locus-tag class description BA058_00030 ENOG4105GVR general secretion pathway protein D BA058_00030 ENOG4105GVR general secretion pathway protein D BA058_00080 ENOG4105CAF HipA N-terminal domain protein BA058_00085 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein BA058_00090 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) BA058_00095 ENOG4105FFC UPF0187 protein BA058_00105 ENOG4107QZW Altronate oxidoreductase BA058_00110 ENOG4105BZU Histidine kinase BA058_00115 ENOG4105M0C cytoplasmic protein BA058_00120 ENOG4105CSV Glutaminase BA058_00125 ENOG4105C26 Dehydrogenase BA058_00130 ENOG4105EGI Transcriptional regulator BA058_00135 ENOG4105F27 Major Facilitator BA058_00145 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BA058_00150 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF BA058_00155 ENOG4106DNR multiple antibiotic resistance protein BA058_00160 ENOG4105CS2 ec 3.2.1.21 BA058_00170 ENOG4105FDP GntR family transcriptional regulator BA058_00175 ENOG4108594 Permease of the drug metabolite transporter BA058_00180 ENOG4105E5W Transporter BA058_00190 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria BA058_00195 ENOG4108YDI single-species biofilm formation on inanimate substrate BA058_00200 ENOG4105DGW oligopeptidase A BA058_00205 ENOG4105EMU Dehydrogenase BA058_00210 ENOG4107XBN GntR Family Transcriptional Regulator BA058_00215 ENOG41061EV selenium-binding protein YdfZ BA058_00220 ENOG4105DEI Mannitol dehydrogenase BA058_00230 ENOG4105CPQ Dehydrogenase BA058_00235 ENOG4105CXK mandelate racemase muconate lactonizing BA058_00250 ENOG4108MK9 spermidine N(1)-acetyltransferase BA058_00260 ENOG4105KBG Protein of unknown function (DUF1161) BA058_00265 ENOG4108NEM leader-binding protein dmsD BA058_00275 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BA058_00280 ENOG4105DAG ROK family BA058_00285 ENOG4106NZI LysR family Transcriptional regulator BA058_00290 ENOG4105D94 Major Facilitator Superfamily BA058_00305 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BA058_00320 ENOG4105DSF transport protein BA058_00325 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BA058_00330 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BA058_00335 ENOG4105C5D exported protein BA058_00340 ENOG4105D5Q Arginine ornithine antiporter BA058_00345 ENOG410642E Short chain dehydrogenase BA058_00350 ENOG4105RA2 Membrane BA058_00355 ENOG4107EXC regulatoR BA058_00360 ENOG4105JJR Histidine kinase BA058_00365 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) BA058_00370 ENOG4105C9Q fumarate hydratase class II BA058_00375 ENOG4107GFK fumarate BA058_00380 ENOG4105EIP mannose-6-phosphate isomerase BA058_00385 ENOG4106J39 exported protein BA058_00390 ENOG4108QNI outer membrane porin protein BA058_00395 ENOG4105CT4 transporter BA058_00400 ENOG4105CNT hydrolase family 2 BA058_00405 ENOG4105XEA Tetr family transcriptional regulator BA058_00410 ENOG4107ZQV short-chain dehydrogenase reductase BA058_00415 ENOG4107P2S Transcriptional regulator BA058_00420 ENOG4105CI1 PTS System BA058_00425 ENOG4105C87 Aminotransferase class I and II BA058_00435 ENOG4105D9R oxidoreductase BA058_00440 ENOG4106C6R beta-lactam resistance protein BA058_00445 ENOG4105QZ5 OriC-binding nucleoid-associated protein BA058_00450 ENOG4105M9B inner membrane protein ydgK BA058_00465 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) BA058_00470 ENOG4105D6A Electron transport complex BA058_00475 ENOG4108UQQ Electron transport complex BA058_00485 ENOG4105CSM endonuclease III BA058_00495 ENOG4105DUX Transporter BA058_00500 ENOG4108K3A Glutathione S-transferase BA058_00505 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) BA058_00520 ENOG410642K Lysozyme inhibitor BA058_00525 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BA058_00530 ENOG4108XTF Outer Membrane Lipoprotein BA058_00545 ENOG4105Y49 secretion protein, HlyD family BA058_00550 ENOG4105DSW Fusaric acid resistance protein BA058_00555 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA058_00560 ENOG4107RGM aldo keto reductase BA058_00565 ENOG4105XZD Fe-S protein BA058_00570 ENOG4108WUH Transcriptional regulator, TetR family BA058_00575 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BA058_00580 ENOG4108UYE Lactoylglutathione lyase BA058_00595 ENOG4105M2J Glutaredoxin BA058_00600 ENOG4105K4H Nlp p60 protein BA058_00605 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA058_00610 ENOG4105F27 Major Facilitator BA058_00625 ENOG4105F52 Transcriptional regulator BA058_00630 ENOG4105CZQ inner membrane transport protein YdhC BA058_00635 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BA058_00640 ENOG4108R6K riboflavin synthase, subunit alpha BA058_00665 ENOG4105N0V mono-oxygenase ydhR BA058_00670 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain BA058_00675 ENOG4108Y7C Conserved Protein BA058_00680 ENOG4108NWD Cytochrome BA058_00685 ENOG4108393 oxidoreductase Fe-S subunit BA058_00690 ENOG4105JVW BA058_00695 ENOG4105WE2 aldehyde ferredoxin oxidoreductase BA058_00700 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein BA058_00705 ENOG4105RFR Protein of unknown function (DUF2767) BA058_00710 ENOG4105CA9 Pyruvate kinase BA058_00715 ENOG4105KMX major outer membrane lipoprotein BA058_00720 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA058_00725 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BA058_00730 ENOG4105C9B Cysteine desulfurase BA058_00735 ENOG4105JRK feS assembly protein SufD BA058_00740 ENOG4105C3K feS assembly ATPase SufC BA058_00745 ENOG4105DIW FeS assembly protein SUFB BA058_00750 ENOG4108Z4V iron-sulfur cluster assembly BA058_00755 ENOG410671Z uncharacterized protein ydiH BA058_00760 ENOG4105KA0 thioesterase Superfamily protein BA058_00765 ENOG4105CQB FAD linked oxidase domain protein BA058_00770 ENOG4105IPI Membrane BA058_00780 ENOG4105SUA Ydil protein BA058_00785 ENOG4105EMV Major Facilitator BA058_00790 ENOG4105EMV Major Facilitator BA058_00800 ENOG4105FF2 Type I DHQase BA058_00805 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) BA058_00810 ENOG4105C1G acyl-Coa dehydrogenase BA058_00815 ENOG4105W4W Transcriptional regulator BA058_00825 ENOG4105CV7 Electron transfer flavoprotein BA058_00830 ENOG4105C10 Electron transfer flavoprotein BA058_00835 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BA058_00840 ENOG41090P5 ferredoxin-like protein BA058_00845 ENOG4105CEY Amp-dependent synthetase and ligase BA058_00850 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BA058_00860 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BA058_00865 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BA058_00870 ENOG4106EDX Hemin uptake protein BA058_00875 ENOG4105CNG UPF0061 protein BA058_00880 ENOG4108TC0 Diguanylate phosphodiesterase BA058_00885 ENOG4108QBX (LipO)protein BA058_00895 ENOG4108V06 Glutathione peroxidase BA058_00900 ENOG4108ESU Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity) BA058_00925 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BA058_00930 ENOG41082NX 50s ribosomal protein l35 BA058_00955 ENOG4108NE3 Salt-induced outer membrane protein BA058_00960 ENOG4105DE4 1-phosphofructokinase BA058_00965 ENOG4105P10 Uncharacterized protein ydiZ BA058_00970 ENOG4105FGM Fructosamine kinase BA058_00975 ENOG4107PN8 YfeABCD locus regulator BA058_00980 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BA058_00985 ENOG4107K5X Membrane-bound metal-dependent hydrolase BA058_00990 ENOG4108ETY sodium dicarboxylate symporter BA058_01000 ENOG4105CH6 catalase BA058_01005 ENOG410901P UPF0249 protein BA058_01010 ENOG4105F8D glycoside hydrolase family 4 BA058_01015 ENOG4105EZV Transcriptional regulator BA058_01020 ENOG4105VCP PTS System BA058_01025 ENOG4105CK1 PTS System BA058_01030 ENOG4105VZJ PTS System BA058_01035 ENOG4105KKI DNA-binding transcriptional activator OsmE BA058_01040 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BA058_01050 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) BA058_01060 ENOG4108SPG Periplasmic Protein BA058_01065 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) BA058_01070 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) BA058_01075 ENOG4105C26 Dehydrogenase BA058_01080 ENOG4105F4X arginine BA058_01090 ENOG4105CGK Exodeoxyribonuclease III BA058_01095 ENOG4108RSN SNARE associated Golgi BA058_01100 ENOG4108KCW iron-sulfur cluster binding BA058_01105 ENOG4108N5C SNARE associated Golgi protein-related protein BA058_01110 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BA058_01115 ENOG4105VNH ABC transporter solute-binding protein BA058_01120 ENOG4105CXZ ABC transporter, permease BA058_01125 ENOG4108VGW abc transporter atp-binding protein BA058_01130 ENOG4107RM6 sulfurtransferase BA058_01135 ENOG4108T9J Cdp-alcohol phosphatidyltransferase BA058_01140 ENOG4105M6F mutator MutT protein BA058_01145 ENOG4105MTM Protein of unknown function (DUF1496) BA058_01150 ENOG4105D82 Glutamate dehydrogenase BA058_01165 ENOG4105F7F Chaperone BA058_01170 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BA058_01175 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) BA058_01185 ENOG41069NU Nitroreductase BA058_01195 ENOG4105D07 Signal peptide peptidase, SppA BA058_01200 ENOG4105HDK L-asparaginase BA058_01205 ENOG4108RWI nicotinamidase BA058_01210 ENOG4108KUU Inner membrane metabolite transport protein ydjE BA058_01215 ENOG4105E98 transcriptional regulator DeoR family BA058_01220 ENOG4105CPC Aldo Keto reductase BA058_01225 ENOG4107UH8 sugar kinase BA058_01230 ENOG4105D2N Aldolase BA058_01235 ENOG4105CPQ Dehydrogenase BA058_01240 ENOG4107TE1 transport protein BA058_01245 ENOG4105CPQ Dehydrogenase BA058_01250 ENOG4105VUT cytoplasmic protein BA058_01260 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BA058_01265 ENOG4105DSB aldose 1-epimerase BA058_01270 ENOG4105CV8 reductase BA058_01275 ENOG4105GNX MltA-interacting MipA family protein BA058_01280 ENOG4105CYN Serine protein kinase BA058_01290 ENOG4106KTS Inner membrane protein yeaI BA058_01295 ENOG4108KHP Diguanylate cyclase BA058_01300 ENOG4108KXH Ybak prolyl-tRNA synthetase associated BA058_01315 ENOG4105R1U AraC Family Transcriptional Regulator BA058_01320 ENOG4105DJ2 Major Facilitator Superfamily BA058_01325 ENOG4105K78 MarR family Transcriptional regulator BA058_01330 ENOG4105UCG Domain of unknown function (DUF333) BA058_01335 ENOG410620I Diguanylate cyclase BA058_01340 ENOG4106G4W BA058_01345 ENOG4105Y3U Transglycosylase-associated protein BA058_01350 ENOG4105YP6 Domain of unknown function (DUF1869) BA058_01355 ENOG4108YS1 cytoplasmic protein BA058_01370 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BA058_01375 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BA058_01380 ENOG4105CEY Amp-dependent synthetase and ligase BA058_01385 ENOG4105Y4Z Outer Membrane Lipoprotein BA058_01390 ENOG41072GX Peptidase M22 Glycoprotease BA058_01395 ENOG4105DVT helicase BA058_01400 ENOG4105M4H endoribonuclease L-psp BA058_01410 ENOG4105V2F Uncharacterized protein yoac BA058_01420 ENOG4105CRQ synthase (Component I) BA058_01430 ENOG4105EJQ L-serine dehydratase BA058_01435 ENOG4107XTP (EAL) domain protein BA058_01440 ENOG4105EE5 Membrane protein terC BA058_01450 ENOG4108EQA pts system BA058_01455 ENOG4105ETZ PTS System BA058_01460 ENOG4105F3R pts system mannose fructose sorbose family iid BA058_01480 ENOG4105DHI Methyltransferase BA058_01485 ENOG4105VEQ Cold shock protein BA058_01490 ENOG410610J Protein of unknown function (DUF2627) BA058_01500 ENOG4105Q3Y exported protein BA058_01510 ENOG4105TIK BA058_01515 ENOG4105J4Q Transcriptional regulator BA058_01520 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA058_01530 ENOG4105CN1 protease BA058_01540 ENOG4108ZGC gaf domain protein BA058_01545 ENOG4105H2K paraquat-inducible protein a BA058_01550 ENOG4105DY2 Paraquat-inducible protein b BA058_01555 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BA058_01560 ENOG4105WT8 Protein of unknown function (DUF1480) BA058_01565 ENOG4105UVW uncharacterized protein yebW BA058_01570 ENOG4108R1E Serine threonine protein phosphatase 1 BA058_01580 ENOG4105NKT exported protein BA058_01585 ENOG4108PNC copper resistance BA058_01590 ENOG4105FXM Copper resistance protein BA058_01595 ENOG4105MPK DNA polymerase III subunit theta BA058_01600 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BA058_01605 ENOG4105UMD exodeoxyribonuclease X BA058_01610 ENOG4105CUG Oligopeptidase b BA058_01615 ENOG4108Q2J Inner membrane protein YebE BA058_01625 ENOG4105RSZ secreted protein BA058_01630 ENOG4105X2V dna damage-inducible protein BA058_01640 ENOG4108UHU Aldolase BA058_01645 ENOG4105C01 Dihydroxy-acid dehydratase BA058_01650 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BA058_01660 ENOG4106KNT transcriptional regulator BA058_01665 ENOG4105CA9 Pyruvate kinase BA058_01670 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BA058_01675 ENOG4105DR5 peptidase BA058_01680 ENOG4105NXV High-affinity zinc uptake system protein BA058_01685 ENOG4105FDK ABC transporter BA058_01690 ENOG4105FAV ABC, transporter BA058_01705 ENOG4107S01 Repressor protein MetJ BA058_01715 ENOG4105CDY transcriptional regulatory protein BA058_01720 ENOG4108TIT dATP pyrophosphohydrolase BA058_01730 ENOG4105D3W isochorismatase BA058_01735 ENOG41081XQ Conserved Protein BA058_01740 ENOG4105WJG Glutathione BA058_01750 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BA058_01755 ENOG4108J2R molybdopterin oxidoreductase BA058_01760 ENOG4105CUW cytochrome C-TYPE protein BA058_01770 ENOG4106ZCM YecM protein BA058_01775 ENOG4105C75 arginyL-tRNA synthetase BA058_01780 ENOG4105W13 flagellar protein BA058_01785 ENOG4105D7B Flagellar biosynthesis protein flha BA058_01790 ENOG4105D00 flagellar biosynthetic protein flhB BA058_01795 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BA058_01800 ENOG4108VYJ response regulator receiver protein BA058_01805 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BA058_01810 ENOG4105BZU Histidine kinase BA058_01815 ENOG4105C8Q Methyl-accepting chemotaxis BA058_01820 ENOG4108V3W Chemotaxis protein, CheW BA058_01825 ENOG4105CBS Chea signal transduction histidine kinase BA058_01830 ENOG4105ER2 Ompa motb domain protein BA058_01835 ENOG4107RD7 Flagellar Motor Protein, MotA BA058_01840 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BA058_01850 ENOG4108VA4 Universal stress protein BA058_01855 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase BA058_01860 ENOG4108K4C ec 3.1.3.12 BA058_01865 ENOG4105CNN ABC, transporter BA058_01870 ENOG4105C2J ABC transporter BA058_01875 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BA058_01880 ENOG4108UEC Ferritin-like protein BA058_01885 ENOG4105N4N Protein of unknown function (DUF2766) BA058_01895 ENOG4105P23 (LipO)protein BA058_01900 ENOG41090A1 ferritin BA058_01905 ENOG4105VVZ metal-binding protein BA058_01910 ENOG4105E0U tyrosine-specific transport protein BA058_01915 ENOG4106RHG Yeca family BA058_01935 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BA058_01945 ENOG4105WH1 Two component transcriptional regulator luxr family BA058_01955 ENOG4105XVG cytoplasmic protein BA058_01960 ENOG4105VJY transcriptional regulator BA058_01965 ENOG4105CDA abc transporter atp-binding protein BA058_01970 ENOG4105E5Q amino acid AbC transporter BA058_01980 ENOG4105EAB amino acid AbC transporter BA058_01985 ENOG4108M9K flagella biosynthesis protein FliZ BA058_01990 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA058_01995 ENOG4105I03 Flagellin BA058_02000 ENOG4105DTS flagellar hook-associated BA058_02005 ENOG4105MQ3 flagellar protein FliS BA058_02010 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) BA058_02015 ENOG4105E5K Alpha-amylase BA058_02020 ENOG4108W9D (LipO)protein BA058_02025 ENOG41066VF YeeE YedE family protein BA058_02030 ENOG4105KSU Redox protein BA058_02035 ENOG4108RAV Conserved protein BA058_02045 ENOG4108UQN AraC family transcriptional regulator BA058_02050 ENOG4108V1U phospholipid-binding protein BA058_02055 ENOG410814C multidrug resistance protein BA058_02070 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BA058_02075 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA058_02080 ENOG41090PJ Flagellar assembly protein BA058_02085 ENOG4108JIR Flagellum-specific ATP synthase BA058_02090 ENOG4105GSA Flagellar export protein flij BA058_02095 ENOG4105WF4 Flagellar hook-length control protein BA058_02100 ENOG4107ZI8 flagellar basal body-associated protein flil BA058_02105 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA058_02110 ENOG4105DD5 Flagellar motor switch protein BA058_02115 ENOG4105K0P flagellar biosynthesis protein BA058_02120 ENOG4105CN7 Flagellar biosynthetic protein FliP BA058_02125 ENOG4105VS8 Flagellar biosynthetic protein fliq BA058_02130 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BA058_02135 ENOG4107TKS colanic acid capsular biosynthesis activation protein A BA058_02145 ENOG4105YX3 cellular response to acidity BA058_02150 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase BA058_02155 ENOG4105BZU Histidine kinase BA058_02160 ENOG4105VNZ cytoplasmic protein BA058_02165 ENOG4105CKW Inner membrane protein yedI BA058_02170 ENOG4105FDR Membrane BA058_02175 ENOG41090BB DNA mismatch endonuclease (vsr) BA058_02180 ENOG4105DVF Cytosine-specific methyltransferase BA058_02185 ENOG4105EST Metal Dependent Phosphohydrolase BA058_02190 ENOG4105Y0K Inner membrane protein YedR BA058_02200 ENOG4105ZIT Porin Gram-negative type BA058_02215 ENOG4107ZY3 Histidine kinase BA058_02220 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA058_02225 ENOG4105VT2 5-hydroxyisourate hydrolase BA058_02235 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) BA058_02240 ENOG4108MEK Metal-binding protein YodA BA058_02250 ENOG4105DFP Integrase BA058_02340 ENOG4108YX2 DNA-binding protein BA058_02375 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) BA058_02395 ENOG4105EYM Major Facilitator superfamily BA058_02400 ENOG4105BZ1 (ABC) transporter BA058_02415 ENOG4105C0W non-ribosomal peptide synthetase BA058_02435 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BA058_02440 ENOG4107ZSV Receptor BA058_02445 ENOG4105TNG K13735 adhesin invasin BA058_02450 ENOG4105TNG K13735 adhesin invasin BA058_02455 ENOG4105TNG K13735 adhesin invasin BA058_02460 ENOG4105TNG K13735 adhesin invasin BA058_02470 ENOG4105CSH Transporter BA058_02475 ENOG4105FYV Amp nucleosidase BA058_02480 ENOG4105CDY transcriptional regulatory protein BA058_02490 ENOG4106P55 Transcriptional regulator BA058_02495 ENOG4107R11 Transcriptional regulator BA058_02505 ENOG4105UQX Mate efflux family protein BA058_02555 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BA058_02585 ENOG4105C1G acyl-Coa dehydrogenase BA058_02590 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BA058_02595 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA058_02610 ENOG4105WH1 Two component transcriptional regulator luxr family BA058_02625 ENOG4105CMM transposase BA058_02635 ENOG4108PXI ErfK YbiS YcfS YnhG BA058_02650 ENOG4108YZT Adenosylcobinamide kinase BA058_02665 ENOG4105GTN ParB Domain Protein Nuclease BA058_02670 ENOG4105BZV Phosphoadenosine phosphosulfate reductase BA058_02675 ENOG4107W19 lmbE family BA058_02680 ENOG4108PBI Polysaccharide metabolism BA058_02685 ENOG4107RMY Bacterial transferase hexapeptide repeat protein BA058_02690 ENOG4105SRB Uncharacterized protein yaiO BA058_02700 ENOG4108RVA ribokinase BA058_02715 ENOG41080QX K07048 phosphotriesterase-related protein BA058_02720 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BA058_02770 ENOG410836F Transposase BA058_02815 ENOG4108HWH (ABC) transporter BA058_02820 ENOG4105EHG Permease protein BA058_02840 ENOG4108F5E vimentin BA058_02845 ENOG4108YIV BA058_02865 ENOG4106H6R UPF0380 protein BA058_02875 ENOG4106549 Antirestriction protein BA058_02880 ENOG4108YGG dna repair protein BA058_02885 ENOG4106WJE Protein of unknown function (DUF987) BA058_02890 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BA058_02920 ENOG4105DR8 Membrane BA058_02925 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) BA058_02930 ENOG4105DZ1 carboxypeptidase BA058_02935 ENOG4105CJB Exodeoxyribonuclease I BA058_02940 ENOG4105CUB amino acid BA058_02945 ENOG4105EQ1 Transcriptional regulator BA058_02950 ENOG4108535 NAD dependent epimerase/dehydratase family BA058_02955 ENOG4105KRQ Addiction module toxin, Txe YoeB family BA058_02960 ENOG4105VTW prevent-host-death family BA058_02970 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BA058_02975 ENOG4105CIH Imidazole acetol-phosphate transaminase BA058_02980 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BA058_02985 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BA058_02990 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BA058_02995 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BA058_03000 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BA058_03005 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) BA058_03010 ENOG4105C6Y Udp-glucose 6-dehydrogenase BA058_03015 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BA058_03020 ENOG4107QKV phosphomannomutase BA058_03025 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BA058_03035 ENOG4105CMR udp-glucose 4-epimerase BA058_03050 ENOG4105K64 Glycosyl transferase, family 2 BA058_03065 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA058_03070 ENOG4105G1A colanic acid biosynthesis protein BA058_03075 ENOG4107T8Q Glycosyl transferase (Group 1 BA058_03080 ENOG4105C74 pyruvyl transferase BA058_03085 ENOG4105PSV Polysaccharide Biosynthesis Protein BA058_03090 ENOG4105D3Q Sugar transferase BA058_03095 ENOG4107QKV phosphomannomutase BA058_03100 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BA058_03105 ENOG4106CD9 glycosyl transferase group 1 BA058_03110 ENOG4105FGF GDP-mannose mannosyl hydrolase BA058_03115 ENOG4105C30 Nad-dependent epimerase dehydratase BA058_03120 ENOG4105C0K Gdp-mannose 4,6-dehydratase BA058_03125 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF BA058_03130 ENOG4105ECJ Glycosyl Transferase BA058_03135 ENOG4108NYJ Colanic acid BA058_03140 ENOG4107RXY Glycosyl transferase BA058_03145 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB BA058_03150 ENOG41090RK glycosyl transferase BA058_03155 ENOG4105D75 Capsular exopolysaccharide family BA058_03160 ENOG4105KJF protein tyrosine phosphatase BA058_03165 ENOG4105DAY polysaccharide export protein BA058_03170 ENOG4105EE5 Membrane protein terC BA058_03175 ENOG4108GAE asmA family BA058_03185 ENOG4105DBI uridine monophosphokinase BA058_03190 ENOG4105BZU Histidine kinase BA058_03195 ENOG4105D03 DNA-3-methyladenine glycosylase II BA058_03200 ENOG4105R8A Heat shock protein BA058_03205 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding BA058_03210 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase BA058_03215 ENOG4108M24 von Willebrand factor, type A BA058_03220 ENOG4105ENT Efflux transporter rnd family, mfp subunit BA058_03225 ENOG4105BZS acriflavin resistance protein BA058_03230 ENOG4105BZS acriflavin resistance protein BA058_03235 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA058_03240 ENOG4105EB3 Histidine kinase BA058_03245 ENOG4105E3W Two component transcriptional regulator (Winged helix family BA058_03250 ENOG4105KWI UPF0339 protein BA058_03275 ENOG4105CFP Peptidase U32 BA058_03280 ENOG41076Z6 Uncharacterized protein yegR BA058_03285 ENOG4107TE5 Lipid kinase BA058_03295 ENOG4107WTH Galactitol-1-phosphate dehydrogenase BA058_03300 ENOG4105DT3 PTS system, galactitol-specific IIc component BA058_03305 ENOG41090UW PTS System BA058_03310 ENOG41082GB PTS system galactitol-specific transporter subunit IIA BA058_03315 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BA058_03320 ENOG4105D2N Aldolase BA058_03325 ENOG4105EIE fructose-bisphosphate aldolase BA058_03330 ENOG4105EAA nucleoside BA058_03335 ENOG4108KD5 ADP-ribosylation crystallin J1 BA058_03340 ENOG4108TFM Kinase, PfkB family BA058_03345 ENOG4105FDP GntR family transcriptional regulator BA058_03350 ENOG4108UQ1 hydrolase, family 25 BA058_03355 ENOG4105DWF phosphomethylpyrimidine kinase BA058_03360 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BA058_03375 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly BA058_03380 ENOG410662B Type-1 fimbrial protein BA058_03385 ENOG4105CW0 outer membrane usher protein BA058_03390 ENOG4108MQF Chaperone BA058_03395 ENOG41063W2 Fimbrial protein BA058_03405 ENOG41067AK Protein of unknown function (DUF2574) BA058_03410 ENOG4105D1F ATP-binding protein BA058_03415 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BA058_03420 ENOG4108KDT Molybdate metabolism regulator BA058_03425 ENOG4108KDT Molybdate metabolism regulator BA058_03440 ENOG4105KKX ATPase associated with various cellular activities aaa_5 BA058_03445 ENOG4105RD5 BA058_03450 ENOG4105DEG Vwa containing coxe family protein BA058_03455 ENOG410903U zinc ion binding BA058_03460 ENOG410903U zinc ion binding BA058_03465 ENOG4108YCW (LipO)protein BA058_03470 ENOG4108W15 Protein of unknown function (DUF1456) BA058_03475 ENOG4108NEV two component transcriptional regulator, LytTR family BA058_03480 ENOG4108HRK Histidine kinase BA058_03485 ENOG4108XDN Transcriptional regulator BA058_03495 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BA058_03500 ENOG4108IJ8 ABC transporter BA058_03505 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BA058_03510 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BA058_03515 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BA058_03520 ENOG4105CXG d-lactate dehydrogenase BA058_03525 ENOG41061WM D-Alanyl-D-Alanine BA058_03530 ENOG41069YE inner membrane protein yohC BA058_03535 ENOG4105KHU inner membrane protein YohD BA058_03540 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BA058_03545 ENOG4105ETP RND efflux system, outer membrane lipoprotein BA058_03555 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BA058_03565 ENOG41067MG lrgb family BA058_03575 ENOG4107GZ4 SanA protein BA058_03580 ENOG4105Y9N Membrane BA058_03585 ENOG4105BZ8 glutamate synthase BA058_03590 ENOG4107SJI Dehydrogenase BA058_03595 ENOG4108HWV )-transporter BA058_03600 ENOG4105C2J ABC transporter BA058_03605 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator BA058_03610 ENOG41060NJ transcriptional regulator BA058_03620 ENOG4105DHF Membrane BA058_03635 ENOG4105C4W S-formylglutathione hydrolase BA058_03640 ENOG4105D05 Receptor BA058_03650 ENOG4108IQI permease BA058_03655 ENOG4105DUM transcriptional regulator, lysR family BA058_03660 ENOG4105HMI Membrane BA058_03670 ENOG4105DD7 kinase (PfkB family BA058_03675 ENOG4105D9N nucleoside BA058_03685 ENOG4108Y4K DNA-binding transcriptional activator BA058_03690 ENOG4105D9N nucleoside BA058_03695 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) BA058_03700 ENOG4105DD7 kinase (PfkB family BA058_03705 ENOG4105DM4 PTS System BA058_03710 ENOG4105DE4 1-phosphofructokinase BA058_03715 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BA058_03720 ENOG4105S8Q sugar efflux transporter BA058_03725 ENOG4105KRS Proteinase inhibitor BA058_03735 ENOG4105DEI Mannitol dehydrogenase BA058_03740 ENOG4105CKI cobalamin synthesis protein BA058_03745 ENOG41076MN Phosphoesterase, PA-phosphatase related BA058_03750 ENOG4107TT5 NLP P60 protein BA058_03755 ENOG4105CXC rtn protein BA058_03760 ENOG4105E43 Extracellular solute-binding protein, family 5 BA058_03765 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BA058_03770 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BA058_03775 ENOG4108JQ5 ABC transporter BA058_03780 ENOG4105HG6 BA058_03785 ENOG4105C2C drug resistance transporter, Bcr CflA BA058_03790 ENOG4105I08 Pseudouridine synthase BA058_03795 ENOG4105CFI type iii restriction protein res subunit BA058_03815 ENOG4105E68 Sulfatase BA058_03825 ENOG4108MGN ATP-binding component of a transport system BA058_03830 ENOG4108MGN ATP-binding component of a transport system BA058_03840 ENOG4105WH1 Two component transcriptional regulator luxr family BA058_03845 ENOG4105KWW Biogenesis protein BA058_03850 ENOG4107QX9 Thiol disulfide interChange protein BA058_03855 ENOG4105DA4 cytochrome c-type biogenesis protein BA058_03865 ENOG4105X3C heme exporter protein BA058_03870 ENOG41060IM Heme exporter protein BA058_03875 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BA058_03880 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) BA058_03885 ENOG4105CUW cytochrome C-TYPE protein BA058_03890 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BA058_03895 ENOG4105GXZ Ferredoxin-type protein NapH BA058_03900 ENOG4108BGM Quinol dehydrogenase periplasmic component BA058_03905 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_03910 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BA058_03915 ENOG4108ZNS ferredoxin-type protein NapF BA058_03930 ENOG4105DWT malate dehydrogenase (quinone) BA058_03935 ENOG4105IBP Cyclic peptide transporter BA058_03940 ENOG4105CF1 Alkylated DNA repair protein BA058_03945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA058_03950 ENOG4105CJ2 (LipO)protein BA058_03955 ENOG4105FCK Membrane BA058_03965 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BA058_03970 ENOG41068CG regulatoR BA058_03975 ENOG4105BZU Histidine kinase BA058_03980 ENOG4105BZU Histidine kinase BA058_03985 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA058_03990 ENOG4107QP7 CoA-transferase subunit A BA058_03995 ENOG4107QNJ CoA-transferase subunit B BA058_04000 ENOG4105CRW Short chain fatty acid transporter BA058_04005 ENOG4105CHU acetyl-coa acetyltransferase BA058_04010 ENOG4105EDV vault protein BA058_04015 ENOG41081SK signal peptide protein BA058_04020 ENOG4107S52 alpha-2-macroglobulin domain protein BA058_04025 ENOG4108QJJ Protein of unknown function (DUF1175) BA058_04030 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) BA058_04035 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA058_04040 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BA058_04045 ENOG4107GHC outer membrane autotransporter BA058_04055 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BA058_04060 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BA058_04065 ENOG4105XPH Ferredoxin BA058_04070 ENOG4105FQR PH-inducible protein involved in stress response BA058_04075 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BA058_04080 ENOG4105CXY transporter BA058_04085 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BA058_04090 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B BA058_04095 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BA058_04105 ENOG4105DNE Transposase BA058_04115 ENOG4105CNV Aldolase BA058_04120 ENOG4105CSP Major Facilitator Superfamily BA058_04125 ENOG4105CXK mandelate racemase muconate lactonizing BA058_04130 ENOG4107258 Transcriptional regulator BA058_04140 ENOG4108UII YfaZ family BA058_04150 ENOG4108WMR Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core (By similarity) BA058_04165 ENOG4105C3I Nad-dependent epimerase dehydratase BA058_04175 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BA058_04190 ENOG4106GZG polymyxin resistance protein B BA058_04195 ENOG4105CEY Amp-dependent synthetase and ligase BA058_04200 ENOG4105DNI Converts SHCHC to OSB (By similarity) BA058_04205 ENOG4108IPT Naphthoate synthase BA058_04215 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BA058_04220 ENOG4105E4F Isochorismate synthase BA058_04225 ENOG4105TNS Conserved Protein BA058_04230 ENOG4107YB6 acetyltransferase, (GNAT) family BA058_04235 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BA058_04240 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is BA058_04245 ENOG4107VAM peptidase, m28 BA058_04250 ENOG4105GDX Domain of unknown function (DUF1877) BA058_04255 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA058_04260 ENOG4105C8S subunit m BA058_04265 ENOG4105D65 subunit l BA058_04270 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA058_04275 ENOG4107UFS subunit j BA058_04280 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA058_04290 ENOG4108IEH NADH dehydrogenase subunit g BA058_04295 ENOG4107QIZ NADH dehydrogenase BA058_04300 ENOG4105GKE subunit e BA058_04320 ENOG4107NQ8 LysR family Transcriptional regulator BA058_04325 ENOG4105CHM Aminotransferase BA058_04335 ENOG4107QWE )-transporter BA058_04340 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BA058_04360 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BA058_04365 ENOG4105C6K Malic enzyme BA058_04370 ENOG4105CSX c4-dicarboxylate anaerobic carrier BA058_04375 ENOG4105PTV Nudix Hydrolase BA058_04380 ENOG4108RE9 Phosphodiesterase BA058_04385 ENOG4108SHQ Glutathione S-transferase BA058_04390 ENOG4105CYM Glutathione S-transferase BA058_04395 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase BA058_04400 ENOG4105ECP epimerase BA058_04405 ENOG4105DNE Transposase BA058_04410 ENOG4108JEH abc transporter atp-binding protein BA058_04415 ENOG4106YG3 ABC transporter BA058_04420 ENOG4105DSP amino acid AbC transporter BA058_04425 ENOG4105E89 ABC transporter BA058_04430 ENOG4105E89 ABC transporter BA058_04435 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BA058_04440 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BA058_04445 ENOG4105E96 Colicin v production protein BA058_04450 ENOG4108S3P Sporulation domain protein BA058_04455 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BA058_04460 ENOG4108IDZ Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BA058_04465 ENOG4105DQR SNARE associated Golgi BA058_04475 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA058_04480 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) BA058_04485 ENOG4106WZ1 flagella biosynthesis regulator BA058_04490 ENOG4105F9N Major Facilitator Superfamily BA058_04495 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA058_04500 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) BA058_04505 ENOG4105MH2 YfcL protein BA058_04510 ENOG4108BPE -transporting atpase BA058_04515 ENOG4105EJ9 Membrane BA058_04520 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) BA058_04525 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BA058_04535 ENOG4108DG9 Smr protein MutS2 BA058_04550 ENOG4105US4 fimbrial-like protein yfcP BA058_04555 ENOG4105UGQ Fimbrial BA058_04560 ENOG4105NEV Fimbrial BA058_04565 ENOG4108FZ9 Chaperone BA058_04570 ENOG4106PG1 outer membrane usher protein BA058_04580 ENOG4108BY2 phosphohistidine phosphatase BA058_04585 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA058_04595 ENOG4105KZW UPF0381 protein BA058_04600 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BA058_04605 ENOG410903C (LipO)protein BA058_04610 ENOG4105S64 Formate nitrite transporter BA058_04625 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BA058_04630 ENOG4105D7K pfkb domain protein BA058_04635 ENOG4108HKT sucrose-6-phosphate hydrolase BA058_04640 ENOG4106NDP Transcriptional regulator BA058_04650 ENOG4105BZC d-serine deaminase BA058_04655 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA058_04660 ENOG4105CW7 secretion protein, HlyD family BA058_04665 ENOG4108WQH regulatoR BA058_04670 ENOG4105BZU Histidine kinase BA058_04675 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BA058_04680 ENOG4108N2Y auxin Efflux BA058_04685 ENOG4105CFN oxalyl-CoA decarboxylase BA058_04730 ENOG4105I1F Resistance protein BA058_04765 ENOG4105D13 transposase BA058_04805 ENOG4108X73 DNA- binding protein BA058_04810 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BA058_04815 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BA058_04820 ENOG4105KK6 nuclease BA058_04845 ENOG4108EHY type IV secretion system BA058_04855 ENOG4105CMA conjugation trbi family protein BA058_04885 ENOG4105CFN oxalyl-CoA decarboxylase BA058_04895 ENOG4108V08 YfdX protein BA058_04910 ENOG4105W9M Membrane BA058_04915 ENOG4105D1S lipid A biosynthesis BA058_04920 ENOG4105CHM Aminotransferase BA058_04925 ENOG4108HRK Histidine kinase BA058_04930 ENOG4105DY9 regulatoR BA058_04935 ENOG4108CIP transcriptional regulator BA058_04940 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA058_04945 ENOG4105CN9 Peptidase m42 family protein BA058_04950 ENOG4105DC7 peptidase M24 BA058_04955 ENOG410863U PTS System BA058_04960 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) BA058_04970 ENOG4105VCT ion-transport protein YfeO BA058_04975 ENOG4109076 Conserved Protein BA058_04990 ENOG4105D9N nucleoside BA058_04995 ENOG4108KMM Diguanylate cyclase BA058_05010 ENOG4105HZG regulatoR BA058_05015 ENOG4105GXM Putative transcription regulator (DUF1323) BA058_05020 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BA058_05045 ENOG4105CN8 Transcriptional regulator BA058_05055 ENOG4105EAA nucleoside BA058_05060 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BA058_05065 ENOG4108NFH Sugar hydrolase BA058_05070 ENOG4108M0I Transcriptional regulator BA058_05075 ENOG4105DHU Bile acid BA058_05080 ENOG4105VRT cytoplasmic protein BA058_05085 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BA058_05100 ENOG4105C6T cysteine synthase BA058_05105 ENOG4105KZ7 phosphocarrier protein hpr BA058_05110 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA058_05115 ENOG4105C5Y PTS System BA058_05125 ENOG4105M0Y BA058_05130 ENOG4105C6T cysteine synthase BA058_05135 ENOG4108IJ6 ABC transporter BA058_05140 ENOG4105ECW sulfate abc transporter BA058_05145 ENOG4108I5D sulfate abc transporter BA058_05150 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BA058_05155 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BA058_05160 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BA058_05165 ENOG4105C5Y PTS System BA058_05170 ENOG4105EZR dyp-type peroxidase family protein BA058_05175 ENOG4105E7K (LipO)protein BA058_05180 ENOG4105QZU Inner membrane protein YfeZ BA058_05185 ENOG4108R6G acetyltransferase BA058_05190 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase BA058_05200 ENOG4108K3Z AraC family transcriptional regulator BA058_05205 ENOG4108X49 Ethanolamine utilization protein EutK BA058_05210 ENOG4106D67 ethanolamine utilization protein BA058_05220 ENOG4105CPD ethanolamine ammonia-lyase BA058_05225 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase BA058_05230 ENOG4105ENY Ethanolamine utilization protein eutH BA058_05235 ENOG4105C0A alcohol dehydrogenase BA058_05240 ENOG4107RWI ethanolamine utilization protein eutJ BA058_05245 ENOG4108EKI Dehydrogenase BA058_05250 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml BA058_05255 ENOG4105KNY Microcompartments protein BA058_05260 ENOG4107WUY phosphate acetyltransferase BA058_05265 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase BA058_05270 ENOG4105NDK ethanolamine utilization protein BA058_05275 ENOG4106S4J ethanolamine utilization protein EutP BA058_05280 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place BA058_05285 ENOG4105C6K Malic enzyme BA058_05290 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA058_05295 ENOG4105CV1 Transketolase (EC 2.2.1.1) BA058_05300 ENOG4108PVD exported protein BA058_05310 ENOG4105BZ8 glutamate synthase BA058_05315 ENOG4105BZU Histidine kinase BA058_05320 ENOG4105BZS acriflavin resistance protein BA058_05330 ENOG4105KUZ arsenate reductase BA058_05335 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) BA058_05345 ENOG4106KED esterase YpfH BA058_05355 ENOG4105CGZ zinc metallopeptidase BA058_05370 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BA058_05380 ENOG4105RH4 Glycine cleavage system transcriptional repressor BA058_05385 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA058_05390 ENOG4105C02 permease BA058_05395 ENOG4105ERG peptidase m48, ste24p BA058_05400 ENOG4105K89 arsenate reductase BA058_05410 ENOG4105C2W permease BA058_05420 ENOG4105CXB phosphoribosylaminoimidazole synthetase BA058_05425 ENOG4108V3E phosphoribosylglycinamide formyltransferase BA058_05430 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BA058_05435 ENOG4105C9X ppx gppa phosphatase BA058_05450 ENOG41062G3 Protein of unknown function (DUF2633) BA058_05455 ENOG4108ZMA Outer membrane lipoprotein BA058_05460 ENOG41066DY Membrane BA058_05470 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BA058_05475 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BA058_05495 ENOG4105VPD cellular component movement BA058_05510 ENOG4105N21 Membrane BA058_05540 ENOG4108JQB penicillin-binding protein 1C BA058_05545 ENOG4105DN3 alpha-2-macroglobulin domain protein BA058_05550 ENOG4105KHC sulfurtransferase BA058_05555 ENOG4105YYA enhanced serine sensitivity protein SseB BA058_05565 ENOG4105WVQ Fe-S assembly protein IscX BA058_05570 ENOG4108ZIT Ferredoxin, 2FE-2S BA058_05590 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BA058_05605 ENOG4105CVS RNA methyltransferase TrmH family, group 1 BA058_05615 ENOG4107XM9 (LipO)protein BA058_05620 ENOG4108MN2 Stationary phase inducible protein CsiE BA058_05625 ENOG4105D8G Major Facilitator superfamily BA058_05630 ENOG4108SB3 DoxX Family BA058_05640 ENOG4105Y25 Transposase BA058_05645 ENOG4105DQ6 Transposase BA058_05650 ENOG4108ZKT aldose 1-epimerase BA058_05655 ENOG4105CPQ Dehydrogenase BA058_05660 ENOG4105CNN ABC, transporter BA058_05665 ENOG4108F37 ATP-binding component of a transport system BA058_05670 ENOG4105FCA ABC transporter periplasmic-binding protein YphF BA058_05675 ENOG4107HQ7 repeat protein BA058_05680 ENOG4108NZE NAGC-like transcriptional regulator BA058_05690 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BA058_05695 ENOG4108YZA Nitrogen regulatory protein pii BA058_05700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA058_05705 ENOG4108SKK alpha helix protein BA058_05710 ENOG4107WP9 Histidine kinase BA058_05715 ENOG4108ETH Formylglycinamide ribotide synthetase BA058_05725 ENOG4108Z6B deaminase BA058_05730 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BA058_05735 ENOG4106G6Q Transcriptional regulator BA058_05740 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BA058_05760 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BA058_05780 ENOG4105C3F Signal peptidase i BA058_05790 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BA058_05795 ENOG4105VQK sigma E regulatory protein, MucB RseB BA058_05800 ENOG41069PW sigma-e factor negative regulatory protein BA058_05805 ENOG4105EMN RNA polymerase sigma factor BA058_05815 ENOG4108IYU L-aspartate oxidase BA058_05825 ENOG4105C1J atp-dependent rna helicase BA058_05830 ENOG41090KR LysR family transcriptional Regulator BA058_05850 ENOG4105EIB trna rrna methyltransferase BA058_05860 ENOG4105K63 Thioredoxin BA058_05865 ENOG4106IUH DTW domain containing protein BA058_05870 ENOG4105CD5 CoA-binding domain protein BA058_05875 ENOG4105JIM Phosphatidylserine synthase BA058_05880 ENOG4105T42 (LipO)protein BA058_05885 ENOG4105CSH Transporter BA058_05905 ENOG4105DQ6 Transposase BA058_05910 ENOG4105Y25 Transposase BA058_05940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BA058_05945 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BA058_05950 ENOG4105C34 Pseudouridine synthase BA058_05955 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BA058_05965 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BA058_05970 ENOG4105CQC Prephenate dehydratase BA058_05975 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BA058_05980 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BA058_05985 ENOG4105QP9 Protein of unknown function (DUF2799) BA058_05990 ENOG4108WS1 BA058_05995 ENOG4108KHX Diguanylate cyclase BA058_06000 ENOG41090EK ompa motb domain protein BA058_06025 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BA058_06030 ENOG4106KVJ cytochrome C assembly protein BA058_06035 ENOG4108JU6 CBS domain protein BA058_06050 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BA058_06055 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BA058_06060 ENOG4105VDB UPF0125 protein BA058_06065 ENOG4108Z1B Cyclase dehydrase BA058_06080 ENOG4105DFP Integrase BA058_06145 ENOG4108YX2 DNA-binding protein BA058_06230 ENOG4105D5U fad dependent oxidoreductase BA058_06235 ENOG4105C26 Dehydrogenase BA058_06240 ENOG4108JPW Aminotransferase BA058_06245 ENOG4105C85 amino acid BA058_06250 ENOG4108PVQ transcriptional regulator BA058_06255 ENOG4109066 lysm domain bon superfamily protein BA058_06260 ENOG4105VPI YqaE family transport protein BA058_06265 ENOG41080HT Transcriptional regulator, arsr family BA058_06270 ENOG4108V62 Rhodanese domain protein BA058_06275 ENOG4108X73 DNA- binding protein BA058_06280 ENOG4108RNS Exports L-alanine (By similarity) BA058_06285 ENOG4108WMJ Protein of unknown function (DUF2002) BA058_06290 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) BA058_06300 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BA058_06305 ENOG4105WAZ (Glutaredoxin-like protein) NrdH BA058_06310 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BA058_06315 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BA058_06320 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BA058_06325 ENOG4108IJ7 Glycine betaine BA058_06330 ENOG4108HQS Glycine betaine BA058_06335 ENOG4105GIJ Glycine betaine BA058_06340 ENOG4105EQ0 Major Facilitator superfamily BA058_06345 ENOG4108UMN azlc family BA058_06350 ENOG4105ZED uncharacterized protein ygaH BA058_06355 ENOG4105NTK Transcriptional repressor Mpra BA058_06360 ENOG4105CW7 secretion protein, HlyD family BA058_06365 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA058_06380 ENOG4105W39 Membrane BA058_06385 ENOG4107VXZ Hydrolase BA058_06415 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BA058_06420 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA058_06440 ENOG4107TH8 cina domain protein BA058_06445 ENOG4105CVE Lytic murein transglycosylase BA058_06450 ENOG410787A Pts system, glucitol sorbitol-specific BA058_06455 ENOG4105DZY Pts system, glucitol sorbitol-specific BA058_06460 ENOG4105VI0 Pts system, glucitol sorbitol-specific BA058_06465 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase BA058_06470 ENOG4105J92 DNA-binding transcriptional activator GutM BA058_06475 ENOG410804X Transcriptional regulator BA058_06480 ENOG4105C2X Arabinose 5-phosphate isomerase BA058_06485 ENOG4108JUA Transcriptional regulator BA058_06495 ENOG4107QZF nitrite reductase NADPH large subunit BA058_06500 ENOG4105C8H hydrogenase maturation protein Hypf BA058_06505 ENOG4108RC0 Electron transport protein BA058_06510 ENOG4105DDV Transcriptional regulator (LacI family BA058_06515 ENOG4105C5Y PTS System BA058_06520 ENOG4105CS2 ec 3.2.1.21 BA058_06525 ENOG4108Z3N Transcriptional regulator BA058_06530 ENOG4108MG9 hydrogenase 3 maturation protease BA058_06535 ENOG4105I6X formate hydrogenlyase maturation BA058_06540 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit BA058_06545 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit BA058_06550 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA058_06555 ENOG4107TDF Formate hydrogenlyase subunit 4 BA058_06560 ENOG4107R30 NADH dehydrogenase BA058_06565 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) BA058_06575 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA BA058_06580 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) BA058_06585 ENOG4107RSS Hydrogenase accessory protein HypB BA058_06590 ENOG41083WG hydrogenase assembly chaperone BA058_06595 ENOG4105CQS hydrogenase expression formation protein HypD BA058_06600 ENOG4105C45 hydrogenase expression formation protein (HypE) BA058_06605 ENOG4108JUA Transcriptional regulator BA058_06615 ENOG4105VXR cytoplasmic protein BA058_06665 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BA058_06675 ENOG4105MVE transcriptional regulator BA058_06685 ENOG4105G63 Type III effector Hrp-dependent BA058_06690 ENOG4105FB2 class II Aldolase BA058_06695 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BA058_06700 ENOG4105C6Z Gluconate BA058_06715 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA058_06720 ENOG4108K5P (LipO)protein BA058_06735 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) BA058_06740 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BA058_06755 ENOG4105N0Z inner membrane protein ygbE BA058_06770 ENOG4105C11 sulfate adenylyltransferase), subunit 2 BA058_06775 ENOG4108MXK alkaline phosphatase isozyme conversion BA058_06780 ENOG4107635 Hok Gef family protein BA058_06800 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BA058_06805 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BA058_06810 ENOG4105WQV ferredoxin-like protein BA058_06815 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BA058_06820 ENOG4105YBM electron transfer flavoprotein subunit ygcQ BA058_06825 ENOG4106IKH Electron transfer flavoprotein BA058_06830 ENOG4105C54 Major Facilitator superfamily BA058_06835 ENOG4107R3A FAD linked oxidase domain protein BA058_06840 ENOG4105CHR reductase BA058_06845 ENOG4108ITV Inner membrane protein yqcE BA058_06850 ENOG4108CWB sugar kinase ygcE BA058_06875 ENOG4105WBN Transcriptional regulator (LacI family BA058_06880 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BA058_06890 ENOG4105HA9 of methanol dehydrogenase type BA058_06900 ENOG4105HA9 of methanol dehydrogenase type BA058_06915 ENOG4105DXN mazG family BA058_06920 ENOG4105MZG transcriptional modulator of maze toxin, mazf BA058_06925 ENOG4106A2Z transcriptional regulator antitoxin, MazE BA058_06930 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BA058_06935 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BA058_06940 ENOG4105BZU Histidine kinase BA058_06945 ENOG4105EQX glucarate dehydratase BA058_06950 ENOG4105EQX glucarate dehydratase BA058_06955 ENOG4105DJB Major Facilitator Superfamily BA058_06960 ENOG4105QDK Flavodoxin BA058_06965 ENOG4105DR9 pseudouridine synthase BA058_06970 ENOG4105WP7 tRNA pseudouridine synthase C BA058_06990 ENOG4105EWT decarboxylase family BA058_06995 ENOG4105C44 Serine transporter BA058_07000 ENOG4105EJQ L-serine dehydratase BA058_07005 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease BA058_07010 ENOG4105C0A alcohol dehydrogenase BA058_07015 ENOG4107W7X Aldolase BA058_07020 ENOG4105EDR glucose galactose transporter BA058_07025 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) BA058_07030 ENOG4105CMG Carbohydrate kinase BA058_07040 ENOG4107EDW L-fucose operon activator BA058_07045 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) BA058_07050 ENOG4105M08 Membrane BA058_07055 ENOG4105ETT transcriptional Regulator, LysR family BA058_07060 ENOG4105M5B (LipO)protein BA058_07065 ENOG4105C9B Cysteine desulfurase BA058_07070 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BA058_07075 ENOG4105CUZ uba thif-type nad fad binding protein BA058_07080 ENOG4105CA3 membrane-bound lytic murein transglycosylase BA058_07120 ENOG4108ZG0 Ompa motb domain protein BA058_07130 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BA058_07215 ENOG4105C2X Arabinose 5-phosphate isomerase BA058_07220 ENOG4105C87 Aminotransferase class I and II BA058_07225 ENOG4105CI1 PTS System BA058_07230 ENOG4105CID antiterminator BA058_07235 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BA058_07240 ENOG4107QZM n-acetylglutamate synthase BA058_07245 ENOG4107QYX exodeoxyribonuclease v alpha BA058_07250 ENOG4107QKA exodeoxyribonuclease V beta BA058_07255 ENOG4107QXK peptidase BA058_07260 ENOG4105DSY exodeoxyribonuclease V, gamma BA058_07265 ENOG4105RVB Prepilin peptidase dependent protein c BA058_07270 ENOG4105SEN Protein of unknown function (DUF2509) BA058_07275 ENOG4105JCS prepilin peptidase dependent protein BA058_07280 ENOG4105IPU prepilin peptidase dependent protein A BA058_07295 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BA058_07320 ENOG4105EE5 Membrane protein terC BA058_07325 ENOG4105SUV lipoprotein YgdR BA058_07330 ENOG4105CPC Aldo Keto reductase BA058_07335 ENOG4107S74 Lysophospholipid transporter LplT BA058_07340 ENOG4105CEY Amp-dependent synthetase and ligase BA058_07345 ENOG41060NJ transcriptional regulator BA058_07350 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BA058_07355 ENOG4105RQF LysR family Transcriptional regulator BA058_07365 ENOG4107QNK )-transporter BA058_07370 ENOG4105CHR reductase BA058_07380 ENOG4105CHU acetyl-coa acetyltransferase BA058_07385 ENOG4108MHD transport protein BA058_07395 ENOG4108K5P (LipO)protein BA058_07400 ENOG4105C7W Xanthine dehydrogenase BA058_07405 ENOG4108HR6 Dehydrogenase BA058_07410 ENOG4108UTP (2Fe-2S)-binding domain protein BA058_07415 ENOG4108JUB Transcriptional regulator BA058_07420 ENOG4105IW6 Carbamoyltransferase BA058_07425 ENOG4107RCH Diaminopropionate ammonia-lyase BA058_07430 ENOG4107S4Y M20 DapE family protein YgeY BA058_07435 ENOG4105CD3 dihydroorotase BA058_07440 ENOG4105C5B carbamate kinase BA058_07445 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family BA058_07450 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC BA058_07455 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase BA058_07460 ENOG4105BZ8 glutamate synthase BA058_07465 ENOG4107UUR Chlorohydrolase aminohydrolase BA058_07470 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase BA058_07475 ENOG4105C7W Xanthine dehydrogenase BA058_07480 ENOG4105C2W permease BA058_07485 ENOG4107QUY Guanine deaminase BA058_07490 ENOG4105C7N Xanthine uracil vitamin C permease BA058_07495 ENOG4108R8B oxidoreductase Fe-S subunit BA058_07500 ENOG4105BZ8 glutamate synthase BA058_07510 ENOG4105C2W permease BA058_07520 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BA058_07525 ENOG4105CRK lysyL-tRNA synthetase BA058_07535 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BA058_07540 ENOG4105T95 Thiol disulfide interChange protein BA058_07545 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA058_07550 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BA058_07555 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB BA058_07560 ENOG4105Y75 tpr repeat protein BA058_07565 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) BA058_07570 ENOG4108UT2 hemolysin iii BA058_07580 ENOG4105CS2 ec 3.2.1.21 BA058_07585 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BA058_07590 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BA058_07600 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BA058_07605 ENOG4105D0A hydroxylase BA058_07610 ENOG4107RAQ aminopeptidase BA058_07630 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BA058_07640 ENOG4108JQ1 Dehydrogenase BA058_07665 ENOG4105DEQ transcriptional regulator BA058_07670 ENOG4105MPN Membrane BA058_07675 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BA058_07680 ENOG4105D64 Mechanosensitive ion channel BA058_07685 ENOG4105D2N Aldolase BA058_07725 ENOG4107Z1W Fructose transport system kinase BA058_07730 ENOG4108R4K DNA-binding, transcriptional regulator BA058_07735 ENOG4108Q8A Fructose-1,6-bisphosphatase BA058_07740 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein BA058_07745 ENOG4105CTS PTS system mannitol-specific BA058_07750 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia BA058_07755 ENOG4105EPW hflc protein BA058_07760 ENOG4105CV1 Transketolase (EC 2.2.1.1) BA058_07765 ENOG4108K0D peptidase, M48 BA058_07780 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BA058_07805 ENOG4107QNK )-transporter BA058_07815 ENOG4105RWS endonuclease I BA058_07820 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BA058_07825 ENOG4105D7Z glutathione synthase BA058_07840 ENOG4105CZX twitching motility protein BA058_07845 ENOG4105DFA alanine racemase domain protein BA058_07850 ENOG4108VIA integral membrane protein BA058_07860 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BA058_07865 ENOG4105CSA Coproporphyrinogen iii oxidase BA058_07870 ENOG4106MH3 alpha helix chain BA058_07875 ENOG4105HDK L-asparaginase BA058_07880 ENOG4105K33 Periplasmic Protein BA058_07890 ENOG41090ED Protein with unknown function (DUF469) BA058_07895 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BA058_07900 ENOG4105CEN a g-specific adenine glycosylase BA058_07915 ENOG4105EAA nucleoside BA058_07920 ENOG4105CXN decarboxylase BA058_07925 ENOG4108UQV Membrane BA058_07945 ENOG4108I6E Sulfatase BA058_07950 ENOG4105E5H Transposase BA058_07955 ENOG4108YXQ IS66 Orf2 family protein BA058_07970 ENOG4105T40 surface antigen msp4 family protein BA058_07995 ENOG4105D70 Integrase catalytic subunit BA058_08000 ENOG41067TZ transcriptional regulator, MarR family BA058_08020 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR BA058_08030 ENOG4106P2F Pfam:Pili_assembly_C BA058_08035 ENOG4106PG1 outer membrane usher protein BA058_08040 ENOG4108ZJG MrfB protein BA058_08045 ENOG4105HMV Fimbrial protein BA058_08075 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta BA058_08085 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BA058_08090 ENOG4105CXY transporter BA058_08100 ENOG4108ZQS transposase BA058_08175 ENOG4105D5K Hemolysin activator protein BA058_08195 ENOG4105E9Q Acyl-transferase BA058_08220 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) BA058_08225 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BA058_08250 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA058_08260 ENOG4105C2D reductase BA058_08265 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA058_08275 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia BA058_08285 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BA058_08300 ENOG4105EDR glucose galactose transporter BA058_08305 ENOG4108RVA ribokinase BA058_08310 ENOG4107FB0 transcriptional regulator DeoR family BA058_08315 ENOG4105M71 acetolactate synthase 1 regulatory subunit BA058_08320 ENOG4105M71 acetolactate synthase 1 regulatory subunit BA058_08355 ENOG4105KF5 hemolysin expression-modulating protein BA058_08370 ENOG4108P8R BA058_08380 ENOG4105F4K antigen 43 BA058_08385 ENOG4108PZQ Inner membrane protein YeeR BA058_08400 ENOG4106H6R UPF0380 protein BA058_08405 ENOG4105MFG Antirestriction protein BA058_08410 ENOG4108YGG dna repair protein BA058_08415 ENOG4106WJE Protein of unknown function (DUF987) BA058_08425 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BA058_08455 ENOG4105C2X Arabinose 5-phosphate isomerase BA058_08460 ENOG4105ECX polysaccharide export BA058_08465 ENOG4107V1M polysaccharide export protein BA058_08470 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) BA058_08475 ENOG4105E12 capsule polysaccharide BA058_08480 ENOG41084CK capsule polysaccharide BA058_08495 ENOG4108UW5 maltose o-acetyltransferase BA058_08500 ENOG4105D5D udp-galactopyranose mutase BA058_08505 ENOG4105K64 Glycosyl transferase, family 2 BA058_08525 ENOG41090SZ ABC-2 type transporter BA058_08530 ENOG4105U1E general secretion pathway protein M BA058_08550 ENOG4105X5Z General secretion pathway protein I BA058_08560 ENOG4108VAU general secretion pathway protein G BA058_08565 ENOG4105D7Q type ii secretion system BA058_08570 ENOG4107QHF type ii secretion system protein e BA058_08585 ENOG410765S (LipO)protein BA058_08590 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) BA058_08595 ENOG4105F88 accessory colonization factor AcfD BA058_08605 ENOG4105DAA L-lactate BA058_08610 ENOG4107QP3 malate synthase g BA058_08615 ENOG4108ZJF Glcg protein BA058_08620 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BA058_08625 ENOG4105EU8 FAD linked oxidase domain protein BA058_08630 ENOG4105CQB FAD linked oxidase domain protein BA058_08635 ENOG4108KWP DNA-binding transcriptional regulator GlcC BA058_08655 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BA058_08660 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BA058_08670 ENOG4108M8S permease YjgP YjgQ family protein BA058_08675 ENOG4108UUE Transcriptional regulator BA058_08685 ENOG4108S55 polysaccharide biosynthesis protein BA058_08690 ENOG4106FPV ATP-binding protein YghR BA058_08695 ENOG4108NDC ATP-binding protein yghS BA058_08700 ENOG4108GH0 ATP-binding protein yghT BA058_08705 ENOG4105CJ3 phosphate transporter BA058_08710 ENOG4106032 Glutathionylspermidine synthase BA058_08715 ENOG4105CYM Glutathione S-transferase BA058_08720 ENOG41082MF Hydrogenase assembly chaperone hypC hupF BA058_08725 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) BA058_08730 ENOG4108WGS hydrogenase 2-specific chaperone BA058_08735 ENOG4108USZ hydrogenase BA058_08740 ENOG4105DPX Hydrogenase, large subunit BA058_08745 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit BA058_08750 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BA058_08755 ENOG4105E3S small subunit BA058_08765 ENOG410900S Protein of unknown function (DUF2623) BA058_08775 ENOG4105CPC Aldo Keto reductase BA058_08785 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BA058_08790 ENOG4108ZZF transport protein (ExbD) BA058_08795 ENOG4105CWK Biopolymer transport protein, ExbB BA058_08805 ENOG4105C28 cystathionine BA058_08810 ENOG4108K81 inner membrane protein YghB BA058_08815 ENOG4105CF7 AraC family transcriptional regulator BA058_08825 ENOG4108I6A alcohol dehydrogenase BA058_08830 ENOG4105CV8 reductase BA058_08835 ENOG4105ZKC Conserved Protein BA058_08845 ENOG4105CCT upf0313 protein BA058_08850 ENOG4107YCY Transcriptional regulator BA058_08860 ENOG4105CPQ Dehydrogenase BA058_08865 ENOG4105DG4 malate L-lactate dehydrogenase BA058_08870 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BA058_08880 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BA058_08885 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BA058_08890 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BA058_08895 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA058_08900 ENOG4108J59 Extracellular solute-binding protein, family 5 BA058_08905 ENOG4105F4I Transcriptional regulator BA058_08910 ENOG4105H4F exported protein BA058_08915 ENOG4105XJC Two component transcriptional regulator (Winged helix family BA058_08920 ENOG4105DHQ Histidine kinase BA058_08925 ENOG4107DEU Inner membrane protein YgiZ BA058_08940 ENOG4105NF4 modulator of drug activity BA058_08945 ENOG4105VRH Antibiotic biosynthesis monooxygenase BA058_08950 ENOG4106KNT transcriptional regulator BA058_08960 ENOG4105EHG Permease protein BA058_08965 ENOG4105DQ5 transport system permease protein BA058_08970 ENOG4105E0A ABC, transporter BA058_08980 ENOG4105CT4 transporter BA058_09000 ENOG4108RVA ribokinase BA058_09020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA058_09025 ENOG4105IPS esterase BA058_09030 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BA058_09040 ENOG41087AY ADP-Ribose pyrophosphatase BA058_09045 ENOG4105DFG type I secretion outer membrane protein BA058_09060 ENOG4106032 Glutathionylspermidine synthase BA058_09065 ENOG4108MR7 Arylsulfotransferase BA058_09070 ENOG4108N92 Thiol disulfide Interchange Protein BA058_09080 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BA058_09100 ENOG4105W0Z cytoplasmic protein BA058_09110 ENOG4105PV3 Inner membrane protein yqiJ BA058_09115 ENOG4107S78 Band 7 protein BA058_09130 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) BA058_09135 ENOG4105I7R Adenylate cyclase BA058_09145 ENOG4106MWK domain protein BA058_09160 ENOG4107ZVW dihydroneopterin aldolase BA058_09170 ENOG4105EJC lysr family transcriptional regulator BA058_09175 ENOG4106DSS Tartrate dehydratase subunit alpha BA058_09180 ENOG4107GFK fumarate BA058_09185 ENOG4107QPK )-transporter BA058_09195 ENOG4105VCC 30S ribosomal protein S21 BA058_09200 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BA058_09205 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA058_09220 ENOG4105Q26 Siderophore-interacting protein BA058_09225 ENOG4105NTW Transcriptional regulator BA058_09230 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BA058_09240 ENOG4108Y51 tRNA-binding protein BA058_09245 ENOG4105CQ4 Transcriptional regulator BA058_09250 ENOG4105CNT hydrolase family 2 BA058_09255 ENOG4105FK9 beta-D-galactosidase beta subunit BA058_09260 ENOG4105E5D amino acid BA058_09270 ENOG4107WCA isomerase BA058_09275 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BA058_09280 ENOG4108Z3N Transcriptional regulator BA058_09285 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase BA058_09295 ENOG4108VKG metal-dependent hydrolase BA058_09300 ENOG4108UB4 uncharacterized protein ygjQ BA058_09305 ENOG4105EE0 oxidoreductase BA058_09310 ENOG4105DU1 integral membrane protein, terc BA058_09320 ENOG4105P66 Membrane BA058_09325 ENOG4105CTX dehydratase BA058_09335 ENOG4105DPW Major facilitator superfamily MFS_1 BA058_09360 ENOG4107YCY Transcriptional regulator BA058_09365 ENOG4106W5V Membrane BA058_09370 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) BA058_09375 ENOG4105WAY exported protein BA058_09380 ENOG4105NE1 Conserved Protein BA058_09385 ENOG41090KG Inner membrane protein YqjE BA058_09390 ENOG4105YJD BA058_09395 ENOG4108VBZ doxx family BA058_09400 ENOG4105CHF Glutathione S-transferase BA058_09405 ENOG4105KAF membrAne BA058_09410 ENOG4105CWB LysR family transcriptional Regulator BA058_09415 ENOG4108CNN domain protein BA058_09420 ENOG4106D80 Uncharacterized protein YhaL BA058_09430 ENOG4105C44 Serine transporter BA058_09435 ENOG4105EJQ L-serine dehydratase BA058_09440 ENOG4105KME endoribonuclease L-psp BA058_09445 ENOG4105C6N Formate acetyltransferase BA058_09460 ENOG4105C7B Threonine dehydratase BA058_09465 ENOG410811B TRANSCRIPTIONal BA058_09480 ENOG4105BZW Glycerate kinase BA058_09485 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA058_09495 ENOG4105DJB Major Facilitator Superfamily BA058_09500 ENOG4105CTX dehydratase BA058_09505 ENOG4105ZEG Suppressor protein BA058_09510 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression BA058_09515 ENOG4105E98 transcriptional regulator DeoR family BA058_09520 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BA058_09525 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BA058_09535 ENOG4105F3R pts system mannose fructose sorbose family iid BA058_09540 ENOG4108YTN IIa component BA058_09545 ENOG4105CE4 GlcNAc 6-P deacetylase BA058_09550 ENOG4105E70 isomerase BA058_09560 ENOG4108UZY PTS System BA058_09565 ENOG4105ETZ PTS System BA058_09570 ENOG4105F3R pts system mannose fructose sorbose family iid BA058_09575 ENOG4106HBN Galactosamine-6-phosphate isomerase BA058_09580 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BA058_09585 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) BA058_09600 ENOG4105W4M Transport-associated protein BA058_09605 ENOG4107S21 permease BA058_09610 ENOG4105K4T epimerase BA058_09615 ENOG4107R7Y intracellular protease Pfpi family BA058_09630 ENOG4108YYD acetyltransferase BA058_09635 ENOG4105XPQ lipid carrier protein BA058_09640 ENOG4105CFP Peptidase U32 BA058_09645 ENOG4106RZ4 Peptidase U32 BA058_09650 ENOG4105DEN Luciferase family BA058_09655 ENOG4105CIC tryptophan-specific transport protein BA058_09665 ENOG4105C1J atp-dependent rna helicase BA058_09670 ENOG4105RT1 May be involved in cell division (By similarity) BA058_09685 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BA058_09700 ENOG4105CHV Transcription elongation factor NusA BA058_09745 ENOG4105EEI dihydropteroate synthase BA058_09750 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BA058_09755 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) BA058_09760 ENOG4105HBR Rna-binding protein BA058_09765 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BA058_09770 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BA058_09780 ENOG4105QYV Membrane BA058_09795 ENOG4105EAH synthase BA058_09800 ENOG4105HVQ Regulatory factor of maltose metabolism BA058_09810 ENOG4105VFK BolA family BA058_09815 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BA058_09820 ENOG4105E3I toluene tolerance BA058_09825 ENOG4107PE3 Mammalian cell entry related domain protein BA058_09830 ENOG4105CY3 ABC transporter, permease BA058_09835 ENOG4105DHJ ABC, transporter BA058_09840 ENOG4105FEU K -dependent Na -Ca exchanger BA058_09845 ENOG4105C2X Arabinose 5-phosphate isomerase BA058_09855 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BA058_09860 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BA058_09865 ENOG4108IUZ ABC transporter BA058_09870 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA058_09875 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BA058_09880 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BA058_09890 ENOG41080Z8 PHOSPHOCARRIER protein BA058_09895 ENOG4108NIH transferase activity, transferring phosphorus-containing groups BA058_09905 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BA058_09910 ENOG4105BZU Histidine kinase BA058_09915 ENOG4105N5T Radical SAM Protein BA058_09920 ENOG4105CBC glutamate synthase BA058_09925 ENOG4105BZ8 glutamate synthase BA058_09930 ENOG4105DFS Conserved Protein BA058_09935 ENOG4108R66 Conserved Protein BA058_09940 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) BA058_09950 ENOG4105JHE Major Facilitator Superfamily BA058_09965 ENOG4105KB2 stringent starvation protein b BA058_09970 ENOG4107MKT Stringent starvation protein a BA058_09975 ENOG4108UJD 30S ribosomal protein S9 BA058_09985 ENOG4105D6Z AFG1 family ATPase BA058_09990 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BA058_09995 ENOG4105C0H protease BA058_10000 ENOG4105C0H protease BA058_10005 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BA058_10015 ENOG4105RID UPF0379 protein yhcN BA058_10020 ENOG4105UNR (Barnase) inhibitor BA058_10025 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) BA058_10040 ENOG4105CR8 Transcriptional regulator BA058_10045 ENOG4105D1U peptidase U62 modulator of DNA gyrase BA058_10050 ENOG4105QD6 exported protein BA058_10055 ENOG4105C03 ribonuclease BA058_10060 ENOG4108Z03 MAF-like protein BA058_10065 ENOG4105VQ7 Rod shape-determining protein MreD BA058_10070 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BA058_10075 ENOG4105DFF Rod shape-determining protein mreb BA058_10085 ENOG41062P1 Diguanylate cyclase phosphodiesterase BA058_10090 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BA058_10105 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BA058_10110 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BA058_10120 ENOG4107UEK pfkb domain protein BA058_10125 ENOG4105CNN ABC, transporter BA058_10130 ENOG4105C2J ABC transporter BA058_10135 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BA058_10140 ENOG4105D2N Aldolase BA058_10145 ENOG4105E98 transcriptional regulator DeoR family BA058_10150 ENOG4107UEK pfkb domain protein BA058_10155 ENOG4105RG0 Membrane BA058_10160 ENOG4108IA2 Sodium pantothenate symporter BA058_10170 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BA058_10175 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BA058_10180 ENOG4105CEC DNA methylase N-4 N-6 BA058_10185 ENOG41061ME transport protein BA058_10190 ENOG4108XG4 DNA-binding transcriptional regulator BA058_10195 ENOG4105C1P efflux transporter, rnd family, mfp subunit BA058_10200 ENOG4105BZS acriflavin resistance protein BA058_10210 ENOG4105XCM membrane LIPOPROTEIN BA058_10225 ENOG4105EZ7 amino acid ABC transporter BA058_10230 ENOG4105DRP amino acid AbC transporter BA058_10235 ENOG4105CDA abc transporter atp-binding protein BA058_10275 ENOG4108Z0R Transferase BA058_10280 ENOG4105SG3 Protein of unknown function (DUF1488) BA058_10285 ENOG4105E2X shikimate dehydrogenase BA058_10295 ENOG4108WI1 Dna topoisomerase BA058_10305 ENOG4105C79 DNA protecting protein DprA BA058_10315 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BA058_10325 ENOG4105C1A potassium transporter peripheral membrane BA058_10335 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BA058_10340 ENOG4105W1Y Transcriptional regulator BA058_10345 ENOG4105VTS DnaJ-like, subfamily C BA058_10355 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BA058_10360 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BA058_10370 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BA058_10375 ENOG41067V7 50S ribosomal protein L36 BA058_10380 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BA058_10385 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BA058_10395 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BA058_10400 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BA058_10410 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BA058_10435 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BA058_10445 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BA058_10450 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BA058_10455 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BA058_10460 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BA058_10470 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BA058_10475 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BA058_10490 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication BA058_10495 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression BA058_10500 ENOG4107KSE General secretion pathway protein C BA058_10505 ENOG4105GVR general secretion pathway protein D BA058_10510 ENOG4107QHF type ii secretion system protein e BA058_10515 ENOG4105D7Q type ii secretion system BA058_10520 ENOG4108VAU general secretion pathway protein G BA058_10525 ENOG41069X0 general secretion pathway protein h BA058_10540 ENOG4105R04 type II secretion system protein K BA058_10545 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) BA058_10555 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) BA058_10560 ENOG4108UQY Iron-storage protein BA058_10565 ENOG4105W53 bacterioferritin-associated ferredoxin BA058_10570 ENOG4108NNZ chitinase BA058_10610 ENOG4105WWK YheO domain protein BA058_10615 ENOG4108V1T peptidylprolyl cis-trans isomerase BA058_10625 ENOG4108YZY peptidylprolyl cis-trans isomerase BA058_10630 ENOG4105VKU nucleicacid-binding protein BA058_10640 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BA058_10645 ENOG4105C5H ABC transporter BA058_10650 ENOG4105DNZ Alpha Beta Hydrolase BA058_10660 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BA058_10665 ENOG4108UKZ OsmC family BA058_10675 ENOG4107RYR Transcriptional regulator, Crp Fnr family BA058_10680 ENOG410613R integral membrane protein, YccS YhfK family BA058_10685 ENOG4105C8Y Acetylornithine aminotransferase BA058_10690 ENOG4105DDQ anthranilate synthase BA058_10695 ENOG4105MZU cell filamentation protein BA058_10700 ENOG4106195 uncharacterized protein yhfG BA058_10705 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BA058_10715 ENOG4107QZF nitrite reductase NADPH large subunit BA058_10720 ENOG4105WZK nitrite reductase NADPH small subunit BA058_10725 ENOG4107V9H nitrite transporter BA058_10730 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BA058_10735 ENOG4105VYH BA058_10740 ENOG4106PKC pyridoxal phosphate binding BA058_10745 ENOG4106M0N transport system permease protein BA058_10750 ENOG4105MUZ Protein of unknown function DUF2620 BA058_10755 ENOG41080QX K07048 phosphotriesterase-related protein BA058_10760 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BA058_10765 ENOG4108626 Racemase BA058_10770 ENOG4105RMW regulation of transcription, DNA-dependent BA058_10775 ENOG4108M21 BA058_10780 ENOG4105C31 Tryptophanyl-tRNA synthetase BA058_10785 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BA058_10790 ENOG4105DJV ribulose-phosphate 3-epimerase BA058_10795 ENOG4105DFE Dna adenine methylase BA058_10800 ENOG4105EGB membrane protein DamX BA058_10815 ENOG4105E4G Type IV pilus BA058_10820 ENOG4105ITY Required for the use of extracellular DNA as a nutrient BA058_10825 ENOG4105XPX DNA utilization protein HofO BA058_10830 ENOG41065NF Fimbrial assembly family protein BA058_10835 ENOG4108U1Q Pilus assembly protein BA058_10840 ENOG4108JQC penicillin-binding protein 1A BA058_10845 ENOG4107RK2 ADP-ribose diphosphatase NudE BA058_10850 ENOG4105DQY intracellular growth attenuator BA058_10855 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BA058_10860 ENOG4105VEJ Heat shock protein BA058_10885 ENOG4105E0F Histidine kinase BA058_10890 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA058_10895 ENOG4108RRZ Transcription elongation factor GreB BA058_10900 ENOG4105BZM domain protein BA058_10905 ENOG4105XFK Ferrous iron transport protein A BA058_10910 ENOG4105CE1 Ferrous iron transport protein b BA058_10920 ENOG4105DNE Transposase BA058_10925 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BA058_10930 ENOG4105MJ2 Competence protein BA058_10940 ENOG4105C6Z Gluconate BA058_10945 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BA058_10950 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BA058_10955 ENOG41061ZR Transcriptional regulator BA058_10960 ENOG4105CKX Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP BA058_10965 ENOG4105E0Y RtcB Protein BA058_10970 ENOG4105CYB regulatoR BA058_10975 ENOG4105E98 transcriptional regulator DeoR family BA058_10990 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BA058_11010 ENOG4105MHR Fimbrial protein BA058_11015 ENOG4108AF8 Chaperone BA058_11020 ENOG4108RQP Major type 1 subunit fimbrin BA058_11030 ENOG4105CW0 outer membrane usher protein BA058_11035 ENOG4108NAE Fimbrial chaperone protein BA058_11045 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BA058_11060 ENOG4108IUM Glycogen debranching enzyme BA058_11065 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BA058_11070 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA058_11075 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BA058_11085 ENOG4105C9U ATP-dependent DNA helicase RecQ BA058_11090 ENOG4105C6Z Gluconate BA058_11095 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BA058_11100 ENOG4105DIQ Transcriptional regulator BA058_11105 ENOG4105C2I pirin domain protein BA058_11110 ENOG4105D9R oxidoreductase BA058_11120 ENOG4105WCN acetyltransferase BA058_11125 ENOG4105GMB type VI secretion system effector, hcp1 family BA058_11135 ENOG4106FA4 BA058_11140 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BA058_11145 ENOG4105WC8 Conserved Protein BA058_11150 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BA058_11155 ENOG4108IJ9 (ABC) transporter BA058_11165 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component BA058_11170 ENOG4105BZ7 extracellular solute-binding protein family 1 BA058_11180 ENOG4108IV0 ABC, transporter BA058_11185 ENOG4105C0Z ABC transporter BA058_11190 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BA058_11195 ENOG4105C32 Amino acid ABC transporter (Permease) BA058_11200 ENOG4105CP9 extracellular ligand-binding receptor BA058_11205 ENOG4105U59 -acetyltransferase BA058_11215 ENOG4105CP9 extracellular ligand-binding receptor BA058_11220 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA058_11225 ENOG4105CRP Part of the ABC transporter FtsEX involved in BA058_11230 ENOG4105CAK Cell division ATP-binding protein ftsE BA058_11235 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BA058_11240 ENOG4106H78 methyltransferase BA058_11245 ENOG4105MG3 Membrane BA058_11255 ENOG4107FS9 Membrane BA058_11270 ENOG4105EX9 Membrane BA058_11275 ENOG4108W1V Lipoprotein BA058_11280 ENOG4105F9N Major Facilitator Superfamily BA058_11285 ENOG4105DSF transport protein BA058_11290 ENOG4107YAK holo-(acyl carrier protein) synthase 2 BA058_11295 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BA058_11300 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA058_11305 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA058_11310 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BA058_11315 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BA058_11320 ENOG4105MRR Transcriptional regulator (By similarity) BA058_11325 ENOG4105CMI transporter BA058_11330 ENOG4105CJ1 ABC, transporter BA058_11335 ENOG4105D0S secretion protein (HlyD BA058_11340 ENOG4107UNS conserved inner membrane protein BA058_11345 ENOG4105CBX hi0933 family BA058_11350 ENOG4105CJ3 phosphate transporter BA058_11360 ENOG4108M6U Universal stress protein A BA058_11365 ENOG4105DUX Transporter BA058_11375 ENOG4105DGW oligopeptidase A BA058_11380 ENOG4105D6S protein involved in catabolism of external DNA BA058_11385 ENOG4105DC8 reductase BA058_11400 ENOG4105K89 arsenate reductase BA058_11405 ENOG4105Y4Z Outer Membrane Lipoprotein BA058_11415 ENOG4106QJH hemin transport protein BA058_11420 ENOG4107ENK receptor BA058_11435 ENOG4105D4P Coproporphyrinogen iii oxidase BA058_11440 ENOG41090JE Utilization Protein BA058_11450 ENOG4105EHG Permease protein BA058_11455 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BA058_11460 ENOG4105KT7 mgtC SapB transporter BA058_11465 ENOG4105XXV Acid-resistance protein BA058_11470 ENOG41060V2 Acid-resistance protein BA058_11475 ENOG4108YK4 Acid-resistance membrane protein BA058_11480 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci BA058_11490 ENOG4105C1P efflux transporter, rnd family, mfp subunit BA058_11495 ENOG4105BZS acriflavin resistance protein BA058_11500 ENOG4105D3F AraC Family Transcriptional Regulator BA058_11510 ENOG4105CVK Glutamate decarboxylase BA058_11515 ENOG4105CA0 peroxidase BA058_11525 ENOG4106S2D Transcriptional regulator BA058_11530 ENOG4105CBN LysR family transcriptional regulator BA058_11535 ENOG4107H3J ribonuclease BA058_11540 ENOG4105CSH Transporter BA058_11545 ENOG41066T0 asmA family BA058_11550 ENOG4105CMB EAL domain-containing protein BA058_11560 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BA058_11565 ENOG4105CS0 peptidase BA058_11575 ENOG4105BZU Histidine kinase BA058_11580 ENOG4105EJG cellulose synthase BA058_11585 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BA058_11590 ENOG4107EEX Cellulose synthase regulator protein BA058_11595 ENOG4107QZ7 Cellulose synthase catalytic subunit BA058_11605 ENOG410661M cytoplasmic protein BA058_11610 ENOG4105U74 cellulose biosynthesis protein BcsE BA058_11615 ENOG4105WQA Cellulose biosynthesis protein BcsF BA058_11620 ENOG4105D1V cellulose synthase operon protein YhjU BA058_11635 ENOG4105C44 Serine transporter BA058_11640 ENOG4108JQ7 (ABC) transporter BA058_11645 ENOG4105C3U ABC transporter BA058_11650 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA058_11655 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA058_11665 ENOG4105DEF Extracellular solute-binding protein, family 5 BA058_11680 ENOG4105DIJ Phosphoethanolamine transferase BA058_11685 ENOG4105FCD Major Facilitator BA058_11690 ENOG4105EAX Putative lipase BA058_11695 ENOG4108R3E Dna-3-methyladenine glycosylase i BA058_11700 ENOG4105HNP -acetyltransferase BA058_11705 ENOG4107QY8 reductase BA058_11710 ENOG4108ZG0 Ompa motb domain protein BA058_11715 ENOG4105C5I Dehydrogenase BA058_11720 ENOG4106JH6 (LipO)protein BA058_11725 ENOG4105MVF Transcriptional regulator BA058_11730 ENOG4105VEQ Cold shock protein BA058_11735 ENOG41060TC Hok gef cell toxic protein BA058_11745 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BA058_11755 ENOG4105MEV Acyl-transferase BA058_11760 ENOG4108Z12 YiaAB two helix domain-containing protein BA058_11765 ENOG410688U Inner membrane protein yiaB BA058_11770 ENOG4105CMG Carbohydrate kinase BA058_11780 ENOG4105DFW ABC transporter BA058_11785 ENOG4105C2J ABC transporter BA058_11790 ENOG4107RNG ABC transporter BA058_11795 ENOG4105T16 Transcriptional regulator (AraC family) BA058_11800 ENOG4108UR8 BAX protein BA058_11805 ENOG4107T9C Alpha amylase catalytic region BA058_11810 ENOG4105JKW Valine--pyruvate aminotransferase BA058_11820 ENOG4108XIB electron transport protein ysaA BA058_11825 ENOG4105J4Q Transcriptional regulator BA058_11830 ENOG4105DG4 malate L-lactate dehydrogenase BA058_11835 ENOG4108R66 Conserved Protein BA058_11840 ENOG4108M5W BA058_11845 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter BA058_11850 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BA058_11855 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BA058_11860 ENOG4105CMG Carbohydrate kinase BA058_11865 ENOG4105H6Q decarboxylase BA058_11870 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BA058_11875 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BA058_11880 ENOG4105C26 Dehydrogenase BA058_11885 ENOG4105C0A alcohol dehydrogenase BA058_11890 ENOG4105EM7 Selenocysteine-specific translation elongation factor BA058_11895 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) BA058_11900 ENOG4108U78 Glutathione S-transferase BA058_11905 ENOG4105EFX secretion protein, HlyD family BA058_11910 ENOG4105FP6 Protein of unknown function (DUF3302) BA058_11915 ENOG4105CTS PTS system mannitol-specific BA058_11925 ENOG4105E61 Mannitol repressor protein BA058_11930 ENOG41060ND LF82 chromosome, complete sequence BA058_11935 ENOG4108YYI Protein of unknown function (DUF2810) BA058_11940 ENOG4108WY4 inner membrane lipoprotein BA058_11950 ENOG4105DAA L-lactate BA058_11955 ENOG41073TP transcriptional regulator BA058_11965 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BA058_11970 ENOG4105D7W serine acetyltransferase BA058_11985 ENOG4105VW4 glutaredoxin 3 BA058_11990 ENOG4107YZP Rhodanese domain protein BA058_12000 ENOG41063SB peptidase BA058_12005 ENOG4105PXI polysaccharide deacetylase BA058_12010 ENOG4105K64 Glycosyl transferase, family 2 BA058_12020 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BA058_12030 ENOG4105XA0 heptosyltransferase ii BA058_12035 ENOG4105D16 lipopolysaccharide heptosyltransferase i BA058_12040 ENOG41068PG O-Antigen polymerase BA058_12045 ENOG4105K64 Glycosyl transferase, family 2 BA058_12050 ENOG4105X1N Glycosyl transferase family 8 BA058_12060 ENOG4105X1N Glycosyl transferase family 8 BA058_12065 ENOG4106AH0 Glycosyl Transferase BA058_12070 ENOG4107543 (lipo)polysaccharide BA058_12075 ENOG4107RJ7 Glycosyl transferase (Group 1 BA058_12080 ENOG4105DKP glycosyl transferase, family 9 BA058_12085 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BA058_12100 ENOG4105W0E 50S ribosomal protein L33 BA058_12115 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BA058_12135 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BA058_12140 ENOG4105DSJ YicC domain protein BA058_12145 ENOG4105F5P DNA-damage-inducible protein d BA058_12150 ENOG4105EN6 Membrane BA058_12155 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) BA058_12160 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BA058_12165 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BA058_12170 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BA058_12175 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BA058_12180 ENOG4105CB5 ATP-dependent DNA helicase recG BA058_12185 ENOG4105D6U Sodium Glutamate Symporter BA058_12190 ENOG4105C2W permease BA058_12195 ENOG4105JV1 AsmA family BA058_12205 ENOG4105DKQ ROK family BA058_12210 ENOG4105D2N Aldolase BA058_12215 ENOG4105D2N Aldolase BA058_12220 ENOG4105DM4 PTS System BA058_12225 ENOG4108YRF PTS System BA058_12230 ENOG4105DM4 PTS System BA058_12235 ENOG4105ETD TRANSCRIPTIONal BA058_12240 ENOG4105CJQ hydrolase, family 31 BA058_12245 ENOG4105CT4 transporter BA058_12255 ENOG4105DFP Integrase BA058_12335 ENOG4108UZ3 Transporter BA058_12340 ENOG4105D01 (LipO)protein BA058_12350 ENOG4105T8A Uncharacterized protein YicS BA058_12355 ENOG4107RTG Major Facilitator superfamily BA058_12360 ENOG4108SAJ Protein of unknown function (DUF1198) BA058_12365 ENOG4105C7N Xanthine uracil vitamin C permease BA058_12375 ENOG4105CXY transporter BA058_12380 ENOG4105CXY transporter BA058_12385 ENOG4105BZU Histidine kinase BA058_12390 ENOG4108KX4 response regulator BA058_12405 ENOG4105M71 acetolactate synthase 1 regulatory subunit BA058_12410 ENOG4105C7K acetolactate synthase BA058_12420 ENOG4105E5M Multidrug resistance protein D BA058_12425 ENOG4105J13 transcriptional regulator BA058_12430 ENOG4105JP4 Inner membrane protein yidG BA058_12435 ENOG4105VG5 Membrane BA058_12440 ENOG4105CBG Sulfatase BA058_12445 ENOG4107RUZ Sss sodium solute transporter superfamily BA058_12450 ENOG4108AHD Transcriptional regulator BA058_12455 ENOG4105D0C transport protein BA058_12470 ENOG4105R2A (LipO)protein BA058_12475 ENOG4105D99 atp gtp-binding protein BA058_12480 ENOG4107WAP fad NAD(P)-binding domain BA058_12485 ENOG4105DJB Major Facilitator Superfamily BA058_12495 ENOG4108RTU Aldolase BA058_12500 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 BA058_12505 ENOG4105EMF GntR family transcriptional regulator BA058_12510 ENOG410657R replicase EC 2.7 BA058_12515 ENOG410667J hydrolase BA058_12520 ENOG4105VP5 Bacterial protein of unknown function (DUF937) BA058_12530 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA058_12535 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BA058_12540 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BA058_12585 ENOG4108P6C Tryptophan transporter of low affinity BA058_12590 ENOG4105CNH Multidrug resistance protein MdtL BA058_12595 ENOG4105G2Y Transcriptional regulator BA058_12600 ENOG4105E8Q phosphopantetheinyl transferase BA058_12605 ENOG4108YYH Nadph-dependent fmn reductase BA058_12610 ENOG4105C7N Xanthine uracil vitamin C permease BA058_12615 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BA058_12620 ENOG4106HGK Inner membrane protein yieI BA058_12625 ENOG4107VKM 6-phosphogluconolactonase BA058_12635 ENOG4108P68 Outer membrane porin BA058_12640 ENOG4105CS2 ec 3.2.1.21 BA058_12645 ENOG4105C5Y PTS System BA058_12650 ENOG4105CID antiterminator BA058_12655 ENOG4108UTW Plays a role in the regulation of phosphate uptake BA058_12660 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BA058_12665 ENOG4105E2Z phosphate ABC transporter (Permease BA058_12670 ENOG4105C8U phosphate abc transporter BA058_12675 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BA058_12680 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BA058_12685 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BA058_12720 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BA058_12730 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BA058_12745 ENOG4105QTB Flavodoxin BA058_12750 ENOG4108VVK transcriptional Regulator, AsnC BA058_12760 ENOG4105EV2 VWA domain protein interacting with AAA ATPase BA058_12780 ENOG4105C2J ABC transporter BA058_12785 ENOG4105CNN ABC, transporter BA058_12790 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BA058_12795 ENOG4108RVA ribokinase BA058_12800 ENOG4105ETE Transcriptional regulator (LacI family BA058_12805 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA058_12810 ENOG4107EJG GntR family transcriptional regulator BA058_12850 ENOG4108WFC UPF0438 protein yifE BA058_12855 ENOG4105C0P Mg chelatase subunit ChlI BA058_12870 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BA058_12875 ENOG4105CM2 brancheD-chain amino acid aminotransferase BA058_12885 ENOG4105C7B Threonine dehydratase BA058_12890 ENOG4105EMY transcriptional regulator BA058_12900 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BA058_12905 ENOG4105C4R Atp-dependent dna helicase BA058_12920 ENOG4105K63 Thioredoxin BA058_12940 ENOG4105ESV Glycosyl transferase, family 4 BA058_12945 ENOG4105SFE lipopolysaccharide biosynthesis protein BA058_12950 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BA058_12955 ENOG4108IJ1 Dehydrogenase BA058_12960 ENOG4105C1B dTDP-glucose 4-6-dehydratase BA058_12965 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BA058_12970 ENOG4108WJ1 acetyltransferase BA058_12975 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BA058_12980 ENOG4105EGZ biosynthesis protein BA058_12985 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) BA058_13000 ENOG4105C85 amino acid BA058_13025 ENOG4105C4X radical SAM domain protein BA058_13030 ENOG4105ENH Sulfatase BA058_13035 ENOG410601J HemY protein BA058_13040 ENOG4105ECF c-methyltransferase BA058_13045 ENOG41076E6 Uroporphyrinogen-III Synthase BA058_13050 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BA058_13055 ENOG4107T0K Adenylate cyclase BA058_13065 ENOG4105S7Z (LipO)protein BA058_13075 ENOG4105CT0 Protein of unknown function, DUF484 BA058_13085 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BA058_13090 ENOG4105C4R Atp-dependent dna helicase BA058_13095 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase BA058_13100 ENOG4108T58 Mg2 transport protein CorA BA058_13110 ENOG4107QUT magnesium and cobalt transport protein CorA BA058_13125 ENOG4105FR1 rard protein BA058_13130 ENOG4108VUY thioesterase Superfamily protein BA058_13135 ENOG4105HDD phospholipase BA058_13140 ENOG4105C9U ATP-dependent DNA helicase RecQ BA058_13155 ENOG4108EUD Lysophospholipase BA058_13160 ENOG4105DQF Hydrolase BA058_13165 ENOG4105EMK carboxylate amino acid amine transporter BA058_13170 ENOG4105DZ2 Transcriptional regulator BA058_13190 ENOG4105GMB type VI secretion system effector, hcp1 family BA058_13205 ENOG4105CV1 Transketolase (EC 2.2.1.1) BA058_13210 ENOG4106KNT transcriptional regulator BA058_13215 ENOG4105F52 Transcriptional regulator BA058_13220 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin BA058_13230 ENOG4105C5B carbamate kinase BA058_13235 ENOG4107REC cytoplasmic protein BA058_13240 ENOG4107R1Q Membrane protein FdrA BA058_13250 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BA058_13260 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BA058_13265 ENOG4108I5U Uridine phosphorylase BA058_13280 ENOG4105JN3 extra-cytoplasmic solute receptor family protein BA058_13285 ENOG4108RTU Aldolase BA058_13290 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 BA058_13295 ENOG4107HP6 Transcriptional regulator BA058_13300 ENOG4105CGY Dna recombination protein BA058_13310 ENOG4105JC1 sterol-binding domain protein BA058_13320 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BA058_13325 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) BA058_13330 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BA058_13340 ENOG4105MDZ Transcriptional activator rfaH BA058_13345 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BA058_13350 ENOG4107QK7 reductase BA058_13360 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA058_13370 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BA058_13375 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BA058_13380 ENOG4108RR8 protoporphyrinogen oxidase BA058_13410 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BA058_13415 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BA058_13420 ENOG4105PC1 Conserved Protein BA058_13425 ENOG4105E27 serine threonine protein kinase BA058_13440 ENOG4106HNH Acyl-transferase BA058_13450 ENOG4105C2M dna polymerase I BA058_13460 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) BA058_13465 ENOG4105D4P Coproporphyrinogen iii oxidase BA058_13470 ENOG4106FIY BA058_13475 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA058_13480 ENOG4105CUX Signal transduction histidine kinase BA058_13485 ENOG4105C5F glutamine synthetase BA058_13500 ENOG4108K85 Transcriptional regulator BA058_13505 ENOG4108KHF Resistance protein BA058_13510 ENOG4105R9B Major Facilitator BA058_13515 ENOG4105E98 transcriptional regulator DeoR family BA058_13520 ENOG4108MGF sugar kinase BA058_13525 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA058_13530 ENOG4105D2M Aldolase BA058_13535 ENOG4105CPQ Dehydrogenase BA058_13545 ENOG4105CSH Transporter BA058_13555 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BA058_13570 ENOG4105SUU thioesterase domain BA058_13580 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system BA058_13605 ENOG4108MG3 formate dehydrogenase BA058_13610 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BA058_13615 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_13620 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_13625 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BA058_13655 ENOG4105DET Rhamnulokinase BA058_13680 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA058_13695 ENOG4108RPX mosc domain containing protein BA058_13700 ENOG4105E0F Histidine kinase BA058_13705 ENOG4105E3W Two component transcriptional regulator (Winged helix family BA058_13710 ENOG4105FMW periplasmic BA058_13725 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BA058_13740 ENOG4105EBK exported protein BA058_13745 ENOG4108VTS Membrane BA058_13750 ENOG41065TG regulatoR BA058_13760 ENOG4105DP0 ferredoxin-NADP reductase BA058_13765 ENOG4105CBT Fructose-1,6-bisphosphatase BA058_13775 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BA058_13790 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BA058_13805 ENOG41063M6 Cell Division Protein BA058_13810 ENOG4105ETE Transcriptional regulator (LacI family BA058_13815 ENOG4105C25 Primosomal protein n' BA058_13825 ENOG4107S01 Repressor protein MetJ BA058_13835 ENOG4105C28 cystathionine BA058_13840 ENOG4105CFH Aspartokinase BA058_13845 ENOG4105DRB nucleoside-specific channel-forming protein BA058_13855 ENOG4105CGH 5'-nucleotidase BA058_13865 ENOG4105CGH 5'-nucleotidase BA058_13870 ENOG4105SYT Methylenetetrahydrofolate reductase BA058_13880 ENOG4108Q5Y Membrane BA058_13885 ENOG4108XC3 NADH ubiquinone oxidoreductase BA058_13895 ENOG4105DCT glycerol dehydrogenase BA058_13900 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA058_13905 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA058_13910 ENOG4105DM4 PTS System BA058_13915 ENOG4108YRF PTS System BA058_13920 ENOG4105C6N Formate acetyltransferase BA058_13925 ENOG4108AHH pyruvate formate lyase II activase BA058_13930 ENOG4108XCZ PTS System BA058_13935 ENOG4106R3P AraC family transcriptional regulator BA058_13940 ENOG4105DIJ Phosphoethanolamine transferase BA058_13955 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BA058_13960 ENOG4105CAS nag kinase BA058_13970 ENOG4105CXK mandelate racemase muconate lactonizing BA058_13975 ENOG4108I5G Major Facilitator superfamily BA058_13980 ENOG4105C5Q Transcriptional regulator BA058_13985 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BA058_13990 ENOG4105CH2 amidohydrolase BA058_14005 ENOG4108Y73 Membrane BA058_14015 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BA058_14045 ENOG4105D4A Cell wall formation (By similarity) BA058_14050 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BA058_14090 ENOG4105PM1 preprotein translocase subunit SecE BA058_14095 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BA058_14130 ENOG4105D41 biosynthesis protein thiH BA058_14140 ENOG4105WHD thiamine biosynthesis protein ThiS BA058_14145 ENOG4105D06 uba thif-type nad fad binding protein BA058_14150 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BA058_14155 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BA058_14170 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BA058_14180 ENOG4105R2J Conserved Protein BA058_14185 ENOG4105K70 DNA-binding protein BA058_14190 ENOG4108T8B Protein of unknown function (DUF1481) BA058_14195 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism BA058_14200 ENOG4105BZU Histidine kinase BA058_14205 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA058_14210 ENOG4105C12 Phosphoribosylglycinamide synthetase BA058_14240 ENOG41062WK cellular response to acidity BA058_14245 ENOG4105K5X acetyltransferase BA058_14255 ENOG4107QP3 malate synthase g BA058_14260 ENOG4108I9X Isocitrate lyase BA058_14270 ENOG41069M3 Transcriptional regulator BA058_14275 ENOG4105C3R Methionine synthase BA058_14290 ENOG4105EAM Na Pi-cotransporter BA058_14295 ENOG4105EQ6 Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity) BA058_14305 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein BA058_14310 ENOG4105F3R pts system mannose fructose sorbose family iid BA058_14315 ENOG4105ETZ PTS System BA058_14320 ENOG4105KPI PTS system sorbose subfamily IIB component BA058_14325 ENOG4108XCU pts system BA058_14330 ENOG4105CHR reductase BA058_14335 ENOG4105DKT Transcriptional regulator BA058_14340 ENOG4105FE9 pseudouridine synthase BA058_14345 ENOG4108ZR5 Conserved Protein BA058_14350 ENOG4105CFH Aspartokinase BA058_14365 ENOG4108MDC (LipO)protein BA058_14370 ENOG4108Q9C Periplasmic Protein BA058_14375 ENOG4105E3R (LipO)protein BA058_14395 ENOG4105EG2 ABC transporter, permease BA058_14400 ENOG4105D56 permease protein BA058_14405 ENOG4107FKK extracellular solute-binding protein family 1 BA058_14415 ENOG4108IJ9 (ABC) transporter BA058_14420 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) BA058_14425 ENOG4107W52 maltose operon periplasmic protein BA058_14445 ENOG41080IJ Diacylglycerol kinase BA058_14455 ENOG4107R73 Mate efflux family protein BA058_14460 ENOG4105VDW Csbd family BA058_14465 ENOG4105MYN Zinc uptake regulation protein BA058_14520 ENOG41077V0 CPS-53 (KpLE1) prophage BA058_14525 ENOG4108R7K Metal Dependent Phosphohydrolase BA058_14530 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) BA058_14535 ENOG4105H40 BA058_14550 ENOG4108XTP Transcriptional regulator BA058_14560 ENOG4108S1U BA058_14570 ENOG4105YQ0 BA058_14580 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BA058_14585 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) BA058_14595 ENOG4108MXB Protein of unknown function (DUF968) BA058_14600 ENOG4105HGD Antitermination protein BA058_14615 ENOG4105NVB glycoside hydrolase, family 19 BA058_14640 ENOG4105CAR Terminase, large subunit BA058_14685 ENOG4105TKZ Tail Sheath BA058_14710 ENOG4108NKR DNA circulation protein BA058_14730 ENOG4108T86 baseplate J family protein BA058_14735 ENOG4105Y0G tail protein BA058_14740 ENOG4105Y9F tail fiber protein BA058_14745 ENOG4105PTU response to oxidative stress BA058_14750 ENOG4106FE3 DNA repair BA058_14760 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BA058_14765 ENOG4105P4Z Phage shock protein G BA058_14770 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BA058_14775 ENOG4105CDU Replicative dna helicase BA058_14785 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA058_14790 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BA058_14795 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BA058_14800 ENOG4105CGF Aromatic amino acid aminotransferase BA058_14805 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BA058_14810 ENOG4105C7S Dehydrogenase BA058_14815 ENOG4107QN2 dihydrolipoyl dehydrogenase BA058_14820 ENOG4105CMV Succinyl-CoA synthetase subunit beta BA058_14825 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BA058_14830 ENOG4107QPK )-transporter BA058_14835 ENOG4105DG4 malate L-lactate dehydrogenase BA058_14840 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA058_14845 ENOG4105CQZ Histidine kinase BA058_14850 ENOG4105F0S class B acid phosphatase BA058_14855 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BA058_14860 ENOG4105MSB protein, conserved in bacteria BA058_14865 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BA058_14870 ENOG4108UUM single-stranded DNA-binding protein BA058_14875 ENOG4105PMV Membrane BA058_14880 ENOG4108M8H domain protein BA058_14885 ENOG4108W3Q Transcriptional regulator BA058_14890 ENOG4108Z4X TRANSCRIPTIONal BA058_14895 ENOG4105C7N Xanthine uracil vitamin C permease BA058_14900 ENOG4105EEQ Na H antiporter BA058_14915 ENOG41067MG lrgb family BA058_14925 ENOG41062QD Membrane BA058_14930 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA058_14940 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit BA058_14945 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BA058_14950 ENOG4105DVI reductase, NrfD BA058_14955 ENOG4108QKW cytochrome c-type biogenesis protein BA058_14965 ENOG4108W0S formate-dependent nitrite reductase complex BA058_14970 ENOG4105CK2 sodium dicarboxylate symporter BA058_14975 ENOG4105Y25 Transposase BA058_14980 ENOG4105DQ6 Transposase BA058_14985 ENOG41082ND Uncharacterized protein yjcO BA058_14990 ENOG4108JQ7 (ABC) transporter BA058_14995 ENOG4105C3U ABC transporter BA058_15000 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA058_15005 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA058_15015 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_15020 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_15025 ENOG4105ETP RND efflux system, outer membrane lipoprotein BA058_15030 ENOG4108MI0 Resistance protein BA058_15035 ENOG4105J12 Multidrug resistance protein mdtN BA058_15045 ENOG4105EUZ Beta-lactamase domain protein BA058_15050 ENOG4107TFG D-allose kinase BA058_15055 ENOG4105UP7 3-epimerase BA058_15060 ENOG4105CNN ABC, transporter BA058_15065 ENOG4105C2J ABC transporter BA058_15070 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BA058_15075 ENOG4105NYY transcriptional regulator, RpiR BA058_15080 ENOG4108YZG isomerase BA058_15085 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 BA058_15090 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BA058_15095 ENOG410849A acetyltransferase, (GNAT) family BA058_15105 ENOG4105FD8 phosphonate metabolism protein PhnM BA058_15110 ENOG4105HRV phosphonate c-p lyase system protein phnl BA058_15115 ENOG4105ENV phosphonate C-P lyase system protein PhnK BA058_15120 ENOG4105FT8 Phosphonate metabolism BA058_15125 ENOG4105EKV Phosphonate metabolism protein BA058_15130 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BA058_15135 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BA058_15140 ENOG4107RJJ Transcriptional regulator BA058_15150 ENOG4105EHI Phosphonate ABC transporter, periplasmic BA058_15155 ENOG4105D5T phosphonate abc transporter BA058_15160 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase BA058_15165 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BA058_15170 ENOG4108F5E vimentin BA058_15175 ENOG4108YIV BA058_15180 ENOG4105CSH Transporter BA058_15190 ENOG4105ECM Sensor protein basS pmrB BA058_15195 ENOG4105XJC Two component transcriptional regulator (Winged helix family BA058_15200 ENOG4105DIJ Phosphoethanolamine transferase BA058_15205 ENOG4105D5Q Arginine ornithine antiporter BA058_15210 ENOG4106ZGR Transcriptional regulator BA058_15215 ENOG4105CXN decarboxylase BA058_15220 ENOG4108K2B transcriptional regulator BA058_15230 ENOG4105F8D glycoside hydrolase family 4 BA058_15235 ENOG4108R5S membrane BA058_15240 ENOG4107GFK fumarate BA058_15245 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BA058_15255 ENOG4108MRH transcriptional regulatory protein BA058_15260 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BA058_15265 ENOG4105VR1 Pfam:DUF1271 BA058_15270 ENOG410830R acetyltransferase BA058_15285 ENOG4105CRK lysyL-tRNA synthetase BA058_15290 ENOG4105DUX Transporter BA058_15295 ENOG4105CXN decarboxylase BA058_15300 ENOG4105D5Q Arginine ornithine antiporter BA058_15305 ENOG4108M3R transcriptional activator CadC BA058_15320 ENOG4108SIC Transcriptional regulator BA058_15325 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BA058_15335 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BA058_15340 ENOG4108IJ0 Aspartate ammonia-lyase BA058_15345 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 BA058_15350 ENOG4105DVH amino acid BA058_15360 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BA058_15365 ENOG4108ZVF (LipO)protein BA058_15370 ENOG4105MTB Uncharacterized protein YjeJ BA058_15375 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BA058_15385 ENOG4106HKS Entericidin EcnA/B family BA058_15390 ENOG4106BSU Entericidin B BA058_15395 ENOG4105KPY Small multidrug resistance protein BA058_15400 ENOG4105QNF Outer membrane lipoprotein BA058_15405 ENOG41066YJ Beta-lactamase BA058_15420 ENOG4105E33 succinate dehydrogenase BA058_15425 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BA058_15435 ENOG4107SC7 Inner membrane transporter yjeM BA058_15440 ENOG4105EGS Mechanosensitive ion channel BA058_15475 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BA058_15480 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BA058_15485 ENOG4105K8N protein family UPF0079, ATPase BA058_15490 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BA058_15505 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BA058_15510 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BA058_15515 ENOG4107QJR hflk protein BA058_15520 ENOG4105EPW hflc protein BA058_15540 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BA058_15545 ENOG4105C2N RNA methyltransferase TrmH family group 3 BA058_15550 ENOG4105FUX Conserved Protein BA058_15555 ENOG4108P9J Phage shock protein A BA058_15560 ENOG4107VNS Protein of unknown function (DUF2491) BA058_15565 ENOG4105Z6B inner membrane protein yjfl BA058_15570 ENOG4108KXT Conserved Protein BA058_15575 ENOG4106032 Glutathionylspermidine synthase BA058_15580 ENOG4105CSU acyl-Coa dehydrogenase BA058_15585 ENOG4105S17 UPF0379 protein yjfN BA058_15590 ENOG4105WSB biofilm stress and motility protein A BA058_15595 ENOG4108MXZ Esterase BA058_15610 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BA058_15615 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport BA058_15635 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BA058_15640 ENOG4105KIT UPF0379 protein yjfY BA058_15660 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BA058_15680 ENOG4105DPW Major facilitator superfamily MFS_1 BA058_15685 ENOG4107S3R L-aspartate oxidase BA058_15690 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) BA058_15695 ENOG4105E39 Enoyl-CoA hydratase BA058_15705 ENOG4105CHR reductase BA058_15715 ENOG4105FHY Opacity-associated protein A BA058_15720 ENOG4108V1T peptidylprolyl cis-trans isomerase BA058_15730 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BA058_15735 ENOG4105DXC membrane BA058_15740 ENOG4105ECR NmrA family BA058_15745 ENOG4105KVH Transcriptional regulator BA058_15750 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BA058_15755 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BA058_15760 ENOG4108UUE Transcriptional regulator BA058_15765 ENOG41061GZ Protein of unknown function (DUF1107) BA058_15770 ENOG4105C37 (CBS) domain BA058_15775 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BA058_15785 ENOG4105CFU surface antigen BA058_15790 ENOG4105MA0 exported protein BA058_15795 ENOG4108ZHD aig2 family BA058_15800 ENOG4105F0N pyrophosphate phospho-hydrolase BA058_15805 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BA058_15810 ENOG4105C2J ABC transporter BA058_15815 ENOG4107R9N ABC transporter BA058_15820 ENOG41062B0 ABC transporter, permease BA058_15830 ENOG4105DFU Cell wall formation (By similarity) BA058_15840 ENOG4105CMS peptidase U62, modulator of DNA gyrase BA058_15845 ENOG4108XVM Cytochrome b(562) BA058_15850 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BA058_15855 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BA058_15865 ENOG4105CG3 alpha amylase, catalytic region BA058_15870 ENOG4105C5Y PTS System BA058_15875 ENOG4105D4X repressor BA058_15880 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BA058_15885 ENOG4105KME endoribonuclease L-psp BA058_15900 ENOG41077AM PyrBI operon attenuator BA058_15910 ENOG4105CSX c4-dicarboxylate anaerobic carrier BA058_15915 ENOG4105DBV ornithine carbamoyltransferase BA058_15930 ENOG4105XEP YhcH YjgK YiaL family protein BA058_15935 ENOG4105DBV ornithine carbamoyltransferase BA058_15940 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BA058_15945 ENOG4108MJ3 acetyltransferase BA058_15950 ENOG4108M3P Membrane BA058_15955 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BA058_15960 ENOG4105MYG DNA polymerase iii, chi subunit BA058_15970 ENOG4108M8S permease YjgP YjgQ family protein BA058_15975 ENOG4108K5H permease YjgP YjgQ family protein BA058_15980 ENOG4105D7A ATP-binding protein BA058_15985 ENOG4105K2J Transcriptional regulator BA058_15990 ENOG4105C6Z Gluconate BA058_15995 ENOG4105CHR reductase BA058_16000 ENOG4105CPQ Dehydrogenase BA058_16005 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BA058_16010 ENOG4105DQ4 alcohol dehydrogenase BA058_16030 ENOG4108I6E Sulfatase BA058_16035 ENOG4105T40 surface antigen msp4 family protein BA058_16050 ENOG41067TZ transcriptional regulator, MarR family BA058_16070 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR BA058_16080 ENOG4106P2F Pfam:Pili_assembly_C BA058_16085 ENOG4106PG1 outer membrane usher protein BA058_16090 ENOG4108ZJG MrfB protein BA058_16155 ENOG4108SB3 DoxX Family BA058_16170 ENOG4108R86 Transcriptional regulator BA058_16175 ENOG4105E5H Transposase BA058_16180 ENOG4108YXQ IS66 Orf2 family protein BA058_16200 ENOG41090WB Transposase is3 is911 BA058_16205 ENOG4108J1Q BA058_16225 ENOG4105C42 Type I secretion membrane fusion protein (HlyD BA058_16230 ENOG4108JJA ABC, transporter BA058_16235 ENOG4107V48 Hemolysin-type calcium-binding BA058_16240 ENOG4108RC6 RTX toxin BA058_16255 ENOG4108S1C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) BA058_16260 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA058_16265 ENOG4105ES5 Histidine kinase BA058_16290 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BA058_16295 ENOG4105NI8 Cytosine-specific methyltransferase BA058_16320 ENOG4105E5H Transposase BA058_16325 ENOG4106QAN BA058_16330 ENOG4105CKT filamentous hemagglutinin BA058_16335 ENOG4105D5K Hemolysin activator protein BA058_16370 ENOG4105BZC d-serine deaminase BA058_16380 ENOG4105W8I Transcriptional regulator BA058_16390 ENOG410814C multidrug resistance protein BA058_16405 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) BA058_16410 ENOG4105KNY Microcompartments protein BA058_16415 ENOG4105F1A Pyruvate formate-lyase BA058_16420 ENOG4105C6N Formate acetyltransferase BA058_16425 ENOG4108EKI Dehydrogenase BA058_16435 ENOG4108EKI Dehydrogenase BA058_16440 ENOG4105KNY Microcompartments protein BA058_16445 ENOG4105KNY Microcompartments protein BA058_16450 ENOG4105KNY Microcompartments protein BA058_16485 ENOG4105MP0 transposase BA058_16490 ENOG4105C87 Aminotransferase class I and II BA058_16495 ENOG4105DFD Na H antiporter BA058_16510 ENOG4105DFD Na H antiporter BA058_16515 ENOG4108MVM Transposase BA058_16540 ENOG4105TS0 gtp-binding protein BA058_16550 ENOG4108KZE transcriptional regulator BA058_16565 ENOG4106H6R UPF0380 protein BA058_16570 ENOG4105MFG Antirestriction protein BA058_16575 ENOG4108YGG dna repair protein BA058_16580 ENOG4106WJE Protein of unknown function (DUF987) BA058_16585 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BA058_16630 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria BA058_16645 ENOG4108W9T type 1 fimbriae regulatory protein BA058_16650 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off BA058_16660 ENOG4108RQP Major type 1 subunit fimbrin BA058_16665 ENOG4108S54 Fimbrial protein BA058_16670 ENOG4108NAE Fimbrial chaperone protein BA058_16675 ENOG4105CW0 outer membrane usher protein BA058_16680 ENOG4108SQA Fimbrial BA058_16685 ENOG4108T65 Fimbrial BA058_16690 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin BA058_16705 ENOG4105DEI Mannitol dehydrogenase BA058_16715 ENOG4105C6F GntR Family Transcriptional Regulator BA058_16725 ENOG4106PZD Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway BA058_16730 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA058_16735 ENOG4107YNJ LysR family Transcriptional regulator BA058_16740 ENOG4105DYB Isoaspartyl dipeptidase BA058_16745 ENOG4108P2H Inner membrane protein YjiG BA058_16750 ENOG41074DU domain protein BA058_16755 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) BA058_16760 ENOG4105CBP Major Facilitator BA058_16765 ENOG4108ZK4 sdia-regulated domain-containing protein BA058_16775 ENOG4105CIZ coA-substrate-specific enzyme activase BA058_16780 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase BA058_16785 ENOG4106BRA Membrane BA058_16800 ENOG4105FU6 Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease La (By similarity) BA058_16815 ENOG4108F3G Type I restriction-modification system, R subunit BA058_16825 ENOG4105CKI cobalamin synthesis protein BA058_16830 ENOG4105VCD cytoplasmic protein BA058_16835 ENOG4105D22 carbon starvation protein BA058_16845 ENOG4105C8Q Methyl-accepting chemotaxis BA058_16850 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BA058_16860 ENOG4108ERU trap dicarboxylate transporter subunit DctP BA058_16865 ENOG4105EEQ Na H antiporter BA058_16870 ENOG410617M Transcriptional regulator BA058_16875 ENOG4105CPQ Dehydrogenase BA058_16880 ENOG4107RES phosphoglycerol transferase I BA058_16885 ENOG4105RI1 glycoprotein receptor BA058_16890 ENOG4106CVF DNA replication protein BA058_16905 ENOG4105DWK Membrane BA058_16910 ENOG4108N8T regulatoR BA058_16915 ENOG4108T94 DNA-binding transcriptional activator BglJ BA058_16920 ENOG4108819 ferric iron reductase BA058_16925 ENOG4105YBH Protein of unknown function (DUF1435) BA058_16950 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) BA058_16955 ENOG4108WPU DNA polymerase III subunit psi BA058_16960 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BA058_16965 ENOG4105PAD Hydrolase BA058_16990 ENOG41077V0 CPS-53 (KpLE1) prophage BA058_16995 ENOG4108R7K Metal Dependent Phosphohydrolase BA058_17000 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) BA058_17005 ENOG4105H40 BA058_17030 ENOG4108S1U BA058_17045 ENOG4105YQ0 BA058_17060 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BA058_17065 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) BA058_17075 ENOG4108MXB Protein of unknown function (DUF968) BA058_17115 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BA058_17155 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BA058_17225 ENOG4108X9F tail fiber protein BA058_17250 ENOG4106FE3 DNA repair BA058_17260 ENOG4105K3G Periplasmic Protein BA058_17270 ENOG4108NRW Phospholipase, patatin family BA058_17275 ENOG4105EYA deoxyribonuclease BA058_17280 ENOG41076CZ activating enzyme BA058_17285 ENOG4105G0K glycine radical enzyme YjjI family BA058_17320 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) BA058_17325 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) BA058_17330 ENOG4105EAC phosphoserine phosphatase BA058_17335 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BA058_17340 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BA058_17345 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system BA058_17355 ENOG4105C5H ABC transporter BA058_17360 ENOG4107SC1 transglycosylase BA058_17380 ENOG4105UEI Transcriptional Regulator AraC Family BA058_17385 ENOG4108RH0 Crea protein BA058_17390 ENOG4105E3W Two component transcriptional regulator (Winged helix family BA058_17395 ENOG4105EB3 Histidine kinase BA058_17400 ENOG4105CT7 inner membrane cred family protein BA058_17405 ENOG41065U4 response regulator BA058_17410 ENOG410759A BA058_17415 ENOG4106FVC RNA methyltransferase BA058_17425 ENOG4105CFH Aspartokinase BA058_17430 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BA058_17435 ENOG4105D98 threonine synthase BA058_17445 ENOG41062C6 Protein of unknown function (DUF2502) BA058_17450 ENOG4105D1Q UPF0246 protein BA058_17455 ENOG4105BZG amino acid carrier protein BA058_17460 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA058_17465 ENOG4108RIR Molybdenum cofactor biosynthesis protein BA058_17475 ENOG4106HK8 GPR1 FUN34 yaaH family protein BA058_17480 ENOG4108QUJ UPF0174 protein YaaW BA058_17485 ENOG4108WTA UPF0412 protein YaaI BA058_17510 ENOG41061MV Arylsulfatase BA058_17520 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BA058_17525 ENOG41063Z6 transcriptional regulator, lysR family BA058_17535 ENOG410647N response to DNA damage stimulus BA058_17540 ENOG4105DTN riboflavin biosynthesis protein ribF BA058_17545 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BA058_17550 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BA058_17555 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BA058_17565 ENOG4105DU0 nucleoside hydrolase BA058_17585 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BA058_17590 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BA058_17600 ENOG4108XNW Transcriptional activatory protein CaiF BA058_17610 ENOG4106YT9 Enoyl-CoA hydratase BA058_17615 ENOG4105CEY Amp-dependent synthetase and ligase BA058_17620 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BA058_17625 ENOG4105C1G acyl-Coa dehydrogenase BA058_17640 ENOG4105C10 Electron transfer flavoprotein BA058_17645 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BA058_17650 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein BA058_17655 ENOG4105C54 Major Facilitator superfamily BA058_17660 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF BA058_17665 ENOG4105CKD glutathione-regulated potassium-efflux system protein BA058_17670 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BA058_17705 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BA058_17710 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) BA058_17715 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BA058_17720 ENOG4105D3G Pseudouridine synthase BA058_17730 ENOG4105CQ2 DNA polymerase BA058_17735 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BA058_17745 ENOG4105EF1 ribulokinase BA058_17750 ENOG41063TF transcriptional regulator (AraC BA058_17765 ENOG4108KF1 Membrane BA058_17770 ENOG4107T0D ABC, transporter BA058_17775 ENOG4106SMU thiamine transporter membrane protein BA058_17780 ENOG4105DP9 ABC transporter BA058_17785 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BA058_17795 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BA058_17805 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BA058_17820 ENOG41064T2 transcriptional regulator, lysR family BA058_17825 ENOG4105C7K acetolactate synthase BA058_17830 ENOG4108ZP8 Acetolactate synthase small subunit BA058_17840 ENOG4107B7Y DNA-binding transcriptional regulator FruR BA058_17855 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BA058_17860 ENOG4105CJN penicillin-binding protein BA058_17865 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BA058_17870 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BA058_17880 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BA058_17885 ENOG4105CNI cell division protein FtsW BA058_17895 ENOG4105DFU Cell wall formation (By similarity) BA058_17900 ENOG4105CPF Cell wall formation (By similarity) BA058_17905 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BA058_17910 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BA058_17915 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BA058_17930 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BA058_17935 ENOG4105M6F mutator MutT protein BA058_17950 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BA058_17960 ENOG4105D7Q type ii secretion system BA058_17965 ENOG4107QHF type ii secretion system protein e BA058_17970 ENOG4108ZUW Major pilin subunit BA058_17980 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BA058_17985 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BA058_17990 ENOG4106A72 regulatory protein AmpE BA058_17995 ENOG4105C85 amino acid BA058_18000 ENOG4105GMB type VI secretion system effector, hcp1 family BA058_18005 ENOG41060S4 immunity protein BA058_18015 ENOG41060S4 immunity protein BA058_18025 ENOG41073TP transcriptional regulator BA058_18030 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BA058_18035 ENOG4107QSN dihydrolipoamide acetyltransferase BA058_18040 ENOG4107QN2 dihydrolipoyl dehydrogenase BA058_18045 ENOG4108NST exported protein BA058_18050 ENOG4107QIJ Aconitate hydratase 2 BA058_18055 ENOG4108ZIG UPF0231 protein BA058_18065 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BA058_18070 ENOG4108ZRK uncharacterized protein yacC BA058_18075 ENOG4105E3B Multicopper oxidase BA058_18085 ENOG4105DZG Dehydrogenase BA058_18090 ENOG4108UGV hypoxanthine phosphoribosyltransferase BA058_18095 ENOG41077A9 carbonic anhydrase BA058_18100 ENOG4105DA5 (ABC) transporter BA058_18105 ENOG4105E3A (ABC) transporter BA058_18110 ENOG4108YTN IIa component BA058_18115 ENOG4107BJW polysaccharide deacetylase BA058_18120 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BA058_18125 ENOG4108A32 Transposase BA058_18145 ENOG4105P0Q fimbrial-like protein YadC BA058_18150 ENOG4105SN2 fimbrial-like adhesin protein BA058_18155 ENOG4105SYG Fimbrial protein BA058_18160 ENOG4108XEY fimbrial-like adhesin protein BA058_18165 ENOG4105CW0 outer membrane usher protein BA058_18170 ENOG4108VEV chaperone BA058_18180 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BA058_18185 ENOG4105DJ0 Poly(A) Polymerase BA058_18190 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BA058_18195 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BA058_18205 ENOG4107XID 2'-5' rna ligase BA058_18210 ENOG4105CQ7 ATP-dependent helicase BA058_18215 ENOG4105BZ4 penicillin-binding protein BA058_18220 ENOG4105E0K tonB-dependent siderophore receptor BA058_18225 ENOG4105E0A ABC, transporter BA058_18230 ENOG4105J76 Periplasmic binding protein BA058_18235 ENOG4105S6R Iron-hydroxamate transporter permease subunit BA058_18245 ENOG4105CMQ Chloride channel BA058_18255 ENOG4105EN6 Membrane BA058_18260 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BA058_18275 ENOG4105C0H protease BA058_18280 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BA058_18295 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) BA058_18300 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BA058_18325 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BA058_18330 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BA058_18335 ENOG4105KNE Phosphatidate cytidylyltransferase BA058_18340 ENOG4105DZP Membrane-associated zinc metalloprotease BA058_18350 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BA058_18355 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BA058_18380 ENOG4105C0B DNA polymerase III (alpha subunit) BA058_18390 ENOG4105CXN decarboxylase BA058_18395 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BA058_18400 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BA058_18405 ENOG4105M1T rho-binding antiterminator BA058_18415 ENOG4108VWS Yaeq family BA058_18420 ENOG4108YZN class I peptide chain release factor BA058_18425 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BA058_18430 ENOG4108UY0 (LipO)protein BA058_18440 ENOG4108R96 Methyltransferase, YaeB family BA058_18445 ENOG4108R8X outer membrane lipoprotein BA058_18450 ENOG4105D01 (LipO)protein BA058_18455 ENOG4108UMI ABC transporter, permease BA058_18460 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BA058_18465 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BA058_18500 ENOG4105CV8 reductase BA058_18505 ENOG4105HEI LysR family (Transcriptional regulator BA058_18515 ENOG4105F2W methyltransferase BA058_18520 ENOG4105E9H Lytic Murein transglycosylase BA058_18530 ENOG4105D1A Methyltransferase BA058_18540 ENOG4107RZZ dna polymerase iii epsilon subunit BA058_18550 ENOG410600K aminopeptidase BA058_18580 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BA058_18630 ENOG4108WC9 type VI secretion system effector, hcp1 family BA058_18640 ENOG4105CS6 Rhs element vgr protein BA058_18680 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BA058_18685 ENOG4108WN0 inhibitor of vertebrate lysozyme BA058_18690 ENOG4107QPN acyl-Coa dehydrogenase BA058_18700 ENOG4105E7A Glutamine amidotransferase BA058_18705 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BA058_18710 ENOG4108YS0 lipoprotein YafL BA058_18715 ENOG4108UK5 Transposase BA058_18735 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system BA058_18740 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome BA058_18745 ENOG4108HYG acetyltransferase BA058_18755 ENOG4108S2Y peptide Chain Release factor BA058_18760 ENOG4105CIN aminoacyl-histidine dipeptidase BA058_18770 ENOG4105V1F Fermentation respiration switch protein BA058_18780 ENOG4105FCK Membrane BA058_18790 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BA058_18820 ENOG4108P8R BA058_18870 ENOG41090WB Transposase is3 is911 BA058_18925 ENOG4108S54 Fimbrial protein BA058_18960 ENOG41067TZ transcriptional regulator, MarR family BA058_18965 ENOG4107RNH Outer membrane receptor FepA BA058_18970 ENOG4105NIV Esterase BA058_18975 ENOG4105E93 esterase BA058_18995 ENOG4105VNT transposase (IS4 family) protein BA058_19015 ENOG4107ENK receptor BA058_19025 ENOG4105CKI cobalamin synthesis protein BA058_19030 ENOG4105E5H Transposase BA058_19050 ENOG4108YXQ IS66 Orf2 family protein BA058_19060 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) BA058_19065 ENOG4105CRK lysyL-tRNA synthetase BA058_19075 ENOG4105CXN decarboxylase BA058_19080 ENOG4105D5Q Arginine ornithine antiporter BA058_19100 ENOG4105F4K antigen 43 BA058_19105 ENOG4106H6R UPF0380 protein BA058_19110 ENOG4105MFG Antirestriction protein BA058_19115 ENOG4108YGG dna repair protein BA058_19120 ENOG4106WJE Protein of unknown function (DUF987) BA058_19130 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BA058_19155 ENOG4105F5W AtP-binding protein BA058_19160 ENOG4105D70 Integrase catalytic subunit BA058_19195 ENOG4105R3P Inner membrane protein yagU BA058_19200 ENOG4105PI0 Ferredoxin BA058_19210 ENOG4106PYX Receptor BA058_19215 ENOG4108N3D putative enzyme BA058_19240 ENOG4105NRA 50s ribosomal protein l31 type b BA058_19250 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BA058_19255 ENOG4105ENX hydrolase BA058_19260 ENOG410642W LysR family Transcriptional regulator BA058_19265 ENOG4105EQ2 LysR family Transcriptional regulator BA058_19270 ENOG4107SET aldo keto reductase BA058_19280 ENOG4105TNG K13735 adhesin invasin BA058_19290 ENOG4105CV8 reductase BA058_19295 ENOG4108KBJ Inner membrane protein YkgB BA058_19300 ENOG41066GK UPF0379 protein ykgI BA058_19305 ENOG4107QN2 dihydrolipoyl dehydrogenase BA058_19310 ENOG4108K01 transcriptional regulator BA058_19315 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BA058_19320 ENOG4107QR9 Iron-sulfur cluster binding protein BA058_19325 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BA058_19350 ENOG4105BZU Histidine kinase BA058_19355 ENOG4108W9T type 1 fimbriae regulatory protein BA058_19365 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) BA058_19370 ENOG4105C26 Dehydrogenase BA058_19375 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) BA058_19380 ENOG4105C94 Transporter BA058_19390 ENOG4105BZU Histidine kinase BA058_19395 ENOG4108NUU Transcriptional regulator BA058_19400 ENOG4105SZ2 membrAne BA058_19405 ENOG4107SNB ankyrin repeat protein YahD BA058_19410 ENOG4105N16 Protein of unknown function (DUF2877) BA058_19415 ENOG4107R1Q Membrane protein FdrA BA058_19420 ENOG4107REC cytoplasmic protein BA058_19430 ENOG4105C5B carbamate kinase BA058_19435 ENOG4105DZC cytosine deaminase BA058_19440 ENOG4105DQ4 alcohol dehydrogenase BA058_19450 ENOG4105E82 cytochrome subunit of dehydrogenase BA058_19455 ENOG4105TDT uncharacterized protein yahO BA058_19460 ENOG4108JU7 Transcriptional regulator BA058_19465 ENOG4105CR4 methylisocitrate lyase BA058_19470 ENOG4105BZN citrate synthase BA058_19475 ENOG4105DXD 2-methylcitrate dehydratase BA058_19480 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA058_19485 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin BA058_19490 ENOG4105DZC cytosine deaminase BA058_19495 ENOG4105DQ6 Transposase BA058_19500 ENOG4105Y25 Transposase BA058_19505 ENOG4108UW5 maltose o-acetyltransferase BA058_19510 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BA058_19515 ENOG4105CNT hydrolase family 2 BA058_19520 ENOG4105ETE Transcriptional regulator (LacI family BA058_19525 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BA058_19530 ENOG4105C4W S-formylglutathione hydrolase BA058_19545 ENOG4105SRB Uncharacterized protein yaiO BA058_19555 ENOG4108PBI Polysaccharide metabolism BA058_19560 ENOG4107W19 lmbE family BA058_19565 ENOG4106FTQ Taurine ABC transporter, periplasmic BA058_19570 ENOG4108IY8 ABC, transporter BA058_19575 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BA058_19580 ENOG4105E2B Taurine dioxygenase BA058_19585 ENOG4105D52 delta-aminolevulinic acid dehydratase BA058_19595 ENOG4108PNB DNA-binding transcriptional regulator BA058_19600 ENOG4107R6D beta-lactam binding protein AmpH BA058_19610 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 BA058_19615 ENOG4107QS8 (LipO)protein BA058_19620 ENOG4105FR5 inner membrane protein YaiY BA058_19625 ENOG4105UNH Membrane BA058_19630 ENOG4105CPF Cell wall formation (By similarity) BA058_19640 ENOG4105G6Z alkaline phosphatase BA058_19645 ENOG4105VIF phosphate starvation-inducible protein BA058_19650 ENOG4105BZU Histidine kinase BA058_19655 ENOG4105II7 pyrroline-5-carboxylate reductase BA058_19670 ENOG4105SS3 BA058_19680 ENOG4105HBA AroM protein BA058_19700 ENOG4105DKQ ROK family BA058_19705 ENOG4105F27 Major Facilitator BA058_19710 ENOG4105EYH Exonuclease BA058_19715 ENOG4107RH8 nuclease SbcCD subunit D BA058_19720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA058_19725 ENOG4105BZU Histidine kinase BA058_19730 ENOG4105CWM branched-chain amino acid transport system II carrier protein BA058_19735 ENOG4105C85 amino acid BA058_19740 ENOG4107R28 alpha amylase, catalytic region BA058_19745 ENOG4108ZYK Acyl carrier protein phosphodiesterase BA058_19750 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BA058_19760 ENOG4105VIE preprotein translocase, subunit YajC BA058_19765 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BA058_19770 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BA058_19775 ENOG4105N1F Hnh endonuclease BA058_19780 ENOG4105DRB nucleoside-specific channel-forming protein BA058_19785 ENOG4108KIC (LipO)protein BA058_19795 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BA058_19800 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BA058_19810 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BA058_19815 ENOG4108ZAI phosphatidylglycerophosphatase a BA058_19820 ENOG4105CPC Aldo Keto reductase BA058_19825 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BA058_19830 ENOG4105CTB Polyprenyl synthetase BA058_19835 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BA058_19845 ENOG4107S0N DJ-1 family BA058_19850 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BA058_19860 ENOG4107RDB Major Facilitator BA058_19870 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BA058_19875 ENOG4105CCU oxidase (Subunit III) BA058_19880 ENOG4105BZ9 Cytochrome C oxidase, subunit I BA058_19885 ENOG4105E2S oxidase) subunit II BA058_19890 ENOG4105EYM Major Facilitator superfamily BA058_19895 ENOG4105IEY (LipO)protein BA058_19900 ENOG4105M85 Bola protein BA058_19910 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BA058_19925 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BA058_19930 ENOG4105K70 DNA-binding protein BA058_19935 ENOG4105EIN peptidylprolyl cis-trans isomerase BA058_19940 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BA058_19945 ENOG4108TGP Thioesterase superfamily protein BA058_19955 ENOG4108NFA extracellular solute-binding protein BA058_19965 ENOG4108XM1 transcriptional regulator AsnC family BA058_19970 ENOG4105BZ1 (ABC) transporter BA058_19975 ENOG4105BZ1 (ABC) transporter BA058_19980 ENOG4108YZA Nitrogen regulatory protein pii BA058_19985 ENOG4105BZU Histidine kinase BA058_19990 ENOG4105C29 acyl-CoA thioesterase BA058_19995 ENOG4108MNP Glycoprotein polysaccharide metabolism BA058_20000 ENOG41080UX Methyltransferase BA058_20010 ENOG4105KCV RNA signal recognition particle 4.5S RNA BA058_20015 ENOG41066DG (EAL) domain protein BA058_20020 ENOG4105GSJ Inner membrane protein ylaC BA058_20025 ENOG4108UW5 maltose o-acetyltransferase BA058_20030 ENOG4105KF5 hemolysin expression-modulating protein BA058_20035 ENOG4108UKR Biofilm formation regulator YbaJ BA058_20040 ENOG4105BZS acriflavin resistance protein BA058_20045 ENOG4105C1P efflux transporter, rnd family, mfp subunit BA058_20050 ENOG4108IG5 Transcriptional regulator BA058_20055 ENOG4105EGS Mechanosensitive ion channel BA058_20065 ENOG4106428 Protein of unknown function (DUF2496) BA058_20070 ENOG4108URS primosomal replication protein n'' BA058_20075 ENOG4105WD1 Membrane BA058_20085 ENOG4107QMP dna polymerase iii subunits gamma and tau BA058_20100 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BA058_20115 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BA058_20120 ENOG4107RE1 Inosine-guanosine kinase BA058_20125 ENOG4105CKD glutathione-regulated potassium-efflux system protein BA058_20130 ENOG4105EU0 Major facilitator Superfamily BA058_20135 ENOG4105CGH 5'-nucleotidase BA058_20150 ENOG4108Z66 YbaK ebsC protein BA058_20155 ENOG4105MBR gumn family BA058_20160 ENOG41080ET plasmid maintenance system killer protein BA058_20165 ENOG41081XE plasmid maintenance system antidote protein, xre family BA058_20170 ENOG4105C59 p-type ATPase BA058_20175 ENOG4105CSV Glutaminase BA058_20180 ENOG4107RY6 amino acid BA058_20185 ENOG4108Z6Z Transcriptional regulator BA058_20195 ENOG4105G5H Membrane BA058_20200 ENOG4107QX8 SPFH domain, Band 7 family protein BA058_20205 ENOG41083J0 (ABC) transporter BA058_20210 ENOG4105C4B ABC transporter, permease BA058_20215 ENOG4107QR8 Thioredoxin BA058_20220 ENOG4105E1F short-chain dehydrogenase reductase BA058_20225 ENOG4108UJV acyl-CoA thioesterase i BA058_20230 ENOG4108I0Y (ABC) transporter BA058_20235 ENOG4105CV6 ABC transporter, permease BA058_20240 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) BA058_20245 ENOG4107653 Transcriptional regulator BA058_20255 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region BA058_20260 ENOG41060W2 glyoxylate carboligase BA058_20265 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BA058_20270 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA058_20275 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BA058_20285 ENOG4105DTE Xanthine uracil vitamin C permease BA058_20290 ENOG4105BZW Glycerate kinase BA058_20295 ENOG4105S0E allantoin catabolism protein BA058_20300 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BA058_20305 ENOG4105DG4 malate L-lactate dehydrogenase BA058_20310 ENOG4107R1Q Membrane protein FdrA BA058_20315 ENOG4107REC cytoplasmic protein BA058_20320 ENOG4105G5A Protein of unknown function (DUF2877) BA058_20325 ENOG4105C5B carbamate kinase BA058_20330 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BA058_20335 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BA058_20345 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) BA058_20350 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BA058_20360 ENOG4105S2T inner membrane protein YbcI BA058_20365 ENOG4105WQ3 Rna-binding protein BA058_20385 ENOG4108KU3 Integrase BA058_20390 ENOG4108KU3 Integrase BA058_20400 ENOG4108WF3 methyltransferase BA058_20405 ENOG4108NC2 Outer membrane protease BA058_20410 ENOG4105QUW BA058_20415 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit BA058_20420 ENOG410802X bacteriophage n4 adsorption protein b BA058_20425 ENOG4105GR3 Histidine kinase BA058_20430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA058_20435 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BA058_20440 ENOG410624V efflux system protein BA058_20445 ENOG4105EP1 Efflux transporter rnd family, mfp subunit BA058_20450 ENOG4108IJF Heavy metal efflux pump, CzcA BA058_20455 ENOG4105C85 amino acid BA058_20460 ENOG4105CUY Mechanosensitive ion channel BA058_20465 ENOG4108RCM Nitroreductase BA058_20470 ENOG4105MSB protein, conserved in bacteria BA058_20475 ENOG4105WQ6 Membrane BA058_20490 ENOG4107635 Hok Gef family protein BA058_20495 ENOG4108TSE Transferase BA058_20500 ENOG4107RNH Outer membrane receptor FepA BA058_20505 ENOG4105E93 esterase BA058_20510 ENOG41085A6 mbth domain-containing protein BA058_20515 ENOG4105C0W non-ribosomal peptide synthetase BA058_20520 ENOG4108QY5 Ferric enterobactin transport protein BA058_20525 ENOG4105E0A ABC, transporter BA058_20530 ENOG4105TVJ transport system, permease BA058_20535 ENOG4105DQ5 transport system permease protein BA058_20540 ENOG4105E8G Major facilitator Superfamily BA058_20545 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BA058_20550 ENOG4105E4F Isochorismate synthase BA058_20555 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BA058_20560 ENOG4105WQI isochorismatase BA058_20565 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BA058_20570 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) BA058_20575 ENOG4105D22 carbon starvation protein BA058_20580 ENOG4105VCD cytoplasmic protein BA058_20585 ENOG4107SCQ Iron-containing alcohol dehydrogenase BA058_20590 ENOG4105CHM Aminotransferase BA058_20595 ENOG4105GTN ParB Domain Protein Nuclease BA058_20600 ENOG4105BZV Phosphoadenosine phosphosulfate reductase BA058_20605 ENOG4105DQS Transcriptional regulator BA058_20610 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase BA058_20615 ENOG4105D3R alkyl hydroperoxide reductase BA058_20620 ENOG4108JU3 Alkyl hydroperoxide reductase BA058_20625 ENOG4108U51 Universal stress protein BA058_20630 ENOG4105NXH GreA GreB family elongation factor BA058_20635 ENOG4105KTS ribonuclease BA058_20640 ENOG4107QPK )-transporter BA058_20645 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase BA058_20655 ENOG4105CHY citrate lyase, alpha BA058_20660 ENOG4105CI0 Citrate lyase BA058_20670 ENOG4105DUA (citrate (pro-3S)-lyase ligase BA058_20675 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BA058_20680 ENOG4106YYS transcriptional regulatory protein BA058_20685 ENOG4105CEE C4-dicarboxylate transporter BA058_20690 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) BA058_20695 ENOG4105VEQ Cold shock protein BA058_20705 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BA058_20710 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BA058_20720 ENOG41064T2 transcriptional regulator, lysR family BA058_20740 ENOG4105DZ1 carboxypeptidase BA058_20745 ENOG4105K6T rare lipoprotein A BA058_20750 ENOG4105CNI cell division protein FtsW BA058_20755 ENOG4105CJN penicillin-binding protein BA058_20765 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BA058_20770 ENOG4108TGR phosphatase BA058_20780 ENOG4105DJF DNA polymerase III, delta' subunit BA058_20795 ENOG4107PAI alpha helical protein BA058_20805 ENOG4105CDA abc transporter atp-binding protein BA058_20810 ENOG4105DRP amino acid AbC transporter BA058_20815 ENOG4105EAD ABC transporter BA058_20820 ENOG4107RP9 extracellular solute-binding protein, family 3 BA058_20825 ENOG4107U91 Rhomboid family BA058_20830 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BA058_20835 ENOG4108JU5 Magnesium and cobalt efflux protein BA058_20845 ENOG4105C9A Phoh family BA058_20855 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BA058_20895 ENOG4105CAQ asparagine synthetase BA058_20900 ENOG4105D4U had-superfamily hydrolase, subfamily iia BA058_20905 ENOG4105E2R ROK family BA058_20910 ENOG4105CE4 GlcNAc 6-P deacetylase BA058_20920 ENOG4105CI1 PTS System BA058_20940 ENOG4105EE5 Membrane protein terC BA058_20945 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA058_20950 ENOG4108JB8 alcohol dehydrogenase BA058_20955 ENOG4107S2N Type III effector Hrp-dependent BA058_20960 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BA058_20965 ENOG4105MVE transcriptional regulator BA058_20980 ENOG4105GX6 (LipO)protein BA058_20985 ENOG41090R7 Ferric uptake BA058_21000 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BA058_21005 ENOG4105NNH LexA regulated protein BA058_21010 ENOG4105EV9 Alpha Beta Hydrolase BA058_21015 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) BA058_21020 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BA058_21025 ENOG4105D5Q Arginine ornithine antiporter BA058_21030 ENOG4105CXN decarboxylase BA058_21040 ENOG4105EEX Two component transcriptional regulator (Winged helix family BA058_21045 ENOG4105C08 Histidine kinase BA058_21050 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) BA058_21070 ENOG4105XIQ Protein of unknown function (DUF2517) BA058_21075 ENOG4107SEY Conserved Protein BA058_21080 ENOG4105CVP deoxyribo-dipyrimidine photolyase BA058_21085 ENOG4105DUX Transporter BA058_21090 ENOG4107QNR UPF0135 protein BA058_21095 ENOG4105P4J Allophanate hydrolase, subunit 1 BA058_21100 ENOG4107R7A Allophanate hydrolase subunit 2 BA058_21110 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) BA058_21115 ENOG4108KK1 membrane protein AbrB duplication BA058_21120 ENOG4108MY7 Fimbrial BA058_21125 ENOG4105BZN citrate synthase BA058_21135 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BA058_21140 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BA058_21145 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BA058_21150 ENOG4105E33 succinate dehydrogenase BA058_21160 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BA058_21165 ENOG4105C7S Dehydrogenase BA058_21175 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BA058_21190 ENOG4105C4M (Ubiquinol oxidase) subunit I BA058_21195 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA058_21205 ENOG4105KJB cyd operon protein YbgE BA058_21210 ENOG4107YD3 Thioesterase BA058_21215 ENOG4105E02 MotA TolQ exbB proton channel BA058_21220 ENOG4105M8F Biopolymer transport protein exbD tolR BA058_21225 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BA058_21235 ENOG4105KCK Peptidoglycan-associated lipoprotein BA058_21240 ENOG4105UFD tol-pal system protein YbgF BA058_21285 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BA058_21290 ENOG4105PGM cation diffusion facilitator family transporter BA058_21295 ENOG4105JND homeobox protein BA058_21305 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BA058_21315 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BA058_21325 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BA058_21330 ENOG4105CMR udp-glucose 4-epimerase BA058_21335 ENOG4105DKW ABC transporter BA058_21345 ENOG4105F4R Transcriptional regulator mode BA058_21350 ENOG410680R Protein of unknown function (DUF2592) BA058_21355 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BA058_21360 ENOG4105E0C molybdate abc transporter BA058_21365 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BA058_21370 ENOG4108K4B hydrolase BA058_21375 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BA058_21380 ENOG4105F04 LysR family Transcriptional regulator BA058_21385 ENOG4105C7F AcnD-accessory protein PrpF BA058_21390 ENOG4107QPK )-transporter BA058_21395 ENOG4107QM5 aconitate hydratase BA058_21400 ENOG4105NBR Pectinesterase BA058_21405 ENOG4108V1U phospholipid-binding protein BA058_21410 ENOG4105D7V transposase BA058_21415 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA058_21420 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BA058_21430 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA058_21435 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BA058_21445 ENOG4105CHW UPF0052 protein BA058_21455 ENOG4108RIR Molybdenum cofactor biosynthesis protein BA058_21465 ENOG4105M00 molybdopterin converting factor, subunit 1 BA058_21470 ENOG4108ZAF Molybdopterin BA058_21475 ENOG4105HFZ Membrane BA058_21480 ENOG410733J conserved inner membrane protein BA058_21485 ENOG4107UXM Membrane BA058_21490 ENOG4105DZQ phospholipase D Transphosphatidylase BA058_21495 ENOG4105X23 Endonuclease Exonuclease phosphatase BA058_21500 ENOG4105I9U inner membrane protein ybhQ BA058_21505 ENOG4107QWP ABC-2 type transporter BA058_21510 ENOG4107QWP ABC-2 type transporter BA058_21515 ENOG4105CJ1 ABC, transporter BA058_21520 ENOG4105D0S secretion protein (HlyD BA058_21525 ENOG4107MVR Transcriptional regulator BA058_21530 ENOG4105C1J atp-dependent rna helicase BA058_21540 ENOG4105DVT helicase BA058_21545 ENOG4108MTB glycosyl transferase family BA058_21550 ENOG4105DG4 malate L-lactate dehydrogenase BA058_21555 ENOG4105VR4 UPF0379 protein ybiJ BA058_21560 ENOG4105KSC Transcriptional regulator, TraR DksA family BA058_21565 ENOG4107E2E PKHD-type hydroxylase BA058_21575 ENOG4105ZY9 UPF0379 protein ybiM BA058_21585 ENOG4105D8X mechanosensitive ion channel BA058_21590 ENOG4105CDA abc transporter atp-binding protein BA058_21595 ENOG4105E5Q amino acid AbC transporter BA058_21600 ENOG4107R0W ABC transporter BA058_21615 ENOG4107AQZ Membrane BA058_21620 ENOG4108T1M outer membrane protein x BA058_21625 ENOG4108I6E Sulfatase BA058_21635 ENOG4105KST dependent repressor BA058_21640 ENOG4105F4P )-transporter BA058_21645 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA058_21650 ENOG4105C5H ABC transporter BA058_21655 ENOG4108HCJ Hydrolase BA058_21660 ENOG4105C6N Formate acetyltransferase BA058_21665 ENOG4105F1A Pyruvate formate-lyase BA058_21670 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA058_21675 ENOG4105D06 uba thif-type nad fad binding protein BA058_21680 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA058_21685 ENOG4105D44 asparaginase BA058_21690 ENOG4108JQ6 ABC transporter BA058_21705 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA058_21710 ENOG4105BZU Histidine kinase BA058_21715 ENOG41064RH membrane protein YliF BA058_21725 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway BA058_21730 ENOG4105D8V Glucose sorbosone dehydrogenase BA058_21735 ENOG4108TGY Glutathione S-transferase BA058_21740 ENOG4105DZ1 carboxypeptidase BA058_21745 ENOG4107FB0 transcriptional regulator DeoR family BA058_21750 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BA058_21755 ENOG4107QF7 multi-drug BA058_21765 ENOG4108HCJ Hydrolase BA058_21770 ENOG4106UW1 Major Facilitator superfamily BA058_21775 ENOG4108RFG Tetr family transcriptional regulator BA058_21785 ENOG4105GWF inner membrane protein YbjM BA058_21790 ENOG41090BQ Glutaredoxin BA058_21795 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BA058_21800 ENOG4108DBC nitroreductase BA058_21810 ENOG4108RMJ sensory transduction regulator BA058_21820 ENOG4107RUE extracellular solute-binding protein family 1 BA058_21825 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA058_21830 ENOG4105F38 ABC transporter, permease BA058_21835 ENOG4105D38 putrescine abc transporter BA058_21840 ENOG4105RBQ inner membrane protein ybjO BA058_21850 ENOG4106TNF Periplasmic binding protein BA058_21855 ENOG4105DMR ABC, transporter BA058_21860 ENOG4105GBT ABC transporter BA058_21865 ENOG4106PMH Extracellular solute-binding protein family 3 BA058_21870 ENOG4105E5Z arginine transporter ATP-binding subunit BA058_21875 ENOG41064MM (LipO)protein BA058_21885 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BA058_21890 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BA058_21895 ENOG4105CGD Nad-dependent epimerase dehydratase BA058_21900 ENOG4105C5W Aldolase BA058_21905 ENOG4105C7K acetolactate synthase BA058_21910 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BA058_21915 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BA058_21920 ENOG4105DWU Membrane BA058_21925 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BA058_21935 ENOG4105CPB ATP-dependent endonuclease of the OLD family BA058_21940 ENOG4108MJ5 VirK protein BA058_21945 ENOG4105DJY efflux transporter, rnd family, mfp subunit BA058_21950 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BA058_21955 ENOG4105VEQ Cold shock protein BA058_22015 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BA058_22035 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BA058_22045 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BA058_22055 ENOG4108JJ8 (ABC) transporter BA058_22060 ENOG4108JJ9 ABC, transporter BA058_22065 ENOG4105C3M thioredoxin reductase BA058_22070 ENOG4105EW9 transcriptional regulator AsnC family BA058_22075 ENOG4105CNU cell division protein FtsK BA058_22085 ENOG4105D1H recombination factor protein RarA BA058_22095 ENOG4107QY8 reductase BA058_22100 ENOG4105QAX Iron-sulfur BA058_22105 ENOG4107KGK dmso reductase anchor subunit BA058_22110 ENOG4105CHJ isochorismatase hydrolase BA058_22115 ENOG4108ISG Major Facilitator BA058_22120 ENOG4105F1A Pyruvate formate-lyase BA058_22125 ENOG4105C6N Formate acetyltransferase BA058_22130 ENOG4105TMB Formate nitrite transporter BA058_22135 ENOG4105DDY UPF0142 protein ycaO BA058_22140 ENOG4107VMU Membrane BA058_22155 ENOG4108K0D peptidase, M48 BA058_22165 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BA058_22175 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BA058_22180 ENOG4105BZ1 (ABC) transporter BA058_22185 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) BA058_22190 ENOG4105T0Z Conserved Protein BA058_22205 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BA058_22210 ENOG4107S90 membrAne BA058_22215 ENOG4106371 Methyltransferase BA058_22225 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BA058_22230 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) BA058_22235 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BA058_22240 ENOG4105EAQ (twin-arginine translocation) pathway signal BA058_22245 ENOG4105C5X domain protein BA058_22250 ENOG4105CGF Aromatic amino acid aminotransferase BA058_22275 ENOG4105CD8 aminopeptidase N BA058_22280 ENOG4105E2Y ABC, transporter BA058_22285 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BA058_22290 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BA058_22295 ENOG4105GVF (ABC) transporter BA058_22300 ENOG4108UZX fmn reductase BA058_22310 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BA058_22315 ENOG4105QVC MOSC domain-containing protein BA058_22320 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BA058_22325 ENOG4105C5H ABC transporter BA058_22330 ENOG4105F1S paraquat-inducible protein a BA058_22335 ENOG4105DY2 Paraquat-inducible protein b BA058_22340 ENOG4108Q2G (LipO)protein BA058_22345 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) BA058_22355 ENOG4105DAN ATP-dependent protease BA058_22360 ENOG4108R9Q Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity) BA058_22365 ENOG4105UYK outer membrane protein a BA058_22380 ENOG4108RZ1 DNA transformation protein BA058_22385 ENOG4105EM2 membrane BA058_22390 ENOG410901E Membrane BA058_22395 ENOG41088T4 Helicase IV BA058_22415 ENOG4105K4P CoA-binding domain protein BA058_22430 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 BA058_22435 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BA058_22440 ENOG4108MN8 Membrane BA058_22450 ENOG4105E3S small subunit BA058_22455 ENOG4105DPX Hydrogenase, large subunit BA058_22460 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit BA058_22465 ENOG4108USZ hydrogenase BA058_22470 ENOG4108VXY Hydrogenase-1 operon protein HyaE BA058_22475 ENOG4105MVP hydrogenase-1 operon protein HyaF BA058_22480 ENOG4105C4M (Ubiquinol oxidase) subunit I BA058_22485 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA058_22495 ENOG4105D6F Phosphatase BA058_22500 ENOG41060EU Cold shock-like protein BA058_22505 ENOG4105VEQ Cold shock protein BA058_22515 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation BA058_22520 ENOG4105HEE Binding Domain protein BA058_22525 ENOG4105BZU Histidine kinase BA058_22530 ENOG4108SV3 Tmao reductase system periplasmic protein tort BA058_22535 ENOG4106WF9 DNA-binding transcriptional regulator TorR BA058_22540 ENOG4105CUW cytochrome C-TYPE protein BA058_22545 ENOG4108EM1 reductase BA058_22565 ENOG4105D6F Phosphatase BA058_22570 ENOG4105XH3 BA058_22585 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 BA058_22590 ENOG4105C2W permease BA058_22595 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) BA058_22605 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BA058_22615 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BA058_22620 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) BA058_22625 ENOG4108R86 Transcriptional regulator BA058_22630 ENOG4105C26 Dehydrogenase BA058_22640 ENOG4105CK7 Sodium proline symporter BA058_22645 ENOG4105EKT )-iron permease BA058_22655 ENOG4105DBE peroxidase BA058_22660 ENOG4105D5M phosphate starvation-inducible protein BA058_22665 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BA058_22670 ENOG4105CND Glycosyl transferase, family 2 BA058_22675 ENOG4107BJW polysaccharide deacetylase BA058_22680 ENOG4108TUY outer membrane protein PgaA BA058_22685 ENOG4105BZU Histidine kinase BA058_22700 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase BA058_22710 ENOG4107XHZ cytoplasmic chaperone TorD family protein BA058_22715 ENOG4108UQ5 membrane protein YcdZ BA058_22720 ENOG4105P8Q Curli production assembly transport component CsgG BA058_22725 ENOG4108WYR Curli production assembly transport component, CsgF BA058_22730 ENOG4108XDW curli assembly protein CsgE BA058_22735 ENOG41086KC Transcriptional regulator BA058_22745 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers BA058_22750 ENOG41090QH cryptic curlin major subunit BA058_22765 ENOG4108UVJ appr-1-p processing domain protein BA058_22770 ENOG4107RZC phospholipase d BA058_22775 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BA058_22795 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BA058_22800 ENOG4105NAC (LipO)protein BA058_22805 ENOG4108W47 Acidic protein msyB BA058_22815 ENOG4105C6X Major Facilitator BA058_22820 ENOG4105D1S lipid A biosynthesis BA058_22825 ENOG4105C72 UPF0176 protein BA058_22830 ENOG4108YYC ycei family BA058_22835 ENOG4105DS1 cytochrome b561 BA058_22840 ENOG4106974 biofilm formation BA058_22850 ENOG4105PVA Biofilm formation regulatory protein BssS BA058_22855 ENOG4105MEA DNA damage-inducible protein i BA058_22860 ENOG4105EKE dihydroorotase BA058_22865 ENOG4105F3T (LipO)protein BA058_22870 ENOG4105E9S glutaredoxin 2 BA058_22880 ENOG4105D9U N-acetyltransferase BA058_22890 ENOG4105EP9 oxidoreductase BA058_22895 ENOG4105CJR Integral membrane protein (MviN BA058_22900 ENOG4105QVD Flagella synthesis protein FlgN BA058_22905 ENOG4105M9M anti-sigma28 factor FlgM BA058_22910 ENOG4105CKS Flagella basal body P-ring formation protein flgA BA058_22915 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BA058_22920 ENOG4108ZC9 flagellar basal-body rod protein flgc BA058_22925 ENOG4105W00 Flagellar hook capping protein BA058_22930 ENOG4105BZE flagellar hook protein, FlgE BA058_22935 ENOG4108KPB Flagellar basal-body rod protein FlgF BA058_22940 ENOG4105CGA flagellar basal-body rod protein FlgG BA058_22955 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BA058_22960 ENOG4105E1Q flagellar hook-associated protein BA058_22965 ENOG4105DTJ flagellar hook-associated protein BA058_22970 ENOG4107QQB Ribonuclease E BA058_22975 ENOG41071G1 Uncharacterized protein YceQ BA058_22980 ENOG4105EI2 Pseudouridine synthase BA058_22985 ENOG4108UHJ MAF-like protein BA058_22990 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BA058_23010 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BA058_23015 ENOG4105CHR reductase BA058_23020 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BA058_23025 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA058_23030 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BA058_23035 ENOG4105HHA aminodeoxychorismate lyase BA058_23045 ENOG4107QRG dna polymerase iii BA058_23050 ENOG4105F8V Hydrolase, tatD family BA058_23055 ENOG4105CI1 PTS System BA058_23065 ENOG4105K59 histidine triad (HIT) protein BA058_23070 ENOG41090DQ Lipoprotein BA058_23075 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) BA058_23080 ENOG4108RUM thiamine kinase BA058_23095 ENOG4105CEP NADH dehydrogenase BA058_23100 ENOG4107MBR 17 kDa surface antigen BA058_23105 ENOG4108IND Tetr family transcriptional regulator BA058_23110 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BA058_23115 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA058_23120 ENOG4108JA2 transcriptioN-repair coupling factor BA058_23130 ENOG4105D60 lipoprotein releasing system transmembrane protein BA058_23135 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BA058_23140 ENOG4105D60 lipoprotein releasing system transmembrane protein BA058_23150 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BA058_23165 ENOG4107RUE extracellular solute-binding protein family 1 BA058_23170 ENOG4105D38 putrescine abc transporter BA058_23175 ENOG4105F38 ABC transporter, permease BA058_23180 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA058_23195 ENOG4105EZE Cupin 4 family protein BA058_23200 ENOG4105IFJ Histidine kinase BA058_23205 ENOG4105XJC Two component transcriptional regulator (Winged helix family BA058_23210 ENOG4107QTF adenylosuccinate lyase BA058_23235 ENOG4108HMX isocitrate dehydrogenase (NADP) BA058_23240 ENOG4108I1J Integrase BA058_23345 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi BA058_23350 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 BA058_23355 ENOG4105RWQ Protein of unknown function (DUF1364) BA058_23370 ENOG4105HRS Antitermination protein BA058_23380 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BA058_23385 ENOG4105KUS lysozyme BA058_23390 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BA058_23395 ENOG4105QYK bacteriophage lambda Bor protein homolog BA058_23425 ENOG4105UZW Tail fiber assembly protein BA058_23450 ENOG4105IM0 capsid protein BA058_23535 ENOG410685N tail fiber protein BA058_23540 ENOG4105UZW Tail fiber assembly protein BA058_23545 ENOG4105CC5 ABC transporter BA058_23550 ENOG4105CC5 ABC transporter BA058_23555 ENOG4105DIK (ABC) transporter BA058_23570 ENOG41064WM Uncharacterized protein YcgX BA058_23575 ENOG4108XDN Transcriptional regulator BA058_23580 ENOG4105BZU Histidine kinase BA058_23585 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component BA058_23590 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB BA058_23600 ENOG410738I uncharacterized protein ymgC BA058_23605 ENOG4105BZU Histidine kinase BA058_23630 ENOG410658X BA058_23655 ENOG4107QMS site-determining protein BA058_23660 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BA058_23665 ENOG4105S66 prophage protein BA058_23670 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium BA058_23680 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BA058_23685 ENOG4108ZZ3 UPF0260 protein BA058_23690 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells BA058_23695 ENOG4105KT5 UmuD protein BA058_23700 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BA058_23705 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) BA058_23710 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BA058_23720 ENOG4105ED1 spovr family BA058_23730 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA058_23740 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BA058_23750 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) BA058_23765 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BA058_23770 ENOG4108BSC Methyltransferase BA058_23775 ENOG4105E0A ABC, transporter BA058_23780 ENOG4105EHG Permease protein BA058_23785 ENOG4105S10 periplasmic binding protein BA058_23790 ENOG4105E53 ec 3.2.1.28 BA058_23795 ENOG4105VDH Dihydroxyacetone kinase BA058_23800 ENOG4108UTZ Dihydroxyacetone kinase BA058_23805 ENOG4105CMT Dihydroxyacetone kinase BA058_23810 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BA058_23820 ENOG4105C3G gtp-binding protein BA058_23830 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BA058_23835 ENOG4105CHH sulfate transporter BA058_23840 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BA058_23850 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) BA058_23865 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BA058_23870 ENOG4108YY7 Invasion gene expression up-regulator SirB BA058_23875 ENOG41063JG Transcriptional regulator BA058_23890 ENOG4105EWV Sodium calcium exchanger membrane region BA058_23895 ENOG4105WS7 Cation transport regulator BA058_23900 ENOG4108NH8 Cation transport protein BA058_23905 ENOG41090EX DsrE family BA058_23910 ENOG4105ID0 Putative invasin BA058_23915 ENOG4105WH1 Two component transcriptional regulator luxr family BA058_23920 ENOG4105BZU Histidine kinase BA058_23930 ENOG4105DQQ Major facilitator superfamily MFS_1 BA058_23935 ENOG4105CRU nitrate reductase, alpha subunit BA058_23940 ENOG4108IUE nitrate reductase beta subunit BA058_23945 ENOG4105R3A Nitrate reductase BA058_23950 ENOG41076YT nitrate reductase, gamma subunit BA058_23975 ENOG4105CIY formyltetrahydrofolate deformylase BA058_23980 ENOG4105K5B UPF0225 protein BA058_23985 ENOG4105D78 K07001 NTE family protein BA058_23990 ENOG4105I93 response regulator BA058_23995 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA058_24000 ENOG4108SAU DNA-binding protein H-ns BA058_24005 ENOG4107104 thymidine kinase BA058_24015 ENOG4108EKI Dehydrogenase BA058_24020 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BA058_24030 ENOG4108J59 Extracellular solute-binding protein, family 5 BA058_24040 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA058_24045 ENOG4105C3U ABC transporter BA058_24050 ENOG4108JQ7 (ABC) transporter BA058_24070 ENOG4107SVH Potassium channel protein BA058_24075 ENOG4105K9H YciI-like protein BA058_24080 ENOG410822N TonB family BA058_24085 ENOG4105NAU thioesterase Superfamily protein BA058_24100 ENOG4105EIF outer membrane protein W BA058_24105 ENOG4108N8X transition metal ion binding BA058_24110 ENOG4108Z9Z response to DNA damage stimulus BA058_24120 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BA058_24130 ENOG4105DK0 Indole-3-glycerol phosphate synthase BA058_24135 ENOG4108EFP Anthranilate synthase component II BA058_24140 ENOG4105CRQ synthase (Component I) BA058_24145 ENOG4105DB7 PHP domain protein BA058_24150 ENOG4107RTD sua5 ycio yrdc ywlc family protein BA058_24155 ENOG4105EG3 transmembrane signal peptide protein BA058_24160 ENOG4105FE9 pseudouridine synthase BA058_24175 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BA058_24180 ENOG4105UBK short-chain dehydrogenase reductase BA058_24190 ENOG4105ERU peptidase BA058_24195 ENOG4105RKX Protein of unknown function (DUF2498) BA058_24205 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BA058_24210 ENOG4107R11 Transcriptional regulator BA058_24230 ENOG4107QM5 aconitate hydratase BA058_24240 ENOG4105EYK Phosphatidylglycerophosphatase B BA058_24245 ENOG4105Q4A inner membrane protein yciS BA058_24250 ENOG4105CFV Tetratricopeptide repeat protein BA058_24255 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BA058_24260 ENOG4108ZJT translation initiation factor, Sui1 BA058_24265 ENOG41061RM osmotically inducible lipoprotein BA058_24270 ENOG4105N2W Transcriptional regulator BA058_24280 ENOG4105BZU Histidine kinase BA058_24290 ENOG4108IEC Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) BA058_24295 ENOG4105Q4T oxidoreductase BA058_24300 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BA058_24305 ENOG41067SE Tetr family transcriptional regulator BA058_24310 ENOG4105C1P efflux transporter, rnd family, mfp subunit BA058_24315 ENOG4105BZS acriflavin resistance protein BA058_24320 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BA058_24325 ENOG4105C2C drug resistance transporter, Bcr CflA BA058_24330 ENOG4108JQ2 peptide transport system atp-binding protein BA058_24335 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BA058_24340 ENOG4108EU3 peptide transport system, permease BA058_24345 ENOG4108I5W peptide transport system, permease protein BA058_24350 ENOG4108HIY periplasmic BA058_24355 ENOG4105N0E Protein of unknown function (DUF2543) BA058_24360 ENOG4108JPW Aminotransferase BA058_24365 ENOG4105E51 psp operon transcriptional activator BA058_24370 ENOG41087YS Phage shock protein A BA058_24375 ENOG4105YYT phage shock protein B BA058_24380 ENOG4105FM1 phage shock protein C BA058_24385 ENOG4105NNG Peripheral inner membrane phage-shock protein BA058_24390 ENOG4105K8Z Phage shock protein BA058_24395 ENOG4107QW3 Sucrose phosphorylase BA058_24400 ENOG4105WEM extracellular solute-binding protein BA058_24405 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component BA058_24410 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BA058_24415 ENOG4107RRD Dehydrogenase BA058_24420 ENOG4107TYA transient receptor potential locus BA058_24425 ENOG4105CK5 oxidoreductase BA058_24435 ENOG4107URF beta-phospho-glucomutase BA058_24445 ENOG4107EFV Outer membrane protein G BA058_24450 ENOG4105FKQ transcriptional regulator BA058_24455 ENOG4105CM6 amino acid regulated cytosolic protein BA058_24465 ENOG4108JU8 Transcriptional regulator BA058_24470 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BA058_24475 ENOG4107S8C mandelate racemase muconate lactonizing BA058_24480 ENOG4105KXI murein peptide amidase A BA058_24490 ENOG4105ENX hydrolase BA058_24495 ENOG4105EQ2 LysR family Transcriptional regulator BA058_24505 ENOG4107QSI ABC, transporter BA058_24510 ENOG4105D64 Mechanosensitive ion channel BA058_24515 ENOG4105S5I Membrane BA058_24520 ENOG4105Q9Y Universal stress protein BA058_24525 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BA058_24530 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA058_24535 ENOG4105CFC Transporter BA058_24545 ENOG4105R1U AraC Family Transcriptional Regulator BA058_24560 ENOG4108DG9 Smr protein MutS2 BA058_24565 ENOG4105BZU Histidine kinase BA058_24570 ENOG4107RX3 Mg2 transporter protein cora family protein BA058_24580 ENOG4105C1J atp-dependent rna helicase BA058_24590 ENOG4107R08 Integrase BA058_24595 ENOG4105CC5 ABC transporter BA058_24605 ENOG4108RW8 Universal stress protein F BA058_24610 ENOG4105FCK Membrane BA058_24615 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BA058_24625 ENOG41090X5 Heat shock protein hslJ BA058_24630 ENOG4105C5I Dehydrogenase BA058_24635 ENOG4107H52 Dicarboxylate transport BA058_24640 ENOG410689M (LipO)protein BA058_24645 ENOG4105WXT Conserved Protein BA058_24650 ENOG4107EF2 surface-exposed virulence protein BA058_24655 ENOG4107S5I aldo keto reductase BA058_24660 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BA058_24665 ENOG4108HPI phosphatidate Cytidylyltransferase BA058_24670 ENOG4105E8V Alpha Beta Hydrolase Fold protein BA058_24680 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BA058_24685 ENOG4105CQ7 ATP-dependent helicase BA058_24690 ENOG4107DB1 DUF218 domain BA058_24695 ENOG4105C26 Dehydrogenase BA058_24700 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BA058_24705 ENOG4105CPW cytochrome b561 BA058_24710 ENOG4105UPP uncharacterized protein ydcA BA058_24715 ENOG4107NK6 Hok/gef family BA058_24720 ENOG4105C8Q Methyl-accepting chemotaxis BA058_24725 ENOG4105C8Q Methyl-accepting chemotaxis BA058_24730 ENOG4105DDW LysR family Transcriptional regulator BA058_24750 ENOG4105Z2P Protein of unknown function (DUF465) BA058_24755 ENOG4108Z9I -acetyltransferase BA058_24760 ENOG4107WE3 acetyltransferase YdcK BA058_24765 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein BA058_24770 ENOG41088CC tellurite resistance protein tehB BA058_24775 ENOG4108KKZ (LipO)protein BA058_24780 ENOG4105DKK Benzoate BA058_24785 ENOG4108JCI Transcriptional regulator BA058_24790 ENOG4105CFP Peptidase U32 BA058_24795 ENOG4105RR0 Protein of unknown function (DUF2554) BA058_24805 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA058_24810 ENOG4107TYH extracellular solute-binding protein family 1 BA058_24815 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA058_24820 ENOG4105D81 ABC transporter, permease BA058_24825 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BA058_24840 ENOG410654E Membrane BA058_24845 ENOG4105R71 cytoplasmic protein BA058_24850 ENOG4108T9Y Inner membrane protein ydcZ BA058_24855 ENOG4108Z7F N-acetyltransferase BA058_24860 ENOG4108WYP Transcriptional regulator BA058_24865 ENOG4105CHB tonB-dependent Receptor BA058_24870 ENOG4108NS2 receptor BA058_24875 ENOG4105C85 amino acid BA058_24880 ENOG4108N27 Glutathione S-transferase BA058_24885 ENOG4108N27 Glutathione S-transferase BA058_24895 ENOG4105CS6 Rhs element vgr protein BA058_24910 ENOG410600T transposase BA058_24925 ENOG4108MEJ flavin reductase domain protein BA058_24930 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BA058_24935 ENOG4105JAB phenazine biosynthesis protein, phzf family BA058_24940 ENOG4105D0D Nitrate reductase 2, gamma subunit BA058_24945 ENOG4108NZN Respiratory nitrate reductase 2 delta chain BA058_24950 ENOG4108IUE nitrate reductase beta subunit BA058_24955 ENOG4105CRU nitrate reductase, alpha subunit BA058_24960 ENOG4107QND Nitrite extrusion protein BA058_24965 ENOG4105RPH Inner membrane protein YddG BA058_24970 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_24975 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BA058_24980 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BA058_24985 ENOG4108MG3 formate dehydrogenase BA058_24990 ENOG41084S7 Plasmid maintenance system antidote protein BA058_25000 ENOG4105DQ4 alcohol dehydrogenase BA058_25010 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein BA058_25015 ENOG4105TPS biofilm-dependent modulation protein BA058_25020 ENOG4108Z9K Osmotically inducible protein BA058_25025 ENOG4105BZU Histidine kinase BA058_25030 ENOG4105BZU Histidine kinase BA058_25030 ENOG4105BZU Histidine kinase BA058_25035 ENOG4105F32 YngK protein BA058_25040 ENOG4105E5D amino acid BA058_25045 ENOG4105CVK Glutamate decarboxylase BA058_25055 ENOG4107RAN Peptidase, M16 BA058_25060 ENOG4105PE1 Receptor BA058_25065 ENOG4105CQ0 ABC transporter BA058_25070 ENOG4105C4X radical SAM domain protein BA058_25075 ENOG4105ENH Sulfatase BA058_25090 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BA058_25095 ENOG4106PIH fimbrial-like protein ydeQ BA058_25100 ENOG4106318 fimbrial-like protein YdeR BA058_25105 ENOG4108WDE Fimbrial protein BA058_25110 ENOG4105CW0 outer membrane usher protein BA058_25120 ENOG4108RQP Major type 1 subunit fimbrin BA058_25150 ENOG4105GVR general secretion pathway protein D BA058_25150 ENOG4105GVR general secretion pathway protein D BA058_25215 ENOG4105GVR general secretion pathway protein D BA058_25215 ENOG4105GVR general secretion pathway protein D BA058_25280 ENOG4105GVR general secretion pathway protein D BA058_25280 ENOG4105GVR general secretion pathway protein D