locus-tag class description HVW55_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HVW55_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HVW55_00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HVW55_00030 ENOG410667J hydrolase HVW55_00035 ENOG410657R replicase EC 2.7 HVW55_00040 ENOG4107WAP fad NAD(P)-binding domain HVW55_00045 ENOG4105D99 atp gtp-binding protein HVW55_00050 ENOG4105R2A (LipO)protein HVW55_00070 ENOG4105FDP GntR family transcriptional regulator HVW55_00075 ENOG4105CI1 PTS System HVW55_00080 ENOG4105F8D glycoside hydrolase family 4 HVW55_00085 ENOG4108AHD Transcriptional regulator HVW55_00090 ENOG4107RUZ Sss sodium solute transporter superfamily HVW55_00095 ENOG4105CBG Sulfatase HVW55_00100 ENOG4106DRA Inner membrane protein YidI HVW55_00105 ENOG4105VG5 Membrane HVW55_00110 ENOG4105JP4 Inner membrane protein yidG HVW55_00115 ENOG4105J13 transcriptional regulator HVW55_00120 ENOG4105E5M Multidrug resistance protein D HVW55_00135 ENOG4105C7K acetolactate synthase HVW55_00140 ENOG4105M71 acetolactate synthase 1 regulatory subunit HVW55_00155 ENOG4108KX4 response regulator HVW55_00160 ENOG4105BZU Histidine kinase HVW55_00165 ENOG4105CXY transporter HVW55_00170 ENOG4105CXY transporter HVW55_00175 ENOG4108SAJ Protein of unknown function (DUF1198) HVW55_00185 ENOG4105VCP PTS System HVW55_00190 ENOG4105CS2 ec 3.2.1.21 HVW55_00195 ENOG4105CK1 PTS System HVW55_00205 ENOG4105ETE Transcriptional regulator (LacI family HVW55_00220 ENOG4105C7N Xanthine uracil vitamin C permease HVW55_00225 ENOG4108SAJ Protein of unknown function (DUF1198) HVW55_00245 ENOG4105TNG K13735 adhesin invasin HVW55_00250 ENOG4108YAB Invasion protein HVW55_00255 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC HVW55_00280 ENOG4105T8A Uncharacterized protein YicS HVW55_00285 ENOG4105D01 (LipO)protein HVW55_00290 ENOG4108UZ3 Transporter HVW55_00295 ENOG4105S8Q sugar efflux transporter HVW55_00355 ENOG4105DFP Integrase HVW55_00365 ENOG4105CT4 transporter HVW55_00370 ENOG4105CJQ hydrolase, family 31 HVW55_00375 ENOG4105JV1 AsmA family HVW55_00380 ENOG4105C2W permease HVW55_00385 ENOG4105D6U Sodium Glutamate Symporter HVW55_00390 ENOG4105CB5 ATP-dependent DNA helicase recG HVW55_00395 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HVW55_00400 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HVW55_00410 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HVW55_00420 ENOG4105EN6 Membrane HVW55_00430 ENOG4105DSJ YicC domain protein HVW55_00450 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HVW55_00455 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HVW55_00465 ENOG4105KDC 50s ribosomal protein l28 HVW55_00485 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HVW55_00490 ENOG4105DKP glycosyl transferase, family 9 HVW55_00495 ENOG4107RJ7 Glycosyl transferase (Group 1 HVW55_00500 ENOG4107543 (lipo)polysaccharide HVW55_00510 ENOG4107XU6 Glycosyl transferase (Group 1 HVW55_00515 ENOG4106AH0 Glycosyl Transferase HVW55_00520 ENOG4105X1N Glycosyl transferase family 8 HVW55_00525 ENOG4108PDR lipopolysaccharide core biosynthesis protein HVW55_00530 ENOG4108QD8 lipopolysaccharide core biosynthesis protein HVW55_00535 ENOG4108XNZ glycosyl transferase HVW55_00540 ENOG41068PG O-Antigen polymerase HVW55_00545 ENOG4105D16 lipopolysaccharide heptosyltransferase i HVW55_00550 ENOG4105XA0 heptosyltransferase ii HVW55_00560 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HVW55_00570 ENOG4105K64 Glycosyl transferase, family 2 HVW55_00575 ENOG4105PXI polysaccharide deacetylase HVW55_00580 ENOG41063SB peptidase HVW55_00590 ENOG4107YZP Rhodanese domain protein HVW55_00595 ENOG4105VW4 glutaredoxin 3 HVW55_00610 ENOG4105D7W serine acetyltransferase HVW55_00615 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HVW55_00625 ENOG41073TP transcriptional regulator HVW55_00630 ENOG4105DAA L-lactate HVW55_00635 ENOG4105EUR Domain-Containing protein HVW55_00640 ENOG4108WY4 inner membrane lipoprotein HVW55_00645 ENOG4108YYI Protein of unknown function (DUF2810) HVW55_00655 ENOG4105E61 Mannitol repressor protein HVW55_00665 ENOG4105CTS PTS system mannitol-specific HVW55_00670 ENOG4105FP6 Protein of unknown function (DUF3302) HVW55_00675 ENOG4105EFX secretion protein, HlyD family HVW55_00680 ENOG4108U78 Glutathione S-transferase HVW55_00690 ENOG4105EM7 Selenocysteine-specific translation elongation factor HVW55_00695 ENOG4105C0A alcohol dehydrogenase HVW55_00700 ENOG4105C26 Dehydrogenase HVW55_00710 ENOG4105KK7 inner membrane protein YiaW HVW55_00715 ENOG4105EFX secretion protein, HlyD family HVW55_00720 ENOG4108Q2M Transcriptional regulator HVW55_00725 ENOG4105GNX MltA-interacting MipA family protein HVW55_00735 ENOG4105CT4 transporter HVW55_00745 ENOG4105J4Q Transcriptional regulator HVW55_00750 ENOG4108XIB electron transport protein ysaA HVW55_00755 ENOG4105JKW Valine--pyruvate aminotransferase HVW55_00760 ENOG4107T9C Alpha amylase catalytic region HVW55_00765 ENOG4108UR8 BAX protein HVW55_00770 ENOG4105T16 Transcriptional regulator (AraC family) HVW55_00775 ENOG4108HWW ABC transporter HVW55_00785 ENOG4105DFW ABC transporter HVW55_00795 ENOG4105CMG Carbohydrate kinase HVW55_00800 ENOG410688U Inner membrane protein yiaB HVW55_00810 ENOG4105MEV Acyl-transferase HVW55_00830 ENOG41060TC Hok gef cell toxic protein HVW55_00840 ENOG4105MVF Transcriptional regulator HVW55_00845 ENOG4106JH6 (LipO)protein HVW55_00855 ENOG4108ZG0 Ompa motb domain protein HVW55_00860 ENOG4107QY8 reductase HVW55_00865 ENOG4105HNP -acetyltransferase HVW55_00870 ENOG4108R3E Dna-3-methyladenine glycosylase i HVW55_00875 ENOG4105EAX Putative lipase HVW55_00880 ENOG4105FCD Major Facilitator HVW55_00885 ENOG4106EAR Fimbrial protein HVW55_00890 ENOG4108VCD Chaperone HVW55_00895 ENOG4105CW0 outer membrane usher protein HVW55_00900 ENOG4105MHR Fimbrial protein HVW55_00905 ENOG4106UCC Fimbrial protein HVW55_00910 ENOG4105DIJ Phosphoethanolamine transferase HVW55_00920 ENOG4105DEF Extracellular solute-binding protein, family 5 HVW55_00925 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HVW55_00930 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HVW55_00935 ENOG4105C3U ABC transporter HVW55_00940 ENOG4108JQ7 (ABC) transporter HVW55_00945 ENOG4105C44 Serine transporter HVW55_00960 ENOG4105D1V cellulose synthase operon protein YhjU HVW55_00965 ENOG4105WQA Cellulose biosynthesis protein BcsF HVW55_00970 ENOG4105U74 cellulose biosynthesis protein BcsE HVW55_00975 ENOG410661M cytoplasmic protein HVW55_00985 ENOG4107QZ7 Cellulose synthase catalytic subunit HVW55_00990 ENOG4107EEX Cellulose synthase regulator protein HVW55_00995 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HVW55_01000 ENOG4105EJG cellulose synthase HVW55_01005 ENOG4105BZU Histidine kinase HVW55_01015 ENOG4105CS0 peptidase HVW55_01025 ENOG4105CMB EAL domain-containing protein HVW55_01030 ENOG41066T0 asmA family HVW55_01035 ENOG4105CSH Transporter HVW55_01040 ENOG4107H3J ribonuclease HVW55_01045 ENOG4105CBN LysR family transcriptional regulator HVW55_01050 ENOG4106S2D Transcriptional regulator HVW55_01060 ENOG4105CA0 peroxidase HVW55_01065 ENOG4105CVK Glutamate decarboxylase HVW55_01070 ENOG4108NKV transcriptional regulator HVW55_01080 ENOG4105BZS acriflavin resistance protein HVW55_01085 ENOG4105C1P efflux transporter, rnd family, mfp subunit HVW55_01095 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HVW55_01100 ENOG4108YK4 Acid-resistance membrane protein HVW55_01105 ENOG41060V2 Acid-resistance protein HVW55_01110 ENOG4105XXV Acid-resistance protein HVW55_01115 ENOG4105KT7 mgtC SapB transporter HVW55_01125 ENOG4105EHG Permease protein HVW55_01135 ENOG41090JE Utilization Protein HVW55_01140 ENOG4105D4P Coproporphyrinogen iii oxidase HVW55_01145 ENOG4107R4I Periplasmic binding protein HVW55_01155 ENOG4107ENK receptor HVW55_01160 ENOG4106QJH hemin transport protein HVW55_01170 ENOG4105Y4Z Outer Membrane Lipoprotein HVW55_01180 ENOG4105K89 arsenate reductase HVW55_01195 ENOG4105DC8 reductase HVW55_01200 ENOG4105D6S protein involved in catabolism of external DNA HVW55_01205 ENOG4105DGW oligopeptidase A HVW55_01215 ENOG4105DUX Transporter HVW55_01230 ENOG4105CJ3 phosphate transporter HVW55_01235 ENOG4105CBX hi0933 family HVW55_01240 ENOG4107UNS conserved inner membrane protein HVW55_01255 ENOG4105D0S secretion protein (HlyD HVW55_01260 ENOG4105CJ1 ABC, transporter HVW55_01265 ENOG4105CMI transporter HVW55_01280 ENOG4105D2N Aldolase HVW55_01295 ENOG4105DT3 PTS system, galactitol-specific IIc component HVW55_01300 ENOG41090UW PTS System HVW55_01325 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HVW55_01330 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HVW55_01335 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HVW55_01340 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HVW55_01345 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HVW55_01350 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HVW55_01355 ENOG4105C2D reductase HVW55_01365 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HVW55_01390 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) HVW55_01420 ENOG4105E9Q Acyl-transferase HVW55_01440 ENOG4105DSF transport protein HVW55_01445 ENOG4105F9N Major Facilitator Superfamily HVW55_01450 ENOG4108W1V Lipoprotein HVW55_01455 ENOG4105EX9 Membrane HVW55_01475 ENOG4107FS9 Membrane HVW55_01485 ENOG4105MG3 Membrane HVW55_01490 ENOG4106H78 methyltransferase HVW55_01495 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HVW55_01500 ENOG4105CAK Cell division ATP-binding protein ftsE HVW55_01505 ENOG4105CRP Part of the ABC transporter FtsEX involved in HVW55_01510 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HVW55_01515 ENOG4105CP9 extracellular ligand-binding receptor HVW55_01530 ENOG4105U59 -acetyltransferase HVW55_01535 ENOG4105CP9 extracellular ligand-binding receptor HVW55_01540 ENOG4105C32 Amino acid ABC transporter (Permease) HVW55_01545 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HVW55_01550 ENOG4105C0Z ABC transporter HVW55_01555 ENOG4108IV0 ABC, transporter HVW55_01565 ENOG4105BZ7 extracellular solute-binding protein family 1 HVW55_01570 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HVW55_01575 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HVW55_01580 ENOG4108IJ9 (ABC) transporter HVW55_01585 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HVW55_01590 ENOG4105WC8 Conserved Protein HVW55_01595 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HVW55_01600 ENOG4106FA4 HVW55_01615 ENOG4105GMB type VI secretion system effector, hcp1 family HVW55_01620 ENOG4105WCN acetyltransferase HVW55_01625 ENOG4105D9R oxidoreductase HVW55_01630 ENOG4105C2I pirin domain protein HVW55_01635 ENOG4105DIQ Transcriptional regulator HVW55_01640 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HVW55_01645 ENOG4105C6Z Gluconate HVW55_01650 ENOG4105C9U ATP-dependent DNA helicase RecQ HVW55_01660 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HVW55_01665 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HVW55_01670 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HVW55_01690 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HVW55_01705 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HVW55_01720 ENOG4105E98 transcriptional regulator DeoR family HVW55_01725 ENOG4105CYB regulatoR HVW55_01730 ENOG4105E0Y RtcB Protein HVW55_01755 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HVW55_01760 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HVW55_01765 ENOG4105C6Z Gluconate HVW55_01775 ENOG4105MJ2 Competence protein HVW55_01795 ENOG4105DNE Transposase HVW55_01805 ENOG4105CE1 Ferrous iron transport protein b HVW55_01810 ENOG4105XFK Ferrous iron transport protein A HVW55_01815 ENOG4105BZM domain protein HVW55_01820 ENOG4108RRZ Transcription elongation factor GreB HVW55_01830 ENOG4105E0F Histidine kinase HVW55_01840 ENOG4108MAJ Membrane HVW55_01850 ENOG4105VEJ Heat shock protein HVW55_01855 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HVW55_01860 ENOG4105DQY intracellular growth attenuator HVW55_01865 ENOG4107RK2 ADP-ribose diphosphatase NudE HVW55_01870 ENOG4108JQC penicillin-binding protein 1A HVW55_01875 ENOG4108U1Q Pilus assembly protein HVW55_01880 ENOG41065NF Fimbrial assembly family protein HVW55_01885 ENOG4105XPX DNA utilization protein HofO HVW55_01890 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HVW55_01895 ENOG4105E4G Type IV pilus HVW55_01905 ENOG4105D49 3-dehydroquinate synthase HVW55_01910 ENOG4105EGB membrane protein DamX HVW55_01915 ENOG4105DFE Dna adenine methylase HVW55_01920 ENOG4105DJV ribulose-phosphate 3-epimerase HVW55_01925 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HVW55_01930 ENOG4105C31 Tryptophanyl-tRNA synthetase HVW55_01935 ENOG4108M21 HVW55_01940 ENOG4105RMW regulation of transcription, DNA-dependent HVW55_01945 ENOG4108626 Racemase HVW55_01950 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HVW55_01955 ENOG41080QX K07048 phosphotriesterase-related protein HVW55_01960 ENOG4105MUZ Protein of unknown function DUF2620 HVW55_01965 ENOG4106M0N transport system permease protein HVW55_01970 ENOG4106PKC pyridoxal phosphate binding HVW55_01975 ENOG4105VYH HVW55_01985 ENOG4107V9H nitrite transporter HVW55_01990 ENOG4105WZK nitrite reductase NADPH small subunit HVW55_01995 ENOG4107QZF nitrite reductase NADPH large subunit HVW55_02005 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HVW55_02015 ENOG4105MZU cell filamentation protein HVW55_02020 ENOG4105DDQ anthranilate synthase HVW55_02025 ENOG4105C8Y Acetylornithine aminotransferase HVW55_02030 ENOG410613R integral membrane protein, YccS YhfK family HVW55_02040 ENOG4108UKZ OsmC family HVW55_02045 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HVW55_02055 ENOG4105DNZ Alpha Beta Hydrolase HVW55_02060 ENOG4105C5H ABC transporter HVW55_02075 ENOG4105VKU nucleicacid-binding protein HVW55_02080 ENOG4108YZY peptidylprolyl cis-trans isomerase HVW55_02090 ENOG4108V1T peptidylprolyl cis-trans isomerase HVW55_02095 ENOG4105WWK YheO domain protein HVW55_02100 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) HVW55_02105 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) HVW55_02135 ENOG4105W53 bacterioferritin-associated ferredoxin HVW55_02140 ENOG4108UQY Iron-storage protein HVW55_02165 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HVW55_02210 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HVW55_02255 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HVW55_02260 ENOG41067V7 50S ribosomal protein L36 HVW55_02290 ENOG4105VTS DnaJ-like, subfamily C HVW55_02295 ENOG4105W1Y Transcriptional regulator HVW55_02300 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HVW55_02310 ENOG4105C1A potassium transporter peripheral membrane HVW55_02330 ENOG4105C79 DNA protecting protein DprA HVW55_02340 ENOG4108WI1 Dna topoisomerase HVW55_02355 ENOG4105SG3 Protein of unknown function (DUF1488) HVW55_02360 ENOG4108Z0R Transferase HVW55_02400 ENOG4105CDA abc transporter atp-binding protein HVW55_02405 ENOG4105DRP amino acid AbC transporter HVW55_02410 ENOG4105EZ7 amino acid ABC transporter HVW55_02420 ENOG4105XCM membrane LIPOPROTEIN HVW55_02425 ENOG4105BZS acriflavin resistance protein HVW55_02430 ENOG4105C1P efflux transporter, rnd family, mfp subunit HVW55_02435 ENOG4108XG4 DNA-binding transcriptional regulator HVW55_02440 ENOG41061ME transport protein HVW55_02445 ENOG4105CEC DNA methylase N-4 N-6 HVW55_02455 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HVW55_02465 ENOG4108IA2 Sodium pantothenate symporter HVW55_02470 ENOG4105RG0 Membrane HVW55_02475 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HVW55_02480 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HVW55_02490 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HVW55_02495 ENOG41062P1 Diguanylate cyclase phosphodiesterase HVW55_02505 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HVW55_02510 ENOG4105VQ7 Rod shape-determining protein MreD HVW55_02520 ENOG4105C03 ribonuclease HVW55_02525 ENOG4105QD6 exported protein HVW55_02530 ENOG4105D1U peptidase U62 modulator of DNA gyrase HVW55_02535 ENOG4105CR8 Transcriptional regulator HVW55_02540 ENOG4105ZQC membrane protein AaeX HVW55_02555 ENOG4105UNR (Barnase) inhibitor HVW55_02560 ENOG4105RID UPF0379 protein yhcN HVW55_02575 ENOG4105C0H protease HVW55_02580 ENOG4105C0H protease HVW55_02585 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HVW55_02590 ENOG4105D6Z AFG1 family ATPase HVW55_02605 ENOG4107MKT Stringent starvation protein a HVW55_02610 ENOG4105KB2 stringent starvation protein b HVW55_02615 ENOG4105CEE C4-dicarboxylate transporter HVW55_02620 ENOG4108QBF Transcriptional regulator HVW55_02630 ENOG4105JHE Major Facilitator Superfamily HVW55_02645 ENOG4108R66 Conserved Protein HVW55_02650 ENOG4105DFS Conserved Protein HVW55_02655 ENOG4105BZ8 glutamate synthase HVW55_02660 ENOG4105CBC glutamate synthase HVW55_02665 ENOG4105N5T Radical SAM Protein HVW55_02670 ENOG4105BZU Histidine kinase HVW55_02675 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HVW55_02685 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HVW55_02690 ENOG41080Z8 PHOSPHOCARRIER protein HVW55_02700 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HVW55_02705 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HVW55_02710 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HVW55_02715 ENOG4108IUZ ABC transporter HVW55_02720 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HVW55_02725 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HVW55_02730 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase HVW55_02735 ENOG4105C2X Arabinose 5-phosphate isomerase HVW55_02740 ENOG4105FEU K -dependent Na -Ca exchanger HVW55_02745 ENOG4105DHJ ABC, transporter HVW55_02750 ENOG4105CY3 ABC transporter, permease HVW55_02755 ENOG4107PE3 Mammalian cell entry related domain protein HVW55_02760 ENOG4105E3I toluene tolerance HVW55_02765 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HVW55_02770 ENOG4105VFK BolA family HVW55_02780 ENOG4105HVQ Regulatory factor of maltose metabolism HVW55_02785 ENOG4105EAH synthase HVW55_02800 ENOG4105QYV Membrane HVW55_02810 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HVW55_02815 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HVW55_02820 ENOG4105HBR Rna-binding protein HVW55_02830 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HVW55_02835 ENOG4105EEI dihydropteroate synthase HVW55_02845 ENOG4105NTZ Preprotein translocase subunit SecG HVW55_02855 ENOG4105DIJ Phosphoethanolamine transferase HVW55_02875 ENOG4105CHV Transcription elongation factor NusA HVW55_02915 ENOG4105C1J atp-dependent rna helicase HVW55_02920 ENOG4105CIC tryptophan-specific transport protein HVW55_02925 ENOG4105DEN Luciferase family HVW55_02945 ENOG4108YYD acetyltransferase HVW55_02960 ENOG4107R7Y intracellular protease Pfpi family HVW55_02965 ENOG4105K4T epimerase HVW55_02970 ENOG4107S21 permease HVW55_02975 ENOG4105W4M Transport-associated protein HVW55_02995 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HVW55_03015 ENOG4105C87 Aminotransferase class I and II HVW55_03020 ENOG4105CI1 PTS System HVW55_03030 ENOG4105E70 isomerase HVW55_03035 ENOG4105CE4 GlcNAc 6-P deacetylase HVW55_03040 ENOG4108YTN IIa component HVW55_03055 ENOG4105HVQ Regulatory factor of maltose metabolism HVW55_03060 ENOG4106YXT transposase HVW55_03065 ENOG4108WTW DNA transposition protein HVW55_03090 ENOG4105IKI host-nuclease inhibitor protein HVW55_03170 ENOG4108Z6H mu-like prophage Flumu protein gp27 HVW55_03175 ENOG4105CF2 Mu-like prophage FluMu protein GP28 HVW55_03180 ENOG4105QIB mu-like prophage Flumu protein gp29 HVW55_03185 ENOG4108QUU Morphogenesis Protein HVW55_03190 ENOG4107XYH virion morphogenesis protein HVW55_03195 ENOG4108TVE i protein HVW55_03200 ENOG4105EFV Major head subunit HVW55_03225 ENOG4105TKZ Tail Sheath HVW55_03235 ENOG41062PQ Mu-like prophage FluMu protein gp41 HVW55_03245 ENOG4108NKR DNA circulation protein HVW55_03255 ENOG4105PZ7 Baseplate assembly protein HVW55_03260 ENOG4105WR6 Phage protein, GP46 HVW55_03265 ENOG4108T86 baseplate J family protein HVW55_03275 ENOG4106IKR HVW55_03280 ENOG4105UZW Tail fiber assembly protein HVW55_03290 ENOG4108C33 Resolvase HVW55_03315 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HVW55_03325 ENOG4105E98 transcriptional regulator DeoR family HVW55_03330 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HVW55_03335 ENOG4105ZEG Suppressor protein HVW55_03340 ENOG4105CTX dehydratase HVW55_03345 ENOG4105DJB Major Facilitator Superfamily HVW55_03355 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HVW55_03360 ENOG4105BZW Glycerate kinase HVW55_03385 ENOG410811B TRANSCRIPTIONal HVW55_03390 ENOG4105C7B Threonine dehydratase HVW55_03395 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) HVW55_03400 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HVW55_03405 ENOG4105C6N Formate acetyltransferase HVW55_03410 ENOG4105KME endoribonuclease L-psp HVW55_03415 ENOG4105EJQ L-serine dehydratase HVW55_03420 ENOG4105C44 Serine transporter HVW55_03430 ENOG4106D80 Uncharacterized protein YhaL HVW55_03435 ENOG4108CNN domain protein HVW55_03440 ENOG4105CWB LysR family transcriptional Regulator HVW55_03445 ENOG4105KAF membrAne HVW55_03450 ENOG4105KAF membrAne HVW55_03455 ENOG4105CHF Glutathione S-transferase HVW55_03460 ENOG4108VBZ doxx family HVW55_03465 ENOG4105YJD HVW55_03470 ENOG41090KG Inner membrane protein YqjE HVW55_03475 ENOG4105NE1 Conserved Protein HVW55_03480 ENOG4105WAY exported protein HVW55_03485 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HVW55_03490 ENOG4106W5V Membrane HVW55_03495 ENOG4107YCY Transcriptional regulator HVW55_03500 ENOG4105DPW Major facilitator superfamily MFS_1 HVW55_03510 ENOG4105CTX dehydratase HVW55_03515 ENOG4105P66 Membrane HVW55_03520 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HVW55_03525 ENOG4105DU1 integral membrane protein, terc HVW55_03530 ENOG4105EE0 oxidoreductase HVW55_03535 ENOG4108UB4 uncharacterized protein ygjQ HVW55_03540 ENOG4108VKG metal-dependent hydrolase HVW55_03550 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase HVW55_03555 ENOG4108Z3N Transcriptional regulator HVW55_03560 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HVW55_03565 ENOG4107WCA isomerase HVW55_03570 ENOG4107W6W Conserved Protein HVW55_03575 ENOG4105E5D amino acid HVW55_03580 ENOG4105FK9 beta-D-galactosidase beta subunit HVW55_03585 ENOG4105CNT hydrolase family 2 HVW55_03590 ENOG4105CQ4 Transcriptional regulator HVW55_03595 ENOG4108Y51 tRNA-binding protein HVW55_03605 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HVW55_03610 ENOG4105NTW Transcriptional regulator HVW55_03615 ENOG4105Q26 Siderophore-interacting protein HVW55_03630 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HVW55_03635 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HVW55_03650 ENOG4107QPK )-transporter HVW55_03655 ENOG4107GFK fumarate HVW55_03665 ENOG4105EJC lysr family transcriptional regulator HVW55_03675 ENOG4107ZVW dihydroneopterin aldolase HVW55_03690 ENOG4106MWK domain protein HVW55_03695 ENOG4105I7R Adenylate cyclase HVW55_03725 ENOG4105PV3 Inner membrane protein yqiJ HVW55_03735 ENOG4105W0Z cytoplasmic protein HVW55_03755 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HVW55_03760 ENOG4106032 Glutathionylspermidine synthase HVW55_03770 ENOG4105DFG type I secretion outer membrane protein HVW55_03775 ENOG41087AY ADP-Ribose pyrophosphatase HVW55_03780 ENOG4108SX3 cytoplasmic protein HVW55_03785 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HVW55_03790 ENOG4105IPS esterase HVW55_03795 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HVW55_03805 ENOG4105E0A ABC, transporter HVW55_03810 ENOG4105DQ5 transport system permease protein HVW55_03815 ENOG4105EHG Permease protein HVW55_03825 ENOG4106KNT transcriptional regulator HVW55_03830 ENOG4105VRH Antibiotic biosynthesis monooxygenase HVW55_03835 ENOG4105NF4 modulator of drug activity HVW55_03840 ENOG4105DHQ Histidine kinase HVW55_03845 ENOG4105XJC Two component transcriptional regulator (Winged helix family HVW55_03850 ENOG4105H4F exported protein HVW55_03855 ENOG4105F4I Transcriptional regulator HVW55_03860 ENOG4108J59 Extracellular solute-binding protein, family 5 HVW55_03865 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HVW55_03870 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HVW55_03875 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HVW55_03880 ENOG4105CCT upf0313 protein HVW55_03890 ENOG4105ZKC Conserved Protein HVW55_03895 ENOG4105CV8 reductase HVW55_03900 ENOG4108I6A alcohol dehydrogenase HVW55_03905 ENOG4105CF7 AraC family transcriptional regulator HVW55_03910 ENOG4108K81 inner membrane protein YghB HVW55_03915 ENOG4105C28 cystathionine HVW55_03920 ENOG4105CWK Biopolymer transport protein, ExbB HVW55_03925 ENOG4108ZZF transport protein (ExbD) HVW55_03930 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HVW55_03940 ENOG4105CPC Aldo Keto reductase HVW55_03950 ENOG410900S Protein of unknown function (DUF2623) HVW55_03955 ENOG4105E3S small subunit HVW55_03960 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HVW55_03965 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HVW55_03970 ENOG4105DPX Hydrogenase, large subunit HVW55_03975 ENOG4108USZ hydrogenase HVW55_03980 ENOG4108WGS hydrogenase 2-specific chaperone HVW55_03990 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HVW55_03995 ENOG4105CYM Glutathione S-transferase HVW55_04000 ENOG4106032 Glutathionylspermidine synthase HVW55_04005 ENOG4105CJ3 phosphate transporter HVW55_04010 ENOG4108GH0 ATP-binding protein yghT HVW55_04015 ENOG4108NDC ATP-binding protein yghS HVW55_04020 ENOG4106FPV ATP-binding protein YghR HVW55_04025 ENOG4108S55 polysaccharide biosynthesis protein HVW55_04035 ENOG4108UUE Transcriptional regulator HVW55_04040 ENOG4108M8S permease YjgP YjgQ family protein HVW55_04050 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HVW55_04055 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HVW55_04065 ENOG4107RCI amp-dependent synthetase and ligase HVW55_04075 ENOG4108KWP DNA-binding transcriptional regulator GlcC HVW55_04080 ENOG4105CQB FAD linked oxidase domain protein HVW55_04085 ENOG4105EU8 FAD linked oxidase domain protein HVW55_04090 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HVW55_04095 ENOG4108ZJF Glcg protein HVW55_04100 ENOG4107QP3 malate synthase g HVW55_04105 ENOG4105DAA L-lactate HVW55_04120 ENOG410765S (LipO)protein HVW55_04135 ENOG4107QHF type ii secretion system protein e HVW55_04140 ENOG4105D7Q type ii secretion system HVW55_04145 ENOG4108VAU general secretion pathway protein G HVW55_04155 ENOG4105X5Z General secretion pathway protein I HVW55_04175 ENOG4105U1E general secretion pathway protein M HVW55_04200 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HVW55_04210 ENOG4108YGG dna repair protein HVW55_04215 ENOG4105MFG Antirestriction protein HVW55_04225 ENOG4106H6R UPF0380 protein HVW55_04240 ENOG4108PZQ Inner membrane protein YeeR HVW55_04245 ENOG4105F4K antigen 43 HVW55_04330 ENOG4105DNE Transposase HVW55_04345 ENOG4105D5K Hemolysin activator protein HVW55_04350 ENOG4105CKT filamentous hemagglutinin HVW55_04375 ENOG4106QAN HVW55_04395 ENOG4105E5H Transposase HVW55_04400 ENOG4108YXQ IS66 Orf2 family protein HVW55_04410 ENOG4105EKQ RNA-directed DNA polymerase HVW55_04425 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) HVW55_04430 ENOG4105CSX c4-dicarboxylate anaerobic carrier HVW55_04435 ENOG4105DBV ornithine carbamoyltransferase HVW55_04440 ENOG4105C5B carbamate kinase HVW55_04445 ENOG4105CEU Arginine dihydrolase HVW55_04480 ENOG4107SCJ type I restriction enzyme EcoKI subunit R HVW55_04490 ENOG41082EK Restriction modification system DNA (Specificity HVW55_04495 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HVW55_04520 ENOG4105EQR Transposase IS116 IS110 IS902 HVW55_04525 ENOG4105BZU Histidine kinase HVW55_04535 ENOG4105Z68 AraC Family Transcriptional Regulator HVW55_04540 ENOG4105DFP Integrase HVW55_04575 ENOG4105CDU Replicative dna helicase HVW55_04620 ENOG4105GNX MltA-interacting MipA family protein HVW55_04630 ENOG4108IYH Dna topoisomerase HVW55_04645 ENOG4108UUM single-stranded DNA-binding protein HVW55_04650 ENOG4105DNE Transposase HVW55_04780 ENOG4108YXQ IS66 Orf2 family protein HVW55_04785 ENOG4105E5H Transposase HVW55_04910 ENOG4105DVP Adenine-specific HVW55_04925 ENOG41088T4 Helicase IV HVW55_04945 ENOG4108UQV Membrane HVW55_04950 ENOG4105CXN decarboxylase HVW55_04955 ENOG4105EAA nucleoside HVW55_04970 ENOG4105CEN a g-specific adenine glycosylase HVW55_04980 ENOG41090ED Protein with unknown function (DUF469) HVW55_04990 ENOG4105K33 Periplasmic Protein HVW55_04995 ENOG4105HDK L-asparaginase HVW55_05000 ENOG4106MH3 alpha helix chain HVW55_05005 ENOG4105CSA Coproporphyrinogen iii oxidase HVW55_05010 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HVW55_05020 ENOG4108VIA integral membrane protein HVW55_05025 ENOG4105DFA alanine racemase domain protein HVW55_05030 ENOG4105CZX twitching motility protein HVW55_05045 ENOG4105D7Z glutathione synthase HVW55_05050 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HVW55_05055 ENOG4105RWS endonuclease I HVW55_05065 ENOG4107QNK )-transporter HVW55_05085 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HVW55_05100 ENOG4108K0D peptidase, M48 HVW55_05105 ENOG4105CV1 Transketolase (EC 2.2.1.1) HVW55_05110 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HVW55_05115 ENOG4105CTS PTS system mannitol-specific HVW55_05120 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HVW55_05125 ENOG4108Q8A Fructose-1,6-bisphosphatase HVW55_05130 ENOG4108R4K DNA-binding, transcriptional regulator HVW55_05135 ENOG4107Z1W Fructose transport system kinase HVW55_05140 ENOG4108JJB ABC transporter HVW55_05145 ENOG4108JJB ABC transporter HVW55_05175 ENOG4105D2N Aldolase HVW55_05180 ENOG4105D64 Mechanosensitive ion channel HVW55_05195 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HVW55_05200 ENOG4105MPN Membrane HVW55_05205 ENOG4105DEQ transcriptional regulator HVW55_05210 ENOG4105CYC Transferase HVW55_05215 ENOG4108M7F enoyl-CoA hydratase isomerase HVW55_05220 ENOG4105DJT lAO AO transport system ATPase HVW55_05225 ENOG4105D5P Methylmalonyl-coA mutase HVW55_05235 ENOG4105E3J oxidoreductase HVW55_05240 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HVW55_05245 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) HVW55_05260 ENOG4108JQ1 Dehydrogenase HVW55_05270 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HVW55_05290 ENOG4107RAQ aminopeptidase HVW55_05295 ENOG4105D0A hydroxylase HVW55_05300 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HVW55_05325 ENOG4105CS2 ec 3.2.1.21 HVW55_05330 ENOG4105N5Z UPF0267 protein HVW55_05335 ENOG4108UT2 hemolysin iii HVW55_05345 ENOG4105Y75 tpr repeat protein HVW55_05350 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HVW55_05355 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HVW55_05360 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HVW55_05365 ENOG4105T95 Thiol disulfide interChange protein HVW55_05370 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HVW55_05380 ENOG4105CRK lysyL-tRNA synthetase HVW55_05400 ENOG4105C2W permease HVW55_05405 ENOG4105BZ8 glutamate synthase HVW55_05410 ENOG4108R8B oxidoreductase Fe-S subunit HVW55_05415 ENOG4105C7N Xanthine uracil vitamin C permease HVW55_05420 ENOG4107QUY Guanine deaminase HVW55_05425 ENOG4105C2W permease HVW55_05430 ENOG4105C7W Xanthine dehydrogenase HVW55_05435 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HVW55_05440 ENOG4107UUR Chlorohydrolase aminohydrolase HVW55_05445 ENOG4105BZ8 glutamate synthase HVW55_05450 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HVW55_05455 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HVW55_05460 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HVW55_05465 ENOG4105C5B carbamate kinase HVW55_05475 ENOG4107S4Y M20 DapE family protein YgeY HVW55_05480 ENOG4107RCH Diaminopropionate ammonia-lyase HVW55_05485 ENOG4105IW6 Carbamoyltransferase HVW55_05490 ENOG4108JUB Transcriptional regulator HVW55_05495 ENOG4108UTP (2Fe-2S)-binding domain protein HVW55_05500 ENOG4108HR6 Dehydrogenase HVW55_05505 ENOG4105C7W Xanthine dehydrogenase HVW55_05510 ENOG4108K5P (LipO)protein HVW55_05520 ENOG4108T88 HVW55_05530 ENOG41090HZ type iii secretion HVW55_05540 ENOG4108N8R Invasion protein HVW55_05545 ENOG4108HR8 type iii secretion HVW55_05550 ENOG4108JIR Flagellum-specific ATP synthase HVW55_05565 ENOG4105T85 surface presentation of antigens protein HVW55_05570 ENOG41075IY surface presentation of antigens protein SpaP HVW55_05575 ENOG4105U07 type iii secretion HVW55_05590 ENOG4108YAB Invasion protein HVW55_05615 ENOG4105FV3 HVW55_05620 ENOG4108TC1 Transcriptional regulator HVW55_05625 ENOG4105ISV protein with bipartite regulator domain HVW55_05630 ENOG4108MHD transport protein HVW55_05635 ENOG4105CHU acetyl-coa acetyltransferase HVW55_05645 ENOG4105CHR reductase HVW55_05650 ENOG4107QNK )-transporter HVW55_05660 ENOG4105RQF LysR family Transcriptional regulator HVW55_05670 ENOG41060NJ transcriptional regulator HVW55_05685 ENOG4105CPC Aldo Keto reductase HVW55_05690 ENOG4105SUV lipoprotein YgdR HVW55_05695 ENOG4105EE5 Membrane protein terC HVW55_05710 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HVW55_05725 ENOG4105IPU prepilin peptidase dependent protein A HVW55_05730 ENOG4105JCS prepilin peptidase dependent protein HVW55_05735 ENOG4105SEN Protein of unknown function (DUF2509) HVW55_05740 ENOG4105RVB Prepilin peptidase dependent protein c HVW55_05745 ENOG4105DSY exodeoxyribonuclease V, gamma HVW55_05750 ENOG4107QXK peptidase HVW55_05755 ENOG4107QKA exodeoxyribonuclease V beta HVW55_05760 ENOG4107QYX exodeoxyribonuclease v alpha HVW55_05765 ENOG4108EKC n-acetylglutamate synthase HVW55_05770 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HVW55_05790 ENOG4105CA3 membrane-bound lytic murein transglycosylase HVW55_05795 ENOG4105CUZ uba thif-type nad fad binding protein HVW55_05800 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HVW55_05805 ENOG4105C9B Cysteine desulfurase HVW55_05810 ENOG4105M5B (LipO)protein HVW55_05815 ENOG4105ETT transcriptional Regulator, LysR family HVW55_05820 ENOG4105M08 Membrane HVW55_05830 ENOG4107EDW L-fucose operon activator HVW55_05840 ENOG4105CMG Carbohydrate kinase HVW55_05845 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) HVW55_05850 ENOG4105EDR glucose galactose transporter HVW55_05855 ENOG4107W7X Aldolase HVW55_05860 ENOG4105C0A alcohol dehydrogenase HVW55_05870 ENOG4105EJQ L-serine dehydratase HVW55_05875 ENOG4105C44 Serine transporter HVW55_05880 ENOG4105EWT decarboxylase family HVW55_05895 ENOG4105WP7 tRNA pseudouridine synthase C HVW55_05900 ENOG4105DR9 pseudouridine synthase HVW55_05905 ENOG4105QDK Flavodoxin HVW55_05910 ENOG4105DJB Major Facilitator Superfamily HVW55_05915 ENOG4105EQX glucarate dehydratase HVW55_05920 ENOG4105EQX glucarate dehydratase HVW55_05925 ENOG4105BZU Histidine kinase HVW55_05935 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HVW55_05940 ENOG4106A2Z transcriptional regulator antitoxin, MazE HVW55_05945 ENOG4105MZG transcriptional modulator of maze toxin, mazf HVW55_05950 ENOG4105DXN mazG family HVW55_05965 ENOG4105VNT transposase (IS4 family) protein HVW55_05980 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HVW55_05985 ENOG4108CWB sugar kinase ygcE HVW55_05990 ENOG4108ITV Inner membrane protein yqcE HVW55_05995 ENOG4105CHR reductase HVW55_06000 ENOG4107R3A FAD linked oxidase domain protein HVW55_06005 ENOG4105C54 Major Facilitator superfamily HVW55_06010 ENOG4106IKH Electron transfer flavoprotein HVW55_06015 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HVW55_06020 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HVW55_06025 ENOG4105WQV ferredoxin-like protein HVW55_06030 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HVW55_06035 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HVW55_06055 ENOG4105DTT CRISPR-associated helicase, cas3 HVW55_06060 ENOG4105CYR Crispr-associated protein, cse1 family HVW55_06065 ENOG41061HK CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) HVW55_06070 ENOG41060M0 Crispr-associated protein, cse4 family HVW55_06075 ENOG4108VWQ crispr-associated protein HVW55_06080 ENOG4108Y7V CRISPR-associated protein, Cse3 family HVW55_06085 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HVW55_06090 ENOG4105PWE CRISPR-associated protein cas2 HVW55_06095 ENOG4108MXK alkaline phosphatase isozyme conversion HVW55_06115 ENOG4105N0Z inner membrane protein ygbE HVW55_06150 ENOG4108K5P (LipO)protein HVW55_06155 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HVW55_06165 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HVW55_06170 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HVW55_06175 ENOG4105KZM cytoplasmic protein HVW55_06180 ENOG4105MEW serine threonine protein phosphatase HVW55_06195 ENOG4105VXR cytoplasmic protein HVW55_06200 ENOG4108JUA Transcriptional regulator HVW55_06205 ENOG4105C45 hydrogenase expression formation protein (HypE) HVW55_06210 ENOG4105CQS hydrogenase expression formation protein HypD HVW55_06215 ENOG41083WG hydrogenase assembly chaperone HVW55_06220 ENOG4107RSS Hydrogenase accessory protein HypB HVW55_06225 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HVW55_06230 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HVW55_06235 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HVW55_06240 ENOG4107R30 NADH dehydrogenase HVW55_06245 ENOG4107TDF Formate hydrogenlyase subunit 4 HVW55_06250 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HVW55_06255 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HVW55_06260 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HVW55_06265 ENOG4105I6X formate hydrogenlyase maturation HVW55_06270 ENOG4108MG9 hydrogenase 3 maturation protease HVW55_06285 ENOG4105CS2 ec 3.2.1.21 HVW55_06290 ENOG4105C5Y PTS System HVW55_06295 ENOG4105DDV Transcriptional regulator (LacI family HVW55_06300 ENOG4108RC0 Electron transport protein HVW55_06305 ENOG4105C8H hydrogenase maturation protein Hypf HVW55_06325 ENOG4105C2X Arabinose 5-phosphate isomerase HVW55_06330 ENOG410804X Transcriptional regulator HVW55_06335 ENOG4105J92 DNA-binding transcriptional activator GutM HVW55_06340 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HVW55_06345 ENOG4105VI0 Pts system, glucitol sorbitol-specific HVW55_06350 ENOG4105DZY Pts system, glucitol sorbitol-specific HVW55_06355 ENOG410787A Pts system, glucitol sorbitol-specific HVW55_06360 ENOG4105CVE Lytic murein transglycosylase HVW55_06365 ENOG4107TH8 cina domain protein HVW55_06385 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HVW55_06415 ENOG4107VXZ Hydrolase HVW55_06420 ENOG4105W39 Membrane HVW55_06445 ENOG4105C0R drug resistance transporter emrb qaca subfamily HVW55_06450 ENOG4105CW7 secretion protein, HlyD family HVW55_06455 ENOG4105NTK Transcriptional repressor Mpra HVW55_06460 ENOG4105ZED uncharacterized protein ygaH HVW55_06465 ENOG4108UMN azlc family HVW55_06470 ENOG4105EQ0 Major Facilitator superfamily HVW55_06475 ENOG4105GIJ Glycine betaine HVW55_06480 ENOG4108HQS Glycine betaine HVW55_06485 ENOG4108IJ7 Glycine betaine HVW55_06490 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HVW55_06495 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HVW55_06505 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HVW55_06510 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HVW55_06520 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HVW55_06525 ENOG4108WMJ Protein of unknown function (DUF2002) HVW55_06530 ENOG4108RNS Exports L-alanine (By similarity) HVW55_06535 ENOG4108X73 DNA- binding protein HVW55_06540 ENOG4108V62 Rhodanese domain protein HVW55_06545 ENOG41080HT Transcriptional regulator, arsr family HVW55_06550 ENOG4105VPI YqaE family transport protein HVW55_06555 ENOG4109066 lysm domain bon superfamily protein HVW55_06560 ENOG4108PVQ transcriptional regulator HVW55_06565 ENOG4105C85 amino acid HVW55_06570 ENOG4108JPW Aminotransferase HVW55_06575 ENOG4105C26 Dehydrogenase HVW55_06580 ENOG4105D5U fad dependent oxidoreductase HVW55_06590 ENOG4105E54 alpha-amylase HVW55_06675 ENOG4105DFP Integrase HVW55_06690 ENOG4108Z1B Cyclase dehydrase HVW55_06700 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HVW55_06705 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HVW55_06720 ENOG4108JU6 CBS domain protein HVW55_06725 ENOG4106KVJ cytochrome C assembly protein HVW55_06730 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HVW55_06755 ENOG41090EK ompa motb domain protein HVW55_06765 ENOG4108WS1 HVW55_06770 ENOG4105QP9 Protein of unknown function (DUF2799) HVW55_06775 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HVW55_06780 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HVW55_06785 ENOG4105CQC Prephenate dehydratase HVW55_06795 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HVW55_06800 ENOG4105VNT transposase (IS4 family) protein HVW55_06805 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HVW55_06810 ENOG4105C34 Pseudouridine synthase HVW55_06815 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HVW55_06820 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HVW55_06845 ENOG4105CSH Transporter HVW55_06850 ENOG4105T42 (LipO)protein HVW55_06855 ENOG4105JIM Phosphatidylserine synthase HVW55_06860 ENOG4105CD5 CoA-binding domain protein HVW55_06865 ENOG4106IUH DTW domain containing protein HVW55_06870 ENOG4105K63 Thioredoxin HVW55_06875 ENOG4105EIB trna rrna methyltransferase HVW55_06890 ENOG4108VP3 Lysine exporter protein (LysE YggA) HVW55_06895 ENOG41090KR LysR family transcriptional Regulator HVW55_06900 ENOG4105C1J atp-dependent rna helicase HVW55_06910 ENOG4108IYU L-aspartate oxidase HVW55_06920 ENOG4105EMN RNA polymerase sigma factor HVW55_06925 ENOG41069PW sigma-e factor negative regulatory protein HVW55_06930 ENOG4105VQK sigma E regulatory protein, MucB RseB HVW55_06935 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HVW55_06945 ENOG4105C3F Signal peptidase i HVW55_06965 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HVW55_06980 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HVW55_06985 ENOG4106G6Q Transcriptional regulator HVW55_06990 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HVW55_06995 ENOG4108Z6B deaminase HVW55_07005 ENOG4108ETH Formylglycinamide ribotide synthetase HVW55_07010 ENOG4107WP9 Histidine kinase HVW55_07015 ENOG4108SKK alpha helix protein HVW55_07020 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HVW55_07030 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HVW55_07040 ENOG4108NZE NAGC-like transcriptional regulator HVW55_07045 ENOG4107HQ7 repeat protein HVW55_07050 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HVW55_07055 ENOG4108F37 ATP-binding component of a transport system HVW55_07060 ENOG4105CNN ABC, transporter HVW55_07065 ENOG4105CPQ Dehydrogenase HVW55_07070 ENOG4108ZKT aldose 1-epimerase HVW55_07075 ENOG4108SB3 DoxX Family HVW55_07100 ENOG4105FUY alpha subunit HVW55_07105 ENOG4108W5M transcriptional regulator HVW55_07110 ENOG4105D8G Major Facilitator superfamily HVW55_07115 ENOG4108MN2 Stationary phase inducible protein CsiE HVW55_07120 ENOG4107XM9 (LipO)protein HVW55_07125 ENOG4105ECY inositol monophosphatase HVW55_07145 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HVW55_07165 ENOG4108ZIT Ferredoxin, 2FE-2S HVW55_07170 ENOG4105WVQ Fe-S assembly protein IscX HVW55_07180 ENOG4105YYA enhanced serine sensitivity protein SseB HVW55_07190 ENOG4105KHC sulfurtransferase HVW55_07195 ENOG4105DN3 alpha-2-macroglobulin domain protein HVW55_07200 ENOG4108JQB penicillin-binding protein 1C HVW55_07230 ENOG4105N21 Membrane HVW55_07245 ENOG4105VPD cellular component movement HVW55_07270 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HVW55_07275 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) HVW55_07290 ENOG41066DY Membrane HVW55_07295 ENOG4108ZMA Outer membrane lipoprotein HVW55_07300 ENOG41062G3 Protein of unknown function (DUF2633) HVW55_07310 ENOG4105BZU Histidine kinase HVW55_07315 ENOG4105C9X ppx gppa phosphatase HVW55_07320 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HVW55_07325 ENOG4108V3E phosphoribosylglycinamide formyltransferase HVW55_07340 ENOG4105C2W permease HVW55_07345 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HVW55_07350 ENOG4105K89 arsenate reductase HVW55_07355 ENOG4105ERG peptidase m48, ste24p HVW55_07360 ENOG4105C02 permease HVW55_07365 ENOG4105TMB Formate nitrite transporter HVW55_07370 ENOG4108JUA Transcriptional regulator HVW55_07375 ENOG4105I6X formate hydrogenlyase maturation HVW55_07380 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HVW55_07390 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HVW55_07395 ENOG4108JPZ Monovalent cation H antiporter subunit D HVW55_07400 ENOG4107WQX hydrogenase 4 membrane subunit HVW55_07405 ENOG4105D65 subunit l HVW55_07410 ENOG4107TDF Formate hydrogenlyase subunit 4 HVW55_07415 ENOG4108JPZ Monovalent cation H antiporter subunit D HVW55_07420 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HVW55_07425 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HVW55_07430 ENOG4105RH4 Glycine cleavage system transcriptional repressor HVW55_07440 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HVW55_07455 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HVW55_07460 ENOG4105CGZ zinc metallopeptidase HVW55_07470 ENOG4106KED esterase YpfH HVW55_07485 ENOG4105KUZ arsenate reductase HVW55_07495 ENOG4105BZS acriflavin resistance protein HVW55_07500 ENOG4105BZU Histidine kinase HVW55_07505 ENOG4105BZ8 glutamate synthase HVW55_07515 ENOG4108PVD exported protein HVW55_07520 ENOG4105CV1 Transketolase (EC 2.2.1.1) HVW55_07525 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HVW55_07530 ENOG4105C6K Malic enzyme HVW55_07535 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HVW55_07540 ENOG4106S4J ethanolamine utilization protein EutP HVW55_07545 ENOG4105NDK ethanolamine utilization protein HVW55_07550 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HVW55_07555 ENOG4107WUY phosphate acetyltransferase HVW55_07560 ENOG4105KNY Microcompartments protein HVW55_07565 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HVW55_07570 ENOG4108EKI Dehydrogenase HVW55_07575 ENOG4107RWI ethanolamine utilization protein eutJ HVW55_07580 ENOG4105C0A alcohol dehydrogenase HVW55_07585 ENOG4105ENY Ethanolamine utilization protein eutH HVW55_07590 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HVW55_07595 ENOG4105CPD ethanolamine ammonia-lyase HVW55_07605 ENOG4106D67 ethanolamine utilization protein HVW55_07610 ENOG4108X49 Ethanolamine utilization protein EutK HVW55_07615 ENOG4108K3Z AraC family transcriptional regulator HVW55_07625 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HVW55_07635 ENOG4105QZU Inner membrane protein YfeZ HVW55_07640 ENOG4105E7K (LipO)protein HVW55_07645 ENOG4105EZR dyp-type peroxidase family protein HVW55_07650 ENOG4107S1E Beta-lactamase HVW55_07655 ENOG4105C5Y PTS System HVW55_07670 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HVW55_07675 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HVW55_07680 ENOG4108I5D sulfate abc transporter HVW55_07685 ENOG4105ECW sulfate abc transporter HVW55_07690 ENOG4108IJ6 ABC transporter HVW55_07695 ENOG4105C6T cysteine synthase HVW55_07700 ENOG4105M0Y HVW55_07710 ENOG4105C5Y PTS System HVW55_07715 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HVW55_07725 ENOG4105C6T cysteine synthase HVW55_07745 ENOG4105VRT cytoplasmic protein HVW55_07750 ENOG4105DHU Bile acid HVW55_07755 ENOG4108M0I Transcriptional regulator HVW55_07790 ENOG4105GXM Putative transcription regulator (DUF1323) HVW55_07795 ENOG4105HZG regulatoR HVW55_07810 ENOG4108KMM Diguanylate cyclase HVW55_07815 ENOG4105D9N nucleoside HVW55_07825 ENOG4109076 Conserved Protein HVW55_07830 ENOG4105VCT ion-transport protein YfeO HVW55_07840 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HVW55_07845 ENOG410863U PTS System HVW55_07850 ENOG4105DC7 peptidase M24 HVW55_07855 ENOG4105CN9 Peptidase m42 family protein HVW55_07860 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HVW55_07865 ENOG4108CIP transcriptional regulator HVW55_07870 ENOG4105DY9 regulatoR HVW55_07875 ENOG4108HRK Histidine kinase HVW55_07880 ENOG4105CHM Aminotransferase HVW55_07890 ENOG4105D1S lipid A biosynthesis HVW55_07895 ENOG4105W9M Membrane HVW55_07905 ENOG4108V08 YfdX protein HVW55_07915 ENOG4105CFN oxalyl-CoA decarboxylase HVW55_07920 ENOG4108N2Y auxin Efflux HVW55_07925 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HVW55_07930 ENOG4105BZU Histidine kinase HVW55_07935 ENOG4108WQH regulatoR HVW55_07940 ENOG4105CW7 secretion protein, HlyD family HVW55_07945 ENOG4105C0R drug resistance transporter emrb qaca subfamily HVW55_07960 ENOG4106NDP Transcriptional regulator HVW55_07965 ENOG4108HKT sucrose-6-phosphate hydrolase HVW55_07970 ENOG4105D7K pfkb domain protein HVW55_07975 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HVW55_07990 ENOG4105S64 Formate nitrite transporter HVW55_07995 ENOG410903C (LipO)protein HVW55_08005 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HVW55_08010 ENOG4105KZW UPF0381 protein HVW55_08025 ENOG4108BY2 phosphohistidine phosphatase HVW55_08040 ENOG4108FZ9 Chaperone HVW55_08045 ENOG4105NEV Fimbrial HVW55_08050 ENOG4105UGQ Fimbrial HVW55_08055 ENOG4105US4 fimbrial-like protein yfcP HVW55_08070 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HVW55_08075 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase HVW55_08085 ENOG4105EJ9 Membrane HVW55_08090 ENOG4108BPE -transporting atpase HVW55_08095 ENOG4105MH2 YfcL protein HVW55_08105 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HVW55_08110 ENOG4105F9N Major Facilitator Superfamily HVW55_08115 ENOG4106WZ1 flagella biosynthesis regulator HVW55_08185 ENOG4105UZW Tail fiber assembly protein HVW55_08190 ENOG4108X9F tail fiber protein HVW55_08270 ENOG4105ED4 portal protein HVW55_08360 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HVW55_08370 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HVW55_08380 ENOG4105DQR SNARE associated Golgi HVW55_08390 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HVW55_08395 ENOG4108S3P Sporulation domain protein HVW55_08400 ENOG4105E96 Colicin v production protein HVW55_08405 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HVW55_08410 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HVW55_08415 ENOG4105E89 ABC transporter HVW55_08420 ENOG4105E89 ABC transporter HVW55_08425 ENOG4105DSP amino acid AbC transporter HVW55_08430 ENOG4106YG3 ABC transporter HVW55_08435 ENOG4108JEH abc transporter atp-binding protein HVW55_08440 ENOG4105DNE Transposase HVW55_08445 ENOG4105ECP epimerase HVW55_08450 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HVW55_08455 ENOG4105CYM Glutathione S-transferase HVW55_08460 ENOG4108SHQ Glutathione S-transferase HVW55_08465 ENOG4108RE9 Phosphodiesterase HVW55_08470 ENOG4105PTV Nudix Hydrolase HVW55_08475 ENOG4105CSX c4-dicarboxylate anaerobic carrier HVW55_08480 ENOG4105C6K Malic enzyme HVW55_08485 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HVW55_08495 ENOG4105XWI UPF0304 protein HVW55_08500 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HVW55_08505 ENOG4107QWE )-transporter HVW55_08515 ENOG4105CHM Aminotransferase HVW55_08520 ENOG4107NQ8 LysR family Transcriptional regulator HVW55_08540 ENOG4105GKE subunit e HVW55_08545 ENOG4107QIZ NADH dehydrogenase HVW55_08550 ENOG4108IEH NADH dehydrogenase subunit g HVW55_08565 ENOG4107UFS subunit j HVW55_08575 ENOG4105D65 subunit l HVW55_08580 ENOG4105C8S subunit m HVW55_08590 ENOG4105GDX Domain of unknown function (DUF1877) HVW55_08610 ENOG4107YB6 acetyltransferase, (GNAT) family HVW55_08615 ENOG4105TNS Conserved Protein HVW55_08620 ENOG4105E4F Isochorismate synthase HVW55_08635 ENOG4108IPT Naphthoate synthase HVW55_08640 ENOG4105DNI Converts SHCHC to OSB (By similarity) HVW55_08645 ENOG4105CEY Amp-dependent synthetase and ligase HVW55_08650 ENOG4106GZG polymyxin resistance protein B HVW55_08655 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) HVW55_08700 ENOG4108UII YfaZ family HVW55_08705 ENOG4108EWA cinA-like protein HVW55_08710 ENOG4107258 Transcriptional regulator HVW55_08720 ENOG4105CSP Major Facilitator Superfamily HVW55_08725 ENOG4105CNV Aldolase HVW55_08735 ENOG4105DNE Transposase HVW55_08740 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HVW55_08750 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HVW55_08755 ENOG4105CXY transporter HVW55_08760 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HVW55_08775 ENOG4105FQR PH-inducible protein involved in stress response HVW55_08780 ENOG4105XPH Ferredoxin HVW55_08785 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HVW55_08790 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HVW55_08795 ENOG4107GHC outer membrane autotransporter HVW55_08805 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HVW55_08810 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HVW55_08815 ENOG4108QJJ Protein of unknown function (DUF1175) HVW55_08820 ENOG4107S52 alpha-2-macroglobulin domain protein HVW55_08830 ENOG4105EDV vault protein HVW55_08835 ENOG4105BZU Histidine kinase HVW55_08840 ENOG41068CG regulatoR HVW55_08845 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HVW55_08850 ENOG4105FCK Membrane HVW55_08855 ENOG4105CJ2 (LipO)protein HVW55_08860 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HVW55_08865 ENOG4105CF1 Alkylated DNA repair protein HVW55_08870 ENOG4105IBP Cyclic peptide transporter HVW55_08890 ENOG4108ZNS ferredoxin-type protein NapF HVW55_08895 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HVW55_08905 ENOG4108BGM Quinol dehydrogenase periplasmic component HVW55_08910 ENOG4105GXZ Ferredoxin-type protein NapH HVW55_08915 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HVW55_08920 ENOG4105CUW cytochrome C-TYPE protein HVW55_08925 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HVW55_08930 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HVW55_08935 ENOG41060IM Heme exporter protein HVW55_08940 ENOG4105X3C heme exporter protein HVW55_08950 ENOG4105DA4 cytochrome c-type biogenesis protein HVW55_08955 ENOG4107QX9 Thiol disulfide interChange protein HVW55_08960 ENOG4105KWW Biogenesis protein HVW55_08965 ENOG4105WH1 Two component transcriptional regulator luxr family HVW55_08970 ENOG4108MGN ATP-binding component of a transport system HVW55_08980 ENOG4105E68 Sulfatase HVW55_09000 ENOG4105CFI type iii restriction protein res subunit HVW55_09005 ENOG4105I08 Pseudouridine synthase HVW55_09010 ENOG4105C2C drug resistance transporter, Bcr CflA HVW55_09015 ENOG4105HG6 HVW55_09020 ENOG4108JQ5 ABC transporter HVW55_09025 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HVW55_09030 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HVW55_09035 ENOG4105E43 Extracellular solute-binding protein, family 5 HVW55_09040 ENOG4105CXC rtn protein HVW55_09045 ENOG4107TT5 NLP P60 protein HVW55_09050 ENOG41076MN Phosphoesterase, PA-phosphatase related HVW55_09055 ENOG4105CKI cobalamin synthesis protein HVW55_09060 ENOG4105DEI Mannitol dehydrogenase HVW55_09070 ENOG4105KRS Proteinase inhibitor HVW55_09075 ENOG4105S8Q sugar efflux transporter HVW55_09080 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HVW55_09085 ENOG4105DE4 1-phosphofructokinase HVW55_09090 ENOG4105DM4 PTS System HVW55_09095 ENOG4105DD7 kinase (PfkB family HVW55_09100 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HVW55_09105 ENOG4105D9N nucleoside HVW55_09110 ENOG4108Y4K DNA-binding transcriptional activator HVW55_09120 ENOG4105D9N nucleoside HVW55_09125 ENOG4105DD7 kinase (PfkB family HVW55_09135 ENOG4105HMI Membrane HVW55_09140 ENOG4105DUM transcriptional regulator, lysR family HVW55_09145 ENOG4108IQI permease HVW55_09150 ENOG4105D05 Receptor HVW55_09155 ENOG4105C4W S-formylglutathione hydrolase HVW55_09165 ENOG4105DHF Membrane HVW55_09170 ENOG41060NJ transcriptional regulator HVW55_09175 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HVW55_09180 ENOG4105C2J ABC transporter HVW55_09185 ENOG4108HWV )-transporter HVW55_09190 ENOG4107SJI Dehydrogenase HVW55_09195 ENOG4105BZ8 glutamate synthase HVW55_09200 ENOG4105Y9N Membrane HVW55_09205 ENOG4107GZ4 SanA protein HVW55_09215 ENOG41067MG lrgb family HVW55_09225 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HVW55_09235 ENOG4105ETP RND efflux system, outer membrane lipoprotein HVW55_09240 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HVW55_09245 ENOG4105KHU inner membrane protein YohD HVW55_09250 ENOG41069YE inner membrane protein yohC HVW55_09255 ENOG41061WM D-Alanyl-D-Alanine HVW55_09260 ENOG4105CXG d-lactate dehydrogenase HVW55_09265 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HVW55_09270 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HVW55_09275 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HVW55_09280 ENOG4108IJ8 ABC transporter HVW55_09285 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HVW55_09295 ENOG4108XDN Transcriptional regulator HVW55_09300 ENOG4108HRK Histidine kinase HVW55_09305 ENOG4108NEV two component transcriptional regulator, LytTR family HVW55_09310 ENOG4108W15 Protein of unknown function (DUF1456) HVW55_09315 ENOG4108YCW (LipO)protein HVW55_09320 ENOG410903U zinc ion binding HVW55_09325 ENOG4105DEG Vwa containing coxe family protein HVW55_09330 ENOG4105RD5 HVW55_09335 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HVW55_09345 ENOG4108KDT Molybdate metabolism regulator HVW55_09350 ENOG4108KDT Molybdate metabolism regulator HVW55_09360 ENOG4105D1F ATP-binding protein HVW55_09365 ENOG41067AK Protein of unknown function (DUF2574) HVW55_09370 ENOG41063W2 Fimbrial protein HVW55_09375 ENOG4108MQF Chaperone HVW55_09380 ENOG4105CW0 outer membrane usher protein HVW55_09385 ENOG410662B Type-1 fimbrial protein HVW55_09390 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HVW55_09395 ENOG41061MD high-affinity nickel-transporter HVW55_09410 ENOG4105DWF phosphomethylpyrimidine kinase HVW55_09415 ENOG4108UQ1 hydrolase, family 25 HVW55_09420 ENOG4105FDP GntR family transcriptional regulator HVW55_09425 ENOG4108TFM Kinase, PfkB family HVW55_09430 ENOG4108KD5 ADP-ribosylation crystallin J1 HVW55_09435 ENOG4105EAA nucleoside HVW55_09440 ENOG4105EIE fructose-bisphosphate aldolase HVW55_09455 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HVW55_09460 ENOG41090UW PTS System HVW55_09465 ENOG4105DT3 PTS system, galactitol-specific IIc component HVW55_09470 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HVW55_09485 ENOG41076Z6 Uncharacterized protein yegR HVW55_09490 ENOG4105CFP Peptidase U32 HVW55_09500 ENOG4105X54 addiction module antidote protein HVW55_09505 ENOG4105KWI UPF0339 protein HVW55_09510 ENOG4105E3W Two component transcriptional regulator (Winged helix family HVW55_09515 ENOG4105EB3 Histidine kinase HVW55_09530 ENOG4105BZS acriflavin resistance protein HVW55_09555 ENOG4108M24 von Willebrand factor, type A HVW55_09560 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HVW55_09565 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HVW55_09570 ENOG4105R8A Heat shock protein HVW55_09575 ENOG4105D03 DNA-3-methyladenine glycosylase II HVW55_09580 ENOG4105BZU Histidine kinase HVW55_09585 ENOG4105DBI uridine monophosphokinase HVW55_09595 ENOG4108GAE asmA family HVW55_09610 ENOG4105EE5 Membrane protein terC HVW55_09620 ENOG4105DAY polysaccharide export protein HVW55_09625 ENOG4105KJF protein tyrosine phosphatase HVW55_09630 ENOG4105D75 Capsular exopolysaccharide family HVW55_09635 ENOG41090RK glycosyl transferase HVW55_09640 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HVW55_09645 ENOG4107RXY Glycosyl transferase HVW55_09650 ENOG4108NYJ Colanic acid HVW55_09655 ENOG4105ECJ Glycosyl Transferase HVW55_09660 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HVW55_09665 ENOG4105C0K Gdp-mannose 4,6-dehydratase HVW55_09670 ENOG4105C30 Nad-dependent epimerase dehydratase HVW55_09675 ENOG4105FGF GDP-mannose mannosyl hydrolase HVW55_09680 ENOG4106CD9 glycosyl transferase group 1 HVW55_09685 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HVW55_09690 ENOG4107QKV phosphomannomutase HVW55_09695 ENOG4105D3Q Sugar transferase HVW55_09700 ENOG4105PSV Polysaccharide Biosynthesis Protein HVW55_09705 ENOG4105C74 pyruvyl transferase HVW55_09710 ENOG4107T8Q Glycosyl transferase (Group 1 HVW55_09715 ENOG4105G1A colanic acid biosynthesis protein HVW55_09720 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HVW55_09730 ENOG4108SHN Glycosyl transferase, family 2 HVW55_09740 ENOG4105CG5 Glycosyl transferase (Group 1 HVW55_09750 ENOG4107T8Q Glycosyl transferase (Group 1 HVW55_09755 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HVW55_09775 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HVW55_09795 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HVW55_09800 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HVW55_09805 ENOG4105CIH Imidazole acetol-phosphate transaminase HVW55_09810 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HVW55_09825 ENOG4107SRH Nad-dependent epimerase dehydratase HVW55_09830 ENOG4105EQ1 Transcriptional regulator HVW55_09840 ENOG4105CUB amino acid HVW55_09845 ENOG4105CUC YeeE YedE family protein HVW55_09855 ENOG4105CJB Exodeoxyribonuclease I HVW55_09860 ENOG4105DZ1 carboxypeptidase HVW55_09870 ENOG4105DR8 Membrane HVW55_09885 ENOG4108YZT Adenosylcobinamide kinase HVW55_09895 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) HVW55_09900 ENOG4108PXI ErfK YbiS YcfS YnhG HVW55_09910 ENOG4106P55 Transcriptional regulator HVW55_09915 ENOG4107R11 Transcriptional regulator HVW55_09925 ENOG4105UQX Mate efflux family protein HVW55_09935 ENOG4105CDY transcriptional regulatory protein HVW55_09940 ENOG4105FYV Amp nucleosidase HVW55_09945 ENOG4105CSH Transporter HVW55_09955 ENOG4105TNG K13735 adhesin invasin HVW55_09965 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) HVW55_09975 ENOG4108VKM cytochrome b561 HVW55_09980 ENOG4108MEK Metal-binding protein YodA HVW55_09985 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) HVW55_09990 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) HVW55_09995 ENOG4105VT2 5-hydroxyisourate hydrolase HVW55_10000 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HVW55_10005 ENOG4107ZY3 Histidine kinase HVW55_10010 ENOG4105TMR Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity) HVW55_10020 ENOG4105ZIT Porin Gram-negative type HVW55_10025 ENOG4105Y0K Inner membrane protein YedR HVW55_10030 ENOG4105EST Metal Dependent Phosphohydrolase HVW55_10035 ENOG4105DVF Cytosine-specific methyltransferase HVW55_10040 ENOG41090BB DNA mismatch endonuclease (vsr) HVW55_10045 ENOG4105FDR Membrane HVW55_10050 ENOG4105CKW Inner membrane protein yedI HVW55_10055 ENOG4105VNZ cytoplasmic protein HVW55_10060 ENOG4105BZU Histidine kinase HVW55_10065 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HVW55_10070 ENOG4105YX3 cellular response to acidity HVW55_10080 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HVW55_10085 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HVW55_10095 ENOG4105CN7 Flagellar biosynthetic protein FliP HVW55_10100 ENOG4105K0P flagellar biosynthesis protein HVW55_10105 ENOG4105DD5 Flagellar motor switch protein HVW55_10110 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HVW55_10115 ENOG4107ZI8 flagellar basal body-associated protein flil HVW55_10120 ENOG4105WF4 Flagellar hook-length control protein HVW55_10125 ENOG4105GSA Flagellar export protein flij HVW55_10130 ENOG4108JIR Flagellum-specific ATP synthase HVW55_10135 ENOG41090PJ Flagellar assembly protein HVW55_10140 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HVW55_10145 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HVW55_10160 ENOG4108HF7 Gcn5-related n-acetyltransferase HVW55_10165 ENOG4108RAV Conserved protein HVW55_10175 ENOG41066VF YeeE YedE family protein HVW55_10180 ENOG4108W9D (LipO)protein HVW55_10185 ENOG4105E5K Alpha-amylase HVW55_10195 ENOG4105MQ3 flagellar protein FliS HVW55_10200 ENOG4105DTS flagellar hook-associated HVW55_10205 ENOG4105I03 Flagellin HVW55_10210 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HVW55_10215 ENOG4108M9K flagella biosynthesis protein FliZ HVW55_10220 ENOG4105EAB amino acid AbC transporter HVW55_10225 ENOG4105K6H D-cysteine desulfhydrase HVW55_10230 ENOG4105E5Q amino acid AbC transporter HVW55_10235 ENOG4105CDA abc transporter atp-binding protein HVW55_10240 ENOG4105VJY transcriptional regulator HVW55_10245 ENOG4105XVG cytoplasmic protein HVW55_10255 ENOG4105WH1 Two component transcriptional regulator luxr family HVW55_10285 ENOG4106RHG Yeca family HVW55_10290 ENOG4105E0U tyrosine-specific transport protein HVW55_10295 ENOG4105VVZ metal-binding protein HVW55_10300 ENOG41090A1 ferritin HVW55_10305 ENOG4105P23 (LipO)protein HVW55_10315 ENOG4105N4N Protein of unknown function (DUF2766) HVW55_10320 ENOG4108UEC Ferritin-like protein HVW55_10325 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HVW55_10330 ENOG4105C2J ABC transporter HVW55_10335 ENOG4105CNN ABC, transporter HVW55_10340 ENOG4108K4C ec 3.1.3.12 HVW55_10350 ENOG4108VA4 Universal stress protein HVW55_10360 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HVW55_10365 ENOG4107RD7 Flagellar Motor Protein, MotA HVW55_10370 ENOG4105ER2 Ompa motb domain protein HVW55_10375 ENOG4105CBS Chea signal transduction histidine kinase HVW55_10380 ENOG4108V3W Chemotaxis protein, CheW HVW55_10385 ENOG4105C8Q Methyl-accepting chemotaxis HVW55_10390 ENOG4105C8Q Methyl-accepting chemotaxis HVW55_10395 ENOG4105BZU Histidine kinase HVW55_10405 ENOG4108VYJ response regulator receiver protein HVW55_10410 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HVW55_10420 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein HVW55_10425 ENOG4105D00 flagellar biosynthetic protein flhB HVW55_10430 ENOG4105D7B Flagellar biosynthesis protein flha HVW55_10435 ENOG4105W13 flagellar protein HVW55_10445 ENOG4105C75 arginyL-tRNA synthetase HVW55_10450 ENOG4106ZCM YecM protein HVW55_10460 ENOG4105CUW cytochrome C-TYPE protein HVW55_10465 ENOG4108J2R molybdopterin oxidoreductase HVW55_10480 ENOG4105WJG Glutathione HVW55_10485 ENOG41081XQ Conserved Protein HVW55_10490 ENOG4105D3W isochorismatase HVW55_10500 ENOG4108TIT dATP pyrophosphohydrolase HVW55_10505 ENOG4105CDY transcriptional regulatory protein HVW55_10515 ENOG4107S01 Repressor protein MetJ HVW55_10535 ENOG4105FAV ABC, transporter HVW55_10545 ENOG4105NXV High-affinity zinc uptake system protein HVW55_10550 ENOG4105DR5 peptidase HVW55_10555 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HVW55_10560 ENOG4105CA9 Pyruvate kinase HVW55_10565 ENOG4106KNT transcriptional regulator HVW55_10570 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HVW55_10575 ENOG4105C01 Dihydroxy-acid dehydratase HVW55_10580 ENOG4108UHU Aldolase HVW55_10590 ENOG4105X2V dna damage-inducible protein HVW55_10600 ENOG4108Q2J Inner membrane protein YebE HVW55_10605 ENOG4105CUG Oligopeptidase b HVW55_10610 ENOG4105UMD exodeoxyribonuclease X HVW55_10615 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HVW55_10620 ENOG4105MPK DNA polymerase III subunit theta HVW55_10625 ENOG4105FXM Copper resistance protein HVW55_10630 ENOG4108PNC copper resistance HVW55_10635 ENOG4105NKT exported protein HVW55_10640 ENOG4108R1E Serine threonine protein phosphatase 1 HVW55_10645 ENOG4105UVW uncharacterized protein yebW HVW55_10650 ENOG4105WT8 Protein of unknown function (DUF1480) HVW55_10660 ENOG4105DY2 Paraquat-inducible protein b HVW55_10665 ENOG4105H2K paraquat-inducible protein a HVW55_10670 ENOG4108ZGC gaf domain protein HVW55_10680 ENOG4105CN1 protease HVW55_10690 ENOG4105C0R drug resistance transporter emrb qaca subfamily HVW55_10695 ENOG4105J4Q Transcriptional regulator HVW55_10700 ENOG4105TIK HVW55_10710 ENOG4105Q3Y exported protein HVW55_10725 ENOG4105DHI Methyltransferase HVW55_10740 ENOG4105F3R pts system mannose fructose sorbose family iid HVW55_10745 ENOG4105ETZ PTS System HVW55_10750 ENOG4105DAS pts system HVW55_10755 ENOG4105EE5 Membrane protein terC HVW55_10760 ENOG4107XTP (EAL) domain protein HVW55_10765 ENOG4105EJQ L-serine dehydratase HVW55_10775 ENOG4105CRQ synthase (Component I) HVW55_10785 ENOG4105V2F Uncharacterized protein yoac HVW55_10790 ENOG4105M4H endoribonuclease L-psp HVW55_10795 ENOG4105DVT helicase HVW55_10800 ENOG41072GX Peptidase M22 Glycoprotease HVW55_10805 ENOG4105Y4Z Outer Membrane Lipoprotein HVW55_10810 ENOG4105CEY Amp-dependent synthetase and ligase HVW55_10815 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HVW55_10820 ENOG4105E3J oxidoreductase HVW55_10825 ENOG4105DVW rieske (2Fe-2S) HVW55_10830 ENOG4105C94 Transporter HVW55_10835 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HVW55_10840 ENOG4105EJC lysr family transcriptional regulator HVW55_10850 ENOG4108YS1 cytoplasmic protein HVW55_10855 ENOG4105YP6 Domain of unknown function (DUF1869) HVW55_10860 ENOG4105Y3U Transglycosylase-associated protein HVW55_10870 ENOG4106G4W HVW55_10875 ENOG410620I Diguanylate cyclase HVW55_10880 ENOG4105UCG Domain of unknown function (DUF333) HVW55_10885 ENOG4105K78 MarR family Transcriptional regulator HVW55_10890 ENOG4105DJ2 Major Facilitator Superfamily HVW55_10895 ENOG4105R1U AraC Family Transcriptional Regulator HVW55_10910 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HVW55_10915 ENOG4108KHP Diguanylate cyclase HVW55_10920 ENOG4106KTS Inner membrane protein yeaI HVW55_10930 ENOG4105CYN Serine protein kinase HVW55_10935 ENOG4105GNX MltA-interacting MipA family protein HVW55_10940 ENOG4105CV8 reductase HVW55_10945 ENOG4105DSB aldose 1-epimerase HVW55_10950 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HVW55_10960 ENOG4105VUT cytoplasmic protein HVW55_10965 ENOG4105CPQ Dehydrogenase HVW55_10970 ENOG4107TE1 transport protein HVW55_10975 ENOG4105CPQ Dehydrogenase HVW55_10980 ENOG4105D2N Aldolase HVW55_10985 ENOG4107UH8 sugar kinase HVW55_10990 ENOG4105CPC Aldo Keto reductase HVW55_10995 ENOG4105E98 transcriptional regulator DeoR family HVW55_11005 ENOG4108RWI nicotinamidase HVW55_11010 ENOG4105HDK L-asparaginase HVW55_11020 ENOG4105D07 Signal peptide peptidase, SppA HVW55_11025 ENOG41069NU Nitroreductase HVW55_11030 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HVW55_11035 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HVW55_11040 ENOG41065FB inner membrane protein ynji HVW55_11045 ENOG4105D82 Glutamate dehydrogenase HVW55_11050 ENOG4105MTM Protein of unknown function (DUF1496) HVW55_11055 ENOG4105M6F mutator MutT protein HVW55_11060 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HVW55_11065 ENOG4107RM6 sulfurtransferase HVW55_11070 ENOG4108VGW abc transporter atp-binding protein HVW55_11075 ENOG4105CXZ ABC transporter, permease HVW55_11080 ENOG4105VNH ABC transporter solute-binding protein HVW55_11085 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HVW55_11090 ENOG4108N5C SNARE associated Golgi protein-related protein HVW55_11095 ENOG4108KCW iron-sulfur cluster binding HVW55_11100 ENOG4108RSN SNARE associated Golgi HVW55_11105 ENOG4105CGK Exodeoxyribonuclease III HVW55_11120 ENOG4105C26 Dehydrogenase HVW55_11135 ENOG4108SPG Periplasmic Protein HVW55_11145 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HVW55_11150 ENOG4107RA1 nh(3)-dependent nad( ) synthetase HVW55_11155 ENOG4105KKI DNA-binding transcriptional activator OsmE HVW55_11160 ENOG4105VZJ PTS System HVW55_11165 ENOG4105CK1 PTS System HVW55_11170 ENOG4105VCP PTS System HVW55_11175 ENOG4105EZV Transcriptional regulator HVW55_11180 ENOG4105F8D glycoside hydrolase family 4 HVW55_11190 ENOG4105CH6 catalase HVW55_11205 ENOG4108ETY sodium dicarboxylate symporter HVW55_11210 ENOG4107K5X Membrane-bound metal-dependent hydrolase HVW55_11215 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HVW55_11220 ENOG4107PN8 YfeABCD locus regulator HVW55_11230 ENOG4105P10 Uncharacterized protein ydiZ HVW55_11235 ENOG4105DE4 1-phosphofructokinase HVW55_11240 ENOG4108NE3 Salt-induced outer membrane protein HVW55_11260 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HVW55_11265 ENOG41082NX 50s ribosomal protein l35 HVW55_11285 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) HVW55_11300 ENOG4108V06 Glutathione peroxidase HVW55_11310 ENOG4108QBX (LipO)protein HVW55_11315 ENOG4108TC0 Diguanylate phosphodiesterase HVW55_11330 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HVW55_11340 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HVW55_11345 ENOG4107QPK )-transporter HVW55_11350 ENOG4105C5I Dehydrogenase HVW55_11360 ENOG41061TZ Short-chain dehydrogenase reductase Sdr HVW55_11365 ENOG4105CEY Amp-dependent synthetase and ligase HVW55_11370 ENOG41090P5 ferredoxin-like protein HVW55_11375 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HVW55_11380 ENOG4105C10 Electron transfer flavoprotein HVW55_11385 ENOG4105CV7 Electron transfer flavoprotein HVW55_11390 ENOG4105W4W Transcriptional regulator HVW55_11395 ENOG4105C1G acyl-Coa dehydrogenase HVW55_11400 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HVW55_11415 ENOG4105EMV Major Facilitator HVW55_11420 ENOG4105EMV Major Facilitator HVW55_11425 ENOG4105SUA Ydil protein HVW55_11435 ENOG4105IPI Membrane HVW55_11440 ENOG4105CQB FAD linked oxidase domain protein HVW55_11445 ENOG4105KA0 thioesterase Superfamily protein HVW55_11450 ENOG410671Z uncharacterized protein ydiH HVW55_11455 ENOG4108Z4V iron-sulfur cluster assembly HVW55_11460 ENOG4105DIW FeS assembly protein SUFB HVW55_11465 ENOG4105C3K feS assembly ATPase SufC HVW55_11470 ENOG4105JRK feS assembly protein SufD HVW55_11485 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HVW55_11490 ENOG4105KMX major outer membrane lipoprotein HVW55_11495 ENOG4105CA9 Pyruvate kinase HVW55_11500 ENOG4105RFR Protein of unknown function (DUF2767) HVW55_11505 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HVW55_11510 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HVW55_11515 ENOG4105JVW HVW55_11520 ENOG4108393 oxidoreductase Fe-S subunit HVW55_11525 ENOG4108NWD Cytochrome HVW55_11530 ENOG4108Y7C Conserved Protein HVW55_11535 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HVW55_11540 ENOG4105N0V mono-oxygenase ydhR HVW55_11560 ENOG4107QI1 Mate efflux family protein HVW55_11565 ENOG4108R6K riboflavin synthase, subunit alpha HVW55_11570 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HVW55_11575 ENOG4105CZQ inner membrane transport protein YdhC HVW55_11580 ENOG4105F52 Transcriptional regulator HVW55_11595 ENOG4105F27 Major Facilitator HVW55_11600 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HVW55_11605 ENOG4105K4H Nlp p60 protein HVW55_11610 ENOG4105M2J Glutaredoxin HVW55_11615 ENOG4107QRT dEAD DEAH box helicase HVW55_11625 ENOG4108UYE Lactoylglutathione lyase HVW55_11630 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HVW55_11635 ENOG4108WUH Transcriptional regulator, TetR family HVW55_11640 ENOG4105XZD Fe-S protein HVW55_11645 ENOG4107RGM aldo keto reductase HVW55_11650 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HVW55_11655 ENOG4105DSW Fusaric acid resistance protein HVW55_11660 ENOG4105Y49 secretion protein, HlyD family HVW55_11675 ENOG4108XTF Outer Membrane Lipoprotein HVW55_11685 ENOG410642K Lysozyme inhibitor HVW55_11700 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HVW55_11705 ENOG4108K3A Glutathione S-transferase HVW55_11710 ENOG4105DUX Transporter HVW55_11715 ENOG4105CSM endonuclease III HVW55_11725 ENOG4108UQQ Electron transport complex HVW55_11750 ENOG4105M9B inner membrane protein ydgK HVW55_11755 ENOG4105QZ5 OriC-binding nucleoid-associated protein HVW55_11760 ENOG4106C6R beta-lactam resistance protein HVW55_11775 ENOG4105C87 Aminotransferase class I and II HVW55_11780 ENOG4105CI1 PTS System HVW55_11785 ENOG4107P2S Transcriptional regulator HVW55_11790 ENOG4107ZQV short-chain dehydrogenase reductase HVW55_11795 ENOG4105XEA Tetr family transcriptional regulator HVW55_11800 ENOG4105CNT hydrolase family 2 HVW55_11805 ENOG4105CT4 transporter HVW55_11810 ENOG4108QNI outer membrane porin protein HVW55_11815 ENOG4106J39 exported protein HVW55_11820 ENOG4105EIP mannose-6-phosphate isomerase HVW55_11825 ENOG4107GFK fumarate HVW55_11830 ENOG4105C9Q fumarate hydratase class II HVW55_11840 ENOG4105JJR Histidine kinase HVW55_11845 ENOG4107EXC regulatoR HVW55_11850 ENOG4105RA2 Membrane HVW55_11860 ENOG4105D5Q Arginine ornithine antiporter HVW55_11865 ENOG4105C5D exported protein HVW55_11870 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HVW55_11875 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HVW55_11880 ENOG4105DSF transport protein HVW55_11895 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HVW55_11910 ENOG4105D94 Major Facilitator Superfamily HVW55_11915 ENOG4106NZI LysR family Transcriptional regulator HVW55_11920 ENOG4105DAG ROK family HVW55_11925 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HVW55_11935 ENOG4108NEM leader-binding protein dmsD HVW55_11940 ENOG4107KGK dmso reductase anchor subunit HVW55_11945 ENOG4105QAX Iron-sulfur HVW55_11950 ENOG4105C3J Cysteine desulfurase HVW55_11955 ENOG4107QY8 reductase HVW55_11960 ENOG4105KBG Protein of unknown function (DUF1161) HVW55_11965 ENOG4105D69 UPF0257 lipoprotein ynfC HVW55_11970 ENOG4108MK9 spermidine N(1)-acetyltransferase HVW55_11985 ENOG4105CXK mandelate racemase muconate lactonizing HVW55_11990 ENOG4105CPQ Dehydrogenase HVW55_12000 ENOG4107R08 Integrase HVW55_12015 ENOG4108YXQ IS66 Orf2 family protein HVW55_12020 ENOG4105E5H Transposase HVW55_12035 ENOG4106G8A Qin prophage HVW55_12055 ENOG41087BU transcriptional repressor DicA HVW55_12110 ENOG4105K4U addiction module toxin, RelE StbE family HVW55_12130 ENOG4108MXB Protein of unknown function (DUF968) HVW55_12135 ENOG4105HGD Antitermination protein HVW55_12150 ENOG4105VEQ Cold shock protein HVW55_12155 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HVW55_12170 ENOG4108YV9 Protein of unknown function (DUF2514) HVW55_12175 ENOG4105VEQ Cold shock protein HVW55_12190 ENOG4106IAW HVW55_12195 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HVW55_12200 ENOG41064WM Uncharacterized protein YcgX HVW55_12205 ENOG4106YSC HVW55_12210 ENOG4105FKG DNA packaging protein HVW55_12215 ENOG4105UZW Tail fiber assembly protein HVW55_12220 ENOG4107DE1 head-to-tail joining protein HVW55_12230 ENOG4105F7J membrane-bound serine protease HVW55_12240 ENOG4105IM0 capsid protein HVW55_12315 ENOG4105UZW Tail fiber assembly protein HVW55_12320 ENOG4105MN3 Resolvase HVW55_12325 ENOG4105W3V DNA-binding, transcriptional regulator HVW55_12340 ENOG4105DEI Mannitol dehydrogenase HVW55_12345 ENOG41061EV selenium-binding protein YdfZ HVW55_12350 ENOG4107XBN GntR Family Transcriptional Regulator HVW55_12355 ENOG4105EMU Dehydrogenase HVW55_12360 ENOG4105DGW oligopeptidase A HVW55_12365 ENOG4108WTK competence damage-inducible protein HVW55_12370 ENOG4108YDI single-species biofilm formation on inanimate substrate HVW55_12385 ENOG4105E5W Transporter HVW55_12390 ENOG4108594 Permease of the drug metabolite transporter HVW55_12395 ENOG4105FDP GntR family transcriptional regulator HVW55_12405 ENOG4105CK1 PTS System HVW55_12410 ENOG4105VCP PTS System HVW55_12420 ENOG4105CS2 ec 3.2.1.21 HVW55_12425 ENOG4106DNR multiple antibiotic resistance protein HVW55_12430 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HVW55_12435 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HVW55_12455 ENOG4105EGI Transcriptional regulator HVW55_12460 ENOG4105C26 Dehydrogenase HVW55_12465 ENOG4105CSV Glutaminase HVW55_12470 ENOG4105M0C cytoplasmic protein HVW55_12475 ENOG4105BZU Histidine kinase HVW55_12485 ENOG4105FFC UPF0187 protein HVW55_12490 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) HVW55_12495 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HVW55_12520 ENOG4105C2J ABC transporter HVW55_12530 ENOG4107RYS Autoinducer-2 (AI-2) kinase HVW55_12545 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HVW55_12550 ENOG4105CAF HipA N-terminal domain protein HVW55_12560 ENOG4108RQP Major type 1 subunit fimbrin HVW55_12570 ENOG4105CW0 outer membrane usher protein HVW55_12575 ENOG4108WDE Fimbrial protein HVW55_12580 ENOG4106318 fimbrial-like protein YdeR HVW55_12585 ENOG4106PIH fimbrial-like protein ydeQ HVW55_12590 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HVW55_12605 ENOG4105ENH Sulfatase HVW55_12610 ENOG4105C4X radical SAM domain protein HVW55_12620 ENOG4105CQ0 ABC transporter HVW55_12625 ENOG4105PE1 Receptor HVW55_12630 ENOG4107RAN Peptidase, M16 HVW55_12635 ENOG4105CVK Glutamate decarboxylase HVW55_12640 ENOG4105E5D amino acid HVW55_12645 ENOG4105F32 YngK protein HVW55_12655 ENOG4105BZU Histidine kinase HVW55_12660 ENOG4105BZU Histidine kinase HVW55_12665 ENOG4108UQS dipeptidase HVW55_12670 ENOG4105DEF Extracellular solute-binding protein, family 5 HVW55_12675 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HVW55_12680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HVW55_12685 ENOG4105C3U ABC transporter HVW55_12690 ENOG4107H6U ABC transporter HVW55_12695 ENOG4105DUM transcriptional regulator, lysR family HVW55_12700 ENOG4107QP7 CoA-transferase subunit A HVW55_12705 ENOG4107QNJ CoA-transferase subunit B HVW55_12710 ENOG4105CHU acetyl-coa acetyltransferase HVW55_12715 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HVW55_12720 ENOG4105CY2 Citrate transporter HVW55_12725 ENOG4105DTD Dehydrogenase HVW55_12730 ENOG4108Z9K Osmotically inducible protein HVW55_12735 ENOG4105TPS biofilm-dependent modulation protein HVW55_12740 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HVW55_12750 ENOG4105DQ4 alcohol dehydrogenase HVW55_12760 ENOG41084S7 Plasmid maintenance system antidote protein HVW55_12765 ENOG4108MG3 formate dehydrogenase HVW55_12770 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HVW55_12780 ENOG4105RPH Inner membrane protein YddG HVW55_12790 ENOG4108UI3 Leucine Rich repeat HVW55_12795 ENOG4108UI3 Leucine Rich repeat HVW55_12800 ENOG4107QND Nitrite extrusion protein HVW55_12805 ENOG4105CRU nitrate reductase, alpha subunit HVW55_12810 ENOG4108IUE nitrate reductase beta subunit HVW55_12815 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HVW55_12820 ENOG4105D0D Nitrate reductase 2, gamma subunit HVW55_12825 ENOG4105JAB phenazine biosynthesis protein, phzf family HVW55_12830 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HVW55_12835 ENOG4108MEJ flavin reductase domain protein HVW55_12845 ENOG410600T transposase HVW55_12850 ENOG4105EKQ RNA-directed DNA polymerase HVW55_12870 ENOG4105CS6 Rhs element vgr protein HVW55_12880 ENOG4108N27 Glutathione S-transferase HVW55_12885 ENOG4105C85 amino acid HVW55_12890 ENOG4108NS2 receptor HVW55_12895 ENOG4105CHB tonB-dependent Receptor HVW55_12900 ENOG4108WYP Transcriptional regulator HVW55_12905 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HVW55_12910 ENOG4108Z7F N-acetyltransferase HVW55_12915 ENOG4108T9Y Inner membrane protein ydcZ HVW55_12920 ENOG4105R71 cytoplasmic protein HVW55_12925 ENOG410654E Membrane HVW55_12940 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HVW55_12945 ENOG4105D81 ABC transporter, permease HVW55_12950 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HVW55_12955 ENOG4107TYH extracellular solute-binding protein family 1 HVW55_12960 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HVW55_12965 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HVW55_12975 ENOG4105RR0 Protein of unknown function (DUF2554) HVW55_12980 ENOG4105CFP Peptidase U32 HVW55_12985 ENOG4108JCI Transcriptional regulator HVW55_12990 ENOG4105DKK Benzoate HVW55_12995 ENOG4108KKZ (LipO)protein HVW55_13000 ENOG41088CC tellurite resistance protein tehB HVW55_13005 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HVW55_13010 ENOG4107WE3 acetyltransferase YdcK HVW55_13015 ENOG4108Z9I -acetyltransferase HVW55_13020 ENOG4105Z2P Protein of unknown function (DUF465) HVW55_13030 ENOG4105E32 cytoplasmic protein HVW55_13035 ENOG4105DDW LysR family Transcriptional regulator HVW55_13040 ENOG4105C8Q Methyl-accepting chemotaxis HVW55_13045 ENOG4107NK6 Hok/gef family HVW55_13050 ENOG4105UPP uncharacterized protein ydcA HVW55_13055 ENOG4105CPW cytochrome b561 HVW55_13060 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HVW55_13065 ENOG4105C26 Dehydrogenase HVW55_13070 ENOG4107DB1 DUF218 domain HVW55_13075 ENOG4105CQ7 ATP-dependent helicase HVW55_13085 ENOG41077RS Phosphatase HVW55_13090 ENOG4105E8V Alpha Beta Hydrolase Fold protein HVW55_13095 ENOG4108HPI phosphatidate Cytidylyltransferase HVW55_13110 ENOG4107S5I aldo keto reductase HVW55_13115 ENOG4108Z0R Transferase HVW55_13120 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HVW55_13125 ENOG4105DZS Phenylacetate-CoA ligase HVW55_13130 ENOG4105CHU acetyl-coa acetyltransferase HVW55_13135 ENOG4108ZJI phenylacetic acid degradation protein HVW55_13140 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HVW55_13145 ENOG4108UKI Enoyl-CoA hydratase HVW55_13150 ENOG4105E39 Enoyl-CoA hydratase HVW55_13155 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HVW55_13160 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HVW55_13165 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HVW55_13170 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HVW55_13175 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HVW55_13180 ENOG4105DXM phenylacetic acid degradation protein HVW55_13185 ENOG4105F11 amine oxidase HVW55_13190 ENOG4105C26 Dehydrogenase HVW55_13195 ENOG4108WFR AraC Family Transcriptional Regulator HVW55_13200 ENOG4105WXT Conserved Protein HVW55_13205 ENOG410689M (LipO)protein HVW55_13210 ENOG4107H52 Dicarboxylate transport HVW55_13215 ENOG4105C5I Dehydrogenase HVW55_13220 ENOG41090X5 Heat shock protein hslJ HVW55_13225 ENOG4105IKK cytoplasmic protein HVW55_13230 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HVW55_13235 ENOG4105FCK Membrane HVW55_13240 ENOG4108RW8 Universal stress protein F HVW55_13255 ENOG4105W3V DNA-binding, transcriptional regulator HVW55_13260 ENOG4105MN3 Resolvase HVW55_13265 ENOG4105UZW Tail fiber assembly protein HVW55_13270 ENOG4108X9F tail fiber protein HVW55_13385 ENOG4108ES9 ParB domain protein nuclease HVW55_13390 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HVW55_13400 ENOG4105KUS lysozyme HVW55_13405 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HVW55_13415 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HVW55_13425 ENOG4105RWQ Protein of unknown function (DUF1364) HVW55_13460 ENOG4105JBR DNA replication protein HVW55_13465 ENOG4105ZTP Protein of unknown function (DUF1376) HVW55_13475 ENOG4105W7J DNA binding HVW55_13480 ENOG410649Z repressor HVW55_13500 ENOG4107C82 Rac prophage HVW55_13510 ENOG41076J9 exonuclease VIII HVW55_13515 ENOG4108PNI recT protein HVW55_13520 ENOG4106YAH restriction alleviation and modification enhancement HVW55_13525 ENOG41070YT Rac prophage HVW55_13530 ENOG4107160 Rac prophage HVW55_13535 ENOG4107R08 Integrase HVW55_13545 ENOG4105C1J atp-dependent rna helicase HVW55_13555 ENOG4105BZU Histidine kinase HVW55_13560 ENOG4108DG9 Smr protein MutS2 HVW55_13565 ENOG4106KR7 LysR family Transcriptional regulator HVW55_13570 ENOG4105CH2 amidohydrolase HVW55_13575 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HVW55_13580 ENOG4105CFC Transporter HVW55_13585 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HVW55_13590 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HVW55_13595 ENOG4105Q9Y Universal stress protein HVW55_13600 ENOG4105S5I Membrane HVW55_13605 ENOG4105D64 Mechanosensitive ion channel HVW55_13610 ENOG4107QSI ABC, transporter HVW55_13615 ENOG4105EQ2 LysR family Transcriptional regulator HVW55_13620 ENOG4105ENX hydrolase HVW55_13635 ENOG4105KXI murein peptide amidase A HVW55_13640 ENOG4107S8C mandelate racemase muconate lactonizing HVW55_13645 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HVW55_13650 ENOG4108JU8 Transcriptional regulator HVW55_13660 ENOG4105CM6 amino acid regulated cytosolic protein HVW55_13665 ENOG4105FKQ transcriptional regulator HVW55_13670 ENOG4107EFV Outer membrane protein G HVW55_13675 ENOG4108IJ9 (ABC) transporter HVW55_13680 ENOG4107URF beta-phospho-glucomutase HVW55_13685 ENOG4105C71 hydrolase family 65, central catalytic HVW55_13690 ENOG4105CK5 oxidoreductase HVW55_13695 ENOG4107TYA transient receptor potential locus HVW55_13700 ENOG4107RRD Dehydrogenase HVW55_13705 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HVW55_13710 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HVW55_13715 ENOG4105WEM extracellular solute-binding protein HVW55_13720 ENOG4107QW3 Sucrose phosphorylase HVW55_13725 ENOG4105K8Z Phage shock protein HVW55_13730 ENOG4105NNG Peripheral inner membrane phage-shock protein HVW55_13735 ENOG4105FM1 phage shock protein C HVW55_13740 ENOG4105YYT phage shock protein B HVW55_13745 ENOG41087YS Phage shock protein A HVW55_13750 ENOG4105E51 psp operon transcriptional activator HVW55_13755 ENOG4108JPW Aminotransferase HVW55_13760 ENOG4105CJP fad dependent oxidoreductase HVW55_13765 ENOG4105C26 Dehydrogenase HVW55_13770 ENOG4107VRI Transcriptional regulator HVW55_13775 ENOG4108Z86 Glutamine amidotransferase HVW55_13780 ENOG4105CFQ glutamine synthetase HVW55_13790 ENOG4105CUB amino acid HVW55_13795 ENOG4105N0E Protein of unknown function (DUF2543) HVW55_13800 ENOG4108HIY periplasmic HVW55_13805 ENOG4108I5W peptide transport system, permease protein HVW55_13810 ENOG4108EU3 peptide transport system, permease HVW55_13815 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HVW55_13820 ENOG4108JQ2 peptide transport system atp-binding protein HVW55_13825 ENOG4105C2C drug resistance transporter, Bcr CflA HVW55_13835 ENOG4105BZS acriflavin resistance protein HVW55_13840 ENOG4105C1P efflux transporter, rnd family, mfp subunit HVW55_13845 ENOG41067SE Tetr family transcriptional regulator HVW55_13850 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HVW55_13855 ENOG4105Q4T oxidoreductase HVW55_13870 ENOG4105BZU Histidine kinase HVW55_13875 ENOG410643D UPF0509 protein HVW55_13880 ENOG4105N2W Transcriptional regulator HVW55_13890 ENOG4108ZJT translation initiation factor, Sui1 HVW55_13900 ENOG4105CFV Tetratricopeptide repeat protein HVW55_13905 ENOG4105Q4A inner membrane protein yciS HVW55_13910 ENOG4105EYK Phosphatidylglycerophosphatase B HVW55_13920 ENOG4107QM5 aconitate hydratase HVW55_13940 ENOG4107R11 Transcriptional regulator HVW55_13945 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HVW55_13950 ENOG4105RKX Protein of unknown function (DUF2498) HVW55_13955 ENOG4105ERU peptidase HVW55_13960 ENOG4105UBK short-chain dehydrogenase reductase HVW55_13965 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HVW55_13970 ENOG4105FE9 pseudouridine synthase HVW55_13975 ENOG4105EG3 transmembrane signal peptide protein HVW55_13980 ENOG4107RTD sua5 ycio yrdc ywlc family protein HVW55_13985 ENOG4105DB7 PHP domain protein HVW55_13995 ENOG4105CRQ synthase (Component I) HVW55_14000 ENOG4108EFP Anthranilate synthase component II HVW55_14005 ENOG4105DK0 Indole-3-glycerol phosphate synthase HVW55_14025 ENOG4108Z9Z response to DNA damage stimulus HVW55_14030 ENOG4108N8X transition metal ion binding HVW55_14035 ENOG4105EIF outer membrane protein W HVW55_14055 ENOG4105NAU thioesterase Superfamily protein HVW55_14060 ENOG410822N TonB family HVW55_14065 ENOG4105K9H YciI-like protein HVW55_14070 ENOG4107SVH Potassium channel protein HVW55_14090 ENOG4108JQ7 (ABC) transporter HVW55_14095 ENOG4105C3U ABC transporter HVW55_14100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HVW55_14105 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HVW55_14110 ENOG4108J59 Extracellular solute-binding protein, family 5 HVW55_14115 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HVW55_14120 ENOG4105C0A alcohol dehydrogenase HVW55_14125 ENOG4105VNT transposase (IS4 family) protein HVW55_14135 ENOG4108SAU DNA-binding protein H-ns HVW55_14140 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HVW55_14145 ENOG4105I93 response regulator HVW55_14150 ENOG4105D78 K07001 NTE family protein HVW55_14160 ENOG4105CIY formyltetrahydrofolate deformylase HVW55_14190 ENOG41076YT nitrate reductase, gamma subunit HVW55_14195 ENOG4105R3A Nitrate reductase HVW55_14200 ENOG4108IUE nitrate reductase beta subunit HVW55_14205 ENOG4105CRU nitrate reductase, alpha subunit HVW55_14210 ENOG4105DQQ Major facilitator superfamily MFS_1 HVW55_14215 ENOG4105BZU Histidine kinase HVW55_14220 ENOG4105WH1 Two component transcriptional regulator luxr family HVW55_14225 ENOG4105ID0 Putative invasin HVW55_14230 ENOG41090EX DsrE family HVW55_14235 ENOG4108NH8 Cation transport protein HVW55_14240 ENOG4105WS7 Cation transport regulator HVW55_14245 ENOG4105EWV Sodium calcium exchanger membrane region HVW55_14265 ENOG41063JG Transcriptional regulator HVW55_14270 ENOG4108YY7 Invasion gene expression up-regulator SirB HVW55_14275 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HVW55_14300 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HVW55_14305 ENOG4105CHH sulfate transporter HVW55_14310 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HVW55_14320 ENOG4105C3G gtp-binding protein HVW55_14325 ENOG4105I1J Autotransporter HVW55_14330 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HVW55_14335 ENOG4105CMT Dihydroxyacetone kinase HVW55_14340 ENOG4108UTZ Dihydroxyacetone kinase HVW55_14345 ENOG4105VDH Dihydroxyacetone kinase HVW55_14355 ENOG4105S10 periplasmic binding protein HVW55_14360 ENOG4105EHG Permease protein HVW55_14365 ENOG4105E0A ABC, transporter HVW55_14370 ENOG4108BSC Methyltransferase HVW55_14375 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HVW55_14390 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HVW55_14400 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HVW55_14420 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HVW55_14430 ENOG4105ED1 spovr family HVW55_14445 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HVW55_14450 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HVW55_14455 ENOG4105KT5 UmuD protein HVW55_14460 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HVW55_14470 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HVW55_14480 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HVW55_14485 ENOG4105S66 prophage protein HVW55_14495 ENOG4107QMS site-determining protein HVW55_14530 ENOG410658X HVW55_14545 ENOG4105BZU Histidine kinase HVW55_14555 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HVW55_14560 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HVW55_14565 ENOG4105BZU Histidine kinase HVW55_14570 ENOG4108XDN Transcriptional regulator HVW55_14575 ENOG41064WM Uncharacterized protein YcgX HVW55_14595 ENOG4108HMX isocitrate dehydrogenase (NADP) HVW55_14600 ENOG4108R99 pseudouridine synthase HVW55_14620 ENOG4107QTF adenylosuccinate lyase HVW55_14625 ENOG4105XJC Two component transcriptional regulator (Winged helix family HVW55_14630 ENOG4105IFJ Histidine kinase HVW55_14635 ENOG4105EZE Cupin 4 family protein HVW55_14645 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HVW55_14655 ENOG4105UZW Tail fiber assembly protein HVW55_14660 ENOG4108X9F tail fiber protein HVW55_14735 ENOG4105IM0 capsid protein HVW55_14775 ENOG4105IM0 capsid protein HVW55_14850 ENOG4107DE1 head-to-tail joining protein HVW55_14855 ENOG4105UZW Tail fiber assembly protein HVW55_14875 ENOG4105QYK bacteriophage lambda Bor protein homolog HVW55_14905 ENOG4105HRS Antitermination protein HVW55_14910 ENOG4105KSK (crossover) junction endodeoxyribonuclease HVW55_14915 ENOG4108MXB Protein of unknown function (DUF968) HVW55_14955 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) HVW55_14995 ENOG4106G8A Qin prophage HVW55_15010 ENOG4108I1J Integrase HVW55_15025 ENOG4105D38 putrescine abc transporter HVW55_15030 ENOG4107RUE extracellular solute-binding protein family 1 HVW55_15035 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HVW55_15045 ENOG4105D60 lipoprotein releasing system transmembrane protein HVW55_15050 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HVW55_15055 ENOG4105D60 lipoprotein releasing system transmembrane protein HVW55_15060 ENOG4105IQC Inner membrane protein YcfT HVW55_15065 ENOG4108JA2 transcriptioN-repair coupling factor HVW55_15070 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HVW55_15075 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HVW55_15080 ENOG4108IND Tetr family transcriptional regulator HVW55_15085 ENOG4107MBR 17 kDa surface antigen HVW55_15090 ENOG4105CEP NADH dehydrogenase HVW55_15105 ENOG4108RUM thiamine kinase HVW55_15110 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HVW55_15115 ENOG41090DQ Lipoprotein HVW55_15120 ENOG4105K59 histidine triad (HIT) protein HVW55_15125 ENOG4105CNM Receptor HVW55_15130 ENOG4105CI1 PTS System HVW55_15135 ENOG4105F8V Hydrolase, tatD family HVW55_15140 ENOG4107QRG dna polymerase iii HVW55_15150 ENOG4105HHA aminodeoxychorismate lyase HVW55_15155 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HVW55_15160 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HVW55_15165 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HVW55_15170 ENOG4105CHR reductase HVW55_15175 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HVW55_15195 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HVW55_15200 ENOG4108UHJ MAF-like protein HVW55_15205 ENOG4105EI2 Pseudouridine synthase HVW55_15210 ENOG4107QQB Ribonuclease E HVW55_15215 ENOG4105DTJ flagellar hook-associated protein HVW55_15220 ENOG4105E1Q flagellar hook-associated protein HVW55_15225 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HVW55_15240 ENOG4105CGA flagellar basal-body rod protein FlgG HVW55_15245 ENOG4108KPB Flagellar basal-body rod protein FlgF HVW55_15250 ENOG4105BZE flagellar hook protein, FlgE HVW55_15255 ENOG4105W00 Flagellar hook capping protein HVW55_15260 ENOG4108ZC9 flagellar basal-body rod protein flgc HVW55_15265 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HVW55_15270 ENOG4105CKS Flagella basal body P-ring formation protein flgA HVW55_15275 ENOG4105M9M anti-sigma28 factor FlgM HVW55_15280 ENOG4105QVD Flagella synthesis protein FlgN HVW55_15285 ENOG4105CJR Integral membrane protein (MviN HVW55_15290 ENOG4105EP9 oxidoreductase HVW55_15300 ENOG4105D9U N-acetyltransferase HVW55_15310 ENOG4105E9S glutaredoxin 2 HVW55_15315 ENOG4105F3T (LipO)protein HVW55_15320 ENOG4105EKE dihydroorotase HVW55_15325 ENOG4105MEA DNA damage-inducible protein i HVW55_15330 ENOG4105PVA Biofilm formation regulatory protein BssS HVW55_15340 ENOG4106974 biofilm formation HVW55_15345 ENOG4105DS1 cytochrome b561 HVW55_15350 ENOG4108YYC ycei family HVW55_15360 ENOG4105D1S lipid A biosynthesis HVW55_15370 ENOG4108W47 Acidic protein msyB HVW55_15375 ENOG4105NAC (LipO)protein HVW55_15380 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HVW55_15395 ENOG4107RZC phospholipase d HVW55_15400 ENOG4108UVJ appr-1-p processing domain protein HVW55_15415 ENOG41090QH cryptic curlin major subunit HVW55_15420 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HVW55_15425 ENOG41086KC Transcriptional regulator HVW55_15430 ENOG4108XDW curli assembly protein CsgE HVW55_15435 ENOG4108WYR Curli production assembly transport component, CsgF HVW55_15440 ENOG4105P8Q Curli production assembly transport component CsgG HVW55_15445 ENOG4108UQ5 membrane protein YcdZ HVW55_15450 ENOG4107XHZ cytoplasmic chaperone TorD family protein HVW55_15460 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HVW55_15470 ENOG4108T85 Membrane HVW55_15515 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HVW55_15520 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) HVW55_15530 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) HVW55_15540 ENOG41081XD Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) HVW55_15545 ENOG4105D5K Hemolysin activator protein HVW55_15550 ENOG4105CKT filamentous hemagglutinin HVW55_15560 ENOG4105X0I Fimbrial HVW55_15565 ENOG4108AF8 Chaperone HVW55_15570 ENOG4105CW0 outer membrane usher protein HVW55_15580 ENOG4108MQF Chaperone HVW55_15585 ENOG4105CHR reductase HVW55_15590 ENOG4108TC1 Transcriptional regulator HVW55_15600 ENOG4105CXC rtn protein HVW55_15605 ENOG4105BZU Histidine kinase HVW55_15610 ENOG4108TUY outer membrane protein PgaA HVW55_15615 ENOG4107BJW polysaccharide deacetylase HVW55_15620 ENOG4105CND Glycosyl transferase, family 2 HVW55_15630 ENOG4105D5M phosphate starvation-inducible protein HVW55_15640 ENOG410650H (LipO)protein HVW55_15655 ENOG4105CK7 Sodium proline symporter HVW55_15665 ENOG4105C26 Dehydrogenase HVW55_15670 ENOG4108R86 Transcriptional regulator HVW55_15705 ENOG4105C2W permease HVW55_15710 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HVW55_15720 ENOG4105XH3 HVW55_15725 ENOG4105D6F Phosphatase HVW55_15750 ENOG4107QY8 reductase HVW55_15755 ENOG4105CUW cytochrome C-TYPE protein HVW55_15760 ENOG4106WF9 DNA-binding transcriptional regulator TorR HVW55_15765 ENOG4108SV3 Tmao reductase system periplasmic protein tort HVW55_15770 ENOG4105BZU Histidine kinase HVW55_15775 ENOG4105HEE Binding Domain protein HVW55_15780 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HVW55_15795 ENOG4105VEQ Cold shock protein HVW55_15800 ENOG41060EU Cold shock-like protein HVW55_15810 ENOG4108Y9B (LipO)protein HVW55_15815 ENOG4108W78 Pfam:DUF1017 HVW55_15820 ENOG4105E3R (LipO)protein HVW55_15830 ENOG4105VNT transposase (IS4 family) protein HVW55_15840 ENOG4107ZF2 Phosphatase HVW55_15845 ENOG4108F2G Chain length determinant protein HVW55_15850 ENOG4105D6F Phosphatase HVW55_15860 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HVW55_15865 ENOG4105C4M (Ubiquinol oxidase) subunit I HVW55_15870 ENOG4105MVP hydrogenase-1 operon protein HyaF HVW55_15875 ENOG4108VXY Hydrogenase-1 operon protein HyaE HVW55_15880 ENOG4108USZ hydrogenase HVW55_15885 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HVW55_15890 ENOG4105DPX Hydrogenase, large subunit HVW55_15895 ENOG4105E3S small subunit HVW55_15905 ENOG4108MN8 Membrane HVW55_15910 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HVW55_15915 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HVW55_15930 ENOG4105K4P CoA-binding domain protein HVW55_15945 ENOG41088T4 Helicase IV HVW55_15950 ENOG410901E Membrane HVW55_15955 ENOG4105EM2 membrane HVW55_15960 ENOG4108RZ1 DNA transformation protein HVW55_15980 ENOG4105DAN ATP-dependent protease HVW55_15990 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HVW55_15995 ENOG4108Q2G (LipO)protein HVW55_16000 ENOG4105DY2 Paraquat-inducible protein b HVW55_16005 ENOG4105F1S paraquat-inducible protein a HVW55_16010 ENOG4105C5H ABC transporter HVW55_16020 ENOG4105QVC MOSC domain-containing protein HVW55_16025 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HVW55_16035 ENOG4106PH7 chaperone HVW55_16040 ENOG4105MX3 Fimbrial HVW55_16045 ENOG4105Q7J Fimbrial HVW55_16050 ENOG4108MDY Fimbrial HVW55_16055 ENOG4105CW0 outer membrane usher protein HVW55_16060 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HVW55_16065 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HVW55_16070 ENOG4108UZX fmn reductase HVW55_16075 ENOG4105GVF (ABC) transporter HVW55_16085 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HVW55_16090 ENOG4105E2Y ABC, transporter HVW55_16095 ENOG4105CD8 aminopeptidase N HVW55_16115 ENOG4105CGF Aromatic amino acid aminotransferase HVW55_16120 ENOG4105C5X domain protein HVW55_16125 ENOG4105EAQ (twin-arginine translocation) pathway signal HVW55_16130 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HVW55_16140 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HVW55_16150 ENOG4106371 Methyltransferase HVW55_16155 ENOG4107S90 membrAne HVW55_16160 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HVW55_16175 ENOG4105T0Z Conserved Protein HVW55_16185 ENOG4105BZ1 (ABC) transporter HVW55_16190 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HVW55_16200 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HVW55_16210 ENOG4108K0D peptidase, M48 HVW55_16215 ENOG4105VNT transposase (IS4 family) protein HVW55_16230 ENOG4107VMU Membrane HVW55_16235 ENOG4105DDY UPF0142 protein ycaO HVW55_16240 ENOG4105TMB Formate nitrite transporter HVW55_16245 ENOG4105C6N Formate acetyltransferase HVW55_16250 ENOG4105ZTC transcriptional activator, Ogr delta HVW55_16295 ENOG4105UZW Tail fiber assembly protein HVW55_16300 ENOG4108X9F tail fiber protein HVW55_16395 ENOG4105ED4 portal protein HVW55_16430 ENOG4105VZ1 Replication Protein HVW55_16475 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HVW55_16480 ENOG4105F1A Pyruvate formate-lyase HVW55_16490 ENOG4105E5D amino acid HVW55_16500 ENOG4105CHJ isochorismatase hydrolase HVW55_16505 ENOG4107KGK dmso reductase anchor subunit HVW55_16510 ENOG4105QAX Iron-sulfur HVW55_16515 ENOG4107QY8 reductase HVW55_16525 ENOG4105D1H recombination factor protein RarA HVW55_16535 ENOG4105CNU cell division protein FtsK HVW55_16545 ENOG4105C3M thioredoxin reductase HVW55_16550 ENOG4108JJ9 ABC, transporter HVW55_16555 ENOG4108JJ8 (ABC) transporter HVW55_16565 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HVW55_16575 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HVW55_16585 ENOG4105VEQ Cold shock protein HVW55_16590 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HVW55_16595 ENOG4105DJY efflux transporter, rnd family, mfp subunit HVW55_16600 ENOG4108MJ5 VirK protein HVW55_16605 ENOG4105CPB ATP-dependent endonuclease of the OLD family HVW55_16610 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HVW55_16615 ENOG4105DWU Membrane HVW55_16625 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HVW55_16630 ENOG4105C7K acetolactate synthase HVW55_16635 ENOG4105C5W Aldolase HVW55_16640 ENOG4105CGD Nad-dependent epimerase dehydratase HVW55_16645 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HVW55_16650 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HVW55_16665 ENOG41064MM (LipO)protein HVW55_16670 ENOG4105E5Z arginine transporter ATP-binding subunit HVW55_16675 ENOG4106PMH Extracellular solute-binding protein family 3 HVW55_16680 ENOG4105GBT ABC transporter HVW55_16685 ENOG4105DMR ABC, transporter HVW55_16690 ENOG4106TNF Periplasmic binding protein HVW55_16715 ENOG4105RBQ inner membrane protein ybjO HVW55_16720 ENOG4105D38 putrescine abc transporter HVW55_16725 ENOG4105F38 ABC transporter, permease HVW55_16730 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HVW55_16735 ENOG4107RUE extracellular solute-binding protein family 1 HVW55_16740 ENOG4108RMJ sensory transduction regulator HVW55_16750 ENOG4108DBC nitroreductase HVW55_16755 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HVW55_16760 ENOG41090BQ Glutaredoxin HVW55_16765 ENOG4105GWF inner membrane protein YbjM HVW55_16780 ENOG4108RFG Tetr family transcriptional regulator HVW55_16785 ENOG4106UW1 Major Facilitator superfamily HVW55_16790 ENOG4108HCJ Hydrolase HVW55_16800 ENOG4107QF7 multi-drug HVW55_16805 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HVW55_16810 ENOG4107FB0 transcriptional regulator DeoR family HVW55_16815 ENOG4105DZ1 carboxypeptidase HVW55_16820 ENOG4108TGY Glutathione S-transferase HVW55_16825 ENOG4105D8V Glucose sorbosone dehydrogenase HVW55_16830 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HVW55_16850 ENOG41064RH membrane protein YliF HVW55_16855 ENOG4105BZU Histidine kinase HVW55_16870 ENOG4105DEF Extracellular solute-binding protein, family 5 HVW55_16880 ENOG4105D44 asparaginase HVW55_16885 ENOG4105CVM Molybdenum cofactor synthesis domain protein HVW55_16890 ENOG4105D06 uba thif-type nad fad binding protein HVW55_16895 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HVW55_16900 ENOG4105F1A Pyruvate formate-lyase HVW55_16910 ENOG4108HCJ Hydrolase HVW55_16915 ENOG41072TH Protein of unknown function (DUF1479) HVW55_16920 ENOG4105C5H ABC transporter HVW55_16925 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HVW55_16930 ENOG4105F4P )-transporter HVW55_16935 ENOG4105KST dependent repressor HVW55_16945 ENOG4108I6E Sulfatase HVW55_16950 ENOG4108T1M outer membrane protein x HVW55_16960 ENOG4107AQZ Membrane HVW55_16970 ENOG4107R0W ABC transporter HVW55_16975 ENOG4105E5Q amino acid AbC transporter HVW55_16980 ENOG4105CDA abc transporter atp-binding protein HVW55_16985 ENOG4105D8X mechanosensitive ion channel HVW55_16995 ENOG4105ZY9 UPF0379 protein ybiM HVW55_17000 ENOG4108IU3 tonb-dependent siderophore receptor HVW55_17010 ENOG4105KSC Transcriptional regulator, TraR DksA family HVW55_17015 ENOG4105VR4 UPF0379 protein ybiJ HVW55_17020 ENOG4105DG4 malate L-lactate dehydrogenase HVW55_17025 ENOG4108MTB glycosyl transferase family HVW55_17030 ENOG4105DVT helicase HVW55_17045 ENOG4105C1J atp-dependent rna helicase HVW55_17050 ENOG4107MVR Transcriptional regulator HVW55_17060 ENOG4105CJ1 ABC, transporter HVW55_17065 ENOG4107QWP ABC-2 type transporter HVW55_17070 ENOG4107QWP ABC-2 type transporter HVW55_17075 ENOG4105I9U inner membrane protein ybhQ HVW55_17080 ENOG4105X23 Endonuclease Exonuclease phosphatase HVW55_17085 ENOG4105DZQ phospholipase D Transphosphatidylase HVW55_17090 ENOG4107UXM Membrane HVW55_17095 ENOG410733J conserved inner membrane protein HVW55_17100 ENOG4105HFZ Membrane HVW55_17105 ENOG4108ZAF Molybdopterin HVW55_17110 ENOG4105M00 molybdopterin converting factor, subunit 1 HVW55_17120 ENOG4108RIR Molybdenum cofactor biosynthesis protein HVW55_17130 ENOG4105CHW UPF0052 protein HVW55_17140 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HVW55_17145 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HVW55_17160 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HVW55_17165 ENOG4108V1U phospholipid-binding protein HVW55_17170 ENOG4105NBR Pectinesterase HVW55_17175 ENOG4107QM5 aconitate hydratase HVW55_17180 ENOG4107QPK )-transporter HVW55_17185 ENOG4105C7F AcnD-accessory protein PrpF HVW55_17190 ENOG4105F04 LysR family Transcriptional regulator HVW55_17200 ENOG4108K4B hydrolase HVW55_17210 ENOG4105E0C molybdate abc transporter HVW55_17215 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HVW55_17225 ENOG4105F4R Transcriptional regulator mode HVW55_17230 ENOG4105DKW ABC transporter HVW55_17235 ENOG4105CMR udp-glucose 4-epimerase HVW55_17240 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HVW55_17250 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HVW55_17260 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HVW55_17265 ENOG4105JND homeobox protein HVW55_17270 ENOG4105PGM cation diffusion facilitator family transporter HVW55_17275 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HVW55_17280 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) HVW55_17320 ENOG4105UFD tol-pal system protein YbgF HVW55_17325 ENOG4105KCK Peptidoglycan-associated lipoprotein HVW55_17335 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HVW55_17345 ENOG4105E02 MotA TolQ exbB proton channel HVW55_17350 ENOG4107YD3 Thioesterase HVW55_17355 ENOG4105KJB cyd operon protein YbgE HVW55_17365 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HVW55_17370 ENOG4105C4M (Ubiquinol oxidase) subunit I HVW55_17385 ENOG4107WFU Glutamate mutase subunit sigma HVW55_17395 ENOG4105DJI Methylaspartate mutase, E subunit HVW55_17420 ENOG4107GFK fumarate HVW55_17425 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HVW55_17430 ENOG4105ETT transcriptional Regulator, LysR family HVW55_17435 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HVW55_17445 ENOG4105C7S Dehydrogenase HVW55_17450 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HVW55_17455 ENOG4105E33 succinate dehydrogenase HVW55_17460 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HVW55_17465 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HVW55_17470 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HVW55_17480 ENOG4105BZN citrate synthase HVW55_17485 ENOG4106UBK fimbrial-like adhesin protein HVW55_17490 ENOG4106PG1 outer membrane usher protein HVW55_17495 ENOG4108TTM chaperone HVW55_17500 ENOG4108MY7 Fimbrial HVW55_17505 ENOG4108KK1 membrane protein AbrB duplication HVW55_17510 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) HVW55_17520 ENOG4107R7A Allophanate hydrolase subunit 2 HVW55_17525 ENOG4105P4J Allophanate hydrolase, subunit 1 HVW55_17530 ENOG4107QNR UPF0135 protein HVW55_17535 ENOG4105DUX Transporter HVW55_17540 ENOG4105CVP deoxyribo-dipyrimidine photolyase HVW55_17545 ENOG4107SEY Conserved Protein HVW55_17550 ENOG4105XIQ Protein of unknown function (DUF2517) HVW55_17575 ENOG4105C08 Histidine kinase HVW55_17580 ENOG4105EEX Two component transcriptional regulator (Winged helix family HVW55_17590 ENOG4105CXN decarboxylase HVW55_17595 ENOG4105D5Q Arginine ornithine antiporter HVW55_17600 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HVW55_17605 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HVW55_17610 ENOG4105EV9 Alpha Beta Hydrolase HVW55_17615 ENOG4105NNH LexA regulated protein HVW55_17620 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HVW55_17630 ENOG41090R7 Ferric uptake HVW55_17635 ENOG4105GX6 (LipO)protein HVW55_17650 ENOG4105CI1 PTS System HVW55_17660 ENOG4105CE4 GlcNAc 6-P deacetylase HVW55_17665 ENOG4105E2R ROK family HVW55_17670 ENOG4105D4U had-superfamily hydrolase, subfamily iia HVW55_17675 ENOG4105CAQ asparagine synthetase HVW55_17715 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HVW55_17725 ENOG4105C9A Phoh family HVW55_17735 ENOG4108JU5 Magnesium and cobalt efflux protein HVW55_17740 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HVW55_17745 ENOG4107RP9 extracellular solute-binding protein, family 3 HVW55_17750 ENOG4105EAD ABC transporter HVW55_17755 ENOG4105DRP amino acid AbC transporter HVW55_17760 ENOG4105CDA abc transporter atp-binding protein HVW55_17770 ENOG4105F7F Chaperone HVW55_17775 ENOG4105QFC Hsc56 co-chaperone of HscC HVW55_17780 ENOG41069CF Protein of unknown function (DUF1266) HVW55_17785 ENOG4107JFD Sel1 repeat HVW55_17790 ENOG4105QFC Hsc56 co-chaperone of HscC HVW55_17795 ENOG41069CF Protein of unknown function (DUF1266) HVW55_17800 ENOG4105EUU Sel1 domain protein repeat-containing protein HVW55_17805 ENOG4107PAI alpha helical protein HVW55_17820 ENOG4105DJF DNA polymerase III, delta' subunit HVW55_17830 ENOG4108TGR phosphatase HVW55_17835 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HVW55_17845 ENOG4105CJN penicillin-binding protein HVW55_17850 ENOG4105CNI cell division protein FtsW HVW55_17855 ENOG4105K6T rare lipoprotein A HVW55_17860 ENOG4105DZ1 carboxypeptidase HVW55_17875 ENOG41064T2 transcriptional regulator, lysR family HVW55_17885 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HVW55_17905 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HVW55_17910 ENOG4105CEE C4-dicarboxylate transporter HVW55_17915 ENOG4106YYS transcriptional regulatory protein HVW55_17920 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HVW55_17925 ENOG4105DUA (citrate (pro-3S)-lyase ligase HVW55_17935 ENOG4105CI0 Citrate lyase HVW55_17940 ENOG4105CHY citrate lyase, alpha HVW55_17955 ENOG4107QPK )-transporter HVW55_17960 ENOG4105KTS ribonuclease HVW55_17965 ENOG4105NXH GreA GreB family elongation factor HVW55_17970 ENOG4105E2A Dehydrogenase HVW55_17975 ENOG4108U51 Universal stress protein HVW55_17980 ENOG4108JU3 Alkyl hydroperoxide reductase HVW55_17985 ENOG4105D3R alkyl hydroperoxide reductase HVW55_17990 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HVW55_17995 ENOG4105DQS Transcriptional regulator HVW55_18000 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HVW55_18005 ENOG4105GTN ParB Domain Protein Nuclease HVW55_18010 ENOG4105CHM Aminotransferase HVW55_18015 ENOG4107SCQ Iron-containing alcohol dehydrogenase HVW55_18020 ENOG4105VCD cytoplasmic protein HVW55_18095 ENOG4105IM0 capsid protein HVW55_18120 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HVW55_18125 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HVW55_18130 ENOG4105WQI isochorismatase HVW55_18135 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HVW55_18140 ENOG4105E4F Isochorismate synthase HVW55_18145 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HVW55_18155 ENOG4105DQ5 transport system permease protein HVW55_18160 ENOG4105TVJ transport system, permease HVW55_18165 ENOG4105E0A ABC, transporter HVW55_18170 ENOG4108QY5 Ferric enterobactin transport protein HVW55_18175 ENOG4105C0W non-ribosomal peptide synthetase HVW55_18180 ENOG41085A6 mbth domain-containing protein HVW55_18185 ENOG4105E93 esterase HVW55_18190 ENOG4107RNH Outer membrane receptor FepA HVW55_18195 ENOG4108TSE Transferase HVW55_18220 ENOG4105WQ6 Membrane HVW55_18225 ENOG4105MSB protein, conserved in bacteria HVW55_18230 ENOG4108RCM Nitroreductase HVW55_18235 ENOG4105CUY Mechanosensitive ion channel HVW55_18240 ENOG4105C85 amino acid HVW55_18245 ENOG4108IJF Heavy metal efflux pump, CzcA HVW55_18250 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HVW55_18255 ENOG410624V efflux system protein HVW55_18260 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HVW55_18265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HVW55_18270 ENOG4105GR3 Histidine kinase HVW55_18275 ENOG410802X bacteriophage n4 adsorption protein b HVW55_18280 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HVW55_18285 ENOG4105QUW HVW55_18300 ENOG4108Q9V regulatoR HVW55_18305 ENOG4108ZI2 Fimbrial protein HVW55_18310 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HVW55_18315 ENOG4105CW0 outer membrane usher protein HVW55_18320 ENOG4108AF8 Chaperone HVW55_18325 ENOG4108WDE Fimbrial protein HVW55_18335 ENOG4105WQ3 Rna-binding protein HVW55_18340 ENOG4105S2T inner membrane protein YbcI HVW55_18350 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HVW55_18360 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HVW55_18365 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HVW55_18370 ENOG4105C5B carbamate kinase HVW55_18375 ENOG4105G5A Protein of unknown function (DUF2877) HVW55_18380 ENOG4107REC cytoplasmic protein HVW55_18385 ENOG4107R1Q Membrane protein FdrA HVW55_18390 ENOG4105DG4 malate L-lactate dehydrogenase HVW55_18395 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HVW55_18400 ENOG4105S0E allantoin catabolism protein HVW55_18405 ENOG4105BZW Glycerate kinase HVW55_18410 ENOG4105DTE Xanthine uracil vitamin C permease HVW55_18420 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HVW55_18425 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HVW55_18430 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HVW55_18435 ENOG41060W2 glyoxylate carboligase HVW55_18440 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HVW55_18450 ENOG4107653 Transcriptional regulator HVW55_18475 ENOG4105CV6 ABC transporter, permease HVW55_18480 ENOG4108I0Y (ABC) transporter HVW55_18485 ENOG4108UJV acyl-CoA thioesterase i HVW55_18490 ENOG4105E1F short-chain dehydrogenase reductase HVW55_18495 ENOG4107QR8 Thioredoxin HVW55_18500 ENOG4105C4B ABC transporter, permease HVW55_18505 ENOG41083J0 (ABC) transporter HVW55_18510 ENOG4107QX8 SPFH domain, Band 7 family protein HVW55_18515 ENOG4105G5H Membrane HVW55_18540 ENOG4107QZV Type I secretion membrane fusion protein HVW55_18560 ENOG4107RY6 amino acid HVW55_18565 ENOG4105CSV Glutaminase HVW55_18570 ENOG4105C59 p-type ATPase HVW55_18575 ENOG41081XE plasmid maintenance system antidote protein, xre family HVW55_18580 ENOG4105MBR gumn family HVW55_18585 ENOG4108Z66 YbaK ebsC protein HVW55_18590 ENOG4105CGH 5'-nucleotidase HVW55_18595 ENOG4105EU0 Major facilitator Superfamily HVW55_18600 ENOG4105CKD glutathione-regulated potassium-efflux system protein HVW55_18610 ENOG4107RE1 Inosine-guanosine kinase HVW55_18645 ENOG4107QMP dna polymerase iii subunits gamma and tau HVW55_18655 ENOG4105WD1 Membrane HVW55_18660 ENOG4108URS primosomal replication protein n'' HVW55_18665 ENOG4106428 Protein of unknown function (DUF2496) HVW55_18670 ENOG4105EGS Mechanosensitive ion channel HVW55_18675 ENOG4107XI7 Tetr family transcriptional regulator HVW55_18680 ENOG4105C1P efflux transporter, rnd family, mfp subunit HVW55_18685 ENOG4105BZS acriflavin resistance protein HVW55_18690 ENOG4108UKR Biofilm formation regulator YbaJ HVW55_18695 ENOG4105KF5 hemolysin expression-modulating protein HVW55_18700 ENOG4108UW5 maltose o-acetyltransferase HVW55_18705 ENOG4105GSJ Inner membrane protein ylaC HVW55_18710 ENOG41066DG (EAL) domain protein HVW55_18715 ENOG4105KCV RNA signal recognition particle 4.5S RNA HVW55_18725 ENOG41080UX Methyltransferase HVW55_18730 ENOG4108MNP Glycoprotein polysaccharide metabolism HVW55_18735 ENOG4105C29 acyl-CoA thioesterase HVW55_18740 ENOG4105BZU Histidine kinase HVW55_18745 ENOG4108YZA Nitrogen regulatory protein pii HVW55_18750 ENOG4105BZ1 (ABC) transporter HVW55_18755 ENOG4105BZ1 (ABC) transporter HVW55_18760 ENOG4108XM1 transcriptional regulator AsnC family HVW55_18770 ENOG4108NFA extracellular solute-binding protein HVW55_18780 ENOG4108TGP Thioesterase superfamily protein HVW55_18785 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HVW55_18790 ENOG4105EIN peptidylprolyl cis-trans isomerase HVW55_18795 ENOG4105K70 DNA-binding protein HVW55_18800 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HVW55_18820 ENOG4105M85 Bola protein HVW55_18825 ENOG4105IEY (LipO)protein HVW55_18830 ENOG4105EYM Major Facilitator superfamily HVW55_18835 ENOG4105E2S oxidase) subunit II HVW55_18840 ENOG4105BZ9 Cytochrome C oxidase, subunit I HVW55_18845 ENOG4105CCU oxidase (Subunit III) HVW55_18850 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HVW55_18860 ENOG4107RDB Major Facilitator HVW55_18870 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HVW55_18875 ENOG4107S0N DJ-1 family HVW55_18890 ENOG4105CTB Polyprenyl synthetase HVW55_18900 ENOG4105CPC Aldo Keto reductase HVW55_18910 ENOG4108ZAI phosphatidylglycerophosphatase a HVW55_18915 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HVW55_18925 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HVW55_18930 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HVW55_18940 ENOG4108KIC (LipO)protein HVW55_18945 ENOG4105DRB nucleoside-specific channel-forming protein HVW55_18950 ENOG4105N1F Hnh endonuclease HVW55_18960 ENOG4105X54 addiction module antidote protein HVW55_18965 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HVW55_18970 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HVW55_18975 ENOG4105VIE preprotein translocase, subunit YajC HVW55_18990 ENOG4108ZYK Acyl carrier protein phosphodiesterase HVW55_19000 ENOG4107R28 alpha amylase, catalytic region HVW55_19005 ENOG4105C85 amino acid HVW55_19010 ENOG4105CWM branched-chain amino acid transport system II carrier protein HVW55_19015 ENOG4105BZU Histidine kinase HVW55_19020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HVW55_19025 ENOG4107RH8 nuclease SbcCD subunit D HVW55_19030 ENOG4105EYH Exonuclease HVW55_19035 ENOG4105F27 Major Facilitator HVW55_19040 ENOG4105DKQ ROK family HVW55_19065 ENOG4105HBA AroM protein HVW55_19070 ENOG4105SS3 HVW55_19085 ENOG4105II7 pyrroline-5-carboxylate reductase HVW55_19090 ENOG4105BZU Histidine kinase HVW55_19095 ENOG4105VIF phosphate starvation-inducible protein HVW55_19100 ENOG4105G6Z alkaline phosphatase HVW55_19115 ENOG4105CPF Cell wall formation (By similarity) HVW55_19120 ENOG4105UNH Membrane HVW55_19125 ENOG4105FR5 inner membrane protein YaiY HVW55_19130 ENOG4107QS8 (LipO)protein HVW55_19135 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HVW55_19140 ENOG4107R6D beta-lactam binding protein AmpH HVW55_19145 ENOG4108PNB DNA-binding transcriptional regulator HVW55_19155 ENOG4105D52 delta-aminolevulinic acid dehydratase HVW55_19160 ENOG4105E2B Taurine dioxygenase HVW55_19165 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HVW55_19175 ENOG4106FTQ Taurine ABC transporter, periplasmic HVW55_19180 ENOG4108KX4 response regulator HVW55_19185 ENOG4105BZU Histidine kinase HVW55_19190 ENOG4105CXY transporter HVW55_19195 ENOG4105C4Y ABC transporter HVW55_19200 ENOG4107RCV ABC transporter, permease HVW55_19205 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HVW55_19220 ENOG4105C4W S-formylglutathione hydrolase HVW55_19225 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HVW55_19230 ENOG4108SC4 )-transporter HVW55_19250 ENOG4106HB6 Alpha beta hydrolase HVW55_19265 ENOG4108K2P TRANSCRIPTIONal HVW55_19270 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein HVW55_19280 ENOG4105ETE Transcriptional regulator (LacI family HVW55_19290 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HVW55_19295 ENOG4108UW5 maltose o-acetyltransferase HVW55_19300 ENOG4105DJ2 Major Facilitator Superfamily HVW55_19310 ENOG4107B2H carbonic anhydrase HVW55_19315 ENOG4105DND Transcriptional regulator HVW55_19320 ENOG4105DZC cytosine deaminase HVW55_19325 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HVW55_19330 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HVW55_19335 ENOG4105DXD 2-methylcitrate dehydratase HVW55_19340 ENOG4105BZN citrate synthase HVW55_19345 ENOG4105CR4 methylisocitrate lyase HVW55_19350 ENOG4108JU7 Transcriptional regulator HVW55_19355 ENOG4105TDT uncharacterized protein yahO HVW55_19360 ENOG4105E82 cytochrome subunit of dehydrogenase HVW55_19375 ENOG4105DQ4 alcohol dehydrogenase HVW55_19380 ENOG4105CNN ABC, transporter HVW55_19385 ENOG4105CNN ABC, transporter HVW55_19390 ENOG4105C2J ABC transporter HVW55_19395 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HVW55_19405 ENOG4105DZC cytosine deaminase HVW55_19410 ENOG4105C5B carbamate kinase HVW55_19420 ENOG4107REC cytoplasmic protein HVW55_19425 ENOG4107R1Q Membrane protein FdrA HVW55_19430 ENOG4105N16 Protein of unknown function (DUF2877) HVW55_19435 ENOG4107SNB ankyrin repeat protein YahD HVW55_19440 ENOG4105SZ2 membrAne HVW55_19445 ENOG4108NUU Transcriptional regulator HVW55_19450 ENOG4105BZU Histidine kinase HVW55_19460 ENOG4105C94 Transporter HVW55_19480 ENOG4108W9T type 1 fimbriae regulatory protein HVW55_19485 ENOG4105BZU Histidine kinase HVW55_19510 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HVW55_19515 ENOG4107QR9 Iron-sulfur cluster binding protein HVW55_19520 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HVW55_19525 ENOG4108K01 transcriptional regulator HVW55_19530 ENOG4107QN2 dihydrolipoyl dehydrogenase HVW55_19535 ENOG41066GK UPF0379 protein ykgI HVW55_19540 ENOG4108KBJ Inner membrane protein YkgB HVW55_19545 ENOG4105CV8 reductase HVW55_19565 ENOG4107SET aldo keto reductase HVW55_19570 ENOG4105EQ2 LysR family Transcriptional regulator HVW55_19575 ENOG410642W LysR family Transcriptional regulator HVW55_19580 ENOG4105ENX hydrolase HVW55_19585 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HVW55_19625 ENOG4108N3D putative enzyme HVW55_19630 ENOG4106PYX Receptor HVW55_19635 ENOG4108UD7 cell wall organization HVW55_19640 ENOG4105PI0 Ferredoxin HVW55_19645 ENOG4105R3P Inner membrane protein yagU HVW55_19650 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HVW55_19655 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding HVW55_19660 ENOG4105C7W Xanthine dehydrogenase HVW55_19665 ENOG4107XAN XdhC and CoxI family HVW55_19670 ENOG4107RTG Major Facilitator superfamily HVW55_19675 ENOG4105ENX hydrolase HVW55_19680 ENOG4105EQ2 LysR family Transcriptional regulator HVW55_19690 ENOG4105EMU Dehydrogenase HVW55_19710 ENOG4105HVQ Regulatory factor of maltose metabolism HVW55_19830 ENOG4105DFP Integrase HVW55_19850 ENOG4105FCK Membrane HVW55_19860 ENOG4105V1F Fermentation respiration switch protein HVW55_19870 ENOG4105CIN aminoacyl-histidine dipeptidase HVW55_19875 ENOG4108S2Y peptide Chain Release factor HVW55_19885 ENOG4108HYG acetyltransferase HVW55_19890 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HVW55_19905 ENOG4108UK5 Transposase HVW55_19910 ENOG4108YS0 lipoprotein YafL HVW55_19920 ENOG4105VXN addiction module toxin, RelE StbE family HVW55_19925 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HVW55_19930 ENOG4105E7A Glutamine amidotransferase HVW55_19940 ENOG4107QPN acyl-Coa dehydrogenase HVW55_19945 ENOG4108WN0 inhibitor of vertebrate lysozyme HVW55_19950 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HVW55_19960 ENOG410600T transposase HVW55_19985 ENOG4108YXQ IS66 Orf2 family protein HVW55_19990 ENOG4105E5H Transposase HVW55_20000 ENOG4105CS6 Rhs element vgr protein HVW55_20005 ENOG4108WC9 type VI secretion system effector, hcp1 family HVW55_20060 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HVW55_20105 ENOG410600K aminopeptidase HVW55_20115 ENOG4107RZZ dna polymerase iii epsilon subunit HVW55_20125 ENOG4105D1A Methyltransferase HVW55_20130 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) HVW55_20135 ENOG4105E9H Lytic Murein transglycosylase HVW55_20140 ENOG4105F2W methyltransferase HVW55_20150 ENOG4105HEI LysR family (Transcriptional regulator HVW55_20155 ENOG4105CV8 reductase HVW55_20190 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HVW55_20195 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HVW55_20200 ENOG4108UMI ABC transporter, permease HVW55_20205 ENOG4105D01 (LipO)protein HVW55_20210 ENOG4108R8X outer membrane lipoprotein HVW55_20215 ENOG4108R96 Methyltransferase, YaeB family HVW55_20225 ENOG4108UY0 (LipO)protein HVW55_20230 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HVW55_20235 ENOG4108YZN class I peptide chain release factor HVW55_20240 ENOG4108VWS Yaeq family HVW55_20250 ENOG4105M1T rho-binding antiterminator HVW55_20255 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HVW55_20260 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HVW55_20265 ENOG4105CXN decarboxylase HVW55_20275 ENOG4105C0B DNA polymerase III (alpha subunit) HVW55_20300 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HVW55_20305 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HVW55_20315 ENOG4105DZP Membrane-associated zinc metalloprotease HVW55_20320 ENOG4105KNE Phosphatidate cytidylyltransferase HVW55_20325 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HVW55_20330 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HVW55_20355 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HVW55_20375 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HVW55_20380 ENOG4105C0H protease HVW55_20395 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HVW55_20400 ENOG4105EN6 Membrane HVW55_20425 ENOG4105S6R Iron-hydroxamate transporter permease subunit HVW55_20430 ENOG4105J76 Periplasmic binding protein HVW55_20435 ENOG4105E0A ABC, transporter HVW55_20440 ENOG4105E0K tonB-dependent siderophore receptor HVW55_20445 ENOG4105BZ4 penicillin-binding protein HVW55_20450 ENOG4105CQ7 ATP-dependent helicase HVW55_20455 ENOG4107XID 2'-5' rna ligase HVW55_20475 ENOG4105DJ0 Poly(A) Polymerase HVW55_20480 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HVW55_20490 ENOG4108VEV chaperone HVW55_20495 ENOG4105CW0 outer membrane usher protein HVW55_20500 ENOG4108XEY fimbrial-like adhesin protein HVW55_20505 ENOG4105SYG Fimbrial protein HVW55_20535 ENOG4108A32 Transposase HVW55_20545 ENOG4107BJW polysaccharide deacetylase HVW55_20550 ENOG4108YTN IIa component HVW55_20555 ENOG4105E3A (ABC) transporter HVW55_20560 ENOG4105DA5 (ABC) transporter HVW55_20565 ENOG41077A9 carbonic anhydrase HVW55_20570 ENOG4108UGV hypoxanthine phosphoribosyltransferase HVW55_20575 ENOG4105DZG Dehydrogenase HVW55_20580 ENOG4105E3B Multicopper oxidase HVW55_20585 ENOG4108ZRK uncharacterized protein yacC HVW55_20605 ENOG4107QIJ Aconitate hydratase 2 HVW55_20610 ENOG4108NST exported protein HVW55_20615 ENOG4107QN2 dihydrolipoyl dehydrogenase HVW55_20620 ENOG4107QSN dihydrolipoamide acetyltransferase HVW55_20625 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HVW55_20630 ENOG41073TP transcriptional regulator HVW55_20635 ENOG4105C85 amino acid HVW55_20640 ENOG4106A72 regulatory protein AmpE HVW55_20645 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HVW55_20650 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HVW55_20655 ENOG4108ZUW Major pilin subunit HVW55_20660 ENOG4107QHF type ii secretion system protein e HVW55_20665 ENOG4105D7Q type ii secretion system HVW55_20680 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HVW55_20695 ENOG4105M6F mutator MutT protein HVW55_20715 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HVW55_20720 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HVW55_20725 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HVW55_20730 ENOG4105CPF Cell wall formation (By similarity) HVW55_20745 ENOG4105CNI cell division protein FtsW HVW55_20750 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HVW55_20760 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HVW55_20765 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HVW55_20770 ENOG4105CJN penicillin-binding protein HVW55_20775 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HVW55_20790 ENOG4107B7Y DNA-binding transcriptional regulator FruR HVW55_20800 ENOG4108ZP8 Acetolactate synthase small subunit HVW55_20805 ENOG4105C7K acetolactate synthase HVW55_20815 ENOG41064T2 transcriptional regulator, lysR family HVW55_20860 ENOG4105DP9 ABC transporter HVW55_20865 ENOG4106SMU thiamine transporter membrane protein HVW55_20870 ENOG4107T0D ABC, transporter HVW55_20875 ENOG4108KF1 Membrane HVW55_20880 ENOG41063TF transcriptional regulator (AraC HVW55_20885 ENOG4105EF1 ribulokinase HVW55_20895 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HVW55_20900 ENOG4105CQ2 DNA polymerase HVW55_20905 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HVW55_20910 ENOG4105D3G Pseudouridine synthase HVW55_20925 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HVW55_20930 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HVW55_20935 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HVW55_20970 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HVW55_20985 ENOG4105C54 Major Facilitator superfamily HVW55_20990 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HVW55_20995 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HVW55_21030 ENOG4106YT9 Enoyl-CoA hydratase HVW55_21040 ENOG4108XNW Transcriptional activatory protein CaiF HVW55_21045 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HVW55_21050 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HVW55_21070 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HVW55_21080 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HVW55_21085 ENOG4105DTN riboflavin biosynthesis protein ribF HVW55_21090 ENOG410647N response to DNA damage stimulus HVW55_21110 ENOG4108MQF Chaperone HVW55_21115 ENOG4105CW0 outer membrane usher protein HVW55_21125 ENOG41063Z6 transcriptional regulator, lysR family HVW55_21135 ENOG4105WI6 cell killing protein encoded within cryptic prophage HVW55_21155 ENOG4108QUJ UPF0174 protein YaaW HVW55_21160 ENOG4106HK8 GPR1 FUN34 yaaH family protein HVW55_21165 ENOG4108RIR Molybdenum cofactor biosynthesis protein HVW55_21170 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HVW55_21175 ENOG4105BZG amino acid carrier protein HVW55_21185 ENOG41062C6 Protein of unknown function (DUF2502) HVW55_21190 ENOG4105D98 threonine synthase HVW55_21200 ENOG4105CFH Aspartokinase HVW55_21210 ENOG4106FVC RNA methyltransferase HVW55_21215 ENOG410759A HVW55_21220 ENOG41065U4 response regulator HVW55_21225 ENOG4105CT7 inner membrane cred family protein HVW55_21230 ENOG4105EB3 Histidine kinase HVW55_21235 ENOG4105E3W Two component transcriptional regulator (Winged helix family HVW55_21240 ENOG4108RH0 Crea protein HVW55_21245 ENOG4105UEI Transcriptional Regulator AraC Family HVW55_21265 ENOG4107SC1 transglycosylase HVW55_21270 ENOG4105C5H ABC transporter HVW55_21275 ENOG4107RSM transcriptional regulator HVW55_21285 ENOG4105EWI Short-chain dehydrogenase reductase Sdr HVW55_21300 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HVW55_21305 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HVW55_21310 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HVW55_21315 ENOG4105EAC phosphoserine phosphatase HVW55_21320 ENOG41062Z9 Membrane HVW55_21350 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) HVW55_21355 ENOG4105G0K glycine radical enzyme YjjI family HVW55_21360 ENOG41076CZ activating enzyme HVW55_21365 ENOG4105EYA deoxyribonuclease HVW55_21370 ENOG4108NRW Phospholipase, patatin family HVW55_21380 ENOG4105K3G Periplasmic Protein HVW55_21390 ENOG4105PAD Hydrolase HVW55_21395 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HVW55_21400 ENOG4108WPU DNA polymerase III subunit psi HVW55_21405 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) HVW55_21425 ENOG4105YBH Protein of unknown function (DUF1435) HVW55_21430 ENOG4108819 ferric iron reductase HVW55_21435 ENOG4108T94 DNA-binding transcriptional activator BglJ HVW55_21440 ENOG4108N8T regulatoR HVW55_21445 ENOG4105DWK Membrane HVW55_21460 ENOG4106CVF DNA replication protein HVW55_21465 ENOG4105RI1 glycoprotein receptor HVW55_21475 ENOG4105CPQ Dehydrogenase HVW55_21485 ENOG4108I5G Major Facilitator superfamily HVW55_21490 ENOG4105C8Q Methyl-accepting chemotaxis HVW55_21495 ENOG4108V8F Transcriptional regulator, MarR family HVW55_21500 ENOG4105ERH Fumarylacetoacetate hydrolase HVW55_21505 ENOG4105C26 Dehydrogenase HVW55_21510 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HVW55_21540 ENOG4105EFA 4-hydroxyphenylacetate HVW55_21545 ENOG4107UWN reductase HVW55_21550 ENOG4105D22 carbon starvation protein HVW55_21555 ENOG4105VCD cytoplasmic protein HVW55_21560 ENOG4105CKI cobalamin synthesis protein HVW55_21570 ENOG4106DIZ Domain of unknown function (DUF1127) HVW55_21575 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HVW55_21585 ENOG41083G8 Multidrug resistance protein MdtM HVW55_21590 ENOG4106BRA Membrane HVW55_21595 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HVW55_21600 ENOG4105CIZ coA-substrate-specific enzyme activase HVW55_21615 ENOG4108ZK4 sdia-regulated domain-containing protein HVW55_21620 ENOG4105CBP Major Facilitator HVW55_21625 ENOG4105TNG K13735 adhesin invasin HVW55_21635 ENOG41074DU domain protein HVW55_21640 ENOG4108P2H Inner membrane protein YjiG HVW55_21645 ENOG4105DYB Isoaspartyl dipeptidase HVW55_21650 ENOG4107YNJ LysR family Transcriptional regulator HVW55_21670 ENOG4105C6F GntR Family Transcriptional Regulator HVW55_21675 ENOG4105DEI Mannitol dehydrogenase HVW55_21685 ENOG4107EFN gluconate transport system permease 3 HVW55_21690 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HVW55_21695 ENOG4108T65 Fimbrial HVW55_21700 ENOG4108SQA Fimbrial HVW55_21705 ENOG4105CW0 outer membrane usher protein HVW55_21710 ENOG4108NAE Fimbrial chaperone protein HVW55_21715 ENOG4108S54 Fimbrial protein HVW55_21720 ENOG4108RQP Major type 1 subunit fimbrin HVW55_21725 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HVW55_21730 ENOG4108W9T type 1 fimbriae regulatory protein HVW55_21735 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HVW55_21740 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HVW55_21755 ENOG4105C4R Atp-dependent dna helicase HVW55_21760 ENOG4108I5C dEAD DEAH box helicase HVW55_21770 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HVW55_21830 ENOG4105D7A ATP-binding protein HVW55_21835 ENOG4108K5H permease YjgP YjgQ family protein HVW55_21840 ENOG4108M8S permease YjgP YjgQ family protein HVW55_21850 ENOG4105MYG DNA polymerase iii, chi subunit HVW55_21860 ENOG4108M3P Membrane HVW55_21865 ENOG4108MJ3 acetyltransferase HVW55_21870 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HVW55_21885 ENOG4105XEP YhcH YjgK YiaL family protein HVW55_21890 ENOG4108XFH Transcriptional regulator HVW55_21895 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HVW55_21900 ENOG4108UQ8 endoribonuclease L-psp HVW55_21905 ENOG4107C93 pyrBI operon leader peptide HVW55_21920 ENOG4105KME endoribonuclease L-psp HVW55_21925 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HVW55_21935 ENOG4105D4X repressor HVW55_21940 ENOG4105C5Y PTS System HVW55_21945 ENOG4105CG3 alpha amylase, catalytic region HVW55_21950 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HVW55_21955 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HVW55_21965 ENOG4108XVM Cytochrome b(562) HVW55_21970 ENOG4105CMS peptidase U62, modulator of DNA gyrase HVW55_21980 ENOG4105DFU Cell wall formation (By similarity) HVW55_21990 ENOG41062B0 ABC transporter, permease HVW55_21995 ENOG4107R9N ABC transporter HVW55_22000 ENOG4105C2J ABC transporter HVW55_22005 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HVW55_22010 ENOG4105F0N pyrophosphate phospho-hydrolase HVW55_22015 ENOG4105MZG transcriptional modulator of maze toxin, mazf HVW55_22020 ENOG41087RY SpoVT_AbrB HVW55_22025 ENOG4108ZHD aig2 family HVW55_22030 ENOG4105MA0 exported protein HVW55_22035 ENOG4105CFU surface antigen HVW55_22045 ENOG4105C37 (CBS) domain HVW55_22050 ENOG41061GZ Protein of unknown function (DUF1107) HVW55_22055 ENOG4108UUE Transcriptional regulator HVW55_22065 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HVW55_22070 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HVW55_22075 ENOG4105KVH Transcriptional regulator HVW55_22080 ENOG4105ECR NmrA family HVW55_22085 ENOG4105DXC membrane HVW55_22105 ENOG4105C85 amino acid HVW55_22110 ENOG4108V1T peptidylprolyl cis-trans isomerase HVW55_22115 ENOG4105FHY Opacity-associated protein A HVW55_22125 ENOG4105D7V transposase HVW55_22150 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HVW55_22165 ENOG4105KIT UPF0379 protein yjfY HVW55_22190 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HVW55_22195 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HVW55_22210 ENOG4108MXZ Esterase HVW55_22215 ENOG4105WSB biofilm stress and motility protein A HVW55_22220 ENOG4105S17 UPF0379 protein yjfN HVW55_22225 ENOG4105CSU acyl-Coa dehydrogenase HVW55_22230 ENOG4106032 Glutathionylspermidine synthase HVW55_22235 ENOG4108KXT Conserved Protein HVW55_22240 ENOG4105Z6B inner membrane protein yjfl HVW55_22245 ENOG4107VNS Protein of unknown function (DUF2491) HVW55_22250 ENOG4108P9J Phage shock protein A HVW55_22255 ENOG4105FUX Conserved Protein HVW55_22260 ENOG4105CTX dehydratase HVW55_22265 ENOG4105CSP Major Facilitator Superfamily HVW55_22270 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HVW55_22275 ENOG4107HP6 Transcriptional regulator HVW55_22280 ENOG4105C2N RNA methyltransferase TrmH family group 3 HVW55_22285 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HVW55_22305 ENOG4105EPW hflc protein HVW55_22310 ENOG4107QJR hflk protein HVW55_22315 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HVW55_22335 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HVW55_22340 ENOG4105K8N protein family UPF0079, ATPase HVW55_22345 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HVW55_22390 ENOG4105EGS Mechanosensitive ion channel HVW55_22395 ENOG4107SC7 Inner membrane transporter yjeM HVW55_22405 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HVW55_22410 ENOG4105E33 succinate dehydrogenase HVW55_22425 ENOG41066YJ Beta-lactamase HVW55_22430 ENOG4105QNF Outer membrane lipoprotein HVW55_22435 ENOG4105KPY Small multidrug resistance protein HVW55_22440 ENOG4106BSU Entericidin B HVW55_22445 ENOG4107PEH Entericidin EcnA/B family HVW55_22455 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HVW55_22460 ENOG4105MTB Uncharacterized protein YjeJ HVW55_22465 ENOG4108ZVF (LipO)protein HVW55_22480 ENOG4105DVH amino acid HVW55_22485 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HVW55_22490 ENOG4108IJ0 Aspartate ammonia-lyase HVW55_22495 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HVW55_22510 ENOG4108SIC Transcriptional regulator HVW55_22520 ENOG4108M3R transcriptional activator CadC HVW55_22525 ENOG4105D5Q Arginine ornithine antiporter HVW55_22530 ENOG4105CXN decarboxylase HVW55_22535 ENOG4105DUX Transporter HVW55_22540 ENOG4105CRK lysyL-tRNA synthetase HVW55_22555 ENOG410830R acetyltransferase HVW55_22560 ENOG4105VR1 Pfam:DUF1271 HVW55_22565 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HVW55_22570 ENOG4108MRH transcriptional regulatory protein HVW55_22575 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HVW55_22580 ENOG4107GFK fumarate HVW55_22585 ENOG4108R5S membrane HVW55_22590 ENOG4105CT4 transporter HVW55_22595 ENOG4105F8D glycoside hydrolase family 4 HVW55_22600 ENOG4108K2B transcriptional regulator HVW55_22605 ENOG4105CXN decarboxylase HVW55_22610 ENOG4106ZGR Transcriptional regulator HVW55_22615 ENOG4105D5Q Arginine ornithine antiporter HVW55_22620 ENOG4105DIJ Phosphoethanolamine transferase HVW55_22625 ENOG4105XJC Two component transcriptional regulator (Winged helix family HVW55_22630 ENOG4105ECM Sensor protein basS pmrB HVW55_22640 ENOG4105CSH Transporter HVW55_22645 ENOG4108YIV HVW55_22650 ENOG4108F5E vimentin HVW55_22655 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HVW55_22660 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HVW55_22665 ENOG4105D5T phosphonate abc transporter HVW55_22670 ENOG4105EHI Phosphonate ABC transporter, periplasmic HVW55_22680 ENOG4107RJJ Transcriptional regulator HVW55_22685 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HVW55_22690 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HVW55_22695 ENOG4105EKV Phosphonate metabolism protein HVW55_22700 ENOG4105FT8 Phosphonate metabolism HVW55_22705 ENOG4105ENV phosphonate C-P lyase system protein PhnK HVW55_22710 ENOG4105HRV phosphonate c-p lyase system protein phnl HVW55_22715 ENOG4105FD8 phosphonate metabolism protein PhnM HVW55_22720 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) HVW55_22725 ENOG410849A acetyltransferase, (GNAT) family HVW55_22730 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HVW55_22750 ENOG4105C2J ABC transporter HVW55_22755 ENOG4105CNN ABC, transporter HVW55_22760 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HVW55_22770 ENOG4105D2N Aldolase HVW55_22785 ENOG4105EUZ Beta-lactamase domain protein HVW55_22795 ENOG4105J12 Multidrug resistance protein mdtN HVW55_22800 ENOG4108MI0 Resistance protein HVW55_22815 ENOG41082ND Uncharacterized protein yjcO HVW55_22820 ENOG4105CK2 sodium dicarboxylate symporter HVW55_22825 ENOG4108W0S formate-dependent nitrite reductase complex HVW55_22835 ENOG4108QKW cytochrome c-type biogenesis protein HVW55_22840 ENOG4105DVI reductase, NrfD HVW55_22845 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HVW55_22850 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HVW55_22860 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HVW55_22865 ENOG41062QD Membrane HVW55_22880 ENOG4105EEQ Na H antiporter HVW55_22885 ENOG4105C7N Xanthine uracil vitamin C permease HVW55_22890 ENOG4108Z4X TRANSCRIPTIONal HVW55_22895 ENOG4108W3Q Transcriptional regulator HVW55_22900 ENOG4108M8H domain protein HVW55_22905 ENOG4105PMV Membrane HVW55_22910 ENOG4105VNT transposase (IS4 family) protein HVW55_22915 ENOG4108UUM single-stranded DNA-binding protein HVW55_22920 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HVW55_22925 ENOG4105MSB protein, conserved in bacteria HVW55_22930 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HVW55_22935 ENOG4105F0S class B acid phosphatase HVW55_22945 ENOG4105CGF Aromatic amino acid aminotransferase HVW55_22950 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HVW55_22955 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HVW55_22960 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HVW55_22965 ENOG4105CDU Replicative dna helicase HVW55_22970 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HVW55_22975 ENOG4105P4Z Phage shock protein G HVW55_22980 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HVW55_22990 ENOG4105MYN Zinc uptake regulation protein HVW55_22995 ENOG4105VDW Csbd family HVW55_23000 ENOG4107R73 Mate efflux family protein HVW55_23010 ENOG41080IJ Diacylglycerol kinase HVW55_23035 ENOG4107W52 maltose operon periplasmic protein HVW55_23045 ENOG4108IJ9 (ABC) transporter HVW55_23050 ENOG4107FKK extracellular solute-binding protein family 1 HVW55_23055 ENOG4105D56 permease protein HVW55_23060 ENOG4105EG2 ABC transporter, permease HVW55_23065 ENOG4107QNK )-transporter HVW55_23085 ENOG4105E3R (LipO)protein HVW55_23090 ENOG4108Q9C Periplasmic Protein HVW55_23095 ENOG4108MDC (LipO)protein HVW55_23105 ENOG4107QP8 phosphohexose isomerase HVW55_23110 ENOG4105CFH Aspartokinase HVW55_23120 ENOG410756H nucleotidyltransferase HVW55_23130 ENOG4108ZR5 Conserved Protein HVW55_23135 ENOG4105FE9 pseudouridine synthase HVW55_23140 ENOG4105DKT Transcriptional regulator HVW55_23145 ENOG4105CHR reductase HVW55_23150 ENOG4108XCU pts system HVW55_23155 ENOG4105KPI PTS system sorbose subfamily IIB component HVW55_23160 ENOG4105ETZ PTS System HVW55_23165 ENOG4105F3R pts system mannose fructose sorbose family iid HVW55_23170 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HVW55_23180 ENOG4105EAM Na Pi-cotransporter HVW55_23185 ENOG4105C3R Methionine synthase HVW55_23190 ENOG41069M3 Transcriptional regulator HVW55_23205 ENOG4108I9X Isocitrate lyase HVW55_23210 ENOG4107QP3 malate synthase g HVW55_23220 ENOG4105K5X acetyltransferase HVW55_23250 ENOG4105C12 Phosphoribosylglycinamide synthetase HVW55_23255 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HVW55_23260 ENOG4105BZU Histidine kinase HVW55_23265 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HVW55_23270 ENOG4108T8B Protein of unknown function (DUF1481) HVW55_23280 ENOG4105R2J Conserved Protein HVW55_23305 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) HVW55_23315 ENOG4105D06 uba thif-type nad fad binding protein HVW55_23320 ENOG4105WHD thiamine biosynthesis protein ThiS HVW55_23325 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) HVW55_23330 ENOG4105D41 biosynthesis protein thiH HVW55_23335 ENOG410645W Thiamin biosynthesis protein ThiH HVW55_23340 ENOG410645W Thiamin biosynthesis protein ThiH HVW55_23375 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HVW55_23380 ENOG4105PM1 preprotein translocase subunit SecE HVW55_23415 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HVW55_23420 ENOG4105D4A Cell wall formation (By similarity) HVW55_23450 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) HVW55_23460 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) HVW55_23465 ENOG4108Y73 Membrane HVW55_23470 ENOG4105EJ2 Transcriptional regulator HVW55_23480 ENOG4105CH2 amidohydrolase HVW55_23490 ENOG4105C5Q Transcriptional regulator HVW55_23505 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HVW55_23520 ENOG4105DIJ Phosphoethanolamine transferase HVW55_23525 ENOG4106R3P AraC family transcriptional regulator HVW55_23530 ENOG4108XCZ PTS System HVW55_23535 ENOG4108AHH pyruvate formate lyase II activase HVW55_23545 ENOG4108YRF PTS System HVW55_23550 ENOG4105DM4 PTS System HVW55_23555 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HVW55_23560 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HVW55_23565 ENOG4105DCT glycerol dehydrogenase HVW55_23570 ENOG4108XC3 NADH ubiquinone oxidoreductase HVW55_23575 ENOG4108Q5Y Membrane HVW55_23585 ENOG4105SYT Methylenetetrahydrofolate reductase HVW55_23595 ENOG4105CFH Aspartokinase HVW55_23600 ENOG4105C28 cystathionine HVW55_23610 ENOG4107S01 Repressor protein MetJ HVW55_23620 ENOG4105C25 Primosomal protein n' HVW55_23625 ENOG4105ETE Transcriptional regulator (LacI family HVW55_23630 ENOG41063M6 Cell Division Protein HVW55_23645 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HVW55_23670 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HVW55_23680 ENOG4105CBT Fructose-1,6-bisphosphatase HVW55_23685 ENOG4105DP0 ferredoxin-NADP reductase HVW55_23695 ENOG41065TG regulatoR HVW55_23700 ENOG4108VTS Membrane HVW55_23705 ENOG4105EBK exported protein HVW55_23720 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HVW55_23735 ENOG4105FMW periplasmic HVW55_23740 ENOG4105E3W Two component transcriptional regulator (Winged helix family HVW55_23745 ENOG4105E0F Histidine kinase HVW55_23750 ENOG4108RPX mosc domain containing protein HVW55_23760 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HVW55_23770 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) HVW55_23780 ENOG4105DET Rhamnulokinase HVW55_23790 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) HVW55_23805 ENOG41064BA PTS system, fructose-specific, IIA component HVW55_23810 ENOG4105DM4 PTS System HVW55_23815 ENOG4105CN9 Peptidase m42 family protein HVW55_23820 ENOG4106C3V frv operon regulatory protein HVW55_23825 ENOG4108V87 frv operon regulatory protein HVW55_23840 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HVW55_23845 ENOG4108MG3 formate dehydrogenase HVW55_23855 ENOG41068KX affects formate dehydrogenase-N HVW55_23870 ENOG4105SUU thioesterase domain HVW55_23885 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HVW55_23895 ENOG4105R9B Major Facilitator HVW55_23900 ENOG4108KHF Resistance protein HVW55_23905 ENOG4108K85 Transcriptional regulator HVW55_23910 ENOG4105CI3 gtp-binding protein typa HVW55_23915 ENOG4105C5F glutamine synthetase HVW55_23920 ENOG4105CUX Signal transduction histidine kinase HVW55_23925 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HVW55_23930 ENOG4106FIY HVW55_23935 ENOG4105D4P Coproporphyrinogen iii oxidase HVW55_23940 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) HVW55_23950 ENOG4105C2M dna polymerase I HVW55_23955 ENOG4106HNH Acyl-transferase HVW55_23965 ENOG4108Z33 Thiol disulfide Interchange Protein HVW55_23970 ENOG4105E27 serine threonine protein kinase HVW55_23975 ENOG4105PC1 Conserved Protein HVW55_23980 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HVW55_23985 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HVW55_24010 ENOG4108RR8 protoporphyrinogen oxidase HVW55_24015 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HVW55_24020 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HVW55_24040 ENOG4108EX3 reductase HVW55_24045 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HVW55_24050 ENOG4105MDZ Transcriptional activator rfaH HVW55_24055 ENOG4105F8V Hydrolase, tatD family HVW55_24060 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HVW55_24065 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HVW55_24070 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HVW55_24080 ENOG4105JC1 sterol-binding domain protein HVW55_24090 ENOG4105CGY Dna recombination protein HVW55_24095 ENOG4108I5U Uridine phosphorylase HVW55_24100 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HVW55_24110 ENOG4105DZ2 Transcriptional regulator HVW55_24115 ENOG4105EMK carboxylate amino acid amine transporter HVW55_24120 ENOG4105DQF Hydrolase HVW55_24125 ENOG4108EUD Lysophospholipase HVW55_24130 ENOG410829K Lysine exporter protein (Lyse ygga) HVW55_24135 ENOG4105CCF Lysine exporter protein (Lyse ygga) HVW55_24140 ENOG4105C9U ATP-dependent DNA helicase RecQ HVW55_24145 ENOG4105HDD phospholipase HVW55_24150 ENOG4108VUY thioesterase Superfamily protein HVW55_24155 ENOG4105FR1 rard protein HVW55_24165 ENOG4107QUT magnesium and cobalt transport protein CorA HVW55_24180 ENOG4107QUT magnesium and cobalt transport protein CorA HVW55_24185 ENOG4108T58 Mg2 transport protein CorA HVW55_24190 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HVW55_24195 ENOG4105C4R Atp-dependent dna helicase HVW55_24210 ENOG4105CT0 Protein of unknown function, DUF484 HVW55_24220 ENOG4105S7Z (LipO)protein HVW55_24235 ENOG4107T0K Adenylate cyclase HVW55_24240 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) HVW55_24245 ENOG41076E6 Uroporphyrinogen-III Synthase HVW55_24250 ENOG4105ECF c-methyltransferase HVW55_24255 ENOG410601J HemY protein HVW55_24260 ENOG4105ENH Sulfatase HVW55_24265 ENOG4105C4X radical SAM domain protein HVW55_24290 ENOG4105C85 amino acid HVW55_24305 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) HVW55_24310 ENOG4105EGZ biosynthesis protein HVW55_24315 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HVW55_24320 ENOG4108WJ1 acetyltransferase HVW55_24325 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HVW55_24330 ENOG4105C1B dTDP-glucose 4-6-dehydratase HVW55_24335 ENOG4107QQG Dehydrogenase HVW55_24340 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HVW55_24345 ENOG4105SFE lipopolysaccharide biosynthesis protein HVW55_24350 ENOG4105ESV Glycosyl transferase, family 4 HVW55_24355 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HVW55_24380 ENOG4105C4R Atp-dependent dna helicase HVW55_24390 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HVW55_24400 ENOG4105EMY transcriptional regulator HVW55_24405 ENOG4105C7B Threonine dehydratase HVW55_24415 ENOG4105CM2 brancheD-chain amino acid aminotransferase HVW55_24420 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HVW55_24440 ENOG4105C0P Mg chelatase subunit ChlI HVW55_24445 ENOG4108WFC UPF0438 protein yifE HVW55_24485 ENOG4107EJG GntR family transcriptional regulator HVW55_24490 ENOG4105C0R drug resistance transporter emrb qaca subfamily HVW55_24495 ENOG4105ETE Transcriptional regulator (LacI family HVW55_24500 ENOG4108RVA ribokinase HVW55_24505 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HVW55_24510 ENOG4105CNN ABC, transporter HVW55_24515 ENOG4105C2J ABC transporter HVW55_24545 ENOG4108VVK transcriptional Regulator, AsnC HVW55_24550 ENOG4105QTB Flavodoxin HVW55_24565 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HVW55_24615 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HVW55_24625 ENOG4108NAE Fimbrial chaperone protein HVW55_24630 ENOG4105CW0 outer membrane usher protein HVW55_24640 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HVW55_24645 ENOG4105C8U phosphate abc transporter HVW55_24650 ENOG4105E2Z phosphate ABC transporter (Permease HVW55_24655 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HVW55_24660 ENOG4108UTW Plays a role in the regulation of phosphate uptake HVW55_24665 ENOG4105CID antiterminator HVW55_24670 ENOG4105C5Y PTS System HVW55_24675 ENOG4105CS2 ec 3.2.1.21 HVW55_24685 ENOG4105DYC esterase HVW55_24690 ENOG4107VKM 6-phosphogluconolactonase HVW55_24710 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HVW55_24715 ENOG4105C7N Xanthine uracil vitamin C permease HVW55_24720 ENOG4108YYH Nadph-dependent fmn reductase HVW55_24725 ENOG4105E8Q phosphopantetheinyl transferase HVW55_24740 ENOG4108P6C Tryptophan transporter of low affinity HVW55_24765 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins HVW55_24780 ENOG4105VG0 50S ribosomal protein l34 HVW55_24790 ENOG4106JVB Replication Protein HVW55_24935 ENOG4107R1I NAD-dependent malic enzyme HVW55_24965 ENOG4106CQM replication HVW55_24975 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HVW55_24990 ENOG4105KK6 nuclease HVW55_25000 ENOG4107CBI conjugal transfer fertility inhibition protein HVW55_25005 ENOG4107U2T alpha beta HVW55_25025 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HVW55_25270 ENOG41073YN Protein of unknown function (DUF1380) HVW55_25345 ENOG4105E5H Transposase HVW55_25350 ENOG4108YXQ IS66 Orf2 family protein