locus-tag	class	description
CSC00_0002	COG3316	Transposase and inactivated derivatives
CSC00_0003	COG3316	Transposase and inactivated derivatives
CSC00_0006	COG3316	Transposase and inactivated derivatives
CSC00_0016	COG3039	Transposase
CSC00_0017	COG1196	nuclear chromosome segregation
CSC00_0033	COG5484	DNA packaging
CSC00_0033	COG3728	DNA packaging
CSC00_0064	COG4171	peptide transport system, permease
CSC00_0067	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSC00_0070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CSC00_0072	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC00_0072	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC00_0075	COG1349	DNA-binding transcription factor activity
CSC00_0078	COG0023	Translation Initiation Factor
CSC00_0080	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CSC00_0081	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CSC00_0082	COG0671	phosphoesterase, PA-phosphatase related
CSC00_0084	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSC00_0089	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSC00_0093	COG0616	signal peptide processing
CSC00_0095	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0096	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CSC00_0097	COG1187	pseudouridine synthase activity
CSC00_0098	COG0583	DNA-binding transcription factor activity
CSC00_0100	COG0009	L-threonylcarbamoyladenylate synthase
CSC00_0102	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSC00_0103	COG0512	Glutamine amidotransferase of anthranilate synthase
CSC00_0103	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSC00_0104	COG0134	indole-3-glycerol-phosphate synthase activity
CSC00_0104	COG0135	phosphoribosylanthranilate isomerase activity
CSC00_0115	COG4774	siderophore transport
CSC00_0117	COG3047	cAMP biosynthetic process
CSC00_0122	COG1607	acyl-coa hydrolase
CSC00_0124	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC00_0125	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0126	COG1988	membrane-bound metal-dependent
CSC00_0129	COG0753	catalase activity
CSC00_0131	COG1486	melibiose metabolic process
CSC00_0132	COG2169	Transcriptional regulator
CSC00_0132	COG1917	Cupin 2, conserved barrel domain protein
CSC00_0133	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSC00_0134	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_0136	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_0137	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSC00_0139	COG0322	excinuclease ABC activity
CSC00_0140	COG3678	ATP-independent chaperone mediated protein folding
CSC00_0143	COG3724	N-succinylarginine dihydrolase activity
CSC00_0145	COG3138	arginine N-succinyltransferase
CSC00_0147	COG0708	Exodeoxyribonuclease III
CSC00_0148	COG0398	Pfam SNARE associated Golgi protein
CSC00_0149	COG0398	Pfam SNARE associated Golgi protein
CSC00_0150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC00_0151	COG4134	Bacterial extracellular solute-binding protein
CSC00_0152	COG4135	transport system, permease component
CSC00_0153	COG4136	ATPase activity
CSC00_0154	COG2897	thiosulfate sulfurtransferase activity
CSC00_0155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSC00_0156	COG0494	nUDIX hydrolase
CSC00_0157	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSC00_0159	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSC00_0160	COG0709	Synthesizes selenophosphate from selenide and ATP
CSC00_0162	COG2801	Transposase and inactivated derivatives
CSC00_0164	COG0778	Nitroreductase
CSC00_0165	COG0616	signal peptide processing
CSC00_0166	COG0252	asparaginase activity
CSC00_0167	COG1335	isochorismatase
CSC00_0168	COG2814	Major facilitator Superfamily
CSC00_0169	COG1349	DNA-binding transcription factor activity
CSC00_0170	COG0667	Aldo Keto reductase
CSC00_0171	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_0172	COG0191	fructose-bisphosphate aldolase activity
CSC00_0173	COG1063	alcohol dehydrogenase
CSC00_0174	COG2271	Major facilitator Superfamily
CSC00_0175	COG1063	alcohol dehydrogenase
CSC00_0177	COG1403	HNH endonuclease
CSC00_0178	COG3139	Protein of unknown function (DUF1315)
CSC00_0180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSC00_0182	COG0656	L-ascorbic acid biosynthetic process
CSC00_0183	COG3713	MltA-interacting MipA family protein
CSC00_0184	COG2766	serine protein kinase
CSC00_0187	COG0386	Belongs to the glutathione peroxidase family
CSC00_0192	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0193	COG0583	DNA-binding transcription factor activity
CSC00_0194	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSC00_0195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSC00_0196	COG3344	reverse transcriptase
CSC00_0198	COG0859	PFAM glycosyl transferase family 9
CSC00_0200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC00_0202	COG2207	Transcriptional regulator
CSC00_0203	COG2807	transmembrane transport
CSC00_0204	COG0504	CTP synthase activity
CSC00_0205	COG1683	Conserved Protein
CSC00_0206	COG3189	MarR family transcriptional regulator
CSC00_0207	COG3042	response to heat
CSC00_0208	COG2203	Gaf domain
CSC00_0208	COG2199	diguanylate cyclase activity
CSC00_0211	COG3182	Iron-regulated membrane protein
CSC00_0213	COG1560	Kdo2-lipid A biosynthetic process
CSC00_0216	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CSC00_0217	COG3706	GGDEF domain
CSC00_0218	COG0583	DNA-binding transcription factor activity
CSC00_0219	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSC00_0225	COG1294	oxidase, subunit
CSC00_0226	COG1271	oxidase subunit
CSC00_0227	COG3546	catalase activity
CSC00_0228	COG3685	Protein conserved in bacteria
CSC00_0229	COG3685	Protein conserved in bacteria
CSC00_0230	COG3729	General stress protein
CSC00_0232	COG1063	alcohol dehydrogenase
CSC00_0233	COG3813	Protein conserved in bacteria
CSC00_0236	COG0640	Transcriptional regulator
CSC00_0237	COG0538	isocitrate dehydrogenase activity
CSC00_0238	COG1187	pseudouridine synthase activity
CSC00_0242	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSC00_0246	COG2205	protein histidine kinase activity
CSC00_0247	COG2850	peptidyl-arginine hydroxylation
CSC00_0250	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC00_0251	COG1177	transmembrane transport
CSC00_0252	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC00_0254	COG0318	PFAM AMP-dependent synthetase and ligase
CSC00_0256	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CSC00_0258	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSC00_0260	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSC00_0262	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSC00_0263	COG1376	ErfK ybiS ycfS ynhG family protein
CSC00_0263	COG1388	LysM domain
CSC00_0266	COG1309	transcriptional regulator
CSC00_0269	COG3134	Outer membrane lipoprotein
CSC00_0270	COG1252	NADH dehydrogenase
CSC00_0275	COG5633	Lipoprotein
CSC00_0276	COG0537	adenosine 5'-monophosphoramidase activity
CSC00_0278	COG0084	hydrolase, TatD family'
CSC00_0279	COG0470	DNA polymerase III
CSC00_0281	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSC00_0282	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC00_0283	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC00_0285	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0286	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSC00_0290	COG1399	metal-binding, possibly nucleic acid-binding protein
CSC00_0293	COG1530	ribonuclease E activity
CSC00_0294	COG0583	DNA-binding transcription factor activity
CSC00_0295	COG2814	Major facilitator Superfamily
CSC00_0299	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC00_0310	COG1560	Kdo2-lipid A biosynthetic process
CSC00_0313	COG5645	(Lipo)protein
CSC00_0320	COG3381	protein complex oligomerization
CSC00_0324	COG0583	DNA-binding transcription factor activity
CSC00_0326	COG1335	isochorismatase
CSC00_0329	COG1702	phosphate starvation-inducible protein PhoH
CSC00_0332	COG0672	)-iron permease
CSC00_0333	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC00_0335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSC00_0338	COG1309	transcriptional regulator
CSC00_0345	COG2233	PERMEase
CSC00_0351	COG1733	regulation of RNA biosynthetic process
CSC00_0352	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0355	COG0531	amino acid
CSC00_0356	COG0174	glutamine synthetase
CSC00_0357	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CSC00_0358	COG1917	Cupin 2, conserved barrel domain protein
CSC00_0358	COG1396	sequence-specific DNA binding
CSC00_0359	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_0360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC00_0361	COG0583	DNA-binding transcription factor activity
CSC00_0362	COG0473	3-isopropylmalate dehydrogenase activity
CSC00_0363	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC00_0364	COG4638	Rieske (2fe-2S)
CSC00_0365	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_0366	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC00_0368	COG2200	EAL domain
CSC00_0369	COG2200	EAL domain
CSC00_0373	COG0670	Belongs to the BI1 family
CSC00_0376	COG2207	Transcriptional regulator
CSC00_0377	COG1881	PFAM PEBP family protein
CSC00_0380	COG1832	CoA-binding protein
CSC00_0382	COG0210	DNA helicase
CSC00_0383	COG3304	Inner membrane component domain
CSC00_0384	COG1289	transmembrane transporter activity
CSC00_0385	COG3070	regulator of competence-specific genes
CSC00_0390	COG1067	ATP-dependent peptidase activity
CSC00_0393	COG3009	Protein conserved in bacteria
CSC00_0394	COG3008	intermembrane lipid transfer
CSC00_0394	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSC00_0395	COG2995	paraquat-inducible protein a
CSC00_0396	COG0488	(ABC) transporter
CSC00_0398	COG0633	Ferredoxin
CSC00_0398	COG3217	Mosc domain protein beta barrel domain protein
CSC00_0401	COG0431	NADPH-dependent FMN reductase
CSC00_0402	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC00_0403	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_0404	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC00_0406	COG0308	aminopeptidase N
CSC00_0408	COG1473	amidohydrolase
CSC00_0410	COG0814	amino acid
CSC00_0412	COG1522	sequence-specific DNA binding
CSC00_0414	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSC00_0415	COG1448	Aminotransferase
CSC00_0416	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC00_0417	COG3108	Peptidase M15
CSC00_0418	COG2989	Protein conserved in bacteria
CSC00_0421	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CSC00_0423	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSC00_0424	COG3173	Aminoglycoside phosphotransferase
CSC00_0427	COG3214	Protein conserved in bacteria
CSC00_0430	COG0658	competence protein
CSC00_0430	COG2333	competence protein COMEC
CSC00_0432	COG0539	negative regulation of cytoplasmic translation
CSC00_0436	COG2323	membrane
CSC00_0437	COG1944	ATP diphosphatase activity
CSC00_0438	COG2116	formate transmembrane transporter activity
CSC00_0439	COG1882	Formate acetyltransferase
CSC00_0440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CSC00_0441	COG0477	Major facilitator Superfamily
CSC00_0443	COG3302	dmso reductase anchor subunit
CSC00_0444	COG0437	4 iron, 4 sulfur cluster binding
CSC00_0445	COG0243	molybdopterin cofactor binding
CSC00_0447	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSC00_0449	COG1178	ABC-type Fe3 transport system permease component
CSC00_0449	COG1674	ftsk spoiiie
CSC00_0452	COG0492	ferredoxin-NADP+ reductase activity
CSC00_0453	COG4988	ABC transporter
CSC00_0454	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSC00_0457	COG0542	response to heat
CSC00_0459	COG1278	Cold shock
CSC00_0461	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_0462	COG3593	DNA synthesis involved in DNA repair
CSC00_0464	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSC00_0466	COG2431	L-lysine efflux transmembrane transporter activity
CSC00_0468	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC00_0470	COG0028	Belongs to the TPP enzyme family
CSC00_0471	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CSC00_0472	COG0702	epimerase
CSC00_0473	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC00_0474	COG3023	N-Acetylmuramoyl-L-alanine amidase
CSC00_0475	COG3706	GGDEF domain
CSC00_0475	COG4251	negative regulation of phosphorylation
CSC00_0475	COG5001	Diguanylate cyclase
CSC00_0475	COG2203	Gaf domain
CSC00_0477	COG1126	abc transporter atp-binding protein
CSC00_0478	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_0479	COG4215	(ABC) transporter
CSC00_0480	COG4160	amino acid transport
CSC00_0481	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_0482	COG5002	protein histidine kinase activity
CSC00_0483	COG0745	RESPONSE REGULATOR receiver
CSC00_0486	COG1177	transmembrane transport
CSC00_0487	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC00_0488	COG3842	ATPase activity
CSC00_0489	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC00_0492	COG0778	Nitroreductase
CSC00_0493	COG0778	Nitroreductase
CSC00_0495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSC00_0499	COG3226	Transcriptional regulator
CSC00_0500	COG0738	Major facilitator superfamily
CSC00_0501	COG0561	phosphatase activity
CSC00_0502	COG2814	Major facilitator Superfamily
CSC00_0503	COG0671	phosphoesterase, PA-phosphatase related
CSC00_0504	COG1349	DNA-binding transcription factor activity
CSC00_0505	COG1686	Belongs to the peptidase S11 family
CSC00_0507	COG0625	glutathione transferase activity
CSC00_0508	COG2133	pyrroloquinoline quinone binding
CSC00_0511	COG2223	nitrite transmembrane transporter activity
CSC00_0515	COG0747	negative chemotaxis
CSC00_0518	COG0303	'Molybdopterin
CSC00_0519	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSC00_0520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CSC00_0522	COG0561	phosphatase activity
CSC00_0524	COG1609	Transcriptional regulator
CSC00_0525	COG2271	Major facilitator Superfamily
CSC00_0527	COG0488	(ABC) transporter
CSC00_0528	COG2365	Tyrosine phosphatase family
CSC00_0529	COG1376	ErfK ybiS ycfS ynhG family protein
CSC00_0530	COG2188	Transcriptional regulator
CSC00_0531	COG2723	6-phospho-beta-galactosidase activity
CSC00_0532	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSC00_0533	COG1321	iron dependent repressor
CSC00_0535	COG2194	sulfuric ester hydrolase activity
CSC00_0536	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSC00_0540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_0541	COG0765	amino acid transport
CSC00_0542	COG1126	abc transporter atp-binding protein
CSC00_0543	COG0668	transmembrane transport
CSC00_0545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC00_0547	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSC00_0549	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSC00_0550	COG1199	ATP-dependent helicase activity
CSC00_0551	COG0513	Belongs to the DEAD box helicase family
CSC00_0552	COG3958	Transketolase
CSC00_0553	COG3959	Transketolase, thiamine diphosphate binding domain
CSC00_0554	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0555	COG2271	Major facilitator Superfamily
CSC00_0557	COG0583	DNA-binding transcription factor activity
CSC00_0558	COG1309	transcriptional regulator
CSC00_0559	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_0560	COG1131	(ABC) transporter
CSC00_0561	COG0842	Transport permease protein
CSC00_0562	COG0842	Transport permease protein
CSC00_0564	COG3568	Endonuclease Exonuclease Phosphatase
CSC00_0565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSC00_0566	COG0392	lysyltransferase activity
CSC00_0567	COG0670	Belongs to the BI1 family
CSC00_0568	COG0314	molybdopterin synthase activity
CSC00_0569	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CSC00_0571	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSC00_0575	COG0745	RESPONSE REGULATOR receiver
CSC00_0576	COG0642	Histidine kinase
CSC00_0580	COG2226	methyltransferase
CSC00_0583	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSC00_0584	COG1881	PFAM PEBP family protein
CSC00_0592	COG4677	pectinesterase activity
CSC00_0598	COG0789	Transcriptional regulator
CSC00_0599	COG2200	EAL domain
CSC00_0604	COG0561	phosphatase activity
CSC00_0605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSC00_0606	COG4149	molybdate abc transporter
CSC00_0607	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSC00_0609	COG3585	molybdate ion transport
CSC00_0609	COG2005	Transcriptional regulator
CSC00_0610	COG1119	ATPase activity
CSC00_0613	COG1085	galactose-1-phosphate uridylyltransferase
CSC00_0615	COG2017	converts alpha-aldose to the beta-anomer
CSC00_0617	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSC00_0620	COG3201	nicotinamide mononucleotide transporter
CSC00_0621	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSC00_0630	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CSC00_0631	COG2885	chlorophyll binding
CSC00_0633	COG3064	Membrane
CSC00_0634	COG0848	biopolymer transport protein
CSC00_0635	COG0811	peptide transport
CSC00_0636	COG0824	Thioesterase
CSC00_0637	COG3790	cyd operon protein YbgE
CSC00_0638	COG4890	Cyd operon protein YbgT
CSC00_0639	COG1294	oxidase, subunit
CSC00_0640	COG1271	oxidase subunit
CSC00_0643	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSC00_0645	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC00_0646	COG0567	Dehydrogenase, E1 component
CSC00_0647	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSC00_0648	COG1053	succinate dehydrogenase
CSC00_0650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSC00_0651	COG2009	succinate dehydrogenase
CSC00_0659	COG1984	allophanate hydrolase subunit 2
CSC00_0660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSC00_0661	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSC00_0663	COG0415	Belongs to the DNA photolyase family
CSC00_0668	COG2205	protein histidine kinase activity
CSC00_0669	COG0745	RESPONSE REGULATOR receiver
CSC00_0671	COG0033	Phosphoglucomutase
CSC00_0673	COG0596	Alpha beta hydrolase
CSC00_0676	COG0735	belongs to the Fur family
CSC00_0683	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSC00_0684	COG1940	carbohydrate kinase activity
CSC00_0684	COG1846	Transcriptional regulator
CSC00_0685	COG0647	UMP catabolic process
CSC00_0686	COG0367	asparagine synthase
CSC00_0694	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSC00_0696	COG1702	phosphate starvation-inducible protein PhoH
CSC00_0698	COG4535	Mg2 and Co2 transporter CorC
CSC00_0701	COG0765	amino acid transport
CSC00_0702	COG0765	amino acid transport
CSC00_0703	COG1126	abc transporter atp-binding protein
CSC00_0707	COG2888	peptidyl-tyrosine sulfation
CSC00_0710	COG1466	dna polymerase III delta subunit
CSC00_0713	COG0799	negative regulation of ribosome biogenesis
CSC00_0715	COG0768	penicillin binding
CSC00_0716	COG0772	Belongs to the SEDS family
CSC00_0717	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSC00_0718	COG1686	Belongs to the peptidase S11 family
CSC00_0721	COG0583	DNA-binding transcription factor activity
CSC00_0724	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSC00_0726	COG1278	Cold shock
CSC00_0729	COG3069	C4-dicarboxylate transmembrane transporter activity
CSC00_0730	COG3719	Belongs to the RNase T2 family
CSC00_0731	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSC00_0732	COG0589	response to stress
CSC00_0734	COG0450	alkyl hydroperoxide reductase
CSC00_0735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSC00_0736	COG0583	DNA-binding transcription factor activity
CSC00_0737	COG3969	phosphoadenosine phosphosulfate
CSC00_0738	COG1475	DNA binding
CSC00_0739	COG0436	Aminotransferase
CSC00_0744	COG1129	ABC transporter
CSC00_0745	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_0746	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_0748	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC00_0751	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSC00_0753	COG0402	S-adenosylhomocysteine deaminase activity
CSC00_0755	COG0483	inositol monophosphate 1-phosphatase activity
CSC00_0756	COG2271	Major facilitator Superfamily
CSC00_0762	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_0763	COG1129	ABC transporter
CSC00_0765	COG0371	Dehydrogenase
CSC00_0766	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0769	COG2879	small protein
CSC00_0770	COG1966	Carbon starvation protein
CSC00_0772	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0773	COG3433	isochorismatase activity
CSC00_0773	COG1535	isochorismatase
CSC00_0774	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSC00_0775	COG1169	isochorismate synthase
CSC00_0776	COG4592	Periplasmic binding protein
CSC00_0778	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_0779	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_0780	COG1120	ATPase activity
CSC00_0781	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CSC00_0781	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSC00_0782	COG3251	PFAM MbtH domain protein
CSC00_0783	COG2382	esterase
CSC00_0784	COG4771	TonB-dependent receptor
CSC00_0785	COG2977	Belongs to the P-Pant transferase superfamily
CSC00_0786	COG3958	Transketolase
CSC00_0787	COG3959	Transketolase, thiamine diphosphate binding domain
CSC00_0788	COG2390	Transcriptional regulator
CSC00_0789	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSC00_0790	COG1879	ABC-type sugar transport system periplasmic component
CSC00_0792	COG1129	ABC transporter
CSC00_0793	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_0795	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_0798	COG0583	DNA-binding transcription factor activity
CSC00_0799	COG0668	transmembrane transport
CSC00_0801	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC00_0806	COG0747	negative chemotaxis
CSC00_0807	COG0601	transmembrane transport
CSC00_0808	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC00_0809	COG0444	Belongs to the ABC transporter superfamily
CSC00_0810	COG4608	Belongs to the ABC transporter superfamily
CSC00_0813	COG4221	oxidoreductase activity
CSC00_0815	COG4215	(ABC) transporter
CSC00_0816	COG0765	amino acid transport
CSC00_0817	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CSC00_0820	COG0697	spore germination
CSC00_0822	COG3698	Phosphodiester glycosidase
CSC00_0823	COG2801	Transposase and inactivated derivatives
CSC00_0833	COG2315	Protein conserved in bacteria
CSC00_0834	COG0778	Nitroreductase
CSC00_0836	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_0838	COG3716	PTS system mannose fructose sorbose family IID component
CSC00_0839	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC00_0840	COG2222	sugar isomerase
CSC00_0841	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CSC00_0841	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSC00_0844	COG0477	Major facilitator Superfamily
CSC00_0845	COG0668	transmembrane transport
CSC00_0852	COG3188	usher protein
CSC00_0855	COG2771	luxR family
CSC00_0858	COG0673	inositol 2-dehydrogenase activity
CSC00_0860	COG2211	Major facilitator Superfamily
CSC00_0861	COG1113	amino acid transport
CSC00_0864	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_0865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSC00_0867	COG0531	amino acid
CSC00_0876	COG0667	Aldo Keto reductase
CSC00_0877	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_0878	COG1473	amidohydrolase
CSC00_0885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_0886	COG1120	ATPase activity
CSC00_0887	COG1566	PFAM secretion protein HlyD family protein
CSC00_0898	COG4211	Belongs to the binding-protein-dependent transport system permease family
CSC00_0899	COG1129	ABC transporter
CSC00_0902	COG0673	inositol 2-dehydrogenase activity
CSC00_0908	COG3104	oligopeptide transport
CSC00_0909	COG1982	Orn Lys Arg decarboxylase major
CSC00_0910	COG0531	amino acid
CSC00_0911	COG3710	Transcriptional regulator
CSC00_0913	COG1560	Kdo2-lipid A biosynthetic process
CSC00_0916	COG3188	usher protein
CSC00_0917	COG3121	Chaperone
CSC00_0918	COG3539	Fimbrial protein
CSC00_0927	COG2501	S4 domain
CSC00_0929	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSC00_0932	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSC00_0933	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSC00_0937	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSC00_0938	COG4181	ATPase activity
CSC00_0939	COG2755	lipolytic protein G-D-S-L family
CSC00_0940	COG0300	oxidoreductase activity
CSC00_0941	COG3118	belongs to the thioredoxin family
CSC00_0942	COG0390	transport system, permease component
CSC00_0943	COG4619	ABC transporter
CSC00_0944	COG0330	HflC and HflK could
CSC00_0945	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSC00_0948	COG3735	TraB family
CSC00_0949	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC00_0951	COG2223	nitrite transmembrane transporter activity
CSC00_0953	COG4651	solute:proton antiporter activity
CSC00_0953	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSC00_0954	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_0962	COG2832	Protein of unknown function (DUF454)
CSC00_0963	COG3923	Primosomal replication protein n
CSC00_0965	COG5464	transposase or invertase
CSC00_0966	COG1196	nuclear chromosome segregation
CSC00_0966	COG3264	Mechanosensitive ion channel
CSC00_0967	COG1309	transcriptional regulator
CSC00_0968	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_0969	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC00_0972	COG0110	maltose O-acetyltransferase activity
CSC00_0982	COG1874	Beta-galactosidase
CSC00_0983	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CSC00_0984	COG3833	ABC-type maltose transport systems, permease component
CSC00_0985	COG1175	transmembrane transport
CSC00_0986	COG2182	Extracellular solute-binding protein
CSC00_0989	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSC00_0992	COG2364	Membrane
CSC00_0997	COG3695	enzyme binding
CSC00_0998	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CSC00_0999	COG1946	Acyl-CoA thioesterase
CSC00_1000	COG0004	ammonium transporteR
CSC00_1001	COG0347	Belongs to the P(II) protein family
CSC00_1002	COG1132	(ABC) transporter
CSC00_1003	COG1132	(ABC) transporter
CSC00_1004	COG1522	sequence-specific DNA binding
CSC00_1007	COG4533	DNA binding
CSC00_1009	COG0824	Thioesterase
CSC00_1010	COG1555	photosystem II stabilization
CSC00_1011	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC00_1012	COG3316	Transposase and inactivated derivatives
CSC00_1017	COG0776	regulation of translation
CSC00_1018	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CSC00_1023	COG0271	Belongs to the BolA IbaG family
CSC00_1024	COG3056	Lipoprotein
CSC00_1025	COG2223	nitrite transmembrane transporter activity
CSC00_1026	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSC00_1027	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSC00_1028	COG1845	cytochrome c oxidase, subunit III
CSC00_1029	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CSC00_1032	COG1414	Transcriptional regulator
CSC00_1033	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSC00_1034	COG1053	succinate dehydrogenase
CSC00_1036	COG1053	succinate dehydrogenase
CSC00_1039	COG0673	inositol 2-dehydrogenase activity
CSC00_1040	COG2814	Major facilitator Superfamily
CSC00_1042	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSC00_1043	COG0693	protein deglycase activity
CSC00_1047	COG0142	geranyltranstransferase activity
CSC00_1049	COG0667	Aldo Keto reductase
CSC00_1050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSC00_1054	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC00_1054	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSC00_1056	COG4238	major outer membrane lipoprotein
CSC00_1061	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC00_1062	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSC00_1063	COG1862	Preprotein translocase
CSC00_1068	COG0450	alkyl hydroperoxide reductase
CSC00_1070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_1073	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_1075	COG1228	amidohydrolase
CSC00_1077	COG1335	isochorismatase
CSC00_1079	COG0583	DNA-binding transcription factor activity
CSC00_1080	COG0366	Alpha amylase catalytic
CSC00_1082	COG1114	Component of the transport system for branched-chain amino acids
CSC00_1085	COG0420	3'-5' exonuclease activity
CSC00_1086	COG0419	ATPase involved in DNA repair
CSC00_1087	COG1940	carbohydrate kinase activity
CSC00_1090	COG4126	flavin adenine dinucleotide binding
CSC00_1092	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSC00_1093	COG3416	Protein conserved in bacteria
CSC00_1095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSC00_1097	COG1785	Belongs to the alkaline phosphatase family
CSC00_1101	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSC00_1105	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSC00_1106	COG1335	isochorismatase
CSC00_1107	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSC00_1108	COG0113	porphobilinogen synthase activity
CSC00_1110	COG2175	clavaminate synthase activity
CSC00_1111	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC00_1112	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CSC00_1113	COG4521	taurine ABC transporter
CSC00_1114	COG2040	homocysteine
CSC00_1115	COG0833	amino acid
CSC00_1118	COG4303	Ethanolamine ammonia lyase large subunit
CSC00_1119	COG4302	ethanolamine ammonia-lyase activity
CSC00_1124	COG0411	ABC transporter
CSC00_1125	COG0410	ABC transporter
CSC00_1127	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_1128	COG1126	abc transporter atp-binding protein
CSC00_1129	COG0765	amino acid transport
CSC00_1130	COG0765	amino acid transport
CSC00_1131	COG3121	Chaperone
CSC00_1133	COG3188	usher protein
CSC00_1139	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CSC00_1141	COG3639	organic phosphonate transmembrane transporter activity
CSC00_1145	COG0791	NLP P60 protein
CSC00_1151	COG0582	viral genome integration into host DNA
CSC00_1152	COG1192	Involved in chromosome partitioning
CSC00_1167	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSC00_1168	COG0022	dehydrogenase e1 component
CSC00_1169	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC00_1170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC00_1172	COG1830	Aldolase
CSC00_1174	COG1070	Carbohydrate kinase
CSC00_1175	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_1176	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC00_1177	COG3775	system Galactitol-specific IIC component
CSC00_1178	COG0625	glutathione transferase activity
CSC00_1179	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CSC00_1182	COG0579	oxidoreductase
CSC00_1183	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_1184	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC00_1185	COG1113	amino acid transport
CSC00_1186	COG1802	Transcriptional regulator
CSC00_1190	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSC00_1191	COG0454	-acetyltransferase
CSC00_1194	COG2991	Protein conserved in bacteria
CSC00_1197	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSC00_1198	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSC00_1202	COG3034	peptidoglycan biosynthetic process
CSC00_1203	COG0121	glutamine amidotransferase
CSC00_1205	COG1960	acyl-CoA dehydrogenase activity
CSC00_1206	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSC00_1208	COG0583	DNA-binding transcription factor activity
CSC00_1210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSC00_1212	COG2226	methyltransferase
CSC00_1214	COG0741	lytic transglycosylase activity
CSC00_1214	COG1388	LysM domain
CSC00_1215	COG2226	methyltransferase
CSC00_1217	COG2814	Major facilitator Superfamily
CSC00_1218	COG0583	DNA-binding transcription factor activity
CSC00_1219	COG0656	L-ascorbic acid biosynthetic process
CSC00_1226	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSC00_1228	COG2011	ABC-type metal ion transport system permease component
CSC00_1229	COG1464	Belongs to the NlpA lipoprotein family
CSC00_1231	COG1720	tRNA m6t6A37 methyltransferase activity
CSC00_1233	COG0791	NLP P60 protein
CSC00_1234	COG3015	lipoprotein NlpE involved in copper resistance
CSC00_1235	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CSC00_1236	COG4681	YaeQ
CSC00_1237	COG4568	rho-dependent transcription termination
CSC00_1239	COG0346	lactoylglutathione lyase activity
CSC00_1248	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CSC00_1250	COG0750	zinc metalloprotease
CSC00_1251	COG0575	Belongs to the CDS family
CSC00_1253	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSC00_1258	COG0024	Methionine aminopeptidase
CSC00_1259	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CSC00_1262	COG3835	regulator
CSC00_1263	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC00_1267	COG2860	membrane
CSC00_1271	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_1272	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSC00_1273	COG1120	ATPase activity
CSC00_1274	COG4774	siderophore transport
CSC00_1276	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSC00_1296	COG1643	Atp-dependent helicase
CSC00_1297	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CSC00_1299	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSC00_1301	COG0617	tRNA 3'-terminal CCA addition
CSC00_1302	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSC00_1306	COG0726	polysaccharide deacetylase
CSC00_1307	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_1308	COG0842	Transport permease protein
CSC00_1309	COG1131	(ABC) transporter
CSC00_1310	COG0288	reversible hydration of carbon dioxide
CSC00_1313	COG4993	Dehydrogenase
CSC00_1314	COG2132	Multicopper oxidase
CSC00_1327	COG3064	Membrane
CSC00_1330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC00_1331	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSC00_1332	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CSC00_1333	COG2186	Transcriptional regulator
CSC00_1335	COG1113	amino acid transport
CSC00_1336	COG2211	Major facilitator Superfamily
CSC00_1337	COG3940	Belongs to the glycosyl hydrolase 43 family
CSC00_1338	COG3725	Membrane protein required for beta-lactamase induction
CSC00_1341	COG4969	Belongs to the N-Me-Phe pilin family
CSC00_1342	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSC00_1343	COG1459	type II secretion system
CSC00_1346	COG0237	dephospho-CoA kinase activity
CSC00_1349	COG0494	nUDIX hydrolase
CSC00_1353	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSC00_1354	COG0849	cell division
CSC00_1356	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSC00_1359	COG0772	Belongs to the SEDS family
CSC00_1362	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSC00_1363	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSC00_1364	COG0768	penicillin binding
CSC00_1368	COG1609	Transcriptional regulator
CSC00_1370	COG0028	Belongs to the TPP enzyme family
CSC00_1380	COG0738	Major facilitator superfamily
CSC00_1382	COG0583	DNA-binding transcription factor activity
CSC00_1383	COG2271	Major facilitator Superfamily
CSC00_1384	COG2814	Major facilitator Superfamily
CSC00_1387	COG4143	(ABC) transporter
CSC00_1388	COG1178	ABC-type Fe3 transport system permease component
CSC00_1390	COG0586	Pfam SNARE associated Golgi protein
CSC00_1395	COG0235	Class ii aldolase
CSC00_1396	COG0417	DNA replication proofreading
CSC00_1398	COG0564	pseudouridine synthase activity
CSC00_1400	COG3493	citrate carrier protein
CSC00_1403	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CSC00_1404	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CSC00_1406	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSC00_1415	COG0505	Belongs to the CarA family
CSC00_1430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSC00_1434	COG1047	Peptidyl-prolyl cis-trans
CSC00_1437	COG0196	riboflavin kinase activity
CSC00_1440	COG0583	DNA-binding transcription factor activity
CSC00_1445	COG4735	regulation of single-species biofilm formation
CSC00_1446	COG1584	GPR1 FUN34 yaaH family protein
CSC00_1447	COG0477	Major facilitator Superfamily
CSC00_1448	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSC00_1450	COG1115	amino acid carrier protein
CSC00_1453	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSC00_1455	COG0460	homoserine dehydrogenase
CSC00_1455	COG0527	aspartate kinase activity
CSC00_1457	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CSC00_1458	COG0745	RESPONSE REGULATOR receiver
CSC00_1459	COG4452	Inner membrane protein CreD
CSC00_1460	COG2205	protein histidine kinase activity
CSC00_1461	COG0745	RESPONSE REGULATOR receiver
CSC00_1462	COG3045	CreA protein
CSC00_1463	COG3708	Transcriptional regulator
CSC00_1463	COG2207	Transcriptional regulator
CSC00_1467	COG0741	lytic transglycosylase activity
CSC00_1469	COG0488	(ABC) transporter
CSC00_1471	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSC00_1472	COG0560	Phosphoserine phosphatase
CSC00_1479	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC00_1480	COG0084	hydrolase, TatD family'
CSC00_1481	COG4667	esterase of the alpha-beta hydrolase superfamily
CSC00_1483	COG2823	Periplasmic or secreted lipoprotein
CSC00_1485	COG1011	Hydrolase
CSC00_1486	COG0456	acetyltransferase
CSC00_1487	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CSC00_1494	COG3706	GGDEF domain
CSC00_1495	COG4114	ferric iron reductase
CSC00_1496	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_1496	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_1497	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSC00_1498	COG2197	response regulator
CSC00_1499	COG2197	response regulator
CSC00_1503	COG2966	Psort location CytoplasmicMembrane, score
CSC00_1506	COG1484	DNA-dependent DNA replication
CSC00_1509	COG5464	transposase or invertase
CSC00_1511	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC00_1512	COG3716	PTS system mannose fructose sorbose family IID component
CSC00_1513	COG3715	PTS system
CSC00_1516	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSC00_1516	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CSC00_1518	COG1063	alcohol dehydrogenase
CSC00_1519	COG1802	Transcriptional regulator
CSC00_1520	COG2271	Major facilitator Superfamily
CSC00_1521	COG0456	acetyltransferase
CSC00_1521	COG1214	PFAM Peptidase M22, glycoprotease
CSC00_1523	COG1737	Transcriptional regulator
CSC00_1524	COG0800	Aldolase
CSC00_1525	COG3734	2-keto-3-deoxy-galactonokinase
CSC00_1528	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CSC00_1534	COG1846	Transcriptional regulator
CSC00_1536	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSC00_1538	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_1539	COG3384	dioxygenase
CSC00_1541	COG3971	2-oxopent-4-enoate hydratase activity
CSC00_1545	COG2368	4-hydroxyphenylacetate
CSC00_1546	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC00_1549	COG1966	Carbon starvation protein
CSC00_1550	COG2879	small protein
CSC00_1551	COG0523	cobalamin synthesis protein
CSC00_1553	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_1554	COG5464	transposase or invertase
CSC00_1555	COG2207	Transcriptional regulator
CSC00_1555	COG1917	Cupin 2, conserved barrel domain protein
CSC00_1557	COG2733	membrane
CSC00_1558	COG2814	Major facilitator Superfamily
CSC00_1560	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CSC00_1561	COG1924	4 iron, 4 sulfur cluster binding
CSC00_1564	COG1566	PFAM secretion protein HlyD family protein
CSC00_1566	COG5457	Domain of unknown function (DUF1127)
CSC00_1567	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC00_1569	COG0583	DNA-binding transcription factor activity
CSC00_1570	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSC00_1572	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_1573	COG1129	ABC transporter
CSC00_1574	COG1879	ABC-type sugar transport system periplasmic component
CSC00_1576	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_1577	COG0842	Transport permease protein
CSC00_1577	COG1129	ABC transporter
CSC00_1578	COG0842	Transport permease protein
CSC00_1585	COG2850	peptidyl-arginine hydroxylation
CSC00_1588	COG5002	protein histidine kinase activity
CSC00_1589	COG0745	RESPONSE REGULATOR receiver
CSC00_1591	COG1538	Outer membrane efflux protein
CSC00_1592	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_1593	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_1594	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC00_1596	COG3040	lipid binding
CSC00_1597	COG0789	Transcriptional regulator
CSC00_1599	COG0300	oxidoreductase activity
CSC00_1602	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSC00_1606	COG3272	Protein of unknown function (DUF1722)
CSC00_1607	COG4580	involved in the transport of maltose and maltodextrins
CSC00_1610	COG2211	Major facilitator Superfamily
CSC00_1611	COG3507	Belongs to the glycosyl hydrolase 43 family
CSC00_1618	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSC00_1618	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CSC00_1619	COG2801	Transposase and inactivated derivatives
CSC00_1621	COG2963	transposase activity
CSC00_1637	COG0582	viral genome integration into host DNA
CSC00_1639	COG0288	reversible hydration of carbon dioxide
CSC00_1640	COG0659	secondary active sulfate transmembrane transporter activity
CSC00_1641	COG1064	alcohol dehydrogenase
CSC00_1643	COG0395	ABC-type sugar transport system, permease component
CSC00_1644	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSC00_1645	COG3842	ATPase activity
CSC00_1646	COG1653	transport
CSC00_1648	COG1082	Xylose isomerase domain protein TIM barrel
CSC00_1650	COG3962	Belongs to the TPP enzyme family
CSC00_1652	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_1653	COG0837	glucose binding
CSC00_1653	COG1737	Transcriptional regulator
CSC00_1655	COG3718	enzyme involved in inositol metabolism
CSC00_1658	COG0433	COG0433 Predicted ATPase
CSC00_1659	COG0795	lipopolysaccharide-transporting ATPase activity
CSC00_1660	COG0795	lipopolysaccharide-transporting ATPase activity
CSC00_1663	COG2927	DNA polymerase III (CHI subunit)
CSC00_1664	COG0525	valine-tRNA ligase activity
CSC00_1667	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CSC00_1669	COG2188	Transcriptional regulator
CSC00_1670	COG1288	antiporter activity
CSC00_1671	COG1228	amidohydrolase
CSC00_1672	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_1673	COG2222	sugar isomerase
CSC00_1675	COG2731	YhcH YjgK YiaL family protein
CSC00_1682	COG1263	PTS System
CSC00_1682	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_1683	COG0366	Alpha amylase catalytic
CSC00_1684	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_1685	COG1486	melibiose metabolic process
CSC00_1689	COG0602	queuosine metabolic process
CSC00_1690	COG2026	Addiction module toxin, RelE StbE family
CSC00_1691	COG3077	Addiction module antitoxin, RelB DinJ family
CSC00_1692	COG3711	transcriptional antiterminator
CSC00_1692	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_1693	COG2706	6-phosphogluconolactonase activity
CSC00_1696	COG3964	amidohydrolase
CSC00_1703	COG3783	Cytochrome b(562)
CSC00_1704	COG0312	modulator of DNA gyrase
CSC00_1710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSC00_1713	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_1714	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_1715	COG1129	ABC transporter
CSC00_1717	COG1879	ABC-type sugar transport system periplasmic component
CSC00_1718	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSC00_1721	COG2105	PFAM AIG2 family protein
CSC00_1722	COG2911	Protein conserved in bacteria
CSC00_1723	COG0729	surface antigen
CSC00_1725	COG1253	flavin adenine dinucleotide binding
CSC00_1727	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CSC00_1730	COG1733	regulation of RNA biosynthetic process
CSC00_1731	COG0702	epimerase
CSC00_1733	COG0697	spore germination
CSC00_1735	COG1113	amino acid transport
CSC00_1736	COG0545	Peptidyl-prolyl cis-trans isomerase
CSC00_1737	COG3061	Opacity-associated protein A
CSC00_1747	COG3414	Phosphotransferase system galactitol-specific IIB component
CSC00_1751	COG1073	alpha beta
CSC00_1752	COG3650	response to hydrogen peroxide
CSC00_1754	COG1960	acyl-CoA dehydrogenase activity
CSC00_1755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC00_1756	COG0557	exoribonuclease II activity
CSC00_1759	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CSC00_1762	COG0330	HflC and HflK could
CSC00_1763	COG0330	HflC and HflK could
CSC00_1764	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSC00_1768	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC00_1769	COG0802	atpase or kinase
CSC00_1770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSC00_1770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSC00_1771	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSC00_1776	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_1780	COG1511	domain protein
CSC00_1780	COG3264	Mechanosensitive ion channel
CSC00_1781	COG0531	amino acid
CSC00_1783	COG1053	succinate dehydrogenase
CSC00_1784	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSC00_1788	COG2076	Multidrug Resistance protein
CSC00_1789	COG5510	response to toxic substance
CSC00_1792	COG1509	lysine 2,3-aminomutase activity
CSC00_1794	COG3039	Transposase
CSC00_1796	COG3121	Chaperone
CSC00_1808	COG0531	amino acid
CSC00_1809	COG3030	protein affecting phage T7 exclusion by the F plasmid
CSC00_1811	COG1027	Aspartate ammonia-lyase
CSC00_1812	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSC00_1815	COG1309	transcriptional regulator
CSC00_1819	COG2801	Transposase and inactivated derivatives
CSC00_1824	COG0457	Tetratricopeptide repeat
CSC00_1825	COG0726	polysaccharide deacetylase
CSC00_1825	COG1649	PFAM Uncharacterised BCR, COG1649
CSC00_1826	COG1215	transferase activity, transferring glycosyl groups
CSC00_1829	COG0861	Integral membrane protein TerC family
CSC00_1834	COG2801	Transposase and inactivated derivatives
CSC00_1839	COG1486	melibiose metabolic process
CSC00_1840	COG2169	Transcriptional regulator
CSC00_1842	COG2824	Alkylphosphonate utilization operon protein PhnA
CSC00_1843	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CSC00_1844	COG2188	Transcriptional regulator
CSC00_1845	COG3624	Phosphonate C-P lyase system protein PhnG
CSC00_1846	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CSC00_1847	COG3626	phosphonate metabolism
CSC00_1848	COG3627	carbon phosphorus lyase activity
CSC00_1849	COG4107	phosphonate C-P lyase system protein PhnK
CSC00_1850	COG4778	phosphonate C-P lyase system protein PhnL
CSC00_1851	COG3454	Phosphonate metabolism
CSC00_1853	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSC00_1855	COG0784	Response regulator, receiver
CSC00_1855	COG4191	Histidine kinase
CSC00_1856	COG1129	ABC transporter
CSC00_1857	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_1858	COG1879	ABC-type sugar transport system periplasmic component
CSC00_1863	COG3383	formate dehydrogenase (NAD+) activity
CSC00_1864	COG3383	formate dehydrogenase (NAD+) activity
CSC00_1865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CSC00_1866	COG1301	dicarboxylic acid transport
CSC00_1868	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSC00_1869	COG3162	membrane
CSC00_1875	COG3539	Fimbrial protein
CSC00_1877	COG1346	cytolysis
CSC00_1878	COG1380	Effector of murein hydrolase LrgA
CSC00_1879	COG0583	DNA-binding transcription factor activity
CSC00_1880	COG0025	NhaP-type Na H and K H
CSC00_1881	COG2252	PERMEase
CSC00_1882	COG0625	glutathione transferase activity
CSC00_1883	COG0789	Transcriptional regulator
CSC00_1885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSC00_1892	COG1234	tRNA 3'-trailer cleavage
CSC00_1893	COG1609	Transcriptional regulator
CSC00_1894	COG0483	inositol monophosphate 1-phosphatase activity
CSC00_1896	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSC00_1901	COG4771	TonB-dependent receptor
CSC00_1903	COG0741	lytic transglycosylase activity
CSC00_1905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSC00_1906	COG2315	Protein conserved in bacteria
CSC00_1907	COG0432	Pfam Uncharacterised protein family UPF0047
CSC00_1910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSC00_1911	COG0305	Participates in initiation and elongation during chromosome replication
CSC00_1914	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSC00_1917	COG0735	belongs to the Fur family
CSC00_1918	COG3237	CsbD-like
CSC00_1920	COG0534	Mate efflux family protein
CSC00_1922	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CSC00_1937	COG0251	oxidation-reduction process
CSC00_1939	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSC00_1941	COG0527	aspartate kinase activity
CSC00_1952	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSC00_1958	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSC00_1960	COG0456	acetyltransferase
CSC00_1966	COG0151	Belongs to the GarS family
CSC00_1968	COG4191	Histidine kinase
CSC00_1969	COG3678	ATP-independent chaperone mediated protein folding
CSC00_1971	COG0776	regulation of translation
CSC00_1972	COG3068	Protein conserved in bacteria
CSC00_1976	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CSC00_1979	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSC00_1980	COG2104	thiamine diphosphate biosynthetic process
CSC00_1984	COG3706	GGDEF domain
CSC00_1986	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSC00_1987	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSC00_1994	COG0250	Participates in transcription elongation, termination and antitermination
CSC00_1995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSC00_2003	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CSC00_2009	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CSC00_2011	COG1739	Uncharacterized protein family UPF0029
CSC00_2020	COG0805	protein transport
CSC00_2022	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSC00_2024	COG3165	ubiquinone biosynthetic process from chorismate
CSC00_2026	COG1322	Protein conserved in bacteria
CSC00_2031	COG0561	phosphatase activity
CSC00_2032	COG2267	carboxylic ester hydrolase activity
CSC00_2033	COG1280	lysine exporter protein (LysE YggA)
CSC00_2035	COG1280	lysine exporter protein (LysE YggA)
CSC00_2038	COG2050	protein possibly involved in aromatic compounds catabolism
CSC00_2040	COG0598	Magnesium transport protein CorA
CSC00_2042	COG0210	DNA helicase
CSC00_2043	COG1011	Hydrolase
CSC00_2047	COG5567	small periplasmic lipoprotein
CSC00_2049	COG3072	Adenylate cyclase
CSC00_2052	COG2959	enzyme of heme biosynthesis
CSC00_2053	COG3071	HemY protein
CSC00_2059	COG1113	amino acid transport
CSC00_2063	COG2244	polysaccharide biosynthetic process
CSC00_2064	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CSC00_2065	COG0456	acetyltransferase
CSC00_2066	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CSC00_2067	COG1088	dTDP-glucose 4,6-dehydratase activity
CSC00_2068	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSC00_2069	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSC00_2071	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSC00_2072	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSC00_2073	COG3118	belongs to the thioredoxin family
CSC00_2077	COG3039	Transposase
CSC00_2078	COG1811	Na channel or pump
CSC00_2080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC00_2081	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSC00_2084	COG0583	DNA-binding transcription factor activity
CSC00_2085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSC00_2087	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSC00_2088	COG3978	acetolactate synthase activity
CSC00_2092	COG3085	chromosome segregation
CSC00_2107	COG0583	DNA-binding transcription factor activity
CSC00_2110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CSC00_2113	COG3443	Belongs to the bacterial solute-binding protein 9 family
CSC00_2114	COG2207	Transcriptional regulator
CSC00_2116	COG0371	Dehydrogenase
CSC00_2117	COG0697	spore germination
CSC00_2119	COG0583	DNA-binding transcription factor activity
CSC00_2121	COG0737	Belongs to the 5'-nucleotidase family
CSC00_2123	COG0527	aspartate kinase activity
CSC00_2123	COG0460	homoserine dehydrogenase
CSC00_2124	COG0626	cystathionine gamma-synthase activity
CSC00_2127	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSC00_2128	COG1609	Transcriptional regulator
CSC00_2129	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSC00_2132	COG1575	Belongs to the MenA family. Type 1 subfamily
CSC00_2136	COG3678	ATP-independent chaperone mediated protein folding
CSC00_2137	COG0745	RESPONSE REGULATOR receiver
CSC00_2138	COG2205	protein histidine kinase activity
CSC00_2139	COG2258	MOSC domain
CSC00_2140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSC00_2147	COG1879	ABC-type sugar transport system periplasmic component
CSC00_2148	COG1129	ABC transporter
CSC00_2149	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_2150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_2151	COG1454	alcohol dehydrogenase
CSC00_2153	COG2211	Major facilitator Superfamily
CSC00_2165	COG0205	6-phosphofructokinase activity
CSC00_2168	COG0243	molybdopterin cofactor binding
CSC00_2168	COG3383	formate dehydrogenase (NAD+) activity
CSC00_2169	COG0243	molybdopterin cofactor binding
CSC00_2169	COG3383	formate dehydrogenase (NAD+) activity
CSC00_2170	COG0437	4 iron, 4 sulfur cluster binding
CSC00_2171	COG2864	formate dehydrogenase
CSC00_2174	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSC00_2176	COG0456	acetyltransferase
CSC00_2179	COG1011	Hydrolase
CSC00_2182	COG0174	glutamine synthetase
CSC00_2183	COG3852	Histidine kinase
CSC00_2185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC00_2190	COG0204	Acyl-transferase
CSC00_2192	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSC00_2193	COG3084	Protein conserved in bacteria
CSC00_2195	COG1763	Mo-molybdopterin cofactor biosynthetic process
CSC00_2200	COG2186	Transcriptional regulator
CSC00_2201	COG0477	Major facilitator Superfamily
CSC00_2202	COG1609	Transcriptional regulator
CSC00_2203	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_2204	COG1879	ABC-type sugar transport system periplasmic component
CSC00_2205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_2212	COG1522	sequence-specific DNA binding
CSC00_2213	COG0716	FMN binding
CSC00_2216	COG3312	ion transport
CSC00_2228	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSC00_2229	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSC00_2230	COG0573	inorganic phosphate transmembrane transporter activity
CSC00_2231	COG0581	inorganic phosphate transmembrane transporter activity
CSC00_2232	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSC00_2233	COG0704	Plays a role in the regulation of phosphate uptake
CSC00_2236	COG2382	esterase
CSC00_2237	COG0363	glucosamine-6-phosphate deaminase activity
CSC00_2238	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC00_2240	COG2252	PERMEase
CSC00_2241	COG0431	NADPH-dependent FMN reductase
CSC00_2242	COG2091	lysine biosynthetic process via aminoadipic acid
CSC00_2253	COG0187	DNA topoisomerase II activity
CSC00_2254	COG0561	phosphatase activity
CSC00_2257	COG2186	Transcriptional regulator
CSC00_2258	COG3734	2-keto-3-deoxy-galactonokinase
CSC00_2259	COG0800	Aldolase
CSC00_2262	COG2271	Major facilitator Superfamily
CSC00_2263	COG0823	Involved in the tonB-independent uptake of proteins
CSC00_2264	COG5645	(Lipo)protein
CSC00_2267	COG3645	SOS response
CSC00_2269	COG2188	Transcriptional regulator
CSC00_2272	COG2149	membrane
CSC00_2276	COG2610	gluconate transmembrane transporter activity
CSC00_2277	COG0583	DNA-binding transcription factor activity
CSC00_2278	COG2814	Major facilitator Superfamily
CSC00_2282	COG0028	Belongs to the TPP enzyme family
CSC00_2283	COG0440	acetolactate synthase activity
CSC00_2284	COG2197	response regulator
CSC00_2286	COG2271	Major facilitator Superfamily
CSC00_2294	COG2188	Transcriptional regulator
CSC00_2300	COG4580	involved in the transport of maltose and maltodextrins
CSC00_2301	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSC00_2302	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_2302	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_2304	COG1609	Transcriptional regulator
CSC00_2306	COG3384	dioxygenase
CSC00_2307	COG0583	DNA-binding transcription factor activity
CSC00_2308	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSC00_2309	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSC00_2310	COG2828	Protein conserved in bacteria
CSC00_2313	COG0697	spore germination
CSC00_2314	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_2314	COG1263	PTS System
CSC00_2316	COG2814	Major facilitator Superfamily
CSC00_2317	COG1538	Outer membrane efflux protein
CSC00_2318	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC00_2327	COG0583	DNA-binding transcription factor activity
CSC00_2332	COG1464	Belongs to the NlpA lipoprotein family
CSC00_2335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CSC00_2337	COG1064	alcohol dehydrogenase
CSC00_2343	COG2211	Major facilitator Superfamily
CSC00_2344	COG1501	Belongs to the glycosyl hydrolase 31 family
CSC00_2346	COG1486	melibiose metabolic process
CSC00_2347	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_2347	COG1263	PTS System
CSC00_2348	COG2982	Protein involved in outer membrane biogenesis
CSC00_2349	COG2233	PERMEase
CSC00_2351	COG0786	glutamate:sodium symporter activity
CSC00_2354	COG3074	FtsZ-dependent cytokinesis
CSC00_2355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSC00_2360	COG3152	Membrane
CSC00_2362	COG1494	fructose-1,6-bisphosphatase
CSC00_2363	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSC00_2364	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC00_2365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSC00_2369	COG2860	membrane
CSC00_2371	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC00_2371	COG2169	Transcriptional regulator
CSC00_2372	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CSC00_2374	COG1561	YicC-like family, N-terminal region
CSC00_2379	COG1131	(ABC) transporter
CSC00_2380	COG3039	Transposase
CSC00_2382	COG0842	Transport permease protein
CSC00_2387	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSC00_2394	COG1519	Transferase
CSC00_2395	COG1216	Glycosyl transferase, family 2
CSC00_2396	COG0438	transferase activity, transferring glycosyl groups
CSC00_2398	COG0859	PFAM glycosyl transferase family 9
CSC00_2403	COG0859	PFAM glycosyl transferase family 9
CSC00_2406	COG0156	8-amino-7-oxononanoate synthase activity
CSC00_2409	COG2861	carbohydrate metabolic process
CSC00_2410	COG4942	peptidase
CSC00_2412	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC00_2413	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSC00_2417	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSC00_2419	COG2186	Transcriptional regulator
CSC00_2423	COG3722	fumarate hydratase activity
CSC00_2427	COG1566	PFAM secretion protein HlyD family protein
CSC00_2428	COG0625	glutathione transferase activity
CSC00_2430	COG3276	selenocysteine insertion sequence binding
CSC00_2431	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSC00_2432	COG3977	Valine--pyruvate aminotransferase
CSC00_2433	COG0366	Alpha amylase catalytic
CSC00_2434	COG2992	FlgJ-related protein
CSC00_2435	COG2207	Transcriptional regulator
CSC00_2435	COG1609	Transcriptional regulator
CSC00_2436	COG4214	carbohydrate transport
CSC00_2437	COG1129	ABC transporter
CSC00_2438	COG4213	ABC transporter substrate-binding protein
CSC00_2441	COG4682	membrane
CSC00_2442	COG4682	membrane
CSC00_2443	COG3274	enterobacterial common antigen metabolic process
CSC00_2450	COG1278	Cold shock
CSC00_2451	COG2944	sequence-specific DNA binding
CSC00_2452	COG2814	Major facilitator Superfamily
CSC00_2456	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_2458	COG1609	Transcriptional regulator
CSC00_2460	COG2885	chlorophyll binding
CSC00_2461	COG0243	molybdopterin cofactor binding
CSC00_2462	COG0456	acetyltransferase
CSC00_2463	COG2818	Glycosylase
CSC00_2464	COG5571	outer membrane autotransporter
CSC00_2465	COG2223	nitrite transmembrane transporter activity
CSC00_2470	COG2801	Transposase and inactivated derivatives
CSC00_2471	COG0747	negative chemotaxis
CSC00_2472	COG0601	transmembrane transport
CSC00_2473	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC00_2474	COG0444	Belongs to the ABC transporter superfamily
CSC00_2475	COG4608	Belongs to the ABC transporter superfamily
CSC00_2480	COG1215	transferase activity, transferring glycosyl groups
CSC00_2481	COG0457	Tetratricopeptide repeat
CSC00_2484	COG2194	sulfuric ester hydrolase activity
CSC00_2490	COG1215	transferase activity, transferring glycosyl groups
CSC00_2491	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CSC00_2492	COG3118	belongs to the thioredoxin family
CSC00_2492	COG0457	Tetratricopeptide repeat
CSC00_2494	COG2199	diguanylate cyclase activity
CSC00_2494	COG2200	EAL domain
CSC00_2496	COG0612	Peptidase, M16
CSC00_2499	COG2982	Protein involved in outer membrane biogenesis
CSC00_2500	COG0477	Major facilitator Superfamily
CSC00_2501	COG1295	ribonuclease BN
CSC00_2502	COG0583	DNA-binding transcription factor activity
CSC00_2503	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_2504	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC00_2506	COG1454	alcohol dehydrogenase
CSC00_2508	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSC00_2509	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSC00_2510	COG0671	phosphoesterase, PA-phosphatase related
CSC00_2514	COG0589	response to stress
CSC00_2516	COG0306	phosphate transporter
CSC00_2517	COG2081	HI0933 family
CSC00_2518	COG2239	Acts as a magnesium transporter
CSC00_2520	COG1124	(ABC) transporter
CSC00_2522	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC00_2523	COG0601	transmembrane transport
CSC00_2524	COG0747	negative chemotaxis
CSC00_2526	COG3479	Phenolic acid decarboxylase
CSC00_2534	COG0628	permease
CSC00_2535	COG0477	Major facilitator Superfamily
CSC00_2537	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CSC00_2540	COG3714	YhhN family
CSC00_2542	COG3776	membrane
CSC00_2543	COG0742	ribosomal rna small subunit methyltransferase
CSC00_2544	COG0552	protein localization to endoplasmic reticulum
CSC00_2545	COG2884	Cell division ATP-binding protein ftsE
CSC00_2546	COG2177	Part of the ABC transporter FtsEX involved in
CSC00_2547	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC00_2549	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC00_2552	COG0683	leucine binding
CSC00_2556	COG0683	leucine binding
CSC00_2557	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC00_2559	COG0411	ABC transporter
CSC00_2560	COG0410	ABC transporter
CSC00_2563	COG1653	transport
CSC00_2567	COG0584	glycerophosphoryl diester phosphodiesterase
CSC00_2569	COG0405	Gamma-glutamyltransferase
CSC00_2570	COG1247	-acetyltransferase
CSC00_2572	COG0673	inositol 2-dehydrogenase activity
CSC00_2573	COG1741	Belongs to the pirin family
CSC00_2574	COG1609	Transcriptional regulator
CSC00_2575	COG3265	gluconokinase activity
CSC00_2576	COG2610	gluconate transmembrane transporter activity
CSC00_2578	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC00_2583	COG0058	SHG alpha-glucan phosphorylase activity
CSC00_2585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSC00_2588	COG1349	DNA-binding transcription factor activity
CSC00_2591	COG0058	SHG alpha-glucan phosphorylase activity
CSC00_2592	COG1640	4-alpha-glucanotransferase
CSC00_2593	COG2610	gluconate transmembrane transporter activity
CSC00_2595	COG1040	competence protein
CSC00_2600	COG1918	ferrous iron import across plasma membrane
CSC00_2601	COG2183	response to ionizing radiation
CSC00_2602	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSC00_2603	COG0745	RESPONSE REGULATOR receiver
CSC00_2608	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSC00_2609	COG1011	Hydrolase
CSC00_2611	COG0494	nUDIX hydrolase
CSC00_2612	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSC00_2617	COG4796	Type ii and iii secretion system protein
CSC00_2620	COG3266	domain, Protein
CSC00_2621	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CSC00_2622	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSC00_2626	COG2146	nitrite reductase [NAD(P)H] activity
CSC00_2627	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSC00_2629	COG0402	S-adenosylhomocysteine deaminase activity
CSC00_2630	COG0738	Major facilitator superfamily
CSC00_2635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSC00_2636	COG1289	transmembrane transporter activity
CSC00_2638	COG1765	OsmC-like protein
CSC00_2639	COG3954	Phosphoribulokinase
CSC00_2641	COG0429	hydrolase of the alpha beta-hydrolase fold
CSC00_2642	COG0488	(ABC) transporter
CSC00_2645	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CSC00_2646	COG1047	Peptidyl-prolyl cis-trans
CSC00_2648	COG0545	Peptidyl-prolyl cis-trans isomerase
CSC00_2649	COG2964	Protein conserved in bacteria
CSC00_2657	COG2906	2 iron, 2 sulfur cluster binding
CSC00_2660	COG0051	transcription antitermination factor activity, RNA binding
CSC00_2668	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSC00_2669	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSC00_2682	COG0201	protein transport
CSC00_2684	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSC00_2686	COG0202	RNA polymerase activity
CSC00_2689	COG0789	Transcriptional regulator
CSC00_2691	COG0569	domain protein
CSC00_2695	COG0758	DNA mediated transformation
CSC00_2697	COG0551	DNA topoisomerase type I activity
CSC00_2701	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSC00_2708	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC00_2709	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_2710	COG1309	transcriptional regulator
CSC00_2711	COG0582	viral genome integration into host DNA
CSC00_2714	COG3561	AntA/AntB antirepressor
CSC00_2733	COG4626	Terminase
CSC00_2733	COG1802	Transcriptional regulator
CSC00_2739	COG4145	pantothenate transmembrane transporter activity
CSC00_2740	COG3924	membrane
CSC00_2741	COG0439	Biotin carboxylase
CSC00_2742	COG0511	ligase activity, forming carbon-carbon bonds
CSC00_2745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSC00_2747	COG2200	EAL domain
CSC00_2747	COG2199	diguanylate cyclase activity
CSC00_2748	COG1077	Cell shape determining protein MreB Mrl
CSC00_2749	COG1792	Involved in formation and maintenance of cell shape
CSC00_2750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CSC00_2752	COG1530	ribonuclease E activity
CSC00_2753	COG3164	Protein of unknown function
CSC00_2754	COG0312	modulator of DNA gyrase
CSC00_2755	COG0583	DNA-binding transcription factor activity
CSC00_2758	COG1289	transmembrane transporter activity
CSC00_2759	COG2732	(Barnase) inhibitor
CSC00_2764	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC00_2765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSC00_2766	COG3105	Protein conserved in bacteria
CSC00_2767	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSC00_2770	COG0625	glutathione transferase activity
CSC00_2771	COG2969	positive regulation of protein catabolic process
CSC00_2773	COG0493	'glutamate synthase
CSC00_2774	COG0067	glutamate synthase
CSC00_2774	COG0069	glutamate synthase activity
CSC00_2774	COG0070	glutamate synthase
CSC00_2775	COG1242	4 iron, 4 sulfur cluster binding
CSC00_2776	COG2271	Major facilitator Superfamily
CSC00_2777	COG1063	alcohol dehydrogenase
CSC00_2779	COG1312	Catalyzes the dehydration of D-mannonate
CSC00_2780	COG0784	Response regulator, receiver
CSC00_2780	COG2198	Histidine kinase
CSC00_2780	COG5002	protein histidine kinase activity
CSC00_2781	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CSC00_2782	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSC00_2783	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2786	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSC00_2787	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSC00_2788	COG1137	ATPase activity
CSC00_2789	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CSC00_2790	COG3117	lipopolysaccharide transmembrane transporter activity
CSC00_2791	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CSC00_2793	COG0530	calcium, potassium:sodium antiporter activity
CSC00_2794	COG1127	ABC transporter
CSC00_2795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSC00_2796	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSC00_2797	COG2854	intermembrane phospholipid transfer
CSC00_2798	COG3113	response to antibiotic
CSC00_2799	COG5007	Belongs to the BolA IbaG family
CSC00_2801	COG3423	Transcriptional regulator
CSC00_2802	COG0142	geranyltranstransferase activity
CSC00_2805	COG0697	spore germination
CSC00_2807	COG2027	D-alanyl-D-alanine carboxypeptidase
CSC00_2808	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSC00_2809	COG1534	Rna-binding protein
CSC00_2811	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSC00_2812	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSC00_2814	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSC00_2824	COG0195	Participates in both transcription termination and antitermination
CSC00_2833	COG0814	amino acid
CSC00_2834	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_2838	COG3153	acetyltransferase
CSC00_2841	COG0693	protein deglycase activity
CSC00_2842	COG0702	epimerase
CSC00_2843	COG0701	Predicted permease
CSC00_2844	COG2823	Periplasmic or secreted lipoprotein
CSC00_2848	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSC00_2851	COG1063	alcohol dehydrogenase
CSC00_2852	COG3775	system Galactitol-specific IIC component
CSC00_2853	COG3414	Phosphotransferase system galactitol-specific IIB component
CSC00_2854	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2856	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2856	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2857	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_2857	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_2857	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_2858	COG1105	Belongs to the carbohydrate kinase PfkB family
CSC00_2861	COG1349	DNA-binding transcription factor activity
CSC00_2862	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_2863	COG2721	sulfolactate sulfo-lyase activity
CSC00_2865	COG2271	Major facilitator Superfamily
CSC00_2867	COG2084	Dehydrogenase
CSC00_2868	COG1929	Belongs to the glycerate kinase type-1 family
CSC00_2873	COG1741	Belongs to the pirin family
CSC00_2874	COG0583	DNA-binding transcription factor activity
CSC00_2875	COG3152	Membrane
CSC00_2876	COG0435	Glutathione S-transferase
CSC00_2877	COG2259	Doxx family
CSC00_2879	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CSC00_2880	COG4575	ribosome binding
CSC00_2881	COG1422	Protein of unknown function (DUF1090)
CSC00_2883	COG0586	Pfam SNARE associated Golgi protein
CSC00_2884	COG2186	Transcriptional regulator
CSC00_2885	COG2271	Major facilitator Superfamily
CSC00_2887	COG2721	sulfolactate sulfo-lyase activity
CSC00_2890	COG0861	Integral membrane protein TerC family
CSC00_2891	COG0673	inositol 2-dehydrogenase activity
CSC00_2892	COG1451	nucleotide metabolic process
CSC00_2896	COG1902	pentaerythritol trinitrate reductase activity
CSC00_2896	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSC00_2906	COG1695	Transcriptional regulator
CSC00_2908	COG2375	cellular response to nickel ion
CSC00_2911	COG1461	Dihydroxyacetone kinase
CSC00_2912	COG2376	Dihydroxyacetone kinase
CSC00_2926	COG3247	response to pH
CSC00_2928	COG0784	Response regulator, receiver
CSC00_2928	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_2928	COG2198	Histidine kinase
CSC00_2928	COG2205	protein histidine kinase activity
CSC00_2929	COG2197	response regulator
CSC00_2934	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC00_2935	COG0358	DNA primase activity
CSC00_2949	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSC00_2952	COG4991	sh3 domain protein
CSC00_2953	COG3025	triphosphatase activity
CSC00_2958	COG2960	long-chain fatty acid transporting porin activity
CSC00_2961	COG3384	dioxygenase
CSC00_2962	COG0754	glutathionylspermidine amidase activity
CSC00_2965	COG0494	nUDIX hydrolase
CSC00_2966	COG3151	Protein conserved in bacteria
CSC00_2967	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSC00_2968	COG3150	esterase
CSC00_2969	COG0187	DNA topoisomerase II activity
CSC00_2970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CSC00_2971	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSC00_2972	COG0642	Histidine kinase
CSC00_2973	COG0745	RESPONSE REGULATOR receiver
CSC00_2974	COG3111	PFAM Bacterial OB fold (BOF) protein
CSC00_2975	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CSC00_2976	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSC00_2977	COG0204	Acyl-transferase
CSC00_2978	COG2132	Multicopper oxidase
CSC00_2979	COG1032	radical SAM domain protein
CSC00_2981	COG0656	L-ascorbic acid biosynthetic process
CSC00_2982	COG1979	alcohol dehydrogenase
CSC00_2983	COG2207	Transcriptional regulator
CSC00_2984	COG0586	Pfam SNARE associated Golgi protein
CSC00_2985	COG0626	cystathionine gamma-synthase activity
CSC00_2987	COG0811	peptide transport
CSC00_2988	COG0848	biopolymer transport protein
CSC00_2989	COG2211	Major facilitator Superfamily
CSC00_2994	COG0625	glutathione transferase activity
CSC00_2997	COG0754	glutathionylspermidine amidase activity
CSC00_2998	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC00_3002	COG0583	DNA-binding transcription factor activity
CSC00_3003	COG0626	cystathionine gamma-synthase activity
CSC00_3011	COG0305	Participates in initiation and elongation during chromosome replication
CSC00_3059	COG3423	Transcriptional regulator
CSC00_3061	COG1278	Cold shock
CSC00_3062	COG3423	Transcriptional regulator
CSC00_3075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSC00_3077	COG1811	Na channel or pump
CSC00_3078	COG1982	Orn Lys Arg decarboxylase major
CSC00_3079	COG2211	Major facilitator Superfamily
CSC00_3082	COG1194	a g-specific adenine glycosylase
CSC00_3084	COG3171	Protein conserved in bacteria
CSC00_3086	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSC00_3089	COG0762	integral membrane protein
CSC00_3090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSC00_3091	COG2805	Type II/IV secretion system protein
CSC00_3096	COG0189	ligase activity
CSC00_3097	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSC00_3098	COG2356	endonuclease I
CSC00_3100	COG2814	Major facilitator Superfamily
CSC00_3107	COG2146	nitrite reductase [NAD(P)H] activity
CSC00_3110	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3111	COG1414	Transcriptional regulator
CSC00_3117	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3118	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CSC00_3122	COG0501	Belongs to the peptidase M48B family
CSC00_3123	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSC00_3126	COG0191	fructose-bisphosphate aldolase activity
CSC00_3127	COG0668	transmembrane transport
CSC00_3129	COG2968	Membrane
CSC00_3133	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSC00_3134	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSC00_3137	COG0006	proline dipeptidase activity
CSC00_3138	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSC00_3139	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSC00_3143	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3144	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC00_3149	COG2723	6-phospho-beta-galactosidase activity
CSC00_3150	COG1737	Transcriptional regulator
CSC00_3152	COG1272	protein, Hemolysin III
CSC00_3154	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CSC00_3156	COG0716	FMN binding
CSC00_3157	COG4974	Belongs to the 'phage' integrase family
CSC00_3159	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSC00_3164	COG4942	peptidase
CSC00_3166	COG2814	Major facilitator Superfamily
CSC00_3169	COG0667	Aldo Keto reductase
CSC00_3176	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSC00_3177	COG1393	Belongs to the ArsC family
CSC00_3178	COG3104	oligopeptide transport
CSC00_3180	COG1538	Outer membrane efflux protein
CSC00_3181	COG1289	transmembrane transporter activity
CSC00_3184	COG3592	Divergent 4Fe-4S mono-cluster
CSC00_3185	COG2388	GCN5-related N-acetyl-transferase
CSC00_3187	COG3539	Fimbrial protein
CSC00_3188	COG3539	Fimbrial protein
CSC00_3189	COG3539	Fimbrial protein
CSC00_3190	COG3188	usher protein
CSC00_3191	COG3121	Chaperone
CSC00_3192	COG3539	Fimbrial protein
CSC00_3195	COG4974	Belongs to the 'phage' integrase family
CSC00_3196	COG3039	Transposase
CSC00_3197	COG4974	Belongs to the 'phage' integrase family
CSC00_3199	COG0582	viral genome integration into host DNA
CSC00_3201	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CSC00_3202	COG1846	Transcriptional regulator
CSC00_3203	COG0697	spore germination
CSC00_3205	COG3039	Transposase
CSC00_3215	COG0667	Aldo Keto reductase
CSC00_3216	COG0814	amino acid
CSC00_3219	COG0183	Belongs to the thiolase family
CSC00_3220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CSC00_3221	COG0823	Involved in the tonB-independent uptake of proteins
CSC00_3223	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3224	COG2814	Major facilitator Superfamily
CSC00_3231	COG3842	ATPase activity
CSC00_3232	COG0395	ABC-type sugar transport system, permease component
CSC00_3233	COG1175	transmembrane transport
CSC00_3234	COG1917	Cupin 2, conserved barrel domain protein
CSC00_3235	COG1794	racemase activity, acting on amino acids and derivatives
CSC00_3236	COG0583	DNA-binding transcription factor activity
CSC00_3237	COG0019	diaminopimelate decarboxylase activity
CSC00_3238	COG1609	Transcriptional regulator
CSC00_3239	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_3240	COG2723	6-phospho-beta-galactosidase activity
CSC00_3241	COG2186	Transcriptional regulator
CSC00_3243	COG1609	Transcriptional regulator
CSC00_3247	COG0667	Aldo Keto reductase
CSC00_3250	COG0861	Integral membrane protein TerC family
CSC00_3257	COG2165	general secretion pathway protein
CSC00_3258	COG4795	General secretion pathway protein
CSC00_3260	COG4967	type IV pilus modification protein PilV
CSC00_3261	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CSC00_3262	COG1025	Belongs to the peptidase M16 family
CSC00_3263	COG1074	ATP-dependent DNA helicase activity
CSC00_3264	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSC00_3266	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSC00_3266	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSC00_3267	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC00_3268	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSC00_3272	COG4810	utilization protein
CSC00_3274	COG4656	Part of a membrane complex involved in electron transport
CSC00_3275	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_3275	COG1454	alcohol dehydrogenase
CSC00_3282	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CSC00_3289	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CSC00_3297	COG2241	protein methyltransferase activity
CSC00_3299	COG2875	Belongs to the precorrin methyltransferase family
CSC00_3315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CSC00_3316	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSC00_3317	COG2166	iron-sulfur cluster assembly
CSC00_3318	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSC00_3320	COG0583	DNA-binding transcription factor activity
CSC00_3321	COG2363	Small membrane protein
CSC00_3323	COG1349	DNA-binding transcription factor activity
CSC00_3327	COG0738	Major facilitator superfamily
CSC00_3329	COG0235	Class ii aldolase
CSC00_3330	COG1454	alcohol dehydrogenase
CSC00_3334	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_3337	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSC00_3338	COG2011	ABC-type metal ion transport system permease component
CSC00_3339	COG1464	Belongs to the NlpA lipoprotein family
CSC00_3340	COG0477	Major facilitator Superfamily
CSC00_3342	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC00_3343	COG1760	l-serine dehydratase
CSC00_3344	COG0814	amino acid
CSC00_3345	COG1611	Belongs to the LOG family
CSC00_3348	COG3098	single-species biofilm formation
CSC00_3349	COG0564	pseudouridine synthase activity
CSC00_3350	COG0716	FMN binding
CSC00_3351	COG2271	Major facilitator Superfamily
CSC00_3352	COG4948	Mandelate Racemase Muconate Lactonizing
CSC00_3353	COG4948	Mandelate Racemase Muconate Lactonizing
CSC00_3354	COG1929	Belongs to the glycerate kinase type-1 family
CSC00_3355	COG2205	protein histidine kinase activity
CSC00_3355	COG3437	response regulator, receiver
CSC00_3355	COG3850	Histidine kinase
CSC00_3355	COG4999	Histidine kinase
CSC00_3357	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSC00_3358	COG3956	TIGRFAM MazG family protein
CSC00_3363	COG0602	queuosine metabolic process
CSC00_3364	COG0720	synthase
CSC00_3369	COG2234	aminopeptidase activity
CSC00_3381	COG4942	peptidase
CSC00_3381	COG1388	LysM domain
CSC00_3382	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSC00_3387	COG0163	prenyltransferase activity
CSC00_3388	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSC00_3395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_3396	COG4558	Periplasmic binding protein
CSC00_3397	COG3720	iron ion transport
CSC00_3401	COG0679	Auxin Efflux Carrier
CSC00_3404	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC00_3405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC00_3406	COG1121	(ABC) transporter
CSC00_3407	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC00_3408	COG1609	Transcriptional regulator
CSC00_3409	COG1940	carbohydrate kinase activity
CSC00_3410	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSC00_3411	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_3412	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_3413	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSC00_3414	COG4580	involved in the transport of maltose and maltodextrins
CSC00_3416	COG2723	6-phospho-beta-galactosidase activity
CSC00_3418	COG0309	Hydrogenase expression formation protein (HypE)
CSC00_3419	COG0409	Hydrogenase expression formation protein
CSC00_3420	COG0298	carbon dioxide binding
CSC00_3421	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CSC00_3425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSC00_3426	COG0651	ATP synthesis coupled electron transport
CSC00_3427	COG0650	Formate hydrogenlyase subunit 4
CSC00_3428	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CSC00_3428	COG3261	NADH dehydrogenase
CSC00_3429	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSC00_3430	COG3260	NADH ubiquinone oxidoreductase 20
CSC00_3432	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CSC00_3435	COG2723	6-phospho-beta-galactosidase activity
CSC00_3436	COG1263	PTS System
CSC00_3436	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_3439	COG1609	Transcriptional regulator
CSC00_3440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSC00_3441	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CSC00_3442	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CSC00_3448	COG1349	DNA-binding transcription factor activity
CSC00_3449	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_3450	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3452	COG3732	PTS system glucitol sorbitol-specific
CSC00_3453	COG3730	PTS system glucitol sorbitol-specific
CSC00_3454	COG2951	lytic endotransglycosylase activity
CSC00_3455	COG1121	(ABC) transporter
CSC00_3456	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC00_3457	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSC00_3458	COG1546	Belongs to the CinA family
CSC00_3470	COG2823	Periplasmic or secreted lipoprotein
CSC00_3471	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC00_3472	COG1238	metal cluster binding
CSC00_3476	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSC00_3477	COG2814	Major facilitator Superfamily
CSC00_3478	COG1566	PFAM secretion protein HlyD family protein
CSC00_3480	COG1846	Transcriptional regulator
CSC00_3482	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSC00_3484	COG4176	ABC-type proline glycine betaine transport system permease component
CSC00_3487	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSC00_3490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC00_3491	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC00_3492	COG4575	ribosome binding
CSC00_3496	COG2916	Histone family protein nucleoid-structuring protein H-NS
CSC00_3499	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSC00_3500	COG0640	Transcriptional regulator
CSC00_3502	COG0583	DNA-binding transcription factor activity
CSC00_3503	COG3284	Transcriptional regulator
CSC00_3504	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_3507	COG3539	Fimbrial protein
CSC00_3508	COG3121	Chaperone
CSC00_3512	COG3188	usher protein
CSC00_3514	COG3539	Fimbrial protein
CSC00_3515	COG2197	response regulator
CSC00_3518	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_3520	COG0235	Class ii aldolase
CSC00_3522	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_3530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_3531	COG3708	Transcriptional regulator
CSC00_3531	COG2207	Transcriptional regulator
CSC00_3537	COG2867	negative regulation of translational initiation
CSC00_3541	COG0497	DNA recombination
CSC00_3544	COG4536	flavin adenine dinucleotide binding
CSC00_3545	COG4137	Cytochrome C assembly protein
CSC00_3546	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSC00_3554	COG2885	chlorophyll binding
CSC00_3555	COG2199	diguanylate cyclase activity
CSC00_3557	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSC00_3558	COG0287	Prephenate dehydrogenase
CSC00_3558	COG1605	Chorismate mutase
CSC00_3560	COG0077	Prephenate dehydratase
CSC00_3560	COG1605	Chorismate mutase
CSC00_3561	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSC00_3562	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSC00_3563	COG0564	pseudouridine synthase activity
CSC00_3566	COG0542	response to heat
CSC00_3573	COG0477	Major facilitator Superfamily
CSC00_3574	COG5544	Lipoprotein
CSC00_3575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSC00_3578	COG3118	belongs to the thioredoxin family
CSC00_3579	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSC00_3582	COG0513	Belongs to the DEAD box helicase family
CSC00_3584	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CSC00_3586	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CSC00_3587	COG3026	antisigma factor binding
CSC00_3588	COG3086	response to oxidative stress
CSC00_3590	COG0681	Belongs to the peptidase S26 family
CSC00_3594	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSC00_3596	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSC00_3597	COG1737	Transcriptional regulator
CSC00_3598	COG0560	Phosphoserine phosphatase
CSC00_3599	COG0590	tRNA wobble adenosine to inosine editing
CSC00_3601	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSC00_3601	COG0047	phosphoribosylformylglycinamidine synthase activity
CSC00_3602	COG2205	protein histidine kinase activity
CSC00_3603	COG3170	Tfp pilus assembly protein FimV
CSC00_3604	COG2204	response regulator
CSC00_3605	COG0347	Belongs to the P(II) protein family
CSC00_3606	COG1017	nitric oxide dioxygenase activity
CSC00_3606	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC00_3608	COG2259	Doxx family
CSC00_3609	COG1940	carbohydrate kinase activity
CSC00_3610	COG0457	Tetratricopeptide repeat
CSC00_3611	COG2814	Major facilitator Superfamily
CSC00_3611	COG0477	Major facilitator Superfamily
CSC00_3612	COG2017	converts alpha-aldose to the beta-anomer
CSC00_3613	COG2814	Major facilitator Superfamily
CSC00_3614	COG3711	transcriptional antiterminator
CSC00_3615	COG3683	transport system, periplasmic component
CSC00_3616	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CSC00_3623	COG0822	iron-sulfur transferase activity
CSC00_3627	COG0633	Ferredoxin
CSC00_3628	COG2975	iron-sulfur cluster assembly
CSC00_3632	COG2897	thiosulfate sulfurtransferase activity
CSC00_3633	COG2373	Large extracellular alpha-helical protein
CSC00_3634	COG4953	penicillin-binding protein 1C
CSC00_3641	COG2976	Protein conserved in bacteria
CSC00_3645	COG1645	bacterial-type flagellum-dependent swarming motility
CSC00_3648	COG0516	GMP reductase activity
CSC00_3648	COG0517	IMP dehydrogenase activity
CSC00_3651	COG0641	radical SAM
CSC00_3655	COG2200	EAL domain
CSC00_3656	COG0248	Ppx GppA phosphatase
CSC00_3658	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSC00_3661	COG2723	6-phospho-beta-galactosidase activity
CSC00_3663	COG2233	PERMEase
CSC00_3666	COG1393	Belongs to the ArsC family
CSC00_3667	COG4783	chaperone-mediated protein folding
CSC00_3669	COG0628	permease
CSC00_3670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSC00_3671	COG2716	regulation of RNA biosynthetic process
CSC00_3673	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CSC00_3675	COG2321	neutral zinc metallopeptidase
CSC00_3676	COG1444	tRNA N-acetyltransferase activity
CSC00_3677	COG0400	carboxylic ester hydrolase activity
CSC00_3680	COG1393	Belongs to the ArsC family
CSC00_3681	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSC00_3682	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSC00_3682	COG0493	'glutamate synthase
CSC00_3684	COG5342	invasion associated locus B
CSC00_3685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSC00_3686	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSC00_3688	COG4810	utilization protein
CSC00_3689	COG4917	ethanolamine utilization protein
CSC00_3696	COG4820	ethanolamine utilization protein (EutJ)
CSC00_3702	COG4816	utilization protein
CSC00_3706	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSC00_3710	COG2837	iron assimilation
CSC00_3711	COG4150	thiosulfate binding
CSC00_3712	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CSC00_3713	COG4208	sulfate ABC transporter
CSC00_3714	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSC00_3716	COG4319	ketosteroid isomerase
CSC00_3720	COG2190	(PTS) system
CSC00_3723	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSC00_3728	COG3530	Putative quorum-sensing-regulated virulence factor
CSC00_3729	COG0385	Bile acid
CSC00_3730	COG0583	DNA-binding transcription factor activity
CSC00_3737	COG3415	Transposase
CSC00_3738	COG3415	Transposase
CSC00_3741	COG2199	diguanylate cyclase activity
CSC00_3741	COG2200	EAL domain
CSC00_3742	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSC00_3745	COG0667	Aldo Keto reductase
CSC00_3746	COG3961	Belongs to the TPP enzyme family
CSC00_3749	COG3279	Response regulator of the LytR AlgR family
CSC00_3750	COG3275	phosphorelay sensor kinase activity
CSC00_3752	COG0436	Aminotransferase
CSC00_3753	COG2807	transmembrane transport
CSC00_3754	COG0590	tRNA wobble adenosine to inosine editing
CSC00_3755	COG0583	DNA-binding transcription factor activity
CSC00_3760	COG2116	formate transmembrane transporter activity
CSC00_3761	COG2853	Lipoprotein
CSC00_3763	COG3691	Protein conserved in bacteria
CSC00_3766	COG2062	phosphohistidine phosphatase, SixA
CSC00_3768	COG2890	protein-(glutamine-N5) methyltransferase activity
CSC00_3771	COG0730	response to heat
CSC00_3772	COG3101	peptidyl-lysine hydroxylation
CSC00_3775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC00_3780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC00_3782	COG0586	Pfam SNARE associated Golgi protein
CSC00_3784	COG0285	dihydrofolate synthase activity
CSC00_3785	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CSC00_3786	COG1286	toxin biosynthetic process
CSC00_3787	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSC00_3788	COG0163	prenyltransferase activity
CSC00_3790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSC00_3792	COG4215	(ABC) transporter
CSC00_3793	COG4160	amino acid transport
CSC00_3794	COG4598	ABC transporter
CSC00_3797	COG1090	epimerase
CSC00_3798	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSC00_3799	COG0625	glutathione transferase activity
CSC00_3800	COG0625	glutathione transferase activity
CSC00_3801	COG0622	Phosphoesterase
CSC00_3802	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CSC00_3803	COG0280	phosphate acetyltransferase
CSC00_3803	COG0857	belongs to the CobB CobQ family
CSC00_3804	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSC00_3809	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC00_3810	COG0471	metal ion transport
CSC00_3810	COG0490	domain, Protein
CSC00_3812	COG0436	Aminotransferase
CSC00_3814	COG0583	DNA-binding transcription factor activity
CSC00_3819	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CSC00_3821	COG1034	ATP synthesis coupled electron transport
CSC00_3824	COG0839	Belongs to the complex I subunit 6 family
CSC00_3826	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSC00_3827	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSC00_3830	COG2153	protein acetylation
CSC00_3831	COG1169	isochorismate synthase
CSC00_3836	COG0318	PFAM AMP-dependent synthetase and ligase
CSC00_3839	COG5464	transposase or invertase
CSC00_3843	COG1414	Transcriptional regulator
CSC00_3846	COG2271	Major facilitator Superfamily
CSC00_3848	COG0247	lactate metabolic process
CSC00_3850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSC00_3851	COG2271	Major facilitator Superfamily
CSC00_3852	COG0584	glycerophosphoryl diester phosphodiesterase
CSC00_3853	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC00_3858	COG2205	protein histidine kinase activity
CSC00_3858	COG0784	Response regulator, receiver
CSC00_3860	COG0642	Histidine kinase
CSC00_3860	COG2198	Histidine kinase
CSC00_3864	COG2169	Transcriptional regulator
CSC00_3864	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC00_3865	COG3145	DNA-N1-methyladenine dioxygenase activity
CSC00_3866	COG4615	Cyclic peptide transporter
CSC00_3867	COG2239	Acts as a magnesium transporter
CSC00_3868	COG0659	secondary active sulfate transmembrane transporter activity
CSC00_3871	COG0628	permease
CSC00_3876	COG1349	DNA-binding transcription factor activity
CSC00_3877	COG0494	nUDIX hydrolase
CSC00_3881	COG1061	Type III restriction enzyme res subunit
CSC00_3882	COG1187	pseudouridine synthase activity
CSC00_3883	COG2814	Major facilitator Superfamily
CSC00_3885	COG4172	Belongs to the ABC transporter superfamily
CSC00_3886	COG4239	(ABC) transporter, permease
CSC00_3887	COG4174	ABC transporter (Permease)
CSC00_3888	COG4166	transmembrane transport
CSC00_3889	COG2200	EAL domain
CSC00_3890	COG0791	NLP P60 protein
CSC00_3893	COG0671	phosphoesterase, PA-phosphatase related
CSC00_3894	COG0523	cobalamin synthesis protein
CSC00_3895	COG0246	Mannitol dehydrogenase
CSC00_3896	COG1312	Catalyzes the dehydration of D-mannonate
CSC00_3901	COG1105	Belongs to the carbohydrate kinase PfkB family
CSC00_3902	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_3902	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_3902	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSC00_3904	COG2855	membrane
CSC00_3906	COG0583	DNA-binding transcription factor activity
CSC00_3907	COG0833	amino acid
CSC00_3909	COG4771	TonB-dependent receptor
CSC00_3912	COG2311	Membrane
CSC00_3917	COG2949	membrane
CSC00_3919	COG1346	cytolysis
CSC00_3921	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSC00_3923	COG3659	wide pore channel activity
CSC00_3926	COG2723	6-phospho-beta-galactosidase activity
CSC00_3928	COG1538	Outer membrane efflux protein
CSC00_3929	COG0586	Pfam SNARE associated Golgi protein
CSC00_3931	COG1686	Belongs to the peptidase S11 family
CSC00_3933	COG0277	FAD linked oxidase domain protein
CSC00_3934	COG1472	Belongs to the glycosyl hydrolase 3 family
CSC00_3935	COG1732	Glycine betaine
CSC00_3936	COG1174	glycine betaine transport
CSC00_3937	COG1125	glycine betaine transport
CSC00_3938	COG1174	glycine betaine transport
CSC00_3940	COG3275	phosphorelay sensor kinase activity
CSC00_3942	COG4807	Protein conserved in bacteria
CSC00_3947	COG5455	response to cobalt ion
CSC00_3948	COG0583	DNA-binding transcription factor activity
CSC00_3949	COG2252	PERMEase
CSC00_3951	COG0583	DNA-binding transcription factor activity
CSC00_3952	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CSC00_3954	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CSC00_3957	COG0351	phosphomethylpyrimidine kinase
CSC00_3958	COG1830	Aldolase
CSC00_3966	COG1070	Carbohydrate kinase
CSC00_3968	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSC00_3970	COG2801	Transposase and inactivated derivatives
CSC00_3973	COG0745	RESPONSE REGULATOR receiver
CSC00_3974	COG2205	protein histidine kinase activity
CSC00_3979	COG1301	dicarboxylic acid transport
CSC00_3983	COG5002	protein histidine kinase activity
CSC00_3984	COG0443	Heat shock 70 kDa protein
CSC00_3985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSC00_3988	COG2982	Protein involved in outer membrane biogenesis
CSC00_3989	COG1253	flavin adenine dinucleotide binding
CSC00_3999	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSC00_4004	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CSC00_4005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC00_4006	COG1051	belongs to the nudix hydrolase family
CSC00_4007	COG0297	glycogen (starch) synthase activity
CSC00_4021	COG0438	transferase activity, transferring glycosyl groups
CSC00_4022	COG1442	glycosyl transferase family 8
CSC00_4022	COG1216	Glycosyl transferase, family 2
CSC00_4024	COG0463	Glycosyl transferase, family 2
CSC00_4029	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSC00_4034	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSC00_4035	COG0583	DNA-binding transcription factor activity
CSC00_4036	COG0531	amino acid
CSC00_4037	COG0640	Transcriptional regulator
CSC00_4038	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSC00_4039	COG2925	Exonuclease
CSC00_4041	COG3344	reverse transcriptase
CSC00_4043	COG1289	transmembrane transporter activity
CSC00_4047	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSC00_4049	COG1942	4-Oxalocrotonate Tautomerase
CSC00_4050	COG0583	DNA-binding transcription factor activity
CSC00_4051	COG0095	Lipoate-protein ligase
CSC00_4052	COG0477	Major facilitator Superfamily
CSC00_4054	COG3300	MHYT domain
CSC00_4054	COG5001	Diguanylate cyclase
CSC00_4056	COG3615	Tellurite resistance protein tehB
CSC00_4061	COG3706	GGDEF domain
CSC00_4070	COG2916	Histone family protein nucleoid-structuring protein H-NS
CSC00_4093	COG0582	viral genome integration into host DNA
CSC00_4096	COG0534	Mate efflux family protein
CSC00_4098	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSC00_4102	COG0604	alcohol dehydrogenase
CSC00_4103	COG1309	transcriptional regulator
CSC00_4104	COG0025	NhaP-type Na H and K H
CSC00_4111	COG0251	oxidation-reduction process
CSC00_4115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSC00_4117	COG1418	mRNA catabolic process
CSC00_4118	COG0270	DNA (cytosine-5-)-methyltransferase activity
CSC00_4119	COG3727	T/G mismatch-specific endonuclease activity
CSC00_4120	COG0697	spore germination
CSC00_4121	COG2354	Protein conserved in bacteria
CSC00_4127	COG0366	Alpha amylase catalytic
CSC00_4132	COG2197	response regulator
CSC00_4134	COG2197	response regulator
CSC00_4136	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSC00_4141	COG3012	SEC-C Motif Domain Protein
CSC00_4141	COG3318	Belongs to the UPF0149 family
CSC00_4142	COG0814	amino acid
CSC00_4144	COG1528	Iron-storage protein
CSC00_4147	COG0477	Major facilitator Superfamily
CSC00_4149	COG2211	Major facilitator Superfamily
CSC00_4151	COG1528	Iron-storage protein
CSC00_4153	COG1879	ABC-type sugar transport system periplasmic component
CSC00_4155	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_4160	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CSC00_4162	COG3102	Protein conserved in bacteria
CSC00_4166	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CSC00_4167	COG1801	Protein of unknown function DUF72
CSC00_4168	COG1335	isochorismatase
CSC00_4170	COG0494	nUDIX hydrolase
CSC00_4175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSC00_4177	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CSC00_4178	COG0739	heme binding
CSC00_4179	COG1560	Kdo2-lipid A biosynthetic process
CSC00_4181	COG1737	Transcriptional regulator
CSC00_4184	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSC00_4185	COG0129	dihydroxy-acid dehydratase activity
CSC00_4186	COG0800	Aldolase
CSC00_4188	COG3141	response to X-ray
CSC00_4189	COG2979	Protein of unknown function (DUF533)
CSC00_4190	COG1770	oligopeptidase
CSC00_4191	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSC00_4193	COG2372	response to copper ion
CSC00_4194	COG1276	copper resistance
CSC00_4197	COG2990	Protein conserved in bacteria
CSC00_4202	COG3008	intermembrane lipid transfer
CSC00_4203	COG2995	paraquat-inducible protein a
CSC00_4204	COG1956	GAF domain-containing protein
CSC00_4208	COG2814	Major facilitator Superfamily
CSC00_4209	COG1414	Transcriptional regulator
CSC00_4214	COG1278	Cold shock
CSC00_4215	COG0768	penicillin binding
CSC00_4216	COG2226	methyltransferase
CSC00_4219	COG3716	PTS system mannose fructose sorbose family IID component
CSC00_4220	COG3715	PTS system
CSC00_4221	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_4221	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_4222	COG1253	flavin adenine dinucleotide binding
CSC00_4223	COG2200	EAL domain
CSC00_4224	COG1760	l-serine dehydratase
CSC00_4228	COG0251	oxidation-reduction process
CSC00_4229	COG1199	ATP-dependent helicase activity
CSC00_4231	COG3065	identical protein binding
CSC00_4232	COG0318	PFAM AMP-dependent synthetase and ligase
CSC00_4233	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CSC00_4235	COG2894	cell division
CSC00_4238	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSC00_4245	COG2719	SpoVR family
CSC00_4250	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSC00_4252	COG4774	siderophore transport
CSC00_4254	COG2308	Evidence 4 Homologs of previously reported genes of
CSC00_4263	COG0583	DNA-binding transcription factor activity
CSC00_4264	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSC00_4267	COG1882	Formate acetyltransferase
CSC00_4269	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC00_4272	COG0410	ABC transporter
CSC00_4273	COG0583	DNA-binding transcription factor activity
CSC00_4279	COG0583	DNA-binding transcription factor activity
CSC00_4282	COG3122	Protein conserved in bacteria
CSC00_4287	COG2885	chlorophyll binding
CSC00_4289	COG3501	Rhs element vgr protein
CSC00_4303	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSC00_4309	COG3039	Transposase
CSC00_4323	COG0012	GTP binding
CSC00_4328	COG0659	secondary active sulfate transmembrane transporter activity
CSC00_4329	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSC00_4334	COG2890	protein-(glutamine-N5) methyltransferase activity
CSC00_4335	COG3094	Invasion gene expression up-regulator, SirB
CSC00_4336	COG2912	Transglutaminase-like superfamily
CSC00_4338	COG0387	Pfam Sodium calcium exchanger
CSC00_4339	COG4572	Cation transport regulator
CSC00_4340	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CSC00_4343	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CSC00_4344	COG3707	response regulator
CSC00_4345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC00_4347	COG1116	anion transmembrane transporter activity
CSC00_4348	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSC00_4348	COG2146	nitrite reductase [NAD(P)H] activity
CSC00_4349	COG0243	molybdopterin cofactor binding
CSC00_4350	COG4932	domain protein
CSC00_4351	COG2197	response regulator
CSC00_4352	COG3850	Histidine kinase
CSC00_4353	COG2223	nitrite transmembrane transporter activity
CSC00_4355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSC00_4356	COG1140	nitrate reductase beta subunit
CSC00_4357	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CSC00_4358	COG2181	nitrate reductase activity
CSC00_4360	COG1522	sequence-specific DNA binding
CSC00_4363	COG0788	formyltetrahydrofolate deformylase activity
CSC00_4365	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSC00_4366	COG0745	RESPONSE REGULATOR receiver
CSC00_4367	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSC00_4368	COG2916	Histone family protein nucleoid-structuring protein H-NS
CSC00_4370	COG1435	thymidine kinase activity
CSC00_4371	COG1454	alcohol dehydrogenase
CSC00_4371	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_4373	COG2095	MarC family integral membrane protein
CSC00_4375	COG4166	transmembrane transport
CSC00_4376	COG0601	transmembrane transport
CSC00_4377	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC00_4378	COG0444	Belongs to the ABC transporter superfamily
CSC00_4380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC00_4385	COG2353	YceI-like domain
CSC00_4386	COG2350	Protein conserved in bacteria
CSC00_4390	COG1105	Belongs to the carbohydrate kinase PfkB family
CSC00_4391	COG3137	Salt-induced outer membrane protein
CSC00_4398	COG0072	phenylalanine-tRNA ligase activity
CSC00_4398	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSC00_4402	COG0583	DNA-binding transcription factor activity
CSC00_4406	COG0386	Belongs to the glutathione peroxidase family
CSC00_4408	COG0791	NLP P60 protein
CSC00_4410	COG4256	Hemin uptake protein
CSC00_4411	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSC00_4414	COG0574	Belongs to the PEP-utilizing enzyme family
CSC00_4414	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSC00_4415	COG0628	permease
CSC00_4417	COG0247	lactate metabolic process
CSC00_4417	COG0277	FAD linked oxidase domain protein
CSC00_4418	COG2050	protein possibly involved in aromatic compounds catabolism
CSC00_4419	COG2261	transglycosylase associated protein
CSC00_4425	COG1120	ATPase activity
CSC00_4426	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_4428	COG0583	DNA-binding transcription factor activity
CSC00_4433	COG1304	FMN binding
CSC00_4434	COG1309	transcriptional regulator
CSC00_4438	COG0316	Belongs to the HesB IscA family
CSC00_4439	COG0719	Fe-S assembly protein
CSC00_4440	COG0396	ATPase activity
CSC00_4441	COG0719	Fe-S assembly protein
CSC00_4445	COG1376	ErfK ybiS ycfS ynhG family protein
CSC00_4451	COG1309	transcriptional regulator
CSC00_4453	COG2271	Major facilitator Superfamily
CSC00_4454	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSC00_4459	COG1414	Transcriptional regulator
CSC00_4466	COG2814	Major facilitator Superfamily
CSC00_4470	COG0583	DNA-binding transcription factor activity
CSC00_4471	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_4475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC00_4476	COG1116	anion transmembrane transporter activity
CSC00_4477	COG4774	siderophore transport
CSC00_4478	COG1120	ATPase activity
CSC00_4479	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_4480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_4485	COG0765	amino acid transport
CSC00_4486	COG1126	abc transporter atp-binding protein
CSC00_4489	COG2814	Major facilitator Superfamily
CSC00_4492	COG1473	amidohydrolase
CSC00_4493	COG3383	formate dehydrogenase (NAD+) activity
CSC00_4494	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CSC00_4496	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC00_4497	COG1175	transmembrane transport
CSC00_4505	COG4133	protoheme IX ABC transporter activity
CSC00_4506	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC00_4507	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSC00_4510	COG1138	Cytochrome C-type biogenesis protein
CSC00_4511	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSC00_4512	COG3088	subunit of a heme lyase
CSC00_4512	COG4235	cytochrome complex assembly
CSC00_4514	COG2207	Transcriptional regulator
CSC00_4515	COG0656	L-ascorbic acid biosynthetic process
CSC00_4523	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_4524	COG2610	gluconate transmembrane transporter activity
CSC00_4525	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC00_4527	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSC00_4529	COG0583	DNA-binding transcription factor activity
CSC00_4534	COG0277	FAD linked oxidase domain protein
CSC00_4535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC00_4540	COG0402	S-adenosylhomocysteine deaminase activity
CSC00_4542	COG0583	DNA-binding transcription factor activity
CSC00_4551	COG4608	Belongs to the ABC transporter superfamily
CSC00_4552	COG0444	Belongs to the ABC transporter superfamily
CSC00_4557	COG0346	lactoylglutathione lyase activity
CSC00_4558	COG1349	DNA-binding transcription factor activity
CSC00_4565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CSC00_4570	COG3039	Transposase
CSC00_4577	COG0307	riboflavin synthase, alpha
CSC00_4578	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSC00_4579	COG2814	Major facilitator Superfamily
CSC00_4581	COG2814	Major facilitator Superfamily
CSC00_4582	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSC00_4584	COG0791	NLP P60 protein
CSC00_4585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSC00_4587	COG0346	lactoylglutathione lyase activity
CSC00_4588	COG1902	pentaerythritol trinitrate reductase activity
CSC00_4589	COG1309	transcriptional regulator
CSC00_4590	COG3313	Fe-S protein
CSC00_4591	COG4989	oxidoreductase activity
CSC00_4592	COG2032	superoxide dismutase activity
CSC00_4593	COG1289	transmembrane transporter activity
CSC00_4594	COG1566	PFAM secretion protein HlyD family protein
CSC00_4597	COG3706	GGDEF domain
CSC00_4598	COG3133	Outer membrane lipoprotein
CSC00_4600	COG3895	Periplasmic Protein
CSC00_4603	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CSC00_4604	COG0625	glutathione transferase activity
CSC00_4607	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSC00_4609	COG4659	FMN binding
CSC00_4616	COG2723	6-phospho-beta-galactosidase activity
CSC00_4617	COG0673	inositol 2-dehydrogenase activity
CSC00_4619	COG2814	Major facilitator Superfamily
CSC00_4620	COG1733	regulation of RNA biosynthetic process
CSC00_4623	COG3038	cytochrome b561
CSC00_4628	COG0583	DNA-binding transcription factor activity
CSC00_4630	COG3485	protocatechuate 3,4-dioxygenase
CSC00_4631	COG3485	protocatechuate 3,4-dioxygenase
CSC00_4632	COG5383	Protein conserved in bacteria
CSC00_4633	COG2272	Belongs to the type-B carboxylesterase lipase family
CSC00_4636	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC00_4637	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSC00_4638	COG1275	C4-dicarboxylate transporter malic acid transport protein
CSC00_4639	COG0500	methyltransferase
CSC00_4643	COG3708	Transcriptional regulator
CSC00_4643	COG2207	Transcriptional regulator
CSC00_4644	COG3135	benzoate transporter
CSC00_4645	COG1396	sequence-specific DNA binding
CSC00_4647	COG0826	peptidase U32
CSC00_4651	COG1294	oxidase, subunit
CSC00_4652	COG1271	oxidase subunit
CSC00_4653	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSC00_4654	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSC00_4655	COG3842	ATPase activity
CSC00_4656	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSC00_4657	COG1177	transmembrane transport
CSC00_4658	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_4663	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_4665	COG0747	negative chemotaxis
CSC00_4667	COG3238	Protein conserved in bacteria
CSC00_4668	COG1247	-acetyltransferase
CSC00_4670	COG2130	NADP-dependent
CSC00_4673	COG3691	Protein conserved in bacteria
CSC00_4674	COG1228	amidohydrolase
CSC00_4675	COG4772	TonB-dependent receptor
CSC00_4680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSC00_4681	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_4683	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_4686	COG0765	amino acid transport
CSC00_4687	COG1126	abc transporter atp-binding protein
CSC00_4689	COG0625	glutathione transferase activity
CSC00_4692	COG2211	Major facilitator Superfamily
CSC00_4695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSC00_4696	COG3842	ATPase activity
CSC00_4697	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC00_4698	COG1178	ABC-type Fe3 transport system permease component
CSC00_4699	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CSC00_4700	COG2181	nitrate reductase activity
CSC00_4701	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CSC00_4702	COG1140	nitrate reductase beta subunit
CSC00_4703	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSC00_4707	COG1414	Transcriptional regulator
CSC00_4708	COG4948	Mandelate Racemase Muconate Lactonizing
CSC00_4709	COG4829	muconolactone delta-isomerase
CSC00_4710	COG3485	protocatechuate 3,4-dioxygenase
CSC00_4712	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSC00_4716	COG0243	molybdopterin cofactor binding
CSC00_4716	COG3383	formate dehydrogenase (NAD+) activity
CSC00_4717	COG0243	molybdopterin cofactor binding
CSC00_4717	COG3383	formate dehydrogenase (NAD+) activity
CSC00_4718	COG0437	4 iron, 4 sulfur cluster binding
CSC00_4719	COG2864	formate dehydrogenase
CSC00_4722	COG2326	polyphosphate kinase activity
CSC00_4724	COG2814	Major facilitator Superfamily
CSC00_4726	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSC00_4730	COG0747	negative chemotaxis
CSC00_4731	COG1064	alcohol dehydrogenase
CSC00_4735	COG0488	(ABC) transporter
CSC00_4743	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_4744	COG3729	General stress protein
CSC00_4746	COG3685	Protein conserved in bacteria
CSC00_4748	COG0366	Alpha amylase catalytic
CSC00_4750	COG2323	membrane
CSC00_4752	COG3039	Transposase
CSC00_4753	COG3111	PFAM Bacterial OB fold (BOF) protein
CSC00_4755	COG1764	response to oxidative stress
CSC00_4758	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSC00_4759	COG3781	membrane
CSC00_4760	COG0243	molybdopterin cofactor binding
CSC00_4761	COG0583	DNA-binding transcription factor activity
CSC00_4762	COG2814	Major facilitator Superfamily
CSC00_4763	COG1285	pathogenesis
CSC00_4764	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSC00_4766	COG0583	DNA-binding transcription factor activity
CSC00_4770	COG0519	Catalyzes the synthesis of GMP from XMP
CSC00_4770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSC00_4777	COG0596	Alpha beta hydrolase
CSC00_4778	COG0745	RESPONSE REGULATOR receiver
CSC00_4779	COG2205	protein histidine kinase activity
CSC00_4782	COG0076	glutamate decarboxylase activity
CSC00_4783	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSC00_4784	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSC00_4785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSC00_4786	COG1116	anion transmembrane transporter activity
CSC00_4787	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSC00_4789	COG0673	inositol 2-dehydrogenase activity
CSC00_4792	COG3706	GGDEF domain
CSC00_4793	COG0402	S-adenosylhomocysteine deaminase activity
CSC00_4794	COG1953	Uracil, thiamine, allantoin
CSC00_4804	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSC00_4807	COG2207	Transcriptional regulator
CSC00_4810	COG0583	DNA-binding transcription factor activity
CSC00_4813	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSC00_4817	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSC00_4829	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSC00_4831	COG2070	2-Nitropropane dioxygenase
CSC00_4832	COG0583	DNA-binding transcription factor activity
CSC00_4834	COG1902	pentaerythritol trinitrate reductase activity
CSC00_4835	COG4529	Protein conserved in bacteria
CSC00_4836	COG0477	Major facilitator Superfamily
CSC00_4842	COG2223	nitrite transmembrane transporter activity
CSC00_4844	COG1609	Transcriptional regulator
CSC00_4845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_4847	COG3037	sugar-specific permease SgaT UlaA
CSC00_4848	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSC00_4851	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_4852	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSC00_4852	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_4852	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSC00_4855	COG0583	DNA-binding transcription factor activity
CSC00_4856	COG0583	DNA-binding transcription factor activity
CSC00_4857	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSC00_4859	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSC00_4862	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSC00_4864	COG1609	Transcriptional regulator
CSC00_4870	COG1652	LysM domain
CSC00_4872	COG1840	ABC-type Fe3 transport system, periplasmic component
CSC00_4875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSC00_4875	COG0456	acetyltransferase
CSC00_4878	COG0667	Aldo Keto reductase
CSC00_4879	COG0667	Aldo Keto reductase
CSC00_4880	COG3386	PFAM SMP-30 Gluconolaconase
CSC00_4881	COG0667	Aldo Keto reductase
CSC00_4883	COG2801	Transposase and inactivated derivatives
CSC00_4887	COG4977	sequence-specific DNA binding
CSC00_4891	COG4977	sequence-specific DNA binding
CSC00_4892	COG1349	DNA-binding transcription factor activity
CSC00_4895	COG1349	DNA-binding transcription factor activity
CSC00_4896	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSC00_4897	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSC00_4898	COG0738	Major facilitator superfamily
CSC00_4907	COG1929	Belongs to the glycerate kinase type-1 family
CSC00_4908	COG3835	regulator
CSC00_4912	COG2186	Transcriptional regulator
CSC00_4913	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_4913	COG1263	PTS System
CSC00_4916	COG2814	Major facilitator Superfamily
CSC00_4917	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_4917	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSC00_4920	COG2819	hydrolase of the alpha beta superfamily
CSC00_4921	COG5001	Diguanylate cyclase
CSC00_4921	COG3300	MHYT domain
CSC00_4924	COG0024	Methionine aminopeptidase
CSC00_4928	COG3188	usher protein
CSC00_4931	COG3550	peptidyl-serine autophosphorylation
CSC00_4932	COG1396	sequence-specific DNA binding
CSC00_4933	COG2351	hydroxyisourate hydrolase activity
CSC00_4934	COG3195	allantoin biosynthetic process
CSC00_4934	COG3648	Uricase
CSC00_4935	COG2233	PERMEase
CSC00_4941	COG4644	lycopene metabolic process
CSC00_4944	COG2207	Transcriptional regulator
CSC00_4947	COG4628	conserved protein (DUF2132)
CSC00_4951	COG2011	ABC-type metal ion transport system permease component
CSC00_4952	COG2070	2-Nitropropane dioxygenase
CSC00_4954	COG0477	Major facilitator Superfamily
CSC00_4956	COG0477	Major facilitator Superfamily
CSC00_4968	COG2199	diguanylate cyclase activity
CSC00_4971	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_4972	COG0583	DNA-binding transcription factor activity
CSC00_4974	COG0039	L-malate dehydrogenase activity
CSC00_4975	COG1349	DNA-binding transcription factor activity
CSC00_4976	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSC00_4977	COG3395	kinase activity
CSC00_4979	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSC00_4982	COG2731	YhcH YjgK YiaL family protein
CSC00_4983	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_4988	COG1846	Transcriptional regulator
CSC00_4989	COG4977	sequence-specific DNA binding
CSC00_4991	COG0697	spore germination
CSC00_4992	COG2814	Major facilitator Superfamily
CSC00_4994	COG0410	ABC transporter
CSC00_4995	COG1129	ABC transporter
CSC00_4997	COG0559	Belongs to the binding-protein-dependent transport system permease family
CSC00_4998	COG0683	leucine binding
CSC00_4999	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CSC00_5007	COG2223	nitrite transmembrane transporter activity
CSC00_5008	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CSC00_5011	COG1349	DNA-binding transcription factor activity
CSC00_5012	COG2084	Dehydrogenase
CSC00_5013	COG3395	kinase activity
CSC00_5014	COG0235	Class ii aldolase
CSC00_5015	COG3622	Belongs to the hyi family
CSC00_5016	COG2610	gluconate transmembrane transporter activity
CSC00_5017	COG3708	Transcriptional regulator
CSC00_5017	COG2207	Transcriptional regulator
CSC00_5018	COG3039	Transposase
CSC00_5021	COG2200	EAL domain
CSC00_5022	COG1546	Belongs to the CinA family
CSC00_5023	COG0071	Belongs to the small heat shock protein (HSP20) family
CSC00_5025	COG2197	response regulator
CSC00_5028	COG2135	peptidase activity
CSC00_5029	COG2207	Transcriptional regulator
CSC00_5033	COG4221	oxidoreductase activity
CSC00_5034	COG1802	Transcriptional regulator
CSC00_5035	COG0589	response to stress
CSC00_5036	COG0246	Mannitol dehydrogenase
CSC00_5037	COG2271	Major facilitator Superfamily
CSC00_5040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSC00_5043	COG0243	molybdopterin cofactor binding
CSC00_5044	COG0437	4 iron, 4 sulfur cluster binding
CSC00_5045	COG3302	dmso reductase anchor subunit
CSC00_5048	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CSC00_5049	COG1940	carbohydrate kinase activity
CSC00_5050	COG0583	DNA-binding transcription factor activity
CSC00_5051	COG2814	Major facilitator Superfamily
CSC00_5052	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CSC00_5055	COG3591	Belongs to the peptidase S1B family
CSC00_5059	COG0628	permease
CSC00_5065	COG0679	Auxin Efflux Carrier
CSC00_5067	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSC00_5072	COG3290	protein histidine kinase activity
CSC00_5073	COG4565	transcriptional regulatory protein
CSC00_5075	COG1053	succinate dehydrogenase
CSC00_5078	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC00_5078	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC00_5080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSC00_5081	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSC00_5083	COG0183	Belongs to the thiolase family
CSC00_5084	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSC00_5086	COG1414	Transcriptional regulator
CSC00_5087	COG2840	Smr protein MutS2
CSC00_5088	COG0583	DNA-binding transcription factor activity
CSC00_5090	COG1473	amidohydrolase
CSC00_5091	COG1473	amidohydrolase
CSC00_5092	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CSC00_5094	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSC00_5095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSC00_5098	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CSC00_5099	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSC00_5103	COG0531	amino acid
CSC00_5105	COG3136	membrane protein required for alginate biosynthesis
CSC00_5106	COG0745	RESPONSE REGULATOR receiver
CSC00_5108	COG2205	protein histidine kinase activity
CSC00_5110	COG0114	fumarate hydratase activity
CSC00_5111	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC00_5111	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSC00_5112	COG1482	cell wall glycoprotein biosynthetic process
CSC00_5113	COG5339	Protein conserved in bacteria
CSC00_5114	COG1609	Transcriptional regulator
CSC00_5115	COG1263	PTS System
CSC00_5115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSC00_5116	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CSC00_5121	COG2391	methyltransferase activity
CSC00_5122	COG0425	Belongs to the sulfur carrier protein TusA family
CSC00_5123	COG5562	phage envelope protein
CSC00_5124	COG0401	homolog of Blt101
CSC00_5125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSC00_5126	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_5128	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CSC00_5129	COG0477	Major facilitator Superfamily
CSC00_5130	COG1113	amino acid transport
CSC00_5131	COG2988	succinylglutamate desuccinylase activity
CSC00_5132	COG3724	N-succinylarginine dihydrolase activity
CSC00_5133	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_5134	COG3138	arginine N-succinyltransferase
CSC00_5135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSC00_5138	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSC00_5139	COG0667	Aldo Keto reductase
CSC00_5140	COG0583	DNA-binding transcription factor activity
CSC00_5144	COG1538	Outer membrane efflux protein
CSC00_5146	COG1643	Atp-dependent helicase
CSC00_5149	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSC00_5150	COG3327	negative regulation of DNA-templated transcription, initiation
CSC00_5151	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CSC00_5152	COG0183	Belongs to the thiolase family
CSC00_5153	COG2050	protein possibly involved in aromatic compounds catabolism
CSC00_5154	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSC00_5155	COG1024	Enoyl-CoA hydratase
CSC00_5156	COG1024	Enoyl-CoA hydratase
CSC00_5157	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSC00_5158	COG2151	metal-sulfur cluster biosynthetic enzyme
CSC00_5159	COG3396	Phenylacetate-CoA oxygenase
CSC00_5160	COG3460	Phenylacetate-CoA oxygenase
CSC00_5161	COG3396	Phenylacetate-CoA oxygenase
CSC00_5162	COG2030	dehydratase
CSC00_5162	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_5166	COG1012	belongs to the aldehyde dehydrogenase family
CSC00_5167	COG2207	Transcriptional regulator
CSC00_5168	COG3784	Protein of unknown function (DUF1318)
CSC00_5170	COG2911	Protein conserved in bacteria
CSC00_5171	COG0586	Pfam SNARE associated Golgi protein
CSC00_5172	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSC00_5173	COG3187	Heat shock protein
CSC00_5174	COG3042	response to heat
CSC00_5175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSC00_5175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSC00_5175	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSC00_5175	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSC00_5176	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSC00_5178	COG0589	response to stress
CSC00_5180	COG0513	Belongs to the DEAD box helicase family
CSC00_5182	COG1349	DNA-binding transcription factor activity
CSC00_5183	COG0673	inositol 2-dehydrogenase activity
CSC00_5186	COG1113	amino acid transport
CSC00_5187	COG1522	sequence-specific DNA binding
CSC00_5189	COG1448	Aminotransferase
CSC00_5190	COG2011	ABC-type metal ion transport system permease component
CSC00_5193	COG0436	Aminotransferase
CSC00_5199	COG0583	DNA-binding transcription factor activity
CSC00_5203	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_5204	COG1309	transcriptional regulator
CSC00_5205	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_5226	COG2885	chlorophyll binding
CSC00_5249	COG0739	heme binding
CSC00_5249	COG0741	lytic transglycosylase activity
CSC00_5249	COG1196	nuclear chromosome segregation
CSC00_5264	COG3567	Phage-associated protein, HI1409 family
CSC00_5265	COG1783	phage Terminase large subunit
CSC00_5268	COG3772	lysozyme
CSC00_5272	COG0484	heat shock protein binding
CSC00_5290	COG0582	viral genome integration into host DNA
CSC00_5291	COG0693	protein deglycase activity
CSC00_5292	COG1078	dGTPase activity
CSC00_5293	COG1028	Short-chain dehydrogenase reductase Sdr
CSC00_5294	COG0583	DNA-binding transcription factor activity
CSC00_5297	COG0656	L-ascorbic acid biosynthetic process
CSC00_5303	COG4166	transmembrane transport
CSC00_5305	COG2866	Carboxypeptidase
CSC00_5306	COG4948	Mandelate Racemase Muconate Lactonizing
CSC00_5307	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSC00_5308	COG3180	Ammonia monooxygenase
CSC00_5309	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CSC00_5310	COG1486	melibiose metabolic process
CSC00_5311	COG0583	DNA-binding transcription factor activity
CSC00_5313	COG3106	COG3106 Predicted ATPase
CSC00_5315	COG1983	PspC domain protein
CSC00_5317	COG1842	Phage shock protein A
CSC00_5318	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSC00_5320	COG1473	amidohydrolase
CSC00_5323	COG0702	epimerase
CSC00_5325	COG4168	peptide transport system, permease
CSC00_5326	COG2135	peptidase activity
CSC00_5329	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSC00_5330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSC00_5331	COG3344	reverse transcriptase
CSC00_5339	COG3300	MHYT domain
CSC00_5339	COG5001	Diguanylate cyclase
CSC00_5345	COG3677	Transposase
CSC00_5346	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CSC00_5356	COG3316	Transposase and inactivated derivatives
CSC00_5362	COG3344	reverse transcriptase
CSC00_5363	COG3677	Transposase
CSC00_5363	COG1662	PFAM IS1 transposase
CSC00_5378	COG3328	transposase activity
CSC00_5379	COG3039	Transposase
CSC00_5381	COG4221	oxidoreductase activity
CSC00_5383	COG3316	Transposase and inactivated derivatives
CSC00_5386	COG3316	Transposase and inactivated derivatives
CSC00_5392	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSC00_5398	COG5433	transposase activity
CSC00_5408	COG2205	protein histidine kinase activity
CSC00_5409	COG0745	RESPONSE REGULATOR receiver
CSC00_5410	COG1276	copper resistance
CSC00_5411	COG2372	response to copper ion
CSC00_5412	COG3667	copper resistance
CSC00_5413	COG2132	Multicopper oxidase
CSC00_5415	COG0739	heme binding
CSC00_5421	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSC00_5429	COG2963	transposase activity
CSC00_5430	COG2801	Transposase and inactivated derivatives
CSC00_5431	COG1662	PFAM IS1 transposase
CSC00_5432	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSC00_5433	COG4325	translation initiation factor activity
CSC00_5434	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSC00_5436	COG2203	Gaf domain
CSC00_5436	COG2199	diguanylate cyclase activity
CSC00_5439	COG1192	Involved in chromosome partitioning
CSC00_5440	COG1475	DNA binding
CSC00_5442	COG0675	Transposase, IS605 OrfB family
CSC00_5443	COG0675	Transposase, IS605 OrfB family
CSC00_5447	COG3344	reverse transcriptase
CSC00_5458	COG1475	DNA binding
CSC00_5468	COG5499	transcription regulator containing HTH domain
CSC00_5514	COG2223	nitrite transmembrane transporter activity
CSC00_5516	COG1609	Transcriptional regulator
CSC00_5521	COG3436	PFAM IS66 Orf2 family protein
CSC00_5522	COG1120	ATPase activity
CSC00_5523	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_5524	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSC00_5525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSC00_5526	COG4772	TonB-dependent receptor
CSC00_5527	COG3712	iron ion homeostasis
CSC00_5528	COG1595	DNA-templated transcription, initiation
CSC00_5533	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSC00_5534	COG0601	transmembrane transport
CSC00_5537	COG4172	Belongs to the ABC transporter superfamily
CSC00_5538	COG4372	Transposase
CSC00_5539	COG4372	Transposase
CSC00_5540	COG2433	Pfam Transposase IS66
CSC00_5541	COG3436	PFAM IS66 Orf2 family protein
CSC00_5545	COG1662	PFAM IS1 transposase
CSC00_5559	COG1695	Transcriptional regulator
CSC00_5560	COG3316	Transposase and inactivated derivatives
CSC00_5563	COG3173	Aminoglycoside phosphotransferase
CSC00_5564	COG3316	Transposase and inactivated derivatives
CSC00_5566	COG3316	Transposase and inactivated derivatives
CSC00_5568	COG3316	Transposase and inactivated derivatives
CSC00_5575	COG3039	Transposase
CSC00_5576	COG3039	Transposase
CSC00_5577	COG1662	PFAM IS1 transposase
CSC00_5577	COG3677	Transposase
CSC00_5580	COG0071	Belongs to the small heat shock protein (HSP20) family
CSC00_5581	COG0542	response to heat
CSC00_5584	COG0501	Belongs to the peptidase M48B family
CSC00_5587	COG2801	Transposase and inactivated derivatives
CSC00_5597	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSC00_5604	COG0431	NADPH-dependent FMN reductase
CSC00_5607	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSC00_5635	COG0210	DNA helicase
CSC00_5648	COG3344	reverse transcriptase
CSC00_5660	COG3316	Transposase and inactivated derivatives
CSC00_5668	COG2916	Histone family protein nucleoid-structuring protein H-NS
CSC00_5673	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSC00_5700	COG3344	reverse transcriptase
CSC00_5702	COG0675	Transposase, IS605 OrfB family
CSC00_5737	COG1484	DNA-dependent DNA replication
CSC00_5761	COG4644	lycopene metabolic process
CSC00_5775	COG3316	Transposase and inactivated derivatives
CSC00_5792	COG3941	tape measure
CSC00_5808	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSC00_5809	COG1475	DNA binding
CSC00_5828	COG0237	dephospho-CoA kinase activity
CSC00_5831	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CSC00_5848	COG3316	Transposase and inactivated derivatives
CSC00_5852	COG1702	phosphate starvation-inducible protein PhoH
CSC00_5853	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSC00_5865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSC00_5867	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CSC00_5883	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSC00_5898	COG0629	single-stranded DNA binding