LOCUS MN166823 25624 bp DNA linear PHG 25-SEP-2019 DEFINITION Klebsiella phage ST512-KPC3phi13.5, complete genome. ACCESSION MN166823 VERSION MN166823.1 KEYWORDS . SOURCE Klebsiella phage ST512-KPC3phi13.5 ORGANISM Klebsiella phage ST512-KPC3phi13.5 Viruses; unclassified viruses; unclassified bacterial viruses. REFERENCE 1 (bases 1 to 25624) AUTHORS Bleriot,I., Guijarro,P., Trastoy,R., Blasco,L., Ambroa,A., Perez-Nadales,E., Fernandez-Cuenca,F., Torre-Cisneros,J., Oteo,J., Oliver,A., Canton,R., Kidd,T., Navarro,F., Miro,E., Pascual,A., Bou,G., Martinez-Martinez,L. and Tomas,M. TITLE Direct Submission JOURNAL Submitted (10-JUL-2019) Microbiologia, CHU A Coruna, As Xubias 84, A Coruna, A Coruna 15006, Spain COMMENT ##Assembly-Data-START## Assembly Method :: Velvet v. 1.2.10 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..25624 /organism="Klebsiella phage ST512-KPC3phi13.5" /mol_type="genomic DNA" /host="Klebsiella pneumoniae ST512-KPC3" /db_xref="taxon:2555916" misc_feature complement(1..207) /note="similar to phage protein DUF3277; coding region disrupted by phage integration" CDS complement(218..1363) /note="Phage protein DUF3383" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95161.1" /translation="MAQGLPVSNVVNVDVIMSPVAATGRNFGALLILGTSTVIPVTER IRQYSAIEDIGDDFGADSPEYEAATIFFSQSPKPTLVYIGRWAKTLAEGEAGAVETLL QAVNACLQYTNWYGLAIADSADLVEADVISVAAAIEASSLSRILAVTTADVNVLVSGN TDNIGYKLKAAGYSRTFWQYSSSSKYAAISAFGRAFTVNFTGNNTTITLKFKTEPGVT HETLTTAQASAIDAINGNVYVYYANDTAIIQQGVMANGDFFDERHGLDWLQNYVQTNL YNLLYTSATKIPQTDAGVTRLMTNVEASLDQAVNNGLIAPGVWNGGPIGQIESGDTLT KGYYVYADAVANQAQSDREARKSPVIQAAIKLAGAIHYGDVQINVVR" CDS complement(1367..1909) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95162.1" /translation="MSNDSTTAGYLTPVGDSPPYDEDLERLISRWIRGVTGLAATLVY PRWTDPQKQIPKNGTTWCAFGITGIQEDFNPAYVQGEENTEQWSHETVSLILCFYGPQ GLAMATRFRDGLLVSQNNDELNRSGLTFLQHGRILNLPELINNQWVRRYDISVDLRRK IIRQYGIQSLVDAPVQFFGD" CDS complement(1902..2288) /codon_start=1 /transl_table=11 /product="head tail adaptor" /protein_id="QEQ95163.1" /translation="MPFLDVTDVLLDPDFVDLSLVCYRQVQTVDEDNFPTNTVQAIPF SGVVTVDRSLEAKRMAAGQNINGAILIVTQFRLTQGQPGLDADIVTYRGRDYRVTFVD PYTAYGAGFVQAHCELLEFDGGTPIE" CDS complement(2288..2794) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95164.1" /translation="MKSGLTIREDNYSSVLDALKQLSGTDVLVGIPAGPPRDDAPLSN AELGYLQSTGATVEIDGETVTLPPRPFLDMGIEDSRDKTTERLKLAAQSALEGKADVA SMHLEAAGQIARDASKAVIEAGDRLTPLSEKTIKKRREMKPPIPGDKPLRARGFLFRA IQYVVRKE" CDS complement(2791..3210) /note="Phage protein DUF4054" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95165.1" /translation="MARNQSLPTPEQFRATFPQFADDTKYPTPMIQARLNLADAMLSE SRFGVDIFPYIVGLYVAHYMYLYAADMRGVAVGTAGGINSGIQTAKSVDKVSASYDAS ATLDPNAGFWNNSRYGSEFWEYLMMFGAGAVQLGTPE" CDS complement(3500..4441) /note="Hypothetical protein DUF2184" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95166.1" /translation="MPMTFDQATVDGTGAFLVHELERLDQTLNLPLVNFTWSRDIQLR EDVSIADEISSFTNTTFAAAGTPNANGKNWLSKAATAMAGLNVDIAKTGFPLTLWGME LGWTVPELQAAAQVGRPIDTQKYDGMQLKWNMDTDEQVYIGDSGLNVKGLLNLTQVTP TNAAKTWATSTADEIRASINAGLSAAWANSAYSMVPTDMLIPPEQFSLLASTIVSSAG NQSLLTYLETNTIAYHQNGRPLNIRPVKWAKGRGVSNSDRMMFYTNDKKYVRFPMVPL MSVPIQYRGLYQLVTYYGKLGAVEPVYPETLAYVDGI" CDS complement(4453..4947) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95167.1" /translation="MGNTFLYRMPAGIAGAISRPQDLTVEPQLLDSSNLFPAYGLGGK ISSGKFVPIAASDTASVLVGIYVRPYPTASQPDKVQQVGSGKNFTGDCLVRGYVTVNI GADASSVALHGPVYMRVATPSASSPLGAFLAAADGSNTVQITNAYFNGPGDTSGNIEL AFNI" CDS complement(4951..6153) /note="Phage protein DUF2213" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95168.1" /translation="MKYFFKTRLGNTRFQLADGSVLFKDVPIARTGEQEYDATERPEL VPNDRGKVIVRRMPEEVFSERAMASFEGMAVTIGHPRDFDGQIIFVTPDNWRQLAHGH IQNVRRGTDDKIDLLLADVIVKTPEALQAIDDGDDEVSCGYDADYEQISPGLAKQSAI TANHLALVPNGRAGFRCAIGDSMPSTTKNWFTRLLKARKTGDAAEMASLIDNPPDDVT GDNDVSTSMTPGGVVINLAPQNPLPGPALPGTGDGEEEIPAWGKALIEAVAKLTPAAA APGTGDAEDEEEKKEEEGKVTGDAAYRADLIQPGIQLPEKAKPTAFKRQVLASADQSL VRSIVGDADISKLKKATVDMAFTAVSELAKNRNTKTVDSLQTQTATTVKTIAGMNQAA QEFWSKRG" CDS complement(6205..6753) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95169.1" /translation="MVGRKMFAQVEREEWNQWRSVSEEISAGLRDVIGNTPVGMVAQD IVYRQIRYMKSLPLEAAGRVREIQERAIQAVIHGERPDQLYEMIMQSGDVAASRARMI ARTEIGRATGALTQARALAVGSEGYWWRIEGAGTRPSHRKMKDKFVRWDSPPTLDGMT GHAGCLPNCKCWSEVQIPDPVK" CDS complement(6809..8260) /note="Phage protein DUF1073" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95170.1" /translation="MAKKTGRVATADSYDNFVARVGMQQPNQHAASTYRANYTSRNRL LIEWAYRSSWIIGAAVDSKADDMTKKGVRITSEIDPKRRGILESRFDELQLWDCINET LKWSRLYGGAVALILIEGQAPLTPLVLDKVGKGSFKGLAVLDRWMINPQLTRRIKALG PNLGKPEFYDIVTTAQGLPAWTVHHSRLIRMDGVKLPYQQKITENEWGMSIVERIFDR LTSYDSTSVGAAQLAYKAHLRTAKIKKLREIIATGGKAFEALIKNMEMVRQYQTNEGM SLFDSEDEFETHSYSFAGLSDLLSEFKEDIAGAVGIPLVRLFRQSPKGFSTGDADLAN YYDDVGALQERDLRPHIRLLFDVLHRSEFGEPLPQDFTFEFNPLWQMSDTDRSTVATN TTTALATAVRDLGMSPAAALTDLRELSDVTGIGASISDEDIQNAAKQWQETESETSPP PPIGGPVSEKPTGDSRPDKSNRHGFLRWFTGKR" CDS complement(8498..9898) /codon_start=1 /transl_table=11 /product="terminase large subunit" /protein_id="QEQ95171.1" /translation="MTSTLTSKPTLNPVLRSFWTTQARNKVLYGGRSSSKSWDAAGIA IFLSNKYSLRFCCARQIQNKIEESVYTLLKIQIDRFGLRHRFRILNNKIINRVTGSEF VFYGLWRNIEEIKSLEGISVLWLEEAHALTEYQWKILEPTIRKEGSECWFIFNPGLVT DFVWRNFVVDPPEDTLIRKINYDENPFLSDTMLKVIEAAKRRDPDGFKHVYEGVPESD DDAAIIKLSWIEAAVDAHKILNFEPSGRKRIGFDVADSGADKCANVYRHGSVVYWADE WKAKEDELLKSCQRTYQAALERDADIVYDSIGVGASAGAKFSEINEDRKRENMNASRI NYQRFNAGAGVNEPDYEYSGIPNKDFFANLKAQAWWLVADRFRNTFNAVKNGEQYPVD ELISIDSSCPLLEKLKLELTTPHRDFDKNGRVMVESKKDLAKRDVPSPNVADAFIMAF APTDTAMDIWEALGNS" CDS complement(9849..10601) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95172.1" /translation="MATPDWEAIESAYRAGVLSLRDIGDKYGVTEGAIRKRAKKFDWV RKASTQVRKNGTQKSKARTSEKPASSGRTQPKAEPPPDTKPIRGVRTDPPTNPFQPGN QQALKHGGYARRLLLKDEVIEDAKALTLEDELFRLRANNLVAAENIGRWLTKLDDAEG DQERKVLMENISAAEKAMMRNTVRIESIVGTLATVGKIFADTDYRKAATDKVSLEADR LRRDAGIDDGNGERDLNDFYSDIQTDAESGPA" CDS complement(10703..11059) /note="negative regulator GrlR" /codon_start=1 /transl_table=11 /product="negative regulator" /protein_id="QEQ95173.1" /translation="MPLPIGYNIRCDMKNGIYFVTFSSNNHDVGQGTVVVKDNAINGG DFGFTYQGHIQGDTLDLHVSQHNPQAVNVIQGVNDYTMEMSIVEVQGGYLLSGAVKGI PQARLRVSAKFIGELV" CDS complement(11116..11229) /codon_start=1 /transl_table=11 /product="Rz1 lytic protein" /protein_id="QEQ95174.1" /translation="MTWGQSLDLNVSLLSALGQCNRDKADIRRSEIFRGKN" CDS complement(11258..11647) /codon_start=1 /transl_table=11 /product="lipase chaperone" /protein_id="QEQ95175.1" /translation="MSRLAAIISAVVICLMVCLGWLVMHYHNAAAEQKTRADGAEQQV NSTQAITANVLTTMTIFNSIAEANKNAKEQIALDASGAAADIKVAVANDDCAPAGIPA GAVKRLQQYKDSLRHRSGSAATLQPDS" CDS complement(11644..12174) /EC_number="3.2.1.17" /codon_start=1 /transl_table=11 /product="lysozyme" /protein_id="QEQ95176.1" /translation="MANLKTKLSSAMLALIAAGASAPVLMDQFLNEKEGKSLTSYRDG AGIWTICRGVTQVDGRPVTQGMKLTQAKCDQVNAVERNKALAWVDQNVRVPLTPPQKV GIASFCPYNIGPGKCFPSTFYRKLNAGDRKGACAEIRRWIFDGGKDCRVRSNNCYGQV SRRDQESALACWGIDE" CDS complement(12177..12425) /codon_start=1 /transl_table=11 /product="holin" /protein_id="QEQ95177.1" /translation="MKMPDKIFSAASYCSSGGLICTGLARTYDWFHGLDWNFIALASG VIIGVATYLTNLYFKRRWTKMYQQSLDRGYGGPPPQDE" CDS 12452..12571 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95178.1" /translation="MLSVVSKRFRAVGLDLTTKRVDDDSREPEMKKATQMRSL" CDS complement(12609..12764) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95179.1" /translation="MLSIVGYNARTKLKHETSLRRVFLFLATEKLADWKTSIEAALWM GALSKAG" CDS complement(12831..13613) /note="Phage antitermination protein @ Phage antitermination protein Q" /codon_start=1 /transl_table=11 /product="antitermination protein" /protein_id="QEQ95180.1" /translation="MKLEASLKHFSPQGMHITDDAKSTSPNRLNGTDIMTGIGVTSSR ARFGLAAFFGKAGISKTDEQLAIQALAQFAIKNAPKNVRKAAGDKLGTCMLTLAQFAF AEYSRSAATSATCHSCSGTGFISSHEDVIKHPGIFDADGVEVKAPKIRNELVKRVCGV CGGKKVIHARCRCGGKGEVLDRKATKELGAPVFKTCERCSGNGFSVVPSATVHRAILK RLPDLHQSSWSRNWKPFYEGLVDMLRQGERQAAVEFEKATSY" CDS complement(13610..14086) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95181.1" /translation="MMNNNNLQHNQFFTIEQDFSPEKITDAERLVMERFSHIYANWAD EKNLSREAEELRVREIKGFKNILLSPWTLSDVTIEWDYWESVLRHRYKTQNGDGYVQI IWDRRGWLTDLLCAMKPVTRAEALTVCKWLLACDYFEERDSLFDRIILNLVGECEE" CDS complement(14083..15045) /codon_start=1 /transl_table=11 /product="DNA primase" /protein_id="QEQ95182.1" /translation="MKTAEAAKGRWSEIFEYYGLPPITGKNHYKGECPVCKARGKYRV DDRDGQGTWICVCGSGDGMKLLTLTQSKSFSAICAEVDQLIGNNYQRINVPSNSSAAR QRQRVISKFSKLLDLRGTSAAGYLLQRGISRLPAEGIRFCDRQRHAGRVYQALYALAT DDKAELCYLHQTLLDGDRKADIDSAKRLKSLQEDSYLDHARSVAIRMFPVSTTIGIAE GIETALSCYQVYGVNTWAVINSGFMKKFRVPAGVKHLIIFADMDKHSATGHAAAFECA HANLLAKNDLVKVSIRWPDNGDFNDMLMNGDQVREQVFYKKVAA" CDS complement(15047..16624) /codon_start=1 /transl_table=11 /product="DEAD/DEAH box helicase" /protein_id="QEQ95183.1" /translation="MVYAPTGSGKTGLAAFIAAGLVSRGMRVLFVAPYTILINQTAQR FTEYGLPEDQISFIWRDHPNYDPNLLIQIASADTLIRREFPKNIDLLIVDEAHLRKRR ILKEIERITAEKKAKVIGLSGTPFAPFLGHYYQHLIKPTTIGELIQRGDLSKYEFFAP TKPDLSGVETKPSIEFGTDYDESQLAEIMCGSDLVGDIVDNWLRHGRDLPTVAFCVNK AHANFVTMQFNKAGINAEVMVAETPHEERQAMIHRFETGATKIIVSVGVLVAGFDSDV RCIIYARPTKSEIRWLQALGRGLRTAPGKDACLIFDHSGTVHRLGFPDSIEYDDLPST NDGMKAAAAGATKEREEKLPKECPECHFMKPSGVYVCPKCGFKPLVGQDVETDGTRNI KKMSKHETVYTKSDKQSWWSQIKFYQRHRAAQGKPVSDGWCAHTFQEKFGEWPNGLSD FPMEITPEVSNHIKHKLIKFAKRRERLQQMGKKPDQDLFPPPSASINYEPPEGSDGQL IIEAKRKLQKNVNSASQ" CDS 16837..17223 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95184.1" /translation="MYLSVGKGRYSCPNSQLPPTPLFPLPHPMYSQAGTKNKKQSRIV PCYHPAPLSPVTNGSLLRSGQGWLGRIPLQCASVCIHESAKPHIGFMPCPVLLAVWNG LGFERFLIHSCITLNGFLSCCWRQAQ" CDS complement(17282..17503) /codon_start=1 /transl_table=11 /product="XRE family transcriptional regulator" /protein_id="QEQ95185.1" /translation="MSGIKSLRRKAKVTQGELAALIDSSQGAVSHYETGRRIPDVAVG KRIVSAFKQLGLNTSLDEVFSDDVARDEA" CDS 17601..18269 /codon_start=1 /transl_table=11 /product="LexA family transcriptional regulator" /protein_id="QEQ95186.1" /translation="MAMKQRWQDLAKTRMKEVGMTQEQLAEALGITQGGLGHWLNARR EPNLEVIAKIFNILKMPGFVVNADGTISDSRADHNVSFNSINESKGSYPVISWVSAGD WMEAVEPYHRRAIDRWYDTTVECSEDSFWLDVRGDSMTSPAGLSIPEGMAILVDPQVE AINGKLVVAKLDGDNEATFKKLVIDAGQRFLKPLNPQYPIIPINGNCRIIGVVVDAKI TNLP" CDS complement(18389..18586) /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95187.1" /translation="MIDGLQNRYCFCIAISSNFVEINVLTLLFIGRETVIRYSYQLKK FLCTHLLHSINPLMHKQYITY" CDS 18602..18754 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95188.1" /translation="MSEAEEKRLNKDKIMMLSSVVADLAELAIATNKIANSATYSSGY KDAKNV" CDS 18747..18935 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95189.1" /translation="MSDITLQKAASKAYQAEIVARMLENYPHKLTDSDVESVASLLAD LIGPVAAYLIEEESKNPA" CDS 19004..19102 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95190.1" /translation="MINKQAFKTAQLFVSLGYWSIAMLYLKKAYGK" CDS 19105..19470 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95191.1" /translation="MNNLISTYRRRILKAALLRHQRKTGSSLLVIKLNKGGISTIELT EILLDGLLRKFERLALGEYGNVEGVKALKGIYSNSVDVNGSGEFLTESGKELIDELIS ELVEFVKKQKPVTAESGNE" CDS 19463..19717 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95192.1" /translation="MNNQQTMLYQGVLIPRPVLNVDLHVLPDFTGRVVLHIENGRVIC DRQLFDDEHICTLATFIEMARDAGLRIEEEAGGTDSDTNS" CDS 19785..19907 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95193.1" /translation="MRRTGYLSLKVNPRWRLLSKDDGRNWEVMSHETYNREKDK" CDS 19904..20329 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95194.1" /translation="MIDNRTVSAIDLALQKHPTPVGDLFAAIRHGRMKRCFSRDTAIR YLAFFMTSRAFGRSGFKQRYPDVQVIHPLNPELSSWQRGAVTTEYFNAHQRTVRRLRR ILARKREMQKWCKKWDAMHDRYVKEREELQACKPGGLSR" CDS 20326..20520 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95195.1" /translation="MIAYLRIVLSVVIVASVYGLFVPILISMKDTTAVISGFALAILT PPCIYAICKGLVLTVTKEKK" CDS 20517..21344 /codon_start=1 /transl_table=11 /product="serine protease" /protein_id="QEQ95196.1" /translation="MKKAIMASIIALSAIGLVGCDRVEPGNVGIKVNKLGDDKGVGEV VGVGRYWTGWNTEVYIFPTFKQMKTYEDAFNFQMSDGTTIGYHIGVAYKVDPTKVTTV FQTYRKGVDDITDTDLRQKIADALNRLASRMSTDKFIDGGKAELLENALKEIQSDMGP VGIQVISLSYVGRPEYPPTVIESINAKVTANQKTLQREQEVKQREAEANMLRAEADGQ ADAKLKLAEAEAKSIQIRGQALRENPEVLQLEAINKWNGTLPQYMTSGTNTPFIQVK" CDS 21341..21967 /codon_start=1 /transl_table=11 /product="2-polyprenylphenol hydrolase related flavodoxin oxidoreductase" /protein_id="QEQ95197.1" /translation="MIHQPGDKPGTYERFAMLQNMLNPEPTSTGIRSGNRVIGYSAAI RLLDNGRYDKHLADGMEILACIMEAVESNWITLNIEKELILWRWLLAAVFITEELEKN GTVDVPNDTGGVDTAVIYSSKHGAISVYPGPERFALANHIELGAIEKYGPEVGQQLAL RMYQDMVIADEEFGFRLSALGREGLNLLHDSFIEHIQIEGVPEAPIMH" CDS 21976..22683 /note="antirepressor family protein Rha" /codon_start=1 /transl_table=11 /product="antirepressor family protein" /protein_id="QEQ95198.1" /translation="MMNNLITNKPSMTSLEIAELVEKRHDNVKRTIETLIMRGVITSP QIEEKPTAGRPTTIYVFESEEGKRDSIIVVAQLSPEFTARLVDRWKELEEERSRPKSQ AELIAEMALLNVEQERRLYQVEEQVETVVEAVENIKRGNMRAGYVGYRQVVAKSGMTD AKCRNLVNAYRIPTDTHEFMTPDGLLSRRAIVEFEPFMKAFRQMMAEAEPRGTRWYHP KMGLFQAIGWEEKHCEN" CDS 22673..22897 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95199.1" /translation="MKIEFNDQGSVSVITVTSTVFEFRRHNRAIDVALFLTPEITSQS SGFFIMKTILSGKTHHALRAYKHLIREAKQ" CDS 22894..23106 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95200.1" /translation="MRNGQHYAYPNPSNATPGGMTYRQYLIAKIAPVMITNFFSNDAW TDYDDLARTLMMAVDAIIEAEQETAE" CDS 23103..23582 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95201.1" /translation="MTICEKRLKRIAGGEPFFPGEVVAMALELLANSKETLRPEYPET LPCPVILEPGFRFGKGVGTHLVLRALNNRAKRYAELDAMGPEARAEHDAAIVELREKL GFGTQAKTAVQVKLPGLPQLGSNAEWYQGFAAGAGSMREACAAALISAGIEIIGETM" CDS 23655..23801 /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QEQ95202.1" /translation="MNREFEIWIRLRYGGRYDLTRDGHGYYSREVVKRMYEVWCHCRG LEVV" CDS complement(23984..25165) /note="Integrase - DUF4102" /codon_start=1 /transl_table=11 /product="integrase" /protein_id="QEQ95203.1" /translation="MAISDTKLRSIYGKPYSGPAEITDSDGLGVRITPKGVISFQFRF RWEGKQNRMGLGRYPALTLRDARNIVADLRESADKGIDPRTLAGGNKSKSKPTVKDCL DYWKENYVDVTLRAKTIALYKSTVIKHMRDAFPGIPVEDIPVRLWVERFTEEEKINPR RARHLLIQLRSAIGWCTRRQFVSTTELMLLQPKDIGVKPVIGETTLSYNQLAKIWMAI ERSRGSTSNRLLHQLLMLYGARNSELRLAIRGEFDREEGLWVVPAEKSKTNKIIRRPI FSAADDLLKKAEMTYGDILFPGEDLKSPITISGANKFLRRIKDSLGFGEFTSHDFRRT LATRLSEEGVAPHVIEKMLGHELGGVLSVYNKHDWIAEQKDAYDLYAEKIFWHIRKIS G" misc_feature 25422..25622 /note="similar to protease; coding region disrupted by phage integration" ORIGIN 1 aaaaaaactt gaccacaaca tgccgctctt accggcgtga aggctgtgca tcacttcccc 61 gtcggcgcct acggtcatgg tgttttttgc ctctgccatg actacggtga tcccctcttc 121 ggagttcgcc gagccgtaac ccagatcgat actgccggtc gggcccgtca gggatgcaga 181 gacgtcaata aaagagtaag tagacattta gttcccctta acggaccacg ttgatctgca 241 cgtcgccata atgaatagcg ccagccagct tgatcgccgc ctgaattacc ggcgacttac 301 gcgcttccct gtcggattga gcctggttag ctaccgcgtc ggcgtagacg tagtaaccct 361 tggtcagggt atccccggat tcaatctggc caatcgggcc accgttccag acacccggag 421 caatgaggcc gttatttacc gcctgatcca gtgaggcttc gacgttggtc attaaccggg 481 ttacgcctgc gtcggtctgc gggattttgg tggccgaggt gtaaagcagg ttatagagat 541 tggtctgaac gtagttctgc agccagtcca ggccatgccg ctcatcaaag aaatcaccgt 601 tcgccatcac accctgctgg ataatcgctg tatcgttggc gtagtagacg tagacgttac 661 cgttaatagc atcaatagcg gacgcctgtg cggtcgtcag cgtttcgtgc gtcacgcccg 721 gctcggtttt gaacttcagg gtgatcgtgg tgttgttgcc ggtgaaattc accgtaaacg 781 cacggccaaa tgccgagata gcggcgtatt tgctgctgga gctgtactgc cagaacgtac 841 ggctgtagcc ggcggctttc agcttatagc cgatgttgtc ggtattcccc gagaccagca 901 cattcacatc agcagtggta acggccagaa tgcggcttaa gctggatgcc tcaatagcag 961 cagcaacgga aatcacgtca gcctcaacca gatcggcgct gtcggcaatt gccagcccgt 1021 accagttggt atactgaagg caggcattaa cggcctgtag caaggtttcc accgccccgg 1081 cctctccttc cgccagcgtc ttcgcccaac ggccgatata gaccagcgtg ggttttggtg 1141 attgtgaaaa gaagatggtc gctgcttcgt attccgggga gtcagcgcca aaatcatcgc 1201 cgatatcttc aatggccgaa tactggcgaa tgcgctcggt aaccggaata acggtagagg 1261 ttcccagaat gaggagcgca ccgaagtttc gccccgttgc cgctaccggt gacatgatga 1321 cgtcaacgtt aacgacattg gaaacaggta agccctgtgc catgttttaa tctccaaaaa 1381 attgcactgg cgcgtcgacc agcgattgaa tgccgtactg gcggatgatt ttgcggcgca 1441 ggtcaacgct gatatcgtac cggcgcaccc actggttatt gatgagttcg ggcagattga 1501 ggatccgccc atgctgcaga aatgtcaggc cagagcggtt gagctcgtca ttgttctgcg 1561 agaccagcag accgtcacga aagcgcgtgg ccattgccag cccctgcggg ccatagaagc 1621 acaagatcag gctcacggtc tcatgcgacc actgttcggt gttctcttcg ccctgcacgt 1681 acgccgggtt gaagtcctcc tgaatgccgg tgataccgaa cgcgcaccag gtggtgccgt 1741 ttttgggtat ctgcttttgc gggtcagtcc agcgtgggta aaccagcgtg gcagccagcc 1801 ctgtcacacc ccgtatccag cggctgatta gccgttccag atcctcatcg tagggcggtg 1861 aatcaccgac gggggtcaga tatcccgccg ttgtgctgtc gttactcaat tggcgttccc 1921 ccgtcgaatt ccagaagctc gcaatgcgcc tgaacgaacc cggcaccgta cgccgtatac 1981 gggtcgacaa acgtcacacg ataatctcgc ccgcggtagg ttacgatatc ggcatctaat 2041 ccgggttgcc cctgagtcag cctgaactgc gtcacgatga gaatggcccc gttgatgttc 2101 tgtccggcgg ccatacgctt cgcttccagt gaacggtcga cggttacgac accagagaac 2161 ggaatagcct gcacggtatt ggttggaaaa ttatcttcgt ccactgtctg cacctgtcga 2221 taacacacca gagacaggtc gacaaagtcc ggatcaagca gaacatccgt cacatcgaga 2281 aacggcatta ttctttcctc acgacatact gaatcgctct gaacaggaat ccgcgggcac 2341 gcaacggctt atcgcctgga atgggaggct tcatttctct gcgcttcttg atggtttttt 2401 cagatagtgg ggtcagacga tcgcctgcct caatgacagc ctttgaggca tcacgcgcaa 2461 tctggcctgc ggcttcaaga tgcatcgacg ccacatctgc cttaccttca agcgcagact 2521 gagcggccag ctttaaacgc tctgtcgttt tatcccggga atcctcaata cccatgtcca 2581 gaaatggcct tggcggcaga gtaacggtct caccgtctat ctctacggtt gccccggtgg 2641 actggagata ccccagctca gcgttgctca gcggcgcatc atcgcgcgga ggacctgccg 2701 ggataccaac cagcacatca gtgcctgaca gctgcttcag cgcatccaga acgctgctgt 2761 aattgtcttc ccgaattgtg agcccgcttt tcattccggc gtccccagtt gaaccgcacc 2821 ggcaccaaac atcatcaggt attcccagaa ctccgatccg taacgggagt tgttccagaa 2881 accggcatta gggtccaggg ttgcgcttgc gtcataactg gctgaaacct tatccactga 2941 tttcgcggtc tgtatgccgc tatttatgcc accagcagta cccacagcta caccacgcat 3001 atcggcggcg taaaggtaca tgtagtgcgc aacatacagc ccgacgatgt agggaaagat 3061 atccacgcca aagcgcgact cactcagcat ggcatcagca agattcagtc gagcctgaat 3121 cattggcgtg gggtactttg tatcgtcagc gaactgcgga aaggttgccc tgaactgctc 3181 aggcgtcggc agactttgat ttcttgccat tattggtagt ctccggcaat tgcgcttcga 3241 gttcagcaat acgcgcgtct ttctcggcga tttttgcttc cagctcagca atgcgcgggt 3301 cttctgcgac cgctggcgct tcgccatccg gagaacagtg cgcttttacg aaccagtgat 3361 cagcaaccgt gtcatcgacg tcgtggaagc caaccgggaa atgcttttgc tctttgccgt 3421 cgttgaagtt aaacggggag agtacgtaaa tctttttcat tgcaagtcct catgagcggc 3481 cctttcgggc cgccgcaggt tagatgccgt cgacgtaggc cagagtttcc ggataaaccg 3541 gctctactgc acccagcttg ccgtaatagg ttacgagctg atacaggccg cgatactgga 3601 tcggcacgct catcagcgga accatcggga agcgaacgta tttcttgtcg ttggtgtaga 3661 acatcatgcg atcagagttc gacacgccac gacctttcgc ccatttcacc ggacggatgt 3721 tcagaggacg cccgttctgg tggtatgcga tggtgttggt ttccagatag gtcagcaggg 3781 actggttacc agcgctggat acgatggtgc ttgccagcag agagaactgc tccggcggga 3841 tcagcatgtc cgtcggtacc atggagtaag ctgagttggc ccacgcagca ctcaacccgg 3901 cattaatgct cgcccggatt tcgtcagcgg tggaggtcgc ccaggtcttc gcggcgttgg 3961 tcggcgttac ctgcgtcagg ttcagcaggc ctttaacgtt cagaccggaa tcgccgatat 4021 aaacctgctc gtccgtgtcc atgttccact tcagctgcat gccgtcgtac ttctgcgtgt 4081 cgatcgggcg accaacctgc gcagctgcct gcaattcagg aacggtccag ccaagctcca 4141 taccccacag tgtgagcggg aagccagttt ttgcgatgtc gacgttaagt ccagccatcg 4201 cggtcgcggc tttgctaagc cagtttttac cgttagcatt cggcgtaccg gcagcagcaa 4261 aagtggtgtt agtgaacgag ctgatctcat cagcaataga cacgtcttca cgcaactgga 4321 tatcgcgcga ccaggtgaaa ttcaccagcg gcagattcag tgtctgatcg agacgctcca 4381 gctcatggac aagaaaggca ccagtgccgt cgactgtcgc ctggtcaaat gtcattggca 4441 tttgcgattt ccttaaatat tgaaggccag ctcaatgttg ccgctggtgt cgccagggcc 4501 attgaagtaa gcgttagtga tctggacggt attcgagcca tcagcggcgg caaggaacgc 4561 gccgagaggg cttgaggcgg atggtgtggc cactcgcatg tagaccgggc catgcagagc 4621 aacgctggat gcatccgcgc cgatgtttac cgtgacgtaa ccacgtacca ggcaatcgcc 4681 ggtgaagttt ttaccgctgc ctacctgctg gactttatcc ggctggctgg cggtcggata 4741 cggacgaaca taaatgccca ccagcaccga cgctgtatcg ctcgcagcga ttggcacaaa 4801 tttcccggag gaaatcttgc cgccaaggcc gtaagcgggg aaaaggttgg aggagtccag 4861 cagttgaggt tcaaccgtca gatcctgcgg acgagaaatt gccccggcga tgcccgctgg 4921 catccggtaa agaaatgtat tacccattag ttagcctcgt ttagaccaga attcctgcgc 4981 ggcctgattc ataccggcaa tggttttaac agtggtggca gtctgcgttt gcaggctgtc 5041 gacggttttg gtattgcggt ttttcgccag ctcagaaaca gccgtgaaag ccatatctac 5101 cgtggctttt ttcagcttgc tgatatcggc atcaccgaca atagagcgaa ccagagattg 5161 atcggcagag gcaagcacct ggcgcttgaa tgctgtcggc ttcgcctttt ctggcaactg 5221 gatgcctggc tgaatcagat cggcacgata agcggcatcg ccggtaacct taccctcctc 5281 ttcctttttc tcctcttcat cctcggcatc gccggtacca ggagcagctg ccgcaggcgt 5341 gagtttggcc accgcctcaa tcagcgcctt accccatgca ggaatttctt cctcaccatc 5401 gccagtacca ggcaatgccg ggccgggaag cggattttgc ggtgcaaggt tgatgaccac 5461 tccgccgggt gtcatagagg tcgatacatc gttatcgccc gtgacatcat caggcgggtt 5521 atcaatgaga cttgccattt cggcagcgtc cccggtttta cgggccttca ggagccgggt 5581 aaaccagttt ttagtagtgc ttggcataga atcccctatt gcacaacgga aaccggcccg 5641 cccgttaggg acaagggcca gatggttagc ggtaatcgca gattgctttg cgagaccagg 5701 tgaaatctgt tcgtaatcgg cgtcgtaccc gcagctgacc tcgtcatcac catcatcaat 5761 ggcctgcagg gcttccgggg ttttgacgat gacatcagcc agcagcagat cgattttatc 5821 gtccgtgcca cgtcgtacgt tctggatgtg cccgtgagcc agctggcgcc agttatcagg 5881 ggtaacaaag atgatctgcc cgtcaaaatc tcgcggatgg ccgatagtga ctgccattcc 5941 ttcgaatgac gccatggctc gctcgctgaa cacctcttct ggcatccggc gtacgatgac 6001 cttccctctg tcgtttggga caagctcagg ccgctctgtg gcgtcgtact cctgctcacc 6061 agtccttgcg atcgggacgt ccttaaacag gacagaccca tcagcaagtt gaaagcgggt 6121 attacccagg cgggttttaa agaaatattt catgggttac ctgctgaatt gcgggcattg 6181 aaaaggccgc tcattggcgg cctgttattt tacagggtca ggtatttgca cttccgacca 6241 acacttgcag ttaggcaggc acccggcgtg tccagtcatg ccatcgagcg ttggcgggct 6301 atcccagcgc acaaacttat ctttcatttt tcggtgtgag ggcctggtgc ctgcaccttc 6361 aatgcgccac cagtatccct ctgatccaac tgccagagcc cgtgcctggg tcagtgcgcc 6421 agttgcgcgc cctatctctg tgcgggctat catccgcgcc ctgctggccg ccacgtcacc 6481 ggattgcatg atcatctcgt aaagctgatc ggggcgctca ccatggatga cagcctgtat 6541 cgcacgctcc tgaatttccc tgacacgtcc ggccgcctct aatggcagag acttcatgta 6601 gcgaatctgt cggtaaacga tgtcttgcgc caccatgccg acaggagtgt taccaatcac 6661 gtcacgcaga ccagcggata tttcttccga aacagagcgc cactgattcc actcttcacg 6721 ctccacctgg gcaaacatct ttcgaccgac catttcggcc cagtcgtcga tcaccccgga 6781 gtagtcaaca agcgatttag caatgctctc agcgcttgcc tgtgaaccat cgtaggaacc 6841 cgtgacgatt tgatttatct ggtcgactat cgccagtagg cttttctgat actggacctc 6901 cgatcggcgg cggagggctg gtttcagatt cagtctcctg ccactgtttc gccgcattct 6961 ggatatcctc atcgctaatt gaagcaccga tgccggtaac gtcagacagc tcgcgcaaat 7021 cagtcagagc agcagccggc gacatgccca aatcacgcac cgcggttgca agagcggtag 7081 ttgtgttggt tgccaccgtg gagcgatcgg tgtcgctcat ctgccacagg gggttaaact 7141 caaaggtgaa atcttgcggc aacggctcgc caaactctga gcgatgcagt acatcgaata 7201 acaggcggat gtgaggccgt aaatctcgct cctgaagcgc tcccacgtcg tcgtagtagt 7261 tcgcgaggtc agcgtcaccg gttgaaaaac ccttcggtga ctggcggaac agacggacaa 7321 gaggaatgcc aacagcaccc gcgatatcct ctttaaactc gctaagcagg tcagacagcc 7381 ctgcgaaaga ataggaatgt gtttcaaatt cgtcctccga atcaaacagg gacataccct 7441 cgttcgtctg gtactggcgg accatctcca tattcttgat aagcgcctca aacgctttac 7501 cgcctgtggc gataatttca cgcagctttt taatctttgc cgttcgcaga tgtgccttgt 7561 aggcaagctg ggcggcgccg acgctggtgc tatcgtagga agtcaggcga tcgaagatgc 7621 gctcgacaat ggacatcccc cattcgtttt cggtgatttt ctgctgatac ggcagtttca 7681 caccatccat gcggatcagg cggctgtggt gaacagtcca cgcaggcagc ccctgcgccg 7741 ttgtcacgat gtcatagaat tcaggcttgc cgaggttagg accaagtgcc ttaatgcgcc 7801 tggtgagctg tgggttaatc atccagcggt caagtacagc cagaccttta aagctgccct 7861 tgccaacctt atccagcacc agcggcgtca gcggtgcctg accttcaatc agaatcagtg 7921 ccaccgcccc gccatacagc cgggaccatt tcagcgtctc gttgatgcaa tcccaaagct 7981 gaagctcatc gaaccgtgat tccagaatgc cacgacgttt cgggtcaatc tcactggtga 8041 tccgcacgcc ctttttggtc atatcgtccg ctttcgaatc gactgcggcg ccaataatcc 8101 aggaggaacg ataagcccac tcgatgagca ggcggttgcg gctggtatag ttcgccctgt 8161 aggtcgatgc ggcatgctga ttaggctgct gcataccgac acgggcaaca aagttatcgt 8221 acgaatccgc cgtggcgact cgtcctgttt tcttcgccat ggtgactatt ctccggcttt 8281 tttggtactc gtggcggata ggataatttg ttaaaaaacg acccgattta acataatgac 8341 tgttacccgc accagccgga tccctcccat gatgaaatgt ccgccaaagg cttatttatc 8401 ggggttaagt ggctaaaagc gcgtgaataa aacatgcata aacagggtcg aaaaatgaat 8461 agcgtgaatt ttgcgtgaaa cggttatttc caggtattta gctgtttccc agcgcttccc 8521 agatatccat tgccgtatcg gttggagcaa acgccatgat gaacgcgtcg gccacgttcg 8581 gcgatggtac gtcacgcttg gcgaggtctt tcttgctttc caccatcacg cgaccgtttt 8641 tgtcaaaatc acggtgcggg gtggtaagtt ccagcttgag cttttccagc agcgggcagg 8701 atgagtcaat gctaatcagc tcatctaccg ggtactgctc gccgttcttt accgcgttga 8761 aggtgttacg gaagcgatcc gctaccagcc accaggcttg cgctttgagg ttggcgaaaa 8821 aatccttgtt cgggatccca ctatattcgt agtccggctc attcacacca gcgcctgcat 8881 tgaatcgctg ataattgatg cgggatgcat tcatgttttc gcgcttacga tcctcattaa 8941 tttctgagaa tttcgcgcca gcagatgccc caacgccgat tgagtcgtag acgatatcag 9001 catcgcgctc cagtgctgcc tgatacgtac gctggcagct cttcagcaat tcgtcttctt 9061 tcgccttcca ctcatccgcc caatacacga cggagccgtg acgatagacg ttagcgcact 9121 tatcggcgcc gctatcggcg acgtcgaagc caatacgctt acgcccgctt ggctcgaaat 9181 tcaggatttt gtgggcatca acagccgcct caatccatga cagcttgata atggccgcat 9241 catcatccga ctctggcacg ccttcgtaga cgtgcttaaa cccatccgga tcccggcgct 9301 tagcggcttc gataaccttc agcatcgtgt cggacaaaaa ggggttttca tcgtagttga 9361 ttttgcgtat cagcgtatct tctggcggat cgaccacaaa gttacgccaa acgaaatcag 9421 tcaccagtcc ggggttaaag ataaaccagc actctgagcc ctctttacgg atggtaggct 9481 ccagtatctt ccactggtac tccgtcagcg cgtgggcctc ttcaagccac agaacgctga 9541 taccttccag agacttaatc tcttcaatgt tgcgccagag cccataaaac acgaattcag 9601 acccggtcac ccggttaatg attttgttgt tcagaatgcg gaaacgatgc cgcaggccaa 9661 agcggtcaat ctgaattttg agcagggtat acaccgactc ttcaattttg ttctggatct 9721 gacgcgcaca acaaaagcgc aggctgtatt tatttgacag gaatatggcg atgccagcag 9781 catcccatga ctttgacgat gaccggccac cataaagcac tttgttacgc gcctgcgtcg 9841 tccagaagct acgcaggacc ggattcagcg tcggtttgga tgtcagagta gaagtcattg 9901 aggtcacgct ctccgttgcc atcatcaata ccagcatcac ggcgaagacg atcggcctcc 9961 agcgacacct tatcagtagc agccttgcga tagtctgtat cagcaaatat tttgcctacc 10021 gtcgcaagcg tgccgacgat ggactcaata cgaacggtat tgcgcatcat cgccttctcg 10081 gcggcgctga tattttccat cagcaccttt ctttcctggt ccccttcagc atcatccagc 10141 ttggtcaacc accggccaat attctctgcg gcgacaaggt tgttagcccg aaggcgaaat 10201 aattcgtctt cgagtgtcaa cgctttcgcg tcttcaatga cctcatcttt aagcagaaga 10261 cggcgggcat aaccaccgtg ttttaacgcc tgctggttgc cgggttgaaa tgggttagtc 10321 ggcggatcgg tacgcacccc gcgtatcggt ttcgtatctg gtggaggttc ggcttttggt 10381 tgcgtacggc cagagctggc aggcttttcg ctggtacgcg ccttactctt ttgcgtacca 10441 tttttgcgta cctgcgtact ggccttgcgt acccaatcaa actttttagc cctcttcctg 10501 atagcccctt cagtaacgcc gtatttatcg cctatatcac ggagactaag gactccggcc 10561 cggtatgccg attcgatggc ctcccagtcc ggtgttgcca taattttgtc ctcgccttga 10621 cattatcgag ccacctctgg aagtggctct gtaatgccca taaaaaaacc cgccgcagcg 10681 ggtttgggat aaagaatact ctctaaacca actcaccaat gaattttgca cttaccctaa 10741 gccgagcttg aggaattcct ttaacggccc ctgataaaag gtaacccccc tgcacttcta 10801 caatgctcat ttccatcgtg tagtcattta caccttgaat gacattcacc gcctgaggat 10861 tatgctgaga aacatgcaaa tctaatgtat cgccctgaat atggccttgg taagtgaacc 10921 cgaaatcacc accgttgatg gcattgtctt ttactactac agtgccttgt ccaacatcat 10981 ggttattgct gctgaaggtt acgaagtaaa taccgttttt catgtcacac cttatgttgt 11041 agccaatcgg caaaggcatt atagacacgc tacttacggg gagaaagatg gcattttaat 11101 aactgccgga tatgactaat ttttccctct aaatatttca gaccgacgta tgtcggcctt 11161 atcccggttg cactgcccca gcgctgatag cagactgacg tttaaatcaa ggctctggcc 11221 ccacgtcatc ttgtccggta tatcaggata aggcgtttca gctgtcaggc tggagggtag 11281 cggcactacc ggaacggtga cgtaaactgt ctttgtattg ctgcaaccgc ttaactgcgc 11341 cagcaggaat accagcggga gcgcaatcat cattcgcaac agccactttg atatccgccg 11401 cggctcccga tgcgtccagt gcgatctgct ctttggcatt tttgttggcc tccgcgatgg 11461 aattgaatat ggtcatggtg gtaagaacgt tggctgtgat ggcctgagtg ctgtttacct 11521 gctgctcggc gccatcggct cgggttttct gctcagcagc agcgttgtgg taatgcatta 11581 ccagccaccc aaggcaaacc atcaggcaga tcacaacagc gctgataatg gctgctaatc 11641 ggctcattca tctatccccc aacatgccag tgcgctttcc tgatcacgac gagagacctg 11701 gccgtaacaa ttgttcgaac gcacgcggca atcttttccg ccatcaaaaa tccaccggcg 11761 aatttcagcg caggcgcctt tccggtcacc ggcattcagc ttgcggtaga aggtggaagg 11821 aaagcattta ccgggcccga tgttataggg gcagaaactg gcaatcccga ccttttgagg 11881 gggtgtcaga ggaacacgca cattctgatc tacccatgcc agcgccttat tgcgctcgac 11941 ggcattaacc tgatcgcatt tggcctgggt taacttcatt ccctgggtta caggtcttcc 12001 atctacctgg gtaactccac gacatatcgt ccatatgccg gcgccatcgc ggtatgacgt 12061 gaggcttttg ccctctttct cattcaggaa ctggtccata agaacgggag ctgaagcgcc 12121 agcagcgata agcgccagca tggccgaact gagtttcgtt ttcaggttag ccatcgctat 12181 tcatcctgcg gtggcgggcc accatagcca cgatcgaggg attgctgata catcttcgtc 12241 cagcggcgct taaagtagag attggtcaga taagtcgcta caccgattat cacgccactg 12301 gccagggcaa taaaattcca gtcaaggcca tgaaaccagt cataggtcct tgccagcccg 12361 gtgcatatca ggccgcctga cgagcagtac gaggccgccg aaaagatttt gtcaggcatt 12421 ttcatagtct ccacctccga taatgttcgg ggtgctatct gtagtcagta aaaggttcag 12481 ggccgtcggg ctggatttaa caacgaagcg tgtcgatgat gattcccgtg agcctgaaat 12541 gaaaaaggcc acgcaaatgc gcagcctgta attgtcgcgg gtaaaattta attgtcgctc 12601 gttggacgct aacccgcttt tgacaacgcg cccatccaga gcgcggcctc aatggaggtc 12661 ttccagtcgg ccaacttttc agtcgccaga aacaaaaaaa cccgccgaag cgaggtttca 12721 tgttttaatt tcgtacgggc gttatatccc acgattgaaa gcatactaga cacttttatg 12781 caaagtcaat actatcatgc aaaaaatagc cgatatttgt tccgatcata ttaataactt 12841 gtcgctttct caaattctac tgcagcctga cgctccccct gacgcagcat gtccaccagc 12901 ccctcataga acggtttcca gttgcgtgac cacgaagact gatggagatc cgggagacgc 12961 ttcagaatgg cgcggtgaac cgtcgctgag ggtacaacag agaagccatt tccagagcag 13021 cgctcacatg ttttgaaaac cggtgcgcca agttctttgg tcgctttgcg atctaacacc 13081 tcccctttac caccacacct gcatcgcgca tggatcactt tctttcctcc acacactcca 13141 cagacccttt tcaccagttc atttctaatc tttggggcct tcacctcgac accgtctgca 13201 tcgaaaatac cagggtgctt aattacatct tcatggctgg aaataaagcc ggttccgctg 13261 cagctgtgac acgttgcgct ggtggccgcc gaacgtgagt actccgcaaa agcaaattgt 13321 gccagcgtca acatgcaggt gccgagcttg tcaccggcgg ctttgcggac atttttagga 13381 gcgtttttga tggcaaactg cgccagcgcc tgaattgcaa gctgttcatc cgttttgctg 13441 ataccagcct ttccgaagaa agcggccagg ccgaagcgtg ccctgctgct ggtcacaccg 13501 atcccggtca taatgtctgt gccattcagg cgattcgggg atgtgctttt cgcgtcgtcg 13561 gtgatatgca tgccctgagg gctaaagtgt ttgagggagg cttccagttt cattcttcgc 13621 actccccgac caggttcaaa ataatgcgat caaacagcga atcccgttcc tcaaaatagt 13681 cacatgccag taaccacttg cagactgtta atgcttcagc ccgggtaact ggtttcatgg 13741 cgcacaaaag gtcagtgagc cacccgcgcc gatcccagat aatctggacg tagccatcgc 13801 cattttgtgt tttatacctg tgacgaagta cggattccca gtaatcccat tcaatggtta 13861 catcgcttaa tgtccaggga gagaggagga tgtttttaaa acctttaatt tctcttacgc 13921 gaagttcttc cgcctcacga cttaagtttt tttcatcggc ccagtttgca taaatatgac 13981 tgaagcgctc cataacaagg cgctcagcat cagtaatttt ctcaggcgaa aagtcctgtt 14041 cgatggtgaa gaattggtta tgttgcagat tgttattgtt catcatgctg ccaccttttt 14101 atagaaaact tgttcacgaa cctgatcgcc gttcataagc atatcattga aatctccgtt 14161 atccggccag cgtatgctga ctttcaccag gtcgtttttc gccagcaggt ttgcgtgggc 14221 gcactcgaac gccgcggcat gtccagttgc agagtgcttg tccatgtcgg caaaaataat 14281 cagatgcttc acacctgccg ggacccggaa tttcttcata aacccgctgt tgattaccgc 14341 ccaggtgttg acgccataaa cctgataaca ggagagtgct gtttcgatac cttcggcaat 14401 gccgatcgtc gttgataccg gaaacatgcg aatggccaca gagcgggcgt gatccagata 14461 gctgtcctct tgaagcgact taagacgttt ggcgctatca atatctgcct tcctgtcgcc 14521 gtccagcagc gtctggtgca ggtaacaaag ctcagctttg tcatcggtag ccagggcata 14581 cagagcttga taaacgcgcc ccgcatggcg ttggcggtca caaaaacgga tgccttctgc 14641 cggcaggcga cttatcccac gttgaagaag gtaaccagcc gcgctagttc cccgtaaatc 14701 gagcaacttg gaaaacttac tgatgactcg ctggcgctgc cgcgccgccg aactgttaga 14761 aggcacgttg atgcgctgat agttattccc gatgagctgg tccacttctg cgcagatggc 14821 ggaaaagctt tttgactggg tcagggtcag cagcttcatc ccgtcaccgc taccgcatac 14881 acagatccat gtaccctgac cgtcacggtc atcaacgcga tacttccccc gcgccttaca 14941 gaccggacat tctcccttgt aatggttttt cccggtgata ggcggcagcc cgtaatattc 15001 aaaaatttct gaccaccggc cttttgctgc ttctgctgtt ttcatatcac tgactcgcac 15061 tatttacgtt tttctggagt tttcgttttg cttcgataat taattgcccg tcgctgccct 15121 caggaggctc atagttgata ctggcgctcg gaggtggaaa tagatcctgg tcaggtttct 15181 tccccatctg ctgcaggcgt tcgcggcgtt tagcaaattt gataagtttg tgtttgatgt 15241 gattgctgac ctccggtgtg atctccattg gaaagtcgct taagccgttg ggccattcgc 15301 cgaatttctc ctgaaaggta tgagcacacc agccatcgct gacaggtttc ccctgcgccg 15361 cacgatgacg ctggtaaaac ttgatctgac tccaccagga ctgcttgtcg cttttggtat 15421 aaaccgtttc gtgcttgctc atttttttga tgttgcgggt gccgtcagtc tcgacgtcct 15481 gaccaacgag cggtttaaat ccgcactttg ggcagacgta aacgccggat ggcttcatga 15541 aatgacattc ggggcattct ttcggaagtt tttcttcgcg ctccttagtt gcgccggcag 15601 cggccgcttt catgccgtcg tttgtggatg gcagatcgtc gtattcgatg gagtcaggga 15661 agccgaggcg atgcacagtg ccactgtgat caaaaatcag gcaggcatct ttcccgggtg 15721 cagttcgcag tccgcggccc agcgcctgca gccagcgaat ttcacttttt gtcggacggg 15781 cgtagataat gcagcgaaca tcactatcaa aaccggccac cagcacaccc acactgacga 15841 ttatttttgt ggcgccagtc tcgaagcggt ggatcatcgc ctgccgttct tcgtggggtg 15901 tttctgcgac catcacctca gcgttaatgc ccgccttgtt aaactgcatg gttacaaagt 15961 ttgcgtgggc cttgttaacg cagaacgcca ccgtaggaag gtcacgacca tgacgaagcc 16021 agttatcgac gatatcgccc accaggtcag aaccgcacat gatttccgcc agctgggact 16081 cgtcgtaatc agtaccgaac tctatagatg gcttcgtttc taccccgcta agatccggtt 16141 ttgttggggc gaaaaattcg tacttactga ggtcaccacg ctggatcaat tcgccaatcg 16201 tcgttggctt aatcaggtgt tgatagtaat ggcccaggaa cggcgcaaaa ggggtaccag 16261 ataaaccgat aaccttcgct tttttctccg ctgtgatccg ttcgatttct ttcaggatac 16321 ggcgtttacg caggtgcgcc tcatcgacaa taagcagatc gatgtttttg ggaaattcac 16381 gcctaatgag cgtgtcagcg ctcgcaatct ggatcagcag atttgggtcg tagttcgggt 16441 gatcacgcca gataaaacta atctggtctt ccggcaaccc gtattctgta aagcgctggg 16501 cggtctggtt aatcaggatc gtatacgggg cgacaaacag aacacgcata ccacgactaa 16561 ccaggccggc ggcgataaac gcagccaggc ctgttttgcc gcttccggtc ggtgcgtaga 16621 ccatgaagga atcgtgcgcc ttccaggtgc gccgcagcat gttaagccca cgttcctgtg 16681 caaagttcgg tgtgatgtta agcattgtca gccctttttg agttctactc ttccaggaag 16741 aaacattcct gacctcttgc cgggataccg tgtaccagtt tgctagtgcg ccgctctttt 16801 atggttctgc cttcaagatc ggtacctacc taacccatgt acctgtctgt tggaaaagga 16861 cgctattcct gccctaactc ccaactcccc ccaacccccc tcttccctct tccccatccc 16921 atgtactcgc aagctggtac aaagaacaaa aaacagtcaa ggattgttcc ctgctatcac 16981 ccggcacctt taagcccggt gaccaacgga tcgttactga gatccggcca ggggtggctg 17041 ggtcgtatac ccctgcagtg cgcgtccgtg tgcatccacg aatctgcgaa gcctcacatt 17101 ggcttcatgc cttgcccggt tctccttgcg gtatggaacg ggctcggctt cgaacgattc 17161 ctgatacaca gctgcataac gctgaatggc tttttgtcgt gctgctggcg tcaggctcag 17221 taactgctgc ttgatccatt cttcatctgc agatgcgtac acagatggga gcaaaccgtg 17281 gtcaggcctc atcccgtgca acatcatctg aaaatacctc gtccaaactt gtattcaggc 17341 caagctgttt aaacgcgctg acgatccgct ttccgactgc aacatcagga atccttcttc 17401 ctgtttcgta gtggctaacg gccccctggg agctatcaat cagcgcggcc agctctccct 17461 gagttacctt tgctttgcgt ctaaggctct tgattccact cattcgatta gtctcgcata 17521 aataatacat aacgtactat acacggtcac aagaataata caaaatggaa gttgctcagt 17581 aaatacggaa tgtaataatc atggctatga aacagagatg gcaggacctg gccaaaacca 17641 ggatgaaaga agtcggcatg actcaagaac agctggcaga ggcgctcggc ataacgcagg 17701 gcgggctggg ccattggtta aacgccagac gtgaaccgaa cttagaggtt atagctaaga 17761 tttttaacat attgaaaatg cccggcttcg tagtaaatgc tgacggcact atcagcgact 17821 caagagccga tcacaatgta agttttaata gcattaacga atccaaggga agctaccctg 17881 ttataagctg ggttagcgct ggagattgga tggaagctgt agaaccgtac caccgtagag 17941 cgatagatcg atggtatgac accaccgttg aatgctctga ggattcgttc tggttagacg 18001 tcagaggcga ttccatgaca tcaccagcag ggctgagcat accggaaggg atggcgatac 18061 ttgtcgatcc ccaagtggaa gcaatcaacg gaaaattggt tgtagcgaaa cttgacggtg 18121 acaatgaagc cactttcaaa aagcttgtta tcgatgccgg tcaaagattt ctcaaacccc 18181 tcaaccccca atacccaata atccctatca atggcaattg ccgtattatc ggggttgtag 18241 tcgacgcaaa aatcaccaac ctcccataaa ttggccgcga aagcggcttt ttttttgcct 18301 ccaacacccc accagaaact aaaaaacctt gaaaaacaaa atgatgtgaa ataacacacc 18361 aaaatactcc attttgtatt gatcttattt aatacgttat gtattgttta tgcattagcg 18421 gattaatgga gtgcaaaaga tgagtacaga gaaatttttt caactggtaa ctatacctga 18481 ttaccgtttc tcttccgata aagagcaatg tcaaaacatt gatttcgaca aaattgctac 18541 tgattgcgat acaaaaacaa tatctatttt gcaagccatc aatcatatag gggttagcat 18601 aatgagtgag gcagaagaaa agagattaaa taaagataaa ataatgatgc tttctagtgt 18661 ggttgcagac ctcgctgaat tagcaatagc aacaaataaa atagctaact cagcaacata 18721 ttcttccggt tataaggatg ctaaaaatgt ctgatatcac tttgcaaaaa gcagcatcaa 18781 aggcttacca ggctgagatt gtggcgagga tgcttgagaa ctaccctcat aaactgaccg 18841 actcagacgt ggaatctgtc gcctcacttt tggctgatct gattgggcca gttgcagcgt 18901 accttattga ggaagagtct aaaaacccgg cttaaaaatt taattagtaa ttttaattac 18961 aggagtaatc ccggggattt ctgcaatcaa attaagggta accatgatta ataaacaagc 19021 atttaaaaca gctcagttat ttgtctctct tggttattgg tctatagcca tgctttattt 19081 aaaaaaggct tacggtaaat aaaagtgaat aatttaatta gcacttatag acgcagaatt 19141 ttaaaagcgg ccttgttacg ccaccagcga aagactggga gtagcttact tgtcattaag 19201 ctcaacaagg gtgggattag tactatcgaa ttaactgaga ttcttcttga tggattgttg 19261 cggaaattcg agcgactggc gctcggtgaa tacggaaatg tggaaggtgt gaaagctctt 19321 aagggaattt acagcaactc tgttgatgtt aatggcagcg gcgaattcct cacagaaagc 19381 gggaaagagt taatcgacga gcttatttct gaactggttg agttcgtcaa aaagcagaaa 19441 ccagttactg cggagtccgg caatgaataa ccagcaaaca atgctctatc agggtgtgct 19501 gatcccccgc cccgtgttga acgtggatct gcatgtcctc cctgatttta ccgggcgggt 19561 agtcttgcac atcgagaacg ggagggtgat atgcgaccgc cagctgttcg acgacgagca 19621 catttgcaca ctggccacgt ttatcgaaat ggcccgcgac gcggggttga ggatcgagga 19681 ggaagctggt ggcactgaca gcgatacgaa ttcctgagag ggttcacctg caggcgctgc 19741 aggtcctgct gcggtatcgg cgccggcgga tattcccgcg gcgaatgcgc cgcaccggct 19801 acctcagcct gaaggttaac ccacgctggc gcctgttatc gaaagacgat ggccggaact 19861 gggaagttat gagtcatgaa acctataacc gggagaaaga caaatgattg acaacagaac 19921 tgtcagcgcc attgacctgg cgttgcaaaa gcacccaacg ccagttggtg atctgttcgc 19981 cgcgatccgc cacggacgca tgaagcggtg cttcagccgg gataccgcaa ttcgttacct 20041 ggcgttcttc atgacctccc gagcttttgg gcgttctggt ttcaagcagc gttatccgga 20101 cgtgcaggta attcatccac tgaatccaga actgagtagc tggcaacgtg gcgccgtgac 20161 cactgagtat tttaacgccc accagcgcac cgttcgccgg ctgcgtcgca tcctcgcccg 20221 caaaagagaa atgcaaaagt ggtgcaaaaa gtgggatgcc atgcacgacc gctacgtgaa 20281 agagcgcgaa gaactacagg cctgtaagcc tggagggctg agtcgatgat tgcttactta 20341 cgcattgttc tatcggtggt gattgtcgcc agcgtttatg ggctgttcgt tccgatcctc 20401 atttcgatga aggacacgac agcagttata tccggttttg ccctggcgat tctgaccccg 20461 ccgtgcatct acgccatttg taagggtctt gtgcttaccg taacgaagga aaagaaatga 20521 aaaaagcaat tatggcttca attatcgcac tctctgccat cggccttgtt ggttgcgatc 20581 gagttgagcc cggcaacgtg ggtatcaagg tgaataagtt gggcgacgat aaaggcgttg 20641 gtgaagtcgt cggcgtcggc cgctactgga ccggctggaa taccgaggtt tatatctttc 20701 cgaccttcaa gcagatgaaa acgtatgaag acgctttcaa cttccagatg agcgatggaa 20761 ccaccatcgg ctaccacatc ggggtcgcgt acaaggttga tccgaccaaa gttacaaccg 20821 ttttccagac ctaccgtaaa ggcgtggacg acatcaccga caccgacctg cggcagaaaa 20881 ttgctgacgc ccttaatcgt ctcgcaagtc ggatgagcac cgataaattc attgacggcg 20941 ggaaagctga gctgcttgaa aacgcactga aagagatcca gtccgatatg gggccggttg 21001 gtatccaggt gatcagcctt tcttacgttg gccgtccgga atacccgccg acagtgatcg 21061 aaagcatcaa cgccaaagtt acggccaacc agaagacgct gcagcgcgag caggaagtta 21121 aacaacgtga agctgaagcc aacatgttac gagccgaagc cgatggccag gcggatgcaa 21181 agctgaaatt ggctgaagca gaagcaaagt ctatccagat ccgtgggcag gccttgcgtg 21241 agaaccctga ggtactgcaa ctggaggcca tcaacaaatg gaatggcacc ctgccccagt 21301 acatgaccag cggaacaaac acccctttta tccaggttaa atgatccacc agcccggcga 21361 caagccgggc acatatgaga ggttcgcaat gcttcagaac atgcttaacc cggaaccaac 21421 ctcaacaggg atccggtctg gaaaccgggt gattggctac tccgctgcta ttcgcctgct 21481 ggataacggt cgctatgaca aacaccttgc cgatggaatg gaaattctgg cctgcatcat 21541 ggaagcggta gaaagcaact ggatcacgct caatatcgaa aaagagttga tcctctggcg 21601 ctggttactg gctgccgtgt tcatcactga ggagctggag aaaaacggaa ctgtcgacgt 21661 tccgaatgat actggcggtg ttgatactgc tgttatctat tccagcaagc atggcgccat 21721 tagcgtctat ccgggacctg aacgctttgc actcgccaac catattgagc tgggggcaat 21781 cgagaaatat gggccagagg ttggccagca gctggcgctg cggatgtatc aggacatggt 21841 tattgctgac gaagaatttg ggttcaggtt atcagcactt ggccgggagg ggcttaacct 21901 cctccatgac agctttatcg aacacatcca gatcgaaggt gtgcccgaag caccgattat 21961 gcattgaggg gaatgatgat gaataacttg atcactaaca aaccatccat gaccagcctt 22021 gagatcgccg agctggtaga aaaacgccac gacaacgtga aacgcacgat tgagaccctg 22081 attatgcgtg gcgttattac ttctcctcaa attgaggaaa agcctactgc cgggcgcccc 22141 acaacaattt acgtttttga aagtgaagaa gggaagcgtg acagcatcat tgtggtcgcg 22201 caactcagcc ccgagtttac cgccagactg gtagatcgct ggaaagagct ggaagaagaa 22261 cgctcccggc caaaatcgca ggcagagctg atcgctgaaa tggccctgct gaatgttgag 22321 caggaacgac gcctctacca ggttgaagaa caggtggaaa ccgtagtcga agctgtcgaa 22381 aacattaagc gtggaaatat gcgggccggg tatgtcggtt atcgccaggt ggtcgcaaaa 22441 agcggcatga ccgatgccaa gtgtcgaaac cttgttaacg cataccgtat cccaaccgat 22501 acacacgaat tcatgacgcc tgatggttta ctgtctcgcc gggcgatcgt ggagtttgaa 22561 ccttttatga aagcattccg ccaaatgatg gcagaagccg aaccacgtgg gacccgttgg 22621 tatcacccga aaatgggact ctttcaggct atcggatggg aggaaaaaca ttgtgaaaat 22681 tgagtttaat gatcaagggt cggtttcagt tatcacggtc accagcaccg tgtttgagtt 22741 ccgccggcac aaccgggcga ttgatgtcgc gttgttcctc acgcctgaaa ttaccagcca 22801 gagcagcggt tttttcatta tgaaaacgat cttaagcggg aagacacatc acgcgctgcg 22861 ggcctataaa catctgatcc gggaggctaa gcaatgagaa acggccagca ttatgcatac 22921 ccaaatccaa gcaacgcaac gcctggtggt atgacttatc gtcagtatct tatcgcaaaa 22981 attgcaccag ttatgatcac gaacttcttc agcaacgatg cttggacgga ttacgacgac 23041 ctcgccagaa ctctgatgat ggctgtggat gccatcatcg aagctgaaca ggagacagct 23101 gaatgacaat ctgcgaaaaa cggcttaaaa gaatcgccgg cggtgaacct ttcttcccgg 23161 gcgaggtggt tgcgatggct cttgagcttc tggcgaattc taaagaaaca ttgcggccgg 23221 aataccctga aacactcccc tgcccggtca ttcttgaacc cggcttccgg tttggcaaag 23281 gcgttggcac tcacctggtt ctgcgagcac ttaacaacag ggctaaacgt tacgctgaat 23341 tggatgccat gggtccagag gcccgcgcag agcatgatgc cgctatcgtt gaacttcggg 23401 aaaaactggg ttttggtacc caagcaaaaa cagctgtgca ggtgaagctt ccgggactgc 23461 cgcagctcgg atctaacgcc gaatggtatc agggatttgc tgctggtgca ggaagcatgc 23521 gcgaagcatg tgcggccgct ctgatttctg cgggtattga aattattggg gagacaatgt 23581 aatggactgg ccaacagcat tttgcatcgt cggttgtgcg tttgccatag cctggctgtt 23641 tcggagttag tgtcatgaat agagaatttg agatatggat cagactgcgc tacggcggcc 23701 gctatgacct aacgcgagac ggtcacggct actacagccg ggaagtagtt aagcggatgt 23761 atgaagtgtg gtgccactgc cgtggcctgg aagtggtgtg aggtgagtaa tatggtagac 23821 attgaaatga ttgacgagga agaggcgatg cggatgatcc gagtatcttc acgcgtgacc 23881 atccggaaat acaccgagcg ctataatttc cccaagccgg tccggaccta ccctaaacag 23941 tatctgcgct ctgctattgt ggagtggatc ttaaacgggg gagtcaacca gaaatcttcc 24001 tgatatgcca gaatatcttt tcagcataca gatcgtaggc gtctttctgt tcggcaatcc 24061 agtcatgctt gttatagaca gaaagcacgc caccaagctc atgccccagc attttttcga 24121 tgacgtgcgg ggcaaccccc tcttcggata gccgggttgc caaggtgcgc cggaaatcat 24181 gtgaagtaaa ctcaccaaac cccaacgagt ctttgattct tctcagaaat ttatttgcac 24241 cagaaatagt tatagggctt ttcaggtcct cgcccgggaa aagtatatcc ccatacgtca 24301 tttcagcttt tttcagcaaa tcatctgccg cggagaaaat tgggcgcctg ataattttgt 24361 tggttttgct tttctctgcc ggaacaaccc ataacccctc ctctcggtca aattcacccc 24421 ttatagccag ccgaagttcg ctattcctgg cgccgtacag cattagcaat tgatgaagca 24481 atcggttaga agttgaccct cgacttcttt ctatagccat ccaaattttg gcaagctggt 24541 tatagctgag tgtggtctct ccaatcacag gtttaacacc gatgtctttc ggctgcaaaa 24601 gcatgagctc ggttgtgcta acgaactgtc gccgcgtaca ccaaccaatg gcggacctga 24661 gctgtatcaa taaatgccgg gctcggcgag gattgatttt ctcctcttcg gtaaacctct 24721 caacccacaa gcggactggg atatcctcaa ccggaatacc gggaaaagcg tcacgcatgt 24781 gctttataac cgttgactta taaagcgcta tcgtcttagc ccttaacgtt acgtcaacgt 24841 aattttcctt ccagtaatcc aggcaatcct ttaccgttgg cttactcttg gatttgttgc 24901 caccagccag cgttcggggg tcaatgcctt tgtctgccga ctccctcagg tctgcaacga 24961 tattgcgggc atcgcgcagc gtcagcgctg ggtagcgtcc aagccccatt cggttctgct 25021 ttccttccca tcggaaccta aactgaaagc tgatcacgcc tttgggggtt atgcgaactc 25081 caagcccgtc agaatccgta atttcagcag gcccagaata tggtttacca tagatagagc 25141 gaagctttgt gtcactgatt gccatgttag ttttctgtac tcatcacttt ggtattttat 25201 gtacttattc tgtactcaat atcgcatgaa cgaacataaa caacaatatc aaatcatgta 25261 caaccatgcg caacaattgg cagcacaact aaaataataa taaaaaatca tatacataaa 25321 catctaaccg tattcattct tgtctgaaca atctcaacca tgtgcaaagc ccacaccttg 25381 ccgaagatta cgaaacgatg gttccttttc aggcactgca gatgattgga caccaggtcg 25441 atgccgtctg cccggataaa gccgctggcg actatgtcat gaccgcaatc catgactttg 25501 acggcgccca gacttatagc gaaaagccgg gccatcgctt cacgctgaac gctgacttcg 25561 ccgcagtaaa ggccgagaac tacgatgcgc tagtgatccc cggcggccgg gcgccggagt 25621 atct //