locus-tag	class	description
EG63_00005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EG63_00015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EG63_00020	COG0288	reversible hydration of carbon dioxide
EG63_00025	COG0284	orotidine-5'-phosphate decarboxylase activity
EG63_00070	COG0459	protein refolding
EG63_00085	COG0358	DNA primase activity
EG63_00090	COG0482	sulfurtransferase activity
EG63_00120	COG0784	Response regulator, receiver
EG63_00130	COG0671	phosphoesterase, PA-phosphatase related
EG63_00135	COG2194	sulfuric ester hydrolase activity
EG63_00160	COG0372	Belongs to the citrate synthase family
EG63_00165	COG0538	isocitrate dehydrogenase activity
EG63_00185	COG0589	response to stress
EG63_00190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EG63_00195	COG0542	response to heat
EG63_00245	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EG63_00265	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EG63_00270	COG2957	Belongs to the agmatine deiminase family
EG63_00285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG63_00290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EG63_00290	COG0506	proline dehydrogenase activity
EG63_00290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EG63_00385	COG0804	urea catabolic process
EG63_00400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EG63_00435	COG0840	transmembrane signaling receptor activity
EG63_00465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EG63_00470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EG63_00475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EG63_00505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG63_00515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EG63_00520	COG0840	transmembrane signaling receptor activity
EG63_00525	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EG63_00535	COG1216	Glycosyl transferase, family 2
EG63_00545	COG0737	Belongs to the 5'-nucleotidase family
EG63_00550	COG1854	S-ribosylhomocysteine lyase activity
EG63_00555	COG0626	cystathionine gamma-synthase activity
EG63_00560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EG63_00575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EG63_00580	COG1420	regulation of RNA biosynthetic process
EG63_00600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EG63_00605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG63_00605	COG0551	DNA topoisomerase type I activity
EG63_00610	COG0731	radical SAM domain protein
EG63_00620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EG63_00620	COG0574	Belongs to the PEP-utilizing enzyme family
EG63_00635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EG63_00680	COG1760	l-serine dehydratase
EG63_00685	COG0814	amino acid
EG63_00690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EG63_00700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EG63_00710	COG1139	Iron-sulfur cluster binding protein
EG63_00715	COG0247	lactate metabolic process
EG63_00720	COG1620	l-lactate permease
EG63_00725	COG1620	l-lactate permease
EG63_00730	COG1194	a g-specific adenine glycosylase
EG63_00735	COG0471	metal ion transport
EG63_00745	COG3278	Belongs to the heme-copper respiratory oxidase family
EG63_00795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EG63_00800	COG0148	phosphopyruvate hydratase activity
EG63_00830	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EG63_00840	COG0217	transcriptional regulatory protein
EG63_00845	COG0113	porphobilinogen synthase activity
EG63_00850	COG2205	protein histidine kinase activity
EG63_00885	COG0303	'Molybdopterin
EG63_00905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG63_00910	COG0191	fructose-bisphosphate aldolase activity
EG63_00925	COG2089	acid synthase
EG63_00930	COG1136	(ABC) transporter
EG63_00935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EG63_00945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EG63_00975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG63_00980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EG63_00985	COG1053	succinate dehydrogenase
EG63_01000	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EG63_01005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG63_01035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG63_01055	COG0489	protein tyrosine kinase activity
EG63_01080	COG0326	Molecular chaperone. Has ATPase activity
EG63_01085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EG63_01100	COG0471	metal ion transport
EG63_01105	COG0575	Belongs to the CDS family
EG63_01110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EG63_01115	COG1881	PFAM PEBP family protein
EG63_01130	COG1104	cysteine desulfurase activity
EG63_01145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EG63_01150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EG63_01150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EG63_01155	COG0730	response to heat
EG63_01175	COG0659	secondary active sulfate transmembrane transporter activity
EG63_01220	COG0754	glutathionylspermidine amidase activity
EG63_01235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EG63_01245	COG0181	hydroxymethylbilane synthase activity
EG63_01250	COG0442	prolyl-tRNA aminoacylation
EG63_01260	COG0142	geranyltranstransferase activity
EG63_01275	COG0783	Belongs to the Dps family
EG63_01285	COG3951	Flagellar rod assembly protein muramidase FlgJ
EG63_01310	COG4172	Belongs to the ABC transporter superfamily
EG63_01315	COG4239	(ABC) transporter, permease
EG63_01355	COG0750	zinc metalloprotease
EG63_01375	COG0542	response to heat
EG63_01380	COG0785	Cytochrome C biogenesis protein
EG63_01385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EG63_01390	COG0402	S-adenosylhomocysteine deaminase activity
EG63_01425	COG0727	PFAM Uncharacterised protein family (UPF0153)
EG63_01435	COG0134	indole-3-glycerol-phosphate synthase activity
EG63_01445	COG0248	Ppx GppA phosphatase
EG63_01450	COG0859	PFAM glycosyl transferase family 9
EG63_01480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG63_01485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG63_01505	COG0019	diaminopimelate decarboxylase activity
EG63_01520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG63_01545	COG0747	negative chemotaxis
EG63_01550	COG0601	transmembrane transport
EG63_01555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG63_01560	COG0444	Belongs to the ABC transporter superfamily
EG63_01565	COG4608	Belongs to the ABC transporter superfamily
EG63_01600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG63_01605	COG0726	polysaccharide deacetylase
EG63_01615	COG0523	cobalamin synthesis protein
EG63_01630	COG0748	coenzyme F420 binding
EG63_01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG63_01670	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EG63_01675	COG3980	spore coat polysaccharide biosynthesis protein
EG63_01680	COG3980	spore coat polysaccharide biosynthesis protein
EG63_01685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG63_01690	COG1663	tetraacyldisaccharide 4'-kinase activity
EG63_01710	COG2894	cell division
EG63_01720	COG0758	DNA mediated transformation
EG63_01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EG63_01725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EG63_01790	COG0564	pseudouridine synthase activity
EG63_01795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EG63_01795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EG63_01800	COG0504	CTP synthase activity
EG63_01810	COG1766	The M ring may be actively involved in energy transduction
EG63_01815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG63_01825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EG63_01845	COG3842	ATPase activity
EG63_01855	COG4786	Flagellar basal body rod
EG63_01860	COG0477	Major facilitator Superfamily
EG63_01865	COG1674	ftsk spoiiie
EG63_01875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EG63_01880	COG0196	riboflavin kinase activity
EG63_01885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EG63_01905	COG1132	(ABC) transporter
EG63_01920	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EG63_01935	COG2608	mercury ion transmembrane transporter activity
EG63_01945	COG1183	phosphatidylcholine synthase activity
EG63_01955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG63_01960	COG2264	protein methyltransferase activity
EG63_01990	COG0357	Ribosomal RNA small subunit methyltransferase G
EG63_01995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EG63_02000	COG0805	protein transport
EG63_02005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG63_02055	COG0083	homoserine kinase activity
EG63_02075	COG0779	Required for maturation of 30S ribosomal subunits
EG63_02085	COG1408	metallophosphoesterase
EG63_02090	COG0745	RESPONSE REGULATOR receiver
EG63_02105	COG2404	hydrolase activity, acting on ester bonds
EG63_02110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EG63_02135	COG0006	proline dipeptidase activity
EG63_02140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EG63_02145	COG1419	protein localization to endoplasmic reticulum
EG63_02150	COG0455	bacterial-type flagellum organization
EG63_02160	COG1191	sigma factor activity
EG63_02165	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG63_02170	COG1776	CheC inhibitor of MCP methylation
EG63_02170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG63_02185	COG0735	belongs to the Fur family
EG63_02190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EG63_02190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EG63_02195	COG0789	Transcriptional regulator
EG63_02200	COG0484	heat shock protein binding
EG63_02220	COG0745	RESPONSE REGULATOR receiver
EG63_02225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EG63_02225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EG63_02235	COG0833	amino acid
EG63_02240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EG63_02250	COG1028	Short-chain dehydrogenase reductase Sdr
EG63_02255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG63_02270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EG63_02295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EG63_02360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EG63_02465	COG0824	Thioesterase
EG63_02470	COG0733	neurotransmitter:sodium symporter activity
EG63_02475	COG0733	neurotransmitter:sodium symporter activity
EG63_02485	COG0592	DNA-directed DNA polymerase activity
EG63_02490	COG0187	DNA topoisomerase II activity
EG63_02505	COG1196	nuclear chromosome segregation
EG63_02505	COG0741	lytic transglycosylase activity
EG63_02505	COG0739	heme binding
EG63_02520	COG0277	FAD linked oxidase domain protein
EG63_02540	COG0174	glutamine synthetase
EG63_02555	COG0359	binds to the 23S rRNA
EG63_02560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EG63_02590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EG63_02595	COG0254	rRNA binding
EG63_02600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EG63_02605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG63_02635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG63_02645	COG1028	Short-chain dehydrogenase reductase Sdr
EG63_02675	COG0628	permease
EG63_02685	COG0012	GTP binding
EG63_02710	COG0698	ribose 5-phosphate isomerase
EG63_02715	COG1994	Peptidase M50
EG63_02720	COG0681	Belongs to the peptidase S26 family
EG63_02760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG63_02760	COG1776	CheC inhibitor of MCP methylation
EG63_02765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EG63_02770	COG1918	ferrous iron import across plasma membrane
EG63_02790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EG63_02790	COG0674	pyruvate-flavodoxin oxidoreductase activity
EG63_02795	COG1013	pyruvate-flavodoxin oxidoreductase activity
EG63_02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EG63_02835	COG0156	8-amino-7-oxononanoate synthase activity
EG63_02840	COG0840	transmembrane signaling receptor activity
EG63_02850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EG63_02865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EG63_02890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EG63_02900	COG1131	(ABC) transporter
EG63_02915	COG0745	RESPONSE REGULATOR receiver
EG63_02925	COG0563	adenylate kinase activity
EG63_02940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EG63_02945	COG1193	negative regulation of DNA recombination
EG63_02960	COG0436	Aminotransferase
EG63_02970	COG2171	N-acyltransferase activity
EG63_02990	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG63_02995	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EG63_03000	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EG63_03005	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EG63_03010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EG63_03015	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EG63_03040	COG0617	tRNA 3'-terminal CCA addition
EG63_03055	COG0778	Nitroreductase
EG63_03065	COG0762	integral membrane protein
EG63_03090	COG1027	Aspartate ammonia-lyase
EG63_03105	COG0560	Phosphoserine phosphatase
EG63_03110	COG1528	Iron-storage protein
EG63_03115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EG63_03120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EG63_03125	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EG63_03135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EG63_03150	COG0328	RNA-DNA hybrid ribonuclease activity
EG63_03170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG63_03205	COG4974	Belongs to the 'phage' integrase family
EG63_03215	COG0730	response to heat
EG63_03225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EG63_03255	COG1338	Plays a role in the flagellum-specific transport system
EG63_03265	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EG63_03275	COG0183	Belongs to the thiolase family
EG63_03280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG63_03285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG63_03290	COG2031	fatty acid transporter
EG63_03300	COG0145	ligase activity
EG63_03305	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EG63_03310	COG4647	ligase activity
EG63_03325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EG63_03330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EG63_03340	COG2204	response regulator
EG63_03350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EG63_03370	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
EG63_03390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EG63_03395	COG1137	ATPase activity
EG63_03405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EG63_03410	COG1279	arginine transmembrane transporter activity
EG63_03430	COG0252	asparaginase activity
EG63_03435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EG63_03450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EG63_03455	COG0037	tRNA processing
EG63_03480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG63_03485	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EG63_03490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EG63_03495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EG63_03510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EG63_03520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EG63_03550	COG0564	pseudouridine synthase activity
EG63_03560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EG63_03565	COG2884	Cell division ATP-binding protein ftsE
EG63_03585	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EG63_03615	COG2056	Na+-H+ antiporter family
EG63_03620	COG0534	Mate efflux family protein
EG63_03640	COG0552	protein localization to endoplasmic reticulum
EG63_03660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EG63_03670	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG63_03680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EG63_03690	COG1758	RNA polymerase activity
EG63_03695	COG0528	UMP kinase activity
EG63_03705	COG1049	propionate catabolic process, 2-methylcitrate cycle
EG63_03765	COG0732	type I restriction modification DNA specificity domain
EG63_03770	COG2217	Heavy metal translocating P-type atpase
EG63_03775	COG0606	chelatase, subunit chli
EG63_03805	COG0315	cyclic pyranopterin monophosphate synthase activity
EG63_03810	COG0521	Mo-molybdopterin cofactor biosynthetic process
EG63_03815	COG0314	molybdopterin synthase activity
EG63_03835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG63_03835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG63_03860	COG0736	holo-[acyl-carrier-protein] synthase activity
EG63_03865	COG1580	Controls the rotational direction of flagella during chemotaxis
EG63_03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG63_03895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EG63_03900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EG63_03905	COG1360	Flagellar Motor Protein
EG63_03915	COG1732	Glycine betaine
EG63_03920	COG1125	glycine betaine transport
EG63_03920	COG0517	IMP dehydrogenase activity
EG63_03935	COG0322	excinuclease ABC activity
EG63_03940	COG0460	homoserine dehydrogenase
EG63_03950	COG3118	belongs to the thioredoxin family
EG63_03955	COG0492	ferredoxin-NADP+ reductase activity
EG63_03970	COG0724	RNA recognition motif
EG63_03985	COG0517	IMP dehydrogenase activity
EG63_03985	COG0516	GMP reductase activity
EG63_03990	COG0154	amidase activity
EG63_03995	COG0237	dephospho-CoA kinase activity
EG63_04000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EG63_04015	COG0776	regulation of translation
EG63_04050	COG1086	Polysaccharide biosynthesis protein
EG63_04055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EG63_04070	COG0351	phosphomethylpyrimidine kinase
EG63_04100	COG0671	phosphoesterase, PA-phosphatase related
EG63_04120	COG0488	(ABC) transporter
EG63_04135	COG1696	Membrane protein involved in D-alanine export
EG63_04155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG63_04160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EG63_04170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EG63_04205	COG0375	protein maturation
EG63_04210	COG1749	Flagellar hook protein flgE
EG63_04215	COG2134	cdp-diacylglycerol pyrophosphatase
EG63_04220	COG2824	Alkylphosphonate utilization operon protein PhnA
EG63_04235	COG0753	catalase activity
EG63_04265	COG0632	four-way junction helicase activity
EG63_04275	COG0728	peptidoglycan biosynthetic process
EG63_04295	COG1120	ATPase activity
EG63_04300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG63_04305	COG0300	oxidoreductase activity
EG63_04310	COG1607	acyl-coa hydrolase
EG63_04355	COG0409	Hydrogenase expression formation protein
EG63_04360	COG0298	carbon dioxide binding
EG63_04365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EG63_04380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EG63_04395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EG63_04400	COG1749	Flagellar hook protein flgE
EG63_04400	COG1749	Flagellar hook protein flgE
EG63_04445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EG63_04450	COG0670	Belongs to the BI1 family
EG63_04455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG63_04470	COG1942	4-Oxalocrotonate Tautomerase
EG63_04485	COG0501	Belongs to the peptidase M48B family
EG63_04495	COG0142	geranyltranstransferase activity
EG63_04510	COG0720	synthase
EG63_04515	COG0602	queuosine metabolic process
EG63_04530	COG0477	Major facilitator Superfamily
EG63_04550	COG0765	amino acid transport
EG63_04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG63_04565	COG1115	amino acid carrier protein
EG63_04570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG63_04575	COG0251	oxidation-reduction process
EG63_04605	COG1757	Na H antiporter
EG63_04630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EG63_04640	COG1546	Belongs to the CinA family
EG63_04640	COG1058	Belongs to the CinA family
EG63_04655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EG63_04660	COG0564	pseudouridine synthase activity
EG63_04665	COG1519	Transferase
EG63_04675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EG63_04685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EG63_04690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG63_04695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EG63_04710	COG3309	Virulence-associated protein D
EG63_04735	COG0751	glycine-tRNA ligase activity
EG63_04745	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EG63_04750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EG63_04755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EG63_04765	COG0849	cell division
EG63_04770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EG63_04790	COG0750	zinc metalloprotease
EG63_04810	COG0668	transmembrane transport
EG63_04930	COG1166	arginine decarboxylase activity
EG63_04945	COG0500	methyltransferase
EG63_04955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG63_04955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG63_04960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EG63_04965	COG0668	transmembrane transport
EG63_05025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EG63_05030	COG0537	adenosine 5'-monophosphoramidase activity
EG63_05040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG63_05040	COG0072	phenylalanine-tRNA ligase activity
EG63_05045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EG63_05055	COG0539	negative regulation of cytoplasmic translation
EG63_05055	COG1185	polyribonucleotide nucleotidyltransferase activity
EG63_05065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EG63_05070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EG63_05075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EG63_05085	COG0835	chemotaxis
EG63_05085	COG0784	Response regulator, receiver
EG63_05090	COG0643	Histidine kinase
EG63_05090	COG2198	Histidine kinase
EG63_05100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EG63_05105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EG63_05115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EG63_05140	COG0501	Belongs to the peptidase M48B family
EG63_05145	COG2890	protein-(glutamine-N5) methyltransferase activity
EG63_05150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG63_05160	COG1333	cytochrome c biogenesis protein
EG63_05160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EG63_05180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EG63_05195	COG0511	ligase activity, forming carbon-carbon bonds
EG63_05200	COG0439	Biotin carboxylase
EG63_05220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EG63_05230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EG63_05270	COG4221	oxidoreductase activity
EG63_05275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EG63_05280	COG0800	Aldolase
EG63_05285	COG0129	dihydroxy-acid dehydratase activity
EG63_05290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EG63_05295	COG0363	glucosamine-6-phosphate deaminase activity
EG63_05305	COG1064	alcohol dehydrogenase
EG63_05330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EG63_05340	COG0674	pyruvate-flavodoxin oxidoreductase activity
EG63_05345	COG1013	pyruvate-flavodoxin oxidoreductase activity
EG63_05350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EG63_05360	COG0556	nucleotide-excision repair
EG63_05390	COG0405	Gamma-glutamyltransferase
EG63_05420	COG1047	Peptidyl-prolyl cis-trans
EG63_05430	COG2885	chlorophyll binding
EG63_05435	COG0823	Involved in the tonB-independent uptake of proteins
EG63_05445	COG0848	biopolymer transport protein
EG63_05450	COG0811	peptide transport
EG63_05455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EG63_05490	COG1475	DNA binding
EG63_05495	COG1192	Involved in chromosome partitioning
EG63_05505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EG63_05540	COG0335	large ribosomal subunit rRNA binding
EG63_05545	COG0336	Belongs to the RNA methyltransferase TrmD family
EG63_05550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EG63_05560	COG0228	four-way junction DNA binding
EG63_05565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EG63_05570	COG0525	valine-tRNA ligase activity
EG63_05575	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EG63_05580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EG63_05600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EG63_05605	COG2184	nucleotidyltransferase activity
EG63_05615	COG0716	FMN binding
EG63_05630	COG0492	ferredoxin-NADP+ reductase activity
EG63_05650	COG1966	Carbon starvation protein
EG63_05660	COG0765	amino acid transport
EG63_05665	COG1126	abc transporter atp-binding protein
EG63_05680	COG0738	Major facilitator superfamily
EG63_05685	COG2252	PERMEase
EG63_05720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EG63_05725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EG63_05735	COG2814	Major facilitator Superfamily
EG63_05740	COG0037	tRNA processing
EG63_05745	COG0569	domain protein
EG63_05745	COG0475	glutathione-regulated potassium exporter activity
EG63_05770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EG63_05790	COG0667	Aldo Keto reductase
EG63_05805	COG0049	tRNA binding
EG63_05815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EG63_05815	COG0085	RNA polymerase activity
EG63_05845	COG0250	Participates in transcription elongation, termination and antitermination
EG63_05865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EG63_05890	COG1132	(ABC) transporter
EG63_05915	COG1045	serine acetyltransferase
EG63_05945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EG63_05955	COG0151	Belongs to the GarS family
EG63_05980	COG1131	(ABC) transporter
EG63_05985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EG63_06005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EG63_06010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG63_06015	COG2863	cytochrome
EG63_06025	COG0527	aspartate kinase activity
EG63_06040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EG63_06050	COG0697	spore germination
EG63_06065	COG0505	Belongs to the CarA family
EG63_06090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EG63_06120	COG0629	single-stranded DNA binding
EG63_06130	COG1466	dna polymerase III delta subunit
EG63_06135	COG0557	exoribonuclease II activity
EG63_06150	COG4174	ABC transporter (Permease)
EG63_06155	COG4166	transmembrane transport
EG63_06160	COG0180	Tryptophanyl-tRNA synthetase
EG63_06170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EG63_06190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EG63_06195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG63_06230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EG63_06235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG63_06240	COG0839	Belongs to the complex I subunit 6 family
EG63_06250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EG63_06255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG63_06260	COG1007	ATP synthesis coupled electron transport
EG63_06295	COG0133	tryptophan synthase activity
EG63_06300	COG0134	indole-3-glycerol-phosphate synthase activity
EG63_06300	COG0135	phosphoribosylanthranilate isomerase activity
EG63_06305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EG63_06310	COG0512	Glutamine amidotransferase of anthranilate synthase
EG63_06315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG63_06320	COG0859	PFAM glycosyl transferase family 9
EG63_06335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EG63_06370	COG0202	RNA polymerase activity
EG63_06375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EG63_06400	COG0024	Methionine aminopeptidase
EG63_06405	COG0201	protein transport
EG63_06420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EG63_06450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EG63_06470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EG63_06475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EG63_06495	COG0088	Forms part of the polypeptide exit tunnel
EG63_06500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EG63_06505	COG0051	transcription antitermination factor activity, RNA binding
EG63_06530	COG0114	fumarate hydratase activity
EG63_06545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG63_06550	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EG63_06555	COG1687	branched-chain amino acid
EG63_06560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EG63_06565	COG0484	heat shock protein binding
EG63_06575	COG0482	sulfurtransferase activity
EG63_06585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EG63_06595	COG0811	peptide transport
EG63_06600	COG0848	biopolymer transport protein
EG63_06605	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EG63_06620	COG0861	Integral membrane protein TerC family
EG63_06625	COG0598	Magnesium transport protein CorA
EG63_06630	COG0126	phosphoglycerate kinase activity
EG63_06635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG63_06645	COG0204	Acyl-transferase
EG63_06655	COG0793	Belongs to the peptidase S41A family
EG63_06690	COG0157	Belongs to the NadC ModD family
EG63_06695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EG63_06715	COG0109	protoheme IX farnesyltransferase activity
EG63_06725	COG0305	Participates in initiation and elongation during chromosome replication
EG63_06730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EG63_06730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EG63_06740	COG0745	RESPONSE REGULATOR receiver
EG63_06755	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EG63_06765	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EG63_06780	COG1077	Cell shape determining protein MreB Mrl
EG63_06785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EG63_06790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG63_06795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EG63_06810	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EG63_06815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EG63_06820	COG0287	Prephenate dehydrogenase
EG63_06830	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EG63_06850	COG1295	ribonuclease BN
EG63_06900	COG0799	negative regulation of ribosome biogenesis
EG63_06925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EG63_06930	COG1987	bacterial-type flagellum assembly
EG63_06935	COG1157	protein secretion by the type III secretion system
EG63_06940	COG4962	Type ii secretion system protein e
EG63_06950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EG63_06980	COG0517	IMP dehydrogenase activity
EG63_06980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EG63_07005	COG0732	type I restriction modification DNA specificity domain
EG63_07010	COG0788	formyltetrahydrofolate deformylase activity
EG63_07015	COG0616	signal peptide processing
EG63_07060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EG63_07070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EG63_07080	COG0811	peptide transport
EG63_07085	COG0848	biopolymer transport protein
EG63_07095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EG63_07100	COG0706	membrane insertase activity
EG63_07110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EG63_07160	COG3118	belongs to the thioredoxin family
EG63_07165	COG1187	pseudouridine synthase activity
EG63_07170	COG0587	DNA-directed DNA polymerase activity
EG63_07200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EG63_07205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EG63_07215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG63_07225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG63_07225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG63_07250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EG63_07255	COG0163	prenyltransferase activity
EG63_07265	COG0210	DNA helicase
EG63_07275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EG63_07290	COG2226	methyltransferase
EG63_07300	COG1739	Uncharacterized protein family UPF0029
EG63_07315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG63_07325	COG1253	flavin adenine dinucleotide binding
EG63_07330	COG0306	phosphate transporter
EG63_07335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EG63_07345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EG63_07350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EG63_07395	COG2217	Heavy metal translocating P-type atpase
EG63_07410	COG0786	glutamate:sodium symporter activity
EG63_07420	COG0348	domain, Protein
EG63_07425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EG63_07455	COG0195	Participates in both transcription termination and antitermination
EG63_07515	COG3451	type IV secretory pathway VirB4
EG63_07555	COG4962	Type ii secretion system protein e
EG63_07580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG63_07605	COG1192	Involved in chromosome partitioning
EG63_07675	COG3550	peptidyl-serine autophosphorylation
EG63_07685	COG3550	peptidyl-serine autophosphorylation
EG63_07690	COG4974	Belongs to the 'phage' integrase family
EG63_07730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EG63_07745	COG0708	Exodeoxyribonuclease III
EG63_07760	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EG63_07775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EG63_07780	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EG63_07815	COG4772	TonB-dependent receptor
EG63_07825	COG0010	Belongs to the arginase family
EG63_07830	COG0686	Belongs to the AlaDH PNT family
EG63_07850	COG0497	DNA recombination
EG63_07865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EG63_07875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EG63_07910	COG0723	plastoquinol--plastocyanin reductase activity
EG63_07915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EG63_07925	COG0739	heme binding
EG63_07935	COG0285	dihydrofolate synthase activity
EG63_07955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG63_07960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG63_07965	COG1862	Preprotein translocase
EG63_07970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EG63_07975	COG1074	ATP-dependent DNA helicase activity
EG63_07995	COG0768	penicillin binding
EG63_08005	COG1558	bacterial-type flagellum-dependent cell motility
EG63_08010	COG1815	bacterial-type flagellum-dependent cell motility
EG63_08020	COG0772	Belongs to the SEDS family
EG63_08030	COG0450	alkyl hydroperoxide reductase
EG63_08050	COG0768	penicillin binding
EG63_08075	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EG63_08080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EG63_08085	COG0741	lytic transglycosylase activity
EG63_08085	COG1388	LysM domain
EG63_08090	COG0084	hydrolase, TatD family'
EG63_08095	COG0307	riboflavin synthase, alpha
EG63_08110	COG2011	ABC-type metal ion transport system permease component
EG63_08120	COG0671	phosphoesterase, PA-phosphatase related
EG63_08125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EG63_08130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EG63_08145	COG4786	Flagellar basal body rod
EG63_08165	COG4735	regulation of single-species biofilm formation
EG63_08170	COG4735	regulation of single-species biofilm formation
