locus-tag	class	description
FXF46_00040	ENOG4105GZI	Transcriptional regulator
FXF46_00050	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FXF46_00055	ENOG4105D07	Signal peptide peptidase, SppA
FXF46_00065	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FXF46_00070	ENOG4105DSW	Fusaric acid resistance protein
FXF46_00095	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FXF46_00100	ENOG4105K46	50S ribosomal protein l27
FXF46_00105	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FXF46_00110	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FXF46_00120	ENOG4105Y2X	UPF0335 protein
FXF46_00125	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FXF46_00145	ENOG4107YUR	Cell division protein mraZ
FXF46_00150	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FXF46_00165	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FXF46_00170	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FXF46_00175	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FXF46_00180	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FXF46_00190	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FXF46_00195	ENOG4105DFU	Cell wall formation (By similarity)
FXF46_00200	ENOG4105D4A	Cell wall formation (By similarity)
FXF46_00205	ENOG4105CPF	Cell wall formation (By similarity)
FXF46_00210	ENOG4108UFP	Essential cell division protein (By similarity)
FXF46_00215	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FXF46_00225	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FXF46_00230	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FXF46_00235	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FXF46_00240	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FXF46_00245	ENOG4105C37	(CBS) domain
FXF46_00250	ENOG4108RWI	nicotinamidase
FXF46_00275	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FXF46_00290	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FXF46_00295	ENOG4105CUV	Homoserine Kinase
FXF46_00300	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FXF46_00315	ENOG4105EPD	Oligopeptide transporter, Opt family
FXF46_00325	ENOG4108WBT	adenosyltransferase
FXF46_00355	ENOG4105CHM	Aminotransferase
FXF46_00360	ENOG4105CHM	Aminotransferase
FXF46_00365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FXF46_00370	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FXF46_00375	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FXF46_00380	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FXF46_00385	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FXF46_00390	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FXF46_00395	ENOG4105K5M	30s ribosomal protein S16
FXF46_00400	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FXF46_00425	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
FXF46_00430	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
FXF46_00485	ENOG4108W0P	ABC transporter
FXF46_00490	ENOG4105EHG	Permease protein
FXF46_00505	ENOG4105C1J	atp-dependent rna helicase
FXF46_00515	ENOG4105DWV	Homoserine O-trans-acetylase
FXF46_00520	ENOG4105DWV	Homoserine O-trans-acetylase
FXF46_00535	ENOG4105E0K	tonB-dependent siderophore receptor
FXF46_00545	ENOG4105BZU	Histidine kinase
FXF46_00550	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
FXF46_00595	ENOG4105XEA	Tetr family transcriptional regulator
FXF46_00600	ENOG4107RRE	RNA-directed DNA polymerase
FXF46_00610	ENOG4105KVH	Transcriptional regulator
FXF46_00620	ENOG4107NQ8	LysR family Transcriptional regulator
FXF46_00625	ENOG4105ETT	transcriptional Regulator, LysR family
FXF46_00645	ENOG4105D3W	isochorismatase
FXF46_00650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FXF46_00660	ENOG4105FA0	parb-like partition protein
FXF46_00715	ENOG4105D48	metallophosphoesterase
FXF46_00720	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FXF46_00745	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FXF46_00775	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FXF46_00780	ENOG4105ECY	inositol monophosphatase
FXF46_00800	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FXF46_00820	ENOG4105C7N	Xanthine uracil vitamin C permease
FXF46_00840	ENOG4105VFE	sira family
FXF46_00845	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FXF46_00850	ENOG4105CTB	Polyprenyl synthetase
FXF46_00855	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FXF46_00860	ENOG4105DX0	Hemolysin A
FXF46_00865	ENOG4105J7D	transcriptional regulator
FXF46_00875	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FXF46_00880	ENOG4105CDH	Citrulline--aspartate ligase
FXF46_00885	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FXF46_00905	ENOG4105C31	Tryptophanyl-tRNA synthetase
FXF46_00910	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FXF46_00915	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FXF46_00920	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FXF46_00925	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FXF46_00930	ENOG41082BR	50S ribosomal protein L35
FXF46_00935	ENOG4105DZG	Dehydrogenase
FXF46_00950	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FXF46_00955	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FXF46_00960	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FXF46_00985	ENOG4105CAK	Cell division ATP-binding protein ftsE
FXF46_01010	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FXF46_01015	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FXF46_01025	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FXF46_01035	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FXF46_01040	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FXF46_01045	ENOG4105DKQ	ROK family
FXF46_01050	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_01055	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_01080	ENOG4105CV8	reductase
FXF46_01090	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FXF46_01105	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FXF46_01125	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FXF46_01130	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FXF46_01135	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FXF46_01140	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FXF46_01145	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FXF46_01150	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FXF46_01155	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FXF46_01160	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FXF46_01170	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FXF46_01175	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FXF46_01185	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FXF46_01190	ENOG4105W8H	transhydrogenase (subunit alpha
FXF46_01195	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FXF46_01215	ENOG4105C8Q	Methyl-accepting chemotaxis
FXF46_01225	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FXF46_01230	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FXF46_01235	ENOG4105VMP	Transcriptional regulator
FXF46_01245	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FXF46_01250	ENOG4105C7B	Threonine dehydratase
FXF46_01265	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FXF46_01270	ENOG4105E0X	reductase
FXF46_01280	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FXF46_01290	ENOG4105CN1	protease
FXF46_01300	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FXF46_01305	ENOG4105BZ1	(ABC) transporter
FXF46_01310	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FXF46_01320	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FXF46_01345	ENOG4108J2P	Alpha beta hydrolase fold
FXF46_01355	ENOG4105CEC	DNA methylase N-4 N-6
FXF46_01360	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FXF46_01380	ENOG4105BZS	acriflavin resistance protein
FXF46_01390	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_01405	ENOG4105IE8	Alpha-ketoglutarate permease
FXF46_01410	ENOG4108ZT0	50S ribosomal protein l17
FXF46_01415	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FXF46_01420	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FXF46_01425	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FXF46_01430	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FXF46_01440	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FXF46_01445	ENOG4105VPB	50S ribosomal protein L30
FXF46_01450	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FXF46_01455	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FXF46_01460	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FXF46_01465	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FXF46_01470	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FXF46_01475	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FXF46_01480	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FXF46_01485	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FXF46_01490	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FXF46_01500	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FXF46_01505	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FXF46_01510	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FXF46_01515	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FXF46_01520	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FXF46_01525	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FXF46_01530	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FXF46_01535	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FXF46_01540	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FXF46_01545	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FXF46_01550	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FXF46_01555	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FXF46_01560	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FXF46_01565	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FXF46_01570	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FXF46_01575	ENOG4108VZM	50s ribosomal protein L10
FXF46_01580	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FXF46_01585	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FXF46_01590	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_01610	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FXF46_01625	ENOG4105CBX	hi0933 family
FXF46_01635	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FXF46_01640	ENOG4107QMS	site-determining protein
FXF46_01645	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FXF46_01660	ENOG4105D05	Receptor
FXF46_01665	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FXF46_01680	ENOG4105C8T	Leucyl-tRNA synthetase
FXF46_01685	ENOG4105TXM	Domain of unknown function (DUF3576)
FXF46_01700	ENOG4107TT2	Auxin Efflux Carrier
FXF46_01705	ENOG4105KJF	protein tyrosine phosphatase
FXF46_01710	ENOG4105C5I	Dehydrogenase
FXF46_01715	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FXF46_01730	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FXF46_01735	ENOG4105D7B	Flagellar biosynthesis protein flha
FXF46_01740	ENOG4105DD5	Flagellar motor switch protein
FXF46_01750	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FXF46_01755	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FXF46_01775	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FXF46_01815	ENOG4108JJA	ABC, transporter
FXF46_01825	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FXF46_01830	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FXF46_01835	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FXF46_01845	ENOG4107U9T	Pfam:Ribonuclease_BN
FXF46_01850	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FXF46_01855	ENOG4105X1Q	TOBE domain protein
FXF46_01885	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FXF46_01895	ENOG4107XAN	XdhC and CoxI family
FXF46_01905	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FXF46_01915	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FXF46_01920	ENOG4108UJD	30S ribosomal protein S9
FXF46_01925	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FXF46_01940	ENOG4105DFI	Membrane
FXF46_01955	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FXF46_01960	ENOG4105CHH	sulfate transporter
FXF46_01980	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FXF46_01985	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FXF46_01990	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FXF46_02015	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
FXF46_02020	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FXF46_02030	ENOG4105EGS	Mechanosensitive ion channel
FXF46_02045	ENOG4105CIS	alcohol dehydrogenase
FXF46_02050	ENOG4105MSY	salicylate hydroxylase
FXF46_02055	ENOG41069NU	Nitroreductase
FXF46_02060	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FXF46_02070	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FXF46_02075	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FXF46_02080	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FXF46_02085	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
FXF46_02090	ENOG4105K59	histidine triad (HIT) protein
FXF46_02110	ENOG4105MN3	Resolvase
FXF46_02145	ENOG4108C33	Resolvase
FXF46_02175	ENOG4108ESX	Receptor
FXF46_02180	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FXF46_02185	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_02190	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_02195	ENOG4105GKE	subunit e
FXF46_02200	ENOG4107QIZ	NADH dehydrogenase
FXF46_02205	ENOG4108IEH	NADH dehydrogenase subunit g
FXF46_02210	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FXF46_02215	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_02220	ENOG4107UFS	subunit j
FXF46_02230	ENOG4105D65	subunit l
FXF46_02235	ENOG4105C8S	subunit m
FXF46_02240	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_02260	ENOG4105EWU	Squalene--hopene cyclase
FXF46_02275	ENOG4106NZI	LysR family Transcriptional regulator
FXF46_02280	ENOG4105E0K	tonB-dependent siderophore receptor
FXF46_02300	ENOG4107R4J	Chloride channel
FXF46_02340	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FXF46_02350	ENOG4105C26	Dehydrogenase
FXF46_02360	ENOG4105CJP	fad dependent oxidoreductase
FXF46_02375	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FXF46_02405	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FXF46_02415	ENOG4108RYR	transcriptional regulator AsnC family
FXF46_02420	ENOG4105C26	Dehydrogenase
FXF46_02430	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FXF46_02505	ENOG4107TRE	AP endonuclease, family 2
FXF46_02510	ENOG4107QNK	)-transporter
FXF46_02515	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FXF46_02520	ENOG4107UEK	pfkb domain protein
FXF46_02530	ENOG4105CNN	ABC, transporter
FXF46_02540	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FXF46_02570	ENOG4108UAU	isochorismatase
FXF46_02580	ENOG4105C2W	permease
FXF46_02585	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
FXF46_02590	ENOG4108XHQ	(2Fe-2S)-binding domain protein
FXF46_02595	ENOG4105MSY	salicylate hydroxylase
FXF46_02600	ENOG4108VHT	MarR family transcriptional regulator
FXF46_02615	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FXF46_02630	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
FXF46_02635	ENOG4105VGJ	Virulence-associated protein
FXF46_02655	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FXF46_02660	ENOG4105CDA	abc transporter atp-binding protein
FXF46_02670	ENOG4105E5Q	amino acid AbC transporter
FXF46_02680	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FXF46_02685	ENOG4105CDA	abc transporter atp-binding protein
FXF46_02690	ENOG4105E5Q	amino acid AbC transporter
FXF46_02695	ENOG4105E5Q	amino acid AbC transporter
FXF46_02715	ENOG4107VFR	oxidoreductase
FXF46_02765	ENOG4105EEQ	Na H antiporter
FXF46_02810	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FXF46_02815	ENOG4105CPC	Aldo Keto reductase
FXF46_02825	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FXF46_02830	ENOG4105E9S	glutaredoxin 2
FXF46_02835	ENOG4108UJU	UPF0301 protein
FXF46_02840	ENOG4105EMU	Dehydrogenase
FXF46_02845	ENOG4105CSR	polyphosphate kinase 2
FXF46_02850	ENOG4105C1J	atp-dependent rna helicase
FXF46_02860	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FXF46_02865	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FXF46_02870	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FXF46_02885	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FXF46_02890	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
FXF46_02905	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FXF46_02910	ENOG4105DXN	mazG family
FXF46_02930	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FXF46_02935	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FXF46_02945	ENOG4105KT7	mgtC SapB transporter
FXF46_02955	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FXF46_02965	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FXF46_02980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FXF46_02985	ENOG4105DEI	Mannitol dehydrogenase
FXF46_02995	ENOG4105C0H	protease
FXF46_03000	ENOG4105D1F	ATP-binding protein
FXF46_03015	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
FXF46_03030	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FXF46_03085	ENOG4105DUX	Transporter
FXF46_03090	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FXF46_03100	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_03105	ENOG4105Y49	secretion protein, HlyD family
FXF46_03140	ENOG4108ZZ3	UPF0260 protein
FXF46_03205	ENOG4105MN3	Resolvase
FXF46_03220	ENOG4108C33	Resolvase
FXF46_03250	ENOG4105CPU	Monooxygenase
FXF46_03255	ENOG4105GVF	(ABC) transporter
FXF46_03260	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FXF46_03270	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FXF46_03275	ENOG4105CD3	dihydroorotase
FXF46_03290	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FXF46_03295	ENOG4107SJI	Dehydrogenase
FXF46_03300	ENOG4105BZ8	glutamate synthase
FXF46_03305	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FXF46_03310	ENOG41090VV	Protein of unknown function (DUF2846)
FXF46_03335	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FXF46_03340	ENOG4105YVS	arsR family transcriptional regulator
FXF46_03360	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FXF46_03380	ENOG4105VZ8	Transcriptional regulator
FXF46_03385	ENOG4105BZA	Phosphoglycerate kinase
FXF46_03410	ENOG4105M0C	cytoplasmic protein
FXF46_03415	ENOG4105C85	amino acid
FXF46_03420	ENOG4108XM1	transcriptional regulator AsnC family
FXF46_03440	ENOG4105DZG	Dehydrogenase
FXF46_03450	ENOG4105KUZ	arsenate reductase
FXF46_03455	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
FXF46_03460	ENOG4106N3A	copper homeostasis protein cutc
FXF46_03475	ENOG4105JQN	Transcriptional regulator
FXF46_03480	ENOG4105CSH	Transporter
FXF46_03490	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
FXF46_03495	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FXF46_03520	ENOG4108KB2	LysR family Transcriptional regulator
FXF46_03525	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FXF46_03530	ENOG4108I0Z	Aconitate hydratase
FXF46_03545	ENOG4105N14	lysine exporter protein LysE YggA
FXF46_03550	ENOG4108JU3	Alkyl hydroperoxide reductase
FXF46_03555	ENOG4105D3R	alkyl hydroperoxide reductase
FXF46_03560	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FXF46_03565	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
FXF46_03570	ENOG4105C5Q	Transcriptional regulator
FXF46_03585	ENOG4105EEQ	Na H antiporter
FXF46_03605	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FXF46_03615	ENOG4105C3J	Cysteine desulfurase
FXF46_03620	ENOG4105C3J	Cysteine desulfurase
FXF46_03625	ENOG4105DHZ	alpha beta
FXF46_03630	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FXF46_03655	ENOG4105D05	Receptor
FXF46_03665	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FXF46_03675	ENOG4105BZU	Histidine kinase
FXF46_03690	ENOG4108PQP	glycosyl transferase group 1
FXF46_03700	ENOG4105DJV	ribulose-phosphate 3-epimerase
FXF46_03745	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FXF46_03755	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_03760	ENOG4105BZS	acriflavin resistance protein
FXF46_03765	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FXF46_03805	ENOG4105C85	amino acid
FXF46_03810	ENOG4105BZU	Histidine kinase
FXF46_03815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FXF46_03820	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FXF46_03825	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FXF46_03830	ENOG4105E2Z	phosphate ABC transporter (Permease
FXF46_03835	ENOG4105C8U	phosphate abc transporter
FXF46_03845	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
FXF46_03870	ENOG4105K64	Glycosyl transferase, family 2
FXF46_03890	ENOG4105CNG	UPF0061 protein
FXF46_03905	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FXF46_03915	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FXF46_03920	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FXF46_03925	ENOG4105DJ9	glucan biosynthesis protein
FXF46_03930	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
FXF46_03935	ENOG4105KVH	Transcriptional regulator
FXF46_03940	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
FXF46_03970	ENOG4105Y49	secretion protein, HlyD family
FXF46_04010	ENOG4105C25	Primosomal protein n'
FXF46_04015	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FXF46_04030	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FXF46_04045	ENOG4105BZU	Histidine kinase
FXF46_04050	ENOG4108YZA	Nitrogen regulatory protein pii
FXF46_04060	ENOG4105D0A	hydroxylase
FXF46_04065	ENOG4105D7W	serine acetyltransferase
FXF46_04075	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FXF46_04100	ENOG4105C5H	ABC transporter
FXF46_04110	ENOG4105DSW	Fusaric acid resistance protein
FXF46_04120	ENOG4105F0N	pyrophosphate phospho-hydrolase
FXF46_04150	ENOG4105K63	Thioredoxin
FXF46_04160	ENOG4105W49	UPF0434 protein
FXF46_04165	ENOG4105UT3	Methyl-accepting chemotaxis
FXF46_04180	ENOG4108WRK	Transcriptional regulator
FXF46_04185	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FXF46_04195	ENOG41090R7	Ferric uptake
FXF46_04220	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
FXF46_04230	ENOG4105E0F	Histidine kinase
FXF46_04235	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FXF46_04240	ENOG4105D2N	Aldolase
FXF46_04255	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FXF46_04260	ENOG4105CW7	secretion protein, HlyD family
FXF46_04265	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FXF46_04275	ENOG4107W75	Flagellin
FXF46_04295	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FXF46_04310	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FXF46_04320	ENOG4105C0H	protease
FXF46_04325	ENOG4108Z6B	deaminase
FXF46_04330	ENOG4108Z86	Glutamine amidotransferase
FXF46_04335	ENOG4105FE9	pseudouridine synthase
FXF46_04340	ENOG4106H78	methyltransferase
FXF46_04345	ENOG4105CNU	cell division protein FtsK
FXF46_04370	ENOG4107QNK	)-transporter
FXF46_04385	ENOG4105MYN	Zinc uptake regulation protein
FXF46_04395	ENOG41080Z8	PHOSPHOCARRIER protein
FXF46_04400	ENOG4108YTN	IIa component
FXF46_04405	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FXF46_04410	ENOG4107UZ6	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
FXF46_04425	ENOG4105EB3	Histidine kinase
FXF46_04430	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FXF46_04435	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FXF46_04440	ENOG4105XA0	heptosyltransferase ii
FXF46_04450	ENOG4105C22	threonyL-tRNA synthetase
FXF46_04455	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FXF46_04465	ENOG4105C26	Dehydrogenase
FXF46_04490	ENOG4105EB3	Histidine kinase
FXF46_04495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FXF46_04505	ENOG4108VBZ	doxx family
FXF46_04515	ENOG4105CQ7	ATP-dependent helicase
FXF46_04520	ENOG4108DBC	nitroreductase
FXF46_04525	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FXF46_04535	ENOG4105C2C	drug resistance transporter, Bcr CflA
FXF46_04545	ENOG4105NTW	Transcriptional regulator
FXF46_04565	ENOG4107SFH	ImpB mucB samB family
FXF46_04575	ENOG4105F9N	Major Facilitator Superfamily
FXF46_04580	ENOG4108URH	decarboxylase
FXF46_04595	ENOG4105DEI	Mannitol dehydrogenase
FXF46_04610	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FXF46_04615	ENOG4105DHP	deoxycytidine triphosphate deaminase
FXF46_04650	ENOG4105CFG	Acts as a chaperone (By similarity)
FXF46_04655	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FXF46_04665	ENOG4105DMF	Dehydrogenase
FXF46_04670	ENOG4105CVJ	phosphoglycerate mutase
FXF46_04675	ENOG4105WYW	fructose-bisphosphate aldolase
FXF46_04685	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FXF46_04690	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FXF46_04695	ENOG4105KVH	Transcriptional regulator
FXF46_04700	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FXF46_04710	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FXF46_04715	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FXF46_04720	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FXF46_04725	ENOG4105BZJ	Electron transfer flavoprotein
FXF46_04730	ENOG4105C10	Electron transfer flavoprotein
FXF46_04735	ENOG4105C3F	Signal peptidase i
FXF46_04755	ENOG4105EDQ	levansucrase EC 2.4.1.10
FXF46_04770	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FXF46_04785	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FXF46_04790	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FXF46_04795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FXF46_04815	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FXF46_04825	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
FXF46_04840	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FXF46_04845	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FXF46_04850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FXF46_04855	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FXF46_04865	ENOG4108HF7	Gcn5-related n-acetyltransferase
FXF46_04875	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FXF46_04890	ENOG4105C72	UPF0176 protein
FXF46_04900	ENOG4107QUY	Guanine deaminase
FXF46_04905	ENOG4105C2W	permease
FXF46_04910	ENOG41084YZ	Hydrolase
FXF46_04925	ENOG4105E1J	oxidoreductase
FXF46_04930	ENOG4107653	Transcriptional regulator
FXF46_04950	ENOG4105KVH	Transcriptional regulator
FXF46_04955	ENOG4105D8X	mechanosensitive ion channel
FXF46_04980	ENOG4105C2C	drug resistance transporter, Bcr CflA
FXF46_04985	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FXF46_05005	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FXF46_05010	ENOG4107QNK	)-transporter
FXF46_05030	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FXF46_05035	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
FXF46_05040	ENOG4105E51	psp operon transcriptional activator
FXF46_05045	ENOG41087YS	Phage shock protein A
FXF46_05070	ENOG4105DHJ	ABC, transporter
FXF46_05125	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
FXF46_05130	ENOG4105DU0	nucleoside hydrolase
FXF46_05145	ENOG4105DTD	Dehydrogenase
FXF46_05150	ENOG4105BZS	acriflavin resistance protein
FXF46_05160	ENOG4105CGA	flagellar basal-body rod protein FlgG
FXF46_05165	ENOG4105CGA	flagellar basal-body rod protein FlgG
FXF46_05185	ENOG4105EV9	Alpha Beta Hydrolase
FXF46_05215	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FXF46_05220	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FXF46_05235	ENOG4105BZU	Histidine kinase
FXF46_05255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_05275	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FXF46_05285	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FXF46_05295	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FXF46_05300	ENOG4108R6K	riboflavin synthase, subunit alpha
FXF46_05310	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FXF46_05330	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
FXF46_05335	ENOG4105Z85	coenzyme PQQ synthesis
FXF46_05340	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
FXF46_05345	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
FXF46_05360	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FXF46_05370	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FXF46_05375	ENOG4105CC0	LysR family Transcriptional regulator
FXF46_05380	ENOG4107QJR	hflk protein
FXF46_05390	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FXF46_05395	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FXF46_05400	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FXF46_05405	ENOG4108Z03	MAF-like protein
FXF46_05415	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FXF46_05430	ENOG4108HKT	sucrose-6-phosphate hydrolase
FXF46_05435	ENOG4105DHU	Bile acid
FXF46_05475	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FXF46_05480	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FXF46_05495	ENOG4105BZE	flagellar hook protein, FlgE
FXF46_05505	ENOG4105CPC	Aldo Keto reductase
FXF46_05525	ENOG4105CHR	reductase
FXF46_05530	ENOG4105CMR	udp-glucose 4-epimerase
FXF46_05540	ENOG4108YXA	Membrane
FXF46_05545	ENOG4107YBY	Hydrolase
FXF46_05550	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FXF46_05555	ENOG4108UHJ	MAF-like protein
FXF46_05590	ENOG4105DIK	(ABC) transporter
FXF46_05605	ENOG4107QNK	)-transporter
FXF46_05635	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FXF46_05725	ENOG4105FA0	parb-like partition protein
FXF46_05730	ENOG4107QJE	Chromosome Partitioning Protein
FXF46_05735	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
FXF46_05740	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FXF46_05745	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FXF46_05750	ENOG4107TJ9	Cytochrome
FXF46_05755	ENOG4105DZG	Dehydrogenase
FXF46_05760	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FXF46_05780	ENOG4105C7S	Dehydrogenase
FXF46_05795	ENOG4105D6F	Phosphatase
FXF46_05805	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FXF46_05850	ENOG4105CEN	a g-specific adenine glycosylase
FXF46_05865	ENOG4105EAC	phosphoserine phosphatase
FXF46_05870	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FXF46_05875	ENOG4105C7K	acetolactate synthase
FXF46_05880	ENOG4108ZP8	Acetolactate synthase small subunit
FXF46_05885	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FXF46_05895	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
FXF46_05900	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
FXF46_05920	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FXF46_05925	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FXF46_05930	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FXF46_05950	ENOG4107RF4	Phosphodiesterase
FXF46_05955	ENOG4105EN6	Membrane
FXF46_05960	ENOG4105C5F	glutamine synthetase
FXF46_05970	ENOG4105CHM	Aminotransferase
FXF46_05975	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FXF46_06010	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FXF46_06015	ENOG4105CKK	Glycosyl transferase, family 2
FXF46_06020	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FXF46_06025	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FXF46_06035	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
FXF46_06045	ENOG4107RTZ	reductase
FXF46_06065	ENOG4108K4C	ec 3.1.3.12
FXF46_06090	ENOG4105C26	Dehydrogenase
FXF46_06095	ENOG4108SHN	Glycosyl transferase, family 2
FXF46_06125	ENOG4105II7	pyrroline-5-carboxylate reductase
FXF46_06140	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FXF46_06145	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FXF46_06155	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FXF46_06165	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FXF46_06170	ENOG4105D2S	major facilitator superfamily
FXF46_06175	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FXF46_06180	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FXF46_06200	ENOG4105C3G	gtp-binding protein
FXF46_06205	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FXF46_06210	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FXF46_06220	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FXF46_06235	ENOG4105C5X	domain protein
FXF46_06290	ENOG4108UQY	Iron-storage protein
FXF46_06305	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FXF46_06310	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FXF46_06320	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FXF46_06330	ENOG4107QUT	magnesium and cobalt transport protein CorA
FXF46_06335	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FXF46_06340	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FXF46_06350	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FXF46_06355	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FXF46_06365	ENOG4105CDU	Replicative dna helicase
FXF46_06520	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FXF46_06525	ENOG4105DBV	ornithine carbamoyltransferase
FXF46_06530	ENOG4105C8Y	Acetylornithine aminotransferase
FXF46_06535	ENOG4107UQD	Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity)
FXF46_06540	ENOG4105KC9	Modulates RecA activity (By similarity)
FXF46_06555	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
FXF46_06560	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
FXF46_06565	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
FXF46_06570	ENOG4105DTN	riboflavin biosynthesis protein ribF
FXF46_06595	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FXF46_06600	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FXF46_06610	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FXF46_06615	ENOG4105CXG	d-lactate dehydrogenase
FXF46_06620	ENOG4105CPQ	Dehydrogenase
FXF46_06630	ENOG4108R85	Short chain dehydrogenase
FXF46_06635	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FXF46_06640	ENOG4105C2J	ABC transporter
FXF46_06645	ENOG4105CNN	ABC, transporter
FXF46_06660	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FXF46_06685	ENOG4105CN1	protease
FXF46_06695	ENOG4105C79	DNA protecting protein DprA
FXF46_06700	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FXF46_06705	ENOG4105CD3	dihydroorotase
FXF46_06710	ENOG4105CXT	aspartate transcarbamylase
FXF46_06715	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FXF46_06735	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FXF46_06740	ENOG4105CSM	endonuclease III
FXF46_06745	ENOG4108JJ7	ABC transporter
FXF46_06750	ENOG4105CPN	adenine deaminase
FXF46_06760	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FXF46_06765	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FXF46_06770	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FXF46_06775	ENOG4107S5I	aldo keto reductase
FXF46_06780	ENOG4108JQC	penicillin-binding protein 1A
FXF46_06815	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FXF46_06825	ENOG4107TXM	Nad-dependent epimerase dehydratase
FXF46_06830	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FXF46_06835	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FXF46_06840	ENOG4105CG3	alpha amylase, catalytic region
FXF46_06845	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FXF46_06855	ENOG4105CE4	GlcNAc 6-P deacetylase
FXF46_06865	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FXF46_06880	ENOG4105E98	transcriptional regulator DeoR family
FXF46_06900	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FXF46_06905	ENOG4105C5Q	Transcriptional regulator
FXF46_06915	ENOG4105C5R	Aminotransferase
FXF46_06930	ENOG4105F1S	paraquat-inducible protein a
FXF46_06935	ENOG4105DY2	Paraquat-inducible protein b
FXF46_06950	ENOG410683Z	Preprotein translocase SecE subunit
FXF46_06965	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FXF46_06970	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FXF46_06975	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FXF46_06980	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FXF46_06985	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FXF46_07035	ENOG4107T8Q	Glycosyl transferase (Group 1
FXF46_07050	ENOG4108TJN	glycosyl transferase group 1
FXF46_07055	ENOG41084CK	capsule polysaccharide
FXF46_07075	ENOG4105EW9	transcriptional regulator AsnC family
FXF46_07080	ENOG4105C26	Dehydrogenase
FXF46_07090	ENOG4105DC7	peptidase M24
FXF46_07095	ENOG41079KZ	Major Facilitator Superfamily
FXF46_07110	ENOG4105CE1	Ferrous iron transport protein b
FXF46_07120	ENOG4105VPX	protein, conserved in bacteria
FXF46_07135	ENOG4105E3B	Multicopper oxidase
FXF46_07145	ENOG4105C59	p-type ATPase
FXF46_07150	ENOG4105CNM	Receptor
FXF46_07155	ENOG4105CQ0	ABC transporter
FXF46_07185	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FXF46_07210	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FXF46_07225	ENOG4105C7W	Xanthine dehydrogenase
FXF46_07240	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FXF46_07245	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FXF46_07250	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FXF46_07265	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
FXF46_07270	ENOG4105CQZ	Histidine kinase
FXF46_07305	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
FXF46_07310	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FXF46_07315	ENOG4105CI3	gtp-binding protein typa
FXF46_07325	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FXF46_07330	ENOG4105CAY	ferredoxin--nadp reductase
FXF46_07335	ENOG4105CG5	Glycosyl transferase (Group 1
FXF46_07345	ENOG4108E87	P-loop hydrolase UPF0079
FXF46_07360	ENOG4105K63	Thioredoxin
FXF46_07365	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FXF46_07380	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_07435	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FXF46_07455	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FXF46_07460	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FXF46_07510	ENOG4105CMR	udp-glucose 4-epimerase
FXF46_07525	ENOG4105ECX	polysaccharide export
FXF46_07530	ENOG4105EY8	ABC transporter
FXF46_07545	ENOG4105C26	Dehydrogenase
FXF46_07555	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FXF46_07565	ENOG4105C1G	acyl-Coa dehydrogenase
FXF46_07570	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
FXF46_07585	ENOG4105TPV	
FXF46_07595	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FXF46_07600	ENOG4107QNK	)-transporter
FXF46_07605	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FXF46_07620	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FXF46_07630	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FXF46_07645	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FXF46_07650	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FXF46_07655	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FXF46_07660	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
FXF46_07675	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FXF46_07680	ENOG4105CAT	Cytidine monophosphate kinase
FXF46_07685	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FXF46_07695	ENOG4107RRZ	synthase
FXF46_07720	ENOG4105CPK	Glycosyl transferase (Group 1
FXF46_07730	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
FXF46_07735	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FXF46_07745	ENOG4105DU0	nucleoside hydrolase
FXF46_07755	ENOG4105EW9	transcriptional regulator AsnC family
FXF46_07775	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
FXF46_07780	ENOG4105EHG	Permease protein
FXF46_07785	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FXF46_07790	ENOG4105S10	periplasmic binding protein
FXF46_07795	ENOG4105E2D	ec 3.2.1.52
FXF46_07800	ENOG4105C9K	Endothelin-converting enzyme 1
FXF46_07805	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FXF46_07820	ENOG4105SYT	Methylenetetrahydrofolate reductase
FXF46_07825	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FXF46_07840	ENOG41080HT	Transcriptional regulator, arsr family
FXF46_07845	ENOG4105D3R	alkyl hydroperoxide reductase
FXF46_07895	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_07915	ENOG4108IU3	tonb-dependent siderophore receptor
FXF46_07930	ENOG4107E2E	PKHD-type hydroxylase
FXF46_07940	ENOG4108ZZF	transport protein (ExbD)
FXF46_07955	ENOG4105CPN	adenine deaminase
FXF46_07970	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FXF46_07975	ENOG4105CBT	Fructose-1,6-bisphosphatase
FXF46_07980	ENOG4105D6E	homoserine dehydrogenase
FXF46_07985	ENOG4105CHM	Aminotransferase
FXF46_07995	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FXF46_08005	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FXF46_08010	ENOG4105D00	flagellar biosynthetic protein flhB
FXF46_08015	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FXF46_08020	ENOG4105VS8	Flagellar biosynthetic protein fliq
FXF46_08025	ENOG4105UVF	flagellar hook-basal body complex protein fliE
FXF46_08030	ENOG4108ZC9	flagellar basal-body rod protein flgc
FXF46_08035	ENOG4105SFI	flagellar basal-body rod protein
FXF46_08045	ENOG4105CN7	Flagellar biosynthetic protein FliP
FXF46_08050	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FXF46_08065	ENOG4105EEI	dihydropteroate synthase
FXF46_08070	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FXF46_08085	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FXF46_08090	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FXF46_08095	ENOG4105MFV	ABC-2 type transporter
FXF46_08130	ENOG4108VYJ	response regulator receiver protein
FXF46_08135	ENOG4105CBS	Chea signal transduction histidine kinase
FXF46_08140	ENOG4108V3W	Chemotaxis protein, CheW
FXF46_08145	ENOG4105BZU	Histidine kinase
FXF46_08150	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FXF46_08155	ENOG4108VYJ	response regulator receiver protein
FXF46_08170	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FXF46_08185	ENOG4105E4C	Lytic transglycosylase catalytic
FXF46_08190	ENOG4105IE8	Alpha-ketoglutarate permease
FXF46_08195	ENOG4108UM1	dedA family
FXF46_08205	ENOG4105CN1	protease
FXF46_08215	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FXF46_08220	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FXF46_08225	ENOG4105CDA	abc transporter atp-binding protein
FXF46_08230	ENOG4105E5Q	amino acid AbC transporter
FXF46_08240	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
FXF46_08250	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FXF46_08265	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FXF46_08270	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FXF46_08275	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FXF46_08280	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FXF46_08285	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FXF46_08320	ENOG4105CSA	Coproporphyrinogen iii oxidase
FXF46_08325	ENOG4105DFH	Transport of potassium into the cell (By similarity)
FXF46_08330	ENOG4105DFA	alanine racemase domain protein
FXF46_08335	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FXF46_08340	ENOG4105E0F	Histidine kinase
FXF46_08345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FXF46_08350	ENOG4105C6F	GntR Family Transcriptional Regulator
FXF46_08355	ENOG4105CZV	ABC transporter
FXF46_08365	ENOG4105E2X	shikimate dehydrogenase
FXF46_08370	ENOG4105E0F	Histidine kinase
FXF46_08400	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FXF46_08410	ENOG4107STW	synthase
FXF46_08415	ENOG4108FN7	Aldo keto reductase
FXF46_08425	ENOG4105CKI	cobalamin synthesis protein
FXF46_08455	ENOG4105CMQ	Chloride channel
FXF46_08460	ENOG4105EJQ	L-serine dehydratase
FXF46_08470	ENOG4105PGM	cation diffusion facilitator family transporter
FXF46_08490	ENOG4105CJ1	ABC, transporter
FXF46_08505	ENOG4108TEB	UPF0114 protein
FXF46_08510	ENOG4105DZ0	fad dependent oxidoreductase
FXF46_08530	ENOG4105C2I	pirin domain protein
FXF46_08535	ENOG4105CC0	LysR family Transcriptional regulator
FXF46_08540	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FXF46_08560	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FXF46_08565	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
FXF46_08575	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FXF46_08580	ENOG4105BZU	Histidine kinase
FXF46_08595	ENOG4105C9Q	fumarate hydratase class II
FXF46_08610	ENOG4105KWW	Biogenesis protein
FXF46_08615	ENOG4107QX9	Thiol disulfide interChange protein
FXF46_08620	ENOG4105DA4	cytochrome c-type biogenesis protein
FXF46_08625	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FXF46_08630	ENOG41060IM	Heme exporter protein
FXF46_08655	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FXF46_08675	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FXF46_08685	ENOG4105D1H	recombination factor protein RarA
FXF46_08690	ENOG4105EI2	Pseudouridine synthase
FXF46_08705	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FXF46_08710	ENOG4105NWN	ApaG protein
FXF46_08735	ENOG4105CEP	NADH dehydrogenase
FXF46_08740	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FXF46_08750	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FXF46_08755	ENOG4105CDY	transcriptional regulatory protein
FXF46_08760	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FXF46_08765	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FXF46_08770	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FXF46_08775	ENOG4107YD3	Thioesterase
FXF46_08780	ENOG4105E02	MotA TolQ exbB proton channel
FXF46_08785	ENOG4108ZZF	transport protein (ExbD)
FXF46_08795	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FXF46_08800	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FXF46_08810	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FXF46_08820	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FXF46_08825	ENOG4105DWF	phosphomethylpyrimidine kinase
FXF46_08830	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
FXF46_08835	ENOG4108JIR	Flagellum-specific ATP synthase
FXF46_08855	ENOG4105C88	aminopeptidase
FXF46_08875	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FXF46_08895	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FXF46_08900	ENOG4108J5G	6-phosphogluconate dehydrogenase
FXF46_08905	ENOG410667J	hydrolase
FXF46_08910	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FXF46_08915	ENOG4105E66	phosphoriboisomerase A
FXF46_08920	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FXF46_08925	ENOG4108UPT	UPF0178 protein
FXF46_08930	ENOG4105EGI	Transcriptional regulator
FXF46_08935	ENOG4105C26	Dehydrogenase
FXF46_08940	ENOG4108Z0Z	intracellular protease Pfpi family
FXF46_08950	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FXF46_08975	ENOG4105CPN	adenine deaminase
FXF46_08980	ENOG4106BSU	Entericidin B
FXF46_08985	ENOG4107QNK	)-transporter
FXF46_09005	ENOG4108V0P	LemA family
FXF46_09010	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FXF46_09030	ENOG4105C8N	cysteinyl-tRNA synthetase
FXF46_09035	ENOG4107QI1	Mate efflux family protein
FXF46_09040	ENOG4105F27	Major Facilitator
FXF46_09050	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FXF46_09065	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FXF46_09070	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
FXF46_09085	ENOG4107B2H	carbonic anhydrase
FXF46_09090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FXF46_09105	ENOG4105D49	3-dehydroquinate synthase
FXF46_09115	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FXF46_09120	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FXF46_09165	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FXF46_09170	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FXF46_09175	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
FXF46_09180	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
FXF46_09195	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FXF46_09200	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FXF46_09205	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FXF46_09210	ENOG4105C3F	Signal peptidase i
FXF46_09215	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FXF46_09220	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FXF46_09225	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FXF46_09230	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FXF46_09235	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FXF46_09245	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FXF46_09250	ENOG4105DZP	Membrane-associated zinc metalloprotease
FXF46_09255	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FXF46_09265	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FXF46_09270	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FXF46_09275	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FXF46_09280	ENOG4105GYT	Protein of unknown function (DUF1009)
FXF46_09285	ENOG4108UYE	Lactoylglutathione lyase
FXF46_09295	ENOG4105VG0	50S ribosomal protein l34
FXF46_09300	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FXF46_09305	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FXF46_09310	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FXF46_09315	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FXF46_09320	ENOG4105CAS	nag kinase
FXF46_09330	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FXF46_09335	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FXF46_09345	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FXF46_09350	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FXF46_09355	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FXF46_09360	ENOG4108ZNX	Heat shock protein
FXF46_09370	ENOG4105M4H	endoribonuclease L-psp
FXF46_09385	ENOG4105EDR	glucose galactose transporter
FXF46_09390	ENOG4105C5H	ABC transporter
FXF46_09415	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FXF46_09420	ENOG4108IUZ	ABC transporter
FXF46_09435	ENOG4105C2X	Arabinose 5-phosphate isomerase
FXF46_09465	ENOG4108YYH	Nadph-dependent fmn reductase
FXF46_09470	ENOG4105E2A	Dehydrogenase
FXF46_09495	ENOG4105D64	Mechanosensitive ion channel
FXF46_09505	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
FXF46_09510	ENOG4105C2M	dna polymerase I
FXF46_09535	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FXF46_09545	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FXF46_09555	ENOG4105C03	ribonuclease
FXF46_09565	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
FXF46_09570	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FXF46_09575	ENOG4107TSN	permease
FXF46_09605	ENOG4105CJN	penicillin-binding protein
FXF46_09610	ENOG4105CNI	cell division protein FtsW
FXF46_09615	ENOG4105CPQ	Dehydrogenase
FXF46_09625	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FXF46_09630	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FXF46_09655	ENOG4105C9M	aspartyl-trna synthetase
FXF46_09670	ENOG4105CGK	Exodeoxyribonuclease III
FXF46_09675	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FXF46_09680	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FXF46_09685	ENOG4105C75	arginyL-tRNA synthetase
FXF46_09695	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FXF46_09700	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FXF46_09710	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FXF46_09715	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FXF46_09735	ENOG4105DP0	ferredoxin-NADP reductase
FXF46_09740	ENOG4105DC8	reductase
FXF46_09745	ENOG4105DSW	Fusaric acid resistance protein
FXF46_09760	ENOG4105CF1	Alkylated DNA repair protein
FXF46_09765	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FXF46_09785	ENOG4105EWC	Purine nucleoside phosphorylase
FXF46_09790	ENOG4105DPN	Oligoendopeptidase f
FXF46_09815	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FXF46_09820	ENOG4107WI4	Aldose-1-epimerase
FXF46_09825	ENOG4108RRZ	Transcription elongation factor GreB
FXF46_09835	ENOG4105D7Z	glutathione synthase
FXF46_09840	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FXF46_09850	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FXF46_09860	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FXF46_09865	ENOG4105C1V	Peptidase, M16
FXF46_09870	ENOG4105D98	threonine synthase
FXF46_09890	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FXF46_09895	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FXF46_09900	ENOG4105CJR	Integral membrane protein (MviN
FXF46_09915	ENOG4108V06	Glutathione peroxidase
FXF46_09920	ENOG4105D9N	nucleoside
FXF46_09930	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FXF46_09935	ENOG4105D6S	protein involved in catabolism of external DNA
FXF46_09940	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FXF46_09945	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FXF46_09955	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FXF46_09975	ENOG4105CA0	peroxidase
FXF46_09985	ENOG4105PWE	CRISPR-associated protein cas2
FXF46_09990	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
FXF46_10000	ENOG4108VWQ	crispr-associated protein
FXF46_10005	ENOG41060M0	Crispr-associated protein, cse4 family
FXF46_10020	ENOG4105DTT	CRISPR-associated helicase, cas3
FXF46_10035	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FXF46_10040	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FXF46_10050	ENOG4105EMU	Dehydrogenase
FXF46_10065	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FXF46_10070	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FXF46_10085	ENOG4105DK7	lysyl-tRNA synthetase
FXF46_10095	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FXF46_10100	ENOG4108RG0	uracil-dna glycosylase
FXF46_10105	ENOG4105M7V	2'-5' rna ligase
FXF46_10110	ENOG4105HFZ	Membrane
FXF46_10125	ENOG4105CCU	oxidase (Subunit III)
FXF46_10130	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
FXF46_10140	ENOG4105EI2	Pseudouridine synthase
FXF46_10150	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FXF46_10170	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FXF46_10180	ENOG4108Z6Z	Transcriptional regulator
FXF46_10195	ENOG4105C5H	ABC transporter
FXF46_10200	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FXF46_10205	ENOG4105CKK	Glycosyl transferase, family 2
FXF46_10220	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FXF46_10225	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FXF46_10230	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
FXF46_10235	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FXF46_10250	ENOG4105F27	Major Facilitator
FXF46_10270	ENOG4105KG3	cytidine deaminase
FXF46_10300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FXF46_10315	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FXF46_10320	ENOG4105CH7	arginosuccinase
FXF46_10325	ENOG4107ZT5	Thiol disulfide interchange protein
FXF46_10330	ENOG4107ZT5	Thiol disulfide interchange protein
FXF46_10345	ENOG4105E2X	shikimate dehydrogenase
FXF46_10350	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FXF46_10355	ENOG4107RZZ	dna polymerase iii epsilon subunit
FXF46_10365	ENOG4107RJ7	Glycosyl transferase (Group 1
FXF46_10370	ENOG4105CAQ	asparagine synthetase
FXF46_10375	ENOG4105CD3	dihydroorotase
FXF46_10400	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FXF46_10405	ENOG4107QNK	)-transporter
FXF46_10410	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FXF46_10420	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FXF46_10430	ENOG4105D1K	glutamate--cysteine ligase
FXF46_10440	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FXF46_10460	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FXF46_10465	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FXF46_10480	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FXF46_10485	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FXF46_10490	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FXF46_10495	ENOG4108Z9K	Osmotically inducible protein
FXF46_10500	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FXF46_10510	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FXF46_10520	ENOG4105EAH	synthase
FXF46_10525	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FXF46_10530	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FXF46_10550	ENOG4108ZM9	phosphoglycerate mutase
FXF46_10555	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FXF46_10565	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FXF46_10570	ENOG4108R9S	DSBA oxidoreductase
FXF46_10580	ENOG4107RCQ	(CBS) domain
FXF46_10585	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FXF46_10590	ENOG4105C9A	Phoh family
FXF46_10595	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FXF46_10605	ENOG4105CFU	surface antigen
FXF46_10625	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FXF46_10630	ENOG4108VJ1	Transcriptional regulator (CarD family
FXF46_10635	ENOG4105FFC	UPF0187 protein
FXF46_10640	ENOG4107QPD	alcohol dehydrogenase
FXF46_10645	ENOG4105C4W	S-formylglutathione hydrolase
FXF46_10655	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FXF46_10660	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FXF46_10690	ENOG4105CFG	Acts as a chaperone (By similarity)
FXF46_10695	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FXF46_10710	ENOG4105C9K	Endothelin-converting enzyme 1
FXF46_10720	ENOG4105CHR	reductase
FXF46_10730	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FXF46_10740	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FXF46_10750	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FXF46_10755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FXF46_10760	ENOG4105HHA	aminodeoxychorismate lyase
FXF46_10770	ENOG4105ECY	inositol monophosphatase
FXF46_10810	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FXF46_10825	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FXF46_10830	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FXF46_10835	ENOG4107RCI	amp-dependent synthetase and ligase
FXF46_10865	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FXF46_10870	ENOG4105CSV	Glutaminase
FXF46_10875	ENOG4105E0K	tonB-dependent siderophore receptor
FXF46_10905	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
FXF46_10910	ENOG4105KST	dependent repressor
FXF46_10920	ENOG410804X	Transcriptional regulator
FXF46_10925	ENOG4105CMG	Carbohydrate kinase
FXF46_10945	ENOG4108PQ7	sgc region transcriptional regulator
FXF46_10955	ENOG4107ENK	receptor
FXF46_10960	ENOG4108YNN	Heme oxygenase
FXF46_10965	ENOG4107R4I	Periplasmic binding protein
FXF46_10970	ENOG4105EHG	Permease protein
FXF46_10975	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FXF46_10985	ENOG4105E98	transcriptional regulator DeoR family
FXF46_10990	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FXF46_10995	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FXF46_11000	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FXF46_11005	ENOG4105DWT	malate dehydrogenase (quinone)
FXF46_11010	ENOG4105CQB	FAD linked oxidase domain protein
FXF46_11020	ENOG4105C3R	Methionine synthase
FXF46_11035	ENOG4105CC0	LysR family Transcriptional regulator
FXF46_11040	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FXF46_11045	ENOG4108YYC	ycei family
FXF46_11050	ENOG4108K3A	Glutathione S-transferase
FXF46_11075	ENOG4105CHH	sulfate transporter
FXF46_11080	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FXF46_11085	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
FXF46_11100	ENOG4108RVA	ribokinase
FXF46_11115	ENOG4105DHJ	ABC, transporter
FXF46_11130	ENOG4105BZU	Histidine kinase
FXF46_11195	ENOG4105F1N	DNA alkylation repair
FXF46_11220	ENOG4105EXC	Acyl-transferase
FXF46_11245	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FXF46_11310	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FXF46_11350	ENOG4105EHZ	conserved protein UCP016719
FXF46_11380	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FXF46_11400	ENOG4105DUX	Transporter
FXF46_11410	ENOG4107QTZ	amino acid
FXF46_11425	ENOG4105DC7	peptidase M24
FXF46_11435	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FXF46_11455	ENOG4107XBN	GntR Family Transcriptional Regulator
FXF46_11465	ENOG4105D05	Receptor
FXF46_11495	ENOG4105EBR	Carboxylesterase
FXF46_11505	ENOG4105DTQ	mandelate racemase muconate lactonizing
FXF46_11510	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
FXF46_11520	ENOG4105Q56	cytochrome P450
FXF46_11525	ENOG4105CHR	reductase
FXF46_11535	ENOG4107REC	cytoplasmic protein
FXF46_11540	ENOG4107REC	cytoplasmic protein
FXF46_11545	ENOG4107R1Q	Membrane protein FdrA
FXF46_11550	ENOG4105DEF	Extracellular solute-binding protein, family 5
FXF46_11555	ENOG4107HP6	Transcriptional regulator
FXF46_11635	ENOG4105ETS	cytosine purines uracil thiamine allantoin
FXF46_11645	ENOG4105C26	Dehydrogenase
FXF46_11650	ENOG4108M8W	Monooxygenase
FXF46_11655	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FXF46_11665	ENOG4105FVZ	flavin reductase domain protein, FMN-binding
FXF46_11670	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FXF46_11685	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FXF46_11690	ENOG4105WIU	sarcosine oxidase delta subunit
FXF46_11695	ENOG4105DDR	sarcosine oxidase (Beta subunit)
FXF46_11700	ENOG410811B	TRANSCRIPTIONal
FXF46_11710	ENOG4105EYU	Glutamine amido-transferase
FXF46_11715	ENOG4105M90	Glutamate synthase alpha subunit domain protein
FXF46_11720	ENOG4105CBC	glutamate synthase
FXF46_11735	ENOG4105C26	Dehydrogenase
FXF46_11765	ENOG4105GVF	(ABC) transporter
FXF46_11785	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
FXF46_11795	ENOG4107T8P	acyl-Coa dehydrogenase
FXF46_11815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FXF46_11820	ENOG4108JQ5	ABC transporter
FXF46_11835	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
FXF46_11845	ENOG4107QRT	dEAD DEAH box helicase
FXF46_11860	ENOG4105BZU	Histidine kinase
FXF46_11880	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FXF46_11900	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FXF46_11920	ENOG4105CND	Glycosyl transferase, family 2
FXF46_11930	ENOG4105C26	Dehydrogenase
FXF46_11935	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FXF46_11940	ENOG4108IND	Tetr family transcriptional regulator
FXF46_11975	ENOG4105CYM	Glutathione S-transferase
FXF46_11980	ENOG4105CYM	Glutathione S-transferase
FXF46_11990	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FXF46_11995	ENOG4105CYM	Glutathione S-transferase
FXF46_12000	ENOG4105CC0	LysR family Transcriptional regulator
FXF46_12020	ENOG4105CNM	Receptor
FXF46_12060	ENOG4108IYU	L-aspartate oxidase
FXF46_12090	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FXF46_12095	ENOG4105BZU	Histidine kinase
FXF46_12140	ENOG4105ETE	Transcriptional regulator (LacI family
FXF46_12145	ENOG4107ZSV	Receptor
FXF46_12150	ENOG4105EBR	Carboxylesterase
FXF46_12155	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
FXF46_12200	ENOG4105DZG	Dehydrogenase
FXF46_12220	ENOG4105EB3	Histidine kinase
FXF46_12280	ENOG4107NQ8	LysR family Transcriptional regulator
FXF46_12295	ENOG4105P4J	Allophanate hydrolase, subunit 1
FXF46_12300	ENOG4107R7A	Allophanate hydrolase subunit 2
FXF46_12305	ENOG4105E7W	lamb ycsf family protein
FXF46_12310	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FXF46_12315	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FXF46_12330	ENOG4105E7W	lamb ycsf family protein
FXF46_12355	ENOG4108MI0	Resistance protein
FXF46_12360	ENOG4105J12	Multidrug resistance protein mdtN
FXF46_12385	ENOG4108RF4	Tetr family transcriptional regulator
FXF46_12390	ENOG41079KZ	Major Facilitator Superfamily
FXF46_12395	ENOG4105CPN	adenine deaminase
FXF46_12410	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FXF46_12415	ENOG4107QRI	Phosphoketolase
FXF46_12485	ENOG4105ECQ	AraC Family Transcriptional Regulator
FXF46_12500	ENOG4105IE8	Alpha-ketoglutarate permease
FXF46_12505	ENOG4105CPQ	Dehydrogenase
FXF46_12510	ENOG4105ID8	Transcriptional regulator, ARAC family
FXF46_12515	ENOG4105F27	Major Facilitator
FXF46_12520	ENOG4105TW1	Carbohydrate-selective porin OprB
FXF46_12525	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
FXF46_12535	ENOG4105C7W	Xanthine dehydrogenase
FXF46_12540	ENOG4105EQ0	Major Facilitator superfamily
FXF46_12575	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FXF46_12595	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FXF46_12600	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FXF46_12615	ENOG4105CF7	AraC family transcriptional regulator
FXF46_12655	ENOG4105CP7	Triose-phosphate isomerase
FXF46_12665	ENOG4108YZG	isomerase
FXF46_12675	ENOG4105C2J	ABC transporter
FXF46_12680	ENOG4105CNN	ABC, transporter
FXF46_12685	ENOG4105CMT	Dihydroxyacetone kinase
FXF46_12700	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FXF46_12730	ENOG4105D7T	ABC transporter
FXF46_12735	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FXF46_12745	ENOG4105FVZ	flavin reductase domain protein, FMN-binding
FXF46_12755	ENOG4107NQ8	LysR family Transcriptional regulator
FXF46_12760	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
FXF46_12765	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FXF46_12775	ENOG4108T2C	cysteine dioxygenase type I
FXF46_12785	ENOG4108KC1	acyl-Coa dehydrogenase
FXF46_12790	ENOG4105GVF	(ABC) transporter
FXF46_12795	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FXF46_12800	ENOG4105E2Y	ABC, transporter
FXF46_12810	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
FXF46_12815	ENOG4105E0K	tonB-dependent siderophore receptor
FXF46_12835	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FXF46_12840	ENOG4105CK2	sodium dicarboxylate symporter
FXF46_12850	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FXF46_12860	ENOG4107QUY	Guanine deaminase
FXF46_12890	ENOG4108JQ9	ABC transporter
FXF46_12895	ENOG4105UIB	(ABC) transporter
FXF46_12915	ENOG4105C09	Bile acid
FXF46_12920	ENOG4105HEI	LysR family (Transcriptional regulator
FXF46_12940	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
FXF46_12955	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FXF46_12960	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FXF46_13005	ENOG4105QUC	reductase
FXF46_13025	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
FXF46_13030	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FXF46_13035	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FXF46_13040	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FXF46_13045	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FXF46_13090	ENOG4105E2V	Glycosyltransferase 36
FXF46_13095	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FXF46_13115	ENOG4105E0K	tonB-dependent siderophore receptor
FXF46_13130	ENOG4105EHG	Permease protein
FXF46_13135	ENOG4105CHR	reductase
FXF46_13140	ENOG4105C6Z	Gluconate
FXF46_13145	ENOG4105DEN	Luciferase family
FXF46_13160	ENOG4105KXX	peptidase s58 dmpa
FXF46_13165	ENOG4108JQ7	(ABC) transporter
FXF46_13175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FXF46_13185	ENOG4105DEF	Extracellular solute-binding protein, family 5
FXF46_13190	ENOG4105CPU	Monooxygenase
FXF46_13195	ENOG4107ZSV	Receptor
FXF46_13210	ENOG4105C2C	drug resistance transporter, Bcr CflA
FXF46_13225	ENOG4107FQ9	ethanolamine ammonia-lyase
FXF46_13230	ENOG4105CPD	ethanolamine ammonia-lyase
FXF46_13240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FXF46_13250	ENOG4105DGW	oligopeptidase A
FXF46_13255	ENOG4105CA0	peroxidase
FXF46_13265	ENOG4105CJ3	phosphate transporter
FXF46_13270	ENOG4108IU3	tonb-dependent siderophore receptor
FXF46_13280	ENOG4105CHR	reductase
FXF46_13285	ENOG4108IJ9	(ABC) transporter
FXF46_13305	ENOG4105EF1	ribulokinase
FXF46_13315	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FXF46_13330	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
FXF46_13345	ENOG4107TTD	cytosine deaminase
FXF46_13350	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FXF46_13355	ENOG4105D7T	ABC transporter
FXF46_13380	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FXF46_13390	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
FXF46_13400	ENOG4105DAE	Methylenetetrahydrofolate reductase
FXF46_13430	ENOG4105DQ4	alcohol dehydrogenase
FXF46_13445	ENOG4108IYU	L-aspartate oxidase
FXF46_13450	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FXF46_13455	ENOG4105HSS	phospholipase C
FXF46_13470	ENOG4105CKI	cobalamin synthesis protein
FXF46_13475	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FXF46_13480	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FXF46_13485	ENOG4105EIX	cytochrome c1
FXF46_13495	ENOG4105CA0	peroxidase
FXF46_13505	ENOG4105CGZ	zinc metallopeptidase
FXF46_13520	ENOG4105EYH	Exonuclease
FXF46_13525	ENOG4107RH8	nuclease SbcCD subunit D
FXF46_13540	ENOG4105CHR	reductase
FXF46_13550	ENOG4105CEP	NADH dehydrogenase
FXF46_13555	ENOG4105CSH	Transporter
FXF46_13570	ENOG4105CH2	amidohydrolase
FXF46_13585	ENOG4105C7N	Xanthine uracil vitamin C permease
FXF46_13595	ENOG4105FDP	GntR family transcriptional regulator
FXF46_13600	ENOG4105C8Q	Methyl-accepting chemotaxis
FXF46_13605	ENOG4107S1E	Beta-lactamase
FXF46_13700	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FXF46_13705	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FXF46_13735	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FXF46_13740	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FXF46_13760	ENOG4105D06	uba thif-type nad fad binding protein
FXF46_13775	ENOG4105CA9	Pyruvate kinase
FXF46_13780	ENOG4105EVN	Prephenate dehydrogenase
FXF46_13800	ENOG4105FBD	synthase
FXF46_13805	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FXF46_13815	ENOG4105FE1	phytoene synthase
FXF46_13840	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FXF46_13860	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FXF46_13880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FXF46_13895	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FXF46_13910	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FXF46_13915	ENOG4105W0E	50S ribosomal protein L33
FXF46_13925	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FXF46_13935	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FXF46_13940	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FXF46_13950	ENOG4105CP7	Triose-phosphate isomerase
FXF46_13960	ENOG4105CRQ	synthase (Component I)
FXF46_13965	ENOG4105DDQ	anthranilate synthase
FXF46_13970	ENOG4107QYG	anthranilate phosphoribosyltransferase
FXF46_13975	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FXF46_13980	ENOG4108JYK	Dehydrogenase
FXF46_13985	ENOG4105CPP	Dehydrogenase, E1 component
FXF46_13990	ENOG4105C7S	Dehydrogenase
FXF46_14000	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FXF46_14005	ENOG4108Z1B	Cyclase dehydrase
FXF46_14015	ENOG4105CEV	competence damage-inducible protein
FXF46_14025	ENOG4108ZCF	integral membrane protein
FXF46_14030	ENOG4105C83	adenylosuccinate lyase
FXF46_14035	ENOG4107QPR	SAICAR synthetase
FXF46_14040	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
FXF46_14050	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FXF46_14055	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FXF46_14080	ENOG4105D52	delta-aminolevulinic acid dehydratase
FXF46_14085	ENOG4105CUB	amino acid
FXF46_14090	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FXF46_14100	ENOG4105CWC	Acetylornithine deacetylase
FXF46_14110	ENOG4107Y2G	Glycosyl transferase (Group 1
FXF46_14115	ENOG4105C1J	atp-dependent rna helicase
FXF46_14340	ENOG4108TFU	terminase (Small subunit)
FXF46_14370	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
FXF46_14530	ENOG4106TD9	Diguanylate cyclase
FXF46_14535	ENOG4105C54	Major Facilitator superfamily
FXF46_14550	ENOG4105CMG	Carbohydrate kinase
FXF46_14595	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FXF46_14600	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FXF46_14605	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FXF46_14610	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FXF46_14635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FXF46_14640	ENOG4107RBB	ABC transporter, permease
FXF46_14645	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FXF46_14660	ENOG4108HWS	Histidine kinase
FXF46_14690	ENOG4108Z7F	N-acetyltransferase
FXF46_14695	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FXF46_14705	ENOG4105W5Q	DNA repair protein (RadC
FXF46_14710	ENOG4105W5Q	DNA repair protein (RadC
FXF46_14715	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FXF46_14720	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FXF46_14735	ENOG4108ZNX	Heat shock protein
FXF46_14740	ENOG41082FS	50S ribosomal protein L31
FXF46_14745	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FXF46_14755	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FXF46_14760	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FXF46_14770	ENOG4105C5H	ABC transporter
FXF46_14775	ENOG41074H6	response regulator
FXF46_14795	ENOG4108JJ9	ABC, transporter
FXF46_14800	ENOG4108JJ8	(ABC) transporter
FXF46_14810	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FXF46_14820	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FXF46_14825	ENOG4107XZX	Involved in the transcription termination process (By similarity)
FXF46_14830	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FXF46_14865	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FXF46_14875	ENOG4105C01	Dihydroxy-acid dehydratase
FXF46_14885	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FXF46_14900	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FXF46_14905	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FXF46_14910	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FXF46_14915	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FXF46_14920	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FXF46_14925	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FXF46_14930	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FXF46_14935	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FXF46_14940	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FXF46_14950	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FXF46_14955	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FXF46_14960	ENOG4105CQB	FAD linked oxidase domain protein
FXF46_14980	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FXF46_14985	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FXF46_14995	ENOG4105DUX	Transporter
FXF46_15005	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FXF46_15010	ENOG4105F8V	Hydrolase, tatD family
FXF46_15015	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FXF46_15020	ENOG4107QRG	dna polymerase iii
FXF46_15025	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FXF46_15030	ENOG4105DZ1	carboxypeptidase
FXF46_15040	ENOG4105CVE	Lytic murein transglycosylase
FXF46_15060	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FXF46_15065	ENOG4105CUB	amino acid
FXF46_15090	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FXF46_15100	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FXF46_15105	ENOG4105CUT	histidyl-tRNA synthetase
FXF46_15110	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FXF46_15125	ENOG4105CFH	Aspartokinase
FXF46_15130	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FXF46_15135	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FXF46_15145	ENOG4105VW4	glutaredoxin 3
FXF46_15175	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FXF46_15190	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FXF46_15225	ENOG4105CB5	ATP-dependent DNA helicase recG
FXF46_15230	ENOG4105BZU	Histidine kinase
FXF46_15240	ENOG4105VEQ	Cold shock protein
FXF46_15245	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FXF46_15250	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FXF46_15260	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FXF46_15270	ENOG4108JQ1	Dehydrogenase
FXF46_15275	ENOG4105C0P	Mg chelatase subunit ChlI
FXF46_15285	ENOG4105C28	cystathionine
FXF46_15290	ENOG4105KHC	sulfurtransferase
FXF46_15295	ENOG4105IPI	Membrane
FXF46_15305	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FXF46_15310	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FXF46_15315	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FXF46_15325	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
FXF46_15330	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FXF46_15335	ENOG4105CE9	30S ribosomal protein S2
FXF46_15340	ENOG4105C0B	DNA polymerase III (alpha subunit)
FXF46_15345	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FXF46_15355	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FXF46_15365	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FXF46_15370	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FXF46_15380	ENOG4105K70	DNA-binding protein
FXF46_15385	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FXF46_15390	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FXF46_15395	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FXF46_15400	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FXF46_15410	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FXF46_15425	ENOG4105C1J	atp-dependent rna helicase
FXF46_15430	ENOG4107QS4	23S rRNA
FXF46_15435	ENOG4108Z4V	iron-sulfur cluster assembly
FXF46_15440	ENOG4105VG1	fes assembly suf system protein
FXF46_15450	ENOG4105JRK	feS assembly protein SufD
FXF46_15455	ENOG4105C3K	feS assembly ATPase SufC
FXF46_15470	ENOG4106BRA	Membrane
FXF46_15485	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FXF46_15490	ENOG4105KDC	50s ribosomal protein l28
FXF46_15495	ENOG4108JJ7	ABC transporter
FXF46_15510	ENOG4105IPI	Membrane
FXF46_15525	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FXF46_15530	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FXF46_15535	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FXF46_15540	ENOG41082R8	50S ribosomal protein l32
FXF46_15555	ENOG4105E0F	Histidine kinase
FXF46_15560	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FXF46_15570	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FXF46_15575	ENOG4105K5G	30S ribosomal protein S21
FXF46_15720	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
FXF46_15760	ENOG4108IND	Tetr family transcriptional regulator
FXF46_15765	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FXF46_15770	ENOG4105C26	Dehydrogenase
FXF46_15780	ENOG4105CND	Glycosyl transferase, family 2
FXF46_15820	ENOG4108Z4X	TRANSCRIPTIONal
FXF46_15830	ENOG4105D4K	integrase catalytic
FXF46_15880	ENOG4107ZSV	Receptor
FXF46_15905	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FXF46_15930	ENOG4105CIR	epoxide hydrolase
FXF46_15935	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FXF46_15945	ENOG4105DRR	Transcriptional regulator, GntR family
FXF46_15950	ENOG4108I6A	alcohol dehydrogenase
FXF46_15965	ENOG4105CSH	Transporter
FXF46_15970	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FXF46_15980	ENOG4105DND	Transcriptional regulator
FXF46_15990	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FXF46_15995	ENOG41089BK	Glutamine amido-transferase
FXF46_16070	ENOG4108YXV	Transcriptional regulator
FXF46_16155	ENOG4105DUM	transcriptional regulator, lysR family
FXF46_16160	ENOG4105VG5	Membrane
FXF46_16185	ENOG4105FA0	parb-like partition protein
FXF46_16190	ENOG4106FC9	Protein  of unknown function (DUF3018)
FXF46_16195	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
FXF46_16280	ENOG4105C4R	Atp-dependent dna helicase
FXF46_16330	ENOG4105Y2X	UPF0335 protein
FXF46_16345	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FXF46_16370	ENOG4108UUM	single-stranded DNA-binding protein
FXF46_16435	ENOG4108JJA	ABC, transporter
FXF46_16485	ENOG4107QHF	type ii secretion system protein e
FXF46_16540	ENOG4105F6A	helicase
FXF46_16545	ENOG4105D85	methylase
FXF46_16600	ENOG4105C3J	Cysteine desulfurase
FXF46_16615	ENOG4105FA0	parb-like partition protein
FXF46_16645	ENOG4108UUM	single-stranded DNA-binding protein
FXF46_16705	ENOG4108UUM	single-stranded DNA-binding protein
FXF46_16805	ENOG4107QHF	type ii secretion system protein e
FXF46_16935	ENOG4108C33	Resolvase