locus-tag	class	description
HPOKI128_00010	COG4735	regulation of single-species biofilm formation
HPOKI128_00025	COG4786	Flagellar basal body rod
HPOKI128_00045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPOKI128_00050	COG0671	phosphoesterase, PA-phosphatase related
HPOKI128_00060	COG2011	ABC-type metal ion transport system permease component
HPOKI128_00075	COG0307	riboflavin synthase, alpha
HPOKI128_00080	COG0084	hydrolase, TatD family'
HPOKI128_00085	COG1388	LysM domain
HPOKI128_00085	COG0741	lytic transglycosylase activity
HPOKI128_00090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPOKI128_00095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HPOKI128_00120	COG0768	penicillin binding
HPOKI128_00130	COG0450	alkyl hydroperoxide reductase
HPOKI128_00140	COG0772	Belongs to the SEDS family
HPOKI128_00145	COG1815	bacterial-type flagellum-dependent cell motility
HPOKI128_00150	COG1558	bacterial-type flagellum-dependent cell motility
HPOKI128_00160	COG0768	penicillin binding
HPOKI128_00170	COG1106	Psort location Cytoplasmic, score
HPOKI128_00195	COG0723	plastoquinol--plastocyanin reductase activity
HPOKI128_00200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPOKI128_00210	COG0739	heme binding
HPOKI128_00220	COG0285	dihydrofolate synthase activity
HPOKI128_00230	COG0495	leucyl-tRNA aminoacylation
HPOKI128_00240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPOKI128_00245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPOKI128_00250	COG1862	Preprotein translocase
HPOKI128_00260	COG1074	ATP-dependent DNA helicase activity
HPOKI128_00300	COG1943	Transposase
HPOKI128_00305	COG0270	DNA (cytosine-5-)-methyltransferase activity
HPOKI128_00320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPOKI128_00325	COG0506	proline dehydrogenase activity
HPOKI128_00325	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HPOKI128_00325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HPOKI128_00390	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPOKI128_00395	COG0830	nickel cation binding
HPOKI128_00420	COG0832	Belongs to the urease beta subunit family
HPOKI128_00420	COG0831	urea catabolic process
HPOKI128_00430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPOKI128_00445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPOKI128_00465	COG1943	Transposase
HPOKI128_00480	COG0840	transmembrane signaling receptor activity
HPOKI128_00520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPOKI128_00525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPOKI128_00530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HPOKI128_00560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPOKI128_00570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HPOKI128_00580	COG0840	transmembrane signaling receptor activity
HPOKI128_00585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPOKI128_00595	COG1216	Glycosyl transferase, family 2
HPOKI128_00605	COG0737	Belongs to the 5'-nucleotidase family
HPOKI128_00615	COG0626	cystathionine gamma-synthase activity
HPOKI128_00620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HPOKI128_00640	COG1420	regulation of RNA biosynthetic process
HPOKI128_00660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HPOKI128_00665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPOKI128_00665	COG0551	DNA topoisomerase type I activity
HPOKI128_00670	COG0731	radical SAM domain protein
HPOKI128_00680	COG0574	Belongs to the PEP-utilizing enzyme family
HPOKI128_00680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPOKI128_00695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPOKI128_00740	COG1760	l-serine dehydratase
HPOKI128_00745	COG0814	amino acid
HPOKI128_00750	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HPOKI128_00765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPOKI128_00775	COG1139	Iron-sulfur cluster binding protein
HPOKI128_00780	COG0247	lactate metabolic process
HPOKI128_00785	COG1620	l-lactate permease
HPOKI128_00790	COG1620	l-lactate permease
HPOKI128_00795	COG1194	a g-specific adenine glycosylase
HPOKI128_00800	COG0471	metal ion transport
HPOKI128_00805	COG3278	Belongs to the heme-copper respiratory oxidase family
HPOKI128_00890	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPOKI128_00900	COG0217	transcriptional regulatory protein
HPOKI128_00905	COG0113	porphobilinogen synthase activity
HPOKI128_00910	COG2205	protein histidine kinase activity
HPOKI128_00945	COG0303	'Molybdopterin
HPOKI128_00960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HPOKI128_00965	COG0191	fructose-bisphosphate aldolase activity
HPOKI128_00980	COG2089	acid synthase
HPOKI128_00985	COG1136	(ABC) transporter
HPOKI128_00990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HPOKI128_01045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPOKI128_01050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HPOKI128_01055	COG1053	succinate dehydrogenase
HPOKI128_01070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HPOKI128_01075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPOKI128_01095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HPOKI128_01130	COG0489	protein tyrosine kinase activity
HPOKI128_01145	COG0326	Molecular chaperone. Has ATPase activity
HPOKI128_01150	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPOKI128_01170	COG0471	metal ion transport
HPOKI128_01175	COG0575	Belongs to the CDS family
HPOKI128_01190	COG1881	PFAM PEBP family protein
HPOKI128_01200	COG1104	cysteine desulfurase activity
HPOKI128_01220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPOKI128_01230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPOKI128_01230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPOKI128_01240	COG0730	response to heat
HPOKI128_01250	COG0659	secondary active sulfate transmembrane transporter activity
HPOKI128_01280	COG0754	glutathionylspermidine amidase activity
HPOKI128_01295	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPOKI128_01335	COG0783	Belongs to the Dps family
HPOKI128_01345	COG3951	Flagellar rod assembly protein muramidase FlgJ
HPOKI128_01370	COG4172	Belongs to the ABC transporter superfamily
HPOKI128_01375	COG4239	(ABC) transporter, permease
HPOKI128_01415	COG0750	zinc metalloprotease
HPOKI128_01450	COG0785	Cytochrome C biogenesis protein
HPOKI128_01455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HPOKI128_01460	COG0402	S-adenosylhomocysteine deaminase activity
HPOKI128_01495	COG0727	PFAM Uncharacterised protein family (UPF0153)
HPOKI128_01505	COG0134	indole-3-glycerol-phosphate synthase activity
HPOKI128_01515	COG0248	Ppx GppA phosphatase
HPOKI128_01520	COG0859	PFAM glycosyl transferase family 9
HPOKI128_01550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPOKI128_01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPOKI128_01575	COG0019	diaminopimelate decarboxylase activity
HPOKI128_01590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPOKI128_01595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPOKI128_01615	COG0747	negative chemotaxis
HPOKI128_01620	COG0601	transmembrane transport
HPOKI128_01625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPOKI128_01630	COG0444	Belongs to the ABC transporter superfamily
HPOKI128_01635	COG4608	Belongs to the ABC transporter superfamily
HPOKI128_01670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPOKI128_01675	COG0726	polysaccharide deacetylase
HPOKI128_01685	COG0523	cobalamin synthesis protein
HPOKI128_01695	COG0748	coenzyme F420 binding
HPOKI128_01735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HPOKI128_01740	COG3980	spore coat polysaccharide biosynthesis protein
HPOKI128_01745	COG3980	spore coat polysaccharide biosynthesis protein
HPOKI128_01750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPOKI128_01755	COG1663	tetraacyldisaccharide 4'-kinase activity
HPOKI128_01775	COG2894	cell division
HPOKI128_01780	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HPOKI128_01785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPOKI128_01785	COG0758	DNA mediated transformation
HPOKI128_01795	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPOKI128_01815	COG0564	pseudouridine synthase activity
HPOKI128_01825	COG0504	CTP synthase activity
HPOKI128_01835	COG1766	The M ring may be actively involved in energy transduction
HPOKI128_01840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HPOKI128_01850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPOKI128_01870	COG4786	Flagellar basal body rod
HPOKI128_01875	COG0477	Major facilitator Superfamily
HPOKI128_01880	COG1674	ftsk spoiiie
HPOKI128_01900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPOKI128_01920	COG1132	(ABC) transporter
HPOKI128_01945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HPOKI128_01965	COG2608	mercury ion transmembrane transporter activity
HPOKI128_01970	COG2217	Heavy metal translocating P-type atpase
HPOKI128_01975	COG1183	phosphatidylcholine synthase activity
HPOKI128_01985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPOKI128_02020	COG0357	Ribosomal RNA small subunit methyltransferase G
HPOKI128_02030	COG0805	protein transport
HPOKI128_02075	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HPOKI128_02085	COG0083	homoserine kinase activity
HPOKI128_02115	COG1408	metallophosphoesterase
HPOKI128_02120	COG0745	RESPONSE REGULATOR receiver
HPOKI128_02125	COG2404	hydrolase activity, acting on ester bonds
HPOKI128_02130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HPOKI128_02150	COG0006	proline dipeptidase activity
HPOKI128_02155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPOKI128_02160	COG1419	protein localization to endoplasmic reticulum
HPOKI128_02165	COG0455	bacterial-type flagellum organization
HPOKI128_02175	COG1191	sigma factor activity
HPOKI128_02180	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HPOKI128_02185	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HPOKI128_02185	COG1776	CheC inhibitor of MCP methylation
HPOKI128_02200	COG0735	belongs to the Fur family
HPOKI128_02205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HPOKI128_02205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HPOKI128_02210	COG0789	Transcriptional regulator
HPOKI128_02215	COG0484	heat shock protein binding
HPOKI128_02230	COG0745	RESPONSE REGULATOR receiver
HPOKI128_02235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HPOKI128_02235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HPOKI128_02245	COG0833	amino acid
HPOKI128_02250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPOKI128_02260	COG1028	Short-chain dehydrogenase reductase Sdr
HPOKI128_02280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPOKI128_02480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPOKI128_02490	COG0824	Thioesterase
HPOKI128_02495	COG0733	neurotransmitter:sodium symporter activity
HPOKI128_02500	COG0733	neurotransmitter:sodium symporter activity
HPOKI128_02510	COG0592	DNA-directed DNA polymerase activity
HPOKI128_02515	COG0187	DNA topoisomerase II activity
HPOKI128_02530	COG0741	lytic transglycosylase activity
HPOKI128_02530	COG0739	heme binding
HPOKI128_02530	COG1196	nuclear chromosome segregation
HPOKI128_02545	COG0277	FAD linked oxidase domain protein
HPOKI128_02560	COG0174	glutamine synthetase
HPOKI128_02565	COG3586	endonuclease activity
HPOKI128_02605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPOKI128_02610	COG0254	rRNA binding
HPOKI128_02615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPOKI128_02645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HPOKI128_02660	COG1028	Short-chain dehydrogenase reductase Sdr
HPOKI128_02690	COG0628	permease
HPOKI128_02700	COG0012	GTP binding
HPOKI128_02725	COG0698	ribose 5-phosphate isomerase
HPOKI128_02730	COG1994	Peptidase M50
HPOKI128_02735	COG0681	Belongs to the peptidase S26 family
HPOKI128_02775	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HPOKI128_02775	COG1776	CheC inhibitor of MCP methylation
HPOKI128_02780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPOKI128_02785	COG1918	ferrous iron import across plasma membrane
HPOKI128_02805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPOKI128_02805	COG0674	pyruvate-flavodoxin oxidoreductase activity
HPOKI128_02810	COG1013	pyruvate-flavodoxin oxidoreductase activity
HPOKI128_02850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HPOKI128_02855	COG0156	8-amino-7-oxononanoate synthase activity
HPOKI128_02860	COG0840	transmembrane signaling receptor activity
HPOKI128_02870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HPOKI128_02910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPOKI128_02920	COG1136	(ABC) transporter
HPOKI128_02940	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPOKI128_02950	COG3306	glycosyltransferase involved in LPS biosynthesis
HPOKI128_02960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HPOKI128_02965	COG1193	negative regulation of DNA recombination
HPOKI128_02980	COG0436	Aminotransferase
HPOKI128_02990	COG2171	N-acyltransferase activity
HPOKI128_03005	COG2249	NAD(P)H dehydrogenase (quinone) activity
HPOKI128_03010	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HPOKI128_03015	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HPOKI128_03020	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HPOKI128_03025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HPOKI128_03030	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HPOKI128_03055	COG0617	tRNA 3'-terminal CCA addition
HPOKI128_03060	COG0778	Nitroreductase
HPOKI128_03070	COG0762	integral membrane protein
HPOKI128_03095	COG1027	Aspartate ammonia-lyase
HPOKI128_03110	COG0560	Phosphoserine phosphatase
HPOKI128_03115	COG1528	Iron-storage protein
HPOKI128_03120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HPOKI128_03125	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPOKI128_03130	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HPOKI128_03140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPOKI128_03155	COG0328	RNA-DNA hybrid ribonuclease activity
HPOKI128_03165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPOKI128_03175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HPOKI128_03205	COG4974	Belongs to the 'phage' integrase family
HPOKI128_03210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPOKI128_03215	COG0730	response to heat
HPOKI128_03225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPOKI128_03250	COG1338	Plays a role in the flagellum-specific transport system
HPOKI128_03260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HPOKI128_03285	COG0183	Belongs to the thiolase family
HPOKI128_03290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HPOKI128_03295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HPOKI128_03300	COG2031	fatty acid transporter
HPOKI128_03310	COG0145	ligase activity
HPOKI128_03315	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
HPOKI128_03320	COG4647	ligase activity
HPOKI128_03330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HPOKI128_03335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPOKI128_03345	COG2204	response regulator
HPOKI128_03350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPOKI128_03370	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HPOKI128_03395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HPOKI128_03410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPOKI128_03415	COG1279	arginine transmembrane transporter activity
HPOKI128_03435	COG0252	asparaginase activity
HPOKI128_03440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HPOKI128_03455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPOKI128_03460	COG0037	tRNA processing
HPOKI128_03490	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HPOKI128_03495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HPOKI128_03500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HPOKI128_03515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HPOKI128_03525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPOKI128_03545	COG0564	pseudouridine synthase activity
HPOKI128_03555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HPOKI128_03580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HPOKI128_03615	COG2056	Na+-H+ antiporter family
HPOKI128_03620	COG0534	Mate efflux family protein
HPOKI128_03640	COG0552	protein localization to endoplasmic reticulum
HPOKI128_03665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPOKI128_03675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HPOKI128_03685	COG0860	N-Acetylmuramoyl-L-alanine amidase
HPOKI128_03690	COG0126	phosphoglycerate kinase activity
HPOKI128_03695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPOKI128_03700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPOKI128_03705	COG1758	RNA polymerase activity
HPOKI128_03720	COG1049	propionate catabolic process, 2-methylcitrate cycle
HPOKI128_03780	COG2217	Heavy metal translocating P-type atpase
HPOKI128_03785	COG0606	chelatase, subunit chli
HPOKI128_03795	COG0740	serine-type endopeptidase activity
HPOKI128_03820	COG0521	Mo-molybdopterin cofactor biosynthetic process
HPOKI128_03825	COG0314	molybdopterin synthase activity
HPOKI128_03845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPOKI128_03845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPOKI128_03865	COG0736	holo-[acyl-carrier-protein] synthase activity
HPOKI128_03870	COG1580	Controls the rotational direction of flagella during chemotaxis
HPOKI128_03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HPOKI128_03895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HPOKI128_03900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HPOKI128_03905	COG1360	Flagellar Motor Protein
HPOKI128_03925	COG1732	Glycine betaine
HPOKI128_03930	COG1125	glycine betaine transport
HPOKI128_03930	COG0517	IMP dehydrogenase activity
HPOKI128_03950	COG0460	homoserine dehydrogenase
HPOKI128_03960	COG3118	belongs to the thioredoxin family
HPOKI128_03965	COG0492	ferredoxin-NADP+ reductase activity
HPOKI128_03975	COG0724	RNA recognition motif
HPOKI128_03990	COG0517	IMP dehydrogenase activity
HPOKI128_03990	COG0516	GMP reductase activity
HPOKI128_04000	COG0237	dephospho-CoA kinase activity
HPOKI128_04020	COG0776	regulation of translation
HPOKI128_04045	COG1086	Polysaccharide biosynthesis protein
HPOKI128_04050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPOKI128_04065	COG0351	phosphomethylpyrimidine kinase
HPOKI128_04090	COG0671	phosphoesterase, PA-phosphatase related
HPOKI128_04100	COG0488	(ABC) transporter
HPOKI128_04120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPOKI128_04125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HPOKI128_04135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPOKI128_04150	COG0756	dUTP diphosphatase activity
HPOKI128_04155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HPOKI128_04170	COG0375	protein maturation
HPOKI128_04175	COG1749	Flagellar hook protein flgE
HPOKI128_04180	COG2134	cdp-diacylglycerol pyrophosphatase
HPOKI128_04200	COG0753	catalase activity
HPOKI128_04235	COG0728	peptidoglycan biosynthetic process
HPOKI128_04250	COG1120	ATPase activity
HPOKI128_04255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPOKI128_04260	COG0300	oxidoreductase activity
HPOKI128_04265	COG1607	acyl-coa hydrolase
HPOKI128_04270	COG3041	Addiction module toxin RelE StbE family
HPOKI128_04310	COG0409	Hydrogenase expression formation protein
HPOKI128_04315	COG0298	carbon dioxide binding
HPOKI128_04320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPOKI128_04340	COG0280	phosphate acetyltransferase
HPOKI128_04350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HPOKI128_04355	COG1749	Flagellar hook protein flgE
HPOKI128_04355	COG1749	Flagellar hook protein flgE
HPOKI128_04400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HPOKI128_04405	COG0670	Belongs to the BI1 family
HPOKI128_04410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HPOKI128_04425	COG1942	4-Oxalocrotonate Tautomerase
HPOKI128_04450	COG0142	geranyltranstransferase activity
HPOKI128_04465	COG0720	synthase
HPOKI128_04470	COG0602	queuosine metabolic process
HPOKI128_04485	COG0477	Major facilitator Superfamily
HPOKI128_04495	COG0765	amino acid transport
HPOKI128_04500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPOKI128_04510	COG1115	amino acid carrier protein
HPOKI128_04515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HPOKI128_04520	COG0251	oxidation-reduction process
HPOKI128_04545	COG1757	Na H antiporter
HPOKI128_04570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPOKI128_04580	COG1058	Belongs to the CinA family
HPOKI128_04580	COG1546	Belongs to the CinA family
HPOKI128_04600	COG0564	pseudouridine synthase activity
HPOKI128_04605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HPOKI128_04605	COG1519	Transferase
HPOKI128_04615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPOKI128_04630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HPOKI128_04675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPOKI128_04680	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPOKI128_04685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HPOKI128_04695	COG0849	cell division
HPOKI128_04700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPOKI128_04730	COG0750	zinc metalloprotease
HPOKI128_04825	COG1166	arginine decarboxylase activity
HPOKI128_04850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPOKI128_04850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPOKI128_04855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HPOKI128_04860	COG0668	transmembrane transport
HPOKI128_04925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPOKI128_04930	COG0537	adenosine 5'-monophosphoramidase activity
HPOKI128_04945	COG0072	phenylalanine-tRNA ligase activity
HPOKI128_04945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPOKI128_04960	COG1185	polyribonucleotide nucleotidyltransferase activity
HPOKI128_04960	COG0539	negative regulation of cytoplasmic translation
HPOKI128_04970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HPOKI128_04975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HPOKI128_04980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPOKI128_04990	COG0835	chemotaxis
HPOKI128_04990	COG0784	Response regulator, receiver
HPOKI128_04995	COG2198	Histidine kinase
HPOKI128_04995	COG0643	Histidine kinase
HPOKI128_05005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPOKI128_05010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HPOKI128_05020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPOKI128_05050	COG2890	protein-(glutamine-N5) methyltransferase activity
HPOKI128_05055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HPOKI128_05065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPOKI128_05065	COG1333	cytochrome c biogenesis protein
HPOKI128_05085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HPOKI128_05100	COG0511	ligase activity, forming carbon-carbon bonds
HPOKI128_05105	COG0439	Biotin carboxylase
HPOKI128_05125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HPOKI128_05135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPOKI128_05140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HPOKI128_05175	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPOKI128_05180	COG0800	Aldolase
HPOKI128_05185	COG0129	dihydroxy-acid dehydratase activity
HPOKI128_05190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPOKI128_05195	COG0363	glucosamine-6-phosphate deaminase activity
HPOKI128_05205	COG1064	alcohol dehydrogenase
HPOKI128_05235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPOKI128_05245	COG0674	pyruvate-flavodoxin oxidoreductase activity
HPOKI128_05250	COG1013	pyruvate-flavodoxin oxidoreductase activity
HPOKI128_05255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPOKI128_05285	COG0405	Gamma-glutamyltransferase
HPOKI128_05315	COG1047	Peptidyl-prolyl cis-trans
HPOKI128_05325	COG2885	chlorophyll binding
HPOKI128_05330	COG0823	Involved in the tonB-independent uptake of proteins
HPOKI128_05340	COG0848	biopolymer transport protein
HPOKI128_05345	COG0811	peptide transport
HPOKI128_05355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPOKI128_05385	COG1475	DNA binding
HPOKI128_05390	COG1192	Involved in chromosome partitioning
HPOKI128_05395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HPOKI128_05395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HPOKI128_05400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPOKI128_05445	COG0336	Belongs to the RNA methyltransferase TrmD family
HPOKI128_05465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPOKI128_05470	COG0525	valine-tRNA ligase activity
HPOKI128_05475	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HPOKI128_05495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPOKI128_05500	COG2184	nucleotidyltransferase activity
HPOKI128_05510	COG0716	FMN binding
HPOKI128_05560	COG1966	Carbon starvation protein
HPOKI128_05570	COG0765	amino acid transport
HPOKI128_05575	COG1126	abc transporter atp-binding protein
HPOKI128_05595	COG2252	PERMEase
HPOKI128_05635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HPOKI128_05645	COG2814	Major facilitator Superfamily
HPOKI128_05650	COG0037	tRNA processing
HPOKI128_05655	COG0475	glutathione-regulated potassium exporter activity
HPOKI128_05655	COG0569	domain protein
HPOKI128_05665	COG2814	Major facilitator Superfamily
HPOKI128_05685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPOKI128_05695	COG0859	PFAM glycosyl transferase family 9
HPOKI128_05755	COG0250	Participates in transcription elongation, termination and antitermination
HPOKI128_05800	COG1132	(ABC) transporter
HPOKI128_05815	COG1045	serine acetyltransferase
HPOKI128_05830	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPOKI128_05845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HPOKI128_05855	COG0151	Belongs to the GarS family
HPOKI128_05860	COG1131	(ABC) transporter
HPOKI128_05865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPOKI128_05890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HPOKI128_05895	COG2863	cytochrome
HPOKI128_05905	COG0527	aspartate kinase activity
HPOKI128_05920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPOKI128_05930	COG0697	spore germination
HPOKI128_05950	COG0505	Belongs to the CarA family
HPOKI128_05955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPOKI128_05960	COG0737	Belongs to the 5'-nucleotidase family
HPOKI128_05970	COG0424	maF-like protein
HPOKI128_06010	COG0358	DNA primase activity
HPOKI128_06015	COG0482	sulfurtransferase activity
HPOKI128_06045	COG0784	Response regulator, receiver
HPOKI128_06055	COG0671	phosphoesterase, PA-phosphatase related
HPOKI128_06060	COG2194	sulfuric ester hydrolase activity
HPOKI128_06085	COG0372	Belongs to the citrate synthase family
HPOKI128_06090	COG0538	isocitrate dehydrogenase activity
HPOKI128_06110	COG0589	response to stress
HPOKI128_06115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HPOKI128_06120	COG0542	response to heat
HPOKI128_06170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPOKI128_06190	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HPOKI128_06195	COG2957	Belongs to the agmatine deiminase family
HPOKI128_06225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HPOKI128_06230	COG2176	DNA-directed DNA polymerase activity
HPOKI128_06250	COG0497	DNA recombination
HPOKI128_06275	COG0686	Belongs to the AlaDH PNT family
HPOKI128_06280	COG0010	Belongs to the arginase family
HPOKI128_06290	COG4772	TonB-dependent receptor
HPOKI128_06300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HPOKI128_06310	COG0732	type I restriction modification DNA specificity domain
HPOKI128_06320	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HPOKI128_06325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HPOKI128_06355	COG0708	Exodeoxyribonuclease III
HPOKI128_06370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPOKI128_06415	COG0195	Participates in both transcription termination and antitermination
HPOKI128_06420	COG1921	L-seryl-tRNASec selenium transferase activity
HPOKI128_06440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HPOKI128_06445	COG0348	domain, Protein
HPOKI128_06455	COG0786	glutamate:sodium symporter activity
HPOKI128_06465	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HPOKI128_06525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPOKI128_06535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HPOKI128_06540	COG0306	phosphate transporter
HPOKI128_06545	COG1253	flavin adenine dinucleotide binding
HPOKI128_06555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPOKI128_06570	COG1739	Uncharacterized protein family UPF0029
HPOKI128_06580	COG2226	methyltransferase
HPOKI128_06605	COG0210	DNA helicase
HPOKI128_06615	COG0163	prenyltransferase activity
HPOKI128_06620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPOKI128_06640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPOKI128_06640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPOKI128_06650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HPOKI128_06660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HPOKI128_06665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPOKI128_06695	COG0587	DNA-directed DNA polymerase activity
HPOKI128_06700	COG1187	pseudouridine synthase activity
HPOKI128_06705	COG3118	belongs to the thioredoxin family
HPOKI128_06740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPOKI128_06750	COG0706	membrane insertase activity
HPOKI128_06765	COG0848	biopolymer transport protein
HPOKI128_06770	COG0811	peptide transport
HPOKI128_06790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPOKI128_06840	COG0616	signal peptide processing
HPOKI128_06845	COG0788	formyltetrahydrofolate deformylase activity
HPOKI128_06870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPOKI128_06875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HPOKI128_06875	COG0517	IMP dehydrogenase activity
HPOKI128_06900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HPOKI128_06910	COG4962	Type ii secretion system protein e
HPOKI128_06915	COG1157	protein secretion by the type III secretion system
HPOKI128_06920	COG1987	bacterial-type flagellum assembly
HPOKI128_06925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HPOKI128_06950	COG0799	negative regulation of ribosome biogenesis
HPOKI128_06990	COG1295	ribonuclease BN
HPOKI128_07005	COG3421	Type III restriction
HPOKI128_07010	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HPOKI128_07020	COG0287	Prephenate dehydrogenase
HPOKI128_07025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HPOKI128_07030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPOKI128_07055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPOKI128_07060	COG1077	Cell shape determining protein MreB Mrl
HPOKI128_07075	COG0745	RESPONSE REGULATOR receiver
HPOKI128_07085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPOKI128_07085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HPOKI128_07090	COG0305	Participates in initiation and elongation during chromosome replication
HPOKI128_07100	COG0109	protoheme IX farnesyltransferase activity
HPOKI128_07120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HPOKI128_07125	COG0157	Belongs to the NadC ModD family
HPOKI128_07145	COG0793	Belongs to the peptidase S41A family
HPOKI128_07155	COG0204	Acyl-transferase
HPOKI128_07165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HPOKI128_07170	COG0126	phosphoglycerate kinase activity
HPOKI128_07175	COG0598	Magnesium transport protein CorA
HPOKI128_07180	COG0861	Integral membrane protein TerC family
HPOKI128_07195	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPOKI128_07200	COG0848	biopolymer transport protein
HPOKI128_07205	COG0811	peptide transport
HPOKI128_07215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPOKI128_07235	COG0484	heat shock protein binding
HPOKI128_07240	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HPOKI128_07245	COG1687	branched-chain amino acid
HPOKI128_07250	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPOKI128_07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPOKI128_07270	COG0114	fumarate hydratase activity
HPOKI128_07300	COG0051	transcription antitermination factor activity, RNA binding
HPOKI128_07305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPOKI128_07330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPOKI128_07345	COG0255	Belongs to the universal ribosomal protein uL29 family
HPOKI128_07355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPOKI128_07365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPOKI128_07380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPOKI128_07400	COG0201	protein transport
HPOKI128_07405	COG0024	Methionine aminopeptidase
HPOKI128_07430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPOKI128_07435	COG0202	RNA polymerase activity
HPOKI128_07460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HPOKI128_07480	COG1943	Transposase
HPOKI128_07500	COG0859	PFAM glycosyl transferase family 9
HPOKI128_07505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPOKI128_07510	COG0512	Glutamine amidotransferase of anthranilate synthase
HPOKI128_07515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPOKI128_07520	COG0135	phosphoribosylanthranilate isomerase activity
HPOKI128_07520	COG0134	indole-3-glycerol-phosphate synthase activity
HPOKI128_07525	COG0133	tryptophan synthase activity
HPOKI128_07550	COG1007	ATP synthesis coupled electron transport
HPOKI128_07560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HPOKI128_07570	COG0839	Belongs to the complex I subunit 6 family
HPOKI128_07605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPOKI128_07615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPOKI128_07620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HPOKI128_07640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HPOKI128_07650	COG0180	Tryptophanyl-tRNA synthetase
HPOKI128_07655	COG4166	transmembrane transport
HPOKI128_07660	COG4174	ABC transporter (Permease)
HPOKI128_07675	COG0557	exoribonuclease II activity
HPOKI128_07680	COG1466	dna polymerase III delta subunit
HPOKI128_07695	COG0629	single-stranded DNA binding
HPOKI128_07750	COG0288	reversible hydration of carbon dioxide