locus-tag	class	description
EI420_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EI420_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EI420_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EI420_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI420_00025	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EI420_00030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EI420_00035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
EI420_00040	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
EI420_00045	ENOG4105XA0	heptosyltransferase ii
EI420_00050	ENOG4107RES	phosphoglycerol transferase I
EI420_00060	ENOG4105CPK	Glycosyl transferase (Group 1
EI420_00070	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
EI420_00080	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EI420_00085	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EI420_00090	ENOG4105E66	phosphoriboisomerase A
EI420_00095	ENOG4105C7B	Threonine dehydratase
EI420_00100	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EI420_00110	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
EI420_00120	ENOG4107RAQ	aminopeptidase
EI420_00125	ENOG4105D0A	hydroxylase
EI420_00130	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EI420_00135	ENOG4105CN1	protease
EI420_00140	ENOG41063SB	peptidase
EI420_00145	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EI420_00150	ENOG4107YZP	Rhodanese domain protein
EI420_00155	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EI420_00160	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EI420_00165	ENOG4105QNR	S1 RNA binding domain protein
EI420_00170	ENOG4105D7Z	glutathione synthase
EI420_00175	ENOG4108UJU	UPF0301 protein
EI420_00180	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EI420_00185	ENOG4105CXT	aspartate transcarbamylase
EI420_00220	ENOG4108ZJT	translation initiation factor, Sui1
EI420_00225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EI420_00235	ENOG4105D2N	Aldolase
EI420_00240	ENOG4105BZA	Phosphoglycerate kinase
EI420_00245	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EI420_00250	ENOG41067MG	lrgb family
EI420_00260	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EI420_00265	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EI420_00275	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
EI420_00285	ENOG4105SYT	Methylenetetrahydrofolate reductase
EI420_00305	ENOG4105DGW	oligopeptidase A
EI420_00310	ENOG4105C8J	)-transporter
EI420_00315	ENOG4108Z0R	Transferase
EI420_00325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_00330	ENOG4105CQZ	Histidine kinase
EI420_00335	ENOG41073TP	transcriptional regulator
EI420_00340	ENOG4105DMF	Dehydrogenase
EI420_00380	ENOG4105M9M	anti-sigma28 factor FlgM
EI420_00385	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
EI420_00390	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
EI420_00395	ENOG4108ZC9	flagellar basal-body rod protein flgc
EI420_00400	ENOG4105W00	Flagellar hook capping protein
EI420_00405	ENOG4105BZE	flagellar hook protein, FlgE
EI420_00410	ENOG4108KPB	Flagellar basal-body rod protein FlgF
EI420_00415	ENOG4105CGA	flagellar basal-body rod protein FlgG
EI420_00425	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EI420_00430	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
EI420_00435	ENOG4105E1Q	flagellar hook-associated protein
EI420_00440	ENOG4105DTJ	flagellar hook-associated protein
EI420_00445	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EI420_00450	ENOG4105VS8	Flagellar biosynthetic protein fliq
EI420_00455	ENOG4105CN7	Flagellar biosynthetic protein FliP
EI420_00460	ENOG4105K0P	flagellar biosynthesis protein
EI420_00465	ENOG4105DD5	Flagellar motor switch protein
EI420_00470	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EI420_00475	ENOG4107ZI8	flagellar basal body-associated protein flil
EI420_00485	ENOG4105GSA	Flagellar export protein flij
EI420_00490	ENOG4108JIR	Flagellum-specific ATP synthase
EI420_00500	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EI420_00505	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EI420_00510	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
EI420_00515	ENOG41063QE	flagellar protein FlaG
EI420_00525	ENOG4105MQ3	flagellar protein FliS
EI420_00545	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
EI420_00550	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
EI420_00555	ENOG4107RD7	Flagellar Motor Protein, MotA
EI420_00560	ENOG4105ER2	Ompa motb domain protein
EI420_00565	ENOG4105CBS	Chea signal transduction histidine kinase
EI420_00570	ENOG4108V3W	Chemotaxis protein, CheW
EI420_00575	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_00580	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EI420_00580	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EI420_00585	ENOG4105BZU	Histidine kinase
EI420_00590	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EI420_00595	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_00600	ENOG4108VYJ	response regulator receiver protein
EI420_00605	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
EI420_00610	ENOG4105D00	flagellar biosynthetic protein flhB
EI420_00615	ENOG4105D7B	Flagellar biosynthesis protein flha
EI420_00620	ENOG4105FZW	flagellar biosynthesis regulator FlhF
EI420_00635	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI420_00640	ENOG4107R0U	MotA TolQ exbB proton channel
EI420_00645	ENOG4106VK6	Flagellar motor protein
EI420_00650	ENOG4105BZU	Histidine kinase
EI420_00670	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EI420_00675	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EI420_00680	ENOG4107RDB	Major Facilitator
EI420_00685	ENOG4108UUM	single-stranded DNA-binding protein
EI420_00705	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EI420_00710	ENOG4105BZU	Histidine kinase
EI420_00735	ENOG4107FW0	short-chain dehydrogenase reductase
EI420_00745	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EI420_00750	ENOG4108XDN	Transcriptional regulator
EI420_00755	ENOG4108QDE	fad dependent oxidoreductase
EI420_00760	ENOG4105ECP	epimerase
EI420_00765	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
EI420_00790	ENOG4105C32	Amino acid ABC transporter (Permease)
EI420_00795	ENOG4108IV0	ABC, transporter
EI420_00800	ENOG4105C0Z	ABC transporter
EI420_00805	ENOG4105C8J	)-transporter
EI420_00815	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EI420_00820	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EI420_00845	ENOG4105PM1	preprotein translocase subunit SecE
EI420_00850	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EI420_00855	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EI420_00860	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EI420_00865	ENOG4108VZM	50s ribosomal protein L10
EI420_00870	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EI420_00875	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI420_00880	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI420_00885	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EI420_00890	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EI420_00895	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EI420_00900	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EI420_00905	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EI420_00910	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EI420_00915	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EI420_00920	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EI420_00925	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI420_00930	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EI420_00935	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EI420_00940	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EI420_00945	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EI420_00950	ENOG41083MP	50s ribosomal protein l29
EI420_00955	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EI420_00960	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EI420_00965	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EI420_00970	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI420_00975	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EI420_00980	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EI420_00985	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EI420_00990	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EI420_00995	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EI420_01000	ENOG4105VPB	50S ribosomal protein L30
EI420_01005	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EI420_01010	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EI420_01015	ENOG41067V7	50S ribosomal protein L36
EI420_01020	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI420_01025	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EI420_01030	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EI420_01035	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EI420_01040	ENOG4108ZT0	50S ribosomal protein l17
EI420_01045	ENOG4105DZ1	carboxypeptidase
EI420_01050	ENOG4105DFI	Membrane
EI420_01055	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EI420_01065	ENOG4105CC0	LysR family Transcriptional regulator
EI420_01070	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EI420_01075	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
EI420_01085	ENOG4107XDR	Lactoylglutathione lyase
EI420_01105	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_01110	ENOG4105DSE	periplasmic solute binding protein
EI420_01115	ENOG4105CC5	ABC transporter
EI420_01120	ENOG4105DIK	(ABC) transporter
EI420_01135	ENOG4105D64	Mechanosensitive ion channel
EI420_01150	ENOG4105C5F	glutamine synthetase
EI420_01155	ENOG4105CUX	Signal transduction histidine kinase
EI420_01160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_01185	ENOG410841Q	phosphoesterase PA-phosphatase related protein
EI420_01195	ENOG4105QMY	Porin Gram-negative type
EI420_01200	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
EI420_01205	ENOG4105GRZ	Ycii-related protein
EI420_01210	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
EI420_01215	ENOG4105CHP	RNA polymerase
EI420_01225	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
EI420_01265	ENOG4105DFD	Na H antiporter
EI420_01270	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_01275	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EI420_01285	ENOG4107QP7	CoA-transferase subunit A
EI420_01290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EI420_01295	ENOG4107RSM	transcriptional regulator
EI420_01305	ENOG4105F2V	VRR-NUC domain-containing protein
EI420_01320	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
EI420_01340	ENOG4105EAH	synthase
EI420_01345	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EI420_01350	ENOG4105K46	50S ribosomal protein l27
EI420_01355	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI420_01360	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EI420_01380	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI420_01385	ENOG4105E0F	Histidine kinase
EI420_01395	ENOG4105BZU	Histidine kinase
EI420_01405	ENOG4108QBX	(LipO)protein
EI420_01435	ENOG4105BZU	Histidine kinase
EI420_01440	ENOG4105DN9	Na H antiporter
EI420_01460	ENOG4105DUM	transcriptional regulator, lysR family
EI420_01465	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EI420_01475	ENOG4105DFD	Na H antiporter
EI420_01480	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EI420_01495	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EI420_01500	ENOG4108Z1B	Cyclase dehydrase
EI420_01505	ENOG4105VDB	UPF0125 protein
EI420_01510	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EI420_01515	ENOG41090R7	Ferric uptake
EI420_01520	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EI420_01525	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EI420_01530	ENOG4105CFG	Acts as a chaperone (By similarity)
EI420_01535	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI420_01545	ENOG4105E0A	ABC, transporter
EI420_01550	ENOG4105EHG	Permease protein
EI420_01565	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EI420_01570	ENOG4107QUY	Guanine deaminase
EI420_01575	ENOG4105C7W	Xanthine dehydrogenase
EI420_01585	ENOG4105C7N	Xanthine uracil vitamin C permease
EI420_01600	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EI420_01605	ENOG4105HBR	Rna-binding protein
EI420_01610	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EI420_01615	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EI420_01620	ENOG4105EEI	dihydropteroate synthase
EI420_01625	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EI420_01630	ENOG4105CP7	Triose-phosphate isomerase
EI420_01635	ENOG4107EJC	Preprotein translocase subunit SecG
EI420_01650	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EI420_01655	ENOG4105CHV	Transcription elongation factor NusA
EI420_01660	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EI420_01665	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EI420_01670	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EI420_01675	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EI420_01680	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EI420_01685	ENOG4107RTG	Major Facilitator superfamily
EI420_01690	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_01695	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
EI420_01700	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EI420_01705	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EI420_01710	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI420_01715	ENOG4105DJ0	Poly(A) Polymerase
EI420_01720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_01730	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EI420_01735	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI420_01740	ENOG4105CHM	Aminotransferase
EI420_01745	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EI420_01765	ENOG4108VIA	integral membrane protein
EI420_01770	ENOG4105II7	pyrroline-5-carboxylate reductase
EI420_01775	ENOG4105DFA	alanine racemase domain protein
EI420_01785	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EI420_01790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EI420_01825	ENOG4105D1Q	UPF0246 protein
EI420_01830	ENOG4105CPC	Aldo Keto reductase
EI420_01845	ENOG4108URH	decarboxylase
EI420_01875	ENOG4105C87	Aminotransferase class I and II
EI420_01880	ENOG4107QR8	Thioredoxin
EI420_01885	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_01890	ENOG4108IGT	Dipeptidase
EI420_01905	ENOG4105DF6	Fe-S oxidoreductase
EI420_01910	ENOG4105C10	Electron transfer flavoprotein
EI420_01925	ENOG4105C94	Transporter
EI420_01930	ENOG4105E2A	Dehydrogenase
EI420_01940	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EI420_01955	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
EI420_01960	ENOG4108VHT	MarR family transcriptional regulator
EI420_01965	ENOG4108UAU	isochorismatase
EI420_01970	ENOG4105RE0	Asp Glu hydantoin racemase
EI420_01985	ENOG4108XHQ	(2Fe-2S)-binding domain protein
EI420_01990	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
EI420_02000	ENOG4105CK7	Sodium proline symporter
EI420_02010	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_02020	ENOG4105F38	ABC transporter, permease
EI420_02025	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
EI420_02035	ENOG4105DVW	rieske (2Fe-2S)
EI420_02040	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EI420_02045	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EI420_02060	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EI420_02075	ENOG4105EJQ	L-serine dehydratase
EI420_02090	ENOG410811B	TRANSCRIPTIONal
EI420_02100	ENOG4105IKQ	hydratase
EI420_02105	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
EI420_02125	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
EI420_02135	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
EI420_02145	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_02160	ENOG4108YXU	transcriptional regulator AsnC family
EI420_02175	ENOG4105C8J	)-transporter
EI420_02185	ENOG4105CHR	reductase
EI420_02195	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EI420_02200	ENOG4107QMS	site-determining protein
EI420_02205	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EI420_02210	ENOG4105CJB	Exodeoxyribonuclease I
EI420_02215	ENOG4107QXK	peptidase
EI420_02235	ENOG4108JU6	CBS domain protein
EI420_02240	ENOG4106KVJ	cytochrome C assembly protein
EI420_02245	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI420_02250	ENOG4105K5M	30s ribosomal protein S16
EI420_02255	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EI420_02260	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EI420_02265	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EI420_02270	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI420_02275	ENOG4105T95	Thiol disulfide interChange protein
EI420_02280	ENOG4105D6E	homoserine dehydrogenase
EI420_02285	ENOG4105D98	threonine synthase
EI420_02290	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EI420_02310	ENOG4105C59	p-type ATPase
EI420_02330	ENOG4105CRK	lysyL-tRNA synthetase
EI420_02335	ENOG4106032	Glutathionylspermidine synthase
EI420_02360	ENOG4108P9J	Phage shock protein A
EI420_02375	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EI420_02380	ENOG4105M85	Bola protein
EI420_02395	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
EI420_02400	ENOG4106H78	methyltransferase
EI420_02405	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EI420_02410	ENOG4105CAK	Cell division ATP-binding protein ftsE
EI420_02415	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
EI420_02420	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI420_02425	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EI420_02430	ENOG4105CAS	nag kinase
EI420_02445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EI420_02450	ENOG4105W5Q	DNA repair protein (RadC
EI420_02455	ENOG4105KDC	50s ribosomal protein l28
EI420_02460	ENOG4105W0E	50S ribosomal protein L33
EI420_02465	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EI420_02470	ENOG4105DR4	Methyltransferase
EI420_02480	ENOG4105DCF	alanine dehydrogenase
EI420_02490	ENOG4105VEQ	Cold shock protein
EI420_02500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EI420_02505	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
EI420_02515	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
EI420_02520	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
EI420_02525	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EI420_02530	ENOG4105CE9	30S ribosomal protein S2
EI420_02535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EI420_02540	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EI420_02545	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EI420_02550	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EI420_02555	ENOG4105KNE	Phosphatidate cytidylyltransferase
EI420_02560	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EI420_02565	ENOG4105DZP	Membrane-associated zinc metalloprotease
EI420_02580	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI420_02585	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EI420_02590	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI420_02595	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI420_02600	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EI420_02605	ENOG4105C0B	DNA polymerase III (alpha subunit)
EI420_02610	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EI420_02615	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EI420_02620	ENOG4105C9X	ppx gppa phosphatase
EI420_02625	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EI420_02630	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EI420_02635	ENOG4107QK7	reductase
EI420_02640	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EI420_02695	ENOG4108VGW	abc transporter atp-binding protein
EI420_02700	ENOG4105CXZ	ABC transporter, permease
EI420_02705	ENOG4105VNH	ABC transporter solute-binding protein
EI420_02730	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EI420_02745	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EI420_02750	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EI420_02755	ENOG4108M8S	permease YjgP YjgQ family protein
EI420_02760	ENOG4108K5H	permease YjgP YjgQ family protein
EI420_02775	ENOG4108UQY	Iron-storage protein
EI420_02780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EI420_02795	ENOG4105C3U	ABC transporter
EI420_02805	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EI420_02810	ENOG4105DR9	pseudouridine synthase
EI420_02815	ENOG4105CUZ	uba thif-type nad fad binding protein
EI420_02835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EI420_02850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EI420_02860	ENOG4105CPD	ethanolamine ammonia-lyase
EI420_02870	ENOG4105CUB	amino acid
EI420_02880	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EI420_02890	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EI420_02895	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EI420_02900	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
EI420_02905	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EI420_02910	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EI420_02915	ENOG4106IUH	DTW domain containing protein
EI420_02930	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EI420_02935	ENOG4105C1A	potassium transporter peripheral membrane
EI420_02940	ENOG4105WKW	Pfam:DUF1458
EI420_02945	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EI420_02950	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EI420_02955	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EI420_02965	ENOG4105C79	DNA protecting protein DprA
EI420_02970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EI420_02975	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EI420_02980	ENOG4105E2X	shikimate dehydrogenase
EI420_03000	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EI420_03005	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EI420_03010	ENOG4105N21	Membrane
EI420_03015	ENOG4105CUT	histidyl-tRNA synthetase
EI420_03020	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EI420_03035	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EI420_03040	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EI420_03050	ENOG4105C3J	Cysteine desulfurase
EI420_03055	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EI420_03060	ENOG4105D7W	serine acetyltransferase
EI420_03070	ENOG4105ECY	inositol monophosphatase
EI420_03085	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EI420_03090	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EI420_03095	ENOG4105VIE	preprotein translocase, subunit YajC
EI420_03100	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EI420_03105	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EI420_03115	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI420_03160	ENOG4105MEH	
EI420_03180	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI420_03190	ENOG4105SB3	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EI420_03205	ENOG4105CY0	Metallo-Beta-Lactamase
EI420_03220	ENOG4105M4H	endoribonuclease L-psp
EI420_03225	ENOG4105CIF	Ornithine Cyclodeaminase
EI420_03250	ENOG4105DGU	Histone deacetylase
EI420_03255	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EI420_03260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EI420_03270	ENOG4108JQ6	ABC transporter
EI420_03275	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EI420_03285	ENOG4105DEF	Extracellular solute-binding protein, family 5
EI420_03340	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
EI420_03345	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EI420_03350	ENOG4105DWV	Homoserine O-trans-acetylase
EI420_03355	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EI420_03360	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EI420_03365	ENOG4105CNG	UPF0061 protein
EI420_03370	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EI420_03390	ENOG4105BZU	Histidine kinase
EI420_03395	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EI420_03400	ENOG4105C1G	acyl-Coa dehydrogenase
EI420_03405	ENOG4108PVQ	transcriptional regulator
EI420_03425	ENOG4108JQC	penicillin-binding protein 1A
EI420_03450	ENOG4105E4G	Type IV pilus
EI420_03455	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EI420_03460	ENOG4105D49	3-dehydroquinate synthase
EI420_03465	ENOG4105CBC	glutamate synthase
EI420_03470	ENOG4105BZ8	glutamate synthase
EI420_03475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EI420_03480	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EI420_03485	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EI420_03490	ENOG4108Z4U	Ferredoxin
EI420_03495	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EI420_03500	ENOG4107TH8	cina domain protein
EI420_03505	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EI420_03515	ENOG4108MKI	Glycosyl transferase, family 2
EI420_03525	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
EI420_03540	ENOG4105Y3E	Modulates RecA activity (By similarity)
EI420_03545	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EI420_03550	ENOG4105CFH	Aspartokinase
EI420_03555	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EI420_03575	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EI420_03585	ENOG4107QSA	Oxaloacetate decarboxylase
EI420_03590	ENOG4105D9Q	decarboxylase (Beta subunit)
EI420_03595	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EI420_03605	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EI420_03610	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EI420_03615	ENOG41060IM	Heme exporter protein
EI420_03625	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EI420_03630	ENOG4105DA4	cytochrome c-type biogenesis protein
EI420_03635	ENOG4107QX9	Thiol disulfide interChange protein
EI420_03640	ENOG4105KWW	Biogenesis protein
EI420_03650	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EI420_03655	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
EI420_03660	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EI420_03670	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EI420_03675	ENOG4105K9H	YciI-like protein
EI420_03680	ENOG4105DB7	PHP domain protein
EI420_03685	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EI420_03700	ENOG4105EYW	Ion transport protein
EI420_03710	ENOG4107IX6	phosphate transport regulator
EI420_03715	ENOG4105CJ3	phosphate transporter
EI420_03720	ENOG4108EKC	n-acetylglutamate synthase
EI420_03725	ENOG4107R0W	ABC transporter
EI420_03730	ENOG4105E5Q	amino acid AbC transporter
EI420_03735	ENOG4105CDA	abc transporter atp-binding protein
EI420_03750	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EI420_03755	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EI420_03760	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EI420_03785	ENOG4105EXG	Transcriptional regulator
EI420_03790	ENOG4105F27	Major Facilitator
EI420_03795	ENOG4105CKW	Inner membrane protein yedI
EI420_03825	ENOG4105C2C	drug resistance transporter, Bcr CflA
EI420_03830	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EI420_03835	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
EI420_03845	ENOG4105C22	threonyL-tRNA synthetase
EI420_03850	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EI420_03880	ENOG4108Z6Z	Transcriptional regulator
EI420_03890	ENOG4105DJ2	Major Facilitator Superfamily
EI420_03900	ENOG4105Y49	secretion protein, HlyD family
EI420_03910	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
EI420_03920	ENOG4108SF5	RNA Polymerase
EI420_03925	ENOG4108S3W	Anti-feci sigma factor, fecr
EI420_03930	ENOG4105E0K	tonB-dependent siderophore receptor
EI420_03940	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
EI420_03945	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EI420_03950	ENOG4105BZU	Histidine kinase
EI420_03955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI420_03980	ENOG4105HEI	LysR family (Transcriptional regulator
EI420_03985	ENOG4105CHJ	isochorismatase hydrolase
EI420_03995	ENOG4105EUB	pirin domain protein
EI420_04000	ENOG4105EUB	pirin domain protein
EI420_04010	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EI420_04035	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_04045	ENOG4105DHI	Methyltransferase
EI420_04050	ENOG4105VEQ	Cold shock protein
EI420_04055	ENOG4107Y2X	deaminase
EI420_04065	ENOG4105CHB	tonB-dependent Receptor
EI420_04070	ENOG4105DZG	Dehydrogenase
EI420_04075	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EI420_04080	ENOG4105K6T	rare lipoprotein A
EI420_04115	ENOG4105BZU	Histidine kinase
EI420_04120	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EI420_04145	ENOG4105FAV	ABC, transporter
EI420_04150	ENOG4105FDK	ABC transporter
EI420_04160	ENOG4105E0A	ABC, transporter
EI420_04165	ENOG4105NRA	50s ribosomal protein l31 type b
EI420_04170	ENOG4105YK5	50S ribosomal protein L36
EI420_04175	ENOG4105ECY	inositol monophosphatase
EI420_04185	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
EI420_04195	ENOG4105IBP	Cyclic peptide transporter
EI420_04210	ENOG4107EPK	O-methyltransferase, family 2
EI420_04230	ENOG4105E0K	tonB-dependent siderophore receptor
EI420_04240	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
EI420_04245	ENOG4105C5W	Aldolase
EI420_04250	ENOG4108HK0	-acetyltransferase
EI420_04265	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EI420_04295	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EI420_04310	ENOG4107QZF	nitrite reductase NADPH large subunit
EI420_04315	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EI420_04325	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EI420_04345	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EI420_04365	ENOG4105FGV	Chromate
EI420_04370	ENOG4105CAH	Chromate
EI420_04375	ENOG4108WYP	Transcriptional regulator
EI420_04390	ENOG4105DEN	Luciferase family
EI420_04395	ENOG4105EMU	Dehydrogenase
EI420_04425	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
EI420_04430	ENOG4105DR5	peptidase
EI420_04435	ENOG4105C5Q	Transcriptional regulator
EI420_04440	ENOG4105CHF	Glutathione S-transferase
EI420_04460	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
EI420_04465	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EI420_04470	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EI420_04475	ENOG4108Z86	Glutamine amidotransferase
EI420_04485	ENOG4105D8X	mechanosensitive ion channel
EI420_04495	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EI420_04515	ENOG4105EE0	oxidoreductase
EI420_04520	ENOG4107T3P	ABC, transporter
EI420_04525	ENOG41060NJ	transcriptional regulator
EI420_04535	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EI420_04540	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
EI420_04545	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
EI420_04550	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EI420_04555	ENOG4105D9N	nucleoside
EI420_04560	ENOG4108NFH	Sugar hydrolase
EI420_04565	ENOG4107FB0	transcriptional regulator DeoR family
EI420_04570	ENOG4105E2S	oxidase) subunit II
EI420_04575	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EI420_04580	ENOG4105CCU	oxidase (Subunit III)
EI420_04585	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
EI420_04590	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EI420_04595	ENOG4108MAJ	Membrane
EI420_04610	ENOG4105CH5	extracellular solute-binding protein, family 7
EI420_04620	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_04625	ENOG4105Y49	secretion protein, HlyD family
EI420_04635	ENOG4107QPK	)-transporter
EI420_04650	ENOG4105ETU	transcriptional activator (TenA
EI420_04675	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
EI420_04690	ENOG410645S	MarR family Transcriptional regulator
EI420_04710	ENOG4105HP8	regulator of competence-specific genes
EI420_04715	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EI420_04730	ENOG4105C57	major facilitator superfamily
EI420_04735	ENOG41082YX	Transcriptional regulator, arsr family
EI420_04750	ENOG4105C2C	drug resistance transporter, Bcr CflA
EI420_04760	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
EI420_04770	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EI420_04780	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EI420_04795	ENOG4107T8Q	Glycosyl transferase (Group 1
EI420_04805	ENOG4107QJN	gtp cyclohydrolase ii
EI420_04820	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
EI420_04825	ENOG4105DJ9	glucan biosynthesis protein
EI420_04850	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
EI420_04860	ENOG4105CMI	transporter
EI420_04865	ENOG4105CJ1	ABC, transporter
EI420_04870	ENOG4105D0S	secretion protein (HlyD
EI420_04885	ENOG4105CSU	acyl-Coa dehydrogenase
EI420_04895	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_04900	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI420_04905	ENOG4105E39	Enoyl-CoA hydratase
EI420_04915	ENOG4108RXX	maleylacetoacetate isomerase
EI420_04920	ENOG4108VWS	Yaeq family
EI420_04945	ENOG4105CYM	Glutathione S-transferase
EI420_04955	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EI420_04960	ENOG4105K56	Transcriptional regulator
EI420_04965	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EI420_04975	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_04980	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EI420_04985	ENOG4105DIQ	Transcriptional regulator
EI420_05000	ENOG4108Z9K	Osmotically inducible protein
EI420_05005	ENOG4108PXI	ErfK YbiS YcfS YnhG
EI420_05010	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EI420_05035	ENOG4105EGD	dinuclear metal center protein, YbgI family
EI420_05050	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
EI420_05060	ENOG4108IJ9	(ABC) transporter
EI420_05065	ENOG4107YBY	Hydrolase
EI420_05070	ENOG4105CHR	reductase
EI420_05075	ENOG4107Z1W	Fructose transport system kinase
EI420_05080	ENOG4105DEI	Mannitol dehydrogenase
EI420_05085	ENOG4105CMG	Carbohydrate kinase
EI420_05090	ENOG4105FGM	Fructosamine kinase
EI420_05095	ENOG4105DFG	type I secretion outer membrane protein
EI420_05100	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EI420_05130	ENOG4105DHQ	Histidine kinase
EI420_05135	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI420_05140	ENOG41080IJ	Diacylglycerol kinase
EI420_05150	ENOG4105DIJ	Phosphoethanolamine transferase
EI420_05160	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EI420_05195	ENOG4105VZ1	Replication Protein
EI420_05265	ENOG4106V8H	Nucleoid-associated protein
EI420_05390	ENOG4105KUS	lysozyme
EI420_05430	ENOG4105ED4	portal protein
EI420_05460	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EI420_05475	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EI420_05480	ENOG4105BZN	citrate synthase
EI420_05485	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
EI420_05490	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
EI420_05495	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EI420_05500	ENOG4105E33	succinate dehydrogenase
EI420_05505	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EI420_05510	ENOG4105C7S	Dehydrogenase
EI420_05515	ENOG4107QN2	dihydrolipoyl dehydrogenase
EI420_05525	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EI420_05535	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EI420_05540	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
EI420_05545	ENOG4105FDP	GntR family transcriptional regulator
EI420_05550	ENOG4105CE4	GlcNAc 6-P deacetylase
EI420_05555	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EI420_05560	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EI420_05565	ENOG4105CI1	PTS System
EI420_05580	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
EI420_05585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EI420_05590	ENOG4105E0F	Histidine kinase
EI420_05600	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
EI420_05605	ENOG4105DRS	transport system, permease
EI420_05610	ENOG4108IJ9	(ABC) transporter
EI420_05615	ENOG4105C94	Transporter
EI420_05620	ENOG4105CBG	Sulfatase
EI420_05625	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_05635	ENOG4105CM6	amino acid regulated cytosolic protein
EI420_05645	ENOG4105DSB	aldose 1-epimerase
EI420_05660	ENOG4107TT5	NLP P60 protein
EI420_05665	ENOG41080V3	Major Facilitator superfamily
EI420_05675	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EI420_05690	ENOG4105DEF	Extracellular solute-binding protein, family 5
EI420_05695	ENOG4105MRR	Transcriptional regulator (By similarity)
EI420_05700	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EI420_05710	ENOG4108XTF	Outer Membrane Lipoprotein
EI420_05715	ENOG4107RET	Isocitrate lyase
EI420_05725	ENOG4105EZE	Cupin 4 family protein
EI420_05730	ENOG4107QTF	adenylosuccinate lyase
EI420_05735	ENOG41075W9	High frequency lysogenization protein HflD homolog
EI420_05740	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EI420_05750	ENOG4108R99	pseudouridine synthase
EI420_05755	ENOG4105E9K	Isocitrate dehydrogenase
EI420_05760	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EI420_05765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EI420_05770	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EI420_05775	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EI420_05780	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EI420_05785	ENOG4105CNU	cell division protein FtsK
EI420_05785	ENOG4105CNU	cell division protein FtsK
EI420_05790	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EI420_05795	ENOG4105D1H	recombination factor protein RarA
EI420_05805	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EI420_05810	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
EI420_05815	ENOG4105C7I	Dehydrogenase
EI420_05820	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EI420_05825	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
EI420_05830	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EI420_05845	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
EI420_05850	ENOG4105D0M	Protease HtpX homolog
EI420_05855	ENOG4105CHM	Aminotransferase
EI420_05860	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EI420_05865	ENOG4105E0X	reductase
EI420_05900	ENOG4105DA5	(ABC) transporter
EI420_05905	ENOG4105E3A	(ABC) transporter
EI420_05910	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EI420_05915	ENOG41069NU	Nitroreductase
EI420_05950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EI420_05955	ENOG4105FB2	class II Aldolase
EI420_05960	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EI420_05975	ENOG4105C8J	)-transporter
EI420_05985	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EI420_06000	ENOG4108DG9	Smr protein MutS2
EI420_06005	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EI420_06010	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EI420_06025	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
EI420_06040	ENOG4107V40	secretion protein, HlyD family
EI420_06050	ENOG4105CI2	imidazolone-5-propionate hydrolase
EI420_06060	ENOG4108JU5	Magnesium and cobalt efflux protein
EI420_06065	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EI420_06070	ENOG4105C9A	Phoh family
EI420_06075	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EI420_06095	ENOG4105DFP	Integrase
EI420_06150	ENOG41082YX	Transcriptional regulator, arsr family
EI420_06155	ENOG4105CBN	LysR family transcriptional regulator
EI420_06160	ENOG4105CHR	reductase
EI420_06180	ENOG4105CN1	protease
EI420_06185	ENOG4105DFM	M18 family aminopeptidase
EI420_06195	ENOG4105C3G	gtp-binding protein
EI420_06200	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EI420_06205	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EI420_06210	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EI420_06220	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EI420_06225	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
EI420_06230	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
EI420_06235	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EI420_06240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EI420_06245	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EI420_06250	ENOG4105EW9	transcriptional regulator AsnC family
EI420_06255	ENOG4105D06	uba thif-type nad fad binding protein
EI420_06260	ENOG4108JU3	Alkyl hydroperoxide reductase
EI420_06265	ENOG4105D3R	alkyl hydroperoxide reductase
EI420_06275	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_06280	ENOG4105F38	ABC transporter, permease
EI420_06285	ENOG4105D38	putrescine abc transporter
EI420_06300	ENOG4105BZS	acriflavin resistance protein
EI420_06325	ENOG4105NE1	Conserved Protein
EI420_06330	ENOG4105HDD	phospholipase
EI420_06335	ENOG4105EGS	Mechanosensitive ion channel
EI420_06340	ENOG4105DX0	Hemolysin A
EI420_06360	ENOG4106MWK	domain protein
EI420_06365	ENOG4105FQ6	thiopurine methyltransferase
EI420_06385	ENOG4108IJ6	ABC transporter
EI420_06390	ENOG4105ECW	sulfate abc transporter
EI420_06395	ENOG4108I5D	sulfate abc transporter
EI420_06400	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
EI420_06405	ENOG4105DJV	ribulose-phosphate 3-epimerase
EI420_06410	ENOG4105CEP	NADH dehydrogenase
EI420_06415	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EI420_06420	ENOG4105DSE	periplasmic solute binding protein
EI420_06425	ENOG4105DDQ	anthranilate synthase
EI420_06430	ENOG4107QYG	anthranilate phosphoribosyltransferase
EI420_06435	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EI420_06455	ENOG41084HI	prevent-host-death family
EI420_06470	ENOG4105M6W	Crispr-associated protein, Csy3 family
EI420_06490	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EI420_06500	ENOG4105DSF	transport protein
EI420_06505	ENOG4105K63	Thioredoxin
EI420_06510	ENOG4107R11	Transcriptional regulator
EI420_06515	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EI420_06520	ENOG4105CRQ	synthase (Component I)
EI420_06525	ENOG4105DRR	Transcriptional regulator, GntR family
EI420_06530	ENOG4105CR4	methylisocitrate lyase
EI420_06535	ENOG4105BZN	citrate synthase
EI420_06540	ENOG4108I0Z	Aconitate hydratase
EI420_06545	ENOG4105C7F	AcnD-accessory protein PrpF
EI420_06550	ENOG4105KQC	Competence protein
EI420_06555	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EI420_06560	ENOG4105CFV	Tetratricopeptide repeat protein
EI420_06570	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EI420_06575	ENOG4105Y75	tpr repeat protein
EI420_06585	ENOG4108IYU	L-aspartate oxidase
EI420_06610	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EI420_06615	ENOG4105WH1	Two component transcriptional regulator luxr family
EI420_06625	ENOG4105DBV	ornithine carbamoyltransferase
EI420_06630	ENOG4105M2J	Glutaredoxin
EI420_06635	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EI420_06640	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EI420_06645	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EI420_06655	ENOG4105VNG	YcgL domain-containing protein
EI420_06665	ENOG4108ZZ3	UPF0260 protein
EI420_06680	ENOG4105E7A	Glutamine amidotransferase
EI420_06685	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_06690	ENOG4105CQ7	ATP-dependent helicase
EI420_06700	ENOG410903C	(LipO)protein
EI420_06715	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EI420_06720	ENOG4105C2C	drug resistance transporter, Bcr CflA
EI420_06735	ENOG4105C8U	phosphate abc transporter
EI420_06745	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EI420_06750	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EI420_06765	ENOG4105K89	arsenate reductase
EI420_06770	ENOG4105D6J	arsenicaL-resistance protein
EI420_06775	ENOG4105CAU	Arsenical resistance protein, ArsH
EI420_06785	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_06790	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_06795	ENOG4108RZE	Tetr family transcriptional regulator
EI420_06810	ENOG4105CSU	acyl-Coa dehydrogenase
EI420_06830	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
EI420_06855	ENOG4107QI1	Mate efflux family protein
EI420_06860	ENOG4108BPE	-transporting atpase
EI420_06870	ENOG4105F8V	Hydrolase, tatD family
EI420_06880	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_06885	ENOG4105C1G	acyl-Coa dehydrogenase
EI420_06890	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_06895	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_06905	ENOG4105C5H	ABC transporter
EI420_06910	ENOG41081QV	Universal stress protein
EI420_06935	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_06955	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EI420_06970	ENOG4105C3K	feS assembly ATPase SufC
EI420_06980	ENOG4105C9B	Cysteine desulfurase
EI420_07000	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI420_07015	ENOG4105WP7	tRNA pseudouridine synthase C
EI420_07020	ENOG4105EIF	outer membrane protein W
EI420_07025	ENOG4105CK7	Sodium proline symporter
EI420_07030	ENOG4105C26	Dehydrogenase
EI420_07055	ENOG4105EMK	carboxylate amino acid amine transporter
EI420_07105	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EI420_07115	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_07125	ENOG4105VT2	5-hydroxyisourate hydrolase
EI420_07135	ENOG4108FUF	Transcriptional regulator, IclR family
EI420_07140	ENOG41060W2	glyoxylate carboligase
EI420_07145	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
EI420_07150	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EI420_07165	ENOG4107QSN	dihydrolipoamide acetyltransferase
EI420_07170	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EI420_07175	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
EI420_07205	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
EI420_07220	ENOG4107QP8	phosphohexose isomerase
EI420_07225	ENOG4105DM4	PTS System
EI420_07230	ENOG4105DE4	1-phosphofructokinase
EI420_07235	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EI420_07240	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
EI420_07245	ENOG4108Z5K	methylglyoxal synthase
EI420_07250	ENOG4105CA9	Pyruvate kinase
EI420_07255	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EI420_07265	ENOG4108IJ9	(ABC) transporter
EI420_07270	ENOG4105CG3	alpha amylase, catalytic region
EI420_07285	ENOG4107T3P	ABC, transporter
EI420_07295	ENOG41061ZR	Transcriptional regulator
EI420_07300	ENOG4105CG3	alpha amylase, catalytic region
EI420_07315	ENOG4105K6V	RNA polymerase
EI420_07325	ENOG4105C1A	potassium transporter peripheral membrane
EI420_07335	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EI420_07340	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EI420_07345	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
EI420_07355	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
EI420_07360	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EI420_07365	ENOG4105EG2	ABC transporter, permease
EI420_07370	ENOG4105D56	permease protein
EI420_07375	ENOG4107FKK	extracellular solute-binding protein family 1
EI420_07380	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EI420_07385	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
EI420_07390	ENOG4108UHU	Aldolase
EI420_07405	ENOG4105D7K	pfkb domain protein
EI420_07415	ENOG4105CHC	glucokinase (EC 2.7.1.2)
EI420_07420	ENOG4105C01	Dihydroxy-acid dehydratase
EI420_07425	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
EI420_07435	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
EI420_07440	ENOG4107QZB	decarboxylase
EI420_07445	ENOG4108YZT	Adenosylcobinamide kinase
EI420_07450	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
EI420_07455	ENOG4105CVJ	phosphoglycerate mutase
EI420_07465	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EI420_07470	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
EI420_07475	ENOG4105EHG	Permease protein
EI420_07480	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EI420_07485	ENOG410631K	Membrane
EI420_07495	ENOG4105E0A	ABC, transporter
EI420_07500	ENOG4105EHG	Permease protein
EI420_07515	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
EI420_07520	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EI420_07525	ENOG4107QRP	cobalamin biosynthesis protein CobW
EI420_07530	ENOG4105CTK	cobaltochelatase, cobn subunit
EI420_07555	ENOG4105QUC	reductase
EI420_07570	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
EI420_07580	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
EI420_07585	ENOG4107YB6	acetyltransferase, (GNAT) family
EI420_07600	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EI420_07605	ENOG4105C1J	atp-dependent rna helicase
EI420_07615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EI420_07645	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EI420_07665	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
EI420_07675	ENOG4108Z4X	TRANSCRIPTIONal
EI420_07685	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EI420_07715	ENOG4105NAE	bifunctional deaminase-reductase domain protein
EI420_07740	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_07755	ENOG4105US7	Histidine kinase
EI420_07765	ENOG4105Y49	secretion protein, HlyD family
EI420_07780	ENOG410645S	MarR family Transcriptional regulator
EI420_07800	ENOG41073TP	transcriptional regulator
EI420_07825	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
EI420_07830	ENOG4108NIW	Leucine export protein LeuE
EI420_07835	ENOG4108YXU	transcriptional regulator AsnC family
EI420_07845	ENOG4108TM9	integral membrane protein
EI420_07855	ENOG4108VP3	Lysine exporter protein (LysE YggA)
EI420_07860	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EI420_07865	ENOG4105CSV	Glutaminase
EI420_07870	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EI420_07895	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EI420_07900	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EI420_07930	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
EI420_07935	ENOG4107YNJ	LysR family Transcriptional regulator
EI420_07940	ENOG4108JQ7	(ABC) transporter
EI420_07945	ENOG4105C3U	ABC transporter
EI420_07950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EI420_07955	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EI420_07970	ENOG4105DFU	Cell wall formation (By similarity)
EI420_07975	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EI420_07980	ENOG410829K	Lysine exporter protein (Lyse ygga)
EI420_07985	ENOG4108KF1	Membrane
EI420_08000	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EI420_08005	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EI420_08015	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EI420_08020	ENOG4105CJN	penicillin-binding protein
EI420_08025	ENOG4105CNI	cell division protein FtsW
EI420_08030	ENOG4105CVE	Lytic murein transglycosylase
EI420_08040	ENOG4105DZ1	carboxypeptidase
EI420_08045	ENOG41084BA	UPF0250 protein
EI420_08050	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EI420_08055	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EI420_08060	ENOG4105DUM	transcriptional regulator, lysR family
EI420_08070	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EI420_08090	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EI420_08095	ENOG4108JA2	transcriptioN-repair coupling factor
EI420_08105	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI420_08110	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI420_08115	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI420_08120	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI420_08125	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EI420_08130	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
EI420_08140	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
EI420_08165	ENOG4105C8T	Leucyl-tRNA synthetase
EI420_08200	ENOG41082W1	Cupin 2, conserved barrel domain protein
EI420_08205	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EI420_08210	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EI420_08275	ENOG4107UIE	peptidase
EI420_08280	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
EI420_08285	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
EI420_08290	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
EI420_08295	ENOG4108S3N	antar domain-containing protein
EI420_08300	ENOG4105IW1	AmiS UreI transporter
EI420_08315	ENOG4105CC0	LysR family Transcriptional regulator
EI420_08340	ENOG4107NQ8	LysR family Transcriptional regulator
EI420_08345	ENOG4105KNA	-acetyltransferase
EI420_08355	ENOG4108MP6	LysR family Transcriptional regulator
EI420_08360	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EI420_08365	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EI420_08370	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EI420_08375	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EI420_08390	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EI420_08395	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EI420_08400	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EI420_08405	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EI420_08410	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EI420_08425	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EI420_08430	ENOG4105C28	cystathionine
EI420_08435	ENOG4105DS1	cytochrome b561
EI420_08440	ENOG4108YYC	ycei family
EI420_08455	ENOG4105CGF	Aromatic amino acid aminotransferase
EI420_08460	ENOG41090A4	Pterin carbinolamine dehydratase
EI420_08465	ENOG4105BZU	Histidine kinase
EI420_08470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EI420_08485	ENOG4105DHP	deoxycytidine triphosphate deaminase
EI420_08490	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EI420_08495	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EI420_08500	ENOG4105C02	permease
EI420_08505	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
EI420_08520	ENOG4105C9Q	fumarate hydratase class II
EI420_08545	ENOG4105D01	(LipO)protein
EI420_08550	ENOG4108UMI	ABC transporter, permease
EI420_08555	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EI420_08560	ENOG4108R6K	riboflavin synthase, subunit alpha
EI420_08565	ENOG4105C7N	Xanthine uracil vitamin C permease
EI420_08570	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EI420_08575	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EI420_08580	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EI420_08585	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EI420_08590	ENOG4105C2W	permease
EI420_08595	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
EI420_08600	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EI420_08605	ENOG4108ZAF	Molybdopterin
EI420_08625	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EI420_08630	ENOG4105U5Y	Transcriptional regulator
EI420_08635	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EI420_08640	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
EI420_08645	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EI420_08650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EI420_08660	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EI420_08665	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EI420_08670	ENOG4107QIJ	Aconitate hydratase 2
EI420_08675	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
EI420_08685	ENOG4105KRS	Proteinase inhibitor
EI420_08695	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EI420_08700	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EI420_08715	ENOG4105HDK	L-asparaginase
EI420_08720	ENOG4105DJ2	Major Facilitator Superfamily
EI420_08730	ENOG4105C1J	atp-dependent rna helicase
EI420_08740	ENOG4105DY2	Paraquat-inducible protein b
EI420_08745	ENOG4105F1S	paraquat-inducible protein a
EI420_08760	ENOG4108JJ9	ABC, transporter
EI420_08765	ENOG4108JJ8	(ABC) transporter
EI420_08770	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EI420_08800	ENOG4107QUY	Guanine deaminase
EI420_08810	ENOG4105C7W	Xanthine dehydrogenase
EI420_08820	ENOG4108R86	Transcriptional regulator
EI420_08825	ENOG4105CQ7	ATP-dependent helicase
EI420_08845	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
EI420_08850	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EI420_08855	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
EI420_08860	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
EI420_08890	ENOG4105CDV	Ompa motb domain protein
EI420_08895	ENOG4105C22	threonyL-tRNA synthetase
EI420_08900	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EI420_08905	ENOG41082NX	50s ribosomal protein l35
EI420_08910	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EI420_08915	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EI420_08920	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EI420_08925	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EI420_08935	ENOG4105QDK	Flavodoxin
EI420_08945	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EI420_08950	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EI420_08955	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EI420_08960	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EI420_08965	ENOG4105K70	DNA-binding protein
EI420_08970	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EI420_08975	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EI420_08980	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EI420_08985	ENOG4105CX6	glutaminyL-tRNA synthetase
EI420_08990	ENOG4105C8N	cysteinyl-tRNA synthetase
EI420_08995	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
EI420_09000	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
EI420_09005	ENOG4108IJ8	ABC transporter
EI420_09010	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
EI420_09015	ENOG4107R0V	Pyruvate dehydrogenase
EI420_09020	ENOG4105CPP	Dehydrogenase, E1 component
EI420_09025	ENOG4107QSN	dihydrolipoamide acetyltransferase
EI420_09055	ENOG4105CHH	sulfate transporter
EI420_09060	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_09065	ENOG4105FR1	rard protein
EI420_09075	ENOG4105I08	Pseudouridine synthase
EI420_09080	ENOG4108JQ5	ABC transporter
EI420_09085	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
EI420_09090	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
EI420_09100	ENOG4105E9H	Lytic Murein transglycosylase
EI420_09105	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EI420_09115	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EI420_09120	ENOG4108JDX	DNA polymerase iii, epsilon subunit
EI420_09125	ENOG4105E09	nadh pyrophosphatase
EI420_09135	ENOG4105ERU	peptidase
EI420_09140	ENOG41080HT	Transcriptional regulator, arsr family
EI420_09145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EI420_09150	ENOG4105EX9	Membrane
EI420_09160	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
EI420_09165	ENOG4107Z6I	Thiamine biosynthesis protein
EI420_09170	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
EI420_09290	ENOG4105BZU	Histidine kinase
EI420_09335	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EI420_09470	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EI420_09505	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EI420_09510	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EI420_09515	ENOG4105DNZ	Alpha Beta Hydrolase
EI420_09520	ENOG4107SET	aldo keto reductase
EI420_09525	ENOG4108MN8	Membrane
EI420_09545	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
EI420_09560	ENOG4105CD5	CoA-binding domain protein
EI420_09565	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EI420_09580	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EI420_09590	ENOG4108DG9	Smr protein MutS2
EI420_09600	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EI420_09605	ENOG4107QI1	Mate efflux family protein
EI420_09610	ENOG4105C3R	Methionine synthase
EI420_09615	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EI420_09620	ENOG4108WUH	Transcriptional regulator, TetR family
EI420_09635	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EI420_09640	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EI420_09645	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EI420_09650	ENOG4105MYN	Zinc uptake regulation protein
EI420_09665	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI420_09670	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
EI420_09675	ENOG4108JPW	Aminotransferase
EI420_09680	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
EI420_09685	ENOG4105DC8	reductase
EI420_09690	ENOG41077A9	carbonic anhydrase
EI420_09700	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EI420_09710	ENOG4105CFU	surface antigen
EI420_09720	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EI420_09725	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EI420_09730	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EI420_09735	ENOG4105UBK	short-chain dehydrogenase reductase
EI420_09745	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EI420_09750	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EI420_09760	ENOG4105M8F	Biopolymer transport protein exbD tolR
EI420_09765	ENOG4105E02	MotA TolQ exbB proton channel
EI420_09770	ENOG4107YD3	Thioesterase
EI420_09775	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EI420_09780	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EI420_09785	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EI420_09790	ENOG4105C9M	aspartyl-trna synthetase
EI420_09800	ENOG4105C5I	Dehydrogenase
EI420_09805	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
EI420_09810	ENOG4107S2Z	UPF0761 membrane protein
EI420_09820	ENOG4107YNJ	LysR family Transcriptional regulator
EI420_09825	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EI420_09835	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
EI420_09840	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EI420_09855	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EI420_09860	ENOG4105EYA	deoxyribonuclease
EI420_09865	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EI420_09885	ENOG4107VFR	oxidoreductase
EI420_09910	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EI420_09915	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EI420_09920	ENOG4105EKE	dihydroorotase
EI420_09930	ENOG4108TQ9	Histidine kinase
EI420_09935	ENOG4108UYB	regulatoR
EI420_09950	ENOG41090BQ	Glutaredoxin
EI420_09965	ENOG4105D6N	CoA-transferase, subunit a
EI420_09970	ENOG4105GZI	Transcriptional regulator
EI420_09980	ENOG41063SB	peptidase
EI420_09985	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EI420_09990	ENOG4105BZG	amino acid carrier protein
EI420_09995	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EI420_10000	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI420_10005	ENOG4108WAV	Transcriptional regulator
EI420_10010	ENOG4105EWT	decarboxylase family
EI420_10060	ENOG4107QHF	type ii secretion system protein e
EI420_10070	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
EI420_10075	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EI420_10080	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EI420_10095	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
EI420_10105	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EI420_10110	ENOG4105CAT	Cytidine monophosphate kinase
EI420_10115	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EI420_10125	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EI420_10130	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI420_10135	ENOG4108TGP	Thioesterase superfamily protein
EI420_10140	ENOG4105DH7	May be involved in recombination (By similarity)
EI420_10155	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EI420_10175	ENOG4105DGN	Electron transport complex
EI420_10180	ENOG4108R3D	Electron transport complex
EI420_10190	ENOG4105D6A	Electron transport complex
EI420_10200	ENOG4105DZB	Electron transport complex
EI420_10205	ENOG4105CSM	endonuclease III
EI420_10215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI420_10220	ENOG4108IRC	dna polymerase iii
EI420_10230	ENOG4105BZU	Histidine kinase
EI420_10245	ENOG4105CDH	Citrulline--aspartate ligase
EI420_10250	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
EI420_10255	ENOG4105CTQ	phosphohexokinase
EI420_10265	ENOG4105F0N	pyrophosphate phospho-hydrolase
EI420_10275	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EI420_10280	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EI420_10285	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EI420_10290	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EI420_10295	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
EI420_10300	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EI420_10305	ENOG4105C26	Dehydrogenase
EI420_10310	ENOG4105EUJ	GTP cyclohydrolase i
EI420_10320	ENOG4105E27	serine threonine protein kinase
EI420_10350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EI420_10560	ENOG4105H40	
EI420_10605	ENOG4105CHR	reductase
EI420_10615	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EI420_10620	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EI420_10630	ENOG4105D3Y	Na H antiporter
EI420_10635	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EI420_10650	ENOG4105CY2	Citrate transporter
EI420_10665	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EI420_10670	ENOG4105KST	dependent repressor
EI420_10700	ENOG4105K64	Glycosyl transferase, family 2
EI420_10705	ENOG4107T8Q	Glycosyl transferase (Group 1
EI420_10720	ENOG4105D3Q	Sugar transferase
EI420_10725	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EI420_10755	ENOG4105BZ1	(ABC) transporter
EI420_10765	ENOG4105DAY	polysaccharide export protein
EI420_10770	ENOG4107ZF2	Phosphatase
EI420_10775	ENOG4105PF3	O-Antigen polymerase
EI420_10795	ENOG4108DEF	Globin
EI420_10810	ENOG4105EXG	Transcriptional regulator
EI420_10815	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EI420_10825	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EI420_10830	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EI420_10835	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EI420_10840	ENOG41076YT	nitrate reductase, gamma subunit
EI420_10845	ENOG4105R3A	Nitrate reductase
EI420_10850	ENOG4108IUE	nitrate reductase beta subunit
EI420_10855	ENOG4105CRU	nitrate reductase, alpha subunit
EI420_10870	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EI420_10890	ENOG4105BZU	Histidine kinase
EI420_10895	ENOG4105WH1	Two component transcriptional regulator luxr family
EI420_10900	ENOG4105DQQ	Major facilitator superfamily MFS_1
EI420_10910	ENOG4107RNU	major facilitator superfamily MFS_1
EI420_11010	ENOG4107QPN	acyl-Coa dehydrogenase
EI420_11015	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_11020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_11030	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EI420_11045	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EI420_11050	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EI420_11055	ENOG4105E98	transcriptional regulator DeoR family
EI420_11065	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
EI420_11070	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EI420_11075	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EI420_11080	ENOG4108JCI	Transcriptional regulator
EI420_11085	ENOG4105DKK	Benzoate
EI420_11095	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EI420_11110	ENOG4105BZU	Histidine kinase
EI420_11120	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EI420_11130	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EI420_11140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EI420_11145	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_11150	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EI420_11165	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EI420_11205	ENOG4105CV8	reductase
EI420_11220	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
EI420_11245	ENOG4105FTV	AraC Family Transcriptional Regulator
EI420_11260	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EI420_11280	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EI420_11300	ENOG410829K	Lysine exporter protein (Lyse ygga)
EI420_11310	ENOG4105D5U	fad dependent oxidoreductase
EI420_11320	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
EI420_11330	ENOG4105HEI	LysR family (Transcriptional regulator
EI420_11335	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_11340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EI420_11350	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
EI420_11425	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EI420_11430	ENOG4108TGY	Glutathione S-transferase
EI420_11435	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EI420_11440	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI420_11445	ENOG4105C1G	acyl-Coa dehydrogenase
EI420_11455	ENOG4105C32	Amino acid ABC transporter (Permease)
EI420_11465	ENOG4108IV0	ABC, transporter
EI420_11470	ENOG4105C0Z	ABC transporter
EI420_11480	ENOG4105C1G	acyl-Coa dehydrogenase
EI420_11485	ENOG4107QX3	carboxylase
EI420_11490	ENOG4105CGU	Enoyl-CoA hydratase
EI420_11500	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EI420_11505	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_11510	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EI420_11525	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
EI420_11540	ENOG4105FE9	pseudouridine synthase
EI420_11550	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EI420_11555	ENOG4105DXN	mazG family
EI420_11560	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EI420_11565	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EI420_11570	ENOG4105C6T	cysteine synthase
EI420_11575	ENOG4105BZU	Histidine kinase
EI420_11580	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EI420_11585	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EI420_11590	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
EI420_11600	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EI420_11605	ENOG4105C3F	Signal peptidase i
EI420_11610	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EI420_11615	ENOG4105C0H	protease
EI420_11630	ENOG41069E1	anti sigma-E protein RseA
EI420_11635	ENOG4105EMN	RNA polymerase sigma factor
EI420_11640	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EI420_11645	ENOG4105DVT	helicase
EI420_11650	ENOG4105C1J	atp-dependent rna helicase
EI420_11660	ENOG4105CGK	Exodeoxyribonuclease III
EI420_11670	ENOG410822N	TonB family
EI420_11675	ENOG4109015	Biopolymer transport protein exbD tolR
EI420_11705	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EI420_11710	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
EI420_11715	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
EI420_11720	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EI420_11725	ENOG4105C10	Electron transfer flavoprotein
EI420_11730	ENOG4105BZJ	Electron transfer flavoprotein
EI420_11735	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EI420_11750	ENOG4105F8V	Hydrolase, tatD family
EI420_11760	ENOG4107QRG	dna polymerase iii
EI420_11765	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EI420_11770	ENOG4105HHA	aminodeoxychorismate lyase
EI420_11775	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
EI420_11780	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EI420_11785	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EI420_11790	ENOG4105CHR	reductase
EI420_11795	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EI420_11800	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EI420_11805	ENOG4105VGS	50s ribosomal protein l32
EI420_11810	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
EI420_11815	ENOG4108UHJ	MAF-like protein
EI420_11825	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
EI420_11830	ENOG4105EI2	Pseudouridine synthase
EI420_11835	ENOG4107QQB	Ribonuclease E
EI420_11840	ENOG4105D4A	Cell wall formation (By similarity)
EI420_11850	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EI420_11855	ENOG4105W49	UPF0434 protein
EI420_11860	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EI420_11865	ENOG4105BZ1	(ABC) transporter
EI420_11880	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EI420_11885	ENOG4105D60	lipoprotein releasing system transmembrane protein
EI420_11890	ENOG4105DWY	Agmatine deiminase
EI420_11900	ENOG4108UB3	Thiamine monophosphate
EI420_11905	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EI420_11910	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EI420_11925	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EI420_11930	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EI420_11935	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EI420_11940	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
EI420_11945	ENOG4105CPF	Cell wall formation (By similarity)
EI420_11950	ENOG4105DFU	Cell wall formation (By similarity)
EI420_11955	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EI420_11960	ENOG4105CNI	cell division protein FtsW
EI420_11965	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EI420_11970	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EI420_11975	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
EI420_11980	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EI420_11985	ENOG4105CJN	penicillin-binding protein
EI420_11990	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EI420_11995	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EI420_12005	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EI420_12010	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
EI420_12015	ENOG41082RQ	UPF0102 protein
EI420_12020	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EI420_12025	ENOG4105W4M	Transport-associated protein
EI420_12030	ENOG4105KB2	stringent starvation protein b
EI420_12035	ENOG4107MKT	Stringent starvation protein a
EI420_12040	ENOG4105EIX	cytochrome c1
EI420_12045	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EI420_12050	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EI420_12055	ENOG4108UJD	30S ribosomal protein S9
EI420_12060	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EI420_12065	ENOG4105D6Z	AFG1 family ATPase
EI420_12075	ENOG4107QNR	UPF0135 protein
EI420_12080	ENOG4105C0H	protease
EI420_12085	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EI420_12090	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EI420_12095	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EI420_12100	ENOG4105VFK	BolA family
EI420_12115	ENOG4107PE3	Mammalian cell entry related domain protein
EI420_12120	ENOG4105CY3	ABC transporter, permease
EI420_12125	ENOG4105DHJ	ABC, transporter
EI420_12130	ENOG4105C2X	Arabinose 5-phosphate isomerase
EI420_12135	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
EI420_12145	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EI420_12150	ENOG4108IUZ	ABC transporter
EI420_12155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI420_12160	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
EI420_12165	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EI420_12170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EI420_12175	ENOG41080Z8	PHOSPHOCARRIER protein
EI420_12180	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EI420_12185	ENOG4105N42	UPF0307 protein
EI420_12190	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EI420_12200	ENOG4105C03	ribonuclease
EI420_12205	ENOG4108Z03	MAF-like protein
EI420_12215	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EI420_12220	ENOG4105DFF	Rod shape-determining protein mreb
EI420_12225	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EI420_12230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EI420_12235	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EI420_12245	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EI420_12250	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EI420_12265	ENOG410829K	Lysine exporter protein (Lyse ygga)
EI420_12270	ENOG4105VEQ	Cold shock protein
EI420_12280	ENOG4107TE5	Lipid kinase
EI420_12285	ENOG4105CD8	aminopeptidase N
EI420_12290	ENOG4108VPT	UPF0234 protein
EI420_12295	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
EI420_12300	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EI420_12305	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
EI420_12310	ENOG4105EPW	hflc protein
EI420_12320	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EI420_12325	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EI420_12330	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EI420_12335	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EI420_12340	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EI420_12345	ENOG4105K8N	protein family UPF0079, ATPase
EI420_12350	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EI420_12355	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EI420_12360	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EI420_12365	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EI420_12370	ENOG4105KHC	sulfurtransferase
EI420_12375	ENOG4105DJ4	phosphatidylserine decarboxylase
EI420_12380	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EI420_12385	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EI420_12390	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EI420_12405	ENOG4105D65	subunit l
EI420_12410	ENOG4108ZE9	Monovalent cation H antiporter subunit C
EI420_12415	ENOG4107R4Z	monovalent cation h antiporter subunit d
EI420_12420	ENOG4105SC1	monovalent cation H antiporter subunit E
EI420_12425	ENOG4105W4C	monovalent cation H antiporter subunit F
EI420_12430	ENOG4105KJM	monovalent cation h antiporter subunit g
EI420_12440	ENOG4105EAC	phosphoserine phosphatase
EI420_12445	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI420_12450	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_12455	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EI420_12460	ENOG4107QP8	phosphohexose isomerase
EI420_12465	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EI420_12470	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
EI420_12475	ENOG4105Y3U	Transglycosylase-associated protein
EI420_12510	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
EI420_12515	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EI420_12520	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
EI420_12525	ENOG4108SX3	cytoplasmic protein
EI420_12530	ENOG41087AY	ADP-Ribose pyrophosphatase
EI420_12540	ENOG4108RRZ	Transcription elongation factor GreB
EI420_12550	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EI420_12555	ENOG4106371	Methyltransferase
EI420_12560	ENOG4108M60	Transcriptional regulator
EI420_12565	ENOG4105D7K	pfkb domain protein
EI420_12570	ENOG4105C5I	Dehydrogenase
EI420_12575	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
EI420_12585	ENOG4106KNT	transcriptional regulator
EI420_12600	ENOG4108IA2	Sodium pantothenate symporter
EI420_12605	ENOG4105CHW	UPF0052 protein
EI420_12645	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
EI420_12675	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_12680	ENOG4105CZE	histidine utilization repressor
EI420_12685	ENOG4105DWD	nucleoside recognition domain protein
EI420_12690	ENOG4105CI2	imidazolone-5-propionate hydrolase
EI420_12695	ENOG41088SP	formiminoglutamate hydrolase
EI420_12705	ENOG4105C84	Histidine ammonia-lyase
EI420_12710	ENOG4105D3Y	Na H antiporter
EI420_12715	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EI420_12730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_12735	ENOG4108PVQ	transcriptional regulator
EI420_12740	ENOG4108JPW	Aminotransferase
EI420_12745	ENOG4105C26	Dehydrogenase
EI420_12755	ENOG4108RH0	Crea protein
EI420_12760	ENOG4105ENA	helicase
EI420_12765	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
EI420_12775	ENOG4105PGM	cation diffusion facilitator family transporter
EI420_12780	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EI420_12785	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EI420_12790	ENOG4108061	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
EI420_12820	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EI420_12825	ENOG4105C5B	carbamate kinase
EI420_12830	ENOG4105DBV	ornithine carbamoyltransferase
EI420_12835	ENOG4105CEU	Arginine dihydrolase
EI420_12840	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
EI420_12865	ENOG4105ECM	Sensor protein basS pmrB
EI420_12900	ENOG4108RMU	ferritin dps family protein
EI420_12920	ENOG4105G3Z	GntR family transcriptional regulator
EI420_12960	ENOG4105D9Q	decarboxylase (Beta subunit)
EI420_12965	ENOG4107QSA	Oxaloacetate decarboxylase
EI420_12975	ENOG4105DSY	exodeoxyribonuclease V, gamma
EI420_12980	ENOG4107QKA	exodeoxyribonuclease V beta
EI420_12985	ENOG4107QYX	exodeoxyribonuclease v alpha
EI420_12995	ENOG4105D7V	transposase
EI420_13005	ENOG4105C0D	helicase
EI420_13065	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EI420_13170	ENOG4105F2I	Transposase
EI420_13275	ENOG4105BZU	Histidine kinase
EI420_13285	ENOG41084CK	capsule polysaccharide
EI420_13295	ENOG4107T7U	Sulfatase
EI420_13330	ENOG4105NXH	GreA GreB family elongation factor
EI420_13335	ENOG4105D82	Glutamate dehydrogenase
EI420_13370	ENOG4108UK5	Transposase
EI420_13375	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EI420_13380	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
EI420_13415	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EI420_13420	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EI420_13430	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EI420_13475	ENOG4106ECQ	phosphomannomutase
EI420_13480	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EI420_13515	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EI420_13535	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EI420_13540	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EI420_13545	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
EI420_13555	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EI420_13560	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EI420_13570	ENOG4105CY0	Metallo-Beta-Lactamase
EI420_13585	ENOG4107V1M	polysaccharide export protein
EI420_13595	ENOG4105QMY	Porin Gram-negative type
EI420_13600	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
EI420_13610	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EI420_13615	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EI420_13620	ENOG4105HF0	Membrane
EI420_13635	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
EI420_13640	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EI420_13650	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EI420_13660	ENOG4105BZS	acriflavin resistance protein
EI420_13665	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
EI420_13670	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EI420_13675	ENOG4105D9M	gamma-glutamylcysteine synthetase
EI420_13680	ENOG4105BZM	domain protein
EI420_13685	ENOG4105E0X	reductase
EI420_13690	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EI420_13695	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EI420_13700	ENOG4105VEJ	Heat shock protein
EI420_13705	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
EI420_13710	ENOG4107RK2	ADP-ribose diphosphatase NudE
EI420_13715	ENOG4105D9R	oxidoreductase
EI420_13720	ENOG4105C01	Dihydroxy-acid dehydratase
EI420_13725	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EI420_13725	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EI420_13730	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EI420_13740	ENOG4108ZAI	phosphatidylglycerophosphatase a
EI420_13745	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EI420_13750	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EI420_13755	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EI420_13760	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EI420_13765	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EI420_13770	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EI420_13775	ENOG4107QW3	Sucrose phosphorylase
EI420_13780	ENOG4107ZT5	Thiol disulfide interchange protein
EI420_13785	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
EI420_13795	ENOG41090Y2	cytochrome C
EI420_13800	ENOG4105DHQ	Histidine kinase
EI420_13805	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI420_13810	ENOG4105KFG	YeeE YedE family protein
EI420_13830	ENOG4105C3Q	Glycosyl transferase, family 2
EI420_13855	ENOG4108ST3	glycosyltransferase
EI420_13860	ENOG4105PF3	O-Antigen polymerase
EI420_13895	ENOG4105EY8	ABC transporter
EI420_13915	ENOG4105JNK	Glycosyl transferase (Group 1
EI420_13925	ENOG4105D3Q	Sugar transferase
EI420_13940	ENOG4108JJ6	Type I secretion system ATPase
EI420_13945	ENOG4105CGH	5'-nucleotidase
EI420_13955	ENOG4106ECQ	phosphomannomutase
EI420_13960	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EI420_13970	ENOG4105CV6	ABC transporter, permease
EI420_13975	ENOG4108I0Y	(ABC) transporter
EI420_13980	ENOG4108UJV	acyl-CoA thioesterase i
EI420_14040	ENOG4105DFG	type I secretion outer membrane protein
EI420_14045	ENOG4107RT3	EamA-like transporter family
EI420_14055	ENOG4105BZU	Histidine kinase
EI420_14065	ENOG4105C5H	ABC transporter
EI420_14070	ENOG4105K59	histidine triad (HIT) protein
EI420_14075	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
EI420_14085	ENOG4105C12	Phosphoribosylglycinamide synthetase
EI420_14090	ENOG4108NVM	synthesis repressor PhaR
EI420_14100	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EI420_14105	ENOG4105CVE	Lytic murein transglycosylase
EI420_14110	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EI420_14120	ENOG4105KJM	monovalent cation h antiporter subunit g
EI420_14125	ENOG41080TA	Multiple resistance and ph regulation protein f
EI420_14130	ENOG4105SC1	monovalent cation H antiporter subunit E
EI420_14135	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EI420_14140	ENOG4105MKQ	Monovalent cation H antiporter subunit C
EI420_14145	ENOG4105GND	monovalent cation H antiporter subunit B
EI420_14150	ENOG4105D65	subunit l
EI420_14155	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EI420_14160	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
EI420_14180	ENOG4105CDU	Replicative dna helicase
EI420_14185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EI420_14195	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EI420_14200	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EI420_14205	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EI420_14210	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EI420_14250	ENOG4105ED1	spovr family
EI420_14255	ENOG4106AKX	UPF0229 protein
EI420_14260	ENOG4105CYN	Serine protein kinase
EI420_14265	ENOG4105C5W	Aldolase
EI420_14270	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EI420_14275	ENOG4108IPJ	Membrane
EI420_14280	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EI420_14290	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EI420_14295	ENOG4105BZG	amino acid carrier protein
EI420_14305	ENOG4107V8I	Glycosyl transferases group 1
EI420_14310	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
EI420_14315	ENOG4105QNF	Outer membrane lipoprotein
EI420_14320	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EI420_14325	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EI420_14335	ENOG4108JEH	abc transporter atp-binding protein
EI420_14340	ENOG4105DSP	amino acid AbC transporter
EI420_14345	ENOG4106YG3	ABC transporter
EI420_14350	ENOG4106PMH	Extracellular solute-binding protein family 3
EI420_14360	ENOG4105ED2	Beta-lactamase
EI420_14380	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EI420_14385	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EI420_14395	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EI420_14400	ENOG4106WHD	Tetrathionate reductase
EI420_14405	ENOG4105DB1	molybdopterin oxidoreductase
EI420_14415	ENOG4105C01	Dihydroxy-acid dehydratase
EI420_14420	ENOG4105DSY	exodeoxyribonuclease V, gamma
EI420_14435	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EI420_14440	ENOG4107QKA	exodeoxyribonuclease V beta
EI420_14445	ENOG4107QYX	exodeoxyribonuclease v alpha
EI420_14480	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_14495	ENOG4108NIW	Leucine export protein LeuE
EI420_14500	ENOG4105BZU	Histidine kinase
EI420_14505	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EI420_14510	ENOG41081XE	plasmid maintenance system antidote protein, xre family
EI420_14520	ENOG4105C5H	ABC transporter
EI420_14530	ENOG4106NZI	LysR family Transcriptional regulator
EI420_14535	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EI420_14585	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EI420_14590	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EI420_14620	ENOG4107RSM	transcriptional regulator
EI420_14625	ENOG4105CH2	amidohydrolase
EI420_14635	ENOG4105E1V	na solute symporter
EI420_14640	ENOG4105W8I	Transcriptional regulator
EI420_14645	ENOG4107SET	aldo keto reductase
EI420_14665	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
EI420_14680	ENOG4105BZU	Histidine kinase
EI420_14700	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
EI420_14710	ENOG4105DND	Transcriptional regulator
EI420_14715	ENOG4105VRT	cytoplasmic protein
EI420_14735	ENOG4107R7Y	intracellular protease Pfpi family
EI420_14740	ENOG4107XC4	flavin reductase domain protein, FMN-binding
EI420_14745	ENOG4108YZN	class I peptide chain release factor
EI420_14755	ENOG4105CTU	Proline racemase
EI420_14770	ENOG4105D7N	magnesium and cobalt transport protein CorA
EI420_14790	ENOG4105C26	Dehydrogenase
EI420_14795	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_14805	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
EI420_14835	ENOG4105BZU	Histidine kinase
EI420_14850	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
EI420_14870	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_14875	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EI420_14890	ENOG4105EJC	lysr family transcriptional regulator
EI420_14895	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EI420_14900	ENOG4105CIS	alcohol dehydrogenase
EI420_14905	ENOG4108ZT1	Transcriptional regulator
EI420_14920	ENOG4105EWC	Purine nucleoside phosphorylase
EI420_14925	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
EI420_14930	ENOG4105C26	Dehydrogenase
EI420_14940	ENOG4105F4X	arginine
EI420_14945	ENOG4105C8Y	Acetylornithine aminotransferase
EI420_14950	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_14960	ENOG4105RKW	reductase (By
EI420_14970	ENOG4108V06	Glutathione peroxidase
EI420_14980	ENOG4105CDY	transcriptional regulatory protein
EI420_15000	ENOG4105CB2	alcohol dehydrogenase
EI420_15005	ENOG4105BZ1	(ABC) transporter
EI420_15010	ENOG4108KK1	membrane protein AbrB duplication
EI420_15020	ENOG4105C1J	atp-dependent rna helicase
EI420_15025	ENOG4108Z66	YbaK ebsC protein
EI420_15045	ENOG4108IAB	Phoh family
EI420_15050	ENOG4107U9T	Pfam:Ribonuclease_BN
EI420_15065	ENOG4105VEQ	Cold shock protein
EI420_15075	ENOG4105C26	Dehydrogenase
EI420_15080	ENOG4105DUM	transcriptional regulator, lysR family
EI420_15090	ENOG4105C26	Dehydrogenase
EI420_15095	ENOG4108ZAI	phosphatidylglycerophosphatase a
EI420_15105	ENOG4105EYH	Exonuclease
EI420_15110	ENOG4107RFY	SbcCD D subunit
EI420_15120	ENOG4105C8P	)-transporter
EI420_15125	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
EI420_15135	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
EI420_15155	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_15180	ENOG4105E1J	oxidoreductase
EI420_15190	ENOG4108XM1	transcriptional regulator AsnC family
EI420_15195	ENOG4108MES	Periplasmic binding protein
EI420_15200	ENOG4105DQ5	transport system permease protein
EI420_15205	ENOG4108IHU	transport system permease protein
EI420_15215	ENOG4105E0A	ABC, transporter
EI420_15240	ENOG4105KPY	Small multidrug resistance protein
EI420_15275	ENOG41090U3	tautomerase
EI420_15280	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
EI420_15305	ENOG4105C26	Dehydrogenase
EI420_15310	ENOG4105EGI	Transcriptional regulator
EI420_15315	ENOG4108WUH	Transcriptional regulator, TetR family
EI420_15320	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
EI420_15350	ENOG4105EHG	Permease protein
EI420_15355	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EI420_15365	ENOG4105D05	Receptor
EI420_15375	ENOG4105BZ1	(ABC) transporter
EI420_15380	ENOG4105E0A	ABC, transporter
EI420_15385	ENOG4108IHU	transport system permease protein
EI420_15390	ENOG4105DQ5	transport system permease protein
EI420_15395	ENOG4108MES	Periplasmic binding protein
EI420_15400	ENOG4105D05	Receptor
EI420_15410	ENOG4105BZS	acriflavin resistance protein
EI420_15415	ENOG4105D05	Receptor
EI420_15420	ENOG4108R4R	Iron-regulated virulence regulatory protein
EI420_15435	ENOG4105BZU	Histidine kinase
EI420_15440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_15450	ENOG4108IJ7	Glycine betaine
EI420_15465	ENOG4105C94	Transporter
EI420_15485	ENOG4108IPJ	Membrane
EI420_15490	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EI420_15495	ENOG4105C4W	S-formylglutathione hydrolase
EI420_15505	ENOG4105CC0	LysR family Transcriptional regulator
EI420_15510	ENOG4105EJQ	L-serine dehydratase
EI420_15520	ENOG4105CFC	Transporter
EI420_15525	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI420_15530	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EI420_15535	ENOG4105VCC	30S ribosomal protein S21
EI420_15540	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EI420_15545	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EI420_15560	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EI420_15565	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EI420_15570	ENOG4105NWN	ApaG protein
EI420_15575	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EI420_15580	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EI420_15585	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EI420_15590	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EI420_15595	ENOG4105EHM	Aminoglycoside phosphotransferase
EI420_15600	ENOG4108S0S	Nucleotidyl transferase
EI420_15605	ENOG4108UKZ	OsmC family
EI420_15610	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
EI420_15615	ENOG4105D1S	lipid A biosynthesis
EI420_15620	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EI420_15625	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EI420_15630	ENOG4108K5P	(LipO)protein
EI420_15640	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EI420_15645	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EI420_15650	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EI420_15655	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EI420_15660	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
EI420_15665	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EI420_15675	ENOG4107RGH	Aldehyde dehydrogenase
EI420_15680	ENOG4106KNT	transcriptional regulator
EI420_15690	ENOG4105EW9	transcriptional regulator AsnC family
EI420_15695	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EI420_15710	ENOG41084A1	Protein CrcB homolog
EI420_15715	ENOG4105WMR	Protein CrcB homolog
EI420_15725	ENOG4105CHH	sulfate transporter
EI420_15730	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EI420_15735	ENOG4108WQI	RNA Polymerase
EI420_15750	ENOG4107SDU	Methyl-accepting chemotaxis
EI420_15755	ENOG4105D3R	alkyl hydroperoxide reductase
EI420_15765	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
EI420_15770	ENOG4105CKI	cobalamin synthesis protein
EI420_15775	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI420_15785	ENOG4105F0N	pyrophosphate phospho-hydrolase
EI420_15790	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
EI420_15805	ENOG4105C8Y	Acetylornithine aminotransferase
EI420_15810	ENOG4105C26	Dehydrogenase
EI420_15830	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
EI420_15835	ENOG4108RYR	transcriptional regulator AsnC family
EI420_15840	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
EI420_15845	ENOG4105ENR	peptidase, M24
EI420_15860	ENOG4105DWU	Membrane
EI420_15875	ENOG4105HDK	L-asparaginase
EI420_15890	ENOG4105JQN	Transcriptional regulator
EI420_15895	ENOG4105DDY	UPF0142 protein ycaO
EI420_15900	ENOG41067SE	Tetr family transcriptional regulator
EI420_15905	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EI420_15915	ENOG4108WUH	Transcriptional regulator, TetR family
EI420_15930	ENOG4105EB3	Histidine kinase
EI420_15935	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EI420_15950	ENOG4105KAF	membrAne
EI420_15960	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI420_15965	ENOG41062D9	Histidine kinase
EI420_15990	ENOG4105C94	Transporter
EI420_15995	ENOG4105CHH	sulfate transporter
EI420_16005	ENOG4105C26	Dehydrogenase
EI420_16015	ENOG4105BZU	Histidine kinase
EI420_16025	ENOG4105BZU	Histidine kinase
EI420_16055	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_16065	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EI420_16070	ENOG4108594	Permease of the drug metabolite transporter
EI420_16080	ENOG4108IJ6	ABC transporter
EI420_16085	ENOG4105E0C	molybdate abc transporter
EI420_16090	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EI420_16095	ENOG4105CA9	Pyruvate kinase
EI420_16105	ENOG4108Z2U	ureidoglycolate hydrolase
EI420_16110	ENOG4105S0E	allantoin catabolism protein
EI420_16120	ENOG410633P	Hydantoin racemase
EI420_16130	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
EI420_16150	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
EI420_16165	ENOG4105DAA	L-lactate
EI420_16175	ENOG4105CQB	FAD linked oxidase domain protein
EI420_16180	ENOG4105EU8	FAD linked oxidase domain protein
EI420_16185	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EI420_16190	ENOG4108ZJF	Glcg protein
EI420_16225	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
EI420_16240	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
EI420_16245	ENOG4105C58	cytochrome c oxidase accessory protein ccog
EI420_16255	ENOG4105C59	p-type ATPase
EI420_16270	ENOG4105D4P	Coproporphyrinogen iii oxidase
EI420_16280	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EI420_16300	ENOG4107QN1	sodium solute
EI420_16310	ENOG4105BZU	Histidine kinase
EI420_16320	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EI420_16340	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
EI420_16345	ENOG41072GX	Peptidase M22 Glycoprotease
EI420_16350	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EI420_16355	ENOG4107QSN	dihydrolipoamide acetyltransferase
EI420_16360	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EI420_16365	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EI420_16370	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EI420_16380	ENOG4108R96	Methyltransferase, YaeB family
EI420_16385	ENOG4105BZU	Histidine kinase
EI420_16455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI420_16460	ENOG4105C8V	SAICAR synthetase
EI420_16470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EI420_16475	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI420_16485	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EI420_16490	ENOG4105ERG	peptidase m48, ste24p
EI420_16495	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EI420_16550	ENOG4105FE9	pseudouridine synthase
EI420_16555	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EI420_16565	ENOG4105CFI	type iii restriction protein res subunit
EI420_16570	ENOG4105E9F	Enoyl-CoA hydratase
EI420_16575	ENOG4108ETH	Formylglycinamide ribotide synthetase
EI420_16580	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EI420_16585	ENOG4108Z6B	deaminase
EI420_16590	ENOG4105C29	acyl-CoA thioesterase
EI420_16595	ENOG4105C6K	Malic enzyme
EI420_16600	ENOG4105VFB	Binds the 23S rRNA (By similarity)
EI420_16605	ENOG4105C25	Primosomal protein n'
EI420_16610	ENOG4105C75	arginyL-tRNA synthetase
EI420_16620	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EI420_16625	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EI420_16645	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EI420_16650	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
EI420_16655	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EI420_16660	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EI420_16670	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
EI420_16675	ENOG4105D52	delta-aminolevulinic acid dehydratase
EI420_16685	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EI420_16690	ENOG4105DZ2	Transcriptional regulator
EI420_16695	ENOG4105JJR	Histidine kinase
EI420_16700	ENOG4107EXC	regulatoR
EI420_16705	ENOG4108WIW	Aspartyl protease
EI420_16730	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EI420_16735	ENOG41080IJ	Diacylglycerol kinase
EI420_16755	ENOG4107RX2	synthase
EI420_16760	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EI420_16765	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
EI420_16770	ENOG4107R73	Mate efflux family protein
EI420_16775	ENOG4105CRW	Short chain fatty acid transporter
EI420_16790	ENOG4107SQD	Transcriptional regulator, GntR family
EI420_16835	ENOG4105BZW	Glycerate kinase
EI420_16840	ENOG4108RMU	ferritin dps family protein
EI420_16845	ENOG4105CIN	aminoacyl-histidine dipeptidase
EI420_16850	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EI420_16855	ENOG4105CH5	extracellular solute-binding protein, family 7
EI420_16865	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_16870	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
EI420_16875	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_16880	ENOG4107QKW	extracellular solute-binding protein family 1
EI420_16885	ENOG4105C2M	dna polymerase I
EI420_16900	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
EI420_16905	ENOG4105EV8	ectoine hydroxylase
EI420_16915	ENOG4105JQN	Transcriptional regulator
EI420_16970	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EI420_16975	ENOG4105CEN	a g-specific adenine glycosylase
EI420_16990	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EI420_16995	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EI420_17000	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EI420_17005	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EI420_17015	ENOG4105R2J	Conserved Protein
EI420_17025	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
EI420_17030	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
EI420_17035	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EI420_17045	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EI420_17065	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EI420_17070	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EI420_17075	ENOG4105EMY	transcriptional regulator
EI420_17080	ENOG4108ZP8	Acetolactate synthase small subunit
EI420_17085	ENOG4105C7K	acetolactate synthase
EI420_17090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EI420_17095	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EI420_17100	ENOG4105C34	Pseudouridine synthase
EI420_17105	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI420_17110	ENOG4105C4K	Nad synthetase
EI420_17120	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EI420_17130	ENOG4105C3M	thioredoxin reductase
EI420_17135	ENOG4107QM5	aconitate hydratase
EI420_17140	ENOG4107R1I	NAD-dependent malic enzyme
EI420_17145	ENOG41066VF	YeeE YedE family protein
EI420_17150	ENOG4105C31	Tryptophanyl-tRNA synthetase
EI420_17175	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EI420_17180	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EI420_17190	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EI420_17195	ENOG4105DTN	riboflavin biosynthesis protein ribF
EI420_17200	ENOG4105CJR	Integral membrane protein (MviN
EI420_17205	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
EI420_17210	ENOG4105CDA	abc transporter atp-binding protein
EI420_17215	ENOG4105E5Q	amino acid AbC transporter
EI420_17220	ENOG4105EAB	amino acid AbC transporter
EI420_17225	ENOG4108UW5	maltose o-acetyltransferase
EI420_17240	ENOG4105DTS	flagellar hook-associated
EI420_17245	ENOG4105DTS	flagellar hook-associated
EI420_17275	ENOG4105E3A	(ABC) transporter
EI420_17280	ENOG4105DA5	(ABC) transporter
EI420_17285	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
EI420_17305	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_17315	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
EI420_17320	ENOG4105EMU	Dehydrogenase
EI420_17330	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EI420_17335	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EI420_17340	ENOG4105C26	Dehydrogenase
EI420_17345	ENOG4105C7K	acetolactate synthase
EI420_17350	ENOG4105DWD	nucleoside recognition domain protein
EI420_17355	ENOG4105CYW	agmatinase
EI420_17360	ENOG4108JUB	Transcriptional regulator
EI420_17380	ENOG4105DRS	transport system, permease
EI420_17385	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
EI420_17390	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
EI420_17395	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
EI420_17400	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
EI420_17410	ENOG4105WDR	
EI420_17415	ENOG4105E98	transcriptional regulator DeoR family
EI420_17425	ENOG4108I5D	sulfate abc transporter
EI420_17435	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EI420_17445	ENOG4105DXI	Major Facilitator superfamily
EI420_17450	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_17460	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_17465	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EI420_17470	ENOG4105BZU	Histidine kinase
EI420_17475	ENOG4105CBS	Chea signal transduction histidine kinase
EI420_17480	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_17485	ENOG4105BZU	Histidine kinase
EI420_17500	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EI420_17505	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EI420_17520	ENOG4105QAX	Iron-sulfur
EI420_17525	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EI420_17555	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EI420_17560	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EI420_17565	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EI420_17570	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EI420_17575	ENOG4105CKI	cobalamin synthesis protein
EI420_17580	ENOG4105BZU	Histidine kinase
EI420_17585	ENOG4105EVZ	LysR family transcriptional regulator
EI420_17590	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
EI420_17600	ENOG4105CD3	dihydroorotase
EI420_17605	ENOG4105BZ8	glutamate synthase
EI420_17610	ENOG4107SJI	Dehydrogenase
EI420_17635	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
EI420_17640	ENOG4105DZC	cytosine deaminase
EI420_17655	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EI420_17660	ENOG4105VE1	Phosphatidylcholine synthase
EI420_17665	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EI420_17680	ENOG4105HKU	nucleoside recognition domain-containing protein
EI420_17690	ENOG4108R86	Transcriptional regulator
EI420_17695	ENOG4105C26	Dehydrogenase
EI420_17700	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EI420_17715	ENOG4105DRR	Transcriptional regulator, GntR family
EI420_17720	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EI420_17725	ENOG4105DV0	amidase (EC 3.5.1.4
EI420_17730	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
EI420_17735	ENOG4108JPW	Aminotransferase
EI420_17740	ENOG4105C26	Dehydrogenase
EI420_17745	ENOG4105CUB	amino acid
EI420_17770	ENOG4105DFD	Na H antiporter
EI420_17775	ENOG4105C26	Dehydrogenase
EI420_17780	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EI420_17785	ENOG4108Z86	Glutamine amidotransferase
EI420_17790	ENOG4105CFQ	glutamine synthetase
EI420_17795	ENOG4105CJP	fad dependent oxidoreductase
EI420_17800	ENOG4105ENR	peptidase, M24
EI420_17810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EI420_17820	ENOG4105C5H	ABC transporter
EI420_17850	ENOG4107R11	Transcriptional regulator
EI420_17855	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
EI420_17865	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_17875	ENOG4105BZS	acriflavin resistance protein
EI420_17890	ENOG4105CC0	LysR family Transcriptional regulator
EI420_17920	ENOG4107ENK	receptor
EI420_17930	ENOG4107R4I	Periplasmic binding protein
EI420_17935	ENOG4105EHG	Permease protein
EI420_17940	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EI420_17945	ENOG4105WD1	Membrane
EI420_17950	ENOG4105CJW	magnesium transporter
EI420_17955	ENOG4105C26	Dehydrogenase
EI420_17965	ENOG4105C26	Dehydrogenase
EI420_17975	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
EI420_17980	ENOG4105D7K	pfkb domain protein
EI420_17990	ENOG4105C2J	ABC transporter
EI420_17995	ENOG4107RNG	ABC transporter
EI420_18005	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
EI420_18015	ENOG4105DH8	myo-inositol catabolism
EI420_18030	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
EI420_18035	ENOG4107STF	Involved in phosphonate degradation (By similarity)
EI420_18045	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EI420_18050	ENOG4105C4Y	ABC transporter
EI420_18065	ENOG4105BZU	Histidine kinase
EI420_18075	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_18090	ENOG4105C5Q	Transcriptional regulator
EI420_18100	ENOG4105E7W	lamb ycsf family protein
EI420_18105	ENOG4105P4J	Allophanate hydrolase, subunit 1
EI420_18115	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EI420_18120	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EI420_18125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EI420_18140	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
EI420_18145	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
EI420_18170	ENOG4105DZG	Dehydrogenase
EI420_18215	ENOG4105CYW	agmatinase
EI420_18230	ENOG4108K0D	peptidase, M48
EI420_18235	ENOG4107HP6	Transcriptional regulator
EI420_18255	ENOG4105ES4	Nitrilase
EI420_18260	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_18280	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_18285	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI420_18290	ENOG4105CD5	CoA-binding domain protein
EI420_18295	ENOG4105CGU	Enoyl-CoA hydratase
EI420_18310	ENOG4108PGP	mmge prpd family protein
EI420_18315	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EI420_18325	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EI420_18330	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EI420_18335	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EI420_18355	ENOG4105D6U	Sodium Glutamate Symporter
EI420_18365	ENOG4105CH2	amidohydrolase
EI420_18370	ENOG4105CFC	Transporter
EI420_18375	ENOG4105F04	LysR family Transcriptional regulator
EI420_18385	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_18390	ENOG4105C26	Dehydrogenase
EI420_18395	ENOG4105DFD	Na H antiporter
EI420_18400	ENOG4105CJP	fad dependent oxidoreductase
EI420_18405	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_18420	ENOG4105CEY	Amp-dependent synthetase and ligase
EI420_18425	ENOG4105E39	Enoyl-CoA hydratase
EI420_18430	ENOG4107HP6	Transcriptional regulator
EI420_18450	ENOG4105E32	cytoplasmic protein
EI420_18455	ENOG4105CQB	FAD linked oxidase domain protein
EI420_18460	ENOG4108JPW	Aminotransferase
EI420_18475	ENOG4105ETT	transcriptional Regulator, LysR family
EI420_18480	ENOG4105DTQ	mandelate racemase muconate lactonizing
EI420_18485	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
EI420_18490	ENOG4105CH2	amidohydrolase
EI420_18495	ENOG4108KB2	LysR family Transcriptional regulator
EI420_18520	ENOG4105IW1	AmiS UreI transporter
EI420_18535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_18540	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
EI420_18545	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EI420_18575	ENOG4105I7I	quinohemoprotein amine dehydrogenase gamma subunit
EI420_18600	ENOG4105E39	Enoyl-CoA hydratase
EI420_18605	ENOG4108UKI	Enoyl-CoA hydratase
EI420_18610	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI420_18615	ENOG4108ZJI	phenylacetic acid degradation protein
EI420_18620	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_18625	ENOG4105DZS	Phenylacetate-CoA ligase
EI420_18630	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
EI420_18635	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
EI420_18640	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
EI420_18645	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
EI420_18650	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EI420_18655	ENOG4105DXM	phenylacetic acid degradation protein
EI420_18660	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_18695	ENOG4105F1J	Homogentisate 1,2-dioxygenase
EI420_18705	ENOG4108RXX	maleylacetoacetate isomerase
EI420_18710	ENOG4105C2C	drug resistance transporter, Bcr CflA
EI420_18735	ENOG4105C8J	)-transporter
EI420_18745	ENOG4108JU8	Transcriptional regulator
EI420_18750	ENOG4105F7P	transcriptional regulator AsnC family
EI420_18755	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
EI420_18765	ENOG4107S6Z	Na H antiporter
EI420_18795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EI420_18815	ENOG4105CRW	Short chain fatty acid transporter
EI420_18830	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
EI420_18835	ENOG4105CHU	acetyl-coa acetyltransferase
EI420_18865	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EI420_18870	ENOG4105E39	Enoyl-CoA hydratase
EI420_18880	ENOG4105C1G	acyl-Coa dehydrogenase
EI420_18885	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EI420_18910	ENOG4105K8K	Cupin 2, conserved barrel
EI420_18935	ENOG4105DUM	transcriptional regulator, lysR family
EI420_18940	ENOG4105HMI	Membrane
EI420_18955	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
EI420_18960	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
EI420_18975	ENOG4108WAV	Transcriptional regulator
EI420_18980	ENOG41079YP	Citrate utilization protein b
EI420_18985	ENOG4107EFR	Flavocytochrome c
EI420_19015	ENOG4105CHR	reductase
EI420_19020	ENOG4105C7K	acetolactate synthase
EI420_19030	ENOG4105KHC	sulfurtransferase
EI420_19035	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_19045	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EI420_19055	ENOG4105CQB	FAD linked oxidase domain protein
EI420_19060	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EI420_19065	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
EI420_19070	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_19075	ENOG4105ECQ	AraC Family Transcriptional Regulator
EI420_19085	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_19100	ENOG4107QIZ	NADH dehydrogenase
EI420_19105	ENOG4108JB9	formate dehydrogenase
EI420_19110	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EI420_19120	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EI420_19125	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EI420_19130	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
EI420_19135	ENOG4105CQM	Urea amidohydrolase subunit alpha
EI420_19140	ENOG4105KI2	Urea amidohydrolase subunit beta
EI420_19145	ENOG4108YZ9	Urea amidohydrolase subunit gamma
EI420_19155	ENOG4105CNM	Receptor
EI420_19165	ENOG4105DQ5	transport system permease protein
EI420_19170	ENOG4108U1V	ABC transporter, permease
EI420_19190	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EI420_19195	ENOG4105F4R	Transcriptional regulator mode
EI420_19200	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EI420_19205	ENOG4105E0C	molybdate abc transporter
EI420_19210	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EI420_19230	ENOG4105DSE	periplasmic solute binding protein
EI420_19235	ENOG4105DIK	(ABC) transporter
EI420_19240	ENOG4105CC5	ABC transporter
EI420_19245	ENOG4107RBD	ABC, transporter
EI420_19250	ENOG4108IV0	ABC, transporter
EI420_19255	ENOG4105C0Z	ABC transporter
EI420_19265	ENOG4105C32	Amino acid ABC transporter (Permease)
EI420_19290	ENOG4108V9W	transcriptional regulatory protein
EI420_19295	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
EI420_19310	ENOG4105I03	Flagellin
EI420_19315	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI420_19320	ENOG410642E	Short chain dehydrogenase
EI420_19325	ENOG4105C94	Transporter
EI420_19330	ENOG4105D8X	mechanosensitive ion channel
EI420_19335	ENOG4105W39	Membrane
EI420_19340	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
EI420_19350	ENOG4105C72	UPF0176 protein
EI420_19360	ENOG4108JQ1	Dehydrogenase
EI420_19370	ENOG4105CTB	Polyprenyl synthetase
EI420_19375	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EI420_19380	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EI420_19385	ENOG4108RXX	maleylacetoacetate isomerase
EI420_19400	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
EI420_19405	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EI420_19410	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EI420_19420	ENOG4107QXX	ABC transporter
EI420_19425	ENOG4105EZ7	amino acid ABC transporter
EI420_19430	ENOG4105DRP	amino acid AbC transporter
EI420_19435	ENOG4105CDA	abc transporter atp-binding protein
EI420_19455	ENOG4105S7S	phosphonate abc transporter
EI420_19470	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_19475	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_19480	ENOG4105C8Q	Methyl-accepting chemotaxis
EI420_19490	ENOG4105DP0	ferredoxin-NADP reductase
EI420_19495	ENOG4108YZA	Nitrogen regulatory protein pii
EI420_19505	ENOG4108YZA	Nitrogen regulatory protein pii
EI420_19510	ENOG4105W0Z	cytoplasmic protein
EI420_19530	ENOG4105J76	Periplasmic binding protein
EI420_19535	ENOG4105C0P	Mg chelatase subunit ChlI
EI420_19540	ENOG4108YYH	Nadph-dependent fmn reductase
EI420_19555	ENOG4107QP3	malate synthase g
EI420_19565	ENOG4105M08	Membrane
EI420_19570	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EI420_19580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EI420_19610	ENOG4105C5I	Dehydrogenase
EI420_19625	ENOG4108ZX6	Electron transport protein SCO1 SenC
EI420_19635	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EI420_19640	ENOG41080TK	Universal stress protein
EI420_19645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_19650	ENOG4108K1J	Transporter DctQ
EI420_19655	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
EI420_19665	ENOG4105C5H	ABC transporter
EI420_19670	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EI420_19680	ENOG4105DWF	phosphomethylpyrimidine kinase
EI420_19685	ENOG4105CH5	extracellular solute-binding protein, family 7
EI420_19690	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_19705	ENOG4108Z33	Thiol disulfide Interchange Protein
EI420_19710	ENOG4106RE7	Cytochrome
EI420_19715	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EI420_19720	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
EI420_19725	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EI420_19735	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EI420_19740	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EI420_19750	ENOG4105CH7	arginosuccinase
EI420_19755	ENOG4105BZU	Histidine kinase
EI420_19760	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EI420_19765	ENOG41076E6	Uroporphyrinogen-III Synthase
EI420_19775	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
EI420_19800	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EI420_19810	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
EI420_19820	ENOG4105NN7	muconolactone delta-isomerase
EI420_19825	ENOG4105DTQ	mandelate racemase muconate lactonizing
EI420_19830	ENOG4105F57	Anthranilate dioxygenase reductase
EI420_19835	ENOG4108YS2	small subunit
EI420_19840	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
EI420_19845	ENOG41081XQ	Conserved Protein
EI420_19850	ENOG4105C8J	)-transporter
EI420_19860	ENOG4106KNT	transcriptional regulator
EI420_19865	ENOG4105C4R	Atp-dependent dna helicase
EI420_19870	ENOG4105CH5	extracellular solute-binding protein, family 7
EI420_19875	ENOG4105NAU	thioesterase Superfamily protein
EI420_19885	ENOG4105C8U	phosphate abc transporter
EI420_19890	ENOG4105E2Z	phosphate ABC transporter (Permease
EI420_19895	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EI420_19900	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EI420_19905	ENOG4105EXN	Sulfate transport protein CysZ
EI420_19925	ENOG4105BZU	Histidine kinase
EI420_19930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EI420_19935	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EI420_19940	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
EI420_19945	ENOG4107QZF	nitrite reductase NADPH large subunit
EI420_19950	ENOG4105NYX	DNA-binding protein
EI420_19960	ENOG41090KR	LysR family transcriptional Regulator
EI420_19965	ENOG4105C26	Dehydrogenase
EI420_19975	ENOG4105CH2	amidohydrolase
EI420_19990	ENOG4105EM2	membrane
EI420_20015	ENOG4105CB5	ATP-dependent DNA helicase recG
EI420_20020	ENOG4105C5Q	Transcriptional regulator
EI420_20030	ENOG4105KME	endoribonuclease L-psp
EI420_20035	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EI420_20040	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EI420_20045	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EI420_20055	ENOG4105F27	Major Facilitator
EI420_20065	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EI420_20075	ENOG4105J0Q	Transcriptional regulator
EI420_20080	ENOG4105DSJ	YicC domain protein
EI420_20095	ENOG4105C2J	ABC transporter
EI420_20100	ENOG4105CNN	ABC, transporter
EI420_20105	ENOG4105F5R	ABC transporter
EI420_20110	ENOG4105CMG	Carbohydrate kinase
EI420_20115	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EI420_20125	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EI420_20130	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EI420_20135	ENOG4105C4R	Atp-dependent dna helicase
EI420_20145	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
EI420_20150	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EI420_20155	ENOG4105DHQ	Histidine kinase
EI420_20165	ENOG4105DN9	Na H antiporter
EI420_20170	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EI420_20175	ENOG4105CJ2	(LipO)protein
EI420_20180	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EI420_20190	ENOG4105CJW	magnesium transporter
EI420_20195	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EI420_20200	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EI420_20205	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EI420_20210	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EI420_20215	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EI420_20220	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EI420_20225	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EI420_20230	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EI420_20240	ENOG4105FA0	parb-like partition protein
EI420_20245	ENOG4107QJE	Chromosome Partitioning Protein
EI420_20250	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EI420_20255	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EI420_20260	ENOG4105CDA	abc transporter atp-binding protein
EI420_20265	ENOG4105E5Q	amino acid AbC transporter
EI420_20270	ENOG4107R0W	ABC transporter
EI420_20275	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EI420_20280	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EI420_20290	ENOG4108YXA	Membrane
EI420_20295	ENOG4105DWF	phosphomethylpyrimidine kinase
EI420_20300	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EI420_20320	ENOG4105P8Q	Curli production assembly transport component CsgG
EI420_20335	ENOG41086KC	Transcriptional regulator
EI420_20340	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EI420_20345	ENOG4105CSA	Coproporphyrinogen iii oxidase
EI420_20350	ENOG4108ZG0	Ompa motb domain protein
EI420_20355	ENOG4105D6S	protein involved in catabolism of external DNA
EI420_20360	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EI420_20365	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EI420_20370	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EI420_20375	ENOG4105VG0	50S ribosomal protein l34