locus-tag	class	description
HVW55_00010	COG0592	DNA-directed DNA polymerase activity
HVW55_00020	COG0187	DNA topoisomerase II activity
HVW55_00025	COG3753	Protein conserved in bacteria
HVW55_00030	COG0561	phosphatase activity
HVW55_00045	COG0823	Involved in the tonB-independent uptake of proteins
HVW55_00050	COG5645	(Lipo)protein
HVW55_00070	COG2188	Transcriptional regulator
HVW55_00085	COG2207	Transcriptional regulator
HVW55_00090	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVW55_00095	COG3119	arylsulfatase activity
HVW55_00105	COG2149	membrane
HVW55_00115	COG0641	radical SAM
HVW55_00120	COG2814	Major facilitator Superfamily
HVW55_00135	COG0028	Belongs to the TPP enzyme family
HVW55_00140	COG0440	acetolactate synthase activity
HVW55_00155	COG2197	response regulator
HVW55_00160	COG3851	Histidine kinase
HVW55_00165	COG2271	Major facilitator Superfamily
HVW55_00170	COG2271	Major facilitator Superfamily
HVW55_00185	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVW55_00190	COG2723	6-phospho-beta-galactosidase activity
HVW55_00195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVW55_00205	COG1609	Transcriptional regulator
HVW55_00220	COG2252	PERMEase
HVW55_00245	COG4932	domain protein
HVW55_00245	COG1388	LysM domain
HVW55_00245	COG2373	Large extracellular alpha-helical protein
HVW55_00275	COG0457	Tetratricopeptide repeat
HVW55_00285	COG1464	Belongs to the NlpA lipoprotein family
HVW55_00290	COG0697	spore germination
HVW55_00295	COG2814	Major facilitator Superfamily
HVW55_00355	COG0582	viral genome integration into host DNA
HVW55_00365	COG2211	Major facilitator Superfamily
HVW55_00370	COG1501	Belongs to the glycosyl hydrolase 31 family
HVW55_00375	COG2982	Protein involved in outer membrane biogenesis
HVW55_00380	COG2233	PERMEase
HVW55_00385	COG0786	glutamate:sodium symporter activity
HVW55_00390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HVW55_00395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVW55_00400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVW55_00410	COG0194	GDP metabolic process
HVW55_00420	COG2860	membrane
HVW55_00430	COG1561	YicC-like family, N-terminal region
HVW55_00455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HVW55_00485	COG1519	Transferase
HVW55_00490	COG0859	PFAM glycosyl transferase family 9
HVW55_00495	COG0438	transferase activity, transferring glycosyl groups
HVW55_00500	COG0515	serine threonine protein kinase
HVW55_00510	COG0438	transferase activity, transferring glycosyl groups
HVW55_00515	COG1442	glycosyl transferase family 8
HVW55_00520	COG1442	glycosyl transferase family 8
HVW55_00525	COG3642	lipopolysaccharide core region biosynthetic process
HVW55_00535	COG0859	PFAM glycosyl transferase family 9
HVW55_00540	COG3307	-O-antigen
HVW55_00545	COG0859	PFAM glycosyl transferase family 9
HVW55_00550	COG0859	PFAM glycosyl transferase family 9
HVW55_00560	COG0156	8-amino-7-oxononanoate synthase activity
HVW55_00570	COG1216	Glycosyl transferase, family 2
HVW55_00575	COG2861	carbohydrate metabolic process
HVW55_00580	COG4942	peptidase
HVW55_00590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVW55_00595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVW55_00610	COG1045	serine acetyltransferase
HVW55_00615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HVW55_00625	COG2186	Transcriptional regulator
HVW55_00630	COG1620	l-lactate permease
HVW55_00635	COG5295	Hep Hag repeat protein
HVW55_00655	COG3722	fumarate hydratase activity
HVW55_00665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_00665	COG2213	PTS system mannitol-specific
HVW55_00675	COG1566	PFAM secretion protein HlyD family protein
HVW55_00680	COG0625	glutathione transferase activity
HVW55_00690	COG3276	selenocysteine insertion sequence binding
HVW55_00695	COG1454	alcohol dehydrogenase
HVW55_00700	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_00715	COG1566	PFAM secretion protein HlyD family protein
HVW55_00720	COG0583	DNA-binding transcription factor activity
HVW55_00725	COG3713	MltA-interacting MipA family protein
HVW55_00735	COG2211	Major facilitator Superfamily
HVW55_00745	COG1414	Transcriptional regulator
HVW55_00750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_00755	COG3977	Valine--pyruvate aminotransferase
HVW55_00760	COG0366	Alpha amylase catalytic
HVW55_00765	COG2992	FlgJ-related protein
HVW55_00770	COG1609	Transcriptional regulator
HVW55_00770	COG2207	Transcriptional regulator
HVW55_00775	COG4214	carbohydrate transport
HVW55_00785	COG4213	ABC transporter substrate-binding protein
HVW55_00795	COG1070	Carbohydrate kinase
HVW55_00800	COG4682	membrane
HVW55_00810	COG3274	enterobacterial common antigen metabolic process
HVW55_00835	COG1278	Cold shock
HVW55_00840	COG2944	sequence-specific DNA binding
HVW55_00855	COG2885	chlorophyll binding
HVW55_00860	COG0243	molybdopterin cofactor binding
HVW55_00865	COG0456	acetyltransferase
HVW55_00870	COG2818	Glycosylase
HVW55_00875	COG5571	outer membrane autotransporter
HVW55_00880	COG2223	nitrite transmembrane transporter activity
HVW55_00885	COG3539	Fimbrial protein
HVW55_00890	COG3121	Chaperone
HVW55_00900	COG3539	Fimbrial protein
HVW55_00905	COG3539	Fimbrial protein
HVW55_00910	COG2194	sulfuric ester hydrolase activity
HVW55_00920	COG0747	negative chemotaxis
HVW55_00925	COG0601	transmembrane transport
HVW55_00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVW55_00935	COG0444	Belongs to the ABC transporter superfamily
HVW55_00940	COG4608	Belongs to the ABC transporter superfamily
HVW55_00945	COG0814	amino acid
HVW55_00960	COG2194	sulfuric ester hydrolase activity
HVW55_00985	COG1215	transferase activity, transferring glycosyl groups
HVW55_00990	COG1215	transferase activity, transferring glycosyl groups
HVW55_00995	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HVW55_01000	COG0457	Tetratricopeptide repeat
HVW55_01000	COG3118	belongs to the thioredoxin family
HVW55_01005	COG2199	diguanylate cyclase activity
HVW55_01005	COG2200	EAL domain
HVW55_01015	COG0612	Peptidase, M16
HVW55_01025	COG2200	EAL domain
HVW55_01030	COG2982	Protein involved in outer membrane biogenesis
HVW55_01035	COG0477	Major facilitator Superfamily
HVW55_01040	COG1295	ribonuclease BN
HVW55_01045	COG0583	DNA-binding transcription factor activity
HVW55_01050	COG2197	response regulator
HVW55_01060	COG1858	cytochrome C peroxidase
HVW55_01065	COG0076	glutamate decarboxylase activity
HVW55_01075	COG2207	Transcriptional regulator
HVW55_01080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_01085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_01095	COG2771	luxR family
HVW55_01100	COG3247	response to pH
HVW55_01115	COG1285	pathogenesis
HVW55_01125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_01135	COG3721	Heme iron utilization protein
HVW55_01145	COG4558	Periplasmic binding protein
HVW55_01155	COG4771	TonB-dependent receptor
HVW55_01160	COG3720	iron ion transport
HVW55_01165	COG2197	response regulator
HVW55_01170	COG3065	identical protein binding
HVW55_01180	COG1393	Belongs to the ArsC family
HVW55_01195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVW55_01200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HVW55_01205	COG0339	signal peptide processing
HVW55_01215	COG3104	oligopeptide transport
HVW55_01220	COG0589	response to stress
HVW55_01230	COG0306	phosphate transporter
HVW55_01235	COG2081	HI0933 family
HVW55_01255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_01260	COG1129	ABC transporter
HVW55_01260	COG0842	Transport permease protein
HVW55_01265	COG0842	Transport permease protein
HVW55_01280	COG0191	fructose-bisphosphate aldolase activity
HVW55_01295	COG3775	system Galactitol-specific IIC component
HVW55_01300	COG3414	Phosphotransferase system galactitol-specific IIB component
HVW55_01310	COG2188	Transcriptional regulator
HVW55_01325	COG0444	Belongs to the ABC transporter superfamily
HVW55_01330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVW55_01335	COG0601	transmembrane transport
HVW55_01340	COG0747	negative chemotaxis
HVW55_01345	COG2091	lysine biosynthetic process via aminoadipic acid
HVW55_01350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVW55_01355	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_01365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVW55_01390	COG1216	Glycosyl transferase, family 2
HVW55_01410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HVW55_01420	COG0204	Acyl-transferase
HVW55_01440	COG0628	permease
HVW55_01455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HVW55_01475	COG3714	YhhN family
HVW55_01485	COG3776	membrane
HVW55_01490	COG0742	ribosomal rna small subunit methyltransferase
HVW55_01495	COG0552	protein localization to endoplasmic reticulum
HVW55_01500	COG2884	Cell division ATP-binding protein ftsE
HVW55_01505	COG2177	Part of the ABC transporter FtsEX involved in
HVW55_01510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVW55_01515	COG0683	leucine binding
HVW55_01530	COG0456	acetyltransferase
HVW55_01535	COG0683	leucine binding
HVW55_01540	COG0559	Belongs to the binding-protein-dependent transport system permease family
HVW55_01545	COG4177	L-phenylalanine transmembrane transporter activity
HVW55_01550	COG0411	ABC transporter
HVW55_01555	COG0410	ABC transporter
HVW55_01565	COG1653	transport
HVW55_01570	COG1175	transmembrane transport
HVW55_01580	COG3842	ATPase activity
HVW55_01585	COG0584	glycerophosphoryl diester phosphodiesterase
HVW55_01595	COG0405	Gamma-glutamyltransferase
HVW55_01615	COG3157	Type VI secretion system effector, Hcp
HVW55_01620	COG1247	-acetyltransferase
HVW55_01625	COG0673	inositol 2-dehydrogenase activity
HVW55_01630	COG1741	Belongs to the pirin family
HVW55_01635	COG1609	Transcriptional regulator
HVW55_01640	COG3265	gluconokinase activity
HVW55_01645	COG2610	gluconate transmembrane transporter activity
HVW55_01650	COG0514	ATP-dependent DNA helicase (RecQ)
HVW55_01660	COG2095	MarC family integral membrane protein
HVW55_01665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVW55_01670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HVW55_01690	COG0058	SHG alpha-glucan phosphorylase activity
HVW55_01695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HVW55_01705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVW55_01720	COG1349	DNA-binding transcription factor activity
HVW55_01725	COG4650	regulator
HVW55_01730	COG1690	Belongs to the RtcB family
HVW55_01755	COG0058	SHG alpha-glucan phosphorylase activity
HVW55_01760	COG1640	4-alpha-glucanotransferase
HVW55_01765	COG2610	gluconate transmembrane transporter activity
HVW55_01775	COG1040	competence protein
HVW55_01795	COG5464	transposase or invertase
HVW55_01805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HVW55_01810	COG1918	ferrous iron import across plasma membrane
HVW55_01815	COG2183	response to ionizing radiation
HVW55_01820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVW55_01825	COG0745	RESPONSE REGULATOR receiver
HVW55_01830	COG2205	protein histidine kinase activity
HVW55_01840	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HVW55_01850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HVW55_01855	COG1011	Hydrolase
HVW55_01865	COG0494	nUDIX hydrolase
HVW55_01870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HVW55_01875	COG4972	Pilus assembly protein
HVW55_01880	COG3166	PFAM Fimbrial assembly family protein
HVW55_01895	COG4796	Type ii and iii secretion system protein
HVW55_01910	COG3266	domain, Protein
HVW55_01915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HVW55_01920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HVW55_01930	COG0180	Tryptophanyl-tRNA synthetase
HVW55_01935	COG2188	Transcriptional regulator
HVW55_01945	COG3457	Alanine racemase
HVW55_01950	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HVW55_01955	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HVW55_01970	COG0626	cystathionine gamma-synthase activity
HVW55_01985	COG2116	formate transmembrane transporter activity
HVW55_01990	COG2146	nitrite reductase [NAD(P)H] activity
HVW55_01995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HVW55_02005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HVW55_02015	COG2184	nucleotidyltransferase activity
HVW55_02020	COG0512	Glutamine amidotransferase of anthranilate synthase
HVW55_02025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HVW55_02030	COG1289	transmembrane transporter activity
HVW55_02035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVW55_02040	COG1765	OsmC-like protein
HVW55_02045	COG3954	Phosphoribulokinase
HVW55_02055	COG0429	hydrolase of the alpha beta-hydrolase fold
HVW55_02060	COG0488	(ABC) transporter
HVW55_02075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HVW55_02080	COG1047	Peptidyl-prolyl cis-trans
HVW55_02090	COG0545	Peptidyl-prolyl cis-trans isomerase
HVW55_02095	COG2964	Protein conserved in bacteria
HVW55_02165	COG0089	rRNA binding
HVW55_02255	COG0201	protein transport
HVW55_02295	COG0789	Transcriptional regulator
HVW55_02300	COG3036	rescue of stalled ribosome
HVW55_02310	COG0569	domain protein
HVW55_02330	COG0758	DNA mediated transformation
HVW55_02340	COG0551	DNA topoisomerase type I activity
HVW55_02360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVW55_02400	COG1126	abc transporter atp-binding protein
HVW55_02405	COG0765	amino acid transport
HVW55_02410	COG4597	amino acid ABC transporter
HVW55_02415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_02425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_02430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_02435	COG1309	transcriptional regulator
HVW55_02445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HVW55_02455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVW55_02465	COG4145	pantothenate transmembrane transporter activity
HVW55_02470	COG3924	membrane
HVW55_02475	COG0439	Biotin carboxylase
HVW55_02480	COG0511	ligase activity, forming carbon-carbon bonds
HVW55_02490	COG0604	alcohol dehydrogenase
HVW55_02495	COG2199	diguanylate cyclase activity
HVW55_02495	COG2200	EAL domain
HVW55_02500	COG1077	Cell shape determining protein MreB Mrl
HVW55_02505	COG1792	Involved in formation and maintenance of cell shape
HVW55_02510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HVW55_02520	COG1530	ribonuclease E activity
HVW55_02525	COG3164	Protein of unknown function
HVW55_02530	COG0312	modulator of DNA gyrase
HVW55_02535	COG0583	DNA-binding transcription factor activity
HVW55_02555	COG2732	(Barnase) inhibitor
HVW55_02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVW55_02580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVW55_02585	COG3105	Protein conserved in bacteria
HVW55_02590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HVW55_02605	COG0625	glutathione transferase activity
HVW55_02610	COG2969	positive regulation of protein catabolic process
HVW55_02615	COG3069	C4-dicarboxylate transmembrane transporter activity
HVW55_02645	COG2731	YhcH YjgK YiaL family protein
HVW55_02650	COG4804	nuclease activity
HVW55_02655	COG0493	'glutamate synthase
HVW55_02660	COG0070	glutamate synthase
HVW55_02660	COG0067	glutamate synthase
HVW55_02660	COG0069	glutamate synthase activity
HVW55_02665	COG1242	4 iron, 4 sulfur cluster binding
HVW55_02670	COG5002	protein histidine kinase activity
HVW55_02670	COG2198	Histidine kinase
HVW55_02670	COG0784	Response regulator, receiver
HVW55_02675	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HVW55_02685	COG0515	serine threonine protein kinase
HVW55_02690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_02705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVW55_02710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HVW55_02715	COG1137	ATPase activity
HVW55_02720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HVW55_02725	COG3117	lipopolysaccharide transmembrane transporter activity
HVW55_02730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HVW55_02735	COG0517	IMP dehydrogenase activity
HVW55_02735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVW55_02740	COG0530	calcium, potassium:sodium antiporter activity
HVW55_02745	COG1127	ABC transporter
HVW55_02750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HVW55_02755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVW55_02760	COG2854	intermembrane phospholipid transfer
HVW55_02765	COG3113	response to antibiotic
HVW55_02770	COG5007	Belongs to the BolA IbaG family
HVW55_02780	COG3423	Transcriptional regulator
HVW55_02785	COG0142	geranyltranstransferase activity
HVW55_02800	COG0697	spore germination
HVW55_02810	COG2027	D-alanyl-D-alanine carboxypeptidase
HVW55_02815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVW55_02820	COG1534	Rna-binding protein
HVW55_02830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HVW55_02835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HVW55_02845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVW55_02855	COG2194	sulfuric ester hydrolase activity
HVW55_02875	COG0195	Participates in both transcription termination and antitermination
HVW55_02915	COG0513	Belongs to the DEAD box helicase family
HVW55_02920	COG0814	amino acid
HVW55_02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HVW55_02930	COG0826	peptidase U32
HVW55_02935	COG0826	peptidase U32
HVW55_02940	COG3154	lipid carrier protein
HVW55_02945	COG3153	acetyltransferase
HVW55_02960	COG0693	protein deglycase activity
HVW55_02965	COG0702	epimerase
HVW55_02970	COG0701	Predicted permease
HVW55_02975	COG2823	Periplasmic or secreted lipoprotein
HVW55_02995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HVW55_03015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HVW55_03020	COG1263	PTS System
HVW55_03020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_03030	COG2222	sugar isomerase
HVW55_03035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVW55_03040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_03055	COG3423	Transcriptional regulator
HVW55_03060	COG2801	Transposase and inactivated derivatives
HVW55_03065	COG2842	Transposition protein
HVW55_03090	COG4396	Host-nuclease inhibitor protein Gam
HVW55_03140	COG5566	PFAM Mor transcription activator
HVW55_03165	COG0640	Transcriptional regulator
HVW55_03175	COG4373	Mu-like prophage FluMu protein gp28
HVW55_03180	COG4383	Mu-like prophage protein gp29
HVW55_03185	COG2369	cell adhesion
HVW55_03190	COG5005	Phage virion morphogenesis
HVW55_03195	COG4388	Caudovirus prohead serine protease
HVW55_03200	COG4397	Mu-like prophage major head subunit gpT
HVW55_03225	COG4386	tail sheath protein
HVW55_03235	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
HVW55_03245	COG4228	DNA circulation
HVW55_03255	COG4384	Bacteriophage Mu Gp45 protein
HVW55_03260	COG4381	Mu-like prophage protein gp46
HVW55_03265	COG3299	homolog of phage Mu protein gp47
HVW55_03275	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVW55_03290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVW55_03315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_03325	COG1349	DNA-binding transcription factor activity
HVW55_03335	COG2002	toxin-antitoxin pair type II binding
HVW55_03340	COG2721	sulfolactate sulfo-lyase activity
HVW55_03345	COG2271	Major facilitator Superfamily
HVW55_03355	COG2084	Dehydrogenase
HVW55_03360	COG1929	Belongs to the glycerate kinase type-1 family
HVW55_03385	COG0583	DNA-binding transcription factor activity
HVW55_03390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVW55_03400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HVW55_03405	COG1882	Formate acetyltransferase
HVW55_03410	COG0251	oxidation-reduction process
HVW55_03415	COG1760	l-serine dehydratase
HVW55_03420	COG0814	amino acid
HVW55_03435	COG1741	Belongs to the pirin family
HVW55_03440	COG0583	DNA-binding transcription factor activity
HVW55_03445	COG3152	Membrane
HVW55_03450	COG3152	Membrane
HVW55_03455	COG0435	Glutathione S-transferase
HVW55_03460	COG2259	Doxx family
HVW55_03470	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HVW55_03475	COG4575	ribosome binding
HVW55_03480	COG1422	Protein of unknown function (DUF1090)
HVW55_03490	COG0586	Pfam SNARE associated Golgi protein
HVW55_03495	COG2186	Transcriptional regulator
HVW55_03500	COG2271	Major facilitator Superfamily
HVW55_03510	COG2721	sulfolactate sulfo-lyase activity
HVW55_03520	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HVW55_03525	COG0861	Integral membrane protein TerC family
HVW55_03530	COG0673	inositol 2-dehydrogenase activity
HVW55_03535	COG2949	membrane
HVW55_03540	COG1451	nucleotide metabolic process
HVW55_03550	COG4680	protein conserved in bacteria
HVW55_03555	COG5499	transcription regulator containing HTH domain
HVW55_03560	COG1902	pentaerythritol trinitrate reductase activity
HVW55_03560	COG0446	pyridine nucleotide-disulphide oxidoreductase
HVW55_03565	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HVW55_03565	COG3408	Glycogen debranching enzyme
HVW55_03575	COG0531	amino acid
HVW55_03580	COG2731	YhcH YjgK YiaL family protein
HVW55_03585	COG3250	beta-galactosidase activity
HVW55_03590	COG1609	Transcriptional regulator
HVW55_03595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HVW55_03605	COG0840	transmembrane signaling receptor activity
HVW55_03610	COG1695	Transcriptional regulator
HVW55_03615	COG2375	cellular response to nickel ion
HVW55_03630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVW55_03635	COG0358	DNA primase activity
HVW55_03640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HVW55_03650	COG0471	metal ion transport
HVW55_03655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_03675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVW55_03690	COG4991	sh3 domain protein
HVW55_03695	COG3025	triphosphatase activity
HVW55_03725	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVW55_03755	COG3384	dioxygenase
HVW55_03760	COG0754	glutathionylspermidine amidase activity
HVW55_03770	COG1538	Outer membrane efflux protein
HVW55_03775	COG0494	nUDIX hydrolase
HVW55_03780	COG3151	Protein conserved in bacteria
HVW55_03785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HVW55_03790	COG3150	esterase
HVW55_03795	COG0187	DNA topoisomerase II activity
HVW55_03800	COG4774	siderophore transport
HVW55_03805	COG1120	ATPase activity
HVW55_03810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_03815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_03825	COG1737	Transcriptional regulator
HVW55_03830	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HVW55_03835	COG2249	NAD(P)H dehydrogenase (quinone) activity
HVW55_03840	COG0642	Histidine kinase
HVW55_03845	COG0745	RESPONSE REGULATOR receiver
HVW55_03850	COG3111	PFAM Bacterial OB fold (BOF) protein
HVW55_03855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HVW55_03860	COG4166	transmembrane transport
HVW55_03865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVW55_03870	COG0204	Acyl-transferase
HVW55_03875	COG2132	Multicopper oxidase
HVW55_03880	COG1032	radical SAM domain protein
HVW55_03885	COG4238	major outer membrane lipoprotein
HVW55_03895	COG0656	L-ascorbic acid biosynthetic process
HVW55_03900	COG1979	alcohol dehydrogenase
HVW55_03905	COG2207	Transcriptional regulator
HVW55_03910	COG0586	Pfam SNARE associated Golgi protein
HVW55_03915	COG0626	cystathionine gamma-synthase activity
HVW55_03920	COG0811	peptide transport
HVW55_03925	COG0848	biopolymer transport protein
HVW55_03930	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_03940	COG0667	Aldo Keto reductase
HVW55_03955	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVW55_03960	COG0437	4 iron, 4 sulfur cluster binding
HVW55_03965	COG5557	Pfam Polysulphide reductase, NrfD
HVW55_03970	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVW55_03975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVW55_03980	COG1773	rubredoxin
HVW55_03990	COG0298	carbon dioxide binding
HVW55_03995	COG0625	glutathione transferase activity
HVW55_04000	COG0754	glutathionylspermidine amidase activity
HVW55_04005	COG0306	phosphate transporter
HVW55_04010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HVW55_04015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HVW55_04020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HVW55_04025	COG2244	polysaccharide biosynthetic process
HVW55_04035	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HVW55_04040	COG0795	lipopolysaccharide-transporting ATPase activity
HVW55_04050	COG0156	8-amino-7-oxononanoate synthase activity
HVW55_04055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HVW55_04065	COG0318	PFAM AMP-dependent synthetase and ligase
HVW55_04070	COG0456	acetyltransferase
HVW55_04075	COG2186	Transcriptional regulator
HVW55_04080	COG0277	FAD linked oxidase domain protein
HVW55_04085	COG0277	FAD linked oxidase domain protein
HVW55_04090	COG0247	lactate metabolic process
HVW55_04095	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HVW55_04100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HVW55_04105	COG1620	l-lactate permease
HVW55_04135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVW55_04140	COG1459	type II secretion system
HVW55_04145	COG2165	general secretion pathway protein
HVW55_04160	COG4795	General secretion pathway protein
HVW55_04175	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HVW55_04210	COG2003	Belongs to the UPF0758 family
HVW55_04240	COG2020	methyltransferase activity
HVW55_04245	COG3468	outer membrane autotransporter barrel domain protein
HVW55_04330	COG5464	transposase or invertase
HVW55_04395	COG4372	Transposase
HVW55_04400	COG3436	PFAM IS66 Orf2 family protein
HVW55_04410	COG3344	reverse transcriptase
HVW55_04425	COG1438	arginine binding
HVW55_04430	COG1288	antiporter activity
HVW55_04445	COG2235	arginine
HVW55_04480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HVW55_04490	COG0732	type I restriction modification DNA specificity domain
HVW55_04495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HVW55_04505	COG0582	viral genome integration into host DNA
HVW55_04525	COG3706	GGDEF domain
HVW55_04535	COG2207	Transcriptional regulator
HVW55_04540	COG0582	viral genome integration into host DNA
HVW55_04575	COG0305	Participates in initiation and elongation during chromosome replication
HVW55_04620	COG3713	MltA-interacting MipA family protein
HVW55_04645	COG0629	single-stranded DNA binding
HVW55_04650	COG5464	transposase or invertase
HVW55_04780	COG3436	PFAM IS66 Orf2 family protein
HVW55_04785	COG4372	Transposase
HVW55_04925	COG0210	DNA helicase
HVW55_04935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HVW55_04945	COG1811	Na channel or pump
HVW55_04950	COG1982	Orn Lys Arg decarboxylase major
HVW55_04955	COG2211	Major facilitator Superfamily
HVW55_04970	COG1194	a g-specific adenine glycosylase
HVW55_04980	COG3171	Protein conserved in bacteria
HVW55_04995	COG0252	asparaginase activity
HVW55_05005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVW55_05020	COG0762	integral membrane protein
HVW55_05025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HVW55_05030	COG2805	Type II/IV secretion system protein
HVW55_05045	COG0189	ligase activity
HVW55_05050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HVW55_05055	COG2356	endonuclease I
HVW55_05065	COG2814	Major facilitator Superfamily
HVW55_05085	COG1166	arginine decarboxylase activity
HVW55_05100	COG0501	Belongs to the peptidase M48B family
HVW55_05105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVW55_05110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_05115	COG2213	PTS system mannitol-specific
HVW55_05120	COG1063	alcohol dehydrogenase
HVW55_05125	COG1494	fructose-1,6-bisphosphatase
HVW55_05130	COG3722	fumarate hydratase activity
HVW55_05135	COG1072	(Pantothenic acid kinase))
HVW55_05140	COG1122	ATPase activity
HVW55_05145	COG1122	ATPase activity
HVW55_05175	COG0191	fructose-bisphosphate aldolase activity
HVW55_05180	COG0668	transmembrane transport
HVW55_05195	COG1279	arginine transmembrane transporter activity
HVW55_05200	COG2968	Membrane
HVW55_05205	COG0583	DNA-binding transcription factor activity
HVW55_05210	COG0427	acetyl-CoA hydrolase
HVW55_05215	COG1024	Enoyl-CoA hydratase
HVW55_05220	COG1703	isobutyryl-CoA mutase activity
HVW55_05225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVW55_05225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVW55_05235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_05245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HVW55_05260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HVW55_05270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HVW55_05290	COG0006	proline dipeptidase activity
HVW55_05295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVW55_05300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVW55_05325	COG2723	6-phospho-beta-galactosidase activity
HVW55_05335	COG1272	protein, Hemolysin III
HVW55_05345	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HVW55_05355	COG0716	FMN binding
HVW55_05360	COG4974	Belongs to the 'phage' integrase family
HVW55_05365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVW55_05370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HVW55_05380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVW55_05400	COG2233	PERMEase
HVW55_05410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_05415	COG2252	PERMEase
HVW55_05420	COG0402	S-adenosylhomocysteine deaminase activity
HVW55_05425	COG2233	PERMEase
HVW55_05430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVW55_05430	COG2080	2 iron, 2 sulfur cluster binding
HVW55_05435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVW55_05440	COG0402	S-adenosylhomocysteine deaminase activity
HVW55_05445	COG0493	'glutamate synthase
HVW55_05445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_05450	COG2068	MobA-Related Protein
HVW55_05455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HVW55_05460	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HVW55_05460	COG3608	succinylglutamate desuccinylase aspartoacylase
HVW55_05465	COG0549	Belongs to the carbamate kinase family
HVW55_05475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HVW55_05480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVW55_05485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HVW55_05495	COG2080	2 iron, 2 sulfur cluster binding
HVW55_05500	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVW55_05505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVW55_05510	COG4942	peptidase
HVW55_05520	COG3387	PFAM Glycoside hydrolase 15-related
HVW55_05530	COG2207	Transcriptional regulator
HVW55_05590	COG0457	Tetratricopeptide repeat
HVW55_05590	COG3710	Transcriptional regulator
HVW55_05595	COG0457	Tetratricopeptide repeat
HVW55_05620	COG3710	Transcriptional regulator
HVW55_05625	COG2771	luxR family
HVW55_05630	COG0814	amino acid
HVW55_05635	COG0183	Belongs to the thiolase family
HVW55_05645	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_05650	COG2814	Major facilitator Superfamily
HVW55_05655	COG1794	racemase activity, acting on amino acids and derivatives
HVW55_05660	COG0583	DNA-binding transcription factor activity
HVW55_05670	COG1609	Transcriptional regulator
HVW55_05685	COG0667	Aldo Keto reductase
HVW55_05695	COG0861	Integral membrane protein TerC family
HVW55_05710	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HVW55_05725	COG2165	general secretion pathway protein
HVW55_05730	COG4795	General secretion pathway protein
HVW55_05740	COG4967	type IV pilus modification protein PilV
HVW55_05745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HVW55_05750	COG1025	Belongs to the peptidase M16 family
HVW55_05755	COG1074	ATP-dependent DNA helicase activity
HVW55_05760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HVW55_05765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HVW55_05765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HVW55_05770	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVW55_05790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HVW55_05795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HVW55_05800	COG2166	iron-sulfur cluster assembly
HVW55_05805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HVW55_05815	COG0583	DNA-binding transcription factor activity
HVW55_05820	COG2363	Small membrane protein
HVW55_05830	COG1349	DNA-binding transcription factor activity
HVW55_05840	COG1070	Carbohydrate kinase
HVW55_05850	COG0738	Major facilitator superfamily
HVW55_05855	COG0235	Class ii aldolase
HVW55_05860	COG1454	alcohol dehydrogenase
HVW55_05870	COG1760	l-serine dehydratase
HVW55_05875	COG0814	amino acid
HVW55_05880	COG1611	Belongs to the LOG family
HVW55_05895	COG3098	single-species biofilm formation
HVW55_05900	COG0564	pseudouridine synthase activity
HVW55_05905	COG0716	FMN binding
HVW55_05910	COG2271	Major facilitator Superfamily
HVW55_05915	COG4948	Mandelate Racemase Muconate Lactonizing
HVW55_05920	COG4948	Mandelate Racemase Muconate Lactonizing
HVW55_05925	COG3850	Histidine kinase
HVW55_05925	COG3437	response regulator, receiver
HVW55_05925	COG2205	protein histidine kinase activity
HVW55_05925	COG4999	Histidine kinase
HVW55_05935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVW55_05940	COG2336	PFAM SpoVT AbrB
HVW55_05945	COG2337	Toxic component of a toxin-antitoxin (TA) module
HVW55_05950	COG3956	TIGRFAM MazG family protein
HVW55_05965	COG3385	transposase activity
HVW55_05980	COG0602	queuosine metabolic process
HVW55_05985	COG1070	Carbohydrate kinase
HVW55_05990	COG2223	nitrite transmembrane transporter activity
HVW55_05995	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_06000	COG0277	FAD linked oxidase domain protein
HVW55_06005	COG0477	Major facilitator Superfamily
HVW55_06010	COG2086	electron transfer activity
HVW55_06015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HVW55_06020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HVW55_06025	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVW55_06030	COG0644	oxidoreductase
HVW55_06035	COG0720	synthase
HVW55_06055	COG1203	CRISPR-associated helicase, Cas3
HVW55_06070	COG1857	crispr-associated protein
HVW55_06085	COG1518	maintenance of DNA repeat elements
HVW55_06090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_06095	COG2234	aminopeptidase activity
HVW55_06150	COG4942	peptidase
HVW55_06150	COG1388	LysM domain
HVW55_06155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVW55_06165	COG0163	prenyltransferase activity
HVW55_06170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HVW55_06180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVW55_06200	COG3604	Transcriptional regulator
HVW55_06205	COG0309	Hydrogenase expression formation protein (HypE)
HVW55_06210	COG0409	Hydrogenase expression formation protein
HVW55_06215	COG0298	carbon dioxide binding
HVW55_06220	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HVW55_06225	COG0375	protein maturation
HVW55_06235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_06240	COG0651	ATP synthesis coupled electron transport
HVW55_06245	COG0650	Formate hydrogenlyase subunit 4
HVW55_06250	COG3261	NADH dehydrogenase
HVW55_06250	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVW55_06255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVW55_06260	COG3260	NADH ubiquinone oxidoreductase 20
HVW55_06270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVW55_06285	COG2723	6-phospho-beta-galactosidase activity
HVW55_06290	COG1263	PTS System
HVW55_06290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_06295	COG1609	Transcriptional regulator
HVW55_06300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_06305	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HVW55_06325	COG0517	IMP dehydrogenase activity
HVW55_06325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVW55_06330	COG1349	DNA-binding transcription factor activity
HVW55_06335	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_06340	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_06350	COG3732	PTS system glucitol sorbitol-specific
HVW55_06355	COG3730	PTS system glucitol sorbitol-specific
HVW55_06360	COG2951	lytic endotransglycosylase activity
HVW55_06365	COG1546	Belongs to the CinA family
HVW55_06385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HVW55_06415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVW55_06420	COG1238	metal cluster binding
HVW55_06445	COG2814	Major facilitator Superfamily
HVW55_06450	COG1566	PFAM secretion protein HlyD family protein
HVW55_06455	COG1846	Transcriptional regulator
HVW55_06465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HVW55_06470	COG2814	Major facilitator Superfamily
HVW55_06475	COG2113	Glycine betaine
HVW55_06480	COG4176	ABC-type proline glycine betaine transport system permease component
HVW55_06485	COG4175	Glycine betaine
HVW55_06490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVW55_06495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVW55_06505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVW55_06510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVW55_06520	COG4575	ribosome binding
HVW55_06535	COG2916	Histone family protein nucleoid-structuring protein H-NS
HVW55_06540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVW55_06545	COG0640	Transcriptional regulator
HVW55_06550	COG0401	homolog of Blt101
HVW55_06555	COG1652	LysM domain
HVW55_06560	COG1802	Transcriptional regulator
HVW55_06565	COG1113	amino acid transport
HVW55_06570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HVW55_06575	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_06580	COG0579	oxidoreductase
HVW55_06590	COG0366	Alpha amylase catalytic
HVW55_06675	COG0582	viral genome integration into host DNA
HVW55_06690	COG2867	negative regulation of translational initiation
HVW55_06700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVW55_06705	COG0497	DNA recombination
HVW55_06720	COG4536	flavin adenine dinucleotide binding
HVW55_06725	COG4137	Cytochrome C assembly protein
HVW55_06730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HVW55_06755	COG2885	chlorophyll binding
HVW55_06775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVW55_06780	COG0287	Prephenate dehydrogenase
HVW55_06780	COG1605	Chorismate mutase
HVW55_06785	COG0077	Prephenate dehydratase
HVW55_06785	COG1605	Chorismate mutase
HVW55_06795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVW55_06800	COG3385	transposase activity
HVW55_06805	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVW55_06810	COG0564	pseudouridine synthase activity
HVW55_06820	COG0542	response to heat
HVW55_06845	COG0477	Major facilitator Superfamily
HVW55_06850	COG5544	Lipoprotein
HVW55_06855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVW55_06860	COG1042	CoA-binding domain protein
HVW55_06860	COG0045	succinate-CoA ligase (ADP-forming) activity
HVW55_06860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVW55_06870	COG3118	belongs to the thioredoxin family
HVW55_06875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVW55_06890	COG1280	lysine exporter protein (LysE YggA)
HVW55_06895	COG0583	DNA-binding transcription factor activity
HVW55_06900	COG0513	Belongs to the DEAD box helicase family
HVW55_06910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HVW55_06920	COG1595	DNA-templated transcription, initiation
HVW55_06925	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HVW55_06930	COG3026	antisigma factor binding
HVW55_06935	COG3086	response to oxidative stress
HVW55_06945	COG0681	Belongs to the peptidase S26 family
HVW55_06965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HVW55_06980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_06985	COG1737	Transcriptional regulator
HVW55_06990	COG0560	Phosphoserine phosphatase
HVW55_06995	COG0590	tRNA wobble adenosine to inosine editing
HVW55_07005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HVW55_07005	COG0047	phosphoribosylformylglycinamidine synthase activity
HVW55_07010	COG2205	protein histidine kinase activity
HVW55_07015	COG3170	Tfp pilus assembly protein FimV
HVW55_07020	COG2204	response regulator
HVW55_07025	COG0347	Belongs to the P(II) protein family
HVW55_07030	COG1017	nitric oxide dioxygenase activity
HVW55_07030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_07040	COG1940	carbohydrate kinase activity
HVW55_07045	COG0457	Tetratricopeptide repeat
HVW55_07050	COG1879	ABC-type sugar transport system periplasmic component
HVW55_07055	COG1129	ABC transporter
HVW55_07060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_07065	COG1063	alcohol dehydrogenase
HVW55_07070	COG2017	converts alpha-aldose to the beta-anomer
HVW55_07075	COG2259	Doxx family
HVW55_07100	COG4638	Rieske (2fe-2S)
HVW55_07105	COG0583	DNA-binding transcription factor activity
HVW55_07110	COG2814	Major facilitator Superfamily
HVW55_07115	COG3711	transcriptional antiterminator
HVW55_07120	COG1073	alpha beta
HVW55_07125	COG0483	inositol monophosphate 1-phosphatase activity
HVW55_07145	COG0822	iron-sulfur transferase activity
HVW55_07165	COG0633	Ferredoxin
HVW55_07170	COG2975	iron-sulfur cluster assembly
HVW55_07190	COG2897	thiosulfate sulfurtransferase activity
HVW55_07195	COG2373	Large extracellular alpha-helical protein
HVW55_07200	COG4953	penicillin-binding protein 1C
HVW55_07230	COG2976	Protein conserved in bacteria
HVW55_07245	COG1645	bacterial-type flagellum-dependent swarming motility
HVW55_07270	COG0517	IMP dehydrogenase activity
HVW55_07270	COG0516	GMP reductase activity
HVW55_07295	COG3133	Outer membrane lipoprotein
HVW55_07310	COG2200	EAL domain
HVW55_07315	COG0248	Ppx GppA phosphatase
HVW55_07320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HVW55_07325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HVW55_07340	COG2233	PERMEase
HVW55_07350	COG1393	Belongs to the ArsC family
HVW55_07355	COG4783	chaperone-mediated protein folding
HVW55_07360	COG0628	permease
HVW55_07365	COG2116	formate transmembrane transporter activity
HVW55_07370	COG3604	Transcriptional regulator
HVW55_07380	COG3260	NADH ubiquinone oxidoreductase 20
HVW55_07385	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVW55_07390	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVW55_07390	COG3261	NADH dehydrogenase
HVW55_07395	COG0651	ATP synthesis coupled electron transport
HVW55_07400	COG4237	Hydrogenase 4 membrane
HVW55_07405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVW55_07410	COG0650	Formate hydrogenlyase subunit 4
HVW55_07415	COG0651	ATP synthesis coupled electron transport
HVW55_07420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_07425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HVW55_07430	COG2716	regulation of RNA biosynthetic process
HVW55_07440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HVW55_07460	COG2321	neutral zinc metallopeptidase
HVW55_07470	COG0400	carboxylic ester hydrolase activity
HVW55_07485	COG1393	Belongs to the ArsC family
HVW55_07495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_07500	COG3850	Histidine kinase
HVW55_07505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_07505	COG0493	'glutamate synthase
HVW55_07515	COG5342	invasion associated locus B
HVW55_07520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVW55_07525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVW55_07530	COG0281	malic enzyme
HVW55_07530	COG0280	phosphate acetyltransferase
HVW55_07535	COG4810	utilization protein
HVW55_07540	COG4917	ethanolamine utilization protein
HVW55_07545	COG4766	ethanolamine catabolic process
HVW55_07550	COG4812	Cobalamin adenosyltransferase
HVW55_07555	COG0280	phosphate acetyltransferase
HVW55_07560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVW55_07565	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HVW55_07570	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_07575	COG4820	ethanolamine utilization protein (EutJ)
HVW55_07580	COG1454	alcohol dehydrogenase
HVW55_07585	COG3192	ethanolamine utilization protein
HVW55_07590	COG4819	ethanolamine utilization protein
HVW55_07595	COG4303	Ethanolamine ammonia lyase large subunit
HVW55_07605	COG4816	utilization protein
HVW55_07610	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVW55_07615	COG2207	Transcriptional regulator
HVW55_07625	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVW55_07645	COG2837	iron assimilation
HVW55_07650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVW55_07655	COG1263	PTS System
HVW55_07655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_07670	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_07675	COG4150	thiosulfate binding
HVW55_07680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HVW55_07685	COG4208	sulfate ABC transporter
HVW55_07690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HVW55_07695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVW55_07710	COG2190	(PTS) system
HVW55_07715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVW55_07720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_07725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVW55_07745	COG3530	Putative quorum-sensing-regulated virulence factor
HVW55_07750	COG0385	Bile acid
HVW55_07755	COG0583	DNA-binding transcription factor activity
HVW55_07790	COG3415	Transposase
HVW55_07795	COG3415	Transposase
HVW55_07810	COG2200	EAL domain
HVW55_07810	COG2199	diguanylate cyclase activity
HVW55_07815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVW55_07840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_07845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_07850	COG0006	proline dipeptidase activity
HVW55_07855	COG1363	Peptidase, m42
HVW55_07860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_07860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVW55_07860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_07865	COG2207	Transcriptional regulator
HVW55_07870	COG3279	Response regulator of the LytR AlgR family
HVW55_07875	COG3275	phosphorelay sensor kinase activity
HVW55_07880	COG0436	Aminotransferase
HVW55_07890	COG1560	Kdo2-lipid A biosynthetic process
HVW55_07915	COG0028	Belongs to the TPP enzyme family
HVW55_07920	COG0679	Auxin Efflux Carrier
HVW55_07925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HVW55_07930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_07930	COG2198	Histidine kinase
HVW55_07930	COG2205	protein histidine kinase activity
HVW55_07930	COG0784	Response regulator, receiver
HVW55_07935	COG2197	response regulator
HVW55_07940	COG1566	PFAM secretion protein HlyD family protein
HVW55_07945	COG0477	Major facilitator Superfamily
HVW55_07990	COG2116	formate transmembrane transporter activity
HVW55_07995	COG2853	Lipoprotein
HVW55_08005	COG2067	long-chain fatty acid transport protein
HVW55_08010	COG3691	Protein conserved in bacteria
HVW55_08025	COG2062	phosphohistidine phosphatase, SixA
HVW55_08030	COG3539	Fimbrial protein
HVW55_08040	COG3121	Chaperone
HVW55_08045	COG3539	Fimbrial protein
HVW55_08050	COG3539	Fimbrial protein
HVW55_08055	COG3539	Fimbrial protein
HVW55_08070	COG2890	protein-(glutamine-N5) methyltransferase activity
HVW55_08085	COG0730	response to heat
HVW55_08090	COG3101	peptidyl-lysine hydroxylation
HVW55_08105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVW55_08110	COG2814	Major facilitator Superfamily
HVW55_08190	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVW55_08270	COG4695	Portal protein
HVW55_08360	COG4974	Belongs to the 'phage' integrase family
HVW55_08370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVW55_08380	COG0586	Pfam SNARE associated Golgi protein
HVW55_08390	COG0285	dihydrofolate synthase activity
HVW55_08395	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HVW55_08400	COG1286	toxin biosynthetic process
HVW55_08405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HVW55_08410	COG0163	prenyltransferase activity
HVW55_08415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_08425	COG4215	(ABC) transporter
HVW55_08430	COG4160	amino acid transport
HVW55_08435	COG4598	ABC transporter
HVW55_08440	COG5464	transposase or invertase
HVW55_08445	COG1090	epimerase
HVW55_08450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVW55_08455	COG0625	glutathione transferase activity
HVW55_08460	COG0625	glutathione transferase activity
HVW55_08465	COG0622	Phosphoesterase
HVW55_08470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HVW55_08475	COG1288	antiporter activity
HVW55_08480	COG0857	belongs to the CobB CobQ family
HVW55_08480	COG0280	phosphate acetyltransferase
HVW55_08485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HVW55_08500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVW55_08505	COG0490	domain, Protein
HVW55_08505	COG0471	metal ion transport
HVW55_08515	COG0436	Aminotransferase
HVW55_08520	COG0583	DNA-binding transcription factor activity
HVW55_08540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HVW55_08545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HVW55_08550	COG1034	ATP synthesis coupled electron transport
HVW55_08565	COG0839	Belongs to the complex I subunit 6 family
HVW55_08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVW55_08580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVW55_08610	COG2153	protein acetylation
HVW55_08615	COG4575	ribosome binding
HVW55_08620	COG1169	isochorismate synthase
HVW55_08635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HVW55_08645	COG0318	PFAM AMP-dependent synthetase and ligase
HVW55_08710	COG1414	Transcriptional regulator
HVW55_08720	COG2271	Major facilitator Superfamily
HVW55_08725	COG3836	Belongs to the HpcH HpaI aldolase family
HVW55_08735	COG5464	transposase or invertase
HVW55_08740	COG0247	lactate metabolic process
HVW55_08750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVW55_08755	COG2271	Major facilitator Superfamily
HVW55_08760	COG0584	glycerophosphoryl diester phosphodiesterase
HVW55_08775	COG3642	lipopolysaccharide core region biosynthetic process
HVW55_08780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_08785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVW55_08790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVW55_08795	COG3468	outer membrane autotransporter barrel domain protein
HVW55_08805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVW55_08810	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HVW55_08815	COG3234	Protein of unknown function (DUF1175)
HVW55_08820	COG2373	Large extracellular alpha-helical protein
HVW55_08830	COG4676	Protein conserved in bacteria
HVW55_08835	COG2205	protein histidine kinase activity
HVW55_08835	COG0784	Response regulator, receiver
HVW55_08840	COG2197	response regulator
HVW55_08845	COG0642	Histidine kinase
HVW55_08845	COG2198	Histidine kinase
HVW55_08850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVW55_08855	COG1477	protein flavinylation
HVW55_08860	COG2169	Transcriptional regulator
HVW55_08860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVW55_08865	COG3145	DNA-N1-methyladenine dioxygenase activity
HVW55_08870	COG4615	Cyclic peptide transporter
HVW55_08890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_08890	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVW55_08895	COG3062	negative regulation of establishment of protein localization
HVW55_08905	COG0437	4 iron, 4 sulfur cluster binding
HVW55_08910	COG0348	domain, Protein
HVW55_08915	COG3043	anaerobic respiration
HVW55_08920	COG3005	denitrification pathway
HVW55_08925	COG4133	protoheme IX ABC transporter activity
HVW55_08930	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVW55_08935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVW55_08940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVW55_08950	COG1138	Cytochrome C-type biogenesis protein
HVW55_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HVW55_08960	COG4235	cytochrome complex assembly
HVW55_08960	COG3088	subunit of a heme lyase
HVW55_08965	COG2197	response regulator
HVW55_08970	COG3468	outer membrane autotransporter barrel domain protein
HVW55_08980	COG3083	sulfuric ester hydrolase activity
HVW55_09000	COG1061	Type III restriction enzyme res subunit
HVW55_09005	COG1187	pseudouridine synthase activity
HVW55_09010	COG2814	Major facilitator Superfamily
HVW55_09020	COG4172	Belongs to the ABC transporter superfamily
HVW55_09025	COG4239	(ABC) transporter, permease
HVW55_09030	COG4174	ABC transporter (Permease)
HVW55_09035	COG4166	transmembrane transport
HVW55_09040	COG2200	EAL domain
HVW55_09045	COG0791	NLP P60 protein
HVW55_09050	COG0671	phosphoesterase, PA-phosphatase related
HVW55_09055	COG0523	cobalamin synthesis protein
HVW55_09060	COG0246	Mannitol dehydrogenase
HVW55_09075	COG2814	Major facilitator Superfamily
HVW55_09080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_09080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_09085	COG1105	Belongs to the carbohydrate kinase PfkB family
HVW55_09090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HVW55_09090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_09090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_09095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_09100	COG2313	pseudouridylate synthase activity
HVW55_09105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVW55_09110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVW55_09120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVW55_09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_09125	COG1522	sequence-specific DNA binding
HVW55_09135	COG2855	membrane
HVW55_09140	COG0583	DNA-binding transcription factor activity
HVW55_09145	COG0833	amino acid
HVW55_09150	COG4771	TonB-dependent receptor
HVW55_09155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HVW55_09165	COG2311	Membrane
HVW55_09170	COG1609	Transcriptional regulator
HVW55_09175	COG1879	ABC-type sugar transport system periplasmic component
HVW55_09180	COG1129	ABC transporter
HVW55_09185	COG4211	Belongs to the binding-protein-dependent transport system permease family
HVW55_09190	COG0167	dihydroorotate dehydrogenase activity
HVW55_09190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HVW55_09195	COG0493	'glutamate synthase
HVW55_09205	COG2949	membrane
HVW55_09215	COG1346	cytolysis
HVW55_09225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVW55_09240	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_09245	COG0586	Pfam SNARE associated Golgi protein
HVW55_09255	COG1686	Belongs to the peptidase S11 family
HVW55_09260	COG0277	FAD linked oxidase domain protein
HVW55_09265	COG1472	Belongs to the glycosyl hydrolase 3 family
HVW55_09270	COG1732	Glycine betaine
HVW55_09275	COG1174	glycine betaine transport
HVW55_09280	COG1125	glycine betaine transport
HVW55_09285	COG1174	glycine betaine transport
HVW55_09295	COG0789	Transcriptional regulator
HVW55_09300	COG3275	phosphorelay sensor kinase activity
HVW55_09305	COG3279	Response regulator of the LytR AlgR family
HVW55_09310	COG4807	Protein conserved in bacteria
HVW55_09315	COG4808	Protein conserved in bacteria
HVW55_09320	COG4715	Zinc finger, swim domain protein
HVW55_09325	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HVW55_09330	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HVW55_09335	COG0714	Associated with various cellular activities
HVW55_09345	COG3831	ATPase activity
HVW55_09350	COG3831	ATPase activity
HVW55_09360	COG0489	protein tyrosine kinase activity
HVW55_09370	COG3539	Fimbrial protein
HVW55_09375	COG3121	Chaperone
HVW55_09380	COG3188	usher protein
HVW55_09385	COG3539	Fimbrial protein
HVW55_09390	COG5455	response to cobalt ion
HVW55_09410	COG0351	phosphomethylpyrimidine kinase
HVW55_09415	COG3757	hydrolase, family 25
HVW55_09420	COG2188	Transcriptional regulator
HVW55_09425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_09430	COG1397	ADP-ribosylglycohydrolase
HVW55_09435	COG2211	Major facilitator Superfamily
HVW55_09440	COG1830	Aldolase
HVW55_09455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_09460	COG3414	Phosphotransferase system galactitol-specific IIB component
HVW55_09465	COG3775	system Galactitol-specific IIC component
HVW55_09470	COG1063	alcohol dehydrogenase
HVW55_09500	COG3609	addiction module antidote protein, CC2985 family
HVW55_09510	COG0745	RESPONSE REGULATOR receiver
HVW55_09515	COG2205	protein histidine kinase activity
HVW55_09530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_09555	COG4245	von Willebrand factor, type A
HVW55_09560	COG0631	protein serine/threonine phosphatase activity
HVW55_09565	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HVW55_09570	COG0443	Heat shock 70 kDa protein
HVW55_09575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HVW55_09580	COG5001	Diguanylate cyclase
HVW55_09580	COG5002	protein histidine kinase activity
HVW55_09580	COG3447	MASE1 domain protein
HVW55_09585	COG0572	uridine kinase
HVW55_09595	COG2982	Protein involved in outer membrane biogenesis
HVW55_09610	COG1253	flavin adenine dinucleotide binding
HVW55_09620	COG1596	polysaccharide export
HVW55_09625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HVW55_09630	COG0489	protein tyrosine kinase activity
HVW55_09630	COG3206	protein involved in exopolysaccharide biosynthesis
HVW55_09635	COG0463	Glycosyl transferase, family 2
HVW55_09640	COG1045	serine acetyltransferase
HVW55_09645	COG0438	transferase activity, transferring glycosyl groups
HVW55_09655	COG1216	Glycosyl transferase, family 2
HVW55_09660	COG0110	maltose O-acetyltransferase activity
HVW55_09665	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HVW55_09670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVW55_09675	COG1051	belongs to the nudix hydrolase family
HVW55_09680	COG0297	glycogen (starch) synthase activity
HVW55_09685	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HVW55_09685	COG0662	Cupin 2, conserved barrel domain protein
HVW55_09690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HVW55_09695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HVW55_09700	COG2244	polysaccharide biosynthetic process
HVW55_09705	COG2327	Polysaccharide pyruvyl transferase
HVW55_09710	COG0438	transferase activity, transferring glycosyl groups
HVW55_09720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVW55_09730	COG1215	transferase activity, transferring glycosyl groups
HVW55_09740	COG0438	transferase activity, transferring glycosyl groups
HVW55_09750	COG0438	transferase activity, transferring glycosyl groups
HVW55_09755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HVW55_09775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVW55_09795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HVW55_09800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVW55_09800	COG0131	Imidazoleglycerol-phosphate dehydratase
HVW55_09810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HVW55_09825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVW55_09830	COG0583	DNA-binding transcription factor activity
HVW55_09840	COG0531	amino acid
HVW55_09845	COG2391	methyltransferase activity
HVW55_09850	COG0425	Belongs to the sulfur carrier protein TusA family
HVW55_09855	COG2925	Exonuclease
HVW55_09860	COG1686	Belongs to the peptidase S11 family
HVW55_09870	COG1289	transmembrane transporter activity
HVW55_09880	COG4917	ethanolamine utilization protein
HVW55_09885	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HVW55_09900	COG1376	ErfK ybiS ycfS ynhG family protein
HVW55_09910	COG0583	DNA-binding transcription factor activity
HVW55_09915	COG0583	DNA-binding transcription factor activity
HVW55_09925	COG0534	Mate efflux family protein
HVW55_09935	COG0217	transcriptional regulatory protein
HVW55_09940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HVW55_09945	COG0477	Major facilitator Superfamily
HVW55_09955	COG1388	LysM domain
HVW55_09955	COG2373	Large extracellular alpha-helical protein
HVW55_09955	COG4932	domain protein
HVW55_09975	COG3038	cytochrome b561
HVW55_09980	COG3443	Belongs to the bacterial solute-binding protein 9 family
HVW55_09995	COG2351	hydroxyisourate hydrolase activity
HVW55_10000	COG0745	RESPONSE REGULATOR receiver
HVW55_10005	COG2205	protein histidine kinase activity
HVW55_10020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVW55_10030	COG1418	mRNA catabolic process
HVW55_10035	COG0270	DNA (cytosine-5-)-methyltransferase activity
HVW55_10040	COG3727	T/G mismatch-specific endonuclease activity
HVW55_10045	COG0697	spore germination
HVW55_10050	COG2354	Protein conserved in bacteria
HVW55_10055	COG5475	Uncharacterized small protein (DUF2158)
HVW55_10060	COG3706	GGDEF domain
HVW55_10080	COG2197	response regulator
HVW55_10085	COG1684	flagellar biosynthetic protein fliR
HVW55_10090	COG1987	bacterial-type flagellum assembly
HVW55_10095	COG1338	Plays a role in the flagellum-specific transport system
HVW55_10100	COG3190	flagellar
HVW55_10105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVW55_10110	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVW55_10115	COG1580	Controls the rotational direction of flagella during chemotaxis
HVW55_10120	COG3144	bacterial-type flagellum assembly
HVW55_10125	COG2882	bacterial-type flagellum organization
HVW55_10130	COG1157	protein secretion by the type III secretion system
HVW55_10135	COG1317	bacterial-type flagellum organization
HVW55_10140	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVW55_10145	COG1766	The M ring may be actively involved in energy transduction
HVW55_10160	COG0454	-acetyltransferase
HVW55_10165	COG2135	peptidase activity
HVW55_10170	COG0425	Belongs to the sulfur carrier protein TusA family
HVW55_10175	COG2391	methyltransferase activity
HVW55_10185	COG0366	Alpha amylase catalytic
HVW55_10195	COG1516	flagellar protein fliS
HVW55_10200	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HVW55_10210	COG1191	sigma factor activity
HVW55_10240	COG2197	response regulator
HVW55_10255	COG2197	response regulator
HVW55_10285	COG3012	SEC-C Motif Domain Protein
HVW55_10285	COG3318	Belongs to the UPF0149 family
HVW55_10290	COG0814	amino acid
HVW55_10300	COG1528	Iron-storage protein
HVW55_10320	COG1528	Iron-storage protein
HVW55_10325	COG1879	ABC-type sugar transport system periplasmic component
HVW55_10330	COG1129	ABC transporter
HVW55_10335	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_10340	COG1877	trehalose-phosphatase activity
HVW55_10350	COG0589	response to stress
HVW55_10365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HVW55_10370	COG1360	Flagellar Motor Protein
HVW55_10375	COG0643	Histidine kinase
HVW55_10375	COG2198	Histidine kinase
HVW55_10380	COG0835	chemotaxis
HVW55_10385	COG0840	transmembrane signaling receptor activity
HVW55_10390	COG0840	transmembrane signaling receptor activity
HVW55_10395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HVW55_10405	COG0745	RESPONSE REGULATOR receiver
HVW55_10410	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HVW55_10420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HVW55_10425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HVW55_10430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HVW55_10440	COG3755	Protein conserved in bacteria
HVW55_10450	COG3102	Protein conserved in bacteria
HVW55_10460	COG3005	denitrification pathway
HVW55_10465	COG0243	molybdopterin cofactor binding
HVW55_10480	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HVW55_10485	COG1801	Protein of unknown function DUF72
HVW55_10490	COG1335	isochorismatase
HVW55_10500	COG0494	nUDIX hydrolase
HVW55_10505	COG0217	transcriptional regulatory protein
HVW55_10535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HVW55_10545	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HVW55_10550	COG0739	heme binding
HVW55_10555	COG1560	Kdo2-lipid A biosynthetic process
HVW55_10560	COG0469	pyruvate kinase activity
HVW55_10565	COG1737	Transcriptional regulator
HVW55_10570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HVW55_10575	COG0129	dihydroxy-acid dehydratase activity
HVW55_10580	COG0800	Aldolase
HVW55_10590	COG3141	response to X-ray
HVW55_10600	COG2979	Protein of unknown function (DUF533)
HVW55_10605	COG1770	oligopeptidase
HVW55_10610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_10615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVW55_10625	COG2372	response to copper ion
HVW55_10630	COG1276	copper resistance
HVW55_10640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVW55_10660	COG3008	intermembrane lipid transfer
HVW55_10665	COG2995	paraquat-inducible protein a
HVW55_10670	COG1956	GAF domain-containing protein
HVW55_10680	COG0793	Belongs to the peptidase S41A family
HVW55_10690	COG2814	Major facilitator Superfamily
HVW55_10695	COG1414	Transcriptional regulator
HVW55_10725	COG2226	methyltransferase
HVW55_10740	COG3716	PTS system mannose fructose sorbose family IID component
HVW55_10745	COG3715	PTS system
HVW55_10750	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_10750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_10755	COG1253	flavin adenine dinucleotide binding
HVW55_10760	COG2200	EAL domain
HVW55_10765	COG1760	l-serine dehydratase
HVW55_10775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVW55_10790	COG0251	oxidation-reduction process
HVW55_10795	COG1199	ATP-dependent helicase activity
HVW55_10800	COG1214	PFAM Peptidase M22, glycoprotease
HVW55_10805	COG3065	identical protein binding
HVW55_10810	COG0318	PFAM AMP-dependent synthetase and ligase
HVW55_10815	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HVW55_10820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_10825	COG4638	Rieske (2fe-2S)
HVW55_10830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HVW55_10835	COG0473	3-isopropylmalate dehydrogenase activity
HVW55_10840	COG0583	DNA-binding transcription factor activity
HVW55_10850	COG3615	Tellurite resistance protein tehB
HVW55_10860	COG2261	transglycosylase associated protein
HVW55_10875	COG2199	diguanylate cyclase activity
HVW55_10875	COG2203	Gaf domain
HVW55_10880	COG3042	response to heat
HVW55_10885	COG3189	MarR family transcriptional regulator
HVW55_10890	COG2807	transmembrane transport
HVW55_10895	COG2207	Transcriptional regulator
HVW55_10910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVW55_10915	COG2199	diguanylate cyclase activity
HVW55_10920	COG2199	diguanylate cyclase activity
HVW55_10930	COG2766	serine protein kinase
HVW55_10935	COG3713	MltA-interacting MipA family protein
HVW55_10940	COG0656	L-ascorbic acid biosynthetic process
HVW55_10945	COG0676	glucose-6-phosphate 1-epimerase activity
HVW55_10950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HVW55_10960	COG3139	Protein of unknown function (DUF1315)
HVW55_10965	COG1063	alcohol dehydrogenase
HVW55_10970	COG2271	Major facilitator Superfamily
HVW55_10975	COG1063	alcohol dehydrogenase
HVW55_10980	COG0191	fructose-bisphosphate aldolase activity
HVW55_10985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_10990	COG0667	Aldo Keto reductase
HVW55_10995	COG1349	DNA-binding transcription factor activity
HVW55_11005	COG1335	isochorismatase
HVW55_11010	COG0252	asparaginase activity
HVW55_11020	COG0616	signal peptide processing
HVW55_11025	COG0778	Nitroreductase
HVW55_11030	COG0709	Synthesizes selenophosphate from selenide and ATP
HVW55_11035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVW55_11045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HVW55_11055	COG0494	nUDIX hydrolase
HVW55_11060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HVW55_11065	COG2897	thiosulfate sulfurtransferase activity
HVW55_11070	COG4136	ATPase activity
HVW55_11075	COG4135	transport system, permease component
HVW55_11080	COG4134	Bacterial extracellular solute-binding protein
HVW55_11085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVW55_11090	COG0398	Pfam SNARE associated Golgi protein
HVW55_11100	COG0398	Pfam SNARE associated Golgi protein
HVW55_11105	COG0708	Exodeoxyribonuclease III
HVW55_11135	COG3678	ATP-independent chaperone mediated protein folding
HVW55_11145	COG0322	excinuclease ABC activity
HVW55_11155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVW55_11160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVW55_11165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVW55_11170	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVW55_11175	COG1917	Cupin 2, conserved barrel domain protein
HVW55_11175	COG2169	Transcriptional regulator
HVW55_11180	COG1486	melibiose metabolic process
HVW55_11190	COG0753	catalase activity
HVW55_11210	COG1988	membrane-bound metal-dependent
HVW55_11215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVW55_11225	COG3001	Fructosamine kinase
HVW55_11235	COG1105	Belongs to the carbohydrate kinase PfkB family
HVW55_11240	COG3137	Salt-induced outer membrane protein
HVW55_11285	COG0072	phenylalanine-tRNA ligase activity
HVW55_11285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HVW55_11300	COG0386	Belongs to the glutathione peroxidase family
HVW55_11310	COG0791	NLP P60 protein
HVW55_11315	COG2200	EAL domain
HVW55_11325	COG4256	Hemin uptake protein
HVW55_11330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVW55_11340	COG0574	Belongs to the PEP-utilizing enzyme family
HVW55_11340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVW55_11345	COG0471	metal ion transport
HVW55_11350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HVW55_11360	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_11365	COG0318	PFAM AMP-dependent synthetase and ligase
HVW55_11370	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVW55_11375	COG0644	oxidoreductase
HVW55_11380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HVW55_11385	COG2086	electron transfer activity
HVW55_11390	COG1917	Cupin 2, conserved barrel domain protein
HVW55_11390	COG2207	Transcriptional regulator
HVW55_11395	COG1960	acyl-CoA dehydrogenase activity
HVW55_11400	COG4670	ketone body catabolic process
HVW55_11415	COG2271	Major facilitator Superfamily
HVW55_11420	COG0738	Major facilitator superfamily
HVW55_11435	COG0628	permease
HVW55_11440	COG0277	FAD linked oxidase domain protein
HVW55_11440	COG0247	lactate metabolic process
HVW55_11445	COG2050	protein possibly involved in aromatic compounds catabolism
HVW55_11455	COG0316	Belongs to the HesB IscA family
HVW55_11460	COG0719	Fe-S assembly protein
HVW55_11465	COG0396	ATPase activity
HVW55_11470	COG0719	Fe-S assembly protein
HVW55_11485	COG1376	ErfK ybiS ycfS ynhG family protein
HVW55_11490	COG4238	major outer membrane lipoprotein
HVW55_11495	COG0469	pyruvate kinase activity
HVW55_11505	COG0437	4 iron, 4 sulfur cluster binding
HVW55_11510	COG2414	aldehyde ferredoxin oxidoreductase
HVW55_11520	COG0437	4 iron, 4 sulfur cluster binding
HVW55_11525	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HVW55_11535	COG4529	Protein conserved in bacteria
HVW55_11555	COG3468	outer membrane autotransporter barrel domain protein
HVW55_11565	COG0307	riboflavin synthase, alpha
HVW55_11570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HVW55_11575	COG2814	Major facilitator Superfamily
HVW55_11580	COG0583	DNA-binding transcription factor activity
HVW55_11595	COG2814	Major facilitator Superfamily
HVW55_11600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVW55_11605	COG0791	NLP P60 protein
HVW55_11610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HVW55_11615	COG1201	RNA secondary structure unwinding
HVW55_11625	COG0346	lactoylglutathione lyase activity
HVW55_11630	COG1902	pentaerythritol trinitrate reductase activity
HVW55_11635	COG1309	transcriptional regulator
HVW55_11640	COG3313	Fe-S protein
HVW55_11645	COG4989	oxidoreductase activity
HVW55_11650	COG2032	superoxide dismutase activity
HVW55_11655	COG1289	transmembrane transporter activity
HVW55_11660	COG1566	PFAM secretion protein HlyD family protein
HVW55_11675	COG3133	Outer membrane lipoprotein
HVW55_11685	COG3895	Periplasmic Protein
HVW55_11700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HVW55_11705	COG0625	glutathione transferase activity
HVW55_11710	COG3104	oligopeptide transport
HVW55_11715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HVW55_11725	COG4659	FMN binding
HVW55_11775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HVW55_11780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_11780	COG1263	PTS System
HVW55_11785	COG1609	Transcriptional regulator
HVW55_11790	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_11795	COG1309	transcriptional regulator
HVW55_11800	COG3250	beta-galactosidase activity
HVW55_11815	COG5339	Protein conserved in bacteria
HVW55_11820	COG1482	cell wall glycoprotein biosynthetic process
HVW55_11825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_11825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_11830	COG0114	fumarate hydratase activity
HVW55_11840	COG2205	protein histidine kinase activity
HVW55_11845	COG0745	RESPONSE REGULATOR receiver
HVW55_11850	COG3136	membrane protein required for alginate biosynthesis
HVW55_11860	COG0531	amino acid
HVW55_11870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HVW55_11875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HVW55_11880	COG0628	permease
HVW55_11895	COG3591	Belongs to the peptidase S1B family
HVW55_11910	COG2814	Major facilitator Superfamily
HVW55_11915	COG0583	DNA-binding transcription factor activity
HVW55_11920	COG1940	carbohydrate kinase activity
HVW55_11925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVW55_11935	COG3381	protein complex oligomerization
HVW55_11940	COG3302	dmso reductase anchor subunit
HVW55_11945	COG0437	4 iron, 4 sulfur cluster binding
HVW55_11950	COG0243	molybdopterin cofactor binding
HVW55_11955	COG0243	molybdopterin cofactor binding
HVW55_11970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVW55_11985	COG4948	Mandelate Racemase Muconate Lactonizing
HVW55_11990	COG1063	alcohol dehydrogenase
HVW55_12000	COG0582	viral genome integration into host DNA
HVW55_12015	COG3436	PFAM IS66 Orf2 family protein
HVW55_12020	COG4372	Transposase
HVW55_12030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_12055	COG1396	sequence-specific DNA binding
HVW55_12070	COG1846	Transcriptional regulator
HVW55_12090	COG2801	Transposase and inactivated derivatives
HVW55_12105	COG3077	Addiction module antitoxin, RelB DinJ family
HVW55_12110	COG2026	Addiction module toxin, RelE StbE family
HVW55_12130	COG1403	HNH endonuclease
HVW55_12135	COG0484	heat shock protein binding
HVW55_12145	COG1278	Cold shock
HVW55_12150	COG1278	Cold shock
HVW55_12165	COG3772	lysozyme
HVW55_12175	COG1278	Cold shock
HVW55_12200	COG5562	phage envelope protein
HVW55_12210	COG4220	transposase activity
HVW55_12230	COG1030	water channel activity
HVW55_12280	COG1196	nuclear chromosome segregation
HVW55_12315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVW55_12320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVW55_12340	COG0246	Mannitol dehydrogenase
HVW55_12350	COG1802	Transcriptional regulator
HVW55_12355	COG4221	oxidoreductase activity
HVW55_12360	COG0339	signal peptide processing
HVW55_12365	COG1546	Belongs to the CinA family
HVW55_12370	COG3111	PFAM Bacterial OB fold (BOF) protein
HVW55_12385	COG2814	Major facilitator Superfamily
HVW55_12390	COG0697	spore germination
HVW55_12395	COG2188	Transcriptional regulator
HVW55_12405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVW55_12410	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVW55_12420	COG2723	6-phospho-beta-galactosidase activity
HVW55_12430	COG4977	sequence-specific DNA binding
HVW55_12435	COG1846	Transcriptional regulator
HVW55_12455	COG0583	DNA-binding transcription factor activity
HVW55_12460	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_12465	COG2066	Belongs to the glutaminase family
HVW55_12475	COG2199	diguanylate cyclase activity
HVW55_12485	COG3781	membrane
HVW55_12530	COG1070	Carbohydrate kinase
HVW55_12540	COG3210	domain, Protein
HVW55_12540	COG2911	Protein conserved in bacteria
HVW55_12545	COG1396	sequence-specific DNA binding
HVW55_12550	COG3550	peptidyl-serine autophosphorylation
HVW55_12560	COG3539	Fimbrial protein
HVW55_12570	COG3188	usher protein
HVW55_12575	COG3539	Fimbrial protein
HVW55_12580	COG3539	Fimbrial protein
HVW55_12585	COG3539	Fimbrial protein
HVW55_12590	COG0243	molybdopterin cofactor binding
HVW55_12605	COG3119	arylsulfatase activity
HVW55_12610	COG0641	radical SAM
HVW55_12620	COG4178	(ABC) transporter
HVW55_12625	COG4771	TonB-dependent receptor
HVW55_12630	COG0612	Peptidase, M16
HVW55_12635	COG0076	glutamate decarboxylase activity
HVW55_12640	COG0531	amino acid
HVW55_12655	COG3706	GGDEF domain
HVW55_12660	COG2200	EAL domain
HVW55_12660	COG2199	diguanylate cyclase activity
HVW55_12660	COG2202	Pas domain
HVW55_12665	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HVW55_12670	COG0747	negative chemotaxis
HVW55_12675	COG0601	transmembrane transport
HVW55_12680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVW55_12685	COG0444	Belongs to the ABC transporter superfamily
HVW55_12690	COG4608	Belongs to the ABC transporter superfamily
HVW55_12700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HVW55_12705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HVW55_12715	COG1250	3-hydroxyacyl-CoA dehydrogenase
HVW55_12720	COG2610	gluconate transmembrane transporter activity
HVW55_12725	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_12730	COG1764	response to oxidative stress
HVW55_12750	COG1064	alcohol dehydrogenase
HVW55_12760	COG3093	addiction module antidote protein HigA
HVW55_12765	COG2864	formate dehydrogenase
HVW55_12770	COG0437	4 iron, 4 sulfur cluster binding
HVW55_12780	COG0697	spore germination
HVW55_12790	COG4886	Leucine-rich repeat (LRR) protein
HVW55_12795	COG4886	Leucine-rich repeat (LRR) protein
HVW55_12800	COG2223	nitrite transmembrane transporter activity
HVW55_12805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVW55_12810	COG1140	nitrate reductase beta subunit
HVW55_12815	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVW55_12820	COG2181	nitrate reductase activity
HVW55_12825	COG0384	phenazine biosynthesis protein PhzF
HVW55_12830	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HVW55_12835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVW55_12845	COG5433	transposase activity
HVW55_12870	COG3501	Rhs element vgr protein
HVW55_12880	COG0625	glutathione transferase activity
HVW55_12885	COG1113	amino acid transport
HVW55_12890	COG3391	amine dehydrogenase activity
HVW55_12895	COG4772	TonB-dependent receptor
HVW55_12900	COG1802	Transcriptional regulator
HVW55_12905	COG2130	NADP-dependent
HVW55_12910	COG1247	-acetyltransferase
HVW55_12915	COG3238	Protein conserved in bacteria
HVW55_12940	COG1177	transmembrane transport
HVW55_12945	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVW55_12950	COG3842	ATPase activity
HVW55_12955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVW55_12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HVW55_12965	COG1598	PFAM Uncharacterised protein family UPF0150
HVW55_12970	COG1724	mRNA binding
HVW55_12980	COG0826	peptidase U32
HVW55_12985	COG1396	sequence-specific DNA binding
HVW55_12990	COG3135	benzoate transporter
HVW55_13000	COG0500	methyltransferase
HVW55_13005	COG1275	C4-dicarboxylate transporter malic acid transport protein
HVW55_13010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVW55_13015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVW55_13020	COG2841	Protein conserved in bacteria
HVW55_13030	COG5383	Protein conserved in bacteria
HVW55_13035	COG0583	DNA-binding transcription factor activity
HVW55_13040	COG0840	transmembrane signaling receptor activity
HVW55_13055	COG3038	cytochrome b561
HVW55_13060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HVW55_13065	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_13070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HVW55_13075	COG1643	Atp-dependent helicase
HVW55_13085	COG2453	phosphatase
HVW55_13085	COG0671	phosphoesterase, PA-phosphatase related
HVW55_13090	COG2267	carboxylic ester hydrolase activity
HVW55_13095	COG4589	Belongs to the CDS family
HVW55_13110	COG0667	Aldo Keto reductase
HVW55_13115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVW55_13120	COG3327	negative regulation of DNA-templated transcription, initiation
HVW55_13125	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HVW55_13130	COG0183	Belongs to the thiolase family
HVW55_13135	COG2050	protein possibly involved in aromatic compounds catabolism
HVW55_13140	COG1250	3-hydroxyacyl-CoA dehydrogenase
HVW55_13145	COG1024	Enoyl-CoA hydratase
HVW55_13150	COG1024	Enoyl-CoA hydratase
HVW55_13155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_13160	COG2151	metal-sulfur cluster biosynthetic enzyme
HVW55_13165	COG3396	Phenylacetate-CoA oxygenase
HVW55_13170	COG3460	Phenylacetate-CoA oxygenase
HVW55_13175	COG3396	Phenylacetate-CoA oxygenase
HVW55_13180	COG2030	dehydratase
HVW55_13180	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_13185	COG3733	amine oxidase
HVW55_13190	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_13195	COG2207	Transcriptional regulator
HVW55_13200	COG3784	Protein of unknown function (DUF1318)
HVW55_13210	COG2911	Protein conserved in bacteria
HVW55_13215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HVW55_13220	COG3187	Heat shock protein
HVW55_13225	COG3042	response to heat
HVW55_13230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HVW55_13230	COG0674	pyruvate-flavodoxin oxidoreductase activity
HVW55_13230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVW55_13230	COG1013	pyruvate-flavodoxin oxidoreductase activity
HVW55_13235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVW55_13240	COG0589	response to stress
HVW55_13260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVW55_13265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVW55_13270	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVW55_13305	COG1196	nuclear chromosome segregation
HVW55_13385	COG1475	DNA binding
HVW55_13390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVW55_13400	COG3772	lysozyme
HVW55_13415	COG3064	Membrane
HVW55_13455	COG1846	Transcriptional regulator
HVW55_13460	COG1484	DNA-dependent DNA replication
HVW55_13465	COG3756	Protein conserved in bacteria
HVW55_13475	COG4197	protein conserved in bacteria, prophage-related
HVW55_13510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_13515	COG3723	Recombinational DNA repair protein, rece pathway
HVW55_13535	COG0582	viral genome integration into host DNA
HVW55_13545	COG0513	Belongs to the DEAD box helicase family
HVW55_13555	COG3706	GGDEF domain
HVW55_13560	COG2840	Smr protein MutS2
HVW55_13565	COG0583	DNA-binding transcription factor activity
HVW55_13570	COG1473	amidohydrolase
HVW55_13575	COG1473	amidohydrolase
HVW55_13580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HVW55_13585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVW55_13590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVW55_13595	COG0589	response to stress
HVW55_13600	COG3182	Iron-regulated membrane protein
HVW55_13605	COG0668	transmembrane transport
HVW55_13610	COG4166	transmembrane transport
HVW55_13615	COG0583	DNA-binding transcription factor activity
HVW55_13620	COG1073	alpha beta
HVW55_13630	COG0702	epimerase
HVW55_13635	COG2866	Carboxypeptidase
HVW55_13640	COG4948	Mandelate Racemase Muconate Lactonizing
HVW55_13645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HVW55_13650	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HVW55_13660	COG3106	COG3106 Predicted ATPase
HVW55_13665	COG1609	Transcriptional regulator
HVW55_13675	COG3842	ATPase activity
HVW55_13680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVW55_13685	COG1554	hydrolase, family 65, central catalytic
HVW55_13690	COG0673	inositol 2-dehydrogenase activity
HVW55_13695	COG1082	Xylose isomerase domain protein TIM barrel
HVW55_13700	COG1063	alcohol dehydrogenase
HVW55_13705	COG0395	ABC-type sugar transport system, permease component
HVW55_13710	COG1175	transmembrane transport
HVW55_13715	COG1653	transport
HVW55_13720	COG0366	Alpha amylase catalytic
HVW55_13725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVW55_13735	COG1983	PspC domain protein
HVW55_13745	COG1842	Phage shock protein A
HVW55_13750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HVW55_13755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HVW55_13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HVW55_13765	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_13770	COG1917	Cupin 2, conserved barrel domain protein
HVW55_13770	COG1396	sequence-specific DNA binding
HVW55_13775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HVW55_13780	COG0174	glutamine synthetase
HVW55_13790	COG0531	amino acid
HVW55_13800	COG4166	transmembrane transport
HVW55_13805	COG4168	peptide transport system, permease
HVW55_13810	COG4171	peptide transport system, permease
HVW55_13815	COG4172	Belongs to the ABC transporter superfamily
HVW55_13820	COG4172	Belongs to the ABC transporter superfamily
HVW55_13825	COG2814	Major facilitator Superfamily
HVW55_13835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_13840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_13850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HVW55_13855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVW55_13855	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVW55_13870	COG5001	Diguanylate cyclase
HVW55_13880	COG1349	DNA-binding transcription factor activity
HVW55_13890	COG0023	Translation Initiation Factor
HVW55_13900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HVW55_13905	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HVW55_13910	COG0671	phosphoesterase, PA-phosphatase related
HVW55_13920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HVW55_13940	COG0583	DNA-binding transcription factor activity
HVW55_13945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVW55_13955	COG0616	signal peptide processing
HVW55_13960	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_13965	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HVW55_13970	COG1187	pseudouridine synthase activity
HVW55_13975	COG4907	membrane protein (DUF2207)
HVW55_13980	COG0009	L-threonylcarbamoyladenylate synthase
HVW55_13985	COG0613	PHP domain protein
HVW55_13995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVW55_14000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVW55_14000	COG0512	Glutamine amidotransferase of anthranilate synthase
HVW55_14005	COG0134	indole-3-glycerol-phosphate synthase activity
HVW55_14005	COG0135	phosphoribosylanthranilate isomerase activity
HVW55_14020	COG3729	General stress protein
HVW55_14025	COG3685	Protein conserved in bacteria
HVW55_14030	COG3685	Protein conserved in bacteria
HVW55_14035	COG3047	cAMP biosynthetic process
HVW55_14055	COG1607	acyl-coa hydrolase
HVW55_14060	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HVW55_14065	COG2350	Protein conserved in bacteria
HVW55_14070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVW55_14090	COG4608	Belongs to the ABC transporter superfamily
HVW55_14095	COG0444	Belongs to the ABC transporter superfamily
HVW55_14100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVW55_14105	COG0601	transmembrane transport
HVW55_14110	COG4166	transmembrane transport
HVW55_14115	COG2095	MarC family integral membrane protein
HVW55_14120	COG1454	alcohol dehydrogenase
HVW55_14120	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_14125	COG3385	transposase activity
HVW55_14140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVW55_14145	COG0745	RESPONSE REGULATOR receiver
HVW55_14150	COG1752	Esterase of the alpha-beta hydrolase superfamily
HVW55_14160	COG0788	formyltetrahydrofolate deformylase activity
HVW55_14190	COG2181	nitrate reductase activity
HVW55_14195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVW55_14200	COG1140	nitrate reductase beta subunit
HVW55_14205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVW55_14210	COG2223	nitrite transmembrane transporter activity
HVW55_14215	COG3850	Histidine kinase
HVW55_14220	COG2197	response regulator
HVW55_14225	COG4932	domain protein
HVW55_14230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HVW55_14235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HVW55_14240	COG4572	Cation transport regulator
HVW55_14245	COG0387	Pfam Sodium calcium exchanger
HVW55_14265	COG2912	Transglutaminase-like superfamily
HVW55_14270	COG3094	Invasion gene expression up-regulator, SirB
HVW55_14275	COG2890	protein-(glutamine-N5) methyltransferase activity
HVW55_14300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HVW55_14305	COG0659	secondary active sulfate transmembrane transporter activity
HVW55_14320	COG0012	GTP binding
HVW55_14325	COG3468	outer membrane autotransporter barrel domain protein
HVW55_14330	COG3284	Transcriptional regulator
HVW55_14335	COG2376	Dihydroxyacetone kinase
HVW55_14340	COG1461	Dihydroxyacetone kinase
HVW55_14345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_14345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVW55_14345	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HVW55_14365	COG1120	ATPase activity
HVW55_14370	COG0500	methyltransferase
HVW55_14375	COG0157	Belongs to the NadC ModD family
HVW55_14390	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HVW55_14400	COG1619	proteins homologs of microcin C7 resistance protein MccF
HVW55_14420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVW55_14430	COG2719	SpoVR family
HVW55_14445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HVW55_14450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HVW55_14455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HVW55_14470	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVW55_14495	COG2894	cell division
HVW55_14545	COG2200	EAL domain
HVW55_14565	COG2200	EAL domain
HVW55_14570	COG0789	Transcriptional regulator
HVW55_14575	COG5562	phage envelope protein
HVW55_14595	COG0538	isocitrate dehydrogenase activity
HVW55_14600	COG1187	pseudouridine synthase activity
HVW55_14620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HVW55_14630	COG2205	protein histidine kinase activity
HVW55_14635	COG2850	peptidyl-arginine hydroxylation
HVW55_14645	COG3842	ATPase activity
HVW55_14655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVW55_14660	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVW55_14860	COG4220	transposase activity
HVW55_14870	COG5562	phage envelope protein
HVW55_14895	COG2207	Transcriptional regulator
HVW55_14910	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HVW55_14915	COG1403	HNH endonuclease
HVW55_15000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_15010	COG0582	viral genome integration into host DNA
HVW55_15025	COG1177	transmembrane transport
HVW55_15030	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVW55_15035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HVW55_15045	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVW55_15050	COG1136	(ABC) transporter
HVW55_15055	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVW55_15060	COG4763	Acyl-transferase
HVW55_15065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HVW55_15070	COG1376	ErfK ybiS ycfS ynhG family protein
HVW55_15070	COG1388	LysM domain
HVW55_15080	COG1309	transcriptional regulator
HVW55_15085	COG3134	Outer membrane lipoprotein
HVW55_15090	COG1252	NADH dehydrogenase
HVW55_15105	COG0510	thiamine kinase activity
HVW55_15110	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HVW55_15115	COG5633	Lipoprotein
HVW55_15120	COG0537	adenosine 5'-monophosphoramidase activity
HVW55_15125	COG4773	Receptor
HVW55_15130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_15130	COG1263	PTS System
HVW55_15135	COG0084	hydrolase, TatD family'
HVW55_15140	COG0470	DNA polymerase III
HVW55_15150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HVW55_15155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVW55_15160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVW55_15170	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_15175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HVW55_15195	COG1399	metal-binding, possibly nucleic acid-binding protein
HVW55_15200	COG0424	maF-like protein
HVW55_15205	COG0564	pseudouridine synthase activity
HVW55_15210	COG1530	ribonuclease E activity
HVW55_15215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HVW55_15220	COG1256	bacterial-type flagellum assembly
HVW55_15225	COG1705	Flagellar rod assembly protein muramidase FlgJ
HVW55_15225	COG3951	Flagellar rod assembly protein muramidase FlgJ
HVW55_15240	COG4786	Flagellar basal body rod
HVW55_15245	COG4787	bacterial-type flagellum-dependent cell motility
HVW55_15250	COG1749	Flagellar hook protein flgE
HVW55_15255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HVW55_15260	COG1558	bacterial-type flagellum-dependent cell motility
HVW55_15265	COG1815	bacterial-type flagellum-dependent cell motility
HVW55_15270	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HVW55_15275	COG2747	anti-sigma28 factor FlgM
HVW55_15280	COG3418	PFAM FlgN family protein
HVW55_15285	COG0728	peptidoglycan biosynthetic process
HVW55_15290	COG0673	inositol 2-dehydrogenase activity
HVW55_15300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVW55_15310	COG2999	glutathione oxidoreductase activity
HVW55_15345	COG3038	cytochrome b561
HVW55_15350	COG2353	YceI-like domain
HVW55_15360	COG1560	Kdo2-lipid A biosynthetic process
HVW55_15375	COG5645	(Lipo)protein
HVW55_15380	COG2943	transferase activity, transferring hexosyl groups
HVW55_15395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVW55_15400	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVW55_15425	COG2197	response regulator
HVW55_15440	COG1462	curli production assembly transport component CsgG
HVW55_15450	COG3381	protein complex oligomerization
HVW55_15515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVW55_15520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HVW55_15530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HVW55_15540	COG0736	holo-[acyl-carrier-protein] synthase activity
HVW55_15545	COG2831	hemolysin activation secretion protein
HVW55_15550	COG3210	domain, Protein
HVW55_15560	COG3539	Fimbrial protein
HVW55_15570	COG3188	usher protein
HVW55_15580	COG3121	Chaperone
HVW55_15585	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_15590	COG3710	Transcriptional regulator
HVW55_15600	COG2200	EAL domain
HVW55_15605	COG3706	GGDEF domain
HVW55_15610	COG0457	Tetratricopeptide repeat
HVW55_15615	COG0726	polysaccharide deacetylase
HVW55_15615	COG1649	PFAM Uncharacterised BCR, COG1649
HVW55_15620	COG1215	transferase activity, transferring glycosyl groups
HVW55_15625	COG3658	cytochrome
HVW55_15630	COG1702	phosphate starvation-inducible protein PhoH
HVW55_15640	COG2822	iron ion transport
HVW55_15655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVW55_15665	COG0506	proline dehydrogenase activity
HVW55_15665	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVW55_15665	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVW55_15670	COG1309	transcriptional regulator
HVW55_15705	COG2233	PERMEase
HVW55_15710	COG3729	General stress protein
HVW55_15750	COG0243	molybdopterin cofactor binding
HVW55_15755	COG3005	denitrification pathway
HVW55_15760	COG0745	RESPONSE REGULATOR receiver
HVW55_15765	COG1879	ABC-type sugar transport system periplasmic component
HVW55_15770	COG2198	Histidine kinase
HVW55_15770	COG0784	Response regulator, receiver
HVW55_15770	COG2205	protein histidine kinase activity
HVW55_15775	COG0348	domain, Protein
HVW55_15795	COG1278	Cold shock
HVW55_15800	COG1278	Cold shock
HVW55_15820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVW55_15830	COG3385	transposase activity
HVW55_15840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HVW55_15845	COG3206	protein involved in exopolysaccharide biosynthesis
HVW55_15845	COG0489	protein tyrosine kinase activity
HVW55_15860	COG1294	oxidase, subunit
HVW55_15865	COG1271	oxidase subunit
HVW55_15870	COG1773	rubredoxin
HVW55_15875	COG1999	signal sequence binding
HVW55_15880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVW55_15885	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HVW55_15890	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVW55_15895	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVW55_15905	COG0670	Belongs to the BI1 family
HVW55_15910	COG2920	part of a sulfur-relay system
HVW55_15915	COG1254	Belongs to the acylphosphatase family
HVW55_15930	COG1832	CoA-binding protein
HVW55_15945	COG0210	DNA helicase
HVW55_15950	COG3304	Inner membrane component domain
HVW55_15955	COG1289	transmembrane transporter activity
HVW55_15960	COG3070	regulator of competence-specific genes
HVW55_15980	COG1067	ATP-dependent peptidase activity
HVW55_15990	COG3130	regulation of translation
HVW55_15995	COG3009	Protein conserved in bacteria
HVW55_16000	COG3008	intermembrane lipid transfer
HVW55_16000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVW55_16005	COG2995	paraquat-inducible protein a
HVW55_16010	COG0488	(ABC) transporter
HVW55_16020	COG3217	Mosc domain protein beta barrel domain protein
HVW55_16020	COG0633	Ferredoxin
HVW55_16035	COG3121	Chaperone
HVW55_16040	COG3539	Fimbrial protein
HVW55_16045	COG3539	Fimbrial protein
HVW55_16050	COG3539	Fimbrial protein
HVW55_16055	COG3188	usher protein
HVW55_16060	COG3121	Chaperone
HVW55_16065	COG3539	Fimbrial protein
HVW55_16070	COG0431	NADPH-dependent FMN reductase
HVW55_16075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HVW55_16085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVW55_16090	COG1116	anion transmembrane transporter activity
HVW55_16095	COG0308	aminopeptidase N
HVW55_16115	COG1448	Aminotransferase
HVW55_16120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HVW55_16125	COG3108	Peptidase M15
HVW55_16130	COG2989	Protein conserved in bacteria
HVW55_16140	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HVW55_16150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HVW55_16155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HVW55_16160	COG3173	Aminoglycoside phosphotransferase
HVW55_16175	COG3214	Protein conserved in bacteria
HVW55_16185	COG1132	(ABC) transporter
HVW55_16190	COG2333	competence protein COMEC
HVW55_16190	COG0658	competence protein
HVW55_16200	COG0539	negative regulation of cytoplasmic translation
HVW55_16210	COG0501	Belongs to the peptidase M48B family
HVW55_16215	COG3385	transposase activity
HVW55_16230	COG2323	membrane
HVW55_16235	COG1944	ATP diphosphatase activity
HVW55_16240	COG2116	formate transmembrane transporter activity
HVW55_16245	COG1882	Formate acetyltransferase
HVW55_16300	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVW55_16395	COG4695	Portal protein
HVW55_16475	COG4974	Belongs to the 'phage' integrase family
HVW55_16480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVW55_16490	COG0531	amino acid
HVW55_16500	COG1335	isochorismatase
HVW55_16505	COG3302	dmso reductase anchor subunit
HVW55_16510	COG0437	4 iron, 4 sulfur cluster binding
HVW55_16515	COG0243	molybdopterin cofactor binding
HVW55_16525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HVW55_16540	COG1522	sequence-specific DNA binding
HVW55_16545	COG0492	ferredoxin-NADP+ reductase activity
HVW55_16550	COG4988	ABC transporter
HVW55_16555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HVW55_16575	COG0542	response to heat
HVW55_16585	COG1278	Cold shock
HVW55_16590	COG1136	(ABC) transporter
HVW55_16590	COG0577	efflux transmembrane transporter activity
HVW55_16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_16600	COG2990	Protein conserved in bacteria
HVW55_16605	COG3593	DNA synthesis involved in DNA repair
HVW55_16610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HVW55_16615	COG2431	L-lysine efflux transmembrane transporter activity
HVW55_16625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVW55_16630	COG0028	Belongs to the TPP enzyme family
HVW55_16635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HVW55_16640	COG0702	epimerase
HVW55_16645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVW55_16650	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVW55_16670	COG1126	abc transporter atp-binding protein
HVW55_16675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_16680	COG4215	(ABC) transporter
HVW55_16685	COG4160	amino acid transport
HVW55_16690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_16720	COG1177	transmembrane transport
HVW55_16725	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVW55_16730	COG3842	ATPase activity
HVW55_16735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVW55_16750	COG0778	Nitroreductase
HVW55_16760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVW55_16780	COG3226	Transcriptional regulator
HVW55_16785	COG0738	Major facilitator superfamily
HVW55_16790	COG0561	phosphatase activity
HVW55_16800	COG2814	Major facilitator Superfamily
HVW55_16805	COG0671	phosphoesterase, PA-phosphatase related
HVW55_16810	COG1349	DNA-binding transcription factor activity
HVW55_16815	COG1686	Belongs to the peptidase S11 family
HVW55_16820	COG0625	glutathione transferase activity
HVW55_16825	COG2133	pyrroloquinoline quinone binding
HVW55_16850	COG2199	diguanylate cyclase activity
HVW55_16855	COG2200	EAL domain
HVW55_16870	COG0747	negative chemotaxis
HVW55_16880	COG1446	asparaginase
HVW55_16885	COG0303	'Molybdopterin
HVW55_16890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVW55_16895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVW55_16900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVW55_16905	COG1882	Formate acetyltransferase
HVW55_16910	COG0561	phosphatase activity
HVW55_16920	COG0488	(ABC) transporter
HVW55_16925	COG1376	ErfK ybiS ycfS ynhG family protein
HVW55_16930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HVW55_16935	COG1321	iron dependent repressor
HVW55_16945	COG2194	sulfuric ester hydrolase activity
HVW55_16950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HVW55_16960	COG5006	permease, DMT superfamily
HVW55_16970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_16975	COG0765	amino acid transport
HVW55_16980	COG1126	abc transporter atp-binding protein
HVW55_16985	COG0668	transmembrane transport
HVW55_17000	COG4774	siderophore transport
HVW55_17010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVW55_17020	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVW55_17025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVW55_17030	COG1199	ATP-dependent helicase activity
HVW55_17045	COG0513	Belongs to the DEAD box helicase family
HVW55_17050	COG1309	transcriptional regulator
HVW55_17060	COG1131	(ABC) transporter
HVW55_17065	COG0842	Transport permease protein
HVW55_17070	COG0842	Transport permease protein
HVW55_17080	COG3568	Endonuclease Exonuclease Phosphatase
HVW55_17085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVW55_17090	COG0392	lysyltransferase activity
HVW55_17095	COG0670	Belongs to the BI1 family
HVW55_17100	COG0670	Belongs to the BI1 family
HVW55_17105	COG0314	molybdopterin synthase activity
HVW55_17110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HVW55_17120	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVW55_17130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HVW55_17140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVW55_17145	COG2226	methyltransferase
HVW55_17160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HVW55_17165	COG1881	PFAM PEBP family protein
HVW55_17170	COG4677	pectinesterase activity
HVW55_17175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HVW55_17180	COG0471	metal ion transport
HVW55_17185	COG2828	Protein conserved in bacteria
HVW55_17190	COG0583	DNA-binding transcription factor activity
HVW55_17200	COG0561	phosphatase activity
HVW55_17210	COG4149	molybdate abc transporter
HVW55_17215	COG0725	ABC transporter, periplasmic molybdate-binding protein
HVW55_17225	COG2005	Transcriptional regulator
HVW55_17225	COG3585	molybdate ion transport
HVW55_17230	COG1119	ATPase activity
HVW55_17235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HVW55_17240	COG1085	galactose-1-phosphate uridylyltransferase
HVW55_17250	COG2017	converts alpha-aldose to the beta-anomer
HVW55_17260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVW55_17270	COG1230	cation diffusion facilitator family transporter
HVW55_17275	COG3201	nicotinamide mononucleotide transporter
HVW55_17280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HVW55_17320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HVW55_17325	COG2885	chlorophyll binding
HVW55_17335	COG3064	Membrane
HVW55_17340	COG0848	biopolymer transport protein
HVW55_17345	COG0811	peptide transport
HVW55_17350	COG0824	Thioesterase
HVW55_17355	COG3790	cyd operon protein YbgE
HVW55_17360	COG4890	Cyd operon protein YbgT
HVW55_17365	COG1294	oxidase, subunit
HVW55_17370	COG1271	oxidase subunit
HVW55_17385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVW55_17395	COG4865	methylaspartate mutase activity
HVW55_17400	COG3799	methylaspartate ammonia-lyase activity
HVW55_17415	COG1301	dicarboxylic acid transport
HVW55_17420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_17420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_17425	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HVW55_17430	COG0583	DNA-binding transcription factor activity
HVW55_17435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVW55_17445	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVW55_17450	COG0567	Dehydrogenase, E1 component
HVW55_17455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVW55_17460	COG1053	succinate dehydrogenase
HVW55_17465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HVW55_17470	COG2009	succinate dehydrogenase
HVW55_17480	COG0372	Belongs to the citrate synthase family
HVW55_17485	COG3539	Fimbrial protein
HVW55_17490	COG3188	usher protein
HVW55_17495	COG3121	Chaperone
HVW55_17500	COG3539	Fimbrial protein
HVW55_17505	COG3180	Ammonia monooxygenase
HVW55_17520	COG1984	allophanate hydrolase subunit 2
HVW55_17525	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HVW55_17530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HVW55_17540	COG0415	Belongs to the DNA photolyase family
HVW55_17545	COG3272	Protein of unknown function (DUF1722)
HVW55_17575	COG2205	protein histidine kinase activity
HVW55_17580	COG0745	RESPONSE REGULATOR receiver
HVW55_17590	COG1982	Orn Lys Arg decarboxylase major
HVW55_17595	COG0531	amino acid
HVW55_17600	COG0033	Phosphoglucomutase
HVW55_17605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HVW55_17610	COG0596	Alpha beta hydrolase
HVW55_17620	COG0716	FMN binding
HVW55_17630	COG0735	belongs to the Fur family
HVW55_17650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_17650	COG2190	(PTS) system
HVW55_17650	COG1263	PTS System
HVW55_17660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVW55_17665	COG1846	Transcriptional regulator
HVW55_17665	COG1940	carbohydrate kinase activity
HVW55_17670	COG0647	UMP catabolic process
HVW55_17675	COG0367	asparagine synthase
HVW55_17715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVW55_17725	COG1702	phosphate starvation-inducible protein PhoH
HVW55_17735	COG4535	Mg2 and Co2 transporter CorC
HVW55_17740	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HVW55_17745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVW55_17750	COG0765	amino acid transport
HVW55_17755	COG0765	amino acid transport
HVW55_17760	COG1126	abc transporter atp-binding protein
HVW55_17770	COG0443	Heat shock 70 kDa protein
HVW55_17775	COG2214	Heat shock protein DnaJ domain protein
HVW55_17785	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVW55_17790	COG2214	Heat shock protein DnaJ domain protein
HVW55_17800	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVW55_17805	COG2888	peptidyl-tyrosine sulfation
HVW55_17820	COG1466	dna polymerase III delta subunit
HVW55_17830	COG0406	alpha-ribazole phosphatase activity
HVW55_17835	COG0799	negative regulation of ribosome biogenesis
HVW55_17845	COG0768	penicillin binding
HVW55_17850	COG0772	Belongs to the SEDS family
HVW55_17855	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVW55_17860	COG1686	Belongs to the peptidase S11 family
HVW55_17875	COG0583	DNA-binding transcription factor activity
HVW55_17885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVW55_17890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVW55_17910	COG3069	C4-dicarboxylate transmembrane transporter activity
HVW55_17915	COG4565	transcriptional regulatory protein
HVW55_17920	COG3290	protein histidine kinase activity
HVW55_17925	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HVW55_17935	COG2301	Belongs to the HpcH HpaI aldolase family
HVW55_17940	COG3051	citrate lyase alpha subunit
HVW55_17955	COG0471	metal ion transport
HVW55_17960	COG3719	Belongs to the RNase T2 family
HVW55_17965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVW55_17970	COG1063	alcohol dehydrogenase
HVW55_17975	COG0589	response to stress
HVW55_17980	COG3634	alkyl hydroperoxide reductase activity
HVW55_17985	COG0450	alkyl hydroperoxide reductase
HVW55_17990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVW55_17995	COG0583	DNA-binding transcription factor activity
HVW55_18000	COG3969	phosphoadenosine phosphosulfate
HVW55_18005	COG1475	DNA binding
HVW55_18010	COG0436	Aminotransferase
HVW55_18015	COG0371	Dehydrogenase
HVW55_18020	COG2879	small protein
HVW55_18120	COG2050	protein possibly involved in aromatic compounds catabolism
HVW55_18125	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_18130	COG1535	isochorismatase
HVW55_18130	COG3433	isochorismatase activity
HVW55_18135	COG1021	2,3-dihydroxybenzoate-AMP ligase
HVW55_18140	COG1169	isochorismate synthase
HVW55_18145	COG4592	Periplasmic binding protein
HVW55_18155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_18160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_18165	COG1120	ATPase activity
HVW55_18170	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVW55_18175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HVW55_18175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HVW55_18180	COG3251	PFAM MbtH domain protein
HVW55_18185	COG2382	esterase
HVW55_18190	COG4771	TonB-dependent receptor
HVW55_18195	COG2977	Belongs to the P-Pant transferase superfamily
HVW55_18225	COG2315	Protein conserved in bacteria
HVW55_18230	COG0778	Nitroreductase
HVW55_18235	COG0668	transmembrane transport
HVW55_18240	COG1113	amino acid transport
HVW55_18245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_18250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_18255	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_18260	COG1538	Outer membrane efflux protein
HVW55_18265	COG0745	RESPONSE REGULATOR receiver
HVW55_18270	COG5002	protein histidine kinase activity
HVW55_18275	COG1215	transferase activity, transferring glycosyl groups
HVW55_18280	COG4783	chaperone-mediated protein folding
HVW55_18300	COG2197	response regulator
HVW55_18305	COG3539	Fimbrial protein
HVW55_18310	COG3539	Fimbrial protein
HVW55_18315	COG3188	usher protein
HVW55_18320	COG3121	Chaperone
HVW55_18325	COG3539	Fimbrial protein
HVW55_18335	COG2501	S4 domain
HVW55_18340	COG1988	membrane-bound metal-dependent
HVW55_18350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HVW55_18360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HVW55_18365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HVW55_18370	COG0549	Belongs to the carbamate kinase family
HVW55_18380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVW55_18385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVW55_18390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVW55_18395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HVW55_18400	COG3257	ureidoglycine aminohydrolase activity
HVW55_18405	COG1929	Belongs to the glycerate kinase type-1 family
HVW55_18410	COG2233	PERMEase
HVW55_18420	COG1953	Uracil, thiamine, allantoin
HVW55_18425	COG2084	Dehydrogenase
HVW55_18430	COG3622	Belongs to the hyi family
HVW55_18435	COG3960	tartronate-semialdehyde synthase activity
HVW55_18440	COG1414	Transcriptional regulator
HVW55_18450	COG0583	DNA-binding transcription factor activity
HVW55_18475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HVW55_18480	COG4181	ATPase activity
HVW55_18485	COG2755	lipolytic protein G-D-S-L family
HVW55_18490	COG0300	oxidoreductase activity
HVW55_18495	COG3118	belongs to the thioredoxin family
HVW55_18500	COG0390	transport system, permease component
HVW55_18505	COG4619	ABC transporter
HVW55_18510	COG0330	HflC and HflK could
HVW55_18515	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVW55_18535	COG0789	Transcriptional regulator
HVW55_18560	COG0531	amino acid
HVW55_18570	COG2217	Heavy metal translocating P-type atpase
HVW55_18575	COG3093	addiction module antidote protein HigA
HVW55_18580	COG3735	TraB family
HVW55_18585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVW55_18590	COG0737	Belongs to the 5'-nucleotidase family
HVW55_18595	COG2223	nitrite transmembrane transporter activity
HVW55_18600	COG4651	solute:proton antiporter activity
HVW55_18600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVW55_18610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_18645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HVW55_18655	COG2832	Protein of unknown function (DUF454)
HVW55_18660	COG3923	Primosomal replication protein n
HVW55_18670	COG1196	nuclear chromosome segregation
HVW55_18670	COG3264	Mechanosensitive ion channel
HVW55_18675	COG1309	transcriptional regulator
HVW55_18680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVW55_18685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVW55_18700	COG0110	maltose O-acetyltransferase activity
HVW55_18710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HVW55_18715	COG5507	3-demethylubiquinone-9 3-methyltransferase
HVW55_18725	COG3695	enzyme binding
HVW55_18730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HVW55_18735	COG1946	Acyl-CoA thioesterase
HVW55_18740	COG0004	ammonium transporteR
HVW55_18745	COG0347	Belongs to the P(II) protein family
HVW55_18750	COG1132	(ABC) transporter
HVW55_18755	COG1132	(ABC) transporter
HVW55_18760	COG1522	sequence-specific DNA binding
HVW55_18770	COG4533	DNA binding
HVW55_18780	COG0824	Thioesterase
HVW55_18785	COG1555	photosystem II stabilization
HVW55_18790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVW55_18795	COG0776	regulation of translation
HVW55_18800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HVW55_18820	COG0271	Belongs to the BolA IbaG family
HVW55_18825	COG3056	Lipoprotein
HVW55_18830	COG2223	nitrite transmembrane transporter activity
HVW55_18835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HVW55_18840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HVW55_18845	COG1845	cytochrome c oxidase, subunit III
HVW55_18850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HVW55_18860	COG2814	Major facilitator Superfamily
HVW55_18870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HVW55_18875	COG0693	protein deglycase activity
HVW55_18890	COG0142	geranyltranstransferase activity
HVW55_18900	COG0667	Aldo Keto reductase
HVW55_18910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HVW55_18915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HVW55_18930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVW55_18930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVW55_18940	COG4238	major outer membrane lipoprotein
HVW55_18945	COG3248	Nucleoside-binding outer membrane protein
HVW55_18950	COG1403	HNH endonuclease
HVW55_18960	COG3609	addiction module antidote protein, CC2985 family
HVW55_18965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVW55_18970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVW55_18975	COG1862	Preprotein translocase
HVW55_19000	COG0366	Alpha amylase catalytic
HVW55_19005	COG1113	amino acid transport
HVW55_19010	COG1114	Component of the transport system for branched-chain amino acids
HVW55_19015	COG5002	protein histidine kinase activity
HVW55_19020	COG0745	RESPONSE REGULATOR receiver
HVW55_19025	COG0420	3'-5' exonuclease activity
HVW55_19030	COG0419	ATPase involved in DNA repair
HVW55_19035	COG2814	Major facilitator Superfamily
HVW55_19040	COG1940	carbohydrate kinase activity
HVW55_19065	COG4126	flavin adenine dinucleotide binding
HVW55_19085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HVW55_19090	COG3706	GGDEF domain
HVW55_19100	COG1785	Belongs to the alkaline phosphatase family
HVW55_19115	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVW55_19135	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HVW55_19140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVW55_19145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVW55_19150	COG3468	outer membrane autotransporter barrel domain protein
HVW55_19155	COG0113	porphobilinogen synthase activity
HVW55_19160	COG2175	clavaminate synthase activity
HVW55_19165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVW55_19175	COG4521	taurine ABC transporter
HVW55_19190	COG2271	Major facilitator Superfamily
HVW55_19195	COG1840	ABC-type Fe3 transport system, periplasmic component
HVW55_19205	COG3842	ATPase activity
HVW55_19225	COG3122	Protein conserved in bacteria
HVW55_19230	COG2814	Major facilitator Superfamily
HVW55_19250	COG0596	Alpha beta hydrolase
HVW55_19265	COG1414	Transcriptional regulator
HVW55_19270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HVW55_19280	COG1609	Transcriptional regulator
HVW55_19290	COG2223	nitrite transmembrane transporter activity
HVW55_19295	COG0110	maltose O-acetyltransferase activity
HVW55_19300	COG2807	transmembrane transport
HVW55_19310	COG0288	reversible hydration of carbon dioxide
HVW55_19315	COG0583	DNA-binding transcription factor activity
HVW55_19320	COG0402	S-adenosylhomocysteine deaminase activity
HVW55_19325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HVW55_19330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVW55_19335	COG2079	MmgE PrpD family protein
HVW55_19340	COG0372	Belongs to the citrate synthase family
HVW55_19345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HVW55_19350	COG3829	transcription factor binding
HVW55_19360	COG1280	lysine exporter protein (LysE YggA)
HVW55_19375	COG1064	alcohol dehydrogenase
HVW55_19385	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_19390	COG1129	ABC transporter
HVW55_19395	COG1879	ABC-type sugar transport system periplasmic component
HVW55_19405	COG0402	S-adenosylhomocysteine deaminase activity
HVW55_19410	COG0549	Belongs to the carbamate kinase family
HVW55_19420	COG1304	FMN binding
HVW55_19425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVW55_19435	COG0666	response to abiotic stimulus
HVW55_19445	COG0583	DNA-binding transcription factor activity
HVW55_19450	COG2771	luxR family
HVW55_19450	COG2200	EAL domain
HVW55_19460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HVW55_19480	COG0582	viral genome integration into host DNA
HVW55_19485	COG2771	luxR family
HVW55_19485	COG2200	EAL domain
HVW55_19500	COG3468	outer membrane autotransporter barrel domain protein
HVW55_19510	COG1556	Lactate utilization protein
HVW55_19515	COG1139	Iron-sulfur cluster binding protein
HVW55_19520	COG0247	lactate metabolic process
HVW55_19525	COG2207	Transcriptional regulator
HVW55_19530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVW55_19540	COG3059	membrane
HVW55_19545	COG0656	L-ascorbic acid biosynthetic process
HVW55_19550	COG3708	Transcriptional regulator
HVW55_19550	COG2207	Transcriptional regulator
HVW55_19555	COG1388	LysM domain
HVW55_19560	COG0656	L-ascorbic acid biosynthetic process
HVW55_19565	COG0667	Aldo Keto reductase
HVW55_19575	COG0583	DNA-binding transcription factor activity
HVW55_19580	COG1073	alpha beta
HVW55_19585	COG1902	pentaerythritol trinitrate reductase activity
HVW55_19625	COG3188	usher protein
HVW55_19635	COG3121	Chaperone
HVW55_19640	COG0727	PFAM Uncharacterised protein family (UPF0153)
HVW55_19645	COG3477	response to acidic pH
HVW55_19650	COG2080	2 iron, 2 sulfur cluster binding
HVW55_19655	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVW55_19660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVW55_19665	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HVW55_19680	COG0583	DNA-binding transcription factor activity
HVW55_19690	COG4221	oxidoreductase activity
HVW55_19695	COG0583	DNA-binding transcription factor activity
HVW55_19710	COG3423	Transcriptional regulator
HVW55_19830	COG0582	viral genome integration into host DNA
HVW55_19850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVW55_19870	COG2195	Cleaves the N-terminal amino acid of tripeptides
HVW55_19875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVW55_19880	COG1690	Belongs to the RtcB family
HVW55_19885	COG0454	-acetyltransferase
HVW55_19905	COG1943	Transposase
HVW55_19910	COG0791	NLP P60 protein
HVW55_19915	COG3077	Addiction module antitoxin, RelB DinJ family
HVW55_19920	COG3041	Addiction module toxin RelE StbE family
HVW55_19925	COG3034	peptidoglycan biosynthetic process
HVW55_19930	COG0121	glutamine amidotransferase
HVW55_19940	COG1960	acyl-CoA dehydrogenase activity
HVW55_19950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVW55_19960	COG5433	transposase activity
HVW55_19985	COG3436	PFAM IS66 Orf2 family protein
HVW55_19990	COG4372	Transposase
HVW55_20000	COG3501	Rhs element vgr protein
HVW55_20115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVW55_20125	COG2226	methyltransferase
HVW55_20135	COG0741	lytic transglycosylase activity
HVW55_20135	COG1388	LysM domain
HVW55_20140	COG2226	methyltransferase
HVW55_20150	COG0583	DNA-binding transcription factor activity
HVW55_20155	COG0656	L-ascorbic acid biosynthetic process
HVW55_20190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVW55_20195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HVW55_20200	COG2011	ABC-type metal ion transport system permease component
HVW55_20205	COG1464	Belongs to the NlpA lipoprotein family
HVW55_20215	COG1720	tRNA m6t6A37 methyltransferase activity
HVW55_20225	COG0791	NLP P60 protein
HVW55_20230	COG3015	lipoprotein NlpE involved in copper resistance
HVW55_20235	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVW55_20240	COG4681	YaeQ
HVW55_20250	COG4568	rho-dependent transcription termination
HVW55_20255	COG0037	tRNA processing
HVW55_20260	COG0346	lactoylglutathione lyase activity
HVW55_20275	COG0587	DNA-directed DNA polymerase activity
HVW55_20300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HVW55_20305	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HVW55_20315	COG0750	zinc metalloprotease
HVW55_20320	COG0575	Belongs to the CDS family
HVW55_20325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HVW55_20330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HVW55_20355	COG0024	Methionine aminopeptidase
HVW55_20375	COG3835	regulator
HVW55_20380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVW55_20395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVW55_20400	COG2860	membrane
HVW55_20425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVW55_20430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVW55_20435	COG1120	ATPase activity
HVW55_20440	COG4774	siderophore transport
HVW55_20445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HVW55_20450	COG1643	Atp-dependent helicase
HVW55_20455	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HVW55_20465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVW55_20475	COG0617	tRNA 3'-terminal CCA addition
HVW55_20480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HVW55_20490	COG3121	Chaperone
HVW55_20495	COG3188	usher protein
HVW55_20500	COG3539	Fimbrial protein
HVW55_20505	COG3539	Fimbrial protein
HVW55_20535	COG5464	transposase or invertase
HVW55_20545	COG0726	polysaccharide deacetylase
HVW55_20550	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_20555	COG0842	Transport permease protein
HVW55_20560	COG1131	(ABC) transporter
HVW55_20565	COG0288	reversible hydration of carbon dioxide
HVW55_20570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HVW55_20575	COG4993	Dehydrogenase
HVW55_20580	COG2132	Multicopper oxidase
HVW55_20605	COG1049	propionate catabolic process, 2-methylcitrate cycle
HVW55_20610	COG3064	Membrane
HVW55_20615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVW55_20620	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVW55_20625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HVW55_20630	COG2186	Transcriptional regulator
HVW55_20640	COG3725	Membrane protein required for beta-lactamase induction
HVW55_20645	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVW55_20650	COG0157	Belongs to the NadC ModD family
HVW55_20655	COG4969	Belongs to the N-Me-Phe pilin family
HVW55_20660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVW55_20665	COG1459	type II secretion system
HVW55_20680	COG0237	dephospho-CoA kinase activity
HVW55_20695	COG0494	nUDIX hydrolase
HVW55_20715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HVW55_20720	COG0849	cell division
HVW55_20725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HVW55_20730	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVW55_20745	COG0772	Belongs to the SEDS family
HVW55_20750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HVW55_20760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HVW55_20765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HVW55_20770	COG0768	penicillin binding
HVW55_20775	COG3116	cell division
HVW55_20790	COG1609	Transcriptional regulator
HVW55_20800	COG0440	acetolactate synthase activity
HVW55_20805	COG0028	Belongs to the TPP enzyme family
HVW55_20815	COG0583	DNA-binding transcription factor activity
HVW55_20860	COG4143	(ABC) transporter
HVW55_20865	COG1178	ABC-type Fe3 transport system permease component
HVW55_20870	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HVW55_20875	COG0586	Pfam SNARE associated Golgi protein
HVW55_20880	COG4977	sequence-specific DNA binding
HVW55_20885	COG1069	ribulokinase activity
HVW55_20895	COG0235	Class ii aldolase
HVW55_20900	COG0417	DNA replication proofreading
HVW55_20910	COG0564	pseudouridine synthase activity
HVW55_20920	COG1357	PFAM Pentapeptide repeats (8 copies)
HVW55_20925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HVW55_20930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HVW55_20935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVW55_20970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HVW55_20985	COG2271	Major facilitator Superfamily
HVW55_20990	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVW55_20995	COG0644	oxidoreductase
HVW55_21045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HVW55_21050	COG0505	Belongs to the CarA family
HVW55_21070	COG1047	Peptidyl-prolyl cis-trans
HVW55_21085	COG0196	riboflavin kinase activity
HVW55_21110	COG3121	Chaperone
HVW55_21115	COG3188	usher protein
HVW55_21125	COG0583	DNA-binding transcription factor activity
HVW55_21155	COG4735	regulation of single-species biofilm formation
HVW55_21160	COG1584	GPR1 FUN34 yaaH family protein
HVW55_21165	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVW55_21170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVW55_21175	COG1115	amino acid carrier protein
HVW55_21190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HVW55_21200	COG0527	aspartate kinase activity
HVW55_21200	COG0460	homoserine dehydrogenase
HVW55_21210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HVW55_21220	COG0745	RESPONSE REGULATOR receiver
HVW55_21225	COG4452	Inner membrane protein CreD
HVW55_21230	COG2205	protein histidine kinase activity
HVW55_21235	COG0745	RESPONSE REGULATOR receiver
HVW55_21240	COG3045	CreA protein
HVW55_21245	COG3708	Transcriptional regulator
HVW55_21245	COG2207	Transcriptional regulator
HVW55_21265	COG0741	lytic transglycosylase activity
HVW55_21270	COG0488	(ABC) transporter
HVW55_21275	COG0583	DNA-binding transcription factor activity
HVW55_21285	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_21300	COG1902	pentaerythritol trinitrate reductase activity
HVW55_21305	COG3172	ATPase kinase involved in NAD metabolism
HVW55_21305	COG1056	cytidyltransferase-related domain
HVW55_21310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HVW55_21315	COG0560	Phosphoserine phosphatase
HVW55_21320	COG3726	membrane protein affecting hemolysin expression
HVW55_21355	COG1328	CTP reductase activity
HVW55_21360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVW55_21365	COG0084	hydrolase, TatD family'
HVW55_21370	COG4667	esterase of the alpha-beta hydrolase superfamily
HVW55_21380	COG2823	Periplasmic or secreted lipoprotein
HVW55_21390	COG1011	Hydrolase
HVW55_21395	COG0456	acetyltransferase
HVW55_21400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HVW55_21430	COG4114	ferric iron reductase
HVW55_21435	COG2197	response regulator
HVW55_21440	COG2197	response regulator
HVW55_21445	COG2966	Psort location CytoplasmicMembrane, score
HVW55_21460	COG1484	DNA-dependent DNA replication
HVW55_21475	COG1063	alcohol dehydrogenase
HVW55_21485	COG2271	Major facilitator Superfamily
HVW55_21490	COG0840	transmembrane signaling receptor activity
HVW55_21495	COG1846	Transcriptional regulator
HVW55_21500	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVW55_21505	COG1012	belongs to the aldehyde dehydrogenase family
HVW55_21510	COG3384	dioxygenase
HVW55_21520	COG3971	2-oxopent-4-enoate hydratase activity
HVW55_21540	COG2368	4-hydroxyphenylacetate
HVW55_21545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVW55_21550	COG1966	Carbon starvation protein
HVW55_21555	COG2879	small protein
HVW55_21560	COG0523	cobalamin synthesis protein
HVW55_21570	COG5457	Domain of unknown function (DUF1127)
HVW55_21575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HVW55_21585	COG2814	Major facilitator Superfamily
HVW55_21590	COG2733	membrane
HVW55_21595	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HVW55_21600	COG1924	4 iron, 4 sulfur cluster binding
HVW55_21615	COG3204	pilus organization
HVW55_21620	COG0477	Major facilitator Superfamily
HVW55_21625	COG1470	cell adhesion involved in biofilm formation
HVW55_21625	COG1388	LysM domain
HVW55_21635	COG3366	ferrous iron transmembrane transporter activity
HVW55_21640	COG0700	Nucleoside recognition
HVW55_21645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVW55_21650	COG0583	DNA-binding transcription factor activity
HVW55_21670	COG2186	Transcriptional regulator
HVW55_21675	COG0246	Mannitol dehydrogenase
HVW55_21685	COG2610	gluconate transmembrane transporter activity
HVW55_21690	COG3539	Fimbrial protein
HVW55_21695	COG3539	Fimbrial protein
HVW55_21700	COG3539	Fimbrial protein
HVW55_21705	COG3188	usher protein
HVW55_21710	COG3121	Chaperone
HVW55_21715	COG3539	Fimbrial protein
HVW55_21720	COG3539	Fimbrial protein
HVW55_21725	COG4974	Belongs to the 'phage' integrase family
HVW55_21730	COG0582	viral genome integration into host DNA
HVW55_21735	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HVW55_21740	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HVW55_21755	COG0210	DNA helicase
HVW55_21760	COG1111	helicase
HVW55_21760	COG1205	dead DEAH box helicase
HVW55_21770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HVW55_21830	COG0433	COG0433 Predicted ATPase
HVW55_21835	COG0795	lipopolysaccharide-transporting ATPase activity
HVW55_21840	COG0795	lipopolysaccharide-transporting ATPase activity
HVW55_21850	COG2927	DNA polymerase III (CHI subunit)
HVW55_21860	COG4269	membrane
HVW55_21865	COG0456	acetyltransferase
HVW55_21870	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HVW55_21885	COG2731	YhcH YjgK YiaL family protein
HVW55_21890	COG1309	transcriptional regulator
HVW55_21895	COG1028	Short-chain dehydrogenase reductase Sdr
HVW55_21900	COG0251	oxidation-reduction process
HVW55_21920	COG0251	oxidation-reduction process
HVW55_21925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HVW55_21935	COG1609	Transcriptional regulator
HVW55_21940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_21940	COG1263	PTS System
HVW55_21945	COG0366	Alpha amylase catalytic
HVW55_21950	COG1328	CTP reductase activity
HVW55_21955	COG0602	queuosine metabolic process
HVW55_21960	COG3077	Addiction module antitoxin, RelB DinJ family
HVW55_21965	COG3783	Cytochrome b(562)
HVW55_21970	COG0312	modulator of DNA gyrase
HVW55_21980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HVW55_21990	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_21995	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_22000	COG1129	ABC transporter
HVW55_22005	COG1879	ABC-type sugar transport system periplasmic component
HVW55_22010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HVW55_22015	COG2337	Toxic component of a toxin-antitoxin (TA) module
HVW55_22020	COG2336	PFAM SpoVT AbrB
HVW55_22025	COG2105	PFAM AIG2 family protein
HVW55_22030	COG2911	Protein conserved in bacteria
HVW55_22035	COG0729	surface antigen
HVW55_22045	COG1253	flavin adenine dinucleotide binding
HVW55_22055	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HVW55_22065	COG1218	3'(2'),5'-bisphosphate nucleotidase
HVW55_22070	COG0737	Belongs to the 5'-nucleotidase family
HVW55_22075	COG1733	regulation of RNA biosynthetic process
HVW55_22080	COG0702	epimerase
HVW55_22085	COG0697	spore germination
HVW55_22105	COG1113	amino acid transport
HVW55_22110	COG0545	Peptidyl-prolyl cis-trans isomerase
HVW55_22115	COG3061	Opacity-associated protein A
HVW55_22125	COG0675	Transposase, IS605 OrfB family
HVW55_22150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HVW55_22190	COG3414	Phosphotransferase system galactitol-specific IIB component
HVW55_22195	COG3037	sugar-specific permease SgaT UlaA
HVW55_22210	COG1073	alpha beta
HVW55_22215	COG3650	response to hydrogen peroxide
HVW55_22225	COG1960	acyl-CoA dehydrogenase activity
HVW55_22230	COG0754	glutathionylspermidine amidase activity
HVW55_22235	COG5463	Belongs to the UPF0441 family
HVW55_22240	COG3766	membrane
HVW55_22250	COG1842	Phage shock protein A
HVW55_22255	COG3789	protein conserved in bacteria
HVW55_22260	COG2721	sulfolactate sulfo-lyase activity
HVW55_22265	COG2271	Major facilitator Superfamily
HVW55_22270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HVW55_22275	COG1414	Transcriptional regulator
HVW55_22280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVW55_22285	COG0557	exoribonuclease II activity
HVW55_22300	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HVW55_22305	COG0330	HflC and HflK could
HVW55_22310	COG0330	HflC and HflK could
HVW55_22315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HVW55_22335	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVW55_22340	COG0802	atpase or kinase
HVW55_22345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HVW55_22345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HVW55_22390	COG1511	domain protein
HVW55_22390	COG3264	Mechanosensitive ion channel
HVW55_22395	COG0531	amino acid
HVW55_22405	COG1053	succinate dehydrogenase
HVW55_22410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVW55_22425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVW55_22430	COG3040	lipid binding
HVW55_22435	COG2076	Multidrug Resistance protein
HVW55_22440	COG5510	response to toxic substance
HVW55_22445	COG5510	response to toxic substance
HVW55_22455	COG1509	lysine 2,3-aminomutase activity
HVW55_22480	COG0531	amino acid
HVW55_22485	COG3030	protein affecting phage T7 exclusion by the F plasmid
HVW55_22490	COG1027	Aspartate ammonia-lyase
HVW55_22495	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVW55_22510	COG1309	transcriptional regulator
HVW55_22520	COG3710	Transcriptional regulator
HVW55_22525	COG0531	amino acid
HVW55_22530	COG1982	Orn Lys Arg decarboxylase major
HVW55_22535	COG3104	oligopeptide transport
HVW55_22540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVW55_22555	COG2388	GCN5-related N-acetyl-transferase
HVW55_22560	COG3592	Divergent 4Fe-4S mono-cluster
HVW55_22565	COG3290	protein histidine kinase activity
HVW55_22570	COG4565	transcriptional regulatory protein
HVW55_22575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVW55_22580	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_22580	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVW55_22585	COG3647	Membrane
HVW55_22590	COG2211	Major facilitator Superfamily
HVW55_22595	COG1486	melibiose metabolic process
HVW55_22600	COG2169	Transcriptional regulator
HVW55_22605	COG1982	Orn Lys Arg decarboxylase major
HVW55_22610	COG2207	Transcriptional regulator
HVW55_22615	COG0531	amino acid
HVW55_22620	COG2194	sulfuric ester hydrolase activity
HVW55_22625	COG0745	RESPONSE REGULATOR receiver
HVW55_22630	COG0642	Histidine kinase
HVW55_22640	COG0477	Major facilitator Superfamily
HVW55_22650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HVW55_22655	COG2824	Alkylphosphonate utilization operon protein PhnA
HVW55_22660	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HVW55_22670	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HVW55_22675	COG3639	organic phosphonate transmembrane transporter activity
HVW55_22680	COG2188	Transcriptional regulator
HVW55_22685	COG3624	Phosphonate C-P lyase system protein PhnG
HVW55_22690	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HVW55_22695	COG3626	phosphonate metabolism
HVW55_22700	COG3627	carbon phosphorus lyase activity
HVW55_22705	COG4107	phosphonate C-P lyase system protein PhnK
HVW55_22710	COG4778	phosphonate C-P lyase system protein PhnL
HVW55_22715	COG3454	Phosphonate metabolism
HVW55_22720	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HVW55_22725	COG0456	acetyltransferase
HVW55_22730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HVW55_22750	COG1129	ABC transporter
HVW55_22755	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_22775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_22785	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HVW55_22795	COG1566	PFAM secretion protein HlyD family protein
HVW55_22800	COG1289	transmembrane transporter activity
HVW55_22815	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVW55_22820	COG1301	dicarboxylic acid transport
HVW55_22825	COG4235	cytochrome complex assembly
HVW55_22830	COG3088	subunit of a heme lyase
HVW55_22835	COG1138	Cytochrome C-type biogenesis protein
HVW55_22840	COG3301	Polysulphide reductase, NrfD
HVW55_22845	COG0437	4 iron, 4 sulfur cluster binding
HVW55_22850	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HVW55_22860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVW55_22865	COG3162	membrane
HVW55_22875	COG1357	PFAM Pentapeptide repeats (8 copies)
HVW55_22880	COG0025	NhaP-type Na H and K H
HVW55_22885	COG2252	PERMEase
HVW55_22890	COG0789	Transcriptional regulator
HVW55_22895	COG2207	Transcriptional regulator
HVW55_22900	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HVW55_22910	COG3385	transposase activity
HVW55_22915	COG0629	single-stranded DNA binding
HVW55_22920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HVW55_22925	COG2315	Protein conserved in bacteria
HVW55_22930	COG0432	Pfam Uncharacterised protein family UPF0047
HVW55_22935	COG3700	Belongs to the class B bacterial acid phosphatase family
HVW55_22945	COG1448	Aminotransferase
HVW55_22955	COG3201	nicotinamide mononucleotide transporter
HVW55_22960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVW55_22965	COG0305	Participates in initiation and elongation during chromosome replication
HVW55_22970	COG0604	alcohol dehydrogenase
HVW55_22980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVW55_22990	COG0735	belongs to the Fur family
HVW55_22995	COG3237	CsbD-like
HVW55_23000	COG0534	Mate efflux family protein
HVW55_23010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HVW55_23030	COG1357	PFAM Pentapeptide repeats (8 copies)
HVW55_23045	COG3842	ATPase activity
HVW55_23050	COG2182	Extracellular solute-binding protein
HVW55_23055	COG1175	transmembrane transport
HVW55_23060	COG3833	ABC-type maltose transport systems, permease component
HVW55_23065	COG0477	Major facilitator Superfamily
HVW55_23065	COG2814	Major facilitator Superfamily
HVW55_23085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVW55_23110	COG0527	aspartate kinase activity
HVW55_23120	COG3541	Predicted nucleotidyltransferase
HVW55_23135	COG1187	pseudouridine synthase activity
HVW55_23180	COG1283	sodium-dependent phosphate transmembrane transporter activity
HVW55_23185	COG1410	methionine synthase
HVW55_23185	COG0646	methionine synthase
HVW55_23190	COG1414	Transcriptional regulator
HVW55_23205	COG2224	Isocitrate lyase
HVW55_23210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HVW55_23220	COG0456	acetyltransferase
HVW55_23250	COG0151	Belongs to the GarS family
HVW55_23255	COG2204	response regulator
HVW55_23260	COG4191	Histidine kinase
HVW55_23265	COG3678	ATP-independent chaperone mediated protein folding
HVW55_23280	COG3068	Protein conserved in bacteria
HVW55_23315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVW55_23320	COG2104	thiamine diphosphate biosynthetic process
HVW55_23330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HVW55_23375	COG0250	Participates in transcription elongation, termination and antitermination
HVW55_23380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVW55_23415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HVW55_23415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HVW55_23420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HVW55_23450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HVW55_23460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HVW55_23470	COG1309	transcriptional regulator
HVW55_23475	COG0477	Major facilitator Superfamily
HVW55_23480	COG1473	amidohydrolase
HVW55_23490	COG0583	DNA-binding transcription factor activity
HVW55_23505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HVW55_23520	COG2194	sulfuric ester hydrolase activity
HVW55_23525	COG2207	Transcriptional regulator
HVW55_23530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_23535	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVW55_23540	COG1882	Formate acetyltransferase
HVW55_23545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_23550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_23555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVW55_23555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_23555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_23560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVW55_23565	COG0371	Dehydrogenase
HVW55_23570	COG3738	Protein conserved in bacteria
HVW55_23575	COG0697	spore germination
HVW55_23585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HVW55_23595	COG0460	homoserine dehydrogenase
HVW55_23595	COG0527	aspartate kinase activity
HVW55_23600	COG0626	cystathionine gamma-synthase activity
HVW55_23610	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HVW55_23620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HVW55_23625	COG1609	Transcriptional regulator
HVW55_23630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVW55_23645	COG1575	Belongs to the MenA family. Type 1 subfamily
HVW55_23670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HVW55_23680	COG1494	fructose-1,6-bisphosphatase
HVW55_23690	COG0589	response to stress
HVW55_23695	COG3691	Protein conserved in bacteria
HVW55_23700	COG3152	Membrane
HVW55_23720	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HVW55_23735	COG3678	ATP-independent chaperone mediated protein folding
HVW55_23740	COG0745	RESPONSE REGULATOR receiver
HVW55_23745	COG2205	protein histidine kinase activity
HVW55_23750	COG2258	MOSC domain
HVW55_23760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVW55_23770	COG1917	Cupin 2, conserved barrel domain protein
HVW55_23770	COG4977	sequence-specific DNA binding
HVW55_23805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_23810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_23810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVW55_23815	COG1363	Peptidase, m42
HVW55_23820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVW55_23820	COG3711	transcriptional antiterminator
HVW55_23840	COG0437	4 iron, 4 sulfur cluster binding
HVW55_23845	COG2864	formate dehydrogenase
HVW55_23855	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVW55_23860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVW55_23870	COG0456	acetyltransferase
HVW55_23885	COG1011	Hydrolase
HVW55_23895	COG2271	Major facilitator Superfamily
HVW55_23900	COG1082	Xylose isomerase domain protein TIM barrel
HVW55_23905	COG2188	Transcriptional regulator
HVW55_23915	COG0174	glutamine synthetase
HVW55_23920	COG3852	Histidine kinase
HVW55_23925	COG2204	response regulator
HVW55_23935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVW55_23940	COG3078	GTPase activator activity
HVW55_23950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVW55_23950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVW55_23955	COG0204	Acyl-transferase
HVW55_23960	COG5339	Protein conserved in bacteria
HVW55_23965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVW55_23970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HVW55_23975	COG3084	Protein conserved in bacteria
HVW55_23980	COG0746	molybdenum cofactor guanylyltransferase activity
HVW55_23985	COG1763	Mo-molybdopterin cofactor biosynthetic process
HVW55_24010	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HVW55_24015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVW55_24020	COG1739	Uncharacterized protein family UPF0029
HVW55_24040	COG0543	2 iron, 2 sulfur cluster binding
HVW55_24045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HVW55_24050	COG0250	Participates in transcription elongation, termination and antitermination
HVW55_24055	COG0084	hydrolase, TatD family'
HVW55_24060	COG0805	protein transport
HVW55_24065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVW55_24070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVW55_24080	COG3165	ubiquinone biosynthetic process from chorismate
HVW55_24090	COG1322	Protein conserved in bacteria
HVW55_24095	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HVW55_24100	COG0412	Dienelactone hydrolase
HVW55_24110	COG0583	DNA-binding transcription factor activity
HVW55_24115	COG0697	spore germination
HVW55_24120	COG0561	phosphatase activity
HVW55_24125	COG2267	carboxylic ester hydrolase activity
HVW55_24130	COG1280	lysine exporter protein (LysE YggA)
HVW55_24135	COG1280	lysine exporter protein (LysE YggA)
HVW55_24140	COG0514	ATP-dependent DNA helicase (RecQ)
HVW55_24145	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HVW55_24150	COG2050	protein possibly involved in aromatic compounds catabolism
HVW55_24155	COG2962	Rard protein
HVW55_24180	COG0598	Magnesium transport protein CorA
HVW55_24185	COG3698	Phosphodiester glycosidase
HVW55_24190	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HVW55_24195	COG0210	DNA helicase
HVW55_24210	COG3159	Protein conserved in bacteria
HVW55_24220	COG5567	small periplasmic lipoprotein
HVW55_24235	COG3072	Adenylate cyclase
HVW55_24245	COG1587	Uroporphyrinogen-III synthase
HVW55_24250	COG2959	enzyme of heme biosynthesis
HVW55_24255	COG3071	HemY protein
HVW55_24260	COG3119	arylsulfatase activity
HVW55_24265	COG0641	radical SAM
HVW55_24290	COG1113	amino acid transport
HVW55_24310	COG2244	polysaccharide biosynthetic process
HVW55_24315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HVW55_24320	COG0456	acetyltransferase
HVW55_24325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HVW55_24330	COG1088	dTDP-glucose 4,6-dehydratase activity
HVW55_24335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HVW55_24340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HVW55_24345	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVW55_24350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HVW55_24355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HVW55_24365	COG3118	belongs to the thioredoxin family
HVW55_24380	COG0210	DNA helicase
HVW55_24385	COG3692	DNA binding
HVW55_24390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVW55_24400	COG0583	DNA-binding transcription factor activity
HVW55_24405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVW55_24415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVW55_24420	COG3978	acetolactate synthase activity
HVW55_24440	COG0606	chelatase, subunit chli
HVW55_24445	COG3085	chromosome segregation
HVW55_24485	COG2186	Transcriptional regulator
HVW55_24490	COG0477	Major facilitator Superfamily
HVW55_24495	COG1609	Transcriptional regulator
HVW55_24500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVW55_24505	COG1879	ABC-type sugar transport system periplasmic component
HVW55_24510	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVW55_24515	COG1129	ABC transporter
HVW55_24545	COG1522	sequence-specific DNA binding
HVW55_24550	COG0716	FMN binding
HVW55_24565	COG3312	ion transport
HVW55_24615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HVW55_24620	COG3539	Fimbrial protein
HVW55_24625	COG3121	Chaperone
HVW55_24640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HVW55_24645	COG0573	inorganic phosphate transmembrane transporter activity
HVW55_24650	COG0581	inorganic phosphate transmembrane transporter activity
HVW55_24655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HVW55_24660	COG0704	Plays a role in the regulation of phosphate uptake
HVW55_24665	COG3711	transcriptional antiterminator
HVW55_24670	COG2190	(PTS) system
HVW55_24670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVW55_24670	COG1263	PTS System
HVW55_24675	COG2723	6-phospho-beta-galactosidase activity
HVW55_24685	COG2382	esterase
HVW55_24690	COG0363	glucosamine-6-phosphate deaminase activity
HVW55_24710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVW55_24715	COG2252	PERMEase
HVW55_24720	COG0431	NADPH-dependent FMN reductase
HVW55_24725	COG2091	lysine biosynthetic process via aminoadipic acid
HVW55_24740	COG0814	amino acid
HVW55_24935	COG0281	malic enzyme
HVW55_25345	COG4372	Transposase
HVW55_25350	COG3436	PFAM IS66 Orf2 family protein