locus-tag	class	description
HHJ45_00010	COG0592	DNA-directed DNA polymerase activity
HHJ45_00020	COG0187	DNA topoisomerase II activity
HHJ45_00030	COG3753	Protein conserved in bacteria
HHJ45_00035	COG0561	phosphatase activity
HHJ45_00045	COG2186	Transcriptional regulator
HHJ45_00050	COG3734	2-keto-3-deoxy-galactonokinase
HHJ45_00055	COG0800	Aldolase
HHJ45_00065	COG2271	Major facilitator Superfamily
HHJ45_00075	COG0823	Involved in the tonB-independent uptake of proteins
HHJ45_00080	COG5645	(Lipo)protein
HHJ45_00100	COG2188	Transcriptional regulator
HHJ45_00120	COG2207	Transcriptional regulator
HHJ45_00125	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHJ45_00130	COG3119	arylsulfatase activity
HHJ45_00140	COG2149	membrane
HHJ45_00150	COG0641	radical SAM
HHJ45_00155	COG2814	Major facilitator Superfamily
HHJ45_00170	COG0028	Belongs to the TPP enzyme family
HHJ45_00175	COG0440	acetolactate synthase activity
HHJ45_00180	COG2197	response regulator
HHJ45_00185	COG3851	Histidine kinase
HHJ45_00190	COG2271	Major facilitator Superfamily
HHJ45_00195	COG2271	Major facilitator Superfamily
HHJ45_00205	COG2252	PERMEase
HHJ45_00225	COG1464	Belongs to the NlpA lipoprotein family
HHJ45_00230	COG0697	spore germination
HHJ45_00235	COG2814	Major facilitator Superfamily
HHJ45_00250	COG2211	Major facilitator Superfamily
HHJ45_00255	COG1501	Belongs to the glycosyl hydrolase 31 family
HHJ45_00260	COG2982	Protein involved in outer membrane biogenesis
HHJ45_00265	COG2233	PERMEase
HHJ45_00270	COG0786	glutamate:sodium symporter activity
HHJ45_00280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHJ45_00285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ45_00290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHJ45_00300	COG0194	GDP metabolic process
HHJ45_00310	COG2860	membrane
HHJ45_00315	COG3645	SOS response
HHJ45_00320	COG3645	SOS response
HHJ45_00410	COG1561	YicC-like family, N-terminal region
HHJ45_00435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHJ45_00465	COG1519	Transferase
HHJ45_00470	COG0859	PFAM glycosyl transferase family 9
HHJ45_00475	COG0438	transferase activity, transferring glycosyl groups
HHJ45_00480	COG0515	serine threonine protein kinase
HHJ45_00510	COG3307	-O-antigen
HHJ45_00515	COG0859	PFAM glycosyl transferase family 9
HHJ45_00520	COG0859	PFAM glycosyl transferase family 9
HHJ45_00530	COG0156	8-amino-7-oxononanoate synthase activity
HHJ45_00540	COG1216	Glycosyl transferase, family 2
HHJ45_00545	COG2861	carbohydrate metabolic process
HHJ45_00550	COG4942	peptidase
HHJ45_00560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ45_00565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ45_00580	COG1045	serine acetyltransferase
HHJ45_00585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HHJ45_00595	COG2186	Transcriptional regulator
HHJ45_00600	COG1620	l-lactate permease
HHJ45_00605	COG5295	Hep Hag repeat protein
HHJ45_00625	COG3722	fumarate hydratase activity
HHJ45_00635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_00635	COG2213	PTS system mannitol-specific
HHJ45_00645	COG1566	PFAM secretion protein HlyD family protein
HHJ45_00655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HHJ45_00660	COG3209	COG3209 Rhs family protein
HHJ45_00675	COG3209	COG3209 Rhs family protein
HHJ45_00680	COG0625	glutathione transferase activity
HHJ45_00690	COG3276	selenocysteine insertion sequence binding
HHJ45_00695	COG1454	alcohol dehydrogenase
HHJ45_00700	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_00715	COG1566	PFAM secretion protein HlyD family protein
HHJ45_00720	COG0583	DNA-binding transcription factor activity
HHJ45_00725	COG3713	MltA-interacting MipA family protein
HHJ45_00735	COG2211	Major facilitator Superfamily
HHJ45_00745	COG0235	Class ii aldolase
HHJ45_00750	COG3623	hexulose-6-phosphate isomerase
HHJ45_00755	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HHJ45_00760	COG1070	Carbohydrate kinase
HHJ45_00765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HHJ45_00770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HHJ45_00775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HHJ45_00780	COG2731	YhcH YjgK YiaL family protein
HHJ45_00790	COG1414	Transcriptional regulator
HHJ45_00795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_00800	COG3977	Valine--pyruvate aminotransferase
HHJ45_00805	COG0366	Alpha amylase catalytic
HHJ45_00810	COG2992	FlgJ-related protein
HHJ45_00815	COG2207	Transcriptional regulator
HHJ45_00815	COG1609	Transcriptional regulator
HHJ45_00820	COG4214	carbohydrate transport
HHJ45_00825	COG1129	ABC transporter
HHJ45_00830	COG4213	ABC transporter substrate-binding protein
HHJ45_00840	COG1070	Carbohydrate kinase
HHJ45_00845	COG4682	membrane
HHJ45_00850	COG4682	membrane
HHJ45_00855	COG3274	enterobacterial common antigen metabolic process
HHJ45_00880	COG1278	Cold shock
HHJ45_00885	COG2944	sequence-specific DNA binding
HHJ45_00900	COG2885	chlorophyll binding
HHJ45_00905	COG0243	molybdopterin cofactor binding
HHJ45_00910	COG0456	acetyltransferase
HHJ45_00915	COG2818	Glycosylase
HHJ45_00920	COG5571	outer membrane autotransporter
HHJ45_00925	COG2223	nitrite transmembrane transporter activity
HHJ45_00930	COG2194	sulfuric ester hydrolase activity
HHJ45_00955	COG0747	negative chemotaxis
HHJ45_00960	COG0601	transmembrane transport
HHJ45_00965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ45_00970	COG0444	Belongs to the ABC transporter superfamily
HHJ45_00975	COG4608	Belongs to the ABC transporter superfamily
HHJ45_00980	COG0814	amino acid
HHJ45_01015	COG1215	transferase activity, transferring glycosyl groups
HHJ45_01020	COG1215	transferase activity, transferring glycosyl groups
HHJ45_01025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HHJ45_01030	COG0457	Tetratricopeptide repeat
HHJ45_01030	COG3118	belongs to the thioredoxin family
HHJ45_01035	COG2200	EAL domain
HHJ45_01035	COG2199	diguanylate cyclase activity
HHJ45_01045	COG0612	Peptidase, M16
HHJ45_01055	COG2200	EAL domain
HHJ45_01060	COG2982	Protein involved in outer membrane biogenesis
HHJ45_01065	COG0477	Major facilitator Superfamily
HHJ45_01070	COG1295	ribonuclease BN
HHJ45_01075	COG0583	DNA-binding transcription factor activity
HHJ45_01080	COG2197	response regulator
HHJ45_01090	COG1858	cytochrome C peroxidase
HHJ45_01105	COG2207	Transcriptional regulator
HHJ45_01110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ45_01115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_01125	COG2771	luxR family
HHJ45_01130	COG3247	response to pH
HHJ45_01145	COG1285	pathogenesis
HHJ45_01150	COG2197	response regulator
HHJ45_01155	COG3065	identical protein binding
HHJ45_01175	COG1393	Belongs to the ArsC family
HHJ45_01180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHJ45_01185	COG0640	Transcriptional regulator
HHJ45_01195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ45_01200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HHJ45_01205	COG0339	signal peptide processing
HHJ45_01215	COG3104	oligopeptide transport
HHJ45_01220	COG0589	response to stress
HHJ45_01230	COG0306	phosphate transporter
HHJ45_01235	COG2081	HI0933 family
HHJ45_01270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_01275	COG1129	ABC transporter
HHJ45_01275	COG0842	Transport permease protein
HHJ45_01280	COG0842	Transport permease protein
HHJ45_01305	COG0444	Belongs to the ABC transporter superfamily
HHJ45_01310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ45_01315	COG0601	transmembrane transport
HHJ45_01320	COG0747	negative chemotaxis
HHJ45_01325	COG2091	lysine biosynthetic process via aminoadipic acid
HHJ45_01330	COG0628	permease
HHJ45_01345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHJ45_01360	COG3714	YhhN family
HHJ45_01370	COG3776	membrane
HHJ45_01375	COG0742	ribosomal rna small subunit methyltransferase
HHJ45_01380	COG0552	protein localization to endoplasmic reticulum
HHJ45_01385	COG2884	Cell division ATP-binding protein ftsE
HHJ45_01390	COG2177	Part of the ABC transporter FtsEX involved in
HHJ45_01395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ45_01400	COG0683	leucine binding
HHJ45_01415	COG0456	acetyltransferase
HHJ45_01420	COG0683	leucine binding
HHJ45_01425	COG0559	Belongs to the binding-protein-dependent transport system permease family
HHJ45_01430	COG4177	L-phenylalanine transmembrane transporter activity
HHJ45_01435	COG0411	ABC transporter
HHJ45_01440	COG0410	ABC transporter
HHJ45_01445	COG1653	transport
HHJ45_01450	COG1175	transmembrane transport
HHJ45_01460	COG3842	ATPase activity
HHJ45_01465	COG0584	glycerophosphoryl diester phosphodiesterase
HHJ45_01475	COG0405	Gamma-glutamyltransferase
HHJ45_01495	COG1247	-acetyltransferase
HHJ45_01500	COG0673	inositol 2-dehydrogenase activity
HHJ45_01505	COG1741	Belongs to the pirin family
HHJ45_01510	COG1609	Transcriptional regulator
HHJ45_01515	COG3265	gluconokinase activity
HHJ45_01520	COG2610	gluconate transmembrane transporter activity
HHJ45_01525	COG2095	MarC family integral membrane protein
HHJ45_01530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHJ45_01555	COG0058	SHG alpha-glucan phosphorylase activity
HHJ45_01560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HHJ45_01580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHJ45_01595	COG1349	DNA-binding transcription factor activity
HHJ45_01600	COG4650	regulator
HHJ45_01605	COG1690	Belongs to the RtcB family
HHJ45_01620	COG0058	SHG alpha-glucan phosphorylase activity
HHJ45_01625	COG1640	4-alpha-glucanotransferase
HHJ45_01630	COG2610	gluconate transmembrane transporter activity
HHJ45_01650	COG5464	transposase or invertase
HHJ45_01660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HHJ45_01665	COG1918	ferrous iron import across plasma membrane
HHJ45_01670	COG2183	response to ionizing radiation
HHJ45_01675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ45_01680	COG0745	RESPONSE REGULATOR receiver
HHJ45_01685	COG2205	protein histidine kinase activity
HHJ45_01705	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HHJ45_01715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HHJ45_01720	COG1011	Hydrolase
HHJ45_01730	COG0494	nUDIX hydrolase
HHJ45_01735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HHJ45_01740	COG4972	Pilus assembly protein
HHJ45_01745	COG3166	PFAM Fimbrial assembly family protein
HHJ45_01760	COG4796	Type ii and iii secretion system protein
HHJ45_01775	COG3266	domain, Protein
HHJ45_01780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HHJ45_01785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HHJ45_01790	COG0546	phosphoglycolate phosphatase activity
HHJ45_01795	COG0180	Tryptophanyl-tRNA synthetase
HHJ45_01800	COG2188	Transcriptional regulator
HHJ45_01810	COG3457	Alanine racemase
HHJ45_01815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHJ45_01820	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HHJ45_01835	COG0626	cystathionine gamma-synthase activity
HHJ45_01840	COG2188	Transcriptional regulator
HHJ45_01850	COG1082	Xylose isomerase domain protein TIM barrel
HHJ45_01855	COG2222	sugar isomerase
HHJ45_01860	COG0531	amino acid
HHJ45_01875	COG2116	formate transmembrane transporter activity
HHJ45_01880	COG2146	nitrite reductase [NAD(P)H] activity
HHJ45_01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHJ45_01895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHJ45_01905	COG2184	nucleotidyltransferase activity
HHJ45_01910	COG0512	Glutamine amidotransferase of anthranilate synthase
HHJ45_01915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HHJ45_01920	COG1289	transmembrane transporter activity
HHJ45_01925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ45_01930	COG1765	OsmC-like protein
HHJ45_01935	COG3954	Phosphoribulokinase
HHJ45_01945	COG0429	hydrolase of the alpha beta-hydrolase fold
HHJ45_01950	COG0488	(ABC) transporter
HHJ45_01965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HHJ45_01970	COG1047	Peptidyl-prolyl cis-trans
HHJ45_01980	COG0545	Peptidyl-prolyl cis-trans isomerase
HHJ45_01985	COG2964	Protein conserved in bacteria
HHJ45_02055	COG0089	rRNA binding
HHJ45_02145	COG0201	protein transport
HHJ45_02185	COG0789	Transcriptional regulator
HHJ45_02190	COG3036	rescue of stalled ribosome
HHJ45_02200	COG0569	domain protein
HHJ45_02220	COG0758	DNA mediated transformation
HHJ45_02230	COG0551	DNA topoisomerase type I activity
HHJ45_02250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHJ45_02290	COG1126	abc transporter atp-binding protein
HHJ45_02295	COG0765	amino acid transport
HHJ45_02300	COG4597	amino acid ABC transporter
HHJ45_02305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ45_02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_02325	COG1309	transcriptional regulator
HHJ45_02335	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HHJ45_02345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ45_02355	COG4145	pantothenate transmembrane transporter activity
HHJ45_02360	COG3924	membrane
HHJ45_02365	COG0439	Biotin carboxylase
HHJ45_02370	COG0511	ligase activity, forming carbon-carbon bonds
HHJ45_02375	COG0604	alcohol dehydrogenase
HHJ45_02380	COG2199	diguanylate cyclase activity
HHJ45_02380	COG2200	EAL domain
HHJ45_02385	COG1077	Cell shape determining protein MreB Mrl
HHJ45_02390	COG1792	Involved in formation and maintenance of cell shape
HHJ45_02395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HHJ45_02405	COG1530	ribonuclease E activity
HHJ45_02410	COG3164	Protein of unknown function
HHJ45_02415	COG0312	modulator of DNA gyrase
HHJ45_02420	COG0583	DNA-binding transcription factor activity
HHJ45_02440	COG2732	(Barnase) inhibitor
HHJ45_02460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ45_02465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ45_02470	COG3105	Protein conserved in bacteria
HHJ45_02475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HHJ45_02490	COG0625	glutathione transferase activity
HHJ45_02495	COG2969	positive regulation of protein catabolic process
HHJ45_02500	COG3069	C4-dicarboxylate transmembrane transporter activity
HHJ45_02530	COG2731	YhcH YjgK YiaL family protein
HHJ45_02535	COG4804	nuclease activity
HHJ45_02540	COG0493	'glutamate synthase
HHJ45_02545	COG0067	glutamate synthase
HHJ45_02545	COG0069	glutamate synthase activity
HHJ45_02545	COG0070	glutamate synthase
HHJ45_02550	COG1242	4 iron, 4 sulfur cluster binding
HHJ45_02555	COG0784	Response regulator, receiver
HHJ45_02555	COG2198	Histidine kinase
HHJ45_02555	COG5002	protein histidine kinase activity
HHJ45_02560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HHJ45_02570	COG0515	serine threonine protein kinase
HHJ45_02575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_02590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHJ45_02595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HHJ45_02600	COG1137	ATPase activity
HHJ45_02605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HHJ45_02610	COG3117	lipopolysaccharide transmembrane transporter activity
HHJ45_02615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HHJ45_02620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HHJ45_02620	COG0517	IMP dehydrogenase activity
HHJ45_02625	COG0530	calcium, potassium:sodium antiporter activity
HHJ45_02630	COG1127	ABC transporter
HHJ45_02635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HHJ45_02640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HHJ45_02645	COG2854	intermembrane phospholipid transfer
HHJ45_02650	COG3113	response to antibiotic
HHJ45_02655	COG5007	Belongs to the BolA IbaG family
HHJ45_02665	COG3423	Transcriptional regulator
HHJ45_02670	COG0142	geranyltranstransferase activity
HHJ45_02685	COG0697	spore germination
HHJ45_02695	COG2027	D-alanyl-D-alanine carboxypeptidase
HHJ45_02700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ45_02705	COG1534	Rna-binding protein
HHJ45_02715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHJ45_02720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHJ45_02730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HHJ45_02740	COG2194	sulfuric ester hydrolase activity
HHJ45_02760	COG0195	Participates in both transcription termination and antitermination
HHJ45_02800	COG0513	Belongs to the DEAD box helicase family
HHJ45_02805	COG0814	amino acid
HHJ45_02815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHJ45_02820	COG0826	peptidase U32
HHJ45_02825	COG0826	peptidase U32
HHJ45_02830	COG3154	lipid carrier protein
HHJ45_02835	COG3153	acetyltransferase
HHJ45_02850	COG0693	protein deglycase activity
HHJ45_02855	COG0702	epimerase
HHJ45_02860	COG0701	Predicted permease
HHJ45_02865	COG2823	Periplasmic or secreted lipoprotein
HHJ45_02885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHJ45_02890	COG3539	Fimbrial protein
HHJ45_02895	COG3188	usher protein
HHJ45_02900	COG3121	Chaperone
HHJ45_02905	COG3539	Fimbrial protein
HHJ45_02910	COG0363	glucosamine-6-phosphate deaminase activity
HHJ45_02915	COG3716	PTS system mannose fructose sorbose family IID component
HHJ45_02920	COG3715	PTS system
HHJ45_02925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_02935	COG2222	sugar isomerase
HHJ45_02940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ45_02945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_02950	COG3716	PTS system mannose fructose sorbose family IID component
HHJ45_02960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_02980	COG2002	toxin-antitoxin pair type II binding
HHJ45_02985	COG2721	sulfolactate sulfo-lyase activity
HHJ45_02990	COG2271	Major facilitator Superfamily
HHJ45_03000	COG2084	Dehydrogenase
HHJ45_03005	COG1929	Belongs to the glycerate kinase type-1 family
HHJ45_03035	COG0583	DNA-binding transcription factor activity
HHJ45_03040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ45_03050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHJ45_03055	COG1882	Formate acetyltransferase
HHJ45_03060	COG0251	oxidation-reduction process
HHJ45_03065	COG1760	l-serine dehydratase
HHJ45_03070	COG0814	amino acid
HHJ45_03085	COG1741	Belongs to the pirin family
HHJ45_03090	COG0583	DNA-binding transcription factor activity
HHJ45_03095	COG3152	Membrane
HHJ45_03100	COG3152	Membrane
HHJ45_03105	COG0435	Glutathione S-transferase
HHJ45_03110	COG2259	Doxx family
HHJ45_03120	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HHJ45_03125	COG4575	ribosome binding
HHJ45_03130	COG1422	Protein of unknown function (DUF1090)
HHJ45_03140	COG0586	Pfam SNARE associated Golgi protein
HHJ45_03145	COG2186	Transcriptional regulator
HHJ45_03170	COG2271	Major facilitator Superfamily
HHJ45_03180	COG2721	sulfolactate sulfo-lyase activity
HHJ45_03190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HHJ45_03200	COG0861	Integral membrane protein TerC family
HHJ45_03205	COG0673	inositol 2-dehydrogenase activity
HHJ45_03210	COG2949	membrane
HHJ45_03215	COG1451	nucleotide metabolic process
HHJ45_03230	COG5499	transcription regulator containing HTH domain
HHJ45_03235	COG1902	pentaerythritol trinitrate reductase activity
HHJ45_03235	COG0446	pyridine nucleotide-disulphide oxidoreductase
HHJ45_03240	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HHJ45_03240	COG3408	Glycogen debranching enzyme
HHJ45_03250	COG0531	amino acid
HHJ45_03255	COG2731	YhcH YjgK YiaL family protein
HHJ45_03260	COG3250	beta-galactosidase activity
HHJ45_03265	COG1609	Transcriptional regulator
HHJ45_03270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHJ45_03280	COG0840	transmembrane signaling receptor activity
HHJ45_03285	COG1695	Transcriptional regulator
HHJ45_03290	COG2375	cellular response to nickel ion
HHJ45_03305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ45_03310	COG0358	DNA primase activity
HHJ45_03315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HHJ45_03325	COG0471	metal ion transport
HHJ45_03330	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_03335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_03340	COG0583	DNA-binding transcription factor activity
HHJ45_03350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHJ45_03365	COG4991	sh3 domain protein
HHJ45_03370	COG3025	triphosphatase activity
HHJ45_03395	COG2268	Band 7 protein
HHJ45_03400	COG1585	Membrane protein implicated in regulation of membrane protease activity
HHJ45_03420	COG3121	Chaperone
HHJ45_03430	COG3188	usher protein
HHJ45_03435	COG3188	usher protein
HHJ45_03440	COG3188	usher protein
HHJ45_03450	COG2960	long-chain fatty acid transporting porin activity
HHJ45_03470	COG3384	dioxygenase
HHJ45_03475	COG0754	glutathionylspermidine amidase activity
HHJ45_03485	COG1538	Outer membrane efflux protein
HHJ45_03490	COG0494	nUDIX hydrolase
HHJ45_03495	COG3151	Protein conserved in bacteria
HHJ45_03500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HHJ45_03505	COG3150	esterase
HHJ45_03510	COG0187	DNA topoisomerase II activity
HHJ45_03530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_03550	COG2211	Major facilitator Superfamily
HHJ45_03555	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HHJ45_03560	COG2249	NAD(P)H dehydrogenase (quinone) activity
HHJ45_03570	COG0642	Histidine kinase
HHJ45_03575	COG0745	RESPONSE REGULATOR receiver
HHJ45_03580	COG3111	PFAM Bacterial OB fold (BOF) protein
HHJ45_03585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HHJ45_03590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHJ45_03595	COG0204	Acyl-transferase
HHJ45_03600	COG2132	Multicopper oxidase
HHJ45_03605	COG1032	radical SAM domain protein
HHJ45_03610	COG4238	major outer membrane lipoprotein
HHJ45_03620	COG0656	L-ascorbic acid biosynthetic process
HHJ45_03625	COG1979	alcohol dehydrogenase
HHJ45_03630	COG2207	Transcriptional regulator
HHJ45_03635	COG0586	Pfam SNARE associated Golgi protein
HHJ45_03640	COG0626	cystathionine gamma-synthase activity
HHJ45_03645	COG0811	peptide transport
HHJ45_03650	COG0848	biopolymer transport protein
HHJ45_03655	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_03665	COG0667	Aldo Keto reductase
HHJ45_03680	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HHJ45_03685	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_03690	COG5557	Pfam Polysulphide reductase, NrfD
HHJ45_03695	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HHJ45_03700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ45_03705	COG1773	rubredoxin
HHJ45_03710	COG0375	protein maturation
HHJ45_03715	COG0298	carbon dioxide binding
HHJ45_03725	COG0625	glutathione transferase activity
HHJ45_03730	COG0754	glutathionylspermidine amidase activity
HHJ45_03735	COG0306	phosphate transporter
HHJ45_03740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ45_03745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ45_03750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ45_03755	COG2244	polysaccharide biosynthetic process
HHJ45_03765	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HHJ45_03770	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ45_03780	COG0156	8-amino-7-oxononanoate synthase activity
HHJ45_03785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHJ45_03795	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ45_03800	COG0456	acetyltransferase
HHJ45_03805	COG2186	Transcriptional regulator
HHJ45_03810	COG0277	FAD linked oxidase domain protein
HHJ45_03815	COG0277	FAD linked oxidase domain protein
HHJ45_03820	COG0247	lactate metabolic process
HHJ45_03825	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HHJ45_03830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHJ45_03835	COG1620	l-lactate permease
HHJ45_03840	COG3064	Membrane
HHJ45_03865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHJ45_03870	COG1459	type II secretion system
HHJ45_03875	COG2165	general secretion pathway protein
HHJ45_03890	COG4795	General secretion pathway protein
HHJ45_03905	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HHJ45_03940	COG2003	Belongs to the UPF0758 family
HHJ45_03965	COG2378	regulation of single-species biofilm formation
HHJ45_03970	COG3596	GTP binding
HHJ45_04060	COG3436	PFAM IS66 Orf2 family protein
HHJ45_04070	COG1484	DNA-dependent DNA replication
HHJ45_04075	COG4584	PFAM Integrase catalytic
HHJ45_04095	COG2207	Transcriptional regulator
HHJ45_04095	COG3708	Transcriptional regulator
HHJ45_04100	COG0589	response to stress
HHJ45_04110	COG4372	Transposase
HHJ45_04185	COG1475	DNA binding
HHJ45_04205	COG1201	RNA secondary structure unwinding
HHJ45_04240	COG0582	viral genome integration into host DNA
HHJ45_04250	COG1811	Na channel or pump
HHJ45_04255	COG1982	Orn Lys Arg decarboxylase major
HHJ45_04260	COG2211	Major facilitator Superfamily
HHJ45_04275	COG1194	a g-specific adenine glycosylase
HHJ45_04285	COG3171	Protein conserved in bacteria
HHJ45_04295	COG0252	asparaginase activity
HHJ45_04305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HHJ45_04320	COG0762	integral membrane protein
HHJ45_04325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHJ45_04330	COG2805	Type II/IV secretion system protein
HHJ45_04350	COG0189	ligase activity
HHJ45_04355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HHJ45_04360	COG2356	endonuclease I
HHJ45_04370	COG2814	Major facilitator Superfamily
HHJ45_04390	COG1166	arginine decarboxylase activity
HHJ45_04405	COG0501	Belongs to the peptidase M48B family
HHJ45_04410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHJ45_04415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_04420	COG2213	PTS system mannitol-specific
HHJ45_04425	COG1063	alcohol dehydrogenase
HHJ45_04430	COG1494	fructose-1,6-bisphosphatase
HHJ45_04445	COG1122	ATPase activity
HHJ45_04450	COG1122	ATPase activity
HHJ45_04480	COG0191	fructose-bisphosphate aldolase activity
HHJ45_04485	COG0668	transmembrane transport
HHJ45_04495	COG2968	Membrane
HHJ45_04500	COG0583	DNA-binding transcription factor activity
HHJ45_04505	COG0427	acetyl-CoA hydrolase
HHJ45_04510	COG1024	Enoyl-CoA hydratase
HHJ45_04515	COG1703	isobutyryl-CoA mutase activity
HHJ45_04520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HHJ45_04520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HHJ45_04540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HHJ45_04555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHJ45_04575	COG0006	proline dipeptidase activity
HHJ45_04580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ45_04585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ45_04610	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_04615	COG2723	6-phospho-beta-galactosidase activity
HHJ45_04625	COG1272	protein, Hemolysin III
HHJ45_04635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HHJ45_04645	COG0716	FMN binding
HHJ45_04650	COG4974	Belongs to the 'phage' integrase family
HHJ45_04655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HHJ45_04660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HHJ45_04690	COG2233	PERMEase
HHJ45_04700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_04705	COG2252	PERMEase
HHJ45_04710	COG0402	S-adenosylhomocysteine deaminase activity
HHJ45_04715	COG2233	PERMEase
HHJ45_04720	COG2080	2 iron, 2 sulfur cluster binding
HHJ45_04720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HHJ45_04725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HHJ45_04730	COG0402	S-adenosylhomocysteine deaminase activity
HHJ45_04735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_04735	COG0493	'glutamate synthase
HHJ45_04740	COG2068	MobA-Related Protein
HHJ45_04745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHJ45_04750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHJ45_04750	COG3608	succinylglutamate desuccinylase aspartoacylase
HHJ45_04755	COG0549	Belongs to the carbamate kinase family
HHJ45_04765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HHJ45_04770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ45_04775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHJ45_04785	COG2080	2 iron, 2 sulfur cluster binding
HHJ45_04790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HHJ45_04795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HHJ45_04800	COG4942	peptidase
HHJ45_04810	COG3387	PFAM Glycoside hydrolase 15-related
HHJ45_04950	COG0814	amino acid
HHJ45_04955	COG0183	Belongs to the thiolase family
HHJ45_04965	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_04970	COG2814	Major facilitator Superfamily
HHJ45_04975	COG1794	racemase activity, acting on amino acids and derivatives
HHJ45_04980	COG0583	DNA-binding transcription factor activity
HHJ45_04990	COG1609	Transcriptional regulator
HHJ45_05005	COG0667	Aldo Keto reductase
HHJ45_05015	COG0861	Integral membrane protein TerC family
HHJ45_05030	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HHJ45_05045	COG2165	general secretion pathway protein
HHJ45_05050	COG4795	General secretion pathway protein
HHJ45_05060	COG4967	type IV pilus modification protein PilV
HHJ45_05065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HHJ45_05070	COG1025	Belongs to the peptidase M16 family
HHJ45_05075	COG1074	ATP-dependent DNA helicase activity
HHJ45_05080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HHJ45_05085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HHJ45_05085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHJ45_05090	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ45_05105	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HHJ45_05110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HHJ45_05115	COG2166	iron-sulfur cluster assembly
HHJ45_05120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHJ45_05130	COG0583	DNA-binding transcription factor activity
HHJ45_05135	COG2363	Small membrane protein
HHJ45_05145	COG1349	DNA-binding transcription factor activity
HHJ45_05155	COG1070	Carbohydrate kinase
HHJ45_05165	COG0738	Major facilitator superfamily
HHJ45_05170	COG0235	Class ii aldolase
HHJ45_05175	COG1454	alcohol dehydrogenase
HHJ45_05185	COG1760	l-serine dehydratase
HHJ45_05190	COG0814	amino acid
HHJ45_05195	COG1611	Belongs to the LOG family
HHJ45_05210	COG3098	single-species biofilm formation
HHJ45_05215	COG0564	pseudouridine synthase activity
HHJ45_05220	COG0716	FMN binding
HHJ45_05225	COG2271	Major facilitator Superfamily
HHJ45_05230	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ45_05235	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ45_05240	COG4999	Histidine kinase
HHJ45_05240	COG3850	Histidine kinase
HHJ45_05240	COG3437	response regulator, receiver
HHJ45_05240	COG2205	protein histidine kinase activity
HHJ45_05250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHJ45_05255	COG2336	PFAM SpoVT AbrB
HHJ45_05260	COG2337	Toxic component of a toxin-antitoxin (TA) module
HHJ45_05265	COG3956	TIGRFAM MazG family protein
HHJ45_05285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ45_05295	COG0602	queuosine metabolic process
HHJ45_05300	COG1070	Carbohydrate kinase
HHJ45_05305	COG0720	synthase
HHJ45_05330	COG1203	CRISPR-associated helicase, Cas3
HHJ45_05345	COG1857	crispr-associated protein
HHJ45_05360	COG1518	maintenance of DNA repeat elements
HHJ45_05365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ45_05370	COG2234	aminopeptidase activity
HHJ45_05425	COG4942	peptidase
HHJ45_05425	COG1388	LysM domain
HHJ45_05430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ45_05445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HHJ45_05455	COG2610	gluconate transmembrane transporter activity
HHJ45_05460	COG3622	Belongs to the hyi family
HHJ45_05465	COG0235	Class ii aldolase
HHJ45_05470	COG3395	kinase activity
HHJ45_05475	COG2084	Dehydrogenase
HHJ45_05480	COG1349	DNA-binding transcription factor activity
HHJ45_05485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HHJ45_05595	COG3604	Transcriptional regulator
HHJ45_05600	COG0309	Hydrogenase expression formation protein (HypE)
HHJ45_05605	COG0409	Hydrogenase expression formation protein
HHJ45_05610	COG0298	carbon dioxide binding
HHJ45_05615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HHJ45_05620	COG0375	protein maturation
HHJ45_05630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_05635	COG0651	ATP synthesis coupled electron transport
HHJ45_05640	COG0650	Formate hydrogenlyase subunit 4
HHJ45_05645	COG3261	NADH dehydrogenase
HHJ45_05645	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HHJ45_05650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ45_05655	COG3260	NADH ubiquinone oxidoreductase 20
HHJ45_05665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ45_05670	COG2723	6-phospho-beta-galactosidase activity
HHJ45_05675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_05675	COG1263	PTS System
HHJ45_05680	COG1609	Transcriptional regulator
HHJ45_05685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_05690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HHJ45_05715	COG1349	DNA-binding transcription factor activity
HHJ45_05720	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_05725	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_05735	COG3732	PTS system glucitol sorbitol-specific
HHJ45_05740	COG3730	PTS system glucitol sorbitol-specific
HHJ45_05745	COG2951	lytic endotransglycosylase activity
HHJ45_05750	COG1546	Belongs to the CinA family
HHJ45_05770	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHJ45_05800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ45_05805	COG1238	metal cluster binding
HHJ45_05820	COG2814	Major facilitator Superfamily
HHJ45_05825	COG1566	PFAM secretion protein HlyD family protein
HHJ45_05830	COG1846	Transcriptional regulator
HHJ45_05845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HHJ45_05850	COG2814	Major facilitator Superfamily
HHJ45_05855	COG2113	Glycine betaine
HHJ45_05860	COG4176	ABC-type proline glycine betaine transport system permease component
HHJ45_05865	COG4175	Glycine betaine
HHJ45_05870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ45_05875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ45_05885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ45_05890	COG4575	ribosome binding
HHJ45_05905	COG2916	Histone family protein nucleoid-structuring protein H-NS
HHJ45_05910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ45_05915	COG0640	Transcriptional regulator
HHJ45_05920	COG0401	homolog of Blt101
HHJ45_05925	COG1652	LysM domain
HHJ45_05930	COG1802	Transcriptional regulator
HHJ45_05935	COG1113	amino acid transport
HHJ45_05940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHJ45_05945	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_05950	COG0579	oxidoreductase
HHJ45_06010	COG0582	viral genome integration into host DNA
HHJ45_06025	COG2867	negative regulation of translational initiation
HHJ45_06035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ45_06040	COG0497	DNA recombination
HHJ45_06055	COG4536	flavin adenine dinucleotide binding
HHJ45_06060	COG4137	Cytochrome C assembly protein
HHJ45_06065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHJ45_06090	COG2885	chlorophyll binding
HHJ45_06095	COG2199	diguanylate cyclase activity
HHJ45_06110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ45_06115	COG0287	Prephenate dehydrogenase
HHJ45_06115	COG1605	Chorismate mutase
HHJ45_06120	COG0077	Prephenate dehydratase
HHJ45_06120	COG1605	Chorismate mutase
HHJ45_06130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHJ45_06135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ45_06140	COG0564	pseudouridine synthase activity
HHJ45_06150	COG0542	response to heat
HHJ45_06175	COG0477	Major facilitator Superfamily
HHJ45_06180	COG5544	Lipoprotein
HHJ45_06185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ45_06190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ45_06190	COG0045	succinate-CoA ligase (ADP-forming) activity
HHJ45_06190	COG1042	CoA-binding domain protein
HHJ45_06200	COG3118	belongs to the thioredoxin family
HHJ45_06205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ45_06225	COG0583	DNA-binding transcription factor activity
HHJ45_06230	COG0513	Belongs to the DEAD box helicase family
HHJ45_06240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHJ45_06250	COG1595	DNA-templated transcription, initiation
HHJ45_06255	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HHJ45_06260	COG3026	antisigma factor binding
HHJ45_06265	COG3086	response to oxidative stress
HHJ45_06275	COG0681	Belongs to the peptidase S26 family
HHJ45_06295	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HHJ45_06310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_06315	COG1737	Transcriptional regulator
HHJ45_06320	COG0560	Phosphoserine phosphatase
HHJ45_06340	COG2205	protein histidine kinase activity
HHJ45_06345	COG3170	Tfp pilus assembly protein FimV
HHJ45_06350	COG2204	response regulator
HHJ45_06355	COG0347	Belongs to the P(II) protein family
HHJ45_06360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ45_06360	COG1017	nitric oxide dioxygenase activity
HHJ45_06370	COG1940	carbohydrate kinase activity
HHJ45_06380	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_06385	COG1129	ABC transporter
HHJ45_06390	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_06395	COG1063	alcohol dehydrogenase
HHJ45_06400	COG2017	converts alpha-aldose to the beta-anomer
HHJ45_06405	COG2259	Doxx family
HHJ45_06430	COG4638	Rieske (2fe-2S)
HHJ45_06435	COG0583	DNA-binding transcription factor activity
HHJ45_06440	COG2814	Major facilitator Superfamily
HHJ45_06445	COG3711	transcriptional antiterminator
HHJ45_06450	COG1073	alpha beta
HHJ45_06455	COG0483	inositol monophosphate 1-phosphatase activity
HHJ45_06475	COG0822	iron-sulfur transferase activity
HHJ45_06495	COG0633	Ferredoxin
HHJ45_06500	COG2975	iron-sulfur cluster assembly
HHJ45_06515	COG2897	thiosulfate sulfurtransferase activity
HHJ45_06520	COG2373	Large extracellular alpha-helical protein
HHJ45_06525	COG4953	penicillin-binding protein 1C
HHJ45_06555	COG2976	Protein conserved in bacteria
HHJ45_06570	COG1645	bacterial-type flagellum-dependent swarming motility
HHJ45_06580	COG0517	IMP dehydrogenase activity
HHJ45_06580	COG0516	GMP reductase activity
HHJ45_06595	COG3133	Outer membrane lipoprotein
HHJ45_06610	COG2200	EAL domain
HHJ45_06615	COG0248	Ppx GppA phosphatase
HHJ45_06620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHJ45_06625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHJ45_06640	COG2233	PERMEase
HHJ45_06650	COG1393	Belongs to the ArsC family
HHJ45_06655	COG4783	chaperone-mediated protein folding
HHJ45_06660	COG0628	permease
HHJ45_06685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ45_06690	COG3261	NADH dehydrogenase
HHJ45_06690	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HHJ45_06695	COG0651	ATP synthesis coupled electron transport
HHJ45_06700	COG4237	Hydrogenase 4 membrane
HHJ45_06710	COG0650	Formate hydrogenlyase subunit 4
HHJ45_06715	COG0651	ATP synthesis coupled electron transport
HHJ45_06720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_06725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHJ45_06730	COG2716	regulation of RNA biosynthetic process
HHJ45_06740	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HHJ45_06760	COG2321	neutral zinc metallopeptidase
HHJ45_06770	COG0400	carboxylic ester hydrolase activity
HHJ45_06785	COG1393	Belongs to the ArsC family
HHJ45_06795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ45_06800	COG3850	Histidine kinase
HHJ45_06805	COG0493	'glutamate synthase
HHJ45_06805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_06815	COG5342	invasion associated locus B
HHJ45_06820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHJ45_06825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ45_06830	COG0280	phosphate acetyltransferase
HHJ45_06830	COG0281	malic enzyme
HHJ45_06835	COG4810	utilization protein
HHJ45_06840	COG4917	ethanolamine utilization protein
HHJ45_06845	COG4766	ethanolamine catabolic process
HHJ45_06850	COG4812	Cobalamin adenosyltransferase
HHJ45_06855	COG0280	phosphate acetyltransferase
HHJ45_06860	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HHJ45_06865	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HHJ45_06870	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_06875	COG4820	ethanolamine utilization protein (EutJ)
HHJ45_06880	COG1454	alcohol dehydrogenase
HHJ45_06885	COG3192	ethanolamine utilization protein
HHJ45_06890	COG4819	ethanolamine utilization protein
HHJ45_06895	COG4303	Ethanolamine ammonia lyase large subunit
HHJ45_06905	COG4816	utilization protein
HHJ45_06910	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HHJ45_06915	COG2207	Transcriptional regulator
HHJ45_06925	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ45_06945	COG2837	iron assimilation
HHJ45_06950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HHJ45_06955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_06955	COG1263	PTS System
HHJ45_06970	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_06975	COG4150	thiosulfate binding
HHJ45_06980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HHJ45_06985	COG4208	sulfate ABC transporter
HHJ45_06990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HHJ45_06995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HHJ45_07010	COG2190	(PTS) system
HHJ45_07015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ45_07020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_07025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HHJ45_07045	COG3530	Putative quorum-sensing-regulated virulence factor
HHJ45_07050	COG0385	Bile acid
HHJ45_07055	COG0583	DNA-binding transcription factor activity
HHJ45_07065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHJ45_07070	COG2211	Major facilitator Superfamily
HHJ45_07080	COG0583	DNA-binding transcription factor activity
HHJ45_07120	COG3415	Transposase
HHJ45_07125	COG3415	Transposase
HHJ45_07140	COG2200	EAL domain
HHJ45_07140	COG2199	diguanylate cyclase activity
HHJ45_07145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHJ45_07170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_07175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_07180	COG0006	proline dipeptidase activity
HHJ45_07185	COG1363	Peptidase, m42
HHJ45_07195	COG2207	Transcriptional regulator
HHJ45_07200	COG3279	Response regulator of the LytR AlgR family
HHJ45_07205	COG3275	phosphorelay sensor kinase activity
HHJ45_07210	COG0436	Aminotransferase
HHJ45_07220	COG1560	Kdo2-lipid A biosynthetic process
HHJ45_07245	COG0028	Belongs to the TPP enzyme family
HHJ45_07250	COG0679	Auxin Efflux Carrier
HHJ45_07255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HHJ45_07260	COG2205	protein histidine kinase activity
HHJ45_07260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_07260	COG0784	Response regulator, receiver
HHJ45_07260	COG2198	Histidine kinase
HHJ45_07265	COG2197	response regulator
HHJ45_07270	COG1566	PFAM secretion protein HlyD family protein
HHJ45_07275	COG0477	Major facilitator Superfamily
HHJ45_07355	COG3723	Recombinational DNA repair protein, rece pathway
HHJ45_07490	COG1783	phage Terminase large subunit
HHJ45_07495	COG3567	Phage-associated protein, HI1409 family
HHJ45_07635	COG0582	viral genome integration into host DNA
HHJ45_07645	COG2116	formate transmembrane transporter activity
HHJ45_07650	COG2853	Lipoprotein
HHJ45_07665	COG2067	long-chain fatty acid transport protein
HHJ45_07670	COG3691	Protein conserved in bacteria
HHJ45_07685	COG2062	phosphohistidine phosphatase, SixA
HHJ45_07690	COG3539	Fimbrial protein
HHJ45_07695	COG3188	usher protein
HHJ45_07700	COG3121	Chaperone
HHJ45_07705	COG3539	Fimbrial protein
HHJ45_07710	COG3539	Fimbrial protein
HHJ45_07715	COG3539	Fimbrial protein
HHJ45_07745	COG0730	response to heat
HHJ45_07750	COG3101	peptidyl-lysine hydroxylation
HHJ45_07765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HHJ45_07770	COG2814	Major facilitator Superfamily
HHJ45_07785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHJ45_07795	COG0586	Pfam SNARE associated Golgi protein
HHJ45_07805	COG0285	dihydrofolate synthase activity
HHJ45_07810	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HHJ45_07815	COG1286	toxin biosynthetic process
HHJ45_07820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHJ45_07825	COG0163	prenyltransferase activity
HHJ45_07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_07835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_07840	COG4215	(ABC) transporter
HHJ45_07845	COG4160	amino acid transport
HHJ45_07850	COG4598	ABC transporter
HHJ45_07855	COG5464	transposase or invertase
HHJ45_07860	COG1090	epimerase
HHJ45_07865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHJ45_07870	COG0625	glutathione transferase activity
HHJ45_07875	COG0625	glutathione transferase activity
HHJ45_07880	COG0622	Phosphoesterase
HHJ45_07885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HHJ45_07890	COG1288	antiporter activity
HHJ45_07895	COG0857	belongs to the CobB CobQ family
HHJ45_07895	COG0280	phosphate acetyltransferase
HHJ45_07900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHJ45_07915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ45_07920	COG0490	domain, Protein
HHJ45_07920	COG0471	metal ion transport
HHJ45_07930	COG0436	Aminotransferase
HHJ45_07935	COG0583	DNA-binding transcription factor activity
HHJ45_07955	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HHJ45_07960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HHJ45_07965	COG1034	ATP synthesis coupled electron transport
HHJ45_07980	COG0839	Belongs to the complex I subunit 6 family
HHJ45_07990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HHJ45_07995	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ45_08025	COG2153	protein acetylation
HHJ45_08030	COG4575	ribosome binding
HHJ45_08035	COG1169	isochorismate synthase
HHJ45_08050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHJ45_08060	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ45_08130	COG5464	transposase or invertase
HHJ45_08135	COG0247	lactate metabolic process
HHJ45_08145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHJ45_08150	COG2271	Major facilitator Superfamily
HHJ45_08155	COG0584	glycerophosphoryl diester phosphodiesterase
HHJ45_08165	COG3642	lipopolysaccharide core region biosynthetic process
HHJ45_08170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ45_08175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ45_08180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ45_08200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHJ45_08205	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HHJ45_08210	COG3234	Protein of unknown function (DUF1175)
HHJ45_08215	COG2373	Large extracellular alpha-helical protein
HHJ45_08220	COG5445	Predicted secreted protein (DUF2300)
HHJ45_08225	COG4676	Protein conserved in bacteria
HHJ45_08230	COG0784	Response regulator, receiver
HHJ45_08230	COG2205	protein histidine kinase activity
HHJ45_08235	COG2197	response regulator
HHJ45_08240	COG2198	Histidine kinase
HHJ45_08240	COG0642	Histidine kinase
HHJ45_08250	COG1477	protein flavinylation
HHJ45_08255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHJ45_08255	COG2169	Transcriptional regulator
HHJ45_08260	COG3145	DNA-N1-methyladenine dioxygenase activity
HHJ45_08265	COG4615	Cyclic peptide transporter
HHJ45_08285	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_08285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ45_08290	COG3062	negative regulation of establishment of protein localization
HHJ45_08300	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_08305	COG0348	domain, Protein
HHJ45_08310	COG3043	anaerobic respiration
HHJ45_08315	COG3005	denitrification pathway
HHJ45_08320	COG4133	protoheme IX ABC transporter activity
HHJ45_08325	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ45_08330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ45_08335	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ45_08345	COG1138	Cytochrome C-type biogenesis protein
HHJ45_08350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HHJ45_08355	COG3088	subunit of a heme lyase
HHJ45_08355	COG4235	cytochrome complex assembly
HHJ45_08360	COG2197	response regulator
HHJ45_08375	COG3083	sulfuric ester hydrolase activity
HHJ45_08395	COG1061	Type III restriction enzyme res subunit
HHJ45_08400	COG1187	pseudouridine synthase activity
HHJ45_08405	COG2814	Major facilitator Superfamily
HHJ45_08415	COG4172	Belongs to the ABC transporter superfamily
HHJ45_08420	COG4239	(ABC) transporter, permease
HHJ45_08425	COG4174	ABC transporter (Permease)
HHJ45_08430	COG4166	transmembrane transport
HHJ45_08435	COG2200	EAL domain
HHJ45_08440	COG0791	NLP P60 protein
HHJ45_08445	COG0671	phosphoesterase, PA-phosphatase related
HHJ45_08450	COG0523	cobalamin synthesis protein
HHJ45_08455	COG0246	Mannitol dehydrogenase
HHJ45_08470	COG2814	Major facilitator Superfamily
HHJ45_08475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_08475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_08480	COG1105	Belongs to the carbohydrate kinase PfkB family
HHJ45_08485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_08485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HHJ45_08485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_08495	COG2313	pseudouridylate synthase activity
HHJ45_08500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHJ45_08505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ45_08515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHJ45_08520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_08520	COG1522	sequence-specific DNA binding
HHJ45_08530	COG2855	membrane
HHJ45_08535	COG0583	DNA-binding transcription factor activity
HHJ45_08540	COG0833	amino acid
HHJ45_08545	COG4771	TonB-dependent receptor
HHJ45_08560	COG2311	Membrane
HHJ45_08565	COG1609	Transcriptional regulator
HHJ45_08570	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_08575	COG1129	ABC transporter
HHJ45_08580	COG4211	Belongs to the binding-protein-dependent transport system permease family
HHJ45_08585	COG0167	dihydroorotate dehydrogenase activity
HHJ45_08585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HHJ45_08590	COG0493	'glutamate synthase
HHJ45_08600	COG2949	membrane
HHJ45_08610	COG1346	cytolysis
HHJ45_08620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ45_08635	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_08640	COG0586	Pfam SNARE associated Golgi protein
HHJ45_08650	COG1686	Belongs to the peptidase S11 family
HHJ45_08655	COG0277	FAD linked oxidase domain protein
HHJ45_08660	COG1472	Belongs to the glycosyl hydrolase 3 family
HHJ45_08665	COG1732	Glycine betaine
HHJ45_08670	COG1174	glycine betaine transport
HHJ45_08675	COG1125	glycine betaine transport
HHJ45_08680	COG1174	glycine betaine transport
HHJ45_08695	COG3275	phosphorelay sensor kinase activity
HHJ45_08700	COG3279	Response regulator of the LytR AlgR family
HHJ45_08705	COG4807	Protein conserved in bacteria
HHJ45_08710	COG4808	Protein conserved in bacteria
HHJ45_08715	COG4715	Zinc finger, swim domain protein
HHJ45_08720	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HHJ45_08725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HHJ45_08730	COG0714	Associated with various cellular activities
HHJ45_08740	COG3831	ATPase activity
HHJ45_08745	COG3831	ATPase activity
HHJ45_08755	COG0489	protein tyrosine kinase activity
HHJ45_08765	COG3539	Fimbrial protein
HHJ45_08770	COG3121	Chaperone
HHJ45_08775	COG3188	usher protein
HHJ45_08780	COG3539	Fimbrial protein
HHJ45_08785	COG5455	response to cobalt ion
HHJ45_08805	COG0351	phosphomethylpyrimidine kinase
HHJ45_08810	COG3757	hydrolase, family 25
HHJ45_08815	COG2188	Transcriptional regulator
HHJ45_08820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_08825	COG1397	ADP-ribosylglycohydrolase
HHJ45_08830	COG2211	Major facilitator Superfamily
HHJ45_08835	COG1830	Aldolase
HHJ45_08850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_08855	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ45_08860	COG3775	system Galactitol-specific IIC component
HHJ45_08865	COG1063	alcohol dehydrogenase
HHJ45_08895	COG0745	RESPONSE REGULATOR receiver
HHJ45_08900	COG2205	protein histidine kinase activity
HHJ45_08935	COG4245	von Willebrand factor, type A
HHJ45_08940	COG0631	protein serine/threonine phosphatase activity
HHJ45_08945	COG3779	Protein conserved in bacteria
HHJ45_08950	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HHJ45_08955	COG0443	Heat shock 70 kDa protein
HHJ45_08960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHJ45_08970	COG0572	uridine kinase
HHJ45_08980	COG2982	Protein involved in outer membrane biogenesis
HHJ45_08985	COG1253	flavin adenine dinucleotide binding
HHJ45_09050	COG0463	Glycosyl transferase, family 2
HHJ45_09070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ45_09080	COG0297	glycogen (starch) synthase activity
HHJ45_09140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HHJ45_09150	COG0438	transferase activity, transferring glycosyl groups
HHJ45_09160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHJ45_09160	COG0140	phosphoribosyl-ATP diphosphatase activity
HHJ45_09175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHJ45_09180	COG0131	Imidazoleglycerol-phosphate dehydratase
HHJ45_09180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HHJ45_09205	COG2161	toxin-antitoxin pair type II binding
HHJ45_09210	COG4115	mRNA cleavage
HHJ45_09215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ45_09220	COG0583	DNA-binding transcription factor activity
HHJ45_09230	COG0531	amino acid
HHJ45_09240	COG0425	Belongs to the sulfur carrier protein TusA family
HHJ45_09245	COG2925	Exonuclease
HHJ45_09250	COG1686	Belongs to the peptidase S11 family
HHJ45_09260	COG1289	transmembrane transporter activity
HHJ45_09305	COG2003	Belongs to the UPF0758 family
HHJ45_09410	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HHJ45_09450	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HHJ45_09465	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ45_09475	COG0583	DNA-binding transcription factor activity
HHJ45_09480	COG0583	DNA-binding transcription factor activity
HHJ45_09490	COG0534	Mate efflux family protein
HHJ45_09500	COG0217	transcriptional regulatory protein
HHJ45_09505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHJ45_09510	COG0477	Major facilitator Superfamily
HHJ45_09520	COG1470	cell adhesion involved in biofilm formation
HHJ45_09520	COG1388	LysM domain
HHJ45_09525	COG1388	LysM domain
HHJ45_09525	COG1470	cell adhesion involved in biofilm formation
HHJ45_09530	COG1388	LysM domain
HHJ45_09530	COG2373	Large extracellular alpha-helical protein
HHJ45_09530	COG4932	domain protein
HHJ45_09535	COG4771	TonB-dependent receptor
HHJ45_09540	COG1021	2,3-dihydroxybenzoate-AMP ligase
HHJ45_09560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HHJ45_09560	COG3433	isochorismatase activity
HHJ45_09560	COG2226	methyltransferase
HHJ45_09575	COG1132	(ABC) transporter
HHJ45_09580	COG2814	Major facilitator Superfamily
HHJ45_09585	COG1169	isochorismate synthase
HHJ45_09590	COG0582	viral genome integration into host DNA
HHJ45_09665	COG1846	Transcriptional regulator
HHJ45_09675	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HHJ45_09680	COG1403	HNH endonuclease
HHJ45_09745	COG1802	Transcriptional regulator
HHJ45_09745	COG4626	Terminase
HHJ45_09750	COG4695	Portal protein
HHJ45_09755	COG0740	serine-type endopeptidase activity
HHJ45_09870	COG3443	Belongs to the bacterial solute-binding protein 9 family
HHJ45_09875	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HHJ45_09885	COG2351	hydroxyisourate hydrolase activity
HHJ45_09890	COG0745	RESPONSE REGULATOR receiver
HHJ45_09895	COG2205	protein histidine kinase activity
HHJ45_09905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ45_09915	COG1418	mRNA catabolic process
HHJ45_09920	COG0270	DNA (cytosine-5-)-methyltransferase activity
HHJ45_09925	COG3727	T/G mismatch-specific endonuclease activity
HHJ45_09930	COG0697	spore germination
HHJ45_09935	COG2354	Protein conserved in bacteria
HHJ45_09940	COG5475	Uncharacterized small protein (DUF2158)
HHJ45_09965	COG2197	response regulator
HHJ45_09970	COG1684	flagellar biosynthetic protein fliR
HHJ45_09975	COG1987	bacterial-type flagellum assembly
HHJ45_09980	COG1338	Plays a role in the flagellum-specific transport system
HHJ45_09985	COG3190	flagellar
HHJ45_09990	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ45_09995	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ45_10000	COG1580	Controls the rotational direction of flagella during chemotaxis
HHJ45_10005	COG3144	bacterial-type flagellum assembly
HHJ45_10010	COG2882	bacterial-type flagellum organization
HHJ45_10015	COG1157	protein secretion by the type III secretion system
HHJ45_10025	COG1317	bacterial-type flagellum organization
HHJ45_10030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ45_10035	COG1766	The M ring may be actively involved in energy transduction
HHJ45_10045	COG2135	peptidase activity
HHJ45_10050	COG0425	Belongs to the sulfur carrier protein TusA family
HHJ45_10055	COG2391	methyltransferase activity
HHJ45_10065	COG0366	Alpha amylase catalytic
HHJ45_10075	COG1516	flagellar protein fliS
HHJ45_10080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHJ45_10085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHJ45_10090	COG1191	sigma factor activity
HHJ45_10120	COG2197	response regulator
HHJ45_10135	COG2197	response regulator
HHJ45_10165	COG3318	Belongs to the UPF0149 family
HHJ45_10165	COG3012	SEC-C Motif Domain Protein
HHJ45_10170	COG0814	amino acid
HHJ45_10180	COG1528	Iron-storage protein
HHJ45_10200	COG1528	Iron-storage protein
HHJ45_10205	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_10210	COG1129	ABC transporter
HHJ45_10215	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_10220	COG1877	trehalose-phosphatase activity
HHJ45_10230	COG0589	response to stress
HHJ45_10245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HHJ45_10250	COG1360	Flagellar Motor Protein
HHJ45_10255	COG0643	Histidine kinase
HHJ45_10255	COG2198	Histidine kinase
HHJ45_10260	COG0835	chemotaxis
HHJ45_10265	COG0840	transmembrane signaling receptor activity
HHJ45_10270	COG0840	transmembrane signaling receptor activity
HHJ45_10275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HHJ45_10280	COG2201	protein-glutamate methylesterase activity
HHJ45_10285	COG0745	RESPONSE REGULATOR receiver
HHJ45_10290	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HHJ45_10295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHJ45_10300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHJ45_10310	COG3755	Protein conserved in bacteria
HHJ45_10320	COG3102	Protein conserved in bacteria
HHJ45_10330	COG3005	denitrification pathway
HHJ45_10355	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HHJ45_10360	COG1801	Protein of unknown function DUF72
HHJ45_10365	COG1335	isochorismatase
HHJ45_10375	COG0494	nUDIX hydrolase
HHJ45_10380	COG0217	transcriptional regulatory protein
HHJ45_10405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HHJ45_10415	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HHJ45_10420	COG0739	heme binding
HHJ45_10425	COG1560	Kdo2-lipid A biosynthetic process
HHJ45_10430	COG0469	pyruvate kinase activity
HHJ45_10435	COG1737	Transcriptional regulator
HHJ45_10440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHJ45_10445	COG0129	dihydroxy-acid dehydratase activity
HHJ45_10450	COG0800	Aldolase
HHJ45_10460	COG3141	response to X-ray
HHJ45_10470	COG2979	Protein of unknown function (DUF533)
HHJ45_10475	COG1770	oligopeptidase
HHJ45_10480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ45_10485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ45_10495	COG2372	response to copper ion
HHJ45_10500	COG1276	copper resistance
HHJ45_10510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HHJ45_10530	COG3008	intermembrane lipid transfer
HHJ45_10535	COG2995	paraquat-inducible protein a
HHJ45_10540	COG1956	GAF domain-containing protein
HHJ45_10550	COG0793	Belongs to the peptidase S41A family
HHJ45_10560	COG2814	Major facilitator Superfamily
HHJ45_10565	COG1414	Transcriptional regulator
HHJ45_10595	COG2226	methyltransferase
HHJ45_10610	COG3716	PTS system mannose fructose sorbose family IID component
HHJ45_10615	COG3715	PTS system
HHJ45_10620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_10620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_10625	COG1253	flavin adenine dinucleotide binding
HHJ45_10630	COG2200	EAL domain
HHJ45_10635	COG1760	l-serine dehydratase
HHJ45_10645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHJ45_10665	COG0251	oxidation-reduction process
HHJ45_10670	COG1199	ATP-dependent helicase activity
HHJ45_10675	COG1214	PFAM Peptidase M22, glycoprotease
HHJ45_10680	COG3065	identical protein binding
HHJ45_10685	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ45_10690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HHJ45_10695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ45_10700	COG4638	Rieske (2fe-2S)
HHJ45_10705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HHJ45_10710	COG0473	3-isopropylmalate dehydrogenase activity
HHJ45_10715	COG0583	DNA-binding transcription factor activity
HHJ45_10735	COG2261	transglycosylase associated protein
HHJ45_10750	COG2203	Gaf domain
HHJ45_10750	COG2199	diguanylate cyclase activity
HHJ45_10755	COG3042	response to heat
HHJ45_10760	COG3189	MarR family transcriptional regulator
HHJ45_10770	COG2207	Transcriptional regulator
HHJ45_10785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHJ45_10790	COG2199	diguanylate cyclase activity
HHJ45_10805	COG2766	serine protein kinase
HHJ45_10810	COG3713	MltA-interacting MipA family protein
HHJ45_10815	COG0656	L-ascorbic acid biosynthetic process
HHJ45_10820	COG0676	glucose-6-phosphate 1-epimerase activity
HHJ45_10825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HHJ45_10835	COG3139	Protein of unknown function (DUF1315)
HHJ45_10840	COG1335	isochorismatase
HHJ45_10845	COG0252	asparaginase activity
HHJ45_10850	COG0616	signal peptide processing
HHJ45_10855	COG0778	Nitroreductase
HHJ45_10865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHJ45_10875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HHJ45_10885	COG0494	nUDIX hydrolase
HHJ45_10890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHJ45_10895	COG2897	thiosulfate sulfurtransferase activity
HHJ45_10900	COG4136	ATPase activity
HHJ45_10905	COG4135	transport system, permease component
HHJ45_10910	COG4134	Bacterial extracellular solute-binding protein
HHJ45_10915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ45_10920	COG0398	Pfam SNARE associated Golgi protein
HHJ45_10930	COG0398	Pfam SNARE associated Golgi protein
HHJ45_10935	COG0708	Exodeoxyribonuclease III
HHJ45_10965	COG3678	ATP-independent chaperone mediated protein folding
HHJ45_10975	COG0322	excinuclease ABC activity
HHJ45_10985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ45_10990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ45_10995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ45_11000	COG1447	Phosphotransferase system cellobiose-specific component IIA
HHJ45_11005	COG2169	Transcriptional regulator
HHJ45_11005	COG1917	Cupin 2, conserved barrel domain protein
HHJ45_11010	COG1486	melibiose metabolic process
HHJ45_11020	COG0753	catalase activity
HHJ45_11045	COG1988	membrane-bound metal-dependent
HHJ45_11050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ45_11060	COG3001	Fructosamine kinase
HHJ45_11070	COG1105	Belongs to the carbohydrate kinase PfkB family
HHJ45_11075	COG3137	Salt-induced outer membrane protein
HHJ45_11135	COG0386	Belongs to the glutathione peroxidase family
HHJ45_11145	COG0791	NLP P60 protein
HHJ45_11150	COG2200	EAL domain
HHJ45_11160	COG4256	Hemin uptake protein
HHJ45_11165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ45_11175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ45_11175	COG0574	Belongs to the PEP-utilizing enzyme family
HHJ45_11180	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ45_11185	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HHJ45_11190	COG0644	oxidoreductase
HHJ45_11195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HHJ45_11200	COG2086	electron transfer activity
HHJ45_11205	COG1917	Cupin 2, conserved barrel domain protein
HHJ45_11205	COG2207	Transcriptional regulator
HHJ45_11210	COG1960	acyl-CoA dehydrogenase activity
HHJ45_11215	COG4670	ketone body catabolic process
HHJ45_11230	COG2271	Major facilitator Superfamily
HHJ45_11235	COG0738	Major facilitator superfamily
HHJ45_11250	COG0628	permease
HHJ45_11255	COG0247	lactate metabolic process
HHJ45_11255	COG0277	FAD linked oxidase domain protein
HHJ45_11260	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ45_11270	COG0316	Belongs to the HesB IscA family
HHJ45_11275	COG0719	Fe-S assembly protein
HHJ45_11280	COG0396	ATPase activity
HHJ45_11285	COG0719	Fe-S assembly protein
HHJ45_11300	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ45_11305	COG4238	major outer membrane lipoprotein
HHJ45_11310	COG0469	pyruvate kinase activity
HHJ45_11325	COG2414	aldehyde ferredoxin oxidoreductase
HHJ45_11335	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_11340	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HHJ45_11350	COG4529	Protein conserved in bacteria
HHJ45_11370	COG3468	outer membrane autotransporter barrel domain protein
HHJ45_11380	COG0307	riboflavin synthase, alpha
HHJ45_11385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HHJ45_11390	COG2814	Major facilitator Superfamily
HHJ45_11395	COG0583	DNA-binding transcription factor activity
HHJ45_11410	COG2814	Major facilitator Superfamily
HHJ45_11415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHJ45_11420	COG0791	NLP P60 protein
HHJ45_11425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HHJ45_11430	COG1201	RNA secondary structure unwinding
HHJ45_11440	COG0346	lactoylglutathione lyase activity
HHJ45_11445	COG1902	pentaerythritol trinitrate reductase activity
HHJ45_11450	COG1309	transcriptional regulator
HHJ45_11455	COG3313	Fe-S protein
HHJ45_11460	COG4989	oxidoreductase activity
HHJ45_11465	COG2032	superoxide dismutase activity
HHJ45_11470	COG1289	transmembrane transporter activity
HHJ45_11475	COG1566	PFAM secretion protein HlyD family protein
HHJ45_11490	COG3133	Outer membrane lipoprotein
HHJ45_11500	COG3895	Periplasmic Protein
HHJ45_11515	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HHJ45_11520	COG0625	glutathione transferase activity
HHJ45_11525	COG3104	oligopeptide transport
HHJ45_11530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHJ45_11540	COG4659	FMN binding
HHJ45_11580	COG0673	inositol 2-dehydrogenase activity
HHJ45_11590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HHJ45_11595	COG1263	PTS System
HHJ45_11595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_11600	COG1609	Transcriptional regulator
HHJ45_11605	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_11610	COG1309	transcriptional regulator
HHJ45_11615	COG3250	beta-galactosidase activity
HHJ45_11630	COG5339	Protein conserved in bacteria
HHJ45_11635	COG1482	cell wall glycoprotein biosynthetic process
HHJ45_11640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_11640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_11645	COG0114	fumarate hydratase activity
HHJ45_11655	COG2205	protein histidine kinase activity
HHJ45_11660	COG0745	RESPONSE REGULATOR receiver
HHJ45_11665	COG3136	membrane protein required for alginate biosynthesis
HHJ45_11675	COG0531	amino acid
HHJ45_11685	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HHJ45_11690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HHJ45_11695	COG0628	permease
HHJ45_11710	COG3591	Belongs to the peptidase S1B family
HHJ45_11725	COG2814	Major facilitator Superfamily
HHJ45_11730	COG0583	DNA-binding transcription factor activity
HHJ45_11735	COG1940	carbohydrate kinase activity
HHJ45_11740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHJ45_11750	COG3381	protein complex oligomerization
HHJ45_11755	COG3302	dmso reductase anchor subunit
HHJ45_11760	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_11765	COG0243	molybdopterin cofactor binding
HHJ45_11770	COG0243	molybdopterin cofactor binding
HHJ45_11785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ45_11800	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ45_11805	COG1063	alcohol dehydrogenase
HHJ45_11835	COG1802	Transcriptional regulator
HHJ45_11840	COG4221	oxidoreductase activity
HHJ45_11845	COG0339	signal peptide processing
HHJ45_11850	COG1546	Belongs to the CinA family
HHJ45_11855	COG3111	PFAM Bacterial OB fold (BOF) protein
HHJ45_11860	COG3706	GGDEF domain
HHJ45_11870	COG2814	Major facilitator Superfamily
HHJ45_11875	COG0697	spore germination
HHJ45_11880	COG2188	Transcriptional regulator
HHJ45_11890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ45_11895	COG1447	Phosphotransferase system cellobiose-specific component IIA
HHJ45_11905	COG2723	6-phospho-beta-galactosidase activity
HHJ45_11915	COG4977	sequence-specific DNA binding
HHJ45_11920	COG1846	Transcriptional regulator
HHJ45_11940	COG0583	DNA-binding transcription factor activity
HHJ45_11945	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_11950	COG2066	Belongs to the glutaminase family
HHJ45_11960	COG2199	diguanylate cyclase activity
HHJ45_11970	COG3781	membrane
HHJ45_12020	COG2911	Protein conserved in bacteria
HHJ45_12020	COG3210	domain, Protein
HHJ45_12025	COG1396	sequence-specific DNA binding
HHJ45_12030	COG3550	peptidyl-serine autophosphorylation
HHJ45_12040	COG3539	Fimbrial protein
HHJ45_12050	COG3188	usher protein
HHJ45_12055	COG3539	Fimbrial protein
HHJ45_12060	COG3539	Fimbrial protein
HHJ45_12065	COG3539	Fimbrial protein
HHJ45_12070	COG0243	molybdopterin cofactor binding
HHJ45_12085	COG3119	arylsulfatase activity
HHJ45_12090	COG0641	radical SAM
HHJ45_12100	COG4178	(ABC) transporter
HHJ45_12105	COG4771	TonB-dependent receptor
HHJ45_12110	COG0612	Peptidase, M16
HHJ45_12115	COG0076	glutamate decarboxylase activity
HHJ45_12120	COG0531	amino acid
HHJ45_12135	COG2199	diguanylate cyclase activity
HHJ45_12135	COG2202	Pas domain
HHJ45_12135	COG2200	EAL domain
HHJ45_12140	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HHJ45_12145	COG0747	negative chemotaxis
HHJ45_12150	COG0601	transmembrane transport
HHJ45_12155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ45_12160	COG0444	Belongs to the ABC transporter superfamily
HHJ45_12165	COG4608	Belongs to the ABC transporter superfamily
HHJ45_12170	COG1764	response to oxidative stress
HHJ45_12190	COG1064	alcohol dehydrogenase
HHJ45_12195	COG3093	addiction module antidote protein HigA
HHJ45_12200	COG2864	formate dehydrogenase
HHJ45_12205	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_12215	COG0697	spore germination
HHJ45_12220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ45_12230	COG2223	nitrite transmembrane transporter activity
HHJ45_12235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHJ45_12240	COG1140	nitrate reductase beta subunit
HHJ45_12245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HHJ45_12250	COG2181	nitrate reductase activity
HHJ45_12255	COG0384	phenazine biosynthesis protein PhzF
HHJ45_12260	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HHJ45_12265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHJ45_12285	COG3209	COG3209 Rhs family protein
HHJ45_12315	COG3209	COG3209 Rhs family protein
HHJ45_12335	COG1113	amino acid transport
HHJ45_12340	COG3391	amine dehydrogenase activity
HHJ45_12345	COG4772	TonB-dependent receptor
HHJ45_12350	COG1802	Transcriptional regulator
HHJ45_12355	COG2130	NADP-dependent
HHJ45_12360	COG1247	-acetyltransferase
HHJ45_12365	COG3238	Protein conserved in bacteria
HHJ45_12390	COG1177	transmembrane transport
HHJ45_12395	COG1176	ABC-type spermidine putrescine transport system, permease component I
HHJ45_12415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ45_12420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HHJ45_12425	COG1598	PFAM Uncharacterised protein family UPF0150
HHJ45_12430	COG1724	mRNA binding
HHJ45_12440	COG0826	peptidase U32
HHJ45_12445	COG1396	sequence-specific DNA binding
HHJ45_12450	COG3135	benzoate transporter
HHJ45_12455	COG0675	Transposase, IS605 OrfB family
HHJ45_12470	COG0500	methyltransferase
HHJ45_12475	COG1275	C4-dicarboxylate transporter malic acid transport protein
HHJ45_12480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHJ45_12485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ45_12490	COG2841	Protein conserved in bacteria
HHJ45_12500	COG5383	Protein conserved in bacteria
HHJ45_12505	COG0583	DNA-binding transcription factor activity
HHJ45_12510	COG0840	transmembrane signaling receptor activity
HHJ45_12525	COG3038	cytochrome b561
HHJ45_12530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HHJ45_12535	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_12540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HHJ45_12545	COG1643	Atp-dependent helicase
HHJ45_12555	COG2453	phosphatase
HHJ45_12555	COG0671	phosphoesterase, PA-phosphatase related
HHJ45_12560	COG2267	carboxylic ester hydrolase activity
HHJ45_12565	COG4589	Belongs to the CDS family
HHJ45_12570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHJ45_12580	COG0667	Aldo Keto reductase
HHJ45_12585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHJ45_12590	COG3327	negative regulation of DNA-templated transcription, initiation
HHJ45_12595	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HHJ45_12600	COG0183	Belongs to the thiolase family
HHJ45_12605	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ45_12610	COG1250	3-hydroxyacyl-CoA dehydrogenase
HHJ45_12615	COG1024	Enoyl-CoA hydratase
HHJ45_12620	COG1024	Enoyl-CoA hydratase
HHJ45_12625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ45_12630	COG2151	metal-sulfur cluster biosynthetic enzyme
HHJ45_12635	COG3396	Phenylacetate-CoA oxygenase
HHJ45_12640	COG3460	Phenylacetate-CoA oxygenase
HHJ45_12645	COG3396	Phenylacetate-CoA oxygenase
HHJ45_12650	COG2030	dehydratase
HHJ45_12650	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_12655	COG3733	amine oxidase
HHJ45_12660	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_12665	COG2207	Transcriptional regulator
HHJ45_12670	COG3784	Protein of unknown function (DUF1318)
HHJ45_12680	COG2911	Protein conserved in bacteria
HHJ45_12685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHJ45_12690	COG3187	Heat shock protein
HHJ45_12695	COG3042	response to heat
HHJ45_12700	COG1013	pyruvate-flavodoxin oxidoreductase activity
HHJ45_12700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HHJ45_12700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ45_12700	COG0674	pyruvate-flavodoxin oxidoreductase activity
HHJ45_12710	COG0589	response to stress
HHJ45_12720	COG0513	Belongs to the DEAD box helicase family
HHJ45_12730	COG3706	GGDEF domain
HHJ45_12735	COG2840	Smr protein MutS2
HHJ45_12740	COG0583	DNA-binding transcription factor activity
HHJ45_12745	COG1473	amidohydrolase
HHJ45_12750	COG1473	amidohydrolase
HHJ45_12755	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HHJ45_12760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHJ45_12765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ45_12770	COG0589	response to stress
HHJ45_12775	COG3182	Iron-regulated membrane protein
HHJ45_12780	COG0668	transmembrane transport
HHJ45_12785	COG4166	transmembrane transport
HHJ45_12790	COG0583	DNA-binding transcription factor activity
HHJ45_12795	COG1073	alpha beta
HHJ45_12810	COG2866	Carboxypeptidase
HHJ45_12815	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ45_12820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHJ45_12825	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HHJ45_12835	COG3106	COG3106 Predicted ATPase
HHJ45_12840	COG1609	Transcriptional regulator
HHJ45_12850	COG3842	ATPase activity
HHJ45_12855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ45_12860	COG1554	hydrolase, family 65, central catalytic
HHJ45_12865	COG0673	inositol 2-dehydrogenase activity
HHJ45_12870	COG1082	Xylose isomerase domain protein TIM barrel
HHJ45_12875	COG1063	alcohol dehydrogenase
HHJ45_12880	COG0395	ABC-type sugar transport system, permease component
HHJ45_12885	COG1175	transmembrane transport
HHJ45_12890	COG1653	transport
HHJ45_12895	COG0366	Alpha amylase catalytic
HHJ45_12900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ45_12910	COG1983	PspC domain protein
HHJ45_12920	COG1842	Phage shock protein A
HHJ45_12925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HHJ45_12930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHJ45_12935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HHJ45_12940	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_12945	COG1917	Cupin 2, conserved barrel domain protein
HHJ45_12945	COG1396	sequence-specific DNA binding
HHJ45_12950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HHJ45_12955	COG0174	glutamine synthetase
HHJ45_12965	COG0531	amino acid
HHJ45_12975	COG4166	transmembrane transport
HHJ45_12980	COG4168	peptide transport system, permease
HHJ45_12985	COG4171	peptide transport system, permease
HHJ45_12990	COG4172	Belongs to the ABC transporter superfamily
HHJ45_12995	COG4172	Belongs to the ABC transporter superfamily
HHJ45_13000	COG2852	Protein conserved in bacteria
HHJ45_13005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HHJ45_13010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ45_13010	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ45_13025	COG5001	Diguanylate cyclase
HHJ45_13035	COG1349	DNA-binding transcription factor activity
HHJ45_13045	COG0023	Translation Initiation Factor
HHJ45_13055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HHJ45_13060	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HHJ45_13065	COG0671	phosphoesterase, PA-phosphatase related
HHJ45_13075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHJ45_13100	COG0583	DNA-binding transcription factor activity
HHJ45_13105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHJ45_13115	COG0616	signal peptide processing
HHJ45_13120	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_13125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HHJ45_13130	COG1187	pseudouridine synthase activity
HHJ45_13135	COG0009	L-threonylcarbamoyladenylate synthase
HHJ45_13140	COG0613	PHP domain protein
HHJ45_13150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHJ45_13155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHJ45_13155	COG0512	Glutamine amidotransferase of anthranilate synthase
HHJ45_13160	COG0135	phosphoribosylanthranilate isomerase activity
HHJ45_13160	COG0134	indole-3-glycerol-phosphate synthase activity
HHJ45_13175	COG3729	General stress protein
HHJ45_13180	COG3685	Protein conserved in bacteria
HHJ45_13185	COG3685	Protein conserved in bacteria
HHJ45_13190	COG3047	cAMP biosynthetic process
HHJ45_13210	COG1607	acyl-coa hydrolase
HHJ45_13215	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HHJ45_13220	COG2350	Protein conserved in bacteria
HHJ45_13225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HHJ45_13245	COG4608	Belongs to the ABC transporter superfamily
HHJ45_13250	COG0444	Belongs to the ABC transporter superfamily
HHJ45_13255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ45_13260	COG0601	transmembrane transport
HHJ45_13265	COG4166	transmembrane transport
HHJ45_13275	COG2095	MarC family integral membrane protein
HHJ45_13280	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_13280	COG1454	alcohol dehydrogenase
HHJ45_13285	COG1435	thymidine kinase activity
HHJ45_13295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HHJ45_13300	COG0745	RESPONSE REGULATOR receiver
HHJ45_13305	COG1752	Esterase of the alpha-beta hydrolase superfamily
HHJ45_13315	COG0788	formyltetrahydrofolate deformylase activity
HHJ45_13335	COG2181	nitrate reductase activity
HHJ45_13340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HHJ45_13345	COG1140	nitrate reductase beta subunit
HHJ45_13350	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHJ45_13355	COG2223	nitrite transmembrane transporter activity
HHJ45_13360	COG3850	Histidine kinase
HHJ45_13365	COG2197	response regulator
HHJ45_13370	COG4932	domain protein
HHJ45_13375	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HHJ45_13380	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HHJ45_13385	COG4572	Cation transport regulator
HHJ45_13390	COG0387	Pfam Sodium calcium exchanger
HHJ45_13415	COG2912	Transglutaminase-like superfamily
HHJ45_13420	COG3094	Invasion gene expression up-regulator, SirB
HHJ45_13425	COG2890	protein-(glutamine-N5) methyltransferase activity
HHJ45_13450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHJ45_13455	COG0659	secondary active sulfate transmembrane transporter activity
HHJ45_13470	COG0012	GTP binding
HHJ45_13475	COG3468	outer membrane autotransporter barrel domain protein
HHJ45_13480	COG3284	Transcriptional regulator
HHJ45_13485	COG2376	Dihydroxyacetone kinase
HHJ45_13490	COG1461	Dihydroxyacetone kinase
HHJ45_13495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ45_13495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_13495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HHJ45_13515	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HHJ45_13525	COG1619	proteins homologs of microcin C7 resistance protein MccF
HHJ45_13535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHJ45_13545	COG2719	SpoVR family
HHJ45_13560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HHJ45_13565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHJ45_13570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHJ45_13585	COG0179	Fumarylacetoacetate (FAA) hydrolase
HHJ45_13610	COG2894	cell division
HHJ45_13665	COG2200	EAL domain
HHJ45_13680	COG5562	phage envelope protein
HHJ45_13695	COG0538	isocitrate dehydrogenase activity
HHJ45_13700	COG1187	pseudouridine synthase activity
HHJ45_13720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHJ45_13730	COG2205	protein histidine kinase activity
HHJ45_13735	COG2850	peptidyl-arginine hydroxylation
HHJ45_13745	COG3842	ATPase activity
HHJ45_13755	COG1177	transmembrane transport
HHJ45_13760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ45_13770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ45_13775	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ45_13780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHJ45_13790	COG4591	ABC-type transport system involved in lipoprotein release permease component
HHJ45_13795	COG1136	(ABC) transporter
HHJ45_13800	COG4591	ABC-type transport system involved in lipoprotein release permease component
HHJ45_13805	COG4763	Acyl-transferase
HHJ45_13810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHJ45_13815	COG1388	LysM domain
HHJ45_13815	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ45_13825	COG1309	transcriptional regulator
HHJ45_13830	COG3134	Outer membrane lipoprotein
HHJ45_13835	COG1252	NADH dehydrogenase
HHJ45_13855	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HHJ45_13860	COG5633	Lipoprotein
HHJ45_13865	COG0537	adenosine 5'-monophosphoramidase activity
HHJ45_13870	COG4773	Receptor
HHJ45_13875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_13875	COG1263	PTS System
HHJ45_13880	COG0084	hydrolase, TatD family'
HHJ45_13885	COG0470	DNA polymerase III
HHJ45_13895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHJ45_13900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HHJ45_13905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HHJ45_13915	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_13920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HHJ45_13940	COG1399	metal-binding, possibly nucleic acid-binding protein
HHJ45_13945	COG0424	maF-like protein
HHJ45_13950	COG0564	pseudouridine synthase activity
HHJ45_13955	COG1530	ribonuclease E activity
HHJ45_13960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHJ45_13965	COG1256	bacterial-type flagellum assembly
HHJ45_13970	COG3951	Flagellar rod assembly protein muramidase FlgJ
HHJ45_13970	COG1705	Flagellar rod assembly protein muramidase FlgJ
HHJ45_13985	COG4786	Flagellar basal body rod
HHJ45_13990	COG4787	bacterial-type flagellum-dependent cell motility
HHJ45_13995	COG1749	Flagellar hook protein flgE
HHJ45_14000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HHJ45_14005	COG1558	bacterial-type flagellum-dependent cell motility
HHJ45_14010	COG1815	bacterial-type flagellum-dependent cell motility
HHJ45_14015	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HHJ45_14020	COG2747	anti-sigma28 factor FlgM
HHJ45_14025	COG3418	PFAM FlgN family protein
HHJ45_14030	COG0728	peptidoglycan biosynthetic process
HHJ45_14035	COG0673	inositol 2-dehydrogenase activity
HHJ45_14045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ45_14055	COG2999	glutathione oxidoreductase activity
HHJ45_14090	COG3038	cytochrome b561
HHJ45_14095	COG2353	YceI-like domain
HHJ45_14105	COG1560	Kdo2-lipid A biosynthetic process
HHJ45_14120	COG5645	(Lipo)protein
HHJ45_14125	COG2943	transferase activity, transferring hexosyl groups
HHJ45_14140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ45_14145	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ45_14170	COG2197	response regulator
HHJ45_14185	COG1462	curli production assembly transport component CsgG
HHJ45_14195	COG3381	protein complex oligomerization
HHJ45_14235	COG0457	Tetratricopeptide repeat
HHJ45_14240	COG1649	PFAM Uncharacterised BCR, COG1649
HHJ45_14240	COG0726	polysaccharide deacetylase
HHJ45_14245	COG1215	transferase activity, transferring glycosyl groups
HHJ45_14250	COG3658	cytochrome
HHJ45_14255	COG1702	phosphate starvation-inducible protein PhoH
HHJ45_14265	COG2822	iron ion transport
HHJ45_14275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHJ45_14285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ45_14285	COG0506	proline dehydrogenase activity
HHJ45_14285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ45_14290	COG1309	transcriptional regulator
HHJ45_14325	COG2233	PERMEase
HHJ45_14330	COG3729	General stress protein
HHJ45_14370	COG0243	molybdopterin cofactor binding
HHJ45_14375	COG3005	denitrification pathway
HHJ45_14380	COG0745	RESPONSE REGULATOR receiver
HHJ45_14385	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_14390	COG0784	Response regulator, receiver
HHJ45_14390	COG2198	Histidine kinase
HHJ45_14390	COG2205	protein histidine kinase activity
HHJ45_14395	COG0348	domain, Protein
HHJ45_14415	COG1278	Cold shock
HHJ45_14420	COG1278	Cold shock
HHJ45_14440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ45_14445	COG1596	polysaccharide export
HHJ45_14450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHJ45_14455	COG0489	protein tyrosine kinase activity
HHJ45_14455	COG3206	protein involved in exopolysaccharide biosynthesis
HHJ45_14470	COG1294	oxidase, subunit
HHJ45_14475	COG1271	oxidase subunit
HHJ45_14480	COG1773	rubredoxin
HHJ45_14485	COG1999	signal sequence binding
HHJ45_14490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ45_14495	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HHJ45_14500	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HHJ45_14505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HHJ45_14515	COG0670	Belongs to the BI1 family
HHJ45_14520	COG2920	part of a sulfur-relay system
HHJ45_14525	COG1254	Belongs to the acylphosphatase family
HHJ45_14540	COG1832	CoA-binding protein
HHJ45_14555	COG0210	DNA helicase
HHJ45_14560	COG3304	Inner membrane component domain
HHJ45_14565	COG1289	transmembrane transporter activity
HHJ45_14570	COG3070	regulator of competence-specific genes
HHJ45_14590	COG1067	ATP-dependent peptidase activity
HHJ45_14600	COG3130	regulation of translation
HHJ45_14605	COG3009	Protein conserved in bacteria
HHJ45_14610	COG3008	intermembrane lipid transfer
HHJ45_14610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HHJ45_14615	COG2995	paraquat-inducible protein a
HHJ45_14620	COG0488	(ABC) transporter
HHJ45_14630	COG0633	Ferredoxin
HHJ45_14630	COG3217	Mosc domain protein beta barrel domain protein
HHJ45_14645	COG3121	Chaperone
HHJ45_14650	COG3539	Fimbrial protein
HHJ45_14655	COG3539	Fimbrial protein
HHJ45_14660	COG3539	Fimbrial protein
HHJ45_14665	COG3188	usher protein
HHJ45_14670	COG3121	Chaperone
HHJ45_14675	COG3539	Fimbrial protein
HHJ45_14680	COG0431	NADPH-dependent FMN reductase
HHJ45_14685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HHJ45_14695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HHJ45_14705	COG0308	aminopeptidase N
HHJ45_14720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ45_14725	COG1448	Aminotransferase
HHJ45_14735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HHJ45_14740	COG3108	Peptidase M15
HHJ45_14745	COG2989	Protein conserved in bacteria
HHJ45_14755	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HHJ45_14765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HHJ45_14770	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HHJ45_14775	COG3173	Aminoglycoside phosphotransferase
HHJ45_14790	COG3214	Protein conserved in bacteria
HHJ45_14800	COG1132	(ABC) transporter
HHJ45_14805	COG0658	competence protein
HHJ45_14805	COG2333	competence protein COMEC
HHJ45_14815	COG0539	negative regulation of cytoplasmic translation
HHJ45_14825	COG0501	Belongs to the peptidase M48B family
HHJ45_14840	COG2323	membrane
HHJ45_14845	COG1944	ATP diphosphatase activity
HHJ45_14850	COG2116	formate transmembrane transporter activity
HHJ45_14855	COG1882	Formate acetyltransferase
HHJ45_14860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ45_14865	COG2249	NAD(P)H dehydrogenase (quinone) activity
HHJ45_14870	COG0583	DNA-binding transcription factor activity
HHJ45_14875	COG0531	amino acid
HHJ45_14885	COG1335	isochorismatase
HHJ45_14890	COG3302	dmso reductase anchor subunit
HHJ45_14895	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_14900	COG0243	molybdopterin cofactor binding
HHJ45_14910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HHJ45_14925	COG1522	sequence-specific DNA binding
HHJ45_14930	COG0492	ferredoxin-NADP+ reductase activity
HHJ45_14935	COG4988	ABC transporter
HHJ45_14940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHJ45_14995	COG2003	Belongs to the UPF0758 family
HHJ45_15020	COG2020	methyltransferase activity
HHJ45_15025	COG3468	outer membrane autotransporter barrel domain protein
HHJ45_15110	COG1595	DNA-templated transcription, initiation
HHJ45_15115	COG3712	iron ion homeostasis
HHJ45_15120	COG4772	TonB-dependent receptor
HHJ45_15125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HHJ45_15130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ45_15135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ45_15140	COG1120	ATPase activity
HHJ45_15145	COG2085	NADP oxidoreductase coenzyme F420-dependent
HHJ45_15165	COG0726	polysaccharide deacetylase
HHJ45_15170	COG0297	glycogen (starch) synthase activity
HHJ45_15175	COG2990	Protein conserved in bacteria
HHJ45_15190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HHJ45_15210	COG0531	amino acid
HHJ45_15215	COG1982	Orn Lys Arg decarboxylase major
HHJ45_15220	COG0531	amino acid
HHJ45_15235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HHJ45_15245	COG0583	DNA-binding transcription factor activity
HHJ45_15275	COG0738	Major facilitator superfamily
HHJ45_15285	COG1349	DNA-binding transcription factor activity
HHJ45_15300	COG2721	sulfolactate sulfo-lyase activity
HHJ45_15305	COG2721	sulfolactate sulfo-lyase activity
HHJ45_15310	COG1349	DNA-binding transcription factor activity
HHJ45_15320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_15320	COG1263	PTS System
HHJ45_15325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HHJ45_15335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHJ45_15360	COG4983	Phage plasmid primase, P4 family domain protein
HHJ45_15390	COG0582	viral genome integration into host DNA
HHJ45_15395	COG0542	response to heat
HHJ45_15405	COG1278	Cold shock
HHJ45_15410	COG1136	(ABC) transporter
HHJ45_15410	COG0577	efflux transmembrane transporter activity
HHJ45_15415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_15420	COG2990	Protein conserved in bacteria
HHJ45_15425	COG3593	DNA synthesis involved in DNA repair
HHJ45_15435	COG2431	L-lysine efflux transmembrane transporter activity
HHJ45_15445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ45_15450	COG0028	Belongs to the TPP enzyme family
HHJ45_15455	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HHJ45_15465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ45_15470	COG3023	N-Acetylmuramoyl-L-alanine amidase
HHJ45_15485	COG1126	abc transporter atp-binding protein
HHJ45_15490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_15495	COG4215	(ABC) transporter
HHJ45_15500	COG4160	amino acid transport
HHJ45_15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_15520	COG1177	transmembrane transport
HHJ45_15525	COG1176	ABC-type spermidine putrescine transport system, permease component I
HHJ45_15530	COG3842	ATPase activity
HHJ45_15535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ45_15570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ45_15585	COG3226	Transcriptional regulator
HHJ45_15590	COG0738	Major facilitator superfamily
HHJ45_15595	COG0561	phosphatase activity
HHJ45_15605	COG2814	Major facilitator Superfamily
HHJ45_15610	COG0671	phosphoesterase, PA-phosphatase related
HHJ45_15615	COG1349	DNA-binding transcription factor activity
HHJ45_15620	COG1686	Belongs to the peptidase S11 family
HHJ45_15625	COG0625	glutathione transferase activity
HHJ45_15630	COG2133	pyrroloquinoline quinone binding
HHJ45_15645	COG2199	diguanylate cyclase activity
HHJ45_15675	COG1446	asparaginase
HHJ45_15680	COG0303	'Molybdopterin
HHJ45_15685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HHJ45_15690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ45_15695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ45_15700	COG1882	Formate acetyltransferase
HHJ45_15705	COG0561	phosphatase activity
HHJ45_15720	COG0488	(ABC) transporter
HHJ45_15725	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ45_15730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHJ45_15735	COG1321	iron dependent repressor
HHJ45_15745	COG2194	sulfuric ester hydrolase activity
HHJ45_15750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HHJ45_15760	COG5006	permease, DMT superfamily
HHJ45_15770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_15775	COG0765	amino acid transport
HHJ45_15780	COG1126	abc transporter atp-binding protein
HHJ45_15785	COG0668	transmembrane transport
HHJ45_15800	COG4774	siderophore transport
HHJ45_15810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HHJ45_15825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ45_15830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHJ45_15835	COG1199	ATP-dependent helicase activity
HHJ45_15840	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HHJ45_15845	COG0513	Belongs to the DEAD box helicase family
HHJ45_15850	COG1309	transcriptional regulator
HHJ45_15860	COG1131	(ABC) transporter
HHJ45_15865	COG0842	Transport permease protein
HHJ45_15870	COG0842	Transport permease protein
HHJ45_15880	COG3568	Endonuclease Exonuclease Phosphatase
HHJ45_15885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ45_15890	COG0392	lysyltransferase activity
HHJ45_15895	COG0670	Belongs to the BI1 family
HHJ45_15905	COG0670	Belongs to the BI1 family
HHJ45_15910	COG0314	molybdopterin synthase activity
HHJ45_15915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHJ45_15925	COG0521	Mo-molybdopterin cofactor biosynthetic process
HHJ45_15935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HHJ45_15945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHJ45_15950	COG2226	methyltransferase
HHJ45_15965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HHJ45_15970	COG1881	PFAM PEBP family protein
HHJ45_15975	COG4677	pectinesterase activity
HHJ45_15980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHJ45_15985	COG0471	metal ion transport
HHJ45_15990	COG2828	Protein conserved in bacteria
HHJ45_15995	COG0583	DNA-binding transcription factor activity
HHJ45_16005	COG0561	phosphatase activity
HHJ45_16015	COG4149	molybdate abc transporter
HHJ45_16020	COG0725	ABC transporter, periplasmic molybdate-binding protein
HHJ45_16030	COG2005	Transcriptional regulator
HHJ45_16030	COG3585	molybdate ion transport
HHJ45_16035	COG1119	ATPase activity
HHJ45_16040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHJ45_16045	COG1085	galactose-1-phosphate uridylyltransferase
HHJ45_16055	COG2017	converts alpha-aldose to the beta-anomer
HHJ45_16065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ45_16075	COG1230	cation diffusion facilitator family transporter
HHJ45_16080	COG3201	nicotinamide mononucleotide transporter
HHJ45_16130	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HHJ45_16135	COG2885	chlorophyll binding
HHJ45_16145	COG3064	Membrane
HHJ45_16150	COG0848	biopolymer transport protein
HHJ45_16155	COG0811	peptide transport
HHJ45_16160	COG0824	Thioesterase
HHJ45_16165	COG3790	cyd operon protein YbgE
HHJ45_16170	COG4890	Cyd operon protein YbgT
HHJ45_16175	COG1294	oxidase, subunit
HHJ45_16180	COG1271	oxidase subunit
HHJ45_16190	COG0383	alpha-mannosidase activity
HHJ45_16195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_16195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_16195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_16200	COG2188	Transcriptional regulator
HHJ45_16205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ45_16215	COG0508	dehydrogenase complex catalyzes the overall conversion of
HHJ45_16220	COG0567	Dehydrogenase, E1 component
HHJ45_16225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HHJ45_16230	COG1053	succinate dehydrogenase
HHJ45_16235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HHJ45_16240	COG2009	succinate dehydrogenase
HHJ45_16250	COG0372	Belongs to the citrate synthase family
HHJ45_16260	COG3188	usher protein
HHJ45_16265	COG3121	Chaperone
HHJ45_16270	COG3539	Fimbrial protein
HHJ45_16275	COG3180	Ammonia monooxygenase
HHJ45_16290	COG1984	allophanate hydrolase subunit 2
HHJ45_16295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HHJ45_16300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHJ45_16310	COG0415	Belongs to the DNA photolyase family
HHJ45_16315	COG3272	Protein of unknown function (DUF1722)
HHJ45_16335	COG3209	COG3209 Rhs family protein
HHJ45_16385	COG2205	protein histidine kinase activity
HHJ45_16390	COG0745	RESPONSE REGULATOR receiver
HHJ45_16405	COG1982	Orn Lys Arg decarboxylase major
HHJ45_16410	COG0531	amino acid
HHJ45_16415	COG0033	Phosphoglucomutase
HHJ45_16420	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HHJ45_16425	COG0596	Alpha beta hydrolase
HHJ45_16435	COG0716	FMN binding
HHJ45_16445	COG0735	belongs to the Fur family
HHJ45_16465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_16465	COG1263	PTS System
HHJ45_16465	COG2190	(PTS) system
HHJ45_16475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ45_16480	COG1846	Transcriptional regulator
HHJ45_16480	COG1940	carbohydrate kinase activity
HHJ45_16485	COG0647	UMP catabolic process
HHJ45_16490	COG0367	asparagine synthase
HHJ45_16530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ45_16540	COG1702	phosphate starvation-inducible protein PhoH
HHJ45_16550	COG4535	Mg2 and Co2 transporter CorC
HHJ45_16555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HHJ45_16565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ45_16570	COG0765	amino acid transport
HHJ45_16575	COG0765	amino acid transport
HHJ45_16580	COG1126	abc transporter atp-binding protein
HHJ45_16590	COG0443	Heat shock 70 kDa protein
HHJ45_16595	COG2214	Heat shock protein DnaJ domain protein
HHJ45_16610	COG2214	Heat shock protein DnaJ domain protein
HHJ45_16620	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HHJ45_16625	COG2888	peptidyl-tyrosine sulfation
HHJ45_16640	COG1466	dna polymerase III delta subunit
HHJ45_16650	COG0406	alpha-ribazole phosphatase activity
HHJ45_16655	COG0799	negative regulation of ribosome biogenesis
HHJ45_16665	COG0768	penicillin binding
HHJ45_16670	COG0772	Belongs to the SEDS family
HHJ45_16675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHJ45_16680	COG1686	Belongs to the peptidase S11 family
HHJ45_16695	COG0583	DNA-binding transcription factor activity
HHJ45_16705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHJ45_16710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ45_16730	COG3069	C4-dicarboxylate transmembrane transporter activity
HHJ45_16735	COG4565	transcriptional regulatory protein
HHJ45_16740	COG3290	protein histidine kinase activity
HHJ45_16745	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HHJ45_16755	COG2301	Belongs to the HpcH HpaI aldolase family
HHJ45_16760	COG3051	citrate lyase alpha subunit
HHJ45_16775	COG0471	metal ion transport
HHJ45_16780	COG3719	Belongs to the RNase T2 family
HHJ45_16785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ45_16790	COG1063	alcohol dehydrogenase
HHJ45_16795	COG0589	response to stress
HHJ45_16800	COG3634	alkyl hydroperoxide reductase activity
HHJ45_16805	COG0450	alkyl hydroperoxide reductase
HHJ45_16810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HHJ45_16815	COG0583	DNA-binding transcription factor activity
HHJ45_16820	COG3969	phosphoadenosine phosphosulfate
HHJ45_16825	COG1475	DNA binding
HHJ45_16830	COG0436	Aminotransferase
HHJ45_16835	COG0371	Dehydrogenase
HHJ45_16840	COG2879	small protein
HHJ45_16845	COG1966	Carbon starvation protein
HHJ45_16850	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ45_16855	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_16860	COG3433	isochorismatase activity
HHJ45_16860	COG1535	isochorismatase
HHJ45_16865	COG1021	2,3-dihydroxybenzoate-AMP ligase
HHJ45_16870	COG1169	isochorismate synthase
HHJ45_16875	COG4592	Periplasmic binding protein
HHJ45_16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ45_16890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ45_16895	COG1120	ATPase activity
HHJ45_16900	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HHJ45_16905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HHJ45_16905	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HHJ45_16910	COG3251	PFAM MbtH domain protein
HHJ45_16915	COG2382	esterase
HHJ45_16920	COG4771	TonB-dependent receptor
HHJ45_16925	COG2977	Belongs to the P-Pant transferase superfamily
HHJ45_16950	COG2315	Protein conserved in bacteria
HHJ45_16955	COG0778	Nitroreductase
HHJ45_16960	COG0668	transmembrane transport
HHJ45_16965	COG1113	amino acid transport
HHJ45_16970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ45_16975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_16980	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_16985	COG1538	Outer membrane efflux protein
HHJ45_16990	COG0745	RESPONSE REGULATOR receiver
HHJ45_16995	COG5002	protein histidine kinase activity
HHJ45_17005	COG3501	Rhs element vgr protein
HHJ45_17040	COG1215	transferase activity, transferring glycosyl groups
HHJ45_17045	COG4783	chaperone-mediated protein folding
HHJ45_17055	COG2207	Transcriptional regulator
HHJ45_17060	COG4571	Outer membrane protease
HHJ45_17090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HHJ45_17095	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ45_17100	COG5301	cellulose 1,4-beta-cellobiosidase activity
HHJ45_17135	COG1196	nuclear chromosome segregation
HHJ45_17185	COG1030	water channel activity
HHJ45_17205	COG4220	transposase activity
HHJ45_17225	COG3772	lysozyme
HHJ45_17370	COG0582	viral genome integration into host DNA
HHJ45_17380	COG2197	response regulator
HHJ45_17385	COG3539	Fimbrial protein
HHJ45_17390	COG3539	Fimbrial protein
HHJ45_17395	COG3188	usher protein
HHJ45_17400	COG3121	Chaperone
HHJ45_17405	COG3539	Fimbrial protein
HHJ45_17415	COG2501	S4 domain
HHJ45_17420	COG1988	membrane-bound metal-dependent
HHJ45_17430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHJ45_17440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHJ45_17445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHJ45_17450	COG0549	Belongs to the carbamate kinase family
HHJ45_17460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ45_17465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ45_17470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ45_17475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HHJ45_17480	COG3257	ureidoglycine aminohydrolase activity
HHJ45_17485	COG1929	Belongs to the glycerate kinase type-1 family
HHJ45_17490	COG2233	PERMEase
HHJ45_17500	COG1953	Uracil, thiamine, allantoin
HHJ45_17505	COG2084	Dehydrogenase
HHJ45_17510	COG3622	Belongs to the hyi family
HHJ45_17515	COG3960	tartronate-semialdehyde synthase activity
HHJ45_17520	COG1414	Transcriptional regulator
HHJ45_17530	COG0583	DNA-binding transcription factor activity
HHJ45_17540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HHJ45_17545	COG4181	ATPase activity
HHJ45_17550	COG2755	lipolytic protein G-D-S-L family
HHJ45_17555	COG0300	oxidoreductase activity
HHJ45_17560	COG3118	belongs to the thioredoxin family
HHJ45_17565	COG0390	transport system, permease component
HHJ45_17570	COG4619	ABC transporter
HHJ45_17575	COG0330	HflC and HflK could
HHJ45_17580	COG1585	Membrane protein implicated in regulation of membrane protease activity
HHJ45_17585	COG0789	Transcriptional regulator
HHJ45_17590	COG0531	amino acid
HHJ45_17595	COG2066	Belongs to the glutaminase family
HHJ45_17600	COG2217	Heavy metal translocating P-type atpase
HHJ45_17605	COG3093	addiction module antidote protein HigA
HHJ45_17610	COG3735	TraB family
HHJ45_17615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHJ45_17620	COG0737	Belongs to the 5'-nucleotidase family
HHJ45_17625	COG2223	nitrite transmembrane transporter activity
HHJ45_17630	COG4651	solute:proton antiporter activity
HHJ45_17630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HHJ45_17635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_17670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHJ45_17680	COG2832	Protein of unknown function (DUF454)
HHJ45_17685	COG3923	Primosomal replication protein n
HHJ45_17695	COG3264	Mechanosensitive ion channel
HHJ45_17695	COG1196	nuclear chromosome segregation
HHJ45_17700	COG1309	transcriptional regulator
HHJ45_17705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_17710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ45_17725	COG0110	maltose O-acetyltransferase activity
HHJ45_17735	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HHJ45_17740	COG5507	3-demethylubiquinone-9 3-methyltransferase
HHJ45_17750	COG3695	enzyme binding
HHJ45_17755	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HHJ45_17760	COG1946	Acyl-CoA thioesterase
HHJ45_17765	COG0004	ammonium transporteR
HHJ45_17770	COG0347	Belongs to the P(II) protein family
HHJ45_17775	COG1132	(ABC) transporter
HHJ45_17780	COG1132	(ABC) transporter
HHJ45_17785	COG1522	sequence-specific DNA binding
HHJ45_17795	COG4533	DNA binding
HHJ45_17805	COG0824	Thioesterase
HHJ45_17810	COG1555	photosystem II stabilization
HHJ45_17815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ45_17820	COG0776	regulation of translation
HHJ45_17825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHJ45_17845	COG0271	Belongs to the BolA IbaG family
HHJ45_17850	COG3056	Lipoprotein
HHJ45_17855	COG2223	nitrite transmembrane transporter activity
HHJ45_17860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HHJ45_17865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHJ45_17870	COG1845	cytochrome c oxidase, subunit III
HHJ45_17875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HHJ45_17900	COG2814	Major facilitator Superfamily
HHJ45_17910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHJ45_17915	COG0693	protein deglycase activity
HHJ45_17930	COG0142	geranyltranstransferase activity
HHJ45_17940	COG0667	Aldo Keto reductase
HHJ45_17945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HHJ45_17950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHJ45_17965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHJ45_17965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHJ45_17975	COG4238	major outer membrane lipoprotein
HHJ45_17980	COG3248	Nucleoside-binding outer membrane protein
HHJ45_17985	COG1403	HNH endonuclease
HHJ45_17990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHJ45_17995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHJ45_18000	COG1862	Preprotein translocase
HHJ45_18025	COG1113	amino acid transport
HHJ45_18030	COG1114	Component of the transport system for branched-chain amino acids
HHJ45_18035	COG5002	protein histidine kinase activity
HHJ45_18040	COG0745	RESPONSE REGULATOR receiver
HHJ45_18045	COG0420	3'-5' exonuclease activity
HHJ45_18050	COG0419	ATPase involved in DNA repair
HHJ45_18055	COG2814	Major facilitator Superfamily
HHJ45_18060	COG1940	carbohydrate kinase activity
HHJ45_18080	COG4126	flavin adenine dinucleotide binding
HHJ45_18100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHJ45_18105	COG3706	GGDEF domain
HHJ45_18115	COG1785	Belongs to the alkaline phosphatase family
HHJ45_18130	COG1181	Belongs to the D-alanine--D-alanine ligase family
HHJ45_18150	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HHJ45_18155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HHJ45_18160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ45_18165	COG3468	outer membrane autotransporter barrel domain protein
HHJ45_18170	COG0113	porphobilinogen synthase activity
HHJ45_18175	COG2175	clavaminate synthase activity
HHJ45_18180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HHJ45_18190	COG4521	taurine ABC transporter
HHJ45_18195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HHJ45_18200	COG1215	transferase activity, transferring glycosyl groups
HHJ45_18230	COG3122	Protein conserved in bacteria
HHJ45_18235	COG2814	Major facilitator Superfamily
HHJ45_18270	COG1414	Transcriptional regulator
HHJ45_18275	COG1609	Transcriptional regulator
HHJ45_18280	COG3250	beta-galactosidase activity
HHJ45_18285	COG2223	nitrite transmembrane transporter activity
HHJ45_18290	COG0110	maltose O-acetyltransferase activity
HHJ45_18300	COG2807	transmembrane transport
HHJ45_18310	COG0288	reversible hydration of carbon dioxide
HHJ45_18315	COG0583	DNA-binding transcription factor activity
HHJ45_18320	COG0402	S-adenosylhomocysteine deaminase activity
HHJ45_18325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HHJ45_18330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HHJ45_18335	COG2079	MmgE PrpD family protein
HHJ45_18340	COG0372	Belongs to the citrate synthase family
HHJ45_18345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHJ45_18350	COG3829	transcription factor binding
HHJ45_18360	COG1280	lysine exporter protein (LysE YggA)
HHJ45_18375	COG1064	alcohol dehydrogenase
HHJ45_18385	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_18390	COG1129	ABC transporter
HHJ45_18395	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_18405	COG0402	S-adenosylhomocysteine deaminase activity
HHJ45_18410	COG0549	Belongs to the carbamate kinase family
HHJ45_18415	COG1304	FMN binding
HHJ45_18420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ45_18430	COG0666	response to abiotic stimulus
HHJ45_18440	COG0583	DNA-binding transcription factor activity
HHJ45_18445	COG2771	luxR family
HHJ45_18445	COG2200	EAL domain
HHJ45_18455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HHJ45_18495	COG2200	EAL domain
HHJ45_18495	COG2771	luxR family
HHJ45_18515	COG3468	outer membrane autotransporter barrel domain protein
HHJ45_18525	COG1556	Lactate utilization protein
HHJ45_18530	COG1139	Iron-sulfur cluster binding protein
HHJ45_18535	COG0247	lactate metabolic process
HHJ45_18540	COG2207	Transcriptional regulator
HHJ45_18545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ45_18555	COG3059	membrane
HHJ45_18565	COG3708	Transcriptional regulator
HHJ45_18565	COG2207	Transcriptional regulator
HHJ45_18570	COG1388	LysM domain
HHJ45_18605	COG3188	usher protein
HHJ45_18615	COG3121	Chaperone
HHJ45_18620	COG0727	PFAM Uncharacterised protein family (UPF0153)
HHJ45_18625	COG3477	response to acidic pH
HHJ45_18630	COG2080	2 iron, 2 sulfur cluster binding
HHJ45_18635	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HHJ45_18645	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHJ45_18650	COG0583	DNA-binding transcription factor activity
HHJ45_18670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ45_18690	COG2195	Cleaves the N-terminal amino acid of tripeptides
HHJ45_18695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHJ45_18700	COG1690	Belongs to the RtcB family
HHJ45_18705	COG0454	-acetyltransferase
HHJ45_18735	COG0791	NLP P60 protein
HHJ45_18740	COG3077	Addiction module antitoxin, RelB DinJ family
HHJ45_18745	COG3041	Addiction module toxin RelE StbE family
HHJ45_18750	COG3034	peptidoglycan biosynthetic process
HHJ45_18755	COG0121	glutamine amidotransferase
HHJ45_18765	COG1960	acyl-CoA dehydrogenase activity
HHJ45_18775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ45_18820	COG3209	COG3209 Rhs family protein
HHJ45_18825	COG3501	Rhs element vgr protein
HHJ45_18910	COG3157	Type VI secretion system effector, Hcp
HHJ45_18915	COG4104	PAAR repeat-containing protein
HHJ45_18935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ45_18945	COG2226	methyltransferase
HHJ45_18955	COG0741	lytic transglycosylase activity
HHJ45_18955	COG1388	LysM domain
HHJ45_18960	COG2226	methyltransferase
HHJ45_18970	COG0583	DNA-binding transcription factor activity
HHJ45_18975	COG0656	L-ascorbic acid biosynthetic process
HHJ45_19010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HHJ45_19015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHJ45_19020	COG2011	ABC-type metal ion transport system permease component
HHJ45_19025	COG1464	Belongs to the NlpA lipoprotein family
HHJ45_19035	COG1720	tRNA m6t6A37 methyltransferase activity
HHJ45_19055	COG3015	lipoprotein NlpE involved in copper resistance
HHJ45_19060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHJ45_19065	COG4681	YaeQ
HHJ45_19075	COG4568	rho-dependent transcription termination
HHJ45_19085	COG0346	lactoylglutathione lyase activity
HHJ45_19100	COG0587	DNA-directed DNA polymerase activity
HHJ45_19125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HHJ45_19130	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HHJ45_19140	COG0750	zinc metalloprotease
HHJ45_19145	COG0575	Belongs to the CDS family
HHJ45_19150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHJ45_19155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HHJ45_19180	COG0024	Methionine aminopeptidase
HHJ45_19200	COG3835	regulator
HHJ45_19205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ45_19220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HHJ45_19225	COG2860	membrane
HHJ45_19250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ45_19255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HHJ45_19260	COG1120	ATPase activity
HHJ45_19265	COG4774	siderophore transport
HHJ45_19270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HHJ45_19275	COG1643	Atp-dependent helicase
HHJ45_19280	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHJ45_19290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HHJ45_19300	COG0617	tRNA 3'-terminal CCA addition
HHJ45_19305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHJ45_19310	COG3539	Fimbrial protein
HHJ45_19315	COG3121	Chaperone
HHJ45_19320	COG3188	usher protein
HHJ45_19325	COG3539	Fimbrial protein
HHJ45_19330	COG3539	Fimbrial protein
HHJ45_19335	COG3539	Fimbrial protein
HHJ45_19340	COG3539	Fimbrial protein
HHJ45_19355	COG5464	transposase or invertase
HHJ45_19365	COG0726	polysaccharide deacetylase
HHJ45_19370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_19375	COG0842	Transport permease protein
HHJ45_19380	COG1131	(ABC) transporter
HHJ45_19385	COG0288	reversible hydration of carbon dioxide
HHJ45_19390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHJ45_19395	COG4993	Dehydrogenase
HHJ45_19405	COG2132	Multicopper oxidase
HHJ45_19430	COG1049	propionate catabolic process, 2-methylcitrate cycle
HHJ45_19435	COG3064	Membrane
HHJ45_19440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ45_19445	COG0508	dehydrogenase complex catalyzes the overall conversion of
HHJ45_19450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HHJ45_19455	COG2186	Transcriptional regulator
HHJ45_19460	COG1113	amino acid transport
HHJ45_19465	COG3725	Membrane protein required for beta-lactamase induction
HHJ45_19470	COG3023	N-Acetylmuramoyl-L-alanine amidase
HHJ45_19475	COG0157	Belongs to the NadC ModD family
HHJ45_19480	COG4969	Belongs to the N-Me-Phe pilin family
HHJ45_19485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHJ45_19490	COG1459	type II secretion system
HHJ45_19500	COG0237	dephospho-CoA kinase activity
HHJ45_19515	COG0494	nUDIX hydrolase
HHJ45_19535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHJ45_19540	COG0849	cell division
HHJ45_19545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HHJ45_19550	COG1181	Belongs to the D-alanine--D-alanine ligase family
HHJ45_19565	COG0772	Belongs to the SEDS family
HHJ45_19580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HHJ45_19585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHJ45_19590	COG0768	penicillin binding
HHJ45_19595	COG3116	cell division
HHJ45_19610	COG1609	Transcriptional regulator
HHJ45_19620	COG0440	acetolactate synthase activity
HHJ45_19625	COG0028	Belongs to the TPP enzyme family
HHJ45_19630	COG0583	DNA-binding transcription factor activity
HHJ45_19645	COG0473	3-isopropylmalate dehydrogenase activity
HHJ45_19660	COG2814	Major facilitator Superfamily
HHJ45_19675	COG4143	(ABC) transporter
HHJ45_19680	COG1178	ABC-type Fe3 transport system permease component
HHJ45_19690	COG0586	Pfam SNARE associated Golgi protein
HHJ45_19695	COG4977	sequence-specific DNA binding
HHJ45_19710	COG0235	Class ii aldolase
HHJ45_19715	COG0417	DNA replication proofreading
HHJ45_19725	COG0564	pseudouridine synthase activity
HHJ45_19735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HHJ45_19740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HHJ45_19745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ45_19770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHJ45_19785	COG2271	Major facilitator Superfamily
HHJ45_19790	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HHJ45_19795	COG0644	oxidoreductase
HHJ45_19855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HHJ45_19860	COG0505	Belongs to the CarA family
HHJ45_19880	COG1047	Peptidyl-prolyl cis-trans
HHJ45_19895	COG0196	riboflavin kinase activity
HHJ45_19925	COG0583	DNA-binding transcription factor activity
HHJ45_19955	COG4735	regulation of single-species biofilm formation
HHJ45_19960	COG1584	GPR1 FUN34 yaaH family protein
HHJ45_19965	COG0521	Mo-molybdopterin cofactor biosynthetic process
HHJ45_19970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ45_19975	COG1115	amino acid carrier protein
HHJ45_19995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHJ45_20005	COG0460	homoserine dehydrogenase
HHJ45_20005	COG0527	aspartate kinase activity
HHJ45_20015	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HHJ45_20025	COG0745	RESPONSE REGULATOR receiver
HHJ45_20030	COG4452	Inner membrane protein CreD
HHJ45_20035	COG2205	protein histidine kinase activity
HHJ45_20040	COG0745	RESPONSE REGULATOR receiver
HHJ45_20045	COG3045	CreA protein
HHJ45_20050	COG3708	Transcriptional regulator
HHJ45_20050	COG2207	Transcriptional regulator
HHJ45_20070	COG0741	lytic transglycosylase activity
HHJ45_20075	COG0488	(ABC) transporter
HHJ45_20080	COG3172	ATPase kinase involved in NAD metabolism
HHJ45_20080	COG1056	cytidyltransferase-related domain
HHJ45_20085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHJ45_20090	COG0560	Phosphoserine phosphatase
HHJ45_20095	COG3726	membrane protein affecting hemolysin expression
HHJ45_20130	COG1328	CTP reductase activity
HHJ45_20135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ45_20140	COG0084	hydrolase, TatD family'
HHJ45_20145	COG4667	esterase of the alpha-beta hydrolase superfamily
HHJ45_20155	COG2823	Periplasmic or secreted lipoprotein
HHJ45_20165	COG1011	Hydrolase
HHJ45_20170	COG0456	acetyltransferase
HHJ45_20175	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HHJ45_20205	COG4114	ferric iron reductase
HHJ45_20210	COG2197	response regulator
HHJ45_20215	COG2197	response regulator
HHJ45_20220	COG2966	Psort location CytoplasmicMembrane, score
HHJ45_20235	COG1484	DNA-dependent DNA replication
HHJ45_20250	COG1063	alcohol dehydrogenase
HHJ45_20255	COG1802	Transcriptional regulator
HHJ45_20260	COG2271	Major facilitator Superfamily
HHJ45_20265	COG0840	transmembrane signaling receptor activity
HHJ45_20270	COG1846	Transcriptional regulator
HHJ45_20275	COG0179	Fumarylacetoacetate (FAA) hydrolase
HHJ45_20280	COG1012	belongs to the aldehyde dehydrogenase family
HHJ45_20285	COG3384	dioxygenase
HHJ45_20295	COG3971	2-oxopent-4-enoate hydratase activity
HHJ45_20315	COG2368	4-hydroxyphenylacetate
HHJ45_20320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHJ45_20325	COG1966	Carbon starvation protein
HHJ45_20330	COG2879	small protein
HHJ45_20335	COG0523	cobalamin synthesis protein
HHJ45_20345	COG5457	Domain of unknown function (DUF1127)
HHJ45_20350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HHJ45_20360	COG2814	Major facilitator Superfamily
HHJ45_20365	COG2733	membrane
HHJ45_20370	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HHJ45_20375	COG1924	4 iron, 4 sulfur cluster binding
HHJ45_20390	COG0477	Major facilitator Superfamily
HHJ45_20400	COG3366	ferrous iron transmembrane transporter activity
HHJ45_20405	COG0700	Nucleoside recognition
HHJ45_20410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ45_20415	COG0583	DNA-binding transcription factor activity
HHJ45_20435	COG2186	Transcriptional regulator
HHJ45_20440	COG0246	Mannitol dehydrogenase
HHJ45_20450	COG2610	gluconate transmembrane transporter activity
HHJ45_20455	COG3539	Fimbrial protein
HHJ45_20460	COG3539	Fimbrial protein
HHJ45_20465	COG3539	Fimbrial protein
HHJ45_20470	COG3188	usher protein
HHJ45_20475	COG3121	Chaperone
HHJ45_20480	COG3539	Fimbrial protein
HHJ45_20490	COG4974	Belongs to the 'phage' integrase family
HHJ45_20495	COG0582	viral genome integration into host DNA
HHJ45_20500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HHJ45_20605	COG1064	alcohol dehydrogenase
HHJ45_20610	COG0433	COG0433 Predicted ATPase
HHJ45_20615	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ45_20620	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ45_20630	COG2927	DNA polymerase III (CHI subunit)
HHJ45_20635	COG0525	valine-tRNA ligase activity
HHJ45_20645	COG0456	acetyltransferase
HHJ45_20650	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HHJ45_20670	COG2731	YhcH YjgK YiaL family protein
HHJ45_20675	COG1309	transcriptional regulator
HHJ45_20680	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ45_20685	COG0251	oxidation-reduction process
HHJ45_20705	COG0251	oxidation-reduction process
HHJ45_20715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HHJ45_20725	COG1609	Transcriptional regulator
HHJ45_20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_20730	COG1263	PTS System
HHJ45_20735	COG0366	Alpha amylase catalytic
HHJ45_20740	COG1328	CTP reductase activity
HHJ45_20745	COG0602	queuosine metabolic process
HHJ45_20750	COG3783	Cytochrome b(562)
HHJ45_20755	COG0312	modulator of DNA gyrase
HHJ45_20765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HHJ45_20775	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_20780	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_20785	COG1129	ABC transporter
HHJ45_20790	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_20795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HHJ45_20800	COG2337	Toxic component of a toxin-antitoxin (TA) module
HHJ45_20805	COG2336	PFAM SpoVT AbrB
HHJ45_20810	COG2105	PFAM AIG2 family protein
HHJ45_20815	COG2911	Protein conserved in bacteria
HHJ45_20820	COG0729	surface antigen
HHJ45_20830	COG1253	flavin adenine dinucleotide binding
HHJ45_20840	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HHJ45_20845	COG1218	3'(2'),5'-bisphosphate nucleotidase
HHJ45_20850	COG0737	Belongs to the 5'-nucleotidase family
HHJ45_20855	COG1733	regulation of RNA biosynthetic process
HHJ45_20860	COG0702	epimerase
HHJ45_20865	COG0697	spore germination
HHJ45_20875	COG1113	amino acid transport
HHJ45_20880	COG0545	Peptidyl-prolyl cis-trans isomerase
HHJ45_20885	COG3061	Opacity-associated protein A
HHJ45_20890	COG1309	transcriptional regulator
HHJ45_20905	COG1024	Enoyl-CoA hydratase
HHJ45_20910	COG4670	ketone body catabolic process
HHJ45_20915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHJ45_20920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HHJ45_20930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HHJ45_20940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHJ45_20975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_20980	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ45_20985	COG3037	sugar-specific permease SgaT UlaA
HHJ45_21000	COG1073	alpha beta
HHJ45_21005	COG3650	response to hydrogen peroxide
HHJ45_21015	COG1960	acyl-CoA dehydrogenase activity
HHJ45_21020	COG0754	glutathionylspermidine amidase activity
HHJ45_21025	COG5463	Belongs to the UPF0441 family
HHJ45_21030	COG3766	membrane
HHJ45_21040	COG1842	Phage shock protein A
HHJ45_21045	COG3789	protein conserved in bacteria
HHJ45_21050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ45_21055	COG0557	exoribonuclease II activity
HHJ45_21070	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HHJ45_21075	COG0330	HflC and HflK could
HHJ45_21080	COG0330	HflC and HflK could
HHJ45_21085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHJ45_21105	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ45_21110	COG0802	atpase or kinase
HHJ45_21115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHJ45_21115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HHJ45_21120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHJ45_21160	COG3264	Mechanosensitive ion channel
HHJ45_21160	COG1511	domain protein
HHJ45_21165	COG0531	amino acid
HHJ45_21175	COG1053	succinate dehydrogenase
HHJ45_21180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HHJ45_21195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HHJ45_21200	COG3040	lipid binding
HHJ45_21205	COG2076	Multidrug Resistance protein
HHJ45_21210	COG5510	response to toxic substance
HHJ45_21215	COG5510	response to toxic substance
HHJ45_21225	COG1509	lysine 2,3-aminomutase activity
HHJ45_21250	COG0531	amino acid
HHJ45_21255	COG3030	protein affecting phage T7 exclusion by the F plasmid
HHJ45_21260	COG1027	Aspartate ammonia-lyase
HHJ45_21265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HHJ45_21280	COG1309	transcriptional regulator
HHJ45_21420	COG3344	reverse transcriptase
HHJ45_21520	COG3436	PFAM IS66 Orf2 family protein
HHJ45_21525	COG4372	Transposase
HHJ45_21560	COG3596	GTP binding
HHJ45_21565	COG2378	regulation of single-species biofilm formation
HHJ45_21590	COG2003	Belongs to the UPF0758 family
HHJ45_21605	COG3344	reverse transcriptase
HHJ45_21635	COG3710	Transcriptional regulator
HHJ45_21640	COG0531	amino acid
HHJ45_21645	COG1982	Orn Lys Arg decarboxylase major
HHJ45_21650	COG3104	oligopeptide transport
HHJ45_21655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HHJ45_21670	COG2388	GCN5-related N-acetyl-transferase
HHJ45_21675	COG3592	Divergent 4Fe-4S mono-cluster
HHJ45_21680	COG3290	protein histidine kinase activity
HHJ45_21685	COG4565	transcriptional regulatory protein
HHJ45_21690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HHJ45_21695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_21695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ45_21700	COG3647	Membrane
HHJ45_21705	COG2211	Major facilitator Superfamily
HHJ45_21710	COG1486	melibiose metabolic process
HHJ45_21715	COG2169	Transcriptional regulator
HHJ45_21720	COG1982	Orn Lys Arg decarboxylase major
HHJ45_21725	COG2207	Transcriptional regulator
HHJ45_21730	COG0531	amino acid
HHJ45_21735	COG2194	sulfuric ester hydrolase activity
HHJ45_21740	COG0745	RESPONSE REGULATOR receiver
HHJ45_21745	COG0642	Histidine kinase
HHJ45_21755	COG0477	Major facilitator Superfamily
HHJ45_21770	COG2824	Alkylphosphonate utilization operon protein PhnA
HHJ45_21775	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HHJ45_21785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HHJ45_21790	COG3639	organic phosphonate transmembrane transporter activity
HHJ45_21795	COG2188	Transcriptional regulator
HHJ45_21800	COG3624	Phosphonate C-P lyase system protein PhnG
HHJ45_21805	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HHJ45_21810	COG3626	phosphonate metabolism
HHJ45_21815	COG3627	carbon phosphorus lyase activity
HHJ45_21820	COG4107	phosphonate C-P lyase system protein PhnK
HHJ45_21825	COG4778	phosphonate C-P lyase system protein PhnL
HHJ45_21830	COG3454	Phosphonate metabolism
HHJ45_21835	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HHJ45_21840	COG0456	acetyltransferase
HHJ45_21845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HHJ45_21855	COG0698	ribose 5-phosphate isomerase
HHJ45_21860	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HHJ45_21870	COG1566	PFAM secretion protein HlyD family protein
HHJ45_21875	COG1289	transmembrane transporter activity
HHJ45_21890	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HHJ45_21895	COG1301	dicarboxylic acid transport
HHJ45_21900	COG4235	cytochrome complex assembly
HHJ45_21905	COG3088	subunit of a heme lyase
HHJ45_21910	COG1138	Cytochrome C-type biogenesis protein
HHJ45_21915	COG3301	Polysulphide reductase, NrfD
HHJ45_21920	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_21925	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HHJ45_21935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HHJ45_21940	COG3162	membrane
HHJ45_21955	COG0025	NhaP-type Na H and K H
HHJ45_21960	COG2252	PERMEase
HHJ45_21965	COG0789	Transcriptional regulator
HHJ45_21970	COG2207	Transcriptional regulator
HHJ45_21975	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HHJ45_21985	COG0629	single-stranded DNA binding
HHJ45_21990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHJ45_21995	COG2315	Protein conserved in bacteria
HHJ45_22000	COG0432	Pfam Uncharacterised protein family UPF0047
HHJ45_22005	COG3700	Belongs to the class B bacterial acid phosphatase family
HHJ45_22020	COG1448	Aminotransferase
HHJ45_22025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHJ45_22030	COG0305	Participates in initiation and elongation during chromosome replication
HHJ45_22035	COG0604	alcohol dehydrogenase
HHJ45_22045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ45_22055	COG0735	belongs to the Fur family
HHJ45_22060	COG3237	CsbD-like
HHJ45_22065	COG0534	Mate efflux family protein
HHJ45_22075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HHJ45_22110	COG3842	ATPase activity
HHJ45_22115	COG2182	Extracellular solute-binding protein
HHJ45_22120	COG1175	transmembrane transport
HHJ45_22125	COG3833	ABC-type maltose transport systems, permease component
HHJ45_22130	COG0477	Major facilitator Superfamily
HHJ45_22130	COG2814	Major facilitator Superfamily
HHJ45_22145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ45_22170	COG0527	aspartate kinase activity
HHJ45_22175	COG0542	response to heat
HHJ45_22180	COG3541	Predicted nucleotidyltransferase
HHJ45_22195	COG1187	pseudouridine synthase activity
HHJ45_22205	COG1283	sodium-dependent phosphate transmembrane transporter activity
HHJ45_22210	COG1410	methionine synthase
HHJ45_22210	COG0646	methionine synthase
HHJ45_22215	COG1414	Transcriptional regulator
HHJ45_22230	COG2224	Isocitrate lyase
HHJ45_22235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHJ45_22245	COG0456	acetyltransferase
HHJ45_22275	COG0151	Belongs to the GarS family
HHJ45_22280	COG2204	response regulator
HHJ45_22285	COG4191	Histidine kinase
HHJ45_22290	COG3678	ATP-independent chaperone mediated protein folding
HHJ45_22305	COG3068	Protein conserved in bacteria
HHJ45_22340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HHJ45_22345	COG2104	thiamine diphosphate biosynthetic process
HHJ45_22355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HHJ45_22395	COG0250	Participates in transcription elongation, termination and antitermination
HHJ45_22400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HHJ45_22435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HHJ45_22435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HHJ45_22485	COG1309	transcriptional regulator
HHJ45_22495	COG0583	DNA-binding transcription factor activity
HHJ45_22500	COG2271	Major facilitator Superfamily
HHJ45_22505	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ45_22520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHJ45_22535	COG2194	sulfuric ester hydrolase activity
HHJ45_22540	COG2207	Transcriptional regulator
HHJ45_22545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_22550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ45_22555	COG1882	Formate acetyltransferase
HHJ45_22560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_22565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_22570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_22570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_22570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ45_22575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ45_22580	COG0371	Dehydrogenase
HHJ45_22585	COG3738	Protein conserved in bacteria
HHJ45_22590	COG0697	spore germination
HHJ45_22600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HHJ45_22605	COG0460	homoserine dehydrogenase
HHJ45_22605	COG0527	aspartate kinase activity
HHJ45_22610	COG0626	cystathionine gamma-synthase activity
HHJ45_22620	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHJ45_22665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHJ45_22670	COG1609	Transcriptional regulator
HHJ45_22675	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHJ45_22690	COG1575	Belongs to the MenA family. Type 1 subfamily
HHJ45_22705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HHJ45_22715	COG1494	fructose-1,6-bisphosphatase
HHJ45_22725	COG0589	response to stress
HHJ45_22730	COG3691	Protein conserved in bacteria
HHJ45_22735	COG3152	Membrane
HHJ45_22755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HHJ45_22770	COG3678	ATP-independent chaperone mediated protein folding
HHJ45_22775	COG0745	RESPONSE REGULATOR receiver
HHJ45_22780	COG2205	protein histidine kinase activity
HHJ45_22785	COG2258	MOSC domain
HHJ45_22845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_22850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_22850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ45_22855	COG1363	Peptidase, m42
HHJ45_22860	COG3711	transcriptional antiterminator
HHJ45_22860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ45_22880	COG0437	4 iron, 4 sulfur cluster binding
HHJ45_22885	COG2864	formate dehydrogenase
HHJ45_22895	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ45_22900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ45_22910	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HHJ45_22920	COG0456	acetyltransferase
HHJ45_22935	COG1011	Hydrolase
HHJ45_22940	COG1349	DNA-binding transcription factor activity
HHJ45_22945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_22950	COG2084	Dehydrogenase
HHJ45_22955	COG3684	Belongs to the aldolase LacD family
HHJ45_22960	COG2942	2-epimerase
HHJ45_22965	COG2017	converts alpha-aldose to the beta-anomer
HHJ45_22970	COG1501	Belongs to the glycosyl hydrolase 31 family
HHJ45_22975	COG2211	Major facilitator Superfamily
HHJ45_22980	COG2211	Major facilitator Superfamily
HHJ45_22985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HHJ45_22990	COG2271	Major facilitator Superfamily
HHJ45_22995	COG1082	Xylose isomerase domain protein TIM barrel
HHJ45_23000	COG2188	Transcriptional regulator
HHJ45_23010	COG0174	glutamine synthetase
HHJ45_23015	COG3852	Histidine kinase
HHJ45_23020	COG2204	response regulator
HHJ45_23030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HHJ45_23045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHJ45_23045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHJ45_23050	COG0204	Acyl-transferase
HHJ45_23075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHJ45_23080	COG3084	Protein conserved in bacteria
HHJ45_23085	COG0746	molybdenum cofactor guanylyltransferase activity
HHJ45_23090	COG1763	Mo-molybdopterin cofactor biosynthetic process
HHJ45_23120	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HHJ45_23125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HHJ45_23130	COG1739	Uncharacterized protein family UPF0029
HHJ45_23150	COG0543	2 iron, 2 sulfur cluster binding
HHJ45_23155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HHJ45_23160	COG0250	Participates in transcription elongation, termination and antitermination
HHJ45_23170	COG0805	protein transport
HHJ45_23175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHJ45_23180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHJ45_23190	COG3165	ubiquinone biosynthetic process from chorismate
HHJ45_23200	COG1322	Protein conserved in bacteria
HHJ45_23205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HHJ45_23210	COG0412	Dienelactone hydrolase
HHJ45_23220	COG0583	DNA-binding transcription factor activity
HHJ45_23225	COG0697	spore germination
HHJ45_23230	COG0561	phosphatase activity
HHJ45_23235	COG2267	carboxylic ester hydrolase activity
HHJ45_23240	COG1280	lysine exporter protein (LysE YggA)
HHJ45_23245	COG1280	lysine exporter protein (LysE YggA)
HHJ45_23250	COG0514	ATP-dependent DNA helicase (RecQ)
HHJ45_23255	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HHJ45_23260	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ45_23265	COG2962	Rard protein
HHJ45_23290	COG0598	Magnesium transport protein CorA
HHJ45_23295	COG3698	Phosphodiester glycosidase
HHJ45_23300	COG0210	DNA helicase
HHJ45_23305	COG1011	Hydrolase
HHJ45_23315	COG3159	Protein conserved in bacteria
HHJ45_23325	COG5567	small periplasmic lipoprotein
HHJ45_23350	COG3072	Adenylate cyclase
HHJ45_23360	COG1587	Uroporphyrinogen-III synthase
HHJ45_23365	COG2959	enzyme of heme biosynthesis
HHJ45_23370	COG3071	HemY protein
HHJ45_23375	COG3119	arylsulfatase activity
HHJ45_23380	COG0641	radical SAM
HHJ45_23405	COG1113	amino acid transport
HHJ45_23425	COG2244	polysaccharide biosynthetic process
HHJ45_23430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HHJ45_23435	COG0456	acetyltransferase
HHJ45_23440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHJ45_23445	COG1088	dTDP-glucose 4,6-dehydratase activity
HHJ45_23450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HHJ45_23455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HHJ45_23460	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HHJ45_23465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHJ45_23470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHJ45_23480	COG3118	belongs to the thioredoxin family
HHJ45_23495	COG0210	DNA helicase
HHJ45_23500	COG3692	DNA binding
HHJ45_23505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ45_23515	COG0583	DNA-binding transcription factor activity
HHJ45_23525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ45_23535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HHJ45_23540	COG3978	acetolactate synthase activity
HHJ45_23560	COG0606	chelatase, subunit chli
HHJ45_23565	COG3085	chromosome segregation
HHJ45_23605	COG2186	Transcriptional regulator
HHJ45_23610	COG0477	Major facilitator Superfamily
HHJ45_23615	COG1609	Transcriptional regulator
HHJ45_23620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ45_23625	COG1879	ABC-type sugar transport system periplasmic component
HHJ45_23630	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ45_23635	COG1129	ABC transporter
HHJ45_23665	COG1522	sequence-specific DNA binding
HHJ45_23670	COG0716	FMN binding
HHJ45_23685	COG3312	ion transport
HHJ45_23735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HHJ45_23750	COG3188	usher protein
HHJ45_23760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HHJ45_23765	COG0573	inorganic phosphate transmembrane transporter activity
HHJ45_23770	COG0581	inorganic phosphate transmembrane transporter activity
HHJ45_23775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HHJ45_23780	COG0704	Plays a role in the regulation of phosphate uptake
HHJ45_23785	COG3711	transcriptional antiterminator
HHJ45_23790	COG2190	(PTS) system
HHJ45_23790	COG1263	PTS System
HHJ45_23790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ45_23795	COG2723	6-phospho-beta-galactosidase activity
HHJ45_23805	COG2382	esterase
HHJ45_23810	COG0363	glucosamine-6-phosphate deaminase activity
HHJ45_23815	COG3196	Protein conserved in bacteria
HHJ45_23825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ45_23830	COG2252	PERMEase
HHJ45_23835	COG0431	NADPH-dependent FMN reductase
HHJ45_23840	COG2091	lysine biosynthetic process via aminoadipic acid
HHJ45_23855	COG0814	amino acid
HHJ45_23940	COG3344	reverse transcriptase
HHJ45_23970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ45_23980	COG1538	Outer membrane efflux protein
HHJ45_24040	COG2382	esterase
HHJ45_24045	COG2819	hydrolase of the alpha beta superfamily
HHJ45_24055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ45_24105	COG0446	pyridine nucleotide-disulphide oxidoreductase
HHJ45_24105	COG1902	pentaerythritol trinitrate reductase activity
HHJ45_24250	COG3300	MHYT domain
HHJ45_24250	COG5001	Diguanylate cyclase
HHJ45_24325	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HHJ45_24530	COG1475	DNA binding
HHJ45_24655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHJ45_24670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HHJ45_24675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HHJ45_24680	COG1121	(ABC) transporter
HHJ45_24855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ45_24905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHJ45_24990	COG0629	single-stranded DNA binding