racemase
FIU16_20650	COG2188	Transcriptional regulator
FIU16_20655	COG0180	Tryptophanyl-tRNA synthetase
FIU16_20665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIU16_20670	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FIU16_20675	COG3266	domain, Protein
FIU16_20690	COG4796	Type ii and iii secretion system protein
FIU16_20705	COG3166	PFAM Fimbrial assembly family protein
FIU16_20710	COG4972	Pilus assembly protein
FIU16_20715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU16_20720	COG0494	nUDIX hydrolase
FIU16_20730	COG1011	Hydrolase
FIU16_20735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU16_20745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FIU16_20765	COG2205	protein histidine kinase activity
FIU16_20770	COG0745	RESPONSE REGULATOR receiver
FIU16_20775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU16_20780	COG2183	response to ionizing radiation
FIU16_20785	COG1918	ferrous iron import across plasma membrane
FIU16_20790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FIU16_20800	COG5464	transposase or invertase
FIU16_20820	COG2610	gluconate transmembrane transporter activity
FIU16_20825	COG1640	4-alpha-glucanotransferase
FIU16_20830	COG0058	SHG alpha-glucan phosphorylase activity
FIU16_20845	COG1690	Belongs to the RtcB family
FIU16_20850	COG4650	regulator
FIU16_20855	COG1349	DNA-binding transcription factor activity
FIU16_20870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU16_20890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU16_20895	COG0058	SHG alpha-glucan phosphorylase activity
FIU16_20920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU16_20925	COG2095	MarC family integral membrane protein
FIU16_20930	COG2610	gluconate transmembrane transporter activity
FIU16_20935	COG3265	gluconokinase activity
FIU16_20940	COG1609	Transcriptional regulator
FIU16_20945	COG1741	Belongs to the pirin family
FIU16_20950	COG0673	inositol 2-dehydrogenase activity
FIU16_20955	COG1247	-acetyltransferase
FIU16_20960	COG3157	Type VI secretion system effector, Hcp
FIU16_20980	COG0405	Gamma-glutamyltransferase
FIU16_20990	COG0584	glycerophosphoryl diester phosphodiesterase
FIU16_20995	COG3842	ATPase activity
FIU16_21000	COG0395	ABC-type sugar transport system, permease component
FIU16_21005	COG1175	transmembrane transport
FIU16_21010	COG1653	transport
FIU16_21015	COG0410	ABC transporter
FIU16_21020	COG0411	ABC transporter
FIU16_21025	COG4177	L-phenylalanine transmembrane transporter activity
FIU16_21030	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU16_21035	COG0683	leucine binding
FIU16_21040	COG0456	acetyltransferase
FIU16_21045	COG0683	leucine binding
FIU16_21050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU16_21055	COG2177	Part of the ABC transporter FtsEX involved in
FIU16_21060	COG2884	Cell division ATP-binding protein ftsE
FIU16_21065	COG0552	protein localization to endoplasmic reticulum
FIU16_21070	COG0742	ribosomal rna small subunit methyltransferase
FIU16_21075	COG3776	membrane
FIU16_21085	COG3714	YhhN family
FIU16_21100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIU16_21115	COG0628	permease
FIU16_21120	COG2091	lysine biosynthetic process via aminoadipic acid
FIU16_21125	COG0747	negative chemotaxis
FIU16_21130	COG0601	transmembrane transport
FIU16_21135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU16_21140	COG0444	Belongs to the ABC transporter superfamily
FIU16_21165	COG0842	Transport permease protein
FIU16_21170	COG0842	Transport permease protein
FIU16_21170	COG1129	ABC transporter
FIU16_21175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_21210	COG2205	protein histidine kinase activity
FIU16_21215	COG0745	RESPONSE REGULATOR receiver
FIU16_21220	COG1276	copper resistance
FIU16_21225	COG2372	response to copper ion
FIU16_21230	COG3667	copper resistance
FIU16_21235	COG2132	Multicopper oxidase
FIU16_21245	COG0739	heme binding
FIU16_21275	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU16_21325	COG3436	PFAM IS66 Orf2 family protein
FIU16_21330	COG4372	Transposase
FIU16_21360	COG2081	HI0933 family
FIU16_21365	COG0306	phosphate transporter
FIU16_21375	COG0589	response to stress
FIU16_21385	COG3104	oligopeptide transport
FIU16_21395	COG0339	signal peptide processing
FIU16_21400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU16_21405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU16_21415	COG0640	Transcriptional regulator
FIU16_21420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU16_21425	COG1393	Belongs to the ArsC family
FIU16_21445	COG3065	identical protein binding
FIU16_21450	COG2197	response regulator
FIU16_21455	COG1285	pathogenesis
FIU16_21475	COG0076	glutamate decarboxylase activity
FIU16_21480	COG1858	cytochrome C peroxidase
FIU16_21490	COG2197	response regulator
FIU16_21495	COG0583	DNA-binding transcription factor activity
FIU16_21500	COG1295	ribonuclease BN
FIU16_21505	COG0477	Major facilitator Superfamily
FIU16_21510	COG2982	Protein involved in outer membrane biogenesis
FIU16_21515	COG2200	EAL domain
FIU16_21525	COG0612	Peptidase, M16
FIU16_21535	COG2199	diguanylate cyclase activity
FIU16_21535	COG2200	EAL domain
FIU16_21540	COG0457	Tetratricopeptide repeat
FIU16_21540	COG3118	belongs to the thioredoxin family
FIU16_21545	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FIU16_21550	COG1215	transferase activity, transferring glycosyl groups
FIU16_21555	COG1215	transferase activity, transferring glycosyl groups
FIU16_21580	COG2194	sulfuric ester hydrolase activity
FIU16_21625	COG0814	amino acid
FIU16_21630	COG4608	Belongs to the ABC transporter superfamily
FIU16_21635	COG0444	Belongs to the ABC transporter superfamily
FIU16_21640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU16_21645	COG0601	transmembrane transport
FIU16_21655	COG0747	negative chemotaxis
FIU16_21665	COG2194	sulfuric ester hydrolase activity
FIU16_21695	COG2223	nitrite transmembrane transporter activity
FIU16_21700	COG5571	outer membrane autotransporter
FIU16_21705	COG2818	Glycosylase
FIU16_21710	COG0456	acetyltransferase
FIU16_21715	COG0243	molybdopterin cofactor binding
FIU16_21720	COG2885	chlorophyll binding
FIU16_21735	COG2944	sequence-specific DNA binding
FIU16_21740	COG1278	Cold shock
FIU16_21765	COG3274	enterobacterial common antigen metabolic process
FIU16_21770	COG4682	membrane
FIU16_21775	COG4682	membrane
FIU16_21780	COG1070	Carbohydrate kinase
FIU16_21790	COG4213	ABC transporter substrate-binding protein
FIU16_21795	COG1129	ABC transporter
FIU16_21800	COG4214	carbohydrate transport
FIU16_21805	COG2207	Transcriptional regulator
FIU16_21805	COG1609	Transcriptional regulator
FIU16_21810	COG2992	FlgJ-related protein
FIU16_21820	COG3977	Valine--pyruvate aminotransferase
FIU16_21825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU16_21830	COG1414	Transcriptional regulator
FIU16_21840	COG2731	YhcH YjgK YiaL family protein
FIU16_21845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU16_21865	COG0235	Class ii aldolase
FIU16_21875	COG3713	MltA-interacting MipA family protein
FIU16_21880	COG0583	DNA-binding transcription factor activity
FIU16_21885	COG1566	PFAM secretion protein HlyD family protein
FIU16_21900	COG1012	belongs to the aldehyde dehydrogenase family
FIU16_21905	COG1454	alcohol dehydrogenase
FIU16_21910	COG3276	selenocysteine insertion sequence binding
FIU16_21920	COG0625	glutathione transferase activity
FIU16_21940	COG3209	COG3209 Rhs family protein
FIU16_21945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIU16_21965	COG1566	PFAM secretion protein HlyD family protein
FIU16_21975	COG2213	PTS system mannitol-specific
FIU16_21975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_21985	COG3722	fumarate hydratase activity
FIU16_22010	COG5295	Hep Hag repeat protein
FIU16_22015	COG1620	l-lactate permease
FIU16_22020	COG2186	Transcriptional regulator
FIU16_22030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU16_22035	COG1045	serine acetyltransferase
FIU16_22050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU16_22055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU16_22065	COG4942	peptidase
FIU16_22070	COG2861	carbohydrate metabolic process
FIU16_22075	COG1216	Glycosyl transferase, family 2
FIU16_22085	COG0156	8-amino-7-oxononanoate synthase activity
FIU16_22100	COG0859	PFAM glycosyl transferase family 9
FIU16_22105	COG0859	PFAM glycosyl transferase family 9
FIU16_22125	COG3642	lipopolysaccharide core region biosynthetic process
FIU16_22135	COG0515	serine threonine protein kinase
FIU16_22140	COG0438	transferase activity, transferring glycosyl groups
FIU16_22145	COG0859	PFAM glycosyl transferase family 9
FIU16_22150	COG1519	Transferase
FIU16_22180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU16_22205	COG1561	YicC-like family, N-terminal region
FIU16_22210	COG3645	SOS response
FIU16_22215	COG2860	membrane
FIU16_22235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU16_22240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU16_22245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU16_22250	COG0786	glutamate:sodium symporter activity
FIU16_22255	COG2233	PERMEase
FIU16_22260	COG2982	Protein involved in outer membrane biogenesis
FIU16_22265	COG1501	Belongs to the glycosyl hydrolase 31 family
FIU16_22270	COG2211	Major facilitator Superfamily
FIU16_22280	COG0582	viral genome integration into host DNA
FIU16_22305	COG3316	Transposase and inactivated derivatives
FIU16_22340	COG3316	Transposase and inactivated derivatives
FIU16_22370	COG3316	Transposase and inactivated derivatives
FIU16_22410	COG3316	Transposase and inactivated derivatives
FIU16_22500	COG3468	outer membrane autotransporter barrel domain protein
FIU16_22530	COG2003	Belongs to the UPF0758 family
FIU16_22570	COG2814	Major facilitator Superfamily
FIU16_22575	COG0697	spore germination
FIU16_22580	COG1464	Belongs to the NlpA lipoprotein family
FIU16_22600	COG2252	PERMEase
FIU16_22610	COG2271	Major facilitator Superfamily
FIU16_22615	COG2271	Major facilitator Superfamily
FIU16_22620	COG3851	Histidine kinase
FIU16_22625	COG2197	response regulator
FIU16_22630	COG0440	acetolactate synthase activity
FIU16_22635	COG0028	Belongs to the TPP enzyme family
FIU16_22650	COG2814	Major facilitator Superfamily
FIU16_22655	COG0641	radical SAM
FIU16_22665	COG2149	membrane
FIU16_22675	COG3119	arylsulfatase activity
FIU16_22680	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU16_22685	COG2207	Transcriptional regulator
FIU16_22695	COG2207	Transcriptional regulator
FIU16_22710	COG2188	Transcriptional regulator
FIU16_22730	COG5645	(Lipo)protein
FIU16_22735	COG0823	Involved in the tonB-independent uptake of proteins
FIU16_22745	COG2271	Major facilitator Superfamily
FIU16_22755	COG0800	Aldolase
FIU16_22760	COG3734	2-keto-3-deoxy-galactonokinase
FIU16_22765	COG2186	Transcriptional regulator
FIU16_22775	COG0561	phosphatase activity
FIU16_22780	COG3753	Protein conserved in bacteria
FIU16_22785	COG0187	DNA topoisomerase II activity
FIU16_22795	COG0592	DNA-directed DNA polymerase activity
FIU16_22845	COG0814	amino acid
FIU16_22860	COG2091	lysine biosynthetic process via aminoadipic acid
FIU16_22865	COG0431	NADPH-dependent FMN reductase
FIU16_22870	COG2252	PERMEase
FIU16_22875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU16_22885	COG3196	Protein conserved in bacteria
FIU16_22890	COG0363	glucosamine-6-phosphate deaminase activity
FIU16_22895	COG2382	esterase
FIU16_22905	COG2723	6-phospho-beta-galactosidase activity
FIU16_22910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_22910	COG1263	PTS System
FIU16_22910	COG2190	(PTS) system
FIU16_22920	COG0704	Plays a role in the regulation of phosphate uptake
FIU16_22925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU16_22930	COG0581	inorganic phosphate transmembrane transporter activity
FIU16_22935	COG0573	inorganic phosphate transmembrane transporter activity
FIU16_22940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU16_22950	COG3188	usher protein
FIU16_22955	COG3121	Chaperone
FIU16_22965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU16_23020	COG3312	ion transport
FIU16_23035	COG0716	FMN binding
FIU16_23040	COG1522	sequence-specific DNA binding
FIU16_23075	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_23080	COG1879	ABC-type sugar transport system periplasmic component
FIU16_23085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_23090	COG1609	Transcriptional regulator
FIU16_23095	COG0477	Major facilitator Superfamily
FIU16_23100	COG2186	Transcriptional regulator
FIU16_23140	COG3085	chromosome segregation
FIU16_23145	COG0606	chelatase, subunit chli
FIU16_23165	COG3978	acetolactate synthase activity
FIU16_23170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU16_23180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU16_23185	COG0583	DNA-binding transcription factor activity
FIU16_23195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU16_23200	COG3692	DNA binding
FIU16_23205	COG0210	DNA helicase
FIU16_23220	COG3118	belongs to the thioredoxin family
FIU16_23230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU16_23235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU16_23240	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FIU16_23245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIU16_23250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU16_23255	COG1088	dTDP-glucose 4,6-dehydratase activity
FIU16_23260	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FIU16_23265	COG0456	acetyltransferase
FIU16_23270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU16_23275	COG2244	polysaccharide biosynthetic process
FIU16_23295	COG1113	amino acid transport
FIU16_23320	COG0641	radical SAM
FIU16_23325	COG3071	HemY protein
FIU16_23330	COG2959	enzyme of heme biosynthesis
FIU16_23335	COG1587	Uroporphyrinogen-III synthase
FIU16_23345	COG3072	Adenylate cyclase
FIU16_23370	COG5567	small periplasmic lipoprotein
FIU16_23380	COG3159	Protein conserved in bacteria
FIU16_23390	COG1011	Hydrolase
FIU16_23395	COG0210	DNA helicase
FIU16_23400	COG3698	Phosphodiester glycosidase
FIU16_23405	COG0598	Magnesium transport protein CorA
FIU16_23420	COG0598	Magnesium transport protein CorA
FIU16_23435	COG2962	Rard protein
FIU16_23440	COG2050	protein possibly involved in aromatic compounds catabolism
FIU16_23445	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FIU16_23450	COG0514	ATP-dependent DNA helicase (RecQ)
FIU16_23455	COG1280	lysine exporter protein (LysE YggA)
FIU16_23460	COG1280	lysine exporter protein (LysE YggA)
FIU16_23465	COG2267	carboxylic ester hydrolase activity
FIU16_23470	COG0561	phosphatase activity
FIU16_23480	COG0583	DNA-binding transcription factor activity
FIU16_23490	COG0412	Dienelactone hydrolase
FIU16_23495	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FIU16_23500	COG1322	Protein conserved in bacteria
FIU16_23510	COG3165	ubiquinone biosynthetic process from chorismate
FIU16_23520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU16_23525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU16_23530	COG0805	protein transport
FIU16_23540	COG0250	Participates in transcription elongation, termination and antitermination
FIU16_23545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU16_23550	COG0543	2 iron, 2 sulfur cluster binding
FIU16_23570	COG1739	Uncharacterized protein family UPF0029
FIU16_23575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU16_23580	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FIU16_23610	COG1763	Mo-molybdopterin cofactor biosynthetic process
FIU16_23615	COG0746	molybdenum cofactor guanylyltransferase activity
FIU16_23620	COG3084	Protein conserved in bacteria
FIU16_23625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU16_23630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU16_23635	COG5339	Protein conserved in bacteria
FIU16_23640	COG0204	Acyl-transferase
FIU16_23650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU16_23650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU16_23665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU16_23675	COG2204	response regulator
FIU16_23680	COG3852	Histidine kinase
FIU16_23685	COG0174	glutamine synthetase
FIU16_23695	COG2188	Transcriptional regulator
FIU16_23700	COG1082	Xylose isomerase domain protein TIM barrel
FIU16_23705	COG2271	Major facilitator Superfamily
FIU16_23710	COG1349	DNA-binding transcription factor activity
FIU16_23715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_23720	COG2084	Dehydrogenase
FIU16_23725	COG3684	Belongs to the aldolase LacD family
FIU16_23730	COG1063	alcohol dehydrogenase
FIU16_23740	COG0477	Major facilitator Superfamily
FIU16_23750	COG1011	Hydrolase
FIU16_23765	COG0456	acetyltransferase
FIU16_23775	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FIU16_23785	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU16_23790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU16_23800	COG2864	formate dehydrogenase
FIU16_23805	COG0437	4 iron, 4 sulfur cluster binding
FIU16_23825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_23825	COG3711	transcriptional antiterminator
FIU16_23830	COG1363	Peptidase, m42
FIU16_23835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_23835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_23840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_23880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIU16_23890	COG2258	MOSC domain
FIU16_23895	COG2205	protein histidine kinase activity
FIU16_23900	COG0745	RESPONSE REGULATOR receiver
FIU16_23905	COG3678	ATP-independent chaperone mediated protein folding
FIU16_23920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FIU16_23940	COG3152	Membrane
FIU16_23945	COG3691	Protein conserved in bacteria
FIU16_23950	COG0589	response to stress
FIU16_23960	COG1494	fructose-1,6-bisphosphatase
FIU16_23970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU16_23985	COG1575	Belongs to the MenA family. Type 1 subfamily
FIU16_24000	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU16_24005	COG1609	Transcriptional regulator
FIU16_24010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU16_24020	COG3209	COG3209 Rhs family protein
FIU16_24045	COG0626	cystathionine gamma-synthase activity
FIU16_24050	COG0527	aspartate kinase activity
FIU16_24050	COG0460	homoserine dehydrogenase
FIU16_24055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU16_24060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU16_24065	COG0697	spore germination
FIU16_24070	COG3738	Protein conserved in bacteria
FIU16_24075	COG0371	Dehydrogenase
FIU16_24080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU16_24085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU16_24085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_24085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_24090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_24095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_24105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU16_24110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU16_24115	COG2207	Transcriptional regulator
FIU16_24120	COG2194	sulfuric ester hydrolase activity
FIU16_24135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU16_24140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU16_24155	COG4948	Mandelate Racemase Muconate Lactonizing
FIU16_24160	COG2271	Major facilitator Superfamily
FIU16_24165	COG0583	DNA-binding transcription factor activity
FIU16_24175	COG1309	transcriptional regulator
FIU16_24230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIU16_24230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIU16_24265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU16_24270	COG0250	Participates in transcription elongation, termination and antitermination
FIU16_24310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIU16_24320	COG2104	thiamine diphosphate biosynthetic process
FIU16_24325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU16_24360	COG3068	Protein conserved in bacteria
FIU16_24365	COG0776	regulation of translation
FIU16_24375	COG3678	ATP-independent chaperone mediated protein folding
FIU16_24380	COG4191	Histidine kinase
FIU16_24385	COG2204	response regulator
FIU16_24390	COG0151	Belongs to the GarS family
FIU16_24420	COG0456	acetyltransferase
FIU16_24430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU16_24435	COG2224	Isocitrate lyase
FIU16_24450	COG1414	Transcriptional regulator
FIU16_24455	COG0646	methionine synthase
FIU16_24455	COG1410	methionine synthase
FIU16_24460	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIU16_24470	COG1187	pseudouridine synthase activity
FIU16_24485	COG3541	Predicted nucleotidyltransferase
FIU16_24490	COG0542	response to heat
FIU16_24495	COG0527	aspartate kinase activity
FIU16_24520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU16_24535	COG0477	Major facilitator Superfamily
FIU16_24535	COG2814	Major facilitator Superfamily
FIU16_24540	COG3833	ABC-type maltose transport systems, permease component
FIU16_24545	COG1175	transmembrane transport
FIU16_24550	COG2182	Extracellular solute-binding protein
FIU16_24555	COG3842	ATPase activity
FIU16_24590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FIU16_24600	COG0534	Mate efflux family protein
FIU16_24605	COG3237	CsbD-like
FIU16_24610	COG0735	belongs to the Fur family
FIU16_24625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU16_24635	COG0604	alcohol dehydrogenase
FIU16_24640	COG0305	Participates in initiation and elongation during chromosome replication
FIU16_24645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU16_24650	COG1448	Aminotransferase
FIU16_24665	COG3700	Belongs to the class B bacterial acid phosphatase family
FIU16_24670	COG0432	Pfam Uncharacterised protein family UPF0047
FIU16_24675	COG2315	Protein conserved in bacteria
FIU16_24680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU16_24685	COG0629	single-stranded DNA binding
FIU16_24695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIU16_24700	COG2207	Transcriptional regulator
FIU16_24705	COG0789	Transcriptional regulator
FIU16_24710	COG2252	PERMEase
FIU16_24715	COG0025	NhaP-type Na H and K H
FIU16_24720	COG1357	PFAM Pentapeptide repeats (8 copies)
FIU16_24730	COG3162	membrane
FIU16_24735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU16_24745	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FIU16_24750	COG0437	4 iron, 4 sulfur cluster binding
FIU16_24755	COG3301	Polysulphide reductase, NrfD
FIU16_24760	COG1138	Cytochrome C-type biogenesis protein
FIU16_24765	COG3088	subunit of a heme lyase
FIU16_24770	COG4235	cytochrome complex assembly
FIU16_24775	COG1301	dicarboxylic acid transport
FIU16_24780	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIU16_24795	COG1289	transmembrane transporter activity
FIU16_24800	COG1566	PFAM secretion protein HlyD family protein
FIU16_24810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU16_24815	COG0698	ribose 5-phosphate isomerase
FIU16_24825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU16_24830	COG0456	acetyltransferase
FIU16_24835	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIU16_24840	COG3454	Phosphonate metabolism
FIU16_24845	COG4778	phosphonate C-P lyase system protein PhnL
FIU16_24850	COG4107	phosphonate C-P lyase system protein PhnK
FIU16_24855	COG3627	carbon phosphorus lyase activity
FIU16_24860	COG3626	phosphonate metabolism
FIU16_24865	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FIU16_24870	COG3624	Phosphonate C-P lyase system protein PhnG
FIU16_24875	COG2188	Transcriptional regulator
FIU16_24880	COG3639	organic phosphonate transmembrane transporter activity
FIU16_24885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIU16_24895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FIU16_24900	COG2824	Alkylphosphonate utilization operon protein PhnA
FIU16_24915	COG0477	Major facilitator Superfamily
FIU16_24925	COG0642	Histidine kinase
FIU16_24930	COG0745	RESPONSE REGULATOR receiver
FIU16_24935	COG2194	sulfuric ester hydrolase activity
FIU16_24940	COG0531	amino acid
FIU16_24945	COG2207	Transcriptional regulator
FIU16_24950	COG1982	Orn Lys Arg decarboxylase major
FIU16_24955	COG2169	Transcriptional regulator
FIU16_24960	COG1486	melibiose metabolic process
FIU16_24965	COG2211	Major facilitator Superfamily
FIU16_24970	COG3647	Membrane
FIU16_24975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU16_24975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU16_24980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU16_24985	COG4565	transcriptional regulatory protein
FIU16_24990	COG3290	protein histidine kinase activity
FIU16_24995	COG3592	Divergent 4Fe-4S mono-cluster
FIU16_25000	COG2388	GCN5-related N-acetyl-transferase
FIU16_25015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU16_25020	COG3104	oligopeptide transport
FIU16_25025	COG1982	Orn Lys Arg decarboxylase major
FIU16_25030	COG0531	amino acid
FIU16_25040	COG3710	Transcriptional regulator
FIU16_25075	COG2003	Belongs to the UPF0758 family
FIU16_25100	COG3344	reverse transcriptase
FIU16_25140	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_25195	COG3344	reverse transcriptase
FIU16_25240	COG3436	PFAM IS66 Orf2 family protein
FIU16_25245	COG4372	Transposase
FIU16_25255	COG3468	outer membrane autotransporter barrel domain protein
FIU16_25285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU16_25285	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FIU16_25290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU16_25290	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FIU16_25300	COG0582	viral genome integration into host DNA
FIU16_25310	COG1309	transcriptional regulator
FIU16_25325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU16_25330	COG1027	Aspartate ammonia-lyase
FIU16_25335	COG3030	protein affecting phage T7 exclusion by the F plasmid
FIU16_25340	COG0531	amino acid
FIU16_25365	COG1509	lysine 2,3-aminomutase activity
FIU16_25375	COG5510	response to toxic substance
FIU16_25380	COG5510	response to toxic substance
FIU16_25385	COG2076	Multidrug Resistance protein
FIU16_25390	COG3040	lipid binding
FIU16_25395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU16_25410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU16_25415	COG1053	succinate dehydrogenase
FIU16_25425	COG0531	amino acid
FIU16_25440	COG3264	Mechanosensitive ion channel
FIU16_25440	COG1511	domain protein
FIU16_25480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU16_25485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU16_25485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU16_25490	COG0802	atpase or kinase
FIU16_25495	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU16_25515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU16_25520	COG0330	HflC and HflK could
FIU16_25525	COG0330	HflC and HflK could
FIU16_25530	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FIU16_25545	COG0557	exoribonuclease II activity
FIU16_25550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU16_25555	COG3789	protein conserved in bacteria
FIU16_25560	COG1842	Phage shock protein A
FIU16_25575	COG5463	Belongs to the UPF0441 family
FIU16_25580	COG0754	glutathionylspermidine amidase activity
FIU16_25585	COG1960	acyl-CoA dehydrogenase activity
FIU16_25595	COG3650	response to hydrogen peroxide
FIU16_25600	COG1073	alpha beta
FIU16_25615	COG3037	sugar-specific permease SgaT UlaA
FIU16_25620	COG3414	Phosphotransferase system galactitol-specific IIB component
FIU16_25645	COG3477	response to acidic pH
FIU16_25685	COG1943	Transposase
FIU16_25690	COG0675	Transposase, IS605 OrfB family
FIU16_25700	COG3061	Opacity-associated protein A
FIU16_25710	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU16_25715	COG1113	amino acid transport
FIU16_25725	COG0697	spore germination
FIU16_25730	COG0702	epimerase
FIU16_25735	COG1733	regulation of RNA biosynthetic process
FIU16_25740	COG0737	Belongs to the 5'-nucleotidase family
FIU16_25745	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIU16_25750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIU16_25760	COG1253	flavin adenine dinucleotide binding
FIU16_25770	COG0729	surface antigen
FIU16_25775	COG2911	Protein conserved in bacteria
FIU16_25780	COG2105	PFAM AIG2 family protein
FIU16_25785	COG2336	PFAM SpoVT AbrB
FIU16_25790	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIU16_25795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIU16_25800	COG1879	ABC-type sugar transport system periplasmic component
FIU16_25805	COG1129	ABC transporter
FIU16_25810	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_25815	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU16_25825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU16_25835	COG0312	modulator of DNA gyrase
FIU16_25840	COG3783	Cytochrome b(562)
FIU16_25845	COG0602	queuosine metabolic process
FIU16_25850	COG1328	CTP reductase activity
FIU16_25860	COG0366	Alpha amylase catalytic
FIU16_25865	COG1263	PTS System
FIU16_25865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_25870	COG1609	Transcriptional regulator
FIU16_25880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIU16_25885	COG3547	Transposase (IS116 IS110 IS902 family)
FIU16_25895	COG0251	oxidation-reduction process
FIU16_25915	COG0251	oxidation-reduction process
FIU16_25920	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_25925	COG1309	transcriptional regulator
FIU16_25930	COG2731	YhcH YjgK YiaL family protein
FIU16_25960	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FIU16_25965	COG0456	acetyltransferase
FIU16_25970	COG4269	membrane
FIU16_25975	COG0525	valine-tRNA ligase activity
FIU16_25980	COG2927	DNA polymerase III (CHI subunit)
FIU16_25990	COG0795	lipopolysaccharide-transporting ATPase activity
FIU16_25995	COG0795	lipopolysaccharide-transporting ATPase activity
FIU16_26000	COG0433	COG0433 Predicted ATPase
FIU16_26005	COG1609	Transcriptional regulator
FIU16_26010	COG2610	gluconate transmembrane transporter activity
FIU16_26015	COG1028	Short-chain dehydrogenase reductase Sdr
FIU16_26020	COG1063	alcohol dehydrogenase
FIU16_26025	COG3265	gluconokinase activity
FIU16_26030	COG1064	alcohol dehydrogenase
FIU16_26085	COG3177	Filamentation induced by cAMP protein fic
FIU16_26100	COG1737	Transcriptional regulator
FIU16_26105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU16_26105	COG2190	(PTS) system
FIU16_26105	COG1263	PTS System
FIU16_26110	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FIU16_26120	COG1289	transmembrane transporter activity
FIU16_26140	COG1609	Transcriptional regulator
FIU16_26145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU16_26155	COG3037	sugar-specific permease SgaT UlaA
FIU16_26175	COG0738	Major facilitator superfamily
FIU16_26180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU16_26185	COG1349	DNA-binding transcription factor activity
FIU16_26190	COG0440	acetolactate synthase activity
FIU16_26205	COG4372	Transposase
FIU16_26210	COG3436	PFAM IS66 Orf2 family protein
FIU16_26220	COG0604	alcohol dehydrogenase
FIU16_26235	COG4325	translation initiation factor activity
FIU16_26245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU16_26260	COG2990	Protein conserved in bacteria
FIU16_26265	COG0297	glycogen (starch) synthase activity
FIU16_26270	COG0726	polysaccharide deacetylase
FIU16_26285	COG3344	reverse transcriptase
FIU16_26295	COG2085	NADP oxidoreductase coenzyme F420-dependent
FIU16_26300	COG1120	ATPase activity
FIU16_26305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU16_26310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU16_26315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FIU16_26320	COG4772	TonB-dependent receptor
FIU16_26325	COG3712	iron ion homeostasis
FIU16_26330	COG1595	DNA-templated transcription, initiation
FIU16_26360	COG4372	Transposase
FIU16_26365	COG3436	PFAM IS66 Orf2 family protein
FIU16_26455	COG2610	gluconate transmembrane transporter activity
FIU16_26465	COG0246	Mannitol dehydrogenase
FIU16_26470	COG2186	Transcriptional regulator
FIU16_26490	COG0583	DNA-binding transcription factor activity
FIU16_26495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU16_26500	COG0700	Nucleoside recognition
FIU16_26505	COG3366	ferrous iron transmembrane transporter activity
FIU16_26515	COG0477	Major facilitator Superfamily
FIU16_26530	COG1924	4 iron, 4 sulfur cluster binding
FIU16_26535	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FIU16_26540	COG2733	membrane
FIU16_26545	COG2814	Major facilitator Superfamily
FIU16_26555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU16_26560	COG5457	Domain of unknown function (DUF1127)
FIU16_26580	COG0732	type I restriction modification DNA specificity domain
FIU16_26600	COG0523	cobalamin synthesis protein
FIU16_26605	COG2879	small protein
FIU16_26610	COG1966	Carbon starvation protein
FIU16_26615	COG0840	transmembrane signaling receptor activity
FIU16_26620	COG2271	Major facilitator Superfamily
FIU16_26625	COG1802	Transcriptional regulator
FIU16_26630	COG1063	alcohol dehydrogenase
FIU16_26645	COG1484	DNA-dependent DNA replication
FIU16_26660	COG2966	Psort location CytoplasmicMembrane, score
FIU16_26665	COG2197	response regulator
FIU16_26670	COG2197	response regulator
FIU16_26675	COG4114	ferric iron reductase
FIU16_26705	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FIU16_26710	COG0456	acetyltransferase
FIU16_26715	COG1011	Hydrolase
FIU16_26725	COG2823	Periplasmic or secreted lipoprotein
FIU16_26735	COG4667	esterase of the alpha-beta hydrolase superfamily
FIU16_26740	COG0084	hydrolase, TatD family'
FIU16_26745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU16_26750	COG1328	CTP reductase activity
FIU16_26785	COG0560	Phosphoserine phosphatase
FIU16_26790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU16_26795	COG1056	cytidyltransferase-related domain
FIU16_26795	COG3172	ATPase kinase involved in NAD metabolism
FIU16_26800	COG0488	(ABC) transporter
FIU16_26805	COG0741	lytic transglycosylase activity
FIU16_26825	COG3708	Transcriptional regulator
FIU16_26825	COG2207	Transcriptional regulator
FIU16_26830	COG3045	CreA protein
FIU16_26835	COG0745	RESPONSE REGULATOR receiver
FIU16_26840	COG2205	protein histidine kinase activity
FIU16_26845	COG4452	Inner membrane protein CreD
FIU16_26850	COG0745	RESPONSE REGULATOR receiver
FIU16_26860	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FIU16_26870	COG0460	homoserine dehydrogenase
FIU16_26870	COG0527	aspartate kinase activity
FIU16_26880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIU16_26895	COG1115	amino acid carrier protein
FIU16_26905	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU16_26910	COG1584	GPR1 FUN34 yaaH family protein
FIU16_26915	COG4735	regulation of single-species biofilm formation
FIU16_26945	COG0583	DNA-binding transcription factor activity
FIU16_26975	COG0196	riboflavin kinase activity
FIU16_26990	COG1047	Peptidyl-prolyl cis-trans
FIU16_27010	COG0505	Belongs to the CarA family
FIU16_27015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU16_27065	COG0644	oxidoreductase
FIU16_27070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FIU16_27075	COG2271	Major facilitator Superfamily
FIU16_27090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIU16_27115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU16_27120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU16_27125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU16_27130	COG0564	pseudouridine synthase activity