locus-tag class description HHJ45_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HHJ45_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ45_00030 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HHJ45_00035 ENOG410667J hydrolase HHJ45_00040 ENOG410657R replicase EC 2.7 HHJ45_00045 ENOG4105EMF GntR family transcriptional regulator HHJ45_00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ45_00055 ENOG4108RTU Aldolase HHJ45_00065 ENOG4105DJB Major Facilitator Superfamily HHJ45_00075 ENOG4105D99 atp gtp-binding protein HHJ45_00080 ENOG4105R2A (LipO)protein HHJ45_00100 ENOG4105FDP GntR family transcriptional regulator HHJ45_00105 ENOG4105CI1 PTS System HHJ45_00120 ENOG4108AHD Transcriptional regulator HHJ45_00125 ENOG4107RUZ Sss sodium solute transporter superfamily HHJ45_00130 ENOG4105CBG Sulfatase HHJ45_00135 ENOG4106DRA Inner membrane protein YidI HHJ45_00140 ENOG4105VG5 Membrane HHJ45_00145 ENOG4105JP4 Inner membrane protein yidG HHJ45_00150 ENOG4105J13 transcriptional regulator HHJ45_00155 ENOG4105E5M Multidrug resistance protein D HHJ45_00170 ENOG4105C7K acetolactate synthase HHJ45_00175 ENOG4105M71 acetolactate synthase 1 regulatory subunit HHJ45_00180 ENOG4108KX4 response regulator HHJ45_00185 ENOG4105BZU Histidine kinase HHJ45_00190 ENOG4105CXY transporter HHJ45_00195 ENOG4105CXY transporter HHJ45_00205 ENOG4105C7N Xanthine uracil vitamin C permease HHJ45_00210 ENOG4108SAJ Protein of unknown function (DUF1198) HHJ45_00220 ENOG4105T8A Uncharacterized protein YicS HHJ45_00225 ENOG4105D01 (LipO)protein HHJ45_00230 ENOG4108UZ3 Transporter HHJ45_00235 ENOG4105S8Q sugar efflux transporter HHJ45_00250 ENOG4105CT4 transporter HHJ45_00255 ENOG4105CJQ hydrolase, family 31 HHJ45_00260 ENOG4105JV1 AsmA family HHJ45_00265 ENOG4105C2W permease HHJ45_00270 ENOG4105D6U Sodium Glutamate Symporter HHJ45_00280 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ45_00285 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HHJ45_00290 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ45_00300 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HHJ45_00310 ENOG4105EN6 Membrane HHJ45_00315 ENOG4105F5P DNA-damage-inducible protein d HHJ45_00320 ENOG4105F5P DNA-damage-inducible protein d HHJ45_00410 ENOG4105DSJ YicC domain protein HHJ45_00430 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HHJ45_00435 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HHJ45_00445 ENOG4105KDC 50s ribosomal protein l28 HHJ45_00465 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HHJ45_00470 ENOG4105DKP glycosyl transferase, family 9 HHJ45_00475 ENOG4107RJ7 Glycosyl transferase (Group 1 HHJ45_00480 ENOG4107543 (lipo)polysaccharide HHJ45_00510 ENOG41068PG O-Antigen polymerase HHJ45_00515 ENOG4105D16 lipopolysaccharide heptosyltransferase i HHJ45_00520 ENOG4105XA0 heptosyltransferase ii HHJ45_00530 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ45_00540 ENOG4105K64 Glycosyl transferase, family 2 HHJ45_00545 ENOG4105PXI polysaccharide deacetylase HHJ45_00550 ENOG41063SB peptidase HHJ45_00560 ENOG4107YZP Rhodanese domain protein HHJ45_00565 ENOG4105VW4 glutaredoxin 3 HHJ45_00580 ENOG4105D7W serine acetyltransferase HHJ45_00585 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HHJ45_00595 ENOG41073TP transcriptional regulator HHJ45_00600 ENOG4105DAA L-lactate HHJ45_00605 ENOG4105EUR Domain-Containing protein HHJ45_00615 ENOG4108YYI Protein of unknown function (DUF2810) HHJ45_00625 ENOG4105E61 Mannitol repressor protein HHJ45_00635 ENOG4105CTS PTS system mannitol-specific HHJ45_00640 ENOG4105FP6 Protein of unknown function (DUF3302) HHJ45_00645 ENOG4105EFX secretion protein, HlyD family HHJ45_00675 ENOG4105CNA YD repeat protein HHJ45_00680 ENOG4108U78 Glutathione S-transferase HHJ45_00690 ENOG4105EM7 Selenocysteine-specific translation elongation factor HHJ45_00695 ENOG4105C0A alcohol dehydrogenase HHJ45_00700 ENOG4105C26 Dehydrogenase HHJ45_00710 ENOG4105KK7 inner membrane protein YiaW HHJ45_00715 ENOG4105EFX secretion protein, HlyD family HHJ45_00720 ENOG4108Q2M Transcriptional regulator HHJ45_00725 ENOG4105GNX MltA-interacting MipA family protein HHJ45_00735 ENOG4105CT4 transporter HHJ45_00745 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ45_00750 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ45_00755 ENOG4105H6Q decarboxylase HHJ45_00760 ENOG4105CMG Carbohydrate kinase HHJ45_00765 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ45_00770 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ45_00775 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HHJ45_00780 ENOG4108R66 Conserved Protein HHJ45_00790 ENOG4105J4Q Transcriptional regulator HHJ45_00795 ENOG4108XIB electron transport protein ysaA HHJ45_00800 ENOG4105JKW Valine--pyruvate aminotransferase HHJ45_00805 ENOG4107T9C Alpha amylase catalytic region HHJ45_00810 ENOG4108UR8 BAX protein HHJ45_00815 ENOG4105T16 Transcriptional regulator (AraC family) HHJ45_00820 ENOG4108HWW ABC transporter HHJ45_00825 ENOG4105C2J ABC transporter HHJ45_00830 ENOG4105DFW ABC transporter HHJ45_00840 ENOG4105CMG Carbohydrate kinase HHJ45_00845 ENOG410688U Inner membrane protein yiaB HHJ45_00850 ENOG4108Z12 YiaAB two helix domain-containing protein HHJ45_00855 ENOG4105MEV Acyl-transferase HHJ45_00875 ENOG41060TC Hok gef cell toxic protein HHJ45_00885 ENOG4105MVF Transcriptional regulator HHJ45_00890 ENOG4106JH6 (LipO)protein HHJ45_00900 ENOG4108ZG0 Ompa motb domain protein HHJ45_00905 ENOG4107QY8 reductase HHJ45_00910 ENOG4105HNP -acetyltransferase HHJ45_00915 ENOG4108R3E Dna-3-methyladenine glycosylase i HHJ45_00920 ENOG4105EAX Putative lipase HHJ45_00925 ENOG4105FCD Major Facilitator HHJ45_00930 ENOG4105DIJ Phosphoethanolamine transferase HHJ45_00955 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ45_00960 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ45_00965 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ45_00970 ENOG4105C3U ABC transporter HHJ45_00975 ENOG4108JQ7 (ABC) transporter HHJ45_00980 ENOG4105C44 Serine transporter HHJ45_00995 ENOG4105WQA Cellulose biosynthesis protein BcsF HHJ45_01000 ENOG4105U74 cellulose biosynthesis protein BcsE HHJ45_01005 ENOG410661M cytoplasmic protein HHJ45_01015 ENOG4107QZ7 Cellulose synthase catalytic subunit HHJ45_01020 ENOG4107EEX Cellulose synthase regulator protein HHJ45_01025 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HHJ45_01030 ENOG4105EJG cellulose synthase HHJ45_01035 ENOG4105BZU Histidine kinase HHJ45_01045 ENOG4105CS0 peptidase HHJ45_01055 ENOG4105CMB EAL domain-containing protein HHJ45_01060 ENOG41066T0 asmA family HHJ45_01065 ENOG4105CSH Transporter HHJ45_01070 ENOG4107H3J ribonuclease HHJ45_01075 ENOG4105CBN LysR family transcriptional regulator HHJ45_01080 ENOG4106S2D Transcriptional regulator HHJ45_01090 ENOG4105CA0 peroxidase HHJ45_01100 ENOG4108NKV transcriptional regulator HHJ45_01110 ENOG4105BZS acriflavin resistance protein HHJ45_01115 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ45_01125 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HHJ45_01130 ENOG4108YK4 Acid-resistance membrane protein HHJ45_01135 ENOG41060V2 Acid-resistance protein HHJ45_01140 ENOG4105XXV Acid-resistance protein HHJ45_01145 ENOG4105KT7 mgtC SapB transporter HHJ45_01155 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ45_01175 ENOG4105K89 arsenate reductase HHJ45_01180 ENOG4107R5R arsenical pump membrane protein HHJ45_01185 ENOG4105KBH arsR family transcriptional regulator HHJ45_01195 ENOG4105DC8 reductase HHJ45_01200 ENOG4105D6S protein involved in catabolism of external DNA HHJ45_01205 ENOG4105DGW oligopeptidase A HHJ45_01215 ENOG4105DUX Transporter HHJ45_01230 ENOG4105CJ3 phosphate transporter HHJ45_01235 ENOG4105CBX hi0933 family HHJ45_01240 ENOG4107UNS conserved inner membrane protein HHJ45_01270 ENOG4105D0S secretion protein (HlyD HHJ45_01275 ENOG4105CJ1 ABC, transporter HHJ45_01280 ENOG4105CMI transporter HHJ45_01305 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ45_01310 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ45_01315 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ45_01320 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HHJ45_01325 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HHJ45_01330 ENOG4105DSF transport protein HHJ45_01335 ENOG4105F9N Major Facilitator Superfamily HHJ45_01340 ENOG4108W1V Lipoprotein HHJ45_01345 ENOG4105EX9 Membrane HHJ45_01360 ENOG4107FS9 Membrane HHJ45_01370 ENOG4105MG3 Membrane HHJ45_01375 ENOG4106H78 methyltransferase HHJ45_01380 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HHJ45_01385 ENOG4105CAK Cell division ATP-binding protein ftsE HHJ45_01390 ENOG4105CRP Part of the ABC transporter FtsEX involved in HHJ45_01395 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ45_01400 ENOG4105CP9 extracellular ligand-binding receptor HHJ45_01415 ENOG4105U59 -acetyltransferase HHJ45_01420 ENOG4105CP9 extracellular ligand-binding receptor HHJ45_01425 ENOG4105C32 Amino acid ABC transporter (Permease) HHJ45_01430 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HHJ45_01435 ENOG4105C0Z ABC transporter HHJ45_01440 ENOG4108IV0 ABC, transporter HHJ45_01445 ENOG4105BZ7 extracellular solute-binding protein family 1 HHJ45_01450 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HHJ45_01455 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HHJ45_01460 ENOG4108IJ9 (ABC) transporter HHJ45_01465 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HHJ45_01470 ENOG4105WC8 Conserved Protein HHJ45_01475 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HHJ45_01480 ENOG4106FA4 HHJ45_01495 ENOG4105WCN acetyltransferase HHJ45_01500 ENOG4105D9R oxidoreductase HHJ45_01505 ENOG4105C2I pirin domain protein HHJ45_01510 ENOG4105DIQ Transcriptional regulator HHJ45_01515 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ45_01520 ENOG4105C6Z Gluconate HHJ45_01525 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HHJ45_01530 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ45_01555 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ45_01580 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HHJ45_01595 ENOG4105E98 transcriptional regulator DeoR family HHJ45_01600 ENOG4105CYB regulatoR HHJ45_01605 ENOG4105E0Y RtcB Protein HHJ45_01620 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ45_01625 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HHJ45_01630 ENOG4105C6Z Gluconate HHJ45_01640 ENOG4105MJ2 Competence protein HHJ45_01650 ENOG4105DNE Transposase HHJ45_01660 ENOG4105CE1 Ferrous iron transport protein b HHJ45_01665 ENOG4105XFK Ferrous iron transport protein A HHJ45_01670 ENOG4105BZM domain protein HHJ45_01675 ENOG4108RRZ Transcription elongation factor GreB HHJ45_01685 ENOG4105E0F Histidine kinase HHJ45_01705 ENOG4108MAJ Membrane HHJ45_01715 ENOG4105VEJ Heat shock protein HHJ45_01720 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HHJ45_01725 ENOG4105DQY intracellular growth attenuator HHJ45_01730 ENOG4107RK2 ADP-ribose diphosphatase NudE HHJ45_01735 ENOG4108JQC penicillin-binding protein 1A HHJ45_01740 ENOG4108U1Q Pilus assembly protein HHJ45_01745 ENOG41065NF Fimbrial assembly family protein HHJ45_01750 ENOG4105XPX DNA utilization protein HofO HHJ45_01755 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HHJ45_01760 ENOG4105E4G Type IV pilus HHJ45_01775 ENOG4105EGB membrane protein DamX HHJ45_01780 ENOG4105DFE Dna adenine methylase HHJ45_01785 ENOG4105DJV ribulose-phosphate 3-epimerase HHJ45_01790 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HHJ45_01795 ENOG4105C31 Tryptophanyl-tRNA synthetase HHJ45_01800 ENOG4108M21 HHJ45_01805 ENOG4105RMW regulation of transcription, DNA-dependent HHJ45_01810 ENOG4108626 Racemase HHJ45_01815 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HHJ45_01820 ENOG41080QX K07048 phosphotriesterase-related protein HHJ45_01825 ENOG4105MUZ Protein of unknown function DUF2620 HHJ45_01830 ENOG4106M0N transport system permease protein HHJ45_01835 ENOG4106PKC pyridoxal phosphate binding HHJ45_01840 ENOG4105FDP GntR family transcriptional regulator HHJ45_01845 ENOG4108KPW sugar kinase HHJ45_01850 ENOG4107Y0V Not clear, may be involved in an isomerization step HHJ45_01855 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine HHJ45_01860 ENOG4107QHQ amino acid HHJ45_01865 ENOG4105VYH HHJ45_01875 ENOG4107V9H nitrite transporter HHJ45_01880 ENOG4105WZK nitrite reductase NADPH small subunit HHJ45_01885 ENOG4107QZF nitrite reductase NADPH large subunit HHJ45_01895 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ45_01905 ENOG4105MZU cell filamentation protein HHJ45_01910 ENOG4105DDQ anthranilate synthase HHJ45_01915 ENOG4105C8Y Acetylornithine aminotransferase HHJ45_01920 ENOG410613R integral membrane protein, YccS YhfK family HHJ45_01930 ENOG4108UKZ OsmC family HHJ45_01935 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HHJ45_01945 ENOG4105DNZ Alpha Beta Hydrolase HHJ45_01950 ENOG4105C5H ABC transporter HHJ45_01965 ENOG4105VKU nucleicacid-binding protein HHJ45_01970 ENOG4108YZY peptidylprolyl cis-trans isomerase HHJ45_01980 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ45_01985 ENOG4105WWK YheO domain protein HHJ45_02025 ENOG4105W53 bacterioferritin-associated ferredoxin HHJ45_02030 ENOG4108UQY Iron-storage protein HHJ45_02055 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HHJ45_02100 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HHJ45_02145 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HHJ45_02150 ENOG41067V7 50S ribosomal protein L36 HHJ45_02180 ENOG4105VTS DnaJ-like, subfamily C HHJ45_02185 ENOG4105W1Y Transcriptional regulator HHJ45_02190 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HHJ45_02200 ENOG4105C1A potassium transporter peripheral membrane HHJ45_02220 ENOG4105C79 DNA protecting protein DprA HHJ45_02230 ENOG4108WI1 Dna topoisomerase HHJ45_02245 ENOG4105SG3 Protein of unknown function (DUF1488) HHJ45_02250 ENOG4108Z0R Transferase HHJ45_02290 ENOG4105CDA abc transporter atp-binding protein HHJ45_02295 ENOG4105DRP amino acid AbC transporter HHJ45_02300 ENOG4105EZ7 amino acid ABC transporter HHJ45_02310 ENOG4105XCM membrane LIPOPROTEIN HHJ45_02315 ENOG4105BZS acriflavin resistance protein HHJ45_02320 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ45_02325 ENOG4108XG4 DNA-binding transcriptional regulator HHJ45_02330 ENOG41061ME transport protein HHJ45_02335 ENOG4105CEC DNA methylase N-4 N-6 HHJ45_02345 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ45_02355 ENOG4108IA2 Sodium pantothenate symporter HHJ45_02360 ENOG4105RG0 Membrane HHJ45_02365 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HHJ45_02370 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HHJ45_02375 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ45_02380 ENOG41062P1 Diguanylate cyclase phosphodiesterase HHJ45_02390 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HHJ45_02395 ENOG4105VQ7 Rod shape-determining protein MreD HHJ45_02405 ENOG4105C03 ribonuclease HHJ45_02410 ENOG4105QD6 exported protein HHJ45_02415 ENOG4105D1U peptidase U62 modulator of DNA gyrase HHJ45_02420 ENOG4105CR8 Transcriptional regulator HHJ45_02425 ENOG4105ZQC membrane protein AaeX HHJ45_02440 ENOG4105UNR (Barnase) inhibitor HHJ45_02445 ENOG4105RID UPF0379 protein yhcN HHJ45_02460 ENOG4105C0H protease HHJ45_02465 ENOG4105C0H protease HHJ45_02470 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HHJ45_02475 ENOG4105D6Z AFG1 family ATPase HHJ45_02490 ENOG4107MKT Stringent starvation protein a HHJ45_02495 ENOG4105KB2 stringent starvation protein b HHJ45_02500 ENOG4105CEE C4-dicarboxylate transporter HHJ45_02505 ENOG4108QBF Transcriptional regulator HHJ45_02515 ENOG4105JHE Major Facilitator Superfamily HHJ45_02530 ENOG4108R66 Conserved Protein HHJ45_02535 ENOG4105DFS Conserved Protein HHJ45_02540 ENOG4105BZ8 glutamate synthase HHJ45_02545 ENOG4105CBC glutamate synthase HHJ45_02550 ENOG4105N5T Radical SAM Protein HHJ45_02555 ENOG4105BZU Histidine kinase HHJ45_02560 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HHJ45_02570 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HHJ45_02575 ENOG41080Z8 PHOSPHOCARRIER protein HHJ45_02585 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HHJ45_02590 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HHJ45_02595 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ45_02600 ENOG4108IUZ ABC transporter HHJ45_02605 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HHJ45_02610 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HHJ45_02615 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase HHJ45_02620 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ45_02625 ENOG4105FEU K -dependent Na -Ca exchanger HHJ45_02630 ENOG4105DHJ ABC, transporter HHJ45_02635 ENOG4105CY3 ABC transporter, permease HHJ45_02640 ENOG4107PE3 Mammalian cell entry related domain protein HHJ45_02645 ENOG4105E3I toluene tolerance HHJ45_02650 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HHJ45_02655 ENOG4105VFK BolA family HHJ45_02665 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ45_02670 ENOG4105EAH synthase HHJ45_02685 ENOG4105QYV Membrane HHJ45_02695 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HHJ45_02700 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HHJ45_02705 ENOG4105HBR Rna-binding protein HHJ45_02715 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HHJ45_02720 ENOG4105EEI dihydropteroate synthase HHJ45_02730 ENOG4105NTZ Preprotein translocase subunit SecG HHJ45_02740 ENOG4105DIJ Phosphoethanolamine transferase HHJ45_02760 ENOG4105CHV Transcription elongation factor NusA HHJ45_02800 ENOG4105C1J atp-dependent rna helicase HHJ45_02805 ENOG4105CIC tryptophan-specific transport protein HHJ45_02815 ENOG4105DEN Luciferase family HHJ45_02835 ENOG4108YYD acetyltransferase HHJ45_02850 ENOG4107R7Y intracellular protease Pfpi family HHJ45_02855 ENOG4105K4T epimerase HHJ45_02860 ENOG4107S21 permease HHJ45_02865 ENOG4105W4M Transport-associated protein HHJ45_02885 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ45_02890 ENOG4105I74 Fimbrial protein HHJ45_02895 ENOG4105CW0 outer membrane usher protein HHJ45_02900 ENOG4108VCD Chaperone HHJ45_02905 ENOG4105Q10 Fimbrial-like protein HHJ45_02910 ENOG4106HBN Galactosamine-6-phosphate isomerase HHJ45_02915 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ45_02920 ENOG4105ETZ PTS System HHJ45_02925 ENOG4108UZY PTS System HHJ45_02935 ENOG4105E70 isomerase HHJ45_02940 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ45_02945 ENOG4108YTN IIa component HHJ45_02950 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ45_02960 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HHJ45_02975 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HHJ45_02980 ENOG4105ZEG Suppressor protein HHJ45_02985 ENOG4105CTX dehydratase HHJ45_02990 ENOG4105DJB Major Facilitator Superfamily HHJ45_03000 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ45_03005 ENOG4105BZW Glycerate kinase HHJ45_03035 ENOG410811B TRANSCRIPTIONal HHJ45_03040 ENOG4105C7B Threonine dehydratase HHJ45_03050 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ45_03055 ENOG4105C6N Formate acetyltransferase HHJ45_03060 ENOG4105KME endoribonuclease L-psp HHJ45_03065 ENOG4105EJQ L-serine dehydratase HHJ45_03070 ENOG4105C44 Serine transporter HHJ45_03080 ENOG4106D80 Uncharacterized protein YhaL HHJ45_03085 ENOG4108CNN domain protein HHJ45_03090 ENOG4105CWB LysR family transcriptional Regulator HHJ45_03095 ENOG4105KAF membrAne HHJ45_03100 ENOG4105KAF membrAne HHJ45_03105 ENOG4105CHF Glutathione S-transferase HHJ45_03110 ENOG4108VBZ doxx family HHJ45_03115 ENOG4105YJD HHJ45_03120 ENOG41090KG Inner membrane protein YqjE HHJ45_03125 ENOG4105NE1 Conserved Protein HHJ45_03130 ENOG4105WAY exported protein HHJ45_03135 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HHJ45_03140 ENOG4106W5V Membrane HHJ45_03145 ENOG4107YCY Transcriptional regulator HHJ45_03170 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ45_03180 ENOG4105CTX dehydratase HHJ45_03185 ENOG4105P66 Membrane HHJ45_03190 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HHJ45_03200 ENOG4105DU1 integral membrane protein, terc HHJ45_03205 ENOG4105EE0 oxidoreductase HHJ45_03210 ENOG4108UB4 uncharacterized protein ygjQ HHJ45_03215 ENOG4108VKG metal-dependent hydrolase HHJ45_03230 ENOG4108Z3N Transcriptional regulator HHJ45_03235 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ45_03240 ENOG4107WCA isomerase HHJ45_03245 ENOG4107W6W Conserved Protein HHJ45_03250 ENOG4105E5D amino acid HHJ45_03255 ENOG4105FK9 beta-D-galactosidase beta subunit HHJ45_03260 ENOG4105CNT hydrolase family 2 HHJ45_03265 ENOG4105CQ4 Transcriptional regulator HHJ45_03270 ENOG4108Y51 tRNA-binding protein HHJ45_03280 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HHJ45_03285 ENOG4105NTW Transcriptional regulator HHJ45_03290 ENOG4105Q26 Siderophore-interacting protein HHJ45_03305 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ45_03310 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HHJ45_03325 ENOG4107QPK )-transporter HHJ45_03330 ENOG4107GFK fumarate HHJ45_03335 ENOG4106DSS Tartrate dehydratase subunit alpha HHJ45_03340 ENOG4105EJC lysr family transcriptional regulator HHJ45_03350 ENOG4107ZVW dihydroneopterin aldolase HHJ45_03365 ENOG4106MWK domain protein HHJ45_03370 ENOG4105I7R Adenylate cyclase HHJ45_03395 ENOG4107S78 Band 7 protein HHJ45_03400 ENOG4105PV3 Inner membrane protein yqiJ HHJ45_03420 ENOG4108TTM chaperone HHJ45_03450 ENOG4105W0Z cytoplasmic protein HHJ45_03470 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HHJ45_03475 ENOG4106032 Glutathionylspermidine synthase HHJ45_03485 ENOG4105DFG type I secretion outer membrane protein HHJ45_03490 ENOG41087AY ADP-Ribose pyrophosphatase HHJ45_03495 ENOG4108SX3 cytoplasmic protein HHJ45_03500 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HHJ45_03505 ENOG4105IPS esterase HHJ45_03510 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ45_03530 ENOG4108RVA ribokinase HHJ45_03550 ENOG4105CT4 transporter HHJ45_03555 ENOG4105VRH Antibiotic biosynthesis monooxygenase HHJ45_03560 ENOG4105NF4 modulator of drug activity HHJ45_03565 ENOG4107DEU Inner membrane protein YgiZ HHJ45_03570 ENOG4105DHQ Histidine kinase HHJ45_03575 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ45_03580 ENOG4105H4F exported protein HHJ45_03585 ENOG4105F4I Transcriptional regulator HHJ45_03590 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ45_03595 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HHJ45_03600 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HHJ45_03605 ENOG4105CCT upf0313 protein HHJ45_03615 ENOG4105ZKC Conserved Protein HHJ45_03620 ENOG4105CV8 reductase HHJ45_03625 ENOG4108I6A alcohol dehydrogenase HHJ45_03630 ENOG4105CF7 AraC family transcriptional regulator HHJ45_03635 ENOG4108K81 inner membrane protein YghB HHJ45_03640 ENOG4105C28 cystathionine HHJ45_03645 ENOG4105CWK Biopolymer transport protein, ExbB HHJ45_03650 ENOG4108ZZF transport protein (ExbD) HHJ45_03655 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ45_03665 ENOG4105CPC Aldo Keto reductase HHJ45_03675 ENOG410900S Protein of unknown function (DUF2623) HHJ45_03680 ENOG4105E3S small subunit HHJ45_03685 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ45_03690 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HHJ45_03695 ENOG4105DPX Hydrogenase, large subunit HHJ45_03700 ENOG4108USZ hydrogenase HHJ45_03705 ENOG4108WGS hydrogenase 2-specific chaperone HHJ45_03710 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ45_03715 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HHJ45_03725 ENOG4105CYM Glutathione S-transferase HHJ45_03730 ENOG4106032 Glutathionylspermidine synthase HHJ45_03735 ENOG4105CJ3 phosphate transporter HHJ45_03740 ENOG4108GH0 ATP-binding protein yghT HHJ45_03745 ENOG4108NDC ATP-binding protein yghS HHJ45_03750 ENOG4106FPV ATP-binding protein YghR HHJ45_03755 ENOG4108S55 polysaccharide biosynthesis protein HHJ45_03765 ENOG4108UUE Transcriptional regulator HHJ45_03770 ENOG4108M8S permease YjgP YjgQ family protein HHJ45_03780 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ45_03785 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ45_03795 ENOG4107RCI amp-dependent synthetase and ligase HHJ45_03805 ENOG4108KWP DNA-binding transcriptional regulator GlcC HHJ45_03810 ENOG4105CQB FAD linked oxidase domain protein HHJ45_03815 ENOG4105EU8 FAD linked oxidase domain protein HHJ45_03820 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ45_03825 ENOG4108ZJF Glcg protein HHJ45_03830 ENOG4107QP3 malate synthase g HHJ45_03835 ENOG4105DAA L-lactate HHJ45_03840 ENOG4105F88 accessory colonization factor AcfD HHJ45_03865 ENOG4107QHF type ii secretion system protein e HHJ45_03870 ENOG4105D7Q type ii secretion system HHJ45_03875 ENOG4108VAU general secretion pathway protein G HHJ45_03885 ENOG4105X5Z General secretion pathway protein I HHJ45_03905 ENOG4105U1E general secretion pathway protein M HHJ45_03930 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ45_03940 ENOG4108YGG dna repair protein HHJ45_03945 ENOG4105MFG Antirestriction protein HHJ45_03950 ENOG4106H6R UPF0380 protein HHJ45_03965 ENOG4108KZE transcriptional regulator HHJ45_03970 ENOG4105TS0 gtp-binding protein HHJ45_04060 ENOG4108YXQ IS66 Orf2 family protein HHJ45_04070 ENOG4105F5W AtP-binding protein HHJ45_04075 ENOG4105D70 Integrase catalytic subunit HHJ45_04090 ENOG4105VYH HHJ45_04125 ENOG410810Y Sulfite reductase HHJ45_04130 ENOG4107SHJ sulfite reductase subunit b HHJ45_04135 ENOG4105D5B Sulfite reductase, subunit A HHJ45_04185 ENOG4105GTN ParB Domain Protein Nuclease HHJ45_04205 ENOG4107QRT dEAD DEAH box helicase HHJ45_04250 ENOG4108UQV Membrane HHJ45_04255 ENOG4105CXN decarboxylase HHJ45_04260 ENOG4105EAA nucleoside HHJ45_04275 ENOG4105CEN a g-specific adenine glycosylase HHJ45_04285 ENOG41090ED Protein with unknown function (DUF469) HHJ45_04290 ENOG4105K33 Periplasmic Protein HHJ45_04295 ENOG4105HDK L-asparaginase HHJ45_04300 ENOG4106MH3 alpha helix chain HHJ45_04305 ENOG4105CSA Coproporphyrinogen iii oxidase HHJ45_04310 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ45_04320 ENOG4108VIA integral membrane protein HHJ45_04325 ENOG4105DFA alanine racemase domain protein HHJ45_04330 ENOG4105CZX twitching motility protein HHJ45_04350 ENOG4105D7Z glutathione synthase HHJ45_04355 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HHJ45_04360 ENOG4105RWS endonuclease I HHJ45_04370 ENOG4107QNK )-transporter HHJ45_04390 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HHJ45_04405 ENOG4108K0D peptidase, M48 HHJ45_04410 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ45_04415 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ45_04420 ENOG4105CTS PTS system mannitol-specific HHJ45_04425 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ45_04430 ENOG4108Q8A Fructose-1,6-bisphosphatase HHJ45_04435 ENOG4108R4K DNA-binding, transcriptional regulator HHJ45_04445 ENOG4108JJB ABC transporter HHJ45_04450 ENOG4108JJB ABC transporter HHJ45_04480 ENOG4105D2N Aldolase HHJ45_04485 ENOG4105D64 Mechanosensitive ion channel HHJ45_04490 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HHJ45_04495 ENOG4105MPN Membrane HHJ45_04500 ENOG4105DEQ transcriptional regulator HHJ45_04505 ENOG4105CYC Transferase HHJ45_04510 ENOG4108M7F enoyl-CoA hydratase isomerase HHJ45_04515 ENOG4105DJT lAO AO transport system ATPase HHJ45_04520 ENOG4105D5P Methylmalonyl-coA mutase HHJ45_04540 ENOG4108JQ1 Dehydrogenase HHJ45_04555 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HHJ45_04575 ENOG4107RAQ aminopeptidase HHJ45_04580 ENOG4105D0A hydroxylase HHJ45_04585 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ45_04610 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ45_04615 ENOG4105CS2 ec 3.2.1.21 HHJ45_04625 ENOG4108UT2 hemolysin iii HHJ45_04635 ENOG4105Y75 tpr repeat protein HHJ45_04640 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HHJ45_04645 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HHJ45_04650 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ45_04655 ENOG4105T95 Thiol disulfide interChange protein HHJ45_04660 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HHJ45_04690 ENOG4105C2W permease HHJ45_04695 ENOG4105BZ8 glutamate synthase HHJ45_04700 ENOG4108R8B oxidoreductase Fe-S subunit HHJ45_04705 ENOG4105C7N Xanthine uracil vitamin C permease HHJ45_04710 ENOG4107QUY Guanine deaminase HHJ45_04715 ENOG4105C2W permease HHJ45_04720 ENOG4105C7W Xanthine dehydrogenase HHJ45_04725 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HHJ45_04730 ENOG4107UUR Chlorohydrolase aminohydrolase HHJ45_04735 ENOG4105BZ8 glutamate synthase HHJ45_04740 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HHJ45_04745 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HHJ45_04750 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HHJ45_04755 ENOG4105C5B carbamate kinase HHJ45_04765 ENOG4107S4Y M20 DapE family protein YgeY HHJ45_04770 ENOG4107RCH Diaminopropionate ammonia-lyase HHJ45_04775 ENOG4105IW6 Carbamoyltransferase HHJ45_04780 ENOG4108JUB Transcriptional regulator HHJ45_04785 ENOG4108UTP (2Fe-2S)-binding domain protein HHJ45_04790 ENOG4108HR6 Dehydrogenase HHJ45_04795 ENOG4105C7W Xanthine dehydrogenase HHJ45_04800 ENOG4108K5P (LipO)protein HHJ45_04810 ENOG4108T88 HHJ45_04820 ENOG41075IY surface presentation of antigens protein SpaP HHJ45_04825 ENOG41075IY surface presentation of antigens protein SpaP HHJ45_04835 ENOG4108TN6 type iii secretion HHJ45_04950 ENOG4108MHD transport protein HHJ45_04955 ENOG4105CHU acetyl-coa acetyltransferase HHJ45_04965 ENOG4105CHR reductase HHJ45_04970 ENOG4107QNK )-transporter HHJ45_04980 ENOG4105RQF LysR family Transcriptional regulator HHJ45_04990 ENOG41060NJ transcriptional regulator HHJ45_05000 ENOG4107S74 Lysophospholipid transporter LplT HHJ45_05005 ENOG4105CPC Aldo Keto reductase HHJ45_05010 ENOG4105SUV lipoprotein YgdR HHJ45_05015 ENOG4105EE5 Membrane protein terC HHJ45_05030 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HHJ45_05045 ENOG4105IPU prepilin peptidase dependent protein A HHJ45_05050 ENOG4105JCS prepilin peptidase dependent protein HHJ45_05055 ENOG4105SEN Protein of unknown function (DUF2509) HHJ45_05060 ENOG4105RVB Prepilin peptidase dependent protein c HHJ45_05065 ENOG4105DSY exodeoxyribonuclease V, gamma HHJ45_05070 ENOG4107QXK peptidase HHJ45_05075 ENOG4107QKA exodeoxyribonuclease V beta HHJ45_05080 ENOG4107QYX exodeoxyribonuclease v alpha HHJ45_05085 ENOG4108EKC n-acetylglutamate synthase HHJ45_05090 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ45_05105 ENOG4105CA3 membrane-bound lytic murein transglycosylase HHJ45_05110 ENOG4105CUZ uba thif-type nad fad binding protein HHJ45_05115 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HHJ45_05120 ENOG4105C9B Cysteine desulfurase HHJ45_05125 ENOG4105M5B (LipO)protein HHJ45_05130 ENOG4105ETT transcriptional Regulator, LysR family HHJ45_05135 ENOG4105M08 Membrane HHJ45_05145 ENOG4107EDW L-fucose operon activator HHJ45_05155 ENOG4105CMG Carbohydrate kinase HHJ45_05165 ENOG4105EDR glucose galactose transporter HHJ45_05170 ENOG4107W7X Aldolase HHJ45_05175 ENOG4105C0A alcohol dehydrogenase HHJ45_05185 ENOG4105EJQ L-serine dehydratase HHJ45_05190 ENOG4105C44 Serine transporter HHJ45_05195 ENOG4105EWT decarboxylase family HHJ45_05210 ENOG4105WP7 tRNA pseudouridine synthase C HHJ45_05215 ENOG4105DR9 pseudouridine synthase HHJ45_05220 ENOG4105QDK Flavodoxin HHJ45_05225 ENOG4105DJB Major Facilitator Superfamily HHJ45_05230 ENOG4105EQX glucarate dehydratase HHJ45_05235 ENOG4105EQX glucarate dehydratase HHJ45_05240 ENOG4105BZU Histidine kinase HHJ45_05250 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ45_05255 ENOG4106A2Z transcriptional regulator antitoxin, MazE HHJ45_05260 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ45_05265 ENOG4105DXN mazG family HHJ45_05285 ENOG4105HA9 of methanol dehydrogenase type HHJ45_05295 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HHJ45_05300 ENOG4108CWB sugar kinase ygcE HHJ45_05305 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ45_05325 ENOG4107635 Hok Gef family protein HHJ45_05330 ENOG4105DTT CRISPR-associated helicase, cas3 HHJ45_05335 ENOG4105CYR Crispr-associated protein, cse1 family HHJ45_05345 ENOG41060M0 Crispr-associated protein, cse4 family HHJ45_05350 ENOG4108VWQ crispr-associated protein HHJ45_05360 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HHJ45_05365 ENOG4105PWE CRISPR-associated protein cas2 HHJ45_05370 ENOG4108MXK alkaline phosphatase isozyme conversion HHJ45_05375 ENOG4105C11 sulfate adenylyltransferase), subunit 2 HHJ45_05390 ENOG4105N0Z inner membrane protein ygbE HHJ45_05425 ENOG4108K5P (LipO)protein HHJ45_05430 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ45_05440 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ45_05445 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ45_05450 ENOG4105KZM cytoplasmic protein HHJ45_05455 ENOG4105C6Z Gluconate HHJ45_05460 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ45_05465 ENOG4105FB2 class II Aldolase HHJ45_05470 ENOG4105G63 Type III effector Hrp-dependent HHJ45_05475 ENOG4105ZXK Dehydrogenase HHJ45_05480 ENOG4105MVE transcriptional regulator HHJ45_05485 ENOG4105MEW serine threonine protein phosphatase HHJ45_05590 ENOG4105VXR cytoplasmic protein HHJ45_05595 ENOG4108JUA Transcriptional regulator HHJ45_05600 ENOG4105C45 hydrogenase expression formation protein (HypE) HHJ45_05605 ENOG4105CQS hydrogenase expression formation protein HypD HHJ45_05610 ENOG41083WG hydrogenase assembly chaperone HHJ45_05615 ENOG4107RSS Hydrogenase accessory protein HypB HHJ45_05620 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ45_05625 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HHJ45_05630 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ45_05635 ENOG4107R30 NADH dehydrogenase HHJ45_05640 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ45_05645 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ45_05650 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HHJ45_05655 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ45_05660 ENOG4105I6X formate hydrogenlyase maturation HHJ45_05665 ENOG4108MG9 hydrogenase 3 maturation protease HHJ45_05670 ENOG4105CS2 ec 3.2.1.21 HHJ45_05675 ENOG4105C5Y PTS System HHJ45_05680 ENOG4105DDV Transcriptional regulator (LacI family HHJ45_05685 ENOG4108RC0 Electron transport protein HHJ45_05690 ENOG4105C8H hydrogenase maturation protein Hypf HHJ45_05705 ENOG4108JUA Transcriptional regulator HHJ45_05715 ENOG410804X Transcriptional regulator HHJ45_05720 ENOG4105J92 DNA-binding transcriptional activator GutM HHJ45_05725 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HHJ45_05730 ENOG4105VI0 Pts system, glucitol sorbitol-specific HHJ45_05735 ENOG4105DZY Pts system, glucitol sorbitol-specific HHJ45_05740 ENOG410787A Pts system, glucitol sorbitol-specific HHJ45_05745 ENOG4105CVE Lytic murein transglycosylase HHJ45_05750 ENOG4107TH8 cina domain protein HHJ45_05770 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HHJ45_05800 ENOG4107VXZ Hydrolase HHJ45_05805 ENOG4105W39 Membrane HHJ45_05820 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ45_05825 ENOG4105CW7 secretion protein, HlyD family HHJ45_05830 ENOG4105NTK Transcriptional repressor Mpra HHJ45_05840 ENOG4105ZED uncharacterized protein ygaH HHJ45_05845 ENOG4108UMN azlc family HHJ45_05855 ENOG4105GIJ Glycine betaine HHJ45_05860 ENOG4108HQS Glycine betaine HHJ45_05865 ENOG4108IJ7 Glycine betaine HHJ45_05870 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ45_05875 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ45_05885 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HHJ45_05890 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HHJ45_05895 ENOG4108WMJ Protein of unknown function (DUF2002) HHJ45_05900 ENOG4108RNS Exports L-alanine (By similarity) HHJ45_05905 ENOG4108X73 DNA- binding protein HHJ45_05910 ENOG4108V62 Rhodanese domain protein HHJ45_05915 ENOG41080HT Transcriptional regulator, arsr family HHJ45_05920 ENOG4105VPI YqaE family transport protein HHJ45_05925 ENOG4109066 lysm domain bon superfamily protein HHJ45_05930 ENOG4108PVQ transcriptional regulator HHJ45_05935 ENOG4105C85 amino acid HHJ45_05940 ENOG4108JPW Aminotransferase HHJ45_05945 ENOG4105C26 Dehydrogenase HHJ45_05950 ENOG4105D5U fad dependent oxidoreductase HHJ45_05955 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) HHJ45_06010 ENOG4105DFP Integrase HHJ45_06025 ENOG4108Z1B Cyclase dehydrase HHJ45_06035 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ45_06040 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HHJ45_06055 ENOG4108JU6 CBS domain protein HHJ45_06060 ENOG4106KVJ cytochrome C assembly protein HHJ45_06065 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HHJ45_06090 ENOG41090EK ompa motb domain protein HHJ45_06095 ENOG4108KHX Diguanylate cyclase HHJ45_06100 ENOG4108WS1 HHJ45_06105 ENOG4105QP9 Protein of unknown function (DUF2799) HHJ45_06110 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ45_06115 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HHJ45_06120 ENOG4105CQC Prephenate dehydratase HHJ45_06130 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HHJ45_06135 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HHJ45_06140 ENOG4105C34 Pseudouridine synthase HHJ45_06145 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HHJ45_06150 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ45_06175 ENOG4105CSH Transporter HHJ45_06180 ENOG4105T42 (LipO)protein HHJ45_06185 ENOG4105JIM Phosphatidylserine synthase HHJ45_06190 ENOG4105CD5 CoA-binding domain protein HHJ45_06195 ENOG4106IUH DTW domain containing protein HHJ45_06200 ENOG4105K63 Thioredoxin HHJ45_06205 ENOG4105EIB trna rrna methyltransferase HHJ45_06225 ENOG41090KR LysR family transcriptional Regulator HHJ45_06230 ENOG4105C1J atp-dependent rna helicase HHJ45_06240 ENOG4108IYU L-aspartate oxidase HHJ45_06250 ENOG4105EMN RNA polymerase sigma factor HHJ45_06255 ENOG41069PW sigma-e factor negative regulatory protein HHJ45_06260 ENOG4105VQK sigma E regulatory protein, MucB RseB HHJ45_06265 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HHJ45_06275 ENOG4105C3F Signal peptidase i HHJ45_06295 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HHJ45_06310 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HHJ45_06315 ENOG4106G6Q Transcriptional regulator HHJ45_06320 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HHJ45_06325 ENOG4108Z6B deaminase HHJ45_06340 ENOG4107WP9 Histidine kinase HHJ45_06345 ENOG4108SKK alpha helix protein HHJ45_06350 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ45_06360 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ45_06370 ENOG4108NZE NAGC-like transcriptional regulator HHJ45_06380 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HHJ45_06385 ENOG4108F37 ATP-binding component of a transport system HHJ45_06390 ENOG4105CNN ABC, transporter HHJ45_06395 ENOG4105CPQ Dehydrogenase HHJ45_06400 ENOG4108ZKT aldose 1-epimerase HHJ45_06405 ENOG4108SB3 DoxX Family HHJ45_06430 ENOG4105FUY alpha subunit HHJ45_06435 ENOG4108W5M transcriptional regulator HHJ45_06440 ENOG4105D8G Major Facilitator superfamily HHJ45_06445 ENOG4108MN2 Stationary phase inducible protein CsiE HHJ45_06450 ENOG4107XM9 (LipO)protein HHJ45_06455 ENOG4105ECY inositol monophosphatase HHJ45_06475 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HHJ45_06495 ENOG4108ZIT Ferredoxin, 2FE-2S HHJ45_06500 ENOG4105WVQ Fe-S assembly protein IscX HHJ45_06510 ENOG4105YYA enhanced serine sensitivity protein SseB HHJ45_06515 ENOG4105KHC sulfurtransferase HHJ45_06520 ENOG4105DN3 alpha-2-macroglobulin domain protein HHJ45_06525 ENOG4108JQB penicillin-binding protein 1C HHJ45_06555 ENOG4105N21 Membrane HHJ45_06570 ENOG4105VPD cellular component movement HHJ45_06580 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HHJ45_06590 ENOG41066DY Membrane HHJ45_06595 ENOG4108ZMA Outer membrane lipoprotein HHJ45_06600 ENOG41062G3 Protein of unknown function (DUF2633) HHJ45_06610 ENOG4105BZU Histidine kinase HHJ45_06615 ENOG4105C9X ppx gppa phosphatase HHJ45_06620 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HHJ45_06625 ENOG4108V3E phosphoribosylglycinamide formyltransferase HHJ45_06640 ENOG4105C2W permease HHJ45_06645 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HHJ45_06650 ENOG4105K89 arsenate reductase HHJ45_06655 ENOG4105ERG peptidase m48, ste24p HHJ45_06660 ENOG4105C02 permease HHJ45_06675 ENOG4105I6X formate hydrogenlyase maturation HHJ45_06690 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ45_06695 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ45_06700 ENOG4107WQX hydrogenase 4 membrane subunit HHJ45_06710 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ45_06715 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ45_06720 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ45_06725 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ45_06730 ENOG4105RH4 Glycine cleavage system transcriptional repressor HHJ45_06740 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ45_06755 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HHJ45_06760 ENOG4105CGZ zinc metallopeptidase HHJ45_06770 ENOG4106KED esterase YpfH HHJ45_06785 ENOG4105KUZ arsenate reductase HHJ45_06795 ENOG4105BZS acriflavin resistance protein HHJ45_06800 ENOG4105BZU Histidine kinase HHJ45_06805 ENOG4105BZ8 glutamate synthase HHJ45_06815 ENOG4108PVD exported protein HHJ45_06820 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ45_06825 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ45_06830 ENOG4105C6K Malic enzyme HHJ45_06835 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HHJ45_06840 ENOG4106S4J ethanolamine utilization protein EutP HHJ45_06845 ENOG4105NDK ethanolamine utilization protein HHJ45_06850 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HHJ45_06855 ENOG4107WUY phosphate acetyltransferase HHJ45_06860 ENOG4105KNY Microcompartments protein HHJ45_06865 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ45_06870 ENOG4108EKI Dehydrogenase HHJ45_06875 ENOG4107RWI ethanolamine utilization protein eutJ HHJ45_06880 ENOG4105C0A alcohol dehydrogenase HHJ45_06885 ENOG4105ENY Ethanolamine utilization protein eutH HHJ45_06890 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HHJ45_06895 ENOG4105CPD ethanolamine ammonia-lyase HHJ45_06905 ENOG4106D67 ethanolamine utilization protein HHJ45_06910 ENOG4108X49 Ethanolamine utilization protein EutK HHJ45_06915 ENOG4108K3Z AraC family transcriptional regulator HHJ45_06925 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HHJ45_06935 ENOG4105QZU Inner membrane protein YfeZ HHJ45_06940 ENOG4105E7K (LipO)protein HHJ45_06945 ENOG4105EZR dyp-type peroxidase family protein HHJ45_06950 ENOG4107S1E Beta-lactamase HHJ45_06955 ENOG4105C5Y PTS System HHJ45_06970 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HHJ45_06975 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HHJ45_06980 ENOG4108I5D sulfate abc transporter HHJ45_06985 ENOG4105ECW sulfate abc transporter HHJ45_06990 ENOG4108IJ6 ABC transporter HHJ45_06995 ENOG4105C6T cysteine synthase HHJ45_07000 ENOG4105M0Y HHJ45_07010 ENOG4105C5Y PTS System HHJ45_07015 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ45_07025 ENOG4105C6T cysteine synthase HHJ45_07045 ENOG4105VRT cytoplasmic protein HHJ45_07050 ENOG4105DHU Bile acid HHJ45_07055 ENOG4108M0I Transcriptional regulator HHJ45_07060 ENOG4108NFH Sugar hydrolase HHJ45_07065 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HHJ45_07070 ENOG4105EAA nucleoside HHJ45_07080 ENOG4105CN8 Transcriptional regulator HHJ45_07120 ENOG4105GXM Putative transcription regulator (DUF1323) HHJ45_07125 ENOG4105HZG regulatoR HHJ45_07140 ENOG4108KMM Diguanylate cyclase HHJ45_07145 ENOG4105D9N nucleoside HHJ45_07155 ENOG4109076 Conserved Protein HHJ45_07160 ENOG4105VCT ion-transport protein YfeO HHJ45_07170 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ45_07175 ENOG410863U PTS System HHJ45_07180 ENOG4105DC7 peptidase M24 HHJ45_07185 ENOG4105CN9 Peptidase m42 family protein HHJ45_07190 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ45_07195 ENOG4108CIP transcriptional regulator HHJ45_07200 ENOG4105DY9 regulatoR HHJ45_07205 ENOG4108HRK Histidine kinase HHJ45_07210 ENOG4105CHM Aminotransferase HHJ45_07220 ENOG4105D1S lipid A biosynthesis HHJ45_07225 ENOG4105W9M Membrane HHJ45_07235 ENOG4108V08 YfdX protein HHJ45_07245 ENOG4105CFN oxalyl-CoA decarboxylase HHJ45_07250 ENOG4108N2Y auxin Efflux HHJ45_07255 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HHJ45_07260 ENOG4105BZU Histidine kinase HHJ45_07265 ENOG4108WQH regulatoR HHJ45_07270 ENOG4105CW7 secretion protein, HlyD family HHJ45_07275 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ45_07290 ENOG4106NDP Transcriptional regulator HHJ45_07295 ENOG4108HKT sucrose-6-phosphate hydrolase HHJ45_07300 ENOG4105D7K pfkb domain protein HHJ45_07305 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ45_07335 ENOG41077V0 CPS-53 (KpLE1) prophage HHJ45_07355 ENOG4108PNI recT protein HHJ45_07420 ENOG4105NY2 NinB protein HHJ45_07450 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ45_07480 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HHJ45_07490 ENOG4108N0N Phage Terminase Large Subunit HHJ45_07495 ENOG4107ZQ5 Phage-associated protein, HI1409 family HHJ45_07635 ENOG4105DFP Integrase HHJ45_07645 ENOG4105S64 Formate nitrite transporter HHJ45_07650 ENOG410903C (LipO)protein HHJ45_07665 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HHJ45_07670 ENOG4105KZW UPF0381 protein HHJ45_07685 ENOG4108BY2 phosphohistidine phosphatase HHJ45_07695 ENOG4106PG1 outer membrane usher protein HHJ45_07700 ENOG4108FZ9 Chaperone HHJ45_07705 ENOG4105NEV Fimbrial HHJ45_07710 ENOG4105UGQ Fimbrial HHJ45_07715 ENOG4105US4 fimbrial-like protein yfcP HHJ45_07745 ENOG4105EJ9 Membrane HHJ45_07750 ENOG4108BPE -transporting atpase HHJ45_07755 ENOG4105MH2 YfcL protein HHJ45_07760 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HHJ45_07765 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ45_07770 ENOG4105F9N Major Facilitator Superfamily HHJ45_07775 ENOG4106WZ1 flagella biosynthesis regulator HHJ45_07785 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ45_07795 ENOG4105DQR SNARE associated Golgi HHJ45_07805 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HHJ45_07810 ENOG4108S3P Sporulation domain protein HHJ45_07815 ENOG4105E96 Colicin v production protein HHJ45_07820 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HHJ45_07825 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ45_07830 ENOG4105E89 ABC transporter HHJ45_07835 ENOG4105E89 ABC transporter HHJ45_07840 ENOG4105DSP amino acid AbC transporter HHJ45_07845 ENOG4106YG3 ABC transporter HHJ45_07850 ENOG4108JEH abc transporter atp-binding protein HHJ45_07855 ENOG4105DNE Transposase HHJ45_07860 ENOG4105ECP epimerase HHJ45_07865 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HHJ45_07870 ENOG4105CYM Glutathione S-transferase HHJ45_07875 ENOG4108SHQ Glutathione S-transferase HHJ45_07880 ENOG4108RE9 Phosphodiesterase HHJ45_07885 ENOG4105PTV Nudix Hydrolase HHJ45_07890 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ45_07895 ENOG4105C6K Malic enzyme HHJ45_07900 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ45_07910 ENOG4105XWI UPF0304 protein HHJ45_07915 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HHJ45_07920 ENOG4107QWE )-transporter HHJ45_07930 ENOG4105CHM Aminotransferase HHJ45_07935 ENOG4107NQ8 LysR family Transcriptional regulator HHJ45_07955 ENOG4105GKE subunit e HHJ45_07960 ENOG4107QIZ NADH dehydrogenase HHJ45_07965 ENOG4108IEH NADH dehydrogenase subunit g HHJ45_07980 ENOG4107UFS subunit j HHJ45_07990 ENOG4105D65 subunit l HHJ45_07995 ENOG4105C8S subunit m HHJ45_08005 ENOG4105GDX Domain of unknown function (DUF1877) HHJ45_08025 ENOG4107YB6 acetyltransferase, (GNAT) family HHJ45_08030 ENOG4105TNS Conserved Protein HHJ45_08035 ENOG4105E4F Isochorismate synthase HHJ45_08050 ENOG4108IPT Naphthoate synthase HHJ45_08060 ENOG4105CEY Amp-dependent synthetase and ligase HHJ45_08065 ENOG4106GZG polymyxin resistance protein B HHJ45_08115 ENOG4108UII YfaZ family HHJ45_08120 ENOG4108EWA cinA-like protein HHJ45_08130 ENOG4105DNE Transposase HHJ45_08135 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ45_08145 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HHJ45_08150 ENOG4105CXY transporter HHJ45_08155 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HHJ45_08165 ENOG4105FQR PH-inducible protein involved in stress response HHJ45_08170 ENOG4105XPH Ferredoxin HHJ45_08175 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ45_08180 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ45_08200 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ45_08205 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HHJ45_08210 ENOG4108QJJ Protein of unknown function (DUF1175) HHJ45_08215 ENOG4107S52 alpha-2-macroglobulin domain protein HHJ45_08220 ENOG41081SK signal peptide protein HHJ45_08225 ENOG4105EDV vault protein HHJ45_08230 ENOG4105BZU Histidine kinase HHJ45_08235 ENOG41068CG regulatoR HHJ45_08240 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HHJ45_08245 ENOG4105FCK Membrane HHJ45_08250 ENOG4105CJ2 (LipO)protein HHJ45_08255 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ45_08260 ENOG4105CF1 Alkylated DNA repair protein HHJ45_08265 ENOG4105IBP Cyclic peptide transporter HHJ45_08285 ENOG4108ZNS ferredoxin-type protein NapF HHJ45_08290 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HHJ45_08300 ENOG4108BGM Quinol dehydrogenase periplasmic component HHJ45_08305 ENOG4105GXZ Ferredoxin-type protein NapH HHJ45_08310 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HHJ45_08315 ENOG4105CUW cytochrome C-TYPE protein HHJ45_08320 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HHJ45_08325 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HHJ45_08330 ENOG41060IM Heme exporter protein HHJ45_08335 ENOG4105X3C heme exporter protein HHJ45_08345 ENOG4105DA4 cytochrome c-type biogenesis protein HHJ45_08350 ENOG4107QX9 Thiol disulfide interChange protein HHJ45_08355 ENOG4105KWW Biogenesis protein HHJ45_08360 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ45_08375 ENOG4105E68 Sulfatase HHJ45_08395 ENOG4105CFI type iii restriction protein res subunit HHJ45_08400 ENOG4105I08 Pseudouridine synthase HHJ45_08405 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ45_08410 ENOG4105HG6 HHJ45_08415 ENOG4108JQ5 ABC transporter HHJ45_08420 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HHJ45_08425 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HHJ45_08430 ENOG4105E43 Extracellular solute-binding protein, family 5 HHJ45_08435 ENOG4105CXC rtn protein HHJ45_08440 ENOG4107TT5 NLP P60 protein HHJ45_08445 ENOG41076MN Phosphoesterase, PA-phosphatase related HHJ45_08450 ENOG4105CKI cobalamin synthesis protein HHJ45_08455 ENOG4105DEI Mannitol dehydrogenase HHJ45_08465 ENOG4105KRS Proteinase inhibitor HHJ45_08470 ENOG4105S8Q sugar efflux transporter HHJ45_08475 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HHJ45_08480 ENOG4105DE4 1-phosphofructokinase HHJ45_08485 ENOG4105DM4 PTS System HHJ45_08490 ENOG4105DD7 kinase (PfkB family HHJ45_08495 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HHJ45_08500 ENOG4105D9N nucleoside HHJ45_08505 ENOG4108Y4K DNA-binding transcriptional activator HHJ45_08515 ENOG4105D9N nucleoside HHJ45_08520 ENOG4105DD7 kinase (PfkB family HHJ45_08530 ENOG4105HMI Membrane HHJ45_08535 ENOG4105DUM transcriptional regulator, lysR family HHJ45_08540 ENOG4108IQI permease HHJ45_08545 ENOG4105D05 Receptor HHJ45_08560 ENOG4105DHF Membrane HHJ45_08565 ENOG41060NJ transcriptional regulator HHJ45_08570 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HHJ45_08575 ENOG4105C2J ABC transporter HHJ45_08580 ENOG4108HWV )-transporter HHJ45_08585 ENOG4107SJI Dehydrogenase HHJ45_08590 ENOG4105BZ8 glutamate synthase HHJ45_08595 ENOG4105Y9N Membrane HHJ45_08600 ENOG4107GZ4 SanA protein HHJ45_08610 ENOG41067MG lrgb family HHJ45_08620 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HHJ45_08630 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ45_08635 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HHJ45_08640 ENOG4105KHU inner membrane protein YohD HHJ45_08645 ENOG41069YE inner membrane protein yohC HHJ45_08650 ENOG41061WM D-Alanyl-D-Alanine HHJ45_08655 ENOG4105CXG d-lactate dehydrogenase HHJ45_08660 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HHJ45_08665 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HHJ45_08670 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HHJ45_08675 ENOG4108IJ8 ABC transporter HHJ45_08680 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HHJ45_08695 ENOG4108HRK Histidine kinase HHJ45_08700 ENOG4108NEV two component transcriptional regulator, LytTR family HHJ45_08705 ENOG4108W15 Protein of unknown function (DUF1456) HHJ45_08710 ENOG4108YCW (LipO)protein HHJ45_08715 ENOG410903U zinc ion binding HHJ45_08720 ENOG4105DEG Vwa containing coxe family protein HHJ45_08725 ENOG4105RD5 HHJ45_08730 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HHJ45_08740 ENOG4108KDT Molybdate metabolism regulator HHJ45_08745 ENOG4108KDT Molybdate metabolism regulator HHJ45_08755 ENOG4105D1F ATP-binding protein HHJ45_08760 ENOG41067AK Protein of unknown function (DUF2574) HHJ45_08765 ENOG41063W2 Fimbrial protein HHJ45_08770 ENOG4108MQF Chaperone HHJ45_08775 ENOG4105CW0 outer membrane usher protein HHJ45_08780 ENOG410662B Type-1 fimbrial protein HHJ45_08785 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HHJ45_08805 ENOG4105DWF phosphomethylpyrimidine kinase HHJ45_08810 ENOG4108UQ1 hydrolase, family 25 HHJ45_08815 ENOG4105FDP GntR family transcriptional regulator HHJ45_08820 ENOG4108TFM Kinase, PfkB family HHJ45_08825 ENOG4108KD5 ADP-ribosylation crystallin J1 HHJ45_08830 ENOG4105EAA nucleoside HHJ45_08835 ENOG4105EIE fructose-bisphosphate aldolase HHJ45_08850 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HHJ45_08855 ENOG41090UW PTS System HHJ45_08860 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ45_08865 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HHJ45_08880 ENOG41076Z6 Uncharacterized protein yegR HHJ45_08885 ENOG4105CFP Peptidase U32 HHJ45_08890 ENOG4105KWI UPF0339 protein HHJ45_08895 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ45_08900 ENOG4105EB3 Histidine kinase HHJ45_08915 ENOG4105BZS acriflavin resistance protein HHJ45_08935 ENOG4108M24 von Willebrand factor, type A HHJ45_08940 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HHJ45_08945 ENOG4105ZD5 Uncharacterized protein conserved in bacteria (DUF2314) HHJ45_08950 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HHJ45_08955 ENOG4105R8A Heat shock protein HHJ45_08960 ENOG4105D03 DNA-3-methyladenine glycosylase II HHJ45_08970 ENOG4105DBI uridine monophosphokinase HHJ45_08980 ENOG4108GAE asmA family HHJ45_08985 ENOG4105EE5 Membrane protein terC HHJ45_08990 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ45_08995 ENOG4105MH5 phosphoesterase PA-phosphatase related protein HHJ45_09005 ENOG4108MRJ HHJ45_09010 ENOG4105DAY polysaccharide export protein HHJ45_09070 ENOG4105C30 Nad-dependent epimerase dehydratase HHJ45_09080 ENOG4106CD9 glycosyl transferase group 1 HHJ45_09090 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HHJ45_09135 ENOG4105EY8 ABC transporter HHJ45_09140 ENOG4108KQJ Type 11 methyltransferase HHJ45_09150 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) HHJ45_09160 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HHJ45_09175 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HHJ45_09180 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HHJ45_09205 ENOG4105VTW prevent-host-death family HHJ45_09210 ENOG4105KRQ Addiction module toxin, Txe YoeB family HHJ45_09215 ENOG4107SRH Nad-dependent epimerase dehydratase HHJ45_09220 ENOG4105EQ1 Transcriptional regulator HHJ45_09230 ENOG4105CUB amino acid HHJ45_09245 ENOG4105CJB Exodeoxyribonuclease I HHJ45_09250 ENOG4105DZ1 carboxypeptidase HHJ45_09260 ENOG4105DR8 Membrane HHJ45_09295 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ45_09305 ENOG4108YGG dna repair protein HHJ45_09310 ENOG4105MFG Antirestriction protein HHJ45_09315 ENOG4106H6R UPF0380 protein HHJ45_09335 ENOG4108YIV HHJ45_09340 ENOG4108F5E vimentin HHJ45_09410 ENOG41080QX K07048 phosphotriesterase-related protein HHJ45_09450 ENOG4108YZT Adenosylcobinamide kinase HHJ45_09465 ENOG4108PXI ErfK YbiS YcfS YnhG HHJ45_09475 ENOG4106P55 Transcriptional regulator HHJ45_09480 ENOG4107R11 Transcriptional regulator HHJ45_09490 ENOG4105UQX Mate efflux family protein HHJ45_09500 ENOG4105CDY transcriptional regulatory protein HHJ45_09505 ENOG4105FYV Amp nucleosidase HHJ45_09510 ENOG4105CSH Transporter HHJ45_09520 ENOG4105TNG K13735 adhesin invasin HHJ45_09525 ENOG4105TNG K13735 adhesin invasin HHJ45_09530 ENOG4105TNG K13735 adhesin invasin HHJ45_09535 ENOG4107ZSV Receptor HHJ45_09540 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ45_09560 ENOG4105C0W non-ribosomal peptide synthetase HHJ45_09575 ENOG4105BZ1 (ABC) transporter HHJ45_09580 ENOG4105EYM Major Facilitator superfamily HHJ45_09675 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HHJ45_09680 ENOG4108MXB Protein of unknown function (DUF968) HHJ45_09745 ENOG4105CAR Terminase, large subunit HHJ45_09750 ENOG4105EFC phage portal protein HK97 family HHJ45_09755 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) HHJ45_09870 ENOG4108MEK Metal-binding protein YodA HHJ45_09875 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) HHJ45_09885 ENOG4105VT2 5-hydroxyisourate hydrolase HHJ45_09890 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ45_09895 ENOG4107ZY3 Histidine kinase HHJ45_09905 ENOG4105ZIT Porin Gram-negative type HHJ45_09910 ENOG4105Y0K Inner membrane protein YedR HHJ45_09915 ENOG4105EST Metal Dependent Phosphohydrolase HHJ45_09920 ENOG4105DVF Cytosine-specific methyltransferase HHJ45_09925 ENOG41090BB DNA mismatch endonuclease (vsr) HHJ45_09930 ENOG4105FDR Membrane HHJ45_09935 ENOG4105CKW Inner membrane protein yedI HHJ45_09940 ENOG4105VNZ cytoplasmic protein HHJ45_09955 ENOG4105YX3 cellular response to acidity HHJ45_09965 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HHJ45_09970 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HHJ45_09980 ENOG4105CN7 Flagellar biosynthetic protein FliP HHJ45_09985 ENOG4105K0P flagellar biosynthesis protein HHJ45_09990 ENOG4105DD5 Flagellar motor switch protein HHJ45_09995 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ45_10000 ENOG4107ZI8 flagellar basal body-associated protein flil HHJ45_10005 ENOG4105WF4 Flagellar hook-length control protein HHJ45_10010 ENOG4105GSA Flagellar export protein flij HHJ45_10015 ENOG4108JIR Flagellum-specific ATP synthase HHJ45_10025 ENOG41090PJ Flagellar assembly protein HHJ45_10030 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ45_10035 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HHJ45_10040 ENOG4105VQ0 flagellar hook-basal body complex protein fliE HHJ45_10045 ENOG4108RAV Conserved protein HHJ45_10055 ENOG41066VF YeeE YedE family protein HHJ45_10060 ENOG4108W9D (LipO)protein HHJ45_10065 ENOG4105E5K Alpha-amylase HHJ45_10070 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) HHJ45_10075 ENOG4105MQ3 flagellar protein FliS HHJ45_10080 ENOG4105DTS flagellar hook-associated HHJ45_10085 ENOG4105I03 Flagellin HHJ45_10090 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ45_10095 ENOG4108M9K flagella biosynthesis protein FliZ HHJ45_10100 ENOG4105EAB amino acid AbC transporter HHJ45_10105 ENOG4105K6H D-cysteine desulfhydrase HHJ45_10110 ENOG4105E5Q amino acid AbC transporter HHJ45_10115 ENOG4105CDA abc transporter atp-binding protein HHJ45_10120 ENOG4105VJY transcriptional regulator HHJ45_10125 ENOG4105XVG cytoplasmic protein HHJ45_10135 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ45_10165 ENOG4106RHG Yeca family HHJ45_10170 ENOG4105E0U tyrosine-specific transport protein HHJ45_10175 ENOG4105VVZ metal-binding protein HHJ45_10180 ENOG41090A1 ferritin HHJ45_10185 ENOG4105P23 (LipO)protein HHJ45_10195 ENOG4105N4N Protein of unknown function (DUF2766) HHJ45_10200 ENOG4108UEC Ferritin-like protein HHJ45_10205 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HHJ45_10210 ENOG4105C2J ABC transporter HHJ45_10215 ENOG4105CNN ABC, transporter HHJ45_10220 ENOG4108K4C ec 3.1.3.12 HHJ45_10230 ENOG4108VA4 Universal stress protein HHJ45_10240 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HHJ45_10245 ENOG4107RD7 Flagellar Motor Protein, MotA HHJ45_10250 ENOG4105ER2 Ompa motb domain protein HHJ45_10255 ENOG4105CBS Chea signal transduction histidine kinase HHJ45_10260 ENOG4108V3W Chemotaxis protein, CheW HHJ45_10265 ENOG4105C8Q Methyl-accepting chemotaxis HHJ45_10270 ENOG4105C8Q Methyl-accepting chemotaxis HHJ45_10275 ENOG4105BZU Histidine kinase HHJ45_10280 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) HHJ45_10285 ENOG4108VYJ response regulator receiver protein HHJ45_10290 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HHJ45_10295 ENOG4105D00 flagellar biosynthetic protein flhB HHJ45_10300 ENOG4105D7B Flagellar biosynthesis protein flha HHJ45_10305 ENOG4105W13 flagellar protein HHJ45_10315 ENOG4105C75 arginyL-tRNA synthetase HHJ45_10320 ENOG4106ZCM YecM protein HHJ45_10330 ENOG4105CUW cytochrome C-TYPE protein HHJ45_10355 ENOG4105WJG Glutathione HHJ45_10360 ENOG41081XQ Conserved Protein HHJ45_10365 ENOG4105D3W isochorismatase HHJ45_10375 ENOG4108TIT dATP pyrophosphohydrolase HHJ45_10380 ENOG4105CDY transcriptional regulatory protein HHJ45_10390 ENOG4107S01 Repressor protein MetJ HHJ45_10405 ENOG4105FAV ABC, transporter HHJ45_10415 ENOG4105NXV High-affinity zinc uptake system protein HHJ45_10420 ENOG4105DR5 peptidase HHJ45_10425 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ45_10430 ENOG4105CA9 Pyruvate kinase HHJ45_10435 ENOG4106KNT transcriptional regulator HHJ45_10440 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HHJ45_10445 ENOG4105C01 Dihydroxy-acid dehydratase HHJ45_10450 ENOG4108UHU Aldolase HHJ45_10460 ENOG4105X2V dna damage-inducible protein HHJ45_10470 ENOG4108Q2J Inner membrane protein YebE HHJ45_10475 ENOG4105CUG Oligopeptidase b HHJ45_10480 ENOG4105UMD exodeoxyribonuclease X HHJ45_10485 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ45_10490 ENOG4105MPK DNA polymerase III subunit theta HHJ45_10495 ENOG4105FXM Copper resistance protein HHJ45_10500 ENOG4108PNC copper resistance HHJ45_10505 ENOG4105NKT exported protein HHJ45_10510 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ45_10515 ENOG4105UVW uncharacterized protein yebW HHJ45_10520 ENOG4105WT8 Protein of unknown function (DUF1480) HHJ45_10530 ENOG4105DY2 Paraquat-inducible protein b HHJ45_10535 ENOG4105H2K paraquat-inducible protein a HHJ45_10540 ENOG4108ZGC gaf domain protein HHJ45_10550 ENOG4105CN1 protease HHJ45_10560 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ45_10565 ENOG4105J4Q Transcriptional regulator HHJ45_10570 ENOG4105TIK HHJ45_10580 ENOG4105Q3Y exported protein HHJ45_10595 ENOG4105DHI Methyltransferase HHJ45_10610 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ45_10615 ENOG4105ETZ PTS System HHJ45_10620 ENOG4105DAS pts system HHJ45_10625 ENOG4105EE5 Membrane protein terC HHJ45_10630 ENOG4107XTP (EAL) domain protein HHJ45_10635 ENOG4105EJQ L-serine dehydratase HHJ45_10645 ENOG4105CRQ synthase (Component I) HHJ45_10655 ENOG4105V2F Uncharacterized protein yoac HHJ45_10665 ENOG4105M4H endoribonuclease L-psp HHJ45_10670 ENOG4105DVT helicase HHJ45_10675 ENOG41072GX Peptidase M22 Glycoprotease HHJ45_10680 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ45_10685 ENOG4105CEY Amp-dependent synthetase and ligase HHJ45_10690 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HHJ45_10695 ENOG4105E3J oxidoreductase HHJ45_10700 ENOG4105DVW rieske (2Fe-2S) HHJ45_10705 ENOG4105C94 Transporter HHJ45_10710 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HHJ45_10715 ENOG4105EJC lysr family transcriptional regulator HHJ45_10735 ENOG4105Y3U Transglycosylase-associated protein HHJ45_10745 ENOG4106G4W HHJ45_10750 ENOG410620I Diguanylate cyclase HHJ45_10755 ENOG4105UCG Domain of unknown function (DUF333) HHJ45_10760 ENOG4105K78 MarR family Transcriptional regulator HHJ45_10770 ENOG4105R1U AraC Family Transcriptional Regulator HHJ45_10785 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HHJ45_10790 ENOG4108KHP Diguanylate cyclase HHJ45_10805 ENOG4105CYN Serine protein kinase HHJ45_10810 ENOG4105GNX MltA-interacting MipA family protein HHJ45_10815 ENOG4105CV8 reductase HHJ45_10820 ENOG4105DSB aldose 1-epimerase HHJ45_10825 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ45_10835 ENOG4105VUT cytoplasmic protein HHJ45_10840 ENOG4108RWI nicotinamidase HHJ45_10845 ENOG4105HDK L-asparaginase HHJ45_10850 ENOG4105D07 Signal peptide peptidase, SppA HHJ45_10855 ENOG41069NU Nitroreductase HHJ45_10865 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ45_10875 ENOG4105D82 Glutamate dehydrogenase HHJ45_10880 ENOG4105MTM Protein of unknown function (DUF1496) HHJ45_10885 ENOG4105M6F mutator MutT protein HHJ45_10890 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HHJ45_10895 ENOG4107RM6 sulfurtransferase HHJ45_10900 ENOG4108VGW abc transporter atp-binding protein HHJ45_10905 ENOG4105CXZ ABC transporter, permease HHJ45_10910 ENOG4105VNH ABC transporter solute-binding protein HHJ45_10915 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ45_10920 ENOG4108N5C SNARE associated Golgi protein-related protein HHJ45_10925 ENOG4108KCW iron-sulfur cluster binding HHJ45_10930 ENOG4108RSN SNARE associated Golgi HHJ45_10935 ENOG4105CGK Exodeoxyribonuclease III HHJ45_10965 ENOG4108SPG Periplasmic Protein HHJ45_10975 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HHJ45_10985 ENOG4105KKI DNA-binding transcriptional activator OsmE HHJ45_10990 ENOG4105VZJ PTS System HHJ45_10995 ENOG4105CK1 PTS System HHJ45_11000 ENOG4105VCP PTS System HHJ45_11005 ENOG4105EZV Transcriptional regulator HHJ45_11010 ENOG4105F8D glycoside hydrolase family 4 HHJ45_11020 ENOG4105CH6 catalase HHJ45_11040 ENOG4108ETY sodium dicarboxylate symporter HHJ45_11045 ENOG4107K5X Membrane-bound metal-dependent hydrolase HHJ45_11050 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HHJ45_11055 ENOG4107PN8 YfeABCD locus regulator HHJ45_11065 ENOG4105P10 Uncharacterized protein ydiZ HHJ45_11070 ENOG4105DE4 1-phosphofructokinase HHJ45_11075 ENOG4108NE3 Salt-induced outer membrane protein HHJ45_11095 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HHJ45_11100 ENOG41082NX 50s ribosomal protein l35 HHJ45_11135 ENOG4108V06 Glutathione peroxidase HHJ45_11145 ENOG4108QBX (LipO)protein HHJ45_11150 ENOG4108TC0 Diguanylate phosphodiesterase HHJ45_11165 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ45_11175 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HHJ45_11180 ENOG4105CEY Amp-dependent synthetase and ligase HHJ45_11185 ENOG41090P5 ferredoxin-like protein HHJ45_11190 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ45_11195 ENOG4105C10 Electron transfer flavoprotein HHJ45_11200 ENOG4105CV7 Electron transfer flavoprotein HHJ45_11205 ENOG4105W4W Transcriptional regulator HHJ45_11210 ENOG4105C1G acyl-Coa dehydrogenase HHJ45_11215 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ45_11230 ENOG4105EMV Major Facilitator HHJ45_11235 ENOG4105EMV Major Facilitator HHJ45_11240 ENOG4105SUA Ydil protein HHJ45_11250 ENOG4105IPI Membrane HHJ45_11255 ENOG4105CQB FAD linked oxidase domain protein HHJ45_11260 ENOG4105KA0 thioesterase Superfamily protein HHJ45_11265 ENOG410671Z uncharacterized protein ydiH HHJ45_11270 ENOG4108Z4V iron-sulfur cluster assembly HHJ45_11275 ENOG4105DIW FeS assembly protein SUFB HHJ45_11280 ENOG4105C3K feS assembly ATPase SufC HHJ45_11285 ENOG4105JRK feS assembly protein SufD HHJ45_11300 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ45_11305 ENOG4105KMX major outer membrane lipoprotein HHJ45_11310 ENOG4105CA9 Pyruvate kinase HHJ45_11315 ENOG4105RFR Protein of unknown function (DUF2767) HHJ45_11325 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HHJ45_11330 ENOG4105JVW HHJ45_11335 ENOG4108393 oxidoreductase Fe-S subunit HHJ45_11340 ENOG4108NWD Cytochrome HHJ45_11345 ENOG4108Y7C Conserved Protein HHJ45_11350 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HHJ45_11355 ENOG4105N0V mono-oxygenase ydhR HHJ45_11380 ENOG4108R6K riboflavin synthase, subunit alpha HHJ45_11385 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HHJ45_11390 ENOG4105CZQ inner membrane transport protein YdhC HHJ45_11395 ENOG4105F52 Transcriptional regulator HHJ45_11410 ENOG4105F27 Major Facilitator HHJ45_11415 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ45_11420 ENOG4105K4H Nlp p60 protein HHJ45_11425 ENOG4105M2J Glutaredoxin HHJ45_11430 ENOG4107QRT dEAD DEAH box helicase HHJ45_11440 ENOG4108UYE Lactoylglutathione lyase HHJ45_11445 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ45_11450 ENOG4108WUH Transcriptional regulator, TetR family HHJ45_11455 ENOG4105XZD Fe-S protein HHJ45_11460 ENOG4107RGM aldo keto reductase HHJ45_11465 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ45_11470 ENOG4105DSW Fusaric acid resistance protein HHJ45_11475 ENOG4105Y49 secretion protein, HlyD family HHJ45_11490 ENOG4108XTF Outer Membrane Lipoprotein HHJ45_11500 ENOG410642K Lysozyme inhibitor HHJ45_11515 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HHJ45_11520 ENOG4108K3A Glutathione S-transferase HHJ45_11525 ENOG4105DUX Transporter HHJ45_11530 ENOG4105CSM endonuclease III HHJ45_11540 ENOG4108UQQ Electron transport complex HHJ45_11565 ENOG4105M9B inner membrane protein ydgK HHJ45_11570 ENOG4105QZ5 OriC-binding nucleoid-associated protein HHJ45_11575 ENOG4106C6R beta-lactam resistance protein HHJ45_11580 ENOG4105D9R oxidoreductase HHJ45_11590 ENOG4105C87 Aminotransferase class I and II HHJ45_11595 ENOG4105CI1 PTS System HHJ45_11600 ENOG4107P2S Transcriptional regulator HHJ45_11605 ENOG4107ZQV short-chain dehydrogenase reductase HHJ45_11610 ENOG4105XEA Tetr family transcriptional regulator HHJ45_11615 ENOG4105CNT hydrolase family 2 HHJ45_11620 ENOG4105CT4 transporter HHJ45_11625 ENOG4108QNI outer membrane porin protein HHJ45_11630 ENOG4106J39 exported protein HHJ45_11635 ENOG4105EIP mannose-6-phosphate isomerase HHJ45_11640 ENOG4107GFK fumarate HHJ45_11645 ENOG4105C9Q fumarate hydratase class II HHJ45_11655 ENOG4105JJR Histidine kinase HHJ45_11660 ENOG4107EXC regulatoR HHJ45_11665 ENOG4105RA2 Membrane HHJ45_11675 ENOG4105D5Q Arginine ornithine antiporter HHJ45_11680 ENOG4105C5D exported protein HHJ45_11685 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ45_11690 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ45_11695 ENOG4105DSF transport protein HHJ45_11710 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HHJ45_11725 ENOG4105D94 Major Facilitator Superfamily HHJ45_11730 ENOG4106NZI LysR family Transcriptional regulator HHJ45_11735 ENOG4105DAG ROK family HHJ45_11740 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ45_11750 ENOG4108NEM leader-binding protein dmsD HHJ45_11755 ENOG4107KGK dmso reductase anchor subunit HHJ45_11760 ENOG4105QAX Iron-sulfur HHJ45_11765 ENOG4105C3J Cysteine desulfurase HHJ45_11770 ENOG4107QY8 reductase HHJ45_11775 ENOG4105KBG Protein of unknown function (DUF1161) HHJ45_11780 ENOG4105D69 UPF0257 lipoprotein ynfC HHJ45_11785 ENOG4108MK9 spermidine N(1)-acetyltransferase HHJ45_11800 ENOG4105CXK mandelate racemase muconate lactonizing HHJ45_11805 ENOG4105CPQ Dehydrogenase HHJ45_11830 ENOG41061EV selenium-binding protein YdfZ HHJ45_11835 ENOG4107XBN GntR Family Transcriptional Regulator HHJ45_11840 ENOG4105EMU Dehydrogenase HHJ45_11845 ENOG4105DGW oligopeptidase A HHJ45_11850 ENOG4108WTK competence damage-inducible protein HHJ45_11855 ENOG4108YDI single-species biofilm formation on inanimate substrate HHJ45_11860 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HHJ45_11870 ENOG4105E5W Transporter HHJ45_11875 ENOG4108594 Permease of the drug metabolite transporter HHJ45_11880 ENOG4105FDP GntR family transcriptional regulator HHJ45_11890 ENOG4105CK1 PTS System HHJ45_11895 ENOG4105VCP PTS System HHJ45_11905 ENOG4105CS2 ec 3.2.1.21 HHJ45_11910 ENOG4106DNR multiple antibiotic resistance protein HHJ45_11915 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HHJ45_11920 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HHJ45_11940 ENOG4105EGI Transcriptional regulator HHJ45_11945 ENOG4105C26 Dehydrogenase HHJ45_11950 ENOG4105CSV Glutaminase HHJ45_11955 ENOG4105M0C cytoplasmic protein HHJ45_11960 ENOG4105BZU Histidine kinase HHJ45_11970 ENOG4105FFC UPF0187 protein HHJ45_11975 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) HHJ45_11980 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HHJ45_12005 ENOG4105C2J ABC transporter HHJ45_12025 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HHJ45_12030 ENOG4105CAF HipA N-terminal domain protein HHJ45_12040 ENOG4108RQP Major type 1 subunit fimbrin HHJ45_12050 ENOG4105CW0 outer membrane usher protein HHJ45_12055 ENOG4108WDE Fimbrial protein HHJ45_12060 ENOG4106318 fimbrial-like protein YdeR HHJ45_12065 ENOG4106PIH fimbrial-like protein ydeQ HHJ45_12070 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HHJ45_12085 ENOG4105ENH Sulfatase HHJ45_12090 ENOG4105C4X radical SAM domain protein HHJ45_12100 ENOG4105CQ0 ABC transporter HHJ45_12105 ENOG4105PE1 Receptor HHJ45_12110 ENOG4107RAN Peptidase, M16 HHJ45_12115 ENOG4105CVK Glutamate decarboxylase HHJ45_12120 ENOG4105E5D amino acid HHJ45_12125 ENOG4105F32 YngK protein HHJ45_12135 ENOG4105BZU Histidine kinase HHJ45_12140 ENOG4108UQS dipeptidase HHJ45_12145 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ45_12150 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ45_12155 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ45_12160 ENOG4105C3U ABC transporter HHJ45_12165 ENOG4107H6U ABC transporter HHJ45_12170 ENOG4108Z9K Osmotically inducible protein HHJ45_12175 ENOG4105TPS biofilm-dependent modulation protein HHJ45_12180 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HHJ45_12190 ENOG4105DQ4 alcohol dehydrogenase HHJ45_12195 ENOG41084S7 Plasmid maintenance system antidote protein HHJ45_12200 ENOG4108MG3 formate dehydrogenase HHJ45_12205 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ45_12215 ENOG4105RPH Inner membrane protein YddG HHJ45_12230 ENOG4107QND Nitrite extrusion protein HHJ45_12235 ENOG4105CRU nitrate reductase, alpha subunit HHJ45_12240 ENOG4108IUE nitrate reductase beta subunit HHJ45_12245 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HHJ45_12250 ENOG4105D0D Nitrate reductase 2, gamma subunit HHJ45_12255 ENOG4105JAB phenazine biosynthesis protein, phzf family HHJ45_12260 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HHJ45_12265 ENOG4108MEJ flavin reductase domain protein HHJ45_12285 ENOG4105CNA YD repeat protein HHJ45_12315 ENOG4105CNA YD repeat protein HHJ45_12335 ENOG4105C85 amino acid HHJ45_12340 ENOG4108NS2 receptor HHJ45_12345 ENOG4105CHB tonB-dependent Receptor HHJ45_12350 ENOG4108WYP Transcriptional regulator HHJ45_12355 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HHJ45_12360 ENOG4108Z7F N-acetyltransferase HHJ45_12365 ENOG4108T9Y Inner membrane protein ydcZ HHJ45_12370 ENOG4105R71 cytoplasmic protein HHJ45_12375 ENOG410654E Membrane HHJ45_12390 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HHJ45_12395 ENOG4105D81 ABC transporter, permease HHJ45_12415 ENOG4107TYH extracellular solute-binding protein family 1 HHJ45_12420 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ45_12425 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HHJ45_12435 ENOG4105RR0 Protein of unknown function (DUF2554) HHJ45_12440 ENOG4105CFP Peptidase U32 HHJ45_12445 ENOG4108JCI Transcriptional regulator HHJ45_12450 ENOG4105DKK Benzoate HHJ45_12455 ENOG4105D7V transposase HHJ45_12465 ENOG4108KKZ (LipO)protein HHJ45_12470 ENOG41088CC tellurite resistance protein tehB HHJ45_12475 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HHJ45_12480 ENOG4107WE3 acetyltransferase YdcK HHJ45_12485 ENOG4108Z9I -acetyltransferase HHJ45_12490 ENOG4105Z2P Protein of unknown function (DUF465) HHJ45_12500 ENOG4105E32 cytoplasmic protein HHJ45_12505 ENOG4105DDW LysR family Transcriptional regulator HHJ45_12510 ENOG4105C8Q Methyl-accepting chemotaxis HHJ45_12515 ENOG4107NK6 Hok/gef family HHJ45_12520 ENOG4105UPP uncharacterized protein ydcA HHJ45_12525 ENOG4105CPW cytochrome b561 HHJ45_12530 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ45_12535 ENOG4105C26 Dehydrogenase HHJ45_12540 ENOG4107DB1 DUF218 domain HHJ45_12545 ENOG4105CQ7 ATP-dependent helicase HHJ45_12555 ENOG41077RS Phosphatase HHJ45_12560 ENOG4105E8V Alpha Beta Hydrolase Fold protein HHJ45_12565 ENOG4108HPI phosphatidate Cytidylyltransferase HHJ45_12570 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HHJ45_12580 ENOG4107S5I aldo keto reductase HHJ45_12585 ENOG4108Z0R Transferase HHJ45_12590 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HHJ45_12595 ENOG4105DZS Phenylacetate-CoA ligase HHJ45_12600 ENOG4105CHU acetyl-coa acetyltransferase HHJ45_12605 ENOG4108ZJI phenylacetic acid degradation protein HHJ45_12610 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ45_12615 ENOG4108UKI Enoyl-CoA hydratase HHJ45_12620 ENOG4105E39 Enoyl-CoA hydratase HHJ45_12625 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ45_12630 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HHJ45_12635 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HHJ45_12640 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HHJ45_12645 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HHJ45_12650 ENOG4105DXM phenylacetic acid degradation protein HHJ45_12655 ENOG4105F11 amine oxidase HHJ45_12660 ENOG4105C26 Dehydrogenase HHJ45_12665 ENOG4108WFR AraC Family Transcriptional Regulator HHJ45_12670 ENOG4105WXT Conserved Protein HHJ45_12675 ENOG410689M (LipO)protein HHJ45_12680 ENOG4107H52 Dicarboxylate transport HHJ45_12685 ENOG4105C5I Dehydrogenase HHJ45_12690 ENOG41090X5 Heat shock protein hslJ HHJ45_12695 ENOG4105IKK cytoplasmic protein HHJ45_12700 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HHJ45_12710 ENOG4108RW8 Universal stress protein F HHJ45_12720 ENOG4105C1J atp-dependent rna helicase HHJ45_12730 ENOG4105BZU Histidine kinase HHJ45_12735 ENOG4108DG9 Smr protein MutS2 HHJ45_12740 ENOG4106KR7 LysR family Transcriptional regulator HHJ45_12745 ENOG4105CH2 amidohydrolase HHJ45_12750 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HHJ45_12755 ENOG4105CFC Transporter HHJ45_12760 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ45_12765 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HHJ45_12770 ENOG4105Q9Y Universal stress protein HHJ45_12775 ENOG4105S5I Membrane HHJ45_12780 ENOG4105D64 Mechanosensitive ion channel HHJ45_12785 ENOG4107QSI ABC, transporter HHJ45_12790 ENOG4105EQ2 LysR family Transcriptional regulator HHJ45_12795 ENOG4105ENX hydrolase HHJ45_12810 ENOG4105KXI murein peptide amidase A HHJ45_12815 ENOG4107S8C mandelate racemase muconate lactonizing HHJ45_12820 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HHJ45_12825 ENOG4108JU8 Transcriptional regulator HHJ45_12835 ENOG4105CM6 amino acid regulated cytosolic protein HHJ45_12840 ENOG4105FKQ transcriptional regulator HHJ45_12845 ENOG4107EFV Outer membrane protein G HHJ45_12850 ENOG4108IJ9 (ABC) transporter HHJ45_12855 ENOG4107URF beta-phospho-glucomutase HHJ45_12860 ENOG4105C71 hydrolase family 65, central catalytic HHJ45_12865 ENOG4105CK5 oxidoreductase HHJ45_12870 ENOG4107TYA transient receptor potential locus HHJ45_12875 ENOG4107RRD Dehydrogenase HHJ45_12880 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HHJ45_12885 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HHJ45_12890 ENOG4105WEM extracellular solute-binding protein HHJ45_12895 ENOG4107QW3 Sucrose phosphorylase HHJ45_12900 ENOG4105K8Z Phage shock protein HHJ45_12905 ENOG4105NNG Peripheral inner membrane phage-shock protein HHJ45_12910 ENOG4105FM1 phage shock protein C HHJ45_12915 ENOG4105YYT phage shock protein B HHJ45_12920 ENOG41087YS Phage shock protein A HHJ45_12925 ENOG4105E51 psp operon transcriptional activator HHJ45_12930 ENOG4108JPW Aminotransferase HHJ45_12935 ENOG4105CJP fad dependent oxidoreductase HHJ45_12940 ENOG4105C26 Dehydrogenase HHJ45_12945 ENOG4107VRI Transcriptional regulator HHJ45_12950 ENOG4108Z86 Glutamine amidotransferase HHJ45_12955 ENOG4105CFQ glutamine synthetase HHJ45_12965 ENOG4105CUB amino acid HHJ45_12970 ENOG4105N0E Protein of unknown function (DUF2543) HHJ45_12975 ENOG4108HIY periplasmic HHJ45_12980 ENOG4108I5W peptide transport system, permease protein HHJ45_12985 ENOG4108EU3 peptide transport system, permease HHJ45_12990 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HHJ45_12995 ENOG4108JQ2 peptide transport system atp-binding protein HHJ45_13000 ENOG4105WDY DNA (cytosine-5-)-methyltransferase HHJ45_13005 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HHJ45_13010 ENOG4105Q4T oxidoreductase HHJ45_13025 ENOG4105BZU Histidine kinase HHJ45_13030 ENOG410643D UPF0509 protein HHJ45_13035 ENOG4105N2W Transcriptional regulator HHJ45_13045 ENOG4108ZJT translation initiation factor, Sui1 HHJ45_13055 ENOG4105CFV Tetratricopeptide repeat protein HHJ45_13060 ENOG4105Q4A inner membrane protein yciS HHJ45_13065 ENOG4105EYK Phosphatidylglycerophosphatase B HHJ45_13075 ENOG4107QM5 aconitate hydratase HHJ45_13100 ENOG4107R11 Transcriptional regulator HHJ45_13105 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ45_13110 ENOG4105RKX Protein of unknown function (DUF2498) HHJ45_13115 ENOG4105ERU peptidase HHJ45_13120 ENOG4105UBK short-chain dehydrogenase reductase HHJ45_13125 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ45_13130 ENOG4105FE9 pseudouridine synthase HHJ45_13135 ENOG4107RTD sua5 ycio yrdc ywlc family protein HHJ45_13140 ENOG4105DB7 PHP domain protein HHJ45_13150 ENOG4105CRQ synthase (Component I) HHJ45_13155 ENOG4108EFP Anthranilate synthase component II HHJ45_13160 ENOG4105DK0 Indole-3-glycerol phosphate synthase HHJ45_13180 ENOG4108Z9Z response to DNA damage stimulus HHJ45_13185 ENOG4108N8X transition metal ion binding HHJ45_13190 ENOG4105EIF outer membrane protein W HHJ45_13210 ENOG4105NAU thioesterase Superfamily protein HHJ45_13215 ENOG410822N TonB family HHJ45_13220 ENOG4105K9H YciI-like protein HHJ45_13225 ENOG4107SVH Potassium channel protein HHJ45_13245 ENOG4108JQ7 (ABC) transporter HHJ45_13250 ENOG4105C3U ABC transporter HHJ45_13255 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ45_13260 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ45_13265 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ45_13275 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HHJ45_13280 ENOG4105C0A alcohol dehydrogenase HHJ45_13285 ENOG4107104 thymidine kinase HHJ45_13295 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ45_13300 ENOG4105I93 response regulator HHJ45_13305 ENOG4105D78 K07001 NTE family protein HHJ45_13310 ENOG4105K5B UPF0225 protein HHJ45_13315 ENOG4105CIY formyltetrahydrofolate deformylase HHJ45_13335 ENOG41076YT nitrate reductase, gamma subunit HHJ45_13340 ENOG4105R3A Nitrate reductase HHJ45_13345 ENOG4108IUE nitrate reductase beta subunit HHJ45_13350 ENOG4105CRU nitrate reductase, alpha subunit HHJ45_13355 ENOG4105DQQ Major facilitator superfamily MFS_1 HHJ45_13360 ENOG4105BZU Histidine kinase HHJ45_13365 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ45_13370 ENOG4105ID0 Putative invasin HHJ45_13375 ENOG41090EX DsrE family HHJ45_13380 ENOG4108NH8 Cation transport protein HHJ45_13385 ENOG4105WS7 Cation transport regulator HHJ45_13390 ENOG4105EWV Sodium calcium exchanger membrane region HHJ45_13415 ENOG41063JG Transcriptional regulator HHJ45_13420 ENOG4108YY7 Invasion gene expression up-regulator SirB HHJ45_13425 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HHJ45_13450 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HHJ45_13455 ENOG4105CHH sulfate transporter HHJ45_13460 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HHJ45_13470 ENOG4105C3G gtp-binding protein HHJ45_13475 ENOG4105I1J Autotransporter HHJ45_13480 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HHJ45_13485 ENOG4105CMT Dihydroxyacetone kinase HHJ45_13490 ENOG4108UTZ Dihydroxyacetone kinase HHJ45_13495 ENOG4105VDH Dihydroxyacetone kinase HHJ45_13515 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HHJ45_13525 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HHJ45_13535 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ45_13545 ENOG4105ED1 spovr family HHJ45_13560 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HHJ45_13565 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ45_13570 ENOG4105KT5 UmuD protein HHJ45_13575 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HHJ45_13585 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HHJ45_13595 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HHJ45_13600 ENOG4105S66 prophage protein HHJ45_13610 ENOG4107QMS site-determining protein HHJ45_13645 ENOG410658X HHJ45_13665 ENOG4105BZU Histidine kinase HHJ45_13680 ENOG41064WM Uncharacterized protein YcgX HHJ45_13695 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ45_13700 ENOG4108R99 pseudouridine synthase HHJ45_13720 ENOG4107QTF adenylosuccinate lyase HHJ45_13725 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ45_13730 ENOG4105IFJ Histidine kinase HHJ45_13735 ENOG4105EZE Cupin 4 family protein HHJ45_13745 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ45_13755 ENOG4105D38 putrescine abc transporter HHJ45_13760 ENOG4107RUE extracellular solute-binding protein family 1 HHJ45_13780 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HHJ45_13790 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ45_13795 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ45_13800 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ45_13805 ENOG4105IQC Inner membrane protein YcfT HHJ45_13810 ENOG4108JA2 transcriptioN-repair coupling factor HHJ45_13815 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ45_13820 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HHJ45_13825 ENOG4108IND Tetr family transcriptional regulator HHJ45_13830 ENOG4107MBR 17 kDa surface antigen HHJ45_13835 ENOG4105CEP NADH dehydrogenase HHJ45_13855 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HHJ45_13860 ENOG41090DQ Lipoprotein HHJ45_13865 ENOG4105K59 histidine triad (HIT) protein HHJ45_13870 ENOG4105CNM Receptor HHJ45_13875 ENOG4105CI1 PTS System HHJ45_13880 ENOG4105F8V Hydrolase, tatD family HHJ45_13885 ENOG4107QRG dna polymerase iii HHJ45_13895 ENOG4105HHA aminodeoxychorismate lyase HHJ45_13900 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HHJ45_13905 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ45_13910 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ45_13915 ENOG4105CHR reductase HHJ45_13920 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HHJ45_13940 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HHJ45_13945 ENOG4108UHJ MAF-like protein HHJ45_13950 ENOG4105EI2 Pseudouridine synthase HHJ45_13955 ENOG4107QQB Ribonuclease E HHJ45_13960 ENOG4105DTJ flagellar hook-associated protein HHJ45_13965 ENOG4105E1Q flagellar hook-associated protein HHJ45_13970 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HHJ45_13985 ENOG4105CGA flagellar basal-body rod protein FlgG HHJ45_13990 ENOG4108KPB Flagellar basal-body rod protein FlgF HHJ45_13995 ENOG4105BZE flagellar hook protein, FlgE HHJ45_14000 ENOG4105W00 Flagellar hook capping protein HHJ45_14005 ENOG4108ZC9 flagellar basal-body rod protein flgc HHJ45_14010 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HHJ45_14015 ENOG4105CKS Flagella basal body P-ring formation protein flgA HHJ45_14020 ENOG4105M9M anti-sigma28 factor FlgM HHJ45_14025 ENOG4105QVD Flagella synthesis protein FlgN HHJ45_14030 ENOG4105CJR Integral membrane protein (MviN HHJ45_14035 ENOG4105EP9 oxidoreductase HHJ45_14045 ENOG4105D9U N-acetyltransferase HHJ45_14055 ENOG4105E9S glutaredoxin 2 HHJ45_14060 ENOG4105F3T (LipO)protein HHJ45_14065 ENOG4105EKE dihydroorotase HHJ45_14070 ENOG4105MEA DNA damage-inducible protein i HHJ45_14075 ENOG4105PVA Biofilm formation regulatory protein BssS HHJ45_14085 ENOG4106974 biofilm formation HHJ45_14090 ENOG4105DS1 cytochrome b561 HHJ45_14095 ENOG4108YYC ycei family HHJ45_14105 ENOG4105D1S lipid A biosynthesis HHJ45_14115 ENOG4108W47 Acidic protein msyB HHJ45_14120 ENOG4105NAC (LipO)protein HHJ45_14125 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HHJ45_14140 ENOG4107RZC phospholipase d HHJ45_14145 ENOG4108UVJ appr-1-p processing domain protein HHJ45_14160 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HHJ45_14165 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HHJ45_14170 ENOG41086KC Transcriptional regulator HHJ45_14175 ENOG4108XDW curli assembly protein CsgE HHJ45_14180 ENOG4108WYR Curli production assembly transport component, CsgF HHJ45_14185 ENOG4105P8Q Curli production assembly transport component CsgG HHJ45_14190 ENOG4108UQ5 membrane protein YcdZ HHJ45_14195 ENOG4107XHZ cytoplasmic chaperone TorD family protein HHJ45_14205 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HHJ45_14215 ENOG4108T85 Membrane HHJ45_14235 ENOG4108TUY outer membrane protein PgaA HHJ45_14240 ENOG4107BJW polysaccharide deacetylase HHJ45_14245 ENOG4105CND Glycosyl transferase, family 2 HHJ45_14255 ENOG4105D5M phosphate starvation-inducible protein HHJ45_14265 ENOG410650H (LipO)protein HHJ45_14275 ENOG4105CK7 Sodium proline symporter HHJ45_14285 ENOG4105C26 Dehydrogenase HHJ45_14290 ENOG4108R86 Transcriptional regulator HHJ45_14325 ENOG4105C2W permease HHJ45_14330 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HHJ45_14340 ENOG4105XH3 HHJ45_14345 ENOG4105D6F Phosphatase HHJ45_14370 ENOG4107QY8 reductase HHJ45_14375 ENOG4105CUW cytochrome C-TYPE protein HHJ45_14380 ENOG4106WF9 DNA-binding transcriptional regulator TorR HHJ45_14385 ENOG4108SV3 Tmao reductase system periplasmic protein tort HHJ45_14390 ENOG4105BZU Histidine kinase HHJ45_14395 ENOG4105HEE Binding Domain protein HHJ45_14400 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HHJ45_14415 ENOG4105VEQ Cold shock protein HHJ45_14420 ENOG41060EU Cold shock-like protein HHJ45_14430 ENOG4108Y9B (LipO)protein HHJ45_14435 ENOG4108W78 Pfam:DUF1017 HHJ45_14440 ENOG4105E3R (LipO)protein HHJ45_14445 ENOG4105DAY polysaccharide export protein HHJ45_14450 ENOG4107ZF2 Phosphatase HHJ45_14455 ENOG4105D75 Capsular exopolysaccharide family HHJ45_14460 ENOG4105D6F Phosphatase HHJ45_14470 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ45_14475 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ45_14480 ENOG4105MVP hydrogenase-1 operon protein HyaF HHJ45_14485 ENOG4108VXY Hydrogenase-1 operon protein HyaE HHJ45_14490 ENOG4108USZ hydrogenase HHJ45_14495 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HHJ45_14500 ENOG4105DPX Hydrogenase, large subunit HHJ45_14505 ENOG4105E3S small subunit HHJ45_14515 ENOG4108MN8 Membrane HHJ45_14520 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HHJ45_14525 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HHJ45_14540 ENOG4105K4P CoA-binding domain protein HHJ45_14555 ENOG41088T4 Helicase IV HHJ45_14560 ENOG410901E Membrane HHJ45_14565 ENOG4105EM2 membrane HHJ45_14570 ENOG4108RZ1 DNA transformation protein HHJ45_14580 ENOG4105UYK outer membrane protein a HHJ45_14590 ENOG4105DAN ATP-dependent protease HHJ45_14600 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HHJ45_14605 ENOG4108Q2G (LipO)protein HHJ45_14610 ENOG4105DY2 Paraquat-inducible protein b HHJ45_14615 ENOG4105F1S paraquat-inducible protein a HHJ45_14620 ENOG4105C5H ABC transporter HHJ45_14630 ENOG4105QVC MOSC domain-containing protein HHJ45_14635 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HHJ45_14645 ENOG4106PH7 chaperone HHJ45_14650 ENOG4105MX3 Fimbrial HHJ45_14655 ENOG4105Q7J Fimbrial HHJ45_14660 ENOG4108MDY Fimbrial HHJ45_14665 ENOG4105CW0 outer membrane usher protein HHJ45_14670 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HHJ45_14675 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HHJ45_14680 ENOG4108UZX fmn reductase HHJ45_14685 ENOG4105GVF (ABC) transporter HHJ45_14695 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HHJ45_14705 ENOG4105CD8 aminopeptidase N HHJ45_14720 ENOG4105FCK Membrane HHJ45_14725 ENOG4105CGF Aromatic amino acid aminotransferase HHJ45_14735 ENOG4105C5X domain protein HHJ45_14740 ENOG4105EAQ (twin-arginine translocation) pathway signal HHJ45_14745 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HHJ45_14755 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HHJ45_14765 ENOG4106371 Methyltransferase HHJ45_14770 ENOG4107S90 membrAne HHJ45_14775 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HHJ45_14790 ENOG4105T0Z Conserved Protein HHJ45_14800 ENOG4105BZ1 (ABC) transporter HHJ45_14805 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HHJ45_14815 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HHJ45_14825 ENOG4108K0D peptidase, M48 HHJ45_14840 ENOG4107VMU Membrane HHJ45_14845 ENOG4105DDY UPF0142 protein ycaO HHJ45_14850 ENOG4105TMB Formate nitrite transporter HHJ45_14855 ENOG4105C6N Formate acetyltransferase HHJ45_14860 ENOG4105F1A Pyruvate formate-lyase HHJ45_14865 ENOG4108X0B nad(p)h dehydrogenase (quinone) HHJ45_14870 ENOG410642W LysR family Transcriptional regulator HHJ45_14875 ENOG4105E5D amino acid HHJ45_14885 ENOG4105CHJ isochorismatase hydrolase HHJ45_14890 ENOG4107KGK dmso reductase anchor subunit HHJ45_14895 ENOG4105QAX Iron-sulfur HHJ45_14900 ENOG4107QY8 reductase HHJ45_14910 ENOG4105D1H recombination factor protein RarA HHJ45_14920 ENOG4105CNU cell division protein FtsK HHJ45_14930 ENOG4105C3M thioredoxin reductase HHJ45_14935 ENOG4108JJ9 ABC, transporter HHJ45_14940 ENOG4108JJ8 (ABC) transporter HHJ45_14950 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HHJ45_14980 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ45_14995 ENOG4108YGG dna repair protein HHJ45_15000 ENOG4105MFG Antirestriction protein HHJ45_15005 ENOG4106H6R UPF0380 protein HHJ45_15020 ENOG4108PZQ Inner membrane protein YeeR HHJ45_15025 ENOG4105F4K antigen 43 HHJ45_15110 ENOG4108SF5 RNA Polymerase HHJ45_15115 ENOG4108S3W Anti-feci sigma factor, fecr HHJ45_15120 ENOG4105GAV receptor HHJ45_15125 ENOG4108HUF Transporter HHJ45_15130 ENOG4105DQ5 transport system permease protein HHJ45_15135 ENOG4108IHU transport system permease protein HHJ45_15140 ENOG4105E0A ABC, transporter HHJ45_15165 ENOG4107BJW polysaccharide deacetylase HHJ45_15170 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) HHJ45_15175 ENOG4108MJ5 VirK protein HHJ45_15180 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ45_15190 ENOG4105C94 Transporter HHJ45_15210 ENOG4105D5Q Arginine ornithine antiporter HHJ45_15215 ENOG4105CXN decarboxylase HHJ45_15220 ENOG4105D5Q Arginine ornithine antiporter HHJ45_15235 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ45_15245 ENOG4107YNJ LysR family Transcriptional regulator HHJ45_15275 ENOG4105EDR glucose galactose transporter HHJ45_15285 ENOG4107FB0 transcriptional regulator DeoR family HHJ45_15300 ENOG4105CTX dehydratase HHJ45_15305 ENOG4105CTX dehydratase HHJ45_15310 ENOG4105E98 transcriptional regulator DeoR family HHJ45_15315 ENOG4105D2N Aldolase HHJ45_15320 ENOG4105CI1 PTS System HHJ45_15325 ENOG4105C87 Aminotransferase class I and II HHJ45_15335 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ45_15360 ENOG4108P8R HHJ45_15390 ENOG4105DFP Integrase HHJ45_15395 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ45_15405 ENOG4105VEQ Cold shock protein HHJ45_15410 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ45_15415 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ45_15420 ENOG4108MJ5 VirK protein HHJ45_15425 ENOG4105CPB ATP-dependent endonuclease of the OLD family HHJ45_15430 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ45_15435 ENOG4105DWU Membrane HHJ45_15445 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ45_15450 ENOG4105C7K acetolactate synthase HHJ45_15455 ENOG4105C5W Aldolase HHJ45_15465 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HHJ45_15470 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ45_15480 ENOG41064MM (LipO)protein HHJ45_15485 ENOG4105E5Z arginine transporter ATP-binding subunit HHJ45_15490 ENOG4106PMH Extracellular solute-binding protein family 3 HHJ45_15495 ENOG4105GBT ABC transporter HHJ45_15500 ENOG4105DMR ABC, transporter HHJ45_15505 ENOG4106TNF Periplasmic binding protein HHJ45_15515 ENOG4105RBQ inner membrane protein ybjO HHJ45_15520 ENOG4105D38 putrescine abc transporter HHJ45_15525 ENOG4105F38 ABC transporter, permease HHJ45_15530 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ45_15535 ENOG4107RUE extracellular solute-binding protein family 1 HHJ45_15540 ENOG4108RMJ sensory transduction regulator HHJ45_15565 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HHJ45_15570 ENOG41090BQ Glutaredoxin HHJ45_15575 ENOG4105GWF inner membrane protein YbjM HHJ45_15585 ENOG4108RFG Tetr family transcriptional regulator HHJ45_15590 ENOG4106UW1 Major Facilitator superfamily HHJ45_15595 ENOG4108HCJ Hydrolase HHJ45_15605 ENOG4107QF7 multi-drug HHJ45_15610 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HHJ45_15615 ENOG4107FB0 transcriptional regulator DeoR family HHJ45_15620 ENOG4105DZ1 carboxypeptidase HHJ45_15625 ENOG4108TGY Glutathione S-transferase HHJ45_15630 ENOG4105D8V Glucose sorbosone dehydrogenase HHJ45_15635 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HHJ45_15645 ENOG41064RH membrane protein YliF HHJ45_15675 ENOG4105D44 asparaginase HHJ45_15680 ENOG4105CVM Molybdenum cofactor synthesis domain protein HHJ45_15685 ENOG4105D06 uba thif-type nad fad binding protein HHJ45_15690 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ45_15695 ENOG4105F1A Pyruvate formate-lyase HHJ45_15705 ENOG4108HCJ Hydrolase HHJ45_15710 ENOG41072TH Protein of unknown function (DUF1479) HHJ45_15720 ENOG4105C5H ABC transporter HHJ45_15725 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ45_15730 ENOG4105F4P )-transporter HHJ45_15735 ENOG4105KST dependent repressor HHJ45_15745 ENOG4108I6E Sulfatase HHJ45_15750 ENOG4108T1M outer membrane protein x HHJ45_15760 ENOG4107AQZ Membrane HHJ45_15770 ENOG4107R0W ABC transporter HHJ45_15775 ENOG4105E5Q amino acid AbC transporter HHJ45_15780 ENOG4105CDA abc transporter atp-binding protein HHJ45_15785 ENOG4105D8X mechanosensitive ion channel HHJ45_15795 ENOG4105ZY9 UPF0379 protein ybiM HHJ45_15800 ENOG4108IU3 tonb-dependent siderophore receptor HHJ45_15810 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ45_15815 ENOG4105VR4 UPF0379 protein ybiJ HHJ45_15825 ENOG4105DG4 malate L-lactate dehydrogenase HHJ45_15830 ENOG4108MTB glycosyl transferase family HHJ45_15835 ENOG4105DVT helicase HHJ45_15840 ENOG4108UV1 cellular component movement HHJ45_15845 ENOG4105C1J atp-dependent rna helicase HHJ45_15850 ENOG4107MVR Transcriptional regulator HHJ45_15860 ENOG4105CJ1 ABC, transporter HHJ45_15865 ENOG4107QWP ABC-2 type transporter HHJ45_15870 ENOG4107QWP ABC-2 type transporter HHJ45_15875 ENOG4105I9U inner membrane protein ybhQ HHJ45_15880 ENOG4105X23 Endonuclease Exonuclease phosphatase HHJ45_15885 ENOG4105DZQ phospholipase D Transphosphatidylase HHJ45_15890 ENOG4107UXM Membrane HHJ45_15895 ENOG410733J conserved inner membrane protein HHJ45_15905 ENOG4105HFZ Membrane HHJ45_15910 ENOG4108ZAF Molybdopterin HHJ45_15915 ENOG4105M00 molybdopterin converting factor, subunit 1 HHJ45_15925 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ45_15935 ENOG4105CHW UPF0052 protein HHJ45_15945 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ45_15950 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HHJ45_15965 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HHJ45_15970 ENOG4108V1U phospholipid-binding protein HHJ45_15975 ENOG4105NBR Pectinesterase HHJ45_15980 ENOG4107QM5 aconitate hydratase HHJ45_15985 ENOG4107QPK )-transporter HHJ45_15990 ENOG4105C7F AcnD-accessory protein PrpF HHJ45_15995 ENOG4105F04 LysR family Transcriptional regulator HHJ45_16005 ENOG4108K4B hydrolase HHJ45_16015 ENOG4105E0C molybdate abc transporter HHJ45_16020 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HHJ45_16030 ENOG4105F4R Transcriptional regulator mode HHJ45_16035 ENOG4105DKW ABC transporter HHJ45_16040 ENOG4105CMR udp-glucose 4-epimerase HHJ45_16045 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HHJ45_16055 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HHJ45_16065 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ45_16070 ENOG4105JND homeobox protein HHJ45_16075 ENOG4105PGM cation diffusion facilitator family transporter HHJ45_16080 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ45_16130 ENOG4105UFD tol-pal system protein YbgF HHJ45_16135 ENOG4105KCK Peptidoglycan-associated lipoprotein HHJ45_16145 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HHJ45_16155 ENOG4105E02 MotA TolQ exbB proton channel HHJ45_16160 ENOG4107YD3 Thioesterase HHJ45_16165 ENOG4105KJB cyd operon protein YbgE HHJ45_16175 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ45_16180 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ45_16190 ENOG4105C8I hydrolase, family 38 HHJ45_16195 ENOG4105DM4 PTS System HHJ45_16200 ENOG4105FDP GntR family transcriptional regulator HHJ45_16205 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ45_16215 ENOG4105C7S Dehydrogenase HHJ45_16220 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ45_16225 ENOG4105E33 succinate dehydrogenase HHJ45_16230 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ45_16235 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HHJ45_16240 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HHJ45_16250 ENOG4105BZN citrate synthase HHJ45_16260 ENOG4106PG1 outer membrane usher protein HHJ45_16265 ENOG4108TTM chaperone HHJ45_16270 ENOG4108MY7 Fimbrial HHJ45_16275 ENOG4108KK1 membrane protein AbrB duplication HHJ45_16285 ENOG4105E7W lamb ycsf family protein HHJ45_16290 ENOG4107R7A Allophanate hydrolase subunit 2 HHJ45_16295 ENOG4105P4J Allophanate hydrolase, subunit 1 HHJ45_16300 ENOG4107QNR UPF0135 protein HHJ45_16305 ENOG4105DUX Transporter HHJ45_16310 ENOG4105CVP deoxyribo-dipyrimidine photolyase HHJ45_16315 ENOG4107SEY Conserved Protein HHJ45_16330 ENOG4106R09 HHJ45_16335 ENOG4105CNA YD repeat protein HHJ45_16360 ENOG4105XIQ Protein of unknown function (DUF2517) HHJ45_16385 ENOG4105C08 Histidine kinase HHJ45_16390 ENOG4105EEX Two component transcriptional regulator (Winged helix family HHJ45_16405 ENOG4105CXN decarboxylase HHJ45_16410 ENOG4105D5Q Arginine ornithine antiporter HHJ45_16415 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HHJ45_16420 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HHJ45_16425 ENOG4105EV9 Alpha Beta Hydrolase HHJ45_16430 ENOG4105NNH LexA regulated protein HHJ45_16435 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HHJ45_16445 ENOG41090R7 Ferric uptake HHJ45_16450 ENOG4105GX6 (LipO)protein HHJ45_16465 ENOG4105CI1 PTS System HHJ45_16475 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ45_16480 ENOG4105E2R ROK family HHJ45_16485 ENOG4105D4U had-superfamily hydrolase, subfamily iia HHJ45_16490 ENOG4105CAQ asparagine synthetase HHJ45_16530 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ45_16540 ENOG4105C9A Phoh family HHJ45_16550 ENOG4108JU5 Magnesium and cobalt efflux protein HHJ45_16555 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HHJ45_16560 ENOG4107U91 Rhomboid family HHJ45_16565 ENOG4107RP9 extracellular solute-binding protein, family 3 HHJ45_16570 ENOG4105EAD ABC transporter HHJ45_16575 ENOG4105DRP amino acid AbC transporter HHJ45_16580 ENOG4105CDA abc transporter atp-binding protein HHJ45_16590 ENOG4105F7F Chaperone HHJ45_16595 ENOG4105QFC Hsc56 co-chaperone of HscC HHJ45_16610 ENOG4105QFC Hsc56 co-chaperone of HscC HHJ45_16615 ENOG41069CF Protein of unknown function (DUF1266) HHJ45_16620 ENOG4105EUU Sel1 domain protein repeat-containing protein HHJ45_16625 ENOG4107PAI alpha helical protein HHJ45_16640 ENOG4105DJF DNA polymerase III, delta' subunit HHJ45_16650 ENOG4108TGR phosphatase HHJ45_16655 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HHJ45_16665 ENOG4105CJN penicillin-binding protein HHJ45_16670 ENOG4105CNI cell division protein FtsW HHJ45_16675 ENOG4105K6T rare lipoprotein A HHJ45_16680 ENOG4105DZ1 carboxypeptidase HHJ45_16695 ENOG41064T2 transcriptional regulator, lysR family HHJ45_16705 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HHJ45_16730 ENOG4105CEE C4-dicarboxylate transporter HHJ45_16735 ENOG4106YYS transcriptional regulatory protein HHJ45_16740 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ45_16745 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ45_16755 ENOG4105CI0 Citrate lyase HHJ45_16760 ENOG4105CHY citrate lyase, alpha HHJ45_16775 ENOG4107QPK )-transporter HHJ45_16780 ENOG4105KTS ribonuclease HHJ45_16785 ENOG4105NXH GreA GreB family elongation factor HHJ45_16790 ENOG4105E2A Dehydrogenase HHJ45_16795 ENOG4108U51 Universal stress protein HHJ45_16800 ENOG4108JU3 Alkyl hydroperoxide reductase HHJ45_16805 ENOG4105D3R alkyl hydroperoxide reductase HHJ45_16810 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HHJ45_16815 ENOG4105DQS Transcriptional regulator HHJ45_16820 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ45_16825 ENOG4105GTN ParB Domain Protein Nuclease HHJ45_16830 ENOG4105CHM Aminotransferase HHJ45_16835 ENOG4107SCQ Iron-containing alcohol dehydrogenase HHJ45_16840 ENOG4105VCD cytoplasmic protein HHJ45_16845 ENOG4105D22 carbon starvation protein HHJ45_16850 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HHJ45_16855 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HHJ45_16860 ENOG4105WQI isochorismatase HHJ45_16865 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ45_16870 ENOG4105E4F Isochorismate synthase HHJ45_16875 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HHJ45_16885 ENOG4105DQ5 transport system permease protein HHJ45_16890 ENOG4105TVJ transport system, permease HHJ45_16895 ENOG4105E0A ABC, transporter HHJ45_16900 ENOG4108QY5 Ferric enterobactin transport protein HHJ45_16905 ENOG4105C0W non-ribosomal peptide synthetase HHJ45_16910 ENOG41085A6 mbth domain-containing protein HHJ45_16915 ENOG4105E93 esterase HHJ45_16920 ENOG4107RNH Outer membrane receptor FepA HHJ45_16925 ENOG4108TSE Transferase HHJ45_16935 ENOG4107635 Hok Gef family protein HHJ45_16945 ENOG4105WQ6 Membrane HHJ45_16950 ENOG4105MSB protein, conserved in bacteria HHJ45_16955 ENOG4108RCM Nitroreductase HHJ45_16960 ENOG4105CUY Mechanosensitive ion channel HHJ45_16965 ENOG4105C85 amino acid HHJ45_16970 ENOG4108IJF Heavy metal efflux pump, CzcA HHJ45_16975 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HHJ45_16980 ENOG410624V efflux system protein HHJ45_16985 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ45_16990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ45_16995 ENOG4105GR3 Histidine kinase HHJ45_17005 ENOG4105CS6 Rhs element vgr protein HHJ45_17040 ENOG410802X bacteriophage n4 adsorption protein b HHJ45_17045 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HHJ45_17050 ENOG4105QUW HHJ45_17060 ENOG4108NC2 Outer membrane protease HHJ45_17085 ENOG4105W3V DNA-binding, transcriptional regulator HHJ45_17090 ENOG4105MN3 Resolvase HHJ45_17095 ENOG4105UZW Tail fiber assembly protein HHJ45_17100 ENOG4108X9F tail fiber protein HHJ45_17175 ENOG4105IM0 capsid protein HHJ45_17185 ENOG4105F7J membrane-bound serine protease HHJ45_17195 ENOG4107DE1 head-to-tail joining protein HHJ45_17200 ENOG4105UZW Tail fiber assembly protein HHJ45_17205 ENOG4105FKG DNA packaging protein HHJ45_17210 ENOG4106YSC HHJ45_17215 ENOG4105QYK bacteriophage lambda Bor protein homolog HHJ45_17225 ENOG4105KUS lysozyme HHJ45_17230 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ45_17240 ENOG4105HRS Antitermination protein HHJ45_17255 ENOG4105RWQ Protein of unknown function (DUF1364) HHJ45_17260 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 HHJ45_17265 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi HHJ45_17370 ENOG4108KU3 Integrase HHJ45_17380 ENOG4108Q9V regulatoR HHJ45_17385 ENOG4108ZI2 Fimbrial protein HHJ45_17390 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HHJ45_17395 ENOG4105CW0 outer membrane usher protein HHJ45_17400 ENOG4108AF8 Chaperone HHJ45_17405 ENOG4108WDE Fimbrial protein HHJ45_17415 ENOG4105WQ3 Rna-binding protein HHJ45_17420 ENOG4105S2T inner membrane protein YbcI HHJ45_17430 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ45_17440 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HHJ45_17445 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HHJ45_17450 ENOG4105C5B carbamate kinase HHJ45_17455 ENOG4105G5A Protein of unknown function (DUF2877) HHJ45_17460 ENOG4107REC cytoplasmic protein HHJ45_17465 ENOG4107R1Q Membrane protein FdrA HHJ45_17470 ENOG4105DG4 malate L-lactate dehydrogenase HHJ45_17475 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HHJ45_17480 ENOG4105S0E allantoin catabolism protein HHJ45_17485 ENOG4105BZW Glycerate kinase HHJ45_17490 ENOG4105DTE Xanthine uracil vitamin C permease HHJ45_17500 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HHJ45_17505 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ45_17510 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ45_17515 ENOG41060W2 glyoxylate carboligase HHJ45_17520 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HHJ45_17530 ENOG4107653 Transcriptional regulator HHJ45_17540 ENOG4105CV6 ABC transporter, permease HHJ45_17545 ENOG4108I0Y (ABC) transporter HHJ45_17550 ENOG4108UJV acyl-CoA thioesterase i HHJ45_17555 ENOG4105E1F short-chain dehydrogenase reductase HHJ45_17560 ENOG4107QR8 Thioredoxin HHJ45_17565 ENOG4105C4B ABC transporter, permease HHJ45_17570 ENOG41083J0 (ABC) transporter HHJ45_17575 ENOG4107QX8 SPFH domain, Band 7 family protein HHJ45_17580 ENOG4105G5H Membrane HHJ45_17585 ENOG4108Z6Z Transcriptional regulator HHJ45_17590 ENOG4107RY6 amino acid HHJ45_17595 ENOG4105CSV Glutaminase HHJ45_17600 ENOG4105C59 p-type ATPase HHJ45_17605 ENOG41081XE plasmid maintenance system antidote protein, xre family HHJ45_17610 ENOG4105MBR gumn family HHJ45_17615 ENOG4108Z66 YbaK ebsC protein HHJ45_17620 ENOG4105CGH 5'-nucleotidase HHJ45_17625 ENOG4105EU0 Major facilitator Superfamily HHJ45_17630 ENOG4105CKD glutathione-regulated potassium-efflux system protein HHJ45_17635 ENOG4107RE1 Inosine-guanosine kinase HHJ45_17670 ENOG4107QMP dna polymerase iii subunits gamma and tau HHJ45_17680 ENOG4105WD1 Membrane HHJ45_17685 ENOG4108URS primosomal replication protein n'' HHJ45_17690 ENOG4106428 Protein of unknown function (DUF2496) HHJ45_17695 ENOG4105EGS Mechanosensitive ion channel HHJ45_17700 ENOG4107XI7 Tetr family transcriptional regulator HHJ45_17705 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ45_17710 ENOG4105BZS acriflavin resistance protein HHJ45_17715 ENOG4108UKR Biofilm formation regulator YbaJ HHJ45_17720 ENOG4105KF5 hemolysin expression-modulating protein HHJ45_17725 ENOG4108UW5 maltose o-acetyltransferase HHJ45_17730 ENOG4105GSJ Inner membrane protein ylaC HHJ45_17735 ENOG41066DG (EAL) domain protein HHJ45_17740 ENOG4105KCV RNA signal recognition particle 4.5S RNA HHJ45_17750 ENOG41080UX Methyltransferase HHJ45_17755 ENOG4108MNP Glycoprotein polysaccharide metabolism HHJ45_17760 ENOG4105C29 acyl-CoA thioesterase HHJ45_17765 ENOG4105BZU Histidine kinase HHJ45_17770 ENOG4108YZA Nitrogen regulatory protein pii HHJ45_17775 ENOG4105BZ1 (ABC) transporter HHJ45_17780 ENOG4105BZ1 (ABC) transporter HHJ45_17785 ENOG4108XM1 transcriptional regulator AsnC family HHJ45_17795 ENOG4108NFA extracellular solute-binding protein HHJ45_17805 ENOG4108TGP Thioesterase superfamily protein HHJ45_17810 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HHJ45_17815 ENOG4105EIN peptidylprolyl cis-trans isomerase HHJ45_17820 ENOG4105K70 DNA-binding protein HHJ45_17825 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HHJ45_17845 ENOG4105M85 Bola protein HHJ45_17850 ENOG4105IEY (LipO)protein HHJ45_17855 ENOG4105EYM Major Facilitator superfamily HHJ45_17860 ENOG4105E2S oxidase) subunit II HHJ45_17865 ENOG4105BZ9 Cytochrome C oxidase, subunit I HHJ45_17870 ENOG4105CCU oxidase (Subunit III) HHJ45_17875 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HHJ45_17900 ENOG4107RDB Major Facilitator HHJ45_17910 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HHJ45_17915 ENOG4107S0N DJ-1 family HHJ45_17930 ENOG4105CTB Polyprenyl synthetase HHJ45_17940 ENOG4105CPC Aldo Keto reductase HHJ45_17945 ENOG4108ZAI phosphatidylglycerophosphatase a HHJ45_17950 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HHJ45_17960 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HHJ45_17965 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HHJ45_17975 ENOG4108KIC (LipO)protein HHJ45_17980 ENOG4105DRB nucleoside-specific channel-forming protein HHJ45_17985 ENOG4105N1F Hnh endonuclease HHJ45_17990 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ45_17995 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ45_18000 ENOG4105VIE preprotein translocase, subunit YajC HHJ45_18025 ENOG4105C85 amino acid HHJ45_18030 ENOG4105CWM branched-chain amino acid transport system II carrier protein HHJ45_18035 ENOG4105BZU Histidine kinase HHJ45_18040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ45_18045 ENOG4107RH8 nuclease SbcCD subunit D HHJ45_18050 ENOG4105EYH Exonuclease HHJ45_18055 ENOG4105F27 Major Facilitator HHJ45_18060 ENOG4105DKQ ROK family HHJ45_18080 ENOG4105HBA AroM protein HHJ45_18085 ENOG4105SS3 HHJ45_18100 ENOG4105II7 pyrroline-5-carboxylate reductase HHJ45_18105 ENOG4105BZU Histidine kinase HHJ45_18110 ENOG4105VIF phosphate starvation-inducible protein HHJ45_18115 ENOG4105G6Z alkaline phosphatase HHJ45_18130 ENOG4105CPF Cell wall formation (By similarity) HHJ45_18135 ENOG4105UNH Membrane HHJ45_18140 ENOG4105FR5 inner membrane protein YaiY HHJ45_18145 ENOG4107QS8 (LipO)protein HHJ45_18150 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HHJ45_18155 ENOG4107R6D beta-lactam binding protein AmpH HHJ45_18160 ENOG4108PNB DNA-binding transcriptional regulator HHJ45_18170 ENOG4105D52 delta-aminolevulinic acid dehydratase HHJ45_18175 ENOG4105E2B Taurine dioxygenase HHJ45_18180 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HHJ45_18190 ENOG4106FTQ Taurine ABC transporter, periplasmic HHJ45_18195 ENOG4107W19 lmbE family HHJ45_18200 ENOG4108PBI Polysaccharide metabolism HHJ45_18210 ENOG4105SRB Uncharacterized protein yaiO HHJ45_18230 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HHJ45_18235 ENOG4108SC4 )-transporter HHJ45_18270 ENOG4108K2P TRANSCRIPTIONal HHJ45_18275 ENOG4105ETE Transcriptional regulator (LacI family HHJ45_18280 ENOG4105CNT hydrolase family 2 HHJ45_18285 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ45_18290 ENOG4108UW5 maltose o-acetyltransferase HHJ45_18300 ENOG4105DJ2 Major Facilitator Superfamily HHJ45_18310 ENOG4107B2H carbonic anhydrase HHJ45_18315 ENOG4105DND Transcriptional regulator HHJ45_18320 ENOG4105DZC cytosine deaminase HHJ45_18325 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ45_18330 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ45_18335 ENOG4105DXD 2-methylcitrate dehydratase HHJ45_18340 ENOG4105BZN citrate synthase HHJ45_18345 ENOG4105CR4 methylisocitrate lyase HHJ45_18350 ENOG4108JU7 Transcriptional regulator HHJ45_18355 ENOG4105TDT uncharacterized protein yahO HHJ45_18360 ENOG4105E82 cytochrome subunit of dehydrogenase HHJ45_18375 ENOG4105DQ4 alcohol dehydrogenase HHJ45_18380 ENOG4105CNN ABC, transporter HHJ45_18385 ENOG4105CNN ABC, transporter HHJ45_18390 ENOG4105C2J ABC transporter HHJ45_18395 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ45_18405 ENOG4105DZC cytosine deaminase HHJ45_18410 ENOG4105C5B carbamate kinase HHJ45_18415 ENOG4107REC cytoplasmic protein HHJ45_18420 ENOG4107R1Q Membrane protein FdrA HHJ45_18425 ENOG4105N16 Protein of unknown function (DUF2877) HHJ45_18430 ENOG4107SNB ankyrin repeat protein YahD HHJ45_18435 ENOG4105SZ2 membrAne HHJ45_18440 ENOG4108NUU Transcriptional regulator HHJ45_18445 ENOG4105BZU Histidine kinase HHJ45_18455 ENOG4105C94 Transporter HHJ45_18495 ENOG4105BZU Histidine kinase HHJ45_18525 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HHJ45_18530 ENOG4107QR9 Iron-sulfur cluster binding protein HHJ45_18535 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ45_18540 ENOG4108K01 transcriptional regulator HHJ45_18545 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ45_18550 ENOG41066GK UPF0379 protein ykgI HHJ45_18555 ENOG4108KBJ Inner membrane protein YkgB HHJ45_18605 ENOG4108N3D putative enzyme HHJ45_18610 ENOG4106PYX Receptor HHJ45_18615 ENOG4108UD7 cell wall organization HHJ45_18620 ENOG4105PI0 Ferredoxin HHJ45_18625 ENOG4105R3P Inner membrane protein yagU HHJ45_18630 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HHJ45_18635 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding HHJ45_18645 ENOG4107XAN XdhC and CoxI family HHJ45_18670 ENOG4105FCK Membrane HHJ45_18690 ENOG4105CIN aminoacyl-histidine dipeptidase HHJ45_18695 ENOG4108S2Y peptide Chain Release factor HHJ45_18705 ENOG4108HYG acetyltransferase HHJ45_18735 ENOG4108YS0 lipoprotein YafL HHJ45_18745 ENOG4105VXN addiction module toxin, RelE StbE family HHJ45_18750 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HHJ45_18755 ENOG4105E7A Glutamine amidotransferase HHJ45_18765 ENOG4107QPN acyl-Coa dehydrogenase HHJ45_18770 ENOG4108WN0 inhibitor of vertebrate lysozyme HHJ45_18775 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ45_18820 ENOG4105CNA YD repeat protein HHJ45_18825 ENOG4105CS6 Rhs element vgr protein HHJ45_18830 ENOG4108WC9 type VI secretion system effector, hcp1 family HHJ45_18885 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ45_18910 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ45_18925 ENOG410600K aminopeptidase HHJ45_18935 ENOG4107RZZ dna polymerase iii epsilon subunit HHJ45_18945 ENOG4105D1A Methyltransferase HHJ45_18955 ENOG4105E9H Lytic Murein transglycosylase HHJ45_18960 ENOG4105F2W methyltransferase HHJ45_18970 ENOG4105HEI LysR family (Transcriptional regulator HHJ45_18975 ENOG4105CV8 reductase HHJ45_19010 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HHJ45_19015 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HHJ45_19020 ENOG4108UMI ABC transporter, permease HHJ45_19025 ENOG4105D01 (LipO)protein HHJ45_19030 ENOG4108R8X outer membrane lipoprotein HHJ45_19035 ENOG4108R96 Methyltransferase, YaeB family HHJ45_19055 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HHJ45_19060 ENOG4108YZN class I peptide chain release factor HHJ45_19065 ENOG4108VWS Yaeq family HHJ45_19075 ENOG4105M1T rho-binding antiterminator HHJ45_19080 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HHJ45_19085 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HHJ45_19090 ENOG4105CXN decarboxylase HHJ45_19100 ENOG4105C0B DNA polymerase III (alpha subunit) HHJ45_19125 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HHJ45_19130 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HHJ45_19140 ENOG4105DZP Membrane-associated zinc metalloprotease HHJ45_19145 ENOG4105KNE Phosphatidate cytidylyltransferase HHJ45_19150 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HHJ45_19155 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HHJ45_19180 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HHJ45_19200 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HHJ45_19205 ENOG4105C0H protease HHJ45_19220 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HHJ45_19225 ENOG4105EN6 Membrane HHJ45_19250 ENOG4105S6R Iron-hydroxamate transporter permease subunit HHJ45_19255 ENOG4105J76 Periplasmic binding protein HHJ45_19260 ENOG4105E0A ABC, transporter HHJ45_19265 ENOG4105E0K tonB-dependent siderophore receptor HHJ45_19270 ENOG4105BZ4 penicillin-binding protein HHJ45_19275 ENOG4105CQ7 ATP-dependent helicase HHJ45_19280 ENOG4107XID 2'-5' rna ligase HHJ45_19300 ENOG4105DJ0 Poly(A) Polymerase HHJ45_19305 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HHJ45_19315 ENOG4108VEV chaperone HHJ45_19320 ENOG4105CW0 outer membrane usher protein HHJ45_19325 ENOG4108XEY fimbrial-like adhesin protein HHJ45_19330 ENOG4105SYG Fimbrial protein HHJ45_19335 ENOG4105SN2 fimbrial-like adhesin protein HHJ45_19340 ENOG4105P0Q fimbrial-like protein YadC HHJ45_19355 ENOG4108A32 Transposase HHJ45_19365 ENOG4107BJW polysaccharide deacetylase HHJ45_19370 ENOG4108YTN IIa component HHJ45_19375 ENOG4105E3A (ABC) transporter HHJ45_19380 ENOG4105DA5 (ABC) transporter HHJ45_19385 ENOG41077A9 carbonic anhydrase HHJ45_19390 ENOG4108UGV hypoxanthine phosphoribosyltransferase HHJ45_19395 ENOG4105DZG Dehydrogenase HHJ45_19405 ENOG4105E3B Multicopper oxidase HHJ45_19410 ENOG4108ZRK uncharacterized protein yacC HHJ45_19430 ENOG4107QIJ Aconitate hydratase 2 HHJ45_19435 ENOG4108NST exported protein HHJ45_19440 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ45_19445 ENOG4107QSN dihydrolipoamide acetyltransferase HHJ45_19450 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HHJ45_19455 ENOG41073TP transcriptional regulator HHJ45_19460 ENOG4105C85 amino acid HHJ45_19465 ENOG4106A72 regulatory protein AmpE HHJ45_19470 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ45_19475 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ45_19480 ENOG4108ZUW Major pilin subunit HHJ45_19485 ENOG4107QHF type ii secretion system protein e HHJ45_19490 ENOG4105D7Q type ii secretion system HHJ45_19500 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ45_19515 ENOG4105M6F mutator MutT protein HHJ45_19525 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) HHJ45_19535 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HHJ45_19540 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HHJ45_19545 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HHJ45_19550 ENOG4105CPF Cell wall formation (By similarity) HHJ45_19565 ENOG4105CNI cell division protein FtsW HHJ45_19580 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HHJ45_19585 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HHJ45_19590 ENOG4105CJN penicillin-binding protein HHJ45_19595 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HHJ45_19610 ENOG4107B7Y DNA-binding transcriptional regulator FruR HHJ45_19620 ENOG4108ZP8 Acetolactate synthase small subunit HHJ45_19625 ENOG4105C7K acetolactate synthase HHJ45_19630 ENOG41064T2 transcriptional regulator, lysR family HHJ45_19645 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HHJ45_19660 ENOG4105S8Q sugar efflux transporter HHJ45_19675 ENOG4105DP9 ABC transporter HHJ45_19680 ENOG4106SMU thiamine transporter membrane protein HHJ45_19690 ENOG4108KF1 Membrane HHJ45_19695 ENOG41063TF transcriptional regulator (AraC HHJ45_19710 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ45_19715 ENOG4105CQ2 DNA polymerase HHJ45_19720 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ45_19725 ENOG4105D3G Pseudouridine synthase HHJ45_19735 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HHJ45_19740 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HHJ45_19745 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HHJ45_19770 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HHJ45_19785 ENOG4105C54 Major Facilitator superfamily HHJ45_19790 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HHJ45_19795 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ45_19800 ENOG4105C10 Electron transfer flavoprotein HHJ45_19840 ENOG4106YT9 Enoyl-CoA hydratase HHJ45_19850 ENOG4108XNW Transcriptional activatory protein CaiF HHJ45_19855 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HHJ45_19860 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HHJ45_19880 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HHJ45_19890 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HHJ45_19895 ENOG4105DTN riboflavin biosynthesis protein ribF HHJ45_19900 ENOG410647N response to DNA damage stimulus HHJ45_19925 ENOG41063Z6 transcriptional regulator, lysR family HHJ45_19935 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ45_19955 ENOG4108QUJ UPF0174 protein YaaW HHJ45_19960 ENOG4106HK8 GPR1 FUN34 yaaH family protein HHJ45_19965 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ45_19970 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ45_19975 ENOG4105BZG amino acid carrier protein HHJ45_19990 ENOG41062C6 Protein of unknown function (DUF2502) HHJ45_19995 ENOG4105D98 threonine synthase HHJ45_20005 ENOG4105CFH Aspartokinase HHJ45_20015 ENOG4106FVC RNA methyltransferase HHJ45_20020 ENOG410759A HHJ45_20025 ENOG41065U4 response regulator HHJ45_20030 ENOG4105CT7 inner membrane cred family protein HHJ45_20035 ENOG4105EB3 Histidine kinase HHJ45_20040 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ45_20045 ENOG4108RH0 Crea protein HHJ45_20050 ENOG4105UEI Transcriptional Regulator AraC Family HHJ45_20060 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ45_20070 ENOG4107SC1 transglycosylase HHJ45_20075 ENOG4105C5H ABC transporter HHJ45_20080 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ45_20085 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HHJ45_20090 ENOG4105EAC phosphoserine phosphatase HHJ45_20095 ENOG41062Z9 Membrane HHJ45_20130 ENOG4105G0K glycine radical enzyme YjjI family HHJ45_20135 ENOG41076CZ activating enzyme HHJ45_20140 ENOG4105EYA deoxyribonuclease HHJ45_20145 ENOG4108NRW Phospholipase, patatin family HHJ45_20155 ENOG4105K3G Periplasmic Protein HHJ45_20165 ENOG4105PAD Hydrolase HHJ45_20170 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HHJ45_20175 ENOG4108WPU DNA polymerase III subunit psi HHJ45_20200 ENOG4105YBH Protein of unknown function (DUF1435) HHJ45_20205 ENOG4108819 ferric iron reductase HHJ45_20210 ENOG4108T94 DNA-binding transcriptional activator BglJ HHJ45_20215 ENOG4108N8T regulatoR HHJ45_20220 ENOG4105DWK Membrane HHJ45_20235 ENOG4106CVF DNA replication protein HHJ45_20240 ENOG4105RI1 glycoprotein receptor HHJ45_20250 ENOG4105CPQ Dehydrogenase HHJ45_20255 ENOG410617M Transcriptional regulator HHJ45_20260 ENOG4108I5G Major Facilitator superfamily HHJ45_20265 ENOG4105C8Q Methyl-accepting chemotaxis HHJ45_20270 ENOG4108V8F Transcriptional regulator, MarR family HHJ45_20275 ENOG4105ERH Fumarylacetoacetate hydrolase HHJ45_20280 ENOG4105C26 Dehydrogenase HHJ45_20285 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HHJ45_20300 ENOG4105CNV Aldolase HHJ45_20315 ENOG4105EFA 4-hydroxyphenylacetate HHJ45_20320 ENOG4107UWN reductase HHJ45_20325 ENOG4105D22 carbon starvation protein HHJ45_20330 ENOG4105VCD cytoplasmic protein HHJ45_20335 ENOG4105CKI cobalamin synthesis protein HHJ45_20345 ENOG4106DIZ Domain of unknown function (DUF1127) HHJ45_20350 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ45_20360 ENOG41083G8 Multidrug resistance protein MdtM HHJ45_20365 ENOG4106BRA Membrane HHJ45_20370 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HHJ45_20375 ENOG4105CIZ coA-substrate-specific enzyme activase HHJ45_20390 ENOG4105CBP Major Facilitator HHJ45_20400 ENOG41074DU domain protein HHJ45_20405 ENOG4108P2H Inner membrane protein YjiG HHJ45_20410 ENOG4105DYB Isoaspartyl dipeptidase HHJ45_20415 ENOG4107YNJ LysR family Transcriptional regulator HHJ45_20435 ENOG4105C6F GntR Family Transcriptional Regulator HHJ45_20440 ENOG4105DEI Mannitol dehydrogenase HHJ45_20450 ENOG4107EFN gluconate transport system permease 3 HHJ45_20455 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HHJ45_20460 ENOG4108T65 Fimbrial HHJ45_20465 ENOG4108SQA Fimbrial HHJ45_20470 ENOG4105CW0 outer membrane usher protein HHJ45_20475 ENOG4108NAE Fimbrial chaperone protein HHJ45_20480 ENOG4108S54 Fimbrial protein HHJ45_20490 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HHJ45_20495 ENOG4108W9T type 1 fimbriae regulatory protein HHJ45_20500 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HHJ45_20605 ENOG4105DQ4 alcohol dehydrogenase HHJ45_20610 ENOG4105D7A ATP-binding protein HHJ45_20615 ENOG4108K5H permease YjgP YjgQ family protein HHJ45_20620 ENOG4108M8S permease YjgP YjgQ family protein HHJ45_20630 ENOG4105MYG DNA polymerase iii, chi subunit HHJ45_20635 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HHJ45_20645 ENOG4108MJ3 acetyltransferase HHJ45_20650 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HHJ45_20670 ENOG4105XEP YhcH YjgK YiaL family protein HHJ45_20675 ENOG4108XFH Transcriptional regulator HHJ45_20680 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HHJ45_20685 ENOG4108UQ8 endoribonuclease L-psp HHJ45_20690 ENOG4107C93 pyrBI operon leader peptide HHJ45_20705 ENOG4105KME endoribonuclease L-psp HHJ45_20715 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HHJ45_20725 ENOG4105D4X repressor HHJ45_20730 ENOG4105C5Y PTS System HHJ45_20735 ENOG4105CG3 alpha amylase, catalytic region HHJ45_20740 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HHJ45_20745 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HHJ45_20755 ENOG4105CMS peptidase U62, modulator of DNA gyrase HHJ45_20765 ENOG4105DFU Cell wall formation (By similarity) HHJ45_20775 ENOG41062B0 ABC transporter, permease HHJ45_20780 ENOG4107R9N ABC transporter HHJ45_20785 ENOG4105C2J ABC transporter HHJ45_20790 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HHJ45_20795 ENOG4105F0N pyrophosphate phospho-hydrolase HHJ45_20800 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ45_20805 ENOG41087RY SpoVT_AbrB HHJ45_20810 ENOG4108ZHD aig2 family HHJ45_20815 ENOG4105MA0 exported protein HHJ45_20820 ENOG4105CFU surface antigen HHJ45_20830 ENOG4105C37 (CBS) domain HHJ45_20835 ENOG41061GZ Protein of unknown function (DUF1107) HHJ45_20840 ENOG4108UUE Transcriptional regulator HHJ45_20845 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HHJ45_20850 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HHJ45_20855 ENOG4105KVH Transcriptional regulator HHJ45_20860 ENOG4105ECR NmrA family HHJ45_20865 ENOG4105DXC membrane HHJ45_20875 ENOG4105C85 amino acid HHJ45_20880 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ45_20885 ENOG4105FHY Opacity-associated protein A HHJ45_20895 ENOG4105CHR reductase HHJ45_20905 ENOG4105E39 Enoyl-CoA hydratase HHJ45_20910 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ45_20915 ENOG4107S3R L-aspartate oxidase HHJ45_20920 ENOG41069H7 transport system small permease component HHJ45_20925 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ45_20930 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ45_20940 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HHJ45_20955 ENOG4105KIT UPF0379 protein yjfY HHJ45_20975 ENOG4106ETB IIa component HHJ45_20980 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HHJ45_20985 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ45_21000 ENOG4108MXZ Esterase HHJ45_21005 ENOG4105WSB biofilm stress and motility protein A HHJ45_21010 ENOG4105S17 UPF0379 protein yjfN HHJ45_21015 ENOG4105CSU acyl-Coa dehydrogenase HHJ45_21020 ENOG4106032 Glutathionylspermidine synthase HHJ45_21025 ENOG4108KXT Conserved Protein HHJ45_21030 ENOG4105Z6B inner membrane protein yjfl HHJ45_21035 ENOG4107VNS Protein of unknown function (DUF2491) HHJ45_21040 ENOG4108P9J Phage shock protein A HHJ45_21045 ENOG4105FUX Conserved Protein HHJ45_21050 ENOG4105C2N RNA methyltransferase TrmH family group 3 HHJ45_21055 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HHJ45_21075 ENOG4105EPW hflc protein HHJ45_21080 ENOG4107QJR hflk protein HHJ45_21085 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HHJ45_21105 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ45_21110 ENOG4105K8N protein family UPF0079, ATPase HHJ45_21115 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HHJ45_21120 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HHJ45_21160 ENOG4105EGS Mechanosensitive ion channel HHJ45_21165 ENOG4107SC7 Inner membrane transporter yjeM HHJ45_21175 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ45_21180 ENOG4105E33 succinate dehydrogenase HHJ45_21195 ENOG41066YJ Beta-lactamase HHJ45_21200 ENOG4105QNF Outer membrane lipoprotein HHJ45_21205 ENOG4105KPY Small multidrug resistance protein HHJ45_21210 ENOG4106BSU Entericidin B HHJ45_21215 ENOG4107PEH Entericidin EcnA/B family HHJ45_21225 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HHJ45_21230 ENOG4105MTB Uncharacterized protein YjeJ HHJ45_21235 ENOG4108ZVF (LipO)protein HHJ45_21250 ENOG4105DVH amino acid HHJ45_21255 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HHJ45_21260 ENOG4108IJ0 Aspartate ammonia-lyase HHJ45_21265 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ45_21280 ENOG4108SIC Transcriptional regulator HHJ45_21335 ENOG41067TZ transcriptional regulator, MarR family HHJ45_21365 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR HHJ45_21375 ENOG4106P2F Pfam:Pili_assembly_C HHJ45_21380 ENOG4106PG1 outer membrane usher protein HHJ45_21385 ENOG4108ZJG MrfB protein HHJ45_21420 ENOG4105EKQ RNA-directed DNA polymerase HHJ45_21520 ENOG4108YXQ IS66 Orf2 family protein HHJ45_21525 ENOG4105E5H Transposase HHJ45_21560 ENOG4105TS0 gtp-binding protein HHJ45_21565 ENOG4108KZE transcriptional regulator HHJ45_21580 ENOG4106H6R UPF0380 protein HHJ45_21585 ENOG4105MFG Antirestriction protein HHJ45_21590 ENOG4108YGG dna repair protein HHJ45_21600 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ45_21605 ENOG4105EKQ RNA-directed DNA polymerase HHJ45_21635 ENOG4108M3R transcriptional activator CadC HHJ45_21640 ENOG4105D5Q Arginine ornithine antiporter HHJ45_21645 ENOG4105CXN decarboxylase HHJ45_21650 ENOG4105DUX Transporter HHJ45_21655 ENOG4105CRK lysyL-tRNA synthetase HHJ45_21670 ENOG410830R acetyltransferase HHJ45_21675 ENOG4105VR1 Pfam:DUF1271 HHJ45_21680 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ45_21685 ENOG4108MRH transcriptional regulatory protein HHJ45_21690 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ45_21695 ENOG4107GFK fumarate HHJ45_21700 ENOG4108R5S membrane HHJ45_21705 ENOG4105CT4 transporter HHJ45_21710 ENOG4105F8D glycoside hydrolase family 4 HHJ45_21715 ENOG4108K2B transcriptional regulator HHJ45_21720 ENOG4105CXN decarboxylase HHJ45_21725 ENOG4106ZGR Transcriptional regulator HHJ45_21730 ENOG4105D5Q Arginine ornithine antiporter HHJ45_21735 ENOG4105DIJ Phosphoethanolamine transferase HHJ45_21740 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ45_21745 ENOG4105ECM Sensor protein basS pmrB HHJ45_21755 ENOG4105CSH Transporter HHJ45_21760 ENOG4108YIV HHJ45_21765 ENOG4108F5E vimentin HHJ45_21770 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HHJ45_21775 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HHJ45_21780 ENOG4105D5T phosphonate abc transporter HHJ45_21785 ENOG4105EHI Phosphonate ABC transporter, periplasmic HHJ45_21795 ENOG4107RJJ Transcriptional regulator HHJ45_21800 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HHJ45_21805 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HHJ45_21810 ENOG4105EKV Phosphonate metabolism protein HHJ45_21815 ENOG4105FT8 Phosphonate metabolism HHJ45_21820 ENOG4105ENV phosphonate C-P lyase system protein PhnK HHJ45_21825 ENOG4105HRV phosphonate c-p lyase system protein phnl HHJ45_21830 ENOG4105FD8 phosphonate metabolism protein PhnM HHJ45_21835 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) HHJ45_21840 ENOG410849A acetyltransferase, (GNAT) family HHJ45_21845 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HHJ45_21855 ENOG4108YZG isomerase HHJ45_21860 ENOG4105EUZ Beta-lactamase domain protein HHJ45_21865 ENOG4106833 HHJ45_21870 ENOG4105J12 Multidrug resistance protein mdtN HHJ45_21875 ENOG4108MI0 Resistance protein HHJ45_21880 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ45_21890 ENOG41082ND Uncharacterized protein yjcO HHJ45_21895 ENOG4105CK2 sodium dicarboxylate symporter HHJ45_21900 ENOG4108W0S formate-dependent nitrite reductase complex HHJ45_21910 ENOG4108QKW cytochrome c-type biogenesis protein HHJ45_21915 ENOG4105DVI reductase, NrfD HHJ45_21920 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ45_21925 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HHJ45_21935 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ45_21940 ENOG41062QD Membrane HHJ45_21955 ENOG4105EEQ Na H antiporter HHJ45_21960 ENOG4105C7N Xanthine uracil vitamin C permease HHJ45_21965 ENOG4108Z4X TRANSCRIPTIONal HHJ45_21970 ENOG4108W3Q Transcriptional regulator HHJ45_21975 ENOG4108M8H domain protein HHJ45_21980 ENOG4105PMV Membrane HHJ45_21985 ENOG4108UUM single-stranded DNA-binding protein HHJ45_21990 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HHJ45_21995 ENOG4105MSB protein, conserved in bacteria HHJ45_22000 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HHJ45_22005 ENOG4105F0S class B acid phosphatase HHJ45_22020 ENOG4105CGF Aromatic amino acid aminotransferase HHJ45_22025 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ45_22030 ENOG4105CDU Replicative dna helicase HHJ45_22035 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HHJ45_22040 ENOG4105P4Z Phage shock protein G HHJ45_22045 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ45_22055 ENOG4105MYN Zinc uptake regulation protein HHJ45_22060 ENOG4105VDW Csbd family HHJ45_22065 ENOG4107R73 Mate efflux family protein HHJ45_22075 ENOG41080IJ Diacylglycerol kinase HHJ45_22100 ENOG4107W52 maltose operon periplasmic protein HHJ45_22110 ENOG4108IJ9 (ABC) transporter HHJ45_22115 ENOG4107FKK extracellular solute-binding protein family 1 HHJ45_22120 ENOG4105D56 permease protein HHJ45_22125 ENOG4105EG2 ABC transporter, permease HHJ45_22130 ENOG4107QNK )-transporter HHJ45_22145 ENOG4105E3R (LipO)protein HHJ45_22150 ENOG4108Q9C Periplasmic Protein HHJ45_22155 ENOG4108MDC (LipO)protein HHJ45_22170 ENOG4105CFH Aspartokinase HHJ45_22175 ENOG4108WZA zeta toxin HHJ45_22180 ENOG410756H nucleotidyltransferase HHJ45_22190 ENOG4108ZR5 Conserved Protein HHJ45_22195 ENOG4105FE9 pseudouridine synthase HHJ45_22205 ENOG4105EAM Na Pi-cotransporter HHJ45_22210 ENOG4105C3R Methionine synthase HHJ45_22215 ENOG41069M3 Transcriptional regulator HHJ45_22230 ENOG4108I9X Isocitrate lyase HHJ45_22235 ENOG4107QP3 malate synthase g HHJ45_22245 ENOG4105K5X acetyltransferase HHJ45_22275 ENOG4105C12 Phosphoribosylglycinamide synthetase HHJ45_22280 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ45_22285 ENOG4105BZU Histidine kinase HHJ45_22290 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HHJ45_22295 ENOG4108T8B Protein of unknown function (DUF1481) HHJ45_22305 ENOG4105R2J Conserved Protein HHJ45_22330 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) HHJ45_22340 ENOG4105D06 uba thif-type nad fad binding protein HHJ45_22345 ENOG4105WHD thiamine biosynthesis protein ThiS HHJ45_22355 ENOG4105D41 biosynthesis protein thiH HHJ45_22360 ENOG410645W Thiamin biosynthesis protein ThiH HHJ45_22395 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HHJ45_22400 ENOG4105PM1 preprotein translocase subunit SecE HHJ45_22435 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HHJ45_22480 ENOG4108Y73 Membrane HHJ45_22485 ENOG4105EJ2 Transcriptional regulator HHJ45_22495 ENOG4105C5Q Transcriptional regulator HHJ45_22500 ENOG4108I5G Major Facilitator superfamily HHJ45_22505 ENOG4105CXK mandelate racemase muconate lactonizing HHJ45_22520 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HHJ45_22525 ENOG4105CWC Acetylornithine deacetylase HHJ45_22535 ENOG4105DIJ Phosphoethanolamine transferase HHJ45_22540 ENOG4106R3P AraC family transcriptional regulator HHJ45_22545 ENOG4108XCZ PTS System HHJ45_22550 ENOG4108AHH pyruvate formate lyase II activase HHJ45_22560 ENOG4108YRF PTS System HHJ45_22565 ENOG4105DM4 PTS System HHJ45_22570 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ45_22575 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ45_22580 ENOG4105DCT glycerol dehydrogenase HHJ45_22585 ENOG4108XC3 NADH ubiquinone oxidoreductase HHJ45_22590 ENOG4108Q5Y Membrane HHJ45_22600 ENOG4105SYT Methylenetetrahydrofolate reductase HHJ45_22605 ENOG4105CFH Aspartokinase HHJ45_22610 ENOG4105C28 cystathionine HHJ45_22620 ENOG4107S01 Repressor protein MetJ HHJ45_22665 ENOG4105C25 Primosomal protein n' HHJ45_22670 ENOG4105ETE Transcriptional regulator (LacI family HHJ45_22675 ENOG41063M6 Cell Division Protein HHJ45_22690 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HHJ45_22705 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ45_22715 ENOG4105CBT Fructose-1,6-bisphosphatase HHJ45_22720 ENOG4105DP0 ferredoxin-NADP reductase HHJ45_22730 ENOG41065TG regulatoR HHJ45_22735 ENOG4108VTS Membrane HHJ45_22740 ENOG4105EBK exported protein HHJ45_22755 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HHJ45_22770 ENOG4105FMW periplasmic HHJ45_22775 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ45_22780 ENOG4105E0F Histidine kinase HHJ45_22785 ENOG4108RPX mosc domain containing protein HHJ45_22805 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ45_22835 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) HHJ45_22845 ENOG41064BA PTS system, fructose-specific, IIA component HHJ45_22850 ENOG4105DM4 PTS System HHJ45_22855 ENOG4105CN9 Peptidase m42 family protein HHJ45_22860 ENOG4106C3V frv operon regulatory protein HHJ45_22865 ENOG4108V87 frv operon regulatory protein HHJ45_22880 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ45_22885 ENOG4108MG3 formate dehydrogenase HHJ45_22895 ENOG41068KX affects formate dehydrogenase-N HHJ45_22910 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HHJ45_22920 ENOG4105SUU thioesterase domain HHJ45_22935 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HHJ45_22940 ENOG4105E98 transcriptional regulator DeoR family HHJ45_22945 ENOG4108MGF sugar kinase HHJ45_22950 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ45_22955 ENOG4105D2M Aldolase HHJ45_22960 ENOG4107QKS N-acylglucosamine 2-epimerase HHJ45_22965 ENOG4107WI4 Aldose-1-epimerase HHJ45_22970 ENOG4105CJQ hydrolase, family 31 HHJ45_22975 ENOG4105CT4 transporter HHJ45_22980 ENOG4105CT4 transporter HHJ45_22985 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HHJ45_22990 ENOG4105R9B Major Facilitator HHJ45_22995 ENOG4108KHF Resistance protein HHJ45_23000 ENOG4108K85 Transcriptional regulator HHJ45_23005 ENOG4105CI3 gtp-binding protein typa HHJ45_23010 ENOG4105C5F glutamine synthetase HHJ45_23015 ENOG4105CUX Signal transduction histidine kinase HHJ45_23020 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ45_23025 ENOG4106FIY HHJ45_23030 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ45_23045 ENOG4105C2M dna polymerase I HHJ45_23050 ENOG4106HNH Acyl-transferase HHJ45_23075 ENOG4105E27 serine threonine protein kinase HHJ45_23080 ENOG4105PC1 Conserved Protein HHJ45_23085 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HHJ45_23090 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HHJ45_23120 ENOG4108RR8 protoporphyrinogen oxidase HHJ45_23125 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HHJ45_23130 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HHJ45_23140 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ45_23150 ENOG4108EX3 reductase HHJ45_23155 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ45_23160 ENOG4105MDZ Transcriptional activator rfaH HHJ45_23170 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HHJ45_23175 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HHJ45_23180 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HHJ45_23190 ENOG4105JC1 sterol-binding domain protein HHJ45_23200 ENOG4105CGY Dna recombination protein HHJ45_23205 ENOG4108I5U Uridine phosphorylase HHJ45_23210 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HHJ45_23220 ENOG4105DZ2 Transcriptional regulator HHJ45_23225 ENOG4105EMK carboxylate amino acid amine transporter HHJ45_23230 ENOG4105DQF Hydrolase HHJ45_23235 ENOG4108EUD Lysophospholipase HHJ45_23240 ENOG410829K Lysine exporter protein (Lyse ygga) HHJ45_23245 ENOG4105CCF Lysine exporter protein (Lyse ygga) HHJ45_23250 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ45_23255 ENOG4105HDD phospholipase HHJ45_23260 ENOG4108VUY thioesterase Superfamily protein HHJ45_23265 ENOG4105FR1 rard protein HHJ45_23275 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ45_23290 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ45_23295 ENOG4108T58 Mg2 transport protein CorA HHJ45_23300 ENOG4105C4R Atp-dependent dna helicase HHJ45_23305 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HHJ45_23315 ENOG4105CT0 Protein of unknown function, DUF484 HHJ45_23325 ENOG4105S7Z (LipO)protein HHJ45_23350 ENOG4107T0K Adenylate cyclase HHJ45_23360 ENOG41076E6 Uroporphyrinogen-III Synthase HHJ45_23365 ENOG4105ECF c-methyltransferase HHJ45_23370 ENOG410601J HemY protein HHJ45_23375 ENOG4105ENH Sulfatase HHJ45_23380 ENOG4105C4X radical SAM domain protein HHJ45_23405 ENOG4105C85 amino acid HHJ45_23415 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) HHJ45_23425 ENOG4105EGZ biosynthesis protein HHJ45_23430 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HHJ45_23435 ENOG4108WJ1 acetyltransferase HHJ45_23440 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ45_23445 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ45_23450 ENOG4107QQG Dehydrogenase HHJ45_23455 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ45_23460 ENOG4105SFE lipopolysaccharide biosynthesis protein HHJ45_23465 ENOG4105ESV Glycosyl transferase, family 4 HHJ45_23470 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HHJ45_23495 ENOG4105C4R Atp-dependent dna helicase HHJ45_23505 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HHJ45_23515 ENOG4105EMY transcriptional regulator HHJ45_23525 ENOG4105C7B Threonine dehydratase HHJ45_23535 ENOG4105CM2 brancheD-chain amino acid aminotransferase HHJ45_23540 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HHJ45_23560 ENOG4105C0P Mg chelatase subunit ChlI HHJ45_23565 ENOG4108WFC UPF0438 protein yifE HHJ45_23605 ENOG4107EJG GntR family transcriptional regulator HHJ45_23610 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ45_23615 ENOG4105ETE Transcriptional regulator (LacI family HHJ45_23620 ENOG4108RVA ribokinase HHJ45_23625 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ45_23630 ENOG4105CNN ABC, transporter HHJ45_23635 ENOG4105C2J ABC transporter HHJ45_23665 ENOG4108VVK transcriptional Regulator, AsnC HHJ45_23670 ENOG4105QTB Flavodoxin HHJ45_23685 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HHJ45_23735 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HHJ45_23740 ENOG4108RQP Major type 1 subunit fimbrin HHJ45_23750 ENOG4105CW0 outer membrane usher protein HHJ45_23760 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HHJ45_23765 ENOG4105C8U phosphate abc transporter HHJ45_23770 ENOG4105E2Z phosphate ABC transporter (Permease HHJ45_23775 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HHJ45_23780 ENOG4108UTW Plays a role in the regulation of phosphate uptake HHJ45_23785 ENOG4105CID antiterminator HHJ45_23790 ENOG4105C5Y PTS System HHJ45_23795 ENOG4105CS2 ec 3.2.1.21 HHJ45_23805 ENOG4105DYC esterase HHJ45_23810 ENOG4107VKM 6-phosphogluconolactonase HHJ45_23815 ENOG4106611 bacteriocin immunity HHJ45_23825 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HHJ45_23830 ENOG4105C7N Xanthine uracil vitamin C permease HHJ45_23835 ENOG4108YYH Nadph-dependent fmn reductase HHJ45_23840 ENOG4105E8Q phosphopantetheinyl transferase HHJ45_23850 ENOG4105CNH Multidrug resistance protein MdtL HHJ45_23855 ENOG4108P6C Tryptophan transporter of low affinity HHJ45_23890 ENOG4105VG0 50S ribosomal protein l34 HHJ45_23940 ENOG4105EKQ RNA-directed DNA polymerase HHJ45_23970 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ45_23980 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ45_24015 ENOG4105QYK bacteriophage lambda Bor protein homolog HHJ45_24040 ENOG4105E93 esterase HHJ45_24045 ENOG4105NIV Esterase HHJ45_24050 ENOG4107RNH Outer membrane receptor FepA HHJ45_24075 ENOG4108MBX Secretion Protein HHJ45_24105 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ45_24185 ENOG4108BUD transposase HHJ45_24205 ENOG4108BUD transposase HHJ45_24230 ENOG4108R0M Aminoglycoside HHJ45_24240 ENOG4108BUD transposase HHJ45_24250 ENOG4105BZU Histidine kinase HHJ45_24280 ENOG4108VSE mercuric transport protein HHJ45_24285 ENOG4105W1Y Transcriptional regulator HHJ45_24290 ENOG4106CQM replication HHJ45_24315 ENOG4105KK6 nuclease HHJ45_24325 ENOG4107CBI conjugal transfer fertility inhibition protein HHJ45_24330 ENOG4107U2T alpha beta HHJ45_24530 ENOG4105FEQ ParB domain protein nuclease HHJ45_24630 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) HHJ45_24635 ENOG4105DUU IucA IucC family protein HHJ45_24655 ENOG41082CG Protein CrcB homolog HHJ45_24670 ENOG4105CC5 ABC transporter HHJ45_24675 ENOG4105CC5 ABC transporter HHJ45_24680 ENOG4105DIK (ABC) transporter HHJ45_24710 ENOG4105D13 transposase HHJ45_24715 ENOG4108BUD transposase HHJ45_24955 ENOG4105KF5 hemolysin expression-modulating protein HHJ45_24990 ENOG4107XMK single-stranded DNA-binding protein