locus-tag	class	description
HCD_00005	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HCD_00010	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HCD_00015	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HCD_00020	ENOG4107B2H	carbonic anhydrase
HCD_00060	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HCD_00105	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HCD_00120	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HCD_00130	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HCD_00135	ENOG4105RX8	Protein of unknown function (DUF1523)
HCD_00140	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HCD_00145	ENOG4105BZN	citrate synthase
HCD_00155	ENOG4105DIJ	Phosphoethanolamine transferase
HCD_00170	ENOG4108WZ2	response regulator
HCD_00200	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HCD_00205	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HCD_00225	ENOG4105D5G	Transposase
HCD_00255	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HCD_00290	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HCD_00295	ENOG4105CP7	Triose-phosphate isomerase
HCD_00300	ENOG4108S24	Fumarate reduCtase
HCD_00305	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HCD_00310	ENOG4105E33	succinate dehydrogenase
HCD_00315	ENOG4107RZC	phospholipase d
HCD_00335	ENOG4108UUM	single-stranded DNA-binding protein
HCD_00340	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HCD_00345	ENOG4108VMB	DNA polymerase III subunit delta'
HCD_00350	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HCD_00355	ENOG4105E2X	shikimate dehydrogenase
HCD_00365	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HCD_00370	ENOG4105E43	Extracellular solute-binding protein, family 5
HCD_00375	ENOG4105C31	Tryptophanyl-tRNA synthetase
HCD_00385	ENOG4105NU9	Preprotein translocase subunit SecG
HCD_00390	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HCD_00405	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HCD_00410	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HCD_00415	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HCD_00460	ENOG4105D65	subunit l
HCD_00465	ENOG4105C8S	subunit m
HCD_00470	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HCD_00480	ENOG4107QKV	phosphomannomutase
HCD_00505	ENOG4105ETU	transcriptional activator (TenA
HCD_00540	ENOG4105CRQ	synthase (Component I)
HCD_00545	ENOG4105DDQ	anthranilate synthase
HCD_00550	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HCD_00555	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HCD_00560	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HCD_00645	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HCD_00650	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HCD_00655	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HCD_00685	ENOG4105D4A	Cell wall formation (By similarity)
HCD_00695	ENOG4108JIR	Flagellum-specific ATP synthase
HCD_00705	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HCD_00710	ENOG410854I	s4 domain protein
HCD_00740	ENOG4105C2X	Arabinose 5-phosphate isomerase
HCD_00770	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HCD_00775	ENOG41085EF	Carbon storage regulator
HCD_00785	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HCD_00790	ENOG4105M8K	biopolymer transport protein
HCD_00805	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HCD_00815	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCD_00825	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HCD_00860	ENOG4105CIY	formyltetrahydrofolate deformylase
HCD_00885	ENOG4105K63	Thioredoxin
HCD_01015	ENOG4105D7V	transposase
HCD_01020	ENOG4108RS6	transposase
HCD_01035	ENOG4107SDU	Methyl-accepting chemotaxis
HCD_01045	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HCD_01055	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_01085	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HCD_01090	ENOG4108IUZ	ABC transporter
HCD_01100	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HCD_01105	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HCD_01110	ENOG4105HDK	L-asparaginase
HCD_01125	ENOG4105HMI	Membrane
HCD_01130	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HCD_01140	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HCD_01145	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCD_01170	ENOG4108P97	
HCD_01175	ENOG4108USZ	hydrogenase
HCD_01180	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
HCD_01185	ENOG4105DPX	Hydrogenase, large subunit
HCD_01190	ENOG4108RS6	transposase
HCD_01195	ENOG4105D7V	transposase
HCD_01200	ENOG4105DPX	Hydrogenase, large subunit
HCD_01205	ENOG4105E3S	small subunit
HCD_01235	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HCD_01255	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_01260	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HCD_01265	ENOG4108JQC	penicillin-binding protein 1A
HCD_01300	ENOG4105DQU	oxidoreductase, subunit beta
HCD_01305	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HCD_01325	ENOG4107C5Z	FeoA domain
HCD_01330	ENOG4105CSM	endonuclease III
HCD_01335	ENOG4105DD5	Flagellar motor switch protein
HCD_01350	ENOG4105EKE	dihydroorotase
HCD_01370	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HCD_01375	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HCD_01380	ENOG4105C3F	Signal peptidase i
HCD_01385	ENOG4108Z4T	Peptidase M50
HCD_01390	ENOG4108YZG	isomerase
HCD_01400	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HCD_01405	ENOG4108VD1	dedA family
HCD_01415	ENOG4105C3G	gtp-binding protein
HCD_01425	ENOG4105F4G	Membrane
HCD_01435	ENOG4108KBJ	Inner membrane protein YkgB
HCD_01455	ENOG4105CHR	reductase
HCD_01460	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HCD_01465	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HCD_01490	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HCD_01495	ENOG4105X6C	Flagellar basal body-associated protein FliL
HCD_01525	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HCD_01530	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HCD_01540	ENOG4105C8J	)-transporter
HCD_01545	ENOG4105C8J	)-transporter
HCD_01550	ENOG4105C8J	)-transporter
HCD_01555	ENOG4107YD3	Thioesterase
HCD_01560	ENOG41068HQ	Protein of unknown function (DUF493)
HCD_01590	ENOG4105VFU	Rna-binding protein
HCD_01600	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HCD_01610	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HCD_01625	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HCD_01630	ENOG4105K70	DNA-binding protein
HCD_01650	ENOG4105C5E	polysaccharide biosynthesis protein
HCD_01655	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HCD_01680	ENOG4105I85	Bifunctional alpha-2,3 -2,8-sialyltransferase
HCD_01685	ENOG4105F0R	Cytidylyltransferase
HCD_01690	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HCD_01695	ENOG4105D2T	synthase
HCD_01700	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HCD_01705	ENOG4105DWF	phosphomethylpyrimidine kinase
HCD_01720	ENOG4105C5H	ABC transporter
HCD_01725	ENOG4108RS6	transposase
HCD_01735	ENOG4105D7V	transposase
HCD_01760	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HCD_01765	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HCD_01770	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HCD_01775	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HCD_01790	ENOG4108TX7	
HCD_01800	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HCD_01825	ENOG4105BZE	flagellar hook protein, FlgE
HCD_01830	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HCD_01845	ENOG4105CH6	catalase
HCD_01890	ENOG4105CJR	Integral membrane protein (MviN
HCD_01925	ENOG4107U4J	modification
HCD_01950	ENOG4105DVF	Cytosine-specific methyltransferase
HCD_01955	ENOG4105D7V	transposase
HCD_01960	ENOG4108RS6	transposase
HCD_01965	ENOG4105DVF	Cytosine-specific methyltransferase
HCD_01970	ENOG4107S6Z	Na H antiporter
HCD_01975	ENOG4105KME	endoribonuclease L-psp
HCD_01980	ENOG4107QMZ	Dehydrogenase
HCD_01985	ENOG4105BZG	amino acid carrier protein
HCD_01990	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HCD_01995	ENOG4105EAB	amino acid AbC transporter
HCD_02000	ENOG4105E5Q	amino acid AbC transporter
HCD_02030	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HCD_02040	ENOG4105CEV	competence damage-inducible protein
HCD_02045	ENOG4105C19	ABC transporter
HCD_02075	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HCD_02080	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HCD_02085	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HCD_02090	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HCD_02095	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HCD_02100	ENOG4105EI2	Pseudouridine synthase
HCD_02125	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HCD_02130	ENOG4107QMS	site-determining protein
HCD_02140	ENOG4105C4K	Nad synthetase
HCD_02145	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HCD_02150	ENOG4105VDT	-acetyltransferase
HCD_02155	ENOG4105F0R	Cytidylyltransferase
HCD_02160	ENOG4105F0R	Cytidylyltransferase
HCD_02165	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HCD_02200	ENOG4108WHG	pyridoxamine 5'-phosphate
HCD_02215	ENOG4105D7V	transposase
HCD_02220	ENOG4108RS6	transposase
HCD_02225	ENOG4107QJE	Chromosome Partitioning Protein
HCD_02285	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HCD_02290	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HCD_02300	ENOG4105D49	3-dehydroquinate synthase
HCD_02310	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HCD_02320	ENOG4105DKP	glycosyl transferase, family 9
HCD_02325	ENOG4107R33	ppx gppa phosphatase
HCD_02330	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HCD_02335	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HCD_02345	ENOG4105QTX	Pfam:UPF0153
HCD_02380	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HCD_02385	ENOG4105CD3	dihydroorotase
HCD_02390	ENOG4107QIV	Cytochrome c biogenesis protein
HCD_02395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HCD_02405	ENOG4105UHH	
HCD_02410	ENOG4105D7V	transposase
HCD_02415	ENOG4108RS6	transposase
HCD_02430	ENOG4108KQY	
HCD_02435	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HCD_02470	ENOG4105D1F	ATP-binding protein
HCD_02475	ENOG4108RS6	transposase
HCD_02485	ENOG4105D7V	transposase
HCD_02505	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HCD_02510	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HCD_02515	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HCD_02525	ENOG4105CMR	udp-glucose 4-epimerase
HCD_02540	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HCD_02545	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HCD_02555	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HCD_02560	ENOG4105DZP	Membrane-associated zinc metalloprotease
HCD_02590	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HCD_02595	ENOG4108JQ5	ABC transporter
HCD_02620	ENOG4108J2R	molybdopterin oxidoreductase
HCD_02645	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HCD_02650	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HCD_02660	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HCD_02670	ENOG4108JQ1	Dehydrogenase
HCD_02675	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HCD_02680	ENOG4105DFA	alanine racemase domain protein
HCD_02690	ENOG4107R88	Chemotaxis protein (CheV)
HCD_02695	ENOG4105CBS	Chea signal transduction histidine kinase
HCD_02705	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HCD_02730	ENOG4105EMU	Dehydrogenase
HCD_02750	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HCD_02760	ENOG4105D9N	nucleoside
HCD_02765	ENOG4107RDB	Major Facilitator
HCD_02770	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HCD_02790	ENOG4107RM6	sulfurtransferase
HCD_02795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HCD_02805	ENOG4105DKP	glycosyl transferase, family 9
HCD_02810	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HCD_02820	ENOG4105D7V	transposase
HCD_02825	ENOG4108RS6	transposase
HCD_02830	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HCD_02855	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HCD_02860	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HCD_02870	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HCD_02875	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HCD_02885	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HCD_02890	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HCD_02895	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HCD_02910	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HCD_02915	ENOG4105BZ1	(ABC) transporter
HCD_02940	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HCD_02955	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HCD_02965	ENOG4105C12	Phosphoribosylglycinamide synthetase
HCD_02975	ENOG4105D7V	transposase
HCD_02980	ENOG4108RS6	transposase
HCD_03020	ENOG4105CRK	lysyL-tRNA synthetase
HCD_03030	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HCD_03035	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HCD_03040	ENOG4105D2T	synthase
HCD_03050	ENOG4105D2N	Aldolase
HCD_03055	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HCD_03070	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HCD_03085	ENOG4105CFP	Peptidase U32
HCD_03105	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HCD_03110	ENOG4105D52	delta-aminolevulinic acid dehydratase
HCD_03115	ENOG4105CDY	transcriptional regulatory protein
HCD_03120	ENOG4105EUU	Sel1 domain protein repeat-containing protein
HCD_03160	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HCD_03165	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HCD_03215	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HCD_03220	ENOG4107QPK	)-transporter
HCD_03225	ENOG4105CEN	a g-specific adenine glycosylase
HCD_03235	ENOG4105DAA	L-lactate
HCD_03240	ENOG4105DAA	L-lactate
HCD_03245	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HCD_03250	ENOG4107QR9	Iron-sulfur cluster binding protein
HCD_03260	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HCD_03295	ENOG4107YJQ	MAF-like protein
HCD_03300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HCD_03330	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HCD_03345	ENOG4105DJP	Membrane
HCD_03380	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HCD_03385	ENOG4105C22	threonyL-tRNA synthetase
HCD_03390	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HCD_03415	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_03430	ENOG4108122	heat-inducible transcription repressor
HCD_03450	ENOG4105I03	Flagellin
HCD_03455	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HCD_03460	ENOG41082XB	radical SAM domain protein
HCD_03475	ENOG4105WPN	DNA integration recombination invertion protein
HCD_03480	ENOG4107SDU	Methyl-accepting chemotaxis
HCD_03485	ENOG4107QID	Threonine synthase
HCD_03495	ENOG4105C5I	Dehydrogenase
HCD_03505	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HCD_03510	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HCD_03515	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HCD_03525	ENOG4107RSR	Malate quinone oxidoreductase
HCD_03545	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_03565	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
HCD_03575	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HCD_03580	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HCD_03590	ENOG4105IW1	AmiS UreI transporter
HCD_03600	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HCD_03605	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HCD_03610	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HCD_03630	ENOG4105C26	Dehydrogenase
HCD_03635	ENOG4105CK7	Sodium proline symporter
HCD_03665	ENOG4105ESV	Glycosyl transferase, family 4
HCD_03670	ENOG4105P1V	phosphoesterase PA-phosphatase related protein
HCD_03690	ENOG4108UMI	ABC transporter, permease
HCD_03695	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HCD_03705	ENOG4108R6K	riboflavin synthase, subunit alpha
HCD_03710	ENOG4105F8V	Hydrolase, tatD family
HCD_03720	ENOG4105K6T	rare lipoprotein A
HCD_03725	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HCD_03740	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HCD_03750	ENOG4105CJN	penicillin-binding protein
HCD_03755	ENOG4105D01	(LipO)protein
HCD_03760	ENOG4105D3R	alkyl hydroperoxide reductase
HCD_03770	ENOG4105CNI	cell division protein FtsW
HCD_03775	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HCD_03780	ENOG4108ZC9	flagellar basal-body rod protein flgc
HCD_03790	ENOG4105CJN	penicillin-binding protein
HCD_03800	ENOG41090JH	(ATPase)-like protein
HCD_03820	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HCD_03825	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HCD_03830	ENOG4108JA2	transcriptioN-repair coupling factor
HCD_03840	ENOG4105DR5	peptidase
HCD_03850	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HCD_03860	ENOG4105C8T	Leucyl-tRNA synthetase
HCD_03870	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HCD_03875	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HCD_03880	ENOG4105VIE	preprotein translocase, subunit YajC
HCD_03890	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HCD_03900	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HCD_03930	ENOG4108WF3	methyltransferase
HCD_03935	ENOG4105DVP	Adenine-specific
HCD_03940	ENOG4108ZT0	50S ribosomal protein l17
HCD_03945	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HCD_03950	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HCD_03955	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HCD_03960	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCD_03975	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HCD_03980	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HCD_03985	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HCD_04020	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HCD_04025	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HCD_04030	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HCD_04050	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HCD_04075	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HCD_04080	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HCD_04095	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HCD_04100	ENOG4105C9Q	fumarate hydratase class II
HCD_04120	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HCD_04125	ENOG4108IJF	Heavy metal efflux pump, CzcA
HCD_04145	ENOG41082EK	Restriction modification system DNA (Specificity
HCD_04150	ENOG4105DZR	Type I site-specific deoxyribonuclease
HCD_04170	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HCD_04180	ENOG4105CDU	Replicative dna helicase
HCD_04220	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HCD_04245	ENOG4105CN1	protease
HCD_04255	ENOG4105E9Q	Acyl-transferase
HCD_04260	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HCD_04265	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HCD_04270	ENOG4105BZA	Phosphoglycerate kinase
HCD_04275	ENOG4105D7N	magnesium and cobalt transport protein CorA
HCD_04280	ENOG4105EE5	Membrane protein terC
HCD_04315	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HCD_04320	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HCD_04330	ENOG4105C4R	Atp-dependent dna helicase
HCD_04340	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HCD_04355	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HCD_04360	ENOG4108YXA	Membrane
HCD_04365	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HCD_04380	ENOG4107V40	secretion protein, HlyD family
HCD_04390	ENOG4105C37	(CBS) domain
HCD_04395	ENOG4105CJ3	phosphate transporter
HCD_04400	ENOG41083MR	nifu domain-containing protein
HCD_04410	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HCD_04415	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HCD_04475	ENOG4105C59	p-type ATPase
HCD_04480	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HCD_04490	ENOG4105D6U	Sodium Glutamate Symporter
HCD_04500	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HCD_04505	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HCD_04535	ENOG4105CHV	Transcription elongation factor NusA
HCD_04575	ENOG4105CB5	ATP-dependent DNA helicase recG
HCD_04590	ENOG4105CGK	Exodeoxyribonuclease III
HCD_04625	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HCD_04640	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HCD_04665	ENOG4105C2M	dna polymerase I
HCD_04675	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HCD_04700	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HCD_04705	ENOG4105DJV	ribulose-phosphate 3-epimerase
HCD_04725	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HCD_04730	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HCD_04745	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_04750	ENOG4105DQ4	alcohol dehydrogenase
HCD_04755	ENOG4105DCF	alanine dehydrogenase
HCD_04760	ENOG4108IQI	permease
HCD_04765	ENOG41088SP	formiminoglutamate hydrolase
HCD_04775	ENOG4105C6K	Malic enzyme
HCD_04795	ENOG4105EVN	Prephenate dehydrogenase
HCD_04800	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HCD_04805	ENOG410901F	(LipO)protein
HCD_04810	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
HCD_04825	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HCD_04830	ENOG4105DFF	Rod shape-determining protein mreb
HCD_04855	ENOG4108UMN	azlc family
HCD_04860	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HCD_04870	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HCD_04890	ENOG4105M8K	biopolymer transport protein
HCD_04895	ENOG4105M15	transport protein ExbD
HCD_04900	ENOG41067XB	TonB family
HCD_04920	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HCD_04925	ENOG4107S2Z	UPF0761 membrane protein
HCD_04940	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HCD_04960	ENOG4108MJ5	VirK protein
HCD_04965	ENOG4105CA0	peroxidase
HCD_04970	ENOG4105C0B	DNA polymerase III (alpha subunit)
HCD_04975	ENOG4105FE9	pseudouridine synthase
HCD_05050	ENOG4105VUH	addiction module killer protein
HCD_05070	ENOG4105D7B	Flagellar biosynthesis protein flha
HCD_05075	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
HCD_05085	ENOG4107RN3	metallophosphoesterase
HCD_05105	ENOG4108RS6	transposase
HCD_05110	ENOG4105D7V	transposase
HCD_05115	ENOG4105MZU	cell filamentation protein
HCD_05125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HCD_05135	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HCD_05140	ENOG41080IJ	Diacylglycerol kinase
HCD_05155	ENOG4105D7V	transposase
HCD_05160	ENOG4108RS6	transposase
HCD_05165	ENOG4105PZN	Type II restriction enzyme NlaIV
HCD_05170	ENOG4107V6I	Cytosine-specific methyltransferase
HCD_05180	ENOG4105CE1	Ferrous iron transport protein b
HCD_05185	ENOG4105D7V	transposase
HCD_05190	ENOG4108RS6	transposase
HCD_05205	ENOG4105CN7	Flagellar biosynthetic protein FliP
HCD_05210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HCD_05215	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HCD_05220	ENOG4107R5Z	Oxidoreductase domain protein
HCD_05225	ENOG4105HF0	Membrane
HCD_05240	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HCD_05260	ENOG4105D4P	Coproporphyrinogen iii oxidase
HCD_05280	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HCD_05295	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HCD_05305	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HCD_05310	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HCD_05315	ENOG4105DVY	radical SAM domain protein
HCD_05330	ENOG4105NZ8	inorganic pyro-phosphatase
HCD_05360	ENOG4105C9M	aspartyl-trna synthetase
HCD_05370	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HCD_05390	ENOG4108J2R	molybdopterin oxidoreductase
HCD_05400	ENOG4105QAX	Iron-sulfur
HCD_05420	ENOG4108RWN	rrna methyltransferase
HCD_05425	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HCD_05430	ENOG41082DI	50s ribosomal protein l31
HCD_05435	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HCD_05455	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HCD_05470	ENOG4105C8Q	Methyl-accepting chemotaxis
HCD_05475	ENOG4105C5F	glutamine synthetase
HCD_05495	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HCD_05515	ENOG4105CQB	FAD linked oxidase domain protein
HCD_05520	ENOG4105MRU	Plasminogen-binding protein
HCD_05525	ENOG4107VIJ	nudix hydrolase
HCD_05530	ENOG4105E4C	Lytic transglycosylase catalytic
HCD_05535	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HCD_05555	ENOG4105ZGC	lipoprotein carrier protein
HCD_05565	ENOG4105D60	lipoprotein releasing system transmembrane protein
HCD_05590	ENOG4105C59	p-type ATPase
HCD_05595	ENOG4105C0P	Mg chelatase subunit ChlI
HCD_05600	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HCD_05610	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HCD_05625	ENOG4108BGM	Quinol dehydrogenase periplasmic component
HCD_05630	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HCD_05645	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HCD_05650	ENOG4108ZEX	molybdopterin converting factor, subunit 2
HCD_05660	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HCD_05675	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HCD_05680	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HCD_05685	ENOG4105E0C	molybdate abc transporter
HCD_05690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HCD_05710	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HCD_05720	ENOG4105CHM	Aminotransferase
HCD_05735	ENOG4105C98	muts2 protein
HCD_05745	ENOG4105C3M	thioredoxin reductase
HCD_05755	ENOG41082UM	UPF0102 protein
HCD_05760	ENOG4105D6E	homoserine dehydrogenase
HCD_05805	ENOG4108SEK	ompa motb domain protein
HCD_05815	ENOG4105D06	uba thif-type nad fad binding protein
HCD_05865	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HCD_05870	ENOG4105HFZ	Membrane
HCD_05875	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HCD_05890	ENOG4105VSH	4-oxalocrotonate tautomerase
HCD_05900	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HCD_05905	ENOG4105D0M	Protease HtpX homolog
HCD_05910	ENOG4105EUJ	GTP cyclohydrolase i
HCD_05915	ENOG4105CTB	Polyprenyl synthetase
HCD_05935	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HCD_05945	ENOG4105CI3	gtp-binding protein typa
HCD_05975	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HCD_06020	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HCD_06025	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HCD_06040	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
HCD_06055	ENOG4108IQI	permease
HCD_06060	ENOG4105C0H	protease
HCD_06070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HCD_06075	ENOG4105C2M	dna polymerase I
HCD_06085	ENOG4105DVC	DnaJ domain protein
HCD_06090	ENOG4105KNI	merR family transcriptional Regulator
HCD_06095	ENOG4105D1H	recombination factor protein RarA
HCD_06100	ENOG41090R7	Ferric uptake
HCD_06115	ENOG4105DD5	Flagellar motor switch protein
HCD_06120	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HCD_06125	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HCD_06135	ENOG4107R21	site-determining protein
HCD_06140	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HCD_06145	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCD_06150	ENOG4105DC7	peptidase M24
HCD_06180	ENOG4105D7V	transposase
HCD_06185	ENOG4108RS6	transposase
HCD_06195	ENOG4105EUU	Sel1 domain protein repeat-containing protein
HCD_06210	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HCD_06235	ENOG4108RMU	ferritin dps family protein
HCD_06240	ENOG4107TUY	Histidine kinase
HCD_06270	ENOG4108VCT	Sulfite exporter TauE/SafE
HCD_06300	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HCD_06305	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HCD_06310	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HCD_06330	ENOG4108VYJ	response regulator receiver protein
HCD_06340	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HCD_06350	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HCD_06355	ENOG4105C59	p-type ATPase
HCD_06395	ENOG4105D9G	High-affinity
HCD_06415	ENOG4105BZ1	(ABC) transporter
HCD_06425	ENOG4105CXT	aspartate transcarbamylase
HCD_06435	ENOG4105DX0	Hemolysin A
HCD_06440	ENOG4105DTN	riboflavin biosynthesis protein ribF
HCD_06445	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HCD_06455	ENOG4105CNU	cell division protein FtsK
HCD_06460	ENOG4105CSH	Transporter
HCD_06465	ENOG4108JQA	flagellar
HCD_06475	ENOG4108RCM	Nitroreductase
HCD_06480	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HCD_06485	ENOG4105EI2	Pseudouridine synthase
HCD_06490	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HCD_06500	ENOG4105EGD	dinuclear metal center protein, YbgI family
HCD_06510	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HCD_06535	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HCD_06540	ENOG4108KQY	
HCD_06555	ENOG4108KQY	
HCD_06575	ENOG4105D5G	Transposase
HCD_06590	ENOG4105CQS	hydrogenase expression formation protein HypD
HCD_06595	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
HCD_06600	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HCD_06610	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HCD_06615	ENOG4105C6K	Malic enzyme
HCD_06625	ENOG4105W00	Flagellar hook capping protein
HCD_06630	ENOG4105BZE	flagellar hook protein, FlgE
HCD_06630	ENOG4105BZE	flagellar hook protein, FlgE
HCD_06660	ENOG4108F1U	ABC transporter
HCD_06665	ENOG4108I9K	permease protein
HCD_06670	ENOG4105E1F	short-chain dehydrogenase reductase
HCD_06705	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HCD_06715	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HCD_06720	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HCD_06725	ENOG41090A1	ferritin
HCD_06730	ENOG4105EAC	phosphoserine phosphatase
HCD_06750	ENOG4108IJ0	Aspartate ammonia-lyase
HCD_06765	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HCD_06770	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HCD_06775	ENOG41067XK	integral membrane protein
HCD_06785	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HCD_06795	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HCD_06800	ENOG4107UUH	Aminotransferase
HCD_06805	ENOG4108ZAI	phosphatidylglycerophosphatase a
HCD_06810	ENOG4105CPF	Cell wall formation (By similarity)
HCD_06820	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HCD_06830	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HCD_06835	ENOG4105CNI	cell division protein FtsW
HCD_06840	ENOG4105C34	Pseudouridine synthase
HCD_06850	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HCD_06855	ENOG4105CAK	Cell division ATP-binding protein ftsE
HCD_06870	ENOG4105UQX	Mate efflux family protein
HCD_06875	ENOG4105D3Y	Na H antiporter
HCD_06900	ENOG4107TPX	flagellar hook-associated
HCD_06925	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCD_06950	ENOG4105D00	flagellar biosynthetic protein flhB
HCD_06955	ENOG4107QIJ	Aconitate hydratase 2
HCD_06980	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HCD_06990	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HCD_06995	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HCD_07005	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HCD_07010	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HCD_07015	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HCD_07020	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HCD_07025	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HCD_07065	ENOG4105CRQ	synthase (Component I)
HCD_07080	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HCD_07100	ENOG4106032	Glutathionylspermidine synthase
HCD_07105	ENOG4108UHV	Lipoprotein
HCD_07120	ENOG4105CHH	sulfate transporter
HCD_07130	ENOG4105VSH	4-oxalocrotonate tautomerase
HCD_07135	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HCD_07135	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HCD_07160	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCD_07165	ENOG4108JQ7	(ABC) transporter
HCD_07170	ENOG4105C3U	ABC transporter
HCD_07175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HCD_07180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HCD_07185	ENOG4105DEF	Extracellular solute-binding protein, family 5
HCD_07190	ENOG4105K46	50S ribosomal protein l27
HCD_07220	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HCD_07250	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HCD_07255	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HCD_07260	ENOG4105D64	Mechanosensitive ion channel
HCD_07270	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HCD_07275	ENOG4105BZE	flagellar hook protein, FlgE
HCD_07305	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HCD_07315	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HCD_07320	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HCD_07330	ENOG4105M8F	Biopolymer transport protein exbD tolR
HCD_07335	ENOG4105E02	MotA TolQ exbB proton channel
HCD_07350	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HCD_07360	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HCD_07365	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HCD_07375	ENOG4105FA0	parb-like partition protein
HCD_07380	ENOG4107QJE	Chromosome Partitioning Protein
HCD_07385	ENOG4108EKN	Biotin protein ligase C terminal domain
HCD_07425	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HCD_07435	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HCD_07440	ENOG4105C25	Primosomal protein n'
HCD_07460	ENOG4105D7V	transposase
HCD_07465	ENOG4108RS6	transposase
HCD_07470	ENOG4105NI8	Cytosine-specific methyltransferase
HCD_07475	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HCD_07495	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HCD_07500	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HCD_07515	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HCD_07525	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HCD_07535	ENOG4105CRE	cytochrome C
HCD_07620	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HCD_07640	ENOG4108EHY	type IV secretion system
HCD_07700	ENOG4105WMR	Protein CrcB homolog
HCD_07705	ENOG4105CSA	Coproporphyrinogen iii oxidase
HCD_07710	ENOG4105Z0F	Cytochrome
HCD_07715	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HCD_07720	ENOG4105CFH	Aspartokinase
HCD_07735	ENOG4105EEI	dihydropteroate synthase
HCD_07750	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HCD_07755	ENOG4105C44	Serine transporter
HCD_07760	ENOG4105EJQ	L-serine dehydratase
HCD_07770	ENOG4105D7V	transposase
HCD_07775	ENOG4108RS6	transposase
HCD_07790	ENOG4105D7V	transposase
HCD_07795	ENOG4108RS6	transposase
HCD_07820	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HCD_07830	ENOG4105II7	pyrroline-5-carboxylate reductase
HCD_07845	ENOG4108RS6	transposase
HCD_07850	ENOG4105D7V	transposase
HCD_07865	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HCD_07870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCD_07885	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HCD_07935	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HCD_07940	ENOG4105D7V	transposase
HCD_07945	ENOG4108RS6	transposase
HCD_07980	ENOG4105DQ4	alcohol dehydrogenase
HCD_08000	ENOG4105EJ5	oxidoreductase gamma subunit
HCD_08010	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HCD_08015	ENOG4105DDK	oxidoreductase, beta subunit
HCD_08020	ENOG4107QTF	adenylosuccinate lyase
HCD_08030	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HCD_08035	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HCD_08040	ENOG4105C8P	)-transporter
HCD_08045	ENOG4105KNE	Phosphatidate cytidylyltransferase
HCD_08070	ENOG4105D5G	Transposase
HCD_08090	ENOG4108RS6	transposase
HCD_08095	ENOG4105D7V	transposase
HCD_08120	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HCD_08150	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HCD_08160	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HCD_08170	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HCD_08175	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HCD_08205	ENOG410695F	Crispr-associated protein, Csm1 family
HCD_08210	ENOG410695F	Crispr-associated protein, Csm1 family
HCD_08235	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HCD_08240	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HCD_08245	ENOG4105D82	Glutamate dehydrogenase
HCD_08250	ENOG4105KIS	phospholipid-binding protein
HCD_08275	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HCD_08280	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HCD_08325	ENOG4108RS6	transposase
HCD_08330	ENOG4105D7V	transposase
HCD_08375	ENOG4107QJE	Chromosome Partitioning Protein
HCD_08420	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HCD_08425	ENOG4105CZV	ABC transporter
HCD_08435	ENOG4108730	Sel1 domain protein repeat-containing protein
HCD_08440	ENOG4108UHU	Aldolase
HCD_08445	ENOG4105C01	Dihydroxy-acid dehydratase
HCD_08450	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HCD_08455	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HCD_08480	ENOG4107QP8	phosphohexose isomerase
HCD_08490	ENOG4105D22	carbon starvation protein
HCD_08495	ENOG4105E5Q	amino acid AbC transporter
HCD_08500	ENOG4105E5Q	amino acid AbC transporter
HCD_08505	ENOG4105CDA	abc transporter atp-binding protein
HCD_08510	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HCD_08530	ENOG4105EDR	glucose galactose transporter
HCD_08535	ENOG4105C7N	Xanthine uracil vitamin C permease
HCD_08555	ENOG4105C45	hydrogenase expression formation protein (HypE)
HCD_08605	ENOG4105CGA	flagellar basal-body rod protein FlgG
HCD_08640	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
HCD_08729	ENOG4105D7V	transposase
HCD_08734	ENOG4108RS6	transposase
HCD_08764	ENOG4105D7V	transposase
HCD_08769	ENOG4108RS6	transposase