locus-tag class description E7Z58_00010 ENOG4105VZ1 Replication Protein E7Z58_00025 ENOG4105ED4 portal protein E7Z58_00120 ENOG4108US3 tail fiber assembly E7Z58_00125 ENOG4105UZW Tail fiber assembly protein E7Z58_00135 ENOG4108C33 Resolvase E7Z58_00175 ENOG4105ZTC transcriptional activator, Ogr delta E7Z58_00180 ENOG4105CFP Peptidase U32 E7Z58_00185 ENOG4105KWI UPF0339 protein E7Z58_00190 ENOG4105E3W Two component transcriptional regulator (Winged helix family E7Z58_00195 ENOG4105EB3 Histidine kinase E7Z58_00205 ENOG4105BZS acriflavin resistance protein E7Z58_00230 ENOG4108M24 von Willebrand factor, type A E7Z58_00235 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase E7Z58_00240 ENOG4105ZD5 Uncharacterized protein conserved in bacteria (DUF2314) E7Z58_00245 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding E7Z58_00250 ENOG4105R8A Heat shock protein E7Z58_00255 ENOG4105D03 DNA-3-methyladenine glycosylase II E7Z58_00260 ENOG4105BZU Histidine kinase E7Z58_00265 ENOG4105DBI uridine monophosphokinase E7Z58_00275 ENOG4108GAE asmA family E7Z58_00280 ENOG4105EE5 Membrane protein terC E7Z58_00285 ENOG4105DAY polysaccharide export protein E7Z58_00290 ENOG4105KJF protein tyrosine phosphatase E7Z58_00295 ENOG4105D75 Capsular exopolysaccharide family E7Z58_00300 ENOG41090RK glycosyl transferase E7Z58_00305 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB E7Z58_00310 ENOG4107RXY Glycosyl transferase E7Z58_00315 ENOG4108NYJ Colanic acid E7Z58_00320 ENOG4105ECJ Glycosyl Transferase E7Z58_00325 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF E7Z58_00330 ENOG4105C0K Gdp-mannose 4,6-dehydratase E7Z58_00335 ENOG4105C30 Nad-dependent epimerase dehydratase E7Z58_00340 ENOG4105FGF GDP-mannose mannosyl hydrolase E7Z58_00345 ENOG4106CD9 glycosyl transferase group 1 E7Z58_00350 ENOG4105CJT Mannose-1-phosphate guanylyltransferase E7Z58_00355 ENOG4107QKV phosphomannomutase E7Z58_00360 ENOG4105D3Q Sugar transferase E7Z58_00365 ENOG4105PSV Polysaccharide Biosynthesis Protein E7Z58_00370 ENOG4105C74 pyruvyl transferase E7Z58_00375 ENOG4107T8Q Glycosyl transferase (Group 1 E7Z58_00380 ENOG4105G1A colanic acid biosynthesis protein E7Z58_00385 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E7Z58_00390 ENOG410600T transposase E7Z58_00400 ENOG4108UW5 maltose o-acetyltransferase E7Z58_00405 ENOG4105C1B dTDP-glucose 4-6-dehydratase E7Z58_00410 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) E7Z58_00415 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase E7Z58_00420 ENOG4105CMR udp-glucose 4-epimerase E7Z58_00440 ENOG4108TJN glycosyl transferase group 1 E7Z58_00450 ENOG4105CJT Mannose-1-phosphate guanylyltransferase E7Z58_00455 ENOG4107QKV phosphomannomutase E7Z58_00460 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) E7Z58_00465 ENOG4105C6Y Udp-glucose 6-dehydrogenase E7Z58_00470 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) E7Z58_00480 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase E7Z58_00495 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) E7Z58_00500 ENOG4105ECC imidazole-glycerol-phosphate dehydratase E7Z58_00525 ENOG4105VTW prevent-host-death family E7Z58_00530 ENOG4105KRQ Addiction module toxin, Txe YoeB family E7Z58_00535 ENOG4108535 NAD dependent epimerase/dehydratase family E7Z58_00540 ENOG4105EQ1 Transcriptional regulator E7Z58_00550 ENOG4105CUB amino acid E7Z58_00555 ENOG4105CUC YeeE YedE family protein E7Z58_00565 ENOG4105CJB Exodeoxyribonuclease I E7Z58_00570 ENOG4105DZ1 carboxypeptidase E7Z58_00575 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) E7Z58_00580 ENOG4105DR8 Membrane E7Z58_00615 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E7Z58_00620 ENOG4106WJE Protein of unknown function (DUF987) E7Z58_00625 ENOG4108YGG dna repair protein E7Z58_00630 ENOG4105MFG Antirestriction protein E7Z58_00635 ENOG4106H6R UPF0380 protein E7Z58_00660 ENOG4108YIV E7Z58_00665 ENOG4108F5E vimentin E7Z58_00785 ENOG4108YZT Adenosylcobinamide kinase E7Z58_00800 ENOG4108PXI ErfK YbiS YcfS YnhG E7Z58_00810 ENOG4106P55 Transcriptional regulator E7Z58_00815 ENOG4107R11 Transcriptional regulator E7Z58_00825 ENOG4105UQX Mate efflux family protein E7Z58_00835 ENOG4105CDY transcriptional regulatory protein E7Z58_00840 ENOG4105FYV Amp nucleosidase E7Z58_00845 ENOG4105CSH Transporter E7Z58_00855 ENOG4105TNG K13735 adhesin invasin E7Z58_00875 ENOG4108VKM cytochrome b561 E7Z58_00880 ENOG4108MEK Metal-binding protein YodA E7Z58_00895 ENOG4105VT2 5-hydroxyisourate hydrolase E7Z58_00900 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E7Z58_00905 ENOG4107ZY3 Histidine kinase E7Z58_00935 ENOG4105Y0K Inner membrane protein YedR E7Z58_00940 ENOG4105EST Metal Dependent Phosphohydrolase E7Z58_00945 ENOG4105DVF Cytosine-specific methyltransferase E7Z58_00950 ENOG41090BB DNA mismatch endonuclease (vsr) E7Z58_00955 ENOG4105FDR Membrane E7Z58_00960 ENOG4105CKW Inner membrane protein yedI E7Z58_00965 ENOG4105VNZ cytoplasmic protein E7Z58_00980 ENOG4105YX3 cellular response to acidity E7Z58_00990 ENOG4107TKS colanic acid capsular biosynthesis activation protein A E7Z58_00995 ENOG4105D19 Role in flagellar biosynthesis (By similarity) E7Z58_01000 ENOG4105VS8 Flagellar biosynthetic protein fliq E7Z58_01005 ENOG4105CN7 Flagellar biosynthetic protein FliP E7Z58_01010 ENOG4105K0P flagellar biosynthesis protein E7Z58_01015 ENOG4105DD5 Flagellar motor switch protein E7Z58_01020 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E7Z58_01025 ENOG4107ZI8 flagellar basal body-associated protein flil E7Z58_01030 ENOG4105WF4 Flagellar hook-length control protein E7Z58_01035 ENOG4105GSA Flagellar export protein flij E7Z58_01040 ENOG4108JIR Flagellum-specific ATP synthase E7Z58_01045 ENOG41090PJ Flagellar assembly protein E7Z58_01050 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E7Z58_01055 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) E7Z58_01070 ENOG4108RAV Conserved protein E7Z58_01075 ENOG4105KSU Redox protein E7Z58_01080 ENOG41066VF YeeE YedE family protein E7Z58_01085 ENOG4108W9D (LipO)protein E7Z58_01090 ENOG4105E5K Alpha-amylase E7Z58_01095 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) E7Z58_01100 ENOG4105MQ3 flagellar protein FliS E7Z58_01105 ENOG4105DTS flagellar hook-associated E7Z58_01110 ENOG4105I03 Flagellin E7Z58_01115 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E7Z58_01120 ENOG4108M9K flagella biosynthesis protein FliZ E7Z58_01125 ENOG4105EAB amino acid AbC transporter E7Z58_01135 ENOG4105E5Q amino acid AbC transporter E7Z58_01140 ENOG4105CDA abc transporter atp-binding protein E7Z58_01145 ENOG4105VJY transcriptional regulator E7Z58_01150 ENOG4105XVG cytoplasmic protein E7Z58_01160 ENOG4105WH1 Two component transcriptional regulator luxr family E7Z58_01170 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase E7Z58_01190 ENOG4106RHG Yeca family E7Z58_01195 ENOG4105E0U tyrosine-specific transport protein E7Z58_01200 ENOG4105VVZ metal-binding protein E7Z58_01205 ENOG41090A1 ferritin E7Z58_01210 ENOG4105P23 (LipO)protein E7Z58_01220 ENOG4105N4N Protein of unknown function (DUF2766) E7Z58_01225 ENOG4108UEC Ferritin-like protein E7Z58_01230 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator E7Z58_01235 ENOG4105C2J ABC transporter E7Z58_01240 ENOG4105CNN ABC, transporter E7Z58_01245 ENOG4108K4C ec 3.1.3.12 E7Z58_01255 ENOG4108VA4 Universal stress protein E7Z58_01265 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region E7Z58_01270 ENOG4107RD7 Flagellar Motor Protein, MotA E7Z58_01275 ENOG4105ER2 Ompa motb domain protein E7Z58_01280 ENOG4105CBS Chea signal transduction histidine kinase E7Z58_01285 ENOG4108V3W Chemotaxis protein, CheW E7Z58_01290 ENOG4105C8Q Methyl-accepting chemotaxis E7Z58_01295 ENOG4105C8Q Methyl-accepting chemotaxis E7Z58_01300 ENOG4105BZU Histidine kinase E7Z58_01305 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) E7Z58_01310 ENOG4108VYJ response regulator receiver protein E7Z58_01315 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) E7Z58_01320 ENOG4105D00 flagellar biosynthetic protein flhB E7Z58_01325 ENOG4105D7B Flagellar biosynthesis protein flha E7Z58_01330 ENOG4105W13 flagellar protein E7Z58_01340 ENOG4105C75 arginyL-tRNA synthetase E7Z58_01345 ENOG4106ZCM YecM protein E7Z58_01370 ENOG4107QY8 reductase E7Z58_01385 ENOG4105WJG Glutathione E7Z58_01390 ENOG41081XQ Conserved Protein E7Z58_01395 ENOG4105D3W isochorismatase E7Z58_01405 ENOG4108TIT dATP pyrophosphohydrolase E7Z58_01410 ENOG4105CDY transcriptional regulatory protein E7Z58_01420 ENOG4107S01 Repressor protein MetJ E7Z58_01440 ENOG4105FAV ABC, transporter E7Z58_01445 ENOG4105FDK ABC transporter E7Z58_01450 ENOG4105NXV High-affinity zinc uptake system protein E7Z58_01455 ENOG4105DR5 peptidase E7Z58_01460 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase E7Z58_01465 ENOG4105CA9 Pyruvate kinase E7Z58_01470 ENOG4106KNT transcriptional regulator E7Z58_01475 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase E7Z58_01480 ENOG4105C01 Dihydroxy-acid dehydratase E7Z58_01485 ENOG4108UHU Aldolase E7Z58_01495 ENOG4105X2V dna damage-inducible protein E7Z58_01500 ENOG4105RSZ secreted protein E7Z58_01505 ENOG4108Q2J Inner membrane protein YebE E7Z58_01510 ENOG4105CUG Oligopeptidase b E7Z58_01515 ENOG4105UMD exodeoxyribonuclease X E7Z58_01520 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E7Z58_01525 ENOG4105MPK DNA polymerase III subunit theta E7Z58_01530 ENOG4105FXM Copper resistance protein E7Z58_01535 ENOG4108PNC copper resistance E7Z58_01540 ENOG4105NKT exported protein E7Z58_01545 ENOG4108R1E Serine threonine protein phosphatase 1 E7Z58_01550 ENOG4105UVW uncharacterized protein yebW E7Z58_01555 ENOG4105WT8 Protein of unknown function (DUF1480) E7Z58_01565 ENOG4105DY2 Paraquat-inducible protein b E7Z58_01570 ENOG4105H2K paraquat-inducible protein a E7Z58_01575 ENOG4108ZGC gaf domain protein E7Z58_01585 ENOG4105CN1 protease E7Z58_01595 ENOG4105C0R drug resistance transporter emrb qaca subfamily E7Z58_01600 ENOG4105J4Q Transcriptional regulator E7Z58_01605 ENOG4105TIK E7Z58_01615 ENOG4105Q3Y exported protein E7Z58_01620 ENOG410610J Protein of unknown function (DUF2627) E7Z58_01625 ENOG4105VEQ Cold shock protein E7Z58_01630 ENOG4105DHI Methyltransferase E7Z58_01645 ENOG4105F3R pts system mannose fructose sorbose family iid E7Z58_01650 ENOG4105ETZ PTS System E7Z58_01655 ENOG4108EQA pts system E7Z58_01660 ENOG4105EE5 Membrane protein terC E7Z58_01665 ENOG4107XTP (EAL) domain protein E7Z58_01670 ENOG4105EJQ L-serine dehydratase E7Z58_01680 ENOG4105CRQ synthase (Component I) E7Z58_01690 ENOG4105V2F Uncharacterized protein yoac E7Z58_01700 ENOG4105M4H endoribonuclease L-psp E7Z58_01705 ENOG4105DVT helicase E7Z58_01710 ENOG41072GX Peptidase M22 Glycoprotease E7Z58_01715 ENOG4105Y4Z Outer Membrane Lipoprotein E7Z58_01720 ENOG4105CEY Amp-dependent synthetase and ligase E7Z58_01725 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) E7Z58_01730 ENOG4105E3J oxidoreductase E7Z58_01735 ENOG4105DVW rieske (2Fe-2S) E7Z58_01740 ENOG4105C94 Transporter E7Z58_01745 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) E7Z58_01750 ENOG4105EJC lysr family transcriptional regulator E7Z58_01760 ENOG4108YS1 cytoplasmic protein E7Z58_01765 ENOG4105YP6 Domain of unknown function (DUF1869) E7Z58_01770 ENOG4105Y3U Transglycosylase-associated protein E7Z58_01780 ENOG4106G4W E7Z58_01785 ENOG410620I Diguanylate cyclase E7Z58_01790 ENOG4105UCG Domain of unknown function (DUF333) E7Z58_01795 ENOG4105K78 MarR family Transcriptional regulator E7Z58_01800 ENOG4105DJ2 Major Facilitator Superfamily E7Z58_01805 ENOG4105R1U AraC Family Transcriptional Regulator E7Z58_01820 ENOG4108KXH Ybak prolyl-tRNA synthetase associated E7Z58_01825 ENOG4108KHP Diguanylate cyclase E7Z58_01830 ENOG4106KTS Inner membrane protein yeaI E7Z58_01840 ENOG4105CYN Serine protein kinase E7Z58_01845 ENOG4105GNX MltA-interacting MipA family protein E7Z58_01850 ENOG4105CV8 reductase E7Z58_01855 ENOG4105DSB aldose 1-epimerase E7Z58_01860 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E7Z58_01870 ENOG4105VUT cytoplasmic protein E7Z58_01875 ENOG4105CPQ Dehydrogenase E7Z58_01880 ENOG4107TE1 transport protein E7Z58_01885 ENOG4105CPQ Dehydrogenase E7Z58_01890 ENOG4105D2N Aldolase E7Z58_01895 ENOG4107UH8 sugar kinase E7Z58_01900 ENOG4105CPC Aldo Keto reductase E7Z58_01905 ENOG4105E98 transcriptional regulator DeoR family E7Z58_01910 ENOG4108KUU Inner membrane metabolite transport protein ydjE E7Z58_01915 ENOG4108RWI nicotinamidase E7Z58_01920 ENOG4105HDK L-asparaginase E7Z58_01925 ENOG4105D07 Signal peptide peptidase, SppA E7Z58_01930 ENOG41069NU Nitroreductase E7Z58_01940 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E7Z58_01945 ENOG41065FB inner membrane protein ynji E7Z58_01950 ENOG4105D82 Glutamate dehydrogenase E7Z58_01955 ENOG4105MTM Protein of unknown function (DUF1496) E7Z58_01960 ENOG4105M6F mutator MutT protein E7Z58_01965 ENOG4108T9J Cdp-alcohol phosphatidyltransferase E7Z58_01970 ENOG4107RM6 sulfurtransferase E7Z58_01975 ENOG4108VGW abc transporter atp-binding protein E7Z58_01980 ENOG4105CXZ ABC transporter, permease E7Z58_01985 ENOG4105VNH ABC transporter solute-binding protein E7Z58_01990 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E7Z58_01995 ENOG4108N5C SNARE associated Golgi protein-related protein E7Z58_02000 ENOG4108KCW iron-sulfur cluster binding E7Z58_02005 ENOG4108RSN SNARE associated Golgi E7Z58_02010 ENOG4105CGK Exodeoxyribonuclease III E7Z58_02020 ENOG4105F4X arginine E7Z58_02040 ENOG4108SPG Periplasmic Protein E7Z58_02050 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) E7Z58_02060 ENOG4105KKI DNA-binding transcriptional activator OsmE E7Z58_02070 ENOG4105VZJ PTS System E7Z58_02075 ENOG4105CK1 PTS System E7Z58_02080 ENOG4105VCP PTS System E7Z58_02090 ENOG4105F8D glycoside hydrolase family 4 E7Z58_02100 ENOG4105CH6 catalase E7Z58_02115 ENOG4108ETY sodium dicarboxylate symporter E7Z58_02120 ENOG4107K5X Membrane-bound metal-dependent hydrolase E7Z58_02125 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 E7Z58_02130 ENOG4107PN8 YfeABCD locus regulator E7Z58_02135 ENOG4105FGM Fructosamine kinase E7Z58_02140 ENOG4105P10 Uncharacterized protein ydiZ E7Z58_02145 ENOG4105DE4 1-phosphofructokinase E7Z58_02150 ENOG4108NE3 Salt-induced outer membrane protein E7Z58_02175 ENOG41082NX 50s ribosomal protein l35 E7Z58_02180 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) E7Z58_02195 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) E7Z58_02210 ENOG4108V06 Glutathione peroxidase E7Z58_02220 ENOG4108QBX (LipO)protein E7Z58_02225 ENOG4108TC0 Diguanylate phosphodiesterase E7Z58_02235 ENOG4106EDX Hemin uptake protein E7Z58_02240 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E7Z58_02250 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) E7Z58_02265 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) E7Z58_02280 ENOG4105EMV Major Facilitator E7Z58_02285 ENOG4105EMV Major Facilitator E7Z58_02290 ENOG4105SUA Ydil protein E7Z58_02300 ENOG4105IPI Membrane E7Z58_02305 ENOG4105CQB FAD linked oxidase domain protein E7Z58_02310 ENOG4105KA0 thioesterase Superfamily protein E7Z58_02315 ENOG410671Z uncharacterized protein ydiH E7Z58_02320 ENOG4108Z4V iron-sulfur cluster assembly E7Z58_02325 ENOG4105DIW FeS assembly protein SUFB E7Z58_02330 ENOG4105C3K feS assembly ATPase SufC E7Z58_02335 ENOG4105JRK feS assembly protein SufD E7Z58_02350 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E7Z58_02355 ENOG4105KMX major outer membrane lipoprotein E7Z58_02360 ENOG4105CA9 Pyruvate kinase E7Z58_02365 ENOG4105RFR Protein of unknown function (DUF2767) E7Z58_02380 ENOG4105JVW E7Z58_02385 ENOG4108393 oxidoreductase Fe-S subunit E7Z58_02390 ENOG4108NWD Cytochrome E7Z58_02395 ENOG4108Y7C Conserved Protein E7Z58_02400 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain E7Z58_02405 ENOG4105N0V mono-oxygenase ydhR E7Z58_02430 ENOG4108R6K riboflavin synthase, subunit alpha E7Z58_02435 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase E7Z58_02440 ENOG4105CZQ inner membrane transport protein YdhC E7Z58_02445 ENOG4105F52 Transcriptional regulator E7Z58_02460 ENOG4105F27 Major Facilitator E7Z58_02465 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E7Z58_02470 ENOG4105K4H Nlp p60 protein E7Z58_02475 ENOG4105M2J Glutaredoxin E7Z58_02480 ENOG4107QRT dEAD DEAH box helicase E7Z58_02485 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) E7Z58_02490 ENOG4108UYE Lactoylglutathione lyase E7Z58_02495 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E7Z58_02500 ENOG4108WUH Transcriptional regulator, TetR family E7Z58_02505 ENOG4105XZD Fe-S protein E7Z58_02510 ENOG4107RGM aldo keto reductase E7Z58_02515 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E7Z58_02520 ENOG4105DSW Fusaric acid resistance protein E7Z58_02525 ENOG4105Y49 secretion protein, HlyD family E7Z58_02540 ENOG4108XTF Outer Membrane Lipoprotein E7Z58_02550 ENOG410642K Lysozyme inhibitor E7Z58_02565 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) E7Z58_02570 ENOG4108K3A Glutathione S-transferase E7Z58_02575 ENOG4105DUX Transporter E7Z58_02580 ENOG4105CSM endonuclease III E7Z58_02590 ENOG4108UQQ Electron transport complex E7Z58_02615 ENOG4105M9B inner membrane protein ydgK E7Z58_02620 ENOG4105QZ5 OriC-binding nucleoid-associated protein E7Z58_02625 ENOG4106C6R beta-lactam resistance protein E7Z58_02630 ENOG4105D9R oxidoreductase E7Z58_02640 ENOG4105C87 Aminotransferase class I and II E7Z58_02645 ENOG4105CI1 PTS System E7Z58_02650 ENOG4107P2S Transcriptional regulator E7Z58_02655 ENOG4107ZQV short-chain dehydrogenase reductase E7Z58_02660 ENOG4105XEA Tetr family transcriptional regulator E7Z58_02670 ENOG4105CT4 transporter E7Z58_02675 ENOG4108QNI outer membrane porin protein E7Z58_02680 ENOG4106J39 exported protein E7Z58_02685 ENOG4105EIP mannose-6-phosphate isomerase E7Z58_02690 ENOG4107GFK fumarate E7Z58_02695 ENOG4105C9Q fumarate hydratase class II E7Z58_02705 ENOG4105JJR Histidine kinase E7Z58_02710 ENOG4107EXC regulatoR E7Z58_02715 ENOG4105RA2 Membrane E7Z58_02720 ENOG410642E Short chain dehydrogenase E7Z58_02725 ENOG4105D5Q Arginine ornithine antiporter E7Z58_02730 ENOG4105C5D exported protein E7Z58_02735 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E7Z58_02740 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E7Z58_02745 ENOG4105DSF transport protein E7Z58_02765 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap E7Z58_02780 ENOG4105D94 Major Facilitator Superfamily E7Z58_02785 ENOG4106NZI LysR family Transcriptional regulator E7Z58_02790 ENOG4105DAG ROK family E7Z58_02795 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E7Z58_02805 ENOG4108NEM leader-binding protein dmsD E7Z58_02810 ENOG4107KGK dmso reductase anchor subunit E7Z58_02815 ENOG4105QAX Iron-sulfur E7Z58_02820 ENOG4105C3J Cysteine desulfurase E7Z58_02825 ENOG4107QY8 reductase E7Z58_02830 ENOG4105KBG Protein of unknown function (DUF1161) E7Z58_02840 ENOG4108MK9 spermidine N(1)-acetyltransferase E7Z58_02855 ENOG4105CXK mandelate racemase muconate lactonizing E7Z58_02860 ENOG4105CPQ Dehydrogenase E7Z58_02870 ENOG4107R08 Integrase E7Z58_02885 ENOG4106G8A Qin prophage E7Z58_02920 ENOG4105WI6 cell killing protein encoded within cryptic prophage E7Z58_02935 ENOG4108MXB Protein of unknown function (DUF968) E7Z58_02940 ENOG4105HRS Antitermination protein E7Z58_02950 ENOG4107SEY Conserved Protein E7Z58_02955 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions E7Z58_02960 ENOG4105QFS Lysis protein S homolog from lambdoid prophage E7Z58_02980 ENOG4108YV9 Protein of unknown function (DUF2514) E7Z58_02985 ENOG4105VEQ Cold shock protein E7Z58_03000 ENOG4106IAW E7Z58_03005 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation E7Z58_03040 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) E7Z58_03130 ENOG4105UZW Tail fiber assembly protein E7Z58_03135 ENOG4105MN3 Resolvase E7Z58_03140 ENOG4105W3V DNA-binding, transcriptional regulator E7Z58_03155 ENOG4105DEI Mannitol dehydrogenase E7Z58_03160 ENOG41061EV selenium-binding protein YdfZ E7Z58_03165 ENOG4107XBN GntR Family Transcriptional Regulator E7Z58_03170 ENOG4105EMU Dehydrogenase E7Z58_03175 ENOG4105DGW oligopeptidase A E7Z58_03180 ENOG4108WTK competence damage-inducible protein E7Z58_03185 ENOG4108YDI single-species biofilm formation on inanimate substrate E7Z58_03190 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria E7Z58_03200 ENOG4105E5W Transporter E7Z58_03205 ENOG4108594 Permease of the drug metabolite transporter E7Z58_03210 ENOG4106DNR multiple antibiotic resistance protein E7Z58_03215 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF E7Z58_03220 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes E7Z58_03250 ENOG4105EGI Transcriptional regulator E7Z58_03255 ENOG4105C26 Dehydrogenase E7Z58_03260 ENOG4105CSV Glutaminase E7Z58_03265 ENOG4105M0C cytoplasmic protein E7Z58_03270 ENOG4105BZU Histidine kinase E7Z58_03275 ENOG4107QZW Altronate oxidoreductase E7Z58_03280 ENOG4105FFC UPF0187 protein E7Z58_03290 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound E7Z58_03300 ENOG4105D4B ABC, transporter E7Z58_03305 ENOG4105F5R ABC transporter E7Z58_03310 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane E7Z58_03315 ENOG4105C2J ABC transporter E7Z58_03320 ENOG4105DKT Transcriptional regulator E7Z58_03335 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein E7Z58_03340 ENOG4105CAF HipA N-terminal domain protein E7Z58_03355 ENOG4108WDE Fimbrial protein E7Z58_03360 ENOG4106318 fimbrial-like protein YdeR E7Z58_03365 ENOG4106PIH fimbrial-like protein ydeQ E7Z58_03370 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit E7Z58_03380 ENOG4105Z68 AraC Family Transcriptional Regulator E7Z58_03385 ENOG4105ENH Sulfatase E7Z58_03390 ENOG4105C4X radical SAM domain protein E7Z58_03405 ENOG4105PE1 Receptor E7Z58_03410 ENOG4107RAN Peptidase, M16 E7Z58_03415 ENOG4105CVK Glutamate decarboxylase E7Z58_03420 ENOG4105E5D amino acid E7Z58_03425 ENOG4105F32 YngK protein E7Z58_03430 ENOG4105BZU Histidine kinase E7Z58_03435 ENOG4105BZU Histidine kinase E7Z58_03440 ENOG4108UQS dipeptidase E7Z58_03445 ENOG4105DEF Extracellular solute-binding protein, family 5 E7Z58_03450 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E7Z58_03455 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E7Z58_03460 ENOG4105C3U ABC transporter E7Z58_03465 ENOG4107H6U ABC transporter E7Z58_03470 ENOG4108Z9K Osmotically inducible protein E7Z58_03475 ENOG4105TPS biofilm-dependent modulation protein E7Z58_03480 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein E7Z58_03490 ENOG4105DQ4 alcohol dehydrogenase E7Z58_03495 ENOG41084S7 Plasmid maintenance system antidote protein E7Z58_03500 ENOG4108MG3 formate dehydrogenase E7Z58_03505 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E7Z58_03515 ENOG4105RPH Inner membrane protein YddG E7Z58_03525 ENOG4108UI3 Leucine Rich repeat E7Z58_03535 ENOG4107QND Nitrite extrusion protein E7Z58_03540 ENOG4105CRU nitrate reductase, alpha subunit E7Z58_03545 ENOG4108IUE nitrate reductase beta subunit E7Z58_03550 ENOG4108NZN Respiratory nitrate reductase 2 delta chain E7Z58_03555 ENOG4105D0D Nitrate reductase 2, gamma subunit E7Z58_03560 ENOG4105JAB phenazine biosynthesis protein, phzf family E7Z58_03565 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase E7Z58_03570 ENOG4108MEJ flavin reductase domain protein E7Z58_03580 ENOG410600T transposase E7Z58_03600 ENOG4105CNA YD repeat protein E7Z58_03605 ENOG4105CS6 Rhs element vgr protein E7Z58_03615 ENOG4108N27 Glutathione S-transferase E7Z58_03620 ENOG4105C85 amino acid E7Z58_03625 ENOG4108NS2 receptor E7Z58_03630 ENOG4105CHB tonB-dependent Receptor E7Z58_03635 ENOG4108WYP Transcriptional regulator E7Z58_03640 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein E7Z58_03645 ENOG4108Z7F N-acetyltransferase E7Z58_03650 ENOG4108T9Y Inner membrane protein ydcZ E7Z58_03655 ENOG4105R71 cytoplasmic protein E7Z58_03660 ENOG410654E Membrane E7Z58_03675 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component E7Z58_03680 ENOG4105D81 ABC transporter, permease E7Z58_03685 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E7Z58_03690 ENOG4107TYH extracellular solute-binding protein family 1 E7Z58_03695 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E7Z58_03700 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin E7Z58_03710 ENOG4105RR0 Protein of unknown function (DUF2554) E7Z58_03715 ENOG4105CFP Peptidase U32 E7Z58_03720 ENOG4108JCI Transcriptional regulator E7Z58_03725 ENOG4105DKK Benzoate E7Z58_03730 ENOG4105D7V transposase E7Z58_03740 ENOG4108KKZ (LipO)protein E7Z58_03745 ENOG41088CC tellurite resistance protein tehB E7Z58_03750 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein E7Z58_03755 ENOG4107WE3 acetyltransferase YdcK E7Z58_03760 ENOG4108Z9I -acetyltransferase E7Z58_03765 ENOG4105Z2P Protein of unknown function (DUF465) E7Z58_03775 ENOG4105E32 cytoplasmic protein E7Z58_03780 ENOG4105DDW LysR family Transcriptional regulator E7Z58_03785 ENOG4105C8Q Methyl-accepting chemotaxis E7Z58_03790 ENOG4107NK6 Hok/gef family E7Z58_03795 ENOG4105UPP uncharacterized protein ydcA E7Z58_03800 ENOG4105CPW cytochrome b561 E7Z58_03805 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E7Z58_03810 ENOG4105C26 Dehydrogenase E7Z58_03815 ENOG4107DB1 DUF218 domain E7Z58_03820 ENOG4105CQ7 ATP-dependent helicase E7Z58_03830 ENOG41077RS Phosphatase E7Z58_03835 ENOG4105E8V Alpha Beta Hydrolase Fold protein E7Z58_03840 ENOG4108HPI phosphatidate Cytidylyltransferase E7Z58_03845 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase E7Z58_03855 ENOG4107S5I aldo keto reductase E7Z58_03860 ENOG4107EF2 surface-exposed virulence protein E7Z58_03870 ENOG4105F9F transposase E7Z58_03885 ENOG4108Z0R Transferase E7Z58_03890 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein E7Z58_03895 ENOG4105DZS Phenylacetate-CoA ligase E7Z58_03900 ENOG4105CHU acetyl-coa acetyltransferase E7Z58_03905 ENOG4108ZJI phenylacetic acid degradation protein E7Z58_03910 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase E7Z58_03915 ENOG4108UKI Enoyl-CoA hydratase E7Z58_03920 ENOG4105E39 Enoyl-CoA hydratase E7Z58_03925 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E7Z58_03930 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit E7Z58_03935 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit E7Z58_03940 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit E7Z58_03945 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit E7Z58_03950 ENOG4105DXM phenylacetic acid degradation protein E7Z58_03955 ENOG4105F11 amine oxidase E7Z58_03960 ENOG4105C26 Dehydrogenase E7Z58_03965 ENOG4108WFR AraC Family Transcriptional Regulator E7Z58_03970 ENOG4105WXT Conserved Protein E7Z58_03975 ENOG410689M (LipO)protein E7Z58_03980 ENOG4107H52 Dicarboxylate transport E7Z58_03985 ENOG4105C5I Dehydrogenase E7Z58_03990 ENOG41090X5 Heat shock protein hslJ E7Z58_04000 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) E7Z58_04005 ENOG4105FCK Membrane E7Z58_04010 ENOG4108RW8 Universal stress protein F E7Z58_04020 ENOG4105C1J atp-dependent rna helicase E7Z58_04030 ENOG4105BZU Histidine kinase E7Z58_04035 ENOG4108DG9 Smr protein MutS2 E7Z58_04040 ENOG4106KR7 LysR family Transcriptional regulator E7Z58_04045 ENOG4105CH2 amidohydrolase E7Z58_04050 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B E7Z58_04070 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E7Z58_04075 ENOG4105DS0 Transcriptional regulator, Crp Fnr family E7Z58_04080 ENOG4105Q9Y Universal stress protein E7Z58_04085 ENOG4105S5I Membrane E7Z58_04090 ENOG4105D64 Mechanosensitive ion channel E7Z58_04095 ENOG4107QSI ABC, transporter E7Z58_04100 ENOG4105EQ2 LysR family Transcriptional regulator E7Z58_04120 ENOG4105KXI murein peptide amidase A E7Z58_04125 ENOG4107S8C mandelate racemase muconate lactonizing E7Z58_04130 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) E7Z58_04135 ENOG4108JU8 Transcriptional regulator E7Z58_04145 ENOG4105CM6 amino acid regulated cytosolic protein E7Z58_04150 ENOG4105FKQ transcriptional regulator E7Z58_04155 ENOG4107EFV Outer membrane protein G E7Z58_04160 ENOG4108IJ9 (ABC) transporter E7Z58_04165 ENOG4107URF beta-phospho-glucomutase E7Z58_04170 ENOG4105C71 hydrolase family 65, central catalytic E7Z58_04175 ENOG4105CK5 oxidoreductase E7Z58_04180 ENOG4107TYA transient receptor potential locus E7Z58_04185 ENOG4107RRD Dehydrogenase E7Z58_04190 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component E7Z58_04195 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component E7Z58_04200 ENOG4105WEM extracellular solute-binding protein E7Z58_04205 ENOG4107QW3 Sucrose phosphorylase E7Z58_04210 ENOG4105K8Z Phage shock protein E7Z58_04215 ENOG4105NNG Peripheral inner membrane phage-shock protein E7Z58_04220 ENOG4105FM1 phage shock protein C E7Z58_04225 ENOG4105YYT phage shock protein B E7Z58_04230 ENOG41087YS Phage shock protein A E7Z58_04235 ENOG4105E51 psp operon transcriptional activator E7Z58_04240 ENOG4108JPW Aminotransferase E7Z58_04245 ENOG4105CJP fad dependent oxidoreductase E7Z58_04250 ENOG4105C26 Dehydrogenase E7Z58_04255 ENOG4107VRI Transcriptional regulator E7Z58_04260 ENOG4108Z86 Glutamine amidotransferase E7Z58_04265 ENOG4105CFQ glutamine synthetase E7Z58_04275 ENOG4105CUB amino acid E7Z58_04280 ENOG4105N0E Protein of unknown function (DUF2543) E7Z58_04285 ENOG4108HIY periplasmic E7Z58_04290 ENOG4108I5W peptide transport system, permease protein E7Z58_04295 ENOG4108EU3 peptide transport system, permease E7Z58_04300 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein E7Z58_04305 ENOG4108JQ2 peptide transport system atp-binding protein E7Z58_04310 ENOG4105WDY DNA (cytosine-5-)-methyltransferase E7Z58_04315 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH E7Z58_04320 ENOG4105Q4T oxidoreductase E7Z58_04335 ENOG4105BZU Histidine kinase E7Z58_04345 ENOG4105N2W Transcriptional regulator E7Z58_04350 ENOG41061RM osmotically inducible lipoprotein E7Z58_04355 ENOG4108ZJT translation initiation factor, Sui1 E7Z58_04365 ENOG4105CFV Tetratricopeptide repeat protein E7Z58_04370 ENOG4105Q4A inner membrane protein yciS E7Z58_04375 ENOG4105EYK Phosphatidylglycerophosphatase B E7Z58_04385 ENOG4107QM5 aconitate hydratase E7Z58_04410 ENOG4107R11 Transcriptional regulator E7Z58_04415 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E7Z58_04420 ENOG4105RKX Protein of unknown function (DUF2498) E7Z58_04425 ENOG4105ERU peptidase E7Z58_04430 ENOG4105UBK short-chain dehydrogenase reductase E7Z58_04435 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase E7Z58_04440 ENOG4105FE9 pseudouridine synthase E7Z58_04445 ENOG4105EG3 transmembrane signal peptide protein E7Z58_04450 ENOG4107RTD sua5 ycio yrdc ywlc family protein E7Z58_04455 ENOG4105DB7 PHP domain protein E7Z58_04465 ENOG4105CRQ synthase (Component I) E7Z58_04470 ENOG4108EFP Anthranilate synthase component II E7Z58_04475 ENOG4105DK0 Indole-3-glycerol phosphate synthase E7Z58_04495 ENOG4108Z9Z response to DNA damage stimulus E7Z58_04500 ENOG4108N8X transition metal ion binding E7Z58_04505 ENOG4105EIF outer membrane protein W E7Z58_04525 ENOG4105NAU thioesterase Superfamily protein E7Z58_04530 ENOG410822N TonB family E7Z58_04535 ENOG4105K9H YciI-like protein E7Z58_04540 ENOG4107SVH Potassium channel protein E7Z58_04560 ENOG4108JQ7 (ABC) transporter E7Z58_04565 ENOG4105C3U ABC transporter E7Z58_04570 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E7Z58_04580 ENOG4108J59 Extracellular solute-binding protein, family 5 E7Z58_04585 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein E7Z58_04590 ENOG4108EKI Dehydrogenase E7Z58_04595 ENOG4107104 thymidine kinase E7Z58_04600 ENOG4108SAU DNA-binding protein H-ns E7Z58_04605 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E7Z58_04610 ENOG4105I93 response regulator E7Z58_04615 ENOG4105D78 K07001 NTE family protein E7Z58_04625 ENOG4105CIY formyltetrahydrofolate deformylase E7Z58_04660 ENOG41076YT nitrate reductase, gamma subunit E7Z58_04665 ENOG4105R3A Nitrate reductase E7Z58_04670 ENOG4108IUE nitrate reductase beta subunit E7Z58_04675 ENOG4105CRU nitrate reductase, alpha subunit E7Z58_04680 ENOG4105DQQ Major facilitator superfamily MFS_1 E7Z58_04685 ENOG4105BZU Histidine kinase E7Z58_04690 ENOG4105WH1 Two component transcriptional regulator luxr family E7Z58_04695 ENOG4105ID0 Putative invasin E7Z58_04700 ENOG41090EX DsrE family E7Z58_04705 ENOG4108NH8 Cation transport protein E7Z58_04710 ENOG4105WS7 Cation transport regulator E7Z58_04715 ENOG4105EWV Sodium calcium exchanger membrane region E7Z58_04750 ENOG41063JG Transcriptional regulator E7Z58_04755 ENOG4108YY7 Invasion gene expression up-regulator SirB E7Z58_04760 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) E7Z58_04770 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) E7Z58_04780 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) E7Z58_04785 ENOG4105C5T Phosphoribosyl pyrophosphate synthase E7Z58_04790 ENOG4105CHH sulfate transporter E7Z58_04795 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria E7Z58_04805 ENOG4105C3G gtp-binding protein E7Z58_04810 ENOG4105I1J Autotransporter E7Z58_04815 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family E7Z58_04820 ENOG4105CMT Dihydroxyacetone kinase E7Z58_04825 ENOG4108UTZ Dihydroxyacetone kinase E7Z58_04830 ENOG4105VDH Dihydroxyacetone kinase E7Z58_04845 ENOG4105Y3U Transglycosylase-associated protein E7Z58_04850 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) E7Z58_04860 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A E7Z58_04870 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E7Z58_04880 ENOG4105ED1 spovr family E7Z58_04895 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) E7Z58_04900 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E7Z58_04905 ENOG4105KT5 UmuD protein E7Z58_04920 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase E7Z58_04930 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium E7Z58_04935 ENOG4105S66 prophage protein E7Z58_04945 ENOG4107QMS site-determining protein E7Z58_04975 ENOG410658X E7Z58_05005 ENOG4108HMX isocitrate dehydrogenase (NADP) E7Z58_05015 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 E7Z58_05055 ENOG4108ES9 ParB domain protein nuclease E7Z58_05060 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) E7Z58_05095 ENOG4105HRS Antitermination protein E7Z58_05105 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) E7Z58_05110 ENOG4105RWQ Protein of unknown function (DUF1364) E7Z58_05115 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 E7Z58_05120 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi E7Z58_05230 ENOG4108I1J Integrase E7Z58_05235 ENOG4108HMX isocitrate dehydrogenase (NADP) E7Z58_05240 ENOG4108R99 pseudouridine synthase E7Z58_05260 ENOG4107QTF adenylosuccinate lyase E7Z58_05265 ENOG4105XJC Two component transcriptional regulator (Winged helix family E7Z58_05270 ENOG4105IFJ Histidine kinase E7Z58_05275 ENOG4105EZE Cupin 4 family protein E7Z58_05285 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E7Z58_05290 ENOG4105F38 ABC transporter, permease E7Z58_05295 ENOG4105D38 putrescine abc transporter E7Z58_05300 ENOG4107RUE extracellular solute-binding protein family 1 E7Z58_05315 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) E7Z58_05325 ENOG4105D60 lipoprotein releasing system transmembrane protein E7Z58_05330 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) E7Z58_05335 ENOG4105D60 lipoprotein releasing system transmembrane protein E7Z58_05340 ENOG4105IQC Inner membrane protein YcfT E7Z58_05345 ENOG4108JA2 transcriptioN-repair coupling factor E7Z58_05350 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E7Z58_05355 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction E7Z58_05360 ENOG4108IND Tetr family transcriptional regulator E7Z58_05365 ENOG4107MBR 17 kDa surface antigen E7Z58_05370 ENOG4105CEP NADH dehydrogenase E7Z58_05390 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) E7Z58_05395 ENOG41090DQ Lipoprotein E7Z58_05400 ENOG4105K59 histidine triad (HIT) protein E7Z58_05405 ENOG4105CNM Receptor E7Z58_05410 ENOG4105CI1 PTS System E7Z58_05415 ENOG4105F8V Hydrolase, tatD family E7Z58_05420 ENOG4107QRG dna polymerase iii E7Z58_05430 ENOG4105HHA aminodeoxychorismate lyase E7Z58_05435 ENOG4105YAZ 4-amino-4-deoxychorismate lyase E7Z58_05440 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E7Z58_05445 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E7Z58_05450 ENOG4105CHR reductase E7Z58_05455 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase E7Z58_05475 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein E7Z58_05480 ENOG4108UHJ MAF-like protein E7Z58_05485 ENOG4105EI2 Pseudouridine synthase E7Z58_05490 ENOG41071G1 Uncharacterized protein YceQ E7Z58_05495 ENOG4107QQB Ribonuclease E E7Z58_05500 ENOG4105DTJ flagellar hook-associated protein E7Z58_05505 ENOG4105E1Q flagellar hook-associated protein E7Z58_05510 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj E7Z58_05525 ENOG4105CGA flagellar basal-body rod protein FlgG E7Z58_05530 ENOG4108KPB Flagellar basal-body rod protein FlgF E7Z58_05535 ENOG4105BZE flagellar hook protein, FlgE E7Z58_05540 ENOG4105W00 Flagellar hook capping protein E7Z58_05545 ENOG4108ZC9 flagellar basal-body rod protein flgc E7Z58_05550 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) E7Z58_05555 ENOG4105CKS Flagella basal body P-ring formation protein flgA E7Z58_05560 ENOG4105M9M anti-sigma28 factor FlgM E7Z58_05565 ENOG4105QVD Flagella synthesis protein FlgN E7Z58_05570 ENOG4105CJR Integral membrane protein (MviN E7Z58_05575 ENOG4105EP9 oxidoreductase E7Z58_05585 ENOG4105D9U N-acetyltransferase E7Z58_05595 ENOG4105E9S glutaredoxin 2 E7Z58_05600 ENOG4105F3T (LipO)protein E7Z58_05610 ENOG4105MEA DNA damage-inducible protein i E7Z58_05615 ENOG4105PVA Biofilm formation regulatory protein BssS E7Z58_05625 ENOG4106974 biofilm formation E7Z58_05630 ENOG4105DS1 cytochrome b561 E7Z58_05635 ENOG4108YYC ycei family E7Z58_05645 ENOG4105D1S lipid A biosynthesis E7Z58_05655 ENOG4108W47 Acidic protein msyB E7Z58_05660 ENOG4105NAC (LipO)protein E7Z58_05665 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) E7Z58_05680 ENOG4107RZC phospholipase d E7Z58_05685 ENOG4108UVJ appr-1-p processing domain protein E7Z58_05695 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) E7Z58_05700 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin E7Z58_05705 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers E7Z58_05715 ENOG41086KC Transcriptional regulator E7Z58_05720 ENOG4108XDW curli assembly protein CsgE E7Z58_05725 ENOG4108WYR Curli production assembly transport component, CsgF E7Z58_05730 ENOG4105P8Q Curli production assembly transport component CsgG E7Z58_05735 ENOG4108UQ5 membrane protein YcdZ E7Z58_05740 ENOG4107XHZ cytoplasmic chaperone TorD family protein E7Z58_05775 ENOG4108T85 Membrane E7Z58_05790 ENOG4105BZU Histidine kinase E7Z58_05810 ENOG4107BJW polysaccharide deacetylase E7Z58_05815 ENOG4105CND Glycosyl transferase, family 2 E7Z58_05820 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD E7Z58_05825 ENOG4105D5M phosphate starvation-inducible protein E7Z58_05830 ENOG4105DBE peroxidase E7Z58_05835 ENOG410650H (LipO)protein E7Z58_05840 ENOG4105EKT )-iron permease E7Z58_05845 ENOG4105CK7 Sodium proline symporter E7Z58_05855 ENOG4105C26 Dehydrogenase E7Z58_05860 ENOG4108R86 Transcriptional regulator E7Z58_05885 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) E7Z58_05900 ENOG4105C2W permease E7Z58_05905 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 E7Z58_05915 ENOG4105XH3 E7Z58_05920 ENOG4105D6F Phosphatase E7Z58_05940 ENOG4108SBI Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) E7Z58_05945 ENOG4107QY8 reductase E7Z58_05950 ENOG4105CUW cytochrome C-TYPE protein E7Z58_05955 ENOG4106WF9 DNA-binding transcriptional regulator TorR E7Z58_05960 ENOG4108SV3 Tmao reductase system periplasmic protein tort E7Z58_05965 ENOG4105BZU Histidine kinase E7Z58_05970 ENOG4105HEE Binding Domain protein E7Z58_05975 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation E7Z58_05990 ENOG4105VEQ Cold shock protein E7Z58_05995 ENOG41060EU Cold shock-like protein E7Z58_06010 ENOG4108Y9B (LipO)protein E7Z58_06015 ENOG4108W78 Pfam:DUF1017 E7Z58_06020 ENOG4105E3R (LipO)protein E7Z58_06025 ENOG4105DAY polysaccharide export protein E7Z58_06030 ENOG4107ZF2 Phosphatase E7Z58_06035 ENOG4105D75 Capsular exopolysaccharide family E7Z58_06040 ENOG4105D6F Phosphatase E7Z58_06050 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E7Z58_06055 ENOG4105C4M (Ubiquinol oxidase) subunit I E7Z58_06060 ENOG4105MVP hydrogenase-1 operon protein HyaF E7Z58_06065 ENOG4108VXY Hydrogenase-1 operon protein HyaE E7Z58_06070 ENOG4108USZ hydrogenase E7Z58_06075 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit E7Z58_06080 ENOG4105DPX Hydrogenase, large subunit E7Z58_06085 ENOG4105E3S small subunit E7Z58_06095 ENOG4108MN8 Membrane E7Z58_06100 ENOG4108Z0T Part of a sulfur-relay system (By similarity) E7Z58_06105 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 E7Z58_06120 ENOG4105K4P CoA-binding domain protein E7Z58_06135 ENOG41088T4 Helicase IV E7Z58_06140 ENOG410901E Membrane E7Z58_06145 ENOG4105EM2 membrane E7Z58_06150 ENOG4108RZ1 DNA transformation protein E7Z58_06160 ENOG4105UYK outer membrane protein a E7Z58_06170 ENOG4105DAN ATP-dependent protease E7Z58_06180 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) E7Z58_06185 ENOG4108Q2G (LipO)protein E7Z58_06190 ENOG4105DY2 Paraquat-inducible protein b E7Z58_06195 ENOG4105F1S paraquat-inducible protein a E7Z58_06200 ENOG4105C5H ABC transporter E7Z58_06205 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) E7Z58_06210 ENOG4105QVC MOSC domain-containing protein E7Z58_06215 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) E7Z58_06225 ENOG4106PH7 chaperone E7Z58_06230 ENOG4105MX3 Fimbrial E7Z58_06235 ENOG4105Q7J Fimbrial E7Z58_06240 ENOG4108MDY Fimbrial E7Z58_06245 ENOG4105CW0 outer membrane usher protein E7Z58_06265 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon E7Z58_06270 ENOG4108UZX fmn reductase E7Z58_06275 ENOG4105GVF (ABC) transporter E7Z58_06285 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component E7Z58_06290 ENOG4105E2Y ABC, transporter E7Z58_06295 ENOG4105CD8 aminopeptidase N E7Z58_06310 ENOG4105FCK Membrane E7Z58_06315 ENOG4105CGF Aromatic amino acid aminotransferase E7Z58_06320 ENOG4105C5X domain protein E7Z58_06325 ENOG4105EAQ (twin-arginine translocation) pathway signal E7Z58_06330 ENOG4105DIT ErfK YbiS YcfS YnhG family protein E7Z58_06340 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) E7Z58_06350 ENOG4106371 Methyltransferase E7Z58_06355 ENOG4107S90 membrAne E7Z58_06360 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups E7Z58_06375 ENOG4105T0Z Conserved Protein E7Z58_06380 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) E7Z58_06385 ENOG4105BZ1 (ABC) transporter E7Z58_06390 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 E7Z58_06400 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) E7Z58_06410 ENOG4108K0D peptidase, M48 E7Z58_06425 ENOG4107VMU Membrane E7Z58_06430 ENOG4105DDY UPF0142 protein ycaO E7Z58_06435 ENOG4105TMB Formate nitrite transporter E7Z58_06440 ENOG4105C6N Formate acetyltransferase E7Z58_06445 ENOG4105F1A Pyruvate formate-lyase E7Z58_06450 ENOG4108X0B nad(p)h dehydrogenase (quinone) E7Z58_06455 ENOG410642W LysR family Transcriptional regulator E7Z58_06460 ENOG4105E5D amino acid E7Z58_06470 ENOG4105CHJ isochorismatase hydrolase E7Z58_06475 ENOG4107KGK dmso reductase anchor subunit E7Z58_06480 ENOG4105QAX Iron-sulfur E7Z58_06485 ENOG4107QY8 reductase E7Z58_06495 ENOG4105D1H recombination factor protein RarA E7Z58_06505 ENOG4105CNU cell division protein FtsK E7Z58_06510 ENOG4105EW9 transcriptional regulator AsnC family E7Z58_06515 ENOG4105C3M thioredoxin reductase E7Z58_06520 ENOG4108JJ9 ABC, transporter E7Z58_06525 ENOG4108JJ8 (ABC) transporter E7Z58_06535 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) E7Z58_06555 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E7Z58_06565 ENOG4105VEQ Cold shock protein E7Z58_06570 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) E7Z58_06575 ENOG4105DJY efflux transporter, rnd family, mfp subunit E7Z58_06580 ENOG4108MJ5 VirK protein E7Z58_06585 ENOG4105CPB ATP-dependent endonuclease of the OLD family E7Z58_06590 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E7Z58_06595 ENOG4105DWU Membrane E7Z58_06605 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E7Z58_06610 ENOG4105C7K acetolactate synthase E7Z58_06615 ENOG4105C5W Aldolase E7Z58_06620 ENOG4105CGD Nad-dependent epimerase dehydratase E7Z58_06625 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase E7Z58_06630 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase E7Z58_06640 ENOG41064MM (LipO)protein E7Z58_06645 ENOG4105E5Z arginine transporter ATP-binding subunit E7Z58_06650 ENOG4106PMH Extracellular solute-binding protein family 3 E7Z58_06655 ENOG4105GBT ABC transporter E7Z58_06660 ENOG4105DMR ABC, transporter E7Z58_06665 ENOG4106TNF Periplasmic binding protein E7Z58_06675 ENOG4105RBQ inner membrane protein ybjO E7Z58_06680 ENOG4105D38 putrescine abc transporter E7Z58_06685 ENOG4105F38 ABC transporter, permease E7Z58_06690 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E7Z58_06695 ENOG4107RUE extracellular solute-binding protein family 1 E7Z58_06700 ENOG4108RMJ sensory transduction regulator E7Z58_06710 ENOG4108DBC nitroreductase E7Z58_06715 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress E7Z58_06720 ENOG41090BQ Glutaredoxin E7Z58_06725 ENOG4105GWF inner membrane protein YbjM E7Z58_06735 ENOG4108RFG Tetr family transcriptional regulator E7Z58_06740 ENOG4106UW1 Major Facilitator superfamily E7Z58_06745 ENOG4108HCJ Hydrolase E7Z58_06755 ENOG4107QF7 multi-drug E7Z58_06760 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase E7Z58_06765 ENOG4107FB0 transcriptional regulator DeoR family E7Z58_06770 ENOG4105DZ1 carboxypeptidase E7Z58_06775 ENOG4108TGY Glutathione S-transferase E7Z58_06780 ENOG4105D8V Glucose sorbosone dehydrogenase E7Z58_06785 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway E7Z58_06795 ENOG41064RH membrane protein YliF E7Z58_06800 ENOG4105BZU Histidine kinase E7Z58_06805 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E7Z58_06815 ENOG4105DEF Extracellular solute-binding protein, family 5 E7Z58_06820 ENOG4108JQ6 ABC transporter E7Z58_06825 ENOG4105D44 asparaginase E7Z58_06830 ENOG4105CVM Molybdenum cofactor synthesis domain protein E7Z58_06835 ENOG4105D06 uba thif-type nad fad binding protein E7Z58_06840 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E7Z58_06845 ENOG4105F1A Pyruvate formate-lyase E7Z58_06850 ENOG4105C6N Formate acetyltransferase E7Z58_06855 ENOG4108HCJ Hydrolase E7Z58_06860 ENOG41072TH Protein of unknown function (DUF1479) E7Z58_06865 ENOG4105C5H ABC transporter E7Z58_06870 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E7Z58_06875 ENOG4105F4P )-transporter E7Z58_06880 ENOG4105KST dependent repressor E7Z58_06890 ENOG4108I6E Sulfatase E7Z58_06895 ENOG4108T1M outer membrane protein x E7Z58_06905 ENOG4107AQZ Membrane E7Z58_06915 ENOG4107R0W ABC transporter E7Z58_06920 ENOG4105E5Q amino acid AbC transporter E7Z58_06925 ENOG4105CDA abc transporter atp-binding protein E7Z58_06930 ENOG4105D8X mechanosensitive ion channel E7Z58_06940 ENOG4105ZY9 UPF0379 protein ybiM E7Z58_06945 ENOG4108IU3 tonb-dependent siderophore receptor E7Z58_06950 ENOG4108SER Transposase E7Z58_06960 ENOG4105KSC Transcriptional regulator, TraR DksA family E7Z58_06965 ENOG4105VR4 UPF0379 protein ybiJ E7Z58_06970 ENOG4105DG4 malate L-lactate dehydrogenase E7Z58_06975 ENOG4108MTB glycosyl transferase family E7Z58_06980 ENOG4105DVT helicase E7Z58_06985 ENOG4108UV1 cellular component movement E7Z58_06990 ENOG4105C1J atp-dependent rna helicase E7Z58_06995 ENOG4107MVR Transcriptional regulator E7Z58_07005 ENOG4105CJ1 ABC, transporter E7Z58_07010 ENOG4107QWP ABC-2 type transporter E7Z58_07015 ENOG4107QWP ABC-2 type transporter E7Z58_07020 ENOG4105I9U inner membrane protein ybhQ E7Z58_07025 ENOG4105X23 Endonuclease Exonuclease phosphatase E7Z58_07030 ENOG4105DZQ phospholipase D Transphosphatidylase E7Z58_07035 ENOG4107UXM Membrane E7Z58_07040 ENOG410733J conserved inner membrane protein E7Z58_07045 ENOG4105HFZ Membrane E7Z58_07050 ENOG4108ZAF Molybdopterin E7Z58_07055 ENOG4105M00 molybdopterin converting factor, subunit 1 E7Z58_07065 ENOG4108RIR Molybdenum cofactor biosynthesis protein E7Z58_07075 ENOG4105CHW UPF0052 protein E7Z58_07085 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E7Z58_07090 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) E7Z58_07095 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E7Z58_07105 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) E7Z58_07110 ENOG4108V1U phospholipid-binding protein E7Z58_07115 ENOG4105NBR Pectinesterase E7Z58_07120 ENOG4107QM5 aconitate hydratase E7Z58_07125 ENOG4107QPK )-transporter E7Z58_07130 ENOG4105C7F AcnD-accessory protein PrpF E7Z58_07135 ENOG4105F04 LysR family Transcriptional regulator E7Z58_07145 ENOG4108K4B hydrolase E7Z58_07150 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) E7Z58_07155 ENOG4105E0C molybdate abc transporter E7Z58_07160 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein E7Z58_07165 ENOG410680R Protein of unknown function (DUF2592) E7Z58_07170 ENOG4105F4R Transcriptional regulator mode E7Z58_07175 ENOG4105DKW ABC transporter E7Z58_07180 ENOG4105CMR udp-glucose 4-epimerase E7Z58_07185 ENOG4105F0Z galactose-1-phosphate uridylyltransferase E7Z58_07195 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) E7Z58_07205 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E7Z58_07210 ENOG4105JND homeobox protein E7Z58_07215 ENOG4105PGM cation diffusion facilitator family transporter E7Z58_07220 ENOG4106Z1T Nicotinamide Mononucleotide Transporter E7Z58_07265 ENOG4105UFD tol-pal system protein YbgF E7Z58_07270 ENOG4105KCK Peptidoglycan-associated lipoprotein E7Z58_07280 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA E7Z58_07285 ENOG4105M8F Biopolymer transport protein exbD tolR E7Z58_07290 ENOG4105E02 MotA TolQ exbB proton channel E7Z58_07295 ENOG4107YD3 Thioesterase E7Z58_07300 ENOG4105KJB cyd operon protein YbgE E7Z58_07310 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E7Z58_07315 ENOG4105C4M (Ubiquinol oxidase) subunit I E7Z58_07320 ENOG4105C8I hydrolase, family 38 E7Z58_07325 ENOG4105DM4 PTS System E7Z58_07330 ENOG4105FDP GntR family transcriptional regulator E7Z58_07335 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha E7Z58_07345 ENOG4105C7S Dehydrogenase E7Z58_07350 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 E7Z58_07355 ENOG4105E33 succinate dehydrogenase E7Z58_07360 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E7Z58_07365 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein E7Z58_07370 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit E7Z58_07380 ENOG4105BZN citrate synthase E7Z58_07385 ENOG4106UBK fimbrial-like adhesin protein E7Z58_07390 ENOG4106PG1 outer membrane usher protein E7Z58_07395 ENOG4108TTM chaperone E7Z58_07400 ENOG4108MY7 Fimbrial E7Z58_07405 ENOG4108KK1 membrane protein AbrB duplication E7Z58_07415 ENOG4105E7W lamb ycsf family protein E7Z58_07420 ENOG4107R7A Allophanate hydrolase subunit 2 E7Z58_07425 ENOG4105P4J Allophanate hydrolase, subunit 1 E7Z58_07430 ENOG4107QNR UPF0135 protein E7Z58_07435 ENOG4105DUX Transporter E7Z58_07440 ENOG4105CVP deoxyribo-dipyrimidine photolyase E7Z58_07445 ENOG4107SEY Conserved Protein E7Z58_07465 ENOG4106R09 E7Z58_07480 ENOG4105CNA YD repeat protein E7Z58_07485 ENOG4105XIQ Protein of unknown function (DUF2517) E7Z58_07510 ENOG4105C08 Histidine kinase E7Z58_07515 ENOG4105EEX Two component transcriptional regulator (Winged helix family E7Z58_07525 ENOG4105CXN decarboxylase E7Z58_07530 ENOG4105D5Q Arginine ornithine antiporter E7Z58_07550 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 E7Z58_07555 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) E7Z58_07560 ENOG4105EV9 Alpha Beta Hydrolase E7Z58_07565 ENOG4105NNH LexA regulated protein E7Z58_07570 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) E7Z58_07580 ENOG41090R7 Ferric uptake E7Z58_07585 ENOG4105GX6 (LipO)protein E7Z58_07600 ENOG4105CI1 PTS System E7Z58_07610 ENOG4105CE4 GlcNAc 6-P deacetylase E7Z58_07615 ENOG4105E2R ROK family E7Z58_07620 ENOG4105D4U had-superfamily hydrolase, subfamily iia E7Z58_07625 ENOG4105CAQ asparagine synthetase E7Z58_07665 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E7Z58_07675 ENOG4105C9A Phoh family E7Z58_07685 ENOG4108JU5 Magnesium and cobalt efflux protein E7Z58_07690 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) E7Z58_07695 ENOG4107RP9 extracellular solute-binding protein, family 3 E7Z58_07700 ENOG4105EAD ABC transporter E7Z58_07705 ENOG4105DRP amino acid AbC transporter E7Z58_07710 ENOG4105CDA abc transporter atp-binding protein E7Z58_07720 ENOG4105F7F Chaperone E7Z58_07725 ENOG4105QFC Hsc56 co-chaperone of HscC E7Z58_07730 ENOG41069CF Protein of unknown function (DUF1266) E7Z58_07735 ENOG4107JFD Sel1 repeat E7Z58_07740 ENOG4105QFC Hsc56 co-chaperone of HscC E7Z58_07745 ENOG41069CF Protein of unknown function (DUF1266) E7Z58_07750 ENOG4105EUU Sel1 domain protein repeat-containing protein E7Z58_07755 ENOG4107PAI alpha helical protein E7Z58_07770 ENOG4105DJF DNA polymerase III, delta' subunit E7Z58_07780 ENOG4108TGR phosphatase E7Z58_07785 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) E7Z58_07795 ENOG4105CJN penicillin-binding protein E7Z58_07800 ENOG4105CNI cell division protein FtsW E7Z58_07805 ENOG4105K6T rare lipoprotein A E7Z58_07810 ENOG4105DZ1 carboxypeptidase E7Z58_07825 ENOG41064T2 transcriptional regulator, lysR family E7Z58_07835 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) E7Z58_07840 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E7Z58_07850 ENOG4105VEQ Cold shock protein E7Z58_07855 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) E7Z58_07860 ENOG4105CEE C4-dicarboxylate transporter E7Z58_07865 ENOG4106YYS transcriptional regulatory protein E7Z58_07870 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E7Z58_07875 ENOG4105DUA (citrate (pro-3S)-lyase ligase E7Z58_07885 ENOG4105CI0 Citrate lyase E7Z58_07890 ENOG4105CHY citrate lyase, alpha E7Z58_07905 ENOG4107QPK )-transporter E7Z58_07910 ENOG4105KTS ribonuclease E7Z58_07915 ENOG4105NXH GreA GreB family elongation factor E7Z58_07920 ENOG4105E2A Dehydrogenase E7Z58_07925 ENOG4108U51 Universal stress protein E7Z58_07930 ENOG4108JU3 Alkyl hydroperoxide reductase E7Z58_07935 ENOG4105D3R alkyl hydroperoxide reductase E7Z58_07940 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase E7Z58_07945 ENOG4105DQS Transcriptional regulator E7Z58_07950 ENOG4105BZV Phosphoadenosine phosphosulfate reductase E7Z58_07955 ENOG4105GTN ParB Domain Protein Nuclease E7Z58_07960 ENOG4105CHM Aminotransferase E7Z58_07965 ENOG4107SCQ Iron-containing alcohol dehydrogenase E7Z58_07970 ENOG4105VCD cytoplasmic protein E7Z58_07975 ENOG4105D22 carbon starvation protein E7Z58_07980 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) E7Z58_07985 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase E7Z58_07990 ENOG4105WQI isochorismatase E7Z58_07995 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase E7Z58_08000 ENOG4105E4F Isochorismate synthase E7Z58_08005 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein E7Z58_08015 ENOG4105DQ5 transport system permease protein E7Z58_08020 ENOG4105TVJ transport system, permease E7Z58_08025 ENOG4105E0A ABC, transporter E7Z58_08030 ENOG4108QY5 Ferric enterobactin transport protein E7Z58_08035 ENOG4105C0W non-ribosomal peptide synthetase E7Z58_08040 ENOG41085A6 mbth domain-containing protein E7Z58_08045 ENOG4105E93 esterase E7Z58_08050 ENOG4107RNH Outer membrane receptor FepA E7Z58_08055 ENOG4108TSE Transferase E7Z58_08060 ENOG4108SER Transposase E7Z58_08065 ENOG4107635 Hok Gef family protein E7Z58_08080 ENOG4105WQ6 Membrane E7Z58_08085 ENOG4105MSB protein, conserved in bacteria E7Z58_08090 ENOG4108RCM Nitroreductase E7Z58_08095 ENOG4105CUY Mechanosensitive ion channel E7Z58_08100 ENOG4105C85 amino acid E7Z58_08105 ENOG4108IJF Heavy metal efflux pump, CzcA E7Z58_08110 ENOG4105EP1 Efflux transporter rnd family, mfp subunit E7Z58_08115 ENOG410624V efflux system protein E7Z58_08120 ENOG4105ENJ RND efflux system, outer membrane lipoprotein E7Z58_08125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E7Z58_08130 ENOG4105GR3 Histidine kinase E7Z58_08135 ENOG4105CS6 Rhs element vgr protein E7Z58_08145 ENOG4105CNA YD repeat protein E7Z58_08150 ENOG4105CNA YD repeat protein E7Z58_08175 ENOG410600T transposase E7Z58_08180 ENOG410802X bacteriophage n4 adsorption protein b E7Z58_08185 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit E7Z58_08190 ENOG4105QUW E7Z58_08205 ENOG4108Q9V regulatoR E7Z58_08210 ENOG4108ZI2 Fimbrial protein E7Z58_08215 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) E7Z58_08220 ENOG4105CW0 outer membrane usher protein E7Z58_08225 ENOG4108AF8 Chaperone E7Z58_08230 ENOG4108WDE Fimbrial protein E7Z58_08240 ENOG4105WQ3 Rna-binding protein E7Z58_08245 ENOG4105S2T inner membrane protein YbcI E7Z58_08255 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E7Z58_08265 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) E7Z58_08270 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit E7Z58_08275 ENOG4105C5B carbamate kinase E7Z58_08280 ENOG4105G5A Protein of unknown function (DUF2877) E7Z58_08285 ENOG4107REC cytoplasmic protein E7Z58_08290 ENOG4107R1Q Membrane protein FdrA E7Z58_08295 ENOG4105DG4 malate L-lactate dehydrogenase E7Z58_08300 ENOG4105CE7 Amidase, hydantoinase carbamoylase family E7Z58_08305 ENOG4105S0E allantoin catabolism protein E7Z58_08310 ENOG4105BZW Glycerate kinase E7Z58_08315 ENOG4105DTE Xanthine uracil vitamin C permease E7Z58_08325 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease E7Z58_08330 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E7Z58_08335 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) E7Z58_08340 ENOG41060W2 glyoxylate carboligase E7Z58_08345 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region E7Z58_08350 ENOG4108Z2U ureidoglycolate hydrolase E7Z58_08355 ENOG4107653 Transcriptional regulator E7Z58_08385 ENOG4105CNA YD repeat protein E7Z58_08390 ENOG4105CV6 ABC transporter, permease E7Z58_08395 ENOG4108I0Y (ABC) transporter E7Z58_08400 ENOG4108UJV acyl-CoA thioesterase i E7Z58_08405 ENOG4105E1F short-chain dehydrogenase reductase E7Z58_08410 ENOG4107QR8 Thioredoxin E7Z58_08415 ENOG4105C4B ABC transporter, permease E7Z58_08420 ENOG41083J0 (ABC) transporter E7Z58_08425 ENOG4107QX8 SPFH domain, Band 7 family protein E7Z58_08430 ENOG4105G5H Membrane E7Z58_08435 ENOG4108Z6Z Transcriptional regulator E7Z58_08440 ENOG4107RY6 amino acid E7Z58_08445 ENOG4105CSV Glutaminase E7Z58_08450 ENOG4105C59 p-type ATPase E7Z58_08455 ENOG41081XE plasmid maintenance system antidote protein, xre family E7Z58_08465 ENOG4105MBR gumn family E7Z58_08470 ENOG4108Z66 YbaK ebsC protein E7Z58_08475 ENOG4105CGH 5'-nucleotidase E7Z58_08480 ENOG4105EU0 Major facilitator Superfamily E7Z58_08485 ENOG4105CKD glutathione-regulated potassium-efflux system protein E7Z58_08490 ENOG4107RE1 Inosine-guanosine kinase E7Z58_08515 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) E7Z58_08530 ENOG4107QMP dna polymerase iii subunits gamma and tau E7Z58_08540 ENOG4105WD1 Membrane E7Z58_08545 ENOG4108URS primosomal replication protein n'' E7Z58_08550 ENOG4106428 Protein of unknown function (DUF2496) E7Z58_08555 ENOG4105EGS Mechanosensitive ion channel E7Z58_08560 ENOG4108IG5 Transcriptional regulator E7Z58_08565 ENOG4105C1P efflux transporter, rnd family, mfp subunit E7Z58_08570 ENOG4105BZS acriflavin resistance protein E7Z58_08575 ENOG4108UKR Biofilm formation regulator YbaJ E7Z58_08580 ENOG4105KF5 hemolysin expression-modulating protein E7Z58_08585 ENOG4108UW5 maltose o-acetyltransferase E7Z58_08590 ENOG4105GSJ Inner membrane protein ylaC E7Z58_08595 ENOG41066DG (EAL) domain protein E7Z58_08600 ENOG4105KCV RNA signal recognition particle 4.5S RNA E7Z58_08610 ENOG41080UX Methyltransferase E7Z58_08615 ENOG4108MNP Glycoprotein polysaccharide metabolism E7Z58_08620 ENOG4105C29 acyl-CoA thioesterase E7Z58_08625 ENOG4105BZU Histidine kinase E7Z58_08630 ENOG4108YZA Nitrogen regulatory protein pii E7Z58_08635 ENOG4105BZ1 (ABC) transporter E7Z58_08640 ENOG4105BZ1 (ABC) transporter E7Z58_08645 ENOG4108XM1 transcriptional regulator AsnC family E7Z58_08655 ENOG4108NFA extracellular solute-binding protein E7Z58_08665 ENOG4108TGP Thioesterase superfamily protein E7Z58_08670 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein E7Z58_08675 ENOG4105EIN peptidylprolyl cis-trans isomerase E7Z58_08680 ENOG4105K70 DNA-binding protein E7Z58_08685 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) E7Z58_08705 ENOG4105M85 Bola protein E7Z58_08710 ENOG4105IEY (LipO)protein E7Z58_08715 ENOG4105EYM Major Facilitator superfamily E7Z58_08720 ENOG4105E2S oxidase) subunit II E7Z58_08725 ENOG4105BZ9 Cytochrome C oxidase, subunit I E7Z58_08730 ENOG4105CCU oxidase (Subunit III) E7Z58_08735 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) E7Z58_08745 ENOG4107RDB Major Facilitator E7Z58_08755 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) E7Z58_08760 ENOG4107S0N DJ-1 family E7Z58_08775 ENOG4105CTB Polyprenyl synthetase E7Z58_08785 ENOG4105CPC Aldo Keto reductase E7Z58_08790 ENOG4108ZAI phosphatidylglycerophosphatase a E7Z58_08795 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) E7Z58_08805 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) E7Z58_08810 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) E7Z58_08820 ENOG4108KIC (LipO)protein E7Z58_08825 ENOG4105DRB nucleoside-specific channel-forming protein E7Z58_08830 ENOG4105N1F Hnh endonuclease E7Z58_08835 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E7Z58_08840 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E7Z58_08845 ENOG4105VIE preprotein translocase, subunit YajC E7Z58_08865 ENOG4107R28 alpha amylase, catalytic region E7Z58_08870 ENOG4105C85 amino acid E7Z58_08875 ENOG4105CWM branched-chain amino acid transport system II carrier protein E7Z58_08880 ENOG4105BZU Histidine kinase E7Z58_08885 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E7Z58_08890 ENOG4107RH8 nuclease SbcCD subunit D E7Z58_08895 ENOG4105EYH Exonuclease E7Z58_08900 ENOG4105F27 Major Facilitator E7Z58_08905 ENOG4105DKQ ROK family E7Z58_08930 ENOG4105HBA AroM protein E7Z58_08935 ENOG4105SS3 E7Z58_08945 ENOG4108UPT UPF0178 protein E7Z58_08950 ENOG4105II7 pyrroline-5-carboxylate reductase E7Z58_08955 ENOG4105BZU Histidine kinase E7Z58_08960 ENOG4105VIF phosphate starvation-inducible protein E7Z58_08965 ENOG4105G6Z alkaline phosphatase E7Z58_08975 ENOG4105CPF Cell wall formation (By similarity) E7Z58_08980 ENOG4105UNH Membrane E7Z58_08985 ENOG4105FR5 inner membrane protein YaiY E7Z58_08990 ENOG4107QS8 (LipO)protein E7Z58_08995 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 E7Z58_09000 ENOG4107R6D beta-lactam binding protein AmpH E7Z58_09025 ENOG4105D52 delta-aminolevulinic acid dehydratase E7Z58_09030 ENOG4105E2B Taurine dioxygenase E7Z58_09035 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component E7Z58_09040 ENOG4108ETV ABC transporter E7Z58_09045 ENOG4106FTQ Taurine ABC transporter, periplasmic E7Z58_09050 ENOG4107W19 lmbE family E7Z58_09055 ENOG4108PBI Polysaccharide metabolism E7Z58_09065 ENOG4105SRB Uncharacterized protein yaiO E7Z58_09080 ENOG4105C4W S-formylglutathione hydrolase E7Z58_09085 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme E7Z58_09090 ENOG4108SC4 )-transporter E7Z58_09105 ENOG4105IKQ hydratase E7Z58_09115 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) E7Z58_09125 ENOG4108K2P TRANSCRIPTIONal E7Z58_09130 ENOG4105ETE Transcriptional regulator (LacI family E7Z58_09135 ENOG4105CNT hydrolase family 2 E7Z58_09140 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) E7Z58_09145 ENOG4108UW5 maltose o-acetyltransferase E7Z58_09150 ENOG4105DJ2 Major Facilitator Superfamily E7Z58_09155 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) E7Z58_09160 ENOG4107B2H carbonic anhydrase E7Z58_09165 ENOG4105DND Transcriptional regulator E7Z58_09170 ENOG4105DZC cytosine deaminase E7Z58_09175 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin E7Z58_09180 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E7Z58_09185 ENOG4105DXD 2-methylcitrate dehydratase E7Z58_09190 ENOG4105BZN citrate synthase E7Z58_09195 ENOG4105CR4 methylisocitrate lyase E7Z58_09200 ENOG4108JU7 Transcriptional regulator E7Z58_09205 ENOG4105TDT uncharacterized protein yahO E7Z58_09210 ENOG4105E82 cytochrome subunit of dehydrogenase E7Z58_09225 ENOG4105DQ4 alcohol dehydrogenase E7Z58_09230 ENOG4105DZC cytosine deaminase E7Z58_09235 ENOG4105C5B carbamate kinase E7Z58_09245 ENOG4107REC cytoplasmic protein E7Z58_09250 ENOG4107REC cytoplasmic protein E7Z58_09255 ENOG4107R1Q Membrane protein FdrA E7Z58_09265 ENOG4107SNB ankyrin repeat protein YahD E7Z58_09270 ENOG4105SZ2 membrAne E7Z58_09275 ENOG4108NUU Transcriptional regulator E7Z58_09280 ENOG4105BZU Histidine kinase E7Z58_09290 ENOG4105C94 Transporter E7Z58_09295 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) E7Z58_09300 ENOG4105C26 Dehydrogenase E7Z58_09305 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) E7Z58_09315 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) E7Z58_09320 ENOG4107QR9 Iron-sulfur cluster binding protein E7Z58_09325 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E7Z58_09330 ENOG4108K01 transcriptional regulator E7Z58_09335 ENOG4107QN2 dihydrolipoyl dehydrogenase E7Z58_09340 ENOG41066GK UPF0379 protein ykgI E7Z58_09345 ENOG4108KBJ Inner membrane protein YkgB E7Z58_09370 ENOG4105NRA 50s ribosomal protein l31 type b E7Z58_09385 ENOG4106JB4 Represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility. Acts by binding to the regulatory region of the flhDC operon E7Z58_09390 ENOG4108GWT fimbrillin MatB E7Z58_09400 ENOG4108N3D putative enzyme E7Z58_09405 ENOG4106PYX Receptor E7Z58_09410 ENOG4108UD7 cell wall organization E7Z58_09415 ENOG4105PI0 Ferredoxin E7Z58_09425 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit E7Z58_09430 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding E7Z58_09435 ENOG4105C7W Xanthine dehydrogenase E7Z58_09440 ENOG4107XAN XdhC and CoxI family E7Z58_09470 ENOG4108C33 Resolvase E7Z58_09480 ENOG4108US3 tail fiber assembly E7Z58_09485 ENOG4105UZW Tail fiber assembly protein E7Z58_09490 ENOG4105Y9F tail fiber protein E7Z58_09495 ENOG4105Y0G tail protein E7Z58_09500 ENOG4108T86 baseplate J family protein E7Z58_09520 ENOG4108NKR DNA circulation protein E7Z58_09550 ENOG4105TKZ Tail Sheath E7Z58_09595 ENOG4105EFC phage portal protein HK97 family E7Z58_09605 ENOG4105CAR Terminase, large subunit E7Z58_09625 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 E7Z58_09645 ENOG4105HRS Antitermination protein E7Z58_09650 ENOG4108MXB Protein of unknown function (DUF968) E7Z58_09660 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) E7Z58_09665 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) E7Z58_09680 ENOG4105YQ0 E7Z58_09690 ENOG4108S1U E7Z58_09725 ENOG4105H40 E7Z58_09730 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) E7Z58_09735 ENOG4108R7K Metal Dependent Phosphohydrolase E7Z58_09740 ENOG41077V0 CPS-53 (KpLE1) prophage E7Z58_09775 ENOG4105FCK Membrane E7Z58_09795 ENOG4105CIN aminoacyl-histidine dipeptidase E7Z58_09800 ENOG4108S2Y peptide Chain Release factor E7Z58_09810 ENOG4108HYG acetyltransferase E7Z58_09815 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome E7Z58_09820 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system E7Z58_09825 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E7Z58_09840 ENOG4108UK5 Transposase E7Z58_09845 ENOG4108YS0 lipoprotein YafL E7Z58_09860 ENOG4105F7V ErfK ybiS ycfS ynhG family protein E7Z58_09865 ENOG4105E7A Glutamine amidotransferase E7Z58_09875 ENOG4107QPN acyl-Coa dehydrogenase E7Z58_09880 ENOG4108WN0 inhibitor of vertebrate lysozyme E7Z58_09885 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E7Z58_09905 ENOG4107RZZ dna polymerase iii epsilon subunit E7Z58_09915 ENOG4105D1A Methyltransferase E7Z58_09920 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) E7Z58_09925 ENOG4105E9H Lytic Murein transglycosylase E7Z58_09930 ENOG4105F2W methyltransferase E7Z58_09940 ENOG4105HEI LysR family (Transcriptional regulator E7Z58_09945 ENOG4105CV8 reductase E7Z58_09980 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase E7Z58_09985 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) E7Z58_09990 ENOG4108UMI ABC transporter, permease E7Z58_09995 ENOG4105D01 (LipO)protein E7Z58_10000 ENOG4108R8X outer membrane lipoprotein E7Z58_10005 ENOG4108R96 Methyltransferase, YaeB family E7Z58_10015 ENOG4108UY0 (LipO)protein E7Z58_10020 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion E7Z58_10025 ENOG4108YZN class I peptide chain release factor E7Z58_10030 ENOG4108VWS Yaeq family E7Z58_10040 ENOG4105M1T rho-binding antiterminator E7Z58_10045 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) E7Z58_10050 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase E7Z58_10055 ENOG4105CXN decarboxylase E7Z58_10065 ENOG4105C0B DNA polymerase III (alpha subunit) E7Z58_10090 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) E7Z58_10095 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) E7Z58_10105 ENOG4105DZP Membrane-associated zinc metalloprotease E7Z58_10110 ENOG4105KNE Phosphatidate cytidylyltransferase E7Z58_10115 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) E7Z58_10120 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) E7Z58_10145 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) E7Z58_10160 ENOG4105DIN metallophosphoesterase E7Z58_10175 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR E7Z58_10180 ENOG4105C0H protease E7Z58_10195 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) E7Z58_10200 ENOG4105EN6 Membrane E7Z58_10225 ENOG4105S6R Iron-hydroxamate transporter permease subunit E7Z58_10230 ENOG4105J76 Periplasmic binding protein E7Z58_10235 ENOG4105E0A ABC, transporter E7Z58_10240 ENOG4105E0K tonB-dependent siderophore receptor E7Z58_10245 ENOG4105BZ4 penicillin-binding protein E7Z58_10250 ENOG4105CQ7 ATP-dependent helicase E7Z58_10255 ENOG4107XID 2'-5' rna ligase E7Z58_10265 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters E7Z58_10275 ENOG4105DJ0 Poly(A) Polymerase E7Z58_10280 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase E7Z58_10290 ENOG4108VEV chaperone E7Z58_10295 ENOG4105CW0 outer membrane usher protein E7Z58_10300 ENOG4108XEY fimbrial-like adhesin protein E7Z58_10305 ENOG4105SYG Fimbrial protein E7Z58_10310 ENOG4105SN2 fimbrial-like adhesin protein E7Z58_10315 ENOG4105P0Q fimbrial-like protein YadC E7Z58_10330 ENOG4108A32 Transposase E7Z58_10340 ENOG4107BJW polysaccharide deacetylase E7Z58_10345 ENOG4108YTN IIa component E7Z58_10350 ENOG4105E3A (ABC) transporter E7Z58_10355 ENOG4105DA5 (ABC) transporter E7Z58_10360 ENOG41077A9 carbonic anhydrase E7Z58_10365 ENOG4108UGV hypoxanthine phosphoribosyltransferase E7Z58_10370 ENOG4105DZG Dehydrogenase E7Z58_10375 ENOG4105E3B Multicopper oxidase E7Z58_10380 ENOG4108ZRK uncharacterized protein yacC E7Z58_10385 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) E7Z58_10400 ENOG4107QIJ Aconitate hydratase 2 E7Z58_10405 ENOG4108NST exported protein E7Z58_10410 ENOG4107QN2 dihydrolipoyl dehydrogenase E7Z58_10415 ENOG4107QSN dihydrolipoamide acetyltransferase E7Z58_10420 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) E7Z58_10425 ENOG41073TP transcriptional regulator E7Z58_10430 ENOG4105C85 amino acid E7Z58_10435 ENOG4106A72 regulatory protein AmpE E7Z58_10440 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase E7Z58_10445 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase E7Z58_10450 ENOG4108ZUW Major pilin subunit E7Z58_10455 ENOG4107QHF type ii secretion system protein e E7Z58_10460 ENOG4105D7Q type ii secretion system E7Z58_10470 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) E7Z58_10485 ENOG4105M6F mutator MutT protein E7Z58_10505 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) E7Z58_10510 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) E7Z58_10515 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) E7Z58_10520 ENOG4105CPF Cell wall formation (By similarity) E7Z58_10535 ENOG4105CNI cell division protein FtsW E7Z58_10540 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) E7Z58_10550 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) E7Z58_10555 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) E7Z58_10560 ENOG4105CJN penicillin-binding protein E7Z58_10565 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) E7Z58_10575 ENOG4108V6E Cell division protein mraZ E7Z58_10580 ENOG4107B7Y DNA-binding transcriptional regulator FruR E7Z58_10590 ENOG4108ZP8 Acetolactate synthase small subunit E7Z58_10595 ENOG4105C7K acetolactate synthase E7Z58_10605 ENOG41064T2 transcriptional regulator, lysR family E7Z58_10620 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) E7Z58_10635 ENOG4105S8Q sugar efflux transporter E7Z58_10645 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) E7Z58_10650 ENOG4105DP9 ABC transporter E7Z58_10655 ENOG4106SMU thiamine transporter membrane protein E7Z58_10660 ENOG4107T0D ABC, transporter E7Z58_10665 ENOG4108KF1 Membrane E7Z58_10670 ENOG41063TF transcriptional regulator (AraC E7Z58_10675 ENOG4105EF1 ribulokinase E7Z58_10680 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) E7Z58_10685 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase E7Z58_10690 ENOG4105CQ2 DNA polymerase E7Z58_10700 ENOG4105D3G Pseudouridine synthase E7Z58_10720 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) E7Z58_10725 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) E7Z58_10730 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) E7Z58_10755 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) E7Z58_10770 ENOG4105C54 Major Facilitator superfamily E7Z58_10775 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein E7Z58_10780 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E7Z58_10810 ENOG4105CEY Amp-dependent synthetase and ligase E7Z58_10815 ENOG4106YT9 Enoyl-CoA hydratase E7Z58_10825 ENOG4108XNW Transcriptional activatory protein CaiF E7Z58_10830 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain E7Z58_10835 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain E7Z58_10855 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase E7Z58_10870 ENOG4105DTN riboflavin biosynthesis protein ribF E7Z58_10875 ENOG410647N response to DNA damage stimulus E7Z58_10900 ENOG41063Z6 transcriptional regulator, lysR family E7Z58_10910 ENOG4105WI6 cell killing protein encoded within cryptic prophage E7Z58_10915 ENOG4108SER Transposase E7Z58_10935 ENOG4108QUJ UPF0174 protein YaaW E7Z58_10940 ENOG4106HK8 GPR1 FUN34 yaaH family protein E7Z58_10945 ENOG4108RIR Molybdenum cofactor biosynthesis protein E7Z58_10955 ENOG4105BZG amino acid carrier protein E7Z58_10960 ENOG4105D1Q UPF0246 protein E7Z58_10965 ENOG41062C6 Protein of unknown function (DUF2502) E7Z58_10970 ENOG4105D98 threonine synthase E7Z58_10980 ENOG4105CFH Aspartokinase E7Z58_10990 ENOG4106FVC RNA methyltransferase E7Z58_10995 ENOG410759A E7Z58_11000 ENOG41065U4 response regulator E7Z58_11005 ENOG4105CT7 inner membrane cred family protein E7Z58_11010 ENOG4105EB3 Histidine kinase E7Z58_11015 ENOG4105E3W Two component transcriptional regulator (Winged helix family E7Z58_11020 ENOG4108RH0 Crea protein E7Z58_11025 ENOG4105UEI Transcriptional Regulator AraC Family E7Z58_11035 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) E7Z58_11045 ENOG4107SC1 transglycosylase E7Z58_11050 ENOG4105C5H ABC transporter E7Z58_11055 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase E7Z58_11060 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) E7Z58_11065 ENOG4105EAC phosphoserine phosphatase E7Z58_11070 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) E7Z58_11105 ENOG4105G0K glycine radical enzyme YjjI family E7Z58_11110 ENOG41076CZ activating enzyme E7Z58_11115 ENOG4105EYA deoxyribonuclease E7Z58_11120 ENOG4108NRW Phospholipase, patatin family E7Z58_11130 ENOG4105K3G Periplasmic Protein E7Z58_11140 ENOG4105PAD Hydrolase E7Z58_11145 ENOG4105KEG ribosomal-protein-alanine acetyltransferase E7Z58_11150 ENOG4108WPU DNA polymerase III subunit psi E7Z58_11155 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) E7Z58_11175 ENOG4105YBH Protein of unknown function (DUF1435) E7Z58_11180 ENOG4108819 ferric iron reductase E7Z58_11185 ENOG4108T94 DNA-binding transcriptional activator BglJ E7Z58_11190 ENOG4108N8T regulatoR E7Z58_11195 ENOG4105DWK Membrane E7Z58_11210 ENOG4106CVF DNA replication protein E7Z58_11215 ENOG4105RI1 glycoprotein receptor E7Z58_11245 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E7Z58_11250 ENOG4105C8Q Methyl-accepting chemotaxis E7Z58_11255 ENOG4108V8F Transcriptional regulator, MarR family E7Z58_11260 ENOG4105ERH Fumarylacetoacetate hydrolase E7Z58_11265 ENOG4105C26 Dehydrogenase E7Z58_11270 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase E7Z58_11300 ENOG4105EFA 4-hydroxyphenylacetate E7Z58_11305 ENOG4107UWN reductase E7Z58_11310 ENOG4105D22 carbon starvation protein E7Z58_11315 ENOG4105VCD cytoplasmic protein E7Z58_11320 ENOG4105CKI cobalamin synthesis protein E7Z58_11360 ENOG4106DIZ Domain of unknown function (DUF1127) E7Z58_11365 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E7Z58_11380 ENOG41083G8 Multidrug resistance protein MdtM E7Z58_11385 ENOG4106BRA Membrane E7Z58_11390 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase E7Z58_11395 ENOG4105CIZ coA-substrate-specific enzyme activase E7Z58_11410 ENOG4105CBP Major Facilitator E7Z58_11420 ENOG41074DU domain protein E7Z58_11425 ENOG4108P2H Inner membrane protein YjiG E7Z58_11430 ENOG4105DYB Isoaspartyl dipeptidase E7Z58_11435 ENOG4107YNJ LysR family Transcriptional regulator E7Z58_11455 ENOG4105C6F GntR Family Transcriptional Regulator E7Z58_11460 ENOG4105DEI Mannitol dehydrogenase E7Z58_11475 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin E7Z58_11480 ENOG4108T65 Fimbrial E7Z58_11485 ENOG4108SQA Fimbrial E7Z58_11490 ENOG4105CW0 outer membrane usher protein E7Z58_11495 ENOG4108NAE Fimbrial chaperone protein E7Z58_11500 ENOG4108S54 Fimbrial protein E7Z58_11510 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off E7Z58_11520 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria E7Z58_11525 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) E7Z58_11630 ENOG4105DQ4 alcohol dehydrogenase E7Z58_11635 ENOG4105D7A ATP-binding protein E7Z58_11640 ENOG4108K5H permease YjgP YjgQ family protein E7Z58_11645 ENOG4108M8S permease YjgP YjgQ family protein E7Z58_11655 ENOG4105MYG DNA polymerase iii, chi subunit E7Z58_11660 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) E7Z58_11675 ENOG4108M3P Membrane E7Z58_11680 ENOG4108MJ3 acetyltransferase E7Z58_11685 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) E7Z58_11705 ENOG4105XEP YhcH YjgK YiaL family protein E7Z58_11710 ENOG4108XFH Transcriptional regulator E7Z58_11715 ENOG4105F6U Short-chain dehydrogenase reductase Sdr E7Z58_11720 ENOG4108UQ8 endoribonuclease L-psp E7Z58_11725 ENOG41077AM PyrBI operon attenuator E7Z58_11740 ENOG4105KME endoribonuclease L-psp E7Z58_11745 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic E7Z58_11755 ENOG4105D4X repressor E7Z58_11760 ENOG4105C5Y PTS System E7Z58_11765 ENOG4105CG3 alpha amylase, catalytic region E7Z58_11770 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase E7Z58_11775 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) E7Z58_11785 ENOG4105CMS peptidase U62, modulator of DNA gyrase E7Z58_11795 ENOG4105DFU Cell wall formation (By similarity) E7Z58_11805 ENOG41062B0 ABC transporter, permease E7Z58_11810 ENOG4107R9N ABC transporter E7Z58_11815 ENOG4105C2J ABC transporter E7Z58_11820 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator E7Z58_11825 ENOG4105F0N pyrophosphate phospho-hydrolase E7Z58_11830 ENOG4108ZHD aig2 family E7Z58_11835 ENOG4105MA0 exported protein E7Z58_11840 ENOG4105CFU surface antigen E7Z58_11850 ENOG4105C37 (CBS) domain E7Z58_11855 ENOG41061GZ Protein of unknown function (DUF1107) E7Z58_11860 ENOG4108UUE Transcriptional regulator E7Z58_11865 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase E7Z58_11875 ENOG4105KVH Transcriptional regulator E7Z58_11880 ENOG4105ECR NmrA family E7Z58_11885 ENOG4105DXC membrane E7Z58_11895 ENOG4105C85 amino acid E7Z58_11900 ENOG4108V1T peptidylprolyl cis-trans isomerase E7Z58_11910 ENOG4105FHY Opacity-associated protein A E7Z58_11920 ENOG4105CHR reductase E7Z58_11930 ENOG4105E39 Enoyl-CoA hydratase E7Z58_11935 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) E7Z58_11940 ENOG4107S3R L-aspartate oxidase E7Z58_11945 ENOG41069H7 transport system small permease component E7Z58_11950 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E7Z58_11955 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit E7Z58_11965 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) E7Z58_11980 ENOG4105KIT UPF0379 protein yjfY E7Z58_12005 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport E7Z58_12010 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC E7Z58_12025 ENOG4108MXZ Esterase E7Z58_12030 ENOG4105WSB biofilm stress and motility protein A E7Z58_12035 ENOG4105S17 UPF0379 protein yjfN E7Z58_12040 ENOG4105CSU acyl-Coa dehydrogenase E7Z58_12045 ENOG4106032 Glutathionylspermidine synthase E7Z58_12050 ENOG4108KXT Conserved Protein E7Z58_12055 ENOG4105Z6B inner membrane protein yjfl E7Z58_12060 ENOG4107VNS Protein of unknown function (DUF2491) E7Z58_12065 ENOG4108P9J Phage shock protein A E7Z58_12070 ENOG4105FUX Conserved Protein E7Z58_12075 ENOG4105C2N RNA methyltransferase TrmH family group 3 E7Z58_12080 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) E7Z58_12100 ENOG4105EPW hflc protein E7Z58_12105 ENOG4107QJR hflk protein E7Z58_12110 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) E7Z58_12115 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E7Z58_12130 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E7Z58_12135 ENOG4105K8N protein family UPF0079, ATPase E7Z58_12140 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) E7Z58_12145 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) E7Z58_12185 ENOG4105EGS Mechanosensitive ion channel E7Z58_12190 ENOG4106CG8 Inner membrane protein YjeO E7Z58_12195 ENOG4106V5W E7Z58_12200 ENOG4107SC7 Inner membrane transporter yjeM E7Z58_12210 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E7Z58_12215 ENOG4105E33 succinate dehydrogenase E7Z58_12230 ENOG41066YJ Beta-lactamase E7Z58_12235 ENOG4105QNF Outer membrane lipoprotein E7Z58_12240 ENOG4105KPY Small multidrug resistance protein E7Z58_12245 ENOG4106BSU Entericidin B E7Z58_12250 ENOG4106HKS Entericidin EcnA/B family E7Z58_12260 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein E7Z58_12265 ENOG4105MTB Uncharacterized protein YjeJ E7Z58_12270 ENOG4108ZVF (LipO)protein E7Z58_12285 ENOG4105DVH amino acid E7Z58_12290 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 E7Z58_12295 ENOG4108IJ0 Aspartate ammonia-lyase E7Z58_12300 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E7Z58_12310 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) E7Z58_12315 ENOG4108SIC Transcriptional regulator E7Z58_12330 ENOG4108M3R transcriptional activator CadC E7Z58_12340 ENOG4105D5Q Arginine ornithine antiporter E7Z58_12345 ENOG4105CXN decarboxylase E7Z58_12350 ENOG4105DUX Transporter E7Z58_12355 ENOG4105CRK lysyL-tRNA synthetase E7Z58_12370 ENOG410830R acetyltransferase E7Z58_12375 ENOG4105VR1 Pfam:DUF1271 E7Z58_12380 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E7Z58_12385 ENOG4108MRH transcriptional regulatory protein E7Z58_12390 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E7Z58_12395 ENOG4107GFK fumarate E7Z58_12400 ENOG4108R5S membrane E7Z58_12405 ENOG4105CT4 transporter E7Z58_12410 ENOG4105F8D glycoside hydrolase family 4 E7Z58_12415 ENOG4108K2B transcriptional regulator E7Z58_12420 ENOG4105CXN decarboxylase E7Z58_12425 ENOG4106ZGR Transcriptional regulator E7Z58_12430 ENOG4105D5Q Arginine ornithine antiporter E7Z58_12435 ENOG4105DIJ Phosphoethanolamine transferase E7Z58_12440 ENOG4105XJC Two component transcriptional regulator (Winged helix family E7Z58_12445 ENOG4105ECM Sensor protein basS pmrB E7Z58_12455 ENOG4105CSH Transporter E7Z58_12460 ENOG4108YIV E7Z58_12465 ENOG4108F5E vimentin E7Z58_12470 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA E7Z58_12475 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase E7Z58_12480 ENOG4105D5T phosphonate abc transporter E7Z58_12485 ENOG4105EHI Phosphonate ABC transporter, periplasmic E7Z58_12495 ENOG4107RJJ Transcriptional regulator E7Z58_12500 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG E7Z58_12505 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH E7Z58_12510 ENOG4105EKV Phosphonate metabolism protein E7Z58_12515 ENOG4105FT8 Phosphonate metabolism E7Z58_12520 ENOG4105ENV phosphonate C-P lyase system protein PhnK E7Z58_12525 ENOG4105HRV phosphonate c-p lyase system protein phnl E7Z58_12530 ENOG4105FD8 phosphonate metabolism protein PhnM E7Z58_12535 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) E7Z58_12540 ENOG410849A acetyltransferase, (GNAT) family E7Z58_12545 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein E7Z58_12550 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 E7Z58_12555 ENOG4108YZG isomerase E7Z58_12560 ENOG4105NYY transcriptional regulator, RpiR E7Z58_12565 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E7Z58_12570 ENOG4105C2J ABC transporter E7Z58_12575 ENOG4105CNN ABC, transporter E7Z58_12580 ENOG4105UP7 3-epimerase E7Z58_12585 ENOG4107TFG D-allose kinase E7Z58_12590 ENOG4105EUZ Beta-lactamase domain protein E7Z58_12595 ENOG4106833 E7Z58_12600 ENOG4105J12 Multidrug resistance protein mdtN E7Z58_12605 ENOG4108MI0 Resistance protein E7Z58_12610 ENOG4105ETP RND efflux system, outer membrane lipoprotein E7Z58_12620 ENOG41082ND Uncharacterized protein yjcO E7Z58_12625 ENOG4105CK2 sodium dicarboxylate symporter E7Z58_12630 ENOG4108W0S formate-dependent nitrite reductase complex E7Z58_12640 ENOG4108QKW cytochrome c-type biogenesis protein E7Z58_12645 ENOG4105DVI reductase, NrfD E7Z58_12650 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E7Z58_12655 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit E7Z58_12665 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E7Z58_12670 ENOG41062QD Membrane E7Z58_12690 ENOG4105EEQ Na H antiporter E7Z58_12695 ENOG4105C7N Xanthine uracil vitamin C permease E7Z58_12700 ENOG4108Z4X TRANSCRIPTIONal E7Z58_12705 ENOG4108W3Q Transcriptional regulator E7Z58_12715 ENOG4105PMV Membrane E7Z58_12720 ENOG4108UUM single-stranded DNA-binding protein E7Z58_12725 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) E7Z58_12730 ENOG4105MSB protein, conserved in bacteria E7Z58_12735 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme E7Z58_12740 ENOG4105F0S class B acid phosphatase E7Z58_12750 ENOG4105CGF Aromatic amino acid aminotransferase E7Z58_12755 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E7Z58_12760 ENOG4105CDU Replicative dna helicase E7Z58_12765 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein E7Z58_12770 ENOG4105P4Z Phage shock protein G E7Z58_12775 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E7Z58_12785 ENOG4106FE3 DNA repair E7Z58_12805 ENOG4108US3 tail fiber assembly E7Z58_12810 ENOG4105UZW Tail fiber assembly protein E7Z58_12815 ENOG4105Y9F tail fiber protein E7Z58_12820 ENOG4105Y0G tail protein E7Z58_12825 ENOG4108T86 baseplate J family protein E7Z58_12845 ENOG4108NKR DNA circulation protein E7Z58_12870 ENOG4105TKZ Tail Sheath E7Z58_12915 ENOG4105CAR Terminase, large subunit E7Z58_12940 ENOG4105NVB glycoside hydrolase, family 19 E7Z58_12960 ENOG4105HGD Antitermination protein E7Z58_12965 ENOG4108MXB Protein of unknown function (DUF968) E7Z58_12975 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) E7Z58_12980 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) E7Z58_12995 ENOG4105YQ0 E7Z58_13005 ENOG4106050 phage regulatory protein, rha family E7Z58_13010 ENOG4108S1U E7Z58_13015 ENOG41078CG DNA-binding transcriptional regulator E7Z58_13020 ENOG4105RDA repressor E7Z58_13035 ENOG4108R7K Metal Dependent Phosphohydrolase E7Z58_13040 ENOG41077V0 CPS-53 (KpLE1) prophage E7Z58_13090 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E7Z58_13100 ENOG4105MYN Zinc uptake regulation protein E7Z58_13105 ENOG4105VDW Csbd family E7Z58_13110 ENOG4107R73 Mate efflux family protein E7Z58_13120 ENOG41080IJ Diacylglycerol kinase E7Z58_13145 ENOG4107W52 maltose operon periplasmic protein E7Z58_13155 ENOG4108IJ9 (ABC) transporter E7Z58_13160 ENOG4107FKK extracellular solute-binding protein family 1 E7Z58_13165 ENOG4105D56 permease protein E7Z58_13170 ENOG4105EG2 ABC transporter, permease E7Z58_13175 ENOG4107QNK )-transporter E7Z58_13190 ENOG4105E3R (LipO)protein E7Z58_13195 ENOG4108Q9C Periplasmic Protein E7Z58_13200 ENOG4108MDC (LipO)protein E7Z58_13220 ENOG4105CFH Aspartokinase E7Z58_13225 ENOG4108ZR5 Conserved Protein E7Z58_13230 ENOG4105FE9 pseudouridine synthase E7Z58_13240 ENOG4105EAM Na Pi-cotransporter E7Z58_13245 ENOG4105C3R Methionine synthase E7Z58_13250 ENOG41069M3 Transcriptional regulator E7Z58_13265 ENOG4108I9X Isocitrate lyase E7Z58_13270 ENOG4107QP3 malate synthase g E7Z58_13275 ENOG4105CVG Homoserine O-transsuccinylase E7Z58_13280 ENOG4105K5X acetyltransferase E7Z58_13285 ENOG41062WK cellular response to acidity E7Z58_13315 ENOG4105C12 Phosphoribosylglycinamide synthetase E7Z58_13320 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E7Z58_13325 ENOG4105BZU Histidine kinase E7Z58_13330 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism E7Z58_13335 ENOG4108T8B Protein of unknown function (DUF1481) E7Z58_13340 ENOG4105K70 DNA-binding protein E7Z58_13345 ENOG4105R2J Conserved Protein E7Z58_13370 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) E7Z58_13380 ENOG4105D06 uba thif-type nad fad binding protein E7Z58_13385 ENOG4105WHD thiamine biosynthesis protein ThiS E7Z58_13395 ENOG4105D41 biosynthesis protein thiH E7Z58_13400 ENOG410645W Thiamin biosynthesis protein ThiH E7Z58_13435 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) E7Z58_13440 ENOG4105PM1 preprotein translocase subunit SecE E7Z58_13475 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase E7Z58_13480 ENOG4105D4A Cell wall formation (By similarity) E7Z58_13510 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) E7Z58_13520 ENOG4108Y73 Membrane E7Z58_13525 ENOG4105EJ2 Transcriptional regulator E7Z58_13535 ENOG4105C5Q Transcriptional regulator E7Z58_13545 ENOG4105CAS nag kinase E7Z58_13550 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase E7Z58_13565 ENOG4105DIJ Phosphoethanolamine transferase E7Z58_13570 ENOG4106R3P AraC family transcriptional regulator E7Z58_13575 ENOG4108XCZ PTS System E7Z58_13580 ENOG4108AHH pyruvate formate lyase II activase E7Z58_13585 ENOG4105C6N Formate acetyltransferase E7Z58_13590 ENOG4108YRF PTS System E7Z58_13595 ENOG4105DM4 PTS System E7Z58_13600 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E7Z58_13605 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E7Z58_13610 ENOG4105DCT glycerol dehydrogenase E7Z58_13615 ENOG4108XC3 NADH ubiquinone oxidoreductase E7Z58_13620 ENOG4108Q5Y Membrane E7Z58_13625 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) E7Z58_13630 ENOG4105SYT Methylenetetrahydrofolate reductase E7Z58_13635 ENOG4105CFH Aspartokinase E7Z58_13640 ENOG4105C28 cystathionine E7Z58_13650 ENOG4107S01 Repressor protein MetJ E7Z58_13660 ENOG4105C25 Primosomal protein n' E7Z58_13665 ENOG4105ETE Transcriptional regulator (LacI family E7Z58_13670 ENOG41063M6 Cell Division Protein E7Z58_13680 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) E7Z58_13685 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase E7Z58_13700 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E7Z58_13710 ENOG4105CBT Fructose-1,6-bisphosphatase E7Z58_13715 ENOG4105DP0 ferredoxin-NADP reductase E7Z58_13725 ENOG41065TG regulatoR E7Z58_13730 ENOG4108VTS Membrane E7Z58_13735 ENOG4105EBK exported protein E7Z58_13750 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein E7Z58_13765 ENOG4105FMW periplasmic E7Z58_13770 ENOG4105E3W Two component transcriptional regulator (Winged helix family E7Z58_13775 ENOG4105E0F Histidine kinase E7Z58_13780 ENOG4108RPX mosc domain containing protein E7Z58_13790 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E7Z58_13835 ENOG4108V87 frv operon regulatory protein E7Z58_13845 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) E7Z58_13850 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) E7Z58_13855 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E7Z58_13860 ENOG4108MG3 formate dehydrogenase E7Z58_13870 ENOG41068KX affects formate dehydrogenase-N E7Z58_13875 ENOG4106UEE Transcriptional regulator E7Z58_13880 ENOG4105SUU thioesterase domain E7Z58_13895 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 E7Z58_13910 ENOG4108K85 Transcriptional regulator E7Z58_13920 ENOG4105C5F glutamine synthetase E7Z58_13925 ENOG4105CUX Signal transduction histidine kinase E7Z58_13930 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E7Z58_13935 ENOG4106FIY E7Z58_13940 ENOG4105D4P Coproporphyrinogen iii oxidase E7Z58_13945 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) E7Z58_13955 ENOG4105C2M dna polymerase I E7Z58_13965 ENOG4106HNH Acyl-transferase E7Z58_13975 ENOG4108Z33 Thiol disulfide Interchange Protein E7Z58_13980 ENOG4105E27 serine threonine protein kinase E7Z58_13985 ENOG4105PC1 Conserved Protein E7Z58_13990 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) E7Z58_13995 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b E7Z58_14025 ENOG4108RR8 protoporphyrinogen oxidase E7Z58_14030 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) E7Z58_14035 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein E7Z58_14050 ENOG4105CHU acetyl-coa acetyltransferase E7Z58_14055 ENOG4107QK7 reductase E7Z58_14060 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) E7Z58_14065 ENOG4105MDZ Transcriptional activator rfaH E7Z58_14070 ENOG4105F8V Hydrolase, tatD family E7Z58_14075 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) E7Z58_14080 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) E7Z58_14085 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) E7Z58_14095 ENOG4105JC1 sterol-binding domain protein E7Z58_14105 ENOG4105CGY Dna recombination protein E7Z58_14110 ENOG4108I5U Uridine phosphorylase E7Z58_14115 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) E7Z58_14120 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) E7Z58_14125 ENOG4105DZ2 Transcriptional regulator E7Z58_14130 ENOG4105EMK carboxylate amino acid amine transporter E7Z58_14135 ENOG4105DQF Hydrolase E7Z58_14140 ENOG4108EUD Lysophospholipase E7Z58_14155 ENOG4105C9U ATP-dependent DNA helicase RecQ E7Z58_14160 ENOG4105HDD phospholipase E7Z58_14165 ENOG4108VUY thioesterase Superfamily protein E7Z58_14170 ENOG4105FR1 rard protein E7Z58_14185 ENOG4107QUT magnesium and cobalt transport protein CorA E7Z58_14190 ENOG4108T58 Mg2 transport protein CorA E7Z58_14195 ENOG4105C4R Atp-dependent dna helicase E7Z58_14200 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant E7Z58_14210 ENOG4105CT0 Protein of unknown function, DUF484 E7Z58_14220 ENOG4105S7Z (LipO)protein E7Z58_14235 ENOG4107T0K Adenylate cyclase E7Z58_14245 ENOG41076E6 Uroporphyrinogen-III Synthase E7Z58_14250 ENOG4105ECF c-methyltransferase E7Z58_14255 ENOG410601J HemY protein E7Z58_14260 ENOG4105ENH Sulfatase E7Z58_14265 ENOG4105C4X radical SAM domain protein E7Z58_14290 ENOG4105C85 amino acid E7Z58_14305 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) E7Z58_14310 ENOG4105EGZ biosynthesis protein E7Z58_14315 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E7Z58_14320 ENOG4108WJ1 acetyltransferase E7Z58_14325 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) E7Z58_14330 ENOG4105C1B dTDP-glucose 4-6-dehydratase E7Z58_14335 ENOG4108IJ1 Dehydrogenase E7Z58_14340 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase E7Z58_14345 ENOG4105SFE lipopolysaccharide biosynthesis protein E7Z58_14350 ENOG4105ESV Glycosyl transferase, family 4 E7Z58_14365 ENOG4105K63 Thioredoxin E7Z58_14380 ENOG4105C4R Atp-dependent dna helicase E7Z58_14390 ENOG4105KQ5 peptidylprolyl cis-trans isomerase E7Z58_14400 ENOG4105EMY transcriptional regulator E7Z58_14405 ENOG4105C7B Threonine dehydratase E7Z58_14415 ENOG4105CM2 brancheD-chain amino acid aminotransferase E7Z58_14420 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit E7Z58_14440 ENOG4105C0P Mg chelatase subunit ChlI E7Z58_14445 ENOG4108WFC UPF0438 protein yifE E7Z58_14485 ENOG4107EJG GntR family transcriptional regulator E7Z58_14495 ENOG4105ETE Transcriptional regulator (LacI family E7Z58_14500 ENOG4108RVA ribokinase E7Z58_14505 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E7Z58_14510 ENOG4105CNN ABC, transporter E7Z58_14515 ENOG4105C2J ABC transporter E7Z58_14520 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) E7Z58_14535 ENOG4105EV2 VWA domain protein interacting with AAA ATPase E7Z58_14540 ENOG4105CU9 asparagine synthetase A E7Z58_14545 ENOG4108VVK transcriptional Regulator, AsnC E7Z58_14550 ENOG4105QTB Flavodoxin E7Z58_14565 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation E7Z58_14575 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) E7Z58_14615 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) E7Z58_14700 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) E7Z58_14705 ENOG4105C8U phosphate abc transporter E7Z58_14710 ENOG4105E2Z phosphate ABC transporter (Permease E7Z58_14715 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) E7Z58_14720 ENOG4108UTW Plays a role in the regulation of phosphate uptake E7Z58_14725 ENOG4105CID antiterminator E7Z58_14730 ENOG4105C5Y PTS System E7Z58_14735 ENOG4105CS2 ec 3.2.1.21 E7Z58_14745 ENOG4105DYC esterase E7Z58_14750 ENOG4107VKM 6-phosphogluconolactonase E7Z58_14755 ENOG4106611 bacteriocin immunity E7Z58_14765 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 E7Z58_14770 ENOG4105C7N Xanthine uracil vitamin C permease E7Z58_14775 ENOG4108YYH Nadph-dependent fmn reductase E7Z58_14780 ENOG4105E8Q phosphopantetheinyl transferase E7Z58_14795 ENOG4108P6C Tryptophan transporter of low affinity E7Z58_14845 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) E7Z58_14855 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E7Z58_14865 ENOG410667J hydrolase E7Z58_14870 ENOG410657R replicase EC 2.7 E7Z58_14875 ENOG4105EMF GntR family transcriptional regulator E7Z58_14880 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 E7Z58_14885 ENOG4108RTU Aldolase E7Z58_14895 ENOG4105DJB Major Facilitator Superfamily E7Z58_14900 ENOG4107WAP fad NAD(P)-binding domain E7Z58_14905 ENOG4105D99 atp gtp-binding protein E7Z58_14910 ENOG4105R2A (LipO)protein E7Z58_14930 ENOG4105FDP GntR family transcriptional regulator E7Z58_14935 ENOG4105CI1 PTS System E7Z58_14940 ENOG4105F8D glycoside hydrolase family 4 E7Z58_14955 ENOG4105D7V transposase E7Z58_14960 ENOG4105VG5 Membrane E7Z58_14965 ENOG4105JP4 Inner membrane protein yidG E7Z58_14970 ENOG4105J13 transcriptional regulator E7Z58_14975 ENOG4105E5M Multidrug resistance protein D E7Z58_14990 ENOG4105C7K acetolactate synthase E7Z58_14995 ENOG4105M71 acetolactate synthase 1 regulatory subunit E7Z58_15000 ENOG4108KX4 response regulator E7Z58_15005 ENOG4105BZU Histidine kinase E7Z58_15010 ENOG4105CXY transporter E7Z58_15015 ENOG4105CXY transporter E7Z58_15025 ENOG4105C7N Xanthine uracil vitamin C permease E7Z58_15030 ENOG4108SAJ Protein of unknown function (DUF1198) E7Z58_15040 ENOG4105T8A Uncharacterized protein YicS E7Z58_15045 ENOG4105D01 (LipO)protein E7Z58_15050 ENOG4108UZ3 Transporter E7Z58_15055 ENOG4105S8Q sugar efflux transporter E7Z58_15085 ENOG4105CJQ hydrolase, family 31 E7Z58_15090 ENOG4105JV1 AsmA family E7Z58_15095 ENOG4105C2W permease E7Z58_15100 ENOG4105D6U Sodium Glutamate Symporter E7Z58_15105 ENOG4105CB5 ATP-dependent DNA helicase recG E7Z58_15110 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase E7Z58_15115 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E7Z58_15120 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) E7Z58_15125 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) E7Z58_15135 ENOG4105EN6 Membrane E7Z58_15140 ENOG4105F5P DNA-damage-inducible protein d E7Z58_15145 ENOG4105DSJ YicC domain protein E7Z58_15170 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase E7Z58_15185 ENOG4105W0E 50S ribosomal protein L33 E7Z58_15200 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase E7Z58_15205 ENOG4105DKP glycosyl transferase, family 9 E7Z58_15210 ENOG4107RJ7 Glycosyl transferase (Group 1 E7Z58_15215 ENOG4107543 (lipo)polysaccharide E7Z58_15220 ENOG4106AH0 Glycosyl Transferase E7Z58_15225 ENOG4105X1N Glycosyl transferase family 8 E7Z58_15235 ENOG4105X1N Glycosyl transferase family 8 E7Z58_15240 ENOG4105K64 Glycosyl transferase, family 2 E7Z58_15245 ENOG41068PG O-Antigen polymerase E7Z58_15250 ENOG4105D16 lipopolysaccharide heptosyltransferase i E7Z58_15255 ENOG4105XA0 heptosyltransferase ii E7Z58_15265 ENOG4108SEH involved in lipopolysaccharide biosynthesis E7Z58_15270 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E7Z58_15280 ENOG4105K64 Glycosyl transferase, family 2 E7Z58_15285 ENOG4105PXI polysaccharide deacetylase E7Z58_15290 ENOG41063SB peptidase E7Z58_15295 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) E7Z58_15305 ENOG4107YZP Rhodanese domain protein E7Z58_15310 ENOG4105VW4 glutaredoxin 3 E7Z58_15325 ENOG4105D7W serine acetyltransferase E7Z58_15330 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) E7Z58_15340 ENOG41073TP transcriptional regulator E7Z58_15345 ENOG4105DAA L-lactate E7Z58_15350 ENOG4108YYI Protein of unknown function (DUF2810) E7Z58_15360 ENOG4105E61 Mannitol repressor protein E7Z58_15370 ENOG4105CTS PTS system mannitol-specific E7Z58_15375 ENOG4105FP6 Protein of unknown function (DUF3302) E7Z58_15380 ENOG4105EFX secretion protein, HlyD family E7Z58_15415 ENOG4105NUP lyase containing HEAT-repeat E7Z58_15420 ENOG4105CNA YD repeat protein E7Z58_15425 ENOG4108U78 Glutathione S-transferase E7Z58_15435 ENOG4105EM7 Selenocysteine-specific translation elongation factor E7Z58_15440 ENOG4105C0A alcohol dehydrogenase E7Z58_15445 ENOG4105C26 Dehydrogenase E7Z58_15455 ENOG4105KK7 inner membrane protein YiaW E7Z58_15460 ENOG4105EFX secretion protein, HlyD family E7Z58_15465 ENOG4108Q2M Transcriptional regulator E7Z58_15470 ENOG4105GNX MltA-interacting MipA family protein E7Z58_15480 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase E7Z58_15485 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase E7Z58_15490 ENOG4105H6Q decarboxylase E7Z58_15495 ENOG4105CMG Carbohydrate kinase E7Z58_15500 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit E7Z58_15505 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E7Z58_15510 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter E7Z58_15515 ENOG4108R66 Conserved Protein E7Z58_15525 ENOG4105J4Q Transcriptional regulator E7Z58_15530 ENOG4108XIB electron transport protein ysaA E7Z58_15535 ENOG4105JKW Valine--pyruvate aminotransferase E7Z58_15540 ENOG4107T9C Alpha amylase catalytic region E7Z58_15545 ENOG4108UR8 BAX protein E7Z58_15550 ENOG4105T16 Transcriptional regulator (AraC family) E7Z58_15555 ENOG4107RNG ABC transporter E7Z58_15560 ENOG4105C2J ABC transporter E7Z58_15565 ENOG4105DFW ABC transporter E7Z58_15575 ENOG4105CMG Carbohydrate kinase E7Z58_15580 ENOG410688U Inner membrane protein yiaB E7Z58_15585 ENOG4108Z12 YiaAB two helix domain-containing protein E7Z58_15590 ENOG4105MEV Acyl-transferase E7Z58_15595 ENOG4105RGS lipoprotein ysaB E7Z58_15600 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit E7Z58_15625 ENOG41060TC Hok gef cell toxic protein E7Z58_15630 ENOG4105VEQ Cold shock protein E7Z58_15635 ENOG4105MVF Transcriptional regulator E7Z58_15640 ENOG4106JH6 (LipO)protein E7Z58_15650 ENOG4108ZG0 Ompa motb domain protein E7Z58_15655 ENOG4107QY8 reductase E7Z58_15660 ENOG4105HNP -acetyltransferase E7Z58_15665 ENOG4108R3E Dna-3-methyladenine glycosylase i E7Z58_15670 ENOG4105EAX Putative lipase E7Z58_15675 ENOG4105FCD Major Facilitator E7Z58_15680 ENOG4105DIJ Phosphoethanolamine transferase E7Z58_15690 ENOG4105DEF Extracellular solute-binding protein, family 5 E7Z58_15700 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E7Z58_15705 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E7Z58_15710 ENOG4105C3U ABC transporter E7Z58_15715 ENOG4108JQ7 (ABC) transporter E7Z58_15720 ENOG4105C44 Serine transporter E7Z58_15745 ENOG4105WQA Cellulose biosynthesis protein BcsF E7Z58_15750 ENOG4105U74 cellulose biosynthesis protein BcsE E7Z58_15755 ENOG410661M cytoplasmic protein E7Z58_15765 ENOG4107QZ7 Cellulose synthase catalytic subunit E7Z58_15770 ENOG4107EEX Cellulose synthase regulator protein E7Z58_15775 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) E7Z58_15780 ENOG4105EJG cellulose synthase E7Z58_15785 ENOG4105BZU Histidine kinase E7Z58_15795 ENOG4105CS0 peptidase E7Z58_15800 ENOG4107SS6 2-dehydro-3-deoxygluconokinase E7Z58_15805 ENOG4105CMB EAL domain-containing protein E7Z58_15810 ENOG41066T0 asmA family E7Z58_15815 ENOG4105CSH Transporter E7Z58_15820 ENOG4107H3J ribonuclease E7Z58_15825 ENOG4105CBN LysR family transcriptional regulator E7Z58_15830 ENOG4106S2D Transcriptional regulator E7Z58_15835 ENOG4105E53 ec 3.2.1.28 E7Z58_15840 ENOG4105CA0 peroxidase E7Z58_15845 ENOG4105CVK Glutamate decarboxylase E7Z58_15855 ENOG4108NKV transcriptional regulator E7Z58_15860 ENOG4105D3F AraC Family Transcriptional Regulator E7Z58_15865 ENOG4105BZS acriflavin resistance protein E7Z58_15870 ENOG4105C1P efflux transporter, rnd family, mfp subunit E7Z58_15880 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci E7Z58_15885 ENOG4108YK4 Acid-resistance membrane protein E7Z58_15890 ENOG41060V2 Acid-resistance protein E7Z58_15895 ENOG4105XXV Acid-resistance protein E7Z58_15900 ENOG4105KT7 mgtC SapB transporter E7Z58_15910 ENOG4105Y4Z Outer Membrane Lipoprotein E7Z58_15920 ENOG4105K89 arsenate reductase E7Z58_15925 ENOG4107R5R arsenical pump membrane protein E7Z58_15930 ENOG4105KBH arsR family transcriptional regulator E7Z58_15940 ENOG4105DC8 reductase E7Z58_15945 ENOG4105D6S protein involved in catabolism of external DNA E7Z58_15950 ENOG4105DGW oligopeptidase A E7Z58_15955 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) E7Z58_15960 ENOG4105DUX Transporter E7Z58_15965 ENOG4108M6U Universal stress protein A E7Z58_15975 ENOG4105CJ3 phosphate transporter E7Z58_15980 ENOG4105CBX hi0933 family E7Z58_16045 ENOG410624V efflux system protein E7Z58_16075 ENOG4105DR5 peptidase E7Z58_16085 ENOG4105E3B Multicopper oxidase E7Z58_16090 ENOG4105VR0 copper resistance E7Z58_16095 ENOG4105JDN Copper resistance protein E7Z58_16100 ENOG4108PG2 copper resistance E7Z58_16105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E7Z58_16110 ENOG4105GR3 Histidine kinase E7Z58_16120 ENOG4107UNS conserved inner membrane protein E7Z58_16135 ENOG4105D0S secretion protein (HlyD E7Z58_16140 ENOG4105CJ1 ABC, transporter E7Z58_16145 ENOG4105CMI transporter E7Z58_16165 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E7Z58_16170 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E7Z58_16175 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E7Z58_16180 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E7Z58_16185 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein E7Z58_16190 ENOG4107YAK holo-(acyl carrier protein) synthase 2 E7Z58_16195 ENOG4105DSF transport protein E7Z58_16200 ENOG4105F9N Major Facilitator Superfamily E7Z58_16205 ENOG4108W1V Lipoprotein E7Z58_16210 ENOG4105EX9 Membrane E7Z58_16220 ENOG4105C59 p-type ATPase E7Z58_16225 ENOG4107FS9 Membrane E7Z58_16235 ENOG4105MG3 Membrane E7Z58_16240 ENOG4106H78 methyltransferase E7Z58_16245 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) E7Z58_16250 ENOG4105CAK Cell division ATP-binding protein ftsE E7Z58_16255 ENOG4105CRP Part of the ABC transporter FtsEX involved in E7Z58_16260 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E7Z58_16265 ENOG4105CP9 extracellular ligand-binding receptor E7Z58_16270 ENOG4105U59 -acetyltransferase E7Z58_16275 ENOG4105CP9 extracellular ligand-binding receptor E7Z58_16280 ENOG4105C32 Amino acid ABC transporter (Permease) E7Z58_16285 ENOG4105CF8 branched-chain amino acid ABC transporter, permease E7Z58_16290 ENOG4105C0Z ABC transporter E7Z58_16295 ENOG4108IV0 ABC, transporter E7Z58_16300 ENOG4105BZ7 extracellular solute-binding protein family 1 E7Z58_16305 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component E7Z58_16310 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component E7Z58_16315 ENOG4108IJ9 (ABC) transporter E7Z58_16320 ENOG4107T6V glycerophosphoryl diester phosphodiesterase E7Z58_16325 ENOG4105WC8 Conserved Protein E7Z58_16330 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) E7Z58_16335 ENOG4106FA4 E7Z58_16355 ENOG4105GMB type VI secretion system effector, hcp1 family E7Z58_16360 ENOG4105WCN acetyltransferase E7Z58_16365 ENOG4105D9R oxidoreductase E7Z58_16370 ENOG4105C2I pirin domain protein E7Z58_16375 ENOG4105DIQ Transcriptional regulator E7Z58_16380 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family E7Z58_16385 ENOG4105C6Z Gluconate E7Z58_16390 ENOG41076UM multiple antibiotic resistance (MarC)-related protein E7Z58_16395 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E7Z58_16420 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E7Z58_16430 ENOG4105C6V Glycerol-3-phosphate dehydrogenase E7Z58_16445 ENOG4105E98 transcriptional regulator DeoR family E7Z58_16450 ENOG4105CYB regulatoR E7Z58_16455 ENOG4105E0Y RtcB Protein E7Z58_16470 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E7Z58_16475 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) E7Z58_16480 ENOG4105C6Z Gluconate E7Z58_16490 ENOG4105MJ2 Competence protein E7Z58_16500 ENOG4105DNE Transposase E7Z58_16510 ENOG4105CE1 Ferrous iron transport protein b E7Z58_16515 ENOG4105XFK Ferrous iron transport protein A E7Z58_16520 ENOG4105BZM domain protein E7Z58_16525 ENOG4108RRZ Transcription elongation factor GreB E7Z58_16530 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E7Z58_16535 ENOG4105E0F Histidine kinase E7Z58_16545 ENOG4108MAJ Membrane E7Z58_16555 ENOG4105VEJ Heat shock protein E7Z58_16560 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 E7Z58_16565 ENOG4105DQY intracellular growth attenuator E7Z58_16570 ENOG4107RK2 ADP-ribose diphosphatase NudE E7Z58_16575 ENOG4108JQC penicillin-binding protein 1A E7Z58_16580 ENOG4108U1Q Pilus assembly protein E7Z58_16585 ENOG41065NF Fimbrial assembly family protein E7Z58_16590 ENOG4105XPX DNA utilization protein HofO E7Z58_16595 ENOG4105ITY Required for the use of extracellular DNA as a nutrient E7Z58_16600 ENOG4105E4G Type IV pilus E7Z58_16615 ENOG4105EGB membrane protein DamX E7Z58_16620 ENOG4105DFE Dna adenine methylase E7Z58_16625 ENOG4105DJV ribulose-phosphate 3-epimerase E7Z58_16630 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E7Z58_16635 ENOG4105C31 Tryptophanyl-tRNA synthetase E7Z58_16645 ENOG4108M21 E7Z58_16650 ENOG4105RMW regulation of transcription, DNA-dependent E7Z58_16655 ENOG4108626 Racemase E7Z58_16660 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) E7Z58_16665 ENOG41080QX K07048 phosphotriesterase-related protein E7Z58_16670 ENOG4105MUZ Protein of unknown function DUF2620 E7Z58_16675 ENOG4106M0N transport system permease protein E7Z58_16680 ENOG4106PKC pyridoxal phosphate binding E7Z58_16685 ENOG4105FDP GntR family transcriptional regulator E7Z58_16690 ENOG4108KPW sugar kinase E7Z58_16695 ENOG4107Y0V Not clear, may be involved in an isomerization step E7Z58_16700 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine E7Z58_16705 ENOG4107QHQ amino acid E7Z58_16710 ENOG4105VYH E7Z58_16720 ENOG4107V9H nitrite transporter E7Z58_16725 ENOG4105WZK nitrite reductase NADPH small subunit E7Z58_16730 ENOG4107QZF nitrite reductase NADPH large subunit E7Z58_16740 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E7Z58_16745 ENOG4106195 uncharacterized protein yhfG E7Z58_16750 ENOG4105MZU cell filamentation protein E7Z58_16755 ENOG4105DDQ anthranilate synthase E7Z58_16760 ENOG4105C8Y Acetylornithine aminotransferase E7Z58_16765 ENOG410613R integral membrane protein, YccS YhfK family E7Z58_16770 ENOG4107RYR Transcriptional regulator, Crp Fnr family E7Z58_16775 ENOG4108UKZ OsmC family E7Z58_16780 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) E7Z58_16790 ENOG4105DNZ Alpha Beta Hydrolase E7Z58_16795 ENOG4105C5H ABC transporter E7Z58_16810 ENOG4105VKU nucleicacid-binding protein E7Z58_16815 ENOG4108YZY peptidylprolyl cis-trans isomerase E7Z58_16825 ENOG4108V1T peptidylprolyl cis-trans isomerase E7Z58_16830 ENOG4105WWK YheO domain protein E7Z58_16870 ENOG4108NNZ chitinase E7Z58_16875 ENOG4105W53 bacterioferritin-associated ferredoxin E7Z58_16880 ENOG4108UQY Iron-storage protein E7Z58_16885 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) E7Z58_16895 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) E7Z58_16900 ENOG4105R04 type II secretion system protein K E7Z58_16915 ENOG41069X0 general secretion pathway protein h E7Z58_16920 ENOG4108VAU general secretion pathway protein G E7Z58_16925 ENOG4105D7Q type ii secretion system E7Z58_16930 ENOG4107QHF type ii secretion system protein e E7Z58_16935 ENOG4105GVR general secretion pathway protein D E7Z58_16940 ENOG4107KSE General secretion pathway protein C E7Z58_16945 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression E7Z58_16950 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication E7Z58_16965 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) E7Z58_16970 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) E7Z58_16980 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) E7Z58_16985 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) E7Z58_16990 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) E7Z58_16995 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) E7Z58_17005 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal E7Z58_17015 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) E7Z58_17030 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) E7Z58_17040 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) E7Z58_17045 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) E7Z58_17060 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) E7Z58_17065 ENOG41067V7 50S ribosomal protein L36 E7Z58_17070 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits E7Z58_17080 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) E7Z58_17085 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) E7Z58_17095 ENOG4105VTS DnaJ-like, subfamily C E7Z58_17100 ENOG4105W1Y Transcriptional regulator E7Z58_17105 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system E7Z58_17115 ENOG4105C1A potassium transporter peripheral membrane E7Z58_17135 ENOG4105C79 DNA protecting protein DprA E7Z58_17145 ENOG4108WI1 Dna topoisomerase E7Z58_17150 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) E7Z58_17160 ENOG4105SG3 Protein of unknown function (DUF1488) E7Z58_17165 ENOG4108Z0R Transferase E7Z58_17205 ENOG4105CDA abc transporter atp-binding protein E7Z58_17210 ENOG4105DRP amino acid AbC transporter E7Z58_17215 ENOG4105EZ7 amino acid ABC transporter E7Z58_17225 ENOG4105XCM membrane LIPOPROTEIN E7Z58_17230 ENOG4105BZS acriflavin resistance protein E7Z58_17235 ENOG4105C1P efflux transporter, rnd family, mfp subunit E7Z58_17240 ENOG4108XG4 DNA-binding transcriptional regulator E7Z58_17245 ENOG41061ME transport protein E7Z58_17250 ENOG4105CEC DNA methylase N-4 N-6 E7Z58_17255 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) E7Z58_17260 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E7Z58_17270 ENOG4108IA2 Sodium pantothenate symporter E7Z58_17275 ENOG4105RG0 Membrane E7Z58_17280 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase E7Z58_17285 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein E7Z58_17290 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family E7Z58_17295 ENOG41062P1 Diguanylate cyclase phosphodiesterase E7Z58_17305 ENOG4105DFF Rod shape-determining protein mreb E7Z58_17310 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) E7Z58_17315 ENOG4105VQ7 Rod shape-determining protein MreD E7Z58_17320 ENOG4108Z03 MAF-like protein E7Z58_17325 ENOG4105C03 ribonuclease E7Z58_17330 ENOG4105QD6 exported protein E7Z58_17335 ENOG4105D1U peptidase U62 modulator of DNA gyrase E7Z58_17340 ENOG4105CR8 Transcriptional regulator E7Z58_17360 ENOG4105UNR (Barnase) inhibitor E7Z58_17365 ENOG4105RID UPF0379 protein yhcN E7Z58_17380 ENOG4105C0H protease E7Z58_17385 ENOG4105C0H protease E7Z58_17390 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III E7Z58_17395 ENOG4105D6Z AFG1 family ATPase E7Z58_17405 ENOG4108UJD 30S ribosomal protein S9 E7Z58_17410 ENOG4107MKT Stringent starvation protein a E7Z58_17415 ENOG4105KB2 stringent starvation protein b E7Z58_17420 ENOG4105CEE C4-dicarboxylate transporter E7Z58_17450 ENOG4108R66 Conserved Protein E7Z58_17455 ENOG4105DFS Conserved Protein E7Z58_17465 ENOG4105BZ8 glutamate synthase E7Z58_17470 ENOG4105CBC glutamate synthase E7Z58_17475 ENOG4105N5T Radical SAM Protein E7Z58_17480 ENOG4105BZU Histidine kinase E7Z58_17485 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain E7Z58_17495 ENOG4108NIH transferase activity, transferring phosphorus-containing groups E7Z58_17500 ENOG41080Z8 PHOSPHOCARRIER protein E7Z58_17510 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN E7Z58_17515 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA E7Z58_17520 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E7Z58_17525 ENOG4108IUZ ABC transporter E7Z58_17530 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA E7Z58_17535 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) E7Z58_17540 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase E7Z58_17545 ENOG4105C2X Arabinose 5-phosphate isomerase E7Z58_17550 ENOG4105FEU K -dependent Na -Ca exchanger E7Z58_17555 ENOG4105DHJ ABC, transporter E7Z58_17560 ENOG4105CY3 ABC transporter, permease E7Z58_17565 ENOG4107PE3 Mammalian cell entry related domain protein E7Z58_17570 ENOG4105E3I toluene tolerance E7Z58_17575 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane E7Z58_17580 ENOG4105VFK BolA family E7Z58_17590 ENOG4105HVQ Regulatory factor of maltose metabolism E7Z58_17595 ENOG4105EAH synthase E7Z58_17610 ENOG4105QYV Membrane E7Z58_17620 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase E7Z58_17625 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) E7Z58_17630 ENOG4105HBR Rna-binding protein E7Z58_17635 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) E7Z58_17640 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) E7Z58_17645 ENOG4105EEI dihydropteroate synthase E7Z58_17670 ENOG4105DIJ Phosphoethanolamine transferase E7Z58_17690 ENOG4105CHV Transcription elongation factor NusA E7Z58_17705 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) E7Z58_17720 ENOG4105RT1 May be involved in cell division (By similarity) E7Z58_17730 ENOG4105C1J atp-dependent rna helicase E7Z58_17735 ENOG4105CIC tryptophan-specific transport protein E7Z58_17740 ENOG4105DEN Luciferase family E7Z58_17745 ENOG4106RZ4 Peptidase U32 E7Z58_17750 ENOG4105CFP Peptidase U32 E7Z58_17755 ENOG4105XPQ lipid carrier protein E7Z58_17760 ENOG4108YYD acetyltransferase E7Z58_17775 ENOG4107R7Y intracellular protease Pfpi family E7Z58_17780 ENOG4105K4T epimerase E7Z58_17785 ENOG4107S21 permease E7Z58_17790 ENOG4105W4M Transport-associated protein E7Z58_17795 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) E7Z58_17805 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) E7Z58_17810 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) E7Z58_17815 ENOG4105I74 Fimbrial protein E7Z58_17820 ENOG4105CW0 outer membrane usher protein E7Z58_17825 ENOG4108VCD Chaperone E7Z58_17830 ENOG4105Q10 Fimbrial-like protein E7Z58_17835 ENOG4106HBN Galactosamine-6-phosphate isomerase E7Z58_17840 ENOG4105F3R pts system mannose fructose sorbose family iid E7Z58_17845 ENOG4105ETZ PTS System E7Z58_17850 ENOG4108UZY PTS System E7Z58_17860 ENOG4105E70 isomerase E7Z58_17865 ENOG4105CE4 GlcNAc 6-P deacetylase E7Z58_17870 ENOG4108YTN IIa component E7Z58_17875 ENOG4105F3R pts system mannose fructose sorbose family iid E7Z58_17885 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB E7Z58_17895 ENOG4105E98 transcriptional regulator DeoR family E7Z58_17900 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression E7Z58_17905 ENOG4105ZEG Suppressor protein E7Z58_17910 ENOG4105CTX dehydratase E7Z58_17915 ENOG4105DJB Major Facilitator Superfamily E7Z58_17925 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E7Z58_17930 ENOG4105BZW Glycerate kinase E7Z58_17970 ENOG4105C7B Threonine dehydratase E7Z58_17980 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E7Z58_17985 ENOG4105C6N Formate acetyltransferase E7Z58_17990 ENOG4105KME endoribonuclease L-psp E7Z58_17995 ENOG4105EJQ L-serine dehydratase E7Z58_18000 ENOG4105C44 Serine transporter E7Z58_18010 ENOG4106D80 Uncharacterized protein YhaL E7Z58_18015 ENOG4108CNN domain protein E7Z58_18020 ENOG4105CWB LysR family transcriptional Regulator E7Z58_18025 ENOG4105KAF membrAne E7Z58_18030 ENOG4105KAF membrAne E7Z58_18035 ENOG4105CHF Glutathione S-transferase E7Z58_18040 ENOG4108VBZ doxx family E7Z58_18045 ENOG4105YJD E7Z58_18050 ENOG41090KG Inner membrane protein YqjE E7Z58_18055 ENOG4105NE1 Conserved Protein E7Z58_18060 ENOG4105WAY exported protein E7Z58_18065 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) E7Z58_18070 ENOG4106W5V Membrane E7Z58_18075 ENOG4107YCY Transcriptional regulator E7Z58_18080 ENOG4105DPW Major facilitator superfamily MFS_1 E7Z58_18090 ENOG4105CTX dehydratase E7Z58_18095 ENOG4105P66 Membrane E7Z58_18100 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) E7Z58_18105 ENOG4105DU1 integral membrane protein, terc E7Z58_18110 ENOG4105EE0 oxidoreductase E7Z58_18115 ENOG4108UB4 uncharacterized protein ygjQ E7Z58_18120 ENOG4108VKG metal-dependent hydrolase E7Z58_18125 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) E7Z58_18130 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase E7Z58_18135 ENOG4108Z3N Transcriptional regulator E7Z58_18140 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E7Z58_18145 ENOG4107WCA isomerase E7Z58_18150 ENOG4107W6W Conserved Protein E7Z58_18155 ENOG4105E5D amino acid E7Z58_18160 ENOG4105FK9 beta-D-galactosidase beta subunit E7Z58_18165 ENOG4105CNT hydrolase family 2 E7Z58_18170 ENOG4105CQ4 Transcriptional regulator E7Z58_18175 ENOG4108Y51 tRNA-binding protein E7Z58_18185 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor E7Z58_18190 ENOG4105NTW Transcriptional regulator E7Z58_18195 ENOG4105Q26 Siderophore-interacting protein E7Z58_18210 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E7Z58_18215 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) E7Z58_18220 ENOG4105VCC 30S ribosomal protein S21 E7Z58_18230 ENOG4107QPK )-transporter E7Z58_18235 ENOG4107GFK fumarate E7Z58_18240 ENOG4106DSS Tartrate dehydratase subunit alpha E7Z58_18245 ENOG4105EJC lysr family transcriptional regulator E7Z58_18255 ENOG4107ZVW dihydroneopterin aldolase E7Z58_18260 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) E7Z58_18270 ENOG4106MWK domain protein E7Z58_18275 ENOG4105I7R Adenylate cyclase E7Z58_18300 ENOG4107S78 Band 7 protein E7Z58_18305 ENOG4105PV3 Inner membrane protein yqiJ E7Z58_18315 ENOG4108MY7 Fimbrial E7Z58_18330 ENOG4105H8W Fimbrial protein E7Z58_18335 ENOG4105W0Z cytoplasmic protein E7Z58_18350 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b E7Z58_18355 ENOG4106032 Glutathionylspermidine synthase E7Z58_18365 ENOG4105DFG type I secretion outer membrane protein E7Z58_18370 ENOG41087AY ADP-Ribose pyrophosphatase E7Z58_18375 ENOG4108SX3 cytoplasmic protein E7Z58_18380 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) E7Z58_18385 ENOG4105IPS esterase E7Z58_18390 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E7Z58_18395 ENOG4105VRH Antibiotic biosynthesis monooxygenase E7Z58_18400 ENOG4105NF4 modulator of drug activity E7Z58_18405 ENOG4107DEU Inner membrane protein YgiZ E7Z58_18410 ENOG4105DHQ Histidine kinase E7Z58_18415 ENOG4105XJC Two component transcriptional regulator (Winged helix family E7Z58_18420 ENOG4105H4F exported protein E7Z58_18425 ENOG4105F4I Transcriptional regulator E7Z58_18430 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation E7Z58_18435 ENOG4105WJ3 XRE family Transcriptional regulator E7Z58_18440 ENOG4108J59 Extracellular solute-binding protein, family 5 E7Z58_18445 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E7Z58_18450 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase E7Z58_18455 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) E7Z58_18460 ENOG4105CCT upf0313 protein E7Z58_18470 ENOG4105ZKC Conserved Protein E7Z58_18475 ENOG4105CV8 reductase E7Z58_18480 ENOG4108I6A alcohol dehydrogenase E7Z58_18485 ENOG4105CF7 AraC family transcriptional regulator E7Z58_18490 ENOG4108K81 inner membrane protein YghB E7Z58_18495 ENOG4105C28 cystathionine E7Z58_18500 ENOG4105CWK Biopolymer transport protein, ExbB E7Z58_18505 ENOG4108ZZF transport protein (ExbD) E7Z58_18510 ENOG4105CYX Short-chain dehydrogenase reductase Sdr E7Z58_18520 ENOG4105CPC Aldo Keto reductase E7Z58_18530 ENOG410900S Protein of unknown function (DUF2623) E7Z58_18535 ENOG4105E3S small subunit E7Z58_18540 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E7Z58_18545 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit E7Z58_18550 ENOG4105DPX Hydrogenase, large subunit E7Z58_18555 ENOG4108USZ hydrogenase E7Z58_18560 ENOG4108WGS hydrogenase 2-specific chaperone E7Z58_18565 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E7Z58_18570 ENOG41082MF Hydrogenase assembly chaperone hypC hupF E7Z58_18575 ENOG4105CYM Glutathione S-transferase E7Z58_18580 ENOG4106032 Glutathionylspermidine synthase E7Z58_18585 ENOG4105CJ3 phosphate transporter E7Z58_18590 ENOG4108GH0 ATP-binding protein yghT E7Z58_18595 ENOG4108NDC ATP-binding protein yghS E7Z58_18600 ENOG4106FPV ATP-binding protein YghR E7Z58_18605 ENOG4108S55 polysaccharide biosynthesis protein E7Z58_18615 ENOG4108UUE Transcriptional regulator E7Z58_18620 ENOG4108M8S permease YjgP YjgQ family protein E7Z58_18630 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E7Z58_18635 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E7Z58_18645 ENOG4107RCI amp-dependent synthetase and ligase E7Z58_18655 ENOG4108KWP DNA-binding transcriptional regulator GlcC E7Z58_18660 ENOG4105CQB FAD linked oxidase domain protein E7Z58_18665 ENOG4105EU8 FAD linked oxidase domain protein E7Z58_18670 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E7Z58_18675 ENOG4108ZJF Glcg protein E7Z58_18680 ENOG4107QP3 malate synthase g E7Z58_18685 ENOG4105DAA L-lactate E7Z58_18695 ENOG4105PV3 Inner membrane protein yqiJ E7Z58_18710 ENOG4108TTM chaperone E7Z58_18725 ENOG41060ND LF82 chromosome, complete sequence E7Z58_18750 ENOG4108KZE transcriptional regulator E7Z58_18755 ENOG4108QDQ Ubiquinol-cytochrome C chaperone E7Z58_18790 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E7Z58_18820 ENOG4108UQV Membrane E7Z58_18825 ENOG4105CXN decarboxylase E7Z58_18830 ENOG4105EAA nucleoside E7Z58_18845 ENOG4105CEN a g-specific adenine glycosylase E7Z58_18855 ENOG41090ED Protein with unknown function (DUF469) E7Z58_18860 ENOG4105K33 Periplasmic Protein E7Z58_18865 ENOG4105HDK L-asparaginase E7Z58_18870 ENOG4106MH3 alpha helix chain E7Z58_18875 ENOG4105CSA Coproporphyrinogen iii oxidase E7Z58_18880 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) E7Z58_18890 ENOG4108VIA integral membrane protein E7Z58_18895 ENOG4105DFA alanine racemase domain protein E7Z58_18900 ENOG4105CZX twitching motility protein E7Z58_18915 ENOG4105D7Z glutathione synthase E7Z58_18920 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) E7Z58_18925 ENOG4105RWS endonuclease I E7Z58_18935 ENOG4107QNK )-transporter E7Z58_18960 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) E7Z58_18970 ENOG4108K0D peptidase, M48 E7Z58_18975 ENOG4105CV1 Transketolase (EC 2.2.1.1) E7Z58_18980 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia E7Z58_18985 ENOG4105CTS PTS system mannitol-specific E7Z58_18990 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein E7Z58_18995 ENOG4108Q8A Fructose-1,6-bisphosphatase E7Z58_19000 ENOG4108R4K DNA-binding, transcriptional regulator E7Z58_19005 ENOG4107Z1W Fructose transport system kinase E7Z58_19020 ENOG4105D2N Aldolase E7Z58_19025 ENOG4105D64 Mechanosensitive ion channel E7Z58_19030 ENOG4108ZUB Lysine exporter protein (Lyse ygga) E7Z58_19035 ENOG4105MPN Membrane E7Z58_19040 ENOG4105DEQ transcriptional regulator E7Z58_19045 ENOG4105CYC Transferase E7Z58_19050 ENOG4108M7F enoyl-CoA hydratase isomerase E7Z58_19055 ENOG4105DJT lAO AO transport system ATPase E7Z58_19060 ENOG4105D5P Methylmalonyl-coA mutase E7Z58_19080 ENOG4108JQ1 Dehydrogenase E7Z58_19090 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase E7Z58_19110 ENOG4107RAQ aminopeptidase E7Z58_19115 ENOG4105D0A hydroxylase E7Z58_19120 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E7Z58_19145 ENOG4105CYX Short-chain dehydrogenase reductase Sdr E7Z58_19150 ENOG4105CS2 ec 3.2.1.21 E7Z58_19155 ENOG4105N5Z UPF0267 protein E7Z58_19160 ENOG4108UT2 hemolysin iii E7Z58_19170 ENOG4105Y75 tpr repeat protein E7Z58_19175 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB E7Z58_19180 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) E7Z58_19185 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E7Z58_19190 ENOG4105T95 Thiol disulfide interChange protein E7Z58_19195 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) E7Z58_19205 ENOG4105CRK lysyL-tRNA synthetase E7Z58_19225 ENOG4105C2W permease E7Z58_19230 ENOG4105BZ8 glutamate synthase E7Z58_19235 ENOG4108R8B oxidoreductase Fe-S subunit E7Z58_19240 ENOG4105C7N Xanthine uracil vitamin C permease E7Z58_19245 ENOG4107QUY Guanine deaminase E7Z58_19250 ENOG4105C2W permease E7Z58_19255 ENOG4105C7W Xanthine dehydrogenase E7Z58_19260 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase E7Z58_19265 ENOG4107UUR Chlorohydrolase aminohydrolase E7Z58_19270 ENOG4105BZ8 glutamate synthase E7Z58_19275 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase E7Z58_19280 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC E7Z58_19285 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family E7Z58_19290 ENOG4105C5B carbamate kinase E7Z58_19300 ENOG4107S4Y M20 DapE family protein YgeY E7Z58_19305 ENOG4107RCH Diaminopropionate ammonia-lyase E7Z58_19310 ENOG4105IW6 Carbamoyltransferase E7Z58_19315 ENOG4108JUB Transcriptional regulator E7Z58_19320 ENOG4108UTP (2Fe-2S)-binding domain protein E7Z58_19325 ENOG4108HR6 Dehydrogenase E7Z58_19330 ENOG4105C7W Xanthine dehydrogenase E7Z58_19335 ENOG4108K5P (LipO)protein E7Z58_19355 ENOG4108MHD transport protein E7Z58_19360 ENOG4105CHU acetyl-coa acetyltransferase E7Z58_19370 ENOG4105CHR reductase E7Z58_19375 ENOG4107QNK )-transporter E7Z58_19385 ENOG4105RQF LysR family Transcriptional regulator E7Z58_19390 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) E7Z58_19395 ENOG41060NJ transcriptional regulator E7Z58_19410 ENOG4105CPC Aldo Keto reductase E7Z58_19415 ENOG4105SUV lipoprotein YgdR E7Z58_19420 ENOG4105EE5 Membrane protein terC E7Z58_19440 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase E7Z58_19455 ENOG4105IPU prepilin peptidase dependent protein A E7Z58_19460 ENOG4105JCS prepilin peptidase dependent protein E7Z58_19465 ENOG4105SEN Protein of unknown function (DUF2509) E7Z58_19470 ENOG4105RVB Prepilin peptidase dependent protein c E7Z58_19475 ENOG4105DSY exodeoxyribonuclease V, gamma E7Z58_19480 ENOG4107QXK peptidase E7Z58_19485 ENOG4107QKA exodeoxyribonuclease V beta E7Z58_19490 ENOG4107QYX exodeoxyribonuclease v alpha E7Z58_19495 ENOG4107QZM n-acetylglutamate synthase E7Z58_19500 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E7Z58_19520 ENOG4105CA3 membrane-bound lytic murein transglycosylase E7Z58_19525 ENOG4105CUZ uba thif-type nad fad binding protein E7Z58_19530 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) E7Z58_19535 ENOG4105C9B Cysteine desulfurase E7Z58_19540 ENOG4105M5B (LipO)protein E7Z58_19545 ENOG4105ETT transcriptional Regulator, LysR family E7Z58_19550 ENOG4105M08 Membrane E7Z58_19560 ENOG4107EDW L-fucose operon activator E7Z58_19570 ENOG4105CMG Carbohydrate kinase E7Z58_19580 ENOG4105EDR glucose galactose transporter E7Z58_19585 ENOG4107W7X Aldolase E7Z58_19590 ENOG4105C0A alcohol dehydrogenase E7Z58_19600 ENOG4105EJQ L-serine dehydratase E7Z58_19605 ENOG4105C44 Serine transporter E7Z58_19610 ENOG4105EWT decarboxylase family E7Z58_19625 ENOG4105WP7 tRNA pseudouridine synthase C E7Z58_19630 ENOG4105DR9 pseudouridine synthase E7Z58_19635 ENOG4105QDK Flavodoxin E7Z58_19640 ENOG4105DJB Major Facilitator Superfamily E7Z58_19645 ENOG4105EQX glucarate dehydratase E7Z58_19650 ENOG4105EQX glucarate dehydratase E7Z58_19655 ENOG4105BZU Histidine kinase E7Z58_19660 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) E7Z58_19665 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E7Z58_19670 ENOG4106A2Z transcriptional regulator antitoxin, MazE E7Z58_19675 ENOG4105MZG transcriptional modulator of maze toxin, mazf E7Z58_19680 ENOG4105DXN mazG family E7Z58_19695 ENOG4105HA9 of methanol dehydrogenase type E7Z58_19705 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) E7Z58_19710 ENOG4108CWB sugar kinase ygcE E7Z58_19715 ENOG4108ITV Inner membrane protein yqcE E7Z58_19720 ENOG4105CHR reductase E7Z58_19725 ENOG4107R3A FAD linked oxidase domain protein E7Z58_19730 ENOG4105C54 Major Facilitator superfamily E7Z58_19735 ENOG4106IKH Electron transfer flavoprotein E7Z58_19740 ENOG4105YBM electron transfer flavoprotein subunit ygcQ E7Z58_19745 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator E7Z58_19750 ENOG4105WQV ferredoxin-like protein E7Z58_19755 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E7Z58_19760 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase E7Z58_19770 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) E7Z58_19785 ENOG4105DTT CRISPR-associated helicase, cas3 E7Z58_19790 ENOG4105CYR Crispr-associated protein, cse1 family E7Z58_19795 ENOG41061HK CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) E7Z58_19800 ENOG41060M0 Crispr-associated protein, cse4 family E7Z58_19805 ENOG4108VWQ crispr-associated protein E7Z58_19810 ENOG4108Y7V CRISPR-associated protein, Cse3 family E7Z58_19815 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) E7Z58_19820 ENOG4105PWE CRISPR-associated protein cas2 E7Z58_19825 ENOG4108MXK alkaline phosphatase isozyme conversion E7Z58_19835 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) E7Z58_19840 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) E7Z58_19845 ENOG4105N0Z inner membrane protein ygbE E7Z58_19880 ENOG4108K5P (LipO)protein E7Z58_19885 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E7Z58_19890 ENOG4105C6Z Gluconate E7Z58_19895 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) E7Z58_19900 ENOG4105FB2 class II Aldolase E7Z58_19905 ENOG4105G63 Type III effector Hrp-dependent E7Z58_19910 ENOG4105ZXK Dehydrogenase E7Z58_19915 ENOG4105MVE transcriptional regulator E7Z58_19920 ENOG4105MEW serine threonine protein phosphatase E7Z58_19925 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) E7Z58_19935 ENOG4105VXR cytoplasmic protein E7Z58_19940 ENOG4108JUA Transcriptional regulator E7Z58_19945 ENOG4105C45 hydrogenase expression formation protein (HypE) E7Z58_19950 ENOG4105CQS hydrogenase expression formation protein HypD E7Z58_19955 ENOG41083WG hydrogenase assembly chaperone E7Z58_19960 ENOG4107RSS Hydrogenase accessory protein HypB E7Z58_19965 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E7Z58_19975 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA E7Z58_19980 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) E7Z58_19985 ENOG4107R30 NADH dehydrogenase E7Z58_19990 ENOG4107TDF Formate hydrogenlyase subunit 4 E7Z58_19995 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E7Z58_20000 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit E7Z58_20005 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit E7Z58_20010 ENOG4105I6X formate hydrogenlyase maturation E7Z58_20015 ENOG4108MG9 hydrogenase 3 maturation protease E7Z58_20020 ENOG4105CS2 ec 3.2.1.21 E7Z58_20025 ENOG4105C5Y PTS System E7Z58_20030 ENOG4105DDV Transcriptional regulator (LacI family E7Z58_20035 ENOG4108RC0 Electron transport protein E7Z58_20040 ENOG4105C8H hydrogenase maturation protein Hypf E7Z58_20060 ENOG4105C2X Arabinose 5-phosphate isomerase E7Z58_20065 ENOG410804X Transcriptional regulator E7Z58_20070 ENOG4105J92 DNA-binding transcriptional activator GutM E7Z58_20075 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase E7Z58_20080 ENOG4105VI0 Pts system, glucitol sorbitol-specific E7Z58_20085 ENOG4105DZY Pts system, glucitol sorbitol-specific E7Z58_20090 ENOG410787A Pts system, glucitol sorbitol-specific E7Z58_20095 ENOG4105CVE Lytic murein transglycosylase E7Z58_20100 ENOG4107TH8 cina domain protein E7Z58_20115 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) E7Z58_20120 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) E7Z58_20150 ENOG4107VXZ Hydrolase E7Z58_20155 ENOG4105W39 Membrane E7Z58_20170 ENOG4105C0R drug resistance transporter emrb qaca subfamily E7Z58_20175 ENOG4105CW7 secretion protein, HlyD family E7Z58_20180 ENOG4105NTK Transcriptional repressor Mpra E7Z58_20185 ENOG4105ZED uncharacterized protein ygaH E7Z58_20190 ENOG4108UMN azlc family E7Z58_20205 ENOG4105GIJ Glycine betaine E7Z58_20210 ENOG4108HQS Glycine betaine E7Z58_20215 ENOG4108IJ7 Glycine betaine E7Z58_20230 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E7Z58_20235 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) E7Z58_20240 ENOG4105WAZ (Glutaredoxin-like protein) NrdH E7Z58_20245 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) E7Z58_20250 ENOG4108WMJ Protein of unknown function (DUF2002) E7Z58_20255 ENOG4108RNS Exports L-alanine (By similarity) E7Z58_20260 ENOG4108X73 DNA- binding protein E7Z58_20265 ENOG4108V62 Rhodanese domain protein E7Z58_20270 ENOG41080HT Transcriptional regulator, arsr family E7Z58_20275 ENOG4105VPI YqaE family transport protein E7Z58_20280 ENOG4109066 lysm domain bon superfamily protein E7Z58_20285 ENOG4108PVQ transcriptional regulator E7Z58_20290 ENOG4105C85 amino acid E7Z58_20295 ENOG4108JPW Aminotransferase E7Z58_20300 ENOG4105C26 Dehydrogenase E7Z58_20305 ENOG4105D5U fad dependent oxidoreductase E7Z58_20320 ENOG4105E54 alpha-amylase E7Z58_20345 ENOG4108MGN ATP-binding component of a transport system E7Z58_20405 ENOG4105DFP Integrase E7Z58_20420 ENOG4108Z1B Cyclase dehydrase E7Z58_20425 ENOG4105VDB UPF0125 protein E7Z58_20430 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E7Z58_20435 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) E7Z58_20455 ENOG4108JU6 CBS domain protein E7Z58_20460 ENOG4106KVJ cytochrome C assembly protein E7Z58_20465 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY E7Z58_20490 ENOG41090EK ompa motb domain protein E7Z58_20495 ENOG4108KHX Diguanylate cyclase E7Z58_20500 ENOG4108WS1 E7Z58_20505 ENOG4105QP9 Protein of unknown function (DUF2799) E7Z58_20510 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E7Z58_20515 ENOG4105EHE chorismate mutase- prephenate dehydrogenase E7Z58_20520 ENOG4105CQC Prephenate dehydratase E7Z58_20530 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA E7Z58_20535 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane E7Z58_20540 ENOG4105C34 Pseudouridine synthase E7Z58_20545 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase E7Z58_20550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E7Z58_20575 ENOG4105CSH Transporter E7Z58_20580 ENOG4105T42 (LipO)protein E7Z58_20585 ENOG4105JIM Phosphatidylserine synthase E7Z58_20590 ENOG4105CD5 CoA-binding domain protein E7Z58_20595 ENOG4106IUH DTW domain containing protein E7Z58_20600 ENOG4105K63 Thioredoxin E7Z58_20605 ENOG4105EIB trna rrna methyltransferase E7Z58_20625 ENOG41090KR LysR family transcriptional Regulator E7Z58_20630 ENOG4105C1J atp-dependent rna helicase E7Z58_20635 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) E7Z58_20640 ENOG4108IYU L-aspartate oxidase E7Z58_20650 ENOG4105EMN RNA polymerase sigma factor E7Z58_20655 ENOG41069PW sigma-e factor negative regulatory protein E7Z58_20660 ENOG4105VQK sigma E regulatory protein, MucB RseB E7Z58_20665 ENOG4105WMJ Positive regulator of sigma E, RseC MucC E7Z58_20675 ENOG4105C3F Signal peptidase i E7Z58_20695 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) E7Z58_20710 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding E7Z58_20715 ENOG4106G6Q Transcriptional regulator E7Z58_20720 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB E7Z58_20725 ENOG4108Z6B deaminase E7Z58_20740 ENOG4107WP9 Histidine kinase E7Z58_20745 ENOG4108SKK alpha helix protein E7Z58_20750 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E7Z58_20755 ENOG4108YZA Nitrogen regulatory protein pii E7Z58_20760 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E7Z58_20770 ENOG4108NZE NAGC-like transcriptional regulator E7Z58_20775 ENOG4107HQ7 repeat protein E7Z58_20780 ENOG4105FCA ABC transporter periplasmic-binding protein YphF E7Z58_20785 ENOG4108F37 ATP-binding component of a transport system E7Z58_20790 ENOG4105CNN ABC, transporter E7Z58_20795 ENOG4105CPQ Dehydrogenase E7Z58_20800 ENOG4108ZKT aldose 1-epimerase E7Z58_20805 ENOG4108SB3 DoxX Family E7Z58_20830 ENOG4105FUY alpha subunit E7Z58_20835 ENOG4108W5M transcriptional regulator E7Z58_20840 ENOG4105D8G Major Facilitator superfamily E7Z58_20845 ENOG4108MN2 Stationary phase inducible protein CsiE E7Z58_20850 ENOG4107XM9 (LipO)protein E7Z58_20875 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins E7Z58_20895 ENOG4108ZIT Ferredoxin, 2FE-2S E7Z58_20900 ENOG4105WVQ Fe-S assembly protein IscX E7Z58_20910 ENOG4105YYA enhanced serine sensitivity protein SseB E7Z58_20915 ENOG4105KHC sulfurtransferase E7Z58_20920 ENOG4105DN3 alpha-2-macroglobulin domain protein E7Z58_20925 ENOG4108JQB penicillin-binding protein 1C E7Z58_20955 ENOG4105N21 Membrane E7Z58_20970 ENOG4105VPD cellular component movement E7Z58_20980 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) E7Z58_20990 ENOG41066DY Membrane E7Z58_20995 ENOG4108ZMA Outer membrane lipoprotein E7Z58_21000 ENOG41062G3 Protein of unknown function (DUF2633) E7Z58_21005 ENOG4105BZU Histidine kinase E7Z58_21010 ENOG4105C9X ppx gppa phosphatase E7Z58_21015 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) E7Z58_21020 ENOG4108V3E phosphoribosylglycinamide formyltransferase E7Z58_21035 ENOG4105C2W permease E7Z58_21045 ENOG4105K89 arsenate reductase E7Z58_21050 ENOG4105ERG peptidase m48, ste24p E7Z58_21055 ENOG4105C02 permease E7Z58_21060 ENOG4105TMB Formate nitrite transporter E7Z58_21065 ENOG4105TMB Formate nitrite transporter E7Z58_21070 ENOG4108JUA Transcriptional regulator E7Z58_21075 ENOG4105I6X formate hydrogenlyase maturation E7Z58_21080 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit E7Z58_21090 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E7Z58_21100 ENOG4107WQX hydrogenase 4 membrane subunit E7Z58_21105 ENOG4105D65 subunit l E7Z58_21110 ENOG4107TDF Formate hydrogenlyase subunit 4 E7Z58_21120 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) E7Z58_21125 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E7Z58_21130 ENOG4105RH4 Glycine cleavage system transcriptional repressor E7Z58_21140 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E7Z58_21150 ENOG4105CGZ zinc metallopeptidase E7Z58_21155 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) E7Z58_21160 ENOG4106KED esterase YpfH E7Z58_21175 ENOG4105KUZ arsenate reductase E7Z58_21185 ENOG4105BZS acriflavin resistance protein E7Z58_21190 ENOG4105BZU Histidine kinase E7Z58_21195 ENOG4105BZ8 glutamate synthase E7Z58_21200 ENOG4107VIJ nudix hydrolase E7Z58_21205 ENOG4108PVD exported protein E7Z58_21210 ENOG4105CV1 Transketolase (EC 2.2.1.1) E7Z58_21215 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) E7Z58_21220 ENOG4105C6K Malic enzyme E7Z58_21225 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place E7Z58_21230 ENOG4106S4J ethanolamine utilization protein EutP E7Z58_21235 ENOG4105NDK ethanolamine utilization protein E7Z58_21240 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase E7Z58_21245 ENOG4107WUY phosphate acetyltransferase E7Z58_21250 ENOG4105KNY Microcompartments protein E7Z58_21255 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml E7Z58_21260 ENOG4108EKI Dehydrogenase E7Z58_21265 ENOG4107RWI ethanolamine utilization protein eutJ E7Z58_21270 ENOG4105C0A alcohol dehydrogenase E7Z58_21280 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase E7Z58_21285 ENOG4105CPD ethanolamine ammonia-lyase E7Z58_21295 ENOG4106D67 ethanolamine utilization protein E7Z58_21300 ENOG4108X49 Ethanolamine utilization protein EutK E7Z58_21305 ENOG4108K3Z AraC family transcriptional regulator E7Z58_21315 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase E7Z58_21320 ENOG4108R6G acetyltransferase E7Z58_21325 ENOG4105QZU Inner membrane protein YfeZ E7Z58_21330 ENOG4105E7K (LipO)protein E7Z58_21335 ENOG4105EZR dyp-type peroxidase family protein E7Z58_21340 ENOG4107S1E Beta-lactamase E7Z58_21345 ENOG4105C5Y PTS System E7Z58_21360 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr E7Z58_21365 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein E7Z58_21370 ENOG4108I5D sulfate abc transporter E7Z58_21375 ENOG4105ECW sulfate abc transporter E7Z58_21380 ENOG4108IJ6 ABC transporter E7Z58_21385 ENOG4105C6T cysteine synthase E7Z58_21390 ENOG4105WEC Molybdate metabolism regulator E7Z58_21395 ENOG4105M0Y E7Z58_21405 ENOG4105C5Y PTS System E7Z58_21410 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E7Z58_21415 ENOG4105KZ7 phosphocarrier protein hpr E7Z58_21420 ENOG4105C6T cysteine synthase E7Z58_21435 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) E7Z58_21440 ENOG4105VRT cytoplasmic protein E7Z58_21445 ENOG4105DHU Bile acid E7Z58_21450 ENOG4108M0I Transcriptional regulator E7Z58_21455 ENOG4108NFH Sugar hydrolase E7Z58_21460 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) E7Z58_21465 ENOG4105EAA nucleoside E7Z58_21475 ENOG4105CN8 Transcriptional regulator E7Z58_21510 ENOG4105GXM Putative transcription regulator (DUF1323) E7Z58_21515 ENOG4105HZG regulatoR E7Z58_21530 ENOG4108KMM Diguanylate cyclase E7Z58_21535 ENOG4105D9N nucleoside E7Z58_21545 ENOG4109076 Conserved Protein E7Z58_21550 ENOG4105VCT ion-transport protein YfeO E7Z58_21560 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) E7Z58_21565 ENOG410863U PTS System E7Z58_21570 ENOG4105DC7 peptidase M24 E7Z58_21575 ENOG4105CN9 Peptidase m42 family protein E7Z58_21585 ENOG4108CIP transcriptional regulator E7Z58_21590 ENOG4105DY9 regulatoR E7Z58_21595 ENOG4108HRK Histidine kinase E7Z58_21600 ENOG4105CHM Aminotransferase E7Z58_21610 ENOG4105D1S lipid A biosynthesis E7Z58_21615 ENOG4105W9M Membrane E7Z58_21625 ENOG4108V08 YfdX protein E7Z58_21635 ENOG4105CFN oxalyl-CoA decarboxylase E7Z58_21640 ENOG4108N2Y auxin Efflux E7Z58_21645 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F E7Z58_21650 ENOG4105BZU Histidine kinase E7Z58_21655 ENOG4108WQH regulatoR E7Z58_21660 ENOG4105CW7 secretion protein, HlyD family E7Z58_21665 ENOG4105C0R drug resistance transporter emrb qaca subfamily E7Z58_21675 ENOG4105C6Z Gluconate E7Z58_21680 ENOG4105W8I Transcriptional regulator E7Z58_21685 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision E7Z58_21745 ENOG4108UUM single-stranded DNA-binding protein E7Z58_21750 ENOG4105VIZ double-strand break repair protein E7Z58_21825 ENOG4105CDU Replicative dna helicase E7Z58_21855 ENOG4105NY2 NinB protein E7Z58_21885 ENOG4105RWQ Protein of unknown function (DUF1364) E7Z58_21925 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 E7Z58_21935 ENOG4106050 phage regulatory protein, rha family E7Z58_21950 ENOG4108N0N Phage Terminase Large Subunit E7Z58_22025 ENOG4105DFP Integrase E7Z58_22035 ENOG4105S64 Formate nitrite transporter E7Z58_22040 ENOG410903C (LipO)protein E7Z58_22050 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation E7Z58_22055 ENOG4105KZW UPF0381 protein E7Z58_22070 ENOG4108BY2 phosphohistidine phosphatase E7Z58_22085 ENOG4108FZ9 Chaperone E7Z58_22090 ENOG4105NEV Fimbrial E7Z58_22095 ENOG4105UGQ Fimbrial E7Z58_22100 ENOG4105US4 fimbrial-like protein yfcP E7Z58_22115 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) E7Z58_22130 ENOG4105EJ9 Membrane E7Z58_22135 ENOG4108BPE -transporting atpase E7Z58_22140 ENOG4105MH2 YfcL protein E7Z58_22145 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) E7Z58_22150 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E7Z58_22155 ENOG4105F9N Major Facilitator Superfamily E7Z58_22160 ENOG4106WZ1 flagella biosynthesis regulator E7Z58_22165 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) E7Z58_22170 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E7Z58_22180 ENOG4105DQR SNARE associated Golgi E7Z58_22190 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase E7Z58_22195 ENOG4108S3P Sporulation domain protein E7Z58_22200 ENOG4105E96 Colicin v production protein E7Z58_22205 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase E7Z58_22210 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase E7Z58_22215 ENOG4105E89 ABC transporter E7Z58_22220 ENOG4105E89 ABC transporter E7Z58_22225 ENOG4105DSP amino acid AbC transporter E7Z58_22230 ENOG4106YG3 ABC transporter E7Z58_22235 ENOG4108JEH abc transporter atp-binding protein E7Z58_22240 ENOG4105DNE Transposase E7Z58_22245 ENOG4105ECP epimerase E7Z58_22250 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase E7Z58_22255 ENOG4105CYM Glutathione S-transferase E7Z58_22260 ENOG4108SHQ Glutathione S-transferase E7Z58_22265 ENOG4108RE9 Phosphodiesterase E7Z58_22270 ENOG4105PTV Nudix Hydrolase E7Z58_22275 ENOG4105CSX c4-dicarboxylate anaerobic carrier E7Z58_22280 ENOG4105C6K Malic enzyme E7Z58_22285 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E7Z58_22300 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 E7Z58_22305 ENOG4107QWE )-transporter E7Z58_22315 ENOG4105CHM Aminotransferase E7Z58_22320 ENOG4107NQ8 LysR family Transcriptional regulator E7Z58_22335 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E7Z58_22340 ENOG4105GKE subunit e E7Z58_22345 ENOG4107QIZ NADH dehydrogenase E7Z58_22350 ENOG4107R0R NADH dehydrogenase subunit g E7Z58_22360 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E7Z58_22365 ENOG4107UFS subunit j E7Z58_22370 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E7Z58_22375 ENOG4105D65 subunit l E7Z58_22380 ENOG4105C8S subunit m E7Z58_22390 ENOG4106HDC E7Z58_22400 ENOG4106EES E7Z58_22405 ENOG4105ZD8 E7Z58_22410 ENOG4105GDX Domain of unknown function (DUF1877) E7Z58_22415 ENOG4107VAM peptidase, m28 E7Z58_22420 ENOG4105CP2 von willebrand factor, type a E7Z58_22425 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is E7Z58_22435 ENOG4107YB6 acetyltransferase, (GNAT) family E7Z58_22440 ENOG4105TNS Conserved Protein E7Z58_22445 ENOG4105E4F Isochorismate synthase E7Z58_22460 ENOG4108IPT Naphthoate synthase E7Z58_22465 ENOG4105DNI Converts SHCHC to OSB (By similarity) E7Z58_22470 ENOG4105CEY Amp-dependent synthetase and ligase E7Z58_22475 ENOG4106GZG polymyxin resistance protein B E7Z58_22480 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) E7Z58_22490 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) E7Z58_22495 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) E7Z58_22525 ENOG4108UII YfaZ family E7Z58_22535 ENOG4107258 Transcriptional regulator E7Z58_22545 ENOG4105CSP Major Facilitator Superfamily E7Z58_22560 ENOG4105DNE Transposase E7Z58_22565 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E7Z58_22575 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A E7Z58_22580 ENOG4105CXY transporter E7Z58_22585 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase E7Z58_22595 ENOG4105FQR PH-inducible protein involved in stress response E7Z58_22600 ENOG4105XPH Ferredoxin E7Z58_22605 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E7Z58_22610 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E7Z58_22615 ENOG4107GHC outer membrane autotransporter E7Z58_22625 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E7Z58_22630 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) E7Z58_22635 ENOG4108QJJ Protein of unknown function (DUF1175) E7Z58_22640 ENOG4107S52 alpha-2-macroglobulin domain protein E7Z58_22645 ENOG41081SK signal peptide protein E7Z58_22650 ENOG4105EDV vault protein E7Z58_22655 ENOG4105CHU acetyl-coa acetyltransferase E7Z58_22660 ENOG4105CRW Short chain fatty acid transporter E7Z58_22665 ENOG4107QNJ CoA-transferase subunit B E7Z58_22670 ENOG4107QP7 CoA-transferase subunit A E7Z58_22675 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E7Z58_22680 ENOG4105BZU Histidine kinase E7Z58_22685 ENOG4105BZU Histidine kinase E7Z58_22690 ENOG41068CG regulatoR E7Z58_22695 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC E7Z58_22700 ENOG4105FCK Membrane E7Z58_22705 ENOG4105CJ2 (LipO)protein E7Z58_22710 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E7Z58_22715 ENOG4105CF1 Alkylated DNA repair protein E7Z58_22720 ENOG4105IBP Cyclic peptide transporter E7Z58_22735 ENOG4108ZNS ferredoxin-type protein NapF E7Z58_22740 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase E7Z58_22750 ENOG4108BGM Quinol dehydrogenase periplasmic component E7Z58_22755 ENOG4105GXZ Ferredoxin-type protein NapH E7Z58_22760 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) E7Z58_22765 ENOG4105CUW cytochrome C-TYPE protein E7Z58_22770 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) E7Z58_22775 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) E7Z58_22780 ENOG41060IM Heme exporter protein E7Z58_22785 ENOG4105X3C heme exporter protein E7Z58_22795 ENOG4105DA4 cytochrome c-type biogenesis protein E7Z58_22800 ENOG4107QX9 Thiol disulfide interChange protein E7Z58_22805 ENOG4105KWW Biogenesis protein E7Z58_22810 ENOG4105WH1 Two component transcriptional regulator luxr family E7Z58_22815 ENOG4108MGN ATP-binding component of a transport system E7Z58_22825 ENOG4105E68 Sulfatase E7Z58_22845 ENOG4105CFI type iii restriction protein res subunit E7Z58_22850 ENOG4105I08 Pseudouridine synthase E7Z58_22855 ENOG4105C2C drug resistance transporter, Bcr CflA E7Z58_22860 ENOG4105HG6 E7Z58_22865 ENOG4108JQ5 ABC transporter E7Z58_22870 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component E7Z58_22875 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component E7Z58_22880 ENOG4105E43 Extracellular solute-binding protein, family 5 E7Z58_22885 ENOG4105CXC rtn protein E7Z58_22890 ENOG4107TT5 NLP P60 protein E7Z58_22895 ENOG41076MN Phosphoesterase, PA-phosphatase related E7Z58_22900 ENOG4105CKI cobalamin synthesis protein E7Z58_22905 ENOG4105DEI Mannitol dehydrogenase E7Z58_22915 ENOG4105KRS Proteinase inhibitor E7Z58_22920 ENOG4105S8Q sugar efflux transporter E7Z58_22925 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein E7Z58_22930 ENOG4105DE4 1-phosphofructokinase E7Z58_22935 ENOG4105DM4 PTS System E7Z58_22945 ENOG4105DD7 kinase (PfkB family E7Z58_22950 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) E7Z58_22955 ENOG4105D9N nucleoside E7Z58_22960 ENOG4108Y4K DNA-binding transcriptional activator E7Z58_22970 ENOG4105D9N nucleoside E7Z58_22975 ENOG4105DD7 kinase (PfkB family E7Z58_22980 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) E7Z58_22985 ENOG4105HMI Membrane E7Z58_22990 ENOG4105DUM transcriptional regulator, lysR family E7Z58_22995 ENOG4108IQI permease E7Z58_23000 ENOG4105D05 Receptor E7Z58_23005 ENOG4105C4W S-formylglutathione hydrolase E7Z58_23015 ENOG4105DHF Membrane E7Z58_23020 ENOG41060NJ transcriptional regulator E7Z58_23025 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator E7Z58_23030 ENOG4105C2J ABC transporter E7Z58_23035 ENOG4108HWV )-transporter E7Z58_23040 ENOG4107SJI Dehydrogenase E7Z58_23045 ENOG4105BZ8 glutamate synthase E7Z58_23050 ENOG4105Y9N Membrane E7Z58_23055 ENOG4107GZ4 SanA protein E7Z58_23065 ENOG41067MG lrgb family E7Z58_23075 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) E7Z58_23090 ENOG4105H9W Short-chain dehydrogenase reductase Sdr E7Z58_23095 ENOG4105KHU inner membrane protein YohD E7Z58_23100 ENOG41069YE inner membrane protein yohC E7Z58_23105 ENOG41061WM D-Alanyl-D-Alanine E7Z58_23110 ENOG4105CXG d-lactate dehydrogenase E7Z58_23115 ENOG4107QK4 glycoside hydrolase, family 3 domain protein E7Z58_23120 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system E7Z58_23125 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component E7Z58_23130 ENOG4108IJ8 ABC transporter E7Z58_23135 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component E7Z58_23145 ENOG4108XDN Transcriptional regulator E7Z58_23150 ENOG4108HRK Histidine kinase E7Z58_23155 ENOG4108NEV two component transcriptional regulator, LytTR family E7Z58_23160 ENOG4108W15 Protein of unknown function (DUF1456) E7Z58_23165 ENOG4108YCW (LipO)protein E7Z58_23170 ENOG410903U zinc ion binding E7Z58_23175 ENOG4105DEG Vwa containing coxe family protein E7Z58_23180 ENOG4105RD5 E7Z58_23185 ENOG4105KKX ATPase associated with various cellular activities aaa_5 E7Z58_23195 ENOG4108KDT Molybdate metabolism regulator E7Z58_23200 ENOG4108KDT Molybdate metabolism regulator E7Z58_23210 ENOG4105D1F ATP-binding protein E7Z58_23215 ENOG41067AK Protein of unknown function (DUF2574) E7Z58_23220 ENOG41063W2 Fimbrial protein E7Z58_23225 ENOG4108MQF Chaperone E7Z58_23230 ENOG4105CW0 outer membrane usher protein E7Z58_23235 ENOG410662B Type-1 fimbrial protein E7Z58_23240 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly E7Z58_23245 ENOG41061MD high-affinity nickel-transporter E7Z58_23260 ENOG4105DWF phosphomethylpyrimidine kinase E7Z58_23265 ENOG4108UQ1 hydrolase, family 25 E7Z58_23270 ENOG4105FDP GntR family transcriptional regulator E7Z58_23275 ENOG4108TFM Kinase, PfkB family E7Z58_23280 ENOG4108KD5 ADP-ribosylation crystallin J1 E7Z58_23285 ENOG4105EAA nucleoside E7Z58_23290 ENOG4105EIE fructose-bisphosphate aldolase E7Z58_23305 ENOG41082GB PTS system galactitol-specific transporter subunit IIA E7Z58_23310 ENOG41090UW PTS System E7Z58_23315 ENOG4105DT3 PTS system, galactitol-specific IIc component E7Z58_23320 ENOG4107WTH Galactitol-1-phosphate dehydrogenase E7Z58_23335 ENOG41076Z6 Uncharacterized protein yegR E7Z58_23345 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E7Z58_23620 ENOG41073YN Protein of unknown function (DUF1380) E7Z58_23670 ENOG4105FEQ ParB domain protein nuclease E7Z58_23800 ENOG4105K4U addiction module toxin, RelE StbE family E7Z58_23820 ENOG4105KF5 hemolysin expression-modulating protein E7Z58_23915 ENOG4105CZX twitching motility protein E7Z58_23970 ENOG4105K5T PilT protein E7Z58_23985 ENOG4107QHF type ii secretion system protein e E7Z58_24075 ENOG4105VDM plasmid maintenance system antidote protein, xre family E7Z58_24140 ENOG4108V42 Type IV secretion system protein VirB8 E7Z58_24150 ENOG4105CMA conjugation trbi family protein E7Z58_24155 ENOG4108EHY type IV secretion system E7Z58_24280 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor E7Z58_24310 ENOG4108KTG Membrane protein, drug metabolite transporter E7Z58_24330 ENOG4105BZU Histidine kinase