locus-tag class description E3160_00005 ENOG4105QTB Flavodoxin E3160_00010 ENOG4108VVK transcriptional Regulator, AsnC E3160_00020 ENOG4105EV2 VWA domain protein interacting with AAA ATPase E3160_00030 ENOG4105DFH Transport of potassium into the cell (By similarity) E3160_00035 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) E3160_00040 ENOG4105C2J ABC transporter E3160_00045 ENOG4105CNN ABC, transporter E3160_00050 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E3160_00055 ENOG4108RVA ribokinase E3160_00060 ENOG4105ETE Transcriptional regulator (LacI family E3160_00065 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3160_00070 ENOG4107EJG GntR family transcriptional regulator E3160_00110 ENOG4108WFC UPF0438 protein yifE E3160_00115 ENOG4105C0P Mg chelatase subunit ChlI E3160_00135 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit E3160_00140 ENOG4105CM2 brancheD-chain amino acid aminotransferase E3160_00150 ENOG4105C7B Threonine dehydratase E3160_00155 ENOG4105EMY transcriptional regulator E3160_00165 ENOG4105KQ5 peptidylprolyl cis-trans isomerase E3160_00175 ENOG4105C4R Atp-dependent dna helicase E3160_00200 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) E3160_00205 ENOG4105ESV Glycosyl transferase, family 4 E3160_00210 ENOG4105SFE lipopolysaccharide biosynthesis protein E3160_00215 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase E3160_00220 ENOG4107QQG Dehydrogenase E3160_00225 ENOG4105C1B dTDP-glucose 4-6-dehydratase E3160_00230 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) E3160_00235 ENOG4108WJ1 acetyltransferase E3160_00240 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E3160_00245 ENOG4105EGZ biosynthesis protein E3160_00265 ENOG4105C85 amino acid E3160_00300 ENOG4105C4X radical SAM domain protein E3160_00305 ENOG4105ENH Sulfatase E3160_00310 ENOG410601J HemY protein E3160_00315 ENOG4105ECF c-methyltransferase E3160_00320 ENOG41076E6 Uroporphyrinogen-III Synthase E3160_00330 ENOG4107T0K Adenylate cyclase E3160_00345 ENOG4105S7Z (LipO)protein E3160_00355 ENOG4105CT0 Protein of unknown function, DUF484 E3160_00365 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant E3160_00370 ENOG4105C4R Atp-dependent dna helicase E3160_00375 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase E3160_00380 ENOG4108T58 Mg2 transport protein CorA E3160_00385 ENOG4107QUT magnesium and cobalt transport protein CorA E3160_00400 ENOG4107QUT magnesium and cobalt transport protein CorA E3160_00415 ENOG4105FR1 rard protein E3160_00420 ENOG4108VUY thioesterase Superfamily protein E3160_00425 ENOG4105HDD phospholipase E3160_00430 ENOG4105C9U ATP-dependent DNA helicase RecQ E3160_00435 ENOG4105CCF Lysine exporter protein (Lyse ygga) E3160_00440 ENOG410829K Lysine exporter protein (Lyse ygga) E3160_00445 ENOG4108EUD Lysophospholipase E3160_00450 ENOG4105DQF Hydrolase E3160_00455 ENOG4105EMK carboxylate amino acid amine transporter E3160_00460 ENOG4105DZ2 Transcriptional regulator E3160_00470 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) E3160_00475 ENOG4108I5U Uridine phosphorylase E3160_00480 ENOG4105CGY Dna recombination protein E3160_00490 ENOG4105JC1 sterol-binding domain protein E3160_00500 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) E3160_00505 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) E3160_00510 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) E3160_00515 ENOG4105F8V Hydrolase, tatD family E3160_00520 ENOG4105MDZ Transcriptional activator rfaH E3160_00525 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) E3160_00530 ENOG4108EX3 reductase E3160_00535 ENOG4105CHU acetyl-coa acetyltransferase E3160_00550 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein E3160_00555 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) E3160_00560 ENOG4108RR8 protoporphyrinogen oxidase E3160_00590 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b E3160_00595 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) E3160_00600 ENOG4105PC1 Conserved Protein E3160_00605 ENOG4105E27 serine threonine protein kinase E3160_00610 ENOG4108Z33 Thiol disulfide Interchange Protein E3160_00620 ENOG4106HNH Acyl-transferase E3160_00630 ENOG4105C2M dna polymerase I E3160_00640 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) E3160_00645 ENOG4105D4P Coproporphyrinogen iii oxidase E3160_00650 ENOG4106FIY E3160_00655 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3160_00660 ENOG4105CUX Signal transduction histidine kinase E3160_00665 ENOG4105C5F glutamine synthetase E3160_00670 ENOG4105CI3 gtp-binding protein typa E3160_00675 ENOG4108K85 Transcriptional regulator E3160_00680 ENOG4108KHF Resistance protein E3160_00685 ENOG4105R9B Major Facilitator E3160_00690 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is E3160_00695 ENOG4105CT4 transporter E3160_00700 ENOG4105CT4 transporter E3160_00705 ENOG4105CJQ hydrolase, family 31 E3160_00715 ENOG4107WI4 Aldose-1-epimerase E3160_00720 ENOG4107QKS N-acylglucosamine 2-epimerase E3160_00725 ENOG4105D2M Aldolase E3160_00730 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3160_00735 ENOG4108MGF sugar kinase E3160_00740 ENOG4105E98 transcriptional regulator DeoR family E3160_00745 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 E3160_00760 ENOG4105SUU thioesterase domain E3160_00790 ENOG41068KX affects formate dehydrogenase-N E3160_00800 ENOG4108MG3 formate dehydrogenase E3160_00805 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3160_00820 ENOG4108V87 frv operon regulatory protein E3160_00825 ENOG4106C3V frv operon regulatory protein E3160_00830 ENOG4105CN9 Peptidase m42 family protein E3160_00835 ENOG4105DM4 PTS System E3160_00840 ENOG41064BA PTS system, fructose-specific, IIA component E3160_00880 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) E3160_00890 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3160_00900 ENOG4108RPX mosc domain containing protein E3160_00905 ENOG4105E0F Histidine kinase E3160_00910 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3160_00915 ENOG4105FMW periplasmic E3160_00930 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein E3160_00945 ENOG4105EBK exported protein E3160_00950 ENOG4108VTS Membrane E3160_00955 ENOG41065TG regulatoR E3160_00965 ENOG4105DP0 ferredoxin-NADP reductase E3160_00970 ENOG4105CBT Fructose-1,6-bisphosphatase E3160_00980 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E3160_01005 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase E3160_01020 ENOG41063M6 Cell Division Protein E3160_01025 ENOG4105ETE Transcriptional regulator (LacI family E3160_01030 ENOG4105C25 Primosomal protein n' E3160_01040 ENOG4105CNA YD repeat protein E3160_01055 ENOG4107S01 Repressor protein MetJ E3160_01065 ENOG4105C28 cystathionine E3160_01070 ENOG4105CFH Aspartokinase E3160_01075 ENOG4105SYT Methylenetetrahydrofolate reductase E3160_01085 ENOG4108Q5Y Membrane E3160_01090 ENOG4108XC3 NADH ubiquinone oxidoreductase E3160_01095 ENOG4105DCT glycerol dehydrogenase E3160_01100 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E3160_01105 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E3160_01110 ENOG4105DM4 PTS System E3160_01115 ENOG4108YRF PTS System E3160_01125 ENOG4108AHH pyruvate formate lyase II activase E3160_01130 ENOG4108XCZ PTS System E3160_01135 ENOG4106R3P AraC family transcriptional regulator E3160_01140 ENOG4105DIJ Phosphoethanolamine transferase E3160_01155 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase E3160_01170 ENOG4105C5Q Transcriptional regulator E3160_01180 ENOG4105CH2 amidohydrolase E3160_01190 ENOG4105EJ2 Transcriptional regulator E3160_01195 ENOG4108Y73 Membrane E3160_01200 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) E3160_01205 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) E3160_01210 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) E3160_01235 ENOG4105D4A Cell wall formation (By similarity) E3160_01240 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase E3160_01275 ENOG4105PM1 preprotein translocase subunit SecE E3160_01280 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) E3160_01315 ENOG410645W Thiamin biosynthesis protein ThiH E3160_01320 ENOG4105D41 biosynthesis protein thiH E3160_01325 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) E3160_01330 ENOG4105WHD thiamine biosynthesis protein ThiS E3160_01335 ENOG4105D06 uba thif-type nad fad binding protein E3160_01370 ENOG4105R2J Conserved Protein E3160_01380 ENOG4108T8B Protein of unknown function (DUF1481) E3160_01385 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism E3160_01390 ENOG4105BZU Histidine kinase E3160_01395 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3160_01400 ENOG4105C12 Phosphoribosylglycinamide synthetase E3160_01430 ENOG4105K5X acetyltransferase E3160_01440 ENOG4107QP3 malate synthase g E3160_01445 ENOG4108I9X Isocitrate lyase E3160_01460 ENOG41069M3 Transcriptional regulator E3160_01465 ENOG4105C3R Methionine synthase E3160_01470 ENOG4105EAM Na Pi-cotransporter E3160_01480 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein E3160_01485 ENOG4105F3R pts system mannose fructose sorbose family iid E3160_01490 ENOG4105ETZ PTS System E3160_01495 ENOG4105KPI PTS system sorbose subfamily IIB component E3160_01500 ENOG4108XCU pts system E3160_01505 ENOG4105CHR reductase E3160_01510 ENOG4105DKT Transcriptional regulator E3160_01515 ENOG4105FE9 pseudouridine synthase E3160_01520 ENOG4108ZR5 Conserved Protein E3160_01525 ENOG4105CFH Aspartokinase E3160_01535 ENOG4107QP8 phosphohexose isomerase E3160_01545 ENOG4108MDC (LipO)protein E3160_01550 ENOG4108Q9C Periplasmic Protein E3160_01555 ENOG4105E3R (LipO)protein E3160_01570 ENOG4107QNK )-transporter E3160_01575 ENOG4105EG2 ABC transporter, permease E3160_01580 ENOG4105D56 permease protein E3160_01585 ENOG4107FKK extracellular solute-binding protein family 1 E3160_01590 ENOG4108IJ9 (ABC) transporter E3160_01600 ENOG4107W52 maltose operon periplasmic protein E3160_01625 ENOG41080IJ Diacylglycerol kinase E3160_01635 ENOG4107R73 Mate efflux family protein E3160_01640 ENOG4105VDW Csbd family E3160_01645 ENOG4105MYN Zinc uptake regulation protein E3160_01655 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E3160_01685 ENOG4105RDA repressor E3160_01690 ENOG41078CG DNA-binding transcriptional regulator E3160_01745 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_01750 ENOG4105KUS lysozyme E3160_01765 ENOG4106YSC E3160_01870 ENOG4108X9F tail fiber protein E3160_01905 ENOG4106FE3 DNA repair E3160_01915 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E3160_01920 ENOG4105P4Z Phage shock protein G E3160_01925 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein E3160_01930 ENOG4105CDU Replicative dna helicase E3160_01935 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E3160_01940 ENOG4105CGF Aromatic amino acid aminotransferase E3160_01950 ENOG4105F0S class B acid phosphatase E3160_01955 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme E3160_01960 ENOG4105MSB protein, conserved in bacteria E3160_01965 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) E3160_01970 ENOG4108UUM single-stranded DNA-binding protein E3160_01975 ENOG4105PMV Membrane E3160_01980 ENOG4108M8H domain protein E3160_01985 ENOG4108W3Q Transcriptional regulator E3160_01990 ENOG4108Z4X TRANSCRIPTIONal E3160_01995 ENOG4105C7N Xanthine uracil vitamin C permease E3160_02000 ENOG4105EEQ Na H antiporter E3160_02015 ENOG41062QD Membrane E3160_02020 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E3160_02030 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit E3160_02035 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3160_02040 ENOG4105DVI reductase, NrfD E3160_02045 ENOG4108QKW cytochrome c-type biogenesis protein E3160_02055 ENOG4108W0S formate-dependent nitrite reductase complex E3160_02060 ENOG4105CK2 sodium dicarboxylate symporter E3160_02065 ENOG41082ND Uncharacterized protein yjcO E3160_02080 ENOG4105ETP RND efflux system, outer membrane lipoprotein E3160_02085 ENOG4108MI0 Resistance protein E3160_02090 ENOG4105J12 Multidrug resistance protein mdtN E3160_02100 ENOG4105EUZ Beta-lactamase domain protein E3160_02115 ENOG4105D2N Aldolase E3160_02125 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E3160_02130 ENOG4105CNN ABC, transporter E3160_02135 ENOG4105C2J ABC transporter E3160_02150 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 E3160_02155 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein E3160_02160 ENOG410849A acetyltransferase, (GNAT) family E3160_02165 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) E3160_02170 ENOG4105FD8 phosphonate metabolism protein PhnM E3160_02175 ENOG4105HRV phosphonate c-p lyase system protein phnl E3160_02180 ENOG4105ENV phosphonate C-P lyase system protein PhnK E3160_02185 ENOG4105FT8 Phosphonate metabolism E3160_02190 ENOG4105EKV Phosphonate metabolism protein E3160_02195 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH E3160_02200 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG E3160_02205 ENOG4107RJJ Transcriptional regulator E3160_02215 ENOG4105EHI Phosphonate ABC transporter, periplasmic E3160_02220 ENOG4105D5T phosphonate abc transporter E3160_02225 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase E3160_02230 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA E3160_02235 ENOG4108F5E vimentin E3160_02240 ENOG4108YIV E3160_02245 ENOG4105CSH Transporter E3160_02255 ENOG4105ECM Sensor protein basS pmrB E3160_02260 ENOG4105XJC Two component transcriptional regulator (Winged helix family E3160_02265 ENOG4105DIJ Phosphoethanolamine transferase E3160_02270 ENOG4105D5Q Arginine ornithine antiporter E3160_02275 ENOG4106ZGR Transcriptional regulator E3160_02280 ENOG4105CXN decarboxylase E3160_02285 ENOG4108K2B transcriptional regulator E3160_02290 ENOG4105F8D glycoside hydrolase family 4 E3160_02295 ENOG4105CT4 transporter E3160_02305 ENOG4108R5S membrane E3160_02310 ENOG4107GFK fumarate E3160_02315 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E3160_02325 ENOG4108MRH transcriptional regulatory protein E3160_02330 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E3160_02335 ENOG4105VR1 Pfam:DUF1271 E3160_02340 ENOG410830R acetyltransferase E3160_02355 ENOG4105CRK lysyL-tRNA synthetase E3160_02360 ENOG4105DUX Transporter E3160_02365 ENOG4105CXN decarboxylase E3160_02370 ENOG4105D5Q Arginine ornithine antiporter E3160_02380 ENOG4108M3R transcriptional activator CadC E3160_02390 ENOG4108SIC Transcriptional regulator E3160_02395 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) E3160_02405 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E3160_02410 ENOG4108IJ0 Aspartate ammonia-lyase E3160_02415 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 E3160_02420 ENOG4105DVH amino acid E3160_02435 ENOG4108ZVF (LipO)protein E3160_02440 ENOG4105MTB Uncharacterized protein YjeJ E3160_02445 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein E3160_02455 ENOG4107PEH Entericidin EcnA/B family E3160_02460 ENOG4106BSU Entericidin B E3160_02465 ENOG4105KPY Small multidrug resistance protein E3160_02470 ENOG4105QNF Outer membrane lipoprotein E3160_02475 ENOG41066YJ Beta-lactamase E3160_02490 ENOG4105E33 succinate dehydrogenase E3160_02495 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E3160_02505 ENOG4107SC7 Inner membrane transporter yjeM E3160_02510 ENOG4105EGS Mechanosensitive ion channel E3160_02525 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) E3160_02555 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) E3160_02560 ENOG4105K8N protein family UPF0079, ATPase E3160_02565 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E3160_02585 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) E3160_02590 ENOG4107QJR hflk protein E3160_02595 ENOG4105EPW hflc protein E3160_02615 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) E3160_02620 ENOG4105C2N RNA methyltransferase TrmH family group 3 E3160_02625 ENOG4105FUX Conserved Protein E3160_02630 ENOG4108P9J Phage shock protein A E3160_02635 ENOG4107VNS Protein of unknown function (DUF2491) E3160_02640 ENOG4105Z6B inner membrane protein yjfl E3160_02645 ENOG4108KXT Conserved Protein E3160_02650 ENOG4106032 Glutathionylspermidine synthase E3160_02655 ENOG4105CSU acyl-Coa dehydrogenase E3160_02660 ENOG4105S17 UPF0379 protein yjfN E3160_02665 ENOG4105WSB biofilm stress and motility protein A E3160_02670 ENOG4108MXZ Esterase E3160_02685 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC E3160_02690 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport E3160_02695 ENOG4106ETB IIa component E3160_02715 ENOG4105KIT UPF0379 protein yjfY E3160_02730 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) E3160_02750 ENOG4108RS6 transposase E3160_02755 ENOG4105D7V transposase E3160_02765 ENOG4105FHY Opacity-associated protein A E3160_02770 ENOG4108V1T peptidylprolyl cis-trans isomerase E3160_02775 ENOG4105C85 amino acid E3160_02785 ENOG4105DXC membrane E3160_02790 ENOG4105ECR NmrA family E3160_02795 ENOG4105KVH Transcriptional regulator E3160_02800 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic E3160_02805 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase E3160_02815 ENOG4108UUE Transcriptional regulator E3160_02820 ENOG41061GZ Protein of unknown function (DUF1107) E3160_02825 ENOG4105C37 (CBS) domain E3160_02835 ENOG4105CFU surface antigen E3160_02840 ENOG4105MA0 exported protein E3160_02845 ENOG4108ZHD aig2 family E3160_02850 ENOG41087RY SpoVT_AbrB E3160_02855 ENOG4105MZG transcriptional modulator of maze toxin, mazf E3160_02860 ENOG4105F0N pyrophosphate phospho-hydrolase E3160_02865 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator E3160_02870 ENOG4105C2J ABC transporter E3160_02875 ENOG4107R9N ABC transporter E3160_02880 ENOG41062B0 ABC transporter, permease E3160_02890 ENOG4105DFU Cell wall formation (By similarity) E3160_02900 ENOG4105CMS peptidase U62, modulator of DNA gyrase E3160_02910 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) E3160_02915 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase E3160_02920 ENOG4105CG3 alpha amylase, catalytic region E3160_02925 ENOG4105C5Y PTS System E3160_02930 ENOG4105D4X repressor E3160_02940 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic E3160_02945 ENOG4105KME endoribonuclease L-psp E3160_02960 ENOG4107C93 pyrBI operon leader peptide E3160_02965 ENOG4108UQ8 endoribonuclease L-psp E3160_02970 ENOG4105F6U Short-chain dehydrogenase reductase Sdr E3160_02975 ENOG4108XFH Transcriptional regulator E3160_02980 ENOG4105XEP YhcH YjgK YiaL family protein E3160_02990 ENOG4105DBV ornithine carbamoyltransferase E3160_02995 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) E3160_03000 ENOG4108MJ3 acetyltransferase E3160_03005 ENOG4108M3P Membrane E3160_03015 ENOG4105MYG DNA polymerase iii, chi subunit E3160_03025 ENOG4108M8S permease YjgP YjgQ family protein E3160_03030 ENOG4108K5H permease YjgP YjgQ family protein E3160_03035 ENOG4105D7A ATP-binding protein E3160_03040 ENOG4105DQ4 alcohol dehydrogenase E3160_03135 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) E3160_03145 ENOG4108I5C dEAD DEAH box helicase E3160_03150 ENOG4105C4R Atp-dependent dna helicase E3160_03165 ENOG4108YXQ IS66 Orf2 family protein E3160_03170 ENOG4105E5H Transposase E3160_03185 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) E3160_03190 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria E3160_03195 ENOG4108W9T type 1 fimbriae regulatory protein E3160_03200 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off E3160_03210 ENOG4108S54 Fimbrial protein E3160_03215 ENOG4108NAE Fimbrial chaperone protein E3160_03220 ENOG4105CW0 outer membrane usher protein E3160_03225 ENOG4108SQA Fimbrial E3160_03230 ENOG4108T65 Fimbrial E3160_03235 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin E3160_03240 ENOG4107EFN gluconate transport system permease 3 E3160_03250 ENOG4105DEI Mannitol dehydrogenase E3160_03255 ENOG4105C6F GntR Family Transcriptional Regulator E3160_03280 ENOG4105DYB Isoaspartyl dipeptidase E3160_03285 ENOG4108P2H Inner membrane protein YjiG E3160_03290 ENOG41074DU domain protein E3160_03300 ENOG4105CBP Major Facilitator E3160_03305 ENOG4108ZK4 sdia-regulated domain-containing protein E3160_03325 ENOG4105CIZ coA-substrate-specific enzyme activase E3160_03330 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase E3160_03335 ENOG4106BRA Membrane E3160_03340 ENOG41083G8 Multidrug resistance protein MdtM E3160_03355 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E3160_03360 ENOG4106DIZ Domain of unknown function (DUF1127) E3160_03380 ENOG4107QTH restriction modification system DNA specificity domain E3160_03390 ENOG4108F3G Type I restriction-modification system, R subunit E3160_03405 ENOG4105CKI cobalamin synthesis protein E3160_03410 ENOG4105VCD cytoplasmic protein E3160_03415 ENOG4105D22 carbon starvation protein E3160_03425 ENOG4105C8Q Methyl-accepting chemotaxis E3160_03430 ENOG4108I5G Major Facilitator superfamily E3160_03435 ENOG410617M Transcriptional regulator E3160_03440 ENOG4105CPQ Dehydrogenase E3160_03450 ENOG4105RI1 glycoprotein receptor E3160_03455 ENOG4106CVF DNA replication protein E3160_03470 ENOG4105DWK Membrane E3160_03475 ENOG4108N8T regulatoR E3160_03480 ENOG4108T94 DNA-binding transcriptional activator BglJ E3160_03485 ENOG4108819 ferric iron reductase E3160_03490 ENOG4105YBH Protein of unknown function (DUF1435) E3160_03505 ENOG4108WPU DNA polymerase III subunit psi E3160_03510 ENOG4105KEG ribosomal-protein-alanine acetyltransferase E3160_03515 ENOG4105PAD Hydrolase E3160_03525 ENOG4105K3G Periplasmic Protein E3160_03535 ENOG4108NRW Phospholipase, patatin family E3160_03540 ENOG4105EYA deoxyribonuclease E3160_03545 ENOG41076CZ activating enzyme E3160_03580 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) E3160_03585 ENOG41062Z9 Membrane E3160_03590 ENOG4105EAC phosphoserine phosphatase E3160_03595 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) E3160_03600 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase E3160_03605 ENOG4105C5H ABC transporter E3160_03610 ENOG4107SC1 transglycosylase E3160_03620 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) E3160_03630 ENOG4105UEI Transcriptional Regulator AraC Family E3160_03635 ENOG4108RH0 Crea protein E3160_03640 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3160_03645 ENOG4105EB3 Histidine kinase E3160_03650 ENOG4105CT7 inner membrane cred family protein E3160_03655 ENOG41065U4 response regulator E3160_03660 ENOG410759A E3160_03665 ENOG4106FVC RNA methyltransferase E3160_03675 ENOG4105CFH Aspartokinase E3160_03685 ENOG4105D98 threonine synthase E3160_03690 ENOG41062C6 Protein of unknown function (DUF2502) E3160_03700 ENOG4105BZG amino acid carrier protein E3160_03705 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E3160_03710 ENOG4108RIR Molybdenum cofactor biosynthesis protein E3160_03715 ENOG4106HK8 GPR1 FUN34 yaaH family protein E3160_03720 ENOG4108QUJ UPF0174 protein YaaW E3160_03740 ENOG4105WI6 cell killing protein encoded within cryptic prophage E3160_03750 ENOG41063Z6 transcriptional regulator, lysR family E3160_03760 ENOG4105CW0 outer membrane usher protein E3160_03765 ENOG4108MQF Chaperone E3160_03785 ENOG410647N response to DNA damage stimulus E3160_03790 ENOG4105DTN riboflavin biosynthesis protein ribF E3160_03805 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase E3160_03825 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain E3160_03830 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain E3160_03835 ENOG4108XNW Transcriptional activatory protein CaiF E3160_03845 ENOG4106YT9 Enoyl-CoA hydratase E3160_03880 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3160_03885 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein E3160_03890 ENOG4105C54 Major Facilitator superfamily E3160_03905 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) E3160_03940 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) E3160_03945 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) E3160_03950 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) E3160_03965 ENOG4105D3G Pseudouridine synthase E3160_03970 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) E3160_03975 ENOG4105CQ2 DNA polymerase E3160_03980 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase E3160_03995 ENOG41063TF transcriptional regulator (AraC E3160_04000 ENOG4108KF1 Membrane E3160_04005 ENOG4107T0D ABC, transporter E3160_04010 ENOG4106SMU thiamine transporter membrane protein E3160_04015 ENOG4105DP9 ABC transporter E3160_04035 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) E3160_04055 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) E3160_04070 ENOG41064T2 transcriptional regulator, lysR family E3160_04075 ENOG4105C7K acetolactate synthase E3160_04080 ENOG4108ZP8 Acetolactate synthase small subunit E3160_04090 ENOG4107B7Y DNA-binding transcriptional regulator FruR E3160_04105 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) E3160_04110 ENOG4105CJN penicillin-binding protein E3160_04115 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) E3160_04120 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) E3160_04130 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) E3160_04135 ENOG4105CNI cell division protein FtsW E3160_04150 ENOG4105CPF Cell wall formation (By similarity) E3160_04155 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) E3160_04160 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) E3160_04165 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) E3160_04185 ENOG4105M6F mutator MutT protein E3160_04200 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) E3160_04210 ENOG4105D7Q type ii secretion system E3160_04215 ENOG4107QHF type ii secretion system protein e E3160_04220 ENOG4108ZUW Major pilin subunit E3160_04225 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase E3160_04230 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase E3160_04235 ENOG4106A72 regulatory protein AmpE E3160_04240 ENOG4105C85 amino acid E3160_04245 ENOG41073TP transcriptional regulator E3160_04250 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) E3160_04255 ENOG4107QSN dihydrolipoamide acetyltransferase E3160_04260 ENOG4107QN2 dihydrolipoyl dehydrogenase E3160_04265 ENOG4108NST exported protein E3160_04270 ENOG4107QIJ Aconitate hydratase 2 E3160_04290 ENOG4108ZRK uncharacterized protein yacC E3160_04295 ENOG4105E3B Multicopper oxidase E3160_04300 ENOG4105DZG Dehydrogenase E3160_04305 ENOG4108UGV hypoxanthine phosphoribosyltransferase E3160_04310 ENOG41077A9 carbonic anhydrase E3160_04315 ENOG4105DA5 (ABC) transporter E3160_04320 ENOG4105E3A (ABC) transporter E3160_04325 ENOG4108YTN IIa component E3160_04330 ENOG4107BJW polysaccharide deacetylase E3160_04340 ENOG4108A32 Transposase E3160_04365 ENOG4105SYG Fimbrial protein E3160_04370 ENOG4108XEY fimbrial-like adhesin protein E3160_04375 ENOG4105CW0 outer membrane usher protein E3160_04380 ENOG4108VEV chaperone E3160_04390 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase E3160_04395 ENOG4105DJ0 Poly(A) Polymerase E3160_04400 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) E3160_04415 ENOG4107XID 2'-5' rna ligase E3160_04420 ENOG4105CQ7 ATP-dependent helicase E3160_04425 ENOG4105BZ4 penicillin-binding protein E3160_04430 ENOG4105E0K tonB-dependent siderophore receptor E3160_04435 ENOG4105E0A ABC, transporter E3160_04440 ENOG4105J76 Periplasmic binding protein E3160_04445 ENOG4105S6R Iron-hydroxamate transporter permease subunit E3160_04470 ENOG4105EN6 Membrane E3160_04475 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) E3160_04490 ENOG4105C0H protease E3160_04495 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR E3160_04515 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) E3160_04540 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) E3160_04545 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) E3160_04550 ENOG4105KNE Phosphatidate cytidylyltransferase E3160_04555 ENOG4105DZP Membrane-associated zinc metalloprotease E3160_04565 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) E3160_04570 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) E3160_04595 ENOG4105C0B DNA polymerase III (alpha subunit) E3160_04605 ENOG4105CXN decarboxylase E3160_04610 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase E3160_04615 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) E3160_04620 ENOG4105M1T rho-binding antiterminator E3160_04630 ENOG4108VWS Yaeq family E3160_04635 ENOG4108YZN class I peptide chain release factor E3160_04640 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion E3160_04645 ENOG4108UY0 (LipO)protein E3160_04655 ENOG4108R96 Methyltransferase, YaeB family E3160_04660 ENOG4108R8X outer membrane lipoprotein E3160_04665 ENOG4105D01 (LipO)protein E3160_04670 ENOG4108UMI ABC transporter, permease E3160_04675 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) E3160_04680 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase E3160_04715 ENOG4105CV8 reductase E3160_04720 ENOG4105HEI LysR family (Transcriptional regulator E3160_04730 ENOG4105F2W methyltransferase E3160_04735 ENOG4105E9H Lytic Murein transglycosylase E3160_04740 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) E3160_04745 ENOG4105D1A Methyltransferase E3160_04755 ENOG4107RZZ dna polymerase iii epsilon subunit E3160_04765 ENOG410600K aminopeptidase E3160_04815 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E3160_04870 ENOG4108WC9 type VI secretion system effector, hcp1 family E3160_04875 ENOG4105CS6 Rhs element vgr protein E3160_04880 ENOG4105CNA YD repeat protein E3160_04890 ENOG4105CNA YD repeat protein E3160_04905 ENOG410600T transposase E3160_04910 ENOG4107TV1 YD repeat protein E3160_04925 ENOG410600T transposase E3160_04930 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E3160_04935 ENOG4108WN0 inhibitor of vertebrate lysozyme E3160_04940 ENOG4107QPN acyl-Coa dehydrogenase E3160_04950 ENOG4105E7A Glutamine amidotransferase E3160_04955 ENOG4105F7V ErfK ybiS ycfS ynhG family protein E3160_04960 ENOG4105VXN addiction module toxin, RelE StbE family E3160_04970 ENOG4108YS0 lipoprotein YafL E3160_04990 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E3160_04995 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system E3160_05000 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome E3160_05005 ENOG4108HYG acetyltransferase E3160_05015 ENOG4108S2Y peptide Chain Release factor E3160_05020 ENOG4105CIN aminoacyl-histidine dipeptidase E3160_05040 ENOG4105FCK Membrane E3160_05070 ENOG4105DFP Integrase E3160_05145 ENOG4105EMU Dehydrogenase E3160_05160 ENOG4105EQ2 LysR family Transcriptional regulator E3160_05165 ENOG4105ENX hydrolase E3160_05170 ENOG4107RTG Major Facilitator superfamily E3160_05175 ENOG4107XAN XdhC and CoxI family E3160_05180 ENOG4105C7W Xanthine dehydrogenase E3160_05190 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit E3160_05195 ENOG4105R3P Inner membrane protein yagU E3160_05200 ENOG4105PI0 Ferredoxin E3160_05205 ENOG4108UD7 cell wall organization E3160_05210 ENOG4106PYX Receptor E3160_05215 ENOG4108N3D putative enzyme E3160_05225 ENOG4108GWT fimbrillin MatB E3160_05260 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E3160_05265 ENOG4105ENX hydrolase E3160_05270 ENOG410642W LysR family Transcriptional regulator E3160_05275 ENOG4105E5H Transposase E3160_05280 ENOG4108YXQ IS66 Orf2 family protein E3160_05315 ENOG4105CV8 reductase E3160_05320 ENOG4108KBJ Inner membrane protein YkgB E3160_05325 ENOG41066GK UPF0379 protein ykgI E3160_05330 ENOG4107QN2 dihydrolipoyl dehydrogenase E3160_05335 ENOG4108K01 transcriptional regulator E3160_05340 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E3160_05345 ENOG4107QR9 Iron-sulfur cluster binding protein E3160_05350 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) E3160_05365 ENOG4105I1J Autotransporter E3160_05405 ENOG4105C94 Transporter E3160_05415 ENOG4105BZU Histidine kinase E3160_05430 ENOG4107SNB ankyrin repeat protein YahD E3160_05435 ENOG4105N16 Protein of unknown function (DUF2877) E3160_05440 ENOG4107R1Q Membrane protein FdrA E3160_05445 ENOG4107REC cytoplasmic protein E3160_05455 ENOG4105C5B carbamate kinase E3160_05460 ENOG4105DZC cytosine deaminase E3160_05470 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E3160_05475 ENOG4105C2J ABC transporter E3160_05480 ENOG4105CNN ABC, transporter E3160_05485 ENOG4105CNN ABC, transporter E3160_05490 ENOG4105DQ4 alcohol dehydrogenase E3160_05505 ENOG4105E82 cytochrome subunit of dehydrogenase E3160_05510 ENOG4105TDT uncharacterized protein yahO E3160_05515 ENOG4108JU7 Transcriptional regulator E3160_05520 ENOG4105CR4 methylisocitrate lyase E3160_05525 ENOG4105BZN citrate synthase E3160_05530 ENOG4105DXD 2-methylcitrate dehydratase E3160_05535 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E3160_05540 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin E3160_05545 ENOG4105DZC cytosine deaminase E3160_05550 ENOG4105DND Transcriptional regulator E3160_05555 ENOG4107B2H carbonic anhydrase E3160_05565 ENOG4105DJ2 Major Facilitator Superfamily E3160_05570 ENOG4108UW5 maltose o-acetyltransferase E3160_05575 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) E3160_05580 ENOG4105CNT hydrolase family 2 E3160_05585 ENOG4105ETE Transcriptional regulator (LacI family E3160_05595 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein E3160_05600 ENOG4108K2P TRANSCRIPTIONal E3160_05615 ENOG4106HB6 Alpha beta hydrolase E3160_05630 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) E3160_05635 ENOG4108SC4 )-transporter E3160_05640 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme E3160_05645 ENOG4105C4W S-formylglutathione hydrolase E3160_05660 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3160_05665 ENOG4107RCV ABC transporter, permease E3160_05670 ENOG4105C4Y ABC transporter E3160_05675 ENOG4105CXY transporter E3160_05680 ENOG4105BZU Histidine kinase E3160_05685 ENOG4108KX4 response regulator E3160_05690 ENOG4106FTQ Taurine ABC transporter, periplasmic E3160_05695 ENOG4108ETV ABC transporter E3160_05700 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component E3160_05705 ENOG4105E2B Taurine dioxygenase E3160_05710 ENOG4105D52 delta-aminolevulinic acid dehydratase E3160_05720 ENOG4108PNB DNA-binding transcriptional regulator E3160_05725 ENOG4107R6D beta-lactam binding protein AmpH E3160_05730 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 E3160_05735 ENOG4107QS8 (LipO)protein E3160_05740 ENOG4105FR5 inner membrane protein YaiY E3160_05745 ENOG4105UNH Membrane E3160_05750 ENOG4105CPF Cell wall formation (By similarity) E3160_05760 ENOG4105G6Z alkaline phosphatase E3160_05765 ENOG4105VIF phosphate starvation-inducible protein E3160_05770 ENOG4105BZU Histidine kinase E3160_05775 ENOG4105II7 pyrroline-5-carboxylate reductase E3160_05790 ENOG4105SS3 E3160_05795 ENOG4105HBA AroM protein E3160_05820 ENOG4105DKQ ROK family E3160_05825 ENOG4105F27 Major Facilitator E3160_05830 ENOG4105EYH Exonuclease E3160_05835 ENOG4107RH8 nuclease SbcCD subunit D E3160_05840 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E3160_05845 ENOG4105BZU Histidine kinase E3160_05850 ENOG4105CWM branched-chain amino acid transport system II carrier protein E3160_05855 ENOG4105C85 amino acid E3160_05860 ENOG4107R28 alpha amylase, catalytic region E3160_05885 ENOG4105VIE preprotein translocase, subunit YajC E3160_05890 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E3160_05895 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E3160_05900 ENOG4105X54 addiction module antidote protein E3160_05910 ENOG4105N1F Hnh endonuclease E3160_05915 ENOG4105DRB nucleoside-specific channel-forming protein E3160_05920 ENOG4108KIC (LipO)protein E3160_05930 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) E3160_05935 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) E3160_05945 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) E3160_05950 ENOG4108ZAI phosphatidylglycerophosphatase a E3160_05960 ENOG4105CPC Aldo Keto reductase E3160_05970 ENOG4105CTB Polyprenyl synthetase E3160_05985 ENOG4107S0N DJ-1 family E3160_05990 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) E3160_06000 ENOG4107RDB Major Facilitator E3160_06010 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) E3160_06015 ENOG4105CCU oxidase (Subunit III) E3160_06020 ENOG4105BZ9 Cytochrome C oxidase, subunit I E3160_06025 ENOG4105E2S oxidase) subunit II E3160_06030 ENOG4105EYM Major Facilitator superfamily E3160_06035 ENOG4105IEY (LipO)protein E3160_06040 ENOG4105M85 Bola protein E3160_06060 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) E3160_06065 ENOG4105K70 DNA-binding protein E3160_06070 ENOG4105EIN peptidylprolyl cis-trans isomerase E3160_06075 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein E3160_06080 ENOG4108TGP Thioesterase superfamily protein E3160_06090 ENOG4108NFA extracellular solute-binding protein E3160_06100 ENOG4108XM1 transcriptional regulator AsnC family E3160_06105 ENOG4105BZ1 (ABC) transporter E3160_06110 ENOG4105BZ1 (ABC) transporter E3160_06115 ENOG4108YZA Nitrogen regulatory protein pii E3160_06120 ENOG4105BZU Histidine kinase E3160_06125 ENOG4105C29 acyl-CoA thioesterase E3160_06130 ENOG4108MNP Glycoprotein polysaccharide metabolism E3160_06135 ENOG41080UX Methyltransferase E3160_06145 ENOG4105KCV RNA signal recognition particle 4.5S RNA E3160_06150 ENOG41066DG (EAL) domain protein E3160_06155 ENOG4105GSJ Inner membrane protein ylaC E3160_06160 ENOG4108UW5 maltose o-acetyltransferase E3160_06165 ENOG4105KF5 hemolysin expression-modulating protein E3160_06170 ENOG4108UKR Biofilm formation regulator YbaJ E3160_06175 ENOG4105BZS acriflavin resistance protein E3160_06180 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3160_06185 ENOG4107XI7 Tetr family transcriptional regulator E3160_06190 ENOG4105EGS Mechanosensitive ion channel E3160_06195 ENOG4106428 Protein of unknown function (DUF2496) E3160_06200 ENOG4108URS primosomal replication protein n'' E3160_06205 ENOG4105WD1 Membrane E3160_06215 ENOG4107QMP dna polymerase iii subunits gamma and tau E3160_06250 ENOG4107RE1 Inosine-guanosine kinase E3160_06255 ENOG4105CKD glutathione-regulated potassium-efflux system protein E3160_06260 ENOG4105EU0 Major facilitator Superfamily E3160_06265 ENOG4105CGH 5'-nucleotidase E3160_06270 ENOG4108Z66 YbaK ebsC protein E3160_06275 ENOG4105MBR gumn family E3160_06285 ENOG41081XE plasmid maintenance system antidote protein, xre family E3160_06290 ENOG4105C59 p-type ATPase E3160_06295 ENOG4105CSV Glutaminase E3160_06300 ENOG4107RY6 amino acid E3160_06325 ENOG4107QZV Type I secretion membrane fusion protein E3160_06355 ENOG4105G5H Membrane E3160_06360 ENOG4107QX8 SPFH domain, Band 7 family protein E3160_06365 ENOG41083J0 (ABC) transporter E3160_06370 ENOG4105C4B ABC transporter, permease E3160_06375 ENOG4107QR8 Thioredoxin E3160_06380 ENOG4105E1F short-chain dehydrogenase reductase E3160_06385 ENOG4108UJV acyl-CoA thioesterase i E3160_06390 ENOG4108I0Y (ABC) transporter E3160_06395 ENOG4105CV6 ABC transporter, permease E3160_06400 ENOG4105CNA YD repeat protein E3160_06420 ENOG4107653 Transcriptional regulator E3160_06430 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region E3160_06435 ENOG41060W2 glyoxylate carboligase E3160_06440 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) E3160_06445 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3160_06450 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease E3160_06460 ENOG4105DTE Xanthine uracil vitamin C permease E3160_06465 ENOG4105BZW Glycerate kinase E3160_06470 ENOG4105S0E allantoin catabolism protein E3160_06475 ENOG4105CE7 Amidase, hydantoinase carbamoylase family E3160_06480 ENOG4105DG4 malate L-lactate dehydrogenase E3160_06485 ENOG4107R1Q Membrane protein FdrA E3160_06490 ENOG4107REC cytoplasmic protein E3160_06495 ENOG4105G5A Protein of unknown function (DUF2877) E3160_06500 ENOG4105C5B carbamate kinase E3160_06505 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit E3160_06510 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) E3160_06520 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E3160_06530 ENOG4105S2T inner membrane protein YbcI E3160_06535 ENOG4105WQ3 Rna-binding protein E3160_06545 ENOG4108WDE Fimbrial protein E3160_06550 ENOG4108AF8 Chaperone E3160_06555 ENOG4105CW0 outer membrane usher protein E3160_06560 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) E3160_06565 ENOG4108ZI2 Fimbrial protein E3160_06570 ENOG4108Q9V regulatoR E3160_06585 ENOG4105QUW E3160_06590 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit E3160_06600 ENOG410600T transposase E3160_06610 ENOG4105CNA YD repeat protein E3160_06625 ENOG4105CNA YD repeat protein E3160_06650 ENOG4105CS6 Rhs element vgr protein E3160_06655 ENOG4105GR3 Histidine kinase E3160_06660 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E3160_06665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein E3160_06670 ENOG410624V efflux system protein E3160_06675 ENOG4105EP1 Efflux transporter rnd family, mfp subunit E3160_06680 ENOG4108IJF Heavy metal efflux pump, CzcA E3160_06685 ENOG4105C85 amino acid E3160_06690 ENOG4105CUY Mechanosensitive ion channel E3160_06695 ENOG4108RCM Nitroreductase E3160_06700 ENOG4105MSB protein, conserved in bacteria E3160_06705 ENOG4105WQ6 Membrane E3160_06720 ENOG4107635 Hok Gef family protein E3160_06735 ENOG4108TSE Transferase E3160_06740 ENOG4107RNH Outer membrane receptor FepA E3160_06745 ENOG4105E93 esterase E3160_06750 ENOG41085A6 mbth domain-containing protein E3160_06755 ENOG4105C0W non-ribosomal peptide synthetase E3160_06760 ENOG4108QY5 Ferric enterobactin transport protein E3160_06765 ENOG4105E0A ABC, transporter E3160_06770 ENOG4105TVJ transport system, permease E3160_06775 ENOG4105DQ5 transport system permease protein E3160_06785 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein E3160_06790 ENOG4105E4F Isochorismate synthase E3160_06795 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase E3160_06800 ENOG4105WQI isochorismatase E3160_06805 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase E3160_06815 ENOG4105D22 carbon starvation protein E3160_06820 ENOG4105VCD cytoplasmic protein E3160_06825 ENOG4107SCQ Iron-containing alcohol dehydrogenase E3160_06830 ENOG4105CHM Aminotransferase E3160_06835 ENOG4105GTN ParB Domain Protein Nuclease E3160_06840 ENOG4105BZV Phosphoadenosine phosphosulfate reductase E3160_06845 ENOG4105DQS Transcriptional regulator E3160_06850 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase E3160_06855 ENOG4105D3R alkyl hydroperoxide reductase E3160_06860 ENOG4108JU3 Alkyl hydroperoxide reductase E3160_06865 ENOG4108U51 Universal stress protein E3160_06870 ENOG4105E2A Dehydrogenase E3160_06875 ENOG4105NXH GreA GreB family elongation factor E3160_06880 ENOG4105KTS ribonuclease E3160_06885 ENOG4107QPK )-transporter E3160_06890 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase E3160_06900 ENOG4105CHY citrate lyase, alpha E3160_06905 ENOG4105CI0 Citrate lyase E3160_06915 ENOG4105DUA (citrate (pro-3S)-lyase ligase E3160_06920 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E3160_06925 ENOG4106YYS transcriptional regulatory protein E3160_06930 ENOG4105CEE C4-dicarboxylate transporter E3160_06935 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) E3160_06955 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) E3160_06965 ENOG41064T2 transcriptional regulator, lysR family E3160_06980 ENOG4105DZ1 carboxypeptidase E3160_06985 ENOG4105K6T rare lipoprotein A E3160_06990 ENOG4105CNI cell division protein FtsW E3160_06995 ENOG4105CJN penicillin-binding protein E3160_07005 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) E3160_07010 ENOG4108TGR phosphatase E3160_07020 ENOG4105DJF DNA polymerase III, delta' subunit E3160_07035 ENOG4107PAI alpha helical protein E3160_07045 ENOG41069CF Protein of unknown function (DUF1266) E3160_07050 ENOG4105QFC Hsc56 co-chaperone of HscC E3160_07055 ENOG4107JFD Sel1 repeat E3160_07060 ENOG41069CF Protein of unknown function (DUF1266) E3160_07065 ENOG4105QFC Hsc56 co-chaperone of HscC E3160_07070 ENOG4105QFC Hsc56 co-chaperone of HscC E3160_07075 ENOG4105F7F Chaperone E3160_07085 ENOG4105CDA abc transporter atp-binding protein E3160_07090 ENOG4105DRP amino acid AbC transporter E3160_07095 ENOG4105EAD ABC transporter E3160_07100 ENOG4107RP9 extracellular solute-binding protein, family 3 E3160_07105 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) E3160_07110 ENOG4108JU5 Magnesium and cobalt efflux protein E3160_07120 ENOG4105C9A Phoh family E3160_07130 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E3160_07170 ENOG4105CAQ asparagine synthetase E3160_07175 ENOG4105D4U had-superfamily hydrolase, subfamily iia E3160_07180 ENOG4105E2R ROK family E3160_07185 ENOG4105CE4 GlcNAc 6-P deacetylase E3160_07195 ENOG4105CI1 PTS System E3160_07215 ENOG4105GX6 (LipO)protein E3160_07220 ENOG41090R7 Ferric uptake E3160_07230 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) E3160_07235 ENOG4105NNH LexA regulated protein E3160_07240 ENOG4105EV9 Alpha Beta Hydrolase E3160_07245 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) E3160_07250 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 E3160_07255 ENOG4105D5Q Arginine ornithine antiporter E3160_07260 ENOG4105CXN decarboxylase E3160_07275 ENOG4105EEX Two component transcriptional regulator (Winged helix family E3160_07280 ENOG4105C08 Histidine kinase E3160_07305 ENOG4105XIQ Protein of unknown function (DUF2517) E3160_07310 ENOG4105CNA YD repeat protein E3160_07315 ENOG4106R09 E3160_07335 ENOG410600T transposase E3160_07340 ENOG4107SEY Conserved Protein E3160_07345 ENOG4105CVP deoxyribo-dipyrimidine photolyase E3160_07350 ENOG4105DUX Transporter E3160_07355 ENOG4107QNR UPF0135 protein E3160_07360 ENOG4105P4J Allophanate hydrolase, subunit 1 E3160_07365 ENOG4107R7A Allophanate hydrolase subunit 2 E3160_07375 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) E3160_07380 ENOG4108KK1 membrane protein AbrB duplication E3160_07385 ENOG4108MY7 Fimbrial E3160_07390 ENOG4108TTM chaperone E3160_07410 ENOG4106UBK fimbrial-like adhesin protein E3160_07415 ENOG4105BZN citrate synthase E3160_07425 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit E3160_07430 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein E3160_07435 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E3160_07440 ENOG4105E33 succinate dehydrogenase E3160_07445 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 E3160_07450 ENOG4105C7S Dehydrogenase E3160_07460 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha E3160_07475 ENOG4105ETT transcriptional Regulator, LysR family E3160_07480 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase E3160_07485 ENOG4107GFK fumarate E3160_07510 ENOG4105DJI Methylaspartate mutase, E subunit E3160_07520 ENOG4107WFU Glutamate mutase subunit sigma E3160_07535 ENOG4105C4M (Ubiquinol oxidase) subunit I E3160_07540 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E3160_07550 ENOG4105KJB cyd operon protein YbgE E3160_07555 ENOG4107YD3 Thioesterase E3160_07560 ENOG4105E02 MotA TolQ exbB proton channel E3160_07570 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA E3160_07580 ENOG4105KCK Peptidoglycan-associated lipoprotein E3160_07585 ENOG4105UFD tol-pal system protein YbgF E3160_07615 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) E3160_07620 ENOG4106Z1T Nicotinamide Mononucleotide Transporter E3160_07625 ENOG4105PGM cation diffusion facilitator family transporter E3160_07630 ENOG4105JND homeobox protein E3160_07635 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3160_07645 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) E3160_07655 ENOG4105F0Z galactose-1-phosphate uridylyltransferase E3160_07660 ENOG4105CMR udp-glucose 4-epimerase E3160_07665 ENOG4105DKW ABC transporter E3160_07670 ENOG4105F4R Transcriptional regulator mode E3160_07680 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein E3160_07685 ENOG4105E0C molybdate abc transporter E3160_07695 ENOG4108K4B hydrolase E3160_07705 ENOG4105F04 LysR family Transcriptional regulator E3160_07710 ENOG4105C7F AcnD-accessory protein PrpF E3160_07715 ENOG4107QPK )-transporter E3160_07720 ENOG4107QM5 aconitate hydratase E3160_07725 ENOG4105NBR Pectinesterase E3160_07730 ENOG4108I1J Integrase E3160_07820 ENOG4105NY2 NinB protein E3160_07840 ENOG4108R1E Serine threonine protein phosphatase 1 E3160_07880 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_07885 ENOG4105KUS lysozyme E3160_07890 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 E3160_07935 ENOG4105UZW Tail fiber assembly protein E3160_07955 ENOG4108V1U phospholipid-binding protein E3160_07960 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) E3160_07975 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) E3160_07980 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E3160_07990 ENOG4105CHW UPF0052 protein E3160_08000 ENOG4108RIR Molybdenum cofactor biosynthesis protein E3160_08010 ENOG4105M00 molybdopterin converting factor, subunit 1 E3160_08015 ENOG4108ZAF Molybdopterin E3160_08020 ENOG4105HFZ Membrane E3160_08030 ENOG410733J conserved inner membrane protein E3160_08035 ENOG4107UXM Membrane E3160_08040 ENOG4105DZQ phospholipase D Transphosphatidylase E3160_08045 ENOG4105X23 Endonuclease Exonuclease phosphatase E3160_08050 ENOG4105I9U inner membrane protein ybhQ E3160_08055 ENOG4107QWP ABC-2 type transporter E3160_08060 ENOG4107QWP ABC-2 type transporter E3160_08065 ENOG4105CJ1 ABC, transporter E3160_08075 ENOG4107MVR Transcriptional regulator E3160_08080 ENOG4105C1J atp-dependent rna helicase E3160_08090 ENOG4105DVT helicase E3160_08095 ENOG4108MTB glycosyl transferase family E3160_08100 ENOG4105DG4 malate L-lactate dehydrogenase E3160_08105 ENOG4105VR4 UPF0379 protein ybiJ E3160_08110 ENOG4105KSC Transcriptional regulator, TraR DksA family E3160_08120 ENOG4108ESX Receptor E3160_08125 ENOG4105ZY9 UPF0379 protein ybiM E3160_08135 ENOG4105D8X mechanosensitive ion channel E3160_08140 ENOG4105CDA abc transporter atp-binding protein E3160_08145 ENOG4105E5Q amino acid AbC transporter E3160_08150 ENOG4107R0W ABC transporter E3160_08160 ENOG4107AQZ Membrane E3160_08170 ENOG4108T1M outer membrane protein x E3160_08175 ENOG4108I6E Sulfatase E3160_08185 ENOG4105KST dependent repressor E3160_08190 ENOG4105F4P )-transporter E3160_08195 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3160_08200 ENOG4105C5H ABC transporter E3160_08205 ENOG41072TH Protein of unknown function (DUF1479) E3160_08210 ENOG4108HCJ Hydrolase E3160_08220 ENOG4105F1A Pyruvate formate-lyase E3160_08225 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E3160_08230 ENOG4105D06 uba thif-type nad fad binding protein E3160_08235 ENOG4105CVM Molybdenum cofactor synthesis domain protein E3160_08240 ENOG4105D44 asparaginase E3160_08245 ENOG4105D44 asparaginase E3160_08250 ENOG4108JQ6 ABC transporter E3160_08255 ENOG4105DEF Extracellular solute-binding protein, family 5 E3160_08260 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3160_08270 ENOG4105BZU Histidine kinase E3160_08275 ENOG41064RH membrane protein YliF E3160_08295 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway E3160_08300 ENOG4105D8V Glucose sorbosone dehydrogenase E3160_08305 ENOG4108TGY Glutathione S-transferase E3160_08310 ENOG4105DZ1 carboxypeptidase E3160_08315 ENOG4107FB0 transcriptional regulator DeoR family E3160_08320 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase E3160_08325 ENOG4107QF7 multi-drug E3160_08335 ENOG4108HCJ Hydrolase E3160_08340 ENOG4106UW1 Major Facilitator superfamily E3160_08345 ENOG4108RFG Tetr family transcriptional regulator E3160_08355 ENOG4105GWF inner membrane protein YbjM E3160_08360 ENOG41090BQ Glutaredoxin E3160_08365 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress E3160_08370 ENOG4108DBC nitroreductase E3160_08380 ENOG4108RMJ sensory transduction regulator E3160_08385 ENOG4107RUE extracellular solute-binding protein family 1 E3160_08390 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3160_08395 ENOG4105F38 ABC transporter, permease E3160_08400 ENOG4105D38 putrescine abc transporter E3160_08405 ENOG4105RBQ inner membrane protein ybjO E3160_08430 ENOG4106TNF Periplasmic binding protein E3160_08435 ENOG4105DMR ABC, transporter E3160_08440 ENOG4105GBT ABC transporter E3160_08445 ENOG4106PMH Extracellular solute-binding protein family 3 E3160_08450 ENOG4105E5Z arginine transporter ATP-binding subunit E3160_08455 ENOG41064MM (LipO)protein E3160_08480 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase E3160_08485 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase E3160_08490 ENOG4105CGD Nad-dependent epimerase dehydratase E3160_08495 ENOG4105C5W Aldolase E3160_08500 ENOG4105C7K acetolactate synthase E3160_08505 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E3160_08515 ENOG4105DWU Membrane E3160_08525 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E3160_08530 ENOG4105CPB ATP-dependent endonuclease of the OLD family E3160_08535 ENOG4108MJ5 VirK protein E3160_08540 ENOG4105DJY efflux transporter, rnd family, mfp subunit E3160_08545 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) E3160_08550 ENOG4105VEQ Cold shock protein E3160_08560 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E3160_08570 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) E3160_08580 ENOG4108JJ8 (ABC) transporter E3160_08585 ENOG4108JJ9 ABC, transporter E3160_08590 ENOG4105C3M thioredoxin reductase E3160_08600 ENOG4105CNU cell division protein FtsK E3160_08610 ENOG4105D1H recombination factor protein RarA E3160_08620 ENOG4107QY8 reductase E3160_08625 ENOG4105QAX Iron-sulfur E3160_08630 ENOG4107KGK dmso reductase anchor subunit E3160_08645 ENOG4105E5D amino acid E3160_08655 ENOG4105F1A Pyruvate formate-lyase E3160_08660 ENOG4105C6N Formate acetyltransferase E3160_08665 ENOG4105TMB Formate nitrite transporter E3160_08670 ENOG4105DDY UPF0142 protein ycaO E3160_08675 ENOG4107VMU Membrane E3160_08690 ENOG4108K0D peptidase, M48 E3160_08700 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) E3160_08710 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 E3160_08715 ENOG4105BZ1 (ABC) transporter E3160_08725 ENOG4105T0Z Conserved Protein E3160_08740 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups E3160_08745 ENOG4107S90 membrAne E3160_08750 ENOG4106371 Methyltransferase E3160_08760 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) E3160_08770 ENOG4105DIT ErfK YbiS YcfS YnhG family protein E3160_08775 ENOG4105EAQ (twin-arginine translocation) pathway signal E3160_08780 ENOG4105C5X domain protein E3160_08785 ENOG4105CGF Aromatic amino acid aminotransferase E3160_08790 ENOG4105FCK Membrane E3160_08795 ENOG4105C5S asparaginyl-tRNA synthetase E3160_08805 ENOG4105CD8 aminopeptidase N E3160_08810 ENOG4105E2Y ABC, transporter E3160_08815 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component E3160_08825 ENOG4105GVF (ABC) transporter E3160_08830 ENOG4108UZX fmn reductase E3160_08835 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon E3160_08840 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae E3160_08850 ENOG4108MDY Fimbrial E3160_08855 ENOG4105Q7J Fimbrial E3160_08860 ENOG4105MX3 Fimbrial E3160_08875 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) E3160_08880 ENOG4105QVC MOSC domain-containing protein E3160_08890 ENOG4105C5H ABC transporter E3160_08895 ENOG4105F1S paraquat-inducible protein a E3160_08900 ENOG4105DY2 Paraquat-inducible protein b E3160_08905 ENOG4108Q2G (LipO)protein E3160_08910 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) E3160_08920 ENOG4105DAN ATP-dependent protease E3160_08930 ENOG4105UYK outer membrane protein a E3160_08940 ENOG4108RZ1 DNA transformation protein E3160_08945 ENOG4105EM2 membrane E3160_08950 ENOG410901E Membrane E3160_08955 ENOG41088T4 Helicase IV E3160_08970 ENOG4105K4P CoA-binding domain protein E3160_08985 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 E3160_08990 ENOG4108Z0T Part of a sulfur-relay system (By similarity) E3160_08995 ENOG4108MN8 Membrane E3160_09020 ENOG4106G8A Qin prophage E3160_09085 ENOG4105JBR DNA replication protein E3160_09125 ENOG4108MXB Protein of unknown function (DUF968) E3160_09130 ENOG4105KSK (crossover) junction endodeoxyribonuclease E3160_09135 ENOG4105HRS Antitermination protein E3160_09175 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_09205 ENOG4105UZW Tail fiber assembly protein E3160_09230 ENOG4105IM0 capsid protein E3160_09290 ENOG4108X9F tail fiber protein E3160_09315 ENOG4105E3S small subunit E3160_09320 ENOG4105DPX Hydrogenase, large subunit E3160_09325 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit E3160_09330 ENOG4108USZ hydrogenase E3160_09335 ENOG4108VXY Hydrogenase-1 operon protein HyaE E3160_09340 ENOG4105MVP hydrogenase-1 operon protein HyaF E3160_09345 ENOG4105C4M (Ubiquinol oxidase) subunit I E3160_09350 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E3160_09360 ENOG4105D6F Phosphatase E3160_09365 ENOG4108F2G Chain length determinant protein E3160_09370 ENOG4107ZF2 Phosphatase E3160_09375 ENOG4105DAY polysaccharide export protein E3160_09380 ENOG4105E3R (LipO)protein E3160_09385 ENOG4108W78 Pfam:DUF1017 E3160_09390 ENOG4108Y9B (LipO)protein E3160_09400 ENOG41060EU Cold shock-like protein E3160_09405 ENOG4105VEQ Cold shock protein E3160_09425 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation E3160_09430 ENOG4105HEE Binding Domain protein E3160_09435 ENOG4105BZU Histidine kinase E3160_09440 ENOG4108SV3 Tmao reductase system periplasmic protein tort E3160_09445 ENOG4106WF9 DNA-binding transcriptional regulator TorR E3160_09450 ENOG4105CUW cytochrome C-TYPE protein E3160_09455 ENOG4108J2R molybdopterin oxidoreductase E3160_09480 ENOG4105D6F Phosphatase E3160_09485 ENOG4105XH3 E3160_09495 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 E3160_09500 ENOG4105C2W permease E3160_09540 ENOG4108R86 Transcriptional regulator E3160_09545 ENOG4105C26 Dehydrogenase E3160_09555 ENOG4105CK7 Sodium proline symporter E3160_09570 ENOG410650H (LipO)protein E3160_09575 ENOG4105DBE peroxidase E3160_09580 ENOG4105D5M phosphate starvation-inducible protein E3160_09590 ENOG4105CND Glycosyl transferase, family 2 E3160_09595 ENOG4107BJW polysaccharide deacetylase E3160_09600 ENOG4108TUY outer membrane protein PgaA E3160_09605 ENOG4105BZU Histidine kinase E3160_09610 ENOG4105CXC rtn protein E3160_09620 ENOG4108TC1 Transcriptional regulator E3160_09625 ENOG4105CHR reductase E3160_09630 ENOG4108MQF Chaperone E3160_09645 ENOG4108AF8 Chaperone E3160_09650 ENOG4105X0I Fimbrial E3160_09660 ENOG4105CKT filamentous hemagglutinin E3160_09665 ENOG4105D5K Hemolysin activator protein E3160_09670 ENOG41081XD Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) E3160_09680 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) E3160_09690 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) E3160_09695 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3160_09740 ENOG4108T85 Membrane E3160_09745 ENOG4105DFP Integrase E3160_09775 ENOG4108P8R E3160_09820 ENOG4108YXQ IS66 Orf2 family protein E3160_09855 ENOG41080IJ Diacylglycerol kinase E3160_09860 ENOG4105DIJ Phosphoethanolamine transferase E3160_09870 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) E3160_09915 ENOG4105NRA 50s ribosomal protein l31 type b E3160_09965 ENOG4108YXQ IS66 Orf2 family protein E3160_09970 ENOG4105E5H Transposase E3160_10005 ENOG4105DAX Pfam:DUF2983 E3160_10055 ENOG410836F Transposase E3160_10070 ENOG4105D05 Receptor E3160_10170 ENOG4105D5K Hemolysin activator protein E3160_10190 ENOG4105F4K antigen 43 E3160_10195 ENOG4108F5E vimentin E3160_10200 ENOG4108YIV E3160_10215 ENOG4106H6R UPF0380 protein E3160_10220 ENOG4106549 Antirestriction protein E3160_10225 ENOG4108YGG dna repair protein E3160_10235 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E3160_10275 ENOG4107XHZ cytoplasmic chaperone TorD family protein E3160_10280 ENOG4108UQ5 membrane protein YcdZ E3160_10290 ENOG4105E5H Transposase E3160_10295 ENOG4108YXQ IS66 Orf2 family protein E3160_10310 ENOG4108WYR Curli production assembly transport component, CsgF E3160_10315 ENOG4108XDW curli assembly protein CsgE E3160_10320 ENOG41086KC Transcriptional regulator E3160_10325 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers E3160_10330 ENOG41090QH cryptic curlin major subunit E3160_10345 ENOG4108UVJ appr-1-p processing domain protein E3160_10350 ENOG4107RZC phospholipase d E3160_10365 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) E3160_10370 ENOG4105NAC (LipO)protein E3160_10375 ENOG4108W47 Acidic protein msyB E3160_10385 ENOG4105D1S lipid A biosynthesis E3160_10395 ENOG4108YYC ycei family E3160_10400 ENOG4105DS1 cytochrome b561 E3160_10405 ENOG4106974 biofilm formation E3160_10415 ENOG4105PVA Biofilm formation regulatory protein BssS E3160_10420 ENOG4105MEA DNA damage-inducible protein i E3160_10430 ENOG4105F3T (LipO)protein E3160_10435 ENOG4105E9S glutaredoxin 2 E3160_10445 ENOG4105D9U N-acetyltransferase E3160_10455 ENOG4105EP9 oxidoreductase E3160_10460 ENOG4105CJR Integral membrane protein (MviN E3160_10465 ENOG4105QVD Flagella synthesis protein FlgN E3160_10470 ENOG4105M9M anti-sigma28 factor FlgM E3160_10475 ENOG4105CKS Flagella basal body P-ring formation protein flgA E3160_10480 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) E3160_10485 ENOG4108ZC9 flagellar basal-body rod protein flgc E3160_10490 ENOG4105W00 Flagellar hook capping protein E3160_10495 ENOG4105BZE flagellar hook protein, FlgE E3160_10500 ENOG4108KPB Flagellar basal-body rod protein FlgF E3160_10505 ENOG4105CGA flagellar basal-body rod protein FlgG E3160_10520 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj E3160_10525 ENOG4105E1Q flagellar hook-associated protein E3160_10530 ENOG4105DTJ flagellar hook-associated protein E3160_10535 ENOG4107QQB Ribonuclease E E3160_10540 ENOG41071G1 Uncharacterized protein YceQ E3160_10545 ENOG4105EI2 Pseudouridine synthase E3160_10550 ENOG4108UHJ MAF-like protein E3160_10555 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein E3160_10575 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase E3160_10580 ENOG4105CHR reductase E3160_10585 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E3160_10590 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3160_10595 ENOG4105YAZ 4-amino-4-deoxychorismate lyase E3160_10600 ENOG4105HHA aminodeoxychorismate lyase E3160_10610 ENOG4107QRG dna polymerase iii E3160_10615 ENOG4105F8V Hydrolase, tatD family E3160_10620 ENOG4105CI1 PTS System E3160_10625 ENOG4105CNM Receptor E3160_10635 ENOG4105K59 histidine triad (HIT) protein E3160_10640 ENOG41090DQ Lipoprotein E3160_10645 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) E3160_10650 ENOG4108RUM thiamine kinase E3160_10665 ENOG4105CEP NADH dehydrogenase E3160_10670 ENOG4107MBR 17 kDa surface antigen E3160_10675 ENOG4108IND Tetr family transcriptional regulator E3160_10680 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction E3160_10685 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3160_10690 ENOG4108JA2 transcriptioN-repair coupling factor E3160_10700 ENOG4105D60 lipoprotein releasing system transmembrane protein E3160_10705 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) E3160_10710 ENOG4105D60 lipoprotein releasing system transmembrane protein E3160_10720 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) E3160_10725 ENOG4107RUE extracellular solute-binding protein family 1 E3160_10730 ENOG4105D38 putrescine abc transporter E3160_10735 ENOG4108I1J Integrase E3160_10765 ENOG4108X9F tail fiber protein E3160_10835 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3160_10845 ENOG4105EZE Cupin 4 family protein E3160_10945 ENOG4105CAR Terminase, large subunit E3160_10960 ENOG4105IFJ Histidine kinase E3160_10965 ENOG4105XJC Two component transcriptional regulator (Winged helix family E3160_10970 ENOG4107QTF adenylosuccinate lyase E3160_10980 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) E3160_10990 ENOG4108R99 pseudouridine synthase E3160_10995 ENOG4108HMX isocitrate dehydrogenase (NADP) E3160_11000 ENOG4108I1J Integrase E3160_11040 ENOG4105QYK bacteriophage lambda Bor protein homolog E3160_11055 ENOG4106YSC E3160_11060 ENOG4105FKG DNA packaging protein E3160_11065 ENOG4105UZW Tail fiber assembly protein E3160_11070 ENOG4107DE1 head-to-tail joining protein E3160_11080 ENOG4105F7J membrane-bound serine protease E3160_11090 ENOG4105IM0 capsid protein E3160_11170 ENOG4105UZW Tail fiber assembly protein E3160_11175 ENOG4105WEF catalase E3160_11180 ENOG4108N8X transition metal ion binding E3160_11185 ENOG4108Z9Z response to DNA damage stimulus E3160_11200 ENOG4108WF3 methyltransferase E3160_11215 ENOG4108YXQ IS66 Orf2 family protein E3160_11220 ENOG4105E5H Transposase E3160_11240 ENOG4108NC2 Outer membrane protease E3160_11250 ENOG4105K5X acetyltransferase E3160_11255 ENOG4108HMX isocitrate dehydrogenase (NADP) E3160_11270 ENOG41064WM Uncharacterized protein YcgX E3160_11275 ENOG4108XDN Transcriptional regulator E3160_11280 ENOG4105BZU Histidine kinase E3160_11285 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component E3160_11290 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB E3160_11300 ENOG410738I uncharacterized protein ymgC E3160_11305 ENOG4105BZU Histidine kinase E3160_11320 ENOG410658X E3160_11360 ENOG4107QMS site-determining protein E3160_11370 ENOG4105S66 prophage protein E3160_11375 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium E3160_11385 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase E3160_11395 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells E3160_11400 ENOG4105KT5 UmuD protein E3160_11405 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E3160_11410 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) E3160_11425 ENOG4105ED1 spovr family E3160_11435 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E3160_11460 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A E3160_11470 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) E3160_11485 ENOG4108PQF modD protein E3160_11490 ENOG4108BSC Methyltransferase E3160_11495 ENOG4105E0A ABC, transporter E3160_11500 ENOG4105EHG Permease protein E3160_11505 ENOG4105S10 periplasmic binding protein E3160_11515 ENOG4105E53 ec 3.2.1.28 E3160_11525 ENOG4105VDH Dihydroxyacetone kinase E3160_11530 ENOG4108UTZ Dihydroxyacetone kinase E3160_11535 ENOG4105CMT Dihydroxyacetone kinase E3160_11540 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family E3160_11560 ENOG4105C3G gtp-binding protein E3160_11570 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria E3160_11575 ENOG4105CHH sulfate transporter E3160_11580 ENOG4105C5T Phosphoribosyl pyrophosphate synthase E3160_11585 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) E3160_11595 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) E3160_11610 ENOG4108YY7 Invasion gene expression up-regulator SirB E3160_11615 ENOG41063JG Transcriptional regulator E3160_11635 ENOG4105EWV Sodium calcium exchanger membrane region E3160_11640 ENOG4105WS7 Cation transport regulator E3160_11645 ENOG4108NH8 Cation transport protein E3160_11650 ENOG41090EX DsrE family E3160_11655 ENOG4105ID0 Putative invasin E3160_11660 ENOG4105WH1 Two component transcriptional regulator luxr family E3160_11665 ENOG4105BZU Histidine kinase E3160_11670 ENOG4105DQQ Major facilitator superfamily MFS_1 E3160_11675 ENOG4105CRU nitrate reductase, alpha subunit E3160_11680 ENOG4108IUE nitrate reductase beta subunit E3160_11685 ENOG4105R3A Nitrate reductase E3160_11690 ENOG41076YT nitrate reductase, gamma subunit E3160_11720 ENOG4105CIY formyltetrahydrofolate deformylase E3160_11730 ENOG4105D78 K07001 NTE family protein E3160_11735 ENOG4105I93 response regulator E3160_11740 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E3160_11745 ENOG4108SAU DNA-binding protein H-ns E3160_11750 ENOG4107104 thymidine kinase E3160_11755 ENOG4105C0A alcohol dehydrogenase E3160_11760 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein E3160_11765 ENOG4108J59 Extracellular solute-binding protein, family 5 E3160_11770 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3160_11775 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3160_11780 ENOG4105C3U ABC transporter E3160_11785 ENOG4108JQ7 (ABC) transporter E3160_11805 ENOG4107SVH Potassium channel protein E3160_11810 ENOG4105K9H YciI-like protein E3160_11815 ENOG410822N TonB family E3160_11820 ENOG4105NAU thioesterase Superfamily protein E3160_11830 ENOG4108S3I UPF0259 membrane protein E3160_11840 ENOG4105EIF outer membrane protein W E3160_11845 ENOG4108N8X transition metal ion binding E3160_11850 ENOG4108Z9Z response to DNA damage stimulus E3160_11870 ENOG4105DK0 Indole-3-glycerol phosphate synthase E3160_11875 ENOG4108EFP Anthranilate synthase component II E3160_11880 ENOG4105CRQ synthase (Component I) E3160_11890 ENOG4105DB7 PHP domain protein E3160_11895 ENOG4107RTD sua5 ycio yrdc ywlc family protein E3160_11900 ENOG4105EG3 transmembrane signal peptide protein E3160_11905 ENOG4105FE9 pseudouridine synthase E3160_11910 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase E3160_11915 ENOG4105UBK short-chain dehydrogenase reductase E3160_11920 ENOG4105ERU peptidase E3160_11925 ENOG4105RKX Protein of unknown function (DUF2498) E3160_11930 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E3160_11935 ENOG4107R11 Transcriptional regulator E3160_11955 ENOG4107QM5 aconitate hydratase E3160_11965 ENOG4105EYK Phosphatidylglycerophosphatase B E3160_11970 ENOG4105Q4A inner membrane protein yciS E3160_11975 ENOG4105CFV Tetratricopeptide repeat protein E3160_11985 ENOG4108ZJT translation initiation factor, Sui1 E3160_11995 ENOG4105N2W Transcriptional regulator E3160_12000 ENOG410643D UPF0509 protein E3160_12005 ENOG4105BZU Histidine kinase E3160_12015 ENOG4105Q4T oxidoreductase E3160_12020 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH E3160_12025 ENOG41067SE Tetr family transcriptional regulator E3160_12030 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3160_12035 ENOG4105BZS acriflavin resistance protein E3160_12040 ENOG4105ENJ RND efflux system, outer membrane lipoprotein E3160_12045 ENOG4105C2C drug resistance transporter, Bcr CflA E3160_12050 ENOG4108JQ2 peptide transport system atp-binding protein E3160_12055 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein E3160_12060 ENOG4108EU3 peptide transport system, permease E3160_12065 ENOG4108I5W peptide transport system, permease protein E3160_12070 ENOG4108HIY periplasmic E3160_12075 ENOG4105N0E Protein of unknown function (DUF2543) E3160_12080 ENOG4105CUB amino acid E3160_12090 ENOG4105CFQ glutamine synthetase E3160_12095 ENOG4108Z86 Glutamine amidotransferase E3160_12100 ENOG4107VRI Transcriptional regulator E3160_12105 ENOG4105C26 Dehydrogenase E3160_12110 ENOG4105CJP fad dependent oxidoreductase E3160_12115 ENOG4108JPW Aminotransferase E3160_12120 ENOG4105E51 psp operon transcriptional activator E3160_12125 ENOG41087YS Phage shock protein A E3160_12130 ENOG4105YYT phage shock protein B E3160_12135 ENOG4105FM1 phage shock protein C E3160_12140 ENOG4105NNG Peripheral inner membrane phage-shock protein E3160_12145 ENOG4105K8Z Phage shock protein E3160_12150 ENOG4107QW3 Sucrose phosphorylase E3160_12155 ENOG4107QW3 Sucrose phosphorylase E3160_12165 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component E3160_12170 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component E3160_12175 ENOG4107RRD Dehydrogenase E3160_12180 ENOG4107TYA transient receptor potential locus E3160_12185 ENOG4105CK5 oxidoreductase E3160_12190 ENOG4105C71 hydrolase family 65, central catalytic E3160_12195 ENOG4107URF beta-phospho-glucomutase E3160_12200 ENOG4108IJ9 (ABC) transporter E3160_12205 ENOG4107EFV Outer membrane protein G E3160_12210 ENOG4105FKQ transcriptional regulator E3160_12215 ENOG4105CM6 amino acid regulated cytosolic protein E3160_12225 ENOG4108JU8 Transcriptional regulator E3160_12230 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) E3160_12235 ENOG4107S8C mandelate racemase muconate lactonizing E3160_12240 ENOG4105KXI murein peptide amidase A E3160_12265 ENOG4105ENX hydrolase E3160_12270 ENOG4105EQ2 LysR family Transcriptional regulator E3160_12275 ENOG4107QSI ABC, transporter E3160_12280 ENOG4105D64 Mechanosensitive ion channel E3160_12285 ENOG4105S5I Membrane E3160_12290 ENOG4105Q9Y Universal stress protein E3160_12295 ENOG4105DS0 Transcriptional regulator, Crp Fnr family E3160_12300 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E3160_12305 ENOG4105CFC Transporter E3160_12310 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B E3160_12315 ENOG4105CH2 amidohydrolase E3160_12320 ENOG4106KR7 LysR family Transcriptional regulator E3160_12325 ENOG4108DG9 Smr protein MutS2 E3160_12330 ENOG4105BZU Histidine kinase E3160_12345 ENOG4105C1J atp-dependent rna helicase E3160_12355 ENOG4107R08 Integrase E3160_12360 ENOG4107160 Rac prophage E3160_12365 ENOG41070YT Rac prophage E3160_12375 ENOG4108PNI recT protein E3160_12400 ENOG4107C82 Rac prophage E3160_12410 ENOG4106050 phage regulatory protein, rha family E3160_12455 ENOG4105JBR DNA replication protein E3160_12500 ENOG4105RWQ Protein of unknown function (DUF1364) E3160_12540 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_12580 ENOG4105DFP Integrase E3160_12640 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) E3160_12665 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) E3160_12735 ENOG4105H38 Membrane E3160_12740 ENOG4108X9F tail fiber protein E3160_12765 ENOG4108RW8 Universal stress protein F E3160_12770 ENOG4105FCK Membrane E3160_12775 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) E3160_12780 ENOG4105IKK cytoplasmic protein E3160_12785 ENOG41090X5 Heat shock protein hslJ E3160_12790 ENOG4105C5I Dehydrogenase E3160_12795 ENOG4107H52 Dicarboxylate transport E3160_12800 ENOG410689M (LipO)protein E3160_12805 ENOG4105WXT Conserved Protein E3160_12815 ENOG4107EF2 surface-exposed virulence protein E3160_12820 ENOG4107S5I aldo keto reductase E3160_12830 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase E3160_12835 ENOG4108HPI phosphatidate Cytidylyltransferase E3160_12840 ENOG4105E8V Alpha Beta Hydrolase Fold protein E3160_12845 ENOG41077RS Phosphatase E3160_12850 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) E3160_12855 ENOG4105CQ7 ATP-dependent helicase E3160_12880 ENOG4107DB1 DUF218 domain E3160_12885 ENOG4105C26 Dehydrogenase E3160_12890 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E3160_12895 ENOG4105CPW cytochrome b561 E3160_12900 ENOG4105UPP uncharacterized protein ydcA E3160_12905 ENOG4107NK6 Hok/gef family E3160_12915 ENOG4105C8Q Methyl-accepting chemotaxis E3160_12920 ENOG4105DDW LysR family Transcriptional regulator E3160_12925 ENOG4105E32 cytoplasmic protein E3160_12935 ENOG4105Z2P Protein of unknown function (DUF465) E3160_12940 ENOG4108Z9I -acetyltransferase E3160_12945 ENOG4107WE3 acetyltransferase YdcK E3160_12950 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein E3160_12955 ENOG41088CC tellurite resistance protein tehB E3160_12960 ENOG4108KKZ (LipO)protein E3160_12965 ENOG4105DKK Benzoate E3160_12970 ENOG4108JCI Transcriptional regulator E3160_12975 ENOG4105CFP Peptidase U32 E3160_12980 ENOG4105RR0 Protein of unknown function (DUF2554) E3160_12990 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin E3160_12995 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E3160_13000 ENOG4107TYH extracellular solute-binding protein family 1 E3160_13005 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3160_13010 ENOG4105D81 ABC transporter, permease E3160_13015 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component E3160_13030 ENOG410654E Membrane E3160_13035 ENOG4105R71 cytoplasmic protein E3160_13040 ENOG4108T9Y Inner membrane protein ydcZ E3160_13045 ENOG4108Z7F N-acetyltransferase E3160_13050 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein E3160_13055 ENOG4108WYP Transcriptional regulator E3160_13060 ENOG4105CHB tonB-dependent Receptor E3160_13065 ENOG4108NS2 receptor E3160_13070 ENOG4105C85 amino acid E3160_13075 ENOG4108N27 Glutathione S-transferase E3160_13085 ENOG4105CS6 Rhs element vgr protein E3160_13090 ENOG4105CNA YD repeat protein E3160_13120 ENOG4108MEJ flavin reductase domain protein E3160_13125 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase E3160_13130 ENOG4105JAB phenazine biosynthesis protein, phzf family E3160_13135 ENOG4105D0D Nitrate reductase 2, gamma subunit E3160_13140 ENOG4108NZN Respiratory nitrate reductase 2 delta chain E3160_13145 ENOG4108IUE nitrate reductase beta subunit E3160_13150 ENOG4105CRU nitrate reductase, alpha subunit E3160_13155 ENOG4107QND Nitrite extrusion protein E3160_13165 ENOG4108UI3 Leucine Rich repeat E3160_13180 ENOG4105RPH Inner membrane protein YddG E3160_13185 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) E3160_13190 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) E3160_13195 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3160_13200 ENOG4108MG3 formate dehydrogenase E3160_13205 ENOG41084S7 Plasmid maintenance system antidote protein E3160_13210 ENOG4105DQ4 alcohol dehydrogenase E3160_13220 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein E3160_13225 ENOG4105TPS biofilm-dependent modulation protein E3160_13230 ENOG4108Z9K Osmotically inducible protein E3160_13235 ENOG4107H6U ABC transporter E3160_13240 ENOG4105C3U ABC transporter E3160_13245 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3160_13250 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3160_13260 ENOG4108UQS dipeptidase E3160_13265 ENOG4105BZU Histidine kinase E3160_13270 ENOG4105BZU Histidine kinase E3160_13275 ENOG4105F32 YngK protein E3160_13280 ENOG4105E5D amino acid E3160_13285 ENOG4105CVK Glutamate decarboxylase E3160_13290 ENOG4107RAN Peptidase, M16 E3160_13295 ENOG4105PE1 Receptor E3160_13300 ENOG4105CQ0 ABC transporter E3160_13310 ENOG4105C4X radical SAM domain protein E3160_13315 ENOG4105ENH Sulfatase E3160_13320 ENOG4108NKV transcriptional regulator E3160_13330 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit E3160_13335 ENOG4106PIH fimbrial-like protein ydeQ E3160_13340 ENOG4106318 fimbrial-like protein YdeR E3160_13345 ENOG4108WDE Fimbrial protein E3160_13350 ENOG4105CW0 outer membrane usher protein E3160_13360 ENOG4108RQP Major type 1 subunit fimbrin E3160_13375 ENOG4105CAF HipA N-terminal domain protein E3160_13380 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein E3160_13395 ENOG4107RYS Autoinducer-2 (AI-2) kinase E3160_13405 ENOG4105C2J ABC transporter E3160_13410 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane E3160_13415 ENOG4105F5R ABC transporter E3160_13425 ENOG41061GT Aldolase E3160_13430 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound E3160_13440 ENOG4105FFC UPF0187 protein E3160_13450 ENOG4105BZU Histidine kinase E3160_13455 ENOG4105M0C cytoplasmic protein E3160_13460 ENOG4105CSV Glutaminase E3160_13465 ENOG4105C26 Dehydrogenase E3160_13470 ENOG4105EGI Transcriptional regulator E3160_13485 ENOG4105F27 Major Facilitator E3160_13495 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes E3160_13500 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF E3160_13505 ENOG4106DNR multiple antibiotic resistance protein E3160_13510 ENOG4108594 Permease of the drug metabolite transporter E3160_13515 ENOG4105E5W Transporter E3160_13535 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria E3160_13540 ENOG4108YDI single-species biofilm formation on inanimate substrate E3160_13545 ENOG4108WTK competence damage-inducible protein E3160_13550 ENOG4105DGW oligopeptidase A E3160_13555 ENOG4105EMU Dehydrogenase E3160_13560 ENOG4107XBN GntR Family Transcriptional Regulator E3160_13565 ENOG41061EV selenium-binding protein YdfZ E3160_13570 ENOG4105DEI Mannitol dehydrogenase E3160_13585 ENOG4105D5G Transposase E3160_13680 ENOG4106YSC E3160_13725 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_13775 ENOG4105KSK (crossover) junction endodeoxyribonuclease E3160_13780 ENOG4108MXB Protein of unknown function (DUF968) E3160_13795 ENOG4105WI6 cell killing protein encoded within cryptic prophage E3160_13845 ENOG41087BU transcriptional repressor DicA E3160_13885 ENOG4106G8A Qin prophage E3160_13900 ENOG4108I1J Integrase E3160_13955 ENOG4108YXQ IS66 Orf2 family protein E3160_13960 ENOG4105E5H Transposase E3160_13970 ENOG4106N4H Non-LEE-encoded type III effector F E3160_14010 ENOG4108X9F tail fiber protein E3160_14120 ENOG4106YSC E3160_14155 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_14200 ENOG4105KSK (crossover) junction endodeoxyribonuclease E3160_14205 ENOG4108MXB Protein of unknown function (DUF968) E3160_14215 ENOG4105WI6 cell killing protein encoded within cryptic prophage E3160_14240 ENOG4105JBR DNA replication protein E3160_14295 ENOG4106G8A Qin prophage E3160_14430 ENOG4105IM0 capsid protein E3160_14440 ENOG4105F7J membrane-bound serine protease E3160_14450 ENOG4107DE1 head-to-tail joining protein E3160_14455 ENOG4105UZW Tail fiber assembly protein E3160_14460 ENOG4105FKG DNA packaging protein E3160_14470 ENOG4106YSC E3160_14505 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_14550 ENOG4105KSK (crossover) junction endodeoxyribonuclease E3160_14555 ENOG4108MXB Protein of unknown function (DUF968) E3160_14565 ENOG4105H4F exported protein E3160_14570 ENOG4105WI6 cell killing protein encoded within cryptic prophage E3160_14600 ENOG4107R08 Integrase E3160_14610 ENOG4105CPQ Dehydrogenase E3160_14615 ENOG4105CXK mandelate racemase muconate lactonizing E3160_14630 ENOG4108MK9 spermidine N(1)-acetyltransferase E3160_14635 ENOG4105D69 UPF0257 lipoprotein ynfC E3160_14640 ENOG4105KBG Protein of unknown function (DUF1161) E3160_14645 ENOG4107QY8 reductase E3160_14650 ENOG4105C3J Cysteine desulfurase E3160_14655 ENOG4105QAX Iron-sulfur E3160_14660 ENOG4107KGK dmso reductase anchor subunit E3160_14665 ENOG4108NEM leader-binding protein dmsD E3160_14675 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E3160_14680 ENOG4105DAG ROK family E3160_14685 ENOG4106NZI LysR family Transcriptional regulator E3160_14690 ENOG4105D94 Major Facilitator Superfamily E3160_14705 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap E3160_14725 ENOG4105DSF transport protein E3160_14730 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E3160_14735 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E3160_14740 ENOG4105C5D exported protein E3160_14745 ENOG4105D5Q Arginine ornithine antiporter E3160_14755 ENOG4105RA2 Membrane E3160_14760 ENOG4107EXC regulatoR E3160_14765 ENOG4105JJR Histidine kinase E3160_14770 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) E3160_14775 ENOG4105C9Q fumarate hydratase class II E3160_14780 ENOG4107GFK fumarate E3160_14785 ENOG4105EIP mannose-6-phosphate isomerase E3160_14790 ENOG4106J39 exported protein E3160_14800 ENOG4105CT4 transporter E3160_14805 ENOG4105CNT hydrolase family 2 E3160_14810 ENOG4105XEA Tetr family transcriptional regulator E3160_14815 ENOG4107ZQV short-chain dehydrogenase reductase E3160_14820 ENOG4107P2S Transcriptional regulator E3160_14825 ENOG4105CI1 PTS System E3160_14830 ENOG4105C87 Aminotransferase class I and II E3160_14840 ENOG4105D9R oxidoreductase E3160_14845 ENOG4106C6R beta-lactam resistance protein E3160_14850 ENOG4105QZ5 OriC-binding nucleoid-associated protein E3160_14855 ENOG4105M9B inner membrane protein ydgK E3160_14880 ENOG4108UQQ Electron transport complex E3160_14890 ENOG4105CSM endonuclease III E3160_14895 ENOG4105DUX Transporter E3160_14900 ENOG4108K3A Glutathione S-transferase E3160_14905 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) E3160_14920 ENOG410642K Lysozyme inhibitor E3160_14930 ENOG4108XTF Outer Membrane Lipoprotein E3160_14945 ENOG4105Y49 secretion protein, HlyD family E3160_14950 ENOG4105DSW Fusaric acid resistance protein E3160_14955 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3160_14960 ENOG4107RGM aldo keto reductase E3160_14965 ENOG4105XZD Fe-S protein E3160_14970 ENOG4108WUH Transcriptional regulator, TetR family E3160_14975 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E3160_14980 ENOG4108UYE Lactoylglutathione lyase E3160_14990 ENOG4107QRT dEAD DEAH box helicase E3160_14995 ENOG4105M2J Glutaredoxin E3160_15000 ENOG4105K4H Nlp p60 protein E3160_15005 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3160_15010 ENOG4105F27 Major Facilitator E3160_15025 ENOG4105F52 Transcriptional regulator E3160_15030 ENOG4105CZQ inner membrane transport protein YdhC E3160_15035 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase E3160_15040 ENOG4108R6K riboflavin synthase, subunit alpha E3160_15045 ENOG4107QI1 Mate efflux family protein E3160_15070 ENOG4105N0V mono-oxygenase ydhR E3160_15075 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain E3160_15085 ENOG4108NWD Cytochrome E3160_15090 ENOG4108393 oxidoreductase Fe-S subunit E3160_15100 ENOG4105WE2 aldehyde ferredoxin oxidoreductase E3160_15105 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein E3160_15110 ENOG4105RFR Protein of unknown function (DUF2767) E3160_15115 ENOG4105CA9 Pyruvate kinase E3160_15120 ENOG4105KMX major outer membrane lipoprotein E3160_15125 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3160_15140 ENOG4105JRK feS assembly protein SufD E3160_15145 ENOG4105C3K feS assembly ATPase SufC E3160_15150 ENOG4105DIW FeS assembly protein SUFB E3160_15155 ENOG4108Z4V iron-sulfur cluster assembly E3160_15160 ENOG410671Z uncharacterized protein ydiH E3160_15165 ENOG4105KA0 thioesterase Superfamily protein E3160_15170 ENOG4105CQB FAD linked oxidase domain protein E3160_15175 ENOG4105IPI Membrane E3160_15185 ENOG4105SUA Ydil protein E3160_15190 ENOG4105EMV Major Facilitator E3160_15195 ENOG4105EMV Major Facilitator E3160_15210 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) E3160_15215 ENOG4105C1G acyl-Coa dehydrogenase E3160_15220 ENOG4105W4W Transcriptional regulator E3160_15225 ENOG4105CV7 Electron transfer flavoprotein E3160_15230 ENOG4105C10 Electron transfer flavoprotein E3160_15235 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3160_15240 ENOG41090P5 ferredoxin-like protein E3160_15245 ENOG4105CEY Amp-dependent synthetase and ligase E3160_15250 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) E3160_15260 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3160_15275 ENOG4108TC0 Diguanylate phosphodiesterase E3160_15280 ENOG4108QBX (LipO)protein E3160_15290 ENOG4108V06 Glutathione peroxidase E3160_15305 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) E3160_15325 ENOG41082NX 50s ribosomal protein l35 E3160_15330 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) E3160_15350 ENOG4108NE3 Salt-induced outer membrane protein E3160_15355 ENOG4105DE4 1-phosphofructokinase E3160_15360 ENOG4105P10 Uncharacterized protein ydiZ E3160_15370 ENOG4107PN8 YfeABCD locus regulator E3160_15375 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 E3160_15380 ENOG4107K5X Membrane-bound metal-dependent hydrolase E3160_15385 ENOG4108ETY sodium dicarboxylate symporter E3160_15400 ENOG4105CH6 catalase E3160_15410 ENOG4105F8D glycoside hydrolase family 4 E3160_15415 ENOG4105EZV Transcriptional regulator E3160_15420 ENOG4105VCP PTS System E3160_15425 ENOG4105CK1 PTS System E3160_15430 ENOG4105VZJ PTS System E3160_15440 ENOG4105KKI DNA-binding transcriptional activator OsmE E3160_15450 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) E3160_15460 ENOG4108SPG Periplasmic Protein E3160_15490 ENOG4105CGK Exodeoxyribonuclease III E3160_15495 ENOG4108RSN SNARE associated Golgi E3160_15500 ENOG4108KCW iron-sulfur cluster binding E3160_15505 ENOG4108N5C SNARE associated Golgi protein-related protein E3160_15510 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E3160_15515 ENOG4105VNH ABC transporter solute-binding protein E3160_15520 ENOG4105CXZ ABC transporter, permease E3160_15525 ENOG4108VGW abc transporter atp-binding protein E3160_15530 ENOG4107RM6 sulfurtransferase E3160_15535 ENOG4108T9J Cdp-alcohol phosphatidyltransferase E3160_15540 ENOG4105M6F mutator MutT protein E3160_15545 ENOG4105MTM Protein of unknown function (DUF1496) E3160_15550 ENOG4105D82 Glutamate dehydrogenase E3160_15555 ENOG41065FB inner membrane protein ynji E3160_15560 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E3160_15565 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) E3160_15570 ENOG41069NU Nitroreductase E3160_15575 ENOG4105D07 Signal peptide peptidase, SppA E3160_15585 ENOG4105HDK L-asparaginase E3160_15590 ENOG4108RWI nicotinamidase E3160_15595 ENOG4108KUU Inner membrane metabolite transport protein ydjE E3160_15600 ENOG4105E98 transcriptional regulator DeoR family E3160_15605 ENOG4105CPC Aldo Keto reductase E3160_15610 ENOG4107UH8 sugar kinase E3160_15615 ENOG4105D2N Aldolase E3160_15620 ENOG4105CPQ Dehydrogenase E3160_15625 ENOG4107TE1 transport protein E3160_15630 ENOG4105CPQ Dehydrogenase E3160_15635 ENOG4105VUT cytoplasmic protein E3160_15645 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E3160_15650 ENOG4105DSB aldose 1-epimerase E3160_15655 ENOG4105CV8 reductase E3160_15660 ENOG4105GNX MltA-interacting MipA family protein E3160_15665 ENOG4105CYN Serine protein kinase E3160_15675 ENOG4106KTS Inner membrane protein yeaI E3160_15680 ENOG4108KHP Diguanylate cyclase E3160_15685 ENOG4108KXH Ybak prolyl-tRNA synthetase associated E3160_15700 ENOG4105R1U AraC Family Transcriptional Regulator E3160_15705 ENOG4105DJ2 Major Facilitator Superfamily E3160_15710 ENOG4105K78 MarR family Transcriptional regulator E3160_15715 ENOG4105UCG Domain of unknown function (DUF333) E3160_15720 ENOG410620I Diguanylate cyclase E3160_15725 ENOG4106G4W E3160_15735 ENOG4105Y3U Transglycosylase-associated protein E3160_15740 ENOG4105YP6 Domain of unknown function (DUF1869) E3160_15745 ENOG4108YS1 cytoplasmic protein E3160_15750 ENOG4108NIW Leucine export protein LeuE E3160_15755 ENOG4105EJC lysr family transcriptional regulator E3160_15760 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) E3160_15765 ENOG4105C94 Transporter E3160_15770 ENOG4105DVW rieske (2Fe-2S) E3160_15775 ENOG4105E3J oxidoreductase E3160_15780 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) E3160_15785 ENOG4105CEY Amp-dependent synthetase and ligase E3160_15790 ENOG4105Y4Z Outer Membrane Lipoprotein E3160_15795 ENOG41072GX Peptidase M22 Glycoprotease E3160_15800 ENOG4105DVT helicase E3160_15805 ENOG4105M4H endoribonuclease L-psp E3160_15810 ENOG4105V2F Uncharacterized protein yoac E3160_15820 ENOG4105CRQ synthase (Component I) E3160_15830 ENOG4105EJQ L-serine dehydratase E3160_15835 ENOG4107XTP (EAL) domain protein E3160_15840 ENOG4105EE5 Membrane protein terC E3160_15845 ENOG4105DAS pts system E3160_15850 ENOG4105ETZ PTS System E3160_15855 ENOG4105F3R pts system mannose fructose sorbose family iid E3160_15870 ENOG4105DHI Methyltransferase E3160_15885 ENOG4105Q3Y exported protein E3160_15895 ENOG4105TIK E3160_15900 ENOG4105J4Q Transcriptional regulator E3160_15905 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3160_15915 ENOG4105CN1 protease E3160_15925 ENOG4108ZGC gaf domain protein E3160_15930 ENOG4105H2K paraquat-inducible protein a E3160_15935 ENOG4105DY2 Paraquat-inducible protein b E3160_15945 ENOG4105WT8 Protein of unknown function (DUF1480) E3160_15950 ENOG4105UVW uncharacterized protein yebW E3160_15955 ENOG4108R1E Serine threonine protein phosphatase 1 E3160_15960 ENOG4105NKT exported protein E3160_15965 ENOG4108PNC copper resistance E3160_15970 ENOG4105FXM Copper resistance protein E3160_15975 ENOG4105MPK DNA polymerase III subunit theta E3160_15980 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E3160_15985 ENOG4105UMD exodeoxyribonuclease X E3160_15990 ENOG4105CUG Oligopeptidase b E3160_15995 ENOG4108Q2J Inner membrane protein YebE E3160_16005 ENOG4105X2V dna damage-inducible protein E3160_16010 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR E3160_16015 ENOG4108UHU Aldolase E3160_16020 ENOG4105C01 Dihydroxy-acid dehydratase E3160_16025 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase E3160_16030 ENOG4106KNT transcriptional regulator E3160_16035 ENOG4105CA9 Pyruvate kinase E3160_16040 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase E3160_16045 ENOG4105DR5 peptidase E3160_16050 ENOG4105NXV High-affinity zinc uptake system protein E3160_16060 ENOG4105FAV ABC, transporter E3160_16080 ENOG4107S01 Repressor protein MetJ E3160_16090 ENOG4105CDY transcriptional regulatory protein E3160_16095 ENOG4108TIT dATP pyrophosphohydrolase E3160_16105 ENOG4105D3W isochorismatase E3160_16110 ENOG41081XQ Conserved Protein E3160_16115 ENOG4105WJG Glutathione E3160_16130 ENOG4108J2R molybdopterin oxidoreductase E3160_16135 ENOG4105CUW cytochrome C-TYPE protein E3160_16145 ENOG4106ZCM YecM protein E3160_16160 ENOG4105W13 flagellar protein E3160_16165 ENOG4105D7B Flagellar biosynthesis protein flha E3160_16170 ENOG4105D00 flagellar biosynthetic protein flhB E3160_16180 ENOG4108VYJ response regulator receiver protein E3160_16185 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) E3160_16190 ENOG4105BZU Histidine kinase E3160_16195 ENOG4105C8Q Methyl-accepting chemotaxis E3160_16200 ENOG4105C8Q Methyl-accepting chemotaxis E3160_16205 ENOG4108V3W Chemotaxis protein, CheW E3160_16210 ENOG4105CBS Chea signal transduction histidine kinase E3160_16215 ENOG4105ER2 Ompa motb domain protein E3160_16220 ENOG4107RD7 Flagellar Motor Protein, MotA E3160_16225 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region E3160_16235 ENOG4108VA4 Universal stress protein E3160_16245 ENOG4108K4C ec 3.1.3.12 E3160_16250 ENOG4105CNN ABC, transporter E3160_16255 ENOG4105C2J ABC transporter E3160_16260 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator E3160_16265 ENOG4108UEC Ferritin-like protein E3160_16270 ENOG4105N4N Protein of unknown function (DUF2766) E3160_16280 ENOG4105P23 (LipO)protein E3160_16285 ENOG41090A1 ferritin E3160_16290 ENOG4105VVZ metal-binding protein E3160_16295 ENOG4105E0U tyrosine-specific transport protein E3160_16300 ENOG4106RHG Yeca family E3160_16305 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E3160_16410 ENOG4105ED4 portal protein E3160_16490 ENOG4108X9F tail fiber protein E3160_16490 ENOG4108X9F tail fiber protein E3160_16500 ENOG4105UZW Tail fiber assembly protein E3160_16585 ENOG4105WH1 Two component transcriptional regulator luxr family E3160_16600 ENOG4105XVG cytoplasmic protein E3160_16605 ENOG4105VJY transcriptional regulator E3160_16610 ENOG4105CDA abc transporter atp-binding protein E3160_16615 ENOG4105E5Q amino acid AbC transporter E3160_16625 ENOG4105EAB amino acid AbC transporter E3160_16630 ENOG4108M9K flagella biosynthesis protein FliZ E3160_16635 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3160_16640 ENOG4105I03 Flagellin E3160_16645 ENOG4105DTS flagellar hook-associated E3160_16650 ENOG4105MQ3 flagellar protein FliS E3160_16655 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) E3160_16660 ENOG4105E5K Alpha-amylase E3160_16665 ENOG4108W9D (LipO)protein E3160_16670 ENOG41066VF YeeE YedE family protein E3160_16680 ENOG4108RAV Conserved protein E3160_16685 ENOG4108HF7 Gcn5-related n-acetyltransferase E3160_16700 ENOG4108HF7 Gcn5-related n-acetyltransferase E3160_16715 ENOG4105VQ0 flagellar hook-basal body complex protein fliE E3160_16720 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) E3160_16725 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E3160_16730 ENOG41090PJ Flagellar assembly protein E3160_16735 ENOG4108JIR Flagellum-specific ATP synthase E3160_16740 ENOG4105GSA Flagellar export protein flij E3160_16745 ENOG4105WF4 Flagellar hook-length control protein E3160_16750 ENOG4107ZI8 flagellar basal body-associated protein flil E3160_16755 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E3160_16760 ENOG4105DD5 Flagellar motor switch protein E3160_16765 ENOG4105K0P flagellar biosynthesis protein E3160_16770 ENOG4105CN7 Flagellar biosynthetic protein FliP E3160_16780 ENOG4105D19 Role in flagellar biosynthesis (By similarity) E3160_16785 ENOG4107TKS colanic acid capsular biosynthesis activation protein A E3160_16800 ENOG4105YX3 cellular response to acidity E3160_16810 ENOG4105BZU Histidine kinase E3160_16815 ENOG4105VNZ cytoplasmic protein E3160_16820 ENOG4105CKW Inner membrane protein yedI E3160_16825 ENOG4105FDR Membrane E3160_16830 ENOG41090BB DNA mismatch endonuclease (vsr) E3160_16835 ENOG4105DVF Cytosine-specific methyltransferase E3160_16840 ENOG4105EST Metal Dependent Phosphohydrolase E3160_16855 ENOG4105FCK Membrane E3160_16880 ENOG4107ZY3 Histidine kinase E3160_16885 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E3160_16890 ENOG4105VT2 5-hydroxyisourate hydrolase E3160_16905 ENOG4108MEK Metal-binding protein YodA E3160_16910 ENOG4108VKM cytochrome b561 E3160_16935 ENOG4108X9F tail fiber protein E3160_16950 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3160_17000 ENOG4105IM0 capsid protein E3160_17035 ENOG4106YSC E3160_17075 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_17120 ENOG4105KSK (crossover) junction endodeoxyribonuclease E3160_17125 ENOG4108MXB Protein of unknown function (DUF968) E3160_17215 ENOG4106G8A Qin prophage E3160_17240 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) E3160_17265 ENOG4105CSH Transporter E3160_17270 ENOG4105FYV Amp nucleosidase E3160_17275 ENOG4105CDY transcriptional regulatory protein E3160_17295 ENOG4107R11 Transcriptional regulator E3160_17300 ENOG4106P55 Transcriptional regulator E3160_17310 ENOG4108PXI ErfK YbiS YcfS YnhG E3160_17325 ENOG4108YZT Adenosylcobinamide kinase E3160_17340 ENOG4108YXQ IS66 Orf2 family protein E3160_17345 ENOG4105E5H Transposase E3160_17470 ENOG4108YIV E3160_17495 ENOG4106H6R UPF0380 protein E3160_17500 ENOG4105MFG Antirestriction protein E3160_17505 ENOG4108YGG dna repair protein E3160_17515 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E3160_17550 ENOG4105DR8 Membrane E3160_17560 ENOG4105DZ1 carboxypeptidase E3160_17565 ENOG4105CJB Exodeoxyribonuclease I E3160_17575 ENOG4105CUC YeeE YedE family protein E3160_17580 ENOG4105CUB amino acid E3160_17590 ENOG4105EQ1 Transcriptional regulator E3160_17595 ENOG4107SRH Nad-dependent epimerase dehydratase E3160_17610 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) E3160_17620 ENOG4105ECC imidazole-glycerol-phosphate dehydratase E3160_17625 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) E3160_17655 ENOG4105C6Y Udp-glucose 6-dehydrogenase E3160_17660 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) E3160_17665 ENOG4107WZ3 Transferase E3160_17675 ENOG4107QKV phosphomannomutase E3160_17680 ENOG4105CJT Mannose-1-phosphate guanylyltransferase E3160_17685 ENOG4105FGF GDP-mannose mannosyl hydrolase E3160_17690 ENOG4105C30 Nad-dependent epimerase dehydratase E3160_17695 ENOG4105C0K Gdp-mannose 4,6-dehydratase E3160_17705 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E3160_17725 ENOG4105JEU Glycosyl transferase, family 2 E3160_17730 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E3160_17735 ENOG4105DMT epimerase dehydratase E3160_17740 ENOG4105G1A colanic acid biosynthesis protein E3160_17745 ENOG4107T8Q Glycosyl transferase (Group 1 E3160_17750 ENOG4105C74 pyruvyl transferase E3160_17755 ENOG4105PSV Polysaccharide Biosynthesis Protein E3160_17760 ENOG4105D3Q Sugar transferase E3160_17765 ENOG4107QKV phosphomannomutase E3160_17770 ENOG4105CJT Mannose-1-phosphate guanylyltransferase E3160_17775 ENOG4106CD9 glycosyl transferase group 1 E3160_17780 ENOG4105FGF GDP-mannose mannosyl hydrolase E3160_17785 ENOG4105C30 Nad-dependent epimerase dehydratase E3160_17790 ENOG4105C0K Gdp-mannose 4,6-dehydratase E3160_17795 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF E3160_17800 ENOG4105ECJ Glycosyl Transferase E3160_17805 ENOG4108NYJ Colanic acid E3160_17810 ENOG4107RXY Glycosyl transferase E3160_17815 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB E3160_17820 ENOG41090RK glycosyl transferase E3160_17825 ENOG4105D75 Capsular exopolysaccharide family E3160_17830 ENOG4105KJF protein tyrosine phosphatase E3160_17835 ENOG4105DAY polysaccharide export protein E3160_17840 ENOG4105EE5 Membrane protein terC E3160_17855 ENOG4108GAE asmA family E3160_17865 ENOG4105DBI uridine monophosphokinase E3160_17875 ENOG4105D03 DNA-3-methyladenine glycosylase II E3160_17880 ENOG4105R8A Heat shock protein E3160_17885 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding E3160_17890 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase E3160_17895 ENOG4108M24 von Willebrand factor, type A E3160_17920 ENOG4105BZS acriflavin resistance protein E3160_17935 ENOG4105EB3 Histidine kinase E3160_17940 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3160_17945 ENOG4105KWI UPF0339 protein E3160_17950 ENOG4105CFP Peptidase U32 E3160_17960 ENOG41076Z6 Uncharacterized protein yegR E3160_17975 ENOG4107WTH Galactitol-1-phosphate dehydrogenase E3160_17980 ENOG4105DT3 PTS system, galactitol-specific IIc component E3160_17985 ENOG41090UW PTS System E3160_17990 ENOG41082GB PTS system galactitol-specific transporter subunit IIA E3160_18005 ENOG4105EIE fructose-bisphosphate aldolase E3160_18010 ENOG4105EAA nucleoside E3160_18015 ENOG4108KD5 ADP-ribosylation crystallin J1 E3160_18020 ENOG4108TFM Kinase, PfkB family E3160_18025 ENOG4105FDP GntR family transcriptional regulator E3160_18030 ENOG4108UQ1 hydrolase, family 25 E3160_18035 ENOG4105DWF phosphomethylpyrimidine kinase E3160_18070 ENOG41061MD high-affinity nickel-transporter E3160_18075 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly E3160_18080 ENOG410662B Type-1 fimbrial protein E3160_18085 ENOG4105CW0 outer membrane usher protein E3160_18090 ENOG4108MQF Chaperone E3160_18095 ENOG41063W2 Fimbrial protein E3160_18100 ENOG41067AK Protein of unknown function (DUF2574) E3160_18105 ENOG4105D1F ATP-binding protein E3160_18130 ENOG4108KDT Molybdate metabolism regulator E3160_18135 ENOG4108KDT Molybdate metabolism regulator E3160_18140 ENOG4108KDT Molybdate metabolism regulator E3160_18150 ENOG4105KKX ATPase associated with various cellular activities aaa_5 E3160_18155 ENOG4105RD5 E3160_18160 ENOG4105RD5 E3160_18165 ENOG4105DEG Vwa containing coxe family protein E3160_18170 ENOG410903U zinc ion binding E3160_18175 ENOG4108YCW (LipO)protein E3160_18180 ENOG4108W15 Protein of unknown function (DUF1456) E3160_18185 ENOG4108NEV two component transcriptional regulator, LytTR family E3160_18190 ENOG4108HRK Histidine kinase E3160_18230 ENOG4108X9F tail fiber protein E3160_18250 ENOG4108YXQ IS66 Orf2 family protein E3160_18255 ENOG4105E5H Transposase E3160_18355 ENOG4106YSC E3160_18370 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 E3160_18375 ENOG4105KUS lysozyme E3160_18380 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_18455 ENOG4108MXB Protein of unknown function (DUF968) E3160_18465 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) E3160_18495 ENOG4106050 phage regulatory protein, rha family E3160_18500 ENOG4108S1U E3160_18525 ENOG4105H40 E3160_18530 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) E3160_18535 ENOG4108R7K Metal Dependent Phosphohydrolase E3160_18540 ENOG41077V0 CPS-53 (KpLE1) prophage E3160_18565 ENOG4107R08 Integrase E3160_18570 ENOG4108XDN Transcriptional regulator E3160_18580 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component E3160_18585 ENOG4108IJ8 ABC transporter E3160_18590 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component E3160_18595 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system E3160_18600 ENOG4107QK4 glycoside hydrolase, family 3 domain protein E3160_18605 ENOG4105CXG d-lactate dehydrogenase E3160_18610 ENOG41061WM D-Alanyl-D-Alanine E3160_18615 ENOG41069YE inner membrane protein yohC E3160_18620 ENOG4105KHU inner membrane protein YohD E3160_18625 ENOG4105H9W Short-chain dehydrogenase reductase Sdr E3160_18640 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) E3160_18645 ENOG4105MSY salicylate hydroxylase E3160_18650 ENOG4108RXX maleylacetoacetate isomerase E3160_18680 ENOG41067MG lrgb family E3160_18690 ENOG4107GZ4 SanA protein E3160_18695 ENOG4105Y9N Membrane E3160_18700 ENOG4105BZ8 glutamate synthase E3160_18705 ENOG4107SJI Dehydrogenase E3160_18710 ENOG4108HWV )-transporter E3160_18715 ENOG4105C2J ABC transporter E3160_18720 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator E3160_18725 ENOG41060NJ transcriptional regulator E3160_18730 ENOG4105DHF Membrane E3160_18740 ENOG4105C4W S-formylglutathione hydrolase E3160_18745 ENOG4105D05 Receptor E3160_18755 ENOG4108IQI permease E3160_18760 ENOG4105DUM transcriptional regulator, lysR family E3160_18765 ENOG4105HMI Membrane E3160_18770 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) E3160_18775 ENOG4105DD7 kinase (PfkB family E3160_18780 ENOG4105D9N nucleoside E3160_18790 ENOG4108Y4K DNA-binding transcriptional activator E3160_18795 ENOG4105D9N nucleoside E3160_18800 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) E3160_18805 ENOG4105DD7 kinase (PfkB family E3160_18810 ENOG4105DM4 PTS System E3160_18815 ENOG4105DE4 1-phosphofructokinase E3160_18820 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein E3160_18825 ENOG4105S8Q sugar efflux transporter E3160_18830 ENOG4105KRS Proteinase inhibitor E3160_18840 ENOG4105DEI Mannitol dehydrogenase E3160_18845 ENOG4105CKI cobalamin synthesis protein E3160_18850 ENOG41076MN Phosphoesterase, PA-phosphatase related E3160_18855 ENOG4107TT5 NLP P60 protein E3160_18865 ENOG4105E43 Extracellular solute-binding protein, family 5 E3160_18870 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component E3160_18875 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component E3160_18880 ENOG4108JQ5 ABC transporter E3160_18885 ENOG4105HG6 E3160_18890 ENOG4105C2C drug resistance transporter, Bcr CflA E3160_18895 ENOG4105I08 Pseudouridine synthase E3160_18900 ENOG4105CFI type iii restriction protein res subunit E3160_18920 ENOG4105E68 Sulfatase E3160_18930 ENOG4108MGN ATP-binding component of a transport system E3160_18935 ENOG4105WH1 Two component transcriptional regulator luxr family E3160_18940 ENOG4105KWW Biogenesis protein E3160_18945 ENOG4107QX9 Thiol disulfide interChange protein E3160_18950 ENOG4105DA4 cytochrome c-type biogenesis protein E3160_18960 ENOG4105X3C heme exporter protein E3160_18965 ENOG41060IM Heme exporter protein E3160_18970 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) E3160_18975 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) E3160_18980 ENOG4105CUW cytochrome C-TYPE protein E3160_18985 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) E3160_18990 ENOG4105GXZ Ferredoxin-type protein NapH E3160_18995 ENOG4108BGM Quinol dehydrogenase periplasmic component E3160_19005 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase E3160_19010 ENOG4108ZNS ferredoxin-type protein NapF E3160_19025 ENOG4105IBP Cyclic peptide transporter E3160_19030 ENOG4105CF1 Alkylated DNA repair protein E3160_19035 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E3160_19040 ENOG4105CJ2 (LipO)protein E3160_19045 ENOG4105FCK Membrane E3160_19050 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC E3160_19055 ENOG41068CG regulatoR E3160_19060 ENOG4105BZU Histidine kinase E3160_19065 ENOG4105EDV vault protein E3160_19075 ENOG4107S52 alpha-2-macroglobulin domain protein E3160_19080 ENOG4108QJJ Protein of unknown function (DUF1175) E3160_19085 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) E3160_19090 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3160_19100 ENOG4107GHC outer membrane autotransporter E3160_19105 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3160_19110 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3160_19115 ENOG4105XPH Ferredoxin E3160_19120 ENOG4105FQR PH-inducible protein involved in stress response E3160_19125 ENOG4105CZM Major Facilitator E3160_19130 ENOG4105GZI Transcriptional regulator E3160_19140 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase E3160_19145 ENOG4105CXY transporter E3160_19150 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A E3160_19160 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E3160_19165 ENOG4105DNE Transposase E3160_19170 ENOG4105CNV Aldolase E3160_19175 ENOG4105CSP Major Facilitator Superfamily E3160_19180 ENOG4105CXK mandelate racemase muconate lactonizing E3160_19185 ENOG4107258 Transcriptional regulator E3160_19190 ENOG4108EWA cinA-like protein E3160_19195 ENOG4108UII YfaZ family E3160_19205 ENOG4108WMR Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core (By similarity) E3160_19245 ENOG4106GZG polymyxin resistance protein B E3160_19250 ENOG4105CEY Amp-dependent synthetase and ligase E3160_19260 ENOG4108IPT Naphthoate synthase E3160_19275 ENOG4105E4F Isochorismate synthase E3160_19280 ENOG4105TNS Conserved Protein E3160_19285 ENOG4107YB6 acetyltransferase, (GNAT) family E3160_19295 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is E3160_19305 ENOG4105GDX Domain of unknown function (DUF1877) E3160_19315 ENOG4105C8S subunit m E3160_19320 ENOG4105D65 subunit l E3160_19330 ENOG4107UFS subunit j E3160_19345 ENOG4108IEH NADH dehydrogenase subunit g E3160_19350 ENOG4107QIZ NADH dehydrogenase E3160_19355 ENOG4105GKE subunit e E3160_19375 ENOG4107NQ8 LysR family Transcriptional regulator E3160_19380 ENOG4105CHM Aminotransferase E3160_19390 ENOG4107QWE )-transporter E3160_19395 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 E3160_19400 ENOG4105XWI UPF0304 protein E3160_19410 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E3160_19415 ENOG4105C6K Malic enzyme E3160_19420 ENOG4105CSX c4-dicarboxylate anaerobic carrier E3160_19425 ENOG4105PTV Nudix Hydrolase E3160_19430 ENOG4108RE9 Phosphodiesterase E3160_19450 ENOG4105CYM Glutathione S-transferase E3160_19455 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase E3160_19460 ENOG4105ECP epimerase E3160_19465 ENOG4105DNE Transposase E3160_19470 ENOG4108JEH abc transporter atp-binding protein E3160_19475 ENOG4106YG3 ABC transporter E3160_19480 ENOG4105DSP amino acid AbC transporter E3160_19485 ENOG4105E89 ABC transporter E3160_19490 ENOG4105E89 ABC transporter E3160_19495 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase E3160_19500 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase E3160_19505 ENOG4105E96 Colicin v production protein E3160_19510 ENOG4108S3P Sporulation domain protein E3160_19515 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase E3160_19525 ENOG4105DQR SNARE associated Golgi E3160_19535 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E3160_19545 ENOG4106WZ1 flagella biosynthesis regulator E3160_19550 ENOG4105F9N Major Facilitator Superfamily E3160_19555 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3160_19560 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) E3160_19565 ENOG4105MH2 YfcL protein E3160_19570 ENOG4108BPE -transporting atpase E3160_19575 ENOG4105EJ9 Membrane E3160_19585 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase E3160_19605 ENOG4105US4 fimbrial-like protein yfcP E3160_19610 ENOG4105UGQ Fimbrial E3160_19615 ENOG4105NEV Fimbrial E3160_19620 ENOG4108FZ9 Chaperone E3160_19625 ENOG4106PG1 outer membrane usher protein E3160_19635 ENOG4108BY2 phosphohistidine phosphatase E3160_19650 ENOG4105KZW UPF0381 protein E3160_19655 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation E3160_19670 ENOG410903C (LipO)protein E3160_19675 ENOG4105S64 Formate nitrite transporter E3160_19685 ENOG4105DFP Integrase E3160_19735 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) E3160_19740 ENOG4105D7K pfkb domain protein E3160_19745 ENOG4108HKT sucrose-6-phosphate hydrolase E3160_19750 ENOG4106NDP Transcriptional regulator E3160_19765 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3160_19770 ENOG4105CW7 secretion protein, HlyD family E3160_19775 ENOG4108WQH regulatoR E3160_19780 ENOG4105BZU Histidine kinase E3160_19785 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F E3160_19795 ENOG4108YXQ IS66 Orf2 family protein E3160_19800 ENOG4105E5H Transposase E3160_19805 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F E3160_19810 ENOG4108N2Y auxin Efflux E3160_19815 ENOG4105CFN oxalyl-CoA decarboxylase E3160_19825 ENOG4108V08 YfdX protein E3160_19835 ENOG4105W9M Membrane E3160_19840 ENOG4105D1S lipid A biosynthesis E3160_19850 ENOG4105CHM Aminotransferase E3160_19860 ENOG4105DY9 regulatoR E3160_19865 ENOG4108CIP transcriptional regulator E3160_19870 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E3160_19875 ENOG4105CN9 Peptidase m42 family protein E3160_19880 ENOG4105DC7 peptidase M24 E3160_19885 ENOG410863U PTS System E3160_19890 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) E3160_19900 ENOG4105VCT ion-transport protein YfeO E3160_19905 ENOG4109076 Conserved Protein E3160_19915 ENOG4105D9N nucleoside E3160_19920 ENOG4108KMM Diguanylate cyclase E3160_19935 ENOG4105HZG regulatoR E3160_19940 ENOG4105GXM Putative transcription regulator (DUF1323) E3160_19945 ENOG4105D7V transposase E3160_19985 ENOG4108M0I Transcriptional regulator E3160_19990 ENOG4105DHU Bile acid E3160_19995 ENOG4105VRT cytoplasmic protein E3160_20015 ENOG4105C6T cysteine synthase E3160_20025 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E3160_20030 ENOG4105C5Y PTS System E3160_20045 ENOG4105C6T cysteine synthase E3160_20050 ENOG4108IJ6 ABC transporter E3160_20055 ENOG4105ECW sulfate abc transporter E3160_20060 ENOG4108I5D sulfate abc transporter E3160_20065 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein E3160_20070 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr E3160_20085 ENOG4105C5Y PTS System E3160_20090 ENOG4107QK9 Beta-lactamase E3160_20095 ENOG4105EZR dyp-type peroxidase family protein E3160_20100 ENOG4105E7K (LipO)protein E3160_20105 ENOG4105QZU Inner membrane protein YfeZ E3160_20115 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase E3160_20125 ENOG4108K3Z AraC family transcriptional regulator E3160_20130 ENOG4108X49 Ethanolamine utilization protein EutK E3160_20135 ENOG4106D67 ethanolamine utilization protein E3160_20145 ENOG4105CPD ethanolamine ammonia-lyase E3160_20150 ENOG4105DFP Integrase E3160_20220 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase E3160_20225 ENOG4105ENY Ethanolamine utilization protein eutH E3160_20230 ENOG4105C0A alcohol dehydrogenase E3160_20235 ENOG4107RWI ethanolamine utilization protein eutJ E3160_20240 ENOG4108EKI Dehydrogenase E3160_20245 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml E3160_20250 ENOG4105KNY Microcompartments protein E3160_20255 ENOG4107WUY phosphate acetyltransferase E3160_20260 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase E3160_20270 ENOG4106S4J ethanolamine utilization protein EutP E3160_20275 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place E3160_20280 ENOG4105C6K Malic enzyme E3160_20285 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E3160_20290 ENOG4105CV1 Transketolase (EC 2.2.1.1) E3160_20295 ENOG4108PVD exported protein E3160_20305 ENOG4105BZ8 glutamate synthase E3160_20310 ENOG4105BZU Histidine kinase E3160_20315 ENOG4105BZS acriflavin resistance protein E3160_20330 ENOG4105KUZ arsenate reductase E3160_20345 ENOG4106KED esterase YpfH E3160_20355 ENOG4105CGZ zinc metallopeptidase E3160_20365 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E3160_20375 ENOG4105RH4 Glycine cleavage system transcriptional repressor E3160_20380 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E3160_20385 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) E3160_20390 ENOG4108JPZ Monovalent cation H antiporter subunit D E3160_20395 ENOG4107TDF Formate hydrogenlyase subunit 4 E3160_20400 ENOG4105D65 subunit l E3160_20405 ENOG4107WQX hydrogenase 4 membrane subunit E3160_20410 ENOG4108JPZ Monovalent cation H antiporter subunit D E3160_20415 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E3160_20425 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit E3160_20430 ENOG4105I6X formate hydrogenlyase maturation E3160_20435 ENOG4108JUA Transcriptional regulator E3160_20440 ENOG4105TMB Formate nitrite transporter E3160_20445 ENOG4105C02 permease E3160_20450 ENOG4105ERG peptidase m48, ste24p E3160_20455 ENOG4105K89 arsenate reductase E3160_20460 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) E3160_20465 ENOG4105C2W permease E3160_20480 ENOG4108V3E phosphoribosylglycinamide formyltransferase E3160_20485 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) E3160_20490 ENOG4105C9X ppx gppa phosphatase E3160_20495 ENOG4105BZU Histidine kinase E3160_20500 ENOG41062G3 Protein of unknown function (DUF2633) E3160_20505 ENOG4108ZMA Outer membrane lipoprotein E3160_20510 ENOG41066DY Membrane E3160_20520 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) E3160_20530 ENOG4105VPD cellular component movement E3160_20545 ENOG4105N21 Membrane E3160_20580 ENOG4107KGK dmso reductase anchor subunit E3160_20585 ENOG4105QAX Iron-sulfur E3160_20590 ENOG4107QY8 reductase E3160_20595 ENOG4108JQB penicillin-binding protein 1C E3160_20600 ENOG4105DN3 alpha-2-macroglobulin domain protein E3160_20605 ENOG4105KHC sulfurtransferase E3160_20610 ENOG4105YYA enhanced serine sensitivity protein SseB E3160_20620 ENOG4105WVQ Fe-S assembly protein IscX E3160_20625 ENOG4108ZIT Ferredoxin, 2FE-2S E3160_20645 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins E3160_20665 ENOG4105ECY inositol monophosphatase E3160_20670 ENOG4107XM9 (LipO)protein E3160_20675 ENOG4108MN2 Stationary phase inducible protein CsiE E3160_20680 ENOG4105D8G Major Facilitator superfamily E3160_20685 ENOG4108W5M transcriptional regulator E3160_20690 ENOG4105FUY alpha subunit E3160_20715 ENOG4108SB3 DoxX Family E3160_20720 ENOG4108ZKT aldose 1-epimerase E3160_20725 ENOG4105CPQ Dehydrogenase E3160_20730 ENOG4105CNN ABC, transporter E3160_20735 ENOG4108F37 ATP-binding component of a transport system E3160_20740 ENOG4105FCA ABC transporter periplasmic-binding protein YphF E3160_20745 ENOG4107HQ7 repeat protein E3160_20750 ENOG4108NZE NAGC-like transcriptional regulator E3160_20760 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E3160_20770 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3160_20775 ENOG4108SKK alpha helix protein E3160_20780 ENOG4107WP9 Histidine kinase E3160_20785 ENOG4108ETH Formylglycinamide ribotide synthetase E3160_20790 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) E3160_20795 ENOG4108Z6B deaminase E3160_20800 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB E3160_20805 ENOG4106G6Q Transcriptional regulator E3160_20810 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding E3160_20825 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) E3160_20845 ENOG4105C3F Signal peptidase i E3160_20855 ENOG4105WMJ Positive regulator of sigma E, RseC MucC E3160_20860 ENOG4105VQK sigma E regulatory protein, MucB RseB E3160_20865 ENOG41069PW sigma-e factor negative regulatory protein E3160_20870 ENOG4105EMN RNA polymerase sigma factor E3160_20880 ENOG4108IYU L-aspartate oxidase E3160_20885 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) E3160_20890 ENOG4105C1J atp-dependent rna helicase E3160_20895 ENOG41090KR LysR family transcriptional Regulator E3160_20900 ENOG4108VP3 Lysine exporter protein (LysE YggA) E3160_20915 ENOG4105EIB trna rrna methyltransferase E3160_20920 ENOG4105K63 Thioredoxin E3160_20925 ENOG4106IUH DTW domain containing protein E3160_20930 ENOG4105CD5 CoA-binding domain protein E3160_20935 ENOG4105JIM Phosphatidylserine synthase E3160_20940 ENOG4105T42 (LipO)protein E3160_20945 ENOG4105CSH Transporter E3160_20970 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E3160_20975 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase E3160_20980 ENOG4105C34 Pseudouridine synthase E3160_20985 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane E3160_20990 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA E3160_21000 ENOG4105CQC Prephenate dehydratase E3160_21005 ENOG4105EHE chorismate mutase- prephenate dehydrogenase E3160_21010 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3160_21015 ENOG4105QP9 Protein of unknown function (DUF2799) E3160_21020 ENOG4108WS1 E3160_21025 ENOG4108KHX Diguanylate cyclase E3160_21030 ENOG41090EK ompa motb domain protein E3160_21055 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY E3160_21060 ENOG4106KVJ cytochrome C assembly protein E3160_21065 ENOG4108JU6 CBS domain protein E3160_21085 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) E3160_21090 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E3160_21100 ENOG4108Z1B Cyclase dehydrase E3160_21115 ENOG4106FE3 DNA repair E3160_21125 ENOG4105PI0 Ferredoxin E3160_21280 ENOG4106YSC E3160_21325 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E3160_21350 ENOG4108R1E Serine threonine protein phosphatase 1 E3160_21445 ENOG4105E54 alpha-amylase E3160_21450 ENOG4105E54 alpha-amylase E3160_21460 ENOG4105D5U fad dependent oxidoreductase E3160_21465 ENOG4105C26 Dehydrogenase E3160_21470 ENOG4108JPW Aminotransferase E3160_21475 ENOG4105C85 amino acid E3160_21480 ENOG4108PVQ transcriptional regulator E3160_21485 ENOG4109066 lysm domain bon superfamily protein E3160_21490 ENOG4105VPI YqaE family transport protein E3160_21495 ENOG41080HT Transcriptional regulator, arsr family E3160_21500 ENOG4108V62 Rhodanese domain protein E3160_21505 ENOG4108X73 DNA- binding protein E3160_21510 ENOG4108RNS Exports L-alanine (By similarity) E3160_21515 ENOG4108WMJ Protein of unknown function (DUF2002) E3160_21520 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) E3160_21530 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E3160_21540 ENOG4105WAZ (Glutaredoxin-like protein) NrdH E3160_21550 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3160_21555 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3160_21565 ENOG4108IJ7 Glycine betaine E3160_21570 ENOG4108HQS Glycine betaine E3160_21575 ENOG4105GIJ Glycine betaine E3160_21580 ENOG4105EQ0 Major Facilitator superfamily E3160_21585 ENOG4108UMN azlc family E3160_21590 ENOG4105ZED uncharacterized protein ygaH E3160_21595 ENOG4105NTK Transcriptional repressor Mpra E3160_21600 ENOG4105CW7 secretion protein, HlyD family E3160_21605 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3160_21620 ENOG4105W39 Membrane E3160_21625 ENOG4107VXZ Hydrolase E3160_21655 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) E3160_21660 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) E3160_21675 ENOG4107TH8 cina domain protein E3160_21680 ENOG4105CVE Lytic murein transglycosylase E3160_21685 ENOG410787A Pts system, glucitol sorbitol-specific E3160_21695 ENOG4105VI0 Pts system, glucitol sorbitol-specific E3160_21700 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase E3160_21705 ENOG4105J92 DNA-binding transcriptional activator GutM E3160_21710 ENOG410804X Transcriptional regulator E3160_21715 ENOG4105C2X Arabinose 5-phosphate isomerase E3160_21735 ENOG4105C8H hydrogenase maturation protein Hypf E3160_21740 ENOG4108RC0 Electron transport protein E3160_21745 ENOG4105DDV Transcriptional regulator (LacI family E3160_21750 ENOG4105C5Y PTS System E3160_21755 ENOG4105CS2 ec 3.2.1.21 E3160_21760 ENOG4108MG9 hydrogenase 3 maturation protease E3160_21765 ENOG4105I6X formate hydrogenlyase maturation E3160_21770 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit E3160_21775 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit E3160_21780 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E3160_21785 ENOG4107TDF Formate hydrogenlyase subunit 4 E3160_21790 ENOG4107R30 NADH dehydrogenase E3160_21795 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) E3160_21800 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA E3160_21805 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E3160_21810 ENOG4107RSS Hydrogenase accessory protein HypB E3160_21815 ENOG41083WG hydrogenase assembly chaperone E3160_21820 ENOG4105CQS hydrogenase expression formation protein HypD E3160_21825 ENOG4105C45 hydrogenase expression formation protein (HypE) E3160_21830 ENOG4108JUA Transcriptional regulator E3160_21835 ENOG4105VXR cytoplasmic protein E3160_21845 ENOG4105MEW serine threonine protein phosphatase E3160_21850 ENOG4105KZM cytoplasmic protein E3160_21855 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) E3160_21860 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase E3160_21865 ENOG4105PX9 Transcriptional regulator, MarR family E3160_21870 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3160_21875 ENOG4108K5P (LipO)protein E3160_21910 ENOG4105N0Z inner membrane protein ygbE E3160_21930 ENOG4108MXK alkaline phosphatase isozyme conversion E3160_21935 ENOG4105PWE CRISPR-associated protein cas2 E3160_21940 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) E3160_21950 ENOG4108VWQ crispr-associated protein E3160_21955 ENOG41060M0 Crispr-associated protein, cse4 family E3160_21965 ENOG4105CYR Crispr-associated protein, cse1 family E3160_21970 ENOG4105DTT CRISPR-associated helicase, cas3 E3160_21975 ENOG4107635 Hok Gef family protein E3160_21995 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) E3160_22000 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase E3160_22005 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3160_22010 ENOG4105WQV ferredoxin-like protein E3160_22015 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator E3160_22025 ENOG4106IKH Electron transfer flavoprotein E3160_22040 ENOG4105CHR reductase E3160_22045 ENOG4108ITV Inner membrane protein yqcE E3160_22050 ENOG4108CWB sugar kinase ygcE E3160_22055 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) E3160_22065 ENOG4105HA9 of methanol dehydrogenase type E3160_22075 ENOG4105HA9 of methanol dehydrogenase type E3160_22090 ENOG4105DXN mazG family E3160_22095 ENOG4105MZG transcriptional modulator of maze toxin, mazf E3160_22100 ENOG4106A2Z transcriptional regulator antitoxin, MazE E3160_22105 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E3160_22110 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) E3160_22115 ENOG4105BZU Histidine kinase E3160_22120 ENOG4105EQX glucarate dehydratase E3160_22125 ENOG4105EQX glucarate dehydratase E3160_22130 ENOG4105EQX glucarate dehydratase E3160_22135 ENOG4105DJB Major Facilitator Superfamily E3160_22140 ENOG4105QDK Flavodoxin E3160_22145 ENOG4105DR9 pseudouridine synthase E3160_22150 ENOG4105WP7 tRNA pseudouridine synthase C E3160_22165 ENOG4105EWT decarboxylase family E3160_22170 ENOG4105C44 Serine transporter E3160_22175 ENOG4105EJQ L-serine dehydratase E3160_22185 ENOG4105C0A alcohol dehydrogenase E3160_22190 ENOG4107W7X Aldolase E3160_22195 ENOG4105EDR glucose galactose transporter E3160_22205 ENOG4105CMG Carbohydrate kinase E3160_22215 ENOG4107EDW L-fucose operon activator E3160_22225 ENOG4105M08 Membrane E3160_22230 ENOG4105ETT transcriptional Regulator, LysR family E3160_22235 ENOG4105M5B (LipO)protein E3160_22240 ENOG4105C9B Cysteine desulfurase E3160_22245 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) E3160_22250 ENOG4105CUZ uba thif-type nad fad binding protein E3160_22255 ENOG4105CA3 membrane-bound lytic murein transglycosylase E3160_22275 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E3160_22280 ENOG4108EKC n-acetylglutamate synthase E3160_22285 ENOG4107QYX exodeoxyribonuclease v alpha E3160_22290 ENOG4107QKA exodeoxyribonuclease V beta E3160_22295 ENOG4107QXK peptidase E3160_22300 ENOG4105DSY exodeoxyribonuclease V, gamma E3160_22305 ENOG4105RVB Prepilin peptidase dependent protein c E3160_22310 ENOG4105SEN Protein of unknown function (DUF2509) E3160_22315 ENOG4105JCS prepilin peptidase dependent protein E3160_22320 ENOG4105IPU prepilin peptidase dependent protein A E3160_22335 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase E3160_22355 ENOG4105EE5 Membrane protein terC E3160_22360 ENOG4105SUV lipoprotein YgdR E3160_22365 ENOG4105CPC Aldo Keto reductase E3160_22380 ENOG41060NJ transcriptional regulator E3160_22390 ENOG4105RQF LysR family Transcriptional regulator E3160_22400 ENOG4107QNK )-transporter E3160_22405 ENOG4105CHR reductase E3160_22415 ENOG4105CHU acetyl-coa acetyltransferase E3160_22420 ENOG4108MHD transport protein E3160_22425 ENOG4105ISV protein with bipartite regulator domain E3160_22430 ENOG4108TC1 Transcriptional regulator E3160_22435 ENOG4105FV3 E3160_22465 ENOG4108YAB Invasion protein E3160_22480 ENOG4108YXQ IS66 Orf2 family protein E3160_22485 ENOG4105E5H Transposase E3160_22490 ENOG4105K5T PilT protein E3160_22515 ENOG4108RBT type iii secretion E3160_22520 ENOG4106BTR E3160_22525 ENOG4105Y7Q type iii secretion E3160_22530 ENOG4108RC9 Type III secretion system protein E3160_22550 ENOG4108M6W surface presentation of antigens protein SpaS E3160_22560 ENOG4105U07 type iii secretion E3160_22565 ENOG41075IY surface presentation of antigens protein SpaP E3160_22570 ENOG4105T85 surface presentation of antigens protein E3160_22590 ENOG4108JIR Flagellum-specific ATP synthase E3160_22595 ENOG4108HR8 type iii secretion E3160_22600 ENOG4108N8R Invasion protein E3160_22610 ENOG41090HZ type iii secretion E3160_22620 ENOG4108T88 E3160_22630 ENOG4108K5P (LipO)protein E3160_22635 ENOG4105C7W Xanthine dehydrogenase E3160_22640 ENOG4108HR6 Dehydrogenase E3160_22645 ENOG4108UTP (2Fe-2S)-binding domain protein E3160_22650 ENOG4108JUB Transcriptional regulator E3160_22655 ENOG4105IW6 Carbamoyltransferase E3160_22660 ENOG4107RCH Diaminopropionate ammonia-lyase E3160_22665 ENOG4107S4Y M20 DapE family protein YgeY E3160_22675 ENOG4105C5B carbamate kinase E3160_22680 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family E3160_22685 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC E3160_22690 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase E3160_22695 ENOG4105BZ8 glutamate synthase E3160_22700 ENOG4107UUR Chlorohydrolase aminohydrolase E3160_22705 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase E3160_22710 ENOG4105C7W Xanthine dehydrogenase E3160_22715 ENOG4105C2W permease E3160_22720 ENOG4107QUY Guanine deaminase E3160_22725 ENOG4105C7N Xanthine uracil vitamin C permease E3160_22735 ENOG4105BZ8 glutamate synthase E3160_22740 ENOG4105C2W permease E3160_22760 ENOG4105CRK lysyL-tRNA synthetase E3160_22770 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) E3160_22775 ENOG4105T95 Thiol disulfide interChange protein E3160_22780 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E3160_22785 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) E3160_22790 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB E3160_22795 ENOG4105Y75 tpr repeat protein E3160_22805 ENOG4108UT2 hemolysin iii E3160_22810 ENOG4105N5Z UPF0267 protein E3160_22815 ENOG4105CS2 ec 3.2.1.21 E3160_22840 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E3160_22845 ENOG4105D0A hydroxylase E3160_22850 ENOG4107RAQ aminopeptidase E3160_22870 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase E3160_22885 ENOG4108JQ1 Dehydrogenase E3160_22900 ENOG4105D5P Methylmalonyl-coA mutase E3160_22905 ENOG4105DJT lAO AO transport system ATPase E3160_22910 ENOG4108M7F enoyl-CoA hydratase isomerase E3160_22915 ENOG4105CYC Transferase E3160_22920 ENOG4105DEQ transcriptional regulator E3160_22925 ENOG4105DEQ transcriptional regulator E3160_22930 ENOG4105MPN Membrane E3160_22935 ENOG4108ZUB Lysine exporter protein (Lyse ygga) E3160_22940 ENOG4105D64 Mechanosensitive ion channel E3160_22945 ENOG4105D2N Aldolase E3160_22950 ENOG4105BZA Phosphoglycerate kinase E3160_22975 ENOG4108JJB ABC transporter E3160_22980 ENOG4108JJB ABC transporter E3160_22985 ENOG4107Z1W Fructose transport system kinase E3160_22990 ENOG4108R4K DNA-binding, transcriptional regulator E3160_22995 ENOG4108Q8A Fructose-1,6-bisphosphatase E3160_23000 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein E3160_23005 ENOG4105CTS PTS system mannitol-specific E3160_23010 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia E3160_23015 ENOG4105CV1 Transketolase (EC 2.2.1.1) E3160_23020 ENOG4108K0D peptidase, M48 E3160_23035 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) E3160_23060 ENOG4107QNK )-transporter E3160_23070 ENOG4105RWS endonuclease I E3160_23075 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) E3160_23080 ENOG4105D7Z glutathione synthase E3160_23095 ENOG4105CZX twitching motility protein E3160_23100 ENOG4105DFA alanine racemase domain protein E3160_23105 ENOG4108VIA integral membrane protein E3160_23115 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) E3160_23120 ENOG4105CSA Coproporphyrinogen iii oxidase E3160_23125 ENOG4106MH3 alpha helix chain E3160_23130 ENOG4105HDK L-asparaginase E3160_23135 ENOG4105K33 Periplasmic Protein E3160_23140 ENOG41090ED Protein with unknown function (DUF469) E3160_23150 ENOG4105CEN a g-specific adenine glycosylase E3160_23165 ENOG4105EAA nucleoside E3160_23170 ENOG4105CXN decarboxylase E3160_23175 ENOG4108UQV Membrane E3160_23205 ENOG4108YXQ IS66 Orf2 family protein E3160_23220 ENOG4105H38 Membrane E3160_23280 ENOG4108YXQ IS66 Orf2 family protein E3160_23285 ENOG4105E5H Transposase E3160_23295 ENOG4108YXQ IS66 Orf2 family protein E3160_23320 ENOG4106032 Glutathionylspermidine synthase E3160_23325 ENOG4105CYM Glutathione S-transferase E3160_23330 ENOG41082MF Hydrogenase assembly chaperone hypC hupF E3160_23335 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E3160_23340 ENOG4108WGS hydrogenase 2-specific chaperone E3160_23345 ENOG4108USZ hydrogenase E3160_23350 ENOG4105DPX Hydrogenase, large subunit E3160_23355 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit E3160_23360 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3160_23365 ENOG4105E3S small subunit E3160_23370 ENOG410900S Protein of unknown function (DUF2623) E3160_23380 ENOG4105CPC Aldo Keto reductase E3160_23390 ENOG4105CYX Short-chain dehydrogenase reductase Sdr E3160_23395 ENOG4108ZZF transport protein (ExbD) E3160_23400 ENOG4105CWK Biopolymer transport protein, ExbB E3160_23405 ENOG4105C28 cystathionine E3160_23410 ENOG4108K81 inner membrane protein YghB E3160_23415 ENOG4105CF7 AraC family transcriptional regulator E3160_23420 ENOG4108I6A alcohol dehydrogenase E3160_23425 ENOG4105CV8 reductase E3160_23440 ENOG4105CCT upf0313 protein E3160_23445 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) E3160_23450 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase E3160_23455 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3160_23460 ENOG4108J59 Extracellular solute-binding protein, family 5 E3160_23465 ENOG4105F4I Transcriptional regulator E3160_23470 ENOG4105H4F exported protein E3160_23475 ENOG4105XJC Two component transcriptional regulator (Winged helix family E3160_23480 ENOG4105DHQ Histidine kinase E3160_23485 ENOG4105NF4 modulator of drug activity E3160_23490 ENOG4105VRH Antibiotic biosynthesis monooxygenase E3160_23495 ENOG4106KNT transcriptional regulator E3160_23505 ENOG4105EHG Permease protein E3160_23510 ENOG4105DQ5 transport system permease protein E3160_23515 ENOG4105E0A ABC, transporter E3160_23525 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3160_23530 ENOG4105IPS esterase E3160_23535 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) E3160_23540 ENOG4108SX3 cytoplasmic protein E3160_23545 ENOG41087AY ADP-Ribose pyrophosphatase E3160_23550 ENOG4105DFG type I secretion outer membrane protein E3160_23560 ENOG4106032 Glutathionylspermidine synthase E3160_23565 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b E3160_23580 ENOG4105W0Z cytoplasmic protein E3160_23590 ENOG4105PV3 Inner membrane protein yqiJ E3160_23595 ENOG4107S78 Band 7 protein E3160_23620 ENOG4105I7R Adenylate cyclase E3160_23625 ENOG4106MWK domain protein E3160_23640 ENOG4107ZVW dihydroneopterin aldolase E3160_23650 ENOG4105EJC lysr family transcriptional regulator E3160_23655 ENOG4106DSS Tartrate dehydratase subunit alpha E3160_23660 ENOG4107GFK fumarate E3160_23665 ENOG4107QPK )-transporter E3160_23680 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) E3160_23685 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3160_23700 ENOG4105Q26 Siderophore-interacting protein E3160_23705 ENOG4105NTW Transcriptional regulator E3160_23710 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor E3160_23720 ENOG4108Y51 tRNA-binding protein E3160_23725 ENOG4105CQ4 Transcriptional regulator E3160_23730 ENOG4105CNT hydrolase family 2 E3160_23735 ENOG4105FK9 beta-D-galactosidase beta subunit E3160_23740 ENOG4105E5D amino acid E3160_23745 ENOG4107W6W Conserved Protein E3160_23750 ENOG4107WCA isomerase E3160_23755 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E3160_23760 ENOG4108Z3N Transcriptional regulator E3160_23765 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase E3160_23775 ENOG4108VKG metal-dependent hydrolase E3160_23780 ENOG4108UB4 uncharacterized protein ygjQ E3160_23785 ENOG4105EE0 oxidoreductase E3160_23790 ENOG4105DU1 integral membrane protein, terc E3160_23795 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) E3160_23800 ENOG4105P66 Membrane E3160_23805 ENOG4105CTX dehydratase E3160_23815 ENOG4105DPW Major facilitator superfamily MFS_1 E3160_23820 ENOG4107YCY Transcriptional regulator E3160_23825 ENOG4106W5V Membrane E3160_23830 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) E3160_23835 ENOG4105WAY exported protein E3160_23840 ENOG4105NE1 Conserved Protein E3160_23845 ENOG41090KG Inner membrane protein YqjE E3160_23850 ENOG4105YJD E3160_23855 ENOG4108VBZ doxx family E3160_23860 ENOG4105CHF Glutathione S-transferase E3160_23865 ENOG4105KAF membrAne E3160_23870 ENOG4105KAF membrAne E3160_23875 ENOG4105CWB LysR family transcriptional Regulator E3160_23880 ENOG4108CNN domain protein E3160_23885 ENOG4106D80 Uncharacterized protein YhaL E3160_23895 ENOG4105C44 Serine transporter E3160_23900 ENOG4105EJQ L-serine dehydratase E3160_23905 ENOG4105KME endoribonuclease L-psp E3160_23910 ENOG4105C6N Formate acetyltransferase E3160_23915 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E3160_23925 ENOG4105C7B Threonine dehydratase E3160_23930 ENOG410811B TRANSCRIPTIONal E3160_23955 ENOG4105BZW Glycerate kinase E3160_23960 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3160_23970 ENOG4105DJB Major Facilitator Superfamily E3160_23975 ENOG4105CTX dehydratase E3160_23980 ENOG4105ZEG Suppressor protein E3160_23985 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression E3160_23990 ENOG4105E98 transcriptional regulator DeoR family E3160_24000 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB E3160_24010 ENOG4105F3R pts system mannose fructose sorbose family iid E3160_24015 ENOG4108YTN IIa component E3160_24025 ENOG4105E70 isomerase E3160_24035 ENOG4108UZY PTS System E3160_24045 ENOG4105F3R pts system mannose fructose sorbose family iid E3160_24055 ENOG4105Q10 Fimbrial-like protein E3160_24060 ENOG4108VCD Chaperone E3160_24070 ENOG4105CW0 outer membrane usher protein E3160_24085 ENOG4105I74 Fimbrial protein E3160_24090 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) E3160_24110 ENOG4105W4M Transport-associated protein E3160_24115 ENOG4107S21 permease E3160_24120 ENOG4105K4T epimerase E3160_24125 ENOG4107R7Y intracellular protease Pfpi family E3160_24130 ENOG4108ZPB UPF0306 protein E3160_24140 ENOG4108YYD acetyltransferase E3160_24160 ENOG4105DEN Luciferase family E3160_24165 ENOG4105CIC tryptophan-specific transport protein E3160_24170 ENOG4105C1J atp-dependent rna helicase E3160_24210 ENOG4105CHV Transcription elongation factor NusA E3160_24230 ENOG4105DIJ Phosphoethanolamine transferase E3160_24240 ENOG4105NTZ Preprotein translocase subunit SecG E3160_24250 ENOG4105EEI dihydropteroate synthase E3160_24255 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) E3160_24265 ENOG4105HBR Rna-binding protein E3160_24270 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) E3160_24275 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase E3160_24285 ENOG4105QYV Membrane E3160_24300 ENOG4105EAH synthase E3160_24305 ENOG4105HVQ Regulatory factor of maltose metabolism E3160_24315 ENOG4105VFK BolA family E3160_24320 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane E3160_24325 ENOG4105E3I toluene tolerance E3160_24330 ENOG4107PE3 Mammalian cell entry related domain protein E3160_24335 ENOG4105CY3 ABC transporter, permease E3160_24340 ENOG4105DHJ ABC, transporter E3160_24345 ENOG4105FEU K -dependent Na -Ca exchanger E3160_24350 ENOG4105C2X Arabinose 5-phosphate isomerase E3160_24355 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase E3160_24360 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) E3160_24365 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA E3160_24370 ENOG4108IUZ ABC transporter E3160_24375 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3160_24380 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA E3160_24385 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN E3160_24395 ENOG41080Z8 PHOSPHOCARRIER protein E3160_24400 ENOG4108NIH transferase activity, transferring phosphorus-containing groups E3160_24410 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain E3160_24415 ENOG4105BZU Histidine kinase E3160_24420 ENOG4105N5T Radical SAM Protein E3160_24425 ENOG4105CBC glutamate synthase E3160_24430 ENOG4105BZ8 glutamate synthase E3160_24440 ENOG4108R66 Conserved Protein E3160_24475 ENOG4105KB2 stringent starvation protein b E3160_24480 ENOG4107MKT Stringent starvation protein a E3160_24500 ENOG4105D6Z AFG1 family ATPase E3160_24505 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III E3160_24510 ENOG4105C0H protease E3160_24515 ENOG4105C0H protease E3160_24530 ENOG4105RID UPF0379 protein yhcN E3160_24535 ENOG4105UNR (Barnase) inhibitor E3160_24550 ENOG4105ZQC membrane protein AaeX E3160_24555 ENOG4105CR8 Transcriptional regulator E3160_24560 ENOG4105D1U peptidase U62 modulator of DNA gyrase E3160_24565 ENOG4105QD6 exported protein E3160_24570 ENOG4105C03 ribonuclease E3160_24575 ENOG4108Z03 MAF-like protein E3160_24580 ENOG4105VQ7 Rod shape-determining protein MreD E3160_24585 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) E3160_24600 ENOG41062P1 Diguanylate cyclase phosphodiesterase E3160_24605 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family E3160_24610 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein E3160_24615 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase E3160_24620 ENOG4105RG0 Membrane E3160_24625 ENOG4108IA2 Sodium pantothenate symporter E3160_24635 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E3160_24645 ENOG4105BZS acriflavin resistance protein E3160_24650 ENOG4105XCM membrane LIPOPROTEIN E3160_24660 ENOG4105EZ7 amino acid ABC transporter E3160_24665 ENOG4105DRP amino acid AbC transporter E3160_24670 ENOG4105CDA abc transporter atp-binding protein E3160_24715 ENOG4108Z0R Transferase E3160_24720 ENOG4105SG3 Protein of unknown function (DUF1488) E3160_24730 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) E3160_24735 ENOG4108WI1 Dna topoisomerase E3160_24745 ENOG4105C79 DNA protecting protein DprA E3160_24765 ENOG4105C1A potassium transporter peripheral membrane E3160_24775 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system E3160_24780 ENOG4105W1Y Transcriptional regulator E3160_24785 ENOG4105VTS DnaJ-like, subfamily C E3160_24815 ENOG41067V7 50S ribosomal protein L36 E3160_24820 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) E3160_24865 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) E3160_24910 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) E3160_24940 ENOG4108UQY Iron-storage protein E3160_24945 ENOG4105W53 bacterioferritin-associated ferredoxin E3160_24985 ENOG4105WWK YheO domain protein E3160_24990 ENOG4108V1T peptidylprolyl cis-trans isomerase E3160_25000 ENOG4108YZY peptidylprolyl cis-trans isomerase E3160_25005 ENOG4105VKU nucleicacid-binding protein E3160_25020 ENOG4105C5H ABC transporter E3160_25025 ENOG4105DNZ Alpha Beta Hydrolase E3160_25035 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) E3160_25040 ENOG4108UKZ OsmC family E3160_25050 ENOG410613R integral membrane protein, YccS YhfK family E3160_25055 ENOG4105C8Y Acetylornithine aminotransferase E3160_25060 ENOG4105DDQ anthranilate synthase E3160_25065 ENOG4105MZU cell filamentation protein E3160_25075 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E3160_25090 ENOG4107QZF nitrite reductase NADPH large subunit E3160_25095 ENOG4105WZK nitrite reductase NADPH small subunit E3160_25100 ENOG4107V9H nitrite transporter E3160_25110 ENOG4105VYH E3160_25115 ENOG4107QHQ amino acid E3160_25120 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine E3160_25125 ENOG4107Y0V Not clear, may be involved in an isomerization step E3160_25130 ENOG4108KPW sugar kinase E3160_25135 ENOG4108KPW sugar kinase E3160_25140 ENOG4105FDP GntR family transcriptional regulator E3160_25145 ENOG4105C31 Tryptophanyl-tRNA synthetase E3160_25150 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E3160_25155 ENOG4105DJV ribulose-phosphate 3-epimerase E3160_25160 ENOG4105DFE Dna adenine methylase E3160_25165 ENOG4105EGB membrane protein DamX E3160_25180 ENOG4105E4G Type IV pilus E3160_25185 ENOG4105ITY Required for the use of extracellular DNA as a nutrient E3160_25190 ENOG4105XPX DNA utilization protein HofO E3160_25195 ENOG41065NF Fimbrial assembly family protein E3160_25200 ENOG4108U1Q Pilus assembly protein E3160_25205 ENOG4108JQC penicillin-binding protein 1A E3160_25210 ENOG4107RK2 ADP-ribose diphosphatase NudE E3160_25215 ENOG4105DQY intracellular growth attenuator E3160_25220 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 E3160_25225 ENOG4105VEJ Heat shock protein E3160_25235 ENOG4108MAJ Membrane E3160_25245 ENOG4105E0F Histidine kinase E3160_25255 ENOG4108RRZ Transcription elongation factor GreB E3160_25260 ENOG4105BZM domain protein E3160_25265 ENOG4105XFK Ferrous iron transport protein A E3160_25270 ENOG4105CE1 Ferrous iron transport protein b E3160_25280 ENOG4105DNE Transposase E3160_25290 ENOG4105MJ2 Competence protein E3160_25300 ENOG4105C6Z Gluconate E3160_25305 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) E3160_25310 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E3160_25335 ENOG4105E0Y RtcB Protein E3160_25345 ENOG4105E98 transcriptional regulator DeoR family E3160_25360 ENOG4105C6V Glycerol-3-phosphate dehydrogenase E3160_25380 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E3160_25400 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) E3160_25405 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E3160_25410 ENOG41076UM multiple antibiotic resistance (MarC)-related protein E3160_25425 ENOG4105C9U ATP-dependent DNA helicase RecQ E3160_25430 ENOG4105C9U ATP-dependent DNA helicase RecQ E3160_25435 ENOG4105C6Z Gluconate E3160_25440 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family E3160_25445 ENOG4105DIQ Transcriptional regulator E3160_25450 ENOG4105C2I pirin domain protein E3160_25455 ENOG4105D9R oxidoreductase E3160_25465 ENOG4105WCN acetyltransferase E3160_25480 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) E3160_25485 ENOG4105WC8 Conserved Protein E3160_25490 ENOG4107T6V glycerophosphoryl diester phosphodiesterase E3160_25495 ENOG4108IJ9 (ABC) transporter E3160_25500 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component E3160_25505 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component E3160_25510 ENOG4105BZ7 extracellular solute-binding protein family 1 E3160_25520 ENOG4108IV0 ABC, transporter E3160_25525 ENOG4105C0Z ABC transporter E3160_25530 ENOG4105CF8 branched-chain amino acid ABC transporter, permease E3160_25535 ENOG4105C32 Amino acid ABC transporter (Permease) E3160_25540 ENOG4105CP9 extracellular ligand-binding receptor E3160_25545 ENOG4105U59 -acetyltransferase E3160_25560 ENOG4105CP9 extracellular ligand-binding receptor E3160_25565 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3160_25570 ENOG4105CRP Part of the ABC transporter FtsEX involved in E3160_25575 ENOG4105CAK Cell division ATP-binding protein ftsE E3160_25580 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) E3160_25585 ENOG4106H78 methyltransferase E3160_25590 ENOG4105MG3 Membrane E3160_25600 ENOG4107FS9 Membrane E3160_25615 ENOG4105EX9 Membrane E3160_25620 ENOG4108W1V Lipoprotein E3160_25630 ENOG4105DSF transport protein E3160_25650 ENOG4105E9Q Acyl-transferase E3160_25680 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) E3160_25705 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3160_25715 ENOG4105C2D reductase E3160_25720 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3160_25725 ENOG4107YAK holo-(acyl carrier protein) synthase 2 E3160_25730 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein E3160_25735 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3160_25740 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3160_25745 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E3160_25750 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E3160_25770 ENOG41090UW PTS System E3160_25775 ENOG4105DT3 PTS system, galactitol-specific IIc component E3160_25790 ENOG4105D2N Aldolase E3160_25805 ENOG4105CMI transporter E3160_25810 ENOG4105CJ1 ABC, transporter E3160_25815 ENOG4105D0S secretion protein (HlyD E3160_25830 ENOG4107UNS conserved inner membrane protein E3160_25835 ENOG4105CBX hi0933 family E3160_25840 ENOG4105CJ3 phosphate transporter E3160_25860 ENOG4105DUX Transporter E3160_25870 ENOG4105DGW oligopeptidase A E3160_25875 ENOG4105D6S protein involved in catabolism of external DNA E3160_25880 ENOG4105DC8 reductase E3160_25890 ENOG4105KBH arsR family transcriptional regulator E3160_25895 ENOG4107R5R arsenical pump membrane protein E3160_25900 ENOG4105K89 arsenate reductase E3160_25910 ENOG4105Y4Z Outer Membrane Lipoprotein E3160_25920 ENOG4106QJH hemin transport protein E3160_25925 ENOG4107ENK receptor E3160_25935 ENOG4107R4I Periplasmic binding protein E3160_25940 ENOG4105D4P Coproporphyrinogen iii oxidase E3160_25945 ENOG41090JE Utilization Protein E3160_25955 ENOG4105EHG Permease protein E3160_25960 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) E3160_25965 ENOG4105KT7 mgtC SapB transporter E3160_25970 ENOG4105XXV Acid-resistance protein E3160_25975 ENOG41060V2 Acid-resistance protein E3160_25980 ENOG4108YK4 Acid-resistance membrane protein E3160_25985 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci E3160_25995 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3160_26000 ENOG4105BZS acriflavin resistance protein E3160_26010 ENOG4108NKV transcriptional regulator E3160_26015 ENOG4105CVK Glutamate decarboxylase E3160_26020 ENOG4105CA0 peroxidase E3160_26030 ENOG4106S2D Transcriptional regulator E3160_26035 ENOG4105CBN LysR family transcriptional regulator E3160_26040 ENOG4107H3J ribonuclease E3160_26045 ENOG4105CSH Transporter E3160_26050 ENOG41066T0 asmA family E3160_26055 ENOG4105CMB EAL domain-containing protein E3160_26065 ENOG4105CS0 peptidase E3160_26075 ENOG4105BZU Histidine kinase E3160_26080 ENOG4105EJG cellulose synthase E3160_26085 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) E3160_26090 ENOG4107EEX Cellulose synthase regulator protein E3160_26105 ENOG410661M cytoplasmic protein E3160_26110 ENOG4105U74 cellulose biosynthesis protein BcsE E3160_26115 ENOG4105WQA Cellulose biosynthesis protein BcsF E3160_26120 ENOG4105D1V cellulose synthase operon protein YhjU E3160_26130 ENOG4105C44 Serine transporter E3160_26135 ENOG4108JQ7 (ABC) transporter E3160_26140 ENOG4105C3U ABC transporter E3160_26145 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3160_26150 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3160_26160 ENOG4105DEF Extracellular solute-binding protein, family 5 E3160_26170 ENOG4105DIJ Phosphoethanolamine transferase E3160_26175 ENOG4106UCC Fimbrial protein E3160_26180 ENOG4105MHR Fimbrial protein E3160_26190 ENOG4108VCD Chaperone E3160_26195 ENOG4106EAR Fimbrial protein E3160_26200 ENOG4105FCD Major Facilitator E3160_26205 ENOG4105EAX Putative lipase E3160_26210 ENOG4108R3E Dna-3-methyladenine glycosylase i E3160_26215 ENOG4105HNP -acetyltransferase E3160_26220 ENOG4107QY8 reductase E3160_26225 ENOG4108ZG0 Ompa motb domain protein E3160_26235 ENOG4106JH6 (LipO)protein E3160_26240 ENOG4105MVF Transcriptional regulator E3160_26250 ENOG41060TC Hok gef cell toxic protein E3160_26270 ENOG4105MEV Acyl-transferase E3160_26275 ENOG4108Z12 YiaAB two helix domain-containing protein E3160_26280 ENOG410688U Inner membrane protein yiaB E3160_26285 ENOG4105CMG Carbohydrate kinase E3160_26295 ENOG4105DFW ABC transporter E3160_26305 ENOG4108HWW ABC transporter E3160_26310 ENOG4105T16 Transcriptional regulator (AraC family) E3160_26315 ENOG4108UR8 BAX protein E3160_26320 ENOG4107T9C Alpha amylase catalytic region E3160_26325 ENOG4105JKW Valine--pyruvate aminotransferase E3160_26330 ENOG4108XIB electron transport protein ysaA E3160_26335 ENOG4105J4Q Transcriptional regulator E3160_26345 ENOG4105CT4 transporter E3160_26355 ENOG4105GNX MltA-interacting MipA family protein E3160_26360 ENOG4108Q2M Transcriptional regulator E3160_26365 ENOG4105EFX secretion protein, HlyD family E3160_26370 ENOG4105KK7 inner membrane protein YiaW E3160_26380 ENOG4105C26 Dehydrogenase E3160_26390 ENOG4105C0A alcohol dehydrogenase E3160_26395 ENOG4105EM7 Selenocysteine-specific translation elongation factor E3160_26405 ENOG4108U78 Glutathione S-transferase E3160_26410 ENOG4105CNA YD repeat protein E3160_26435 ENOG4105EFX secretion protein, HlyD family E3160_26440 ENOG4105FP6 Protein of unknown function (DUF3302) E3160_26445 ENOG4105CTS PTS system mannitol-specific E3160_26455 ENOG4105E61 Mannitol repressor protein E3160_26465 ENOG4108YYI Protein of unknown function (DUF2810) E3160_26475 ENOG4108WY4 inner membrane lipoprotein E3160_26480 ENOG4105EUR Domain-Containing protein E3160_26485 ENOG4105DAA L-lactate E3160_26490 ENOG41073TP transcriptional regulator E3160_26500 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) E3160_26505 ENOG4105D7W serine acetyltransferase E3160_26520 ENOG4105VW4 glutaredoxin 3 E3160_26525 ENOG4107YZP Rhodanese domain protein E3160_26540 ENOG41063SB peptidase E3160_26545 ENOG4105PXI polysaccharide deacetylase E3160_26550 ENOG4105K64 Glycosyl transferase, family 2 E3160_26560 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E3160_26565 ENOG4108SEH involved in lipopolysaccharide biosynthesis E3160_26575 ENOG4105XA0 heptosyltransferase ii E3160_26580 ENOG4105D16 lipopolysaccharide heptosyltransferase i E3160_26585 ENOG4108FRV O-antigen ligase E3160_26590 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase E3160_26595 ENOG4105X1N Glycosyl transferase family 8 E3160_26600 ENOG4108PDR lipopolysaccharide core biosynthesis protein E3160_26605 ENOG4106AH0 Glycosyl Transferase E3160_26610 ENOG4107543 (lipo)polysaccharide E3160_26615 ENOG4107RJ7 Glycosyl transferase (Group 1 E3160_26620 ENOG4105DKP glycosyl transferase, family 9 E3160_26625 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase E3160_26645 ENOG4105KDC 50s ribosomal protein l28 E3160_26655 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase E3160_26680 ENOG4105DSJ YicC domain protein E3160_26685 ENOG4105F5P DNA-damage-inducible protein d E3160_26700 ENOG4108YXQ IS66 Orf2 family protein E3160_26705 ENOG4105E5H Transposase E3160_26710 ENOG4105EN6 Membrane E3160_26720 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) E3160_26730 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E3160_26735 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase E3160_26740 ENOG4105CB5 ATP-dependent DNA helicase recG E3160_26750 ENOG4105D6U Sodium Glutamate Symporter E3160_26755 ENOG4105C2W permease E3160_26760 ENOG4105JV1 AsmA family E3160_26765 ENOG4105CJQ hydrolase, family 31 E3160_26770 ENOG4105CT4 transporter E3160_26780 ENOG4105DFP Integrase E3160_26790 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E3160_26860 ENOG4105UQF type iii secretion E3160_26870 ENOG4105TNG K13735 adhesin invasin E3160_26875 ENOG41090V3 Tir chaperone protein (CesT) family E3160_26915 ENOG4108JIR Flagellum-specific ATP synthase E3160_26975 ENOG4108IUF type iii secretion E3160_26980 ENOG4108TN6 type iii secretion E3160_26985 ENOG41083GP type iii secretion E3160_26990 ENOG4108HHI Type III secretion system protein E3160_27040 ENOG4108UZ3 Transporter E3160_27045 ENOG4105D01 (LipO)protein E3160_27050 ENOG4105T8A Uncharacterized protein YicS E3160_27055 ENOG4107RTG Major Facilitator superfamily E3160_27075 ENOG4108SAJ Protein of unknown function (DUF1198) E3160_27090 ENOG4105CXY transporter E3160_27095 ENOG4105CXY transporter E3160_27100 ENOG4105BZU Histidine kinase E3160_27105 ENOG4108KX4 response regulator E3160_27125 ENOG4105M71 acetolactate synthase 1 regulatory subunit E3160_27130 ENOG4105C7K acetolactate synthase E3160_27145 ENOG4105E5M Multidrug resistance protein D E3160_27150 ENOG4105J13 transcriptional regulator E3160_27155 ENOG4105JP4 Inner membrane protein yidG E3160_27160 ENOG4105VG5 Membrane E3160_27165 ENOG4106DRA Inner membrane protein YidI E3160_27170 ENOG4105CBG Sulfatase E3160_27175 ENOG4107RUZ Sss sodium solute transporter superfamily E3160_27180 ENOG4108AHD Transcriptional regulator E3160_27185 ENOG4105F8D glycoside hydrolase family 4 E3160_27190 ENOG4105CI1 PTS System E3160_27195 ENOG4105FDP GntR family transcriptional regulator E3160_27215 ENOG4105R2A (LipO)protein E3160_27220 ENOG4105D99 atp gtp-binding protein E3160_27225 ENOG4107WAP fad NAD(P)-binding domain E3160_27230 ENOG410657R replicase EC 2.7 E3160_27235 ENOG410667J hydrolase E3160_27240 ENOG4105VP5 Bacterial protein of unknown function (DUF937) E3160_27245 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3160_27255 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) E3160_27270 ENOG4105VG0 50S ribosomal protein l34 E3160_27315 ENOG4108P6C Tryptophan transporter of low affinity E3160_27330 ENOG4105E8Q phosphopantetheinyl transferase E3160_27335 ENOG4108YYH Nadph-dependent fmn reductase E3160_27340 ENOG4105C7N Xanthine uracil vitamin C permease E3160_27345 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 E3160_27395 ENOG4108UTW Plays a role in the regulation of phosphate uptake E3160_27400 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) E3160_27405 ENOG4105E2Z phosphate ABC transporter (Permease E3160_27410 ENOG4105C8U phosphate abc transporter E3160_27415 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) E3160_27420 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) E3160_27435 ENOG4105I74 Fimbrial protein E3160_27450 ENOG4108VCD Chaperone E3160_27455 ENOG4108ZI2 Fimbrial protein E3160_27460 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) E3160_27510 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation E3160_27545 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase E3160_27550 ENOG4105DIJ Phosphoethanolamine transferase E3160_27555 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) E3160_27560 ENOG4107BJW polysaccharide deacetylase E3160_27605 ENOG4105E5H Transposase E3160_27610 ENOG4108YXQ IS66 Orf2 family protein E3160_27630 ENOG4106CQM replication E3160_27645 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) E3160_27665 ENOG4105KK6 nuclease E3160_27675 ENOG4107CBI conjugal transfer fertility inhibition protein E3160_27680 ENOG4107U2T alpha beta E3160_27705 ENOG4108N67 choline binding protein E3160_27750 ENOG4105PBD transposase, IS3 IS911 family protein E3160_27845 ENOG4105FEQ ParB domain protein nuclease E3160_27920 ENOG41073YN Protein of unknown function (DUF1380) E3160_27975 ENOG4106JVB Replication Protein E3160_28010 ENOG4105C42 Type I secretion membrane fusion protein (HlyD E3160_28015 ENOG4108JJA ABC, transporter E3160_28020 ENOG4107V48 Hemolysin-type calcium-binding E3160_28025 ENOG41090Q8 at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP E3160_28080 ENOG4105PBE general secretion pathway protein h E3160_28090 ENOG4105D7Q type ii secretion system E3160_28095 ENOG4107QHF type ii secretion system protein e