LOCUS AB602441 7261 bp RNA linear VRL 15-APR-2011 DEFINITION Hepatitis E virus genomic RNA, complete genome, isolate: wbJOY_06. ACCESSION AB602441 VERSION AB602441.1 KEYWORDS . SOURCE Hepatitis E virus ORGANISM Hepatitis E virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Hepeviridae; Orthohepevirus; Orthohepevirus A. REFERENCE 1 AUTHORS Takahashi,M., Nishizawa,T., Sato,H., Sato,Y., Jirintai, Nagashima,S. and Okamoto,H. TITLE Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype JOURNAL J. Gen. Virol. 92 (PT 4), 902-908 (2011) PUBMED 21228128 REMARK DOI:10.1099/vir.0.029470-0 REFERENCE 2 (bases 1 to 7261) AUTHORS Okamoto,H. and Takahashi,M. TITLE Direct Submission JOURNAL Submitted (29-NOV-2010) Contact:Hiroaki Okamoto Jichi Medical University School of Medicine, Division of Virology, Department of Infection and Immunity; 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan FEATURES Location/Qualifiers source 1..7261 /organism="Hepatitis E virus" /mol_type="genomic RNA" /isolate="wbJOY_06" /isolation_source="Liver tissue from a wild boar" /host="Sus scrofa leucomystax" /db_xref="taxon:12461" /country="Japan:Okayama" /collection_date="12-Jan-2006" /note="unrecognized genotype" 5'UTR 1..25 CDS 26..5155 /note="ORF1" /codon_start=1 /product="non-structural polyprotein" /protein_id="BAJ61825.1" /translation="MEAHQFIKAPGVTTAIEQAALAAANSALANAVVVRPFLSRMQTE ILINLMQPRQLVFRPEVFWNHPIQRVIHNELEQYCRARAGRCLEVGAHPRSINDNPNV LHRCFLRPTGRDVQRWFTAPTRGPAANCRRSALRGTHPVDRTYCFNGFSGCTFAAETG IALYSLHDMWPSEVAEAMARHGMTRLYAVLHLPPEVLLPPGTYHTTSYLLIHDGNRAV ITYEGDSSAGYNHDVTTLRAWVRTTKVTGDHPLVIERVRAIGCHFVLLLTAVPEPSPM PYVPYPRSTEVYVRSIFGPGGSPSLFPSACSTKSTFHAVPVNIWDRLMLFGATLDDQA FCCSRLMTYLRGISYKVTVGALVANEGWNASEDALTAVITAAYLTICHQRYLRTQAIS KGMKRLEQEHAQRFVTRLYSWLFEKSGRDYIPGRQLQFYAQCRRWLSAGFHLDPRVLV FDEATPCRCRSLLRKAVKKFCCFMRWLGQECTCFLQPIEGRVGDEGYDNEAFEGSDVD PAEEVTFSISGSYIVTGDQLLPFYQALGIPPDLAARASRLAATVEVDDTAGRLACRTT LGNKIFTTVFTDGAALEVSGPENYILSFDSAKQCMAAGPHSLSYTLTSAGLEVQLTTA GLDCKVVFPPGAAPPVAPADVTAFCSALYRFNRSTQRHSIAGGLWYHPEGLLGPFPPF SPGHKWESANPFCGESTLYTRTWSTSGFSSHFSPPDLDLVDAPPAAELTAFPVEIDPR PVTSMSPLDSAPGQAAPCPAAHTPSEGPVAREAHPPDPQPPVRSPAIGFSLPGRRLLH TYPDGSKVYAGSLFDSECTWLVNASSPGHRPGGGLCHAFYQRFPESFDPSQFVMTDGH AAYTLTPRPIIHAVAPDYRAAQNPKRLEAAYRETCARRGTAAYPLLGAGIYQVPVSLS FDAWERNHRPGDELYLTEPAIAWFEANKPASPVLTITEDTARAANLALQLDAATEVGR ACAGCRVKPGVVSYQFTAGVPGSGKSRSIQSGEVDVIVVPTRELRNSWRRRGFAAYTP HTAARVTSGRRVVIDEAPSLPPHLLLLHMQRAASVHLLGDPNQIPAIDFEHTGLVPAI RPELVPTKWWHLTHRCPADVCELIRGAYPKIQTSSRVLRSLFWNEPATGQKLVFTQAA KAAHPGAITVHEAQGATFTVTTIIATADARGLIQSSRAHAIVALTRHTEKCVVLDAPG LLREIGISDAIVNNFYLSGGEIGHNRPSVIPRGTIECNVDTLSAFPPSCQFSAFHQLA EELGHRPAPVAAVVPPCPELEQGLLYMPQELTTTDSVLVFELTDIVHCRMAAPTQRKA VLSTLVGRYGRRTRLYEAVHADVRESLCQFIPRLESVSVTTCELSEFVEAMVAKGQDG SAILELDLCNRDVSRITFFQKDCNKFTTGEPIAHGKVGQGISAWSKTFCALFGPWFRA IEKAVLAALAPNVFYGDAFEESVFSAAIAAASNCEVFENDFSEFDSTQNNFSLGLECA IMEECGMPLWXIRLYHLVRSAWILQAPKESLRGFWKKHSGEPGTLLWNTVWNMAVIAH CYEFRSLRLAAFKGDDSVLLCEGYRQGPNAATLITGCGLKLKVDFRPVGLYAGVVVAP GLGALPDVVRFAGRLSEKNWGPGQERAEQLRLAVCDFLRKLTNVAQVCVDVVSRVYGV SPGLVHNLIGMLQAVADGKAHFTETIKPVLDLTDTIVHRVE" CDS 5186..5524 /note="ORF3" /codon_start=1 /product="hypothetical protein" /protein_id="BAJ61826.1" /translation="MPPCVLGLYCCCSSCFCLCCPRHRPVSRLAAVAGGGAAVPEVVS GVTGLTLSPSPSPIFTQPTPLHPMFPLPPGLEPAHGRQPVHSAPPGATSPSAPPPLHV VDLPQLGLRR" CDS 5194..7176 /note="ORF2" /codon_start=1 /product="capsid protein" /protein_id="BAJ61827.1" /translation="MRPRAVLLLFLMLLPMLPAPPAGQPSGRRRGRRSGGSGGGFWGD RVDSQPFALPYIHPTNPFASDVSTSAGAGARARQAARPLGSAWRDQSQRPSASARRRP TPAGASPLTAVAPAPDTTPVPDVDSRGAILRRQYNLSTSPLTSTVASGTNLVLYAAPL GPLLPLQDGTNTHIMATEASNYAQYRVIRATIRYRPLVPNAVGGYAISISFWPQTTTT PTSVDMNSITSTDVRILVQPGLASELIIPSERLHYRNQGWRSVETSGVAEEEATSGLV MLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYTSTARHRLRRG PDGTAELTTTAATRFMKDLYFTGSNGLGEVGRGIALTLFNLADTLLGGLPTELISSAG GQLFYSRPVVSANGEPTVKLYTSVENAQQDKGIAIPHEIDLGDSRVTIQDYDNQHEQD RPTPSPAPSRPFSVLRVNDVLWLTLTAAEYDQTTYGSTTNPMYVSDTVTFVNVATGAQ GVARALDWSKVTFDGRPLTTVQQYGKSFFVLPLRGKLSFWEAGTVKAGYPYNYNTTAS DQILVENAPGHRVCISTYTTNLGSGPVSISAVGVLAPHAATAALEDTADSPARAHTFD DFCPECRILGLQGCAYQSTAAELQRLKMKVGKSREF" 3'UTR 7177..7261 ORIGIN 1 gcaggccacg tatgtggccg acgccatgga ggcccaccag tttataaagg ctcctggcgt 61 cactactgct attgagcagg ctgctctagc agcggccaat tccgccctgg cgaatgctgt 121 ggtggtacgg ccgttccttt cccgtatgca gactgagatt ctcattaatc taatgcagcc 181 cagacaattg gttttccggc ctgaagtctt ttggaaccac ccaatacagc gggttattca 241 taacgagctt gaacaatact gtcgggctcg tgcgggtcgt tgcctcgaag tcggggccca 301 cccccgttcg atcaatgata accctaatgt cttacaccga tgctttctcc gccccaccgg 361 ccgtgatgtc cagcggtggt ttaccgcccc gacccgcggg ccggcggcca actgccgccg 421 gtcggcgctg cgcggcaccc atcctgtgga ccgtacctac tgctttaatg gattctcggg 481 ctgcactttt gcagccgaga ctggtattgc cctttactca cttcatgata tgtggccatc 541 tgaagtggcg gaggccatgg cgcgccatgg catgaccaga ctgtatgcgg ttttacacct 601 cccccctgaa gtactgctcc cacctggcac ctaccacaca acatcctatc ttctcattca 661 tgatgggaat cgtgctgtga ttacttatga gggtgattct agcgcggggt acaatcatga 721 tgtcaccacc cttcgtgcct gggtgcgcac gaccaaggtc accggcgacc acccgttggt 781 gattgagcga gttcgcgcta taggctgtca ctttgtgcta ctcctcacag ctgtgcctga 841 accgtcgccg atgccgtatg tgccttaccc ccgctctact gaggtctatg tccggtccat 901 ttttggcccc gggggctccc cctcgctctt tccctctgcc tgctctacaa agtctacatt 961 ccatgccgtc cctgtcaata tctgggacag gcttatgctg tttggtgcga cgctggacga 1021 tcaggccttt tgctgctcta ggcttatgac atacctccgt ggcattagtt ataaggtgac 1081 agttggcgcg ctagtcgcaa acgagggctg gaatgcctct gaggatgccc tgaccgcggt 1141 gatcacagcg gcctacctca ccatctgcca ccagaggtac cttcgcaccc aggcaatatc 1201 taaggggatg aaaaggctag agcaggagca cgctcagagg ttcgtcaccc gcctttacag 1261 ttggctgttt gagaaatccg gccgtgatta tatccctggc cgccagctgc agttttatgc 1321 ccagtgccgc cggtggctat ccgccgggtt ccatcttgac cctcgggtgc ttgtgtttga 1381 cgaggcaact ccttgccgct gtcgtagcct gctccgcaag gctgttaaga aattctgctg 1441 ttttatgcgg tggcttgggc aagagtgcac gtgtttcctc caacccatcg agggccgtgt 1501 cggtgacgag ggttacgaca atgaggcttt tgaggggtct gatgtggacc ccgcagaaga 1561 ggtcaccttt agcatttcag gctcatacat tgttactggt gaccagctat tgcctttcta 1621 ccaggcactt gggatcccgc ccgatttggc tgctcgtgct agccggcttg cggccactgt 1681 tgaggttgat gatactgccg gccgccttgc ctgcaggaca actctaggta acaagatttt 1741 taccaccgtt tttactgatg gcgccgcact tgaagtcagc ggccctgaga actacatcct 1801 ctcgtttgat tcagctaagc agtgcatggc ggctgggccg catagtctca gctatacatt 1861 gacctccgcg ggtcttgaag tgcagttgac tactgccggg ctcgactgta aggtcgtctt 1921 tccgccgggt gccgcaccac ccgtcgcacc cgccgatgtg acggccttct gctcggcctt 1981 ataccggttt aaccgctcta ctcagcggca ctccattgcc ggcggactgt ggtaccaccc 2041 tgaggggctg ctgggtccgt tccccccgtt ctcccccggt cataaatggg agtccgccaa 2101 cccgttttgc ggggagagca cactctatac ccgcacttgg tcaacatcag gcttttcgag 2161 ccatttctcc ccccctgact tagatttggt tgatgccccg ccggccgctg agcttactgc 2221 ttttcctgta gaaattgacc cgcgtcccgt cacctcgatg tctccactag actctgcacc 2281 agggcaggcc gccccgtgtc cagccgccca tactccttct gaggggcctg tggcccggga 2341 ggcccacccg cctgaccctc agcccccggt ccgctctccg gccatcggtt tttccttgcc 2401 cggccgccgg ctactgcaca cctacccgga cggctccaag gtctacgcgg gttcaytgtt 2461 tgactctgag tgtacctggc tggtcaatgc gtccagcccc ggccaccgcc ccggtggggg 2521 cctgtgtcat gcattctacc agcggtttcc tgagtccttc gacccttccc agtttgtgat 2581 gactgatggc catgcagctt acacacttac cccccggccc ataatccatg ctgtcgcccc 2641 agactatcgg gctgctcaga accccaagag gcttgaggcg gcctaccgtg aaacgtgtgc 2701 ccgtcgcggg actgccgcct accccctgtt gggcgccggg atttatcaag tccctgtgag 2761 tttgagtttt gacgcgtggg agcgtaacca tcgccccggg gatgagttgt acctgactga 2821 acctgcgata gcctggtttg aggctaataa accggcttcg cctgtcctaa ccattactga 2881 ggacacagcg cgtgcggcta atcttgcgct gcaattggac gccgccactg aggtgggccg 2941 tgcgtgtgcc ggctgtcgag tgaagcccgg ggtagtgagt tatcagttta cggccggtgt 3001 ccctgggtct ggcaagtctc gatcgattca gtccggcgaa gtggatgtta tcgttgttcc 3061 aacgcgtgag ctgcgtaact catggcgtcg ccgtgggttc gcagcttaca cgcctcatac 3121 tgcagcccgg gttacttcgg gccgccgggt tgtcatcgac gaggccccgt ccttaccgcc 3181 acacctgctc ctcctccaca tgcagcgtgc tgcatctgtc catcttctgg gggaccctaa 3241 ccaaatccct gccatcgact tcgagcatac cggccttgtg ccagcgatta ggcctgagct 3301 tgtgccgacg aagtggtggc acctaaccca tcggtgccct gcagatgtgt gcgagttgat 3361 tcgtggtgca tacccaaaga tacaaacatc gagccgggtt ctccgctcat tattctggaa 3421 tgagccggct accggccaga aattggtttt cacacaggct gctaaggccg cccaccctgg 3481 tgccataaca gttcatgagg cgcagggtgc caccttcact gtcaccacca tcattgcaac 3541 tgcagatgct cgcggcctta ttcagtcgtc ccgtgcccac gccattgtcg ctctgactcg 3601 tcacaccgag aagtgcgtcg tacttgatgc gccgggcctc ctccgcgaga tcggcatctc 3661 tgacgccatt gtcaataact tttatctctc cgggggtgag attgggcata accgcccgtc 3721 cgtcatcccc cgcggcacca tagaatgtaa cgttgacacg cttagcgctt ttccaccttc 3781 ctgccagttt agcgctttcc atcagttagc cgaggagttg ggccatcggc ctgcccccgt 3841 agccgcagtt gtcccccctt gtcccgagct tgaacaggga ctgctctaca tgccacagga 3901 gttgaccacc accgacagtg tcctggtatt tgagcttacg gacattgtcc actgccgtat 3961 ggccgccccc acccagcgta aggccgtcct atccaccctt gtcggccgtt acgggcggcg 4021 tactaggttg tatgaagctg tccacgctga tgttcgcgag tccttgtgcc agtttatccc 4081 caggttggaa tctgttagcg tcaccacctg tgagttgtct gagtttgtcg aggctatggt 4141 ggcgaaaggc caggacggtt ctgccatcct tgagcttgac ctctgtaacc gagatgtgtc 4201 ccgtattaca ttctttcaga aggactgcaa taagtttacc actggtgagc ccatagcgca 4261 tggcaaagtt ggccagggga tctcggcatg gagcaagacc ttctgcgccc tctttggccc 4321 ctggttccgg gctattgaga aagcggtttt ggccgcgctg gcacccaacg tcttttacgg 4381 ggacgctttc gaagagtcag tcttttctgc ggccattgcc gccgcttcta actgtgaggt 4441 ctttgagaat gacttctccg agtttgacag tacccagaat aacttttccc tcggcytaga 4501 gtgtgctata atggaagagt gtggtatgcc gttgtggatr attcggcttt accatctggt 4561 ccgttccgct tggatcctgc aagcgcccaa ggagtccctg agagggtttt ggaagaagca 4621 ctctggcgag ccggggacct tgttgtggaa tacagtttgg aacatggctg tgattgcgca 4681 ttgttatgag ttccgcagcc taaggttggc ggccttcaag ggagatgact ctgtcttact 4741 ttgcgaaggg taccgccagg gcccaaatgc cgccactttg attaccggct gcgggctcaa 4801 gttgaaggtg gactttcgac cggtaggttt gtacgccggt gtggttgttg cccccggcct 4861 tggtgcgctc cctgacgttg tccggttcgc ggggcgactg tcggagaaaa actggggccc 4921 ggggcaggag cgtgcggagc aactccgcct tgctgtgtgt gattttcttc ggaagcttac 4981 gaatgttgcc caagtttgtg tggatgttgt ttctagggtt tatggagtca gccctggcct 5041 tgtacataac cttattggca tgctgcaggc tgttgctgac ggcaaagcac attttactga 5101 gacaattaaa ccggttttgg acttaacgga cacaattgta catcgggtgg aatgaataac 5161 atgttgtctt gcttggctcg tggatatgcc accatgcgtc ctagggctgt attgctgctg 5221 ttcctcatgc ttctgcctat gctgcccgcg ccaccggccg gtcagccgtc tggccgccgt 5281 cgcgggcggc ggagcggcgg ttccggaggt ggtttctggg gtgaccgggt tgactctcag 5341 cccttcgccc tcccctatat tcacccaacc aacccctttg catccgatgt ttccacttcc 5401 gccggggctg gagcccgcgc acggcaggca gcccgtccac tcggctccgc ctggcgcgac 5461 cagtcccagc gcccctccgc ctctgcacgt cgtagaccta ccccagctgg ggcttcgccg 5521 ttgacggcag tggcccctgc accggacacg actccggtcc ctgatgttga ttcccggggt 5581 gctattttgc gtcggcagta taacctatct acttcccctt taacctctac tgtcgcttca 5641 ggcactaatc tggtgcttta tgcagcccct cttggccccc ttctgccatt gcaagacgga 5701 actaacaccc acattatggc tactgaggct tccaactacg cccagtatcg tgttatccgg 5761 gccactattc gctatcgccc gctggtccca aacgctgtcg gcgggtacgc aatttcaatt 5821 tcattttggc cccagacgac cacgaccccc acttctgttg atatgaactc aatcacatcc 5881 actgatgttc gtatccttgt gcaacctggc ctcgcctctg agcttattat acctagtgag 5941 cgtctccatt atcgtaatca aggttggcgc tcagttgaga cctctggcgt tgctgaggaa 6001 gaggcgactt caggcctcgt tatgttgtgc atccacggtt cgcctgttaa ttcctacacc 6061 aacacacctt ataccggggc tcttggcctg cttgacttcg cacttgagct tgagttccgt 6121 aatttgacac ctgggaacac taacacccgc gtttcccgtt acacaagcac tgctcgccac 6181 cgcctgcggc gggggcctga cggcacggct gagttgacaa ccaccgcagc cacacggttc 6241 atgaaggatt tatacttcac tggttcaaac gggctcggcg aggtcgggcg tggtatagct 6301 ttgaccttgt ttaatcttgc tgacactctt ctcggtgggc tgccgacaga attgatttcg 6361 tcggccgggg gccagttgtt ttactcccgc cccgtcgtct cagccaatgg cgagccgaca 6421 gttaagttgt acacctctgt cgagaatgct cagcaggaca agggtattgc tatccctcat 6481 gagatcgacc tcggtgattc ccgggttact atccaagatt atgacaacca gcacgagcag 6541 gaccgaccaa caccatcacc ggcaccttcg cgcccgttct ctgtcctgcg tgtgaatgac 6601 gtgctttggc tgaccctcac cgctgccgag tatgaccaga ccacctatgg ttcgactacg 6661 aaccccatgt atgtttctga cactgtgaca ttcgtcaatg tagcgactgg tgcacagggt 6721 gttgcccgcg cgcttgactg gtccaaagtc acttttgacg gccgcccgct taccactgtc 6781 caacagtatg gcaagtcttt ctttgtcttg cctctccgcg gtaagctttc gttctgggag 6841 gcgggtaccg tgaaggctgg gtacccttac aattataaca caactgctag tgaccagatc 6901 ttagttgaga atgccccggg ccatcgtgtt tgcatttcga cctatactac taatttgggc 6961 tctgggccag tgtcgatctc ggctgtcggc gtgttggcac ctcatgcggc tactgctgcg 7021 ttggaggaca ccgctgactc cccagcccgc gcccacactt ttgatgattt ttgccctgag 7081 tgccgcattc tggggcttca gggctgtgct tatcagtcta ctgctgctga attgcagcgt 7141 cttaagatga aggtaggtaa aagccgggag ttttaatcta ttctttctct acccccttcg 7201 tttggctttc ttttattttc tttttctgcg cttcgcgctc ccggagaaaa aaaaaaaaaa 7261 a //