locus-tag	class	description
HVZ24_00010	COG0592	DNA-directed DNA polymerase activity
HVZ24_00020	COG0187	DNA topoisomerase II activity
HVZ24_00025	COG3753	Protein conserved in bacteria
HVZ24_00030	COG0561	phosphatase activity
HVZ24_00040	COG2186	Transcriptional regulator
HVZ24_00045	COG3734	2-keto-3-deoxy-galactonokinase
HVZ24_00050	COG0800	Aldolase
HVZ24_00060	COG2271	Major facilitator Superfamily
HVZ24_00065	COG0644	oxidoreductase
HVZ24_00070	COG0823	Involved in the tonB-independent uptake of proteins
HVZ24_00075	COG5645	(Lipo)protein
HVZ24_00095	COG2188	Transcriptional regulator
HVZ24_00110	COG2207	Transcriptional regulator
HVZ24_00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVZ24_00120	COG3119	arylsulfatase activity
HVZ24_00130	COG2149	membrane
HVZ24_00140	COG0641	radical SAM
HVZ24_00145	COG2814	Major facilitator Superfamily
HVZ24_00160	COG0028	Belongs to the TPP enzyme family
HVZ24_00165	COG0440	acetolactate synthase activity
HVZ24_00170	COG2197	response regulator
HVZ24_00175	COG3851	Histidine kinase
HVZ24_00180	COG2271	Major facilitator Superfamily
HVZ24_00185	COG2271	Major facilitator Superfamily
HVZ24_00195	COG2252	PERMEase
HVZ24_00215	COG1464	Belongs to the NlpA lipoprotein family
HVZ24_00220	COG0697	spore germination
HVZ24_00225	COG2814	Major facilitator Superfamily
HVZ24_00240	COG2211	Major facilitator Superfamily
HVZ24_00245	COG1501	Belongs to the glycosyl hydrolase 31 family
HVZ24_00250	COG2982	Protein involved in outer membrane biogenesis
HVZ24_00255	COG2233	PERMEase
HVZ24_00260	COG0786	glutamate:sodium symporter activity
HVZ24_00265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HVZ24_00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVZ24_00275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVZ24_00285	COG0194	GDP metabolic process
HVZ24_00295	COG2860	membrane
HVZ24_00300	COG3645	SOS response
HVZ24_00305	COG1561	YicC-like family, N-terminal region
HVZ24_00325	COG0756	dUTP diphosphatase activity
HVZ24_00330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HVZ24_00360	COG1519	Transferase
HVZ24_00365	COG0859	PFAM glycosyl transferase family 9
HVZ24_00370	COG0438	transferase activity, transferring glycosyl groups
HVZ24_00375	COG0515	serine threonine protein kinase
HVZ24_00380	COG0438	transferase activity, transferring glycosyl groups
HVZ24_00380	COG4641	Protein conserved in bacteria
HVZ24_00385	COG0438	transferase activity, transferring glycosyl groups
HVZ24_00390	COG1442	glycosyl transferase family 8
HVZ24_00395	COG1442	glycosyl transferase family 8
HVZ24_00400	COG3642	lipopolysaccharide core region biosynthetic process
HVZ24_00410	COG0859	PFAM glycosyl transferase family 9
HVZ24_00415	COG3307	-O-antigen
HVZ24_00420	COG0859	PFAM glycosyl transferase family 9
HVZ24_00425	COG0859	PFAM glycosyl transferase family 9
HVZ24_00440	COG0156	8-amino-7-oxononanoate synthase activity
HVZ24_00450	COG1216	Glycosyl transferase, family 2
HVZ24_00455	COG2861	carbohydrate metabolic process
HVZ24_00460	COG4942	peptidase
HVZ24_00465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HVZ24_00470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVZ24_00475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVZ24_00490	COG1045	serine acetyltransferase
HVZ24_00495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HVZ24_00505	COG2186	Transcriptional regulator
HVZ24_00510	COG1620	l-lactate permease
HVZ24_00525	COG3722	fumarate hydratase activity
HVZ24_00535	COG2213	PTS system mannitol-specific
HVZ24_00535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_00545	COG1566	PFAM secretion protein HlyD family protein
HVZ24_00555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVZ24_00560	COG3209	COG3209 Rhs family protein
HVZ24_00565	COG1413	lyase activity
HVZ24_00570	COG3209	COG3209 Rhs family protein
HVZ24_00575	COG0625	glutathione transferase activity
HVZ24_00585	COG3276	selenocysteine insertion sequence binding
HVZ24_00590	COG1454	alcohol dehydrogenase
HVZ24_00595	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_00610	COG1566	PFAM secretion protein HlyD family protein
HVZ24_00615	COG0583	DNA-binding transcription factor activity
HVZ24_00620	COG3713	MltA-interacting MipA family protein
HVZ24_00630	COG0235	Class ii aldolase
HVZ24_00635	COG3623	hexulose-6-phosphate isomerase
HVZ24_00640	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HVZ24_00645	COG1070	Carbohydrate kinase
HVZ24_00650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVZ24_00655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HVZ24_00660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVZ24_00665	COG2731	YhcH YjgK YiaL family protein
HVZ24_00675	COG1414	Transcriptional regulator
HVZ24_00680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_00685	COG3977	Valine--pyruvate aminotransferase
HVZ24_00690	COG0366	Alpha amylase catalytic
HVZ24_00695	COG2992	FlgJ-related protein
HVZ24_00700	COG2207	Transcriptional regulator
HVZ24_00700	COG1609	Transcriptional regulator
HVZ24_00705	COG4214	carbohydrate transport
HVZ24_00710	COG1129	ABC transporter
HVZ24_00715	COG4213	ABC transporter substrate-binding protein
HVZ24_00725	COG1070	Carbohydrate kinase
HVZ24_00735	COG4682	membrane
HVZ24_00740	COG3274	enterobacterial common antigen metabolic process
HVZ24_00770	COG1278	Cold shock
HVZ24_00775	COG2944	sequence-specific DNA binding
HVZ24_00790	COG2885	chlorophyll binding
HVZ24_00795	COG0243	molybdopterin cofactor binding
HVZ24_00800	COG0456	acetyltransferase
HVZ24_00805	COG2818	Glycosylase
HVZ24_00810	COG5571	outer membrane autotransporter
HVZ24_00815	COG2223	nitrite transmembrane transporter activity
HVZ24_00820	COG2194	sulfuric ester hydrolase activity
HVZ24_00830	COG0747	negative chemotaxis
HVZ24_00835	COG0601	transmembrane transport
HVZ24_00840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVZ24_00845	COG0444	Belongs to the ABC transporter superfamily
HVZ24_00850	COG4608	Belongs to the ABC transporter superfamily
HVZ24_00855	COG0814	amino acid
HVZ24_00865	COG2194	sulfuric ester hydrolase activity
HVZ24_00895	COG1215	transferase activity, transferring glycosyl groups
HVZ24_00900	COG1215	transferase activity, transferring glycosyl groups
HVZ24_00905	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HVZ24_00910	COG3118	belongs to the thioredoxin family
HVZ24_00910	COG0457	Tetratricopeptide repeat
HVZ24_00915	COG2199	diguanylate cyclase activity
HVZ24_00915	COG2200	EAL domain
HVZ24_00925	COG0612	Peptidase, M16
HVZ24_00930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_00935	COG2200	EAL domain
HVZ24_00940	COG2982	Protein involved in outer membrane biogenesis
HVZ24_00945	COG0477	Major facilitator Superfamily
HVZ24_00950	COG1295	ribonuclease BN
HVZ24_00955	COG0583	DNA-binding transcription factor activity
HVZ24_00960	COG2197	response regulator
HVZ24_00970	COG1858	cytochrome C peroxidase
HVZ24_00975	COG0076	glutamate decarboxylase activity
HVZ24_00980	COG2207	Transcriptional regulator
HVZ24_00985	COG2207	Transcriptional regulator
HVZ24_00990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVZ24_00995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_01005	COG2771	luxR family
HVZ24_01010	COG3247	response to pH
HVZ24_01025	COG1285	pathogenesis
HVZ24_01030	COG2197	response regulator
HVZ24_01035	COG3065	identical protein binding
HVZ24_01045	COG1393	Belongs to the ArsC family
HVZ24_01050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HVZ24_01055	COG0640	Transcriptional regulator
HVZ24_01065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVZ24_01070	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HVZ24_01075	COG0339	signal peptide processing
HVZ24_01085	COG3104	oligopeptide transport
HVZ24_01090	COG0589	response to stress
HVZ24_01100	COG0306	phosphate transporter
HVZ24_01105	COG2081	HI0933 family
HVZ24_01125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_01130	COG1129	ABC transporter
HVZ24_01130	COG0842	Transport permease protein
HVZ24_01135	COG0842	Transport permease protein
HVZ24_01140	COG5433	transposase activity
HVZ24_01145	COG1413	lyase activity
HVZ24_01155	COG3209	COG3209 Rhs family protein
HVZ24_01165	COG1124	(ABC) transporter
HVZ24_01170	COG0444	Belongs to the ABC transporter superfamily
HVZ24_01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVZ24_01180	COG0601	transmembrane transport
HVZ24_01185	COG0747	negative chemotaxis
HVZ24_01190	COG2091	lysine biosynthetic process via aminoadipic acid
HVZ24_01195	COG0628	permease
HVZ24_01200	COG0477	Major facilitator Superfamily
HVZ24_01210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HVZ24_01220	COG2217	Heavy metal translocating P-type atpase
HVZ24_01225	COG3714	YhhN family
HVZ24_01235	COG3776	membrane
HVZ24_01240	COG0742	ribosomal rna small subunit methyltransferase
HVZ24_01245	COG0552	protein localization to endoplasmic reticulum
HVZ24_01250	COG2884	Cell division ATP-binding protein ftsE
HVZ24_01255	COG2177	Part of the ABC transporter FtsEX involved in
HVZ24_01260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVZ24_01265	COG0683	leucine binding
HVZ24_01270	COG0456	acetyltransferase
HVZ24_01275	COG0683	leucine binding
HVZ24_01280	COG0559	Belongs to the binding-protein-dependent transport system permease family
HVZ24_01285	COG4177	L-phenylalanine transmembrane transporter activity
HVZ24_01290	COG0411	ABC transporter
HVZ24_01295	COG0410	ABC transporter
HVZ24_01300	COG1653	transport
HVZ24_01305	COG1175	transmembrane transport
HVZ24_01310	COG0395	ABC-type sugar transport system, permease component
HVZ24_01315	COG3842	ATPase activity
HVZ24_01320	COG0584	glycerophosphoryl diester phosphodiesterase
HVZ24_01330	COG0405	Gamma-glutamyltransferase
HVZ24_01350	COG3157	Type VI secretion system effector, Hcp
HVZ24_01355	COG1247	-acetyltransferase
HVZ24_01360	COG0673	inositol 2-dehydrogenase activity
HVZ24_01365	COG1741	Belongs to the pirin family
HVZ24_01370	COG1609	Transcriptional regulator
HVZ24_01375	COG3265	gluconokinase activity
HVZ24_01380	COG2610	gluconate transmembrane transporter activity
HVZ24_01385	COG2095	MarC family integral membrane protein
HVZ24_01390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVZ24_01415	COG0058	SHG alpha-glucan phosphorylase activity
HVZ24_01425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVZ24_01440	COG1349	DNA-binding transcription factor activity
HVZ24_01445	COG4650	regulator
HVZ24_01450	COG1690	Belongs to the RtcB family
HVZ24_01465	COG0058	SHG alpha-glucan phosphorylase activity
HVZ24_01470	COG1640	4-alpha-glucanotransferase
HVZ24_01475	COG2610	gluconate transmembrane transporter activity
HVZ24_01485	COG1040	competence protein
HVZ24_01495	COG5464	transposase or invertase
HVZ24_01505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HVZ24_01510	COG1918	ferrous iron import across plasma membrane
HVZ24_01515	COG2183	response to ionizing radiation
HVZ24_01520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVZ24_01525	COG0745	RESPONSE REGULATOR receiver
HVZ24_01530	COG2205	protein histidine kinase activity
HVZ24_01540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HVZ24_01550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HVZ24_01555	COG1011	Hydrolase
HVZ24_01565	COG0494	nUDIX hydrolase
HVZ24_01570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HVZ24_01575	COG4972	Pilus assembly protein
HVZ24_01580	COG3166	PFAM Fimbrial assembly family protein
HVZ24_01595	COG4796	Type ii and iii secretion system protein
HVZ24_01610	COG3266	domain, Protein
HVZ24_01615	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HVZ24_01620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HVZ24_01625	COG0546	phosphoglycolate phosphatase activity
HVZ24_01630	COG0180	Tryptophanyl-tRNA synthetase
HVZ24_01635	COG2188	Transcriptional regulator
HVZ24_01645	COG3457	Alanine racemase
HVZ24_01650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HVZ24_01655	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HVZ24_01670	COG0626	cystathionine gamma-synthase activity
HVZ24_01675	COG2188	Transcriptional regulator
HVZ24_01680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_01685	COG1082	Xylose isomerase domain protein TIM barrel
HVZ24_01690	COG2222	sugar isomerase
HVZ24_01695	COG0531	amino acid
HVZ24_01710	COG2116	formate transmembrane transporter activity
HVZ24_01715	COG2146	nitrite reductase [NAD(P)H] activity
HVZ24_01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HVZ24_01730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HVZ24_01740	COG2184	nucleotidyltransferase activity
HVZ24_01745	COG0512	Glutamine amidotransferase of anthranilate synthase
HVZ24_01750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HVZ24_01755	COG1289	transmembrane transporter activity
HVZ24_01760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVZ24_01765	COG1765	OsmC-like protein
HVZ24_01770	COG3954	Phosphoribulokinase
HVZ24_01780	COG0429	hydrolase of the alpha beta-hydrolase fold
HVZ24_01785	COG0488	(ABC) transporter
HVZ24_01800	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HVZ24_01805	COG1047	Peptidyl-prolyl cis-trans
HVZ24_01815	COG0545	Peptidyl-prolyl cis-trans isomerase
HVZ24_01820	COG2964	Protein conserved in bacteria
HVZ24_01860	COG3979	chitinase
HVZ24_01865	COG2906	2 iron, 2 sulfur cluster binding
HVZ24_01870	COG2193	ferroxidase activity
HVZ24_01875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HVZ24_01880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HVZ24_01885	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HVZ24_01890	COG3156	type II secretion system protein K
HVZ24_01895	COG4795	General secretion pathway protein
HVZ24_01900	COG2165	general secretion pathway protein
HVZ24_01905	COG2165	general secretion pathway protein
HVZ24_01910	COG2165	general secretion pathway protein
HVZ24_01915	COG1459	type II secretion system
HVZ24_01920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVZ24_01925	COG1450	Type ii and iii secretion system protein
HVZ24_01930	COG3031	protein transport across the cell outer membrane
HVZ24_01935	COG3409	Peptidoglycan-binding domain 1 protein
HVZ24_01935	COG3267	Type II secretory pathway component ExeA
HVZ24_01960	COG0089	rRNA binding
HVZ24_02050	COG0201	protein transport
HVZ24_02090	COG0789	Transcriptional regulator
HVZ24_02095	COG3036	rescue of stalled ribosome
HVZ24_02105	COG0569	domain protein
HVZ24_02125	COG0758	DNA mediated transformation
HVZ24_02135	COG0551	DNA topoisomerase type I activity
HVZ24_02155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVZ24_02195	COG1126	abc transporter atp-binding protein
HVZ24_02200	COG0765	amino acid transport
HVZ24_02205	COG4597	amino acid ABC transporter
HVZ24_02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_02220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVZ24_02225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_02230	COG1309	transcriptional regulator
HVZ24_02240	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HVZ24_02250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVZ24_02260	COG4145	pantothenate transmembrane transporter activity
HVZ24_02265	COG3924	membrane
HVZ24_02270	COG0439	Biotin carboxylase
HVZ24_02275	COG0511	ligase activity, forming carbon-carbon bonds
HVZ24_02280	COG0604	alcohol dehydrogenase
HVZ24_02285	COG2200	EAL domain
HVZ24_02285	COG2199	diguanylate cyclase activity
HVZ24_02290	COG1077	Cell shape determining protein MreB Mrl
HVZ24_02295	COG1792	Involved in formation and maintenance of cell shape
HVZ24_02300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HVZ24_02305	COG0424	maF-like protein
HVZ24_02310	COG1530	ribonuclease E activity
HVZ24_02315	COG3164	Protein of unknown function
HVZ24_02320	COG0312	modulator of DNA gyrase
HVZ24_02325	COG0583	DNA-binding transcription factor activity
HVZ24_02345	COG2732	(Barnase) inhibitor
HVZ24_02365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVZ24_02370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVZ24_02375	COG3105	Protein conserved in bacteria
HVZ24_02380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HVZ24_02395	COG0625	glutathione transferase activity
HVZ24_02400	COG2969	positive regulation of protein catabolic process
HVZ24_02405	COG3069	C4-dicarboxylate transmembrane transporter activity
HVZ24_02435	COG2731	YhcH YjgK YiaL family protein
HVZ24_02440	COG4804	nuclease activity
HVZ24_02465	COG3188	usher protein
HVZ24_02470	COG3121	Chaperone
HVZ24_02475	COG3539	Fimbrial protein
HVZ24_02480	COG0493	'glutamate synthase
HVZ24_02485	COG0069	glutamate synthase activity
HVZ24_02485	COG0067	glutamate synthase
HVZ24_02485	COG0070	glutamate synthase
HVZ24_02490	COG1242	4 iron, 4 sulfur cluster binding
HVZ24_02495	COG2198	Histidine kinase
HVZ24_02495	COG5002	protein histidine kinase activity
HVZ24_02495	COG0784	Response regulator, receiver
HVZ24_02500	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HVZ24_02510	COG0515	serine threonine protein kinase
HVZ24_02515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_02530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVZ24_02535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HVZ24_02540	COG1137	ATPase activity
HVZ24_02545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HVZ24_02550	COG3117	lipopolysaccharide transmembrane transporter activity
HVZ24_02555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HVZ24_02560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVZ24_02560	COG0517	IMP dehydrogenase activity
HVZ24_02565	COG0530	calcium, potassium:sodium antiporter activity
HVZ24_02570	COG1127	ABC transporter
HVZ24_02575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HVZ24_02580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVZ24_02585	COG2854	intermembrane phospholipid transfer
HVZ24_02590	COG3113	response to antibiotic
HVZ24_02595	COG5007	Belongs to the BolA IbaG family
HVZ24_02605	COG3423	Transcriptional regulator
HVZ24_02610	COG0142	geranyltranstransferase activity
HVZ24_02625	COG0697	spore germination
HVZ24_02635	COG2027	D-alanyl-D-alanine carboxypeptidase
HVZ24_02640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVZ24_02645	COG1534	Rna-binding protein
HVZ24_02655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HVZ24_02660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HVZ24_02670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVZ24_02680	COG2194	sulfuric ester hydrolase activity
HVZ24_02700	COG0195	Participates in both transcription termination and antitermination
HVZ24_02740	COG0513	Belongs to the DEAD box helicase family
HVZ24_02745	COG0814	amino acid
HVZ24_02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HVZ24_02755	COG0826	peptidase U32
HVZ24_02760	COG0826	peptidase U32
HVZ24_02765	COG3154	lipid carrier protein
HVZ24_02770	COG3153	acetyltransferase
HVZ24_02785	COG0693	protein deglycase activity
HVZ24_02790	COG0702	epimerase
HVZ24_02795	COG0701	Predicted permease
HVZ24_02800	COG2823	Periplasmic or secreted lipoprotein
HVZ24_02815	COG3107	peptidoglycan biosynthetic process
HVZ24_02820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HVZ24_02825	COG3539	Fimbrial protein
HVZ24_02830	COG3188	usher protein
HVZ24_02835	COG3121	Chaperone
HVZ24_02840	COG3539	Fimbrial protein
HVZ24_02845	COG0363	glucosamine-6-phosphate deaminase activity
HVZ24_02850	COG3716	PTS system mannose fructose sorbose family IID component
HVZ24_02855	COG3715	PTS system
HVZ24_02870	COG2222	sugar isomerase
HVZ24_02875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVZ24_02880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_02885	COG3716	PTS system mannose fructose sorbose family IID component
HVZ24_02895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_02905	COG1349	DNA-binding transcription factor activity
HVZ24_02915	COG2002	toxin-antitoxin pair type II binding
HVZ24_02920	COG2721	sulfolactate sulfo-lyase activity
HVZ24_02925	COG2271	Major facilitator Superfamily
HVZ24_02935	COG2084	Dehydrogenase
HVZ24_02940	COG1929	Belongs to the glycerate kinase type-1 family
HVZ24_02965	COG0583	DNA-binding transcription factor activity
HVZ24_02970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVZ24_02980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HVZ24_02985	COG1882	Formate acetyltransferase
HVZ24_02990	COG0251	oxidation-reduction process
HVZ24_02995	COG1760	l-serine dehydratase
HVZ24_03000	COG0814	amino acid
HVZ24_03015	COG1741	Belongs to the pirin family
HVZ24_03020	COG0583	DNA-binding transcription factor activity
HVZ24_03025	COG3152	Membrane
HVZ24_03030	COG3152	Membrane
HVZ24_03035	COG0435	Glutathione S-transferase
HVZ24_03040	COG2259	Doxx family
HVZ24_03050	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HVZ24_03055	COG4575	ribosome binding
HVZ24_03060	COG1422	Protein of unknown function (DUF1090)
HVZ24_03070	COG0586	Pfam SNARE associated Golgi protein
HVZ24_03075	COG2186	Transcriptional regulator
HVZ24_03080	COG2271	Major facilitator Superfamily
HVZ24_03090	COG2721	sulfolactate sulfo-lyase activity
HVZ24_03100	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HVZ24_03105	COG0861	Integral membrane protein TerC family
HVZ24_03110	COG0673	inositol 2-dehydrogenase activity
HVZ24_03115	COG2949	membrane
HVZ24_03120	COG1451	nucleotide metabolic process
HVZ24_03130	COG4680	protein conserved in bacteria
HVZ24_03135	COG5499	transcription regulator containing HTH domain
HVZ24_03140	COG1902	pentaerythritol trinitrate reductase activity
HVZ24_03140	COG0446	pyridine nucleotide-disulphide oxidoreductase
HVZ24_03145	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HVZ24_03145	COG3408	Glycogen debranching enzyme
HVZ24_03155	COG0531	amino acid
HVZ24_03160	COG2731	YhcH YjgK YiaL family protein
HVZ24_03165	COG3250	beta-galactosidase activity
HVZ24_03170	COG1609	Transcriptional regulator
HVZ24_03175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HVZ24_03185	COG0840	transmembrane signaling receptor activity
HVZ24_03190	COG1695	Transcriptional regulator
HVZ24_03195	COG2375	cellular response to nickel ion
HVZ24_03210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVZ24_03215	COG0358	DNA primase activity
HVZ24_03220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HVZ24_03230	COG0471	metal ion transport
HVZ24_03235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_03240	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_03245	COG0583	DNA-binding transcription factor activity
HVZ24_03255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVZ24_03270	COG4991	sh3 domain protein
HVZ24_03275	COG3025	triphosphatase activity
HVZ24_03300	COG2268	Band 7 protein
HVZ24_03305	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVZ24_03315	COG3539	Fimbrial protein
HVZ24_03320	COG3121	Chaperone
HVZ24_03325	COG3188	usher protein
HVZ24_03330	COG3539	Fimbrial protein
HVZ24_03335	COG2960	long-chain fatty acid transporting porin activity
HVZ24_03355	COG3384	dioxygenase
HVZ24_03360	COG0754	glutathionylspermidine amidase activity
HVZ24_03370	COG1538	Outer membrane efflux protein
HVZ24_03375	COG0494	nUDIX hydrolase
HVZ24_03380	COG3151	Protein conserved in bacteria
HVZ24_03385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HVZ24_03390	COG3150	esterase
HVZ24_03395	COG0187	DNA topoisomerase II activity
HVZ24_03400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HVZ24_03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
HVZ24_03415	COG0642	Histidine kinase
HVZ24_03420	COG0745	RESPONSE REGULATOR receiver
HVZ24_03425	COG3111	PFAM Bacterial OB fold (BOF) protein
HVZ24_03430	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HVZ24_03440	COG2944	sequence-specific DNA binding
HVZ24_03445	COG4166	transmembrane transport
HVZ24_03450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVZ24_03455	COG0204	Acyl-transferase
HVZ24_03460	COG2132	Multicopper oxidase
HVZ24_03465	COG1032	radical SAM domain protein
HVZ24_03470	COG4238	major outer membrane lipoprotein
HVZ24_03480	COG0656	L-ascorbic acid biosynthetic process
HVZ24_03485	COG1979	alcohol dehydrogenase
HVZ24_03490	COG2207	Transcriptional regulator
HVZ24_03495	COG0586	Pfam SNARE associated Golgi protein
HVZ24_03500	COG0626	cystathionine gamma-synthase activity
HVZ24_03505	COG0811	peptide transport
HVZ24_03510	COG0848	biopolymer transport protein
HVZ24_03515	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_03525	COG0667	Aldo Keto reductase
HVZ24_03540	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVZ24_03545	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_03550	COG5557	Pfam Polysulphide reductase, NrfD
HVZ24_03555	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVZ24_03560	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVZ24_03565	COG1773	rubredoxin
HVZ24_03575	COG0298	carbon dioxide binding
HVZ24_03580	COG0625	glutathione transferase activity
HVZ24_03585	COG0754	glutathionylspermidine amidase activity
HVZ24_03590	COG0306	phosphate transporter
HVZ24_03595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HVZ24_03605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HVZ24_03610	COG2244	polysaccharide biosynthetic process
HVZ24_03620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HVZ24_03625	COG0795	lipopolysaccharide-transporting ATPase activity
HVZ24_03635	COG0156	8-amino-7-oxononanoate synthase activity
HVZ24_03640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HVZ24_03650	COG0318	PFAM AMP-dependent synthetase and ligase
HVZ24_03655	COG0456	acetyltransferase
HVZ24_03660	COG2186	Transcriptional regulator
HVZ24_03665	COG0277	FAD linked oxidase domain protein
HVZ24_03670	COG0277	FAD linked oxidase domain protein
HVZ24_03675	COG0247	lactate metabolic process
HVZ24_03680	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HVZ24_03685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HVZ24_03690	COG1620	l-lactate permease
HVZ24_03695	COG3064	Membrane
HVZ24_03705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HVZ24_03730	COG1472	Belongs to the glycosyl hydrolase 3 family
HVZ24_03735	COG5297	Belongs to the glycosyl hydrolase family 6
HVZ24_03735	COG2273	Hydrolase Family 16
HVZ24_03740	COG1609	Transcriptional regulator
HVZ24_03755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVZ24_03760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVZ24_03765	COG2723	6-phospho-beta-galactosidase activity
HVZ24_03770	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVZ24_03780	COG0582	viral genome integration into host DNA
HVZ24_03790	COG1811	Na channel or pump
HVZ24_03795	COG1982	Orn Lys Arg decarboxylase major
HVZ24_03800	COG2211	Major facilitator Superfamily
HVZ24_03815	COG1194	a g-specific adenine glycosylase
HVZ24_03825	COG3171	Protein conserved in bacteria
HVZ24_03835	COG0252	asparaginase activity
HVZ24_03845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVZ24_03850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HVZ24_03860	COG0762	integral membrane protein
HVZ24_03865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HVZ24_03870	COG2805	Type II/IV secretion system protein
HVZ24_03885	COG0189	ligase activity
HVZ24_03890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HVZ24_03895	COG2356	endonuclease I
HVZ24_03905	COG2814	Major facilitator Superfamily
HVZ24_03925	COG1166	arginine decarboxylase activity
HVZ24_03935	COG0501	Belongs to the peptidase M48B family
HVZ24_03940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVZ24_03945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_03950	COG2213	PTS system mannitol-specific
HVZ24_03955	COG1063	alcohol dehydrogenase
HVZ24_03960	COG1494	fructose-1,6-bisphosphatase
HVZ24_03965	COG3722	fumarate hydratase activity
HVZ24_03970	COG1072	(Pantothenic acid kinase))
HVZ24_03985	COG0191	fructose-bisphosphate aldolase activity
HVZ24_03990	COG0668	transmembrane transport
HVZ24_03995	COG1279	arginine transmembrane transporter activity
HVZ24_04000	COG2968	Membrane
HVZ24_04005	COG0583	DNA-binding transcription factor activity
HVZ24_04010	COG0427	acetyl-CoA hydrolase
HVZ24_04015	COG1024	Enoyl-CoA hydratase
HVZ24_04020	COG1703	isobutyryl-CoA mutase activity
HVZ24_04025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVZ24_04025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVZ24_04045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HVZ24_04055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HVZ24_04075	COG0006	proline dipeptidase activity
HVZ24_04080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVZ24_04085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVZ24_04110	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_04115	COG2723	6-phospho-beta-galactosidase activity
HVZ24_04125	COG1272	protein, Hemolysin III
HVZ24_04135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HVZ24_04145	COG0716	FMN binding
HVZ24_04150	COG4974	Belongs to the 'phage' integrase family
HVZ24_04155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVZ24_04160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HVZ24_04170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVZ24_04190	COG2233	PERMEase
HVZ24_04200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_04205	COG2252	PERMEase
HVZ24_04210	COG0402	S-adenosylhomocysteine deaminase activity
HVZ24_04215	COG2233	PERMEase
HVZ24_04220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVZ24_04220	COG2080	2 iron, 2 sulfur cluster binding
HVZ24_04225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVZ24_04230	COG0402	S-adenosylhomocysteine deaminase activity
HVZ24_04235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_04235	COG0493	'glutamate synthase
HVZ24_04240	COG2068	MobA-Related Protein
HVZ24_04245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HVZ24_04250	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HVZ24_04250	COG3608	succinylglutamate desuccinylase aspartoacylase
HVZ24_04255	COG0549	Belongs to the carbamate kinase family
HVZ24_04265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HVZ24_04270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVZ24_04275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HVZ24_04285	COG2080	2 iron, 2 sulfur cluster binding
HVZ24_04290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVZ24_04295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVZ24_04300	COG4942	peptidase
HVZ24_04400	COG3710	Transcriptional regulator
HVZ24_04400	COG0457	Tetratricopeptide repeat
HVZ24_04405	COG0457	Tetratricopeptide repeat
HVZ24_04430	COG3710	Transcriptional regulator
HVZ24_04435	COG2771	luxR family
HVZ24_04440	COG0814	amino acid
HVZ24_04445	COG0183	Belongs to the thiolase family
HVZ24_04455	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_04460	COG2814	Major facilitator Superfamily
HVZ24_04465	COG1794	racemase activity, acting on amino acids and derivatives
HVZ24_04470	COG0583	DNA-binding transcription factor activity
HVZ24_04480	COG1609	Transcriptional regulator
HVZ24_04495	COG0667	Aldo Keto reductase
HVZ24_04505	COG0861	Integral membrane protein TerC family
HVZ24_04520	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HVZ24_04535	COG2165	general secretion pathway protein
HVZ24_04540	COG4795	General secretion pathway protein
HVZ24_04550	COG4967	type IV pilus modification protein PilV
HVZ24_04555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HVZ24_04560	COG1025	Belongs to the peptidase M16 family
HVZ24_04565	COG1074	ATP-dependent DNA helicase activity
HVZ24_04570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HVZ24_04575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HVZ24_04575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HVZ24_04580	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVZ24_04600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HVZ24_04605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HVZ24_04610	COG2166	iron-sulfur cluster assembly
HVZ24_04615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HVZ24_04625	COG0583	DNA-binding transcription factor activity
HVZ24_04630	COG2363	Small membrane protein
HVZ24_04640	COG1349	DNA-binding transcription factor activity
HVZ24_04650	COG1070	Carbohydrate kinase
HVZ24_04660	COG0738	Major facilitator superfamily
HVZ24_04665	COG0235	Class ii aldolase
HVZ24_04670	COG1454	alcohol dehydrogenase
HVZ24_04680	COG1760	l-serine dehydratase
HVZ24_04685	COG0814	amino acid
HVZ24_04690	COG1611	Belongs to the LOG family
HVZ24_04705	COG3098	single-species biofilm formation
HVZ24_04710	COG0564	pseudouridine synthase activity
HVZ24_04715	COG0716	FMN binding
HVZ24_04720	COG2271	Major facilitator Superfamily
HVZ24_04725	COG4948	Mandelate Racemase Muconate Lactonizing
HVZ24_04730	COG4948	Mandelate Racemase Muconate Lactonizing
HVZ24_04735	COG2205	protein histidine kinase activity
HVZ24_04735	COG3437	response regulator, receiver
HVZ24_04735	COG3850	Histidine kinase
HVZ24_04735	COG4999	Histidine kinase
HVZ24_04740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HVZ24_04745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVZ24_04750	COG2336	PFAM SpoVT AbrB
HVZ24_04755	COG2337	Toxic component of a toxin-antitoxin (TA) module
HVZ24_04760	COG3956	TIGRFAM MazG family protein
HVZ24_04775	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HVZ24_04785	COG0602	queuosine metabolic process
HVZ24_04790	COG1070	Carbohydrate kinase
HVZ24_04795	COG2223	nitrite transmembrane transporter activity
HVZ24_04805	COG0277	FAD linked oxidase domain protein
HVZ24_04810	COG0477	Major facilitator Superfamily
HVZ24_04815	COG2086	electron transfer activity
HVZ24_04820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HVZ24_04825	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HVZ24_04830	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVZ24_04835	COG0644	oxidoreductase
HVZ24_04840	COG0720	synthase
HVZ24_04885	COG1857	crispr-associated protein
HVZ24_04900	COG1518	maintenance of DNA repeat elements
HVZ24_04905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_04910	COG2234	aminopeptidase activity
HVZ24_04965	COG4942	peptidase
HVZ24_04965	COG1388	LysM domain
HVZ24_04970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVZ24_04975	COG2610	gluconate transmembrane transporter activity
HVZ24_04980	COG3622	Belongs to the hyi family
HVZ24_04985	COG0235	Class ii aldolase
HVZ24_04990	COG3395	kinase activity
HVZ24_04995	COG2084	Dehydrogenase
HVZ24_05000	COG1349	DNA-binding transcription factor activity
HVZ24_05005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVZ24_05025	COG3604	Transcriptional regulator
HVZ24_05030	COG0309	Hydrogenase expression formation protein (HypE)
HVZ24_05035	COG0409	Hydrogenase expression formation protein
HVZ24_05040	COG0298	carbon dioxide binding
HVZ24_05045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HVZ24_05050	COG0375	protein maturation
HVZ24_05060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_05065	COG0651	ATP synthesis coupled electron transport
HVZ24_05070	COG0650	Formate hydrogenlyase subunit 4
HVZ24_05075	COG3261	NADH dehydrogenase
HVZ24_05075	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVZ24_05080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVZ24_05085	COG3260	NADH ubiquinone oxidoreductase 20
HVZ24_05095	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVZ24_05100	COG2723	6-phospho-beta-galactosidase activity
HVZ24_05105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_05105	COG1263	PTS System
HVZ24_05110	COG1609	Transcriptional regulator
HVZ24_05115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_05120	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HVZ24_05140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVZ24_05140	COG0517	IMP dehydrogenase activity
HVZ24_05145	COG1349	DNA-binding transcription factor activity
HVZ24_05150	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_05155	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_05160	COG3731	PTS system glucitol sorbitol-specific IIA component
HVZ24_05165	COG3732	PTS system glucitol sorbitol-specific
HVZ24_05170	COG3730	PTS system glucitol sorbitol-specific
HVZ24_05175	COG2951	lytic endotransglycosylase activity
HVZ24_05180	COG1546	Belongs to the CinA family
HVZ24_05200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HVZ24_05230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVZ24_05235	COG1238	metal cluster binding
HVZ24_05250	COG2814	Major facilitator Superfamily
HVZ24_05255	COG1566	PFAM secretion protein HlyD family protein
HVZ24_05260	COG1846	Transcriptional regulator
HVZ24_05270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HVZ24_05275	COG2814	Major facilitator Superfamily
HVZ24_05280	COG2113	Glycine betaine
HVZ24_05285	COG4176	ABC-type proline glycine betaine transport system permease component
HVZ24_05290	COG4175	Glycine betaine
HVZ24_05295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVZ24_05300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVZ24_05310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVZ24_05315	COG4575	ribosome binding
HVZ24_05330	COG2916	Histone family protein nucleoid-structuring protein H-NS
HVZ24_05335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVZ24_05340	COG0640	Transcriptional regulator
HVZ24_05345	COG0401	homolog of Blt101
HVZ24_05350	COG1652	LysM domain
HVZ24_05355	COG1802	Transcriptional regulator
HVZ24_05360	COG1113	amino acid transport
HVZ24_05365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HVZ24_05370	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_05375	COG0579	oxidoreductase
HVZ24_05390	COG0366	Alpha amylase catalytic
HVZ24_05415	COG3468	outer membrane autotransporter barrel domain protein
HVZ24_05430	COG3012	SEC-C Motif Domain Protein
HVZ24_05435	COG0582	viral genome integration into host DNA
HVZ24_05450	COG2867	negative regulation of translational initiation
HVZ24_05460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVZ24_05465	COG0497	DNA recombination
HVZ24_05480	COG4536	flavin adenine dinucleotide binding
HVZ24_05485	COG4137	Cytochrome C assembly protein
HVZ24_05490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HVZ24_05515	COG2885	chlorophyll binding
HVZ24_05520	COG2199	diguanylate cyclase activity
HVZ24_05535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVZ24_05540	COG1605	Chorismate mutase
HVZ24_05540	COG0287	Prephenate dehydrogenase
HVZ24_05545	COG0077	Prephenate dehydratase
HVZ24_05545	COG1605	Chorismate mutase
HVZ24_05555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVZ24_05560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVZ24_05565	COG0564	pseudouridine synthase activity
HVZ24_05575	COG0542	response to heat
HVZ24_05600	COG0477	Major facilitator Superfamily
HVZ24_05605	COG5544	Lipoprotein
HVZ24_05610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVZ24_05615	COG0045	succinate-CoA ligase (ADP-forming) activity
HVZ24_05615	COG1042	CoA-binding domain protein
HVZ24_05615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVZ24_05625	COG3118	belongs to the thioredoxin family
HVZ24_05630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVZ24_05650	COG0583	DNA-binding transcription factor activity
HVZ24_05655	COG0513	Belongs to the DEAD box helicase family
HVZ24_05665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HVZ24_05675	COG1595	DNA-templated transcription, initiation
HVZ24_05680	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HVZ24_05685	COG3026	antisigma factor binding
HVZ24_05690	COG3086	response to oxidative stress
HVZ24_05700	COG0681	Belongs to the peptidase S26 family
HVZ24_05720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HVZ24_05735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_05740	COG1737	Transcriptional regulator
HVZ24_05745	COG0560	Phosphoserine phosphatase
HVZ24_05760	COG0047	phosphoribosylformylglycinamidine synthase activity
HVZ24_05760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HVZ24_05765	COG2205	protein histidine kinase activity
HVZ24_05770	COG3170	Tfp pilus assembly protein FimV
HVZ24_05775	COG2204	response regulator
HVZ24_05780	COG0347	Belongs to the P(II) protein family
HVZ24_05785	COG1017	nitric oxide dioxygenase activity
HVZ24_05785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_05795	COG1940	carbohydrate kinase activity
HVZ24_05800	COG0457	Tetratricopeptide repeat
HVZ24_05805	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_05810	COG1129	ABC transporter
HVZ24_05815	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_05820	COG1063	alcohol dehydrogenase
HVZ24_05825	COG2017	converts alpha-aldose to the beta-anomer
HVZ24_05830	COG2259	Doxx family
HVZ24_05855	COG4638	Rieske (2fe-2S)
HVZ24_05860	COG0583	DNA-binding transcription factor activity
HVZ24_05865	COG2814	Major facilitator Superfamily
HVZ24_05870	COG3711	transcriptional antiterminator
HVZ24_05875	COG1073	alpha beta
HVZ24_05880	COG0483	inositol monophosphate 1-phosphatase activity
HVZ24_05900	COG0822	iron-sulfur transferase activity
HVZ24_05920	COG0633	Ferredoxin
HVZ24_05925	COG2975	iron-sulfur cluster assembly
HVZ24_05940	COG2897	thiosulfate sulfurtransferase activity
HVZ24_05945	COG2373	Large extracellular alpha-helical protein
HVZ24_05950	COG4953	penicillin-binding protein 1C
HVZ24_05980	COG2976	Protein conserved in bacteria
HVZ24_05995	COG1645	bacterial-type flagellum-dependent swarming motility
HVZ24_06005	COG0516	GMP reductase activity
HVZ24_06005	COG0517	IMP dehydrogenase activity
HVZ24_06020	COG3133	Outer membrane lipoprotein
HVZ24_06035	COG2200	EAL domain
HVZ24_06040	COG0248	Ppx GppA phosphatase
HVZ24_06045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HVZ24_06050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HVZ24_06065	COG2233	PERMEase
HVZ24_06075	COG1393	Belongs to the ArsC family
HVZ24_06080	COG4783	chaperone-mediated protein folding
HVZ24_06085	COG0628	permease
HVZ24_06090	COG2116	formate transmembrane transporter activity
HVZ24_06095	COG3604	Transcriptional regulator
HVZ24_06105	COG3260	NADH ubiquinone oxidoreductase 20
HVZ24_06110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVZ24_06115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVZ24_06115	COG3261	NADH dehydrogenase
HVZ24_06120	COG0651	ATP synthesis coupled electron transport
HVZ24_06125	COG4237	Hydrogenase 4 membrane
HVZ24_06130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVZ24_06135	COG0650	Formate hydrogenlyase subunit 4
HVZ24_06140	COG0651	ATP synthesis coupled electron transport
HVZ24_06145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_06150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HVZ24_06155	COG2716	regulation of RNA biosynthetic process
HVZ24_06165	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HVZ24_06175	COG2321	neutral zinc metallopeptidase
HVZ24_06180	COG1444	tRNA N-acetyltransferase activity
HVZ24_06185	COG0400	carboxylic ester hydrolase activity
HVZ24_06200	COG1393	Belongs to the ArsC family
HVZ24_06210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVZ24_06215	COG3850	Histidine kinase
HVZ24_06220	COG0493	'glutamate synthase
HVZ24_06220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_06230	COG5342	invasion associated locus B
HVZ24_06235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVZ24_06240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVZ24_06245	COG0281	malic enzyme
HVZ24_06245	COG0280	phosphate acetyltransferase
HVZ24_06250	COG4810	utilization protein
HVZ24_06255	COG4917	ethanolamine utilization protein
HVZ24_06260	COG4766	ethanolamine catabolic process
HVZ24_06265	COG4812	Cobalamin adenosyltransferase
HVZ24_06270	COG0280	phosphate acetyltransferase
HVZ24_06275	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVZ24_06280	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HVZ24_06285	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_06290	COG4820	ethanolamine utilization protein (EutJ)
HVZ24_06295	COG1454	alcohol dehydrogenase
HVZ24_06300	COG3192	ethanolamine utilization protein
HVZ24_06305	COG4819	ethanolamine utilization protein
HVZ24_06310	COG4303	Ethanolamine ammonia lyase large subunit
HVZ24_06320	COG4816	utilization protein
HVZ24_06325	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVZ24_06330	COG2207	Transcriptional regulator
HVZ24_06340	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVZ24_06345	COG0456	acetyltransferase
HVZ24_06360	COG2837	iron assimilation
HVZ24_06365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVZ24_06370	COG1263	PTS System
HVZ24_06370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_06385	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_06390	COG4150	thiosulfate binding
HVZ24_06395	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HVZ24_06400	COG4208	sulfate ABC transporter
HVZ24_06405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HVZ24_06410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVZ24_06415	COG3831	ATPase activity
HVZ24_06415	COG4884	unkown
HVZ24_06430	COG2190	(PTS) system
HVZ24_06435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVZ24_06440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_06445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVZ24_06465	COG3530	Putative quorum-sensing-regulated virulence factor
HVZ24_06470	COG0385	Bile acid
HVZ24_06475	COG0583	DNA-binding transcription factor activity
HVZ24_06485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HVZ24_06490	COG2211	Major facilitator Superfamily
HVZ24_06500	COG0583	DNA-binding transcription factor activity
HVZ24_06535	COG3415	Transposase
HVZ24_06540	COG3415	Transposase
HVZ24_06555	COG2199	diguanylate cyclase activity
HVZ24_06555	COG2200	EAL domain
HVZ24_06560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVZ24_06585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_06595	COG0006	proline dipeptidase activity
HVZ24_06600	COG1363	Peptidase, m42
HVZ24_06605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_06605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVZ24_06605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_06610	COG2207	Transcriptional regulator
HVZ24_06615	COG3279	Response regulator of the LytR AlgR family
HVZ24_06620	COG3275	phosphorelay sensor kinase activity
HVZ24_06625	COG0436	Aminotransferase
HVZ24_06635	COG1560	Kdo2-lipid A biosynthetic process
HVZ24_06660	COG0028	Belongs to the TPP enzyme family
HVZ24_06665	COG0679	Auxin Efflux Carrier
HVZ24_06670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HVZ24_06675	COG2205	protein histidine kinase activity
HVZ24_06675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_06675	COG2198	Histidine kinase
HVZ24_06675	COG0784	Response regulator, receiver
HVZ24_06680	COG2197	response regulator
HVZ24_06685	COG1566	PFAM secretion protein HlyD family protein
HVZ24_06690	COG0477	Major facilitator Superfamily
HVZ24_06700	COG2610	gluconate transmembrane transporter activity
HVZ24_06705	COG0583	DNA-binding transcription factor activity
HVZ24_06755	COG0582	viral genome integration into host DNA
HVZ24_06765	COG2116	formate transmembrane transporter activity
HVZ24_06770	COG2853	Lipoprotein
HVZ24_06780	COG2067	long-chain fatty acid transport protein
HVZ24_06785	COG3691	Protein conserved in bacteria
HVZ24_06800	COG2062	phosphohistidine phosphatase, SixA
HVZ24_06805	COG3539	Fimbrial protein
HVZ24_06810	COG3188	usher protein
HVZ24_06815	COG3121	Chaperone
HVZ24_06820	COG3539	Fimbrial protein
HVZ24_06825	COG3539	Fimbrial protein
HVZ24_06830	COG3539	Fimbrial protein
HVZ24_06845	COG2890	protein-(glutamine-N5) methyltransferase activity
HVZ24_06860	COG0730	response to heat
HVZ24_06865	COG3101	peptidyl-lysine hydroxylation
HVZ24_06880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVZ24_06885	COG2814	Major facilitator Superfamily
HVZ24_06900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVZ24_06910	COG0586	Pfam SNARE associated Golgi protein
HVZ24_06920	COG0285	dihydrofolate synthase activity
HVZ24_06925	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HVZ24_06930	COG1286	toxin biosynthetic process
HVZ24_06935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HVZ24_06940	COG0163	prenyltransferase activity
HVZ24_06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_06950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_06955	COG4215	(ABC) transporter
HVZ24_06960	COG4160	amino acid transport
HVZ24_06965	COG4598	ABC transporter
HVZ24_06970	COG5464	transposase or invertase
HVZ24_06975	COG1090	epimerase
HVZ24_06980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVZ24_06985	COG0625	glutathione transferase activity
HVZ24_06990	COG0625	glutathione transferase activity
HVZ24_06995	COG0622	Phosphoesterase
HVZ24_07000	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HVZ24_07005	COG1288	antiporter activity
HVZ24_07010	COG0857	belongs to the CobB CobQ family
HVZ24_07010	COG0280	phosphate acetyltransferase
HVZ24_07015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HVZ24_07030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVZ24_07035	COG0490	domain, Protein
HVZ24_07035	COG0471	metal ion transport
HVZ24_07045	COG0436	Aminotransferase
HVZ24_07050	COG0583	DNA-binding transcription factor activity
HVZ24_07070	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HVZ24_07075	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HVZ24_07080	COG1034	ATP synthesis coupled electron transport
HVZ24_07095	COG0839	Belongs to the complex I subunit 6 family
HVZ24_07105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVZ24_07110	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVZ24_07120	COG0457	Tetratricopeptide repeat
HVZ24_07140	COG2234	aminopeptidase activity
HVZ24_07145	COG2304	oxidoreductase activity
HVZ24_07150	COG5160	protein modification by small protein removal
HVZ24_07160	COG2153	protein acetylation
HVZ24_07165	COG4575	ribosome binding
HVZ24_07170	COG1169	isochorismate synthase
HVZ24_07185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HVZ24_07195	COG0318	PFAM AMP-dependent synthetase and ligase
HVZ24_07260	COG1414	Transcriptional regulator
HVZ24_07270	COG2271	Major facilitator Superfamily
HVZ24_07285	COG5464	transposase or invertase
HVZ24_07290	COG0247	lactate metabolic process
HVZ24_07300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVZ24_07305	COG2271	Major facilitator Superfamily
HVZ24_07310	COG0584	glycerophosphoryl diester phosphodiesterase
HVZ24_07320	COG3642	lipopolysaccharide core region biosynthetic process
HVZ24_07325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_07330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVZ24_07335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVZ24_07340	COG3468	outer membrane autotransporter barrel domain protein
HVZ24_07350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVZ24_07355	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HVZ24_07360	COG3234	Protein of unknown function (DUF1175)
HVZ24_07365	COG2373	Large extracellular alpha-helical protein
HVZ24_07370	COG5445	Predicted secreted protein (DUF2300)
HVZ24_07375	COG4676	Protein conserved in bacteria
HVZ24_07380	COG0183	Belongs to the thiolase family
HVZ24_07385	COG2031	fatty acid transporter
HVZ24_07390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HVZ24_07395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HVZ24_07400	COG2204	response regulator
HVZ24_07405	COG3852	Histidine kinase
HVZ24_07410	COG2205	protein histidine kinase activity
HVZ24_07410	COG0784	Response regulator, receiver
HVZ24_07415	COG2197	response regulator
HVZ24_07420	COG0642	Histidine kinase
HVZ24_07420	COG2198	Histidine kinase
HVZ24_07425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_07430	COG1477	protein flavinylation
HVZ24_07435	COG2169	Transcriptional regulator
HVZ24_07435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVZ24_07440	COG3145	DNA-N1-methyladenine dioxygenase activity
HVZ24_07445	COG4615	Cyclic peptide transporter
HVZ24_07465	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_07465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVZ24_07470	COG3062	negative regulation of establishment of protein localization
HVZ24_07480	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_07485	COG0348	domain, Protein
HVZ24_07490	COG3043	anaerobic respiration
HVZ24_07495	COG3005	denitrification pathway
HVZ24_07500	COG4133	protoheme IX ABC transporter activity
HVZ24_07505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVZ24_07510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVZ24_07515	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVZ24_07525	COG1138	Cytochrome C-type biogenesis protein
HVZ24_07530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HVZ24_07535	COG4235	cytochrome complex assembly
HVZ24_07535	COG3088	subunit of a heme lyase
HVZ24_07540	COG2197	response regulator
HVZ24_07555	COG3083	sulfuric ester hydrolase activity
HVZ24_07575	COG1061	Type III restriction enzyme res subunit
HVZ24_07580	COG1187	pseudouridine synthase activity
HVZ24_07585	COG2814	Major facilitator Superfamily
HVZ24_07595	COG4172	Belongs to the ABC transporter superfamily
HVZ24_07600	COG4239	(ABC) transporter, permease
HVZ24_07605	COG4174	ABC transporter (Permease)
HVZ24_07610	COG4166	transmembrane transport
HVZ24_07615	COG2200	EAL domain
HVZ24_07620	COG0791	NLP P60 protein
HVZ24_07625	COG0671	phosphoesterase, PA-phosphatase related
HVZ24_07630	COG0523	cobalamin synthesis protein
HVZ24_07635	COG0246	Mannitol dehydrogenase
HVZ24_07650	COG2814	Major facilitator Superfamily
HVZ24_07655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_07655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_07660	COG1105	Belongs to the carbohydrate kinase PfkB family
HVZ24_07665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_07665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HVZ24_07665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_07670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_07675	COG2313	pseudouridylate synthase activity
HVZ24_07680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVZ24_07685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVZ24_07695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVZ24_07700	COG1522	sequence-specific DNA binding
HVZ24_07700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_07710	COG2855	membrane
HVZ24_07715	COG0583	DNA-binding transcription factor activity
HVZ24_07720	COG0833	amino acid
HVZ24_07725	COG4771	TonB-dependent receptor
HVZ24_07740	COG2311	Membrane
HVZ24_07745	COG1609	Transcriptional regulator
HVZ24_07750	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_07755	COG1129	ABC transporter
HVZ24_07760	COG4211	Belongs to the binding-protein-dependent transport system permease family
HVZ24_07765	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HVZ24_07765	COG0167	dihydroorotate dehydrogenase activity
HVZ24_07770	COG0493	'glutamate synthase
HVZ24_07780	COG2949	membrane
HVZ24_07790	COG1346	cytolysis
HVZ24_07800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVZ24_07815	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_07820	COG0586	Pfam SNARE associated Golgi protein
HVZ24_07830	COG1686	Belongs to the peptidase S11 family
HVZ24_07835	COG0277	FAD linked oxidase domain protein
HVZ24_07840	COG1472	Belongs to the glycosyl hydrolase 3 family
HVZ24_07845	COG1732	Glycine betaine
HVZ24_07850	COG1174	glycine betaine transport
HVZ24_07855	COG1125	glycine betaine transport
HVZ24_07860	COG1174	glycine betaine transport
HVZ24_07870	COG0789	Transcriptional regulator
HVZ24_07875	COG3275	phosphorelay sensor kinase activity
HVZ24_07880	COG3279	Response regulator of the LytR AlgR family
HVZ24_07885	COG4807	Protein conserved in bacteria
HVZ24_07890	COG4808	Protein conserved in bacteria
HVZ24_07895	COG4715	Zinc finger, swim domain protein
HVZ24_07900	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HVZ24_07905	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HVZ24_07910	COG0714	Associated with various cellular activities
HVZ24_07920	COG3831	ATPase activity
HVZ24_07925	COG3831	ATPase activity
HVZ24_07930	COG3831	ATPase activity
HVZ24_07940	COG0489	protein tyrosine kinase activity
HVZ24_07950	COG3539	Fimbrial protein
HVZ24_07955	COG3121	Chaperone
HVZ24_07975	COG3539	Fimbrial protein
HVZ24_07980	COG5455	response to cobalt ion
HVZ24_08015	COG0351	phosphomethylpyrimidine kinase
HVZ24_08020	COG3757	hydrolase, family 25
HVZ24_08025	COG2188	Transcriptional regulator
HVZ24_08030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_08035	COG1397	ADP-ribosylglycohydrolase
HVZ24_08040	COG2211	Major facilitator Superfamily
HVZ24_08045	COG1830	Aldolase
HVZ24_08060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_08065	COG3414	Phosphotransferase system galactitol-specific IIB component
HVZ24_08070	COG3775	system Galactitol-specific IIC component
HVZ24_08075	COG1063	alcohol dehydrogenase
HVZ24_08165	COG3609	addiction module antidote protein, CC2985 family
HVZ24_08175	COG0745	RESPONSE REGULATOR receiver
HVZ24_08180	COG2205	protein histidine kinase activity
HVZ24_08215	COG4245	von Willebrand factor, type A
HVZ24_08220	COG0631	protein serine/threonine phosphatase activity
HVZ24_08225	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HVZ24_08230	COG0443	Heat shock 70 kDa protein
HVZ24_08235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HVZ24_08240	COG5001	Diguanylate cyclase
HVZ24_08240	COG5002	protein histidine kinase activity
HVZ24_08240	COG3447	MASE1 domain protein
HVZ24_08245	COG0572	uridine kinase
HVZ24_08255	COG2982	Protein involved in outer membrane biogenesis
HVZ24_08260	COG1253	flavin adenine dinucleotide binding
HVZ24_08265	COG1596	polysaccharide export
HVZ24_08270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HVZ24_08275	COG3206	protein involved in exopolysaccharide biosynthesis
HVZ24_08275	COG0489	protein tyrosine kinase activity
HVZ24_08280	COG0463	Glycosyl transferase, family 2
HVZ24_08285	COG1045	serine acetyltransferase
HVZ24_08290	COG0438	transferase activity, transferring glycosyl groups
HVZ24_08300	COG1216	Glycosyl transferase, family 2
HVZ24_08305	COG0110	maltose O-acetyltransferase activity
HVZ24_08310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HVZ24_08315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVZ24_08320	COG1051	belongs to the nudix hydrolase family
HVZ24_08325	COG0297	glycogen (starch) synthase activity
HVZ24_08330	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HVZ24_08330	COG0662	Cupin 2, conserved barrel domain protein
HVZ24_08335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HVZ24_08340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HVZ24_08345	COG2244	polysaccharide biosynthetic process
HVZ24_08350	COG2327	Polysaccharide pyruvyl transferase
HVZ24_08355	COG0438	transferase activity, transferring glycosyl groups
HVZ24_08365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVZ24_08370	COG1088	dTDP-glucose 4,6-dehydratase activity
HVZ24_08375	COG1091	dTDP-4-dehydrorhamnose reductase activity
HVZ24_08415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HVZ24_08430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HVZ24_08435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HVZ24_08440	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVZ24_08460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HVZ24_08465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVZ24_08465	COG0131	Imidazoleglycerol-phosphate dehydratase
HVZ24_08475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HVZ24_08490	COG2161	toxin-antitoxin pair type II binding
HVZ24_08495	COG4115	mRNA cleavage
HVZ24_08500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVZ24_08505	COG0583	DNA-binding transcription factor activity
HVZ24_08515	COG0531	amino acid
HVZ24_08520	COG2391	methyltransferase activity
HVZ24_08525	COG0425	Belongs to the sulfur carrier protein TusA family
HVZ24_08530	COG2925	Exonuclease
HVZ24_08535	COG1686	Belongs to the peptidase S11 family
HVZ24_08545	COG1289	transmembrane transporter activity
HVZ24_08590	COG2003	Belongs to the UPF0758 family
HVZ24_08640	COG3436	PFAM IS66 Orf2 family protein
HVZ24_08645	COG4372	Transposase
HVZ24_08695	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HVZ24_08710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_08720	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HVZ24_08735	COG1376	ErfK ybiS ycfS ynhG family protein
HVZ24_08745	COG0583	DNA-binding transcription factor activity
HVZ24_08750	COG0583	DNA-binding transcription factor activity
HVZ24_08760	COG0534	Mate efflux family protein
HVZ24_08770	COG0217	transcriptional regulatory protein
HVZ24_08775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HVZ24_08780	COG0477	Major facilitator Superfamily
HVZ24_08800	COG3209	COG3209 Rhs family protein
HVZ24_08815	COG3385	transposase activity
HVZ24_08845	COG3038	cytochrome b561
HVZ24_08850	COG3443	Belongs to the bacterial solute-binding protein 9 family
HVZ24_08865	COG2351	hydroxyisourate hydrolase activity
HVZ24_08870	COG0745	RESPONSE REGULATOR receiver
HVZ24_08875	COG2205	protein histidine kinase activity
HVZ24_08885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_08895	COG1418	mRNA catabolic process
HVZ24_08900	COG0270	DNA (cytosine-5-)-methyltransferase activity
HVZ24_08905	COG3727	T/G mismatch-specific endonuclease activity
HVZ24_08910	COG0697	spore germination
HVZ24_08915	COG2354	Protein conserved in bacteria
HVZ24_08920	COG5475	Uncharacterized small protein (DUF2158)
HVZ24_08945	COG2197	response regulator
HVZ24_08950	COG1684	flagellar biosynthetic protein fliR
HVZ24_08955	COG1987	bacterial-type flagellum assembly
HVZ24_08960	COG1338	Plays a role in the flagellum-specific transport system
HVZ24_08965	COG3190	flagellar
HVZ24_08970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVZ24_08975	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVZ24_08980	COG1580	Controls the rotational direction of flagella during chemotaxis
HVZ24_08985	COG3144	bacterial-type flagellum assembly
HVZ24_08990	COG2882	bacterial-type flagellum organization
HVZ24_08995	COG1157	protein secretion by the type III secretion system
HVZ24_09000	COG1317	bacterial-type flagellum organization
HVZ24_09005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVZ24_09010	COG1766	The M ring may be actively involved in energy transduction
HVZ24_09020	COG2135	peptidase activity
HVZ24_09025	COG0425	Belongs to the sulfur carrier protein TusA family
HVZ24_09030	COG2391	methyltransferase activity
HVZ24_09040	COG0366	Alpha amylase catalytic
HVZ24_09050	COG1516	flagellar protein fliS
HVZ24_09055	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HVZ24_09065	COG1191	sigma factor activity
HVZ24_09095	COG2197	response regulator
HVZ24_09110	COG2197	response regulator
HVZ24_09140	COG3012	SEC-C Motif Domain Protein
HVZ24_09140	COG3318	Belongs to the UPF0149 family
HVZ24_09145	COG0814	amino acid
HVZ24_09155	COG1528	Iron-storage protein
HVZ24_09175	COG1528	Iron-storage protein
HVZ24_09180	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_09185	COG1129	ABC transporter
HVZ24_09190	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_09195	COG1877	trehalose-phosphatase activity
HVZ24_09205	COG0589	response to stress
HVZ24_09220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HVZ24_09225	COG1360	Flagellar Motor Protein
HVZ24_09230	COG0643	Histidine kinase
HVZ24_09230	COG2198	Histidine kinase
HVZ24_09235	COG0835	chemotaxis
HVZ24_09240	COG0840	transmembrane signaling receptor activity
HVZ24_09245	COG0840	transmembrane signaling receptor activity
HVZ24_09250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HVZ24_09255	COG2201	protein-glutamate methylesterase activity
HVZ24_09260	COG0745	RESPONSE REGULATOR receiver
HVZ24_09265	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HVZ24_09270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HVZ24_09275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HVZ24_09285	COG3755	Protein conserved in bacteria
HVZ24_09295	COG3102	Protein conserved in bacteria
HVZ24_09305	COG3005	denitrification pathway
HVZ24_09310	COG0243	molybdopterin cofactor binding
HVZ24_09325	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HVZ24_09330	COG1801	Protein of unknown function DUF72
HVZ24_09335	COG1335	isochorismatase
HVZ24_09345	COG0494	nUDIX hydrolase
HVZ24_09350	COG0217	transcriptional regulatory protein
HVZ24_09380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HVZ24_09390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HVZ24_09395	COG0739	heme binding
HVZ24_09400	COG1560	Kdo2-lipid A biosynthetic process
HVZ24_09405	COG0469	pyruvate kinase activity
HVZ24_09410	COG1737	Transcriptional regulator
HVZ24_09415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HVZ24_09420	COG0129	dihydroxy-acid dehydratase activity
HVZ24_09425	COG0800	Aldolase
HVZ24_09435	COG3141	response to X-ray
HVZ24_09445	COG2979	Protein of unknown function (DUF533)
HVZ24_09450	COG1770	oligopeptidase
HVZ24_09455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_09460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVZ24_09470	COG2372	response to copper ion
HVZ24_09475	COG1276	copper resistance
HVZ24_09485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVZ24_09505	COG3008	intermembrane lipid transfer
HVZ24_09510	COG2995	paraquat-inducible protein a
HVZ24_09515	COG1956	GAF domain-containing protein
HVZ24_09525	COG0793	Belongs to the peptidase S41A family
HVZ24_09535	COG2814	Major facilitator Superfamily
HVZ24_09540	COG1414	Transcriptional regulator
HVZ24_09570	COG2226	methyltransferase
HVZ24_09585	COG3716	PTS system mannose fructose sorbose family IID component
HVZ24_09590	COG3715	PTS system
HVZ24_09595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_09595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_09600	COG1253	flavin adenine dinucleotide binding
HVZ24_09605	COG2200	EAL domain
HVZ24_09610	COG1760	l-serine dehydratase
HVZ24_09620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVZ24_09635	COG0251	oxidation-reduction process
HVZ24_09640	COG1199	ATP-dependent helicase activity
HVZ24_09645	COG1214	PFAM Peptidase M22, glycoprotease
HVZ24_09650	COG3065	identical protein binding
HVZ24_09655	COG0318	PFAM AMP-dependent synthetase and ligase
HVZ24_09660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HVZ24_09665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_09670	COG4638	Rieske (2fe-2S)
HVZ24_09680	COG0473	3-isopropylmalate dehydrogenase activity
HVZ24_09685	COG0583	DNA-binding transcription factor activity
HVZ24_09695	COG3615	Tellurite resistance protein tehB
HVZ24_09705	COG2261	transglycosylase associated protein
HVZ24_09720	COG2203	Gaf domain
HVZ24_09720	COG2199	diguanylate cyclase activity
HVZ24_09725	COG3042	response to heat
HVZ24_09730	COG3189	MarR family transcriptional regulator
HVZ24_09735	COG2807	transmembrane transport
HVZ24_09740	COG2207	Transcriptional regulator
HVZ24_09755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVZ24_09760	COG2199	diguanylate cyclase activity
HVZ24_09765	COG2199	diguanylate cyclase activity
HVZ24_09775	COG2766	serine protein kinase
HVZ24_09780	COG3713	MltA-interacting MipA family protein
HVZ24_09785	COG0656	L-ascorbic acid biosynthetic process
HVZ24_09790	COG0676	glucose-6-phosphate 1-epimerase activity
HVZ24_09795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HVZ24_09805	COG3139	Protein of unknown function (DUF1315)
HVZ24_09810	COG1063	alcohol dehydrogenase
HVZ24_09815	COG2271	Major facilitator Superfamily
HVZ24_09820	COG1063	alcohol dehydrogenase
HVZ24_09825	COG0191	fructose-bisphosphate aldolase activity
HVZ24_09830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_09835	COG0667	Aldo Keto reductase
HVZ24_09840	COG1349	DNA-binding transcription factor activity
HVZ24_09845	COG2814	Major facilitator Superfamily
HVZ24_09850	COG1335	isochorismatase
HVZ24_09855	COG0252	asparaginase activity
HVZ24_09860	COG0616	signal peptide processing
HVZ24_09865	COG0778	Nitroreductase
HVZ24_09875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVZ24_09885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HVZ24_09895	COG0494	nUDIX hydrolase
HVZ24_09900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HVZ24_09905	COG2897	thiosulfate sulfurtransferase activity
HVZ24_09910	COG4136	ATPase activity
HVZ24_09915	COG4135	transport system, permease component
HVZ24_09920	COG4134	Bacterial extracellular solute-binding protein
HVZ24_09925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVZ24_09930	COG0398	Pfam SNARE associated Golgi protein
HVZ24_09940	COG0398	Pfam SNARE associated Golgi protein
HVZ24_09945	COG0708	Exodeoxyribonuclease III
HVZ24_09975	COG3678	ATP-independent chaperone mediated protein folding
HVZ24_09985	COG0322	excinuclease ABC activity
HVZ24_09995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVZ24_10000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVZ24_10005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVZ24_10010	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVZ24_10015	COG1917	Cupin 2, conserved barrel domain protein
HVZ24_10015	COG2169	Transcriptional regulator
HVZ24_10020	COG1486	melibiose metabolic process
HVZ24_10030	COG0753	catalase activity
HVZ24_10050	COG1988	membrane-bound metal-dependent
HVZ24_10055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVZ24_10065	COG3001	Fructosamine kinase
HVZ24_10075	COG1105	Belongs to the carbohydrate kinase PfkB family
HVZ24_10080	COG3137	Salt-induced outer membrane protein
HVZ24_10125	COG0072	phenylalanine-tRNA ligase activity
HVZ24_10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HVZ24_10140	COG0386	Belongs to the glutathione peroxidase family
HVZ24_10150	COG0791	NLP P60 protein
HVZ24_10155	COG2200	EAL domain
HVZ24_10165	COG4256	Hemin uptake protein
HVZ24_10170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVZ24_10180	COG0574	Belongs to the PEP-utilizing enzyme family
HVZ24_10180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVZ24_10185	COG0318	PFAM AMP-dependent synthetase and ligase
HVZ24_10190	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVZ24_10195	COG0644	oxidoreductase
HVZ24_10200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HVZ24_10205	COG2086	electron transfer activity
HVZ24_10210	COG2207	Transcriptional regulator
HVZ24_10210	COG1917	Cupin 2, conserved barrel domain protein
HVZ24_10215	COG1960	acyl-CoA dehydrogenase activity
HVZ24_10220	COG4670	ketone body catabolic process
HVZ24_10235	COG2271	Major facilitator Superfamily
HVZ24_10240	COG0738	Major facilitator superfamily
HVZ24_10255	COG0628	permease
HVZ24_10260	COG0277	FAD linked oxidase domain protein
HVZ24_10260	COG0247	lactate metabolic process
HVZ24_10265	COG2050	protein possibly involved in aromatic compounds catabolism
HVZ24_10275	COG0316	Belongs to the HesB IscA family
HVZ24_10280	COG0719	Fe-S assembly protein
HVZ24_10285	COG0396	ATPase activity
HVZ24_10290	COG0719	Fe-S assembly protein
HVZ24_10305	COG1376	ErfK ybiS ycfS ynhG family protein
HVZ24_10310	COG4238	major outer membrane lipoprotein
HVZ24_10315	COG0469	pyruvate kinase activity
HVZ24_10325	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_10330	COG2414	aldehyde ferredoxin oxidoreductase
HVZ24_10340	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_10345	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HVZ24_10355	COG4529	Protein conserved in bacteria
HVZ24_10375	COG3468	outer membrane autotransporter barrel domain protein
HVZ24_10385	COG0307	riboflavin synthase, alpha
HVZ24_10390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HVZ24_10395	COG2814	Major facilitator Superfamily
HVZ24_10400	COG0583	DNA-binding transcription factor activity
HVZ24_10415	COG2814	Major facilitator Superfamily
HVZ24_10420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVZ24_10425	COG0791	NLP P60 protein
HVZ24_10430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HVZ24_10435	COG1201	RNA secondary structure unwinding
HVZ24_10440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_10445	COG0346	lactoylglutathione lyase activity
HVZ24_10450	COG1902	pentaerythritol trinitrate reductase activity
HVZ24_10455	COG1309	transcriptional regulator
HVZ24_10460	COG3313	Fe-S protein
HVZ24_10465	COG4989	oxidoreductase activity
HVZ24_10470	COG2032	superoxide dismutase activity
HVZ24_10475	COG1289	transmembrane transporter activity
HVZ24_10480	COG1566	PFAM secretion protein HlyD family protein
HVZ24_10495	COG3133	Outer membrane lipoprotein
HVZ24_10505	COG3895	Periplasmic Protein
HVZ24_10520	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HVZ24_10525	COG0625	glutathione transferase activity
HVZ24_10530	COG3104	oligopeptide transport
HVZ24_10535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HVZ24_10545	COG4659	FMN binding
HVZ24_10585	COG0673	inositol 2-dehydrogenase activity
HVZ24_10595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HVZ24_10600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_10600	COG1263	PTS System
HVZ24_10605	COG1609	Transcriptional regulator
HVZ24_10610	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_10615	COG1309	transcriptional regulator
HVZ24_10620	COG3250	beta-galactosidase activity
HVZ24_10635	COG5339	Protein conserved in bacteria
HVZ24_10640	COG1482	cell wall glycoprotein biosynthetic process
HVZ24_10645	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_10645	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_10650	COG0114	fumarate hydratase activity
HVZ24_10660	COG2205	protein histidine kinase activity
HVZ24_10665	COG0745	RESPONSE REGULATOR receiver
HVZ24_10670	COG3136	membrane protein required for alginate biosynthesis
HVZ24_10680	COG0531	amino acid
HVZ24_10690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HVZ24_10695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HVZ24_10700	COG0628	permease
HVZ24_10715	COG3591	Belongs to the peptidase S1B family
HVZ24_10730	COG2814	Major facilitator Superfamily
HVZ24_10735	COG0583	DNA-binding transcription factor activity
HVZ24_10740	COG1940	carbohydrate kinase activity
HVZ24_10745	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVZ24_10755	COG3381	protein complex oligomerization
HVZ24_10760	COG3302	dmso reductase anchor subunit
HVZ24_10765	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_10770	COG0243	molybdopterin cofactor binding
HVZ24_10775	COG0243	molybdopterin cofactor binding
HVZ24_10790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVZ24_10805	COG4948	Mandelate Racemase Muconate Lactonizing
HVZ24_10810	COG1063	alcohol dehydrogenase
HVZ24_10820	COG0582	viral genome integration into host DNA
HVZ24_10830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_10855	COG1396	sequence-specific DNA binding
HVZ24_10870	COG1846	Transcriptional regulator
HVZ24_10890	COG2801	Transposase and inactivated derivatives
HVZ24_10905	COG3077	Addiction module antitoxin, RelB DinJ family
HVZ24_10910	COG2026	Addiction module toxin, RelE StbE family
HVZ24_10930	COG1403	HNH endonuclease
HVZ24_10935	COG0484	heat shock protein binding
HVZ24_10945	COG1278	Cold shock
HVZ24_10950	COG1278	Cold shock
HVZ24_10965	COG3772	lysozyme
HVZ24_10975	COG1278	Cold shock
HVZ24_11000	COG5562	phage envelope protein
HVZ24_11010	COG4220	transposase activity
HVZ24_11030	COG1030	water channel activity
HVZ24_11080	COG1196	nuclear chromosome segregation
HVZ24_11115	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVZ24_11120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVZ24_11125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVZ24_11145	COG0246	Mannitol dehydrogenase
HVZ24_11155	COG1802	Transcriptional regulator
HVZ24_11160	COG4221	oxidoreductase activity
HVZ24_11165	COG0339	signal peptide processing
HVZ24_11170	COG1546	Belongs to the CinA family
HVZ24_11175	COG3111	PFAM Bacterial OB fold (BOF) protein
HVZ24_11180	COG3706	GGDEF domain
HVZ24_11190	COG2814	Major facilitator Superfamily
HVZ24_11195	COG0697	spore germination
HVZ24_11205	COG4977	sequence-specific DNA binding
HVZ24_11210	COG1846	Transcriptional regulator
HVZ24_11230	COG0583	DNA-binding transcription factor activity
HVZ24_11235	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_11240	COG2066	Belongs to the glutaminase family
HVZ24_11260	COG3781	membrane
HVZ24_11320	COG1396	sequence-specific DNA binding
HVZ24_11325	COG3550	peptidyl-serine autophosphorylation
HVZ24_11350	COG1396	sequence-specific DNA binding
HVZ24_11365	COG1074	ATP-dependent DNA helicase activity
HVZ24_11375	COG0653	protein targeting
HVZ24_11425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HVZ24_11430	COG3012	SEC-C Motif Domain Protein
HVZ24_11430	COG3318	Belongs to the UPF0149 family
HVZ24_11460	COG3539	Fimbrial protein
HVZ24_11465	COG3539	Fimbrial protein
HVZ24_11470	COG3539	Fimbrial protein
HVZ24_11475	COG0243	molybdopterin cofactor binding
HVZ24_11485	COG2207	Transcriptional regulator
HVZ24_11490	COG3119	arylsulfatase activity
HVZ24_11495	COG0641	radical SAM
HVZ24_11505	COG4178	(ABC) transporter
HVZ24_11510	COG4771	TonB-dependent receptor
HVZ24_11515	COG0612	Peptidase, M16
HVZ24_11520	COG0076	glutamate decarboxylase activity
HVZ24_11525	COG0531	amino acid
HVZ24_11540	COG3706	GGDEF domain
HVZ24_11545	COG2199	diguanylate cyclase activity
HVZ24_11545	COG2200	EAL domain
HVZ24_11545	COG2202	Pas domain
HVZ24_11550	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HVZ24_11560	COG0601	transmembrane transport
HVZ24_11565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVZ24_11570	COG0444	Belongs to the ABC transporter superfamily
HVZ24_11575	COG4608	Belongs to the ABC transporter superfamily
HVZ24_11580	COG1764	response to oxidative stress
HVZ24_11600	COG1064	alcohol dehydrogenase
HVZ24_11605	COG3093	addiction module antidote protein HigA
HVZ24_11610	COG2864	formate dehydrogenase
HVZ24_11615	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_11625	COG0697	spore germination
HVZ24_11630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_11640	COG2223	nitrite transmembrane transporter activity
HVZ24_11645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVZ24_11650	COG1140	nitrate reductase beta subunit
HVZ24_11655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVZ24_11660	COG2181	nitrate reductase activity
HVZ24_11665	COG0384	phenazine biosynthesis protein PhzF
HVZ24_11670	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HVZ24_11675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVZ24_11715	COG0625	glutathione transferase activity
HVZ24_11720	COG1113	amino acid transport
HVZ24_11725	COG3391	amine dehydrogenase activity
HVZ24_11730	COG4772	TonB-dependent receptor
HVZ24_11735	COG1802	Transcriptional regulator
HVZ24_11740	COG2130	NADP-dependent
HVZ24_11745	COG1247	-acetyltransferase
HVZ24_11750	COG3238	Protein conserved in bacteria
HVZ24_11775	COG1177	transmembrane transport
HVZ24_11780	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVZ24_11785	COG3842	ATPase activity
HVZ24_11790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVZ24_11795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HVZ24_11800	COG1598	PFAM Uncharacterised protein family UPF0150
HVZ24_11805	COG1724	mRNA binding
HVZ24_11815	COG0826	peptidase U32
HVZ24_11820	COG1396	sequence-specific DNA binding
HVZ24_11825	COG3135	benzoate transporter
HVZ24_11830	COG0675	Transposase, IS605 OrfB family
HVZ24_11845	COG0500	methyltransferase
HVZ24_11850	COG1275	C4-dicarboxylate transporter malic acid transport protein
HVZ24_11855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVZ24_11860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVZ24_11865	COG2841	Protein conserved in bacteria
HVZ24_11875	COG5383	Protein conserved in bacteria
HVZ24_11880	COG0583	DNA-binding transcription factor activity
HVZ24_11885	COG0840	transmembrane signaling receptor activity
HVZ24_11900	COG3038	cytochrome b561
HVZ24_11910	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_11915	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HVZ24_11920	COG1643	Atp-dependent helicase
HVZ24_11930	COG0671	phosphoesterase, PA-phosphatase related
HVZ24_11930	COG2453	phosphatase
HVZ24_11935	COG2267	carboxylic ester hydrolase activity
HVZ24_11940	COG4589	Belongs to the CDS family
HVZ24_11945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HVZ24_11955	COG0667	Aldo Keto reductase
HVZ24_11970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVZ24_11975	COG3327	negative regulation of DNA-templated transcription, initiation
HVZ24_11980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HVZ24_11985	COG0183	Belongs to the thiolase family
HVZ24_11990	COG2050	protein possibly involved in aromatic compounds catabolism
HVZ24_11995	COG1250	3-hydroxyacyl-CoA dehydrogenase
HVZ24_12000	COG1024	Enoyl-CoA hydratase
HVZ24_12005	COG1024	Enoyl-CoA hydratase
HVZ24_12010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_12015	COG2151	metal-sulfur cluster biosynthetic enzyme
HVZ24_12020	COG3396	Phenylacetate-CoA oxygenase
HVZ24_12025	COG3460	Phenylacetate-CoA oxygenase
HVZ24_12030	COG3396	Phenylacetate-CoA oxygenase
HVZ24_12035	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_12035	COG2030	dehydratase
HVZ24_12040	COG3733	amine oxidase
HVZ24_12045	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_12050	COG2207	Transcriptional regulator
HVZ24_12055	COG3784	Protein of unknown function (DUF1318)
HVZ24_12065	COG2911	Protein conserved in bacteria
HVZ24_12070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HVZ24_12075	COG3187	Heat shock protein
HVZ24_12080	COG3042	response to heat
HVZ24_12085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVZ24_12085	COG0674	pyruvate-flavodoxin oxidoreductase activity
HVZ24_12085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HVZ24_12085	COG1013	pyruvate-flavodoxin oxidoreductase activity
HVZ24_12090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_12095	COG0589	response to stress
HVZ24_12110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVZ24_12115	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVZ24_12135	COG1475	DNA binding
HVZ24_12140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVZ24_12195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HVZ24_12200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HVZ24_12215	COG1846	Transcriptional regulator
HVZ24_12220	COG1484	DNA-dependent DNA replication
HVZ24_12225	COG3756	Protein conserved in bacteria
HVZ24_12235	COG4197	protein conserved in bacteria, prophage-related
HVZ24_12270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_12275	COG3723	Recombinational DNA repair protein, rece pathway
HVZ24_12295	COG0582	viral genome integration into host DNA
HVZ24_12305	COG0513	Belongs to the DEAD box helicase family
HVZ24_12315	COG3706	GGDEF domain
HVZ24_12320	COG2840	Smr protein MutS2
HVZ24_12325	COG0583	DNA-binding transcription factor activity
HVZ24_12330	COG1473	amidohydrolase
HVZ24_12335	COG1473	amidohydrolase
HVZ24_12340	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HVZ24_12345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVZ24_12350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVZ24_12355	COG0589	response to stress
HVZ24_12360	COG3182	Iron-regulated membrane protein
HVZ24_12365	COG0668	transmembrane transport
HVZ24_12370	COG4166	transmembrane transport
HVZ24_12375	COG0583	DNA-binding transcription factor activity
HVZ24_12380	COG1073	alpha beta
HVZ24_12395	COG2866	Carboxypeptidase
HVZ24_12400	COG4948	Mandelate Racemase Muconate Lactonizing
HVZ24_12405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HVZ24_12410	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HVZ24_12420	COG3106	COG3106 Predicted ATPase
HVZ24_12425	COG1609	Transcriptional regulator
HVZ24_12435	COG3842	ATPase activity
HVZ24_12440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVZ24_12445	COG1554	hydrolase, family 65, central catalytic
HVZ24_12450	COG0673	inositol 2-dehydrogenase activity
HVZ24_12455	COG1082	Xylose isomerase domain protein TIM barrel
HVZ24_12460	COG1063	alcohol dehydrogenase
HVZ24_12465	COG0395	ABC-type sugar transport system, permease component
HVZ24_12470	COG1175	transmembrane transport
HVZ24_12475	COG1653	transport
HVZ24_12480	COG0366	Alpha amylase catalytic
HVZ24_12485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVZ24_12495	COG1983	PspC domain protein
HVZ24_12505	COG1842	Phage shock protein A
HVZ24_12510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HVZ24_12515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HVZ24_12520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HVZ24_12525	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_12530	COG1396	sequence-specific DNA binding
HVZ24_12530	COG1917	Cupin 2, conserved barrel domain protein
HVZ24_12535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HVZ24_12540	COG0174	glutamine synthetase
HVZ24_12550	COG0531	amino acid
HVZ24_12560	COG4166	transmembrane transport
HVZ24_12565	COG4168	peptide transport system, permease
HVZ24_12570	COG4171	peptide transport system, permease
HVZ24_12575	COG4172	Belongs to the ABC transporter superfamily
HVZ24_12580	COG4172	Belongs to the ABC transporter superfamily
HVZ24_12585	COG2852	Protein conserved in bacteria
HVZ24_12590	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HVZ24_12595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVZ24_12595	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVZ24_12610	COG5001	Diguanylate cyclase
HVZ24_12620	COG1349	DNA-binding transcription factor activity
HVZ24_12630	COG0023	Translation Initiation Factor
HVZ24_12640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HVZ24_12645	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HVZ24_12650	COG0671	phosphoesterase, PA-phosphatase related
HVZ24_12660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HVZ24_12680	COG0583	DNA-binding transcription factor activity
HVZ24_12685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVZ24_12695	COG0616	signal peptide processing
HVZ24_12700	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_12705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HVZ24_12710	COG1187	pseudouridine synthase activity
HVZ24_12715	COG4907	membrane protein (DUF2207)
HVZ24_12720	COG0009	L-threonylcarbamoyladenylate synthase
HVZ24_12725	COG0613	PHP domain protein
HVZ24_12735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVZ24_12740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVZ24_12740	COG0512	Glutamine amidotransferase of anthranilate synthase
HVZ24_12745	COG0135	phosphoribosylanthranilate isomerase activity
HVZ24_12745	COG0134	indole-3-glycerol-phosphate synthase activity
HVZ24_12760	COG3729	General stress protein
HVZ24_12765	COG3685	Protein conserved in bacteria
HVZ24_12770	COG3685	Protein conserved in bacteria
HVZ24_12775	COG3047	cAMP biosynthetic process
HVZ24_12795	COG1607	acyl-coa hydrolase
HVZ24_12800	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HVZ24_12805	COG2350	Protein conserved in bacteria
HVZ24_12810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVZ24_12830	COG4608	Belongs to the ABC transporter superfamily
HVZ24_12835	COG0444	Belongs to the ABC transporter superfamily
HVZ24_12840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVZ24_12845	COG0601	transmembrane transport
HVZ24_12850	COG4166	transmembrane transport
HVZ24_12860	COG2095	MarC family integral membrane protein
HVZ24_12865	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_12865	COG1454	alcohol dehydrogenase
HVZ24_12875	COG1435	thymidine kinase activity
HVZ24_12885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVZ24_12890	COG0745	RESPONSE REGULATOR receiver
HVZ24_12895	COG1752	Esterase of the alpha-beta hydrolase superfamily
HVZ24_12905	COG0788	formyltetrahydrofolate deformylase activity
HVZ24_12940	COG2181	nitrate reductase activity
HVZ24_12945	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVZ24_12950	COG1140	nitrate reductase beta subunit
HVZ24_12955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVZ24_12960	COG2223	nitrite transmembrane transporter activity
HVZ24_12965	COG3850	Histidine kinase
HVZ24_12970	COG2197	response regulator
HVZ24_12975	COG4932	domain protein
HVZ24_12980	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HVZ24_12985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HVZ24_12990	COG4572	Cation transport regulator
HVZ24_12995	COG0387	Pfam Sodium calcium exchanger
HVZ24_13020	COG2912	Transglutaminase-like superfamily
HVZ24_13025	COG3094	Invasion gene expression up-regulator, SirB
HVZ24_13030	COG2890	protein-(glutamine-N5) methyltransferase activity
HVZ24_13055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HVZ24_13060	COG0659	secondary active sulfate transmembrane transporter activity
HVZ24_13075	COG0012	GTP binding
HVZ24_13080	COG3468	outer membrane autotransporter barrel domain protein
HVZ24_13085	COG3284	Transcriptional regulator
HVZ24_13090	COG2376	Dihydroxyacetone kinase
HVZ24_13095	COG1461	Dihydroxyacetone kinase
HVZ24_13100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVZ24_13100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_13100	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HVZ24_13115	COG2261	transglycosylase associated protein
HVZ24_13120	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HVZ24_13130	COG1619	proteins homologs of microcin C7 resistance protein MccF
HVZ24_13140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVZ24_13150	COG2719	SpoVR family
HVZ24_13165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HVZ24_13170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HVZ24_13175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HVZ24_13190	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVZ24_13215	COG2894	cell division
HVZ24_13265	COG2200	EAL domain
HVZ24_13290	COG2200	EAL domain
HVZ24_13295	COG0789	Transcriptional regulator
HVZ24_13300	COG5562	phage envelope protein
HVZ24_13320	COG0538	isocitrate dehydrogenase activity
HVZ24_13325	COG1187	pseudouridine synthase activity
HVZ24_13345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HVZ24_13350	COG0745	RESPONSE REGULATOR receiver
HVZ24_13355	COG2205	protein histidine kinase activity
HVZ24_13360	COG2850	peptidyl-arginine hydroxylation
HVZ24_13370	COG3842	ATPase activity
HVZ24_13380	COG1177	transmembrane transport
HVZ24_13385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVZ24_13395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HVZ24_13400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HVZ24_13410	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVZ24_13415	COG1136	(ABC) transporter
HVZ24_13420	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVZ24_13425	COG4763	Acyl-transferase
HVZ24_13430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HVZ24_13435	COG1376	ErfK ybiS ycfS ynhG family protein
HVZ24_13435	COG1388	LysM domain
HVZ24_13445	COG1309	transcriptional regulator
HVZ24_13450	COG3134	Outer membrane lipoprotein
HVZ24_13455	COG1252	NADH dehydrogenase
HVZ24_13475	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HVZ24_13480	COG5633	Lipoprotein
HVZ24_13485	COG0537	adenosine 5'-monophosphoramidase activity
HVZ24_13490	COG4773	Receptor
HVZ24_13495	COG1263	PTS System
HVZ24_13495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_13500	COG0084	hydrolase, TatD family'
HVZ24_13505	COG0470	DNA polymerase III
HVZ24_13515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HVZ24_13520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVZ24_13525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVZ24_13535	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_13540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HVZ24_13560	COG1399	metal-binding, possibly nucleic acid-binding protein
HVZ24_13565	COG0424	maF-like protein
HVZ24_13570	COG0564	pseudouridine synthase activity
HVZ24_13575	COG1530	ribonuclease E activity
HVZ24_13580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HVZ24_13585	COG1256	bacterial-type flagellum assembly
HVZ24_13590	COG3951	Flagellar rod assembly protein muramidase FlgJ
HVZ24_13590	COG1705	Flagellar rod assembly protein muramidase FlgJ
HVZ24_13605	COG4786	Flagellar basal body rod
HVZ24_13610	COG4787	bacterial-type flagellum-dependent cell motility
HVZ24_13615	COG1749	Flagellar hook protein flgE
HVZ24_13620	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HVZ24_13625	COG1558	bacterial-type flagellum-dependent cell motility
HVZ24_13630	COG1815	bacterial-type flagellum-dependent cell motility
HVZ24_13635	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HVZ24_13640	COG2747	anti-sigma28 factor FlgM
HVZ24_13645	COG3418	PFAM FlgN family protein
HVZ24_13650	COG0728	peptidoglycan biosynthetic process
HVZ24_13655	COG0673	inositol 2-dehydrogenase activity
HVZ24_13665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVZ24_13675	COG2999	glutathione oxidoreductase activity
HVZ24_13710	COG3038	cytochrome b561
HVZ24_13715	COG2353	YceI-like domain
HVZ24_13725	COG1560	Kdo2-lipid A biosynthetic process
HVZ24_13740	COG5645	(Lipo)protein
HVZ24_13745	COG2943	transferase activity, transferring hexosyl groups
HVZ24_13760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVZ24_13765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVZ24_13790	COG2197	response regulator
HVZ24_13805	COG1462	curli production assembly transport component CsgG
HVZ24_13815	COG3381	protein complex oligomerization
HVZ24_13865	COG3706	GGDEF domain
HVZ24_13870	COG0457	Tetratricopeptide repeat
HVZ24_13875	COG1649	PFAM Uncharacterised BCR, COG1649
HVZ24_13875	COG0726	polysaccharide deacetylase
HVZ24_13880	COG1215	transferase activity, transferring glycosyl groups
HVZ24_13885	COG3658	cytochrome
HVZ24_13890	COG1702	phosphate starvation-inducible protein PhoH
HVZ24_13895	COG2837	iron assimilation
HVZ24_13900	COG2822	iron ion transport
HVZ24_13910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVZ24_13920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVZ24_13920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVZ24_13920	COG0506	proline dehydrogenase activity
HVZ24_13925	COG1309	transcriptional regulator
HVZ24_13960	COG2233	PERMEase
HVZ24_13965	COG3729	General stress protein
HVZ24_14000	COG3381	protein complex oligomerization
HVZ24_14005	COG0243	molybdopterin cofactor binding
HVZ24_14010	COG3005	denitrification pathway
HVZ24_14015	COG0745	RESPONSE REGULATOR receiver
HVZ24_14020	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_14025	COG2198	Histidine kinase
HVZ24_14025	COG2205	protein histidine kinase activity
HVZ24_14025	COG0784	Response regulator, receiver
HVZ24_14030	COG0348	domain, Protein
HVZ24_14050	COG1278	Cold shock
HVZ24_14055	COG1278	Cold shock
HVZ24_14080	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVZ24_14085	COG1596	polysaccharide export
HVZ24_14090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HVZ24_14095	COG0489	protein tyrosine kinase activity
HVZ24_14095	COG3206	protein involved in exopolysaccharide biosynthesis
HVZ24_14110	COG1294	oxidase, subunit
HVZ24_14115	COG1271	oxidase subunit
HVZ24_14120	COG1773	rubredoxin
HVZ24_14125	COG1999	signal sequence binding
HVZ24_14130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVZ24_14135	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HVZ24_14140	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVZ24_14145	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVZ24_14155	COG0670	Belongs to the BI1 family
HVZ24_14160	COG2920	part of a sulfur-relay system
HVZ24_14165	COG1254	Belongs to the acylphosphatase family
HVZ24_14180	COG1832	CoA-binding protein
HVZ24_14195	COG0210	DNA helicase
HVZ24_14200	COG3304	Inner membrane component domain
HVZ24_14205	COG1289	transmembrane transporter activity
HVZ24_14210	COG3070	regulator of competence-specific genes
HVZ24_14220	COG2885	chlorophyll binding
HVZ24_14220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HVZ24_14230	COG1067	ATP-dependent peptidase activity
HVZ24_14240	COG3130	regulation of translation
HVZ24_14245	COG3009	Protein conserved in bacteria
HVZ24_14250	COG3008	intermembrane lipid transfer
HVZ24_14250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVZ24_14255	COG2995	paraquat-inducible protein a
HVZ24_14260	COG0488	(ABC) transporter
HVZ24_14270	COG0633	Ferredoxin
HVZ24_14270	COG3217	Mosc domain protein beta barrel domain protein
HVZ24_14285	COG3121	Chaperone
HVZ24_14290	COG3539	Fimbrial protein
HVZ24_14295	COG3539	Fimbrial protein
HVZ24_14300	COG3539	Fimbrial protein
HVZ24_14305	COG3188	usher protein
HVZ24_14310	COG3121	Chaperone
HVZ24_14315	COG3539	Fimbrial protein
HVZ24_14320	COG0431	NADPH-dependent FMN reductase
HVZ24_14325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HVZ24_14335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVZ24_14340	COG1116	anion transmembrane transporter activity
HVZ24_14345	COG0308	aminopeptidase N
HVZ24_14360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_14365	COG1448	Aminotransferase
HVZ24_14370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HVZ24_14375	COG3108	Peptidase M15
HVZ24_14380	COG2989	Protein conserved in bacteria
HVZ24_14390	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HVZ24_14400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HVZ24_14405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HVZ24_14410	COG3173	Aminoglycoside phosphotransferase
HVZ24_14425	COG3214	Protein conserved in bacteria
HVZ24_14430	COG1663	tetraacyldisaccharide 4'-kinase activity
HVZ24_14435	COG1132	(ABC) transporter
HVZ24_14440	COG2333	competence protein COMEC
HVZ24_14440	COG0658	competence protein
HVZ24_14450	COG0539	negative regulation of cytoplasmic translation
HVZ24_14460	COG0501	Belongs to the peptidase M48B family
HVZ24_14475	COG2323	membrane
HVZ24_14480	COG1944	ATP diphosphatase activity
HVZ24_14485	COG2116	formate transmembrane transporter activity
HVZ24_14490	COG1882	Formate acetyltransferase
HVZ24_14495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVZ24_14500	COG2249	NAD(P)H dehydrogenase (quinone) activity
HVZ24_14505	COG0583	DNA-binding transcription factor activity
HVZ24_14510	COG0531	amino acid
HVZ24_14520	COG1335	isochorismatase
HVZ24_14525	COG3302	dmso reductase anchor subunit
HVZ24_14530	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_14535	COG0243	molybdopterin cofactor binding
HVZ24_14545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HVZ24_14555	COG1178	ABC-type Fe3 transport system permease component
HVZ24_14555	COG1674	ftsk spoiiie
HVZ24_14560	COG1522	sequence-specific DNA binding
HVZ24_14565	COG0492	ferredoxin-NADP+ reductase activity
HVZ24_14570	COG4988	ABC transporter
HVZ24_14575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HVZ24_14595	COG0542	response to heat
HVZ24_14605	COG1278	Cold shock
HVZ24_14610	COG1136	(ABC) transporter
HVZ24_14610	COG0577	efflux transmembrane transporter activity
HVZ24_14615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_14620	COG2990	Protein conserved in bacteria
HVZ24_14625	COG3593	DNA synthesis involved in DNA repair
HVZ24_14635	COG2431	L-lysine efflux transmembrane transporter activity
HVZ24_14645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_14650	COG0028	Belongs to the TPP enzyme family
HVZ24_14655	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HVZ24_14660	COG0702	epimerase
HVZ24_14665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVZ24_14670	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVZ24_14685	COG1126	abc transporter atp-binding protein
HVZ24_14690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_14695	COG4215	(ABC) transporter
HVZ24_14700	COG4160	amino acid transport
HVZ24_14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_14720	COG1177	transmembrane transport
HVZ24_14725	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVZ24_14730	COG3842	ATPase activity
HVZ24_14735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVZ24_14750	COG0778	Nitroreductase
HVZ24_14760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVZ24_14910	COG4695	Portal protein
HVZ24_14940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVZ24_14985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HVZ24_14990	COG3226	Transcriptional regulator
HVZ24_14995	COG0738	Major facilitator superfamily
HVZ24_15000	COG0561	phosphatase activity
HVZ24_15010	COG2814	Major facilitator Superfamily
HVZ24_15015	COG0671	phosphoesterase, PA-phosphatase related
HVZ24_15020	COG1349	DNA-binding transcription factor activity
HVZ24_15025	COG1686	Belongs to the peptidase S11 family
HVZ24_15030	COG0625	glutathione transferase activity
HVZ24_15035	COG2133	pyrroloquinoline quinone binding
HVZ24_15050	COG2199	diguanylate cyclase activity
HVZ24_15055	COG2200	EAL domain
HVZ24_15060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVZ24_15070	COG0747	negative chemotaxis
HVZ24_15075	COG4172	Belongs to the ABC transporter superfamily
HVZ24_15080	COG1446	asparaginase
HVZ24_15085	COG0303	'Molybdopterin
HVZ24_15090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVZ24_15095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVZ24_15100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVZ24_15105	COG1882	Formate acetyltransferase
HVZ24_15110	COG0561	phosphatase activity
HVZ24_15120	COG0488	(ABC) transporter
HVZ24_15125	COG1376	ErfK ybiS ycfS ynhG family protein
HVZ24_15130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HVZ24_15135	COG1321	iron dependent repressor
HVZ24_15145	COG2194	sulfuric ester hydrolase activity
HVZ24_15150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HVZ24_15160	COG5006	permease, DMT superfamily
HVZ24_15170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_15175	COG0765	amino acid transport
HVZ24_15180	COG1126	abc transporter atp-binding protein
HVZ24_15185	COG0668	transmembrane transport
HVZ24_15200	COG4774	siderophore transport
HVZ24_15210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVZ24_15220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVZ24_15225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVZ24_15230	COG1199	ATP-dependent helicase activity
HVZ24_15235	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HVZ24_15240	COG0513	Belongs to the DEAD box helicase family
HVZ24_15245	COG1309	transcriptional regulator
HVZ24_15255	COG1131	(ABC) transporter
HVZ24_15260	COG0842	Transport permease protein
HVZ24_15265	COG0842	Transport permease protein
HVZ24_15275	COG3568	Endonuclease Exonuclease Phosphatase
HVZ24_15280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVZ24_15285	COG0392	lysyltransferase activity
HVZ24_15290	COG0670	Belongs to the BI1 family
HVZ24_15295	COG0670	Belongs to the BI1 family
HVZ24_15300	COG0314	molybdopterin synthase activity
HVZ24_15305	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HVZ24_15315	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVZ24_15325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HVZ24_15335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVZ24_15340	COG2226	methyltransferase
HVZ24_15355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HVZ24_15360	COG1881	PFAM PEBP family protein
HVZ24_15365	COG2246	polysaccharide biosynthetic process
HVZ24_15370	COG0463	Glycosyl transferase, family 2
HVZ24_15475	COG0582	viral genome integration into host DNA
HVZ24_15480	COG4677	pectinesterase activity
HVZ24_15490	COG0471	metal ion transport
HVZ24_15495	COG2828	Protein conserved in bacteria
HVZ24_15500	COG0583	DNA-binding transcription factor activity
HVZ24_15510	COG0561	phosphatase activity
HVZ24_15515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HVZ24_15520	COG4149	molybdate abc transporter
HVZ24_15525	COG0725	ABC transporter, periplasmic molybdate-binding protein
HVZ24_15535	COG3585	molybdate ion transport
HVZ24_15535	COG2005	Transcriptional regulator
HVZ24_15540	COG1119	ATPase activity
HVZ24_15545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HVZ24_15550	COG1085	galactose-1-phosphate uridylyltransferase
HVZ24_15560	COG2017	converts alpha-aldose to the beta-anomer
HVZ24_15570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVZ24_15580	COG1230	cation diffusion facilitator family transporter
HVZ24_15585	COG3201	nicotinamide mononucleotide transporter
HVZ24_15635	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HVZ24_15640	COG2885	chlorophyll binding
HVZ24_15650	COG3064	Membrane
HVZ24_15655	COG0848	biopolymer transport protein
HVZ24_15660	COG0811	peptide transport
HVZ24_15665	COG0824	Thioesterase
HVZ24_15670	COG3790	cyd operon protein YbgE
HVZ24_15675	COG4890	Cyd operon protein YbgT
HVZ24_15680	COG1294	oxidase, subunit
HVZ24_15685	COG1271	oxidase subunit
HVZ24_15690	COG0383	alpha-mannosidase activity
HVZ24_15695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_15695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_15695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_15700	COG2188	Transcriptional regulator
HVZ24_15705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVZ24_15715	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVZ24_15720	COG0567	Dehydrogenase, E1 component
HVZ24_15725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVZ24_15730	COG1053	succinate dehydrogenase
HVZ24_15735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HVZ24_15740	COG2009	succinate dehydrogenase
HVZ24_15750	COG0372	Belongs to the citrate synthase family
HVZ24_15755	COG3539	Fimbrial protein
HVZ24_15760	COG3188	usher protein
HVZ24_15765	COG3121	Chaperone
HVZ24_15770	COG3539	Fimbrial protein
HVZ24_15775	COG3180	Ammonia monooxygenase
HVZ24_15790	COG1984	allophanate hydrolase subunit 2
HVZ24_15795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HVZ24_15800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HVZ24_15805	COG3104	oligopeptide transport
HVZ24_15810	COG0415	Belongs to the DNA photolyase family
HVZ24_15815	COG3272	Protein of unknown function (DUF1722)
HVZ24_15840	COG3209	COG3209 Rhs family protein
HVZ24_15850	COG3209	COG3209 Rhs family protein
HVZ24_15880	COG2205	protein histidine kinase activity
HVZ24_15885	COG0745	RESPONSE REGULATOR receiver
HVZ24_15895	COG1982	Orn Lys Arg decarboxylase major
HVZ24_15900	COG0531	amino acid
HVZ24_15920	COG0033	Phosphoglucomutase
HVZ24_15925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HVZ24_15930	COG0596	Alpha beta hydrolase
HVZ24_15940	COG0716	FMN binding
HVZ24_15950	COG0735	belongs to the Fur family
HVZ24_15970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_15970	COG1263	PTS System
HVZ24_15970	COG2190	(PTS) system
HVZ24_15980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVZ24_15985	COG1940	carbohydrate kinase activity
HVZ24_15985	COG1846	Transcriptional regulator
HVZ24_15990	COG0647	UMP catabolic process
HVZ24_15995	COG0367	asparagine synthase
HVZ24_16035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVZ24_16045	COG1702	phosphate starvation-inducible protein PhoH
HVZ24_16055	COG4535	Mg2 and Co2 transporter CorC
HVZ24_16060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HVZ24_16065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVZ24_16070	COG0765	amino acid transport
HVZ24_16075	COG0765	amino acid transport
HVZ24_16080	COG1126	abc transporter atp-binding protein
HVZ24_16090	COG0443	Heat shock 70 kDa protein
HVZ24_16095	COG2214	Heat shock protein DnaJ domain protein
HVZ24_16105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVZ24_16110	COG2214	Heat shock protein DnaJ domain protein
HVZ24_16120	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVZ24_16125	COG2888	peptidyl-tyrosine sulfation
HVZ24_16140	COG1466	dna polymerase III delta subunit
HVZ24_16150	COG0406	alpha-ribazole phosphatase activity
HVZ24_16155	COG0799	negative regulation of ribosome biogenesis
HVZ24_16165	COG0768	penicillin binding
HVZ24_16170	COG0772	Belongs to the SEDS family
HVZ24_16175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVZ24_16180	COG1686	Belongs to the peptidase S11 family
HVZ24_16195	COG0583	DNA-binding transcription factor activity
HVZ24_16205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVZ24_16230	COG3069	C4-dicarboxylate transmembrane transporter activity
HVZ24_16235	COG4565	transcriptional regulatory protein
HVZ24_16240	COG3290	protein histidine kinase activity
HVZ24_16245	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HVZ24_16255	COG2301	Belongs to the HpcH HpaI aldolase family
HVZ24_16260	COG3051	citrate lyase alpha subunit
HVZ24_16275	COG0471	metal ion transport
HVZ24_16280	COG3719	Belongs to the RNase T2 family
HVZ24_16285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVZ24_16290	COG1063	alcohol dehydrogenase
HVZ24_16295	COG0589	response to stress
HVZ24_16300	COG3634	alkyl hydroperoxide reductase activity
HVZ24_16305	COG0450	alkyl hydroperoxide reductase
HVZ24_16310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVZ24_16315	COG0583	DNA-binding transcription factor activity
HVZ24_16320	COG3969	phosphoadenosine phosphosulfate
HVZ24_16325	COG1475	DNA binding
HVZ24_16330	COG0436	Aminotransferase
HVZ24_16335	COG0371	Dehydrogenase
HVZ24_16340	COG2879	small protein
HVZ24_16345	COG1966	Carbon starvation protein
HVZ24_16350	COG2050	protein possibly involved in aromatic compounds catabolism
HVZ24_16355	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_16360	COG3433	isochorismatase activity
HVZ24_16360	COG1535	isochorismatase
HVZ24_16365	COG1021	2,3-dihydroxybenzoate-AMP ligase
HVZ24_16370	COG1169	isochorismate synthase
HVZ24_16375	COG4592	Periplasmic binding protein
HVZ24_16385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVZ24_16390	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVZ24_16395	COG1120	ATPase activity
HVZ24_16400	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVZ24_16405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HVZ24_16405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HVZ24_16410	COG3251	PFAM MbtH domain protein
HVZ24_16415	COG2382	esterase
HVZ24_16420	COG4771	TonB-dependent receptor
HVZ24_16425	COG2977	Belongs to the P-Pant transferase superfamily
HVZ24_16430	COG3385	transposase activity
HVZ24_16450	COG2315	Protein conserved in bacteria
HVZ24_16455	COG0778	Nitroreductase
HVZ24_16460	COG0668	transmembrane transport
HVZ24_16465	COG1113	amino acid transport
HVZ24_16470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVZ24_16475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_16480	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_16485	COG1538	Outer membrane efflux protein
HVZ24_16490	COG0745	RESPONSE REGULATOR receiver
HVZ24_16495	COG5002	protein histidine kinase activity
HVZ24_16500	COG1215	transferase activity, transferring glycosyl groups
HVZ24_16505	COG4783	chaperone-mediated protein folding
HVZ24_16515	COG2207	Transcriptional regulator
HVZ24_16520	COG4571	Outer membrane protease
HVZ24_16525	COG2207	Transcriptional regulator
HVZ24_16540	COG4220	transposase activity
HVZ24_16555	COG5562	phage envelope protein
HVZ24_16570	COG3772	lysozyme
HVZ24_16620	COG2207	Transcriptional regulator
HVZ24_16625	COG1881	PFAM PEBP family protein
HVZ24_16630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVZ24_16640	COG2076	Multidrug Resistance protein
HVZ24_16665	COG2197	response regulator
HVZ24_16670	COG3539	Fimbrial protein
HVZ24_16675	COG3539	Fimbrial protein
HVZ24_16680	COG3188	usher protein
HVZ24_16685	COG3121	Chaperone
HVZ24_16690	COG3539	Fimbrial protein
HVZ24_16700	COG2501	S4 domain
HVZ24_16705	COG1988	membrane-bound metal-dependent
HVZ24_16715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HVZ24_16725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HVZ24_16730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HVZ24_16735	COG0549	Belongs to the carbamate kinase family
HVZ24_16745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVZ24_16750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVZ24_16755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVZ24_16760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HVZ24_16765	COG3257	ureidoglycine aminohydrolase activity
HVZ24_16770	COG1929	Belongs to the glycerate kinase type-1 family
HVZ24_16775	COG2233	PERMEase
HVZ24_16785	COG1953	Uracil, thiamine, allantoin
HVZ24_16790	COG2084	Dehydrogenase
HVZ24_16795	COG3622	Belongs to the hyi family
HVZ24_16800	COG3960	tartronate-semialdehyde synthase activity
HVZ24_16805	COG1414	Transcriptional regulator
HVZ24_16815	COG0583	DNA-binding transcription factor activity
HVZ24_16840	COG3209	COG3209 Rhs family protein
HVZ24_16850	COG3209	COG3209 Rhs family protein
HVZ24_16855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HVZ24_16860	COG4181	ATPase activity
HVZ24_16865	COG2755	lipolytic protein G-D-S-L family
HVZ24_16870	COG0300	oxidoreductase activity
HVZ24_16875	COG3118	belongs to the thioredoxin family
HVZ24_16880	COG0390	transport system, permease component
HVZ24_16885	COG4619	ABC transporter
HVZ24_16890	COG0330	HflC and HflK could
HVZ24_16895	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVZ24_16900	COG0789	Transcriptional regulator
HVZ24_16905	COG0531	amino acid
HVZ24_16910	COG2066	Belongs to the glutaminase family
HVZ24_16915	COG2217	Heavy metal translocating P-type atpase
HVZ24_16920	COG3093	addiction module antidote protein HigA
HVZ24_16925	COG3735	TraB family
HVZ24_16930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVZ24_16935	COG0737	Belongs to the 5'-nucleotidase family
HVZ24_16940	COG2223	nitrite transmembrane transporter activity
HVZ24_16945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVZ24_16945	COG4651	solute:proton antiporter activity
HVZ24_16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_16985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HVZ24_16995	COG2832	Protein of unknown function (DUF454)
HVZ24_17000	COG3923	Primosomal replication protein n
HVZ24_17010	COG1196	nuclear chromosome segregation
HVZ24_17010	COG3264	Mechanosensitive ion channel
HVZ24_17015	COG1309	transcriptional regulator
HVZ24_17020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVZ24_17025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVZ24_17040	COG0110	maltose O-acetyltransferase activity
HVZ24_17055	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HVZ24_17060	COG5507	3-demethylubiquinone-9 3-methyltransferase
HVZ24_17070	COG3695	enzyme binding
HVZ24_17075	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HVZ24_17080	COG1946	Acyl-CoA thioesterase
HVZ24_17085	COG0004	ammonium transporteR
HVZ24_17090	COG0347	Belongs to the P(II) protein family
HVZ24_17095	COG1132	(ABC) transporter
HVZ24_17100	COG1132	(ABC) transporter
HVZ24_17105	COG1522	sequence-specific DNA binding
HVZ24_17115	COG4533	DNA binding
HVZ24_17125	COG0824	Thioesterase
HVZ24_17130	COG1555	photosystem II stabilization
HVZ24_17135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVZ24_17140	COG0776	regulation of translation
HVZ24_17145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HVZ24_17165	COG0271	Belongs to the BolA IbaG family
HVZ24_17170	COG3056	Lipoprotein
HVZ24_17175	COG2223	nitrite transmembrane transporter activity
HVZ24_17180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HVZ24_17185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HVZ24_17190	COG1845	cytochrome c oxidase, subunit III
HVZ24_17195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HVZ24_17205	COG2814	Major facilitator Superfamily
HVZ24_17215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HVZ24_17220	COG0693	protein deglycase activity
HVZ24_17235	COG0142	geranyltranstransferase activity
HVZ24_17245	COG0667	Aldo Keto reductase
HVZ24_17250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HVZ24_17255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HVZ24_17270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVZ24_17270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVZ24_17280	COG4238	major outer membrane lipoprotein
HVZ24_17285	COG3248	Nucleoside-binding outer membrane protein
HVZ24_17290	COG1403	HNH endonuclease
HVZ24_17295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVZ24_17300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVZ24_17305	COG1862	Preprotein translocase
HVZ24_17325	COG0366	Alpha amylase catalytic
HVZ24_17330	COG1113	amino acid transport
HVZ24_17335	COG1114	Component of the transport system for branched-chain amino acids
HVZ24_17340	COG5002	protein histidine kinase activity
HVZ24_17345	COG0745	RESPONSE REGULATOR receiver
HVZ24_17350	COG0420	3'-5' exonuclease activity
HVZ24_17355	COG0419	ATPase involved in DNA repair
HVZ24_17360	COG2814	Major facilitator Superfamily
HVZ24_17365	COG1940	carbohydrate kinase activity
HVZ24_17390	COG4126	flavin adenine dinucleotide binding
HVZ24_17410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HVZ24_17415	COG3706	GGDEF domain
HVZ24_17425	COG1785	Belongs to the alkaline phosphatase family
HVZ24_17440	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVZ24_17460	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HVZ24_17465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVZ24_17470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVZ24_17475	COG3468	outer membrane autotransporter barrel domain protein
HVZ24_17480	COG0113	porphobilinogen synthase activity
HVZ24_17485	COG2175	clavaminate synthase activity
HVZ24_17490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVZ24_17500	COG4521	taurine ABC transporter
HVZ24_17505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HVZ24_17510	COG1215	transferase activity, transferring glycosyl groups
HVZ24_17540	COG3122	Protein conserved in bacteria
HVZ24_17545	COG2814	Major facilitator Superfamily
HVZ24_17560	COG3971	2-oxopent-4-enoate hydratase activity
HVZ24_17580	COG1414	Transcriptional regulator
HVZ24_17585	COG1609	Transcriptional regulator
HVZ24_17590	COG3250	beta-galactosidase activity
HVZ24_17595	COG2223	nitrite transmembrane transporter activity
HVZ24_17600	COG0110	maltose O-acetyltransferase activity
HVZ24_17605	COG2807	transmembrane transport
HVZ24_17615	COG0288	reversible hydration of carbon dioxide
HVZ24_17620	COG0583	DNA-binding transcription factor activity
HVZ24_17625	COG0402	S-adenosylhomocysteine deaminase activity
HVZ24_17630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HVZ24_17635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVZ24_17640	COG2079	MmgE PrpD family protein
HVZ24_17645	COG0372	Belongs to the citrate synthase family
HVZ24_17650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HVZ24_17665	COG1280	lysine exporter protein (LysE YggA)
HVZ24_17680	COG1064	alcohol dehydrogenase
HVZ24_17685	COG0402	S-adenosylhomocysteine deaminase activity
HVZ24_17690	COG0549	Belongs to the carbamate kinase family
HVZ24_17700	COG1304	FMN binding
HVZ24_17705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVZ24_17715	COG0666	response to abiotic stimulus
HVZ24_17725	COG0583	DNA-binding transcription factor activity
HVZ24_17730	COG2771	luxR family
HVZ24_17730	COG2200	EAL domain
HVZ24_17740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HVZ24_17765	COG1556	Lactate utilization protein
HVZ24_17770	COG1139	Iron-sulfur cluster binding protein
HVZ24_17775	COG0247	lactate metabolic process
HVZ24_17780	COG2207	Transcriptional regulator
HVZ24_17785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVZ24_17795	COG3059	membrane
HVZ24_17805	COG3708	Transcriptional regulator
HVZ24_17805	COG2207	Transcriptional regulator
HVZ24_17810	COG1388	LysM domain
HVZ24_17850	COG3188	usher protein
HVZ24_17860	COG3121	Chaperone
HVZ24_17865	COG0727	PFAM Uncharacterised protein family (UPF0153)
HVZ24_17870	COG3477	response to acidic pH
HVZ24_17875	COG2080	2 iron, 2 sulfur cluster binding
HVZ24_17880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVZ24_17885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVZ24_17890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HVZ24_17895	COG0583	DNA-binding transcription factor activity
HVZ24_17920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HVZ24_17955	COG0438	transferase activity, transferring glycosyl groups
HVZ24_17960	COG0438	transferase activity, transferring glycosyl groups
HVZ24_17960	COG0297	glycogen (starch) synthase activity
HVZ24_18015	COG3846	protein secretion by the type IV secretion system
HVZ24_18035	COG3093	addiction module antidote protein HigA
HVZ24_18070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVZ24_18090	COG2195	Cleaves the N-terminal amino acid of tripeptides
HVZ24_18095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVZ24_18100	COG1690	Belongs to the RtcB family
HVZ24_18105	COG0454	-acetyltransferase
HVZ24_18115	COG2161	toxin-antitoxin pair type II binding
HVZ24_18135	COG1943	Transposase
HVZ24_18140	COG0791	NLP P60 protein
HVZ24_18145	COG3077	Addiction module antitoxin, RelB DinJ family
HVZ24_18150	COG3041	Addiction module toxin RelE StbE family
HVZ24_18155	COG3034	peptidoglycan biosynthetic process
HVZ24_18160	COG0121	glutamine amidotransferase
HVZ24_18170	COG1960	acyl-CoA dehydrogenase activity
HVZ24_18180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVZ24_18185	COG5433	transposase activity
HVZ24_18195	COG3209	COG3209 Rhs family protein
HVZ24_18210	COG3157	Type VI secretion system effector, Hcp
HVZ24_18215	COG4104	PAAR repeat-containing protein
HVZ24_18235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVZ24_18245	COG2226	methyltransferase
HVZ24_18255	COG1388	LysM domain
HVZ24_18255	COG0741	lytic transglycosylase activity
HVZ24_18270	COG0583	DNA-binding transcription factor activity
HVZ24_18275	COG0656	L-ascorbic acid biosynthetic process
HVZ24_18310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVZ24_18315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HVZ24_18320	COG2011	ABC-type metal ion transport system permease component
HVZ24_18325	COG1464	Belongs to the NlpA lipoprotein family
HVZ24_18335	COG1720	tRNA m6t6A37 methyltransferase activity
HVZ24_18345	COG0791	NLP P60 protein
HVZ24_18350	COG3015	lipoprotein NlpE involved in copper resistance
HVZ24_18355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVZ24_18360	COG4681	YaeQ
HVZ24_18370	COG4568	rho-dependent transcription termination
HVZ24_18375	COG0037	tRNA processing
HVZ24_18380	COG0346	lactoylglutathione lyase activity
HVZ24_18395	COG0587	DNA-directed DNA polymerase activity
HVZ24_18420	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HVZ24_18425	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HVZ24_18435	COG0750	zinc metalloprotease
HVZ24_18440	COG0575	Belongs to the CDS family
HVZ24_18445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HVZ24_18450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HVZ24_18475	COG0024	Methionine aminopeptidase
HVZ24_18490	COG1408	metallophosphoesterase
HVZ24_18500	COG3835	regulator
HVZ24_18505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVZ24_18520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVZ24_18525	COG2860	membrane
HVZ24_18550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVZ24_18555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVZ24_18560	COG1120	ATPase activity
HVZ24_18565	COG4774	siderophore transport
HVZ24_18570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HVZ24_18575	COG1643	Atp-dependent helicase
HVZ24_18580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HVZ24_18590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVZ24_18600	COG0617	tRNA 3'-terminal CCA addition
HVZ24_18605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HVZ24_18610	COG3539	Fimbrial protein
HVZ24_18615	COG3121	Chaperone
HVZ24_18620	COG3188	usher protein
HVZ24_18625	COG3539	Fimbrial protein
HVZ24_18630	COG3539	Fimbrial protein
HVZ24_18635	COG3539	Fimbrial protein
HVZ24_18640	COG3539	Fimbrial protein
HVZ24_18655	COG5464	transposase or invertase
HVZ24_18665	COG0726	polysaccharide deacetylase
HVZ24_18670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_18675	COG0842	Transport permease protein
HVZ24_18680	COG1131	(ABC) transporter
HVZ24_18685	COG0288	reversible hydration of carbon dioxide
HVZ24_18690	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HVZ24_18695	COG4993	Dehydrogenase
HVZ24_18700	COG2132	Multicopper oxidase
HVZ24_18725	COG1049	propionate catabolic process, 2-methylcitrate cycle
HVZ24_18730	COG3064	Membrane
HVZ24_18735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVZ24_18740	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVZ24_18745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HVZ24_18750	COG2186	Transcriptional regulator
HVZ24_18755	COG1113	amino acid transport
HVZ24_18760	COG3725	Membrane protein required for beta-lactamase induction
HVZ24_18765	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVZ24_18770	COG0157	Belongs to the NadC ModD family
HVZ24_18775	COG4969	Belongs to the N-Me-Phe pilin family
HVZ24_18780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVZ24_18785	COG1459	type II secretion system
HVZ24_18800	COG0237	dephospho-CoA kinase activity
HVZ24_18815	COG0494	nUDIX hydrolase
HVZ24_18835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HVZ24_18840	COG0849	cell division
HVZ24_18845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HVZ24_18850	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVZ24_18865	COG0772	Belongs to the SEDS family
HVZ24_18870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HVZ24_18880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HVZ24_18885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HVZ24_18890	COG0768	penicillin binding
HVZ24_18895	COG3116	cell division
HVZ24_18905	COG2001	Belongs to the MraZ family
HVZ24_18910	COG1609	Transcriptional regulator
HVZ24_18920	COG0440	acetolactate synthase activity
HVZ24_18925	COG0028	Belongs to the TPP enzyme family
HVZ24_18935	COG0583	DNA-binding transcription factor activity
HVZ24_18950	COG0473	3-isopropylmalate dehydrogenase activity
HVZ24_18965	COG2814	Major facilitator Superfamily
HVZ24_18975	COG4533	DNA binding
HVZ24_18980	COG4143	(ABC) transporter
HVZ24_18985	COG1178	ABC-type Fe3 transport system permease component
HVZ24_18990	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HVZ24_18995	COG0586	Pfam SNARE associated Golgi protein
HVZ24_19000	COG4977	sequence-specific DNA binding
HVZ24_19005	COG1069	ribulokinase activity
HVZ24_19010	COG2160	L-arabinose isomerase activity
HVZ24_19015	COG0235	Class ii aldolase
HVZ24_19020	COG0417	DNA replication proofreading
HVZ24_19030	COG0564	pseudouridine synthase activity
HVZ24_19050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HVZ24_19055	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HVZ24_19060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVZ24_19085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HVZ24_19100	COG2271	Major facilitator Superfamily
HVZ24_19105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVZ24_19110	COG0644	oxidoreductase
HVZ24_19160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HVZ24_19165	COG0505	Belongs to the CarA family
HVZ24_19185	COG1047	Peptidyl-prolyl cis-trans
HVZ24_19200	COG0196	riboflavin kinase activity
HVZ24_19230	COG0583	DNA-binding transcription factor activity
HVZ24_19245	COG3385	transposase activity
HVZ24_19265	COG4735	regulation of single-species biofilm formation
HVZ24_19270	COG1584	GPR1 FUN34 yaaH family protein
HVZ24_19275	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVZ24_19285	COG1115	amino acid carrier protein
HVZ24_19300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HVZ24_19310	COG0527	aspartate kinase activity
HVZ24_19310	COG0460	homoserine dehydrogenase
HVZ24_19320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HVZ24_19330	COG0745	RESPONSE REGULATOR receiver
HVZ24_19335	COG4452	Inner membrane protein CreD
HVZ24_19340	COG2205	protein histidine kinase activity
HVZ24_19345	COG0745	RESPONSE REGULATOR receiver
HVZ24_19350	COG3045	CreA protein
HVZ24_19355	COG2207	Transcriptional regulator
HVZ24_19355	COG3708	Transcriptional regulator
HVZ24_19375	COG0741	lytic transglycosylase activity
HVZ24_19380	COG0488	(ABC) transporter
HVZ24_19385	COG3172	ATPase kinase involved in NAD metabolism
HVZ24_19385	COG1056	cytidyltransferase-related domain
HVZ24_19390	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HVZ24_19395	COG0560	Phosphoserine phosphatase
HVZ24_19400	COG3726	membrane protein affecting hemolysin expression
HVZ24_19435	COG1328	CTP reductase activity
HVZ24_19440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVZ24_19445	COG0084	hydrolase, TatD family'
HVZ24_19450	COG4667	esterase of the alpha-beta hydrolase superfamily
HVZ24_19460	COG2823	Periplasmic or secreted lipoprotein
HVZ24_19470	COG1011	Hydrolase
HVZ24_19475	COG0456	acetyltransferase
HVZ24_19480	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HVZ24_19510	COG4114	ferric iron reductase
HVZ24_19515	COG2197	response regulator
HVZ24_19520	COG2197	response regulator
HVZ24_19525	COG2966	Psort location CytoplasmicMembrane, score
HVZ24_19540	COG1484	DNA-dependent DNA replication
HVZ24_19555	COG1063	alcohol dehydrogenase
HVZ24_19560	COG1802	Transcriptional regulator
HVZ24_19565	COG2271	Major facilitator Superfamily
HVZ24_19570	COG0840	transmembrane signaling receptor activity
HVZ24_19575	COG1846	Transcriptional regulator
HVZ24_19580	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVZ24_19585	COG1012	belongs to the aldehyde dehydrogenase family
HVZ24_19590	COG3384	dioxygenase
HVZ24_19600	COG3971	2-oxopent-4-enoate hydratase activity
HVZ24_19620	COG2368	4-hydroxyphenylacetate
HVZ24_19625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVZ24_19630	COG1966	Carbon starvation protein
HVZ24_19635	COG2879	small protein
HVZ24_19640	COG0523	cobalamin synthesis protein
HVZ24_19650	COG5457	Domain of unknown function (DUF1127)
HVZ24_19655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HVZ24_19665	COG2814	Major facilitator Superfamily
HVZ24_19670	COG2733	membrane
HVZ24_19675	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HVZ24_19680	COG1924	4 iron, 4 sulfur cluster binding
HVZ24_19695	COG0477	Major facilitator Superfamily
HVZ24_19705	COG3366	ferrous iron transmembrane transporter activity
HVZ24_19710	COG0700	Nucleoside recognition
HVZ24_19715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVZ24_19720	COG0583	DNA-binding transcription factor activity
HVZ24_19740	COG2186	Transcriptional regulator
HVZ24_19745	COG0246	Mannitol dehydrogenase
HVZ24_19755	COG2610	gluconate transmembrane transporter activity
HVZ24_19760	COG3539	Fimbrial protein
HVZ24_19765	COG3539	Fimbrial protein
HVZ24_19770	COG3539	Fimbrial protein
HVZ24_19775	COG3188	usher protein
HVZ24_19780	COG3121	Chaperone
HVZ24_19785	COG3539	Fimbrial protein
HVZ24_19790	COG3539	Fimbrial protein
HVZ24_19795	COG4974	Belongs to the 'phage' integrase family
HVZ24_19800	COG0582	viral genome integration into host DNA
HVZ24_19805	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HVZ24_19810	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HVZ24_19830	COG0210	DNA helicase
HVZ24_19835	COG1205	dead DEAH box helicase
HVZ24_19835	COG1111	helicase
HVZ24_19865	COG0582	viral genome integration into host DNA
HVZ24_19875	COG1064	alcohol dehydrogenase
HVZ24_19880	COG3265	gluconokinase activity
HVZ24_19885	COG1063	alcohol dehydrogenase
HVZ24_19890	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_19895	COG2610	gluconate transmembrane transporter activity
HVZ24_19900	COG1609	Transcriptional regulator
HVZ24_19905	COG0433	COG0433 Predicted ATPase
HVZ24_19910	COG0795	lipopolysaccharide-transporting ATPase activity
HVZ24_19915	COG0795	lipopolysaccharide-transporting ATPase activity
HVZ24_19925	COG2927	DNA polymerase III (CHI subunit)
HVZ24_19940	COG0456	acetyltransferase
HVZ24_19945	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HVZ24_19960	COG2731	YhcH YjgK YiaL family protein
HVZ24_19965	COG1309	transcriptional regulator
HVZ24_19970	COG1028	Short-chain dehydrogenase reductase Sdr
HVZ24_19975	COG0251	oxidation-reduction process
HVZ24_19995	COG0251	oxidation-reduction process
HVZ24_20000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HVZ24_20010	COG1609	Transcriptional regulator
HVZ24_20015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_20015	COG1263	PTS System
HVZ24_20020	COG0366	Alpha amylase catalytic
HVZ24_20025	COG1328	CTP reductase activity
HVZ24_20030	COG0602	queuosine metabolic process
HVZ24_20035	COG3783	Cytochrome b(562)
HVZ24_20040	COG0312	modulator of DNA gyrase
HVZ24_20050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HVZ24_20060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_20065	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_20070	COG1129	ABC transporter
HVZ24_20075	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_20080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HVZ24_20085	COG2105	PFAM AIG2 family protein
HVZ24_20090	COG2911	Protein conserved in bacteria
HVZ24_20095	COG0729	surface antigen
HVZ24_20105	COG1253	flavin adenine dinucleotide binding
HVZ24_20115	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HVZ24_20120	COG1218	3'(2'),5'-bisphosphate nucleotidase
HVZ24_20125	COG0737	Belongs to the 5'-nucleotidase family
HVZ24_20130	COG1733	regulation of RNA biosynthetic process
HVZ24_20135	COG0702	epimerase
HVZ24_20140	COG0697	spore germination
HVZ24_20150	COG1113	amino acid transport
HVZ24_20155	COG0545	Peptidyl-prolyl cis-trans isomerase
HVZ24_20160	COG3061	Opacity-associated protein A
HVZ24_20165	COG1309	transcriptional regulator
HVZ24_20180	COG1024	Enoyl-CoA hydratase
HVZ24_20185	COG4670	ketone body catabolic process
HVZ24_20190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HVZ24_20195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVZ24_20205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVZ24_20215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HVZ24_20255	COG3414	Phosphotransferase system galactitol-specific IIB component
HVZ24_20260	COG3037	sugar-specific permease SgaT UlaA
HVZ24_20275	COG1073	alpha beta
HVZ24_20280	COG3650	response to hydrogen peroxide
HVZ24_20290	COG1960	acyl-CoA dehydrogenase activity
HVZ24_20295	COG0754	glutathionylspermidine amidase activity
HVZ24_20300	COG5463	Belongs to the UPF0441 family
HVZ24_20305	COG3766	membrane
HVZ24_20315	COG1842	Phage shock protein A
HVZ24_20320	COG3789	protein conserved in bacteria
HVZ24_20325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVZ24_20330	COG0557	exoribonuclease II activity
HVZ24_20345	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HVZ24_20350	COG0330	HflC and HflK could
HVZ24_20355	COG0330	HflC and HflK could
HVZ24_20360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HVZ24_20380	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVZ24_20385	COG0802	atpase or kinase
HVZ24_20390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HVZ24_20390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HVZ24_20395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HVZ24_20435	COG1511	domain protein
HVZ24_20435	COG3264	Mechanosensitive ion channel
HVZ24_20450	COG0531	amino acid
HVZ24_20460	COG1053	succinate dehydrogenase
HVZ24_20465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVZ24_20480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVZ24_20485	COG3040	lipid binding
HVZ24_20490	COG2076	Multidrug Resistance protein
HVZ24_20495	COG5510	response to toxic substance
HVZ24_20500	COG5510	response to toxic substance
HVZ24_20510	COG1509	lysine 2,3-aminomutase activity
HVZ24_20535	COG0531	amino acid
HVZ24_20540	COG3030	protein affecting phage T7 exclusion by the F plasmid
HVZ24_20545	COG1027	Aspartate ammonia-lyase
HVZ24_20550	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVZ24_20560	COG4232	protein-disulfide reductase activity
HVZ24_20565	COG1309	transcriptional regulator
HVZ24_20575	COG3710	Transcriptional regulator
HVZ24_20580	COG0531	amino acid
HVZ24_20585	COG1982	Orn Lys Arg decarboxylase major
HVZ24_20590	COG3104	oligopeptide transport
HVZ24_20595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVZ24_20610	COG2388	GCN5-related N-acetyl-transferase
HVZ24_20615	COG3592	Divergent 4Fe-4S mono-cluster
HVZ24_20620	COG3290	protein histidine kinase activity
HVZ24_20625	COG4565	transcriptional regulatory protein
HVZ24_20630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVZ24_20635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_20635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVZ24_20640	COG3647	Membrane
HVZ24_20645	COG2211	Major facilitator Superfamily
HVZ24_20650	COG1486	melibiose metabolic process
HVZ24_20655	COG2169	Transcriptional regulator
HVZ24_20660	COG1982	Orn Lys Arg decarboxylase major
HVZ24_20665	COG2207	Transcriptional regulator
HVZ24_20670	COG0531	amino acid
HVZ24_20675	COG2194	sulfuric ester hydrolase activity
HVZ24_20680	COG0745	RESPONSE REGULATOR receiver
HVZ24_20685	COG0642	Histidine kinase
HVZ24_20695	COG0477	Major facilitator Superfamily
HVZ24_20705	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HVZ24_20710	COG2824	Alkylphosphonate utilization operon protein PhnA
HVZ24_20715	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HVZ24_20720	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HVZ24_20725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HVZ24_20735	COG2188	Transcriptional regulator
HVZ24_20740	COG3624	Phosphonate C-P lyase system protein PhnG
HVZ24_20745	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HVZ24_20750	COG3626	phosphonate metabolism
HVZ24_20755	COG3627	carbon phosphorus lyase activity
HVZ24_20760	COG4107	phosphonate C-P lyase system protein PhnK
HVZ24_20765	COG4778	phosphonate C-P lyase system protein PhnL
HVZ24_20770	COG3454	Phosphonate metabolism
HVZ24_20775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HVZ24_20780	COG0456	acetyltransferase
HVZ24_20785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HVZ24_20795	COG0698	ribose 5-phosphate isomerase
HVZ24_20800	COG1737	Transcriptional regulator
HVZ24_20805	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_20810	COG1129	ABC transporter
HVZ24_20815	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_20820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HVZ24_20825	COG1940	carbohydrate kinase activity
HVZ24_20830	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HVZ24_20840	COG1566	PFAM secretion protein HlyD family protein
HVZ24_20845	COG1289	transmembrane transporter activity
HVZ24_20850	COG1538	Outer membrane efflux protein
HVZ24_20860	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVZ24_20865	COG1301	dicarboxylic acid transport
HVZ24_20870	COG4235	cytochrome complex assembly
HVZ24_20875	COG3088	subunit of a heme lyase
HVZ24_20880	COG1138	Cytochrome C-type biogenesis protein
HVZ24_20885	COG3301	Polysulphide reductase, NrfD
HVZ24_20890	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_20895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HVZ24_20905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVZ24_20910	COG3162	membrane
HVZ24_20920	COG1357	PFAM Pentapeptide repeats (8 copies)
HVZ24_20925	COG0025	NhaP-type Na H and K H
HVZ24_20930	COG2252	PERMEase
HVZ24_20935	COG0789	Transcriptional regulator
HVZ24_20940	COG2207	Transcriptional regulator
HVZ24_20945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HVZ24_20955	COG0629	single-stranded DNA binding
HVZ24_20960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HVZ24_20965	COG2315	Protein conserved in bacteria
HVZ24_20970	COG0432	Pfam Uncharacterised protein family UPF0047
HVZ24_20975	COG3700	Belongs to the class B bacterial acid phosphatase family
HVZ24_20985	COG1448	Aminotransferase
HVZ24_20990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVZ24_20995	COG0305	Participates in initiation and elongation during chromosome replication
HVZ24_21000	COG0604	alcohol dehydrogenase
HVZ24_21010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVZ24_21020	COG0735	belongs to the Fur family
HVZ24_21025	COG3237	CsbD-like
HVZ24_21030	COG0534	Mate efflux family protein
HVZ24_21040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HVZ24_21075	COG3842	ATPase activity
HVZ24_21080	COG2182	Extracellular solute-binding protein
HVZ24_21085	COG1175	transmembrane transport
HVZ24_21090	COG3833	ABC-type maltose transport systems, permease component
HVZ24_21095	COG0477	Major facilitator Superfamily
HVZ24_21095	COG2814	Major facilitator Superfamily
HVZ24_21115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVZ24_21140	COG0527	aspartate kinase activity
HVZ24_21150	COG1187	pseudouridine synthase activity
HVZ24_21160	COG1283	sodium-dependent phosphate transmembrane transporter activity
HVZ24_21165	COG1410	methionine synthase
HVZ24_21165	COG0646	methionine synthase
HVZ24_21170	COG1414	Transcriptional regulator
HVZ24_21185	COG2224	Isocitrate lyase
HVZ24_21190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HVZ24_21200	COG0456	acetyltransferase
HVZ24_21235	COG0151	Belongs to the GarS family
HVZ24_21240	COG2204	response regulator
HVZ24_21245	COG4191	Histidine kinase
HVZ24_21250	COG3678	ATP-independent chaperone mediated protein folding
HVZ24_21265	COG3068	Protein conserved in bacteria
HVZ24_21300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVZ24_21305	COG2104	thiamine diphosphate biosynthetic process
HVZ24_21315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HVZ24_21355	COG0250	Participates in transcription elongation, termination and antitermination
HVZ24_21360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVZ24_21395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HVZ24_21395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HVZ24_21400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HVZ24_21430	COG4206	TonB-dependent receptor
HVZ24_21445	COG1309	transcriptional regulator
HVZ24_21455	COG0583	DNA-binding transcription factor activity
HVZ24_21470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HVZ24_21485	COG2194	sulfuric ester hydrolase activity
HVZ24_21490	COG2207	Transcriptional regulator
HVZ24_21495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_21500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVZ24_21505	COG1882	Formate acetyltransferase
HVZ24_21510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_21515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_21520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVZ24_21520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_21520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_21525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVZ24_21530	COG0371	Dehydrogenase
HVZ24_21535	COG3738	Protein conserved in bacteria
HVZ24_21540	COG0697	spore germination
HVZ24_21550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HVZ24_21555	COG0527	aspartate kinase activity
HVZ24_21555	COG0460	homoserine dehydrogenase
HVZ24_21560	COG0626	cystathionine gamma-synthase activity
HVZ24_21570	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HVZ24_21580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HVZ24_21585	COG1609	Transcriptional regulator
HVZ24_21590	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVZ24_21605	COG1575	Belongs to the MenA family. Type 1 subfamily
HVZ24_21620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HVZ24_21630	COG1494	fructose-1,6-bisphosphatase
HVZ24_21635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVZ24_21640	COG0589	response to stress
HVZ24_21645	COG3691	Protein conserved in bacteria
HVZ24_21650	COG3152	Membrane
HVZ24_21670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HVZ24_21685	COG3678	ATP-independent chaperone mediated protein folding
HVZ24_21690	COG0745	RESPONSE REGULATOR receiver
HVZ24_21695	COG2205	protein histidine kinase activity
HVZ24_21700	COG2258	MOSC domain
HVZ24_21710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVZ24_21750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_21755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_21755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVZ24_21760	COG1363	Peptidase, m42
HVZ24_21765	COG3711	transcriptional antiterminator
HVZ24_21765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVZ24_21785	COG0437	4 iron, 4 sulfur cluster binding
HVZ24_21790	COG2864	formate dehydrogenase
HVZ24_21800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVZ24_21805	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVZ24_21810	COG0456	acetyltransferase
HVZ24_21825	COG1011	Hydrolase
HVZ24_21830	COG1349	DNA-binding transcription factor activity
HVZ24_21835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_21845	COG3684	Belongs to the aldolase LacD family
HVZ24_21850	COG2942	2-epimerase
HVZ24_21855	COG2017	converts alpha-aldose to the beta-anomer
HVZ24_21860	COG1501	Belongs to the glycosyl hydrolase 31 family
HVZ24_21865	COG2211	Major facilitator Superfamily
HVZ24_21870	COG2211	Major facilitator Superfamily
HVZ24_21875	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HVZ24_21880	COG2271	Major facilitator Superfamily
HVZ24_21885	COG1082	Xylose isomerase domain protein TIM barrel
HVZ24_21890	COG2188	Transcriptional regulator
HVZ24_21900	COG0174	glutamine synthetase
HVZ24_21905	COG3852	Histidine kinase
HVZ24_21910	COG2204	response regulator
HVZ24_21920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVZ24_21935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVZ24_21935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVZ24_21940	COG0204	Acyl-transferase
HVZ24_21945	COG5339	Protein conserved in bacteria
HVZ24_21950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVZ24_21955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HVZ24_21960	COG3084	Protein conserved in bacteria
HVZ24_21965	COG0746	molybdenum cofactor guanylyltransferase activity
HVZ24_21970	COG1763	Mo-molybdopterin cofactor biosynthetic process
HVZ24_22000	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HVZ24_22005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVZ24_22010	COG1739	Uncharacterized protein family UPF0029
HVZ24_22025	COG0183	Belongs to the thiolase family
HVZ24_22030	COG0543	2 iron, 2 sulfur cluster binding
HVZ24_22035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HVZ24_22040	COG0250	Participates in transcription elongation, termination and antitermination
HVZ24_22045	COG0084	hydrolase, TatD family'
HVZ24_22050	COG0805	protein transport
HVZ24_22055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVZ24_22060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVZ24_22070	COG3165	ubiquinone biosynthetic process from chorismate
HVZ24_22080	COG1322	Protein conserved in bacteria
HVZ24_22085	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HVZ24_22090	COG0412	Dienelactone hydrolase
HVZ24_22100	COG0583	DNA-binding transcription factor activity
HVZ24_22105	COG0697	spore germination
HVZ24_22110	COG0561	phosphatase activity
HVZ24_22115	COG2267	carboxylic ester hydrolase activity
HVZ24_22120	COG1280	lysine exporter protein (LysE YggA)
HVZ24_22125	COG1280	lysine exporter protein (LysE YggA)
HVZ24_22130	COG0514	ATP-dependent DNA helicase (RecQ)
HVZ24_22135	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HVZ24_22140	COG2050	protein possibly involved in aromatic compounds catabolism
HVZ24_22145	COG2962	Rard protein
HVZ24_22160	COG0598	Magnesium transport protein CorA
HVZ24_22165	COG3698	Phosphodiester glycosidase
HVZ24_22170	COG0210	DNA helicase
HVZ24_22175	COG1011	Hydrolase
HVZ24_22185	COG3159	Protein conserved in bacteria
HVZ24_22195	COG5567	small periplasmic lipoprotein
HVZ24_22205	COG3072	Adenylate cyclase
HVZ24_22215	COG1587	Uroporphyrinogen-III synthase
HVZ24_22220	COG2959	enzyme of heme biosynthesis
HVZ24_22225	COG3071	HemY protein
HVZ24_22230	COG3119	arylsulfatase activity
HVZ24_22235	COG0641	radical SAM
HVZ24_22260	COG1113	amino acid transport
HVZ24_22280	COG2244	polysaccharide biosynthetic process
HVZ24_22285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HVZ24_22290	COG0456	acetyltransferase
HVZ24_22295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HVZ24_22300	COG1088	dTDP-glucose 4,6-dehydratase activity
HVZ24_22305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HVZ24_22310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HVZ24_22315	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVZ24_22320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HVZ24_22325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HVZ24_22335	COG3118	belongs to the thioredoxin family
HVZ24_22350	COG0210	DNA helicase
HVZ24_22360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVZ24_22370	COG0583	DNA-binding transcription factor activity
HVZ24_22375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVZ24_22385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVZ24_22390	COG3978	acetolactate synthase activity
HVZ24_22410	COG0606	chelatase, subunit chli
HVZ24_22415	COG3085	chromosome segregation
HVZ24_22455	COG2186	Transcriptional regulator
HVZ24_22460	COG0477	Major facilitator Superfamily
HVZ24_22465	COG1609	Transcriptional regulator
HVZ24_22470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVZ24_22475	COG1879	ABC-type sugar transport system periplasmic component
HVZ24_22480	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVZ24_22485	COG1129	ABC transporter
HVZ24_22515	COG1522	sequence-specific DNA binding
HVZ24_22520	COG0716	FMN binding
HVZ24_22535	COG3312	ion transport
HVZ24_22585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HVZ24_22590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HVZ24_22595	COG0573	inorganic phosphate transmembrane transporter activity
HVZ24_22600	COG0581	inorganic phosphate transmembrane transporter activity
HVZ24_22605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HVZ24_22610	COG0704	Plays a role in the regulation of phosphate uptake
HVZ24_22615	COG3711	transcriptional antiterminator
HVZ24_22620	COG2190	(PTS) system
HVZ24_22620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVZ24_22620	COG1263	PTS System
HVZ24_22625	COG2723	6-phospho-beta-galactosidase activity
HVZ24_22635	COG2382	esterase
HVZ24_22640	COG0363	glucosamine-6-phosphate deaminase activity
HVZ24_22645	COG3196	Protein conserved in bacteria
HVZ24_22655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVZ24_22660	COG2252	PERMEase
HVZ24_22665	COG0431	NADPH-dependent FMN reductase
HVZ24_22670	COG2091	lysine biosynthetic process via aminoadipic acid
HVZ24_22685	COG0814	amino acid