locus-tag	class	description
Gdia_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Gdia_0002	COG0592	DNA-directed DNA polymerase activity
Gdia_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Gdia_0004	COG0187	DNA topoisomerase II activity
Gdia_0006	COG0546	phosphoglycolate phosphatase activity
Gdia_0007	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Gdia_0008	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Gdia_0011	COG2022	thiamine diphosphate biosynthetic process
Gdia_0016	COG2010	Cytochrome c
Gdia_0016	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Gdia_0018	COG0531	amino acid
Gdia_0020	COG1968	undecaprenyl-diphosphatase activity
Gdia_0023	COG0586	Pfam SNARE associated Golgi protein
Gdia_0024	COG2951	lytic endotransglycosylase activity
Gdia_0026	COG1686	Belongs to the peptidase S11 family
Gdia_0027	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Gdia_0028	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Gdia_0030	COG0084	hydrolase, TatD family'
Gdia_0032	COG2766	serine protein kinase
Gdia_0033	COG2718	Belongs to the UPF0229 family
Gdia_0034	COG2719	SpoVR family
Gdia_0041	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Gdia_0041	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Gdia_0044	COG0745	RESPONSE REGULATOR receiver
Gdia_0046	COG0322	excinuclease ABC activity
Gdia_0047	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Gdia_0049	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Gdia_0050	COG0314	molybdopterin synthase activity
Gdia_0051	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Gdia_0051	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Gdia_0052	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Gdia_0054	COG0142	geranyltranstransferase activity
Gdia_0055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Gdia_0056	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Gdia_0060	COG1605	Chorismate mutase
Gdia_0060	COG0287	Prephenate dehydrogenase
Gdia_0061	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Gdia_0064	COG1196	nuclear chromosome segregation
Gdia_0068	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Gdia_0069	COG1702	phosphate starvation-inducible protein PhoH
Gdia_0070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Gdia_0071	COG0729	surface antigen
Gdia_0078	COG3781	membrane
Gdia_0079	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Gdia_0080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Gdia_0081	COG0432	Pfam Uncharacterised protein family UPF0047
Gdia_0082	COG0180	Tryptophanyl-tRNA synthetase
Gdia_0083	COG0545	Peptidyl-prolyl cis-trans isomerase
Gdia_0084	COG0137	argininosuccinate synthase activity
Gdia_0085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Gdia_0086	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Gdia_0087	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Gdia_0089	COG1722	exodeoxyribonuclease VII activity
Gdia_0091	COG1940	carbohydrate kinase activity
Gdia_0092	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Gdia_0094	COG3706	GGDEF domain
Gdia_0098	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gdia_0101	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Gdia_0103	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gdia_0104	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Gdia_0105	COG1278	Cold shock
Gdia_0107	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Gdia_0108	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Gdia_0109	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Gdia_0110	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0114	COG0076	glutamate decarboxylase activity
Gdia_0117	COG0484	heat shock protein binding
Gdia_0120	COG0321	lipoyl(octanoyl) transferase activity
Gdia_0127	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Gdia_0130	COG2706	6-phosphogluconolactonase activity
Gdia_0131	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Gdia_0132	COG0527	aspartate kinase activity
Gdia_0133	COG2070	2-Nitropropane dioxygenase
Gdia_0135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Gdia_0136	COG0124	histidyl-tRNA synthetase
Gdia_0137	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Gdia_0139	COG2890	protein-(glutamine-N5) methyltransferase activity
Gdia_0141	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Gdia_0142	COG0156	8-amino-7-oxononanoate synthase activity
Gdia_0144	COG4106	trans-aconitate 2-methyltransferase activity
Gdia_0144	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Gdia_0145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Gdia_0146	COG0303	'Molybdopterin
Gdia_0147	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Gdia_0149	COG0148	phosphopyruvate hydratase activity
Gdia_0151	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Gdia_0152	COG0504	CTP synthase activity
Gdia_0154	COG0149	triose-phosphate isomerase activity
Gdia_0156	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Gdia_0158	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Gdia_0159	COG0134	indole-3-glycerol-phosphate synthase activity
Gdia_0160	COG0315	cyclic pyranopterin monophosphate synthase activity
Gdia_0161	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gdia_0162	COG0022	dehydrogenase e1 component
Gdia_0162	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gdia_0163	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gdia_0164	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Gdia_0165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Gdia_0168	COG3585	molybdate ion transport
Gdia_0173	COG0840	transmembrane signaling receptor activity
Gdia_0176	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Gdia_0177	COG0741	lytic transglycosylase activity
Gdia_0179	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Gdia_0181	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Gdia_0184	COG0047	phosphoribosylformylglycinamidine synthase activity
Gdia_0185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Gdia_0186	COG0271	Belongs to the BolA IbaG family
Gdia_0187	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Gdia_0189	COG0792	nuclease activity
Gdia_0192	COG0628	permease
Gdia_0193	COG2897	thiosulfate sulfurtransferase activity
Gdia_0194	COG0626	cystathionine gamma-synthase activity
Gdia_0196	COG0606	chelatase, subunit chli
Gdia_0197	COG1476	TRANSCRIPTIONal
Gdia_0204	COG1695	Transcriptional regulator
Gdia_0208	COG2003	Belongs to the UPF0758 family
Gdia_0209	COG0546	phosphoglycolate phosphatase activity
Gdia_0210	COG2003	Belongs to the UPF0758 family
Gdia_0211	COG0210	DNA helicase
Gdia_0212	COG2264	protein methyltransferase activity
Gdia_0214	COG0473	3-isopropylmalate dehydrogenase activity
Gdia_0215	COG2351	hydroxyisourate hydrolase activity
Gdia_0217	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Gdia_0222	COG2072	flavoprotein involved in K transport
Gdia_0223	COG0583	DNA-binding transcription factor activity
Gdia_0225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Gdia_0230	COG1953	Uracil, thiamine, allantoin
Gdia_0231	COG2134	cdp-diacylglycerol pyrophosphatase
Gdia_0232	COG0248	Ppx GppA phosphatase
Gdia_0233	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Gdia_0235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Gdia_0236	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Gdia_0237	COG0105	UTP biosynthetic process
Gdia_0238	COG0488	(ABC) transporter
Gdia_0240	COG1289	transmembrane transporter activity
Gdia_0241	COG1566	PFAM secretion protein HlyD family protein
Gdia_0244	COG0628	permease
Gdia_0245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gdia_0252	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Gdia_0256	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Gdia_0260	COG0670	Belongs to the BI1 family
Gdia_0264	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Gdia_0266	COG2095	MarC family integral membrane protein
Gdia_0268	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Gdia_0269	COG1199	ATP-dependent helicase activity
Gdia_0270	COG1278	Cold shock
Gdia_0271	COG0459	protein refolding
Gdia_0272	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Gdia_0273	COG5425	PFAM Usg family protein
Gdia_0275	COG0412	Dienelactone hydrolase
Gdia_0276	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Gdia_0277	COG2857	Cytochrome c1
Gdia_0278	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Gdia_0279	COG0408	coproporphyrinogen oxidase activity
Gdia_0281	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Gdia_0282	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Gdia_0285	COG1858	cytochrome C peroxidase
Gdia_0286	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Gdia_0289	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Gdia_0291	COG0181	hydroxymethylbilane synthase activity
Gdia_0292	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Gdia_0293	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Gdia_0294	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Gdia_0296	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Gdia_0297	COG0386	Belongs to the glutathione peroxidase family
Gdia_0298	COG0728	peptidoglycan biosynthetic process
Gdia_0299	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Gdia_0300	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Gdia_0305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Gdia_0309	COG0612	Peptidase, M16
Gdia_0310	COG0312	modulator of DNA gyrase
Gdia_0319	COG0109	protoheme IX farnesyltransferase activity
Gdia_0322	COG0189	ligase activity
Gdia_0325	COG0556	nucleotide-excision repair
Gdia_0328	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Gdia_0337	COG1137	ATPase activity
Gdia_0338	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Gdia_0339	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Gdia_0344	COG1518	maintenance of DNA repeat elements
Gdia_0346	COG0242	peptide deformylase activity
Gdia_0347	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Gdia_0348	COG0101	tRNA pseudouridine synthase activity
Gdia_0350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gdia_0351	COG2171	N-acyltransferase activity
Gdia_0352	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Gdia_0353	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Gdia_0354	COG0706	membrane insertase activity
Gdia_0355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Gdia_0356	COG0594	ribonuclease P activity
Gdia_0357	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Gdia_0359	COG0346	lactoylglutathione lyase activity
Gdia_0360	COG3494	Protein of unknown function (DUF1009)
Gdia_0361	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Gdia_0362	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Gdia_0363	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Gdia_0365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Gdia_0366	COG0750	zinc metalloprotease
Gdia_0367	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Gdia_0368	COG0575	Belongs to the CDS family
Gdia_0369	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Gdia_0370	COG0233	cytoplasmic translational termination
Gdia_0371	COG0528	UMP kinase activity
Gdia_0373	COG0571	ribonuclease III activity
Gdia_0374	COG0681	Belongs to the peptidase S26 family
Gdia_0375	COG0736	holo-[acyl-carrier-protein] synthase activity
Gdia_0376	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Gdia_0377	COG1758	RNA polymerase activity
Gdia_0378	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Gdia_0381	COG0579	oxidoreductase
Gdia_0384	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Gdia_0387	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Gdia_0388	COG2814	Major facilitator Superfamily
Gdia_0389	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0390	COG4948	Mandelate Racemase Muconate Lactonizing
Gdia_0391	COG0800	Aldolase
Gdia_0392	COG3734	2-keto-3-deoxy-galactonokinase
Gdia_0393	COG1414	Transcriptional regulator
Gdia_0399	COG1546	Belongs to the CinA family
Gdia_0399	COG1058	Belongs to the CinA family
Gdia_0400	COG0825	malonyl-CoA metabolic process
Gdia_0401	COG4974	Belongs to the 'phage' integrase family
Gdia_0403	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Gdia_0404	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Gdia_0404	COG2885	chlorophyll binding
Gdia_0406	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Gdia_0407	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Gdia_0410	COG0667	Aldo Keto reductase
Gdia_0416	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Gdia_0417	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Gdia_0418	COG0534	Mate efflux family protein
Gdia_0419	COG0215	cysteine-tRNA ligase activity
Gdia_0420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Gdia_0421	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Gdia_0422	COG1518	maintenance of DNA repeat elements
Gdia_0425	COG1857	crispr-associated protein
Gdia_0428	COG1203	CRISPR-associated helicase, Cas3
Gdia_0429	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Gdia_0432	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Gdia_0437	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Gdia_0438	COG0805	protein transport
Gdia_0439	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Gdia_0440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Gdia_0441	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Gdia_0443	COG0018	arginyl-trna synthetase
Gdia_0444	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Gdia_0445	COG0316	Belongs to the HesB IscA family
Gdia_0446	COG0708	Exodeoxyribonuclease III
Gdia_0450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Gdia_0451	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Gdia_0452	COG0326	Molecular chaperone. Has ATPase activity
Gdia_0453	COG1051	belongs to the nudix hydrolase family
Gdia_0455	COG3161	chorismate lyase activity
Gdia_0456	COG2252	PERMEase
Gdia_0457	COG3706	GGDEF domain
Gdia_0473	COG0564	pseudouridine synthase activity
Gdia_0474	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Gdia_0475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Gdia_0476	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Gdia_0478	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Gdia_0479	COG3956	TIGRFAM MazG family protein
Gdia_0480	COG0483	inositol monophosphate 1-phosphatase activity
Gdia_0481	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Gdia_0482	COG1923	regulation of RNA biosynthetic process
Gdia_0483	COG2204	response regulator
Gdia_0488	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Gdia_0488	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Gdia_0492	COG0564	pseudouridine synthase activity
Gdia_0493	COG5001	Diguanylate cyclase
Gdia_0493	COG3300	MHYT domain
Gdia_0497	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Gdia_0499	COG2081	HI0933 family
Gdia_0501	COG0850	regulation of cytokinetic process
Gdia_0502	COG2894	cell division
Gdia_0503	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Gdia_0504	COG1802	Transcriptional regulator
Gdia_0505	COG1132	(ABC) transporter
Gdia_0506	COG0438	transferase activity, transferring glycosyl groups
Gdia_0508	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Gdia_0509	COG0438	transferase activity, transferring glycosyl groups
Gdia_0509	COG1216	Glycosyl transferase, family 2
Gdia_0511	COG1072	(Pantothenic acid kinase))
Gdia_0514	COG0405	Gamma-glutamyltransferase
Gdia_0516	COG0156	8-amino-7-oxononanoate synthase activity
Gdia_0520	COG0126	phosphoglycerate kinase activity
Gdia_0521	COG0552	protein localization to endoplasmic reticulum
Gdia_0522	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Gdia_0523	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Gdia_0524	COG0346	lactoylglutathione lyase activity
Gdia_0528	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Gdia_0532	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Gdia_0532	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Gdia_0533	COG0509	glycine decarboxylation via glycine cleavage system
Gdia_0534	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Gdia_0536	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Gdia_0537	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Gdia_0538	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Gdia_0539	COG0629	single-stranded DNA binding
Gdia_0540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Gdia_0541	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Gdia_0542	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Gdia_0570	COG3657	addiction module killer protein
Gdia_0575	COG3416	Protein conserved in bacteria
Gdia_0576	COG0752	glycyl-tRNA synthetase alpha subunit
Gdia_0579	COG0772	Belongs to the SEDS family
Gdia_0580	COG0768	penicillin binding
Gdia_0586	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Gdia_0588	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gdia_0589	COG1530	ribonuclease E activity
Gdia_0590	COG0840	transmembrane signaling receptor activity
Gdia_0596	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Gdia_0597	COG0347	Belongs to the P(II) protein family
Gdia_0598	COG0004	ammonium transporteR
Gdia_0602	COG4974	Belongs to the 'phage' integrase family
Gdia_0604	COG0753	catalase activity
Gdia_0605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Gdia_0607	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Gdia_0611	COG0523	cobalamin synthesis protein
Gdia_0612	COG0438	transferase activity, transferring glycosyl groups
Gdia_0614	COG0482	sulfurtransferase activity
Gdia_0616	COG1104	cysteine desulfurase activity
Gdia_0618	COG2945	thiolester hydrolase activity
Gdia_0619	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Gdia_0622	COG2309	aminopeptidase activity
Gdia_0624	COG0438	transferase activity, transferring glycosyl groups
Gdia_0626	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Gdia_0627	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Gdia_0627	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Gdia_0628	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Gdia_0629	COG3158	transport of potassium into the cell
Gdia_0630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gdia_0635	COG2814	Major facilitator Superfamily
Gdia_0637	COG0495	leucyl-tRNA aminoacylation
Gdia_0641	COG0156	8-amino-7-oxononanoate synthase activity
Gdia_0647	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Gdia_0656	COG3328	transposase activity
Gdia_0667	COG0346	lactoylglutathione lyase activity
Gdia_0671	COG1522	sequence-specific DNA binding
Gdia_0672	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Gdia_0673	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gdia_0679	COG1280	lysine exporter protein (LysE YggA)
Gdia_0682	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gdia_0689	COG1129	ABC transporter
Gdia_0690	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_0691	COG4213	ABC transporter substrate-binding protein
Gdia_0695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Gdia_0698	COG2224	Isocitrate lyase
Gdia_0699	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Gdia_0700	COG0390	transport system, permease component
Gdia_0701	COG4619	ABC transporter
Gdia_0704	COG1231	oxidoreductase activity
Gdia_0706	COG1007	ATP synthesis coupled electron transport
Gdia_0709	COG0713	ATP synthesis coupled electron transport
Gdia_0710	COG0839	Belongs to the complex I subunit 6 family
Gdia_0711	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_0712	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Gdia_0713	COG1034	ATP synthesis coupled electron transport
Gdia_0716	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_0716	COG0649	NAD binding
Gdia_0717	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_0718	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_0719	COG1473	amidohydrolase
Gdia_0721	COG2188	Transcriptional regulator
Gdia_0724	COG3511	phospholipase C
Gdia_0725	COG0251	oxidation-reduction process
Gdia_0728	COG0604	alcohol dehydrogenase
Gdia_0733	COG0438	transferase activity, transferring glycosyl groups
Gdia_0734	COG1596	polysaccharide export
Gdia_0737	COG0489	protein tyrosine kinase activity
Gdia_0738	COG0438	transferase activity, transferring glycosyl groups
Gdia_0748	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gdia_0757	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Gdia_0757	COG0546	phosphoglycolate phosphatase activity
Gdia_0758	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Gdia_0764	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gdia_0765	COG2235	arginine
Gdia_0768	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Gdia_0770	COG2814	Major facilitator Superfamily
Gdia_0771	COG2207	Transcriptional regulator
Gdia_0772	COG1064	alcohol dehydrogenase
Gdia_0774	COG4214	carbohydrate transport
Gdia_0776	COG4213	ABC transporter substrate-binding protein
Gdia_0777	COG2244	polysaccharide biosynthetic process
Gdia_0778	COG1216	Glycosyl transferase, family 2
Gdia_0784	COG1215	transferase activity, transferring glycosyl groups
Gdia_0785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Gdia_0791	COG1596	polysaccharide export
Gdia_0800	COG2226	methyltransferase
Gdia_0802	COG5001	Diguanylate cyclase
Gdia_0803	COG5001	Diguanylate cyclase
Gdia_0803	COG3300	MHYT domain
Gdia_0806	COG0531	amino acid
Gdia_0807	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Gdia_0812	COG1609	Transcriptional regulator
Gdia_0814	COG4651	solute:proton antiporter activity
Gdia_0814	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Gdia_0817	COG0339	signal peptide processing
Gdia_0820	COG1956	GAF domain-containing protein
Gdia_0821	COG5001	Diguanylate cyclase
Gdia_0827	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Gdia_0828	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Gdia_0835	COG0437	4 iron, 4 sulfur cluster binding
Gdia_0837	COG0840	transmembrane signaling receptor activity
Gdia_0839	COG1280	lysine exporter protein (LysE YggA)
Gdia_0840	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0841	COG1879	ABC-type sugar transport system periplasmic component
Gdia_0842	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_0845	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_0847	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Gdia_0851	COG3842	ATPase activity
Gdia_0852	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0855	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_0859	COG1116	anion transmembrane transporter activity
Gdia_0859	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Gdia_0861	COG0459	protein refolding
Gdia_0862	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Gdia_0864	COG0450	alkyl hydroperoxide reductase
Gdia_0867	COG1464	Belongs to the NlpA lipoprotein family
Gdia_0868	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Gdia_0869	COG2011	ABC-type metal ion transport system permease component
Gdia_0872	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_0873	COG1129	ABC transporter
Gdia_0874	COG1609	Transcriptional regulator
Gdia_0878	COG4948	Mandelate Racemase Muconate Lactonizing
Gdia_0879	COG0179	Fumarylacetoacetate (FAA) hydrolase
Gdia_0880	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0881	COG2186	Transcriptional regulator
Gdia_0883	COG0506	proline dehydrogenase activity
Gdia_0883	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Gdia_0883	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Gdia_0886	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0889	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0891	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0892	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_0900	COG2801	Transposase and inactivated derivatives
Gdia_0904	COG1744	ABC transporter substrate-binding protein PnrA-like
Gdia_0911	COG4821	SIS domain
Gdia_0912	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_0914	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Gdia_0915	COG4206	TonB-dependent receptor
Gdia_0916	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gdia_0917	COG1126	abc transporter atp-binding protein
Gdia_0921	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gdia_0922	COG1126	abc transporter atp-binding protein
Gdia_0923	COG0765	amino acid transport
Gdia_0925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Gdia_0928	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gdia_0929	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gdia_0931	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gdia_0941	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Gdia_0942	COG0640	Transcriptional regulator
Gdia_0944	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_0945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gdia_0946	COG0583	DNA-binding transcription factor activity
Gdia_0949	COG0583	DNA-binding transcription factor activity
Gdia_0956	COG0583	DNA-binding transcription factor activity
Gdia_0963	COG3451	type IV secretory pathway VirB4
Gdia_0965	COG3838	Conjugal transfer protein Trbc
Gdia_0966	COG4962	Type ii secretion system protein e
Gdia_0972	COG1794	racemase activity, acting on amino acids and derivatives
Gdia_0976	COG0741	lytic transglycosylase activity
Gdia_0977	COG5489	Protein of unknown function (DUF736)
Gdia_0985	COG1476	TRANSCRIPTIONal
Gdia_0986	COG5489	Protein of unknown function (DUF736)
Gdia_0992	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gdia_0993	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Gdia_0995	COG0300	oxidoreductase activity
Gdia_0996	COG1733	regulation of RNA biosynthetic process
Gdia_0997	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Gdia_0999	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_1001	COG1538	Outer membrane efflux protein
Gdia_1002	COG0583	DNA-binding transcription factor activity
Gdia_1010	COG3451	type IV secretory pathway VirB4
Gdia_1012	COG3838	Conjugal transfer protein Trbc
Gdia_1013	COG4962	Type ii secretion system protein e
Gdia_1019	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Gdia_1028	COG0741	lytic transglycosylase activity
Gdia_1033	COG1192	Involved in chromosome partitioning
Gdia_1041	COG5489	Protein of unknown function (DUF736)
Gdia_1048	COG1408	metallophosphoesterase
Gdia_1050	COG1309	transcriptional regulator
Gdia_1052	COG0583	DNA-binding transcription factor activity
Gdia_1053	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_1055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Gdia_1062	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Gdia_1065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Gdia_1072	COG3077	Addiction module antitoxin, RelB DinJ family
Gdia_1073	COG2026	Addiction module toxin, RelE StbE family
Gdia_1077	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gdia_1078	COG3608	succinylglutamate desuccinylase aspartoacylase
Gdia_1078	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Gdia_1079	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Gdia_1080	COG0251	oxidation-reduction process
Gdia_1082	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Gdia_1083	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Gdia_1084	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Gdia_1086	COG0193	aminoacyl-tRNA hydrolase activity
Gdia_1087	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Gdia_1088	COG0406	alpha-ribazole phosphatase activity
Gdia_1089	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Gdia_1093	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Gdia_1099	COG0776	regulation of translation
Gdia_1102	COG1216	Glycosyl transferase, family 2
Gdia_1104	COG5487	UPF0391 membrane protein
Gdia_1105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Gdia_1107	COG1877	trehalose-phosphatase activity
Gdia_1112	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Gdia_1117	COG0538	isocitrate dehydrogenase activity
Gdia_1119	COG0513	Belongs to the DEAD box helicase family
Gdia_1123	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Gdia_1130	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Gdia_1133	COG0246	Mannitol dehydrogenase
Gdia_1138	COG0489	protein tyrosine kinase activity
Gdia_1141	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Gdia_1142	COG0343	queuine tRNA-ribosyltransferase activity
Gdia_1143	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Gdia_1145	COG1881	PFAM PEBP family protein
Gdia_1147	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Gdia_1151	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Gdia_1152	COG0633	Ferredoxin
Gdia_1152	COG3217	Mosc domain protein beta barrel domain protein
Gdia_1157	COG0167	dihydroorotate dehydrogenase activity
Gdia_1166	COG0114	fumarate hydratase activity
Gdia_1169	COG0583	DNA-binding transcription factor activity
Gdia_1171	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Gdia_1172	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Gdia_1182	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Gdia_1182	COG0662	Cupin 2, conserved barrel domain protein
Gdia_1183	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Gdia_1185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Gdia_1195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gdia_1201	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_1202	COG0745	RESPONSE REGULATOR receiver
Gdia_1204	COG0352	thiamine-phosphate diphosphorylase activity
Gdia_1204	COG0351	phosphomethylpyrimidine kinase
Gdia_1205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Gdia_1208	COG0037	tRNA processing
Gdia_1210	COG2885	chlorophyll binding
Gdia_1211	COG0823	Involved in the tonB-independent uptake of proteins
Gdia_1215	COG0824	Thioesterase
Gdia_1216	COG2255	four-way junction helicase activity
Gdia_1217	COG0632	four-way junction helicase activity
Gdia_1218	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Gdia_1219	COG0217	transcriptional regulatory protein
Gdia_1220	COG0653	protein targeting
Gdia_1221	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Gdia_1222	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Gdia_1224	COG0668	transmembrane transport
Gdia_1226	COG1696	Membrane protein involved in D-alanine export
Gdia_1228	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Gdia_1229	COG1127	ABC transporter
Gdia_1230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Gdia_1230	COG3008	intermembrane lipid transfer
Gdia_1233	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Gdia_1237	COG2967	ApaG domain
Gdia_1238	COG0302	gtp cyclohydrolase
Gdia_1242	COG0450	alkyl hydroperoxide reductase
Gdia_1243	COG3634	alkyl hydroperoxide reductase activity
Gdia_1246	COG0521	Mo-molybdopterin cofactor biosynthetic process
Gdia_1248	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Gdia_1262	COG0415	Belongs to the DNA photolyase family
Gdia_1264	COG0484	heat shock protein binding
Gdia_1266	COG0247	lactate metabolic process
Gdia_1268	COG0277	FAD linked oxidase domain protein
Gdia_1269	COG0247	lactate metabolic process
Gdia_1270	COG1139	Iron-sulfur cluster binding protein
Gdia_1272	COG0667	Aldo Keto reductase
Gdia_1279	COG2205	protein histidine kinase activity
Gdia_1280	COG1238	metal cluster binding
Gdia_1283	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Gdia_1286	COG0741	lytic transglycosylase activity
Gdia_1287	COG1253	flavin adenine dinucleotide binding
Gdia_1288	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Gdia_1289	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Gdia_1293	COG3394	polysaccharide catabolic process
Gdia_1294	COG3118	belongs to the thioredoxin family
Gdia_1295	COG1074	ATP-dependent DNA helicase activity
Gdia_1296	COG2887	Belongs to the helicase family. UvrD subfamily
Gdia_1297	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Gdia_1299	COG0492	ferredoxin-NADP+ reductase activity
Gdia_1300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Gdia_1301	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gdia_1302	COG0347	Belongs to the P(II) protein family
Gdia_1303	COG0004	ammonium transporteR
Gdia_1307	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gdia_1310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Gdia_1311	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Gdia_1312	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Gdia_1313	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Gdia_1314	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Gdia_1315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Gdia_1316	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Gdia_1317	COG1609	Transcriptional regulator
Gdia_1318	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_1323	COG3008	intermembrane lipid transfer
Gdia_1324	COG2995	paraquat-inducible protein a
Gdia_1325	COG2814	Major facilitator Superfamily
Gdia_1327	COG1802	Transcriptional regulator
Gdia_1328	COG2271	Major facilitator Superfamily
Gdia_1329	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Gdia_1330	COG1250	3-hydroxyacyl-CoA dehydrogenase
Gdia_1330	COG1024	Enoyl-CoA hydratase
Gdia_1332	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Gdia_1334	COG4221	oxidoreductase activity
Gdia_1337	COG0438	transferase activity, transferring glycosyl groups
Gdia_1339	COG4206	TonB-dependent receptor
Gdia_1341	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Gdia_1342	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Gdia_1344	COG2824	Alkylphosphonate utilization operon protein PhnA
Gdia_1349	COG1942	4-Oxalocrotonate Tautomerase
Gdia_1350	COG0778	Nitroreductase
Gdia_1351	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Gdia_1352	COG1914	H( )-stimulated, divalent metal cation uptake system
Gdia_1353	COG1321	iron dependent repressor
Gdia_1356	COG0672	)-iron permease
Gdia_1361	COG0730	response to heat
Gdia_1362	COG2814	Major facilitator Superfamily
Gdia_1366	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_1370	COG3685	Protein conserved in bacteria
Gdia_1372	COG3158	transport of potassium into the cell
Gdia_1373	COG0438	transferase activity, transferring glycosyl groups
Gdia_1377	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Gdia_1378	COG1260	myo-inositol-1-phosphate synthase
Gdia_1380	COG1929	Belongs to the glycerate kinase type-1 family
Gdia_1381	COG2271	Major facilitator Superfamily
Gdia_1385	COG1522	sequence-specific DNA binding
Gdia_1388	COG1522	sequence-specific DNA binding
Gdia_1390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Gdia_1393	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Gdia_1394	COG2814	Major facilitator Superfamily
Gdia_1396	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Gdia_1400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gdia_1403	COG5564	TIM-barrel signal transduction protein
Gdia_1405	COG0778	Nitroreductase
Gdia_1408	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Gdia_1410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Gdia_1411	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Gdia_1412	COG0196	riboflavin kinase activity
Gdia_1413	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Gdia_1414	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Gdia_1415	COG0235	Class ii aldolase
Gdia_1416	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Gdia_1419	COG2226	methyltransferase
Gdia_1421	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Gdia_1423	COG0450	alkyl hydroperoxide reductase
Gdia_1424	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Gdia_1426	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Gdia_1428	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Gdia_1437	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gdia_1439	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_1447	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Gdia_1448	COG4208	sulfate ABC transporter
Gdia_1450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Gdia_1457	COG1671	Belongs to the UPF0178 family
Gdia_1458	COG2986	histidine ammonia-lyase
Gdia_1461	COG1640	4-alpha-glucanotransferase
Gdia_1462	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Gdia_1465	COG0297	glycogen (starch) synthase activity
Gdia_1472	COG1271	oxidase subunit
Gdia_1473	COG1294	oxidase, subunit
Gdia_1475	COG2814	Major facilitator Superfamily
Gdia_1476	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Gdia_1477	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Gdia_1483	COG0038	chloride channel
Gdia_1484	COG0604	alcohol dehydrogenase
Gdia_1484	COG3321	synthase
Gdia_1484	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_1485	COG2267	carboxylic ester hydrolase activity
Gdia_1488	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Gdia_1489	COG1607	acyl-coa hydrolase
Gdia_1490	COG1692	metallophosphoesterase
Gdia_1491	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Gdia_1495	COG0352	thiamine-phosphate diphosphorylase activity
Gdia_1499	COG1509	lysine 2,3-aminomutase activity
Gdia_1500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Gdia_1501	COG0483	inositol monophosphate 1-phosphatase activity
Gdia_1506	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Gdia_1512	COG0438	transferase activity, transferring glycosyl groups
Gdia_1513	COG1959	2 iron, 2 sulfur cluster binding
Gdia_1515	COG3189	MarR family transcriptional regulator
Gdia_1516	COG3588	fructose-bisphosphate aldolase
Gdia_1518	COG1450	Type ii and iii secretion system protein
Gdia_1523	COG2165	general secretion pathway protein
Gdia_1526	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Gdia_1530	COG1621	beta-fructofuranosidase activity
Gdia_1536	COG2169	Transcriptional regulator
Gdia_1536	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Gdia_1539	COG0753	catalase activity
Gdia_1541	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gdia_1542	COG0601	transmembrane transport
Gdia_1543	COG0747	negative chemotaxis
Gdia_1544	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gdia_1545	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_1546	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gdia_1549	COG0667	Aldo Keto reductase
Gdia_1550	COG0840	transmembrane signaling receptor activity
Gdia_1553	COG0644	oxidoreductase
Gdia_1554	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gdia_1555	COG2086	electron transfer activity
Gdia_1558	COG1104	cysteine desulfurase activity
Gdia_1560	COG0316	Belongs to the HesB IscA family
Gdia_1563	COG5420	small protein containing a coiled-coil domain
Gdia_1565	COG1433	Dinitrogenase iron-molybdenum cofactor
Gdia_1566	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Gdia_1567	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Gdia_1568	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Gdia_1569	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Gdia_1570	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Gdia_1572	COG5554	nitrogen fixation
Gdia_1573	COG5554	nitrogen fixation
Gdia_1575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gdia_1576	COG0535	radical SAM domain protein
Gdia_1577	COG3604	Transcriptional regulator
Gdia_1581	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Gdia_1581	COG1618	nucleotide phosphatase activity, acting on free nucleotides
Gdia_1582	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Gdia_1583	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Gdia_1584	COG1522	sequence-specific DNA binding
Gdia_1585	COG0473	3-isopropylmalate dehydrogenase activity
Gdia_1587	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_1589	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gdia_1591	COG2837	iron assimilation
Gdia_1618	COG0778	Nitroreductase
Gdia_1619	COG0131	Imidazoleglycerol-phosphate dehydratase
Gdia_1621	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Gdia_1622	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Gdia_1623	COG0107	imidazoleglycerol-phosphate synthase activity
Gdia_1624	COG0140	phosphoribosyl-ATP diphosphatase activity
Gdia_1633	COG1518	maintenance of DNA repeat elements
Gdia_1637	COG5265	(ABC) transporter
Gdia_1638	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Gdia_1640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Gdia_1641	COG0540	Belongs to the ATCase OTCase family
Gdia_1642	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gdia_1643	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Gdia_1644	COG0758	DNA mediated transformation
Gdia_1645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Gdia_1646	COG0557	exoribonuclease II activity
Gdia_1647	COG0793	Belongs to the peptidase S41A family
Gdia_1649	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Gdia_1649	COG2885	chlorophyll binding
Gdia_1650	COG0583	DNA-binding transcription factor activity
Gdia_1652	COG1289	transmembrane transporter activity
Gdia_1653	COG2814	Major facilitator Superfamily
Gdia_1656	COG1492	cobalamin metabolic process
Gdia_1661	COG3547	Transposase (IS116 IS110 IS902 family)
Gdia_1670	COG1846	Transcriptional regulator
Gdia_1671	COG1764	response to oxidative stress
Gdia_1674	COG1309	transcriptional regulator
Gdia_1675	COG0604	alcohol dehydrogenase
Gdia_1678	COG2801	Transposase and inactivated derivatives
Gdia_1683	COG0667	Aldo Keto reductase
Gdia_1684	COG0583	DNA-binding transcription factor activity
Gdia_1689	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_1690	COG0625	glutathione transferase activity
Gdia_1691	COG0625	glutathione transferase activity
Gdia_1693	COG1595	DNA-templated transcription, initiation
Gdia_1694	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_1695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_1696	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Gdia_1697	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Gdia_1699	COG0778	Nitroreductase
Gdia_1707	COG2186	Transcriptional regulator
Gdia_1708	COG0625	glutathione transferase activity
Gdia_1711	COG2249	NAD(P)H dehydrogenase (quinone) activity
Gdia_1714	COG2814	Major facilitator Superfamily
Gdia_1715	COG0640	Transcriptional regulator
Gdia_1718	COG2814	Major facilitator Superfamily
Gdia_1724	COG2801	Transposase and inactivated derivatives
Gdia_1735	COG3609	addiction module antidote protein, CC2985 family
Gdia_1750	COG2801	Transposase and inactivated derivatives
Gdia_1754	COG0071	Belongs to the small heat shock protein (HSP20) family
Gdia_1757	COG3077	Addiction module antitoxin, RelB DinJ family
Gdia_1758	COG2026	Addiction module toxin, RelE StbE family
Gdia_1762	COG0542	response to heat
Gdia_1764	COG0667	Aldo Keto reductase
Gdia_1769	COG1431	PFAM Stem cell self-renewal protein Piwi
Gdia_1772	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Gdia_1773	COG2814	Major facilitator Superfamily
Gdia_1775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Gdia_1777	COG3830	Belongs to the UPF0237 family
Gdia_1777	COG0560	Phosphoserine phosphatase
Gdia_1778	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Gdia_1779	COG0028	Belongs to the TPP enzyme family
Gdia_1781	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Gdia_1788	COG0489	protein tyrosine kinase activity
Gdia_1801	COG2983	Belongs to the UPF0260 family
Gdia_1804	COG3842	ATPase activity
Gdia_1808	COG1289	transmembrane transporter activity
Gdia_1810	COG1566	PFAM secretion protein HlyD family protein
Gdia_1811	COG1538	Outer membrane efflux protein
Gdia_1815	COG0438	transferase activity, transferring glycosyl groups
Gdia_1815	COG1216	Glycosyl transferase, family 2
Gdia_1822	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Gdia_1823	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Gdia_1825	COG1657	PFAM Prenyltransferase squalene oxidase
Gdia_1826	COG1233	COG1233 Phytoene dehydrogenase and related
Gdia_1827	COG1562	ergosterol biosynthetic process
Gdia_1828	COG1562	ergosterol biosynthetic process
Gdia_1830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gdia_1832	COG0287	Prephenate dehydrogenase
Gdia_1833	COG0281	malic enzyme
Gdia_1836	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Gdia_1842	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gdia_1843	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Gdia_1844	COG0300	oxidoreductase activity
Gdia_1845	COG0194	GDP metabolic process
Gdia_1846	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Gdia_1846	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Gdia_1847	COG2942	2-epimerase
Gdia_1848	COG0305	Participates in initiation and elongation during chromosome replication
Gdia_1851	COG1127	ABC transporter
Gdia_1852	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Gdia_1853	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Gdia_1854	COG2814	Major facilitator Superfamily
Gdia_1857	COG0243	molybdopterin cofactor binding
Gdia_1858	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Gdia_1864	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Gdia_1865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Gdia_1865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Gdia_1866	COG0307	riboflavin synthase, alpha
Gdia_1869	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Gdia_1870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Gdia_1879	COG1597	lipid kinase activity
Gdia_1882	COG5001	Diguanylate cyclase
Gdia_1882	COG3300	MHYT domain
Gdia_1887	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Gdia_1888	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Gdia_1890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Gdia_1891	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Gdia_1892	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Gdia_1893	COG0356	it plays a direct role in the translocation of protons across the membrane
Gdia_1896	COG0138	bifunctional purine biosynthesis protein purh
Gdia_1899	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Gdia_1900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gdia_1901	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gdia_1901	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gdia_1902	COG1660	Displays ATPase and GTPase activities
Gdia_1905	COG1131	(ABC) transporter
Gdia_1907	COG4585	Histidine kinase
Gdia_1908	COG2197	response regulator
Gdia_1909	COG5328	Belongs to the UPF0262 family
Gdia_1910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gdia_1912	COG0477	Major facilitator Superfamily
Gdia_1913	COG0673	inositol 2-dehydrogenase activity
Gdia_1915	COG1063	alcohol dehydrogenase
Gdia_1922	COG3214	Protein conserved in bacteria
Gdia_1923	COG2135	peptidase activity
Gdia_1926	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gdia_1927	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Gdia_1928	COG0424	maF-like protein
Gdia_1930	COG4181	ATPase activity
Gdia_1936	COG1475	DNA binding
Gdia_1937	COG1192	Involved in chromosome partitioning
Gdia_1938	COG0357	Ribosomal RNA small subunit methyltransferase G
Gdia_1939	COG0445	tRNA wobble uridine modification
Gdia_1940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Gdia_1944	COG0586	Pfam SNARE associated Golgi protein
Gdia_1946	COG4566	intracellular signal transduction
Gdia_1947	COG4191	Histidine kinase
Gdia_1948	COG4774	siderophore transport
Gdia_1949	COG3128	pkhd-type hydroxylase
Gdia_1951	COG0183	Belongs to the thiolase family
Gdia_1952	COG2814	Major facilitator Superfamily
Gdia_1953	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Gdia_1954	COG1024	Enoyl-CoA hydratase
Gdia_1956	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Gdia_1959	COG0735	belongs to the Fur family
Gdia_1963	COG0285	dihydrofolate synthase activity
Gdia_1964	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Gdia_1965	COG0159	tryptophan synthase activity
Gdia_1966	COG0133	tryptophan synthase activity
Gdia_1968	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Gdia_1969	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Gdia_1970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Gdia_1971	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Gdia_1972	COG0484	heat shock protein binding
Gdia_1973	COG0443	Heat shock 70 kDa protein
Gdia_1974	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Gdia_1975	COG0745	RESPONSE REGULATOR receiver
Gdia_1976	COG2205	protein histidine kinase activity
Gdia_1978	COG0535	radical SAM domain protein
Gdia_1980	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Gdia_1981	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Gdia_1984	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gdia_1985	COG3047	cAMP biosynthetic process
Gdia_1986	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gdia_1994	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_1996	COG1538	Outer membrane efflux protein
Gdia_1997	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_1999	COG0469	pyruvate kinase activity
Gdia_2002	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Gdia_2006	COG0564	pseudouridine synthase activity
Gdia_2007	COG1674	ftsk spoiiie
Gdia_2008	COG0742	ribosomal rna small subunit methyltransferase
Gdia_2009	COG1187	pseudouridine synthase activity
Gdia_2010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Gdia_2012	COG0037	tRNA processing
Gdia_2012	COG0590	tRNA wobble adenosine to inosine editing
Gdia_2013	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Gdia_2015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Gdia_2026	COG0574	Belongs to the PEP-utilizing enzyme family
Gdia_2026	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Gdia_2027	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Gdia_2030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Gdia_2035	COG0135	phosphoribosylanthranilate isomerase activity
Gdia_2036	COG0284	orotidine-5'-phosphate decarboxylase activity
Gdia_2040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Gdia_2041	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Gdia_2043	COG0312	modulator of DNA gyrase
Gdia_2044	COG4774	siderophore transport
Gdia_2047	COG1612	heme a metabolic process
Gdia_2049	COG2814	Major facilitator Superfamily
Gdia_2050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Gdia_2051	COG1289	transmembrane transporter activity
Gdia_2052	COG0439	Biotin carboxylase
Gdia_2053	COG0511	ligase activity, forming carbon-carbon bonds
Gdia_2058	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Gdia_2059	COG4133	protoheme IX ABC transporter activity
Gdia_2061	COG1126	abc transporter atp-binding protein
Gdia_2062	COG0765	amino acid transport
Gdia_2063	COG0583	DNA-binding transcription factor activity
Gdia_2065	COG0542	response to heat
Gdia_2067	COG0779	Required for maturation of 30S ribosomal subunits
Gdia_2070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Gdia_2070	COG5373	membrane
Gdia_2071	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Gdia_2073	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Gdia_2074	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Gdia_2075	COG1185	polyribonucleotide nucleotidyltransferase activity
Gdia_2081	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Gdia_2082	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Gdia_2083	COG1420	regulation of RNA biosynthetic process
Gdia_2084	COG0667	Aldo Keto reductase
Gdia_2093	COG2205	protein histidine kinase activity
Gdia_2096	COG0778	Nitroreductase
Gdia_2100	COG4957	zinc ion binding
Gdia_2103	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Gdia_2104	COG1396	sequence-specific DNA binding
Gdia_2106	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Gdia_2110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Gdia_2111	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Gdia_2116	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Gdia_2117	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Gdia_2119	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gdia_2120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Gdia_2126	COG0598	Magnesium transport protein CorA
Gdia_2128	COG2233	PERMEase
Gdia_2130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Gdia_2132	COG0071	Belongs to the small heat shock protein (HSP20) family
Gdia_2136	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Gdia_2138	COG0424	maF-like protein
Gdia_2139	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Gdia_2140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Gdia_2141	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Gdia_2142	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Gdia_2143	COG0717	Belongs to the dCTP deaminase family
Gdia_2146	COG0297	glycogen (starch) synthase activity
Gdia_2148	COG0859	PFAM glycosyl transferase family 9
Gdia_2149	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Gdia_2150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Gdia_2156	COG2205	protein histidine kinase activity
Gdia_2157	COG0745	RESPONSE REGULATOR receiver
Gdia_2159	COG1643	Atp-dependent helicase
Gdia_2162	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Gdia_2164	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Gdia_2165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Gdia_2170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gdia_2171	COG0488	(ABC) transporter
Gdia_2172	COG5006	permease, DMT superfamily
Gdia_2173	COG0187	DNA topoisomerase II activity
Gdia_2176	COG1959	2 iron, 2 sulfur cluster binding
Gdia_2179	COG3038	cytochrome b561
Gdia_2180	COG2353	YceI-like domain
Gdia_2181	COG0655	NAD(P)H dehydrogenase (quinone) activity
Gdia_2182	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Gdia_2186	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2186	COG3347	Dehydrogenase
Gdia_2187	COG1070	Carbohydrate kinase
Gdia_2190	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_2191	COG1129	ABC transporter
Gdia_2194	COG1760	l-serine dehydratase
Gdia_2196	COG0457	Tetratricopeptide repeat
Gdia_2202	COG0517	IMP dehydrogenase activity
Gdia_2204	COG2132	Multicopper oxidase
Gdia_2206	COG2814	Major facilitator Superfamily
Gdia_2208	COG0745	RESPONSE REGULATOR receiver
Gdia_2212	COG0481	GTPase activity
Gdia_2218	COG0693	protein deglycase activity
Gdia_2219	COG2271	Major facilitator Superfamily
Gdia_2220	COG1063	alcohol dehydrogenase
Gdia_2222	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_2226	COG1309	transcriptional regulator
Gdia_2229	COG0604	alcohol dehydrogenase
Gdia_2232	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Gdia_2233	COG2199	diguanylate cyclase activity
Gdia_2235	COG1648	precorrin-2 dehydrogenase activity
Gdia_2235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Gdia_2236	COG1763	Mo-molybdopterin cofactor biosynthetic process
Gdia_2237	COG0746	molybdenum cofactor guanylyltransferase activity
Gdia_2238	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Gdia_2240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Gdia_2242	COG3961	Belongs to the TPP enzyme family
Gdia_2245	COG2308	Evidence 4 Homologs of previously reported genes of
Gdia_2251	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Gdia_2252	COG2835	tetraacyldisaccharide 4'-kinase activity
Gdia_2253	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Gdia_2254	COG3118	belongs to the thioredoxin family
Gdia_2255	COG1733	regulation of RNA biosynthetic process
Gdia_2256	COG0604	alcohol dehydrogenase
Gdia_2258	COG4336	lyase activity
Gdia_2262	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Gdia_2263	COG0583	DNA-binding transcription factor activity
Gdia_2265	COG0154	amidase activity
Gdia_2271	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gdia_2272	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Gdia_2273	COG1984	allophanate hydrolase subunit 2
Gdia_2274	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Gdia_2275	COG2271	Major facilitator Superfamily
Gdia_2277	COG0583	DNA-binding transcription factor activity
Gdia_2279	COG2843	Capsule synthesis protein
Gdia_2280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gdia_2284	COG0583	DNA-binding transcription factor activity
Gdia_2286	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Gdia_2289	COG0583	DNA-binding transcription factor activity
Gdia_2290	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2293	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Gdia_2298	COG1309	transcriptional regulator
Gdia_2299	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2300	COG1902	pentaerythritol trinitrate reductase activity
Gdia_2307	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Gdia_2312	COG0601	transmembrane transport
Gdia_2320	COG0784	Response regulator, receiver
Gdia_2320	COG4191	Histidine kinase
Gdia_2325	COG1063	alcohol dehydrogenase
Gdia_2326	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2328	COG2376	Dihydroxyacetone kinase
Gdia_2329	COG1461	Dihydroxyacetone kinase
Gdia_2330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gdia_2330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Gdia_2331	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Gdia_2332	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Gdia_2336	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gdia_2340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gdia_2341	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Gdia_2343	COG0025	NhaP-type Na H and K H
Gdia_2345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Gdia_2349	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Gdia_2350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Gdia_2351	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Gdia_2352	COG0561	phosphatase activity
Gdia_2354	COG0363	glucosamine-6-phosphate deaminase activity
Gdia_2355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Gdia_2356	COG3265	gluconokinase activity
Gdia_2360	COG2199	diguanylate cyclase activity
Gdia_2360	COG2200	EAL domain
Gdia_2360	COG2202	Pas domain
Gdia_2369	COG4303	Ethanolamine ammonia lyase large subunit
Gdia_2370	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_2371	COG1252	NADH dehydrogenase
Gdia_2373	COG0330	HflC and HflK could
Gdia_2377	COG1024	Enoyl-CoA hydratase
Gdia_2382	COG4993	Dehydrogenase
Gdia_2384	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Gdia_2396	COG1902	pentaerythritol trinitrate reductase activity
Gdia_2397	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Gdia_2398	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Gdia_2399	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Gdia_2400	COG1012	belongs to the aldehyde dehydrogenase family
Gdia_2401	COG0477	Major facilitator Superfamily
Gdia_2403	COG1335	isochorismatase
Gdia_2404	COG0477	Major facilitator Superfamily
Gdia_2405	COG1609	Transcriptional regulator
Gdia_2407	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2411	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_2413	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gdia_2414	COG3962	Belongs to the TPP enzyme family
Gdia_2415	COG3718	enzyme involved in inositol metabolism
Gdia_2417	COG0673	inositol 2-dehydrogenase activity
Gdia_2426	COG2801	Transposase and inactivated derivatives
Gdia_2433	COG3328	transposase activity
Gdia_2472	COG3728	DNA packaging
Gdia_2472	COG5484	DNA packaging
Gdia_2475	COG1061	Type III restriction enzyme res subunit
Gdia_2503	COG1494	fructose-1,6-bisphosphatase
Gdia_2505	COG0436	Aminotransferase
Gdia_2507	COG0740	serine-type endopeptidase activity
Gdia_2516	COG1953	Uracil, thiamine, allantoin
Gdia_2517	COG0583	DNA-binding transcription factor activity
Gdia_2518	COG0402	S-adenosylhomocysteine deaminase activity
Gdia_2522	COG0517	IMP dehydrogenase activity
Gdia_2525	COG5001	Diguanylate cyclase
Gdia_2530	COG2837	iron assimilation
Gdia_2534	COG1393	Belongs to the ArsC family
Gdia_2538	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gdia_2547	COG5001	Diguanylate cyclase
Gdia_2547	COG3300	MHYT domain
Gdia_2582	COG0513	Belongs to the DEAD box helicase family
Gdia_2585	COG1408	metallophosphoesterase
Gdia_2591	COG4774	siderophore transport
Gdia_2592	COG4206	TonB-dependent receptor
Gdia_2598	COG0577	efflux transmembrane transporter activity
Gdia_2599	COG0577	efflux transmembrane transporter activity
Gdia_2600	COG1136	(ABC) transporter
Gdia_2600	COG0577	efflux transmembrane transporter activity
Gdia_2602	COG2204	response regulator
Gdia_2603	COG4191	Histidine kinase
Gdia_2604	COG1129	ABC transporter
Gdia_2606	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gdia_2608	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Gdia_2609	COG0673	inositol 2-dehydrogenase activity
Gdia_2611	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2612	COG1609	Transcriptional regulator
Gdia_2617	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gdia_2622	COG2144	transferase activity, transferring acyl groups
Gdia_2625	COG2072	flavoprotein involved in K transport
Gdia_2633	COG0584	glycerophosphoryl diester phosphodiesterase
Gdia_2636	COG1289	transmembrane transporter activity
Gdia_2637	COG1566	PFAM secretion protein HlyD family protein
Gdia_2638	COG1538	Outer membrane efflux protein
Gdia_2639	COG0038	chloride channel
Gdia_2645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Gdia_2648	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Gdia_2649	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Gdia_2650	COG1733	regulation of RNA biosynthetic process
Gdia_2660	COG0583	DNA-binding transcription factor activity
Gdia_2662	COG1113	amino acid transport
Gdia_2663	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Gdia_2666	COG0668	transmembrane transport
Gdia_2669	COG1309	transcriptional regulator
Gdia_2670	COG1538	Outer membrane efflux protein
Gdia_2671	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Gdia_2675	COG1598	PFAM Uncharacterised protein family UPF0150
Gdia_2681	COG1278	Cold shock
Gdia_2683	COG2199	diguanylate cyclase activity
Gdia_2683	COG2199	diguanylate cyclase activity
Gdia_2683	COG2200	EAL domain
Gdia_2683	COG2202	Pas domain
Gdia_2683	COG2200	EAL domain
Gdia_2683	COG2202	Pas domain
Gdia_2684	COG0573	inorganic phosphate transmembrane transporter activity
Gdia_2685	COG0581	inorganic phosphate transmembrane transporter activity
Gdia_2686	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Gdia_2687	COG0704	Plays a role in the regulation of phosphate uptake
Gdia_2688	COG0745	RESPONSE REGULATOR receiver
Gdia_2690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Gdia_2692	COG0306	phosphate transporter
Gdia_2696	COG1126	abc transporter atp-binding protein
Gdia_2699	COG0640	Transcriptional regulator
Gdia_2700	COG0450	alkyl hydroperoxide reductase
Gdia_2708	COG0842	Transport permease protein
Gdia_2708	COG1129	ABC transporter
Gdia_2714	COG1301	dicarboxylic acid transport
Gdia_2715	COG0129	dihydroxy-acid dehydratase activity
Gdia_2717	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_2719	COG0583	DNA-binding transcription factor activity
Gdia_2720	COG0625	glutathione transferase activity
Gdia_2723	COG1192	Involved in chromosome partitioning
Gdia_2742	COG2801	Transposase and inactivated derivatives
Gdia_2743	COG3316	Transposase and inactivated derivatives
Gdia_2748	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_2749	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_2751	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Gdia_2754	COG0154	amidase activity
Gdia_2757	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Gdia_2770	COG4974	Belongs to the 'phage' integrase family
Gdia_2772	COG1196	nuclear chromosome segregation
Gdia_2791	COG5489	Protein of unknown function (DUF736)
Gdia_2792	COG1476	TRANSCRIPTIONal
Gdia_2799	COG1192	Involved in chromosome partitioning
Gdia_2802	COG4959	Type IV secretory pathway protease TraF
Gdia_2809	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Gdia_2812	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2820	COG2367	Beta-lactamase
Gdia_2824	COG4962	Type ii secretion system protein e
Gdia_2827	COG3451	type IV secretory pathway VirB4
Gdia_2831	COG3701	Conjugal transfer protein
Gdia_2839	COG0673	inositol 2-dehydrogenase activity
Gdia_2840	COG1309	transcriptional regulator
Gdia_2842	COG2267	carboxylic ester hydrolase activity
Gdia_2843	COG1309	transcriptional regulator
Gdia_2846	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gdia_2846	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gdia_2847	COG1999	signal sequence binding
Gdia_2848	COG0747	negative chemotaxis
Gdia_2852	COG4608	Belongs to the ABC transporter superfamily
Gdia_2855	COG1215	transferase activity, transferring glycosyl groups
Gdia_2859	COG4221	oxidoreductase activity
Gdia_2864	COG1570	exodeoxyribonuclease VII activity
Gdia_2872	COG1285	pathogenesis
Gdia_2876	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Gdia_2877	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_2878	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Gdia_2879	COG1286	toxin biosynthetic process
Gdia_2881	COG1410	methionine synthase
Gdia_2881	COG0646	methionine synthase
Gdia_2883	COG2274	protein secretion by the type I secretion system
Gdia_2888	COG0438	transferase activity, transferring glycosyl groups
Gdia_2889	COG1742	UPF0060 membrane protein
Gdia_2890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Gdia_2891	COG0488	(ABC) transporter
Gdia_2894	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gdia_2895	COG1678	Uncharacterized ACR, COG1678
Gdia_2896	COG4221	oxidoreductase activity
Gdia_2897	COG2326	polyphosphate kinase activity
Gdia_2899	COG0583	DNA-binding transcription factor activity
Gdia_2904	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Gdia_2905	COG1686	Belongs to the peptidase S11 family
Gdia_2906	COG0024	Methionine aminopeptidase
Gdia_2908	COG2816	NAD+ diphosphatase activity
Gdia_2910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Gdia_2911	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Gdia_2912	COG0300	oxidoreductase activity
Gdia_2913	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Gdia_2915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Gdia_2916	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Gdia_2917	COG0539	negative regulation of cytoplasmic translation
Gdia_2919	COG4771	TonB-dependent receptor
Gdia_2920	COG2271	Major facilitator Superfamily
Gdia_2921	COG0667	Aldo Keto reductase
Gdia_2922	COG0612	Peptidase, M16
Gdia_2930	COG3088	subunit of a heme lyase
Gdia_2931	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gdia_2932	COG1138	Cytochrome C-type biogenesis protein
Gdia_2933	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Gdia_2935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Gdia_2946	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Gdia_2949	COG1322	Protein conserved in bacteria
Gdia_2951	COG0642	Histidine kinase
Gdia_2954	COG1538	Outer membrane efflux protein
Gdia_2956	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Gdia_2957	COG0081	regulation of translation
Gdia_2958	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Gdia_2959	COG0222	ribosome binding
Gdia_2960	COG0085	RNA polymerase activity
Gdia_2961	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Gdia_2962	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Gdia_2963	COG0049	tRNA binding
Gdia_2964	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Gdia_2965	COG0051	transcription antitermination factor activity, RNA binding
Gdia_2966	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Gdia_2967	COG0088	Forms part of the polypeptide exit tunnel
Gdia_2968	COG0089	rRNA binding
Gdia_2969	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Gdia_2970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Gdia_2971	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Gdia_2972	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Gdia_2973	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Gdia_2974	COG0255	Belongs to the universal ribosomal protein uL29 family
Gdia_2975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Gdia_2976	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Gdia_2977	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Gdia_2978	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Gdia_2979	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Gdia_2980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Gdia_2981	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Gdia_2982	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Gdia_2983	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Gdia_2984	COG1841	ribosomal large subunit assembly
Gdia_2985	COG0200	Binds to the 23S rRNA
Gdia_2986	COG0201	protein transport
Gdia_2987	COG0563	adenylate kinase activity
Gdia_2988	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Gdia_2989	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Gdia_2990	COG0202	RNA polymerase activity
Gdia_2991	COG0203	ribosomal protein L17
Gdia_2994	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Gdia_2995	COG1091	dTDP-4-dehydrorhamnose reductase activity
Gdia_2999	COG0438	transferase activity, transferring glycosyl groups
Gdia_2999	COG1216	Glycosyl transferase, family 2
Gdia_3004	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gdia_3005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gdia_3007	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Gdia_3008	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Gdia_3013	COG0714	Associated with various cellular activities
Gdia_3016	COG1132	(ABC) transporter
Gdia_3017	COG1566	PFAM secretion protein HlyD family protein
Gdia_3018	COG2814	Major facilitator Superfamily
Gdia_3020	COG1051	belongs to the nudix hydrolase family
Gdia_3021	COG0793	Belongs to the peptidase S41A family
Gdia_3023	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Gdia_3024	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_3025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Gdia_3026	COG3360	Dodecin
Gdia_3027	COG1487	ribonuclease activity
Gdia_3028	COG4691	Plasmid stability protein
Gdia_3029	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Gdia_3030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Gdia_3031	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Gdia_3032	COG0505	Belongs to the CarA family
Gdia_3033	COG1610	YqeY-like protein
Gdia_3034	COG0358	DNA primase activity
Gdia_3036	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Gdia_3038	COG0360	Binds together with S18 to 16S ribosomal RNA
Gdia_3039	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Gdia_3040	COG0359	binds to the 23S rRNA
Gdia_3041	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Gdia_3042	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Gdia_3043	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Gdia_3047	COG0277	FAD linked oxidase domain protein
Gdia_3049	COG0009	L-threonylcarbamoyladenylate synthase
Gdia_3050	COG1218	3'(2'),5'-bisphosphate nucleotidase
Gdia_3051	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Gdia_3054	COG0656	L-ascorbic acid biosynthetic process
Gdia_3059	COG0649	NAD binding
Gdia_3060	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_3062	COG0688	phosphatidylethanolamine metabolic process
Gdia_3063	COG2226	methyltransferase
Gdia_3064	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gdia_3065	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_3067	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Gdia_3072	COG2884	Cell division ATP-binding protein ftsE
Gdia_3078	COG2198	Histidine kinase
Gdia_3078	COG0643	Histidine kinase
Gdia_3082	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Gdia_3083	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Gdia_3088	COG2010	Cytochrome c
Gdia_3088	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Gdia_3089	COG4993	Dehydrogenase
Gdia_3090	COG0246	Mannitol dehydrogenase
Gdia_3091	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Gdia_3092	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Gdia_3093	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Gdia_3094	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Gdia_3094	COG0072	phenylalanine-tRNA ligase activity
Gdia_3095	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Gdia_3098	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Gdia_3102	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gdia_3105	COG4993	Dehydrogenase
Gdia_3105	COG2010	Cytochrome c
Gdia_3106	COG1160	GTP binding
Gdia_3108	COG2814	Major facilitator Superfamily
Gdia_3109	COG0412	Dienelactone hydrolase
Gdia_3110	COG2814	Major facilitator Superfamily
Gdia_3112	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Gdia_3116	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Gdia_3117	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Gdia_3121	COG1663	tetraacyldisaccharide 4'-kinase activity
Gdia_3122	COG1519	Transferase
Gdia_3124	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Gdia_3128	COG0175	sulfate reduction
Gdia_3130	COG0259	pyridoxamine-phosphate oxidase activity
Gdia_3131	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Gdia_3132	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Gdia_3133	COG1764	response to oxidative stress
Gdia_3134	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Gdia_3135	COG2813	Specifically methylates the guanine in position
Gdia_3135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Gdia_3136	COG2971	BadF BadG BcrA BcrD
Gdia_3137	COG0513	Belongs to the DEAD box helicase family
Gdia_3140	COG2814	Major facilitator Superfamily
Gdia_3142	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Gdia_3143	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Gdia_3144	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Gdia_3152	COG1744	ABC transporter substrate-binding protein PnrA-like
Gdia_3153	COG1335	isochorismatase
Gdia_3159	COG1253	flavin adenine dinucleotide binding
Gdia_3160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Gdia_3162	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Gdia_3164	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Gdia_3166	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Gdia_3167	COG1181	Belongs to the D-alanine--D-alanine ligase family
Gdia_3168	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Gdia_3169	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Gdia_3170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Gdia_3172	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Gdia_3173	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Gdia_3174	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Gdia_3175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Gdia_3178	COG0275	rRNA processing
Gdia_3179	COG2001	Belongs to the MraZ family
Gdia_3181	COG0723	plastoquinol--plastocyanin reductase activity
Gdia_3183	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Gdia_3184	COG3750	Belongs to the UPF0335 family
Gdia_3186	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Gdia_3187	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Gdia_3188	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Gdia_3189	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Gdia_3192	COG0402	S-adenosylhomocysteine deaminase activity
Gdia_3193	COG1289	transmembrane transporter activity
Gdia_3194	COG1573	uracil-dna glycosylase
Gdia_3195	COG0625	glutathione transferase activity
Gdia_3196	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gdia_3197	COG4957	zinc ion binding
Gdia_3198	COG0616	signal peptide processing
Gdia_3199	COG0776	regulation of translation
Gdia_3202	COG0583	DNA-binding transcription factor activity
Gdia_3203	COG0492	ferredoxin-NADP+ reductase activity
Gdia_3204	COG1522	sequence-specific DNA binding
Gdia_3211	COG0519	Catalyzes the synthesis of GMP from XMP
Gdia_3211	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Gdia_3220	COG1136	(ABC) transporter
Gdia_3226	COG3547	Transposase (IS116 IS110 IS902 family)
Gdia_3228	COG1879	ABC-type sugar transport system periplasmic component
Gdia_3230	COG1063	alcohol dehydrogenase
Gdia_3236	COG1393	Belongs to the ArsC family
Gdia_3237	COG2608	mercury ion transmembrane transporter activity
Gdia_3238	COG2217	Heavy metal translocating P-type atpase
Gdia_3239	COG1032	radical SAM domain protein
Gdia_3242	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Gdia_3249	COG2271	Major facilitator Superfamily
Gdia_3252	COG3265	gluconokinase activity
Gdia_3253	COG2096	Adenosyltransferase
Gdia_3257	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Gdia_3262	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Gdia_3263	COG1297	OPT oligopeptide transporter protein
Gdia_3265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Gdia_3266	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Gdia_3267	COG0328	RNA-DNA hybrid ribonuclease activity
Gdia_3268	COG1116	anion transmembrane transporter activity
Gdia_3269	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gdia_3270	COG0573	inorganic phosphate transmembrane transporter activity
Gdia_3271	COG0581	inorganic phosphate transmembrane transporter activity
Gdia_3272	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Gdia_3273	COG0704	Plays a role in the regulation of phosphate uptake
Gdia_3276	COG0228	four-way junction DNA binding
Gdia_3277	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Gdia_3278	COG0336	Belongs to the RNA methyltransferase TrmD family
Gdia_3279	COG0335	large ribosomal subunit rRNA binding
Gdia_3280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Gdia_3281	COG0066	3-isopropylmalate dehydratase activity
Gdia_3282	COG0473	3-isopropylmalate dehydrogenase activity
Gdia_3283	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Gdia_3284	COG0242	peptide deformylase activity
Gdia_3286	COG1846	Transcriptional regulator
Gdia_3287	COG0745	RESPONSE REGULATOR receiver
Gdia_3288	COG2205	protein histidine kinase activity
Gdia_3291	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Gdia_3292	COG0416	fatty acid biosynthetic process
Gdia_3293	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gdia_3294	COG0776	regulation of translation
Gdia_3296	COG0628	permease
Gdia_3300	COG5265	(ABC) transporter
Gdia_3302	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Gdia_3303	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Gdia_3307	COG2733	membrane
Gdia_3309	COG0719	Fe-S assembly protein
Gdia_3310	COG0396	ATPase activity
Gdia_3311	COG0719	Fe-S assembly protein
Gdia_3312	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Gdia_3314	COG2151	metal-sulfur cluster biosynthetic enzyme
Gdia_3318	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Gdia_3319	COG0513	Belongs to the DEAD box helicase family
Gdia_3320	COG3387	PFAM Glycoside hydrolase 15-related
Gdia_3322	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Gdia_3322	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Gdia_3323	COG0544	peptidyl-prolyl cis-trans isomerase activity
Gdia_3324	COG0740	serine-type endopeptidase activity
Gdia_3325	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Gdia_3327	COG0776	regulation of translation
Gdia_3328	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_3329	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_3330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_3331	COG0649	NAD binding
Gdia_3332	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Gdia_3334	COG1034	ATP synthesis coupled electron transport
Gdia_3335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Gdia_3336	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Gdia_3340	COG1007	ATP synthesis coupled electron transport
Gdia_3343	COG0442	prolyl-tRNA aminoacylation
Gdia_3345	COG1136	(ABC) transporter
Gdia_3346	COG0587	DNA-directed DNA polymerase activity
Gdia_3347	COG0052	Belongs to the universal ribosomal protein uS2 family
Gdia_3348	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Gdia_3349	COG1381	Involved in DNA repair and RecF pathway recombination
Gdia_3350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Gdia_3351	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Gdia_3352	COG0113	porphobilinogen synthase activity
Gdia_3353	COG0531	amino acid
Gdia_3354	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Gdia_3358	COG0513	Belongs to the DEAD box helicase family
Gdia_3370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Gdia_3371	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Gdia_3372	COG0154	amidase activity
Gdia_3373	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Gdia_3376	COG0295	cytidine deaminase activity
Gdia_3377	COG0019	diaminopimelate decarboxylase activity
Gdia_3379	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Gdia_3381	COG0165	Argininosuccinate lyase
Gdia_3382	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gdia_3384	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Gdia_3385	COG0237	dephospho-CoA kinase activity
Gdia_3386	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Gdia_3392	COG0659	secondary active sulfate transmembrane transporter activity
Gdia_3394	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Gdia_3395	COG0602	queuosine metabolic process
Gdia_3396	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Gdia_3398	COG0045	succinate-CoA ligase (ADP-forming) activity
Gdia_3401	COG3590	peptidase
Gdia_3407	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Gdia_3408	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Gdia_3409	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Gdia_3411	COG0483	inositol monophosphate 1-phosphatase activity
Gdia_3421	COG0156	8-amino-7-oxononanoate synthase activity
Gdia_3423	COG0318	PFAM AMP-dependent synthetase and ligase
Gdia_3428	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Gdia_3432	COG1706	bacterial-type flagellum-dependent cell motility
Gdia_3437	COG1815	bacterial-type flagellum-dependent cell motility
Gdia_3438	COG1558	bacterial-type flagellum-dependent cell motility
Gdia_3439	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Gdia_3440	COG1677	Flagellar hook-basal body complex protein FliE
Gdia_3441	COG1987	bacterial-type flagellum assembly
Gdia_3443	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Gdia_3444	COG1749	Flagellar hook protein flgE
Gdia_3445	COG0840	transmembrane signaling receptor activity
Gdia_3447	COG0745	RESPONSE REGULATOR receiver
Gdia_3450	COG1157	protein secretion by the type III secretion system
Gdia_3454	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Gdia_3458	COG1766	The M ring may be actively involved in energy transduction
Gdia_3459	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Gdia_3461	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Gdia_3462	COG3190	flagellar
Gdia_3463	COG1338	Plays a role in the flagellum-specific transport system
Gdia_3464	COG0840	transmembrane signaling receptor activity
Gdia_3467	COG0643	Histidine kinase
Gdia_3467	COG2198	Histidine kinase
Gdia_3468	COG0835	chemotaxis
Gdia_3469	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Gdia_3470	COG2201	protein-glutamate methylesterase activity
Gdia_3471	COG0745	RESPONSE REGULATOR receiver
Gdia_3472	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Gdia_3474	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Gdia_3476	COG4786	Flagellar basal body rod
Gdia_3477	COG4786	Flagellar basal body rod
Gdia_3487	COG4964	Belongs to the GSP D family
Gdia_3502	COG0022	dehydrogenase e1 component
Gdia_3503	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gdia_3505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Gdia_3510	COG0071	Belongs to the small heat shock protein (HSP20) family
Gdia_3511	COG0254	rRNA binding
Gdia_3512	COG1970	mechanosensitive ion channel activity
Gdia_3514	COG1028	Short-chain dehydrogenase reductase Sdr
Gdia_3518	COG0673	inositol 2-dehydrogenase activity
Gdia_3521	COG0784	Response regulator, receiver
Gdia_3526	COG4988	ABC transporter
Gdia_3527	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Gdia_3529	COG0514	ATP-dependent DNA helicase (RecQ)
Gdia_3533	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Gdia_3535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Gdia_3536	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Gdia_3537	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Gdia_3540	COG0837	glucose binding
Gdia_3541	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Gdia_3543	COG0525	valine-tRNA ligase activity
Gdia_3544	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gdia_3545	COG1116	anion transmembrane transporter activity
Gdia_3547	COG0756	dUTP diphosphatase activity
Gdia_3548	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Gdia_3549	COG2226	methyltransferase
Gdia_3550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Gdia_3551	COG0268	Binds directly to 16S ribosomal RNA
Gdia_3557	COG3654	unkown
Gdia_3569	COG1487	ribonuclease activity
Gdia_3570	COG4691	Plasmid stability protein
Gdia_3575	COG1487	ribonuclease activity