locus-tag	class	description
HCD_00005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCD_00010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HCD_00015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HCD_00020	COG0288	reversible hydration of carbon dioxide
HCD_00060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HCD_00105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCD_00120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HCD_00125	COG0589	response to stress
HCD_00130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HCD_00140	COG0538	isocitrate dehydrogenase activity
HCD_00145	COG0372	Belongs to the citrate synthase family
HCD_00155	COG2194	sulfuric ester hydrolase activity
HCD_00160	COG0671	phosphoesterase, PA-phosphatase related
HCD_00170	COG0745	RESPONSE REGULATOR receiver
HCD_00200	COG0482	sulfurtransferase activity
HCD_00205	COG0358	DNA primase activity
HCD_00225	COG3328	transposase activity
HCD_00255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCD_00290	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HCD_00295	COG0149	triose-phosphate isomerase activity
HCD_00305	COG1053	succinate dehydrogenase
HCD_00310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HCD_00315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCD_00335	COG0629	single-stranded DNA binding
HCD_00340	COG0360	Binds together with S18 to 16S ribosomal RNA
HCD_00345	COG1466	dna polymerase III delta subunit
HCD_00350	COG0557	exoribonuclease II activity
HCD_00355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCD_00365	COG4174	ABC transporter (Permease)
HCD_00370	COG4166	transmembrane transport
HCD_00375	COG0180	Tryptophanyl-tRNA synthetase
HCD_00385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HCD_00390	COG0233	cytoplasmic translational termination
HCD_00405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCD_00410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCD_00415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCD_00450	COG0839	Belongs to the complex I subunit 6 family
HCD_00460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HCD_00465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HCD_00470	COG1007	ATP synthesis coupled electron transport
HCD_00505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCD_00540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCD_00545	COG0512	Glutamine amidotransferase of anthranilate synthase
HCD_00550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCD_00555	COG0134	indole-3-glycerol-phosphate synthase activity
HCD_00555	COG0135	phosphoribosylanthranilate isomerase activity
HCD_00560	COG0133	tryptophan synthase activity
HCD_00645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HCD_00650	COG0799	negative regulation of ribosome biogenesis
HCD_00655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCD_00685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HCD_00690	COG1987	bacterial-type flagellum assembly
HCD_00695	COG1157	protein secretion by the type III secretion system
HCD_00700	COG4962	Type ii secretion system protein e
HCD_00705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCD_00710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HCD_00740	COG0517	IMP dehydrogenase activity
HCD_00740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HCD_00770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCD_00775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HCD_00785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HCD_00790	COG0811	peptide transport
HCD_00795	COG0848	biopolymer transport protein
HCD_00805	COG0594	ribonuclease P activity
HCD_00815	COG0706	membrane insertase activity
HCD_00825	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCD_00855	COG0616	signal peptide processing
HCD_00860	COG0788	formyltetrahydrofolate deformylase activity
HCD_00885	COG3118	belongs to the thioredoxin family
HCD_01015	COG0675	Transposase, IS605 OrfB family
HCD_01020	COG1943	Transposase
HCD_01045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HCD_01085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HCD_01090	COG1137	ATPase activity
HCD_01100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCD_01105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HCD_01110	COG0252	asparaginase activity
HCD_01125	COG2855	membrane
HCD_01130	COG1279	arginine transmembrane transporter activity
HCD_01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCD_01145	COG0617	tRNA 3'-terminal CCA addition
HCD_01170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HCD_01175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HCD_01180	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HCD_01185	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HCD_01190	COG1943	Transposase
HCD_01195	COG0675	Transposase, IS605 OrfB family
HCD_01200	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HCD_01205	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HCD_01235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HCD_01250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCD_01255	COG0840	transmembrane signaling receptor activity
HCD_01260	COG0156	8-amino-7-oxononanoate synthase activity
HCD_01265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HCD_01300	COG1013	pyruvate-flavodoxin oxidoreductase activity
HCD_01305	COG0674	pyruvate-flavodoxin oxidoreductase activity
HCD_01305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HCD_01325	COG1918	ferrous iron import across plasma membrane
HCD_01330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCD_01335	COG1776	CheC inhibitor of MCP methylation
HCD_01335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCD_01350	COG0418	dihydroorotase activity
HCD_01370	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HCD_01375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCD_01380	COG0681	Belongs to the peptidase S26 family
HCD_01385	COG1994	Peptidase M50
HCD_01390	COG0698	ribose 5-phosphate isomerase
HCD_01400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCD_01405	COG0586	Pfam SNARE associated Golgi protein
HCD_01415	COG0012	GTP binding
HCD_01425	COG0628	permease
HCD_01455	COG1028	Short-chain dehydrogenase reductase Sdr
HCD_01460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCD_01465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HCD_01490	COG0736	holo-[acyl-carrier-protein] synthase activity
HCD_01495	COG1580	Controls the rotational direction of flagella during chemotaxis
HCD_01525	COG0187	DNA topoisomerase II activity
HCD_01530	COG0592	DNA-directed DNA polymerase activity
HCD_01540	COG0733	neurotransmitter:sodium symporter activity
HCD_01545	COG0733	neurotransmitter:sodium symporter activity
HCD_01550	COG0733	neurotransmitter:sodium symporter activity
HCD_01555	COG0824	Thioesterase
HCD_01590	COG0724	RNA recognition motif
HCD_01600	COG0517	IMP dehydrogenase activity
HCD_01600	COG0516	GMP reductase activity
HCD_01610	COG0237	dephospho-CoA kinase activity
HCD_01615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCD_01625	COG1160	GTP binding
HCD_01630	COG0776	regulation of translation
HCD_01650	COG1086	Polysaccharide biosynthesis protein
HCD_01655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCD_01685	COG1083	cytidylyl-transferase
HCD_01695	COG2089	acid synthase
HCD_01700	COG0352	thiamine-phosphate diphosphorylase activity
HCD_01705	COG0351	phosphomethylpyrimidine kinase
HCD_01720	COG0488	(ABC) transporter
HCD_01725	COG1943	Transposase
HCD_01735	COG0675	Transposase, IS605 OrfB family
HCD_01760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HCD_01765	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HCD_01765	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HCD_01770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HCD_01775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HCD_01800	COG0756	dUTP diphosphatase activity
HCD_01820	COG0375	protein maturation
HCD_01825	COG1749	Flagellar hook protein flgE
HCD_01830	COG2824	Alkylphosphonate utilization operon protein PhnA
HCD_01845	COG0753	catalase activity
HCD_01890	COG0728	peptidoglycan biosynthetic process
HCD_01955	COG0675	Transposase, IS605 OrfB family
HCD_01960	COG1943	Transposase
HCD_01970	COG1757	Na H antiporter
HCD_01975	COG0251	oxidation-reduction process
HCD_01980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HCD_01985	COG1115	amino acid carrier protein
HCD_01990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCD_01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HCD_02000	COG0765	amino acid transport
HCD_02030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCD_02040	COG1058	Belongs to the CinA family
HCD_02040	COG1546	Belongs to the CinA family
HCD_02045	COG1136	(ABC) transporter
HCD_02075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCD_02080	COG1766	The M ring may be actively involved in energy transduction
HCD_02085	COG0671	phosphoesterase, PA-phosphatase related
HCD_02090	COG0504	CTP synthase activity
HCD_02095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HCD_02095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HCD_02100	COG0564	pseudouridine synthase activity
HCD_02125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HCD_02130	COG2894	cell division
HCD_02140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HCD_02145	COG1663	tetraacyldisaccharide 4'-kinase activity
HCD_02150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCD_02155	COG3980	spore coat polysaccharide biosynthesis protein
HCD_02160	COG3980	spore coat polysaccharide biosynthesis protein
HCD_02165	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HCD_02200	COG0748	coenzyme F420 binding
HCD_02215	COG0675	Transposase, IS605 OrfB family
HCD_02220	COG1943	Transposase
HCD_02225	COG1192	Involved in chromosome partitioning
HCD_02285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCD_02290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCD_02300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCD_02310	COG0343	queuine tRNA-ribosyltransferase activity
HCD_02320	COG0859	PFAM glycosyl transferase family 9
HCD_02325	COG0248	Ppx GppA phosphatase
HCD_02330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HCD_02335	COG0134	indole-3-glycerol-phosphate synthase activity
HCD_02345	COG0727	PFAM Uncharacterised protein family (UPF0153)
HCD_02380	COG0402	S-adenosylhomocysteine deaminase activity
HCD_02385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HCD_02390	COG0785	Cytochrome C biogenesis protein
HCD_02395	COG0542	response to heat
HCD_02410	COG0675	Transposase, IS605 OrfB family
HCD_02415	COG1943	Transposase
HCD_02430	COG3550	peptidyl-serine autophosphorylation
HCD_02435	COG4974	Belongs to the 'phage' integrase family
HCD_02470	COG0489	protein tyrosine kinase activity
HCD_02475	COG1943	Transposase
HCD_02485	COG0675	Transposase, IS605 OrfB family
HCD_02505	COG2226	methyltransferase
HCD_02510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HCD_02515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCD_02525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCD_02540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HCD_02545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCD_02555	COG1570	exodeoxyribonuclease VII activity
HCD_02560	COG0750	zinc metalloprotease
HCD_02590	COG4239	(ABC) transporter, permease
HCD_02595	COG4172	Belongs to the ABC transporter superfamily
HCD_02635	COG0537	adenosine 5'-monophosphoramidase activity
HCD_02645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCD_02645	COG0072	phenylalanine-tRNA ligase activity
HCD_02650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HCD_02660	COG0539	negative regulation of cytoplasmic translation
HCD_02660	COG1185	polyribonucleotide nucleotidyltransferase activity
HCD_02670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HCD_02675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HCD_02680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCD_02690	COG0835	chemotaxis
HCD_02690	COG0784	Response regulator, receiver
HCD_02695	COG2198	Histidine kinase
HCD_02695	COG0643	Histidine kinase
HCD_02730	COG4221	oxidoreductase activity
HCD_02750	COG0813	purine-nucleoside phosphorylase activity
HCD_02760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCD_02765	COG2814	Major facilitator Superfamily
HCD_02770	COG0037	tRNA processing
HCD_02775	COG0475	glutathione-regulated potassium exporter activity
HCD_02775	COG0569	domain protein
HCD_02790	COG2897	thiosulfate sulfurtransferase activity
HCD_02795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCD_02805	COG0859	PFAM glycosyl transferase family 9
HCD_02810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HCD_02820	COG0675	Transposase, IS605 OrfB family
HCD_02825	COG1943	Transposase
HCD_02830	COG0556	nucleotide-excision repair
HCD_02855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCD_02860	COG0049	tRNA binding
HCD_02870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCD_02870	COG0085	RNA polymerase activity
HCD_02875	COG0222	ribosome binding
HCD_02885	COG0081	regulation of translation
HCD_02890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCD_02895	COG0250	Participates in transcription elongation, termination and antitermination
HCD_02910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCD_02915	COG1132	(ABC) transporter
HCD_02940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCD_02955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HCD_02965	COG0151	Belongs to the GarS family
HCD_02975	COG0675	Transposase, IS605 OrfB family
HCD_02980	COG1943	Transposase
HCD_03020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HCD_03030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HCD_03035	COG1136	(ABC) transporter
HCD_03040	COG2089	acid synthase
HCD_03050	COG0191	fructose-bisphosphate aldolase activity
HCD_03055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HCD_03070	COG0303	'Molybdopterin
HCD_03110	COG0113	porphobilinogen synthase activity
HCD_03115	COG0217	transcriptional regulatory protein
HCD_03120	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HCD_03160	COG0148	phosphopyruvate hydratase activity
HCD_03165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCD_03215	COG3278	Belongs to the heme-copper respiratory oxidase family
HCD_03220	COG0471	metal ion transport
HCD_03225	COG1194	a g-specific adenine glycosylase
HCD_03235	COG1620	l-lactate permease
HCD_03240	COG1620	l-lactate permease
HCD_03245	COG0247	lactate metabolic process
HCD_03250	COG1139	Iron-sulfur cluster binding protein
HCD_03260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HCD_03295	COG0424	maF-like protein
HCD_03300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCD_03330	COG0505	Belongs to the CarA family
HCD_03345	COG0697	spore germination
HCD_03380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCD_03385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCD_03390	COG0574	Belongs to the PEP-utilizing enzyme family
HCD_03390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCD_03430	COG1420	regulation of RNA biosynthetic process
HCD_03450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCD_03455	COG0551	DNA topoisomerase type I activity
HCD_03455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCD_03460	COG0731	radical SAM domain protein
HCD_03475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCD_03485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HCD_03495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCD_03505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HCD_03510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCD_03515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCD_03525	COG0579	oxidoreductase
HCD_03545	COG0840	transmembrane signaling receptor activity
HCD_03565	COG0268	Binds directly to 16S ribosomal RNA
HCD_03575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCD_03580	COG0832	Belongs to the urease beta subunit family
HCD_03580	COG0831	urea catabolic process
HCD_03585	COG0804	urea catabolic process
HCD_03600	COG0830	nickel cation binding
HCD_03605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HCD_03610	COG0829	nickel cation binding
HCD_03665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCD_03670	COG0671	phosphoesterase, PA-phosphatase related
HCD_03690	COG2011	ABC-type metal ion transport system permease component
HCD_03695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCD_03705	COG0307	riboflavin synthase, alpha
HCD_03710	COG0084	hydrolase, TatD family'
HCD_03720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HCD_03725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HCD_03740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HCD_03750	COG0768	penicillin binding
HCD_03760	COG0450	alkyl hydroperoxide reductase
HCD_03770	COG0772	Belongs to the SEDS family
HCD_03790	COG0768	penicillin binding
HCD_03800	COG1106	Psort location Cytoplasmic, score
HCD_03810	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HCD_03825	COG0723	plastoquinol--plastocyanin reductase activity
HCD_03830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCD_03840	COG0739	heme binding
HCD_03850	COG0285	dihydrofolate synthase activity
HCD_03860	COG0495	leucyl-tRNA aminoacylation
HCD_03870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCD_03875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCD_03880	COG1862	Preprotein translocase
HCD_03890	COG1074	ATP-dependent DNA helicase activity
HCD_03900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCD_03930	COG0500	methyltransferase
HCD_03940	COG0203	ribosomal protein L17
HCD_03945	COG0202	RNA polymerase activity
HCD_03950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCD_03955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCD_03960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCD_03975	COG0024	Methionine aminopeptidase
HCD_03980	COG0201	protein transport
HCD_03985	COG0200	Binds to the 23S rRNA
HCD_04020	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCD_04025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCD_04030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCD_04050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCD_04075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCD_04080	COG0051	transcription antitermination factor activity, RNA binding
HCD_04095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCD_04100	COG0114	fumarate hydratase activity
HCD_04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCD_04125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCD_04145	COG0732	type I restriction modification DNA specificity domain
HCD_04150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HCD_04170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCD_04170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HCD_04180	COG0305	Participates in initiation and elongation during chromosome replication
HCD_04220	COG0157	Belongs to the NadC ModD family
HCD_04245	COG0793	Belongs to the peptidase S41A family
HCD_04255	COG0204	Acyl-transferase
HCD_04260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCD_04265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HCD_04270	COG0126	phosphoglycerate kinase activity
HCD_04275	COG0598	Magnesium transport protein CorA
HCD_04280	COG0861	Integral membrane protein TerC family
HCD_04315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCD_04320	COG0163	prenyltransferase activity
HCD_04330	COG0210	DNA helicase
HCD_04340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCD_04355	COG2226	methyltransferase
HCD_04365	COG1739	Uncharacterized protein family UPF0029
HCD_04380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCD_04390	COG1253	flavin adenine dinucleotide binding
HCD_04395	COG0306	phosphate transporter
HCD_04400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HCD_04410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCD_04415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCD_04475	COG2217	Heavy metal translocating P-type atpase
HCD_04475	COG2608	mercury ion transmembrane transporter activity
HCD_04485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCD_04485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCD_04490	COG0786	glutamate:sodium symporter activity
HCD_04500	COG0348	domain, Protein
HCD_04505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HCD_04535	COG0195	Participates in both transcription termination and antitermination
HCD_04575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCD_04590	COG0708	Exodeoxyribonuclease III
HCD_04625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HCD_04640	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HCD_04665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCD_04665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCD_04675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HCD_04700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HCD_04705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HCD_04725	COG0497	DNA recombination
HCD_04730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCD_04745	COG0840	transmembrane signaling receptor activity
HCD_04750	COG1064	alcohol dehydrogenase
HCD_04755	COG0686	Belongs to the AlaDH PNT family
HCD_04760	COG0833	amino acid
HCD_04765	COG0010	Belongs to the arginase family
HCD_04775	COG0280	phosphate acetyltransferase
HCD_04775	COG0281	malic enzyme
HCD_04795	COG0287	Prephenate dehydrogenase
HCD_04800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HCD_04805	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HCD_04810	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCD_04825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCD_04830	COG1077	Cell shape determining protein MreB Mrl
HCD_04850	COG1687	branched-chain amino acid
HCD_04855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HCD_04860	COG0484	heat shock protein binding
HCD_04870	COG0482	sulfurtransferase activity
HCD_04890	COG0811	peptide transport
HCD_04895	COG0848	biopolymer transport protein
HCD_04900	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCD_04920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HCD_04925	COG1295	ribonuclease BN
HCD_04935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HCD_04940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCD_04960	COG2990	Protein conserved in bacteria
HCD_04970	COG0587	DNA-directed DNA polymerase activity
HCD_04975	COG1187	pseudouridine synthase activity
HCD_05050	COG3657	addiction module killer protein
HCD_05070	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCD_05075	COG2404	hydrolase activity, acting on ester bonds
HCD_05080	COG0745	RESPONSE REGULATOR receiver
HCD_05085	COG1408	metallophosphoesterase
HCD_05105	COG1943	Transposase
HCD_05110	COG0675	Transposase, IS605 OrfB family
HCD_05125	COG2204	response regulator
HCD_05135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCD_05140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HCD_05155	COG0675	Transposase, IS605 OrfB family
HCD_05160	COG1943	Transposase
HCD_05180	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HCD_05185	COG0675	Transposase, IS605 OrfB family
HCD_05190	COG1943	Transposase
HCD_05205	COG1338	Plays a role in the flagellum-specific transport system
HCD_05210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCD_05215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCD_05225	COG0730	response to heat
HCD_05240	COG4974	Belongs to the 'phage' integrase family
HCD_05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HCD_05280	COG0328	RNA-DNA hybrid ribonuclease activity
HCD_05290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HCD_05295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCD_05305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HCD_05310	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HCD_05315	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HCD_05330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HCD_05360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCD_05370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCD_05390	COG0243	molybdopterin cofactor binding
HCD_05400	COG0437	4 iron, 4 sulfur cluster binding
HCD_05420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCD_05425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCD_05430	COG0254	rRNA binding
HCD_05435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCD_05455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCD_05475	COG0174	glutamine synthetase
HCD_05495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HCD_05515	COG0277	FAD linked oxidase domain protein
HCD_05530	COG0741	lytic transglycosylase activity
HCD_05530	COG0739	heme binding
HCD_05530	COG1196	nuclear chromosome segregation
HCD_05535	COG0709	Synthesizes selenophosphate from selenide and ATP
HCD_05555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HCD_05565	COG4591	ABC-type transport system involved in lipoprotein release permease component
HCD_05590	COG2217	Heavy metal translocating P-type atpase
HCD_05595	COG0606	chelatase, subunit chli
HCD_05600	COG0242	peptide deformylase activity
HCD_05610	COG0544	peptidyl-prolyl cis-trans isomerase activity
HCD_05620	COG0348	domain, Protein
HCD_05625	COG0437	4 iron, 4 sulfur cluster binding
HCD_05630	COG0243	molybdopterin cofactor binding
HCD_05645	COG0521	Mo-molybdopterin cofactor biosynthetic process
HCD_05650	COG0314	molybdopterin synthase activity
HCD_05660	COG0303	'Molybdopterin
HCD_05675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCD_05675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCD_05690	COG3842	ATPase activity
HCD_05710	COG2171	N-acyltransferase activity
HCD_05720	COG0436	Aminotransferase
HCD_05735	COG1193	negative regulation of DNA recombination
HCD_05745	COG0492	ferredoxin-NADP+ reductase activity
HCD_05750	COG3118	belongs to the thioredoxin family
HCD_05755	COG0792	nuclease activity
HCD_05760	COG0460	homoserine dehydrogenase
HCD_05805	COG1360	Flagellar Motor Protein
HCD_05810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HCD_05815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HCD_05865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HCD_05870	COG0670	Belongs to the BI1 family
HCD_05875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HCD_05890	COG1942	4-Oxalocrotonate Tautomerase
HCD_05900	COG0585	pseudouridine synthase activity
HCD_05905	COG0501	Belongs to the peptidase M48B family
HCD_05910	COG0302	gtp cyclohydrolase
HCD_05915	COG0142	geranyltranstransferase activity
HCD_05930	COG0720	synthase
HCD_05935	COG0602	queuosine metabolic process
HCD_06020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCD_06025	COG0167	dihydroorotate dehydrogenase activity
HCD_06040	COG1028	Short-chain dehydrogenase reductase Sdr
HCD_06055	COG0833	amino acid
HCD_06070	COG0745	RESPONSE REGULATOR receiver
HCD_06085	COG0484	heat shock protein binding
HCD_06090	COG0789	Transcriptional regulator
HCD_06095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HCD_06095	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HCD_06100	COG0735	belongs to the Fur family
HCD_06115	COG1776	CheC inhibitor of MCP methylation
HCD_06115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCD_06120	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCD_06125	COG1191	sigma factor activity
HCD_06135	COG0455	bacterial-type flagellum organization
HCD_06140	COG1419	protein localization to endoplasmic reticulum
HCD_06145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCD_06150	COG0006	proline dipeptidase activity
HCD_06180	COG0675	Transposase, IS605 OrfB family
HCD_06185	COG1943	Transposase
HCD_06195	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HCD_06210	COG0442	prolyl-tRNA aminoacylation
HCD_06235	COG0783	Belongs to the Dps family
HCD_06245	COG3951	Flagellar rod assembly protein muramidase FlgJ
HCD_06270	COG0730	response to heat
HCD_06300	COG0805	protein transport
HCD_06305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCD_06310	COG0357	Ribosomal RNA small subunit methyltransferase G
HCD_06340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCD_06350	COG1183	phosphatidylcholine synthase activity
HCD_06360	COG2608	mercury ion transmembrane transporter activity
HCD_06365	COG2608	mercury ion transmembrane transporter activity
HCD_06395	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HCD_06415	COG1132	(ABC) transporter
HCD_06425	COG0540	Belongs to the ATCase OTCase family
HCD_06435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HCD_06440	COG0196	riboflavin kinase activity
HCD_06445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCD_06455	COG1674	ftsk spoiiie
HCD_06460	COG0477	Major facilitator Superfamily
HCD_06465	COG4786	Flagellar basal body rod
HCD_06475	COG0778	Nitroreductase
HCD_06480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCD_06485	COG0564	pseudouridine synthase activity
HCD_06490	COG1519	Transferase
HCD_06500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCD_06510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HCD_06535	COG4974	Belongs to the 'phage' integrase family
HCD_06540	COG3550	peptidyl-serine autophosphorylation
HCD_06555	COG3550	peptidyl-serine autophosphorylation
HCD_06575	COG3328	transposase activity
HCD_06590	COG0409	Hydrogenase expression formation protein
HCD_06595	COG0298	carbon dioxide binding
HCD_06600	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HCD_06610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCD_06615	COG0280	phosphate acetyltransferase
HCD_06625	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HCD_06660	COG1120	ATPase activity
HCD_06665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCD_06670	COG0300	oxidoreductase activity
HCD_06675	COG1607	acyl-coa hydrolase
HCD_06705	COG0751	glycine-tRNA ligase activity
HCD_06715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCD_06720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCD_06725	COG1528	Iron-storage protein
HCD_06730	COG0560	Phosphoserine phosphatase
HCD_06750	COG1027	Aspartate ammonia-lyase
HCD_06775	COG0762	integral membrane protein
HCD_06785	COG0037	tRNA processing
HCD_06795	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HCD_06800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HCD_06805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HCD_06810	COG1181	Belongs to the D-alanine--D-alanine ligase family
HCD_06820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HCD_06830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCD_06835	COG0772	Belongs to the SEDS family
HCD_06840	COG0564	pseudouridine synthase activity
HCD_06850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HCD_06855	COG2884	Cell division ATP-binding protein ftsE
HCD_06870	COG0534	Mate efflux family protein
HCD_06875	COG2056	Na+-H+ antiporter family
HCD_06900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HCD_06925	COG0552	protein localization to endoplasmic reticulum
HCD_06950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCD_06955	COG1049	propionate catabolic process, 2-methylcitrate cycle
HCD_06980	COG0860	N-Acetylmuramoyl-L-alanine amidase
HCD_06990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCD_07000	COG1758	RNA polymerase activity
HCD_07005	COG0528	UMP kinase activity
HCD_07010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HCD_07015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HCD_07020	COG0849	cell division
HCD_07025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCD_07065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCD_07080	COG0019	diaminopimelate decarboxylase activity
HCD_07100	COG0754	glutathionylspermidine amidase activity
HCD_07120	COG0659	secondary active sulfate transmembrane transporter activity
HCD_07130	COG1942	4-Oxalocrotonate Tautomerase
HCD_07160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCD_07165	COG4608	Belongs to the ABC transporter superfamily
HCD_07170	COG0444	Belongs to the ABC transporter superfamily
HCD_07175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCD_07180	COG0601	transmembrane transport
HCD_07185	COG0747	negative chemotaxis
HCD_07190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HCD_07220	COG1166	arginine decarboxylase activity
HCD_07250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCD_07250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCD_07255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HCD_07260	COG0668	transmembrane transport
HCD_07270	COG0405	Gamma-glutamyltransferase
HCD_07305	COG1047	Peptidyl-prolyl cis-trans
HCD_07315	COG2885	chlorophyll binding
HCD_07320	COG0823	Involved in the tonB-independent uptake of proteins
HCD_07330	COG0848	biopolymer transport protein
HCD_07335	COG0811	peptide transport
HCD_07350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCD_07360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCD_07365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCD_07375	COG1475	DNA binding
HCD_07380	COG1192	Involved in chromosome partitioning
HCD_07425	COG0326	Molecular chaperone. Has ATPase activity
HCD_07435	COG3043	anaerobic respiration
HCD_07440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCD_07460	COG0675	Transposase, IS605 OrfB family
HCD_07465	COG1943	Transposase
HCD_07475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HCD_07495	COG0439	Biotin carboxylase
HCD_07500	COG0511	ligase activity, forming carbon-carbon bonds
HCD_07515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HCD_07525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HCD_07535	COG1333	cytochrome c biogenesis protein
HCD_07535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HCD_07545	COG3177	Filamentation induced by cAMP protein fic
HCD_07580	COG3177	Filamentation induced by cAMP protein fic
HCD_07620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCD_07640	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
HCD_07670	COG3451	type IV secretory pathway VirB4
HCD_07700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCD_07705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HCD_07710	COG2863	cytochrome
HCD_07715	COG0494	nUDIX hydrolase
HCD_07720	COG0527	aspartate kinase activity
HCD_07735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCD_07750	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HCD_07755	COG0814	amino acid
HCD_07760	COG1760	l-serine dehydratase
HCD_07770	COG0675	Transposase, IS605 OrfB family
HCD_07775	COG1943	Transposase
HCD_07790	COG0675	Transposase, IS605 OrfB family
HCD_07795	COG1943	Transposase
HCD_07805	COG0492	ferredoxin-NADP+ reductase activity
HCD_07820	COG0716	FMN binding
HCD_07830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCD_07845	COG1943	Transposase
HCD_07850	COG0675	Transposase, IS605 OrfB family
HCD_07860	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCD_07865	COG0525	valine-tRNA ligase activity
HCD_07870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCD_07885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCD_07935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCD_07940	COG0675	Transposase, IS605 OrfB family
HCD_07945	COG1943	Transposase
HCD_07980	COG1064	alcohol dehydrogenase
HCD_08000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HCD_08010	COG0674	pyruvate-flavodoxin oxidoreductase activity
HCD_08015	COG1013	pyruvate-flavodoxin oxidoreductase activity
HCD_08020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCD_08030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HCD_08035	COG0445	tRNA wobble uridine modification
HCD_08040	COG0471	metal ion transport
HCD_08045	COG0575	Belongs to the CDS family
HCD_08070	COG3328	transposase activity
HCD_08090	COG1943	Transposase
HCD_08095	COG0675	Transposase, IS605 OrfB family
HCD_08120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HCD_08145	COG0850	regulation of cytokinetic process
HCD_08150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HCD_08160	COG0083	homoserine kinase activity
HCD_08170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCD_08175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCD_08205	COG1353	crispr-associated protein
HCD_08210	COG1353	crispr-associated protein
HCD_08235	COG0501	Belongs to the peptidase M48B family
HCD_08240	COG2890	protein-(glutamine-N5) methyltransferase activity
HCD_08245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HCD_08250	COG1881	PFAM PEBP family protein
HCD_08275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCD_08280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCD_08280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCD_08325	COG1943	Transposase
HCD_08330	COG0675	Transposase, IS605 OrfB family
HCD_08340	COG3177	Filamentation induced by cAMP protein fic
HCD_08360	COG4974	Belongs to the 'phage' integrase family
HCD_08375	COG1192	Involved in chromosome partitioning
HCD_08420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCD_08425	COG1131	(ABC) transporter
HCD_08435	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HCD_08440	COG0800	Aldolase
HCD_08445	COG0129	dihydroxy-acid dehydratase activity
HCD_08450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCD_08455	COG0363	glucosamine-6-phosphate deaminase activity
HCD_08480	COG0166	Belongs to the GPI family
HCD_08490	COG1966	Carbon starvation protein
HCD_08505	COG1126	abc transporter atp-binding protein
HCD_08510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HCD_08530	COG0738	Major facilitator superfamily
HCD_08535	COG2252	PERMEase
HCD_08555	COG0309	Hydrogenase expression formation protein (HypE)
HCD_08560	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HCD_08605	COG4786	Flagellar basal body rod
HCD_08640	COG4735	regulation of single-species biofilm formation
HCD_08729	COG0675	Transposase, IS605 OrfB family
HCD_08734	COG1943	Transposase
HCD_08764	COG0675	Transposase, IS605 OrfB family
HCD_08769	COG1943	Transposase