locus-tag	class	description
JFL57_00015	COG0716	FMN binding
JFL57_00020	COG0445	tRNA wobble uridine modification
JFL57_00030	COG3312	ion transport
JFL57_00050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JFL57_00060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JFL57_00070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JFL57_00075	COG0271	Belongs to the BolA IbaG family
JFL57_00095	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFL57_00100	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFL57_00105	COG2871	sodium ion transport
JFL57_00115	COG1477	protein flavinylation
JFL57_00120	COG2991	Protein conserved in bacteria
JFL57_00130	COG0482	sulfurtransferase activity
JFL57_00145	COG3005	denitrification pathway
JFL57_00150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JFL57_00155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFL57_00170	COG1194	a g-specific adenine glycosylase
JFL57_00175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JFL57_00190	COG0471	metal ion transport
JFL57_00195	COG0583	DNA-binding transcription factor activity
JFL57_00200	COG3171	Protein conserved in bacteria
JFL57_00215	COG0762	integral membrane protein
JFL57_00230	COG2853	Lipoprotein
JFL57_00235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JFL57_00245	COG0363	glucosamine-6-phosphate deaminase activity
JFL57_00250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JFL57_00255	COG1218	3'(2'),5'-bisphosphate nucleotidase
JFL57_00260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JFL57_00295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JFL57_00305	COG1187	pseudouridine synthase activity
JFL57_00315	COG2900	Belongs to the SlyX family
JFL57_00320	COG0545	Peptidyl-prolyl cis-trans isomerase
JFL57_00325	COG2964	Protein conserved in bacteria
JFL57_00335	COG2923	Belongs to the DsrF TusC family
JFL57_00355	COG5295	Hep Hag repeat protein
JFL57_00365	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
JFL57_00370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JFL57_00400	COG3091	SprT-like family
JFL57_00415	COG0730	response to heat
JFL57_00430	COG0590	tRNA wobble adenosine to inosine editing
JFL57_00465	COG0859	PFAM glycosyl transferase family 9
JFL57_00475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JFL57_00485	COG1763	Mo-molybdopterin cofactor biosynthetic process
JFL57_00490	COG3086	response to oxidative stress
JFL57_00495	COG3026	antisigma factor binding
JFL57_00500	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JFL57_00505	COG1595	DNA-templated transcription, initiation
JFL57_00515	COG0800	Aldolase
JFL57_00525	COG2211	Major facilitator Superfamily
JFL57_00540	COG1028	Short-chain dehydrogenase reductase Sdr
JFL57_00545	COG2186	Transcriptional regulator
JFL57_00565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JFL57_00570	COG0456	acetyltransferase
JFL57_00575	COG0149	triose-phosphate isomerase activity
JFL57_00580	COG1519	Transferase
JFL57_00590	COG1132	(ABC) transporter
JFL57_00595	COG3718	enzyme involved in inositol metabolism
JFL57_00605	COG2826	transposase and inactivated derivatives, IS30 family
JFL57_00615	COG0823	Involved in the tonB-independent uptake of proteins
JFL57_00625	COG0673	inositol 2-dehydrogenase activity
JFL57_00630	COG1879	ABC-type sugar transport system periplasmic component
JFL57_00635	COG1879	ABC-type sugar transport system periplasmic component
JFL57_00640	COG1129	ABC transporter
JFL57_00645	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_00660	COG0673	inositol 2-dehydrogenase activity
JFL57_00665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JFL57_00670	COG0531	amino acid
JFL57_00675	COG1982	Orn Lys Arg decarboxylase major
JFL57_00685	COG0425	Belongs to the sulfur carrier protein TusA family
JFL57_00690	COG1739	Uncharacterized protein family UPF0029
JFL57_00695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JFL57_00750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFL57_00760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JFL57_00765	COG1737	Transcriptional regulator
JFL57_00770	COG1879	ABC-type sugar transport system periplasmic component
JFL57_00775	COG1129	ABC transporter
JFL57_00780	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_00785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JFL57_00790	COG1940	carbohydrate kinase activity
JFL57_00795	COG0698	ribose 5-phosphate isomerase
JFL57_00820	COG3068	Protein conserved in bacteria
JFL57_00830	COG1349	DNA-binding transcription factor activity
JFL57_00835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JFL57_00850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JFL57_00870	COG1929	Belongs to the glycerate kinase type-1 family
JFL57_00875	COG2610	gluconate transmembrane transporter activity
JFL57_00880	COG3835	regulator
JFL57_00905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JFL57_00915	COG1447	Phosphotransferase system cellobiose-specific component IIA
JFL57_00920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFL57_00925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JFL57_00930	COG1446	asparaginase
JFL57_00935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFL57_00945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JFL57_00955	COG0501	Belongs to the peptidase M48B family
JFL57_00965	COG0814	amino acid
JFL57_00970	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JFL57_00975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFL57_00990	COG0495	leucyl-tRNA aminoacylation
JFL57_00995	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JFL57_01000	COG1466	dna polymerase III delta subunit
JFL57_01005	COG2884	Cell division ATP-binding protein ftsE
JFL57_01010	COG2177	Part of the ABC transporter FtsEX involved in
JFL57_01015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFL57_01020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JFL57_01025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFL57_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFL57_01035	COG1120	ATPase activity
JFL57_01050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFL57_01060	COG3691	Protein conserved in bacteria
JFL57_01065	COG1741	Belongs to the pirin family
JFL57_01070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFL57_01085	COG3850	Histidine kinase
JFL57_01090	COG3062	negative regulation of establishment of protein localization
JFL57_01095	COG0243	molybdopterin cofactor binding
JFL57_01100	COG0437	4 iron, 4 sulfur cluster binding
JFL57_01105	COG0348	domain, Protein
JFL57_01110	COG3043	anaerobic respiration
JFL57_01115	COG3005	denitrification pathway
JFL57_01120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFL57_01120	COG0047	phosphoribosylformylglycinamidine synthase activity
JFL57_01150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JFL57_01150	COG0475	glutathione-regulated potassium exporter activity
JFL57_01155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JFL57_01170	COG2183	response to ionizing radiation
JFL57_01175	COG1114	Component of the transport system for branched-chain amino acids
JFL57_01185	COG1040	competence protein
JFL57_01195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JFL57_01205	COG0470	DNA polymerase III
JFL57_01210	COG0084	hydrolase, TatD family'
JFL57_01220	COG1253	flavin adenine dinucleotide binding
JFL57_01225	COG2826	transposase and inactivated derivatives, IS30 family
JFL57_01230	COG2826	transposase and inactivated derivatives, IS30 family
JFL57_01245	COG1584	GPR1 FUN34 yaaH family protein
JFL57_01250	COG2814	Major facilitator Superfamily
JFL57_01270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFL57_01275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JFL57_01285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JFL57_01340	COG4381	Mu-like prophage protein gp46
JFL57_01405	COG4397	Mu-like prophage major head subunit gpT
JFL57_01415	COG2369	cell adhesion
JFL57_01420	COG4383	Mu-like prophage protein gp29
JFL57_01455	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFL57_01470	COG3561	AntA/AntB antirepressor
JFL57_01480	COG4382	Mu-like prophage protein Gp16
JFL57_01510	COG2842	Transposition protein
JFL57_01530	COG2801	Transposase and inactivated derivatives
JFL57_01545	COG4178	(ABC) transporter
JFL57_01550	COG1328	CTP reductase activity
JFL57_01550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JFL57_01555	COG0602	queuosine metabolic process
JFL57_01560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JFL57_01575	COG0697	spore germination
JFL57_01580	COG4750	Nucleotidyl transferase
JFL57_01585	COG3475	LICD family
JFL57_01590	COG0194	GDP metabolic process
JFL57_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFL57_01605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JFL57_01610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JFL57_01640	COG0235	Class ii aldolase
JFL57_01650	COG1070	Carbohydrate kinase
JFL57_01655	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
JFL57_01660	COG0738	Major facilitator superfamily
JFL57_01665	COG1349	DNA-binding transcription factor activity
JFL57_01675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JFL57_01680	COG4942	peptidase
JFL57_01685	COG2861	carbohydrate metabolic process
JFL57_01690	COG1522	sequence-specific DNA binding
JFL57_01700	COG1285	pathogenesis
JFL57_01705	COG0360	Binds together with S18 to 16S ribosomal RNA
JFL57_01715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JFL57_01725	COG1473	amidohydrolase
JFL57_01740	COG0387	Pfam Sodium calcium exchanger
JFL57_01750	COG1702	phosphate starvation-inducible protein PhoH
JFL57_01760	COG1444	tRNA N-acetyltransferase activity
JFL57_01770	COG1966	Carbon starvation protein
JFL57_01785	COG3116	cell division
JFL57_01790	COG0768	penicillin binding
JFL57_01795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JFL57_01800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JFL57_01820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JFL57_01830	COG1181	Belongs to the D-alanine--D-alanine ligase family
JFL57_01835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JFL57_01840	COG0849	cell division
JFL57_01845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JFL57_01855	COG0077	Prephenate dehydratase
JFL57_01855	COG1605	Chorismate mutase
JFL57_01870	COG1496	oxidoreductase activity
JFL57_01875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JFL57_01890	COG0488	(ABC) transporter
JFL57_01905	COG4172	Belongs to the ABC transporter superfamily
JFL57_01910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFL57_01915	COG0601	transmembrane transport
JFL57_01925	COG4166	transmembrane transport
JFL57_01930	COG0569	domain protein
JFL57_01935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JFL57_01940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JFL57_01945	COG2610	gluconate transmembrane transporter activity
JFL57_01950	COG3265	gluconokinase activity
JFL57_01955	COG2358	TRAP transporter, solute receptor (TAXI family
JFL57_01980	COG2937	Belongs to the GPAT DAPAT family
JFL57_02020	COG4133	protoheme IX ABC transporter activity
JFL57_02025	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFL57_02030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFL57_02035	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFL57_02040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JFL57_02045	COG1138	Cytochrome C-type biogenesis protein
JFL57_02065	COG5002	protein histidine kinase activity
JFL57_02065	COG2198	Histidine kinase
JFL57_02065	COG0784	Response regulator, receiver
JFL57_02070	COG1426	Protein conserved in bacteria
JFL57_02080	COG0124	histidyl-tRNA synthetase
JFL57_02085	COG2976	Protein conserved in bacteria
JFL57_02100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JFL57_02105	COG2860	membrane
JFL57_02120	COG0758	DNA mediated transformation
JFL57_02125	COG0742	ribosomal rna small subunit methyltransferase
JFL57_02130	COG0552	protein localization to endoplasmic reticulum
JFL57_02135	COG0728	peptidoglycan biosynthetic process
JFL57_02150	COG0174	glutamine synthetase
JFL57_02155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JFL57_02155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JFL57_02170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JFL57_02170	COG0519	Catalyzes the synthesis of GMP from XMP
JFL57_02235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFL57_02250	COG4783	chaperone-mediated protein folding
JFL57_02280	COG0326	Molecular chaperone. Has ATPase activity
JFL57_02290	COG0675	Transposase, IS605 OrfB family
JFL57_02300	COG2091	lysine biosynthetic process via aminoadipic acid
JFL57_02330	COG1459	type II secretion system
JFL57_02335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JFL57_02345	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JFL57_02350	COG1115	amino acid carrier protein
JFL57_02355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JFL57_02360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JFL57_02370	COG0281	malic enzyme
JFL57_02370	COG0280	phosphate acetyltransferase
JFL57_02375	COG1027	Aspartate ammonia-lyase
JFL57_02395	COG3078	GTPase activator activity
JFL57_02405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFL57_02420	COG0626	cystathionine gamma-synthase activity
JFL57_02425	COG0450	alkyl hydroperoxide reductase
JFL57_02455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JFL57_02460	COG1053	succinate dehydrogenase
JFL57_02475	COG0675	Transposase, IS605 OrfB family
JFL57_02480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JFL57_02485	COG4608	Belongs to the ABC transporter superfamily
JFL57_02510	COG2350	Protein conserved in bacteria
JFL57_02515	COG1607	acyl-coa hydrolase
JFL57_02535	COG2927	DNA polymerase III (CHI subunit)
JFL57_02545	COG3177	Filamentation induced by cAMP protein fic
JFL57_02580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JFL57_02585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JFL57_02590	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JFL57_02595	COG1940	carbohydrate kinase activity
JFL57_02625	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_02645	COG0246	Mannitol dehydrogenase
JFL57_02650	COG3722	fumarate hydratase activity
JFL57_02655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JFL57_02680	COG3069	C4-dicarboxylate transmembrane transporter activity
JFL57_02685	COG1473	amidohydrolase
JFL57_02695	COG0681	Belongs to the peptidase S26 family
JFL57_02725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFL57_02730	COG5295	Hep Hag repeat protein
JFL57_02730	COG5295	Hep Hag repeat protein
JFL57_02735	COG2095	MarC family integral membrane protein
JFL57_02745	COG4545	Glutaredoxin-related protein
JFL57_02820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JFL57_02840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JFL57_02865	COG4383	Mu-like prophage protein gp29
JFL57_02870	COG1560	Kdo2-lipid A biosynthetic process
JFL57_02875	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JFL57_02875	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JFL57_02880	COG1393	Belongs to the ArsC family
JFL57_02890	COG1876	peptidase activity
JFL57_02895	COG0494	nUDIX hydrolase
JFL57_02900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JFL57_02915	COG4214	carbohydrate transport
JFL57_02920	COG1129	ABC transporter
JFL57_02925	COG4213	ABC transporter substrate-binding protein
JFL57_02935	COG1070	Carbohydrate kinase
JFL57_02955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFL57_02960	COG0328	RNA-DNA hybrid ribonuclease activity
JFL57_02965	COG1482	cell wall glycoprotein biosynthetic process
JFL57_02975	COG3716	PTS system mannose fructose sorbose family IID component
JFL57_02980	COG3715	PTS system
JFL57_02985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFL57_02985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFL57_02990	COG2926	Belongs to the UPF0265 family
JFL57_03010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFL57_03015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFL57_03020	COG2267	carboxylic ester hydrolase activity
JFL57_03025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JFL57_03035	COG0436	Aminotransferase
JFL57_03045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JFL57_03055	COG1442	glycosyl transferase family 8
JFL57_03060	COG1216	Glycosyl transferase, family 2
JFL57_03080	COG3842	ATPase activity
JFL57_03090	COG1840	ABC-type Fe3 transport system, periplasmic component
JFL57_03095	COG1840	ABC-type Fe3 transport system, periplasmic component
JFL57_03115	COG0385	Bile acid
JFL57_03135	COG0497	DNA recombination
JFL57_03145	COG0251	oxidation-reduction process
JFL57_03165	COG2835	tetraacyldisaccharide 4'-kinase activity
JFL57_03170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JFL57_03175	COG0322	excinuclease ABC activity
JFL57_03180	COG2314	TM2 domain
JFL57_03190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JFL57_03195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JFL57_03205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFL57_03210	COG0004	ammonium transporteR
JFL57_03225	COG1162	GTPase activity
JFL57_03230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFL57_03235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JFL57_03240	COG2190	(PTS) system
JFL57_03245	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JFL57_03250	COG0508	dehydrogenase complex catalyzes the overall conversion of
JFL57_03255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFL57_03260	COG2932	Transcriptional regulator
JFL57_03270	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JFL57_03285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFL57_03290	COG0469	pyruvate kinase activity
JFL57_03300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFL57_03305	COG2833	Protein of unknown function (DUF455)
JFL57_03315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JFL57_03320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JFL57_03325	COG4988	ABC transporter
JFL57_03330	COG0492	ferredoxin-NADP+ reductase activity
JFL57_03335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JFL57_03340	COG3219	Protein conserved in bacteria
JFL57_03345	COG3220	belongs to the UPF0276 family
JFL57_03355	COG2259	Doxx family
JFL57_03360	COG1882	Formate acetyltransferase
JFL57_03365	COG2116	formate transmembrane transporter activity
JFL57_03370	COG0537	adenosine 5'-monophosphoramidase activity
JFL57_03380	COG1472	Belongs to the glycosyl hydrolase 3 family
JFL57_03390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JFL57_03405	COG1077	Cell shape determining protein MreB Mrl
JFL57_03410	COG1792	Involved in formation and maintenance of cell shape
JFL57_03415	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JFL57_03420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JFL57_03425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JFL57_03430	COG3956	TIGRFAM MazG family protein
JFL57_03470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JFL57_03480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFL57_03485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JFL57_03490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JFL57_03505	COG4796	Type ii and iii secretion system protein
JFL57_03520	COG4972	Pilus assembly protein
JFL57_03525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JFL57_03530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JFL57_03535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFL57_03550	COG3283	Transcriptional regulator of aromatic amino acids metabolism
JFL57_03565	COG1476	TRANSCRIPTIONal
JFL57_03570	COG0287	Prephenate dehydrogenase
JFL57_03570	COG1605	Chorismate mutase
JFL57_03575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JFL57_03585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFL57_03590	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFL57_03595	COG1028	Short-chain dehydrogenase reductase Sdr
JFL57_03610	COG3730	PTS system glucitol sorbitol-specific
JFL57_03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFL57_03640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFL57_03645	COG0006	proline dipeptidase activity
JFL57_03665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JFL57_03675	COG0560	Phosphoserine phosphatase
JFL57_03680	COG1666	GTP binding
JFL57_03690	COG0848	biopolymer transport protein
JFL57_03695	COG0811	peptide transport
JFL57_03700	COG0165	Argininosuccinate lyase
JFL57_03705	COG1295	ribonuclease BN
JFL57_03720	COG1737	Transcriptional regulator
JFL57_03725	COG2731	YhcH YjgK YiaL family protein
JFL57_03735	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JFL57_03745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFL57_03760	COG0513	Belongs to the DEAD box helicase family
JFL57_03770	COG1083	cytidylyl-transferase
JFL57_03775	COG1088	dTDP-glucose 4,6-dehydratase activity
JFL57_03780	COG1620	l-lactate permease
JFL57_03785	COG0247	lactate metabolic process
JFL57_03790	COG1139	Iron-sulfur cluster binding protein
JFL57_03795	COG1556	Lactate utilization protein
JFL57_03805	COG0745	RESPONSE REGULATOR receiver
JFL57_03815	COG1530	ribonuclease E activity
JFL57_03825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFL57_03825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFL57_03830	COG0210	DNA helicase
JFL57_03855	COG0748	coenzyme F420 binding
JFL57_03860	COG3721	Heme iron utilization protein
JFL57_03865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JFL57_03870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JFL57_03875	COG3475	LICD family
JFL57_03880	COG1629	transport
JFL57_03885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JFL57_03890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFL57_03895	COG2062	phosphohistidine phosphatase, SixA
JFL57_03905	COG1199	ATP-dependent helicase activity
JFL57_03910	COG1214	PFAM Peptidase M22, glycoprotease
JFL57_03915	COG0318	PFAM AMP-dependent synthetase and ligase
JFL57_03920	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JFL57_03925	COG2823	Periplasmic or secreted lipoprotein
JFL57_03930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JFL57_03935	COG0792	nuclease activity
JFL57_03950	COG0009	L-threonylcarbamoyladenylate synthase
JFL57_03965	COG1538	Outer membrane efflux protein
JFL57_03970	COG1349	DNA-binding transcription factor activity
JFL57_03980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFL57_03985	COG0738	Major facilitator superfamily
JFL57_03995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JFL57_04010	COG2969	positive regulation of protein catabolic process
JFL57_04020	COG1940	carbohydrate kinase activity
JFL57_04025	COG1414	Transcriptional regulator
JFL57_04035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFL57_04040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFL57_04045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFL57_04050	COG1129	ABC transporter
JFL57_04070	COG1879	ABC-type sugar transport system periplasmic component
JFL57_04075	COG1129	ABC transporter
JFL57_04080	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_04090	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JFL57_04095	COG3623	hexulose-6-phosphate isomerase
JFL57_04100	COG0235	Class ii aldolase
JFL57_04105	COG0561	phosphatase activity
JFL57_04110	COG2267	carboxylic ester hydrolase activity
JFL57_04125	COG0778	Nitroreductase
JFL57_04130	COG3691	Protein conserved in bacteria
JFL57_04135	COG0814	amino acid
JFL57_04140	COG3842	ATPase activity
JFL57_04150	COG1840	ABC-type Fe3 transport system, periplasmic component
JFL57_04155	COG0277	FAD linked oxidase domain protein
JFL57_04165	COG0788	formyltetrahydrofolate deformylase activity
JFL57_04175	COG1757	Na H antiporter
JFL57_04190	COG0339	signal peptide processing
JFL57_04195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JFL57_04200	COG1757	Na H antiporter
JFL57_04205	COG1609	Transcriptional regulator
JFL57_04205	COG2207	Transcriptional regulator
JFL57_04215	COG4166	transmembrane transport
JFL57_04220	COG0488	(ABC) transporter
JFL57_04230	COG4172	Belongs to the ABC transporter superfamily
JFL57_04235	COG4172	Belongs to the ABC transporter superfamily
JFL57_04240	COG4171	peptide transport system, permease
JFL57_04245	COG4168	peptide transport system, permease
JFL57_04250	COG4166	transmembrane transport
JFL57_04255	COG3106	COG3106 Predicted ATPase
JFL57_04265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JFL57_04270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFL57_04275	COG0187	DNA topoisomerase II activity
JFL57_04280	COG2814	Major facilitator Superfamily
JFL57_04285	COG2252	PERMEase
JFL57_04300	COG0814	amino acid
JFL57_04315	COG0857	belongs to the CobB CobQ family
JFL57_04315	COG0280	phosphate acetyltransferase
JFL57_04335	COG0243	molybdopterin cofactor binding
JFL57_04340	COG3005	denitrification pathway
JFL57_04365	COG0307	riboflavin synthase, alpha
JFL57_04370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JFL57_04375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JFL57_04380	COG3105	Protein conserved in bacteria
JFL57_04385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFL57_04390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JFL57_04395	COG0515	serine threonine protein kinase
JFL57_04405	COG0779	Required for maturation of 30S ribosomal subunits
JFL57_04410	COG0195	Participates in both transcription termination and antitermination
JFL57_04430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JFL57_04440	COG3112	Uncharacterised protein family (UPF0231)
JFL57_04445	COG0316	Belongs to the HesB IscA family
JFL57_04450	COG0024	Methionine aminopeptidase
JFL57_04465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JFL57_04470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JFL57_04475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JFL57_04480	COG1280	lysine exporter protein (LysE YggA)
JFL57_04490	COG0708	Exodeoxyribonuclease III
JFL57_04495	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
JFL57_04500	COG1448	Aminotransferase
JFL57_04505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JFL57_04510	COG0288	reversible hydration of carbon dioxide
JFL57_04525	COG0135	phosphoribosylanthranilate isomerase activity
JFL57_04525	COG0134	indole-3-glycerol-phosphate synthase activity
JFL57_04535	COG0512	Glutamine amidotransferase of anthranilate synthase
JFL57_04540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFL57_04545	COG0616	signal peptide processing
JFL57_04565	COG3118	belongs to the thioredoxin family
JFL57_04570	COG2252	PERMEase
JFL57_04575	COG3101	peptidyl-lysine hydroxylation
JFL57_04580	COG1131	(ABC) transporter
JFL57_04585	COG0842	Transport permease protein
JFL57_04590	COG1611	Belongs to the LOG family
JFL57_04595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFL57_04595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFL57_04600	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JFL57_04605	COG3098	single-species biofilm formation
JFL57_04615	COG3140	Belongs to the UPF0181 family
JFL57_04620	COG1278	Cold shock
JFL57_04630	COG1067	ATP-dependent peptidase activity
JFL57_04655	COG0037	tRNA processing
JFL57_04660	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JFL57_04665	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JFL57_04675	COG3586	endonuclease activity
JFL57_04680	COG0697	spore germination
JFL57_04705	COG1943	Transposase
JFL57_04715	COG2925	Exonuclease
JFL57_04735	COG0586	Pfam SNARE associated Golgi protein
JFL57_04755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JFL57_04760	COG0589	response to stress
JFL57_04765	COG0285	dihydrofolate synthase activity
JFL57_04775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFL57_04780	COG0613	PHP domain protein
JFL57_04785	COG0308	aminopeptidase N
JFL57_04795	COG0297	glycogen (starch) synthase activity
JFL57_04805	COG1523	belongs to the glycosyl hydrolase 13 family
JFL57_04810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JFL57_04815	COG1640	4-alpha-glucanotransferase
JFL57_04825	COG0612	Peptidase, M16
JFL57_04870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFL57_04870	COG0301	tRNA thio-modification
JFL57_04875	COG1722	exodeoxyribonuclease VII activity
JFL57_04880	COG0142	geranyltranstransferase activity
JFL57_04890	COG2431	L-lysine efflux transmembrane transporter activity
JFL57_04895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JFL57_04900	COG0616	signal peptide processing
JFL57_04905	COG0778	Nitroreductase
JFL57_04915	COG0303	'Molybdopterin
JFL57_04920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JFL57_04925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JFL57_04930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFL57_04935	COG0163	prenyltransferase activity
JFL57_04945	COG1286	toxin biosynthetic process
JFL57_04955	COG0517	IMP dehydrogenase activity
JFL57_04955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JFL57_04960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JFL57_04965	COG1528	Iron-storage protein
JFL57_04970	COG1528	Iron-storage protein
JFL57_04975	COG1349	DNA-binding transcription factor activity
JFL57_04985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFL57_04995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JFL57_05000	COG1074	ATP-dependent DNA helicase activity
JFL57_05010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFL57_05015	COG0825	malonyl-CoA metabolic process
JFL57_05040	COG0305	Participates in initiation and elongation during chromosome replication
JFL57_05045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JFL57_05050	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFL57_05060	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFL57_05065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFL57_05085	COG1714	RDD family
JFL57_05100	COG3133	Outer membrane lipoprotein
JFL57_05110	COG3102	Protein conserved in bacteria
JFL57_05120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JFL57_05135	COG0567	Dehydrogenase, E1 component
JFL57_05145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFL57_05150	COG0633	Ferredoxin
JFL57_05155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JFL57_05160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JFL57_05165	COG1346	cytolysis
JFL57_05170	COG1380	Effector of murein hydrolase LrgA
JFL57_05175	COG1525	nuclease
JFL57_05185	COG2166	iron-sulfur cluster assembly
JFL57_05190	COG3077	Addiction module antitoxin, RelB DinJ family
JFL57_05195	COG3041	Addiction module toxin RelE StbE family
JFL57_05210	COG4453	Protein conserved in bacteria
JFL57_05220	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JFL57_05225	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JFL57_05235	COG0539	negative regulation of cytoplasmic translation
JFL57_05240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JFL57_05245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFL57_05260	COG0750	zinc metalloprotease
JFL57_05265	COG0575	Belongs to the CDS family
JFL57_05275	COG5413	integral membrane protein
JFL57_05280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JFL57_05290	COG0528	UMP kinase activity
JFL57_05305	COG0653	protein targeting
JFL57_05310	COG0494	nUDIX hydrolase
JFL57_05315	COG1643	Atp-dependent helicase
JFL57_05320	COG2707	UPF0756 membrane protein
JFL57_05340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JFL57_05345	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JFL57_05355	COG1534	Rna-binding protein
JFL57_05360	COG1393	Belongs to the ArsC family
JFL57_05380	COG5295	Hep Hag repeat protein
JFL57_05385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JFL57_05390	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JFL57_05395	COG1178	ABC-type Fe3 transport system permease component
JFL57_05400	COG4143	(ABC) transporter
JFL57_05415	COG2056	Na+-H+ antiporter family
JFL57_05430	COG1595	DNA-templated transcription, initiation
JFL57_05475	COG1132	(ABC) transporter
JFL57_05480	COG2333	competence protein COMEC
JFL57_05480	COG0658	competence protein
JFL57_05485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JFL57_05490	COG0617	tRNA 3'-terminal CCA addition
JFL57_05495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JFL57_05500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JFL57_05510	COG0314	molybdopterin synthase activity
JFL57_05515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JFL57_05520	COG0315	cyclic pyranopterin monophosphate synthase activity
JFL57_05525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JFL57_05530	COG1609	Transcriptional regulator
JFL57_05535	COG0583	DNA-binding transcription factor activity
JFL57_05550	COG0739	heme binding
JFL57_05555	COG1121	(ABC) transporter
JFL57_05560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFL57_05565	COG1115	amino acid carrier protein
JFL57_05570	COG1940	carbohydrate kinase activity
JFL57_05575	COG0671	phosphoesterase, PA-phosphatase related
JFL57_05585	COG0277	FAD linked oxidase domain protein
JFL57_05585	COG0247	lactate metabolic process
JFL57_05605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JFL57_05610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFL57_05615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFL57_05615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFL57_05625	COG1687	branched-chain amino acid
JFL57_05630	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JFL57_05635	COG0583	DNA-binding transcription factor activity
JFL57_05645	COG1438	arginine binding
JFL57_05650	COG1090	epimerase
JFL57_05655	COG5295	Hep Hag repeat protein
JFL57_05670	COG4656	Part of a membrane complex involved in electron transport
JFL57_05675	COG4658	electron transport chain
JFL57_05690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JFL57_05695	COG0733	neurotransmitter:sodium symporter activity
JFL57_05705	COG3008	intermembrane lipid transfer
JFL57_05710	COG2995	paraquat-inducible protein a
JFL57_05715	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JFL57_05720	COG0793	Belongs to the peptidase S41A family
JFL57_05725	COG2989	Protein conserved in bacteria
JFL57_05730	COG3108	Peptidase M15
JFL57_05735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JFL57_05750	COG2949	membrane
JFL57_05765	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JFL57_05770	COG3683	transport system, periplasmic component
JFL57_05775	COG0802	atpase or kinase
JFL57_05780	COG1388	LysM domain
JFL57_05780	COG0860	N-Acetylmuramoyl-L-alanine amidase
JFL57_05785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JFL57_05810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFL57_05815	COG3842	ATPase activity
JFL57_05820	COG1176	ABC-type spermidine putrescine transport system, permease component I
JFL57_05825	COG1177	transmembrane transport
JFL57_05830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JFL57_05835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JFL57_05845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFL57_05850	COG2824	Alkylphosphonate utilization operon protein PhnA
JFL57_05855	COG0814	amino acid
JFL57_05860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JFL57_05865	COG5007	Belongs to the BolA IbaG family
JFL57_05870	COG3113	response to antibiotic
JFL57_05875	COG2854	intermembrane phospholipid transfer
JFL57_05880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JFL57_05885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JFL57_05890	COG1127	ABC transporter
JFL57_05895	COG3117	lipopolysaccharide transmembrane transporter activity
JFL57_05900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JFL57_05905	COG1137	ATPase activity
JFL57_05910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFL57_05920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFL57_05920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFL57_05925	COG0489	protein tyrosine kinase activity
JFL57_05935	COG3041	Addiction module toxin RelE StbE family
JFL57_05940	COG3077	Addiction module antitoxin, RelB DinJ family
JFL57_05945	COG3381	protein complex oligomerization
JFL57_05950	COG2249	NAD(P)H dehydrogenase (quinone) activity
JFL57_05960	COG0330	HflC and HflK could
JFL57_05970	COG0511	ligase activity, forming carbon-carbon bonds
JFL57_05975	COG0439	Biotin carboxylase
JFL57_05980	COG3924	membrane
JFL57_05985	COG4145	pantothenate transmembrane transporter activity
JFL57_06030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JFL57_06065	COG0504	CTP synthase activity
JFL57_06080	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JFL57_06090	COG0805	protein transport
JFL57_06095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JFL57_06105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JFL57_06120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JFL57_06130	COG3210	domain, Protein
JFL57_06190	COG2732	(Barnase) inhibitor
JFL57_06600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFL57_06615	COG0667	Aldo Keto reductase
JFL57_06630	COG2132	Multicopper oxidase
JFL57_06675	COG0629	single-stranded DNA binding
JFL57_06705	COG0305	Participates in initiation and elongation during chromosome replication
JFL57_06720	COG0795	lipopolysaccharide-transporting ATPase activity
JFL57_06725	COG0795	lipopolysaccharide-transporting ATPase activity
JFL57_06735	COG1349	DNA-binding transcription factor activity
JFL57_06740	COG0247	lactate metabolic process
JFL57_06750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JFL57_06755	COG2271	Major facilitator Superfamily
JFL57_06760	COG0584	glycerophosphoryl diester phosphodiesterase
JFL57_06765	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JFL57_06775	COG0494	nUDIX hydrolase
JFL57_06785	COG2867	negative regulation of translational initiation
JFL57_06790	COG0193	aminoacyl-tRNA hydrolase activity
JFL57_06795	COG0012	GTP binding
JFL57_06800	COG0346	lactoylglutathione lyase activity
JFL57_06805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFL57_06815	COG0204	Acyl-transferase
JFL57_06820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFL57_06825	COG0210	DNA helicase
JFL57_06835	COG0583	DNA-binding transcription factor activity
JFL57_06840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFL57_06845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JFL57_06850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFL57_06860	COG0456	acetyltransferase
JFL57_06865	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
JFL57_06870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JFL57_06875	COG0330	HflC and HflK could
JFL57_06880	COG0330	HflC and HflK could
JFL57_06910	COG0675	Transposase, IS605 OrfB family
JFL57_06935	COG0751	glycine-tRNA ligase activity
JFL57_06950	COG1522	sequence-specific DNA binding
JFL57_06955	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JFL57_06960	COG3025	triphosphatase activity
JFL57_06965	COG1392	Phosphate transport regulator
JFL57_06970	COG0306	phosphate transporter
JFL57_06975	COG4991	sh3 domain protein
JFL57_06980	COG0617	tRNA 3'-terminal CCA addition
JFL57_06990	COG0484	heat shock protein binding
JFL57_07010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFL57_07015	COG3063	Type IV pilus biogenesis stability protein PilW
JFL57_07025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JFL57_07035	COG1560	Kdo2-lipid A biosynthetic process
JFL57_07040	COG0730	response to heat
JFL57_07045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
JFL57_07055	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JFL57_07055	COG3264	Mechanosensitive ion channel
JFL57_07060	COG0318	PFAM AMP-dependent synthetase and ligase
JFL57_07065	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JFL57_07070	COG0596	Alpha beta hydrolase
JFL57_07075	COG0716	FMN binding
JFL57_07080	COG0735	belongs to the Fur family
JFL57_07085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JFL57_07090	COG0083	homoserine kinase activity
JFL57_07095	COG0460	homoserine dehydrogenase
JFL57_07095	COG0527	aspartate kinase activity
JFL57_07105	COG1570	exodeoxyribonuclease VII activity
JFL57_07125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JFL57_07130	COG4149	molybdate abc transporter
JFL57_07135	COG0725	ABC transporter, periplasmic molybdate-binding protein
JFL57_07155	COG5295	Hep Hag repeat protein
JFL57_07170	COG4974	Belongs to the 'phage' integrase family
JFL57_07175	COG2814	Major facilitator Superfamily
JFL57_07180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFL57_07190	COG3061	Opacity-associated protein A
JFL57_07190	COG3266	domain, Protein
JFL57_07195	COG1509	lysine 2,3-aminomutase activity
JFL57_07220	COG1561	YicC-like family, N-terminal region
JFL57_07225	COG0354	folic acid binding
JFL57_07230	COG0513	Belongs to the DEAD box helicase family
JFL57_07235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JFL57_07240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JFL57_07245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JFL57_07260	COG0545	Peptidyl-prolyl cis-trans isomerase
JFL57_07265	COG0488	(ABC) transporter
JFL57_07280	COG0442	prolyl-tRNA aminoacylation
JFL57_07310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFL57_07320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFL57_07325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFL57_07330	COG1862	Preprotein translocase
JFL57_07335	COG0343	queuine tRNA-ribosyltransferase activity
JFL57_07345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFL57_07350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFL57_07350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFL57_07355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFL57_07365	COG0826	peptidase U32
JFL57_07370	COG1793	dna ligase
JFL57_07380	COG3028	Belongs to the UPF0307 family
JFL57_07385	COG0312	modulator of DNA gyrase
JFL57_07390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JFL57_07400	COG3250	beta-galactosidase activity
JFL57_07415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JFL57_07435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFL57_07445	COG0626	cystathionine gamma-synthase activity
JFL57_07545	COG1484	DNA-dependent DNA replication
JFL57_07550	COG0582	viral genome integration into host DNA
JFL57_07605	COG1476	TRANSCRIPTIONal
JFL57_07620	COG3152	Membrane
JFL57_07625	COG3621	Patatin-like phospholipase
JFL57_07720	COG0675	Transposase, IS605 OrfB family
JFL57_07760	COG4453	Protein conserved in bacteria
JFL57_07820	COG3210	domain, Protein
JFL57_07820	COG3210	domain, Protein
JFL57_07825	COG2831	hemolysin activation secretion protein
JFL57_07830	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JFL57_07835	COG1803	Methylglyoxal synthase
JFL57_07840	COG1289	transmembrane transporter activity
JFL57_07850	COG2890	protein-(glutamine-N5) methyltransferase activity
JFL57_07855	COG0628	permease
JFL57_07865	COG0521	Mo-molybdopterin cofactor biosynthetic process
JFL57_07870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JFL57_07890	COG2990	Protein conserved in bacteria
JFL57_07895	COG0137	argininosuccinate synthase activity
JFL57_07900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFL57_08035	COG0675	Transposase, IS605 OrfB family
JFL57_08095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JFL57_08100	COG3645	SOS response
JFL57_08155	COG3617	BRO family, N-terminal domain
JFL57_08185	COG3723	Recombinational DNA repair protein, rece pathway
JFL57_08210	COG0202	RNA polymerase activity
JFL57_08220	COG0582	viral genome integration into host DNA
JFL57_08230	COG0659	secondary active sulfate transmembrane transporter activity
JFL57_08235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JFL57_08240	COG4137	Cytochrome C assembly protein
JFL57_08245	COG4536	flavin adenine dinucleotide binding
JFL57_08250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JFL57_08265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JFL57_08275	COG0248	Ppx GppA phosphatase
JFL57_08285	COG0729	surface antigen
JFL57_08290	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFL57_08320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JFL57_08325	COG0606	chelatase, subunit chli
JFL57_08340	COG2920	part of a sulfur-relay system
JFL57_08350	COG1121	(ABC) transporter
JFL57_08355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFL57_08360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFL57_08365	COG0799	negative regulation of ribosome biogenesis
JFL57_08375	COG0768	penicillin binding
JFL57_08380	COG0772	Belongs to the SEDS family
JFL57_08390	COG1686	Belongs to the peptidase S11 family
JFL57_08420	COG1297	OPT oligopeptide transporter protein
JFL57_08425	COG0746	molybdenum cofactor guanylyltransferase activity
JFL57_08430	COG3084	Protein conserved in bacteria
JFL57_08435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFL57_08440	COG3085	chromosome segregation
JFL57_08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFL57_08470	COG2176	DNA-directed DNA polymerase activity
JFL57_08475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFL57_08480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFL57_08485	COG1609	Transcriptional regulator
JFL57_08505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JFL57_08510	COG0228	four-way junction DNA binding
JFL57_08520	COG2364	Membrane
JFL57_08525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFL57_08530	COG0813	purine-nucleoside phosphorylase activity
JFL57_08535	COG2918	glutathione biosynthetic process
JFL57_08535	COG1181	Belongs to the D-alanine--D-alanine ligase family
JFL57_08540	COG0633	Ferredoxin
JFL57_08545	COG0443	Heat shock 70 kDa protein
JFL57_08550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JFL57_08560	COG0822	iron-sulfur transferase activity
JFL57_08570	COG1959	2 iron, 2 sulfur cluster binding
JFL57_08575	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JFL57_08585	COG4797	methyltransferase
JFL57_08585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JFL57_08600	COG1530	ribonuclease E activity
JFL57_08605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFL57_08615	COG2081	HI0933 family
JFL57_08630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JFL57_08645	COG4795	General secretion pathway protein
JFL57_08650	COG2165	general secretion pathway protein
JFL57_08680	COG3064	Membrane
JFL57_08685	COG0848	biopolymer transport protein
JFL57_08690	COG0811	peptide transport
JFL57_08695	COG0824	Thioesterase
JFL57_08705	COG1294	oxidase, subunit
JFL57_08710	COG1271	oxidase subunit
JFL57_08720	COG4160	amino acid transport
JFL57_08725	COG4215	(ABC) transporter
JFL57_08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFL57_08735	COG1126	abc transporter atp-binding protein
JFL57_08740	COG4969	Belongs to the N-Me-Phe pilin family
JFL57_08745	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFL57_08750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JFL57_08755	COG0697	spore germination
JFL57_08770	COG0142	geranyltranstransferase activity
JFL57_08775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JFL57_08780	COG0215	cysteine-tRNA ligase activity
JFL57_08785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JFL57_08790	COG0084	hydrolase, TatD family'
JFL57_08805	COG2017	converts alpha-aldose to the beta-anomer
JFL57_08810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JFL57_08815	COG1085	galactose-1-phosphate uridylyltransferase
JFL57_08820	COG1609	Transcriptional regulator
JFL57_08825	COG1879	ABC-type sugar transport system periplasmic component
JFL57_08830	COG1129	ABC transporter
JFL57_08835	COG4211	Belongs to the binding-protein-dependent transport system permease family
JFL57_08840	COG1368	sulfuric ester hydrolase activity
JFL57_08845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JFL57_08850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JFL57_08855	COG1489	DNA binding
JFL57_08860	COG3083	sulfuric ester hydrolase activity
JFL57_08870	COG3081	Nucleoid-associated protein
JFL57_08875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFL57_08885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFL57_08890	COG1879	ABC-type sugar transport system periplasmic component
JFL57_08895	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_08900	COG1129	ABC transporter
JFL57_08910	COG1720	tRNA m6t6A37 methyltransferase activity
JFL57_08915	COG1575	Belongs to the MenA family. Type 1 subfamily
JFL57_08920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JFL57_08925	COG0471	metal ion transport
JFL57_08930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFL57_08935	COG0765	amino acid transport
JFL57_08940	COG1126	abc transporter atp-binding protein
JFL57_08955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JFL57_08965	COG0191	fructose-bisphosphate aldolase activity
JFL57_08970	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JFL57_08980	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JFL57_09010	COG0786	glutamate:sodium symporter activity
JFL57_09045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFL57_09055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JFL57_09060	COG2966	Psort location CytoplasmicMembrane, score
JFL57_09065	COG3610	response to peptide
JFL57_09070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JFL57_09075	COG0196	riboflavin kinase activity
JFL57_09085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JFL57_09095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JFL57_09110	COG2860	membrane
JFL57_09120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFL57_09140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JFL57_09150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JFL57_09165	COG0081	regulation of translation
JFL57_09180	COG1028	Short-chain dehydrogenase reductase Sdr
JFL57_09185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JFL57_09195	COG0416	fatty acid biosynthetic process
JFL57_09205	COG1399	metal-binding, possibly nucleic acid-binding protein
JFL57_09210	COG0705	Rhomboid family
JFL57_09225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JFL57_09230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFL57_09235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFL57_09240	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JFL57_09250	COG1045	serine acetyltransferase
JFL57_09265	COG0557	exoribonuclease II activity
JFL57_09270	COG3161	chorismate lyase activity
JFL57_09275	COG2258	MOSC domain
JFL57_09280	COG3978	acetolactate synthase activity
JFL57_09290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JFL57_09310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JFL57_09335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JFL57_09340	COG0592	DNA-directed DNA polymerase activity
JFL57_09345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFL57_09365	COG0706	membrane insertase activity
JFL57_09375	COG0783	Belongs to the Dps family
JFL57_09380	COG0512	Glutamine amidotransferase of anthranilate synthase
JFL57_09385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFL57_09390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFL57_09395	COG0251	oxidation-reduction process
JFL57_09400	COG1555	photosystem II stabilization
JFL57_09405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JFL57_09410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFL57_09415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JFL57_09420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JFL57_09470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFL57_09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFL57_09490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFL57_09495	COG1028	Short-chain dehydrogenase reductase Sdr
JFL57_09505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFL57_09515	COG4771	TonB-dependent receptor
JFL57_09515	COG1629	transport
JFL57_09520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JFL57_09525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFL57_09530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFL57_09535	COG1381	Involved in DNA repair and RecF pathway recombination
JFL57_09550	COG3172	ATPase kinase involved in NAD metabolism
JFL57_09555	COG2129	metallophosphoesterase
JFL57_09565	COG0202	RNA polymerase activity
JFL57_09580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JFL57_09590	COG0201	protein transport
JFL57_09600	COG1841	ribosomal large subunit assembly
JFL57_09665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JFL57_09670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JFL57_09675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JFL57_09685	COG0089	rRNA binding
JFL57_09700	COG0051	transcription antitermination factor activity, RNA binding
JFL57_09735	COG1129	ABC transporter
JFL57_09740	COG2390	Transcriptional regulator
JFL57_09745	COG1070	Carbohydrate kinase
JFL57_09755	COG3071	HemY protein
JFL57_09760	COG2959	enzyme of heme biosynthesis
JFL57_09780	COG2197	response regulator
JFL57_09785	COG0242	peptide deformylase activity
JFL57_09790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JFL57_09800	COG0569	domain protein
JFL57_09810	COG0583	DNA-binding transcription factor activity
JFL57_09815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JFL57_09815	COG0678	peroxiredoxin activity
JFL57_09825	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_09830	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFL57_09850	COG1914	H( )-stimulated, divalent metal cation uptake system
JFL57_09855	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JFL57_09860	COG1984	allophanate hydrolase subunit 2
JFL57_09865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JFL57_09870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFL57_09875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFL57_09880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFL57_09885	COG1063	alcohol dehydrogenase
JFL57_09890	COG2186	Transcriptional regulator
JFL57_09910	COG2610	gluconate transmembrane transporter activity
JFL57_09915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFL57_09920	COG3622	Belongs to the hyi family
JFL57_09925	COG0235	Class ii aldolase
JFL57_09930	COG3395	kinase activity
JFL57_09935	COG2084	Dehydrogenase
JFL57_09940	COG1349	DNA-binding transcription factor activity
JFL57_09955	COG0551	DNA topoisomerase type I activity
JFL57_09960	COG0009	L-threonylcarbamoyladenylate synthase
JFL57_09975	COG2195	Cleaves the N-terminal amino acid of tripeptides
JFL57_10000	COG3048	D-serine ammonia-lyase activity
JFL57_10005	COG2610	gluconate transmembrane transporter activity
JFL57_10010	COG0583	DNA-binding transcription factor activity
JFL57_10040	COG3070	regulator of competence-specific genes
JFL57_10050	COG0733	neurotransmitter:sodium symporter activity
JFL57_10055	COG0019	diaminopimelate decarboxylase activity
JFL57_10065	COG1965	Belongs to the frataxin family