locus-tag	class	description
E3160_00005	COG0716	FMN binding
E3160_00010	COG1522	sequence-specific DNA binding
E3160_00030	COG3158	transport of potassium into the cell
E3160_00040	COG1129	ABC transporter
E3160_00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_00050	COG1879	ABC-type sugar transport system periplasmic component
E3160_00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_00060	COG1609	Transcriptional regulator
E3160_00065	COG0477	Major facilitator Superfamily
E3160_00070	COG2186	Transcriptional regulator
E3160_00110	COG3085	chromosome segregation
E3160_00115	COG0606	chelatase, subunit chli
E3160_00135	COG3978	acetolactate synthase activity
E3160_00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3160_00150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3160_00155	COG0583	DNA-binding transcription factor activity
E3160_00165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3160_00170	COG3692	DNA binding
E3160_00175	COG0210	DNA helicase
E3160_00190	COG3118	belongs to the thioredoxin family
E3160_00200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3160_00205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3160_00210	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3160_00215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3160_00220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3160_00225	COG1088	dTDP-glucose 4,6-dehydratase activity
E3160_00230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3160_00235	COG0456	acetyltransferase
E3160_00240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3160_00245	COG2244	polysaccharide biosynthetic process
E3160_00265	COG1113	amino acid transport
E3160_00300	COG0641	radical SAM
E3160_00305	COG3119	arylsulfatase activity
E3160_00310	COG3071	HemY protein
E3160_00315	COG2959	enzyme of heme biosynthesis
E3160_00320	COG1587	Uroporphyrinogen-III synthase
E3160_00330	COG3072	Adenylate cyclase
E3160_00345	COG5567	small periplasmic lipoprotein
E3160_00355	COG3159	Protein conserved in bacteria
E3160_00365	COG1011	Hydrolase
E3160_00370	COG0210	DNA helicase
E3160_00375	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
E3160_00380	COG3698	Phosphodiester glycosidase
E3160_00385	COG0598	Magnesium transport protein CorA
E3160_00415	COG2962	Rard protein
E3160_00420	COG2050	protein possibly involved in aromatic compounds catabolism
E3160_00425	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
E3160_00430	COG0514	ATP-dependent DNA helicase (RecQ)
E3160_00435	COG1280	lysine exporter protein (LysE YggA)
E3160_00440	COG1280	lysine exporter protein (LysE YggA)
E3160_00445	COG2267	carboxylic ester hydrolase activity
E3160_00450	COG0561	phosphatase activity
E3160_00455	COG0697	spore germination
E3160_00460	COG0583	DNA-binding transcription factor activity
E3160_00470	COG0412	Dienelactone hydrolase
E3160_00475	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E3160_00480	COG1322	Protein conserved in bacteria
E3160_00490	COG3165	ubiquinone biosynthetic process from chorismate
E3160_00500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3160_00505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3160_00510	COG0805	protein transport
E3160_00515	COG0084	hydrolase, TatD family'
E3160_00520	COG0250	Participates in transcription elongation, termination and antitermination
E3160_00525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3160_00530	COG0543	2 iron, 2 sulfur cluster binding
E3160_00535	COG0183	Belongs to the thiolase family
E3160_00550	COG1739	Uncharacterized protein family UPF0029
E3160_00555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3160_00560	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
E3160_00590	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3160_00595	COG0746	molybdenum cofactor guanylyltransferase activity
E3160_00600	COG3084	Protein conserved in bacteria
E3160_00605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E3160_00610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3160_00615	COG5339	Protein conserved in bacteria
E3160_00620	COG0204	Acyl-transferase
E3160_00630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3160_00630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3160_00640	COG3078	GTPase activator activity
E3160_00645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3160_00655	COG2204	response regulator
E3160_00660	COG3852	Histidine kinase
E3160_00665	COG0174	glutamine synthetase
E3160_00675	COG2188	Transcriptional regulator
E3160_00680	COG1082	Xylose isomerase domain protein TIM barrel
E3160_00685	COG2271	Major facilitator Superfamily
E3160_00690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3160_00695	COG2211	Major facilitator Superfamily
E3160_00700	COG2211	Major facilitator Superfamily
E3160_00705	COG1501	Belongs to the glycosyl hydrolase 31 family
E3160_00715	COG2017	converts alpha-aldose to the beta-anomer
E3160_00720	COG2942	2-epimerase
E3160_00725	COG3684	Belongs to the aldolase LacD family
E3160_00730	COG2084	Dehydrogenase
E3160_00735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_00740	COG1349	DNA-binding transcription factor activity
E3160_00745	COG1011	Hydrolase
E3160_00760	COG0456	acetyltransferase
E3160_00785	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3160_00790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3160_00800	COG2864	formate dehydrogenase
E3160_00805	COG0437	4 iron, 4 sulfur cluster binding
E3160_00825	COG3711	transcriptional antiterminator
E3160_00825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_00830	COG1363	Peptidase, m42
E3160_00835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_00835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_00840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_00880	COG4977	sequence-specific DNA binding
E3160_00880	COG1917	Cupin 2, conserved barrel domain protein
E3160_00890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3160_00900	COG2258	MOSC domain
E3160_00905	COG2205	protein histidine kinase activity
E3160_00910	COG0745	RESPONSE REGULATOR receiver
E3160_00915	COG3678	ATP-independent chaperone mediated protein folding
E3160_00930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
E3160_00950	COG3152	Membrane
E3160_00955	COG3691	Protein conserved in bacteria
E3160_00960	COG0589	response to stress
E3160_00970	COG1494	fructose-1,6-bisphosphatase
E3160_00980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3160_01005	COG1575	Belongs to the MenA family. Type 1 subfamily
E3160_01020	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3160_01025	COG1609	Transcriptional regulator
E3160_01030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3160_01040	COG3209	COG3209 Rhs family protein
E3160_01055	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
E3160_01065	COG0626	cystathionine gamma-synthase activity
E3160_01070	COG0460	homoserine dehydrogenase
E3160_01070	COG0527	aspartate kinase activity
E3160_01075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3160_01085	COG0697	spore germination
E3160_01090	COG3738	Protein conserved in bacteria
E3160_01095	COG0371	Dehydrogenase
E3160_01100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3160_01105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3160_01105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_01105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_01110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_01115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_01120	COG1882	Formate acetyltransferase
E3160_01125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3160_01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_01135	COG2207	Transcriptional regulator
E3160_01140	COG2194	sulfuric ester hydrolase activity
E3160_01155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E3160_01170	COG0583	DNA-binding transcription factor activity
E3160_01180	COG1473	amidohydrolase
E3160_01185	COG0477	Major facilitator Superfamily
E3160_01190	COG1309	transcriptional regulator
E3160_01200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3160_01205	COG4206	TonB-dependent receptor
E3160_01210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E3160_01235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E3160_01240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E3160_01240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E3160_01275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3160_01280	COG0250	Participates in transcription elongation, termination and antitermination
E3160_01320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E3160_01325	COG2022	thiamine diphosphate biosynthetic process
E3160_01330	COG2104	thiamine diphosphate biosynthetic process
E3160_01335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3160_01370	COG3068	Protein conserved in bacteria
E3160_01385	COG3678	ATP-independent chaperone mediated protein folding
E3160_01390	COG4191	Histidine kinase
E3160_01395	COG2204	response regulator
E3160_01400	COG0151	Belongs to the GarS family
E3160_01430	COG0456	acetyltransferase
E3160_01440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E3160_01445	COG2224	Isocitrate lyase
E3160_01460	COG1414	Transcriptional regulator
E3160_01465	COG1410	methionine synthase
E3160_01465	COG0646	methionine synthase
E3160_01470	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3160_01515	COG1187	pseudouridine synthase activity
E3160_01525	COG0527	aspartate kinase activity
E3160_01555	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3160_01570	COG0477	Major facilitator Superfamily
E3160_01570	COG2814	Major facilitator Superfamily
E3160_01575	COG3833	ABC-type maltose transport systems, permease component
E3160_01580	COG1175	transmembrane transport
E3160_01585	COG2182	Extracellular solute-binding protein
E3160_01590	COG3842	ATPase activity
E3160_01605	COG1357	PFAM Pentapeptide repeats (8 copies)
E3160_01625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3160_01635	COG0534	Mate efflux family protein
E3160_01640	COG3237	CsbD-like
E3160_01645	COG0735	belongs to the Fur family
E3160_01655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3160_01685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E3160_01690	COG4197	protein conserved in bacteria, prophage-related
E3160_01750	COG3772	lysozyme
E3160_01870	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_01915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3160_01925	COG0604	alcohol dehydrogenase
E3160_01930	COG0305	Participates in initiation and elongation during chromosome replication
E3160_01935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3160_01940	COG1448	Aminotransferase
E3160_01950	COG3700	Belongs to the class B bacterial acid phosphatase family
E3160_01955	COG0432	Pfam Uncharacterised protein family UPF0047
E3160_01960	COG2315	Protein conserved in bacteria
E3160_01965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E3160_01970	COG0629	single-stranded DNA binding
E3160_01980	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3160_01985	COG2207	Transcriptional regulator
E3160_01990	COG0789	Transcriptional regulator
E3160_01995	COG2252	PERMEase
E3160_02000	COG0025	NhaP-type Na H and K H
E3160_02005	COG1357	PFAM Pentapeptide repeats (8 copies)
E3160_02015	COG3162	membrane
E3160_02020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3160_02030	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E3160_02035	COG0437	4 iron, 4 sulfur cluster binding
E3160_02040	COG3301	Polysulphide reductase, NrfD
E3160_02045	COG1138	Cytochrome C-type biogenesis protein
E3160_02050	COG3088	subunit of a heme lyase
E3160_02055	COG4235	cytochrome complex assembly
E3160_02060	COG1301	dicarboxylic acid transport
E3160_02065	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3160_02080	COG1538	Outer membrane efflux protein
E3160_02085	COG1289	transmembrane transporter activity
E3160_02090	COG1566	PFAM secretion protein HlyD family protein
E3160_02100	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E3160_02110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_02130	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_02135	COG1129	ABC transporter
E3160_02155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3160_02160	COG0456	acetyltransferase
E3160_02165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
E3160_02170	COG3454	Phosphonate metabolism
E3160_02175	COG4778	phosphonate C-P lyase system protein PhnL
E3160_02180	COG4107	phosphonate C-P lyase system protein PhnK
E3160_02185	COG3627	carbon phosphorus lyase activity
E3160_02190	COG3626	phosphonate metabolism
E3160_02195	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
E3160_02200	COG3624	Phosphonate C-P lyase system protein PhnG
E3160_02205	COG2188	Transcriptional regulator
E3160_02210	COG3639	organic phosphonate transmembrane transporter activity
E3160_02215	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
E3160_02220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E3160_02225	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E3160_02230	COG2824	Alkylphosphonate utilization operon protein PhnA
E3160_02235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3160_02245	COG0477	Major facilitator Superfamily
E3160_02255	COG0642	Histidine kinase
E3160_02260	COG0745	RESPONSE REGULATOR receiver
E3160_02265	COG2194	sulfuric ester hydrolase activity
E3160_02270	COG0531	amino acid
E3160_02275	COG2207	Transcriptional regulator
E3160_02280	COG1982	Orn Lys Arg decarboxylase major
E3160_02285	COG2169	Transcriptional regulator
E3160_02290	COG1486	melibiose metabolic process
E3160_02295	COG2211	Major facilitator Superfamily
E3160_02305	COG3647	Membrane
E3160_02310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_02310	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_02315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3160_02325	COG4565	transcriptional regulatory protein
E3160_02330	COG3290	protein histidine kinase activity
E3160_02335	COG3592	Divergent 4Fe-4S mono-cluster
E3160_02340	COG2388	GCN5-related N-acetyl-transferase
E3160_02355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3160_02360	COG3104	oligopeptide transport
E3160_02365	COG1982	Orn Lys Arg decarboxylase major
E3160_02370	COG0531	amino acid
E3160_02380	COG3710	Transcriptional regulator
E3160_02390	COG1309	transcriptional regulator
E3160_02395	COG4232	protein-disulfide reductase activity
E3160_02405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3160_02410	COG1027	Aspartate ammonia-lyase
E3160_02415	COG3030	protein affecting phage T7 exclusion by the F plasmid
E3160_02420	COG0531	amino acid
E3160_02445	COG1509	lysine 2,3-aminomutase activity
E3160_02455	COG5510	response to toxic substance
E3160_02460	COG5510	response to toxic substance
E3160_02465	COG2076	Multidrug Resistance protein
E3160_02470	COG3040	lipid binding
E3160_02475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3160_02490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3160_02495	COG1053	succinate dehydrogenase
E3160_02505	COG0531	amino acid
E3160_02510	COG1511	domain protein
E3160_02510	COG3264	Mechanosensitive ion channel
E3160_02525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E3160_02555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3160_02555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E3160_02560	COG0802	atpase or kinase
E3160_02565	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3160_02585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3160_02590	COG0330	HflC and HflK could
E3160_02595	COG0330	HflC and HflK could
E3160_02600	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E3160_02615	COG0557	exoribonuclease II activity
E3160_02620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3160_02625	COG3789	protein conserved in bacteria
E3160_02630	COG1842	Phage shock protein A
E3160_02640	COG3766	membrane
E3160_02645	COG5463	Belongs to the UPF0441 family
E3160_02650	COG0754	glutathionylspermidine amidase activity
E3160_02655	COG1960	acyl-CoA dehydrogenase activity
E3160_02665	COG3650	response to hydrogen peroxide
E3160_02670	COG1073	alpha beta
E3160_02685	COG3037	sugar-specific permease SgaT UlaA
E3160_02690	COG3414	Phosphotransferase system galactitol-specific IIB component
E3160_02695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_02730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3160_02755	COG0675	Transposase, IS605 OrfB family
E3160_02765	COG3061	Opacity-associated protein A
E3160_02770	COG0545	Peptidyl-prolyl cis-trans isomerase
E3160_02775	COG1113	amino acid transport
E3160_02785	COG0697	spore germination
E3160_02790	COG0702	epimerase
E3160_02795	COG1733	regulation of RNA biosynthetic process
E3160_02800	COG0737	Belongs to the 5'-nucleotidase family
E3160_02805	COG1218	3'(2'),5'-bisphosphate nucleotidase
E3160_02815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E3160_02825	COG1253	flavin adenine dinucleotide binding
E3160_02835	COG0729	surface antigen
E3160_02840	COG2911	Protein conserved in bacteria
E3160_02845	COG2105	PFAM AIG2 family protein
E3160_02850	COG2336	PFAM SpoVT AbrB
E3160_02855	COG2337	Toxic component of a toxin-antitoxin (TA) module
E3160_02860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E3160_02865	COG1879	ABC-type sugar transport system periplasmic component
E3160_02870	COG1129	ABC transporter
E3160_02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_02880	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_02890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E3160_02900	COG0312	modulator of DNA gyrase
E3160_02905	COG3783	Cytochrome b(562)
E3160_02910	COG0602	queuosine metabolic process
E3160_02915	COG1328	CTP reductase activity
E3160_02920	COG0366	Alpha amylase catalytic
E3160_02925	COG1263	PTS System
E3160_02925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_02930	COG1609	Transcriptional regulator
E3160_02940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E3160_02945	COG0251	oxidation-reduction process
E3160_02965	COG0251	oxidation-reduction process
E3160_02970	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_02975	COG1309	transcriptional regulator
E3160_02980	COG2731	YhcH YjgK YiaL family protein
E3160_02990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E3160_02995	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E3160_03000	COG0456	acetyltransferase
E3160_03005	COG4269	membrane
E3160_03015	COG2927	DNA polymerase III (CHI subunit)
E3160_03025	COG0795	lipopolysaccharide-transporting ATPase activity
E3160_03030	COG0795	lipopolysaccharide-transporting ATPase activity
E3160_03035	COG0433	COG0433 Predicted ATPase
E3160_03040	COG1064	alcohol dehydrogenase
E3160_03090	COG0582	viral genome integration into host DNA
E3160_03135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E3160_03145	COG1111	helicase
E3160_03145	COG1205	dead DEAH box helicase
E3160_03150	COG0210	DNA helicase
E3160_03165	COG3436	PFAM IS66 Orf2 family protein
E3160_03170	COG4372	Transposase
E3160_03185	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
E3160_03190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3160_03195	COG0582	viral genome integration into host DNA
E3160_03200	COG4974	Belongs to the 'phage' integrase family
E3160_03210	COG3539	Fimbrial protein
E3160_03215	COG3121	Chaperone
E3160_03220	COG3188	usher protein
E3160_03225	COG3539	Fimbrial protein
E3160_03230	COG3539	Fimbrial protein
E3160_03235	COG3539	Fimbrial protein
E3160_03240	COG2610	gluconate transmembrane transporter activity
E3160_03250	COG0246	Mannitol dehydrogenase
E3160_03255	COG2186	Transcriptional regulator
E3160_03280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3160_03285	COG0700	Nucleoside recognition
E3160_03290	COG3366	ferrous iron transmembrane transporter activity
E3160_03300	COG0477	Major facilitator Superfamily
E3160_03305	COG3204	pilus organization
E3160_03325	COG1924	4 iron, 4 sulfur cluster binding
E3160_03330	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
E3160_03335	COG2733	membrane
E3160_03340	COG2814	Major facilitator Superfamily
E3160_03355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3160_03360	COG5457	Domain of unknown function (DUF1127)
E3160_03380	COG0732	type I restriction modification DNA specificity domain
E3160_03405	COG0523	cobalamin synthesis protein
E3160_03410	COG2879	small protein
E3160_03415	COG1966	Carbon starvation protein
E3160_03425	COG0840	transmembrane signaling receptor activity
E3160_03430	COG2271	Major facilitator Superfamily
E3160_03435	COG1802	Transcriptional regulator
E3160_03440	COG1063	alcohol dehydrogenase
E3160_03455	COG1484	DNA-dependent DNA replication
E3160_03470	COG2966	Psort location CytoplasmicMembrane, score
E3160_03475	COG2197	response regulator
E3160_03480	COG2197	response regulator
E3160_03485	COG4114	ferric iron reductase
E3160_03505	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E3160_03510	COG0456	acetyltransferase
E3160_03515	COG1011	Hydrolase
E3160_03525	COG2823	Periplasmic or secreted lipoprotein
E3160_03535	COG4667	esterase of the alpha-beta hydrolase superfamily
E3160_03540	COG0084	hydrolase, TatD family'
E3160_03545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3160_03580	COG0095	Lipoate-protein ligase
E3160_03580	COG3726	membrane protein affecting hemolysin expression
E3160_03585	COG3726	membrane protein affecting hemolysin expression
E3160_03590	COG0560	Phosphoserine phosphatase
E3160_03595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3160_03600	COG1056	cytidyltransferase-related domain
E3160_03600	COG3172	ATPase kinase involved in NAD metabolism
E3160_03605	COG0488	(ABC) transporter
E3160_03610	COG0741	lytic transglycosylase activity
E3160_03620	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
E3160_03630	COG3708	Transcriptional regulator
E3160_03630	COG2207	Transcriptional regulator
E3160_03635	COG3045	CreA protein
E3160_03640	COG0745	RESPONSE REGULATOR receiver
E3160_03645	COG2205	protein histidine kinase activity
E3160_03650	COG4452	Inner membrane protein CreD
E3160_03655	COG0745	RESPONSE REGULATOR receiver
E3160_03665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E3160_03675	COG0460	homoserine dehydrogenase
E3160_03675	COG0527	aspartate kinase activity
E3160_03685	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3160_03700	COG1115	amino acid carrier protein
E3160_03705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3160_03710	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3160_03715	COG1584	GPR1 FUN34 yaaH family protein
E3160_03720	COG4735	regulation of single-species biofilm formation
E3160_03750	COG0583	DNA-binding transcription factor activity
E3160_03760	COG3188	usher protein
E3160_03765	COG3121	Chaperone
E3160_03790	COG0196	riboflavin kinase activity
E3160_03805	COG1047	Peptidyl-prolyl cis-trans
E3160_03825	COG0505	Belongs to the CarA family
E3160_03830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E3160_03880	COG0644	oxidoreductase
E3160_03885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3160_03890	COG2271	Major facilitator Superfamily
E3160_03905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E3160_03940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3160_03945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3160_03950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E3160_03965	COG0564	pseudouridine synthase activity
E3160_03975	COG0417	DNA replication proofreading
E3160_03980	COG0235	Class ii aldolase
E3160_03995	COG4977	sequence-specific DNA binding
E3160_04000	COG0586	Pfam SNARE associated Golgi protein
E3160_04005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
E3160_04010	COG1178	ABC-type Fe3 transport system permease component
E3160_04015	COG4143	(ABC) transporter
E3160_04035	COG4533	DNA binding
E3160_04055	COG0473	3-isopropylmalate dehydrogenase activity
E3160_04070	COG0583	DNA-binding transcription factor activity
E3160_04075	COG0028	Belongs to the TPP enzyme family
E3160_04080	COG0440	acetolactate synthase activity
E3160_04090	COG1609	Transcriptional regulator
E3160_04105	COG3116	cell division
E3160_04110	COG0768	penicillin binding
E3160_04115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E3160_04120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3160_04130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E3160_04135	COG0772	Belongs to the SEDS family
E3160_04150	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3160_04155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E3160_04160	COG0849	cell division
E3160_04165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3160_04185	COG0494	nUDIX hydrolase
E3160_04200	COG0237	dephospho-CoA kinase activity
E3160_04210	COG1459	type II secretion system
E3160_04215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3160_04220	COG4969	Belongs to the N-Me-Phe pilin family
E3160_04225	COG0157	Belongs to the NadC ModD family
E3160_04230	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3160_04235	COG3725	Membrane protein required for beta-lactamase induction
E3160_04240	COG1113	amino acid transport
E3160_04245	COG2186	Transcriptional regulator
E3160_04250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3160_04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3160_04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3160_04265	COG3064	Membrane
E3160_04270	COG1049	propionate catabolic process, 2-methylcitrate cycle
E3160_04295	COG2132	Multicopper oxidase
E3160_04300	COG4993	Dehydrogenase
E3160_04305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E3160_04310	COG0288	reversible hydration of carbon dioxide
E3160_04315	COG1131	(ABC) transporter
E3160_04320	COG0842	Transport permease protein
E3160_04325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_04330	COG0726	polysaccharide deacetylase
E3160_04340	COG5464	transposase or invertase
E3160_04365	COG3539	Fimbrial protein
E3160_04370	COG3539	Fimbrial protein
E3160_04375	COG3188	usher protein
E3160_04380	COG3121	Chaperone
E3160_04390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3160_04395	COG0617	tRNA 3'-terminal CCA addition
E3160_04400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E3160_04405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3160_04415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E3160_04420	COG1643	Atp-dependent helicase
E3160_04425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3160_04430	COG4774	siderophore transport
E3160_04435	COG1120	ATPase activity
E3160_04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3160_04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_04470	COG2860	membrane
E3160_04475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3160_04490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3160_04495	COG3835	regulator
E3160_04515	COG0024	Methionine aminopeptidase
E3160_04540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E3160_04545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E3160_04550	COG0575	Belongs to the CDS family
E3160_04555	COG0750	zinc metalloprotease
E3160_04565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E3160_04570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E3160_04595	COG0587	DNA-directed DNA polymerase activity
E3160_04610	COG0346	lactoylglutathione lyase activity
E3160_04615	COG0037	tRNA processing
E3160_04620	COG4568	rho-dependent transcription termination
E3160_04630	COG4681	YaeQ
E3160_04635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3160_04640	COG3015	lipoprotein NlpE involved in copper resistance
E3160_04645	COG0791	NLP P60 protein
E3160_04655	COG1720	tRNA m6t6A37 methyltransferase activity
E3160_04665	COG1464	Belongs to the NlpA lipoprotein family
E3160_04670	COG2011	ABC-type metal ion transport system permease component
E3160_04675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E3160_04680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3160_04715	COG0656	L-ascorbic acid biosynthetic process
E3160_04720	COG0583	DNA-binding transcription factor activity
E3160_04730	COG2226	methyltransferase
E3160_04735	COG1388	LysM domain
E3160_04735	COG0741	lytic transglycosylase activity
E3160_04745	COG2226	methyltransferase
E3160_04755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_04875	COG3501	Rhs element vgr protein
E3160_04880	COG3209	COG3209 Rhs family protein
E3160_04890	COG3209	COG3209 Rhs family protein
E3160_04905	COG5433	transposase activity
E3160_04910	COG3209	COG3209 Rhs family protein
E3160_04925	COG5433	transposase activity
E3160_04930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3160_04940	COG1960	acyl-CoA dehydrogenase activity
E3160_04950	COG0121	glutamine amidotransferase
E3160_04955	COG3034	peptidoglycan biosynthetic process
E3160_04960	COG3041	Addiction module toxin RelE StbE family
E3160_04965	COG3077	Addiction module antitoxin, RelB DinJ family
E3160_04970	COG0791	NLP P60 protein
E3160_04990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3160_04995	COG2161	toxin-antitoxin pair type II binding
E3160_05005	COG0454	-acetyltransferase
E3160_05010	COG1690	Belongs to the RtcB family
E3160_05015	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3160_05020	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3160_05040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3160_05070	COG0582	viral genome integration into host DNA
E3160_05140	COG0583	DNA-binding transcription factor activity
E3160_05145	COG4221	oxidoreductase activity
E3160_05160	COG0583	DNA-binding transcription factor activity
E3160_05175	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E3160_05180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3160_05190	COG2080	2 iron, 2 sulfur cluster binding
E3160_05195	COG3477	response to acidic pH
E3160_05200	COG0727	PFAM Uncharacterised protein family (UPF0153)
E3160_05205	COG3121	Chaperone
E3160_05215	COG3188	usher protein
E3160_05260	COG1902	pentaerythritol trinitrate reductase activity
E3160_05265	COG1073	alpha beta
E3160_05270	COG0583	DNA-binding transcription factor activity
E3160_05275	COG4372	Transposase
E3160_05280	COG3436	PFAM IS66 Orf2 family protein
E3160_05310	COG2207	Transcriptional regulator
E3160_05310	COG3708	Transcriptional regulator
E3160_05315	COG0656	L-ascorbic acid biosynthetic process
E3160_05320	COG3059	membrane
E3160_05330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3160_05335	COG2207	Transcriptional regulator
E3160_05340	COG0247	lactate metabolic process
E3160_05345	COG1139	Iron-sulfur cluster binding protein
E3160_05350	COG1556	Lactate utilization protein
E3160_05365	COG3468	outer membrane autotransporter barrel domain protein
E3160_05405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3160_05415	COG2200	EAL domain
E3160_05415	COG2771	luxR family
E3160_05430	COG0666	response to abiotic stimulus
E3160_05440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3160_05445	COG1304	FMN binding
E3160_05455	COG0549	Belongs to the carbamate kinase family
E3160_05460	COG0402	S-adenosylhomocysteine deaminase activity
E3160_05470	COG1879	ABC-type sugar transport system periplasmic component
E3160_05475	COG1129	ABC transporter
E3160_05480	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_05490	COG1064	alcohol dehydrogenase
E3160_05505	COG1280	lysine exporter protein (LysE YggA)
E3160_05515	COG3829	transcription factor binding
E3160_05520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E3160_05525	COG0372	Belongs to the citrate synthase family
E3160_05530	COG2079	MmgE PrpD family protein
E3160_05535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3160_05540	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E3160_05545	COG0402	S-adenosylhomocysteine deaminase activity
E3160_05550	COG0583	DNA-binding transcription factor activity
E3160_05555	COG0288	reversible hydration of carbon dioxide
E3160_05565	COG2807	transmembrane transport
E3160_05570	COG0110	maltose O-acetyltransferase activity
E3160_05575	COG2223	nitrite transmembrane transporter activity
E3160_05580	COG3250	beta-galactosidase activity
E3160_05585	COG1609	Transcriptional regulator
E3160_05595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3160_05600	COG1414	Transcriptional regulator
E3160_05615	COG0596	Alpha beta hydrolase
E3160_05630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E3160_05635	COG2814	Major facilitator Superfamily
E3160_05640	COG3122	Protein conserved in bacteria
E3160_05645	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3160_05660	COG3842	ATPase activity
E3160_05670	COG1840	ABC-type Fe3 transport system, periplasmic component
E3160_05675	COG2271	Major facilitator Superfamily
E3160_05690	COG4521	taurine ABC transporter
E3160_05695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E3160_05700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3160_05705	COG2175	clavaminate synthase activity
E3160_05710	COG0113	porphobilinogen synthase activity
E3160_05715	COG3468	outer membrane autotransporter barrel domain protein
E3160_05720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3160_05725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3160_05730	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E3160_05750	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3160_05760	COG1785	Belongs to the alkaline phosphatase family
E3160_05770	COG3706	GGDEF domain
E3160_05775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3160_05795	COG4126	flavin adenine dinucleotide binding
E3160_05820	COG1940	carbohydrate kinase activity
E3160_05825	COG2814	Major facilitator Superfamily
E3160_05830	COG0419	ATPase involved in DNA repair
E3160_05835	COG0420	3'-5' exonuclease activity
E3160_05840	COG0745	RESPONSE REGULATOR receiver
E3160_05845	COG5002	protein histidine kinase activity
E3160_05850	COG1114	Component of the transport system for branched-chain amino acids
E3160_05855	COG1113	amino acid transport
E3160_05860	COG0366	Alpha amylase catalytic
E3160_05885	COG1862	Preprotein translocase
E3160_05890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3160_05895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3160_05900	COG3609	addiction module antidote protein, CC2985 family
E3160_05910	COG1403	HNH endonuclease
E3160_05915	COG3248	Nucleoside-binding outer membrane protein
E3160_05920	COG4238	major outer membrane lipoprotein
E3160_05930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3160_05930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3160_05945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E3160_05950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E3160_05960	COG0667	Aldo Keto reductase
E3160_05970	COG0142	geranyltranstransferase activity
E3160_05985	COG0693	protein deglycase activity
E3160_05990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3160_06000	COG2814	Major facilitator Superfamily
E3160_06010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E3160_06015	COG1845	cytochrome c oxidase, subunit III
E3160_06020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E3160_06025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E3160_06030	COG2223	nitrite transmembrane transporter activity
E3160_06035	COG3056	Lipoprotein
E3160_06040	COG0271	Belongs to the BolA IbaG family
E3160_06060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3160_06065	COG0776	regulation of translation
E3160_06070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3160_06075	COG1555	photosystem II stabilization
E3160_06080	COG0824	Thioesterase
E3160_06090	COG4533	DNA binding
E3160_06100	COG1522	sequence-specific DNA binding
E3160_06105	COG1132	(ABC) transporter
E3160_06110	COG1132	(ABC) transporter
E3160_06115	COG0347	Belongs to the P(II) protein family
E3160_06120	COG0004	ammonium transporteR
E3160_06125	COG1946	Acyl-CoA thioesterase
E3160_06130	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E3160_06135	COG3695	enzyme binding
E3160_06145	COG5507	3-demethylubiquinone-9 3-methyltransferase
E3160_06150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3160_06160	COG0110	maltose O-acetyltransferase activity
E3160_06175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_06180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_06185	COG1309	transcriptional regulator
E3160_06190	COG1196	nuclear chromosome segregation
E3160_06190	COG3264	Mechanosensitive ion channel
E3160_06200	COG3923	Primosomal replication protein n
E3160_06205	COG2832	Protein of unknown function (DUF454)
E3160_06215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3160_06250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_06255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3160_06255	COG4651	solute:proton antiporter activity
E3160_06260	COG2223	nitrite transmembrane transporter activity
E3160_06265	COG0737	Belongs to the 5'-nucleotidase family
E3160_06270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3160_06275	COG3735	TraB family
E3160_06285	COG3093	addiction module antidote protein HigA
E3160_06290	COG2217	Heavy metal translocating P-type atpase
E3160_06295	COG2066	Belongs to the glutaminase family
E3160_06300	COG0531	amino acid
E3160_06330	COG0789	Transcriptional regulator
E3160_06355	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3160_06360	COG0330	HflC and HflK could
E3160_06365	COG4619	ABC transporter
E3160_06370	COG0390	transport system, permease component
E3160_06375	COG3118	belongs to the thioredoxin family
E3160_06380	COG0300	oxidoreductase activity
E3160_06385	COG2755	lipolytic protein G-D-S-L family
E3160_06390	COG4181	ATPase activity
E3160_06395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E3160_06400	COG3209	COG3209 Rhs family protein
E3160_06420	COG0583	DNA-binding transcription factor activity
E3160_06430	COG1414	Transcriptional regulator
E3160_06435	COG3960	tartronate-semialdehyde synthase activity
E3160_06440	COG3622	Belongs to the hyi family
E3160_06445	COG2084	Dehydrogenase
E3160_06450	COG1953	Uracil, thiamine, allantoin
E3160_06460	COG2233	PERMEase
E3160_06465	COG1929	Belongs to the glycerate kinase type-1 family
E3160_06470	COG3257	ureidoglycine aminohydrolase activity
E3160_06475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3160_06480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3160_06485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3160_06490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3160_06500	COG0549	Belongs to the carbamate kinase family
E3160_06505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E3160_06510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3160_06520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3160_06530	COG1988	membrane-bound metal-dependent
E3160_06535	COG2501	S4 domain
E3160_06545	COG3539	Fimbrial protein
E3160_06550	COG3121	Chaperone
E3160_06555	COG3188	usher protein
E3160_06560	COG3539	Fimbrial protein
E3160_06565	COG3539	Fimbrial protein
E3160_06570	COG2197	response regulator
E3160_06580	COG2207	Transcriptional regulator
E3160_06590	COG4783	chaperone-mediated protein folding
E3160_06600	COG5433	transposase activity
E3160_06610	COG4104	PAAR repeat-containing protein
E3160_06610	COG3209	COG3209 Rhs family protein
E3160_06625	COG3209	COG3209 Rhs family protein
E3160_06625	COG4104	PAAR repeat-containing protein
E3160_06650	COG3501	Rhs element vgr protein
E3160_06655	COG5002	protein histidine kinase activity
E3160_06660	COG0745	RESPONSE REGULATOR receiver
E3160_06665	COG1538	Outer membrane efflux protein
E3160_06670	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_06680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_06685	COG1113	amino acid transport
E3160_06690	COG0668	transmembrane transport
E3160_06695	COG0778	Nitroreductase
E3160_06700	COG2315	Protein conserved in bacteria
E3160_06735	COG2977	Belongs to the P-Pant transferase superfamily
E3160_06740	COG4771	TonB-dependent receptor
E3160_06745	COG2382	esterase
E3160_06750	COG3251	PFAM MbtH domain protein
E3160_06755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3160_06755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E3160_06760	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3160_06765	COG1120	ATPase activity
E3160_06770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_06775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_06785	COG4592	Periplasmic binding protein
E3160_06790	COG1169	isochorismate synthase
E3160_06795	COG1021	2,3-dihydroxybenzoate-AMP ligase
E3160_06800	COG3433	isochorismatase activity
E3160_06800	COG1535	isochorismatase
E3160_06805	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_06815	COG1966	Carbon starvation protein
E3160_06820	COG2879	small protein
E3160_06825	COG0371	Dehydrogenase
E3160_06830	COG0436	Aminotransferase
E3160_06835	COG1475	DNA binding
E3160_06840	COG3969	phosphoadenosine phosphosulfate
E3160_06845	COG0583	DNA-binding transcription factor activity
E3160_06850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3160_06855	COG0450	alkyl hydroperoxide reductase
E3160_06860	COG3634	alkyl hydroperoxide reductase activity
E3160_06865	COG0589	response to stress
E3160_06870	COG1063	alcohol dehydrogenase
E3160_06875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3160_06880	COG3719	Belongs to the RNase T2 family
E3160_06885	COG0471	metal ion transport
E3160_06890	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E3160_06900	COG3051	citrate lyase alpha subunit
E3160_06905	COG2301	Belongs to the HpcH HpaI aldolase family
E3160_06915	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E3160_06920	COG3290	protein histidine kinase activity
E3160_06925	COG4565	transcriptional regulatory protein
E3160_06930	COG3069	C4-dicarboxylate transmembrane transporter activity
E3160_06950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3160_06955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3160_06965	COG0583	DNA-binding transcription factor activity
E3160_06980	COG1686	Belongs to the peptidase S11 family
E3160_06985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3160_06990	COG0772	Belongs to the SEDS family
E3160_06995	COG0768	penicillin binding
E3160_07005	COG0799	negative regulation of ribosome biogenesis
E3160_07010	COG0406	alpha-ribazole phosphatase activity
E3160_07020	COG1466	dna polymerase III delta subunit
E3160_07035	COG2888	peptidyl-tyrosine sulfation
E3160_07050	COG2214	Heat shock protein DnaJ domain protein
E3160_07055	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3160_07065	COG2214	Heat shock protein DnaJ domain protein
E3160_07070	COG2214	Heat shock protein DnaJ domain protein
E3160_07075	COG0443	Heat shock 70 kDa protein
E3160_07085	COG1126	abc transporter atp-binding protein
E3160_07090	COG0765	amino acid transport
E3160_07095	COG0765	amino acid transport
E3160_07100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_07105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E3160_07110	COG4535	Mg2 and Co2 transporter CorC
E3160_07120	COG1702	phosphate starvation-inducible protein PhoH
E3160_07130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3160_07170	COG0367	asparagine synthase
E3160_07175	COG0647	UMP catabolic process
E3160_07180	COG1846	Transcriptional regulator
E3160_07180	COG1940	carbohydrate kinase activity
E3160_07185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3160_07195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_07195	COG1263	PTS System
E3160_07195	COG2190	(PTS) system
E3160_07220	COG0735	belongs to the Fur family
E3160_07230	COG0716	FMN binding
E3160_07240	COG0596	Alpha beta hydrolase
E3160_07245	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E3160_07250	COG0033	Phosphoglucomutase
E3160_07255	COG0531	amino acid
E3160_07260	COG1982	Orn Lys Arg decarboxylase major
E3160_07275	COG0745	RESPONSE REGULATOR receiver
E3160_07280	COG2205	protein histidine kinase activity
E3160_07310	COG3209	COG3209 Rhs family protein
E3160_07335	COG5433	transposase activity
E3160_07340	COG3272	Protein of unknown function (DUF1722)
E3160_07345	COG0415	Belongs to the DNA photolyase family
E3160_07350	COG3104	oligopeptide transport
E3160_07355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E3160_07360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3160_07365	COG1984	allophanate hydrolase subunit 2
E3160_07375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3160_07380	COG3180	Ammonia monooxygenase
E3160_07385	COG3539	Fimbrial protein
E3160_07390	COG3121	Chaperone
E3160_07410	COG3539	Fimbrial protein
E3160_07415	COG0372	Belongs to the citrate synthase family
E3160_07425	COG2009	succinate dehydrogenase
E3160_07430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E3160_07435	COG1053	succinate dehydrogenase
E3160_07440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3160_07445	COG0567	Dehydrogenase, E1 component
E3160_07450	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3160_07460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3160_07475	COG0583	DNA-binding transcription factor activity
E3160_07480	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
E3160_07485	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_07485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_07490	COG1301	dicarboxylic acid transport
E3160_07505	COG3799	methylaspartate ammonia-lyase activity
E3160_07510	COG4865	methylaspartate mutase activity
E3160_07520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3160_07535	COG1271	oxidase subunit
E3160_07540	COG1294	oxidase, subunit
E3160_07545	COG4890	Cyd operon protein YbgT
E3160_07550	COG3790	cyd operon protein YbgE
E3160_07555	COG0824	Thioesterase
E3160_07560	COG0811	peptide transport
E3160_07565	COG0848	biopolymer transport protein
E3160_07570	COG3064	Membrane
E3160_07580	COG2885	chlorophyll binding
E3160_07585	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E3160_07615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E3160_07620	COG3201	nicotinamide mononucleotide transporter
E3160_07625	COG1230	cation diffusion facilitator family transporter
E3160_07635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3160_07645	COG2017	converts alpha-aldose to the beta-anomer
E3160_07655	COG1085	galactose-1-phosphate uridylyltransferase
E3160_07660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E3160_07665	COG1119	ATPase activity
E3160_07670	COG3585	molybdate ion transport
E3160_07670	COG2005	Transcriptional regulator
E3160_07680	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3160_07685	COG4149	molybdate abc transporter
E3160_07695	COG0561	phosphatase activity
E3160_07705	COG0583	DNA-binding transcription factor activity
E3160_07710	COG2828	Protein conserved in bacteria
E3160_07715	COG0471	metal ion transport
E3160_07720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E3160_07725	COG4677	pectinesterase activity
E3160_07730	COG0582	viral genome integration into host DNA
E3160_07885	COG3772	lysozyme
E3160_07955	COG1881	PFAM PEBP family protein
E3160_07960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3160_07975	COG2226	methyltransferase
E3160_07980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3160_07990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3160_08000	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3160_08010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E3160_08015	COG0314	molybdopterin synthase activity
E3160_08020	COG0670	Belongs to the BI1 family
E3160_08030	COG0670	Belongs to the BI1 family
E3160_08035	COG0392	lysyltransferase activity
E3160_08040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3160_08045	COG3568	Endonuclease Exonuclease Phosphatase
E3160_08055	COG0842	Transport permease protein
E3160_08060	COG0842	Transport permease protein
E3160_08065	COG1131	(ABC) transporter
E3160_08075	COG1309	transcriptional regulator
E3160_08080	COG0513	Belongs to the DEAD box helicase family
E3160_08090	COG1199	ATP-dependent helicase activity
E3160_08095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3160_08100	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3160_08110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3160_08120	COG4774	siderophore transport
E3160_08135	COG0668	transmembrane transport
E3160_08140	COG1126	abc transporter atp-binding protein
E3160_08145	COG0765	amino acid transport
E3160_08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_08160	COG5006	permease, DMT superfamily
E3160_08170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3160_08175	COG2194	sulfuric ester hydrolase activity
E3160_08185	COG1321	iron dependent repressor
E3160_08190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3160_08195	COG1376	ErfK ybiS ycfS ynhG family protein
E3160_08200	COG0488	(ABC) transporter
E3160_08210	COG0561	phosphatase activity
E3160_08215	COG1882	Formate acetyltransferase
E3160_08220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3160_08225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3160_08230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3160_08235	COG0303	'Molybdopterin
E3160_08240	COG1446	asparaginase
E3160_08245	COG1446	asparaginase
E3160_08250	COG4172	Belongs to the ABC transporter superfamily
E3160_08255	COG0747	negative chemotaxis
E3160_08260	COG0601	transmembrane transport
E3160_08270	COG2200	EAL domain
E3160_08275	COG2199	diguanylate cyclase activity
E3160_08300	COG2133	pyrroloquinoline quinone binding
E3160_08305	COG0625	glutathione transferase activity
E3160_08310	COG1686	Belongs to the peptidase S11 family
E3160_08315	COG1349	DNA-binding transcription factor activity
E3160_08320	COG0671	phosphoesterase, PA-phosphatase related
E3160_08325	COG2814	Major facilitator Superfamily
E3160_08335	COG0561	phosphatase activity
E3160_08340	COG0738	Major facilitator superfamily
E3160_08345	COG3226	Transcriptional regulator
E3160_08360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3160_08370	COG0778	Nitroreductase
E3160_08385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3160_08390	COG3842	ATPase activity
E3160_08395	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3160_08400	COG1177	transmembrane transport
E3160_08430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_08435	COG4160	amino acid transport
E3160_08440	COG4215	(ABC) transporter
E3160_08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_08450	COG1126	abc transporter atp-binding protein
E3160_08480	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3160_08485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3160_08490	COG0702	epimerase
E3160_08495	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E3160_08500	COG0028	Belongs to the TPP enzyme family
E3160_08505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3160_08515	COG2431	L-lysine efflux transmembrane transporter activity
E3160_08525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3160_08530	COG3593	DNA synthesis involved in DNA repair
E3160_08535	COG2990	Protein conserved in bacteria
E3160_08540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_08545	COG1136	(ABC) transporter
E3160_08545	COG0577	efflux transmembrane transporter activity
E3160_08550	COG1278	Cold shock
E3160_08560	COG0542	response to heat
E3160_08580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3160_08585	COG4988	ABC transporter
E3160_08590	COG0492	ferredoxin-NADP+ reductase activity
E3160_08595	COG1522	sequence-specific DNA binding
E3160_08610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3160_08620	COG0243	molybdopterin cofactor binding
E3160_08625	COG0437	4 iron, 4 sulfur cluster binding
E3160_08630	COG3302	dmso reductase anchor subunit
E3160_08645	COG0531	amino acid
E3160_08655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3160_08660	COG1882	Formate acetyltransferase
E3160_08665	COG2116	formate transmembrane transporter activity
E3160_08670	COG1944	ATP diphosphatase activity
E3160_08675	COG2323	membrane
E3160_08690	COG0501	Belongs to the peptidase M48B family
E3160_08700	COG0539	negative regulation of cytoplasmic translation
E3160_08710	COG2333	competence protein COMEC
E3160_08710	COG0658	competence protein
E3160_08715	COG1132	(ABC) transporter
E3160_08725	COG3214	Protein conserved in bacteria
E3160_08740	COG3173	Aminoglycoside phosphotransferase
E3160_08745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3160_08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3160_08760	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E3160_08770	COG2989	Protein conserved in bacteria
E3160_08775	COG3108	Peptidase M15
E3160_08780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3160_08785	COG1448	Aminotransferase
E3160_08790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3160_08795	COG0017	Asparaginyl-tRNA synthetase
E3160_08805	COG0308	aminopeptidase N
E3160_08810	COG1116	anion transmembrane transporter activity
E3160_08815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3160_08825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E3160_08830	COG0431	NADPH-dependent FMN reductase
E3160_08835	COG3539	Fimbrial protein
E3160_08840	COG3121	Chaperone
E3160_08850	COG3539	Fimbrial protein
E3160_08855	COG3539	Fimbrial protein
E3160_08860	COG3539	Fimbrial protein
E3160_08880	COG0633	Ferredoxin
E3160_08880	COG3217	Mosc domain protein beta barrel domain protein
E3160_08890	COG0488	(ABC) transporter
E3160_08895	COG2995	paraquat-inducible protein a
E3160_08900	COG3008	intermembrane lipid transfer
E3160_08900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3160_08905	COG3009	Protein conserved in bacteria
E3160_08910	COG3130	regulation of translation
E3160_08920	COG1067	ATP-dependent peptidase activity
E3160_08930	COG2885	chlorophyll binding
E3160_08930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3160_08940	COG3070	regulator of competence-specific genes
E3160_08945	COG1289	transmembrane transporter activity
E3160_08950	COG3304	Inner membrane component domain
E3160_08955	COG0210	DNA helicase
E3160_08970	COG1832	CoA-binding protein
E3160_08985	COG1254	Belongs to the acylphosphatase family
E3160_08990	COG2920	part of a sulfur-relay system
E3160_08995	COG0670	Belongs to the BI1 family
E3160_09015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_09085	COG1484	DNA-dependent DNA replication
E3160_09090	COG1846	Transcriptional regulator
E3160_09125	COG1403	HNH endonuclease
E3160_09130	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_09150	COG2207	Transcriptional regulator
E3160_09195	COG3772	lysozyme
E3160_09290	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_09315	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3160_09320	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3160_09325	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E3160_09330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3160_09335	COG1999	signal sequence binding
E3160_09340	COG1773	rubredoxin
E3160_09345	COG1271	oxidase subunit
E3160_09350	COG1294	oxidase, subunit
E3160_09365	COG0489	protein tyrosine kinase activity
E3160_09365	COG3206	protein involved in exopolysaccharide biosynthesis
E3160_09370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E3160_09375	COG1596	polysaccharide export
E3160_09380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3160_09400	COG1278	Cold shock
E3160_09405	COG1278	Cold shock
E3160_09430	COG0348	domain, Protein
E3160_09435	COG2198	Histidine kinase
E3160_09435	COG2205	protein histidine kinase activity
E3160_09435	COG0784	Response regulator, receiver
E3160_09440	COG1879	ABC-type sugar transport system periplasmic component
E3160_09445	COG0745	RESPONSE REGULATOR receiver
E3160_09450	COG3005	denitrification pathway
E3160_09455	COG0243	molybdopterin cofactor binding
E3160_09495	COG3729	General stress protein
E3160_09500	COG2233	PERMEase
E3160_09540	COG1309	transcriptional regulator
E3160_09545	COG0506	proline dehydrogenase activity
E3160_09545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3160_09545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3160_09555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3160_09570	COG2822	iron ion transport
E3160_09575	COG2837	iron assimilation
E3160_09580	COG1702	phosphate starvation-inducible protein PhoH
E3160_09585	COG3658	cytochrome
E3160_09590	COG1215	transferase activity, transferring glycosyl groups
E3160_09595	COG0726	polysaccharide deacetylase
E3160_09595	COG1649	PFAM Uncharacterised BCR, COG1649
E3160_09600	COG0457	Tetratricopeptide repeat
E3160_09605	COG3706	GGDEF domain
E3160_09610	COG2200	EAL domain
E3160_09620	COG3710	Transcriptional regulator
E3160_09625	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_09630	COG3121	Chaperone
E3160_09650	COG3539	Fimbrial protein
E3160_09660	COG3210	domain, Protein
E3160_09665	COG2831	hemolysin activation secretion protein
E3160_09670	COG0736	holo-[acyl-carrier-protein] synthase activity
E3160_09680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E3160_09690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E3160_09695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3160_09745	COG0582	viral genome integration into host DNA
E3160_09775	COG4983	Phage plasmid primase, P4 family domain protein
E3160_09820	COG3436	PFAM IS66 Orf2 family protein
E3160_09855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3160_09860	COG2194	sulfuric ester hydrolase activity
E3160_09870	COG0829	nickel cation binding
E3160_09915	COG0254	rRNA binding
E3160_09965	COG3436	PFAM IS66 Orf2 family protein
E3160_09970	COG4372	Transposase
E3160_10005	COG1358	cellular component organization or biogenesis
E3160_10055	COG3547	Transposase (IS116 IS110 IS902 family)
E3160_10070	COG4771	TonB-dependent receptor
E3160_10170	COG2831	hemolysin activation secretion protein
E3160_10190	COG3468	outer membrane autotransporter barrel domain protein
E3160_10225	COG2003	Belongs to the UPF0758 family
E3160_10275	COG3381	protein complex oligomerization
E3160_10290	COG4372	Transposase
E3160_10295	COG3436	PFAM IS66 Orf2 family protein
E3160_10320	COG2197	response regulator
E3160_10345	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3160_10350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3160_10365	COG2943	transferase activity, transferring hexosyl groups
E3160_10370	COG5645	(Lipo)protein
E3160_10385	COG1560	Kdo2-lipid A biosynthetic process
E3160_10395	COG2353	YceI-like domain
E3160_10400	COG3038	cytochrome b561
E3160_10435	COG2999	glutathione oxidoreductase activity
E3160_10445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3160_10455	COG0673	inositol 2-dehydrogenase activity
E3160_10460	COG0728	peptidoglycan biosynthetic process
E3160_10465	COG3418	PFAM FlgN family protein
E3160_10470	COG2747	anti-sigma28 factor FlgM
E3160_10475	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
E3160_10480	COG1815	bacterial-type flagellum-dependent cell motility
E3160_10485	COG1558	bacterial-type flagellum-dependent cell motility
E3160_10490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E3160_10495	COG1749	Flagellar hook protein flgE
E3160_10500	COG4787	bacterial-type flagellum-dependent cell motility
E3160_10505	COG4786	Flagellar basal body rod
E3160_10520	COG3951	Flagellar rod assembly protein muramidase FlgJ
E3160_10520	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3160_10525	COG1256	bacterial-type flagellum assembly
E3160_10530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E3160_10535	COG1530	ribonuclease E activity
E3160_10545	COG0564	pseudouridine synthase activity
E3160_10550	COG0424	maF-like protein
E3160_10555	COG1399	metal-binding, possibly nucleic acid-binding protein
E3160_10575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E3160_10580	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_10590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3160_10595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3160_10600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E3160_10610	COG0470	DNA polymerase III
E3160_10615	COG0084	hydrolase, TatD family'
E3160_10620	COG1263	PTS System
E3160_10620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_10625	COG4773	Receptor
E3160_10635	COG0537	adenosine 5'-monophosphoramidase activity
E3160_10640	COG5633	Lipoprotein
E3160_10645	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
E3160_10650	COG0510	thiamine kinase activity
E3160_10665	COG1252	NADH dehydrogenase
E3160_10670	COG3134	Outer membrane lipoprotein
E3160_10675	COG1309	transcriptional regulator
E3160_10685	COG1388	LysM domain
E3160_10685	COG1376	ErfK ybiS ycfS ynhG family protein
E3160_10690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E3160_10700	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3160_10705	COG1136	(ABC) transporter
E3160_10710	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3160_10720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E3160_10725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3160_10730	COG1177	transmembrane transport
E3160_10735	COG0582	viral genome integration into host DNA
E3160_10765	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_10835	COG3842	ATPase activity
E3160_10845	COG2850	peptidyl-arginine hydroxylation
E3160_10945	COG4626	Terminase
E3160_10945	COG1802	Transcriptional regulator
E3160_10960	COG2205	protein histidine kinase activity
E3160_10965	COG0745	RESPONSE REGULATOR receiver
E3160_10970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3160_10980	COG0482	sulfurtransferase activity
E3160_10990	COG1187	pseudouridine synthase activity
E3160_10995	COG0538	isocitrate dehydrogenase activity
E3160_11000	COG0582	viral genome integration into host DNA
E3160_11045	COG5562	phage envelope protein
E3160_11060	COG4220	transposase activity
E3160_11080	COG1030	water channel activity
E3160_11130	COG1196	nuclear chromosome segregation
E3160_11170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3160_11175	COG3546	catalase activity
E3160_11180	COG3685	Protein conserved in bacteria
E3160_11185	COG3685	Protein conserved in bacteria
E3160_11190	COG3729	General stress protein
E3160_11200	COG0500	methyltransferase
E3160_11215	COG3436	PFAM IS66 Orf2 family protein
E3160_11220	COG4372	Transposase
E3160_11240	COG4571	Outer membrane protease
E3160_11250	COG0456	acetyltransferase
E3160_11255	COG0538	isocitrate dehydrogenase activity
E3160_11270	COG5562	phage envelope protein
E3160_11275	COG0789	Transcriptional regulator
E3160_11280	COG2200	EAL domain
E3160_11305	COG2200	EAL domain
E3160_11360	COG2894	cell division
E3160_11385	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3160_11400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E3160_11405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3160_11410	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E3160_11425	COG2719	SpoVR family
E3160_11435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3160_11460	COG1619	proteins homologs of microcin C7 resistance protein MccF
E3160_11470	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
E3160_11485	COG0157	Belongs to the NadC ModD family
E3160_11490	COG0500	methyltransferase
E3160_11495	COG1120	ATPase activity
E3160_11515	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E3160_11525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3160_11525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_11525	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3160_11530	COG1461	Dihydroxyacetone kinase
E3160_11535	COG2376	Dihydroxyacetone kinase
E3160_11540	COG3284	Transcriptional regulator
E3160_11560	COG0012	GTP binding
E3160_11575	COG0659	secondary active sulfate transmembrane transporter activity
E3160_11580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E3160_11610	COG3094	Invasion gene expression up-regulator, SirB
E3160_11615	COG2912	Transglutaminase-like superfamily
E3160_11635	COG0387	Pfam Sodium calcium exchanger
E3160_11640	COG4572	Cation transport regulator
E3160_11645	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
E3160_11650	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3160_11655	COG4932	domain protein
E3160_11660	COG2197	response regulator
E3160_11665	COG3850	Histidine kinase
E3160_11670	COG2223	nitrite transmembrane transporter activity
E3160_11675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3160_11680	COG1140	nitrate reductase beta subunit
E3160_11685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3160_11690	COG2181	nitrate reductase activity
E3160_11720	COG0788	formyltetrahydrofolate deformylase activity
E3160_11730	COG1752	Esterase of the alpha-beta hydrolase superfamily
E3160_11735	COG0745	RESPONSE REGULATOR receiver
E3160_11740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3160_11750	COG1435	thymidine kinase activity
E3160_11755	COG1012	belongs to the aldehyde dehydrogenase family
E3160_11755	COG1454	alcohol dehydrogenase
E3160_11760	COG2095	MarC family integral membrane protein
E3160_11765	COG4166	transmembrane transport
E3160_11770	COG0601	transmembrane transport
E3160_11775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3160_11780	COG0444	Belongs to the ABC transporter superfamily
E3160_11785	COG4608	Belongs to the ABC transporter superfamily
E3160_11805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3160_11810	COG2350	Protein conserved in bacteria
E3160_11815	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E3160_11820	COG1607	acyl-coa hydrolase
E3160_11840	COG3047	cAMP biosynthetic process
E3160_11845	COG3685	Protein conserved in bacteria
E3160_11850	COG3685	Protein conserved in bacteria
E3160_11855	COG3729	General stress protein
E3160_11870	COG0135	phosphoribosylanthranilate isomerase activity
E3160_11870	COG0134	indole-3-glycerol-phosphate synthase activity
E3160_11875	COG0512	Glutamine amidotransferase of anthranilate synthase
E3160_11875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3160_11880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3160_11890	COG0613	PHP domain protein
E3160_11895	COG0009	L-threonylcarbamoyladenylate synthase
E3160_11900	COG4907	membrane protein (DUF2207)
E3160_11905	COG1187	pseudouridine synthase activity
E3160_11910	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
E3160_11915	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_11920	COG0616	signal peptide processing
E3160_11930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3160_11935	COG0583	DNA-binding transcription factor activity
E3160_11955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E3160_11965	COG0671	phosphoesterase, PA-phosphatase related
E3160_11970	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E3160_11975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E3160_11985	COG0023	Translation Initiation Factor
E3160_11995	COG1349	DNA-binding transcription factor activity
E3160_12005	COG5001	Diguanylate cyclase
E3160_12015	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3160_12015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3160_12020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E3160_12030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_12035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_12045	COG2814	Major facilitator Superfamily
E3160_12050	COG4172	Belongs to the ABC transporter superfamily
E3160_12055	COG4172	Belongs to the ABC transporter superfamily
E3160_12060	COG4171	peptide transport system, permease
E3160_12065	COG4168	peptide transport system, permease
E3160_12070	COG4166	transmembrane transport
E3160_12080	COG0531	amino acid
E3160_12090	COG0174	glutamine synthetase
E3160_12095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E3160_12100	COG1917	Cupin 2, conserved barrel domain protein
E3160_12100	COG1396	sequence-specific DNA binding
E3160_12105	COG1012	belongs to the aldehyde dehydrogenase family
E3160_12110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3160_12115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3160_12120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3160_12125	COG1842	Phage shock protein A
E3160_12135	COG1983	PspC domain protein
E3160_12145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3160_12150	COG0366	Alpha amylase catalytic
E3160_12155	COG0366	Alpha amylase catalytic
E3160_12165	COG1175	transmembrane transport
E3160_12170	COG0395	ABC-type sugar transport system, permease component
E3160_12175	COG1063	alcohol dehydrogenase
E3160_12180	COG1082	Xylose isomerase domain protein TIM barrel
E3160_12185	COG0673	inositol 2-dehydrogenase activity
E3160_12190	COG1554	hydrolase, family 65, central catalytic
E3160_12195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3160_12200	COG3842	ATPase activity
E3160_12210	COG1609	Transcriptional regulator
E3160_12215	COG3106	COG3106 Predicted ATPase
E3160_12225	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E3160_12230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E3160_12235	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_12240	COG2866	Carboxypeptidase
E3160_12255	COG0702	epimerase
E3160_12265	COG1073	alpha beta
E3160_12270	COG0583	DNA-binding transcription factor activity
E3160_12275	COG4166	transmembrane transport
E3160_12280	COG0668	transmembrane transport
E3160_12285	COG3182	Iron-regulated membrane protein
E3160_12290	COG0589	response to stress
E3160_12295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3160_12300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3160_12305	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3160_12310	COG1473	amidohydrolase
E3160_12315	COG1473	amidohydrolase
E3160_12320	COG0583	DNA-binding transcription factor activity
E3160_12325	COG2840	Smr protein MutS2
E3160_12330	COG3706	GGDEF domain
E3160_12345	COG0513	Belongs to the DEAD box helicase family
E3160_12355	COG0582	viral genome integration into host DNA
E3160_12375	COG3723	Recombinational DNA repair protein, rece pathway
E3160_12410	COG3646	Phage regulatory protein
E3160_12455	COG1484	DNA-dependent DNA replication
E3160_12460	COG1846	Transcriptional regulator
E3160_12545	COG3772	lysozyme
E3160_12580	COG0582	viral genome integration into host DNA
E3160_12640	COG0740	serine-type endopeptidase activity
E3160_12665	COG0740	serine-type endopeptidase activity
E3160_12740	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_12765	COG0589	response to stress
E3160_12770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3160_12775	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3160_12775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3160_12775	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3160_12775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3160_12780	COG3042	response to heat
E3160_12785	COG3187	Heat shock protein
E3160_12790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3160_12795	COG2911	Protein conserved in bacteria
E3160_12805	COG3784	Protein of unknown function (DUF1318)
E3160_12820	COG0667	Aldo Keto reductase
E3160_12830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E3160_12835	COG4589	Belongs to the CDS family
E3160_12840	COG2267	carboxylic ester hydrolase activity
E3160_12845	COG0671	phosphoesterase, PA-phosphatase related
E3160_12845	COG2453	phosphatase
E3160_12850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E3160_12855	COG1643	Atp-dependent helicase
E3160_12880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3160_12885	COG1012	belongs to the aldehyde dehydrogenase family
E3160_12890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3160_12895	COG3038	cytochrome b561
E3160_12915	COG0840	transmembrane signaling receptor activity
E3160_12920	COG0583	DNA-binding transcription factor activity
E3160_12925	COG5383	Protein conserved in bacteria
E3160_12935	COG2841	Protein conserved in bacteria
E3160_12940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3160_12945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3160_12950	COG1275	C4-dicarboxylate transporter malic acid transport protein
E3160_12955	COG0500	methyltransferase
E3160_12965	COG3135	benzoate transporter
E3160_12970	COG1396	sequence-specific DNA binding
E3160_12975	COG0826	peptidase U32
E3160_12985	COG1724	mRNA binding
E3160_12990	COG1598	PFAM Uncharacterised protein family UPF0150
E3160_12995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3160_13000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3160_13005	COG3842	ATPase activity
E3160_13010	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3160_13015	COG1177	transmembrane transport
E3160_13040	COG3238	Protein conserved in bacteria
E3160_13045	COG1247	-acetyltransferase
E3160_13050	COG2130	NADP-dependent
E3160_13055	COG1802	Transcriptional regulator
E3160_13060	COG4772	TonB-dependent receptor
E3160_13065	COG3391	amine dehydrogenase activity
E3160_13070	COG1113	amino acid transport
E3160_13075	COG0625	glutathione transferase activity
E3160_13085	COG3501	Rhs element vgr protein
E3160_13090	COG3209	COG3209 Rhs family protein
E3160_13120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3160_13125	COG2162	N-hydroxyarylamine O-acetyltransferase activity
E3160_13130	COG0384	phenazine biosynthesis protein PhzF
E3160_13135	COG2181	nitrate reductase activity
E3160_13140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3160_13145	COG1140	nitrate reductase beta subunit
E3160_13150	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3160_13155	COG2223	nitrite transmembrane transporter activity
E3160_13160	COG4886	Leucine-rich repeat (LRR) protein
E3160_13165	COG4886	Leucine-rich repeat (LRR) protein
E3160_13180	COG0697	spore germination
E3160_13185	COG3383	formate dehydrogenase (NAD+) activity
E3160_13185	COG0243	molybdopterin cofactor binding
E3160_13190	COG0243	molybdopterin cofactor binding
E3160_13190	COG3383	formate dehydrogenase (NAD+) activity
E3160_13195	COG0437	4 iron, 4 sulfur cluster binding
E3160_13200	COG2864	formate dehydrogenase
E3160_13205	COG3093	addiction module antidote protein HigA
E3160_13210	COG1064	alcohol dehydrogenase
E3160_13230	COG1764	response to oxidative stress
E3160_13235	COG4608	Belongs to the ABC transporter superfamily
E3160_13240	COG0444	Belongs to the ABC transporter superfamily
E3160_13245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3160_13250	COG0601	transmembrane transport
E3160_13260	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E3160_13265	COG2200	EAL domain
E3160_13265	COG2202	Pas domain
E3160_13265	COG2199	diguanylate cyclase activity
E3160_13270	COG3706	GGDEF domain
E3160_13280	COG0531	amino acid
E3160_13285	COG0076	glutamate decarboxylase activity
E3160_13290	COG0612	Peptidase, M16
E3160_13295	COG4771	TonB-dependent receptor
E3160_13300	COG4178	(ABC) transporter
E3160_13310	COG0641	radical SAM
E3160_13315	COG3119	arylsulfatase activity
E3160_13320	COG2207	Transcriptional regulator
E3160_13330	COG0243	molybdopterin cofactor binding
E3160_13335	COG3539	Fimbrial protein
E3160_13340	COG3539	Fimbrial protein
E3160_13345	COG3539	Fimbrial protein
E3160_13350	COG3188	usher protein
E3160_13360	COG3539	Fimbrial protein
E3160_13375	COG3550	peptidyl-serine autophosphorylation
E3160_13380	COG1396	sequence-specific DNA binding
E3160_13395	COG1070	Carbohydrate kinase
E3160_13405	COG1129	ABC transporter
E3160_13410	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_13415	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_13425	COG1830	Aldolase
E3160_13440	COG3781	membrane
E3160_13450	COG2199	diguanylate cyclase activity
E3160_13460	COG2066	Belongs to the glutaminase family
E3160_13465	COG1012	belongs to the aldehyde dehydrogenase family
E3160_13470	COG0583	DNA-binding transcription factor activity
E3160_13485	COG2814	Major facilitator Superfamily
E3160_13495	COG1846	Transcriptional regulator
E3160_13500	COG4977	sequence-specific DNA binding
E3160_13510	COG0697	spore germination
E3160_13515	COG2814	Major facilitator Superfamily
E3160_13535	COG3706	GGDEF domain
E3160_13540	COG3111	PFAM Bacterial OB fold (BOF) protein
E3160_13545	COG1546	Belongs to the CinA family
E3160_13550	COG0339	signal peptide processing
E3160_13555	COG4221	oxidoreductase activity
E3160_13560	COG1802	Transcriptional regulator
E3160_13570	COG0246	Mannitol dehydrogenase
E3160_13575	COG0477	Major facilitator Superfamily
E3160_13585	COG3328	transposase activity
E3160_13715	COG3772	lysozyme
E3160_13775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_13780	COG1403	HNH endonuclease
E3160_13815	COG1846	Transcriptional regulator
E3160_13845	COG1396	sequence-specific DNA binding
E3160_13890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_13900	COG0582	viral genome integration into host DNA
E3160_13955	COG3436	PFAM IS66 Orf2 family protein
E3160_13960	COG4372	Transposase
E3160_14010	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_14145	COG3772	lysozyme
E3160_14200	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_14205	COG1403	HNH endonuclease
E3160_14235	COG1846	Transcriptional regulator
E3160_14240	COG1484	DNA-dependent DNA replication
E3160_14245	COG1846	Transcriptional regulator
E3160_14300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_14440	COG1030	water channel activity
E3160_14460	COG4220	transposase activity
E3160_14495	COG3772	lysozyme
E3160_14535	COG2207	Transcriptional regulator
E3160_14550	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_14555	COG1403	HNH endonuclease
E3160_14565	COG3111	PFAM Bacterial OB fold (BOF) protein
E3160_14600	COG0582	viral genome integration into host DNA
E3160_14610	COG1063	alcohol dehydrogenase
E3160_14615	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_14630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3160_14645	COG0243	molybdopterin cofactor binding
E3160_14650	COG0243	molybdopterin cofactor binding
E3160_14655	COG0437	4 iron, 4 sulfur cluster binding
E3160_14660	COG3302	dmso reductase anchor subunit
E3160_14665	COG3381	protein complex oligomerization
E3160_14675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3160_14680	COG1940	carbohydrate kinase activity
E3160_14685	COG0583	DNA-binding transcription factor activity
E3160_14690	COG2814	Major facilitator Superfamily
E3160_14705	COG3591	Belongs to the peptidase S1B family
E3160_14725	COG0628	permease
E3160_14730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E3160_14735	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E3160_14745	COG0531	amino acid
E3160_14755	COG3136	membrane protein required for alginate biosynthesis
E3160_14760	COG0745	RESPONSE REGULATOR receiver
E3160_14765	COG2205	protein histidine kinase activity
E3160_14775	COG0114	fumarate hydratase activity
E3160_14780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_14780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_14785	COG1482	cell wall glycoprotein biosynthetic process
E3160_14790	COG5339	Protein conserved in bacteria
E3160_14805	COG3250	beta-galactosidase activity
E3160_14810	COG1309	transcriptional regulator
E3160_14815	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_14820	COG1609	Transcriptional regulator
E3160_14825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_14825	COG1263	PTS System
E3160_14830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3160_14840	COG0673	inositol 2-dehydrogenase activity
E3160_14880	COG4659	FMN binding
E3160_14890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3160_14895	COG3104	oligopeptide transport
E3160_14900	COG0625	glutathione transferase activity
E3160_14905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E3160_14920	COG3895	Periplasmic Protein
E3160_14930	COG3133	Outer membrane lipoprotein
E3160_14945	COG1566	PFAM secretion protein HlyD family protein
E3160_14950	COG1289	transmembrane transporter activity
E3160_14955	COG2032	superoxide dismutase activity
E3160_14960	COG4989	oxidoreductase activity
E3160_14965	COG3313	Fe-S protein
E3160_14970	COG1309	transcriptional regulator
E3160_14975	COG1902	pentaerythritol trinitrate reductase activity
E3160_14980	COG0346	lactoylglutathione lyase activity
E3160_14990	COG1201	RNA secondary structure unwinding
E3160_14995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E3160_15000	COG0791	NLP P60 protein
E3160_15005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3160_15010	COG2814	Major facilitator Superfamily
E3160_15025	COG0583	DNA-binding transcription factor activity
E3160_15030	COG2814	Major facilitator Superfamily
E3160_15035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3160_15040	COG0307	riboflavin synthase, alpha
E3160_15050	COG3468	outer membrane autotransporter barrel domain protein
E3160_15075	COG4529	Protein conserved in bacteria
E3160_15085	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
E3160_15090	COG0437	4 iron, 4 sulfur cluster binding
E3160_15100	COG2414	aldehyde ferredoxin oxidoreductase
E3160_15105	COG0437	4 iron, 4 sulfur cluster binding
E3160_15115	COG0469	pyruvate kinase activity
E3160_15120	COG4238	major outer membrane lipoprotein
E3160_15125	COG1376	ErfK ybiS ycfS ynhG family protein
E3160_15140	COG0719	Fe-S assembly protein
E3160_15145	COG0396	ATPase activity
E3160_15150	COG0719	Fe-S assembly protein
E3160_15155	COG0316	Belongs to the HesB IscA family
E3160_15165	COG2050	protein possibly involved in aromatic compounds catabolism
E3160_15170	COG0247	lactate metabolic process
E3160_15170	COG0277	FAD linked oxidase domain protein
E3160_15175	COG0628	permease
E3160_15190	COG0738	Major facilitator superfamily
E3160_15195	COG2271	Major facilitator Superfamily
E3160_15210	COG4670	ketone body catabolic process
E3160_15215	COG1960	acyl-CoA dehydrogenase activity
E3160_15220	COG1917	Cupin 2, conserved barrel domain protein
E3160_15220	COG2207	Transcriptional regulator
E3160_15225	COG2086	electron transfer activity
E3160_15230	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E3160_15235	COG0644	oxidoreductase
E3160_15240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3160_15245	COG0318	PFAM AMP-dependent synthetase and ligase
E3160_15250	COG0574	Belongs to the PEP-utilizing enzyme family
E3160_15250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3160_15260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3160_15265	COG4256	Hemin uptake protein
E3160_15275	COG2200	EAL domain
E3160_15280	COG0791	NLP P60 protein
E3160_15290	COG0386	Belongs to the glutathione peroxidase family
E3160_15305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3160_15305	COG0072	phenylalanine-tRNA ligase activity
E3160_15350	COG3137	Salt-induced outer membrane protein
E3160_15355	COG1105	Belongs to the carbohydrate kinase PfkB family
E3160_15365	COG3001	Fructosamine kinase
E3160_15375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3160_15380	COG1988	membrane-bound metal-dependent
E3160_15400	COG0753	catalase activity
E3160_15410	COG1486	melibiose metabolic process
E3160_15415	COG1917	Cupin 2, conserved barrel domain protein
E3160_15415	COG2169	Transcriptional regulator
E3160_15420	COG1447	Phosphotransferase system cellobiose-specific component IIA
E3160_15425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3160_15430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3160_15440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3160_15450	COG0322	excinuclease ABC activity
E3160_15460	COG3678	ATP-independent chaperone mediated protein folding
E3160_15490	COG0708	Exodeoxyribonuclease III
E3160_15495	COG0398	Pfam SNARE associated Golgi protein
E3160_15505	COG0398	Pfam SNARE associated Golgi protein
E3160_15510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3160_15515	COG4134	Bacterial extracellular solute-binding protein
E3160_15520	COG4135	transport system, permease component
E3160_15525	COG4136	ATPase activity
E3160_15530	COG2897	thiosulfate sulfurtransferase activity
E3160_15535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E3160_15540	COG0494	nUDIX hydrolase
E3160_15550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E3160_15560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3160_15565	COG0709	Synthesizes selenophosphate from selenide and ATP
E3160_15570	COG0778	Nitroreductase
E3160_15575	COG0616	signal peptide processing
E3160_15585	COG0252	asparaginase activity
E3160_15590	COG1335	isochorismatase
E3160_15595	COG2814	Major facilitator Superfamily
E3160_15600	COG1349	DNA-binding transcription factor activity
E3160_15605	COG0667	Aldo Keto reductase
E3160_15610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_15615	COG0191	fructose-bisphosphate aldolase activity
E3160_15620	COG1063	alcohol dehydrogenase
E3160_15625	COG2271	Major facilitator Superfamily
E3160_15630	COG1063	alcohol dehydrogenase
E3160_15635	COG3139	Protein of unknown function (DUF1315)
E3160_15645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3160_15650	COG0676	glucose-6-phosphate 1-epimerase activity
E3160_15655	COG0656	L-ascorbic acid biosynthetic process
E3160_15660	COG3713	MltA-interacting MipA family protein
E3160_15665	COG2766	serine protein kinase
E3160_15675	COG2199	diguanylate cyclase activity
E3160_15680	COG2199	diguanylate cyclase activity
E3160_15685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3160_15700	COG2207	Transcriptional regulator
E3160_15705	COG2807	transmembrane transport
E3160_15710	COG3189	MarR family transcriptional regulator
E3160_15715	COG3042	response to heat
E3160_15720	COG2199	diguanylate cyclase activity
E3160_15720	COG2203	Gaf domain
E3160_15735	COG2261	transglycosylase associated protein
E3160_15745	COG3615	Tellurite resistance protein tehB
E3160_15750	COG1280	lysine exporter protein (LysE YggA)
E3160_15755	COG0583	DNA-binding transcription factor activity
E3160_15760	COG0473	3-isopropylmalate dehydrogenase activity
E3160_15765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3160_15770	COG4638	Rieske (2fe-2S)
E3160_15775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3160_15780	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E3160_15785	COG0318	PFAM AMP-dependent synthetase and ligase
E3160_15790	COG3065	identical protein binding
E3160_15795	COG1214	PFAM Peptidase M22, glycoprotease
E3160_15800	COG1199	ATP-dependent helicase activity
E3160_15805	COG0251	oxidation-reduction process
E3160_15820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3160_15830	COG1760	l-serine dehydratase
E3160_15835	COG2200	EAL domain
E3160_15840	COG1253	flavin adenine dinucleotide binding
E3160_15845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_15845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_15850	COG3715	PTS system
E3160_15855	COG3716	PTS system mannose fructose sorbose family IID component
E3160_15870	COG2226	methyltransferase
E3160_15900	COG1414	Transcriptional regulator
E3160_15905	COG2814	Major facilitator Superfamily
E3160_15915	COG0793	Belongs to the peptidase S41A family
E3160_15925	COG1956	GAF domain-containing protein
E3160_15930	COG2995	paraquat-inducible protein a
E3160_15935	COG3008	intermembrane lipid transfer
E3160_15955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E3160_15965	COG1276	copper resistance
E3160_15970	COG2372	response to copper ion
E3160_15980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3160_15985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_15990	COG1770	oligopeptidase
E3160_15995	COG2979	Protein of unknown function (DUF533)
E3160_16005	COG3141	response to X-ray
E3160_16010	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E3160_16015	COG0800	Aldolase
E3160_16020	COG0129	dihydroxy-acid dehydratase activity
E3160_16025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3160_16030	COG1737	Transcriptional regulator
E3160_16035	COG0469	pyruvate kinase activity
E3160_16040	COG1560	Kdo2-lipid A biosynthetic process
E3160_16045	COG0739	heme binding
E3160_16050	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E3160_16060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3160_16090	COG0217	transcriptional regulatory protein
E3160_16095	COG0494	nUDIX hydrolase
E3160_16105	COG1335	isochorismatase
E3160_16110	COG1801	Protein of unknown function DUF72
E3160_16115	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E3160_16130	COG0243	molybdopterin cofactor binding
E3160_16135	COG3005	denitrification pathway
E3160_16145	COG3102	Protein conserved in bacteria
E3160_16155	COG3755	Protein conserved in bacteria
E3160_16165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E3160_16170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E3160_16180	COG0745	RESPONSE REGULATOR receiver
E3160_16185	COG2201	protein-glutamate methylesterase activity
E3160_16190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E3160_16195	COG0840	transmembrane signaling receptor activity
E3160_16200	COG0840	transmembrane signaling receptor activity
E3160_16205	COG0835	chemotaxis
E3160_16210	COG2198	Histidine kinase
E3160_16210	COG0643	Histidine kinase
E3160_16215	COG1360	Flagellar Motor Protein
E3160_16220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E3160_16235	COG0589	response to stress
E3160_16245	COG1877	trehalose-phosphatase activity
E3160_16250	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_16255	COG1129	ABC transporter
E3160_16260	COG1879	ABC-type sugar transport system periplasmic component
E3160_16265	COG1528	Iron-storage protein
E3160_16285	COG1528	Iron-storage protein
E3160_16295	COG0814	amino acid
E3160_16300	COG3012	SEC-C Motif Domain Protein
E3160_16300	COG3318	Belongs to the UPF0149 family
E3160_16305	COG4974	Belongs to the 'phage' integrase family
E3160_16410	COG4695	Portal protein
E3160_16490	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_16490	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_16500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3160_16585	COG2197	response regulator
E3160_16605	COG2197	response regulator
E3160_16635	COG1191	sigma factor activity
E3160_16645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
E3160_16650	COG1516	flagellar protein fliS
E3160_16660	COG0366	Alpha amylase catalytic
E3160_16670	COG2391	methyltransferase activity
E3160_16675	COG0425	Belongs to the sulfur carrier protein TusA family
E3160_16680	COG2135	peptidase activity
E3160_16685	COG0454	-acetyltransferase
E3160_16700	COG0454	-acetyltransferase
E3160_16720	COG1766	The M ring may be actively involved in energy transduction
E3160_16725	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3160_16730	COG1317	bacterial-type flagellum organization
E3160_16735	COG1157	protein secretion by the type III secretion system
E3160_16740	COG2882	bacterial-type flagellum organization
E3160_16745	COG3144	bacterial-type flagellum assembly
E3160_16750	COG1580	Controls the rotational direction of flagella during chemotaxis
E3160_16755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3160_16760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3160_16765	COG3190	flagellar
E3160_16770	COG1338	Plays a role in the flagellum-specific transport system
E3160_16775	COG1987	bacterial-type flagellum assembly
E3160_16780	COG1684	flagellar biosynthetic protein fliR
E3160_16785	COG2197	response regulator
E3160_16810	COG3706	GGDEF domain
E3160_16815	COG5475	Uncharacterized small protein (DUF2158)
E3160_16820	COG2354	Protein conserved in bacteria
E3160_16825	COG0697	spore germination
E3160_16830	COG3727	T/G mismatch-specific endonuclease activity
E3160_16835	COG0270	DNA (cytosine-5-)-methyltransferase activity
E3160_16840	COG1418	mRNA catabolic process
E3160_16855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3160_16880	COG2205	protein histidine kinase activity
E3160_16885	COG0745	RESPONSE REGULATOR receiver
E3160_16890	COG2351	hydroxyisourate hydrolase activity
E3160_16905	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3160_16910	COG3038	cytochrome b561
E3160_16935	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_16950	COG2032	superoxide dismutase activity
E3160_17030	COG4220	transposase activity
E3160_17065	COG3772	lysozyme
E3160_17120	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_17125	COG1403	HNH endonuclease
E3160_17175	COG1846	Transcriptional regulator
E3160_17220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_17265	COG0477	Major facilitator Superfamily
E3160_17270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E3160_17275	COG0217	transcriptional regulatory protein
E3160_17295	COG0583	DNA-binding transcription factor activity
E3160_17300	COG0583	DNA-binding transcription factor activity
E3160_17310	COG1376	ErfK ybiS ycfS ynhG family protein
E3160_17325	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
E3160_17340	COG3436	PFAM IS66 Orf2 family protein
E3160_17345	COG4372	Transposase
E3160_17360	COG4771	TonB-dependent receptor
E3160_17505	COG2003	Belongs to the UPF0758 family
E3160_17540	COG4917	ethanolamine utilization protein
E3160_17550	COG1289	transmembrane transporter activity
E3160_17560	COG1686	Belongs to the peptidase S11 family
E3160_17565	COG2925	Exonuclease
E3160_17570	COG0425	Belongs to the sulfur carrier protein TusA family
E3160_17575	COG2391	methyltransferase activity
E3160_17580	COG0531	amino acid
E3160_17590	COG0583	DNA-binding transcription factor activity
E3160_17595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3160_17610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E3160_17620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3160_17620	COG0131	Imidazoleglycerol-phosphate dehydratase
E3160_17625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E3160_17655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E3160_17660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E3160_17675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3160_17680	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E3160_17680	COG0662	Cupin 2, conserved barrel domain protein
E3160_17685	COG1051	belongs to the nudix hydrolase family
E3160_17690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3160_17695	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3160_17705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3160_17730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3160_17735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3160_17745	COG0438	transferase activity, transferring glycosyl groups
E3160_17750	COG2327	Polysaccharide pyruvyl transferase
E3160_17755	COG2244	polysaccharide biosynthetic process
E3160_17760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3160_17765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3160_17770	COG0662	Cupin 2, conserved barrel domain protein
E3160_17770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E3160_17775	COG0297	glycogen (starch) synthase activity
E3160_17780	COG1051	belongs to the nudix hydrolase family
E3160_17785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3160_17790	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3160_17795	COG0110	maltose O-acetyltransferase activity
E3160_17800	COG1216	Glycosyl transferase, family 2
E3160_17810	COG0438	transferase activity, transferring glycosyl groups
E3160_17815	COG1045	serine acetyltransferase
E3160_17820	COG0463	Glycosyl transferase, family 2
E3160_17825	COG3206	protein involved in exopolysaccharide biosynthesis
E3160_17825	COG0489	protein tyrosine kinase activity
E3160_17830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E3160_17835	COG1596	polysaccharide export
E3160_17840	COG1253	flavin adenine dinucleotide binding
E3160_17855	COG2982	Protein involved in outer membrane biogenesis
E3160_17865	COG0572	uridine kinase
E3160_17875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E3160_17880	COG0443	Heat shock 70 kDa protein
E3160_17885	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
E3160_17890	COG0631	protein serine/threonine phosphatase activity
E3160_17895	COG4245	von Willebrand factor, type A
E3160_17920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_17935	COG2205	protein histidine kinase activity
E3160_17940	COG0745	RESPONSE REGULATOR receiver
E3160_17945	COG3422	double-strand break repair
E3160_17975	COG1063	alcohol dehydrogenase
E3160_17980	COG3775	system Galactitol-specific IIC component
E3160_17985	COG3414	Phosphotransferase system galactitol-specific IIB component
E3160_17990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_18005	COG1830	Aldolase
E3160_18010	COG2211	Major facilitator Superfamily
E3160_18015	COG1397	ADP-ribosylglycohydrolase
E3160_18020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_18025	COG2188	Transcriptional regulator
E3160_18030	COG3757	hydrolase, family 25
E3160_18035	COG0351	phosphomethylpyrimidine kinase
E3160_18070	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E3160_18075	COG5455	response to cobalt ion
E3160_18080	COG3539	Fimbrial protein
E3160_18085	COG3188	usher protein
E3160_18090	COG3121	Chaperone
E3160_18095	COG3539	Fimbrial protein
E3160_18105	COG0489	protein tyrosine kinase activity
E3160_18130	COG3831	ATPase activity
E3160_18135	COG3831	ATPase activity
E3160_18140	COG3831	ATPase activity
E3160_18150	COG0714	Associated with various cellular activities
E3160_18155	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E3160_18160	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E3160_18165	COG3552	Protein containing von Willebrand factor type A (VWA) domain
E3160_18170	COG4715	Zinc finger, swim domain protein
E3160_18175	COG4808	Protein conserved in bacteria
E3160_18180	COG4807	Protein conserved in bacteria
E3160_18185	COG3279	Response regulator of the LytR AlgR family
E3160_18190	COG3275	phosphorelay sensor kinase activity
E3160_18230	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3160_18250	COG3436	PFAM IS66 Orf2 family protein
E3160_18255	COG4372	Transposase
E3160_18375	COG3772	lysozyme
E3160_18455	COG1403	HNH endonuclease
E3160_18465	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3160_18475	COG4725	Belongs to the MT-A70-like family
E3160_18485	COG1846	Transcriptional regulator
E3160_18495	COG3646	Phage regulatory protein
E3160_18530	COG5532	Uncharacterized conserved protein (DUF2303)
E3160_18535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E3160_18565	COG0582	viral genome integration into host DNA
E3160_18570	COG0789	Transcriptional regulator
E3160_18580	COG1174	glycine betaine transport
E3160_18585	COG1125	glycine betaine transport
E3160_18590	COG1174	glycine betaine transport
E3160_18595	COG1732	Glycine betaine
E3160_18600	COG1472	Belongs to the glycosyl hydrolase 3 family
E3160_18605	COG0277	FAD linked oxidase domain protein
E3160_18610	COG1686	Belongs to the peptidase S11 family
E3160_18620	COG0586	Pfam SNARE associated Golgi protein
E3160_18625	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_18630	COG1538	Outer membrane efflux protein
E3160_18640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3160_18645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3160_18650	COG0625	glutathione transferase activity
E3160_18665	COG2271	Major facilitator Superfamily
E3160_18680	COG1346	cytolysis
E3160_18690	COG2949	membrane
E3160_18700	COG0493	'glutamate synthase
E3160_18705	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E3160_18705	COG0167	dihydroorotate dehydrogenase activity
E3160_18710	COG4211	Belongs to the binding-protein-dependent transport system permease family
E3160_18715	COG1129	ABC transporter
E3160_18720	COG1879	ABC-type sugar transport system periplasmic component
E3160_18725	COG1609	Transcriptional regulator
E3160_18730	COG2311	Membrane
E3160_18740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3160_18745	COG4771	TonB-dependent receptor
E3160_18755	COG0833	amino acid
E3160_18760	COG0583	DNA-binding transcription factor activity
E3160_18765	COG2855	membrane
E3160_18775	COG1522	sequence-specific DNA binding
E3160_18775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_18780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3160_18790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3160_18795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3160_18800	COG2313	pseudouridylate synthase activity
E3160_18805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_18810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_18810	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3160_18810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_18815	COG1105	Belongs to the carbohydrate kinase PfkB family
E3160_18820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_18820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_18825	COG2814	Major facilitator Superfamily
E3160_18840	COG0246	Mannitol dehydrogenase
E3160_18845	COG0523	cobalamin synthesis protein
E3160_18850	COG0671	phosphoesterase, PA-phosphatase related
E3160_18855	COG0791	NLP P60 protein
E3160_18865	COG4166	transmembrane transport
E3160_18870	COG4174	ABC transporter (Permease)
E3160_18875	COG4239	(ABC) transporter, permease
E3160_18880	COG4172	Belongs to the ABC transporter superfamily
E3160_18890	COG2814	Major facilitator Superfamily
E3160_18895	COG1187	pseudouridine synthase activity
E3160_18900	COG1061	Type III restriction enzyme res subunit
E3160_18920	COG3083	sulfuric ester hydrolase activity
E3160_18930	COG3468	outer membrane autotransporter barrel domain protein
E3160_18935	COG2197	response regulator
E3160_18940	COG3088	subunit of a heme lyase
E3160_18940	COG4235	cytochrome complex assembly
E3160_18945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3160_18950	COG1138	Cytochrome C-type biogenesis protein
E3160_18960	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3160_18965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3160_18970	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3160_18975	COG4133	protoheme IX ABC transporter activity
E3160_18980	COG3005	denitrification pathway
E3160_18985	COG3043	anaerobic respiration
E3160_18990	COG0348	domain, Protein
E3160_18995	COG0437	4 iron, 4 sulfur cluster binding
E3160_19005	COG3062	negative regulation of establishment of protein localization
E3160_19010	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_19010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_19025	COG4615	Cyclic peptide transporter
E3160_19030	COG3145	DNA-N1-methyladenine dioxygenase activity
E3160_19035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3160_19035	COG2169	Transcriptional regulator
E3160_19040	COG1477	protein flavinylation
E3160_19045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3160_19050	COG0642	Histidine kinase
E3160_19050	COG2198	Histidine kinase
E3160_19055	COG2197	response regulator
E3160_19060	COG0784	Response regulator, receiver
E3160_19060	COG2205	protein histidine kinase activity
E3160_19065	COG4676	Protein conserved in bacteria
E3160_19075	COG2373	Large extracellular alpha-helical protein
E3160_19080	COG3234	Protein of unknown function (DUF1175)
E3160_19085	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
E3160_19090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3160_19100	COG3468	outer membrane autotransporter barrel domain protein
E3160_19105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3160_19110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3160_19115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3160_19120	COG3642	lipopolysaccharide core region biosynthetic process
E3160_19125	COG2814	Major facilitator Superfamily
E3160_19130	COG0583	DNA-binding transcription factor activity
E3160_19140	COG0584	glycerophosphoryl diester phosphodiesterase
E3160_19145	COG2271	Major facilitator Superfamily
E3160_19150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3160_19160	COG0247	lactate metabolic process
E3160_19165	COG5464	transposase or invertase
E3160_19170	COG3836	Belongs to the HpcH HpaI aldolase family
E3160_19175	COG2271	Major facilitator Superfamily
E3160_19180	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_19185	COG1414	Transcriptional regulator
E3160_19205	COG0406	alpha-ribazole phosphatase activity
E3160_19250	COG0318	PFAM AMP-dependent synthetase and ligase
E3160_19260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E3160_19275	COG1169	isochorismate synthase
E3160_19280	COG4575	ribosome binding
E3160_19285	COG2153	protein acetylation
E3160_19295	COG5160	protein modification by small protein removal
E3160_19315	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3160_19320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3160_19330	COG0839	Belongs to the complex I subunit 6 family
E3160_19345	COG1034	ATP synthesis coupled electron transport
E3160_19350	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3160_19355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E3160_19375	COG0583	DNA-binding transcription factor activity
E3160_19380	COG0436	Aminotransferase
E3160_19390	COG0490	domain, Protein
E3160_19390	COG0471	metal ion transport
E3160_19395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3160_19410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3160_19415	COG0280	phosphate acetyltransferase
E3160_19415	COG0857	belongs to the CobB CobQ family
E3160_19420	COG1288	antiporter activity
E3160_19425	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E3160_19430	COG0622	Phosphoesterase
E3160_19450	COG0625	glutathione transferase activity
E3160_19455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3160_19460	COG1090	epimerase
E3160_19465	COG5464	transposase or invertase
E3160_19470	COG4598	ABC transporter
E3160_19475	COG4160	amino acid transport
E3160_19480	COG4215	(ABC) transporter
E3160_19485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_19490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_19495	COG0163	prenyltransferase activity
E3160_19500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E3160_19505	COG1286	toxin biosynthetic process
E3160_19510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E3160_19515	COG0285	dihydrofolate synthase activity
E3160_19525	COG0586	Pfam SNARE associated Golgi protein
E3160_19535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3160_19550	COG2814	Major facilitator Superfamily
E3160_19555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3160_19560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3160_19560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E3160_19570	COG3101	peptidyl-lysine hydroxylation
E3160_19575	COG0730	response to heat
E3160_19605	COG3539	Fimbrial protein
E3160_19610	COG3539	Fimbrial protein
E3160_19615	COG3539	Fimbrial protein
E3160_19620	COG3121	Chaperone
E3160_19625	COG3188	usher protein
E3160_19630	COG3539	Fimbrial protein
E3160_19635	COG2062	phosphohistidine phosphatase, SixA
E3160_19650	COG3691	Protein conserved in bacteria
E3160_19655	COG2067	long-chain fatty acid transport protein
E3160_19670	COG2853	Lipoprotein
E3160_19675	COG2116	formate transmembrane transporter activity
E3160_19685	COG0582	viral genome integration into host DNA
E3160_19765	COG0477	Major facilitator Superfamily
E3160_19770	COG1566	PFAM secretion protein HlyD family protein
E3160_19775	COG2197	response regulator
E3160_19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_19780	COG0784	Response regulator, receiver
E3160_19780	COG2205	protein histidine kinase activity
E3160_19780	COG2198	Histidine kinase
E3160_19785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3160_19795	COG3436	PFAM IS66 Orf2 family protein
E3160_19800	COG4372	Transposase
E3160_19805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3160_19810	COG0679	Auxin Efflux Carrier
E3160_19815	COG0028	Belongs to the TPP enzyme family
E3160_19840	COG1560	Kdo2-lipid A biosynthetic process
E3160_19850	COG0436	Aminotransferase
E3160_19860	COG3279	Response regulator of the LytR AlgR family
E3160_19865	COG2207	Transcriptional regulator
E3160_19870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_19870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_19870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3160_19875	COG1363	Peptidase, m42
E3160_19880	COG0006	proline dipeptidase activity
E3160_19885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_19890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3160_19915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3160_19920	COG2200	EAL domain
E3160_19920	COG2199	diguanylate cyclase activity
E3160_19935	COG3415	Transposase
E3160_19940	COG3415	Transposase
E3160_19945	COG0675	Transposase, IS605 OrfB family
E3160_19985	COG0583	DNA-binding transcription factor activity
E3160_19990	COG0385	Bile acid
E3160_19995	COG3530	Putative quorum-sensing-regulated virulence factor
E3160_20015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3160_20020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_20025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3160_20030	COG2190	(PTS) system
E3160_20045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3160_20050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E3160_20055	COG4208	sulfate ABC transporter
E3160_20060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
E3160_20065	COG4150	thiosulfate binding
E3160_20070	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_20085	COG1263	PTS System
E3160_20085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_20090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3160_20095	COG2837	iron assimilation
E3160_20115	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3160_20125	COG2207	Transcriptional regulator
E3160_20130	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3160_20135	COG4816	utilization protein
E3160_20145	COG4303	Ethanolamine ammonia lyase large subunit
E3160_20150	COG0582	viral genome integration into host DNA
E3160_20220	COG4819	ethanolamine utilization protein
E3160_20225	COG3192	ethanolamine utilization protein
E3160_20230	COG1454	alcohol dehydrogenase
E3160_20235	COG4820	ethanolamine utilization protein (EutJ)
E3160_20240	COG1012	belongs to the aldehyde dehydrogenase family
E3160_20245	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E3160_20250	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3160_20255	COG0280	phosphate acetyltransferase
E3160_20260	COG4812	Cobalamin adenosyltransferase
E3160_20270	COG4917	ethanolamine utilization protein
E3160_20275	COG4810	utilization protein
E3160_20280	COG0280	phosphate acetyltransferase
E3160_20280	COG0281	malic enzyme
E3160_20285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3160_20290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3160_20295	COG5342	invasion associated locus B
E3160_20305	COG0493	'glutamate synthase
E3160_20305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_20310	COG3850	Histidine kinase
E3160_20315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_20330	COG1393	Belongs to the ArsC family
E3160_20345	COG0400	carboxylic ester hydrolase activity
E3160_20355	COG2321	neutral zinc metallopeptidase
E3160_20365	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E3160_20375	COG2716	regulation of RNA biosynthetic process
E3160_20380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3160_20385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_20390	COG0651	ATP synthesis coupled electron transport
E3160_20395	COG0650	Formate hydrogenlyase subunit 4
E3160_20400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3160_20405	COG4237	Hydrogenase 4 membrane
E3160_20410	COG0651	ATP synthesis coupled electron transport
E3160_20415	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3160_20415	COG3261	NADH dehydrogenase
E3160_20420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3160_20425	COG3260	NADH ubiquinone oxidoreductase 20
E3160_20435	COG3604	Transcriptional regulator
E3160_20440	COG2116	formate transmembrane transporter activity
E3160_20445	COG0628	permease
E3160_20450	COG4783	chaperone-mediated protein folding
E3160_20455	COG1393	Belongs to the ArsC family
E3160_20465	COG2233	PERMEase
E3160_20480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E3160_20485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E3160_20490	COG0248	Ppx GppA phosphatase
E3160_20495	COG2200	EAL domain
E3160_20505	COG3133	Outer membrane lipoprotein
E3160_20520	COG0516	GMP reductase activity
E3160_20520	COG0517	IMP dehydrogenase activity
E3160_20530	COG1645	bacterial-type flagellum-dependent swarming motility
E3160_20545	COG2976	Protein conserved in bacteria
E3160_20580	COG3302	dmso reductase anchor subunit
E3160_20585	COG0437	4 iron, 4 sulfur cluster binding
E3160_20590	COG0243	molybdopterin cofactor binding
E3160_20595	COG4953	penicillin-binding protein 1C
E3160_20600	COG2373	Large extracellular alpha-helical protein
E3160_20605	COG2897	thiosulfate sulfurtransferase activity
E3160_20620	COG2975	iron-sulfur cluster assembly
E3160_20625	COG0633	Ferredoxin
E3160_20645	COG0822	iron-sulfur transferase activity
E3160_20665	COG0483	inositol monophosphate 1-phosphatase activity
E3160_20670	COG1073	alpha beta
E3160_20675	COG3711	transcriptional antiterminator
E3160_20680	COG2814	Major facilitator Superfamily
E3160_20685	COG0583	DNA-binding transcription factor activity
E3160_20690	COG4638	Rieske (2fe-2S)
E3160_20715	COG2259	Doxx family
E3160_20720	COG2017	converts alpha-aldose to the beta-anomer
E3160_20725	COG1063	alcohol dehydrogenase
E3160_20730	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3160_20735	COG1129	ABC transporter
E3160_20740	COG1879	ABC-type sugar transport system periplasmic component
E3160_20745	COG0457	Tetratricopeptide repeat
E3160_20750	COG1940	carbohydrate kinase activity
E3160_20760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3160_20760	COG1017	nitric oxide dioxygenase activity
E3160_20765	COG0347	Belongs to the P(II) protein family
E3160_20770	COG2204	response regulator
E3160_20775	COG3170	Tfp pilus assembly protein FimV
E3160_20780	COG2205	protein histidine kinase activity
E3160_20785	COG0047	phosphoribosylformylglycinamidine synthase activity
E3160_20785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3160_20790	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E3160_20795	COG0590	tRNA wobble adenosine to inosine editing
E3160_20800	COG0560	Phosphoserine phosphatase
E3160_20805	COG1737	Transcriptional regulator
E3160_20810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_20825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E3160_20845	COG0681	Belongs to the peptidase S26 family
E3160_20855	COG3086	response to oxidative stress
E3160_20860	COG3026	antisigma factor binding
E3160_20865	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
E3160_20870	COG1595	DNA-templated transcription, initiation
E3160_20880	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E3160_20885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3160_20890	COG0513	Belongs to the DEAD box helicase family
E3160_20895	COG0583	DNA-binding transcription factor activity
E3160_20900	COG1280	lysine exporter protein (LysE YggA)
E3160_20915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3160_20920	COG3118	belongs to the thioredoxin family
E3160_20930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3160_20930	COG1042	CoA-binding domain protein
E3160_20930	COG0045	succinate-CoA ligase (ADP-forming) activity
E3160_20935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3160_20940	COG5544	Lipoprotein
E3160_20945	COG0477	Major facilitator Superfamily
E3160_20970	COG0542	response to heat
E3160_20980	COG0564	pseudouridine synthase activity
E3160_20985	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3160_20990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3160_21000	COG0077	Prephenate dehydratase
E3160_21000	COG1605	Chorismate mutase
E3160_21005	COG1605	Chorismate mutase
E3160_21005	COG0287	Prephenate dehydrogenase
E3160_21010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3160_21025	COG2199	diguanylate cyclase activity
E3160_21030	COG2885	chlorophyll binding
E3160_21055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3160_21060	COG4137	Cytochrome C assembly protein
E3160_21065	COG4536	flavin adenine dinucleotide binding
E3160_21085	COG0497	DNA recombination
E3160_21090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3160_21100	COG2867	negative regulation of translational initiation
E3160_21125	COG0727	PFAM Uncharacterised protein family (UPF0153)
E3160_21315	COG3772	lysozyme
E3160_21460	COG0579	oxidoreductase
E3160_21465	COG1012	belongs to the aldehyde dehydrogenase family
E3160_21470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3160_21475	COG1113	amino acid transport
E3160_21480	COG1802	Transcriptional regulator
E3160_21485	COG1652	LysM domain
E3160_21490	COG0401	homolog of Blt101
E3160_21495	COG0640	Transcriptional regulator
E3160_21500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3160_21505	COG2916	Histone family protein nucleoid-structuring protein H-NS
E3160_21520	COG4575	ribosome binding
E3160_21530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3160_21540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3160_21550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3160_21555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3160_21565	COG4175	Glycine betaine
E3160_21570	COG4176	ABC-type proline glycine betaine transport system permease component
E3160_21575	COG2113	Glycine betaine
E3160_21580	COG2814	Major facilitator Superfamily
E3160_21585	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E3160_21595	COG1846	Transcriptional regulator
E3160_21600	COG1566	PFAM secretion protein HlyD family protein
E3160_21605	COG2814	Major facilitator Superfamily
E3160_21620	COG1238	metal cluster binding
E3160_21625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3160_21655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E3160_21660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E3160_21675	COG1546	Belongs to the CinA family
E3160_21680	COG2951	lytic endotransglycosylase activity
E3160_21685	COG3730	PTS system glucitol sorbitol-specific
E3160_21700	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_21705	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_21710	COG1349	DNA-binding transcription factor activity
E3160_21715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E3160_21715	COG0517	IMP dehydrogenase activity
E3160_21735	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E3160_21740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_21745	COG1609	Transcriptional regulator
E3160_21750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_21750	COG1263	PTS System
E3160_21755	COG2723	6-phospho-beta-galactosidase activity
E3160_21760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3160_21770	COG3260	NADH ubiquinone oxidoreductase 20
E3160_21775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3160_21780	COG3261	NADH dehydrogenase
E3160_21780	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3160_21785	COG0650	Formate hydrogenlyase subunit 4
E3160_21790	COG0651	ATP synthesis coupled electron transport
E3160_21795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_21805	COG0375	protein maturation
E3160_21810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E3160_21815	COG0298	carbon dioxide binding
E3160_21820	COG0409	Hydrogenase expression formation protein
E3160_21825	COG0309	Hydrogenase expression formation protein (HypE)
E3160_21830	COG3604	Transcriptional regulator
E3160_21845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E3160_21855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3160_21860	COG0163	prenyltransferase activity
E3160_21865	COG1846	Transcriptional regulator
E3160_21870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3160_21875	COG1388	LysM domain
E3160_21875	COG4942	peptidase
E3160_21930	COG2234	aminopeptidase activity
E3160_21935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3160_21940	COG1518	maintenance of DNA repeat elements
E3160_21955	COG1857	crispr-associated protein
E3160_21970	COG1203	CRISPR-associated helicase, Cas3
E3160_21995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3160_22000	COG0720	synthase
E3160_22005	COG0644	oxidoreductase
E3160_22010	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3160_22015	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3160_22025	COG2086	electron transfer activity
E3160_22035	COG0277	FAD linked oxidase domain protein
E3160_22040	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_22045	COG2223	nitrite transmembrane transporter activity
E3160_22050	COG1070	Carbohydrate kinase
E3160_22055	COG0602	queuosine metabolic process
E3160_22065	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E3160_22075	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E3160_22090	COG3956	TIGRFAM MazG family protein
E3160_22095	COG2337	Toxic component of a toxin-antitoxin (TA) module
E3160_22100	COG2336	PFAM SpoVT AbrB
E3160_22105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3160_22110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3160_22115	COG2205	protein histidine kinase activity
E3160_22115	COG3437	response regulator, receiver
E3160_22115	COG3850	Histidine kinase
E3160_22115	COG4999	Histidine kinase
E3160_22120	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_22125	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_22130	COG4948	Mandelate Racemase Muconate Lactonizing
E3160_22135	COG2271	Major facilitator Superfamily
E3160_22140	COG0716	FMN binding
E3160_22145	COG0564	pseudouridine synthase activity
E3160_22150	COG3098	single-species biofilm formation
E3160_22165	COG1611	Belongs to the LOG family
E3160_22170	COG0814	amino acid
E3160_22175	COG1760	l-serine dehydratase
E3160_22185	COG1454	alcohol dehydrogenase
E3160_22190	COG0235	Class ii aldolase
E3160_22195	COG0738	Major facilitator superfamily
E3160_22205	COG1070	Carbohydrate kinase
E3160_22215	COG1349	DNA-binding transcription factor activity
E3160_22225	COG2363	Small membrane protein
E3160_22230	COG0583	DNA-binding transcription factor activity
E3160_22240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3160_22245	COG2166	iron-sulfur cluster assembly
E3160_22250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3160_22255	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E3160_22275	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3160_22280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E3160_22280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E3160_22285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3160_22290	COG1074	ATP-dependent DNA helicase activity
E3160_22295	COG1025	Belongs to the peptidase M16 family
E3160_22300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3160_22305	COG4967	type IV pilus modification protein PilV
E3160_22315	COG4795	General secretion pathway protein
E3160_22320	COG2165	general secretion pathway protein
E3160_22335	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
E3160_22355	COG0861	Integral membrane protein TerC family
E3160_22365	COG0667	Aldo Keto reductase
E3160_22380	COG1609	Transcriptional regulator
E3160_22390	COG0583	DNA-binding transcription factor activity
E3160_22395	COG1794	racemase activity, acting on amino acids and derivatives
E3160_22400	COG2814	Major facilitator Superfamily
E3160_22405	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_22415	COG0183	Belongs to the thiolase family
E3160_22420	COG0814	amino acid
E3160_22425	COG2771	luxR family
E3160_22430	COG3710	Transcriptional regulator
E3160_22455	COG0457	Tetratricopeptide repeat
E3160_22465	COG3710	Transcriptional regulator
E3160_22465	COG0457	Tetratricopeptide repeat
E3160_22480	COG3436	PFAM IS66 Orf2 family protein
E3160_22485	COG4372	Transposase
E3160_22490	COG0741	lytic transglycosylase activity
E3160_22495	COG2197	response regulator
E3160_22610	COG2207	Transcriptional regulator
E3160_22620	COG3387	PFAM Glycoside hydrolase 15-related
E3160_22630	COG4942	peptidase
E3160_22635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3160_22640	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E3160_22645	COG2080	2 iron, 2 sulfur cluster binding
E3160_22655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E3160_22660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3160_22665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3160_22675	COG0549	Belongs to the carbamate kinase family
E3160_22680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E3160_22680	COG3608	succinylglutamate desuccinylase aspartoacylase
E3160_22685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E3160_22690	COG2068	MobA-Related Protein
E3160_22695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_22695	COG0493	'glutamate synthase
E3160_22700	COG0402	S-adenosylhomocysteine deaminase activity
E3160_22705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E3160_22710	COG2080	2 iron, 2 sulfur cluster binding
E3160_22710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3160_22715	COG2233	PERMEase
E3160_22720	COG0402	S-adenosylhomocysteine deaminase activity
E3160_22725	COG2252	PERMEase
E3160_22740	COG2233	PERMEase
E3160_22760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3160_22770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3160_22775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3160_22780	COG4974	Belongs to the 'phage' integrase family
E3160_22785	COG0716	FMN binding
E3160_22795	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E3160_22805	COG1272	protein, Hemolysin III
E3160_22815	COG2723	6-phospho-beta-galactosidase activity
E3160_22840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3160_22845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3160_22850	COG0006	proline dipeptidase activity
E3160_22870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3160_22885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3160_22900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3160_22900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3160_22905	COG1703	isobutyryl-CoA mutase activity
E3160_22910	COG1024	Enoyl-CoA hydratase
E3160_22915	COG0427	acetyl-CoA hydrolase
E3160_22920	COG0583	DNA-binding transcription factor activity
E3160_22925	COG0583	DNA-binding transcription factor activity
E3160_22930	COG2968	Membrane
E3160_22940	COG0668	transmembrane transport
E3160_22945	COG0191	fructose-bisphosphate aldolase activity
E3160_22950	COG0126	phosphoglycerate kinase activity
E3160_22975	COG1122	ATPase activity
E3160_22980	COG1122	ATPase activity
E3160_22985	COG1072	(Pantothenic acid kinase))
E3160_22995	COG1494	fructose-1,6-bisphosphatase
E3160_23000	COG1063	alcohol dehydrogenase
E3160_23005	COG2213	PTS system mannitol-specific
E3160_23010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_23015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3160_23020	COG0501	Belongs to the peptidase M48B family
E3160_23035	COG1166	arginine decarboxylase activity
E3160_23060	COG2814	Major facilitator Superfamily
E3160_23070	COG2356	endonuclease I
E3160_23075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3160_23080	COG0189	ligase activity
E3160_23095	COG2805	Type II/IV secretion system protein
E3160_23100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3160_23105	COG0762	integral membrane protein
E3160_23115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E3160_23120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3160_23130	COG0252	asparaginase activity
E3160_23140	COG3171	Protein conserved in bacteria
E3160_23150	COG1194	a g-specific adenine glycosylase
E3160_23165	COG2211	Major facilitator Superfamily
E3160_23170	COG1982	Orn Lys Arg decarboxylase major
E3160_23175	COG1811	Na channel or pump
E3160_23185	COG0582	viral genome integration into host DNA
E3160_23205	COG3436	PFAM IS66 Orf2 family protein
E3160_23280	COG3436	PFAM IS66 Orf2 family protein
E3160_23285	COG4372	Transposase
E3160_23295	COG3436	PFAM IS66 Orf2 family protein
E3160_23320	COG0754	glutathionylspermidine amidase activity
E3160_23325	COG0625	glutathione transferase activity
E3160_23330	COG0298	carbon dioxide binding
E3160_23335	COG0375	protein maturation
E3160_23340	COG1773	rubredoxin
E3160_23345	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3160_23350	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3160_23355	COG5557	Pfam Polysulphide reductase, NrfD
E3160_23360	COG0437	4 iron, 4 sulfur cluster binding
E3160_23365	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3160_23380	COG0667	Aldo Keto reductase
E3160_23390	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_23395	COG0848	biopolymer transport protein
E3160_23400	COG0811	peptide transport
E3160_23405	COG0626	cystathionine gamma-synthase activity
E3160_23410	COG0586	Pfam SNARE associated Golgi protein
E3160_23415	COG2207	Transcriptional regulator
E3160_23420	COG1979	alcohol dehydrogenase
E3160_23425	COG0656	L-ascorbic acid biosynthetic process
E3160_23435	COG4238	major outer membrane lipoprotein
E3160_23440	COG1032	radical SAM domain protein
E3160_23445	COG2132	Multicopper oxidase
E3160_23450	COG0204	Acyl-transferase
E3160_23455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3160_23460	COG4166	transmembrane transport
E3160_23465	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3160_23470	COG3111	PFAM Bacterial OB fold (BOF) protein
E3160_23475	COG0745	RESPONSE REGULATOR receiver
E3160_23480	COG0642	Histidine kinase
E3160_23485	COG2249	NAD(P)H dehydrogenase (quinone) activity
E3160_23490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E3160_23495	COG1737	Transcriptional regulator
E3160_23505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_23510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_23515	COG1120	ATPase activity
E3160_23520	COG4774	siderophore transport
E3160_23525	COG0187	DNA topoisomerase II activity
E3160_23530	COG3150	esterase
E3160_23535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3160_23540	COG3151	Protein conserved in bacteria
E3160_23545	COG0494	nUDIX hydrolase
E3160_23550	COG1538	Outer membrane efflux protein
E3160_23560	COG0754	glutathionylspermidine amidase activity
E3160_23565	COG3384	dioxygenase
E3160_23590	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3160_23595	COG2268	Band 7 protein
E3160_23620	COG3025	triphosphatase activity
E3160_23625	COG4991	sh3 domain protein
E3160_23640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3160_23650	COG0583	DNA-binding transcription factor activity
E3160_23655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_23660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3160_23665	COG0471	metal ion transport
E3160_23675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E3160_23680	COG0358	DNA primase activity
E3160_23685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3160_23700	COG2375	cellular response to nickel ion
E3160_23705	COG1695	Transcriptional regulator
E3160_23710	COG0840	transmembrane signaling receptor activity
E3160_23720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3160_23725	COG1609	Transcriptional regulator
E3160_23730	COG3250	beta-galactosidase activity
E3160_23735	COG2731	YhcH YjgK YiaL family protein
E3160_23740	COG0531	amino acid
E3160_23750	COG3408	Glycogen debranching enzyme
E3160_23750	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E3160_23755	COG0446	pyridine nucleotide-disulphide oxidoreductase
E3160_23755	COG1902	pentaerythritol trinitrate reductase activity
E3160_23760	COG5499	transcription regulator containing HTH domain
E3160_23765	COG4680	protein conserved in bacteria
E3160_23775	COG1451	nucleotide metabolic process
E3160_23780	COG2949	membrane
E3160_23785	COG0673	inositol 2-dehydrogenase activity
E3160_23790	COG0861	Integral membrane protein TerC family
E3160_23795	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
E3160_23805	COG2721	sulfolactate sulfo-lyase activity
E3160_23815	COG2271	Major facilitator Superfamily
E3160_23820	COG2186	Transcriptional regulator
E3160_23825	COG0586	Pfam SNARE associated Golgi protein
E3160_23835	COG1422	Protein of unknown function (DUF1090)
E3160_23840	COG4575	ribosome binding
E3160_23845	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E3160_23855	COG2259	Doxx family
E3160_23860	COG0435	Glutathione S-transferase
E3160_23865	COG3152	Membrane
E3160_23870	COG3152	Membrane
E3160_23875	COG0583	DNA-binding transcription factor activity
E3160_23880	COG1741	Belongs to the pirin family
E3160_23895	COG0814	amino acid
E3160_23900	COG1760	l-serine dehydratase
E3160_23905	COG0251	oxidation-reduction process
E3160_23910	COG1882	Formate acetyltransferase
E3160_23915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3160_23925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3160_23930	COG0583	DNA-binding transcription factor activity
E3160_23955	COG1929	Belongs to the glycerate kinase type-1 family
E3160_23960	COG2084	Dehydrogenase
E3160_23970	COG2271	Major facilitator Superfamily
E3160_23975	COG2721	sulfolactate sulfo-lyase activity
E3160_23980	COG2002	toxin-antitoxin pair type II binding
E3160_23990	COG1349	DNA-binding transcription factor activity
E3160_24000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_24010	COG3716	PTS system mannose fructose sorbose family IID component
E3160_24015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_24025	COG2222	sugar isomerase
E3160_24035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3160_24045	COG3716	PTS system mannose fructose sorbose family IID component
E3160_24055	COG3539	Fimbrial protein
E3160_24060	COG3121	Chaperone
E3160_24070	COG3188	usher protein
E3160_24085	COG3539	Fimbrial protein
E3160_24090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3160_24110	COG2823	Periplasmic or secreted lipoprotein
E3160_24115	COG0701	Predicted permease
E3160_24120	COG0702	epimerase
E3160_24125	COG0693	protein deglycase activity
E3160_24130	COG3787	Belongs to the UPF0306 family
E3160_24140	COG3153	acetyltransferase
E3160_24145	COG3154	lipid carrier protein
E3160_24150	COG0826	peptidase U32
E3160_24155	COG0826	peptidase U32
E3160_24160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3160_24165	COG0814	amino acid
E3160_24170	COG0513	Belongs to the DEAD box helicase family
E3160_24210	COG0195	Participates in both transcription termination and antitermination
E3160_24230	COG2194	sulfuric ester hydrolase activity
E3160_24240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3160_24250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3160_24255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3160_24265	COG1534	Rna-binding protein
E3160_24270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3160_24275	COG2027	D-alanyl-D-alanine carboxypeptidase
E3160_24285	COG0697	spore germination
E3160_24300	COG0142	geranyltranstransferase activity
E3160_24305	COG3423	Transcriptional regulator
E3160_24315	COG5007	Belongs to the BolA IbaG family
E3160_24320	COG3113	response to antibiotic
E3160_24325	COG2854	intermembrane phospholipid transfer
E3160_24330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3160_24335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3160_24340	COG1127	ABC transporter
E3160_24345	COG0530	calcium, potassium:sodium antiporter activity
E3160_24350	COG0517	IMP dehydrogenase activity
E3160_24350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E3160_24355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E3160_24360	COG3117	lipopolysaccharide transmembrane transporter activity
E3160_24365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E3160_24370	COG1137	ATPase activity
E3160_24375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E3160_24380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3160_24395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_24400	COG0515	serine threonine protein kinase
E3160_24410	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E3160_24415	COG5002	protein histidine kinase activity
E3160_24415	COG0784	Response regulator, receiver
E3160_24415	COG2198	Histidine kinase
E3160_24420	COG1242	4 iron, 4 sulfur cluster binding
E3160_24425	COG0067	glutamate synthase
E3160_24425	COG0070	glutamate synthase
E3160_24425	COG0069	glutamate synthase activity
E3160_24430	COG0493	'glutamate synthase
E3160_24440	COG2731	YhcH YjgK YiaL family protein
E3160_24475	COG2969	positive regulation of protein catabolic process
E3160_24480	COG0625	glutathione transferase activity
E3160_24500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E3160_24505	COG3105	Protein conserved in bacteria
E3160_24510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3160_24515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3160_24535	COG2732	(Barnase) inhibitor
E3160_24555	COG0583	DNA-binding transcription factor activity
E3160_24560	COG0312	modulator of DNA gyrase
E3160_24565	COG3164	Protein of unknown function
E3160_24570	COG1530	ribonuclease E activity
E3160_24575	COG0424	maF-like protein
E3160_24580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E3160_24585	COG1792	Involved in formation and maintenance of cell shape
E3160_24590	COG1077	Cell shape determining protein MreB Mrl
E3160_24600	COG2199	diguanylate cyclase activity
E3160_24600	COG2200	EAL domain
E3160_24605	COG0604	alcohol dehydrogenase
E3160_24610	COG0511	ligase activity, forming carbon-carbon bonds
E3160_24615	COG0439	Biotin carboxylase
E3160_24620	COG3924	membrane
E3160_24625	COG4145	pantothenate transmembrane transporter activity
E3160_24635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3160_24645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_24655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3160_24660	COG4597	amino acid ABC transporter
E3160_24665	COG0765	amino acid transport
E3160_24670	COG1126	abc transporter atp-binding protein
E3160_24715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3160_24730	COG0009	L-threonylcarbamoyladenylate synthase
E3160_24735	COG0551	DNA topoisomerase type I activity
E3160_24745	COG0758	DNA mediated transformation
E3160_24765	COG0569	domain protein
E3160_24775	COG3036	rescue of stalled ribosome
E3160_24780	COG0789	Transcriptional regulator
E3160_24820	COG0201	protein transport
E3160_24910	COG0089	rRNA binding
E3160_24985	COG2964	Protein conserved in bacteria
E3160_24990	COG0545	Peptidyl-prolyl cis-trans isomerase
E3160_25000	COG1047	Peptidyl-prolyl cis-trans
E3160_25005	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E3160_25020	COG0488	(ABC) transporter
E3160_25025	COG0429	hydrolase of the alpha beta-hydrolase fold
E3160_25035	COG3954	Phosphoribulokinase
E3160_25040	COG1765	OsmC-like protein
E3160_25045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3160_25050	COG1289	transmembrane transporter activity
E3160_25055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E3160_25060	COG0512	Glutamine amidotransferase of anthranilate synthase
E3160_25065	COG2184	nucleotidyltransferase activity
E3160_25075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3160_25090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3160_25095	COG2146	nitrite reductase [NAD(P)H] activity
E3160_25100	COG2116	formate transmembrane transporter activity
E3160_25115	COG0531	amino acid
E3160_25120	COG2222	sugar isomerase
E3160_25125	COG1082	Xylose isomerase domain protein TIM barrel
E3160_25130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_25135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3160_25140	COG2188	Transcriptional regulator
E3160_25145	COG0180	Tryptophanyl-tRNA synthetase
E3160_25150	COG0546	phosphoglycolate phosphatase activity
E3160_25155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3160_25160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E3160_25165	COG3266	domain, Protein
E3160_25180	COG4796	Type ii and iii secretion system protein
E3160_25195	COG3166	PFAM Fimbrial assembly family protein
E3160_25200	COG4972	Pilus assembly protein
E3160_25205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E3160_25210	COG0494	nUDIX hydrolase
E3160_25220	COG1011	Hydrolase
E3160_25225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3160_25235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3160_25245	COG2205	protein histidine kinase activity
E3160_25250	COG0745	RESPONSE REGULATOR receiver
E3160_25255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3160_25260	COG2183	response to ionizing radiation
E3160_25265	COG1918	ferrous iron import across plasma membrane
E3160_25270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E3160_25280	COG5464	transposase or invertase
E3160_25290	COG1040	competence protein
E3160_25300	COG2610	gluconate transmembrane transporter activity
E3160_25305	COG1640	4-alpha-glucanotransferase
E3160_25310	COG0058	SHG alpha-glucan phosphorylase activity
E3160_25335	COG1690	Belongs to the RtcB family
E3160_25345	COG1349	DNA-binding transcription factor activity
E3160_25360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3160_25375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3160_25380	COG0058	SHG alpha-glucan phosphorylase activity
E3160_25400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E3160_25405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3160_25410	COG2095	MarC family integral membrane protein
E3160_25430	COG0514	ATP-dependent DNA helicase (RecQ)
E3160_25435	COG2610	gluconate transmembrane transporter activity
E3160_25440	COG3265	gluconokinase activity
E3160_25445	COG1609	Transcriptional regulator
E3160_25450	COG1741	Belongs to the pirin family
E3160_25455	COG0673	inositol 2-dehydrogenase activity
E3160_25465	COG1247	-acetyltransferase
E3160_25480	COG0405	Gamma-glutamyltransferase
E3160_25490	COG0584	glycerophosphoryl diester phosphodiesterase
E3160_25495	COG3842	ATPase activity
E3160_25505	COG1175	transmembrane transport
E3160_25510	COG1653	transport
E3160_25520	COG0410	ABC transporter
E3160_25525	COG0411	ABC transporter
E3160_25530	COG4177	L-phenylalanine transmembrane transporter activity
E3160_25535	COG0559	Belongs to the binding-protein-dependent transport system permease family
E3160_25540	COG0683	leucine binding
E3160_25545	COG0456	acetyltransferase
E3160_25560	COG0683	leucine binding
E3160_25565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3160_25570	COG2177	Part of the ABC transporter FtsEX involved in
E3160_25575	COG2884	Cell division ATP-binding protein ftsE
E3160_25580	COG0552	protein localization to endoplasmic reticulum
E3160_25585	COG0742	ribosomal rna small subunit methyltransferase
E3160_25590	COG3776	membrane
E3160_25600	COG3714	YhhN family
E3160_25615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3160_25630	COG0628	permease
E3160_25650	COG0204	Acyl-transferase
E3160_25660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3160_25680	COG1216	Glycosyl transferase, family 2
E3160_25705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3160_25715	COG1028	Short-chain dehydrogenase reductase Sdr
E3160_25720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3160_25725	COG2091	lysine biosynthetic process via aminoadipic acid
E3160_25730	COG0747	negative chemotaxis
E3160_25735	COG0601	transmembrane transport
E3160_25740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3160_25745	COG0444	Belongs to the ABC transporter superfamily
E3160_25750	COG1124	(ABC) transporter
E3160_25760	COG2188	Transcriptional regulator
E3160_25770	COG3414	Phosphotransferase system galactitol-specific IIB component
E3160_25775	COG3775	system Galactitol-specific IIC component
E3160_25790	COG0191	fructose-bisphosphate aldolase activity
E3160_25805	COG0842	Transport permease protein
E3160_25810	COG0842	Transport permease protein
E3160_25810	COG1129	ABC transporter
E3160_25815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_25835	COG2081	HI0933 family
E3160_25840	COG0306	phosphate transporter
E3160_25850	COG0589	response to stress
E3160_25860	COG3104	oligopeptide transport
E3160_25870	COG0339	signal peptide processing
E3160_25875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E3160_25880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3160_25890	COG0640	Transcriptional regulator
E3160_25895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3160_25900	COG1393	Belongs to the ArsC family
E3160_25910	COG3065	identical protein binding
E3160_25915	COG2197	response regulator
E3160_25920	COG3720	iron ion transport
E3160_25925	COG4771	TonB-dependent receptor
E3160_25935	COG4558	Periplasmic binding protein
E3160_25945	COG3721	Heme iron utilization protein
E3160_25955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3160_25960	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E3160_25965	COG1285	pathogenesis
E3160_25980	COG3247	response to pH
E3160_25985	COG2771	luxR family
E3160_25995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3160_26000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3160_26005	COG2207	Transcriptional regulator
E3160_26010	COG2207	Transcriptional regulator
E3160_26015	COG0076	glutamate decarboxylase activity
E3160_26020	COG1858	cytochrome C peroxidase
E3160_26030	COG2197	response regulator
E3160_26035	COG0583	DNA-binding transcription factor activity
E3160_26040	COG1295	ribonuclease BN
E3160_26045	COG0477	Major facilitator Superfamily
E3160_26050	COG2982	Protein involved in outer membrane biogenesis
E3160_26055	COG2200	EAL domain
E3160_26065	COG0612	Peptidase, M16
E3160_26075	COG2199	diguanylate cyclase activity
E3160_26075	COG2200	EAL domain
E3160_26080	COG0457	Tetratricopeptide repeat
E3160_26080	COG3118	belongs to the thioredoxin family
E3160_26085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
E3160_26090	COG1215	transferase activity, transferring glycosyl groups
E3160_26120	COG2194	sulfuric ester hydrolase activity
E3160_26130	COG0814	amino acid
E3160_26135	COG4608	Belongs to the ABC transporter superfamily
E3160_26140	COG0444	Belongs to the ABC transporter superfamily
E3160_26145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3160_26150	COG0601	transmembrane transport
E3160_26160	COG0747	negative chemotaxis
E3160_26170	COG2194	sulfuric ester hydrolase activity
E3160_26175	COG3539	Fimbrial protein
E3160_26180	COG3539	Fimbrial protein
E3160_26190	COG3121	Chaperone
E3160_26195	COG3539	Fimbrial protein
E3160_26200	COG2223	nitrite transmembrane transporter activity
E3160_26205	COG5571	outer membrane autotransporter
E3160_26210	COG2818	Glycosylase
E3160_26215	COG0456	acetyltransferase
E3160_26220	COG0243	molybdopterin cofactor binding
E3160_26225	COG2885	chlorophyll binding
E3160_26240	COG2944	sequence-specific DNA binding
E3160_26245	COG1278	Cold shock
E3160_26270	COG3274	enterobacterial common antigen metabolic process
E3160_26275	COG4682	membrane
E3160_26280	COG4682	membrane
E3160_26285	COG1070	Carbohydrate kinase
E3160_26295	COG4213	ABC transporter substrate-binding protein
E3160_26305	COG4214	carbohydrate transport
E3160_26310	COG1609	Transcriptional regulator
E3160_26310	COG2207	Transcriptional regulator
E3160_26315	COG2992	FlgJ-related protein
E3160_26320	COG0366	Alpha amylase catalytic
E3160_26325	COG3977	Valine--pyruvate aminotransferase
E3160_26330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3160_26335	COG1414	Transcriptional regulator
E3160_26345	COG2211	Major facilitator Superfamily
E3160_26355	COG3713	MltA-interacting MipA family protein
E3160_26360	COG0583	DNA-binding transcription factor activity
E3160_26365	COG1566	PFAM secretion protein HlyD family protein
E3160_26380	COG1012	belongs to the aldehyde dehydrogenase family
E3160_26390	COG1454	alcohol dehydrogenase
E3160_26395	COG3276	selenocysteine insertion sequence binding
E3160_26405	COG0625	glutathione transferase activity
E3160_26410	COG3209	COG3209 Rhs family protein
E3160_26415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3160_26435	COG1566	PFAM secretion protein HlyD family protein
E3160_26445	COG2213	PTS system mannitol-specific
E3160_26445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3160_26455	COG3722	fumarate hydratase activity
E3160_26480	COG5295	Hep Hag repeat protein
E3160_26485	COG1620	l-lactate permease
E3160_26490	COG2186	Transcriptional regulator
E3160_26500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3160_26505	COG1045	serine acetyltransferase
E3160_26520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3160_26525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3160_26540	COG4942	peptidase
E3160_26545	COG2861	carbohydrate metabolic process
E3160_26550	COG1216	Glycosyl transferase, family 2
E3160_26560	COG0156	8-amino-7-oxononanoate synthase activity
E3160_26575	COG0859	PFAM glycosyl transferase family 9
E3160_26580	COG0859	PFAM glycosyl transferase family 9
E3160_26600	COG3642	lipopolysaccharide core region biosynthetic process
E3160_26610	COG0515	serine threonine protein kinase
E3160_26615	COG0438	transferase activity, transferring glycosyl groups
E3160_26620	COG0859	PFAM glycosyl transferase family 9
E3160_26625	COG1519	Transferase
E3160_26655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3160_26680	COG1561	YicC-like family, N-terminal region
E3160_26685	COG3645	SOS response
E3160_26700	COG3436	PFAM IS66 Orf2 family protein
E3160_26705	COG4372	Transposase
E3160_26710	COG2860	membrane
E3160_26720	COG0194	GDP metabolic process
E3160_26730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3160_26735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3160_26740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3160_26750	COG0786	glutamate:sodium symporter activity
E3160_26755	COG2233	PERMEase
E3160_26760	COG2982	Protein involved in outer membrane biogenesis
E3160_26765	COG1501	Belongs to the glycosyl hydrolase 31 family
E3160_26770	COG2211	Major facilitator Superfamily
E3160_26780	COG0582	viral genome integration into host DNA
E3160_26870	COG5492	domain, Protein
E3160_27040	COG0697	spore germination
E3160_27045	COG1464	Belongs to the NlpA lipoprotein family
E3160_27055	COG2814	Major facilitator Superfamily
E3160_27090	COG2271	Major facilitator Superfamily
E3160_27095	COG2271	Major facilitator Superfamily
E3160_27100	COG3851	Histidine kinase
E3160_27105	COG2197	response regulator
E3160_27125	COG0440	acetolactate synthase activity
E3160_27130	COG0028	Belongs to the TPP enzyme family
E3160_27145	COG2814	Major facilitator Superfamily
E3160_27150	COG0641	radical SAM
E3160_27160	COG2149	membrane
E3160_27170	COG3119	arylsulfatase activity
E3160_27175	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3160_27180	COG2207	Transcriptional regulator
E3160_27195	COG2188	Transcriptional regulator
E3160_27215	COG5645	(Lipo)protein
E3160_27220	COG0823	Involved in the tonB-independent uptake of proteins
E3160_27225	COG0644	oxidoreductase
E3160_27235	COG0561	phosphatase activity
E3160_27240	COG3753	Protein conserved in bacteria
E3160_27245	COG0187	DNA topoisomerase II activity
E3160_27255	COG0592	DNA-directed DNA polymerase activity
E3160_27315	COG0814	amino acid
E3160_27330	COG2091	lysine biosynthetic process via aminoadipic acid
E3160_27335	COG0431	NADPH-dependent FMN reductase
E3160_27340	COG2252	PERMEase
E3160_27345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3160_27395	COG0704	Plays a role in the regulation of phosphate uptake
E3160_27400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E3160_27405	COG0581	inorganic phosphate transmembrane transporter activity
E3160_27410	COG0573	inorganic phosphate transmembrane transporter activity
E3160_27415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3160_27435	COG3539	Fimbrial protein
E3160_27460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E3160_27510	COG3312	ion transport
E3160_27545	COG1560	Kdo2-lipid A biosynthetic process
E3160_27550	COG2194	sulfuric ester hydrolase activity
E3160_27555	COG0297	glycogen (starch) synthase activity
E3160_27560	COG0726	polysaccharide deacetylase
E3160_27605	COG4372	Transposase
E3160_27610	COG3436	PFAM IS66 Orf2 family protein
E3160_27665	COG1525	nuclease
E3160_27675	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E3160_27750	COG2963	transposase activity
E3160_27845	COG1475	DNA binding
E3160_28015	COG2274	protein secretion by the type I secretion system