locus-tag	class	description
FORMB_00010	COG0592	DNA-directed DNA polymerase activity
FORMB_00100	COG0488	(ABC) transporter
FORMB_00120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORMB_00130	COG0300	oxidoreductase activity
FORMB_00260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORMB_00270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORMB_00280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORMB_00280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORMB_00290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORMB_00300	COG1078	dGTPase activity
FORMB_00310	COG2204	response regulator
FORMB_00330	COG0686	Belongs to the AlaDH PNT family
FORMB_00360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORMB_00370	COG1522	sequence-specific DNA binding
FORMB_00430	COG0012	GTP binding
FORMB_00440	COG4206	TonB-dependent receptor
FORMB_00440	COG1629	transport
FORMB_00450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORMB_00470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORMB_00480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORMB_00520	COG1136	(ABC) transporter
FORMB_00540	COG1234	tRNA 3'-trailer cleavage
FORMB_00560	COG0540	Belongs to the ATCase OTCase family
FORMB_00570	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FORMB_00590	COG0730	response to heat
FORMB_00600	COG0247	lactate metabolic process
FORMB_00600	COG0277	FAD linked oxidase domain protein
FORMB_00660	COG1522	sequence-specific DNA binding
FORMB_00670	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORMB_00680	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORMB_00710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORMB_00720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORMB_00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORMB_00760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORMB_00780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORMB_00810	COG0009	L-threonylcarbamoyladenylate synthase
FORMB_00820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORMB_00830	COG1611	Belongs to the LOG family
FORMB_00870	COG0450	alkyl hydroperoxide reductase
FORMB_00900	COG3361	conserved protein (COG2071)
FORMB_00940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORMB_00960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORMB_00970	COG2270	Major facilitator Superfamily
FORMB_00990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORMB_01000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORMB_01040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORMB_01050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORMB_01090	COG2234	aminopeptidase activity
FORMB_01110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORMB_01120	COG0626	cystathionine gamma-synthase activity
FORMB_01140	COG1373	ATPase (AAA superfamily
FORMB_01150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORMB_01160	COG1333	cytochrome c biogenesis protein
FORMB_01160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORMB_01190	COG0424	maF-like protein
FORMB_01210	COG0037	tRNA processing
FORMB_01220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORMB_01230	COG0513	Belongs to the DEAD box helicase family
FORMB_01250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORMB_01260	COG1522	sequence-specific DNA binding
FORMB_01440	COG0492	ferredoxin-NADP+ reductase activity
FORMB_01450	COG0572	uridine kinase
FORMB_01480	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORMB_01480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORMB_01490	COG1192	Involved in chromosome partitioning
FORMB_01500	COG1192	Involved in chromosome partitioning
FORMB_01510	COG1475	DNA binding
FORMB_01530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORMB_01540	COG0681	Belongs to the peptidase S26 family
FORMB_01600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORMB_01620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORMB_01640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORMB_01670	COG0105	UTP biosynthetic process
FORMB_01680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORMB_01700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORMB_01710	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORMB_01810	COG0804	urea catabolic process
FORMB_01820	COG1228	amidohydrolase
FORMB_01830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORMB_01840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORMB_01860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORMB_01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORMB_01930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORMB_01950	COG3956	TIGRFAM MazG family protein
FORMB_01970	COG1404	Belongs to the peptidase S8 family
FORMB_01980	COG0482	sulfurtransferase activity
FORMB_01990	COG0706	membrane insertase activity
FORMB_02000	COG0504	CTP synthase activity
FORMB_02010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORMB_02020	COG0514	ATP-dependent DNA helicase (RecQ)
FORMB_02030	COG0517	IMP dehydrogenase activity
FORMB_02030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORMB_02040	COG0805	protein transport
FORMB_02070	COG1137	ATPase activity
FORMB_02080	COG2354	Protein conserved in bacteria
FORMB_02120	COG0488	(ABC) transporter
FORMB_02150	COG2096	Adenosyltransferase
FORMB_02170	COG0653	protein targeting
FORMB_02240	COG3655	Transcriptional regulator
FORMB_02310	COG0671	phosphoesterase, PA-phosphatase related
FORMB_02330	COG0534	Mate efflux family protein
FORMB_02350	COG0242	peptide deformylase activity
FORMB_02360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORMB_02370	COG1216	Glycosyl transferase, family 2
FORMB_02410	COG2264	protein methyltransferase activity
FORMB_02420	COG0463	Glycosyl transferase, family 2
FORMB_02430	COG0463	Glycosyl transferase, family 2
FORMB_02440	COG0726	polysaccharide deacetylase
FORMB_02460	COG0463	Glycosyl transferase, family 2
FORMB_02470	COG0438	transferase activity, transferring glycosyl groups
FORMB_02500	COG0617	tRNA 3'-terminal CCA addition
FORMB_02620	COG0556	nucleotide-excision repair
FORMB_02660	COG0517	IMP dehydrogenase activity
FORMB_02680	COG0045	succinate-CoA ligase (ADP-forming) activity
FORMB_02700	COG0019	diaminopimelate decarboxylase activity
FORMB_02710	COG1278	Cold shock
FORMB_02830	COG3119	arylsulfatase activity
FORMB_02850	COG1629	transport
FORMB_02850	COG4206	TonB-dependent receptor
FORMB_02900	COG3537	Alpha-1,2-mannosidase
FORMB_02920	COG3119	arylsulfatase activity
FORMB_02930	COG3119	arylsulfatase activity
FORMB_02960	COG1482	cell wall glycoprotein biosynthetic process
FORMB_02980	COG3537	Alpha-1,2-mannosidase
FORMB_02990	COG3119	arylsulfatase activity
FORMB_03010	COG3119	arylsulfatase activity
FORMB_03020	COG0584	glycerophosphoryl diester phosphodiesterase
FORMB_03040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORMB_03140	COG4771	TonB-dependent receptor
FORMB_03160	COG0628	permease
FORMB_03170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORMB_03180	COG2274	protein secretion by the type I secretion system
FORMB_03300	COG1505	serine-type exopeptidase activity
FORMB_03310	COG1770	oligopeptidase
FORMB_03340	COG0165	Argininosuccinate lyase
FORMB_03350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORMB_03360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORMB_03380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORMB_03390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORMB_03400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORMB_03410	COG0137	argininosuccinate synthase activity
FORMB_03520	COG0167	dihydroorotate dehydrogenase activity
FORMB_03530	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORMB_03540	COG1862	Preprotein translocase
FORMB_03560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORMB_03570	COG1132	(ABC) transporter
FORMB_03590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORMB_03630	COG0519	Catalyzes the synthesis of GMP from XMP
FORMB_03630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORMB_03640	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FORMB_03650	COG1943	Transposase
FORMB_03660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORMB_03670	COG0552	protein localization to endoplasmic reticulum
FORMB_03690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORMB_03700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORMB_03710	COG1058	Belongs to the CinA family
FORMB_03710	COG1546	Belongs to the CinA family
FORMB_03720	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORMB_03760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORMB_03820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORMB_03830	COG0326	Molecular chaperone. Has ATPase activity
FORMB_03850	COG1073	alpha beta
FORMB_03900	COG1482	cell wall glycoprotein biosynthetic process
FORMB_03920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FORMB_03990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORMB_04000	COG2890	protein-(glutamine-N5) methyltransferase activity
FORMB_04030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORMB_04030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORMB_04040	COG1011	Hydrolase
FORMB_04050	COG1739	Uncharacterized protein family UPF0029
FORMB_04070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORMB_04080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORMB_04110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORMB_04120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORMB_04130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORMB_04150	COG0336	Belongs to the RNA methyltransferase TrmD family
FORMB_04160	COG0335	large ribosomal subunit rRNA binding
FORMB_04200	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORMB_04230	COG0596	Alpha beta hydrolase
FORMB_04340	COG1368	sulfuric ester hydrolase activity
FORMB_04370	COG2373	Large extracellular alpha-helical protein
FORMB_04380	COG4953	penicillin-binding protein 1C
FORMB_04470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORMB_04480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FORMB_04490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORMB_04500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORMB_04540	COG0305	Participates in initiation and elongation during chromosome replication
FORMB_04550	COG0825	malonyl-CoA metabolic process
FORMB_04580	COG0343	queuine tRNA-ribosyltransferase activity
FORMB_04610	COG3959	Transketolase, thiamine diphosphate binding domain
FORMB_04620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORMB_04650	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FORMB_04660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORMB_05020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORMB_05030	COG0714	Associated with various cellular activities
FORMB_05040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORMB_05070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORMB_05080	COG0516	GMP reductase activity
FORMB_05080	COG0517	IMP dehydrogenase activity
FORMB_05110	COG0463	Glycosyl transferase, family 2
FORMB_05150	COG2356	endonuclease I
FORMB_05180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORMB_05200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORMB_05220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORMB_05230	COG0512	Glutamine amidotransferase of anthranilate synthase
FORMB_05240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORMB_05250	COG0134	indole-3-glycerol-phosphate synthase activity
FORMB_05260	COG0135	phosphoribosylanthranilate isomerase activity
FORMB_05270	COG0133	tryptophan synthase activity
FORMB_05280	COG0159	tryptophan synthase activity
FORMB_05330	COG1396	sequence-specific DNA binding
FORMB_05410	COG2095	MarC family integral membrane protein
FORMB_05440	COG0784	Response regulator, receiver
FORMB_05440	COG2205	protein histidine kinase activity
FORMB_05470	COG0659	secondary active sulfate transmembrane transporter activity
FORMB_05540	COG4221	oxidoreductase activity
FORMB_05550	COG4628	conserved protein (DUF2132)
FORMB_05560	COG0513	Belongs to the DEAD box helicase family
FORMB_05570	COG3022	response to hydroperoxide
FORMB_05580	COG0564	pseudouridine synthase activity
FORMB_05590	COG2815	serine threonine protein kinase
FORMB_05590	COG0515	serine threonine protein kinase
FORMB_05600	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORMB_05610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORMB_05620	COG0659	secondary active sulfate transmembrane transporter activity
FORMB_05630	COG0494	nUDIX hydrolase
FORMB_05640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORMB_05670	COG0799	negative regulation of ribosome biogenesis
FORMB_05680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORMB_05700	COG4589	Belongs to the CDS family
FORMB_05710	COG0688	phosphatidylethanolamine metabolic process
FORMB_05730	COG0525	valine-tRNA ligase activity
FORMB_05750	COG3409	Peptidoglycan-binding domain 1 protein
FORMB_05750	COG0793	Belongs to the peptidase S41A family
FORMB_05760	COG0436	Aminotransferase
FORMB_05770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORMB_05780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORMB_05820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORMB_05830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORMB_05850	COG1663	tetraacyldisaccharide 4'-kinase activity
FORMB_05860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORMB_05890	COG3844	kynureninase activity
FORMB_05900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORMB_05930	COG1028	Short-chain dehydrogenase reductase Sdr
FORMB_05940	COG0662	Cupin 2, conserved barrel domain protein
FORMB_05990	COG3340	Belongs to the peptidase S51 family
FORMB_06010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORMB_06050	COG2226	methyltransferase
FORMB_06070	COG2274	protein secretion by the type I secretion system
FORMB_06110	COG1477	protein flavinylation
FORMB_06150	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORMB_06160	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORMB_06170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORMB_06180	COG1805	sodium ion transport
FORMB_06190	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORMB_06260	COG0357	Ribosomal RNA small subunit methyltransferase G
FORMB_06270	COG3239	Fatty acid desaturase
FORMB_06300	COG0569	domain protein
FORMB_06310	COG2226	methyltransferase
FORMB_06330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORMB_06360	COG0191	fructose-bisphosphate aldolase activity
FORMB_06370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORMB_06390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORMB_06400	COG1185	polyribonucleotide nucleotidyltransferase activity
FORMB_06410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORMB_06420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORMB_06460	COG5434	Belongs to the glycosyl hydrolase 28 family
FORMB_06500	COG2244	polysaccharide biosynthetic process
FORMB_06510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORMB_06530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORMB_06540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORMB_06590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORMB_06600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORMB_06610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORMB_06730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORMB_06760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORMB_06770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORMB_06780	COG0772	Belongs to the SEDS family
FORMB_06790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORMB_06800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORMB_06810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORMB_06820	COG0768	penicillin binding
FORMB_06840	COG0275	rRNA processing
FORMB_06850	COG2001	Belongs to the MraZ family
FORMB_06870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORMB_06880	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORMB_06890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORMB_06900	COG1127	ABC transporter
FORMB_06940	COG0018	arginyl-trna synthetase
FORMB_06960	COG1834	amidinotransferase
FORMB_06980	COG0148	phosphopyruvate hydratase activity
FORMB_06990	COG0505	Belongs to the CarA family
FORMB_07010	COG0203	ribosomal protein L17
FORMB_07020	COG0202	RNA polymerase activity
FORMB_07030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORMB_07040	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORMB_07050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORMB_07060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORMB_07070	COG0201	protein transport
FORMB_07080	COG0200	Binds to the 23S rRNA
FORMB_07090	COG1841	ribosomal large subunit assembly
FORMB_07100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORMB_07120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORMB_07130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORMB_07140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORMB_07150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORMB_07160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORMB_07170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORMB_07180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORMB_07190	COG0255	Belongs to the universal ribosomal protein uL29 family
FORMB_07200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORMB_07210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORMB_07220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORMB_07230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORMB_07240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORMB_07250	COG0089	rRNA binding
FORMB_07260	COG0088	Forms part of the polypeptide exit tunnel
FORMB_07270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORMB_07290	COG3325	Belongs to the glycosyl hydrolase 18 family
FORMB_07290	COG3469	chitinase activity
FORMB_07300	COG3325	Belongs to the glycosyl hydrolase 18 family
FORMB_07300	COG3469	chitinase activity
FORMB_07310	COG0051	transcription antitermination factor activity, RNA binding
FORMB_07320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORMB_07330	COG0049	tRNA binding
FORMB_07340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORMB_07360	COG4206	TonB-dependent receptor
FORMB_07360	COG1629	transport
FORMB_07380	COG1629	transport
FORMB_07380	COG4206	TonB-dependent receptor
FORMB_07430	COG4206	TonB-dependent receptor
FORMB_07430	COG1629	transport
FORMB_07500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORMB_07560	COG2003	Belongs to the UPF0758 family
FORMB_07570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORMB_07590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORMB_07600	COG0563	adenylate kinase activity
FORMB_07610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORMB_07620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORMB_07630	COG0339	signal peptide processing
FORMB_07650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORMB_07650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORMB_07660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORMB_07690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORMB_07720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORMB_07750	COG1704	LemA family
FORMB_07770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FORMB_07780	COG1160	GTP binding
FORMB_07930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORMB_07940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORMB_07970	COG0527	aspartate kinase activity
FORMB_08110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORMB_08140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORMB_08150	COG2239	Acts as a magnesium transporter
FORMB_08160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORMB_08190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORMB_08200	COG0196	riboflavin kinase activity
FORMB_08220	COG0193	aminoacyl-tRNA hydrolase activity
FORMB_08230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORMB_08240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORMB_08420	COG3177	Filamentation induced by cAMP protein fic
FORMB_08500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORMB_08510	COG2226	methyltransferase
FORMB_08530	COG1215	transferase activity, transferring glycosyl groups
FORMB_08560	COG0463	Glycosyl transferase, family 2
FORMB_08570	COG1215	transferase activity, transferring glycosyl groups
FORMB_08590	COG1187	pseudouridine synthase activity
FORMB_08630	COG2081	HI0933 family
FORMB_08670	COG0784	Response regulator, receiver
FORMB_08690	COG4251	negative regulation of phosphorylation
FORMB_08710	COG3279	Response regulator of the LytR AlgR family
FORMB_08790	COG0745	RESPONSE REGULATOR receiver
FORMB_08890	COG3483	tryptophan 2,3-dioxygenase activity
FORMB_08910	COG2151	metal-sulfur cluster biosynthetic enzyme
FORMB_08920	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FORMB_08950	COG2234	aminopeptidase activity
FORMB_08960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORMB_08970	COG3938	Belongs to the proline racemase family
FORMB_09030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORMB_09040	COG2318	DinB family
FORMB_09050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORMB_09070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORMB_09080	COG3291	Pkd domain containing protein
FORMB_09090	COG2363	Small membrane protein
FORMB_09110	COG1522	sequence-specific DNA binding
FORMB_09140	COG0495	leucyl-tRNA aminoacylation
FORMB_09150	COG2177	Part of the ABC transporter FtsEX involved in
FORMB_09170	COG1968	undecaprenyl-diphosphatase activity
FORMB_09180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORMB_09190	COG0519	Catalyzes the synthesis of GMP from XMP
FORMB_09200	COG2326	polyphosphate kinase activity
FORMB_09210	COG2326	polyphosphate kinase activity
FORMB_09220	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORMB_09260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORMB_09340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FORMB_09360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORMB_09370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORMB_09380	COG0612	Peptidase, M16
FORMB_09390	COG0612	Peptidase, M16
FORMB_09420	COG0006	proline dipeptidase activity
FORMB_09450	COG1053	succinate dehydrogenase
FORMB_09460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORMB_09480	COG1040	competence protein
FORMB_09490	COG0423	glycine-tRNA ligase activity
FORMB_09620	COG0708	Exodeoxyribonuclease III
FORMB_09630	COG1360	Flagellar Motor Protein
FORMB_09640	COG0667	Aldo Keto reductase
FORMB_09650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORMB_09660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORMB_09710	COG1490	D-aminoacyl-tRNA deacylase activity
FORMB_09720	COG1162	GTPase activity
FORMB_09770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORMB_09780	COG0287	Prephenate dehydrogenase
FORMB_09790	COG0436	Aminotransferase
FORMB_09800	COG0077	Prephenate dehydratase
FORMB_09830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORMB_09900	COG1428	Deoxynucleoside kinase
FORMB_09910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FORMB_09930	COG0022	dehydrogenase e1 component
FORMB_09930	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORMB_09940	COG2086	electron transfer activity
FORMB_09950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORMB_09970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORMB_09980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORMB_09990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORMB_10000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORMB_10010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORMB_10090	COG1629	transport
FORMB_10090	COG4206	TonB-dependent receptor
FORMB_10130	COG3275	phosphorelay sensor kinase activity
FORMB_10160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORMB_10180	COG3239	Fatty acid desaturase
FORMB_10330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORMB_10340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORMB_10350	COG1428	Deoxynucleoside kinase
FORMB_10380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORMB_10400	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORMB_10410	COG0596	Alpha beta hydrolase
FORMB_10420	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORMB_10440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORMB_10460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORMB_10500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORMB_10560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORMB_10570	COG0439	Biotin carboxylase
FORMB_10580	COG0511	ligase activity, forming carbon-carbon bonds
FORMB_10590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORMB_10600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORMB_10620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORMB_10640	COG1970	mechanosensitive ion channel activity
FORMB_10750	COG0534	Mate efflux family protein
FORMB_10760	COG0720	synthase
FORMB_10770	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORMB_10820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORMB_10820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORMB_10840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORMB_10860	COG0668	transmembrane transport
FORMB_10890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORMB_10900	COG1136	(ABC) transporter
FORMB_10900	COG0577	efflux transmembrane transporter activity
FORMB_10910	COG0577	efflux transmembrane transporter activity
FORMB_10910	COG1136	(ABC) transporter
FORMB_10920	COG1136	(ABC) transporter
FORMB_10950	COG2322	membrane
FORMB_10960	COG1999	signal sequence binding
FORMB_11010	COG0109	protoheme IX farnesyltransferase activity
FORMB_11030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORMB_11040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORMB_11050	COG0052	Belongs to the universal ribosomal protein uS2 family
FORMB_11060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORMB_11080	COG0528	UMP kinase activity
FORMB_11090	COG0233	cytoplasmic translational termination
FORMB_11110	COG0017	Asparaginyl-tRNA synthetase
FORMB_11120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORMB_11130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORMB_11140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORMB_11170	COG4771	TonB-dependent receptor
FORMB_11180	COG1381	Involved in DNA repair and RecF pathway recombination
FORMB_11200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORMB_11260	COG1561	YicC-like family, N-terminal region
FORMB_11270	COG0194	GDP metabolic process
FORMB_11280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORMB_11310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORMB_11320	COG0346	lactoylglutathione lyase activity
FORMB_11590	COG2353	YceI-like domain
FORMB_11730	COG2885	chlorophyll binding
FORMB_11730	COG3047	cAMP biosynthetic process
FORMB_11780	COG3341	Caulimovirus viroplasmin
FORMB_11780	COG0328	RNA-DNA hybrid ribonuclease activity
FORMB_11800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORMB_11810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORMB_11820	COG0571	ribonuclease III activity
FORMB_11840	COG0469	pyruvate kinase activity
FORMB_11850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORMB_11860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORMB_11870	COG0440	acetolactate synthase activity
FORMB_11880	COG0028	Belongs to the TPP enzyme family
FORMB_11890	COG0129	dihydroxy-acid dehydratase activity
FORMB_11910	COG0070	glutamate synthase
FORMB_11910	COG0069	glutamate synthase activity
FORMB_11910	COG0067	glutamate synthase
FORMB_11930	COG0004	ammonium transporteR
FORMB_11950	COG0004	ammonium transporteR
FORMB_11960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORMB_11980	COG1012	belongs to the aldehyde dehydrogenase family
FORMB_12180	COG4989	oxidoreductase activity
FORMB_12190	COG0714	Associated with various cellular activities
FORMB_12220	COG2304	oxidoreductase activity
FORMB_12230	COG2304	oxidoreductase activity
FORMB_12280	COG0659	secondary active sulfate transmembrane transporter activity
FORMB_12310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORMB_12350	COG1435	thymidine kinase activity
FORMB_12360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORMB_12390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORMB_12400	COG3842	ATPase activity
FORMB_12430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORMB_12480	COG0557	exoribonuclease II activity
FORMB_12490	COG0698	ribose 5-phosphate isomerase
FORMB_12510	COG2153	protein acetylation
FORMB_12530	COG0793	Belongs to the peptidase S41A family
FORMB_12540	COG0594	ribonuclease P activity
FORMB_12580	COG0659	secondary active sulfate transmembrane transporter activity
FORMB_12600	COG0481	GTPase activity
FORMB_12610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORMB_12700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORMB_12710	COG0445	tRNA wobble uridine modification
FORMB_12740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORMB_12750	COG0126	phosphoglycerate kinase activity
FORMB_12760	COG1388	LysM domain
FORMB_12760	COG0791	NLP P60 protein
FORMB_12780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORMB_12850	COG1086	Polysaccharide biosynthesis protein
FORMB_12860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORMB_12890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORMB_12900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORMB_12920	COG1028	Short-chain dehydrogenase reductase Sdr
FORMB_12950	COG2089	acid synthase
FORMB_13010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORMB_13020	COG0438	transferase activity, transferring glycosyl groups
FORMB_13050	COG0151	Belongs to the GarS family
FORMB_13100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORMB_13160	COG0356	it plays a direct role in the translocation of protons across the membrane
FORMB_13170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORMB_13180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORMB_13190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORMB_13200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORMB_13220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORMB_13330	COG0756	dUTP diphosphatase activity
FORMB_13400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORMB_13400	COG0758	DNA mediated transformation
FORMB_13410	COG0180	Tryptophanyl-tRNA synthetase
FORMB_13470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORMB_13490	COG1774	PSP1 C-terminal conserved region
FORMB_13520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORMB_13580	COG4206	TonB-dependent receptor
FORMB_13580	COG1629	transport
FORMB_13670	COG0113	porphobilinogen synthase activity
FORMB_13680	COG0408	coproporphyrinogen oxidase activity
FORMB_13690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORMB_13700	COG0181	hydroxymethylbilane synthase activity
FORMB_13710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORMB_13730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORMB_13770	COG1024	Enoyl-CoA hydratase
FORMB_13830	COG4206	TonB-dependent receptor
FORMB_13830	COG1629	transport
FORMB_13870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORMB_13910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORMB_13920	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FORMB_13950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORMB_13970	COG0484	heat shock protein binding
FORMB_14020	COG1999	signal sequence binding
FORMB_14030	COG0750	zinc metalloprotease
FORMB_14060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORMB_14100	COG2217	Heavy metal translocating P-type atpase
FORMB_14130	COG0516	GMP reductase activity
FORMB_14130	COG0517	IMP dehydrogenase activity
FORMB_14180	COG0788	formyltetrahydrofolate deformylase activity
FORMB_14190	COG2827	Endonuclease containing a URI domain
FORMB_14210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORMB_14220	COG0156	8-amino-7-oxononanoate synthase activity
FORMB_14300	COG1595	DNA-templated transcription, initiation
FORMB_14320	COG1629	transport
FORMB_14320	COG4206	TonB-dependent receptor
FORMB_14340	COG2271	Major facilitator Superfamily
FORMB_14380	COG0793	Belongs to the peptidase S41A family
FORMB_14400	COG2095	MarC family integral membrane protein
FORMB_14430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORMB_14430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORMB_14560	COG1629	transport
FORMB_14560	COG4206	TonB-dependent receptor
FORMB_14580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORMB_14630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORMB_14660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORMB_14700	COG1309	transcriptional regulator
FORMB_14710	COG0142	geranyltranstransferase activity
FORMB_14780	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORMB_14840	COG1446	asparaginase
FORMB_14870	COG3118	belongs to the thioredoxin family
FORMB_14930	COG0779	Required for maturation of 30S ribosomal subunits
FORMB_14940	COG0195	Participates in both transcription termination and antitermination
FORMB_14950	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORMB_15000	COG0437	4 iron, 4 sulfur cluster binding
FORMB_15050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORMB_15060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORMB_15070	COG2255	four-way junction helicase activity
FORMB_15090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORMB_15100	COG0405	Gamma-glutamyltransferase
FORMB_15110	COG0281	malic enzyme
FORMB_15110	COG0280	phosphate acetyltransferase
FORMB_15120	COG0632	four-way junction helicase activity
FORMB_15140	COG0509	glycine decarboxylation via glycine cleavage system
FORMB_15210	COG0084	hydrolase, TatD family'
FORMB_15220	COG0252	asparaginase activity
FORMB_15240	COG0811	peptide transport
FORMB_15260	COG0848	biopolymer transport protein
FORMB_15300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORMB_15320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORMB_15330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORMB_15340	COG0189	ligase activity
FORMB_15350	COG0322	excinuclease ABC activity
FORMB_15390	COG3483	tryptophan 2,3-dioxygenase activity
FORMB_15410	COG0166	Belongs to the GPI family
FORMB_15440	COG2356	endonuclease I
FORMB_15640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORMB_15670	COG2151	metal-sulfur cluster biosynthetic enzyme
FORMB_15680	COG2166	iron-sulfur cluster assembly
FORMB_15700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORMB_15710	COG0719	Fe-S assembly protein
FORMB_15720	COG0396	ATPase activity
FORMB_15740	COG0719	Fe-S assembly protein
FORMB_15750	COG0316	Belongs to the HesB IscA family
FORMB_15760	COG1858	cytochrome C peroxidase
FORMB_15800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORMB_15830	COG0629	single-stranded DNA binding
FORMB_15850	COG0776	regulation of translation
FORMB_15860	COG1530	ribonuclease E activity
FORMB_15880	COG0473	3-isopropylmalate dehydrogenase activity
FORMB_15890	COG0066	3-isopropylmalate dehydratase activity
FORMB_15900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORMB_15910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORMB_15970	COG0175	sulfate reduction
FORMB_15980	COG0175	sulfate reduction
FORMB_15990	COG2895	sulfate adenylyltransferase (ATP) activity
FORMB_16010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORMB_16020	COG1648	precorrin-2 dehydrogenase activity
FORMB_16020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORMB_16030	COG0492	ferredoxin-NADP+ reductase activity
FORMB_16040	COG1410	methionine synthase
FORMB_16040	COG0646	methionine synthase
FORMB_16060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORMB_16100	COG0358	DNA primase activity
FORMB_16120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORMB_16150	COG0772	Belongs to the SEDS family
FORMB_16160	COG0768	penicillin binding
FORMB_16190	COG1077	Cell shape determining protein MreB Mrl
FORMB_16200	COG0138	bifunctional purine biosynthesis protein purh
FORMB_16320	COG0459	protein refolding
FORMB_16330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORMB_16370	COG3604	Transcriptional regulator
FORMB_16380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORMB_16420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORMB_16460	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORMB_16460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORMB_16480	COG0488	(ABC) transporter
FORMB_16580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORMB_17350	COG1476	TRANSCRIPTIONal
FORMB_17390	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORMB_17440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORMB_17440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORMB_17450	COG0730	response to heat
FORMB_17490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORMB_17500	COG0401	homolog of Blt101
FORMB_17510	COG0321	lipoyl(octanoyl) transferase activity
FORMB_17530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORMB_17660	COG0793	Belongs to the peptidase S41A family
FORMB_17730	COG0326	Molecular chaperone. Has ATPase activity
FORMB_17890	COG0385	Bile acid
FORMB_17960	COG1960	acyl-CoA dehydrogenase activity
FORMB_17970	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORMB_17990	COG0811	peptide transport
FORMB_18000	COG0848	biopolymer transport protein
FORMB_18020	COG0285	dihydrofolate synthase activity
FORMB_18090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORMB_18100	COG0295	cytidine deaminase activity
FORMB_18130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORMB_18140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORMB_18180	COG1028	Short-chain dehydrogenase reductase Sdr
FORMB_18190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORMB_18200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORMB_18240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORMB_18240	COG0662	Cupin 2, conserved barrel domain protein
FORMB_18260	COG0602	queuosine metabolic process
FORMB_18310	COG0367	asparagine synthase
FORMB_18320	COG0187	DNA topoisomerase II activity
FORMB_18350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORMB_18380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORMB_18390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FORMB_18400	COG0215	cysteine-tRNA ligase activity
FORMB_18410	COG0302	gtp cyclohydrolase
FORMB_18460	COG0442	prolyl-tRNA aminoacylation
FORMB_18480	COG0268	Binds directly to 16S ribosomal RNA
FORMB_18530	COG0101	tRNA pseudouridine synthase activity
FORMB_18540	COG1132	(ABC) transporter
FORMB_18550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORMB_18560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORMB_18610	COG0149	triose-phosphate isomerase activity
FORMB_18620	COG2264	protein methyltransferase activity
FORMB_18640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORMB_18640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORMB_18660	COG4974	Belongs to the 'phage' integrase family
FORMB_19150	COG0358	DNA primase activity
FORMB_19280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORMB_19310	COG0348	domain, Protein
FORMB_19330	COG2010	Cytochrome c
FORMB_19350	COG3278	Belongs to the heme-copper respiratory oxidase family
FORMB_19370	COG2217	Heavy metal translocating P-type atpase
FORMB_19390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORMB_19460	COG0463	Glycosyl transferase, family 2
FORMB_19470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FORMB_19500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORMB_19540	COG0745	RESPONSE REGULATOR receiver
FORMB_19550	COG5002	protein histidine kinase activity
FORMB_19560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORMB_19590	COG0489	protein tyrosine kinase activity
FORMB_19600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORMB_19610	COG0492	ferredoxin-NADP+ reductase activity
FORMB_19620	COG0633	Ferredoxin
FORMB_19650	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORMB_19660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORMB_19670	COG0228	four-way junction DNA binding
FORMB_19800	COG3177	Filamentation induced by cAMP protein fic
FORMB_19810	COG3177	Filamentation induced by cAMP protein fic
FORMB_19840	COG1946	Acyl-CoA thioesterase
FORMB_19870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORMB_19890	COG0792	nuclease activity
FORMB_19930	COG2329	Antibiotic biosynthesis monooxygenase
FORMB_19940	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORMB_19950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORMB_19950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORMB_20090	COG1609	Transcriptional regulator
FORMB_20140	COG0629	single-stranded DNA binding
FORMB_20170	COG3590	peptidase
FORMB_20220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FORMB_20270	COG1253	flavin adenine dinucleotide binding
FORMB_20280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORMB_20360	COG0823	Involved in the tonB-independent uptake of proteins
FORMB_20360	COG1506	peptidase
FORMB_20370	COG3104	oligopeptide transport
FORMB_20390	COG3104	oligopeptide transport
FORMB_20410	COG0658	competence protein
FORMB_20410	COG2333	competence protein COMEC
FORMB_20420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORMB_20440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORMB_20480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORMB_20500	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORMB_20510	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORMB_20510	COG1388	LysM domain
FORMB_20520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORMB_20610	COG2897	thiosulfate sulfurtransferase activity
FORMB_20660	COG0174	glutamine synthetase
FORMB_20680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORMB_20690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORMB_20700	COG0284	orotidine-5'-phosphate decarboxylase activity
FORMB_20720	COG1522	sequence-specific DNA binding
FORMB_20740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORMB_20780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORMB_20810	COG1090	epimerase
FORMB_20820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORMB_20830	COG0484	heat shock protein binding
FORMB_20840	COG1272	protein, Hemolysin III
FORMB_20880	COG0783	Belongs to the Dps family
FORMB_20960	COG4152	abc transporter atp-binding protein
FORMB_20970	COG1668	transmembrane transport
FORMB_21010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORMB_21050	COG2194	sulfuric ester hydrolase activity
FORMB_21070	COG1216	Glycosyl transferase, family 2
FORMB_21070	COG1442	glycosyl transferase family 8
FORMB_21090	COG2884	Cell division ATP-binding protein ftsE
FORMB_21120	COG3615	Tellurite resistance protein tehB
FORMB_21120	COG0500	methyltransferase
FORMB_21130	COG1115	amino acid carrier protein
FORMB_21160	COG3876	Protein conserved in bacteria
FORMB_21170	COG0577	efflux transmembrane transporter activity
FORMB_21250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORMB_21270	COG1115	amino acid carrier protein
FORMB_21290	COG1960	acyl-CoA dehydrogenase activity
FORMB_21300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORMB_21320	COG4974	Belongs to the 'phage' integrase family
FORMB_21330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORMB_21380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORMB_21420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORMB_21430	COG0081	regulation of translation
FORMB_21440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORMB_21450	COG0222	ribosome binding
FORMB_21460	COG0085	RNA polymerase activity
FORMB_21470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORMB_21500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORMB_21530	COG0737	Belongs to the 5'-nucleotidase family
FORMB_21560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORMB_21610	COG0497	DNA recombination
FORMB_21620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORMB_21660	COG0237	dephospho-CoA kinase activity
FORMB_21690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORMB_21700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORMB_21710	COG2176	DNA-directed DNA polymerase activity
FORMB_21740	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORMB_21750	COG0673	inositol 2-dehydrogenase activity
FORMB_21850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORMB_21870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORMB_21900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORMB_21910	COG2986	histidine ammonia-lyase
FORMB_21920	COG0542	response to heat
FORMB_21950	COG0791	NLP P60 protein
FORMB_21960	COG0183	Belongs to the thiolase family
FORMB_22070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORMB_22170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORMB_22170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORMB_22210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORMB_22320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORMB_22340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORMB_22350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORMB_22370	COG0205	6-phosphofructokinase activity
FORMB_22380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORMB_22400	COG0251	oxidation-reduction process
FORMB_22420	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORMB_22420	COG2247	cell wall binding repeat
FORMB_22430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORMB_22440	COG2181	nitrate reductase activity
FORMB_22440	COG0247	lactate metabolic process
FORMB_22460	COG2181	nitrate reductase activity
FORMB_22460	COG0247	lactate metabolic process
FORMB_22480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORMB_22540	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORMB_22600	COG1472	Belongs to the glycosyl hydrolase 3 family
FORMB_22610	COG0438	transferase activity, transferring glycosyl groups
FORMB_22620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORMB_22630	COG1301	dicarboxylic acid transport
FORMB_22770	COG3011	Protein conserved in bacteria
FORMB_22780	COG1193	negative regulation of DNA recombination
FORMB_22790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORMB_22810	COG0813	purine-nucleoside phosphorylase activity
FORMB_22840	COG0022	dehydrogenase e1 component
FORMB_22880	COG1228	amidohydrolase
FORMB_23000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORMB_23010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORMB_23030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORMB_23040	COG0156	8-amino-7-oxononanoate synthase activity
FORMB_23060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORMB_23130	COG1487	ribonuclease activity
FORMB_23150	COG0156	8-amino-7-oxononanoate synthase activity
FORMB_23220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORMB_23330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORMB_23340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORMB_23360	COG1234	tRNA 3'-trailer cleavage
FORMB_23380	COG0400	carboxylic ester hydrolase activity
FORMB_23420	COG1216	Glycosyl transferase, family 2
FORMB_23530	COG0339	signal peptide processing
FORMB_23540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORMB_23650	COG1960	acyl-CoA dehydrogenase activity
FORMB_23670	COG0183	Belongs to the thiolase family
FORMB_23690	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORMB_23690	COG1024	Enoyl-CoA hydratase
FORMB_23700	COG1846	Transcriptional regulator
FORMB_23750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORMB_23750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORMB_23770	COG1132	(ABC) transporter
FORMB_23780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORMB_23810	COG0254	rRNA binding
FORMB_23830	COG0747	negative chemotaxis
FORMB_23840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORMB_23890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORMB_23900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORMB_24000	COG4206	TonB-dependent receptor
FORMB_24010	COG0793	Belongs to the peptidase S41A family
FORMB_24010	COG3409	Peptidoglycan-binding domain 1 protein
FORMB_24020	COG1191	sigma factor activity
FORMB_24100	COG2827	Endonuclease containing a URI domain
FORMB_24130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORMB_24140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORMB_24160	COG1295	ribonuclease BN
FORMB_24170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORMB_24180	COG3279	Response regulator of the LytR AlgR family
FORMB_24190	COG0360	Binds together with S18 to 16S ribosomal RNA
FORMB_24200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FORMB_24210	COG0359	binds to the 23S rRNA
FORMB_24260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORMB_24340	COG0124	histidyl-tRNA synthetase
FORMB_24430	COG1678	Uncharacterized ACR, COG1678
FORMB_24440	COG0776	regulation of translation
FORMB_24450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORMB_24460	COG0514	ATP-dependent DNA helicase (RecQ)
FORMB_24500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORMB_24510	COG2824	Alkylphosphonate utilization operon protein PhnA
FORMB_24520	COG0415	Belongs to the DNA photolyase family
FORMB_24560	COG0386	Belongs to the glutathione peroxidase family
FORMB_24590	COG0302	gtp cyclohydrolase
FORMB_24620	COG3046	protein related to deoxyribodipyrimidine photolyase
FORMB_24660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORMB_24740	COG2211	Major facilitator Superfamily
FORMB_24760	COG0606	chelatase, subunit chli
FORMB_24770	COG1012	belongs to the aldehyde dehydrogenase family
FORMB_24780	COG0564	pseudouridine synthase activity
FORMB_24790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORMB_24810	COG0443	Heat shock 70 kDa protein
FORMB_24840	COG2050	protein possibly involved in aromatic compounds catabolism
FORMB_24850	COG1169	isochorismate synthase
FORMB_24860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORMB_24880	COG2996	Protein conserved in bacteria
FORMB_24900	COG1575	Belongs to the MenA family. Type 1 subfamily
FORMB_24910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FORMB_24920	COG4948	Mandelate Racemase Muconate Lactonizing
FORMB_24950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORMB_24960	COG1741	Belongs to the pirin family
FORMB_24980	COG0488	(ABC) transporter
FORMB_24990	COG3813	Protein conserved in bacteria
FORMB_25020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORMB_25030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORMB_25050	COG1012	belongs to the aldehyde dehydrogenase family
FORMB_25300	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORMB_25320	COG0740	serine-type endopeptidase activity
FORMB_25380	COG2369	cell adhesion
FORMB_25660	COG1104	cysteine desulfurase activity
FORMB_25710	COG1418	mRNA catabolic process
FORMB_25720	COG4974	Belongs to the 'phage' integrase family
FORMB_25820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORMB_25830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORMB_25830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORMB_25860	COG1674	ftsk spoiiie
FORMB_25880	COG0259	pyridoxamine-phosphate oxidase activity
FORMB_25910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORMB_25950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORMB_25960	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORMB_25980	COG1454	alcohol dehydrogenase
FORMB_26000	COG0217	transcriptional regulatory protein
FORMB_26020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORMB_26030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORMB_26040	COG0083	homoserine kinase activity
FORMB_26050	COG0460	homoserine dehydrogenase
FORMB_26050	COG0527	aspartate kinase activity
FORMB_26080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORMB_26160	COG1028	Short-chain dehydrogenase reductase Sdr
FORMB_26190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORMB_26200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORMB_26210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORMB_26220	COG0131	Imidazoleglycerol-phosphate dehydratase
FORMB_26240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORMB_26250	COG0107	imidazoleglycerol-phosphate synthase activity
FORMB_26260	COG0140	phosphoribosyl-ATP diphosphatase activity
FORMB_26260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORMB_26270	COG0101	tRNA pseudouridine synthase activity
FORMB_26300	COG0668	transmembrane transport
FORMB_26350	COG1899	peptidyl-lysine modification to peptidyl-hypusine
FORMB_26360	COG0010	Belongs to the arginase family
FORMB_26370	COG1166	arginine decarboxylase activity
FORMB_26380	COG4771	TonB-dependent receptor
FORMB_26430	COG2963	transposase activity
FORMB_26460	COG0415	Belongs to the DNA photolyase family
FORMB_26470	COG0415	Belongs to the DNA photolyase family
FORMB_26540	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FORMB_26570	COG0484	heat shock protein binding
FORMB_26620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORMB_26620	COG0116	Belongs to the methyltransferase superfamily
FORMB_26670	COG1363	Peptidase, m42
FORMB_26680	COG0494	nUDIX hydrolase
FORMB_26690	COG2814	Major facilitator Superfamily
FORMB_26700	COG2267	carboxylic ester hydrolase activity
FORMB_26710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORMB_26740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORMB_26750	COG1702	phosphate starvation-inducible protein PhoH