locus-tag	class	description
CH621_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH621_00010	COG0592	DNA-directed DNA polymerase activity
CH621_00035	COG0473	3-isopropylmalate dehydrogenase activity
CH621_00040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH621_00045	COG0758	DNA mediated transformation
CH621_00050	COG3022	response to hydroperoxide
CH621_00075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH621_00085	COG2184	nucleotidyltransferase activity
CH621_00090	COG0697	spore germination
CH621_00095	COG4145	pantothenate transmembrane transporter activity
CH621_00100	COG3924	membrane
CH621_00105	COG0439	Biotin carboxylase
CH621_00110	COG0511	ligase activity, forming carbon-carbon bonds
CH621_00120	COG1441	menaquinone biosynthetic process
CH621_00125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH621_00150	COG0728	peptidoglycan biosynthetic process
CH621_00155	COG0196	riboflavin kinase activity
CH621_00165	COG0537	adenosine 5'-monophosphoramidase activity
CH621_00170	COG5633	Lipoprotein
CH621_00175	COG1472	Belongs to the glycosyl hydrolase 3 family
CH621_00180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH621_00185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH621_00205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH621_00225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH621_00240	COG0076	glutamate decarboxylase activity
CH621_00250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH621_00255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH621_00255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH621_00265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH621_00280	COG4795	General secretion pathway protein
CH621_00285	COG2165	general secretion pathway protein
CH621_00290	COG0483	inositol monophosphate 1-phosphatase activity
CH621_00295	COG1138	Cytochrome C-type biogenesis protein
CH621_00300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH621_00305	COG4235	cytochrome complex assembly
CH621_00305	COG3088	subunit of a heme lyase
CH621_00310	COG2081	HI0933 family
CH621_00320	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CH621_00330	COG0754	glutathionylspermidine amidase activity
CH621_00335	COG0753	catalase activity
CH621_00345	COG4545	Glutaredoxin-related protein
CH621_00350	COG2852	Protein conserved in bacteria
CH621_00370	COG1466	dna polymerase III delta subunit
CH621_00375	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CH621_00385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH621_00390	COG0575	Belongs to the CDS family
CH621_00395	COG0750	zinc metalloprotease
CH621_00405	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH621_00425	COG2226	methyltransferase
CH621_00430	COG0475	glutathione-regulated potassium exporter activity
CH621_00430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH621_00435	COG0494	nUDIX hydrolase
CH621_00440	COG0653	protein targeting
CH621_00450	COG4701	Protein of unknown function (DUF721)
CH621_00455	COG0590	tRNA wobble adenosine to inosine editing
CH621_00460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CH621_00470	COG0730	response to heat
CH621_00485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH621_00490	COG1566	PFAM secretion protein HlyD family protein
CH621_00495	COG2814	Major facilitator Superfamily
CH621_00500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH621_00505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH621_00510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH621_00515	COG1309	transcriptional regulator
CH621_00545	COG0151	Belongs to the GarS family
CH621_00550	COG0138	bifunctional purine biosynthesis protein purh
CH621_00555	COG2259	Doxx family
CH621_00560	COG4232	protein-disulfide reductase activity
CH621_00565	COG0745	RESPONSE REGULATOR receiver
CH621_00570	COG1115	amino acid carrier protein
CH621_00575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH621_00580	COG0142	geranyltranstransferase activity
CH621_00595	COG0697	spore germination
CH621_00620	COG0174	glutamine synthetase
CH621_00640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH621_00655	COG3306	glycosyltransferase involved in LPS biosynthesis
CH621_00695	COG0557	exoribonuclease II activity
CH621_00700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH621_00705	COG0542	response to heat
CH621_00710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH621_00725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH621_00725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH621_00735	COG0748	coenzyme F420 binding
CH621_00740	COG0747	negative chemotaxis
CH621_00745	COG2814	Major facilitator Superfamily
CH621_00750	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH621_00760	COG3086	response to oxidative stress
CH621_00775	COG3085	chromosome segregation
CH621_00780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH621_00785	COG3084	Protein conserved in bacteria
CH621_00795	COG0402	S-adenosylhomocysteine deaminase activity
CH621_00800	COG3083	sulfuric ester hydrolase activity
CH621_00815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH621_00820	COG0745	RESPONSE REGULATOR receiver
CH621_00830	COG1053	succinate dehydrogenase
CH621_00835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH621_00840	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH621_00845	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH621_00850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH621_00860	COG0741	lytic transglycosylase activity
CH621_00865	COG2350	Protein conserved in bacteria
CH621_00870	COG1607	acyl-coa hydrolase
CH621_00885	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH621_00895	COG1879	ABC-type sugar transport system periplasmic component
CH621_00900	COG1609	Transcriptional regulator
CH621_00905	COG1085	galactose-1-phosphate uridylyltransferase
CH621_00910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CH621_00915	COG2017	converts alpha-aldose to the beta-anomer
CH621_00925	COG0006	proline dipeptidase activity
CH621_00930	COG0589	response to stress
CH621_00945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH621_00975	COG0730	response to heat
CH621_00985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH621_01020	COG0201	protein transport
CH621_01030	COG1841	ribosomal large subunit assembly
CH621_01070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH621_01105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH621_01130	COG0051	transcription antitermination factor activity, RNA binding
CH621_01135	COG0583	DNA-binding transcription factor activity
CH621_01140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CH621_01145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CH621_01150	COG2031	fatty acid transporter
CH621_01155	COG0183	Belongs to the thiolase family
CH621_01160	COG2177	Part of the ABC transporter FtsEX involved in
CH621_01165	COG2884	Cell division ATP-binding protein ftsE
CH621_01170	COG0552	protein localization to endoplasmic reticulum
CH621_01175	COG0742	ribosomal rna small subunit methyltransferase
CH621_01180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH621_01195	COG3172	ATPase kinase involved in NAD metabolism
CH621_01200	COG2129	metallophosphoesterase
CH621_01225	COG1194	a g-specific adenine glycosylase
CH621_01240	COG4942	peptidase
CH621_01245	COG2861	carbohydrate metabolic process
CH621_01270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH621_01290	COG1252	NADH dehydrogenase
CH621_01295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH621_01300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH621_01310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CH621_01315	COG0587	DNA-directed DNA polymerase activity
CH621_01320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH621_01330	COG0028	Belongs to the TPP enzyme family
CH621_01340	COG0733	neurotransmitter:sodium symporter activity
CH621_01355	COG0204	Acyl-transferase
CH621_01375	COG0514	ATP-dependent DNA helicase (RecQ)
CH621_01390	COG0019	diaminopimelate decarboxylase activity
CH621_01395	COG2197	response regulator
CH621_01435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH621_01450	COG1464	Belongs to the NlpA lipoprotein family
CH621_01455	COG1349	DNA-binding transcription factor activity
CH621_01460	COG0705	Rhomboid family
CH621_01465	COG0564	pseudouridine synthase activity
CH621_01475	COG1349	DNA-binding transcription factor activity
CH621_01480	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
CH621_01485	COG1070	Carbohydrate kinase
CH621_01495	COG0235	Class ii aldolase
CH621_01520	COG0471	metal ion transport
CH621_01525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH621_01530	COG1045	serine acetyltransferase
CH621_01540	COG3072	Adenylate cyclase
CH621_01545	COG2959	enzyme of heme biosynthesis
CH621_01550	COG3071	HemY protein
CH621_01600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH621_01605	COG1739	Uncharacterized protein family UPF0029
CH621_01620	COG0251	oxidation-reduction process
CH621_01625	COG2853	Lipoprotein
CH621_01630	COG0250	Participates in transcription elongation, termination and antitermination
CH621_01635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH621_01640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CH621_01670	COG1921	L-seryl-tRNASec selenium transferase activity
CH621_01680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH621_01685	COG0814	amino acid
CH621_01700	COG4942	peptidase
CH621_01700	COG1388	LysM domain
CH621_01710	COG1238	metal cluster binding
CH621_01725	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH621_01730	COG1047	Peptidyl-prolyl cis-trans
CH621_01735	COG0729	surface antigen
CH621_01740	COG2911	Protein conserved in bacteria
CH621_01745	COG0248	Ppx GppA phosphatase
CH621_01750	COG1187	pseudouridine synthase activity
CH621_01755	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CH621_01760	COG0584	glycerophosphoryl diester phosphodiesterase
CH621_01780	COG0584	glycerophosphoryl diester phosphodiesterase
CH621_01785	COG2271	Major facilitator Superfamily
CH621_01790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH621_01800	COG0247	lactate metabolic process
CH621_01810	COG0583	DNA-binding transcription factor activity
CH621_01815	COG2962	Rard protein
CH621_01830	COG0456	acetyltransferase
CH621_01840	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH621_01870	COG0716	FMN binding
CH621_01880	COG1494	fructose-1,6-bisphosphatase
CH621_01885	COG1132	(ABC) transporter
CH621_01890	COG4988	ABC transporter
CH621_01910	COG0551	DNA topoisomerase type I activity
CH621_01915	COG0009	L-threonylcarbamoyladenylate synthase
CH621_01930	COG2818	Glycosylase
CH621_01935	COG0463	Glycosyl transferase, family 2
CH621_01940	COG1519	Transferase
CH621_01950	COG5645	(Lipo)protein
CH621_01955	COG0210	DNA helicase
CH621_01960	COG0583	DNA-binding transcription factor activity
CH621_01965	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH621_01970	COG1285	pathogenesis
CH621_01975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH621_01980	COG2267	carboxylic ester hydrolase activity
CH621_01985	COG3005	denitrification pathway
CH621_01990	COG0243	molybdopterin cofactor binding
CH621_02030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH621_02040	COG0180	Tryptophanyl-tRNA synthetase
CH621_02045	COG3691	Protein conserved in bacteria
CH621_02050	COG1629	transport
CH621_02050	COG4771	TonB-dependent receptor
CH621_02060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH621_02065	COG0038	chloride channel
CH621_02095	COG1072	(Pantothenic acid kinase))
CH621_02100	COG3026	antisigma factor binding
CH621_02105	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH621_02110	COG1595	DNA-templated transcription, initiation
CH621_02115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH621_02125	COG0569	domain protein
CH621_02130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CH621_02130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH621_02135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CH621_02175	COG3070	regulator of competence-specific genes
CH621_02195	COG0561	phosphatase activity
CH621_02200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH621_02205	COG0549	Belongs to the carbamate kinase family
CH621_02210	COG1288	antiporter activity
CH621_02245	COG3069	C4-dicarboxylate transmembrane transporter activity
CH621_02250	COG1473	amidohydrolase
CH621_02255	COG0737	Belongs to the 5'-nucleotidase family
CH621_02260	COG0789	Transcriptional regulator
CH621_02275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH621_02295	COG2168	tRNA wobble position uridine thiolation
CH621_02300	COG2923	Belongs to the DsrF TusC family
CH621_02305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH621_02310	COG2964	Protein conserved in bacteria
CH621_02315	COG0545	Peptidyl-prolyl cis-trans isomerase
CH621_02325	COG0678	peroxiredoxin activity
CH621_02325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH621_02330	COG0583	DNA-binding transcription factor activity
CH621_02335	COG1309	transcriptional regulator
CH621_02340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH621_02345	COG2183	response to ionizing radiation
CH621_02350	COG0187	DNA topoisomerase II activity
CH621_02355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH621_02360	COG0546	phosphoglycolate phosphatase activity
CH621_02365	COG2502	aspartate--ammonia ligase
CH621_02370	COG1522	sequence-specific DNA binding
CH621_02375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH621_02380	COG1297	OPT oligopeptide transporter protein
CH621_02390	COG1218	3'(2'),5'-bisphosphate nucleotidase
CH621_02395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH621_02400	COG0363	glucosamine-6-phosphate deaminase activity
CH621_02405	COG1943	Transposase
CH621_02410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CH621_02520	COG1027	Aspartate ammonia-lyase
CH621_02525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH621_02530	COG0358	DNA primase activity
CH621_02540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CH621_02550	COG0814	amino acid
CH621_02555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH621_02560	COG3719	Belongs to the RNase T2 family
CH621_02570	COG0191	fructose-bisphosphate aldolase activity
CH621_02575	COG0859	PFAM glycosyl transferase family 9
CH621_02580	COG2364	Membrane
CH621_02585	COG1328	CTP reductase activity
CH621_02590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH621_02595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH621_02635	COG1275	C4-dicarboxylate transporter malic acid transport protein
CH621_02640	COG1720	tRNA m6t6A37 methyltransferase activity
CH621_02645	COG1575	Belongs to the MenA family. Type 1 subfamily
CH621_02660	COG1609	Transcriptional regulator
CH621_02665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH621_02670	COG1879	ABC-type sugar transport system periplasmic component
CH621_02675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH621_02690	COG1322	Protein conserved in bacteria
CH621_02695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH621_02700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH621_02715	COG3700	Belongs to the class B bacterial acid phosphatase family
CH621_02730	COG1238	metal cluster binding
CH621_02735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH621_02750	COG3312	ion transport
CH621_02795	COG0814	amino acid
CH621_02805	COG0140	phosphoribosyl-ATP diphosphatase activity
CH621_02805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH621_02830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CH621_02845	COG1561	YicC-like family, N-terminal region
CH621_02850	COG0354	folic acid binding
CH621_02855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH621_02860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH621_02865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH621_02870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH621_02875	COG2990	Protein conserved in bacteria
CH621_02880	COG3956	TIGRFAM MazG family protein
CH621_02890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH621_02895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH621_02910	COG0470	DNA polymerase III
CH621_02915	COG0084	hydrolase, TatD family'
CH621_02925	COG1253	flavin adenine dinucleotide binding
CH621_02935	COG3309	Virulence-associated protein D
CH621_02945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH621_02945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH621_02950	COG1105	Belongs to the carbohydrate kinase PfkB family
CH621_02955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH621_02955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH621_02955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH621_02965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH621_02970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH621_02980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH621_02985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH621_02990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH621_02995	COG4972	Pilus assembly protein
CH621_03000	COG3166	PFAM Fimbrial assembly family protein
CH621_03015	COG4796	Type ii and iii secretion system protein
CH621_03020	COG1040	competence protein
CH621_03035	COG3068	Protein conserved in bacteria
CH621_03040	COG0776	regulation of translation
CH621_03045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH621_03055	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH621_03065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH621_03070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH621_03080	COG0513	Belongs to the DEAD box helicase family
CH621_03090	COG0477	Major facilitator Superfamily
CH621_03100	COG0351	phosphomethylpyrimidine kinase
CH621_03110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH621_03115	COG1530	ribonuclease E activity
CH621_03120	COG0564	pseudouridine synthase activity
CH621_03125	COG1923	regulation of RNA biosynthetic process
CH621_03130	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CH621_03135	COG0739	heme binding
CH621_03140	COG1121	(ABC) transporter
CH621_03145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH621_03150	COG0825	malonyl-CoA metabolic process
CH621_03155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CH621_03170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH621_03180	COG3691	Protein conserved in bacteria
CH621_03185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH621_03190	COG0494	nUDIX hydrolase
CH621_03200	COG2850	peptidyl-arginine hydroxylation
CH621_03215	COG0012	GTP binding
CH621_03225	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH621_03230	COG0318	PFAM AMP-dependent synthetase and ligase
CH621_03235	COG3065	identical protein binding
CH621_03240	COG1214	PFAM Peptidase M22, glycoprotease
CH621_03245	COG1199	ATP-dependent helicase activity
CH621_03250	COG0824	Thioesterase
CH621_03255	COG0811	peptide transport
CH621_03260	COG0848	biopolymer transport protein
CH621_03265	COG3064	Membrane
CH621_03275	COG2885	chlorophyll binding
CH621_03355	COG3723	Recombinational DNA repair protein, rece pathway
CH621_03370	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CH621_03420	COG3561	AntA/AntB antirepressor
CH621_03500	COG0740	serine-type endopeptidase activity
CH621_03570	COG3617	BRO family, N-terminal domain
CH621_03615	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CH621_03630	COG0822	iron-sulfur transferase activity
CH621_03635	COG0316	Belongs to the HesB IscA family
CH621_03640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH621_03650	COG0443	Heat shock 70 kDa protein
CH621_03655	COG0633	Ferredoxin
CH621_03660	COG2975	iron-sulfur cluster assembly
CH621_03665	COG2976	Protein conserved in bacteria
CH621_03675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CH621_03680	COG1426	Protein conserved in bacteria
CH621_03685	COG3063	Type IV pilus biogenesis stability protein PilW
CH621_03695	COG1686	Belongs to the peptidase S11 family
CH621_03710	COG1121	(ABC) transporter
CH621_03715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH621_03720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH621_03725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CH621_03730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH621_03735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH621_03740	COG1116	anion transmembrane transporter activity
CH621_03750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH621_03755	COG2814	Major facilitator Superfamily
CH621_03765	COG3005	denitrification pathway
CH621_03770	COG3043	anaerobic respiration
CH621_03775	COG0348	domain, Protein
CH621_03780	COG0437	4 iron, 4 sulfur cluster binding
CH621_03790	COG3062	negative regulation of establishment of protein localization
CH621_03795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH621_03800	COG3171	Protein conserved in bacteria
CH621_03810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH621_03815	COG0628	permease
CH621_03820	COG0347	Belongs to the P(II) protein family
CH621_03825	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH621_03830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH621_03835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH621_03840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH621_03845	COG1381	Involved in DNA repair and RecF pathway recombination
CH621_03855	COG3061	Opacity-associated protein A
CH621_03855	COG3266	domain, Protein
CH621_03860	COG1509	lysine 2,3-aminomutase activity
CH621_03880	COG2056	Na+-H+ antiporter family
CH621_03890	COG0346	lactoylglutathione lyase activity
CH621_03910	COG1755	Isoprenylcysteine carboxyl methyltransferase
CH621_03915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CH621_03920	COG0494	nUDIX hydrolase
CH621_03950	COG4974	Belongs to the 'phage' integrase family
CH621_03955	COG2814	Major facilitator Superfamily
CH621_03960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH621_03990	COG1476	TRANSCRIPTIONal
CH621_03995	COG0582	viral genome integration into host DNA
CH621_04015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH621_04020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH621_04025	COG4535	Mg2 and Co2 transporter CorC
CH621_04030	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH621_04035	COG4969	Belongs to the N-Me-Phe pilin family
CH621_04040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH621_04045	COG1459	type II secretion system
CH621_04050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CH621_04055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH621_04065	COG0789	Transcriptional regulator
CH621_04070	COG2608	mercury ion transmembrane transporter activity
CH621_04075	COG2608	mercury ion transmembrane transporter activity
CH621_04080	COG2217	Heavy metal translocating P-type atpase
CH621_04085	COG0814	amino acid
CH621_04090	COG1760	l-serine dehydratase
CH621_04095	COG0814	amino acid
CH621_04100	COG0436	Aminotransferase
CH621_04110	COG1169	isochorismate synthase
CH621_04120	COG2267	carboxylic ester hydrolase activity
CH621_04125	COG0477	Major facilitator Superfamily
CH621_04130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH621_04135	COG2258	MOSC domain
CH621_04150	COG1368	sulfuric ester hydrolase activity
CH621_04195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH621_04205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH621_04225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH621_04230	COG3210	domain, Protein
CH621_04245	COG0859	PFAM glycosyl transferase family 9
CH621_04250	COG3642	lipopolysaccharide core region biosynthetic process
CH621_04255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH621_04265	COG1442	glycosyl transferase family 8
CH621_04275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH621_04280	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH621_04290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH621_04295	COG0811	peptide transport
CH621_04300	COG0848	biopolymer transport protein
CH621_04305	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH621_04310	COG0629	single-stranded DNA binding
CH621_04315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH621_04325	COG0641	radical SAM
CH621_04335	COG0343	queuine tRNA-ribosyltransferase activity
CH621_04340	COG3945	hemerythrin HHE cation binding domain
CH621_04345	COG0425	Belongs to the sulfur carrier protein TusA family
CH621_04350	COG1862	Preprotein translocase
CH621_04355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH621_04360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH621_04370	COG1393	Belongs to the ArsC family
CH621_04375	COG3036	rescue of stalled ribosome
CH621_04390	COG0513	Belongs to the DEAD box helicase family
CH621_04395	COG4785	May be involved in cell division
CH621_04410	COG2731	YhcH YjgK YiaL family protein
CH621_04415	COG1114	Component of the transport system for branched-chain amino acids
CH621_04425	COG1522	sequence-specific DNA binding
CH621_04430	COG2962	Rard protein
CH621_04440	COG0516	GMP reductase activity
CH621_04440	COG0517	IMP dehydrogenase activity
CH621_04445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CH621_04445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CH621_04470	COG1573	uracil-dna glycosylase
CH621_04480	COG3059	membrane
CH621_04500	COG0732	type I restriction modification DNA specificity domain
CH621_04510	COG0339	signal peptide processing
CH621_04515	COG2832	Protein of unknown function (DUF454)
CH621_04520	COG4166	transmembrane transport
CH621_04530	COG0671	phosphoesterase, PA-phosphatase related
CH621_04535	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CH621_04550	COG0737	Belongs to the 5'-nucleotidase family
CH621_04585	COG1560	Kdo2-lipid A biosynthetic process
CH621_04590	COG0730	response to heat
CH621_04595	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH621_04605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CH621_04605	COG3264	Mechanosensitive ion channel
CH621_04610	COG0318	PFAM AMP-dependent synthetase and ligase
CH621_04615	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH621_04620	COG0596	Alpha beta hydrolase
CH621_04625	COG0716	FMN binding
CH621_04630	COG0735	belongs to the Fur family
CH621_04635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CH621_04640	COG0805	protein transport
CH621_04655	COG0789	Transcriptional regulator
CH621_04660	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CH621_04665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CH621_04670	COG1115	amino acid carrier protein
CH621_04680	COG2116	formate transmembrane transporter activity
CH621_04685	COG1882	Formate acetyltransferase
CH621_04690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH621_04700	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH621_04705	COG0564	pseudouridine synthase activity
CH621_04720	COG2991	Protein conserved in bacteria
CH621_04725	COG1477	protein flavinylation
CH621_04745	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH621_04765	COG3056	Lipoprotein
CH621_04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH621_04775	COG0688	phosphatidylethanolamine metabolic process
CH621_04780	COG1399	metal-binding, possibly nucleic acid-binding protein
CH621_04785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH621_04800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH621_04805	COG1028	Short-chain dehydrogenase reductase Sdr
CH621_04815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH621_04820	COG2091	lysine biosynthetic process via aminoadipic acid
CH621_04825	COG0330	HflC and HflK could
CH621_04830	COG0330	HflC and HflK could
CH621_04835	COG2020	methyltransferase activity
CH621_04845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH621_04845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH621_04855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CH621_04865	COG1737	Transcriptional regulator
CH621_04870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH621_04880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH621_04895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH621_04910	COG1160	GTP binding
CH621_04915	COG2814	Major facilitator Superfamily
CH621_04935	COG2252	PERMEase
CH621_04940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH621_04960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH621_04965	COG0626	cystathionine gamma-synthase activity
CH621_04975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH621_04980	COG5413	integral membrane protein
CH621_04985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH621_04990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH621_04995	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH621_05055	COG0625	glutathione transferase activity
CH621_05065	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH621_05070	COG3610	response to peptide
CH621_05075	COG3610	response to peptide
CH621_05080	COG4536	flavin adenine dinucleotide binding
CH621_05085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH621_05110	COG3423	Transcriptional regulator
CH621_05115	COG2801	Transposase and inactivated derivatives
CH621_05120	COG2842	Transposition protein
CH621_05130	COG4396	Host-nuclease inhibitor protein Gam
CH621_05150	COG4382	Mu-like prophage protein Gp16
CH621_05165	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH621_05325	COG4416	COG NOG18757 non supervised orthologous group
CH621_05330	COG3392	D12 class N6 adenine-specific DNA methyltransferase
CH621_05350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CH621_05355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH621_05360	COG0326	Molecular chaperone. Has ATPase activity
CH621_05365	COG1393	Belongs to the ArsC family
CH621_05375	COG1876	peptidase activity
CH621_05380	COG3842	ATPase activity
CH621_05385	COG1178	ABC-type Fe3 transport system permease component
CH621_05390	COG1840	ABC-type Fe3 transport system, periplasmic component
CH621_05395	COG4797	methyltransferase
CH621_05395	COG4797	methyltransferase
CH621_05400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH621_05405	COG0527	aspartate kinase activity
CH621_05405	COG0460	homoserine dehydrogenase
CH621_05415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CH621_05440	COG0626	cystathionine gamma-synthase activity
CH621_05445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH621_05450	COG3118	belongs to the thioredoxin family
CH621_05460	COG0084	hydrolase, TatD family'
CH621_05465	COG3692	DNA binding
CH621_05470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH621_05480	COG1946	Acyl-CoA thioesterase
CH621_05485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CH621_05485	COG1328	CTP reductase activity
CH621_05490	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CH621_05495	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CH621_05500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH621_05510	COG0497	DNA recombination
CH621_05515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CH621_05530	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH621_05530	COG1388	LysM domain
CH621_05535	COG0802	atpase or kinase
CH621_05540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH621_05545	COG0617	tRNA 3'-terminal CCA addition
CH621_05550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH621_05555	COG2333	competence protein COMEC
CH621_05555	COG0658	competence protein
CH621_05560	COG1132	(ABC) transporter
CH621_05565	COG1663	tetraacyldisaccharide 4'-kinase activity
CH621_05580	COG0322	excinuclease ABC activity
CH621_05585	COG0861	Integral membrane protein TerC family
CH621_05595	COG2186	Transcriptional regulator
CH621_05600	COG1063	alcohol dehydrogenase
CH621_05605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH621_05610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH621_05615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH621_05620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH621_05625	COG1028	Short-chain dehydrogenase reductase Sdr
CH621_05630	COG0800	Aldolase
CH621_05635	COG2824	Alkylphosphonate utilization operon protein PhnA
CH621_05640	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH621_05650	COG0670	Belongs to the BI1 family
CH621_05660	COG0564	pseudouridine synthase activity
CH621_05665	COG0708	Exodeoxyribonuclease III
CH621_05670	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH621_05675	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH621_05680	COG1792	Involved in formation and maintenance of cell shape
CH621_05685	COG1077	Cell shape determining protein MreB Mrl
CH621_05690	COG4178	(ABC) transporter
CH621_05695	COG2985	domain, Protein
CH621_05700	COG0799	negative regulation of ribosome biogenesis
CH621_05710	COG0768	penicillin binding
CH621_05715	COG0772	Belongs to the SEDS family
CH621_05720	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH621_05720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH621_05725	COG1686	Belongs to the peptidase S11 family
CH621_05730	COG2921	Belongs to the UPF0250 family
CH621_05745	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CH621_05755	COG2301	Belongs to the HpcH HpaI aldolase family
CH621_05760	COG3051	citrate lyase alpha subunit
CH621_05765	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CH621_05765	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CH621_05770	COG0471	metal ion transport
CH621_05795	COG0681	Belongs to the peptidase S26 family
CH621_05800	COG0571	ribonuclease III activity
CH621_05815	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH621_05820	COG0456	acetyltransferase
CH621_05830	COG2864	formate dehydrogenase
CH621_05835	COG0437	4 iron, 4 sulfur cluster binding
CH621_05850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CH621_05860	COG0561	phosphatase activity
CH621_05865	COG1022	Amp-dependent synthetase and ligase
CH621_05870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH621_05885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH621_05890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH621_05930	COG0583	DNA-binding transcription factor activity
CH621_05935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH621_05940	COG1687	branched-chain amino acid
CH621_05955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CH621_05965	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH621_05970	COG1984	allophanate hydrolase subunit 2
CH621_05980	COG1914	H( )-stimulated, divalent metal cation uptake system
CH621_05995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH621_06000	COG3112	Uncharacterised protein family (UPF0231)
CH621_06010	COG0024	Methionine aminopeptidase
CH621_06020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH621_06040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH621_06045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH621_06050	COG2190	(PTS) system
CH621_06060	COG3111	PFAM Bacterial OB fold (BOF) protein
CH621_06070	COG0642	Histidine kinase
CH621_06075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH621_06085	COG0795	lipopolysaccharide-transporting ATPase activity
CH621_06090	COG0795	lipopolysaccharide-transporting ATPase activity
CH621_06100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CH621_06105	COG2244	polysaccharide biosynthetic process
CH621_06115	COG0438	transferase activity, transferring glycosyl groups
CH621_06120	COG3306	glycosyltransferase involved in LPS biosynthesis
CH621_06125	COG1216	Glycosyl transferase, family 2
CH621_06130	COG1216	Glycosyl transferase, family 2
CH621_06135	COG2005	Transcriptional regulator
CH621_06140	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH621_06145	COG4149	molybdate abc transporter
CH621_06155	COG0733	neurotransmitter:sodium symporter activity
CH621_06160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH621_06180	COG4656	Part of a membrane complex involved in electron transport
CH621_06180	COG4656	Part of a membrane complex involved in electron transport
CH621_06190	COG4657	Part of a membrane complex involved in electron transport
CH621_06200	COG0616	signal peptide processing
CH621_06210	COG1289	transmembrane transporter activity
CH621_06215	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH621_06230	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH621_06235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH621_06235	COG0517	IMP dehydrogenase activity
CH621_06245	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CH621_06260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH621_06265	COG0314	molybdopterin synthase activity
CH621_06270	COG3008	intermembrane lipid transfer
CH621_06275	COG2995	paraquat-inducible protein a
CH621_06285	COG0793	Belongs to the peptidase S41A family
CH621_06290	COG2989	Protein conserved in bacteria
CH621_06295	COG3108	Peptidase M15
CH621_06300	COG0084	hydrolase, TatD family'
CH621_06305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH621_06310	COG0567	Dehydrogenase, E1 component
CH621_06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH621_06320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH621_06325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH621_06330	COG2823	Periplasmic or secreted lipoprotein
CH621_06335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CH621_06345	COG3107	peptidoglycan biosynthetic process
CH621_06350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH621_06360	COG0791	NLP P60 protein
CH621_06380	COG0277	FAD linked oxidase domain protein
CH621_06395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CH621_06400	COG0539	negative regulation of cytoplasmic translation
CH621_06410	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH621_06415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH621_06425	COG0023	Translation Initiation Factor
CH621_06430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH621_06435	COG2233	PERMEase
CH621_06445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH621_06455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH621_06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH621_06465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH621_06475	COG5339	Protein conserved in bacteria
CH621_06495	COG2860	membrane
CH621_06505	COG2814	Major facilitator Superfamily
CH621_06510	COG1187	pseudouridine synthase activity
CH621_06515	COG3955	Domain of unknown function (DUF1919)
CH621_06520	COG0281	malic enzyme
CH621_06520	COG0280	phosphate acetyltransferase
CH621_06525	COG1368	sulfuric ester hydrolase activity
CH621_06540	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH621_06545	COG3683	transport system, periplasmic component
CH621_06550	COG3549	Plasmid maintenance system killer
CH621_06555	COG3093	addiction module antidote protein HigA
CH621_06560	COG0488	(ABC) transporter
CH621_06565	COG3094	Invasion gene expression up-regulator, SirB
CH621_06570	COG1444	tRNA N-acetyltransferase activity
CH621_06575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH621_06580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH621_06590	COG0285	dihydrofolate synthase activity
CH621_06595	COG2949	membrane
CH621_06605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH621_06615	COG1944	ATP diphosphatase activity
CH621_06640	COG0500	methyltransferase
CH621_06645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH621_06660	COG0489	protein tyrosine kinase activity
CH621_06665	COG0778	Nitroreductase
CH621_06670	COG1083	cytidylyl-transferase
CH621_06720	COG3772	lysozyme
CH621_06815	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH621_06870	COG0195	Participates in both transcription termination and antitermination
CH621_06875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH621_06880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CH621_06890	COG0732	type I restriction modification DNA specificity domain
CH621_06895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CH621_06910	COG0287	Prephenate dehydrogenase
CH621_06910	COG1605	Chorismate mutase
CH621_06920	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CH621_06925	COG2166	iron-sulfur cluster assembly
CH621_06930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH621_06935	COG1525	nuclease
CH621_06945	COG1346	cytolysis
CH621_06960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH621_06965	COG1177	transmembrane transport
CH621_06970	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH621_06975	COG3842	ATPase activity
CH621_06985	COG0783	Belongs to the Dps family
CH621_07000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH621_07005	COG1530	ribonuclease E activity
CH621_07020	COG1640	4-alpha-glucanotransferase
CH621_07030	COG1523	belongs to the glycosyl hydrolase 13 family
CH621_07045	COG0058	SHG alpha-glucan phosphorylase activity
CH621_07050	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH621_07055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH621_07060	COG0583	DNA-binding transcription factor activity
CH621_07065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH621_07075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CH621_07080	COG0612	Peptidase, M16
CH621_07090	COG3585	molybdate ion transport
CH621_07095	COG2920	part of a sulfur-relay system
CH621_07100	COG0037	tRNA processing
CH621_07105	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH621_07120	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH621_07130	COG3586	endonuclease activity
CH621_07135	COG0697	spore germination
CH621_07140	COG2925	Exonuclease
CH621_07145	COG5002	protein histidine kinase activity
CH621_07150	COG0745	RESPONSE REGULATOR receiver
CH621_07160	COG0581	inorganic phosphate transmembrane transporter activity
CH621_07165	COG0573	inorganic phosphate transmembrane transporter activity
CH621_07170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH621_07175	COG1528	Iron-storage protein
CH621_07180	COG1528	Iron-storage protein
CH621_07190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CH621_07195	COG0512	Glutamine amidotransferase of anthranilate synthase
CH621_07200	COG1942	4-Oxalocrotonate Tautomerase
CH621_07210	COG0135	phosphoribosylanthranilate isomerase activity
CH621_07210	COG0134	indole-3-glycerol-phosphate synthase activity
CH621_07215	COG0298	carbon dioxide binding
CH621_07220	COG0525	valine-tRNA ligase activity
CH621_07240	COG4185	zeta toxin
CH621_07245	COG2927	DNA polymerase III (CHI subunit)
CH621_07250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH621_07255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH621_07260	COG1442	glycosyl transferase family 8
CH621_07265	COG0114	fumarate hydratase activity
CH621_07270	COG2268	Band 7 protein
CH621_07275	COG0613	PHP domain protein
CH621_07285	COG3566	protein conserved in bacteria
CH621_07290	COG2369	cell adhesion
CH621_07295	COG3567	Phage-associated protein, HI1409 family
CH621_07300	COG1783	phage Terminase large subunit
CH621_07305	COG3728	DNA packaging
CH621_07325	COG3179	chitinase
CH621_07335	COG3617	BRO family, N-terminal domain
CH621_07440	COG3561	AntA/AntB antirepressor
CH621_07445	COG0582	viral genome integration into host DNA
CH621_07455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH621_07460	COG0589	response to stress
CH621_07465	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
CH621_07470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH621_07480	COG4221	oxidoreductase activity
CH621_07495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH621_07500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH621_07505	COG1278	Cold shock
CH621_07515	COG0564	pseudouridine synthase activity
CH621_07520	COG3098	single-species biofilm formation
CH621_07535	COG0142	geranyltranstransferase activity
CH621_07545	COG2969	positive regulation of protein catabolic process
CH621_07550	COG0625	glutathione transferase activity
CH621_07565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CH621_07570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH621_07575	COG3100	YcgL domain-containing protein
CH621_07580	COG0302	gtp cyclohydrolase
CH621_07585	COG0303	'Molybdopterin
CH621_07590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH621_07595	COG3099	Belongs to the UPF0263 family
CH621_07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH621_07605	COG0785	Cytochrome C biogenesis protein
CH621_07610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH621_07610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH621_07625	COG1595	DNA-templated transcription, initiation
CH621_07645	COG1538	Outer membrane efflux protein
CH621_07655	COG2062	phosphohistidine phosphatase, SixA
CH621_07665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH621_07670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH621_07675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CH621_07680	COG1534	Rna-binding protein
CH621_07685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH621_07690	COG2027	D-alanyl-D-alanine carboxypeptidase
CH621_07710	COG0515	serine threonine protein kinase
CH621_07720	COG1067	ATP-dependent peptidase activity
CH621_07730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH621_07735	COG1074	ATP-dependent DNA helicase activity
CH621_07740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CH621_07745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CH621_07755	COG0676	glucose-6-phosphate 1-epimerase activity
CH621_07760	COG3119	arylsulfatase activity
CH621_07765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH621_07775	COG0631	protein serine/threonine phosphatase activity
CH621_07780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH621_07785	COG1674	ftsk spoiiie
CH621_07795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH621_07810	COG0791	NLP P60 protein
CH621_07835	COG0633	Ferredoxin
CH621_07845	COG1280	lysine exporter protein (LysE YggA)
CH621_07850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH621_07855	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH621_07875	COG0288	reversible hydration of carbon dioxide
CH621_07910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CH621_07910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CH621_07915	COG1560	Kdo2-lipid A biosynthetic process
CH621_07920	COG0187	DNA topoisomerase II activity
CH621_07925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH621_07930	COG0786	glutamate:sodium symporter activity
CH621_07940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH621_07945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH621_07950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH621_07950	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CH621_07960	COG0510	thiamine kinase activity
CH621_07965	COG0697	spore germination
CH621_07970	COG4750	Nucleotidyl transferase
CH621_07975	COG3475	LICD family
CH621_07980	COG0616	signal peptide processing
CH621_07985	COG0778	Nitroreductase
CH621_07990	COG3381	protein complex oligomerization
CH621_07995	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH621_08005	COG2932	Transcriptional regulator
CH621_08010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH621_08015	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH621_08025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH621_08030	COG0500	methyltransferase
CH621_08035	COG2830	Protein of unknown function (DUF452)
CH621_08045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CH621_08050	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH621_08055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH621_08065	COG2912	Transglutaminase-like superfamily
CH621_08070	COG2890	protein-(glutamine-N5) methyltransferase activity
CH621_08075	COG1714	RDD family
CH621_08095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CH621_08100	COG3101	peptidyl-lysine hydroxylation
CH621_08105	COG2369	cell adhesion
CH621_08110	COG4383	Mu-like prophage protein gp29
CH621_08130	COG0469	pyruvate kinase activity
CH621_08135	COG0305	Participates in initiation and elongation during chromosome replication
CH621_08140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH621_08155	COG1216	Glycosyl transferase, family 2
CH621_08160	COG3133	Outer membrane lipoprotein
CH621_08170	COG3102	Protein conserved in bacteria
CH621_08180	COG0440	acetolactate synthase activity
CH621_08185	COG0028	Belongs to the TPP enzyme family
CH621_08195	COG1757	Na H antiporter
CH621_08200	COG2916	Histone family protein nucleoid-structuring protein H-NS
CH621_08205	COG0788	formyltetrahydrofolate deformylase activity
CH621_08215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH621_08225	COG1674	ftsk spoiiie
CH621_08230	COG1522	sequence-specific DNA binding
CH621_08235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CH621_08240	COG3025	triphosphatase activity
CH621_08255	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH621_08290	COG3219	Protein conserved in bacteria
CH621_08295	COG3220	belongs to the UPF0276 family
CH621_08305	COG2259	Doxx family
CH621_08310	COG1392	Phosphate transport regulator
CH621_08315	COG0306	phosphate transporter
CH621_08320	COG4991	sh3 domain protein
CH621_08330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CH621_08340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH621_08355	COG0534	Mate efflux family protein
CH621_08360	COG0307	riboflavin synthase, alpha
CH621_08365	COG0308	aminopeptidase N
CH621_08380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH621_08385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH621_08390	COG1448	Aminotransferase
CH621_08395	COG1122	ATPase activity
CH621_08400	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CH621_08405	COG0310	cobalt ion transport
CH621_08410	COG0310	cobalt ion transport
CH621_08415	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
CH621_08420	COG0789	Transcriptional regulator
CH621_08425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CH621_08435	COG0251	oxidation-reduction process
CH621_08440	COG3105	Protein conserved in bacteria
CH621_08475	COG0527	aspartate kinase activity
CH621_08500	COG3106	COG3106 Predicted ATPase
CH621_08505	COG4166	transmembrane transport
CH621_08510	COG4168	peptide transport system, permease
CH621_08515	COG4171	peptide transport system, permease
CH621_08520	COG4172	Belongs to the ABC transporter superfamily
CH621_08525	COG4172	Belongs to the ABC transporter superfamily
CH621_08530	COG2855	membrane
CH621_08550	COG1620	l-lactate permease
CH621_08555	COG4206	TonB-dependent receptor
CH621_08555	COG1629	transport
CH621_08565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH621_08570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH621_08575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH621_08590	COG0039	L-malate dehydrogenase activity
CH621_08600	COG1090	epimerase
CH621_08605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH621_08610	COG1286	toxin biosynthetic process
CH621_08615	COG3092	negative regulation of chromosome organization
CH621_08625	COG0857	belongs to the CobB CobQ family
CH621_08625	COG0280	phosphate acetyltransferase
CH621_08630	COG2840	Smr protein MutS2
CH621_08635	COG2890	protein-(glutamine-N5) methyltransferase activity
CH621_08640	COG0583	DNA-binding transcription factor activity
CH621_08645	COG1187	pseudouridine synthase activity
CH621_08650	COG0009	L-threonylcarbamoyladenylate synthase
CH621_08655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH621_08665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CH621_08670	COG0583	DNA-binding transcription factor activity
CH621_08675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH621_08690	COG0720	synthase
CH621_08695	COG0602	queuosine metabolic process
CH621_08705	COG0210	DNA helicase
CH621_08710	COG0601	transmembrane transport
CH621_08715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH621_08720	COG0444	Belongs to the ABC transporter superfamily
CH621_08725	COG4608	Belongs to the ABC transporter superfamily
CH621_08730	COG1793	dna ligase
CH621_08740	COG1126	abc transporter atp-binding protein
CH621_08745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH621_08750	COG4215	(ABC) transporter
CH621_08755	COG4160	amino acid transport
CH621_08765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH621_08770	COG3091	SprT-like family
CH621_08780	COG0512	Glutamine amidotransferase of anthranilate synthase
CH621_08785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CH621_08790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH621_08795	COG2926	Belongs to the UPF0265 family
CH621_08800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CH621_08815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH621_08815	COG2885	chlorophyll binding
CH621_08820	COG0277	FAD linked oxidase domain protein
CH621_08820	COG0247	lactate metabolic process
CH621_08825	COG2050	protein possibly involved in aromatic compounds catabolism
CH621_08830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CH621_08835	COG3118	belongs to the thioredoxin family
CH621_08840	COG0492	ferredoxin-NADP+ reductase activity
CH621_08845	COG4988	ABC transporter
CH621_08850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH621_08860	COG0602	queuosine metabolic process
CH621_08865	COG1823	symporter activity
CH621_08870	COG1280	lysine exporter protein (LysE YggA)
CH621_08875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH621_08880	COG0312	modulator of DNA gyrase
CH621_08885	COG3028	Belongs to the UPF0307 family
CH621_08890	COG3117	lipopolysaccharide transmembrane transporter activity
CH621_08895	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH621_08900	COG1137	ATPase activity
CH621_08905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH621_08910	COG1660	Displays ATPase and GTPase activities
CH621_08915	COG0077	Prephenate dehydratase
CH621_08915	COG1605	Chorismate mutase
CH621_08925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH621_08930	COG0849	cell division
CH621_08935	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH621_08955	COG0772	Belongs to the SEDS family
CH621_08970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH621_08980	COG0768	penicillin binding
CH621_08985	COG3116	cell division
CH621_09000	COG1966	Carbon starvation protein
CH621_09015	COG4166	transmembrane transport
CH621_09020	COG0601	transmembrane transport
CH621_09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH621_09030	COG0444	Belongs to the ABC transporter superfamily
CH621_09035	COG4608	Belongs to the ABC transporter superfamily
CH621_09040	COG2990	Protein conserved in bacteria
CH621_09050	COG0606	chelatase, subunit chli
CH621_09060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH621_09070	COG1070	Carbohydrate kinase
CH621_09080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH621_09085	COG1757	Na H antiporter
CH621_09090	COG2207	Transcriptional regulator
CH621_09090	COG1609	Transcriptional regulator
CH621_09095	COG0859	PFAM glycosyl transferase family 9
CH621_09100	COG2814	Major facilitator Superfamily
CH621_09105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH621_09145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH621_09150	COG1138	Cytochrome C-type biogenesis protein
CH621_09160	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH621_09165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH621_09170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH621_09180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH621_09185	COG1127	ABC transporter
CH621_09190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH621_09195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH621_09200	COG2854	intermembrane phospholipid transfer
CH621_09205	COG3113	response to antibiotic
CH621_09210	COG5007	Belongs to the BolA IbaG family
CH621_09220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH621_09225	COG0765	amino acid transport
CH621_09230	COG1126	abc transporter atp-binding protein
CH621_09235	COG3201	nicotinamide mononucleotide transporter
CH621_09250	COG1271	oxidase subunit
CH621_09255	COG1294	oxidase, subunit
CH621_09265	COG2363	Small membrane protein
CH621_09270	COG1643	Atp-dependent helicase
CH621_09280	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CH621_09285	COG0437	4 iron, 4 sulfur cluster binding
CH621_09290	COG3301	Polysulphide reductase, NrfD
CH621_09300	COG2194	sulfuric ester hydrolase activity
CH621_09305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH621_09330	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CH621_09335	COG3421	Type III restriction
CH621_09340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH621_09345	COG4977	sequence-specific DNA binding
CH621_09345	COG1917	Cupin 2, conserved barrel domain protein
CH621_09350	COG1132	(ABC) transporter
CH621_09355	COG2608	mercury ion transmembrane transporter activity
CH621_09365	COG1305	Transglutaminase-like
CH621_09370	COG0243	molybdopterin cofactor binding
CH621_09375	COG0437	4 iron, 4 sulfur cluster binding
CH621_09380	COG3302	dmso reductase anchor subunit
CH621_09385	COG3381	protein complex oligomerization
CH621_09390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH621_09390	COG2221	Nitrite and sulphite reductase 4Fe-4S
CH621_09410	COG1373	ATPase (AAA superfamily
CH621_09415	COG0121	glutamine amidotransferase
CH621_09420	COG0762	integral membrane protein
CH621_09430	COG1666	GTP binding
CH621_09435	COG0560	Phosphoserine phosphatase
CH621_09440	COG1414	Transcriptional regulator
CH621_09445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CH621_09450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH621_09455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH621_09460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH621_09465	COG1070	Carbohydrate kinase
CH621_09470	COG3623	hexulose-6-phosphate isomerase
CH621_09475	COG0235	Class ii aldolase
CH621_09480	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CH621_09485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH621_09495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH621_09500	COG1178	ABC-type Fe3 transport system permease component
CH621_09505	COG4143	(ABC) transporter
CH621_09510	COG1555	photosystem II stabilization
CH621_09525	COG2194	sulfuric ester hydrolase activity
CH621_09530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH621_09535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CH621_09555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH621_09570	COG1629	transport
CH621_09570	COG4771	TonB-dependent receptor