locus-tag	class	description
FR848_00035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FR848_00075	COG0151	Belongs to the GarS family
FR848_00085	COG4191	Histidine kinase
FR848_00100	COG0776	regulation of translation
FR848_00105	COG3068	Protein conserved in bacteria
FR848_00125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FR848_00140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR848_00145	COG2104	thiamine diphosphate biosynthetic process
FR848_00155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FR848_00160	COG3706	GGDEF domain
FR848_00170	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR848_00175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR848_00210	COG0250	Participates in transcription elongation, termination and antitermination
FR848_00215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR848_00255	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FR848_00255	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FR848_00260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FR848_00290	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FR848_00300	COG1739	Uncharacterized protein family UPF0029
FR848_00345	COG0805	protein transport
FR848_00355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR848_00365	COG3165	ubiquinone biosynthetic process from chorismate
FR848_00375	COG1322	Protein conserved in bacteria
FR848_00380	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FR848_00385	COG0412	Dienelactone hydrolase
FR848_00400	COG0583	DNA-binding transcription factor activity
FR848_00410	COG0561	phosphatase activity
FR848_00415	COG2267	carboxylic ester hydrolase activity
FR848_00420	COG1280	lysine exporter protein (LysE YggA)
FR848_00430	COG1280	lysine exporter protein (LysE YggA)
FR848_00445	COG2050	protein possibly involved in aromatic compounds catabolism
FR848_00455	COG0598	Magnesium transport protein CorA
FR848_00460	COG0210	DNA helicase
FR848_00465	COG1011	Hydrolase
FR848_00485	COG5567	small periplasmic lipoprotein
FR848_00495	COG1228	amidohydrolase
FR848_00500	COG0477	Major facilitator Superfamily
FR848_00515	COG3072	Adenylate cyclase
FR848_00525	COG1587	Uroporphyrinogen-III synthase
FR848_00530	COG2959	enzyme of heme biosynthesis
FR848_00535	COG3071	HemY protein
FR848_00560	COG1113	amino acid transport
FR848_00580	COG2244	polysaccharide biosynthetic process
FR848_00585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FR848_00590	COG0456	acetyltransferase
FR848_00595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FR848_00600	COG1088	dTDP-glucose 4,6-dehydratase activity
FR848_00605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FR848_00610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FR848_00620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR848_00625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FR848_00630	COG3118	belongs to the thioredoxin family
FR848_00650	COG1397	ADP-ribosylglycohydrolase
FR848_00675	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FR848_00685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_00690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_00700	COG0583	DNA-binding transcription factor activity
FR848_00705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR848_00715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR848_00720	COG3978	acetolactate synthase activity
FR848_00740	COG3085	chromosome segregation
FR848_00815	COG0583	DNA-binding transcription factor activity
FR848_00830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FR848_00845	COG3443	Belongs to the bacterial solute-binding protein 9 family
FR848_00850	COG2207	Transcriptional regulator
FR848_00860	COG0371	Dehydrogenase
FR848_00865	COG1349	DNA-binding transcription factor activity
FR848_00875	COG0583	DNA-binding transcription factor activity
FR848_00880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_00885	COG0460	homoserine dehydrogenase
FR848_00885	COG0527	aspartate kinase activity
FR848_00890	COG0626	cystathionine gamma-synthase activity
FR848_00900	COG1943	Transposase
FR848_00910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FR848_00915	COG1609	Transcriptional regulator
FR848_00920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR848_00935	COG1575	Belongs to the MenA family. Type 1 subfamily
FR848_00955	COG3678	ATP-independent chaperone mediated protein folding
FR848_00960	COG0745	RESPONSE REGULATOR receiver
FR848_00965	COG2205	protein histidine kinase activity
FR848_00970	COG2258	MOSC domain
FR848_01015	COG1879	ABC-type sugar transport system periplasmic component
FR848_01020	COG1129	ABC transporter
FR848_01025	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_01035	COG1454	alcohol dehydrogenase
FR848_01055	COG1621	beta-fructofuranosidase activity
FR848_01060	COG2211	Major facilitator Superfamily
FR848_01065	COG1609	Transcriptional regulator
FR848_01080	COG0668	transmembrane transport
FR848_01095	COG3121	Chaperone
FR848_01105	COG3539	Fimbrial protein
FR848_01115	COG3188	usher protein
FR848_01120	COG3121	Chaperone
FR848_01130	COG3539	Fimbrial protein
FR848_01145	COG0110	maltose O-acetyltransferase activity
FR848_01150	COG2211	Major facilitator Superfamily
FR848_01195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FR848_01235	COG0205	6-phosphofructokinase activity
FR848_01250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FR848_01260	COG3715	PTS system
FR848_01295	COG0437	4 iron, 4 sulfur cluster binding
FR848_01300	COG2864	formate dehydrogenase
FR848_01315	COG0456	acetyltransferase
FR848_01330	COG1011	Hydrolase
FR848_01340	COG0174	glutamine synthetase
FR848_01345	COG3852	Histidine kinase
FR848_01360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR848_01390	COG0204	Acyl-transferase
FR848_01400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR848_01405	COG3084	Protein conserved in bacteria
FR848_01415	COG1763	Mo-molybdopterin cofactor biosynthetic process
FR848_01435	COG2186	Transcriptional regulator
FR848_01440	COG0477	Major facilitator Superfamily
FR848_01445	COG1609	Transcriptional regulator
FR848_01450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_01455	COG1879	ABC-type sugar transport system periplasmic component
FR848_01460	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_01495	COG1522	sequence-specific DNA binding
FR848_01500	COG0716	FMN binding
FR848_01515	COG3312	ion transport
FR848_01570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR848_01580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FR848_01585	COG0573	inorganic phosphate transmembrane transporter activity
FR848_01590	COG0581	inorganic phosphate transmembrane transporter activity
FR848_01595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR848_01600	COG0704	Plays a role in the regulation of phosphate uptake
FR848_01610	COG2382	esterase
FR848_01615	COG0363	glucosamine-6-phosphate deaminase activity
FR848_01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR848_01630	COG2252	PERMEase
FR848_01635	COG0431	NADPH-dependent FMN reductase
FR848_01640	COG2091	lysine biosynthetic process via aminoadipic acid
FR848_01655	COG0456	acetyltransferase
FR848_01670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FR848_01680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FR848_01690	COG0592	DNA-directed DNA polymerase activity
FR848_01700	COG0187	DNA topoisomerase II activity
FR848_01705	COG0583	DNA-binding transcription factor activity
FR848_01715	COG0561	phosphatase activity
FR848_01720	COG2186	Transcriptional regulator
FR848_01725	COG3734	2-keto-3-deoxy-galactonokinase
FR848_01730	COG0800	Aldolase
FR848_01740	COG2271	Major facilitator Superfamily
FR848_01745	COG0823	Involved in the tonB-independent uptake of proteins
FR848_01750	COG5645	(Lipo)protein
FR848_01770	COG2188	Transcriptional regulator
FR848_01785	COG2149	membrane
FR848_01795	COG0641	radical SAM
FR848_01800	COG3048	D-serine ammonia-lyase activity
FR848_01805	COG2610	gluconate transmembrane transporter activity
FR848_01810	COG0583	DNA-binding transcription factor activity
FR848_01815	COG2814	Major facilitator Superfamily
FR848_01840	COG0028	Belongs to the TPP enzyme family
FR848_01845	COG0440	acetolactate synthase activity
FR848_01850	COG2197	response regulator
FR848_01905	COG2188	Transcriptional regulator
FR848_01930	COG4580	involved in the transport of maltose and maltodextrins
FR848_01935	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR848_01950	COG1609	Transcriptional regulator
FR848_01960	COG5464	transposase or invertase
FR848_01970	COG0697	spore germination
FR848_01985	COG1263	PTS System
FR848_01985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_01995	COG2814	Major facilitator Superfamily
FR848_02000	COG1538	Outer membrane efflux protein
FR848_02005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_02010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_02020	COG1309	transcriptional regulator
FR848_02030	COG0583	DNA-binding transcription factor activity
FR848_02045	COG1464	Belongs to the NlpA lipoprotein family
FR848_02060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FR848_02070	COG1064	alcohol dehydrogenase
FR848_02090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FR848_02120	COG2211	Major facilitator Superfamily
FR848_02125	COG1501	Belongs to the glycosyl hydrolase 31 family
FR848_02130	COG3711	transcriptional antiterminator
FR848_02135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_02135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_02135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_02140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_02145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_02145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_02155	COG0191	fructose-bisphosphate aldolase activity
FR848_02160	COG1940	carbohydrate kinase activity
FR848_02175	COG1486	melibiose metabolic process
FR848_02180	COG1263	PTS System
FR848_02180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_02185	COG2982	Protein involved in outer membrane biogenesis
FR848_02190	COG2233	PERMEase
FR848_02195	COG0786	glutamate:sodium symporter activity
FR848_02210	COG3074	FtsZ-dependent cytokinesis
FR848_02215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FR848_02240	COG3152	Membrane
FR848_02250	COG1494	fructose-1,6-bisphosphatase
FR848_02255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FR848_02260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR848_02265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR848_02290	COG2860	membrane
FR848_02300	COG1561	YicC-like family, N-terminal region
FR848_02310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FR848_02325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FR848_02335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FR848_02360	COG1519	Transferase
FR848_02365	COG1216	Glycosyl transferase, family 2
FR848_02370	COG0438	transferase activity, transferring glycosyl groups
FR848_02380	COG0859	PFAM glycosyl transferase family 9
FR848_02405	COG0859	PFAM glycosyl transferase family 9
FR848_02410	COG0859	PFAM glycosyl transferase family 9
FR848_02420	COG0156	8-amino-7-oxononanoate synthase activity
FR848_02430	COG0463	Glycosyl transferase, family 2
FR848_02435	COG2861	carbohydrate metabolic process
FR848_02440	COG4942	peptidase
FR848_02450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR848_02455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR848_02475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FR848_02485	COG2186	Transcriptional regulator
FR848_02505	COG3722	fumarate hydratase activity
FR848_02525	COG1566	PFAM secretion protein HlyD family protein
FR848_02530	COG0625	glutathione transferase activity
FR848_02540	COG3276	selenocysteine insertion sequence binding
FR848_02550	COG2211	Major facilitator Superfamily
FR848_02555	COG1917	Cupin 2, conserved barrel domain protein
FR848_02555	COG4977	sequence-specific DNA binding
FR848_02560	COG0235	Class ii aldolase
FR848_02565	COG3623	hexulose-6-phosphate isomerase
FR848_02570	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FR848_02575	COG1070	Carbohydrate kinase
FR848_02590	COG2731	YhcH YjgK YiaL family protein
FR848_02605	COG1414	Transcriptional regulator
FR848_02610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_02615	COG3977	Valine--pyruvate aminotransferase
FR848_02620	COG0366	Alpha amylase catalytic
FR848_02625	COG2992	FlgJ-related protein
FR848_02630	COG1609	Transcriptional regulator
FR848_02630	COG2207	Transcriptional regulator
FR848_02635	COG4214	carbohydrate transport
FR848_02640	COG1129	ABC transporter
FR848_02645	COG4213	ABC transporter substrate-binding protein
FR848_02650	COG2115	Belongs to the xylose isomerase family
FR848_02655	COG1070	Carbohydrate kinase
FR848_02660	COG4682	membrane
FR848_02665	COG3274	enterobacterial common antigen metabolic process
FR848_02705	COG1278	Cold shock
FR848_02710	COG2944	sequence-specific DNA binding
FR848_02715	COG2814	Major facilitator Superfamily
FR848_02735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_02745	COG1609	Transcriptional regulator
FR848_02750	COG2885	chlorophyll binding
FR848_02760	COG0243	molybdopterin cofactor binding
FR848_02765	COG0456	acetyltransferase
FR848_02770	COG2818	Glycosylase
FR848_02775	COG5571	outer membrane autotransporter
FR848_02780	COG2223	nitrite transmembrane transporter activity
FR848_02800	COG0747	negative chemotaxis
FR848_02805	COG0601	transmembrane transport
FR848_02810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR848_02815	COG0444	Belongs to the ABC transporter superfamily
FR848_02820	COG4608	Belongs to the ABC transporter superfamily
FR848_02830	COG0489	protein tyrosine kinase activity
FR848_02845	COG0457	Tetratricopeptide repeat
FR848_02875	COG2194	sulfuric ester hydrolase activity
FR848_02910	COG1215	transferase activity, transferring glycosyl groups
FR848_02915	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FR848_02920	COG0457	Tetratricopeptide repeat
FR848_02920	COG3118	belongs to the thioredoxin family
FR848_02930	COG2200	EAL domain
FR848_02930	COG2199	diguanylate cyclase activity
FR848_02940	COG0612	Peptidase, M16
FR848_02955	COG2982	Protein involved in outer membrane biogenesis
FR848_02960	COG0477	Major facilitator Superfamily
FR848_02965	COG1295	ribonuclease BN
FR848_02970	COG0583	DNA-binding transcription factor activity
FR848_02975	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_02980	COG2197	response regulator
FR848_03000	COG1454	alcohol dehydrogenase
FR848_03005	COG0625	glutathione transferase activity
FR848_03010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR848_03015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FR848_03020	COG0671	phosphoesterase, PA-phosphatase related
FR848_03025	COG2205	protein histidine kinase activity
FR848_03030	COG0745	RESPONSE REGULATOR receiver
FR848_03035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR848_03040	COG2183	response to ionizing radiation
FR848_03045	COG1918	ferrous iron import across plasma membrane
FR848_03070	COG1040	competence protein
FR848_03080	COG2610	gluconate transmembrane transporter activity
FR848_03100	COG0589	response to stress
FR848_03110	COG0306	phosphate transporter
FR848_03115	COG2081	HI0933 family
FR848_03120	COG2204	response regulator
FR848_03125	COG3964	amidohydrolase
FR848_03130	COG0471	metal ion transport
FR848_03135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR848_03140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR848_03150	COG2239	Acts as a magnesium transporter
FR848_03170	COG0444	Belongs to the ABC transporter superfamily
FR848_03175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR848_03180	COG0601	transmembrane transport
FR848_03185	COG0747	negative chemotaxis
FR848_03200	COG3479	Phenolic acid decarboxylase
FR848_03240	COG0628	permease
FR848_03245	COG0477	Major facilitator Superfamily
FR848_03255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FR848_03270	COG3714	YhhN family
FR848_03280	COG3776	membrane
FR848_03285	COG0742	ribosomal rna small subunit methyltransferase
FR848_03290	COG0552	protein localization to endoplasmic reticulum
FR848_03295	COG2884	Cell division ATP-binding protein ftsE
FR848_03300	COG2177	Part of the ABC transporter FtsEX involved in
FR848_03315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR848_03325	COG0683	leucine binding
FR848_03340	COG0683	leucine binding
FR848_03345	COG0559	Belongs to the binding-protein-dependent transport system permease family
FR848_03355	COG0411	ABC transporter
FR848_03360	COG0410	ABC transporter
FR848_03365	COG2721	sulfolactate sulfo-lyase activity
FR848_03370	COG2271	Major facilitator Superfamily
FR848_03375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR848_03380	COG1414	Transcriptional regulator
FR848_03385	COG1653	transport
FR848_03405	COG0584	glycerophosphoryl diester phosphodiesterase
FR848_03415	COG0405	Gamma-glutamyltransferase
FR848_03420	COG1247	-acetyltransferase
FR848_03430	COG0673	inositol 2-dehydrogenase activity
FR848_03435	COG1741	Belongs to the pirin family
FR848_03440	COG1609	Transcriptional regulator
FR848_03445	COG3265	gluconokinase activity
FR848_03450	COG2610	gluconate transmembrane transporter activity
FR848_03460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR848_03485	COG0058	SHG alpha-glucan phosphorylase activity
FR848_03490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR848_03505	COG1349	DNA-binding transcription factor activity
FR848_03520	COG0058	SHG alpha-glucan phosphorylase activity
FR848_03525	COG1640	4-alpha-glucanotransferase
FR848_03540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FR848_03545	COG1011	Hydrolase
FR848_03555	COG0494	nUDIX hydrolase
FR848_03560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FR848_03585	COG4796	Type ii and iii secretion system protein
FR848_03600	COG3266	domain, Protein
FR848_03605	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FR848_03610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR848_03635	COG2146	nitrite reductase [NAD(P)H] activity
FR848_03640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR848_03645	COG0402	S-adenosylhomocysteine deaminase activity
FR848_03650	COG0738	Major facilitator superfamily
FR848_03675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR848_03680	COG1289	transmembrane transporter activity
FR848_03690	COG1765	OsmC-like protein
FR848_03695	COG3954	Phosphoribulokinase
FR848_03705	COG0429	hydrolase of the alpha beta-hydrolase fold
FR848_03715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR848_03725	COG0488	(ABC) transporter
FR848_03740	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FR848_03745	COG1047	Peptidyl-prolyl cis-trans
FR848_03755	COG0545	Peptidyl-prolyl cis-trans isomerase
FR848_03760	COG2964	Protein conserved in bacteria
FR848_03800	COG2906	2 iron, 2 sulfur cluster binding
FR848_03815	COG0051	transcription antitermination factor activity, RNA binding
FR848_03825	COG0088	Forms part of the polypeptide exit tunnel
FR848_03850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FR848_03855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FR848_03870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FR848_03905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FR848_03920	COG0201	protein transport
FR848_03935	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FR848_03945	COG0202	RNA polymerase activity
FR848_03950	COG0203	ribosomal protein L17
FR848_03960	COG0789	Transcriptional regulator
FR848_03965	COG3036	rescue of stalled ribosome
FR848_03975	COG0569	domain protein
FR848_03985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FR848_03995	COG0758	DNA mediated transformation
FR848_04005	COG0551	DNA topoisomerase type I activity
FR848_04025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR848_04065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_04070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_04075	COG1309	transcriptional regulator
FR848_04100	COG4145	pantothenate transmembrane transporter activity
FR848_04105	COG3924	membrane
FR848_04110	COG0439	Biotin carboxylase
FR848_04115	COG0511	ligase activity, forming carbon-carbon bonds
FR848_04130	COG0604	alcohol dehydrogenase
FR848_04135	COG2200	EAL domain
FR848_04135	COG2199	diguanylate cyclase activity
FR848_04140	COG1077	Cell shape determining protein MreB Mrl
FR848_04145	COG1792	Involved in formation and maintenance of cell shape
FR848_04150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FR848_04160	COG1530	ribonuclease E activity
FR848_04165	COG3164	Protein of unknown function
FR848_04170	COG0312	modulator of DNA gyrase
FR848_04175	COG1349	DNA-binding transcription factor activity
FR848_04180	COG0583	DNA-binding transcription factor activity
FR848_04195	COG1289	transmembrane transporter activity
FR848_04200	COG2732	(Barnase) inhibitor
FR848_04225	COG1802	Transcriptional regulator
FR848_04235	COG0471	metal ion transport
FR848_04255	COG0511	ligase activity, forming carbon-carbon bonds
FR848_04255	COG5016	pyruvate
FR848_04270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR848_04275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR848_04280	COG3105	Protein conserved in bacteria
FR848_04285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FR848_04300	COG0625	glutathione transferase activity
FR848_04305	COG2969	positive regulation of protein catabolic process
FR848_04335	COG2731	YhcH YjgK YiaL family protein
FR848_04340	COG0493	'glutamate synthase
FR848_04345	COG0070	glutamate synthase
FR848_04345	COG0069	glutamate synthase activity
FR848_04345	COG0067	glutamate synthase
FR848_04355	COG1242	4 iron, 4 sulfur cluster binding
FR848_04360	COG2198	Histidine kinase
FR848_04360	COG5002	protein histidine kinase activity
FR848_04360	COG0784	Response regulator, receiver
FR848_04365	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FR848_04370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR848_04375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_04380	COG1660	Displays ATPase and GTPase activities
FR848_04385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_04390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR848_04395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FR848_04400	COG1137	ATPase activity
FR848_04405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FR848_04410	COG3117	lipopolysaccharide transmembrane transporter activity
FR848_04415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FR848_04425	COG0530	calcium, potassium:sodium antiporter activity
FR848_04430	COG1127	ABC transporter
FR848_04435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FR848_04440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR848_04445	COG2854	intermembrane phospholipid transfer
FR848_04450	COG3113	response to antibiotic
FR848_04455	COG5007	Belongs to the BolA IbaG family
FR848_04465	COG3423	Transcriptional regulator
FR848_04470	COG0142	geranyltranstransferase activity
FR848_04485	COG0697	spore germination
FR848_04495	COG2027	D-alanyl-D-alanine carboxypeptidase
FR848_04500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR848_04505	COG1534	Rna-binding protein
FR848_04515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR848_04520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FR848_04530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR848_04555	COG0195	Participates in both transcription termination and antitermination
FR848_04560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FR848_04595	COG0513	Belongs to the DEAD box helicase family
FR848_04600	COG0814	amino acid
FR848_04605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_04625	COG3153	acetyltransferase
FR848_04630	COG2827	Endonuclease containing a URI domain
FR848_04640	COG0693	protein deglycase activity
FR848_04645	COG0702	epimerase
FR848_04650	COG0701	Predicted permease
FR848_04655	COG2823	Periplasmic or secreted lipoprotein
FR848_04675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FR848_04690	COG2222	sugar isomerase
FR848_04695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FR848_04700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_04705	COG3716	PTS system mannose fructose sorbose family IID component
FR848_04715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_04725	COG1349	DNA-binding transcription factor activity
FR848_04730	COG2721	sulfolactate sulfo-lyase activity
FR848_04735	COG2271	Major facilitator Superfamily
FR848_04745	COG2084	Dehydrogenase
FR848_04750	COG1929	Belongs to the glycerate kinase type-1 family
FR848_04765	COG1741	Belongs to the pirin family
FR848_04770	COG0583	DNA-binding transcription factor activity
FR848_04775	COG3152	Membrane
FR848_04780	COG0435	Glutathione S-transferase
FR848_04785	COG2259	Doxx family
FR848_04795	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FR848_04800	COG4575	ribosome binding
FR848_04805	COG1422	Protein of unknown function (DUF1090)
FR848_04815	COG0586	Pfam SNARE associated Golgi protein
FR848_04820	COG2186	Transcriptional regulator
FR848_04825	COG2271	Major facilitator Superfamily
FR848_04835	COG2721	sulfolactate sulfo-lyase activity
FR848_04855	COG0673	inositol 2-dehydrogenase activity
FR848_04860	COG1451	nucleotide metabolic process
FR848_04865	COG3507	Belongs to the glycosyl hydrolase 43 family
FR848_04875	COG2211	Major facilitator Superfamily
FR848_04885	COG1902	pentaerythritol trinitrate reductase activity
FR848_04885	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR848_04930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FR848_04930	COG3408	Glycogen debranching enzyme
FR848_04940	COG0531	amino acid
FR848_04945	COG0531	amino acid
FR848_04950	COG2731	YhcH YjgK YiaL family protein
FR848_04955	COG3250	beta-galactosidase activity
FR848_04965	COG1609	Transcriptional regulator
FR848_04970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR848_04980	COG1695	Transcriptional regulator
FR848_04985	COG2375	cellular response to nickel ion
FR848_05000	COG1461	Dihydroxyacetone kinase
FR848_05005	COG2376	Dihydroxyacetone kinase
FR848_05040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR848_05045	COG0358	DNA primase activity
FR848_05065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FR848_05070	COG0830	nickel cation binding
FR848_05075	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FR848_05090	COG0831	urea catabolic process
FR848_05105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FR848_05120	COG4991	sh3 domain protein
FR848_05125	COG3025	triphosphatase activity
FR848_05145	COG2960	long-chain fatty acid transporting porin activity
FR848_05155	COG3539	Fimbrial protein
FR848_05160	COG3121	Chaperone
FR848_05165	COG3188	usher protein
FR848_05170	COG3539	Fimbrial protein
FR848_05180	COG3384	dioxygenase
FR848_05185	COG0754	glutathionylspermidine amidase activity
FR848_05200	COG0494	nUDIX hydrolase
FR848_05205	COG3151	Protein conserved in bacteria
FR848_05210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FR848_05215	COG3150	esterase
FR848_05220	COG0187	DNA topoisomerase II activity
FR848_05225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FR848_05230	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR848_05235	COG0642	Histidine kinase
FR848_05240	COG0745	RESPONSE REGULATOR receiver
FR848_05245	COG3111	PFAM Bacterial OB fold (BOF) protein
FR848_05250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FR848_05260	COG0204	Acyl-transferase
FR848_05265	COG2132	Multicopper oxidase
FR848_05270	COG1032	radical SAM domain protein
FR848_05305	COG0640	Transcriptional regulator
FR848_05310	COG1902	pentaerythritol trinitrate reductase activity
FR848_05325	COG0697	spore germination
FR848_05380	COG3344	reverse transcriptase
FR848_05430	COG0604	alcohol dehydrogenase
FR848_05465	COG1032	radical SAM domain protein
FR848_05480	COG1979	alcohol dehydrogenase
FR848_05485	COG2207	Transcriptional regulator
FR848_05490	COG0586	Pfam SNARE associated Golgi protein
FR848_05500	COG0811	peptide transport
FR848_05505	COG0848	biopolymer transport protein
FR848_05525	COG0625	glutathione transferase activity
FR848_05535	COG0754	glutathionylspermidine amidase activity
FR848_05540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR848_05550	COG2365	Tyrosine phosphatase family
FR848_05570	COG0626	cystathionine gamma-synthase activity
FR848_05585	COG0471	metal ion transport
FR848_05600	COG1811	Na channel or pump
FR848_05605	COG1982	Orn Lys Arg decarboxylase major
FR848_05610	COG2211	Major facilitator Superfamily
FR848_05625	COG1194	a g-specific adenine glycosylase
FR848_05635	COG3171	Protein conserved in bacteria
FR848_05650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR848_05655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR848_05660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR848_05675	COG0762	integral membrane protein
FR848_05680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FR848_05685	COG2805	Type II/IV secretion system protein
FR848_05690	COG2197	response regulator
FR848_05705	COG0189	ligase activity
FR848_05710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR848_05715	COG2356	endonuclease I
FR848_05725	COG2814	Major facilitator Superfamily
FR848_05740	COG1166	arginine decarboxylase activity
FR848_05750	COG0501	Belongs to the peptidase M48B family
FR848_05755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR848_05760	COG1122	ATPase activity
FR848_05795	COG0191	fructose-bisphosphate aldolase activity
FR848_05800	COG0668	transmembrane transport
FR848_05810	COG2968	Membrane
FR848_05815	COG0583	DNA-binding transcription factor activity
FR848_05820	COG0427	acetyl-CoA hydrolase
FR848_05825	COG1024	Enoyl-CoA hydratase
FR848_05830	COG1703	isobutyryl-CoA mutase activity
FR848_05835	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FR848_05835	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FR848_05850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR848_05855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FR848_05875	COG0006	proline dipeptidase activity
FR848_05880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR848_05885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR848_05905	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_05910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR848_05915	COG2723	6-phospho-beta-galactosidase activity
FR848_05920	COG1737	Transcriptional regulator
FR848_05930	COG1272	protein, Hemolysin III
FR848_05945	COG3716	PTS system mannose fructose sorbose family IID component
FR848_05950	COG3715	PTS system
FR848_05955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_05955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_05975	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FR848_05985	COG0716	FMN binding
FR848_05990	COG4974	Belongs to the 'phage' integrase family
FR848_06000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FR848_06020	COG1811	Na channel or pump
FR848_06030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FR848_06035	COG0583	DNA-binding transcription factor activity
FR848_06040	COG4942	peptidase
FR848_06050	COG0582	viral genome integration into host DNA
FR848_06060	COG1309	transcriptional regulator
FR848_06070	COG1064	alcohol dehydrogenase
FR848_06085	COG4221	oxidoreductase activity
FR848_06120	COG0702	epimerase
FR848_06130	COG0667	Aldo Keto reductase
FR848_06135	COG0656	L-ascorbic acid biosynthetic process
FR848_06165	COG5002	protein histidine kinase activity
FR848_06175	COG0667	Aldo Keto reductase
FR848_06185	COG0778	Nitroreductase
FR848_06190	COG2814	Major facilitator Superfamily
FR848_06205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FR848_06210	COG1393	Belongs to the ArsC family
FR848_06215	COG2814	Major facilitator Superfamily
FR848_06230	COG3835	regulator
FR848_06235	COG1929	Belongs to the glycerate kinase type-1 family
FR848_06280	COG0738	Major facilitator superfamily
FR848_06285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_06290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR848_06295	COG1349	DNA-binding transcription factor activity
FR848_06325	COG3104	oligopeptide transport
FR848_06335	COG2909	trisaccharide binding
FR848_06340	COG1538	Outer membrane efflux protein
FR848_06345	COG1289	transmembrane transporter activity
FR848_06360	COG3592	Divergent 4Fe-4S mono-cluster
FR848_06365	COG2388	GCN5-related N-acetyl-transferase
FR848_06375	COG1522	sequence-specific DNA binding
FR848_06380	COG1846	Transcriptional regulator
FR848_06385	COG0697	spore germination
FR848_06405	COG0640	Transcriptional regulator
FR848_06450	COG0667	Aldo Keto reductase
FR848_06455	COG0814	amino acid
FR848_06470	COG0183	Belongs to the thiolase family
FR848_06475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FR848_06480	COG0823	Involved in the tonB-independent uptake of proteins
FR848_06485	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_06490	COG2814	Major facilitator Superfamily
FR848_06515	COG0823	Involved in the tonB-independent uptake of proteins
FR848_06525	COG3842	ATPase activity
FR848_06530	COG0395	ABC-type sugar transport system, permease component
FR848_06535	COG1175	transmembrane transport
FR848_06545	COG1794	racemase activity, acting on amino acids and derivatives
FR848_06555	COG3188	usher protein
FR848_06560	COG3121	Chaperone
FR848_06570	COG3539	Fimbrial protein
FR848_06575	COG0583	DNA-binding transcription factor activity
FR848_06580	COG0019	diaminopimelate decarboxylase activity
FR848_06585	COG1609	Transcriptional regulator
FR848_06590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_06595	COG2723	6-phospho-beta-galactosidase activity
FR848_06600	COG2186	Transcriptional regulator
FR848_06610	COG1609	Transcriptional regulator
FR848_06625	COG0667	Aldo Keto reductase
FR848_06635	COG0861	Integral membrane protein TerC family
FR848_06675	COG2165	general secretion pathway protein
FR848_06680	COG4795	General secretion pathway protein
FR848_06690	COG4967	type IV pilus modification protein PilV
FR848_06695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FR848_06700	COG1025	Belongs to the peptidase M16 family
FR848_06705	COG1074	ATP-dependent DNA helicase activity
FR848_06710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR848_06715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FR848_06715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR848_06720	COG0860	N-Acetylmuramoyl-L-alanine amidase
FR848_06725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FR848_06745	COG4810	utilization protein
FR848_06755	COG4656	Part of a membrane complex involved in electron transport
FR848_06760	COG1012	belongs to the aldehyde dehydrogenase family
FR848_06760	COG1454	alcohol dehydrogenase
FR848_06790	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_06795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_06830	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_06865	COG2241	protein methyltransferase activity
FR848_06875	COG2875	Belongs to the precorrin methyltransferase family
FR848_06955	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FR848_06960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FR848_06965	COG2166	iron-sulfur cluster assembly
FR848_06970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR848_06980	COG0583	DNA-binding transcription factor activity
FR848_06985	COG2363	Small membrane protein
FR848_06995	COG1349	DNA-binding transcription factor activity
FR848_07015	COG0738	Major facilitator superfamily
FR848_07020	COG0235	Class ii aldolase
FR848_07035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_07050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR848_07055	COG1760	l-serine dehydratase
FR848_07060	COG0814	amino acid
FR848_07065	COG1611	Belongs to the LOG family
FR848_07080	COG3098	single-species biofilm formation
FR848_07085	COG0564	pseudouridine synthase activity
FR848_07090	COG0716	FMN binding
FR848_07100	COG2271	Major facilitator Superfamily
FR848_07105	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_07110	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_07115	COG1929	Belongs to the glycerate kinase type-1 family
FR848_07120	COG3437	response regulator, receiver
FR848_07120	COG2205	protein histidine kinase activity
FR848_07120	COG4999	Histidine kinase
FR848_07120	COG3850	Histidine kinase
FR848_07130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR848_07135	COG3956	TIGRFAM MazG family protein
FR848_07155	COG0602	queuosine metabolic process
FR848_07160	COG0720	synthase
FR848_07195	COG1104	cysteine desulfurase activity
FR848_07200	COG0697	spore germination
FR848_07215	COG2234	aminopeptidase activity
FR848_07275	COG4942	peptidase
FR848_07275	COG1388	LysM domain
FR848_07280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR848_07290	COG0477	Major facilitator Superfamily
FR848_07310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FR848_07335	COG3539	Fimbrial protein
FR848_07345	COG3188	usher protein
FR848_07350	COG3121	Chaperone
FR848_07360	COG3539	Fimbrial protein
FR848_07390	COG1132	(ABC) transporter
FR848_07395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_07405	COG1538	Outer membrane efflux protein
FR848_07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR848_07455	COG1454	alcohol dehydrogenase
FR848_07460	COG2186	Transcriptional regulator
FR848_07465	COG1063	alcohol dehydrogenase
FR848_07470	COG2271	Major facilitator Superfamily
FR848_07475	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_07485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FR848_07490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_07495	COG4558	Periplasmic binding protein
FR848_07500	COG3720	iron ion transport
FR848_07520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR848_07525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR848_07530	COG1121	(ABC) transporter
FR848_07540	COG1609	Transcriptional regulator
FR848_07545	COG1940	carbohydrate kinase activity
FR848_07550	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR848_07555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_07560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_07565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_07580	COG2723	6-phospho-beta-galactosidase activity
FR848_07585	COG0657	acetylesterase activity
FR848_07585	COG2755	lipolytic protein G-D-S-L family
FR848_07595	COG0309	Hydrogenase expression formation protein (HypE)
FR848_07600	COG0409	Hydrogenase expression formation protein
FR848_07605	COG0298	carbon dioxide binding
FR848_07610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FR848_07625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_07630	COG0651	ATP synthesis coupled electron transport
FR848_07635	COG0650	Formate hydrogenlyase subunit 4
FR848_07640	COG3261	NADH dehydrogenase
FR848_07640	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FR848_07645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FR848_07650	COG3260	NADH ubiquinone oxidoreductase 20
FR848_07660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FR848_07670	COG2723	6-phospho-beta-galactosidase activity
FR848_07675	COG1263	PTS System
FR848_07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_07685	COG1609	Transcriptional regulator
FR848_07690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_07695	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FR848_07700	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FR848_07730	COG1349	DNA-binding transcription factor activity
FR848_07735	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_07740	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_07750	COG3732	PTS system glucitol sorbitol-specific
FR848_07755	COG3730	PTS system glucitol sorbitol-specific
FR848_07760	COG2951	lytic endotransglycosylase activity
FR848_07770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR848_07775	COG0803	Belongs to the bacterial solute-binding protein 9 family
FR848_07785	COG1546	Belongs to the CinA family
FR848_07835	COG2823	Periplasmic or secreted lipoprotein
FR848_07840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR848_07845	COG1238	metal cluster binding
FR848_07865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR848_07870	COG2814	Major facilitator Superfamily
FR848_07875	COG1566	PFAM secretion protein HlyD family protein
FR848_07880	COG1846	Transcriptional regulator
FR848_07890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FR848_07895	COG2113	Glycine betaine
FR848_07900	COG4176	ABC-type proline glycine betaine transport system permease component
FR848_07910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR848_07915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR848_07925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR848_07930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_07940	COG4575	ribosome binding
FR848_07960	COG2916	Histone family protein nucleoid-structuring protein H-NS
FR848_07970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR848_07975	COG0640	Transcriptional regulator
FR848_07980	COG0671	phosphoesterase, PA-phosphatase related
FR848_07985	COG3284	Transcriptional regulator
FR848_07990	COG1012	belongs to the aldehyde dehydrogenase family
FR848_08010	COG3188	usher protein
FR848_08035	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_08040	COG2814	Major facilitator Superfamily
FR848_08045	COG1858	cytochrome C peroxidase
FR848_08060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR848_08065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR848_08075	COG1138	Cytochrome C-type biogenesis protein
FR848_08080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR848_08085	COG3088	subunit of a heme lyase
FR848_08085	COG4235	cytochrome complex assembly
FR848_08095	COG0235	Class ii aldolase
FR848_08100	COG1126	abc transporter atp-binding protein
FR848_08105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_08145	COG2197	response regulator
FR848_08150	COG0784	Response regulator, receiver
FR848_08150	COG2205	protein histidine kinase activity
FR848_08150	COG2198	Histidine kinase
FR848_08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_08165	COG3121	Chaperone
FR848_08205	COG0582	viral genome integration into host DNA
FR848_08295	COG0484	heat shock protein binding
FR848_08355	COG1802	Transcriptional regulator
FR848_08355	COG4626	Terminase
FR848_08360	COG4695	Portal protein
FR848_08365	COG0740	serine-type endopeptidase activity
FR848_08500	COG2867	negative regulation of translational initiation
FR848_08515	COG0497	DNA recombination
FR848_08530	COG4536	flavin adenine dinucleotide binding
FR848_08535	COG4137	Cytochrome C assembly protein
FR848_08540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR848_08575	COG2885	chlorophyll binding
FR848_08580	COG2199	diguanylate cyclase activity
FR848_08590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR848_08595	COG1605	Chorismate mutase
FR848_08595	COG0287	Prephenate dehydrogenase
FR848_08605	COG1605	Chorismate mutase
FR848_08605	COG0077	Prephenate dehydratase
FR848_08615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR848_08620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR848_08625	COG0564	pseudouridine synthase activity
FR848_08635	COG0542	response to heat
FR848_08665	COG0477	Major facilitator Superfamily
FR848_08670	COG5544	Lipoprotein
FR848_08675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR848_08690	COG3118	belongs to the thioredoxin family
FR848_08695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR848_08700	COG3385	transposase activity
FR848_08715	COG0513	Belongs to the DEAD box helicase family
FR848_08725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FR848_08740	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FR848_08745	COG3026	antisigma factor binding
FR848_08750	COG3086	response to oxidative stress
FR848_08760	COG0681	Belongs to the peptidase S26 family
FR848_08780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FR848_08790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_08795	COG1737	Transcriptional regulator
FR848_08800	COG0560	Phosphoserine phosphatase
FR848_08805	COG0590	tRNA wobble adenosine to inosine editing
FR848_08820	COG0047	phosphoribosylformylglycinamidine synthase activity
FR848_08820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FR848_08825	COG2205	protein histidine kinase activity
FR848_08830	COG3170	Tfp pilus assembly protein FimV
FR848_08835	COG2204	response regulator
FR848_08840	COG0347	Belongs to the P(II) protein family
FR848_08845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR848_08845	COG1017	nitric oxide dioxygenase activity
FR848_08855	COG2259	Doxx family
FR848_08860	COG1940	carbohydrate kinase activity
FR848_08865	COG0457	Tetratricopeptide repeat
FR848_08870	COG2814	Major facilitator Superfamily
FR848_08870	COG0477	Major facilitator Superfamily
FR848_08875	COG2017	converts alpha-aldose to the beta-anomer
FR848_08880	COG2814	Major facilitator Superfamily
FR848_08885	COG3711	transcriptional antiterminator
FR848_08890	COG3683	transport system, periplasmic component
FR848_08895	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FR848_08920	COG0822	iron-sulfur transferase activity
FR848_08940	COG0633	Ferredoxin
FR848_08945	COG2975	iron-sulfur cluster assembly
FR848_08960	COG2897	thiosulfate sulfurtransferase activity
FR848_08965	COG1473	amidohydrolase
FR848_08975	COG2373	Large extracellular alpha-helical protein
FR848_08980	COG4953	penicillin-binding protein 1C
FR848_09010	COG2976	Protein conserved in bacteria
FR848_09035	COG1645	bacterial-type flagellum-dependent swarming motility
FR848_09050	COG1570	exodeoxyribonuclease VII activity
FR848_09055	COG0516	GMP reductase activity
FR848_09055	COG0517	IMP dehydrogenase activity
FR848_09060	COG0519	Catalyzes the synthesis of GMP from XMP
FR848_09060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR848_09070	COG0583	DNA-binding transcription factor activity
FR848_09080	COG2200	EAL domain
FR848_09085	COG0248	Ppx GppA phosphatase
FR848_09105	COG2211	Major facilitator Superfamily
FR848_09115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FR848_09130	COG2723	6-phospho-beta-galactosidase activity
FR848_09135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FR848_09140	COG2233	PERMEase
FR848_09150	COG1393	Belongs to the ArsC family
FR848_09155	COG4783	chaperone-mediated protein folding
FR848_09160	COG0628	permease
FR848_09165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR848_09170	COG2716	regulation of RNA biosynthetic process
FR848_09180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FR848_09190	COG2321	neutral zinc metallopeptidase
FR848_09200	COG0400	carboxylic ester hydrolase activity
FR848_09225	COG1393	Belongs to the ArsC family
FR848_09235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_09240	COG0493	'glutamate synthase
FR848_09240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_09250	COG5342	invasion associated locus B
FR848_09255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR848_09265	COG4810	utilization protein
FR848_09270	COG4917	ethanolamine utilization protein
FR848_09275	COG4766	ethanolamine catabolic process
FR848_09305	COG4820	ethanolamine utilization protein (EutJ)
FR848_09340	COG4816	utilization protein
FR848_09350	COG2207	Transcriptional regulator
FR848_09360	COG0860	N-Acetylmuramoyl-L-alanine amidase
FR848_09380	COG2837	iron assimilation
FR848_09385	COG4150	thiosulfate binding
FR848_09390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FR848_09395	COG4208	sulfate ABC transporter
FR848_09400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FR848_09410	COG4319	ketosteroid isomerase
FR848_09435	COG2190	(PTS) system
FR848_09455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR848_09475	COG3530	Putative quorum-sensing-regulated virulence factor
FR848_09480	COG0385	Bile acid
FR848_09485	COG0583	DNA-binding transcription factor activity
FR848_09490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FR848_09495	COG2211	Major facilitator Superfamily
FR848_09500	COG0583	DNA-binding transcription factor activity
FR848_09530	COG3415	Transposase
FR848_09535	COG3415	Transposase
FR848_09550	COG2200	EAL domain
FR848_09550	COG2199	diguanylate cyclase activity
FR848_09555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR848_09570	COG0667	Aldo Keto reductase
FR848_09575	COG3961	Belongs to the TPP enzyme family
FR848_09590	COG3279	Response regulator of the LytR AlgR family
FR848_09595	COG3275	phosphorelay sensor kinase activity
FR848_09600	COG0436	Aminotransferase
FR848_09610	COG2807	transmembrane transport
FR848_09615	COG0583	DNA-binding transcription factor activity
FR848_09640	COG2116	formate transmembrane transporter activity
FR848_09655	COG3691	Protein conserved in bacteria
FR848_09670	COG2062	phosphohistidine phosphatase, SixA
FR848_09680	COG2890	protein-(glutamine-N5) methyltransferase activity
FR848_09695	COG0730	response to heat
FR848_09700	COG3101	peptidyl-lysine hydroxylation
FR848_09715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR848_09735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR848_09745	COG0586	Pfam SNARE associated Golgi protein
FR848_09755	COG0285	dihydrofolate synthase activity
FR848_09760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FR848_09765	COG1286	toxin biosynthetic process
FR848_09770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FR848_09775	COG0163	prenyltransferase activity
FR848_09790	COG4215	(ABC) transporter
FR848_09795	COG4160	amino acid transport
FR848_09800	COG4598	ABC transporter
FR848_09820	COG1090	epimerase
FR848_09825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FR848_09830	COG0625	glutathione transferase activity
FR848_09835	COG0625	glutathione transferase activity
FR848_09840	COG0622	Phosphoesterase
FR848_09845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FR848_09850	COG1609	Transcriptional regulator
FR848_09855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_09865	COG3037	sugar-specific permease SgaT UlaA
FR848_09870	COG3959	Transketolase, thiamine diphosphate binding domain
FR848_09875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FR848_09885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR848_09900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR848_09905	COG0471	metal ion transport
FR848_09905	COG0490	domain, Protein
FR848_09915	COG0436	Aminotransferase
FR848_09920	COG0583	DNA-binding transcription factor activity
FR848_09945	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FR848_09955	COG1034	ATP synthesis coupled electron transport
FR848_09970	COG0839	Belongs to the complex I subunit 6 family
FR848_09975	COG0713	ATP synthesis coupled electron transport
FR848_09980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FR848_09985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FR848_09995	COG0582	viral genome integration into host DNA
FR848_10005	COG3121	Chaperone
FR848_10025	COG0582	viral genome integration into host DNA
FR848_10035	COG2153	protein acetylation
FR848_10040	COG1169	isochorismate synthase
FR848_10070	COG3647	Membrane
FR848_10095	COG0642	Histidine kinase
FR848_10100	COG0494	nUDIX hydrolase
FR848_10125	COG1414	Transcriptional regulator
FR848_10135	COG2271	Major facilitator Superfamily
FR848_10145	COG0247	lactate metabolic process
FR848_10155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR848_10160	COG2271	Major facilitator Superfamily
FR848_10165	COG0584	glycerophosphoryl diester phosphodiesterase
FR848_10170	COG0583	DNA-binding transcription factor activity
FR848_10175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FR848_10180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR848_10205	COG0784	Response regulator, receiver
FR848_10205	COG2205	protein histidine kinase activity
FR848_10215	COG2198	Histidine kinase
FR848_10215	COG0642	Histidine kinase
FR848_10235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR848_10235	COG2169	Transcriptional regulator
FR848_10240	COG3145	DNA-N1-methyladenine dioxygenase activity
FR848_10245	COG4615	Cyclic peptide transporter
FR848_10250	COG2239	Acts as a magnesium transporter
FR848_10255	COG0659	secondary active sulfate transmembrane transporter activity
FR848_10270	COG0628	permease
FR848_10330	COG1388	LysM domain
FR848_10330	COG3858	chitin binding
FR848_10415	COG1349	DNA-binding transcription factor activity
FR848_10420	COG0494	nUDIX hydrolase
FR848_10430	COG1061	Type III restriction enzyme res subunit
FR848_10435	COG1187	pseudouridine synthase activity
FR848_10440	COG2814	Major facilitator Superfamily
FR848_10450	COG4172	Belongs to the ABC transporter superfamily
FR848_10455	COG4239	(ABC) transporter, permease
FR848_10460	COG4174	ABC transporter (Permease)
FR848_10465	COG4166	transmembrane transport
FR848_10470	COG2200	EAL domain
FR848_10475	COG0791	NLP P60 protein
FR848_10480	COG0671	phosphoesterase, PA-phosphatase related
FR848_10485	COG0523	cobalamin synthesis protein
FR848_10490	COG0246	Mannitol dehydrogenase
FR848_10495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FR848_10505	COG2814	Major facilitator Superfamily
FR848_10510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_10510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_10515	COG1105	Belongs to the carbohydrate kinase PfkB family
FR848_10520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_10520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FR848_10520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_10530	COG2313	pseudouridylate synthase activity
FR848_10535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR848_10540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_10540	COG1522	sequence-specific DNA binding
FR848_10550	COG2855	membrane
FR848_10555	COG0583	DNA-binding transcription factor activity
FR848_10560	COG0833	amino acid
FR848_10565	COG4771	TonB-dependent receptor
FR848_10580	COG2311	Membrane
FR848_10595	COG1129	ABC transporter
FR848_10605	COG2949	membrane
FR848_10615	COG1346	cytolysis
FR848_10625	COG0583	DNA-binding transcription factor activity
FR848_10630	COG2271	Major facilitator Superfamily
FR848_10645	COG0625	glutathione transferase activity
FR848_10650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR848_10655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR848_10670	COG2723	6-phospho-beta-galactosidase activity
FR848_10675	COG2226	methyltransferase
FR848_10680	COG1538	Outer membrane efflux protein
FR848_10685	COG0586	Pfam SNARE associated Golgi protein
FR848_10695	COG1686	Belongs to the peptidase S11 family
FR848_10705	COG0277	FAD linked oxidase domain protein
FR848_10710	COG1472	Belongs to the glycosyl hydrolase 3 family
FR848_10715	COG1732	Glycine betaine
FR848_10720	COG1174	glycine betaine transport
FR848_10725	COG1125	glycine betaine transport
FR848_10730	COG1174	glycine betaine transport
FR848_10740	COG0789	Transcriptional regulator
FR848_10745	COG3275	phosphorelay sensor kinase activity
FR848_10755	COG4807	Protein conserved in bacteria
FR848_10760	COG4808	Protein conserved in bacteria
FR848_10780	COG5455	response to cobalt ion
FR848_10785	COG0583	DNA-binding transcription factor activity
FR848_10790	COG2252	PERMEase
FR848_10800	COG0583	DNA-binding transcription factor activity
FR848_10810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR848_10900	COG0351	phosphomethylpyrimidine kinase
FR848_10905	COG1830	Aldolase
FR848_10935	COG1070	Carbohydrate kinase
FR848_10945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR848_10950	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_10955	COG0747	negative chemotaxis
FR848_10960	COG0601	transmembrane transport
FR848_10970	COG0444	Belongs to the ABC transporter superfamily
FR848_10975	COG4608	Belongs to the ABC transporter superfamily
FR848_11000	COG0745	RESPONSE REGULATOR receiver
FR848_11005	COG2205	protein histidine kinase activity
FR848_11035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_11040	COG4215	(ABC) transporter
FR848_11050	COG1522	sequence-specific DNA binding
FR848_11060	COG2267	carboxylic ester hydrolase activity
FR848_11075	COG0601	transmembrane transport
FR848_11080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR848_11085	COG0444	Belongs to the ABC transporter superfamily
FR848_11090	COG4608	Belongs to the ABC transporter superfamily
FR848_11100	COG1301	dicarboxylic acid transport
FR848_11120	COG2205	protein histidine kinase activity
FR848_11125	COG0372	Belongs to the citrate synthase family
FR848_11130	COG0443	Heat shock 70 kDa protein
FR848_11135	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FR848_11150	COG2982	Protein involved in outer membrane biogenesis
FR848_11155	COG1253	flavin adenine dinucleotide binding
FR848_11305	COG1215	transferase activity, transferring glycosyl groups
FR848_11315	COG0107	imidazoleglycerol-phosphate synthase activity
FR848_11325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FR848_11340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR848_11355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR848_11360	COG0583	DNA-binding transcription factor activity
FR848_11370	COG0531	amino acid
FR848_11385	COG3604	Transcriptional regulator
FR848_11390	COG2205	protein histidine kinase activity
FR848_11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_11405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_11475	COG0640	Transcriptional regulator
FR848_11480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR848_11490	COG3335	DDE superfamily endonuclease
FR848_11515	COG1289	transmembrane transporter activity
FR848_11535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FR848_11545	COG2814	Major facilitator Superfamily
FR848_11550	COG0673	inositol 2-dehydrogenase activity
FR848_11555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_11555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_11560	COG1082	Xylose isomerase domain protein TIM barrel
FR848_11570	COG1942	4-Oxalocrotonate Tautomerase
FR848_11575	COG0583	DNA-binding transcription factor activity
FR848_11580	COG0095	Lipoate-protein ligase
FR848_11585	COG0477	Major facilitator Superfamily
FR848_11595	COG5001	Diguanylate cyclase
FR848_11595	COG3300	MHYT domain
FR848_11600	COG3615	Tellurite resistance protein tehB
FR848_11610	COG2188	Transcriptional regulator
FR848_11615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_11615	COG1263	PTS System
FR848_11630	COG3539	Fimbrial protein
FR848_11635	COG3539	Fimbrial protein
FR848_11640	COG3539	Fimbrial protein
FR848_11645	COG3188	usher protein
FR848_11650	COG3121	Chaperone
FR848_11655	COG3539	Fimbrial protein
FR848_11695	COG1376	ErfK ybiS ycfS ynhG family protein
FR848_11710	COG0667	Aldo Keto reductase
FR848_11715	COG0583	DNA-binding transcription factor activity
FR848_11870	COG0582	viral genome integration into host DNA
FR848_11880	COG0534	Mate efflux family protein
FR848_11895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FR848_11925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_11935	COG0589	response to stress
FR848_11945	COG2819	hydrolase of the alpha beta superfamily
FR848_11965	COG0251	oxidation-reduction process
FR848_11995	COG0463	Glycosyl transferase, family 2
FR848_12005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR848_12015	COG1418	mRNA catabolic process
FR848_12020	COG0270	DNA (cytosine-5-)-methyltransferase activity
FR848_12025	COG3727	T/G mismatch-specific endonuclease activity
FR848_12030	COG0697	spore germination
FR848_12035	COG2354	Protein conserved in bacteria
FR848_12040	COG5475	Uncharacterized small protein (DUF2158)
FR848_12070	COG0366	Alpha amylase catalytic
FR848_12095	COG2197	response regulator
FR848_12105	COG2197	response regulator
FR848_12115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR848_12135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR848_12140	COG3012	SEC-C Motif Domain Protein
FR848_12140	COG3318	Belongs to the UPF0149 family
FR848_12145	COG0814	amino acid
FR848_12155	COG1528	Iron-storage protein
FR848_12165	COG0477	Major facilitator Superfamily
FR848_12185	COG1528	Iron-storage protein
FR848_12195	COG1879	ABC-type sugar transport system periplasmic component
FR848_12205	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_12235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FR848_12245	COG3102	Protein conserved in bacteria
FR848_12265	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FR848_12270	COG1801	Protein of unknown function DUF72
FR848_12275	COG1335	isochorismatase
FR848_12285	COG0494	nUDIX hydrolase
FR848_12290	COG0217	transcriptional regulatory protein
FR848_12310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR848_12315	COG1121	(ABC) transporter
FR848_12320	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FR848_12325	COG0739	heme binding
FR848_12330	COG1560	Kdo2-lipid A biosynthetic process
FR848_12340	COG0281	malic enzyme
FR848_12345	COG0679	Auxin Efflux Carrier
FR848_12350	COG3493	citrate carrier protein
FR848_12360	COG1737	Transcriptional regulator
FR848_12365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FR848_12370	COG0129	dihydroxy-acid dehydratase activity
FR848_12375	COG0800	Aldolase
FR848_12385	COG3141	response to X-ray
FR848_12390	COG2979	Protein of unknown function (DUF533)
FR848_12395	COG1770	oligopeptidase
FR848_12400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR848_12410	COG2372	response to copper ion
FR848_12415	COG1276	copper resistance
FR848_12455	COG2990	Protein conserved in bacteria
FR848_12480	COG3008	intermembrane lipid transfer
FR848_12485	COG2995	paraquat-inducible protein a
FR848_12490	COG1956	GAF domain-containing protein
FR848_12510	COG2814	Major facilitator Superfamily
FR848_12515	COG1414	Transcriptional regulator
FR848_12540	COG1278	Cold shock
FR848_12545	COG0768	penicillin binding
FR848_12550	COG2226	methyltransferase
FR848_12565	COG3716	PTS system mannose fructose sorbose family IID component
FR848_12570	COG3715	PTS system
FR848_12575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_12575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_12580	COG1253	flavin adenine dinucleotide binding
FR848_12585	COG2200	EAL domain
FR848_12590	COG1760	l-serine dehydratase
FR848_12620	COG1653	transport
FR848_12630	COG0395	ABC-type sugar transport system, permease component
FR848_12635	COG3842	ATPase activity
FR848_12645	COG0251	oxidation-reduction process
FR848_12650	COG1199	ATP-dependent helicase activity
FR848_12655	COG1214	PFAM Peptidase M22, glycoprotease
FR848_12660	COG3065	identical protein binding
FR848_12665	COG0318	PFAM AMP-dependent synthetase and ligase
FR848_12670	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FR848_12680	COG2894	cell division
FR848_12695	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR848_12725	COG1943	Transposase
FR848_12730	COG2719	SpoVR family
FR848_12750	COG1619	proteins homologs of microcin C7 resistance protein MccF
FR848_12765	COG2211	Major facilitator Superfamily
FR848_12785	COG2308	Evidence 4 Homologs of previously reported genes of
FR848_12810	COG2814	Major facilitator Superfamily
FR848_12835	COG1174	glycine betaine transport
FR848_12850	COG0564	pseudouridine synthase activity
FR848_12855	COG0583	DNA-binding transcription factor activity
FR848_12875	COG2351	hydroxyisourate hydrolase activity
FR848_12880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_12880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_12885	COG2814	Major facilitator Superfamily
FR848_12900	COG2068	MobA-Related Protein
FR848_12910	COG2233	PERMEase
FR848_12920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_12925	COG0402	S-adenosylhomocysteine deaminase activity
FR848_12930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR848_12930	COG0493	'glutamate synthase
FR848_12935	COG3608	succinylglutamate desuccinylase aspartoacylase
FR848_12935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FR848_12940	COG0549	Belongs to the carbamate kinase family
FR848_12950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR848_12955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR848_12960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FR848_12980	COG0582	viral genome integration into host DNA
FR848_12985	COG0012	GTP binding
FR848_13005	COG0659	secondary active sulfate transmembrane transporter activity
FR848_13010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR848_13035	COG2890	protein-(glutamine-N5) methyltransferase activity
FR848_13040	COG3094	Invasion gene expression up-regulator, SirB
FR848_13045	COG2912	Transglutaminase-like superfamily
FR848_13055	COG0387	Pfam Sodium calcium exchanger
FR848_13060	COG4572	Cation transport regulator
FR848_13065	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FR848_13075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FR848_13080	COG3707	response regulator
FR848_13085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR848_13095	COG1116	anion transmembrane transporter activity
FR848_13100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR848_13100	COG2146	nitrite reductase [NAD(P)H] activity
FR848_13105	COG0243	molybdopterin cofactor binding
FR848_13110	COG4932	domain protein
FR848_13115	COG2197	response regulator
FR848_13120	COG3850	Histidine kinase
FR848_13125	COG2223	nitrite transmembrane transporter activity
FR848_13130	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FR848_13135	COG1140	nitrate reductase beta subunit
FR848_13140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FR848_13145	COG2181	nitrate reductase activity
FR848_13175	COG0788	formyltetrahydrofolate deformylase activity
FR848_13185	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR848_13190	COG0745	RESPONSE REGULATOR receiver
FR848_13195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FR848_13200	COG2916	Histone family protein nucleoid-structuring protein H-NS
FR848_13215	COG1012	belongs to the aldehyde dehydrogenase family
FR848_13215	COG1454	alcohol dehydrogenase
FR848_13220	COG2095	MarC family integral membrane protein
FR848_13235	COG0601	transmembrane transport
FR848_13240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR848_13245	COG0444	Belongs to the ABC transporter superfamily
FR848_13255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR848_13275	COG1902	pentaerythritol trinitrate reductase activity
FR848_13280	COG2350	Protein conserved in bacteria
FR848_13300	COG1105	Belongs to the carbohydrate kinase PfkB family
FR848_13305	COG3137	Salt-induced outer membrane protein
FR848_13335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FR848_13355	COG0072	phenylalanine-tRNA ligase activity
FR848_13355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR848_13375	COG0386	Belongs to the glutathione peroxidase family
FR848_13385	COG0791	NLP P60 protein
FR848_13395	COG4256	Hemin uptake protein
FR848_13400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR848_13410	COG0574	Belongs to the PEP-utilizing enzyme family
FR848_13410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR848_13420	COG0628	permease
FR848_13425	COG0247	lactate metabolic process
FR848_13425	COG0277	FAD linked oxidase domain protein
FR848_13430	COG2050	protein possibly involved in aromatic compounds catabolism
FR848_13435	COG2261	transglycosylase associated protein
FR848_13440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR848_13450	COG3539	Fimbrial protein
FR848_13455	COG3121	Chaperone
FR848_13470	COG3539	Fimbrial protein
FR848_13480	COG0316	Belongs to the HesB IscA family
FR848_13485	COG0719	Fe-S assembly protein
FR848_13490	COG0396	ATPase activity
FR848_13495	COG0719	Fe-S assembly protein
FR848_13510	COG1376	ErfK ybiS ycfS ynhG family protein
FR848_13540	COG2271	Major facilitator Superfamily
FR848_13545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FR848_13570	COG1414	Transcriptional regulator
FR848_13605	COG2814	Major facilitator Superfamily
FR848_13635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_13640	COG1960	acyl-CoA dehydrogenase activity
FR848_13655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_13660	COG1116	anion transmembrane transporter activity
FR848_13665	COG4774	siderophore transport
FR848_13670	COG1120	ATPase activity
FR848_13675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_13680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_13700	COG0765	amino acid transport
FR848_13705	COG1126	abc transporter atp-binding protein
FR848_13715	COG1473	amidohydrolase
FR848_13720	COG3383	formate dehydrogenase (NAD+) activity
FR848_13725	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FR848_13750	COG1360	Flagellar Motor Protein
FR848_13865	COG1175	transmembrane transport
FR848_13895	COG1278	Cold shock
FR848_13925	COG0582	viral genome integration into host DNA
FR848_13930	COG3539	Fimbrial protein
FR848_13945	COG3121	Chaperone
FR848_13955	COG0582	viral genome integration into host DNA
FR848_13960	COG4993	Dehydrogenase
FR848_13965	COG4608	Belongs to the ABC transporter superfamily
FR848_13970	COG0444	Belongs to the ABC transporter superfamily
FR848_13985	COG4166	transmembrane transport
FR848_13995	COG0346	lactoylglutathione lyase activity
FR848_14000	COG1349	DNA-binding transcription factor activity
FR848_14015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR848_14020	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_14025	COG3111	PFAM Bacterial OB fold (BOF) protein
FR848_14030	COG4529	Protein conserved in bacteria
FR848_14045	COG2323	membrane
FR848_14050	COG1546	Belongs to the CinA family
FR848_14065	COG1294	oxidase, subunit
FR848_14070	COG1271	oxidase subunit
FR848_14075	COG3546	catalase activity
FR848_14080	COG3685	Protein conserved in bacteria
FR848_14085	COG3685	Protein conserved in bacteria
FR848_14090	COG3729	General stress protein
FR848_14115	COG0307	riboflavin synthase, alpha
FR848_14120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FR848_14125	COG2814	Major facilitator Superfamily
FR848_14130	COG0583	DNA-binding transcription factor activity
FR848_14145	COG2814	Major facilitator Superfamily
FR848_14150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FR848_14155	COG0791	NLP P60 protein
FR848_14160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FR848_14170	COG0346	lactoylglutathione lyase activity
FR848_14175	COG1902	pentaerythritol trinitrate reductase activity
FR848_14180	COG1309	transcriptional regulator
FR848_14185	COG3313	Fe-S protein
FR848_14190	COG4989	oxidoreductase activity
FR848_14205	COG1566	PFAM secretion protein HlyD family protein
FR848_14220	COG3706	GGDEF domain
FR848_14225	COG3133	Outer membrane lipoprotein
FR848_14235	COG3895	Periplasmic Protein
FR848_14255	COG0625	glutathione transferase activity
FR848_14265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FR848_14275	COG4659	FMN binding
FR848_14310	COG2723	6-phospho-beta-galactosidase activity
FR848_14320	COG0673	inositol 2-dehydrogenase activity
FR848_14335	COG0425	Belongs to the sulfur carrier protein TusA family
FR848_14340	COG2391	methyltransferase activity
FR848_14350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FR848_14355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_14355	COG1263	PTS System
FR848_14360	COG1609	Transcriptional regulator
FR848_14365	COG5339	Protein conserved in bacteria
FR848_14370	COG1482	cell wall glycoprotein biosynthetic process
FR848_14375	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_14375	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_14380	COG0114	fumarate hydratase activity
FR848_14390	COG2205	protein histidine kinase activity
FR848_14405	COG0386	Belongs to the glutathione peroxidase family
FR848_14415	COG0745	RESPONSE REGULATOR receiver
FR848_14430	COG3136	membrane protein required for alginate biosynthesis
FR848_14440	COG0531	amino acid
FR848_14455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR848_14460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FR848_14470	COG0589	response to stress
FR848_14475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR848_14480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR848_14485	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR848_14490	COG1473	amidohydrolase
FR848_14500	COG0583	DNA-binding transcription factor activity
FR848_14505	COG2840	Smr protein MutS2
FR848_14510	COG1414	Transcriptional regulator
FR848_14520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FR848_14525	COG0183	Belongs to the thiolase family
FR848_14535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR848_14540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_14545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_14545	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_14555	COG1053	succinate dehydrogenase
FR848_14565	COG4565	transcriptional regulatory protein
FR848_14570	COG3290	protein histidine kinase activity
FR848_14580	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_14585	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR848_14600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FR848_14610	COG0679	Auxin Efflux Carrier
FR848_14640	COG0628	permease
FR848_14665	COG3591	Belongs to the peptidase S1B family
FR848_14685	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FR848_14690	COG2814	Major facilitator Superfamily
FR848_14695	COG0583	DNA-binding transcription factor activity
FR848_14700	COG1940	carbohydrate kinase activity
FR848_14705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FR848_14715	COG3381	protein complex oligomerization
FR848_14720	COG3302	dmso reductase anchor subunit
FR848_14725	COG0437	4 iron, 4 sulfur cluster binding
FR848_14730	COG0243	molybdopterin cofactor binding
FR848_14745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR848_14760	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_14765	COG1063	alcohol dehydrogenase
FR848_14770	COG0477	Major facilitator Superfamily
FR848_14775	COG0246	Mannitol dehydrogenase
FR848_14780	COG0589	response to stress
FR848_14785	COG1802	Transcriptional regulator
FR848_14790	COG4221	oxidoreductase activity
FR848_14795	COG0339	signal peptide processing
FR848_14810	COG0339	signal peptide processing
FR848_14830	COG3122	Protein conserved in bacteria
FR848_14860	COG2223	nitrite transmembrane transporter activity
FR848_14880	COG2200	EAL domain
FR848_14925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FR848_14935	COG0559	Belongs to the binding-protein-dependent transport system permease family
FR848_14945	COG0411	ABC transporter
FR848_14965	COG2814	Major facilitator Superfamily
FR848_14970	COG0697	spore germination
FR848_14985	COG1846	Transcriptional regulator
FR848_15010	COG0039	L-malate dehydrogenase activity
FR848_15020	COG0583	DNA-binding transcription factor activity
FR848_15025	COG1012	belongs to the aldehyde dehydrogenase family
FR848_15040	COG2199	diguanylate cyclase activity
FR848_15090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_15095	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_15105	COG0477	Major facilitator Superfamily
FR848_15135	COG0477	Major facilitator Superfamily
FR848_15150	COG2011	ABC-type metal ion transport system permease component
FR848_15170	COG4628	conserved protein (DUF2132)
FR848_15180	COG1126	abc transporter atp-binding protein
FR848_15185	COG0765	amino acid transport
FR848_15190	COG0765	amino acid transport
FR848_15210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FR848_15215	COG2207	Transcriptional regulator
FR848_15225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FR848_15230	COG1446	asparaginase
FR848_15235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_15250	COG1120	ATPase activity
FR848_15255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR848_15260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_15280	COG3775	system Galactitol-specific IIC component
FR848_15285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR848_15290	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_15295	COG1070	Carbohydrate kinase
FR848_15305	COG1830	Aldolase
FR848_15320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_15325	COG1129	ABC transporter
FR848_15330	COG1879	ABC-type sugar transport system periplasmic component
FR848_15335	COG1609	Transcriptional regulator
FR848_15345	COG0693	protein deglycase activity
FR848_15360	COG0412	Dienelactone hydrolase
FR848_15365	COG0583	DNA-binding transcription factor activity
FR848_15390	COG2841	Protein conserved in bacteria
FR848_15425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_15440	COG4821	SIS domain
FR848_15485	COG0024	Methionine aminopeptidase
FR848_15490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR848_15520	COG3391	amine dehydrogenase activity
FR848_15525	COG4771	TonB-dependent receptor
FR848_15535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR848_15550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_15560	COG1609	Transcriptional regulator
FR848_15590	COG1652	LysM domain
FR848_15595	COG4771	TonB-dependent receptor
FR848_15600	COG1021	2,3-dihydroxybenzoate-AMP ligase
FR848_15620	COG3433	isochorismatase activity
FR848_15620	COG2226	methyltransferase
FR848_15620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR848_15635	COG1132	(ABC) transporter
FR848_15640	COG2814	Major facilitator Superfamily
FR848_15645	COG1169	isochorismate synthase
FR848_15655	COG1840	ABC-type Fe3 transport system, periplasmic component
FR848_15670	COG0814	amino acid
FR848_15675	COG1760	l-serine dehydratase
FR848_15775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FR848_15780	COG0022	dehydrogenase e1 component
FR848_15785	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR848_15790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR848_15805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FR848_15815	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_15825	COG0401	homolog of Blt101
FR848_15835	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR848_15840	COG2771	luxR family
FR848_15840	COG2200	EAL domain
FR848_15880	COG1082	Xylose isomerase domain protein TIM barrel
FR848_15885	COG0673	inositol 2-dehydrogenase activity
FR848_15890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR848_15895	COG1116	anion transmembrane transporter activity
FR848_15900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_15905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR848_15910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR848_15915	COG0076	glutamate decarboxylase activity
FR848_15930	COG0519	Catalyzes the synthesis of GMP from XMP
FR848_15930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR848_15945	COG0439	Biotin carboxylase
FR848_15960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR848_15960	COG1116	anion transmembrane transporter activity
FR848_15985	COG1280	lysine exporter protein (LysE YggA)
FR848_16030	COG2271	Major facilitator Superfamily
FR848_16040	COG0583	DNA-binding transcription factor activity
FR848_16045	COG0583	DNA-binding transcription factor activity
FR848_16055	COG1280	lysine exporter protein (LysE YggA)
FR848_16060	COG0243	molybdopterin cofactor binding
FR848_16065	COG3781	membrane
FR848_16080	COG1764	response to oxidative stress
FR848_16110	COG0488	(ABC) transporter
FR848_16135	COG1064	alcohol dehydrogenase
FR848_16165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_16175	COG2814	Major facilitator Superfamily
FR848_16190	COG2864	formate dehydrogenase
FR848_16195	COG0437	4 iron, 4 sulfur cluster binding
FR848_16205	COG0697	spore germination
FR848_16225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FR848_16230	COG1140	nitrate reductase beta subunit
FR848_16235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FR848_16240	COG2181	nitrate reductase activity
FR848_16245	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FR848_16250	COG1178	ABC-type Fe3 transport system permease component
FR848_16255	COG1840	ABC-type Fe3 transport system, periplasmic component
FR848_16260	COG3842	ATPase activity
FR848_16265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR848_16270	COG4977	sequence-specific DNA binding
FR848_16280	COG2211	Major facilitator Superfamily
FR848_16305	COG0625	glutathione transferase activity
FR848_16310	COG1609	Transcriptional regulator
FR848_16320	COG2271	Major facilitator Superfamily
FR848_16330	COG1126	abc transporter atp-binding protein
FR848_16350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_16370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FR848_16390	COG4772	TonB-dependent receptor
FR848_16395	COG3691	Protein conserved in bacteria
FR848_16410	COG2130	NADP-dependent
FR848_16425	COG1247	-acetyltransferase
FR848_16430	COG3238	Protein conserved in bacteria
FR848_16440	COG0747	negative chemotaxis
FR848_16445	COG1012	belongs to the aldehyde dehydrogenase family
FR848_16450	COG4677	pectinesterase activity
FR848_16455	COG0596	Alpha beta hydrolase
FR848_16480	COG1012	belongs to the aldehyde dehydrogenase family
FR848_16485	COG1177	transmembrane transport
FR848_16490	COG1176	ABC-type spermidine putrescine transport system, permease component I
FR848_16495	COG3842	ATPase activity
FR848_16500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR848_16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR848_16515	COG1271	oxidase subunit
FR848_16520	COG1294	oxidase, subunit
FR848_16535	COG0826	peptidase U32
FR848_16540	COG1396	sequence-specific DNA binding
FR848_16545	COG3135	benzoate transporter
FR848_16550	COG2207	Transcriptional regulator
FR848_16555	COG0697	spore germination
FR848_16565	COG0747	negative chemotaxis
FR848_16570	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR848_16575	COG0500	methyltransferase
FR848_16580	COG1275	C4-dicarboxylate transporter malic acid transport protein
FR848_16585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR848_16590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR848_16600	COG2272	Belongs to the type-B carboxylesterase lipase family
FR848_16605	COG5383	Protein conserved in bacteria
FR848_16610	COG3485	protocatechuate 3,4-dioxygenase
FR848_16615	COG3485	protocatechuate 3,4-dioxygenase
FR848_16620	COG0583	DNA-binding transcription factor activity
FR848_16650	COG3038	cytochrome b561
FR848_16670	COG3706	GGDEF domain
FR848_16675	COG0583	DNA-binding transcription factor activity
FR848_16680	COG0456	acetyltransferase
FR848_16685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR848_16690	COG1012	belongs to the aldehyde dehydrogenase family
FR848_16695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR848_16705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR848_16725	COG1538	Outer membrane efflux protein
FR848_16735	COG1643	Atp-dependent helicase
FR848_16750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR848_16755	COG3327	negative regulation of DNA-templated transcription, initiation
FR848_16760	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FR848_16765	COG0183	Belongs to the thiolase family
FR848_16770	COG2050	protein possibly involved in aromatic compounds catabolism
FR848_16775	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR848_16780	COG1024	Enoyl-CoA hydratase
FR848_16785	COG1024	Enoyl-CoA hydratase
FR848_16790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR848_16795	COG2151	metal-sulfur cluster biosynthetic enzyme
FR848_16800	COG3396	Phenylacetate-CoA oxygenase
FR848_16805	COG3460	Phenylacetate-CoA oxygenase
FR848_16810	COG3396	Phenylacetate-CoA oxygenase
FR848_16815	COG1012	belongs to the aldehyde dehydrogenase family
FR848_16815	COG2030	dehydratase
FR848_16835	COG3813	Protein conserved in bacteria
FR848_16850	COG0583	DNA-binding transcription factor activity
FR848_16875	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FR848_16880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR848_16900	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_16905	COG2378	regulation of single-species biofilm formation
FR848_16910	COG0406	alpha-ribazole phosphatase activity
FR848_16925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_16930	COG2207	Transcriptional regulator
FR848_16930	COG3708	Transcriptional regulator
FR848_16935	COG2207	Transcriptional regulator
FR848_16950	COG1566	PFAM secretion protein HlyD family protein
FR848_16975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FR848_17005	COG2072	flavoprotein involved in K transport
FR848_17010	COG0583	DNA-binding transcription factor activity
FR848_17015	COG1126	abc transporter atp-binding protein
FR848_17020	COG5285	phytanoyl-CoA dioxygenase
FR848_17035	COG1012	belongs to the aldehyde dehydrogenase family
FR848_17040	COG2207	Transcriptional regulator
FR848_17045	COG3784	Protein of unknown function (DUF1318)
FR848_17055	COG2911	Protein conserved in bacteria
FR848_17060	COG0586	Pfam SNARE associated Golgi protein
FR848_17065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR848_17070	COG3187	Heat shock protein
FR848_17075	COG3042	response to heat
FR848_17155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FR848_17155	COG0674	pyruvate-flavodoxin oxidoreductase activity
FR848_17155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FR848_17155	COG1013	pyruvate-flavodoxin oxidoreductase activity
FR848_17165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR848_17175	COG0589	response to stress
FR848_17200	COG0513	Belongs to the DEAD box helicase family
FR848_17215	COG1349	DNA-binding transcription factor activity
FR848_17220	COG0673	inositol 2-dehydrogenase activity
FR848_17225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR848_17230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR848_17250	COG3477	response to acidic pH
FR848_17255	COG2885	chlorophyll binding
FR848_17255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FR848_17275	COG0300	oxidoreductase activity
FR848_17285	COG0583	DNA-binding transcription factor activity
FR848_17310	COG0789	Transcriptional regulator
FR848_17320	COG0300	oxidoreductase activity
FR848_17335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FR848_17345	COG3272	Protein of unknown function (DUF1722)
FR848_17350	COG4580	involved in the transport of maltose and maltodextrins
FR848_17355	COG2211	Major facilitator Superfamily
FR848_17360	COG3507	Belongs to the glycosyl hydrolase 43 family
FR848_17455	COG0693	protein deglycase activity
FR848_17460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FR848_17465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_17480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FR848_17485	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FR848_17495	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FR848_17500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_17505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR848_17510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR848_17530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR848_17535	COG1045	serine acetyltransferase
FR848_17545	COG0765	amino acid transport
FR848_17550	COG1126	abc transporter atp-binding protein
FR848_17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_17560	COG1605	Chorismate mutase
FR848_17570	COG0765	amino acid transport
FR848_17575	COG0765	amino acid transport
FR848_17580	COG4221	oxidoreductase activity
FR848_17600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FR848_17605	COG1984	allophanate hydrolase subunit 2
FR848_17610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FR848_17620	COG0697	spore germination
FR848_17625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR848_17630	COG0439	Biotin carboxylase
FR848_17635	COG0511	ligase activity, forming carbon-carbon bonds
FR848_17655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_17670	COG2814	Major facilitator Superfamily
FR848_17675	COG1464	Belongs to the NlpA lipoprotein family
FR848_17680	COG2011	ABC-type metal ion transport system permease component
FR848_17695	COG4166	transmembrane transport
FR848_17700	COG2866	Carboxypeptidase
FR848_17705	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_17710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FR848_17715	COG3180	Ammonia monooxygenase
FR848_17720	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FR848_17730	COG3106	COG3106 Predicted ATPase
FR848_17735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR848_17745	COG1983	PspC domain protein
FR848_17755	COG1842	Phage shock protein A
FR848_17760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FR848_17770	COG1473	amidohydrolase
FR848_17785	COG4166	transmembrane transport
FR848_17790	COG4168	peptide transport system, permease
FR848_17795	COG4171	peptide transport system, permease
FR848_17805	COG4172	Belongs to the ABC transporter superfamily
FR848_17810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR848_17815	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_17815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_17830	COG1349	DNA-binding transcription factor activity
FR848_17840	COG0023	Translation Initiation Factor
FR848_17850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FR848_17855	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FR848_17860	COG0671	phosphoesterase, PA-phosphatase related
FR848_17870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FR848_17885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR848_17895	COG0616	signal peptide processing
FR848_17905	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_17915	COG2207	Transcriptional regulator
FR848_17925	COG2211	Major facilitator Superfamily
FR848_17930	COG1187	pseudouridine synthase activity
FR848_17935	COG0009	L-threonylcarbamoyladenylate synthase
FR848_17945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR848_17950	COG0512	Glutamine amidotransferase of anthranilate synthase
FR848_17950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FR848_17955	COG0134	indole-3-glycerol-phosphate synthase activity
FR848_17955	COG0135	phosphoribosylanthranilate isomerase activity
FR848_17975	COG1063	alcohol dehydrogenase
FR848_17980	COG0583	DNA-binding transcription factor activity
FR848_17990	COG3708	Transcriptional regulator
FR848_17990	COG2207	Transcriptional regulator
FR848_18005	COG3047	cAMP biosynthetic process
FR848_18020	COG0038	chloride channel
FR848_18030	COG1607	acyl-coa hydrolase
FR848_18040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR848_18045	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_18050	COG1988	membrane-bound metal-dependent
FR848_18065	COG0753	catalase activity
FR848_18075	COG1486	melibiose metabolic process
FR848_18080	COG1917	Cupin 2, conserved barrel domain protein
FR848_18080	COG2169	Transcriptional regulator
FR848_18085	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR848_18090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_18095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_18100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR848_18110	COG0322	excinuclease ABC activity
FR848_18115	COG4907	membrane protein (DUF2207)
FR848_18120	COG1704	LemA family
FR848_18125	COG3678	ATP-independent chaperone mediated protein folding
FR848_18145	COG3138	arginine N-succinyltransferase
FR848_18155	COG0708	Exodeoxyribonuclease III
FR848_18160	COG0398	Pfam SNARE associated Golgi protein
FR848_18165	COG0398	Pfam SNARE associated Golgi protein
FR848_18170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR848_18175	COG4134	Bacterial extracellular solute-binding protein
FR848_18180	COG4135	transport system, permease component
FR848_18185	COG4136	ATPase activity
FR848_18190	COG2897	thiosulfate sulfurtransferase activity
FR848_18195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR848_18200	COG0494	nUDIX hydrolase
FR848_18210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR848_18215	COG0709	Synthesizes selenophosphate from selenide and ATP
FR848_18230	COG0778	Nitroreductase
FR848_18235	COG0616	signal peptide processing
FR848_18240	COG0252	asparaginase activity
FR848_18245	COG1335	isochorismatase
FR848_18250	COG2814	Major facilitator Superfamily
FR848_18255	COG1349	DNA-binding transcription factor activity
FR848_18260	COG0667	Aldo Keto reductase
FR848_18265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_18270	COG0191	fructose-bisphosphate aldolase activity
FR848_18275	COG1063	alcohol dehydrogenase
FR848_18280	COG2271	Major facilitator Superfamily
FR848_18285	COG1063	alcohol dehydrogenase
FR848_18295	COG1403	HNH endonuclease
FR848_18300	COG3139	Protein of unknown function (DUF1315)
FR848_18310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR848_18320	COG0656	L-ascorbic acid biosynthetic process
FR848_18325	COG3713	MltA-interacting MipA family protein
FR848_18330	COG2766	serine protein kinase
FR848_18340	COG0859	PFAM glycosyl transferase family 9
FR848_18350	COG2199	diguanylate cyclase activity
FR848_18355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR848_18365	COG2207	Transcriptional regulator
FR848_18370	COG2807	transmembrane transport
FR848_18375	COG0504	CTP synthase activity
FR848_18380	COG1683	Conserved Protein
FR848_18385	COG3189	MarR family transcriptional regulator
FR848_18390	COG3042	response to heat
FR848_18395	COG2199	diguanylate cyclase activity
FR848_18395	COG2203	Gaf domain
FR848_18415	COG3182	Iron-regulated membrane protein
FR848_18425	COG1560	Kdo2-lipid A biosynthetic process
FR848_18430	COG2226	methyltransferase
FR848_18435	COG1595	DNA-templated transcription, initiation
FR848_18440	COG3712	iron ion homeostasis
FR848_18445	COG4772	TonB-dependent receptor
FR848_18450	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FR848_18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_18465	COG1120	ATPase activity
FR848_18475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR848_18480	COG3706	GGDEF domain
FR848_18485	COG1943	Transposase
FR848_18490	COG0538	isocitrate dehydrogenase activity
FR848_18495	COG1187	pseudouridine synthase activity
FR848_18515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FR848_18520	COG2814	Major facilitator Superfamily
FR848_18530	COG0745	RESPONSE REGULATOR receiver
FR848_18535	COG2205	protein histidine kinase activity
FR848_18540	COG2850	peptidyl-arginine hydroxylation
FR848_18555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FR848_18560	COG1177	transmembrane transport
FR848_18565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR848_18575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR848_18580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR848_18585	COG0698	ribose 5-phosphate isomerase
FR848_18600	COG3395	kinase activity
FR848_18615	COG2390	Transcriptional regulator
FR848_18620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FR848_18630	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR848_18640	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR848_18645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FR848_18650	COG1388	LysM domain
FR848_18650	COG1376	ErfK ybiS ycfS ynhG family protein
FR848_18660	COG1309	transcriptional regulator
FR848_18670	COG3134	Outer membrane lipoprotein
FR848_18675	COG1252	NADH dehydrogenase
FR848_18700	COG5633	Lipoprotein
FR848_18705	COG0537	adenosine 5'-monophosphoramidase activity
FR848_18715	COG4773	Receptor
FR848_18725	COG0084	hydrolase, TatD family'
FR848_18730	COG0470	DNA polymerase III
FR848_18740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FR848_18745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR848_18750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR848_18760	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_18765	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FR848_18785	COG1399	metal-binding, possibly nucleic acid-binding protein
FR848_18790	COG0424	maF-like protein
FR848_18805	COG1530	ribonuclease E activity
FR848_18810	COG0583	DNA-binding transcription factor activity
FR848_18815	COG2814	Major facilitator Superfamily
FR848_18825	COG0673	inositol 2-dehydrogenase activity
FR848_18835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR848_18845	COG2999	glutathione oxidoreductase activity
FR848_18885	COG1560	Kdo2-lipid A biosynthetic process
FR848_18900	COG5645	(Lipo)protein
FR848_18940	COG3381	protein complex oligomerization
FR848_18960	COG0583	DNA-binding transcription factor activity
FR848_18970	COG1335	isochorismatase
FR848_18990	COG3850	Histidine kinase
FR848_18990	COG5002	protein histidine kinase activity
FR848_19010	COG1702	phosphate starvation-inducible protein PhoH
FR848_19015	COG2837	iron assimilation
FR848_19020	COG2822	iron ion transport
FR848_19030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR848_19040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR848_19055	COG1309	transcriptional regulator
FR848_19090	COG2233	PERMEase
FR848_19100	COG3729	General stress protein
FR848_19130	COG0531	amino acid
FR848_19140	COG0174	glutamine synthetase
FR848_19145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FR848_19150	COG1917	Cupin 2, conserved barrel domain protein
FR848_19150	COG1396	sequence-specific DNA binding
FR848_19155	COG1012	belongs to the aldehyde dehydrogenase family
FR848_19160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR848_19165	COG0583	DNA-binding transcription factor activity
FR848_19170	COG0473	3-isopropylmalate dehydrogenase activity
FR848_19175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_19175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_19175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR848_19180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_19185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_19195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR848_19200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR848_19210	COG2207	Transcriptional regulator
FR848_19215	COG3706	GGDEF domain
FR848_19235	COG0287	Prephenate dehydrogenase
FR848_19235	COG1605	Chorismate mutase
FR848_19245	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FR848_19260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FR848_19325	COG1953	Uracil, thiamine, allantoin
FR848_19330	COG0402	S-adenosylhomocysteine deaminase activity
FR848_19335	COG2351	hydroxyisourate hydrolase activity
FR848_19345	COG2233	PERMEase
FR848_19350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR848_19425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR848_19435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR848_19450	COG5002	protein histidine kinase activity
FR848_19455	COG0745	RESPONSE REGULATOR receiver
FR848_19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_19475	COG1278	Cold shock
FR848_19480	COG1278	Cold shock
FR848_19485	COG0471	metal ion transport
FR848_19500	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FR848_19520	COG3052	prosthetic group binding
FR848_19525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FR848_19530	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR848_19535	COG2814	Major facilitator Superfamily
FR848_19540	COG2828	Protein conserved in bacteria
FR848_19545	COG0583	DNA-binding transcription factor activity
FR848_19565	COG0765	amino acid transport
FR848_19600	COG0156	8-amino-7-oxononanoate synthase activity
FR848_19625	COG0604	alcohol dehydrogenase
FR848_19630	COG0300	oxidoreductase activity
FR848_19645	COG1486	melibiose metabolic process
FR848_19650	COG2207	Transcriptional regulator
FR848_19665	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_19675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_19685	COG1126	abc transporter atp-binding protein
FR848_19690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR848_19700	COG0006	proline dipeptidase activity
FR848_19705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR848_19710	COG0504	CTP synthase activity
FR848_19720	COG2188	Transcriptional regulator
FR848_19730	COG3715	PTS system
FR848_19735	COG3716	PTS system mannose fructose sorbose family IID component
FR848_19740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_19745	COG4821	SIS domain
FR848_19755	COG4821	SIS domain
FR848_19780	COG0670	Belongs to the BI1 family
FR848_19795	COG2207	Transcriptional regulator
FR848_19800	COG1881	PFAM PEBP family protein
FR848_19825	COG0438	transferase activity, transferring glycosyl groups
FR848_19830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_19835	COG2274	protein secretion by the type I secretion system
FR848_19850	COG1832	CoA-binding protein
FR848_19860	COG0210	DNA helicase
FR848_19865	COG3304	Inner membrane component domain
FR848_19870	COG1289	transmembrane transporter activity
FR848_19875	COG3070	regulator of competence-specific genes
FR848_19895	COG1067	ATP-dependent peptidase activity
FR848_19905	COG3130	regulation of translation
FR848_19910	COG3009	Protein conserved in bacteria
FR848_19915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR848_19915	COG3008	intermembrane lipid transfer
FR848_19920	COG2995	paraquat-inducible protein a
FR848_19925	COG0488	(ABC) transporter
FR848_19935	COG3217	Mosc domain protein beta barrel domain protein
FR848_19935	COG0633	Ferredoxin
FR848_19950	COG0431	NADPH-dependent FMN reductase
FR848_19955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_19960	COG1116	anion transmembrane transporter activity
FR848_19965	COG0308	aminopeptidase N
FR848_19980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR848_19985	COG1448	Aminotransferase
FR848_19990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR848_19995	COG3108	Peptidase M15
FR848_20000	COG2989	Protein conserved in bacteria
FR848_20010	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FR848_20020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR848_20025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR848_20030	COG3173	Aminoglycoside phosphotransferase
FR848_20045	COG3214	Protein conserved in bacteria
FR848_20055	COG1132	(ABC) transporter
FR848_20060	COG0658	competence protein
FR848_20060	COG2333	competence protein COMEC
FR848_20070	COG0539	negative regulation of cytoplasmic translation
FR848_20090	COG2323	membrane
FR848_20095	COG1944	ATP diphosphatase activity
FR848_20100	COG2116	formate transmembrane transporter activity
FR848_20105	COG1882	Formate acetyltransferase
FR848_20110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR848_20130	COG3959	Transketolase, thiamine diphosphate binding domain
FR848_20135	COG3958	Transketolase
FR848_20140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_20145	COG0477	Major facilitator Superfamily
FR848_20150	COG3302	dmso reductase anchor subunit
FR848_20155	COG0437	4 iron, 4 sulfur cluster binding
FR848_20160	COG0243	molybdopterin cofactor binding
FR848_20170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FR848_20180	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR848_20180	COG1674	ftsk spoiiie
FR848_20190	COG0492	ferredoxin-NADP+ reductase activity
FR848_20195	COG4988	ABC transporter
FR848_20200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FR848_20215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FR848_20220	COG0542	response to heat
FR848_20230	COG1278	Cold shock
FR848_20240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_20245	COG3593	DNA synthesis involved in DNA repair
FR848_20250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR848_20255	COG2431	L-lysine efflux transmembrane transporter activity
FR848_20265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR848_20275	COG0028	Belongs to the TPP enzyme family
FR848_20280	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FR848_20285	COG0702	epimerase
FR848_20290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR848_20295	COG3023	N-Acetylmuramoyl-L-alanine amidase
FR848_20300	COG0393	Putative heavy-metal-binding
FR848_20310	COG1126	abc transporter atp-binding protein
FR848_20315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_20320	COG4215	(ABC) transporter
FR848_20325	COG4160	amino acid transport
FR848_20330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_20335	COG5002	protein histidine kinase activity
FR848_20340	COG0745	RESPONSE REGULATOR receiver
FR848_20355	COG1177	transmembrane transport
FR848_20360	COG1176	ABC-type spermidine putrescine transport system, permease component I
FR848_20365	COG3842	ATPase activity
FR848_20370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR848_20385	COG0778	Nitroreductase
FR848_20395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR848_20445	COG1192	Involved in chromosome partitioning
FR848_20480	COG3226	Transcriptional regulator
FR848_20485	COG0738	Major facilitator superfamily
FR848_20490	COG0561	phosphatase activity
FR848_20495	COG2814	Major facilitator Superfamily
FR848_20500	COG0671	phosphoesterase, PA-phosphatase related
FR848_20505	COG1349	DNA-binding transcription factor activity
FR848_20510	COG1686	Belongs to the peptidase S11 family
FR848_20515	COG0625	glutathione transferase activity
FR848_20520	COG2133	pyrroloquinoline quinone binding
FR848_20555	COG0747	negative chemotaxis
FR848_20565	COG1446	asparaginase
FR848_20575	COG0303	'Molybdopterin
FR848_20580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR848_20585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR848_20595	COG0561	phosphatase activity
FR848_20605	COG1609	Transcriptional regulator
FR848_20610	COG2271	Major facilitator Superfamily
FR848_20625	COG0488	(ABC) transporter
FR848_20635	COG1376	ErfK ybiS ycfS ynhG family protein
FR848_20640	COG2188	Transcriptional regulator
FR848_20645	COG2723	6-phospho-beta-galactosidase activity
FR848_20650	COG0667	Aldo Keto reductase
FR848_20655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FR848_20660	COG1321	iron dependent repressor
FR848_20670	COG2194	sulfuric ester hydrolase activity
FR848_20675	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FR848_20690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_20695	COG0765	amino acid transport
FR848_20700	COG1126	abc transporter atp-binding protein
FR848_20710	COG0668	transmembrane transport
FR848_20725	COG4774	siderophore transport
FR848_20735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR848_20745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FR848_20755	COG0513	Belongs to the DEAD box helicase family
FR848_20760	COG3958	Transketolase
FR848_20765	COG3959	Transketolase, thiamine diphosphate binding domain
FR848_20770	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_20775	COG2271	Major facilitator Superfamily
FR848_20785	COG0583	DNA-binding transcription factor activity
FR848_20790	COG1309	transcriptional regulator
FR848_20795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_20800	COG1131	(ABC) transporter
FR848_20805	COG0842	Transport permease protein
FR848_20810	COG0842	Transport permease protein
FR848_20820	COG3568	Endonuclease Exonuclease Phosphatase
FR848_20825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR848_20830	COG0392	lysyltransferase activity
FR848_20835	COG0670	Belongs to the BI1 family
FR848_20840	COG0314	molybdopterin synthase activity
FR848_20845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FR848_20855	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR848_20875	COG0745	RESPONSE REGULATOR receiver
FR848_20910	COG2226	methyltransferase
FR848_20925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR848_20930	COG1881	PFAM PEBP family protein
FR848_20960	COG4677	pectinesterase activity
FR848_20975	COG0789	Transcriptional regulator
FR848_20980	COG2200	EAL domain
FR848_21015	COG0561	phosphatase activity
FR848_21025	COG4149	molybdate abc transporter
FR848_21030	COG0725	ABC transporter, periplasmic molybdate-binding protein
FR848_21040	COG2005	Transcriptional regulator
FR848_21040	COG3585	molybdate ion transport
FR848_21045	COG1119	ATPase activity
FR848_21050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR848_21055	COG1085	galactose-1-phosphate uridylyltransferase
FR848_21065	COG2017	converts alpha-aldose to the beta-anomer
FR848_21075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR848_21095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FR848_21130	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FR848_21135	COG2885	chlorophyll binding
FR848_21145	COG3064	Membrane
FR848_21150	COG0848	biopolymer transport protein
FR848_21155	COG0811	peptide transport
FR848_21160	COG0824	Thioesterase
FR848_21165	COG3790	cyd operon protein YbgE
FR848_21170	COG4890	Cyd operon protein YbgT
FR848_21175	COG1294	oxidase, subunit
FR848_21180	COG1271	oxidase subunit
FR848_21185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FR848_21195	COG4865	methylaspartate mutase activity
FR848_21200	COG3799	methylaspartate ammonia-lyase activity
FR848_21215	COG1301	dicarboxylic acid transport
FR848_21225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_21225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FR848_21240	COG0583	DNA-binding transcription factor activity
FR848_21250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FR848_21260	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR848_21265	COG0567	Dehydrogenase, E1 component
FR848_21270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR848_21275	COG1053	succinate dehydrogenase
FR848_21280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FR848_21285	COG2009	succinate dehydrogenase
FR848_21290	COG0372	Belongs to the citrate synthase family
FR848_21320	COG1984	allophanate hydrolase subunit 2
FR848_21325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FR848_21330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR848_21340	COG0415	Belongs to the DNA photolyase family
FR848_21370	COG2205	protein histidine kinase activity
FR848_21375	COG0745	RESPONSE REGULATOR receiver
FR848_21385	COG3623	hexulose-6-phosphate isomerase
FR848_21390	COG1070	Carbohydrate kinase
FR848_21395	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_21400	COG1129	ABC transporter
FR848_21405	COG1879	ABC-type sugar transport system periplasmic component
FR848_21410	COG1063	alcohol dehydrogenase
FR848_21415	COG1349	DNA-binding transcription factor activity
FR848_21425	COG0033	Phosphoglucomutase
FR848_21430	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FR848_21435	COG0596	Alpha beta hydrolase
FR848_21450	COG0735	belongs to the Fur family
FR848_21455	COG0583	DNA-binding transcription factor activity
FR848_21460	COG1053	succinate dehydrogenase
FR848_21505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FR848_21510	COG1940	carbohydrate kinase activity
FR848_21510	COG1846	Transcriptional regulator
FR848_21515	COG0647	UMP catabolic process
FR848_21520	COG0367	asparagine synthase
FR848_21560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR848_21570	COG1702	phosphate starvation-inducible protein PhoH
FR848_21575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FR848_21580	COG4535	Mg2 and Co2 transporter CorC
FR848_21595	COG0765	amino acid transport
FR848_21600	COG0765	amino acid transport
FR848_21605	COG1126	abc transporter atp-binding protein
FR848_21610	COG2831	hemolysin activation secretion protein
FR848_21620	COG2888	peptidyl-tyrosine sulfation
FR848_21635	COG1466	dna polymerase III delta subunit
FR848_21645	COG0406	alpha-ribazole phosphatase activity
FR848_21650	COG0799	negative regulation of ribosome biogenesis
FR848_21660	COG0768	penicillin binding
FR848_21665	COG0772	Belongs to the SEDS family
FR848_21670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR848_21675	COG1686	Belongs to the peptidase S11 family
FR848_21690	COG0583	DNA-binding transcription factor activity
FR848_21700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR848_21705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR848_21715	COG1278	Cold shock
FR848_21725	COG3069	C4-dicarboxylate transmembrane transporter activity
FR848_21730	COG3719	Belongs to the RNase T2 family
FR848_21735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR848_21740	COG0589	response to stress
FR848_21745	COG3634	alkyl hydroperoxide reductase activity
FR848_21755	COG0450	alkyl hydroperoxide reductase
FR848_21760	COG0583	DNA-binding transcription factor activity
FR848_21765	COG3969	phosphoadenosine phosphosulfate
FR848_21770	COG1475	DNA binding
FR848_21775	COG0436	Aminotransferase
FR848_21780	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FR848_21785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FR848_21805	COG1129	ABC transporter
FR848_21810	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_21825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR848_21840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR848_21850	COG0402	S-adenosylhomocysteine deaminase activity
FR848_21860	COG0483	inositol monophosphate 1-phosphatase activity
FR848_21865	COG2271	Major facilitator Superfamily
FR848_21895	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_21900	COG1129	ABC transporter
FR848_21905	COG0371	Dehydrogenase
FR848_21920	COG2879	small protein
FR848_21925	COG1966	Carbon starvation protein
FR848_21940	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_21945	COG1535	isochorismatase
FR848_21945	COG3433	isochorismatase activity
FR848_21950	COG1021	2,3-dihydroxybenzoate-AMP ligase
FR848_21955	COG1169	isochorismate synthase
FR848_21960	COG4592	Periplasmic binding protein
FR848_21980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_21985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_21990	COG1120	ATPase activity
FR848_21995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FR848_21995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR848_22000	COG3251	PFAM MbtH domain protein
FR848_22005	COG2382	esterase
FR848_22010	COG4771	TonB-dependent receptor
FR848_22015	COG2977	Belongs to the P-Pant transferase superfamily
FR848_22020	COG3958	Transketolase
FR848_22025	COG3959	Transketolase, thiamine diphosphate binding domain
FR848_22030	COG2390	Transcriptional regulator
FR848_22035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FR848_22040	COG1879	ABC-type sugar transport system periplasmic component
FR848_22050	COG1129	ABC transporter
FR848_22055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_22065	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_22075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR848_22105	COG0601	transmembrane transport
FR848_22115	COG0444	Belongs to the ABC transporter superfamily
FR848_22120	COG4608	Belongs to the ABC transporter superfamily
FR848_22130	COG4221	oxidoreductase activity
FR848_22140	COG0765	amino acid transport
FR848_22160	COG1280	lysine exporter protein (LysE YggA)
FR848_22180	COG0154	amidase activity
FR848_22185	COG0444	Belongs to the ABC transporter superfamily
FR848_22190	COG4608	Belongs to the ABC transporter superfamily
FR848_22195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR848_22215	COG3698	Phosphodiester glycosidase
FR848_22245	COG4774	siderophore transport
FR848_22265	COG2315	Protein conserved in bacteria
FR848_22270	COG0778	Nitroreductase
FR848_22340	COG1621	beta-fructofuranosidase activity
FR848_22345	COG3716	PTS system mannose fructose sorbose family IID component
FR848_22350	COG3715	PTS system
FR848_22355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_22360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_22360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_22370	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FR848_22370	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FR848_22380	COG0477	Major facilitator Superfamily
FR848_22385	COG0668	transmembrane transport
FR848_22395	COG0494	nUDIX hydrolase
FR848_22415	COG3188	usher protein
FR848_22430	COG2771	luxR family
FR848_22435	COG0583	DNA-binding transcription factor activity
FR848_22440	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_22460	COG2211	Major facilitator Superfamily
FR848_22465	COG1113	amino acid transport
FR848_22475	COG0667	Aldo Keto reductase
FR848_22480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_22485	COG1473	amidohydrolase
FR848_22510	COG4139	cobalamin transport
FR848_22515	COG1120	ATPase activity
FR848_22555	COG3711	transcriptional antiterminator
FR848_22560	COG2723	6-phospho-beta-galactosidase activity
FR848_22565	COG2190	(PTS) system
FR848_22565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_22565	COG1263	PTS System
FR848_22570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_22575	COG1129	ABC transporter
FR848_22590	COG0673	inositol 2-dehydrogenase activity
FR848_22600	COG2367	Beta-lactamase
FR848_22620	COG3104	oligopeptide transport
FR848_22625	COG1982	Orn Lys Arg decarboxylase major
FR848_22630	COG0531	amino acid
FR848_22640	COG3710	Transcriptional regulator
FR848_22650	COG0583	DNA-binding transcription factor activity
FR848_22660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR848_22670	COG2808	Putative FMN-binding domain
FR848_22690	COG2501	S4 domain
FR848_22700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR848_22710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FR848_22715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FR848_22735	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FR848_22740	COG4181	ATPase activity
FR848_22745	COG2755	lipolytic protein G-D-S-L family
FR848_22750	COG0300	oxidoreductase activity
FR848_22755	COG3118	belongs to the thioredoxin family
FR848_22760	COG0390	transport system, permease component
FR848_22765	COG4619	ABC transporter
FR848_22770	COG0330	HflC and HflK could
FR848_22775	COG1585	Membrane protein implicated in regulation of membrane protease activity
FR848_22805	COG0811	peptide transport
FR848_22825	COG3735	TraB family
FR848_22830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR848_22840	COG2223	nitrite transmembrane transporter activity
FR848_22845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR848_22845	COG4651	solute:proton antiporter activity
FR848_22850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_22880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FR848_22890	COG2832	Protein of unknown function (DUF454)
FR848_22895	COG3923	Primosomal replication protein n
FR848_22910	COG3264	Mechanosensitive ion channel
FR848_22910	COG1196	nuclear chromosome segregation
FR848_22915	COG1309	transcriptional regulator
FR848_22920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_22925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR848_22940	COG0110	maltose O-acetyltransferase activity
FR848_22960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FR848_22980	COG1263	PTS System
FR848_22980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_22985	COG1874	Beta-galactosidase
FR848_22990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FR848_22995	COG3833	ABC-type maltose transport systems, permease component
FR848_23000	COG1175	transmembrane transport
FR848_23005	COG2182	Extracellular solute-binding protein
FR848_23015	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FR848_23030	COG5507	3-demethylubiquinone-9 3-methyltransferase
FR848_23035	COG2364	Membrane
FR848_23065	COG3695	enzyme binding
FR848_23070	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FR848_23075	COG1946	Acyl-CoA thioesterase
FR848_23080	COG0004	ammonium transporteR
FR848_23085	COG0347	Belongs to the P(II) protein family
FR848_23095	COG1132	(ABC) transporter
FR848_23100	COG1132	(ABC) transporter
FR848_23105	COG1522	sequence-specific DNA binding
FR848_23120	COG4533	DNA binding
FR848_23130	COG0824	Thioesterase
FR848_23135	COG1555	photosystem II stabilization
FR848_23145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_23150	COG0776	regulation of translation
FR848_23155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FR848_23185	COG0271	Belongs to the BolA IbaG family
FR848_23190	COG3056	Lipoprotein
FR848_23195	COG2223	nitrite transmembrane transporter activity
FR848_23200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR848_23205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR848_23210	COG1845	cytochrome c oxidase, subunit III
FR848_23215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FR848_23230	COG1414	Transcriptional regulator
FR848_23270	COG2211	Major facilitator Superfamily
FR848_23275	COG0673	inositol 2-dehydrogenase activity
FR848_23280	COG2814	Major facilitator Superfamily
FR848_23290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FR848_23310	COG0142	geranyltranstransferase activity
FR848_23320	COG0667	Aldo Keto reductase
FR848_23325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FR848_23345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR848_23345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR848_23355	COG4238	major outer membrane lipoprotein
FR848_23380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR848_23385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR848_23390	COG1862	Preprotein translocase
FR848_23405	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FR848_23410	COG0450	alkyl hydroperoxide reductase
FR848_23425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FR848_23435	COG1335	isochorismatase
FR848_23440	COG0583	DNA-binding transcription factor activity
FR848_23445	COG0366	Alpha amylase catalytic
FR848_23455	COG1114	Component of the transport system for branched-chain amino acids
FR848_23470	COG0420	3'-5' exonuclease activity
FR848_23475	COG0419	ATPase involved in DNA repair
FR848_23485	COG1940	carbohydrate kinase activity
FR848_23500	COG4126	flavin adenine dinucleotide binding
FR848_23510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FR848_23515	COG3416	Protein conserved in bacteria
FR848_23525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FR848_23535	COG1785	Belongs to the alkaline phosphatase family
FR848_23545	COG1609	Transcriptional regulator
FR848_23555	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_23570	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR848_23590	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FR848_23600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FR848_23605	COG0113	porphobilinogen synthase activity
FR848_23610	COG1943	Transposase
FR848_23620	COG2175	clavaminate synthase activity
FR848_23625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR848_23635	COG4521	taurine ABC transporter
FR848_23650	COG2271	Major facilitator Superfamily
FR848_23655	COG1840	ABC-type Fe3 transport system, periplasmic component
FR848_23665	COG3842	ATPase activity
FR848_23670	COG2040	homocysteine
FR848_23675	COG0833	amino acid
FR848_23680	COG5434	Belongs to the glycosyl hydrolase 28 family
FR848_23690	COG4303	Ethanolamine ammonia lyase large subunit
FR848_23695	COG4302	ethanolamine ammonia-lyase activity
FR848_23720	COG0411	ABC transporter
FR848_23725	COG0410	ABC transporter
FR848_23735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_23740	COG1126	abc transporter atp-binding protein
FR848_23745	COG0765	amino acid transport
FR848_23750	COG0765	amino acid transport
FR848_23765	COG3188	usher protein
FR848_23790	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FR848_23800	COG3639	organic phosphonate transmembrane transporter activity
FR848_23820	COG3118	belongs to the thioredoxin family
FR848_23835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR848_23840	COG0583	DNA-binding transcription factor activity
FR848_23845	COG0791	NLP P60 protein
FR848_23850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR848_23855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FR848_23860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FR848_23945	COG2814	Major facilitator Superfamily
FR848_23960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR848_23990	COG2986	histidine ammonia-lyase
FR848_24000	COG2188	Transcriptional regulator
FR848_24010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR848_24020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR848_24030	COG0477	Major facilitator Superfamily
FR848_24040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FR848_24045	COG3153	acetyltransferase
FR848_24060	COG0246	Mannitol dehydrogenase
FR848_24065	COG2186	Transcriptional regulator
FR848_24085	COG1012	belongs to the aldehyde dehydrogenase family
FR848_24090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR848_24100	COG1596	polysaccharide export
FR848_24120	COG0463	Glycosyl transferase, family 2
FR848_24125	COG0438	transferase activity, transferring glycosyl groups
FR848_24130	COG0297	glycogen (starch) synthase activity
FR848_24130	COG0438	transferase activity, transferring glycosyl groups
FR848_24145	COG1045	serine acetyltransferase
FR848_24165	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR848_24170	COG0454	-acetyltransferase
FR848_24185	COG2991	Protein conserved in bacteria
FR848_24200	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR848_24205	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR848_24220	COG3034	peptidoglycan biosynthetic process
FR848_24225	COG0121	glutamine amidotransferase
FR848_24240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR848_24250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR848_24260	COG2226	methyltransferase
FR848_24270	COG0741	lytic transglycosylase activity
FR848_24270	COG1388	LysM domain
FR848_24275	COG2226	methyltransferase
FR848_24285	COG2814	Major facilitator Superfamily
FR848_24290	COG0583	DNA-binding transcription factor activity
FR848_24330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR848_24340	COG2011	ABC-type metal ion transport system permease component
FR848_24345	COG1464	Belongs to the NlpA lipoprotein family
FR848_24355	COG1720	tRNA m6t6A37 methyltransferase activity
FR848_24365	COG0791	NLP P60 protein
FR848_24370	COG3015	lipoprotein NlpE involved in copper resistance
FR848_24375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FR848_24380	COG4681	YaeQ
FR848_24390	COG4568	rho-dependent transcription termination
FR848_24400	COG0346	lactoylglutathione lyase activity
FR848_24445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR848_24450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FR848_24460	COG0750	zinc metalloprotease
FR848_24465	COG0575	Belongs to the CDS family
FR848_24495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FR848_24505	COG0024	Methionine aminopeptidase
FR848_24510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FR848_24530	COG3835	regulator
FR848_24535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR848_24555	COG2860	membrane
FR848_24575	COG5464	transposase or invertase
FR848_24580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR848_24585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR848_24590	COG1120	ATPase activity
FR848_24595	COG4774	siderophore transport
FR848_24600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR848_24685	COG1643	Atp-dependent helicase
FR848_24690	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FR848_24700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR848_24710	COG0617	tRNA 3'-terminal CCA addition
FR848_24715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR848_24735	COG3539	Fimbrial protein
FR848_24740	COG3121	Chaperone
FR848_24745	COG3188	usher protein
FR848_24770	COG0726	polysaccharide deacetylase
FR848_24775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_24780	COG0842	Transport permease protein
FR848_24785	COG1131	(ABC) transporter
FR848_24790	COG0288	reversible hydration of carbon dioxide
FR848_24800	COG4993	Dehydrogenase
FR848_24805	COG2132	Multicopper oxidase
FR848_24820	COG0545	Peptidyl-prolyl cis-trans isomerase
FR848_24835	COG1349	DNA-binding transcription factor activity
FR848_24865	COG3064	Membrane
FR848_24880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR848_24885	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR848_24890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FR848_24895	COG2186	Transcriptional regulator
FR848_24905	COG1113	amino acid transport
FR848_24910	COG2211	Major facilitator Superfamily
FR848_24915	COG3940	Belongs to the glycosyl hydrolase 43 family
FR848_24920	COG3725	Membrane protein required for beta-lactamase induction
FR848_24935	COG4969	Belongs to the N-Me-Phe pilin family
FR848_24940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR848_24945	COG1459	type II secretion system
FR848_24955	COG0237	dephospho-CoA kinase activity
FR848_24965	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FR848_24970	COG0494	nUDIX hydrolase
FR848_24990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR848_24995	COG0849	cell division
FR848_25005	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR848_25020	COG0772	Belongs to the SEDS family
FR848_25035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FR848_25045	COG0768	penicillin binding
FR848_25065	COG1609	Transcriptional regulator
FR848_25075	COG0028	Belongs to the TPP enzyme family
FR848_25090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR848_25095	COG0473	3-isopropylmalate dehydrogenase activity
FR848_25115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FR848_25120	COG0738	Major facilitator superfamily
FR848_25130	COG0583	DNA-binding transcription factor activity
FR848_25135	COG2271	Major facilitator Superfamily
FR848_25140	COG2814	Major facilitator Superfamily
FR848_25160	COG4143	(ABC) transporter
FR848_25165	COG1178	ABC-type Fe3 transport system permease component
FR848_25175	COG0586	Pfam SNARE associated Golgi protein
FR848_25195	COG0235	Class ii aldolase
FR848_25200	COG0417	DNA replication proofreading
FR848_25210	COG0564	pseudouridine synthase activity
FR848_25220	COG3493	citrate carrier protein
FR848_25235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FR848_25340	COG0511	ligase activity, forming carbon-carbon bonds
FR848_25340	COG5016	pyruvate
FR848_25360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FR848_25370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FR848_25375	COG0471	metal ion transport
FR848_25380	COG0471	metal ion transport
FR848_25385	COG2828	Protein conserved in bacteria
FR848_25390	COG0583	DNA-binding transcription factor activity
FR848_25405	COG1047	Peptidyl-prolyl cis-trans
FR848_25420	COG0196	riboflavin kinase activity
FR848_25440	COG0583	DNA-binding transcription factor activity
FR848_25500	COG4735	regulation of single-species biofilm formation
FR848_25505	COG1584	GPR1 FUN34 yaaH family protein
FR848_25510	COG0477	Major facilitator Superfamily
FR848_25515	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR848_25525	COG1115	amino acid carrier protein
FR848_25535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FR848_25545	COG0527	aspartate kinase activity
FR848_25545	COG0460	homoserine dehydrogenase
FR848_25555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FR848_25565	COG0745	RESPONSE REGULATOR receiver
FR848_25570	COG4452	Inner membrane protein CreD
FR848_25575	COG2205	protein histidine kinase activity
FR848_25580	COG0745	RESPONSE REGULATOR receiver
FR848_25585	COG3045	CreA protein
FR848_25590	COG2207	Transcriptional regulator
FR848_25590	COG3708	Transcriptional regulator
FR848_25610	COG0741	lytic transglycosylase activity
FR848_25615	COG0488	(ABC) transporter
FR848_25625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FR848_25630	COG0560	Phosphoserine phosphatase
FR848_25645	COG0813	purine-nucleoside phosphorylase activity
FR848_25665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR848_25670	COG0084	hydrolase, TatD family'
FR848_25675	COG4667	esterase of the alpha-beta hydrolase superfamily
FR848_25680	COG5487	UPF0391 membrane protein
FR848_25685	COG2823	Periplasmic or secreted lipoprotein
FR848_25695	COG1011	Hydrolase
FR848_25700	COG0456	acetyltransferase
FR848_25705	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FR848_25735	COG3706	GGDEF domain
FR848_25740	COG4114	ferric iron reductase
FR848_25745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_25750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR848_25755	COG2197	response regulator
FR848_25760	COG2197	response regulator
FR848_25765	COG2207	Transcriptional regulator
FR848_25775	COG2966	Psort location CytoplasmicMembrane, score
FR848_25790	COG1484	DNA-dependent DNA replication
FR848_25805	COG5464	transposase or invertase
FR848_25815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR848_25820	COG3716	PTS system mannose fructose sorbose family IID component
FR848_25825	COG3715	PTS system
FR848_25840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FR848_25840	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FR848_25850	COG1063	alcohol dehydrogenase
FR848_25855	COG1802	Transcriptional regulator
FR848_25860	COG2271	Major facilitator Superfamily
FR848_25865	COG0456	acetyltransferase
FR848_25875	COG1737	Transcriptional regulator
FR848_25880	COG0800	Aldolase
FR848_25885	COG3734	2-keto-3-deoxy-galactonokinase
FR848_25890	COG4145	pantothenate transmembrane transporter activity
FR848_25900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FR848_25910	COG1846	Transcriptional regulator
FR848_25915	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR848_25925	COG1012	belongs to the aldehyde dehydrogenase family
FR848_25930	COG3384	dioxygenase
FR848_25940	COG3971	2-oxopent-4-enoate hydratase activity
FR848_25960	COG2368	4-hydroxyphenylacetate
FR848_25965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR848_25970	COG1966	Carbon starvation protein
FR848_25975	COG2879	small protein
FR848_25980	COG0523	cobalamin synthesis protein
FR848_25995	COG1012	belongs to the aldehyde dehydrogenase family
FR848_26010	COG1280	lysine exporter protein (LysE YggA)
FR848_26020	COG2733	membrane
FR848_26025	COG2814	Major facilitator Superfamily
FR848_26030	COG1475	DNA binding
FR848_26035	COG3969	phosphoadenosine phosphosulfate
FR848_26045	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FR848_26050	COG1924	4 iron, 4 sulfur cluster binding
FR848_26060	COG1473	amidohydrolase
FR848_26065	COG0700	Nucleoside recognition
FR848_26070	COG3366	ferrous iron transmembrane transporter activity
FR848_26075	COG0583	DNA-binding transcription factor activity
FR848_26085	COG1566	PFAM secretion protein HlyD family protein
FR848_26095	COG5457	Domain of unknown function (DUF1127)
FR848_26100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR848_26135	COG0531	amino acid
FR848_26160	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR848_26180	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_26185	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_26190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_26195	COG1454	alcohol dehydrogenase
FR848_26195	COG1012	belongs to the aldehyde dehydrogenase family
FR848_26210	COG1882	Formate acetyltransferase
FR848_26215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR848_26220	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FR848_26225	COG4869	propanediol catabolic process
FR848_26255	COG0814	amino acid
FR848_26265	COG3706	GGDEF domain
FR848_26270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_26275	COG0842	Transport permease protein
FR848_26275	COG1129	ABC transporter
FR848_26280	COG0842	Transport permease protein
FR848_26310	COG2850	peptidyl-arginine hydroxylation
FR848_26315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FR848_26330	COG0477	Major facilitator Superfamily
FR848_26340	COG0477	Major facilitator Superfamily
FR848_26345	COG4948	Mandelate Racemase Muconate Lactonizing
FR848_26350	COG1028	Short-chain dehydrogenase reductase Sdr
FR848_26355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR848_26395	COG1715	Restriction endonuclease
FR848_26410	COG1215	transferase activity, transferring glycosyl groups
FR848_26440	COG2003	Belongs to the UPF0758 family
FR848_26475	COG4735	regulation of single-species biofilm formation
FR848_26480	COG4983	Phage plasmid primase, P4 family domain protein
FR848_26520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FR848_26530	COG0582	viral genome integration into host DNA
FR848_26550	COG1064	alcohol dehydrogenase
FR848_26560	COG0395	ABC-type sugar transport system, permease component
FR848_26565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FR848_26570	COG3842	ATPase activity
FR848_26580	COG2814	Major facilitator Superfamily
FR848_26590	COG1082	Xylose isomerase domain protein TIM barrel
FR848_26600	COG3962	Belongs to the TPP enzyme family
FR848_26605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR848_26610	COG0837	glucose binding
FR848_26610	COG1737	Transcriptional regulator
FR848_26615	COG3718	enzyme involved in inositol metabolism
FR848_26630	COG0433	COG0433 Predicted ATPase
FR848_26635	COG0795	lipopolysaccharide-transporting ATPase activity
FR848_26640	COG0795	lipopolysaccharide-transporting ATPase activity
FR848_26650	COG2927	DNA polymerase III (CHI subunit)
FR848_26655	COG0525	valine-tRNA ligase activity
FR848_26675	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FR848_26680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FR848_26685	COG2731	YhcH YjgK YiaL family protein
FR848_26715	COG3397	chitin binding
FR848_26720	COG0251	oxidation-reduction process
FR848_26740	COG1263	PTS System
FR848_26740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR848_26745	COG0366	Alpha amylase catalytic
FR848_26750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR848_26755	COG1486	melibiose metabolic process
FR848_26775	COG0602	queuosine metabolic process
FR848_26780	COG3501	Rhs element vgr protein
FR848_26800	COG3711	transcriptional antiterminator
FR848_26800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR848_26805	COG2706	6-phosphogluconolactonase activity
FR848_26820	COG3964	amidohydrolase
FR848_26850	COG3783	Cytochrome b(562)
FR848_26855	COG0312	modulator of DNA gyrase
FR848_26865	COG1012	belongs to the aldehyde dehydrogenase family
FR848_26885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR848_26895	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_26900	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_26905	COG1129	ABC transporter
FR848_26910	COG1879	ABC-type sugar transport system periplasmic component
FR848_26915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FR848_26920	COG2105	PFAM AIG2 family protein
FR848_26925	COG2911	Protein conserved in bacteria
FR848_26930	COG0729	surface antigen
FR848_26940	COG1253	flavin adenine dinucleotide binding
FR848_26965	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FR848_26980	COG1733	regulation of RNA biosynthetic process
FR848_26985	COG0702	epimerase
FR848_26995	COG0697	spore germination
FR848_27005	COG1113	amino acid transport
FR848_27010	COG0545	Peptidyl-prolyl cis-trans isomerase
FR848_27020	COG3061	Opacity-associated protein A
FR848_27030	COG0359	binds to the 23S rRNA
FR848_27040	COG2965	DNA replication, synthesis of RNA primer
FR848_27080	COG3414	Phosphotransferase system galactitol-specific IIB component
FR848_27100	COG1073	alpha beta
FR848_27105	COG3650	response to hydrogen peroxide
FR848_27115	COG1960	acyl-CoA dehydrogenase activity
FR848_27125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR848_27130	COG0557	exoribonuclease II activity
FR848_27145	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FR848_27150	COG0330	HflC and HflK could
FR848_27155	COG0330	HflC and HflK could
FR848_27160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR848_27180	COG0860	N-Acetylmuramoyl-L-alanine amidase
FR848_27185	COG0802	atpase or kinase
FR848_27190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FR848_27190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FR848_27195	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FR848_27215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR848_27220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FR848_27235	COG3264	Mechanosensitive ion channel
FR848_27235	COG1511	domain protein
FR848_27240	COG0531	amino acid
FR848_27250	COG1053	succinate dehydrogenase
FR848_27255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR848_27270	COG3040	lipid binding
FR848_27275	COG2076	Multidrug Resistance protein
FR848_27295	COG1509	lysine 2,3-aminomutase activity
FR848_27310	COG3121	Chaperone
FR848_27350	COG0459	protein refolding
FR848_27360	COG0531	amino acid
FR848_27365	COG3030	protein affecting phage T7 exclusion by the F plasmid
FR848_27370	COG1027	Aspartate ammonia-lyase
FR848_27375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR848_27390	COG1309	transcriptional regulator
FR848_27405	COG1216	Glycosyl transferase, family 2
FR848_27420	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR848_27435	COG0861	Integral membrane protein TerC family
FR848_27460	COG2824	Alkylphosphonate utilization operon protein PhnA
FR848_27465	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FR848_27470	COG2188	Transcriptional regulator
FR848_27475	COG3624	Phosphonate C-P lyase system protein PhnG
FR848_27480	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FR848_27485	COG3626	phosphonate metabolism
FR848_27490	COG3627	carbon phosphorus lyase activity
FR848_27495	COG4107	phosphonate C-P lyase system protein PhnK
FR848_27500	COG4778	phosphonate C-P lyase system protein PhnL
FR848_27505	COG3454	Phosphonate metabolism
FR848_27510	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FR848_27515	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FR848_27525	COG0698	ribose 5-phosphate isomerase
FR848_27530	COG1737	Transcriptional regulator
FR848_27535	COG1879	ABC-type sugar transport system periplasmic component
FR848_27540	COG1129	ABC transporter
FR848_27545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR848_27550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR848_27555	COG1940	carbohydrate kinase activity
FR848_27565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FR848_27570	COG1301	dicarboxylic acid transport
FR848_27580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR848_27585	COG3162	membrane
FR848_27620	COG1346	cytolysis
FR848_27625	COG1380	Effector of murein hydrolase LrgA
FR848_27630	COG0583	DNA-binding transcription factor activity
FR848_27635	COG0025	NhaP-type Na H and K H
FR848_27640	COG2252	PERMEase
FR848_27650	COG0789	Transcriptional regulator
FR848_27660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FR848_27675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR848_27685	COG4771	TonB-dependent receptor
FR848_27690	COG0741	lytic transglycosylase activity
FR848_27695	COG0629	single-stranded DNA binding
FR848_27700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FR848_27715	COG2315	Protein conserved in bacteria
FR848_27720	COG0432	Pfam Uncharacterised protein family UPF0047
FR848_27730	COG1448	Aminotransferase
FR848_27735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR848_27740	COG0305	Participates in initiation and elongation during chromosome replication
FR848_27755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR848_27765	COG0735	belongs to the Fur family
FR848_27770	COG3237	CsbD-like
FR848_27775	COG0534	Mate efflux family protein
FR848_27785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR848_27855	COG0251	oxidation-reduction process
FR848_27865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FR848_27875	COG0527	aspartate kinase activity
FR848_27880	COG3541	Predicted nucleotidyltransferase
FR848_27895	COG4650	regulator
FR848_27910	COG1187	pseudouridine synthase activity
FR848_27950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FR848_28055	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR848_28085	COG0739	heme binding
FR848_28095	COG2132	Multicopper oxidase
FR848_28100	COG3667	copper resistance
FR848_28105	COG2372	response to copper ion
FR848_28110	COG1276	copper resistance
FR848_28115	COG0745	RESPONSE REGULATOR receiver
FR848_28120	COG2205	protein histidine kinase activity
FR848_28185	COG1620	l-lactate permease
FR848_28190	COG0277	FAD linked oxidase domain protein
FR848_28195	COG0247	lactate metabolic process
FR848_28200	COG1139	Iron-sulfur cluster binding protein
FR848_28205	COG1556	Lactate utilization protein
FR848_28210	COG2610	gluconate transmembrane transporter activity
FR848_28215	COG4680	protein conserved in bacteria
FR848_28265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FR848_28280	COG3316	Transposase and inactivated derivatives
FR848_28305	COG4584	PFAM Integrase catalytic
FR848_28310	COG1484	DNA-dependent DNA replication
FR848_28325	COG3039	Transposase
FR848_28375	COG2076	Multidrug Resistance protein
FR848_28385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FR848_28395	COG0589	response to stress
FR848_28400	COG0659	secondary active sulfate transmembrane transporter activity
FR848_28410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FR848_28425	COG3316	Transposase and inactivated derivatives
FR848_28460	COG3316	Transposase and inactivated derivatives
FR848_28465	COG3316	Transposase and inactivated derivatives
FR848_28480	COG1609	Transcriptional regulator
FR848_28490	COG2223	nitrite transmembrane transporter activity
FR848_28570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR848_28600	COG2188	Transcriptional regulator
FR848_28615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR848_28620	COG0318	PFAM AMP-dependent synthetase and ligase
FR848_28635	COG3677	Transposase
FR848_28650	COG4598	ABC transporter
FR848_28670	COG0583	DNA-binding transcription factor activity
FR848_28945	COG0629	single-stranded DNA binding
FR848_29070	COG1475	DNA binding
FR848_29075	COG1192	Involved in chromosome partitioning
FR848_29110	COG1461	Dihydroxyacetone kinase
FR848_29115	COG4372	Transposase
FR848_29120	COG3436	PFAM IS66 Orf2 family protein
FR848_29130	COG2376	Dihydroxyacetone kinase
FR848_29220	COG2801	Transposase and inactivated derivatives
FR848_29225	COG3547	Transposase (IS116 IS110 IS902 family)
FR848_29230	COG3111	PFAM Bacterial OB fold (BOF) protein
FR848_29245	COG2814	Major facilitator Superfamily
FR848_29295	COG3077	Addiction module antitoxin, RelB DinJ family
FR848_29400	COG3316	Transposase and inactivated derivatives
FR848_29425	COG3335	DDE superfamily endonuclease
FR848_29430	COG3335	DDE superfamily endonuclease
FR848_29445	COG3335	DDE superfamily endonuclease
FR848_29475	COG3316	Transposase and inactivated derivatives
FR848_29485	COG3978	acetolactate synthase activity
FR848_29490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR848_29500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR848_29510	COG3414	Phosphotransferase system galactitol-specific IIB component
FR848_29515	COG3775	system Galactitol-specific IIC component
FR848_29530	COG2376	Dihydroxyacetone kinase
FR848_29550	COG1461	Dihydroxyacetone kinase
FR848_29555	COG2376	Dihydroxyacetone kinase
FR848_29560	COG0583	DNA-binding transcription factor activity
FR848_29570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR848_29580	COG3316	Transposase and inactivated derivatives
FR848_29595	COG0747	negative chemotaxis
FR848_29600	COG0601	transmembrane transport
FR848_29605	COG0444	Belongs to the ABC transporter superfamily
FR848_29610	COG4608	Belongs to the ABC transporter superfamily
FR848_29615	COG2188	Transcriptional regulator
FR848_29620	COG1363	Peptidase, m42
FR848_29640	COG3316	Transposase and inactivated derivatives
FR848_29675	COG0789	Transcriptional regulator
FR848_29705	COG3344	reverse transcriptase
FR848_29850	COG0629	single-stranded DNA binding
FR848_30165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR848_30165	COG0426	domain, Protein
FR848_30285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR848_30330	COG3451	type IV secretory pathway VirB4
FR848_30395	COG3316	Transposase and inactivated derivatives
FR848_30405	COG3173	Aminoglycoside phosphotransferase
FR848_30430	COG3316	Transposase and inactivated derivatives
FR848_30440	COG1695	Transcriptional regulator