locus-tag	class	description
HH204_00005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HH204_00010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HH204_00015	COG0768	penicillin binding
HH204_00035	COG1609	Transcriptional regulator
HH204_00095	COG0738	Major facilitator superfamily
HH204_00110	COG2271	Major facilitator Superfamily
HH204_00115	COG2814	Major facilitator Superfamily
HH204_00140	COG1178	ABC-type Fe3 transport system permease component
HH204_00150	COG0586	Pfam SNARE associated Golgi protein
HH204_00175	COG0235	Class ii aldolase
HH204_00180	COG0417	DNA replication proofreading
HH204_00190	COG0564	pseudouridine synthase activity
HH204_00200	COG3493	citrate carrier protein
HH204_00215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HH204_00220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HH204_00230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HH204_00275	COG0505	Belongs to the CarA family
HH204_00345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HH204_00370	COG1047	Peptidyl-prolyl cis-trans
HH204_00385	COG0196	riboflavin kinase activity
HH204_00405	COG0583	DNA-binding transcription factor activity
HH204_00430	COG4735	regulation of single-species biofilm formation
HH204_00435	COG1584	GPR1 FUN34 yaaH family protein
HH204_00440	COG0477	Major facilitator Superfamily
HH204_00445	COG0521	Mo-molybdopterin cofactor biosynthetic process
HH204_00450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HH204_00455	COG1115	amino acid carrier protein
HH204_00470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HH204_00480	COG0527	aspartate kinase activity
HH204_00480	COG0460	homoserine dehydrogenase
HH204_00495	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HH204_00505	COG0745	RESPONSE REGULATOR receiver
HH204_00510	COG4452	Inner membrane protein CreD
HH204_00515	COG2205	protein histidine kinase activity
HH204_00520	COG0745	RESPONSE REGULATOR receiver
HH204_00525	COG3045	CreA protein
HH204_00530	COG3708	Transcriptional regulator
HH204_00530	COG2207	Transcriptional regulator
HH204_00550	COG0741	lytic transglycosylase activity
HH204_00555	COG0488	(ABC) transporter
HH204_00565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HH204_00570	COG0560	Phosphoserine phosphatase
HH204_00575	COG3726	membrane protein affecting hemolysin expression
HH204_00605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HH204_00610	COG0084	hydrolase, TatD family'
HH204_00615	COG4667	esterase of the alpha-beta hydrolase superfamily
HH204_00625	COG2823	Periplasmic or secreted lipoprotein
HH204_00635	COG1011	Hydrolase
HH204_00640	COG0456	acetyltransferase
HH204_00645	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HH204_00680	COG3706	GGDEF domain
HH204_00685	COG4114	ferric iron reductase
HH204_00690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_00690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_00695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HH204_00700	COG2197	response regulator
HH204_00705	COG2197	response regulator
HH204_00720	COG2966	Psort location CytoplasmicMembrane, score
HH204_00735	COG1484	DNA-dependent DNA replication
HH204_00750	COG5464	transposase or invertase
HH204_00760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HH204_00765	COG3716	PTS system mannose fructose sorbose family IID component
HH204_00770	COG3715	PTS system
HH204_00785	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HH204_00785	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HH204_00795	COG1063	alcohol dehydrogenase
HH204_00800	COG1802	Transcriptional regulator
HH204_00805	COG2271	Major facilitator Superfamily
HH204_00810	COG0456	acetyltransferase
HH204_00810	COG1214	PFAM Peptidase M22, glycoprotease
HH204_00820	COG1737	Transcriptional regulator
HH204_00825	COG0800	Aldolase
HH204_00830	COG3734	2-keto-3-deoxy-galactonokinase
HH204_00845	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HH204_00875	COG1846	Transcriptional regulator
HH204_00885	COG0179	Fumarylacetoacetate (FAA) hydrolase
HH204_00895	COG1012	belongs to the aldehyde dehydrogenase family
HH204_00900	COG3384	dioxygenase
HH204_00910	COG3971	2-oxopent-4-enoate hydratase activity
HH204_00930	COG2368	4-hydroxyphenylacetate
HH204_00935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HH204_00960	COG1966	Carbon starvation protein
HH204_00965	COG2879	small protein
HH204_00970	COG0523	cobalamin synthesis protein
HH204_00980	COG1012	belongs to the aldehyde dehydrogenase family
HH204_00985	COG5464	transposase or invertase
HH204_00990	COG1917	Cupin 2, conserved barrel domain protein
HH204_00990	COG2207	Transcriptional regulator
HH204_01000	COG2733	membrane
HH204_01015	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HH204_01020	COG1924	4 iron, 4 sulfur cluster binding
HH204_01035	COG1566	PFAM secretion protein HlyD family protein
HH204_01045	COG5457	Domain of unknown function (DUF1127)
HH204_01050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HH204_01065	COG0583	DNA-binding transcription factor activity
HH204_01070	COG2249	NAD(P)H dehydrogenase (quinone) activity
HH204_01080	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_01085	COG1129	ABC transporter
HH204_01090	COG1879	ABC-type sugar transport system periplasmic component
HH204_01100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_01105	COG0842	Transport permease protein
HH204_01105	COG1129	ABC transporter
HH204_01110	COG0842	Transport permease protein
HH204_01140	COG2850	peptidyl-arginine hydroxylation
HH204_01155	COG5002	protein histidine kinase activity
HH204_01160	COG0745	RESPONSE REGULATOR receiver
HH204_01165	COG1538	Outer membrane efflux protein
HH204_01170	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_01175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_01180	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HH204_01190	COG3040	lipid binding
HH204_01195	COG0789	Transcriptional regulator
HH204_01205	COG0300	oxidoreductase activity
HH204_01220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HH204_01240	COG3272	Protein of unknown function (DUF1722)
HH204_01245	COG4580	involved in the transport of maltose and maltodextrins
HH204_01255	COG2115	Belongs to the xylose isomerase family
HH204_01260	COG2211	Major facilitator Superfamily
HH204_01265	COG3507	Belongs to the glycosyl hydrolase 43 family
HH204_01285	COG1216	Glycosyl transferase, family 2
HH204_01345	COG2003	Belongs to the UPF0758 family
HH204_01370	COG2378	regulation of single-species biofilm formation
HH204_01375	COG3596	GTP binding
HH204_01390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HH204_01465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HH204_01490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HH204_01500	COG0582	viral genome integration into host DNA
HH204_01510	COG0288	reversible hydration of carbon dioxide
HH204_01515	COG0659	secondary active sulfate transmembrane transporter activity
HH204_01520	COG1064	alcohol dehydrogenase
HH204_01525	COG1175	transmembrane transport
HH204_01530	COG0395	ABC-type sugar transport system, permease component
HH204_01535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HH204_01540	COG3842	ATPase activity
HH204_01555	COG1082	Xylose isomerase domain protein TIM barrel
HH204_01565	COG3962	Belongs to the TPP enzyme family
HH204_01575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_01580	COG0837	glucose binding
HH204_01580	COG1737	Transcriptional regulator
HH204_01585	COG3718	enzyme involved in inositol metabolism
HH204_01600	COG0433	COG0433 Predicted ATPase
HH204_01605	COG0795	lipopolysaccharide-transporting ATPase activity
HH204_01610	COG0795	lipopolysaccharide-transporting ATPase activity
HH204_01620	COG2927	DNA polymerase III (CHI subunit)
HH204_01625	COG0525	valine-tRNA ligase activity
HH204_01650	COG2188	Transcriptional regulator
HH204_01655	COG1288	antiporter activity
HH204_01660	COG1228	amidohydrolase
HH204_01665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_01670	COG2222	sugar isomerase
HH204_01680	COG2731	YhcH YjgK YiaL family protein
HH204_01715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_01715	COG1263	PTS System
HH204_01720	COG0366	Alpha amylase catalytic
HH204_01725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_01730	COG1486	melibiose metabolic process
HH204_01755	COG0602	queuosine metabolic process
HH204_01760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_01760	COG3711	transcriptional antiterminator
HH204_01765	COG2706	6-phosphogluconolactonase activity
HH204_01780	COG3964	amidohydrolase
HH204_01820	COG0312	modulator of DNA gyrase
HH204_01850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HH204_01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_01865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_01870	COG1129	ABC transporter
HH204_01875	COG1879	ABC-type sugar transport system periplasmic component
HH204_01890	COG2105	PFAM AIG2 family protein
HH204_01895	COG2911	Protein conserved in bacteria
HH204_01900	COG0729	surface antigen
HH204_01910	COG1253	flavin adenine dinucleotide binding
HH204_01935	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HH204_01950	COG1733	regulation of RNA biosynthetic process
HH204_01955	COG0702	epimerase
HH204_01965	COG0697	spore germination
HH204_01975	COG1113	amino acid transport
HH204_01980	COG0545	Peptidyl-prolyl cis-trans isomerase
HH204_01985	COG3061	Opacity-associated protein A
HH204_01995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HH204_02000	COG2965	DNA replication, synthesis of RNA primer
HH204_02060	COG1073	alpha beta
HH204_02065	COG3650	response to hydrogen peroxide
HH204_02075	COG1960	acyl-CoA dehydrogenase activity
HH204_02080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HH204_02085	COG0557	exoribonuclease II activity
HH204_02100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HH204_02110	COG0330	HflC and HflK could
HH204_02115	COG0330	HflC and HflK could
HH204_02120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HH204_02145	COG0860	N-Acetylmuramoyl-L-alanine amidase
HH204_02150	COG0802	atpase or kinase
HH204_02155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HH204_02155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HH204_02160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HH204_02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_02200	COG1511	domain protein
HH204_02200	COG3264	Mechanosensitive ion channel
HH204_02215	COG1053	succinate dehydrogenase
HH204_02220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HH204_02240	COG2076	Multidrug Resistance protein
HH204_02245	COG5510	response to toxic substance
HH204_02260	COG1509	lysine 2,3-aminomutase activity
HH204_02325	COG0531	amino acid
HH204_02330	COG3030	protein affecting phage T7 exclusion by the F plasmid
HH204_02335	COG1027	Aspartate ammonia-lyase
HH204_02340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HH204_02355	COG1309	transcriptional regulator
HH204_02390	COG0457	Tetratricopeptide repeat
HH204_02395	COG0726	polysaccharide deacetylase
HH204_02395	COG1649	PFAM Uncharacterised BCR, COG1649
HH204_02400	COG1215	transferase activity, transferring glycosyl groups
HH204_02420	COG0861	Integral membrane protein TerC family
HH204_02460	COG1486	melibiose metabolic process
HH204_02465	COG2169	Transcriptional regulator
HH204_02475	COG2824	Alkylphosphonate utilization operon protein PhnA
HH204_02480	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HH204_02485	COG2188	Transcriptional regulator
HH204_02490	COG3624	Phosphonate C-P lyase system protein PhnG
HH204_02495	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HH204_02500	COG3626	phosphonate metabolism
HH204_02505	COG3627	carbon phosphorus lyase activity
HH204_02510	COG4107	phosphonate C-P lyase system protein PhnK
HH204_02515	COG4778	phosphonate C-P lyase system protein PhnL
HH204_02520	COG3454	Phosphonate metabolism
HH204_02530	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HH204_02540	COG0784	Response regulator, receiver
HH204_02540	COG4191	Histidine kinase
HH204_02545	COG1129	ABC transporter
HH204_02550	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_02585	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HH204_02590	COG1301	dicarboxylic acid transport
HH204_02600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HH204_02605	COG3162	membrane
HH204_02635	COG3539	Fimbrial protein
HH204_02645	COG1346	cytolysis
HH204_02650	COG1380	Effector of murein hydrolase LrgA
HH204_02655	COG0583	DNA-binding transcription factor activity
HH204_02660	COG0025	NhaP-type Na H and K H
HH204_02665	COG2252	PERMEase
HH204_02670	COG0625	glutathione transferase activity
HH204_02675	COG0789	Transcriptional regulator
HH204_02685	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HH204_02715	COG1234	tRNA 3'-trailer cleavage
HH204_02720	COG1609	Transcriptional regulator
HH204_02725	COG0483	inositol monophosphate 1-phosphatase activity
HH204_02735	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HH204_02760	COG4771	TonB-dependent receptor
HH204_02775	COG0741	lytic transglycosylase activity
HH204_02790	COG2315	Protein conserved in bacteria
HH204_02795	COG0432	Pfam Uncharacterised protein family UPF0047
HH204_02810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HH204_02815	COG0305	Participates in initiation and elongation during chromosome replication
HH204_02830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HH204_02840	COG0735	belongs to the Fur family
HH204_02845	COG3237	CsbD-like
HH204_02855	COG0534	Mate efflux family protein
HH204_02865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HH204_02890	COG4580	involved in the transport of maltose and maltodextrins
HH204_02935	COG0251	oxidation-reduction process
HH204_02945	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HH204_02955	COG0527	aspartate kinase activity
HH204_03005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HH204_03015	COG0456	acetyltransferase
HH204_03045	COG0151	Belongs to the GarS family
HH204_03055	COG4191	Histidine kinase
HH204_03060	COG3678	ATP-independent chaperone mediated protein folding
HH204_03095	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HH204_03110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HH204_03115	COG2104	thiamine diphosphate biosynthetic process
HH204_03130	COG3706	GGDEF domain
HH204_03140	COG1447	Phosphotransferase system cellobiose-specific component IIA
HH204_03145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HH204_03180	COG0250	Participates in transcription elongation, termination and antitermination
HH204_03225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HH204_03255	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HH204_03265	COG1739	Uncharacterized protein family UPF0029
HH204_03310	COG0805	protein transport
HH204_03330	COG3165	ubiquinone biosynthetic process from chorismate
HH204_03360	COG0583	DNA-binding transcription factor activity
HH204_03365	COG0697	spore germination
HH204_03370	COG0561	phosphatase activity
HH204_03375	COG2267	carboxylic ester hydrolase activity
HH204_03380	COG1280	lysine exporter protein (LysE YggA)
HH204_03390	COG1280	lysine exporter protein (LysE YggA)
HH204_03420	COG0210	DNA helicase
HH204_03425	COG1011	Hydrolase
HH204_03455	COG3072	Adenylate cyclase
HH204_03470	COG2959	enzyme of heme biosynthesis
HH204_03475	COG3071	HemY protein
HH204_03525	COG2244	polysaccharide biosynthetic process
HH204_03530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HH204_03535	COG0456	acetyltransferase
HH204_03540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HH204_03545	COG1088	dTDP-glucose 4,6-dehydratase activity
HH204_03550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HH204_03555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HH204_03565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HH204_03570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HH204_03575	COG3118	belongs to the thioredoxin family
HH204_03600	COG1811	Na channel or pump
HH204_03610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HH204_03615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HH204_03625	COG0583	DNA-binding transcription factor activity
HH204_03630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HH204_03645	COG3978	acetolactate synthase activity
HH204_03665	COG3085	chromosome segregation
HH204_03740	COG0583	DNA-binding transcription factor activity
HH204_03755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HH204_03770	COG3443	Belongs to the bacterial solute-binding protein 9 family
HH204_03775	COG2207	Transcriptional regulator
HH204_03785	COG0371	Dehydrogenase
HH204_03790	COG0697	spore germination
HH204_03800	COG0583	DNA-binding transcription factor activity
HH204_03810	COG0737	Belongs to the 5'-nucleotidase family
HH204_03820	COG0527	aspartate kinase activity
HH204_03820	COG0460	homoserine dehydrogenase
HH204_03825	COG0626	cystathionine gamma-synthase activity
HH204_03840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HH204_03845	COG1609	Transcriptional regulator
HH204_03850	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HH204_03865	COG1575	Belongs to the MenA family. Type 1 subfamily
HH204_03885	COG3678	ATP-independent chaperone mediated protein folding
HH204_03890	COG0745	RESPONSE REGULATOR receiver
HH204_03895	COG2205	protein histidine kinase activity
HH204_03900	COG2258	MOSC domain
HH204_03905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HH204_03945	COG1129	ABC transporter
HH204_03950	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_03955	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_03960	COG1454	alcohol dehydrogenase
HH204_03970	COG2211	Major facilitator Superfamily
HH204_04015	COG0437	4 iron, 4 sulfur cluster binding
HH204_04020	COG2864	formate dehydrogenase
HH204_04035	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HH204_04045	COG0456	acetyltransferase
HH204_04060	COG1011	Hydrolase
HH204_04075	COG3852	Histidine kinase
HH204_04090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HH204_04110	COG0204	Acyl-transferase
HH204_04120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HH204_04125	COG3084	Protein conserved in bacteria
HH204_04135	COG1763	Mo-molybdopterin cofactor biosynthetic process
HH204_04160	COG2186	Transcriptional regulator
HH204_04165	COG0477	Major facilitator Superfamily
HH204_04170	COG1609	Transcriptional regulator
HH204_04175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_04185	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_04190	COG1129	ABC transporter
HH204_04220	COG1522	sequence-specific DNA binding
HH204_04225	COG0716	FMN binding
HH204_04240	COG3312	ion transport
HH204_04305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HH204_04310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HH204_04315	COG0573	inorganic phosphate transmembrane transporter activity
HH204_04320	COG0581	inorganic phosphate transmembrane transporter activity
HH204_04325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HH204_04330	COG0704	Plays a role in the regulation of phosphate uptake
HH204_04345	COG2382	esterase
HH204_04350	COG0363	glucosamine-6-phosphate deaminase activity
HH204_04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HH204_04365	COG2252	PERMEase
HH204_04370	COG0431	NADPH-dependent FMN reductase
HH204_04375	COG2091	lysine biosynthetic process via aminoadipic acid
HH204_04405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HH204_04435	COG0187	DNA topoisomerase II activity
HH204_04440	COG0561	phosphatase activity
HH204_04455	COG2186	Transcriptional regulator
HH204_04460	COG3734	2-keto-3-deoxy-galactonokinase
HH204_04465	COG0800	Aldolase
HH204_04475	COG2271	Major facilitator Superfamily
HH204_04485	COG5645	(Lipo)protein
HH204_04510	COG2188	Transcriptional regulator
HH204_04525	COG2149	membrane
HH204_04545	COG2610	gluconate transmembrane transporter activity
HH204_04555	COG0583	DNA-binding transcription factor activity
HH204_04560	COG2814	Major facilitator Superfamily
HH204_04590	COG0028	Belongs to the TPP enzyme family
HH204_04595	COG0440	acetolactate synthase activity
HH204_04600	COG2197	response regulator
HH204_04610	COG2271	Major facilitator Superfamily
HH204_04650	COG2188	Transcriptional regulator
HH204_04680	COG1447	Phosphotransferase system cellobiose-specific component IIA
HH204_04685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_04685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_04695	COG1609	Transcriptional regulator
HH204_04710	COG0583	DNA-binding transcription factor activity
HH204_04715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HH204_04720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HH204_04725	COG2828	Protein conserved in bacteria
HH204_04740	COG0697	spore germination
HH204_04745	COG1263	PTS System
HH204_04745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_04755	COG2814	Major facilitator Superfamily
HH204_04765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HH204_04800	COG0583	DNA-binding transcription factor activity
HH204_04825	COG1464	Belongs to the NlpA lipoprotein family
HH204_04840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HH204_04850	COG1064	alcohol dehydrogenase
HH204_04880	COG2211	Major facilitator Superfamily
HH204_04885	COG1501	Belongs to the glycosyl hydrolase 31 family
HH204_04895	COG1486	melibiose metabolic process
HH204_04900	COG1263	PTS System
HH204_04900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_04905	COG2982	Protein involved in outer membrane biogenesis
HH204_04910	COG2233	PERMEase
HH204_04915	COG0786	glutamate:sodium symporter activity
HH204_04935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HH204_04960	COG3152	Membrane
HH204_04970	COG1494	fructose-1,6-bisphosphatase
HH204_04975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HH204_04980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HH204_04985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HH204_05005	COG2860	membrane
HH204_05015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HH204_05015	COG2169	Transcriptional regulator
HH204_05020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HH204_05030	COG1561	YicC-like family, N-terminal region
HH204_05055	COG1131	(ABC) transporter
HH204_05060	COG0842	Transport permease protein
HH204_05090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HH204_05125	COG1519	Transferase
HH204_05130	COG1216	Glycosyl transferase, family 2
HH204_05135	COG0438	transferase activity, transferring glycosyl groups
HH204_05145	COG0859	PFAM glycosyl transferase family 9
HH204_05155	COG1442	glycosyl transferase family 8
HH204_05155	COG1216	Glycosyl transferase, family 2
HH204_05160	COG3307	-O-antigen
HH204_05170	COG0859	PFAM glycosyl transferase family 9
HH204_05185	COG0156	8-amino-7-oxononanoate synthase activity
HH204_05195	COG0463	Glycosyl transferase, family 2
HH204_05200	COG2861	carbohydrate metabolic process
HH204_05205	COG4942	peptidase
HH204_05215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HH204_05220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HH204_05240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HH204_05250	COG2186	Transcriptional regulator
HH204_05270	COG3722	fumarate hydratase activity
HH204_05290	COG0625	glutathione transferase activity
HH204_05305	COG1414	Transcriptional regulator
HH204_05310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HH204_05315	COG3977	Valine--pyruvate aminotransferase
HH204_05320	COG0366	Alpha amylase catalytic
HH204_05325	COG2992	FlgJ-related protein
HH204_05330	COG2207	Transcriptional regulator
HH204_05330	COG1609	Transcriptional regulator
HH204_05335	COG4214	carbohydrate transport
HH204_05345	COG4213	ABC transporter substrate-binding protein
HH204_05360	COG4682	membrane
HH204_05365	COG4682	membrane
HH204_05370	COG3274	enterobacterial common antigen metabolic process
HH204_05400	COG1278	Cold shock
HH204_05405	COG2944	sequence-specific DNA binding
HH204_05410	COG2814	Major facilitator Superfamily
HH204_05430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_05440	COG1609	Transcriptional regulator
HH204_05450	COG2885	chlorophyll binding
HH204_05455	COG0243	molybdopterin cofactor binding
HH204_05460	COG0456	acetyltransferase
HH204_05465	COG2818	Glycosylase
HH204_05470	COG5571	outer membrane autotransporter
HH204_05475	COG2223	nitrite transmembrane transporter activity
HH204_05505	COG0747	negative chemotaxis
HH204_05510	COG0601	transmembrane transport
HH204_05515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HH204_05520	COG0444	Belongs to the ABC transporter superfamily
HH204_05525	COG4608	Belongs to the ABC transporter superfamily
HH204_05540	COG0489	protein tyrosine kinase activity
HH204_05570	COG2194	sulfuric ester hydrolase activity
HH204_05600	COG1215	transferase activity, transferring glycosyl groups
HH204_05605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HH204_05610	COG0457	Tetratricopeptide repeat
HH204_05610	COG3118	belongs to the thioredoxin family
HH204_05615	COG2199	diguanylate cyclase activity
HH204_05615	COG2200	EAL domain
HH204_05625	COG0612	Peptidase, M16
HH204_05645	COG0477	Major facilitator Superfamily
HH204_05650	COG1295	ribonuclease BN
HH204_05655	COG0583	DNA-binding transcription factor activity
HH204_05660	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_05665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HH204_05675	COG1454	alcohol dehydrogenase
HH204_05685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HH204_05690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HH204_05695	COG0671	phosphoesterase, PA-phosphatase related
HH204_05715	COG0589	response to stress
HH204_05725	COG0306	phosphate transporter
HH204_05730	COG2081	HI0933 family
HH204_05735	COG2239	Acts as a magnesium transporter
HH204_05750	COG1124	(ABC) transporter
HH204_05760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HH204_05765	COG0601	transmembrane transport
HH204_05770	COG0747	negative chemotaxis
HH204_05780	COG3479	Phenolic acid decarboxylase
HH204_05820	COG0628	permease
HH204_05835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HH204_05850	COG3714	YhhN family
HH204_05860	COG3776	membrane
HH204_05865	COG0742	ribosomal rna small subunit methyltransferase
HH204_05870	COG0552	protein localization to endoplasmic reticulum
HH204_05875	COG2884	Cell division ATP-binding protein ftsE
HH204_05880	COG2177	Part of the ABC transporter FtsEX involved in
HH204_05895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HH204_05905	COG0683	leucine binding
HH204_05915	COG0683	leucine binding
HH204_05920	COG0559	Belongs to the binding-protein-dependent transport system permease family
HH204_05970	COG0584	glycerophosphoryl diester phosphodiesterase
HH204_05980	COG0405	Gamma-glutamyltransferase
HH204_05985	COG1247	-acetyltransferase
HH204_05995	COG0673	inositol 2-dehydrogenase activity
HH204_06000	COG1741	Belongs to the pirin family
HH204_06005	COG1609	Transcriptional regulator
HH204_06010	COG3265	gluconokinase activity
HH204_06015	COG2610	gluconate transmembrane transporter activity
HH204_06025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HH204_06050	COG0058	SHG alpha-glucan phosphorylase activity
HH204_06055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HH204_06070	COG1349	DNA-binding transcription factor activity
HH204_06080	COG0058	SHG alpha-glucan phosphorylase activity
HH204_06085	COG1640	4-alpha-glucanotransferase
HH204_06090	COG2610	gluconate transmembrane transporter activity
HH204_06100	COG1040	competence protein
HH204_06125	COG1918	ferrous iron import across plasma membrane
HH204_06130	COG2183	response to ionizing radiation
HH204_06135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HH204_06140	COG0745	RESPONSE REGULATOR receiver
HH204_06160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HH204_06165	COG1011	Hydrolase
HH204_06175	COG0494	nUDIX hydrolase
HH204_06180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HH204_06205	COG4796	Type ii and iii secretion system protein
HH204_06220	COG3266	domain, Protein
HH204_06225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HH204_06230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HH204_06255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HH204_06265	COG0402	S-adenosylhomocysteine deaminase activity
HH204_06270	COG0738	Major facilitator superfamily
HH204_06295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HH204_06300	COG1289	transmembrane transporter activity
HH204_06310	COG1765	OsmC-like protein
HH204_06315	COG3954	Phosphoribulokinase
HH204_06325	COG0429	hydrolase of the alpha beta-hydrolase fold
HH204_06335	COG0488	(ABC) transporter
HH204_06350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HH204_06355	COG1047	Peptidyl-prolyl cis-trans
HH204_06365	COG0545	Peptidyl-prolyl cis-trans isomerase
HH204_06370	COG2964	Protein conserved in bacteria
HH204_06425	COG0051	transcription antitermination factor activity, RNA binding
HH204_06450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HH204_06465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HH204_06530	COG0201	protein transport
HH204_06555	COG0202	RNA polymerase activity
HH204_06570	COG0789	Transcriptional regulator
HH204_06575	COG3036	rescue of stalled ribosome
HH204_06605	COG0758	DNA mediated transformation
HH204_06615	COG0551	DNA topoisomerase type I activity
HH204_06635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HH204_06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_06680	COG1309	transcriptional regulator
HH204_06705	COG3924	membrane
HH204_06710	COG0439	Biotin carboxylase
HH204_06715	COG0511	ligase activity, forming carbon-carbon bonds
HH204_06740	COG2199	diguanylate cyclase activity
HH204_06740	COG2200	EAL domain
HH204_06745	COG1077	Cell shape determining protein MreB Mrl
HH204_06750	COG1792	Involved in formation and maintenance of cell shape
HH204_06755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HH204_06765	COG1530	ribonuclease E activity
HH204_06770	COG3164	Protein of unknown function
HH204_06775	COG0312	modulator of DNA gyrase
HH204_06780	COG0583	DNA-binding transcription factor activity
HH204_06795	COG1289	transmembrane transporter activity
HH204_06800	COG2732	(Barnase) inhibitor
HH204_06825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HH204_06830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HH204_06835	COG3105	Protein conserved in bacteria
HH204_06840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HH204_06860	COG0625	glutathione transferase activity
HH204_06865	COG2969	positive regulation of protein catabolic process
HH204_06875	COG0493	'glutamate synthase
HH204_06885	COG1242	4 iron, 4 sulfur cluster binding
HH204_06890	COG2271	Major facilitator Superfamily
HH204_06905	COG1312	Catalyzes the dehydration of D-mannonate
HH204_06910	COG5002	protein histidine kinase activity
HH204_06910	COG2198	Histidine kinase
HH204_06910	COG0784	Response regulator, receiver
HH204_06915	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HH204_06920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HH204_06925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_06935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_06940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HH204_06945	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HH204_06950	COG1137	ATPase activity
HH204_06955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HH204_06960	COG3117	lipopolysaccharide transmembrane transporter activity
HH204_06965	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HH204_06975	COG0530	calcium, potassium:sodium antiporter activity
HH204_06980	COG1127	ABC transporter
HH204_06985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HH204_06990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HH204_06995	COG2854	intermembrane phospholipid transfer
HH204_07000	COG3113	response to antibiotic
HH204_07005	COG5007	Belongs to the BolA IbaG family
HH204_07015	COG3423	Transcriptional regulator
HH204_07020	COG0142	geranyltranstransferase activity
HH204_07035	COG0697	spore germination
HH204_07045	COG2027	D-alanyl-D-alanine carboxypeptidase
HH204_07055	COG1534	Rna-binding protein
HH204_07065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HH204_07070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HH204_07080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HH204_07125	COG0195	Participates in both transcription termination and antitermination
HH204_07170	COG0814	amino acid
HH204_07175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_07180	COG0826	peptidase U32
HH204_07185	COG0826	peptidase U32
HH204_07190	COG3154	lipid carrier protein
HH204_07195	COG3153	acetyltransferase
HH204_07210	COG0693	protein deglycase activity
HH204_07215	COG0702	epimerase
HH204_07220	COG0701	Predicted permease
HH204_07225	COG2823	Periplasmic or secreted lipoprotein
HH204_07245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HH204_07260	COG1063	alcohol dehydrogenase
HH204_07265	COG3775	system Galactitol-specific IIC component
HH204_07270	COG3414	Phosphotransferase system galactitol-specific IIB component
HH204_07275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_07285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_07285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_07290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_07290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_07290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_07295	COG1105	Belongs to the carbohydrate kinase PfkB family
HH204_07310	COG1349	DNA-binding transcription factor activity
HH204_07315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_07320	COG2721	sulfolactate sulfo-lyase activity
HH204_07330	COG2271	Major facilitator Superfamily
HH204_07340	COG2084	Dehydrogenase
HH204_07345	COG1929	Belongs to the glycerate kinase type-1 family
HH204_07375	COG1741	Belongs to the pirin family
HH204_07380	COG0583	DNA-binding transcription factor activity
HH204_07385	COG3152	Membrane
HH204_07390	COG0435	Glutathione S-transferase
HH204_07395	COG2259	Doxx family
HH204_07405	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HH204_07410	COG4575	ribosome binding
HH204_07415	COG1422	Protein of unknown function (DUF1090)
HH204_07425	COG0586	Pfam SNARE associated Golgi protein
HH204_07430	COG2186	Transcriptional regulator
HH204_07435	COG2271	Major facilitator Superfamily
HH204_07445	COG2721	sulfolactate sulfo-lyase activity
HH204_07460	COG0861	Integral membrane protein TerC family
HH204_07465	COG0673	inositol 2-dehydrogenase activity
HH204_07470	COG1451	nucleotide metabolic process
HH204_07490	COG0446	pyridine nucleotide-disulphide oxidoreductase
HH204_07490	COG1902	pentaerythritol trinitrate reductase activity
HH204_07535	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HH204_07535	COG3408	Glycogen debranching enzyme
HH204_07545	COG0531	amino acid
HH204_07550	COG0531	amino acid
HH204_07555	COG2731	YhcH YjgK YiaL family protein
HH204_07560	COG3250	beta-galactosidase activity
HH204_07565	COG1609	Transcriptional regulator
HH204_07570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HH204_07580	COG1695	Transcriptional regulator
HH204_07590	COG2375	cellular response to nickel ion
HH204_07605	COG1461	Dihydroxyacetone kinase
HH204_07610	COG2376	Dihydroxyacetone kinase
HH204_07680	COG3247	response to pH
HH204_07690	COG0784	Response regulator, receiver
HH204_07690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_07690	COG2198	Histidine kinase
HH204_07690	COG2205	protein histidine kinase activity
HH204_07695	COG2197	response regulator
HH204_07720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HH204_07725	COG0358	DNA primase activity
HH204_07730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HH204_07810	COG4991	sh3 domain protein
HH204_07815	COG3025	triphosphatase activity
HH204_07840	COG2960	long-chain fatty acid transporting porin activity
HH204_07855	COG3384	dioxygenase
HH204_07860	COG0754	glutathionylspermidine amidase activity
HH204_07875	COG0494	nUDIX hydrolase
HH204_07880	COG3151	Protein conserved in bacteria
HH204_07885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HH204_07890	COG3150	esterase
HH204_07900	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HH204_07905	COG2249	NAD(P)H dehydrogenase (quinone) activity
HH204_07910	COG0642	Histidine kinase
HH204_07920	COG3111	PFAM Bacterial OB fold (BOF) protein
HH204_07925	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HH204_07930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HH204_07935	COG0204	Acyl-transferase
HH204_07940	COG2132	Multicopper oxidase
HH204_07945	COG1032	radical SAM domain protein
HH204_07955	COG0656	L-ascorbic acid biosynthetic process
HH204_07960	COG1979	alcohol dehydrogenase
HH204_07965	COG2207	Transcriptional regulator
HH204_07970	COG0586	Pfam SNARE associated Golgi protein
HH204_07975	COG0626	cystathionine gamma-synthase activity
HH204_07985	COG0848	biopolymer transport protein
HH204_07990	COG2211	Major facilitator Superfamily
HH204_08015	COG0625	glutathione transferase activity
HH204_08030	COG0754	glutathionylspermidine amidase activity
HH204_08035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HH204_08060	COG0626	cystathionine gamma-synthase activity
HH204_08095	COG1811	Na channel or pump
HH204_08100	COG1982	Orn Lys Arg decarboxylase major
HH204_08105	COG2211	Major facilitator Superfamily
HH204_08120	COG1194	a g-specific adenine glycosylase
HH204_08130	COG3171	Protein conserved in bacteria
HH204_08140	COG4214	carbohydrate transport
HH204_08155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HH204_08170	COG0762	integral membrane protein
HH204_08175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HH204_08180	COG2805	Type II/IV secretion system protein
HH204_08205	COG0189	ligase activity
HH204_08210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HH204_08215	COG2356	endonuclease I
HH204_08225	COG2814	Major facilitator Superfamily
HH204_08260	COG2146	nitrite reductase [NAD(P)H] activity
HH204_08275	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_08280	COG1414	Transcriptional regulator
HH204_08310	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_08315	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HH204_08335	COG0501	Belongs to the peptidase M48B family
HH204_08340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HH204_08355	COG0191	fructose-bisphosphate aldolase activity
HH204_08360	COG0668	transmembrane transport
HH204_08370	COG2968	Membrane
HH204_08390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HH204_08395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HH204_08415	COG0006	proline dipeptidase activity
HH204_08420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HH204_08425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HH204_08445	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_08450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HH204_08470	COG2723	6-phospho-beta-galactosidase activity
HH204_08475	COG1737	Transcriptional regulator
HH204_08485	COG1272	protein, Hemolysin III
HH204_08495	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HH204_08505	COG0716	FMN binding
HH204_08510	COG4974	Belongs to the 'phage' integrase family
HH204_08520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HH204_08545	COG4942	peptidase
HH204_08555	COG4974	Belongs to the 'phage' integrase family
HH204_08580	COG2814	Major facilitator Superfamily
HH204_08595	COG0667	Aldo Keto reductase
HH204_08600	COG2249	NAD(P)H dehydrogenase (quinone) activity
HH204_08635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HH204_08640	COG1393	Belongs to the ArsC family
HH204_08645	COG3104	oligopeptide transport
HH204_08655	COG1538	Outer membrane efflux protein
HH204_08660	COG1289	transmembrane transporter activity
HH204_08675	COG3592	Divergent 4Fe-4S mono-cluster
HH204_08680	COG2388	GCN5-related N-acetyl-transferase
HH204_08690	COG3539	Fimbrial protein
HH204_08695	COG3539	Fimbrial protein
HH204_08700	COG3539	Fimbrial protein
HH204_08705	COG3188	usher protein
HH204_08710	COG3121	Chaperone
HH204_08715	COG3539	Fimbrial protein
HH204_08730	COG4974	Belongs to the 'phage' integrase family
HH204_08735	COG0582	viral genome integration into host DNA
HH204_08740	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HH204_08745	COG1846	Transcriptional regulator
HH204_08750	COG0697	spore germination
HH204_08800	COG0667	Aldo Keto reductase
HH204_08805	COG0814	amino acid
HH204_08820	COG0183	Belongs to the thiolase family
HH204_08830	COG0823	Involved in the tonB-independent uptake of proteins
HH204_08845	COG2814	Major facilitator Superfamily
HH204_08880	COG3842	ATPase activity
HH204_08885	COG0395	ABC-type sugar transport system, permease component
HH204_08890	COG1175	transmembrane transport
HH204_08895	COG1917	Cupin 2, conserved barrel domain protein
HH204_08900	COG1794	racemase activity, acting on amino acids and derivatives
HH204_08915	COG1609	Transcriptional regulator
HH204_08920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_08925	COG2723	6-phospho-beta-galactosidase activity
HH204_08930	COG2186	Transcriptional regulator
HH204_08940	COG1609	Transcriptional regulator
HH204_08955	COG0667	Aldo Keto reductase
HH204_08965	COG0861	Integral membrane protein TerC family
HH204_09000	COG2165	general secretion pathway protein
HH204_09005	COG4795	General secretion pathway protein
HH204_09015	COG4967	type IV pilus modification protein PilV
HH204_09020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HH204_09025	COG1025	Belongs to the peptidase M16 family
HH204_09035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HH204_09045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HH204_09045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HH204_09050	COG0860	N-Acetylmuramoyl-L-alanine amidase
HH204_09055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HH204_09085	COG4656	Part of a membrane complex involved in electron transport
HH204_09090	COG1454	alcohol dehydrogenase
HH204_09090	COG1012	belongs to the aldehyde dehydrogenase family
HH204_09285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HH204_09290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HH204_09295	COG2166	iron-sulfur cluster assembly
HH204_09300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HH204_09310	COG0583	DNA-binding transcription factor activity
HH204_09315	COG2363	Small membrane protein
HH204_09325	COG1349	DNA-binding transcription factor activity
HH204_09345	COG0738	Major facilitator superfamily
HH204_09355	COG0235	Class ii aldolase
HH204_09360	COG1454	alcohol dehydrogenase
HH204_09380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_09395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HH204_09400	COG2011	ABC-type metal ion transport system permease component
HH204_09405	COG1464	Belongs to the NlpA lipoprotein family
HH204_09410	COG0477	Major facilitator Superfamily
HH204_09420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HH204_09425	COG1760	l-serine dehydratase
HH204_09430	COG0814	amino acid
HH204_09435	COG1611	Belongs to the LOG family
HH204_09450	COG3098	single-species biofilm formation
HH204_09455	COG0564	pseudouridine synthase activity
HH204_09460	COG0716	FMN binding
HH204_09465	COG2271	Major facilitator Superfamily
HH204_09470	COG4948	Mandelate Racemase Muconate Lactonizing
HH204_09475	COG4948	Mandelate Racemase Muconate Lactonizing
HH204_09480	COG1929	Belongs to the glycerate kinase type-1 family
HH204_09485	COG3437	response regulator, receiver
HH204_09485	COG4999	Histidine kinase
HH204_09485	COG3850	Histidine kinase
HH204_09485	COG2205	protein histidine kinase activity
HH204_09495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HH204_09500	COG3956	TIGRFAM MazG family protein
HH204_09525	COG0602	queuosine metabolic process
HH204_09530	COG0720	synthase
HH204_09550	COG2234	aminopeptidase activity
HH204_09610	COG1388	LysM domain
HH204_09610	COG4942	peptidase
HH204_09615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HH204_09640	COG0163	prenyltransferase activity
HH204_09645	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HH204_09725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_09730	COG4558	Periplasmic binding protein
HH204_09735	COG3720	iron ion transport
HH204_09755	COG0679	Auxin Efflux Carrier
HH204_09770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HH204_09775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HH204_09780	COG1121	(ABC) transporter
HH204_09790	COG1609	Transcriptional regulator
HH204_09795	COG1940	carbohydrate kinase activity
HH204_09800	COG1447	Phosphotransferase system cellobiose-specific component IIA
HH204_09810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_09815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_09830	COG2723	6-phospho-beta-galactosidase activity
HH204_09840	COG0309	Hydrogenase expression formation protein (HypE)
HH204_09845	COG0409	Hydrogenase expression formation protein
HH204_09850	COG0298	carbon dioxide binding
HH204_09855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HH204_09870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HH204_09875	COG0651	ATP synthesis coupled electron transport
HH204_09880	COG0650	Formate hydrogenlyase subunit 4
HH204_09885	COG3261	NADH dehydrogenase
HH204_09885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HH204_09890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HH204_09895	COG3260	NADH ubiquinone oxidoreductase 20
HH204_09905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HH204_09915	COG2723	6-phospho-beta-galactosidase activity
HH204_09920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_09920	COG1263	PTS System
HH204_09930	COG1609	Transcriptional regulator
HH204_09935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HH204_09940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HH204_09945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HH204_09975	COG1349	DNA-binding transcription factor activity
HH204_09980	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_09985	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_09995	COG3732	PTS system glucitol sorbitol-specific
HH204_10000	COG3730	PTS system glucitol sorbitol-specific
HH204_10005	COG2951	lytic endotransglycosylase activity
HH204_10010	COG1121	(ABC) transporter
HH204_10015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HH204_10020	COG0803	Belongs to the bacterial solute-binding protein 9 family
HH204_10025	COG1546	Belongs to the CinA family
HH204_10045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HH204_10080	COG2823	Periplasmic or secreted lipoprotein
HH204_10085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HH204_10090	COG1238	metal cluster binding
HH204_10110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HH204_10115	COG2814	Major facilitator Superfamily
HH204_10120	COG1566	PFAM secretion protein HlyD family protein
HH204_10130	COG1846	Transcriptional regulator
HH204_10145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HH204_10155	COG4176	ABC-type proline glycine betaine transport system permease component
HH204_10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HH204_10180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HH204_10185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_10190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HH204_10195	COG4575	ribosome binding
HH204_10215	COG2916	Histone family protein nucleoid-structuring protein H-NS
HH204_10230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HH204_10235	COG0640	Transcriptional regulator
HH204_10245	COG0583	DNA-binding transcription factor activity
HH204_10250	COG3284	Transcriptional regulator
HH204_10255	COG1012	belongs to the aldehyde dehydrogenase family
HH204_10260	COG3539	Fimbrial protein
HH204_10265	COG3121	Chaperone
HH204_10285	COG3188	usher protein
HH204_10295	COG3539	Fimbrial protein
HH204_10300	COG2197	response regulator
HH204_10315	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_10325	COG0235	Class ii aldolase
HH204_10330	COG1126	abc transporter atp-binding protein
HH204_10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_10370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_10375	COG2207	Transcriptional regulator
HH204_10375	COG3708	Transcriptional regulator
HH204_10405	COG2867	negative regulation of translational initiation
HH204_10425	COG0497	DNA recombination
HH204_10440	COG4536	flavin adenine dinucleotide binding
HH204_10445	COG4137	Cytochrome C assembly protein
HH204_10450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HH204_10490	COG2885	chlorophyll binding
HH204_10495	COG2199	diguanylate cyclase activity
HH204_10505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HH204_10510	COG1605	Chorismate mutase
HH204_10510	COG0287	Prephenate dehydrogenase
HH204_10520	COG0077	Prephenate dehydratase
HH204_10520	COG1605	Chorismate mutase
HH204_10530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HH204_10535	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HH204_10550	COG0542	response to heat
HH204_10575	COG0477	Major facilitator Superfamily
HH204_10580	COG5544	Lipoprotein
HH204_10585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HH204_10600	COG3118	belongs to the thioredoxin family
HH204_10605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HH204_10620	COG0513	Belongs to the DEAD box helicase family
HH204_10630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HH204_10645	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HH204_10650	COG3026	antisigma factor binding
HH204_10655	COG3086	response to oxidative stress
HH204_10665	COG0681	Belongs to the peptidase S26 family
HH204_10685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HH204_10695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HH204_10700	COG1737	Transcriptional regulator
HH204_10705	COG0560	Phosphoserine phosphatase
HH204_10720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HH204_10720	COG0047	phosphoribosylformylglycinamidine synthase activity
HH204_10725	COG2205	protein histidine kinase activity
HH204_10735	COG2204	response regulator
HH204_10740	COG0347	Belongs to the P(II) protein family
HH204_10745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HH204_10745	COG1017	nitric oxide dioxygenase activity
HH204_10755	COG2259	Doxx family
HH204_10760	COG1940	carbohydrate kinase activity
HH204_10765	COG0457	Tetratricopeptide repeat
HH204_10770	COG2814	Major facilitator Superfamily
HH204_10770	COG0477	Major facilitator Superfamily
HH204_10775	COG2017	converts alpha-aldose to the beta-anomer
HH204_10780	COG2814	Major facilitator Superfamily
HH204_10785	COG3711	transcriptional antiterminator
HH204_10790	COG3683	transport system, periplasmic component
HH204_10795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HH204_10825	COG0822	iron-sulfur transferase activity
HH204_10845	COG0633	Ferredoxin
HH204_10850	COG2975	iron-sulfur cluster assembly
HH204_10870	COG2897	thiosulfate sulfurtransferase activity
HH204_10875	COG2373	Large extracellular alpha-helical protein
HH204_10880	COG4953	penicillin-binding protein 1C
HH204_10910	COG2976	Protein conserved in bacteria
HH204_10930	COG1645	bacterial-type flagellum-dependent swarming motility
HH204_10940	COG0517	IMP dehydrogenase activity
HH204_10940	COG0516	GMP reductase activity
HH204_10950	COG3119	arylsulfatase activity
HH204_10955	COG0641	radical SAM
HH204_10975	COG2200	EAL domain
HH204_10990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HH204_11005	COG2723	6-phospho-beta-galactosidase activity
HH204_11015	COG2233	PERMEase
HH204_11030	COG1393	Belongs to the ArsC family
HH204_11035	COG4783	chaperone-mediated protein folding
HH204_11045	COG0628	permease
HH204_11050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HH204_11055	COG2716	regulation of RNA biosynthetic process
HH204_11065	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HH204_11075	COG2321	neutral zinc metallopeptidase
HH204_11080	COG1444	tRNA N-acetyltransferase activity
HH204_11085	COG0400	carboxylic ester hydrolase activity
HH204_11100	COG1393	Belongs to the ArsC family
HH204_11110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HH204_11115	COG0493	'glutamate synthase
HH204_11115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HH204_11125	COG5342	invasion associated locus B
HH204_11130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HH204_11135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HH204_11145	COG4810	utilization protein
HH204_11235	COG0860	N-Acetylmuramoyl-L-alanine amidase
HH204_11255	COG2837	iron assimilation
HH204_11265	COG4150	thiosulfate binding
HH204_11270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HH204_11275	COG4208	sulfate ABC transporter
HH204_11290	COG4319	ketosteroid isomerase
HH204_11330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HH204_11350	COG3530	Putative quorum-sensing-regulated virulence factor
HH204_11355	COG0385	Bile acid
HH204_11360	COG0583	DNA-binding transcription factor activity
HH204_11390	COG3415	Transposase
HH204_11395	COG3415	Transposase
HH204_11410	COG2199	diguanylate cyclase activity
HH204_11410	COG2200	EAL domain
HH204_11415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HH204_11430	COG0667	Aldo Keto reductase
HH204_11435	COG3961	Belongs to the TPP enzyme family
HH204_11450	COG3279	Response regulator of the LytR AlgR family
HH204_11455	COG3275	phosphorelay sensor kinase activity
HH204_11470	COG0436	Aminotransferase
HH204_11480	COG2807	transmembrane transport
HH204_11485	COG0590	tRNA wobble adenosine to inosine editing
HH204_11490	COG0583	DNA-binding transcription factor activity
HH204_11510	COG2116	formate transmembrane transporter activity
HH204_11515	COG2853	Lipoprotein
HH204_11525	COG3691	Protein conserved in bacteria
HH204_11540	COG2062	phosphohistidine phosphatase, SixA
HH204_11565	COG0730	response to heat
HH204_11570	COG3101	peptidyl-lysine hydroxylation
HH204_11585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HH204_11605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HH204_11615	COG0586	Pfam SNARE associated Golgi protein
HH204_11625	COG0285	dihydrofolate synthase activity
HH204_11630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HH204_11635	COG1286	toxin biosynthetic process
HH204_11640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HH204_11645	COG0163	prenyltransferase activity
HH204_11670	COG4160	amino acid transport
HH204_11675	COG4598	ABC transporter
HH204_11690	COG1090	epimerase
HH204_11695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HH204_11700	COG0625	glutathione transferase activity
HH204_11705	COG0625	glutathione transferase activity
HH204_11710	COG0622	Phosphoesterase
HH204_11715	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HH204_11720	COG0280	phosphate acetyltransferase
HH204_11720	COG0857	belongs to the CobB CobQ family
HH204_11740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HH204_11745	COG0490	domain, Protein
HH204_11745	COG0471	metal ion transport
HH204_11755	COG0436	Aminotransferase
HH204_11760	COG0583	DNA-binding transcription factor activity
HH204_11810	COG0839	Belongs to the complex I subunit 6 family
HH204_11820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HH204_11825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HH204_11840	COG2153	protein acetylation
HH204_11845	COG1169	isochorismate synthase
HH204_11870	COG0318	PFAM AMP-dependent synthetase and ligase
HH204_11880	COG5464	transposase or invertase
HH204_11900	COG1414	Transcriptional regulator
HH204_11910	COG2271	Major facilitator Superfamily
HH204_11920	COG0247	lactate metabolic process
HH204_11930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HH204_11935	COG2271	Major facilitator Superfamily
HH204_11940	COG0584	glycerophosphoryl diester phosphodiesterase
HH204_11945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HH204_11970	COG2205	protein histidine kinase activity
HH204_11970	COG0784	Response regulator, receiver
HH204_11980	COG0642	Histidine kinase
HH204_11980	COG2198	Histidine kinase
HH204_11995	COG2169	Transcriptional regulator
HH204_11995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HH204_12000	COG3145	DNA-N1-methyladenine dioxygenase activity
HH204_12005	COG4615	Cyclic peptide transporter
HH204_12010	COG2239	Acts as a magnesium transporter
HH204_12015	COG0659	secondary active sulfate transmembrane transporter activity
HH204_12030	COG0628	permease
HH204_12070	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HH204_12075	COG5532	Uncharacterized conserved protein (DUF2303)
HH204_12115	COG4626	Terminase
HH204_12115	COG1802	Transcriptional regulator
HH204_12135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HH204_12150	COG1403	HNH endonuclease
HH204_12155	COG0484	heat shock protein binding
HH204_12180	COG3179	chitinase
HH204_12230	COG1802	Transcriptional regulator
HH204_12230	COG4626	Terminase
HH204_12235	COG4695	Portal protein
HH204_12325	COG3706	GGDEF domain
HH204_12330	COG3300	MHYT domain
HH204_12330	COG5001	Diguanylate cyclase
HH204_12355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HH204_12400	COG1349	DNA-binding transcription factor activity
HH204_12405	COG0494	nUDIX hydrolase
HH204_12425	COG1061	Type III restriction enzyme res subunit
HH204_12430	COG1187	pseudouridine synthase activity
HH204_12435	COG2814	Major facilitator Superfamily
HH204_12445	COG4172	Belongs to the ABC transporter superfamily
HH204_12450	COG4239	(ABC) transporter, permease
HH204_12455	COG4174	ABC transporter (Permease)
HH204_12460	COG4166	transmembrane transport
HH204_12465	COG2200	EAL domain
HH204_12470	COG0791	NLP P60 protein
HH204_12475	COG0671	phosphoesterase, PA-phosphatase related
HH204_12480	COG0523	cobalamin synthesis protein
HH204_12485	COG0246	Mannitol dehydrogenase
HH204_12490	COG1312	Catalyzes the dehydration of D-mannonate
HH204_12510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_12510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_12515	COG1105	Belongs to the carbohydrate kinase PfkB family
HH204_12530	COG2855	membrane
HH204_12535	COG0583	DNA-binding transcription factor activity
HH204_12540	COG0833	amino acid
HH204_12550	COG4771	TonB-dependent receptor
HH204_12565	COG2311	Membrane
HH204_12580	COG1129	ABC transporter
HH204_12590	COG2949	membrane
HH204_12600	COG1346	cytolysis
HH204_12610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HH204_12615	COG3659	wide pore channel activity
HH204_12630	COG2723	6-phospho-beta-galactosidase activity
HH204_12635	COG1538	Outer membrane efflux protein
HH204_12640	COG0586	Pfam SNARE associated Golgi protein
HH204_12650	COG1686	Belongs to the peptidase S11 family
HH204_12665	COG1472	Belongs to the glycosyl hydrolase 3 family
HH204_12670	COG1732	Glycine betaine
HH204_12675	COG1174	glycine betaine transport
HH204_12680	COG1125	glycine betaine transport
HH204_12685	COG1174	glycine betaine transport
HH204_12695	COG3275	phosphorelay sensor kinase activity
HH204_12705	COG4807	Protein conserved in bacteria
HH204_12725	COG5455	response to cobalt ion
HH204_12735	COG2252	PERMEase
HH204_12745	COG0583	DNA-binding transcription factor activity
HH204_12760	COG0351	phosphomethylpyrimidine kinase
HH204_12765	COG1830	Aldolase
HH204_12775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HH204_12800	COG1070	Carbohydrate kinase
HH204_12810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HH204_12815	COG4948	Mandelate Racemase Muconate Lactonizing
HH204_12820	COG0747	negative chemotaxis
HH204_12825	COG0601	transmembrane transport
HH204_12835	COG0444	Belongs to the ABC transporter superfamily
HH204_12840	COG4608	Belongs to the ABC transporter superfamily
HH204_12855	COG0745	RESPONSE REGULATOR receiver
HH204_12885	COG1301	dicarboxylic acid transport
HH204_12905	COG5002	protein histidine kinase activity
HH204_12910	COG0443	Heat shock 70 kDa protein
HH204_12915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HH204_12930	COG2982	Protein involved in outer membrane biogenesis
HH204_12935	COG1253	flavin adenine dinucleotide binding
HH204_13000	COG0463	Glycosyl transferase, family 2
HH204_13005	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HH204_13010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HH204_13015	COG1051	belongs to the nudix hydrolase family
HH204_13020	COG0297	glycogen (starch) synthase activity
HH204_13095	COG0438	transferase activity, transferring glycosyl groups
HH204_13100	COG1215	transferase activity, transferring glycosyl groups
HH204_13120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HH204_13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HH204_13155	COG0583	DNA-binding transcription factor activity
HH204_13165	COG0531	amino acid
HH204_13170	COG0640	Transcriptional regulator
HH204_13175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HH204_13180	COG2925	Exonuclease
HH204_13195	COG1289	transmembrane transporter activity
HH204_13215	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HH204_13225	COG1942	4-Oxalocrotonate Tautomerase
HH204_13230	COG0583	DNA-binding transcription factor activity
HH204_13240	COG0477	Major facilitator Superfamily
HH204_13250	COG5001	Diguanylate cyclase
HH204_13250	COG3300	MHYT domain
HH204_13255	COG3615	Tellurite resistance protein tehB
HH204_13280	COG3706	GGDEF domain
HH204_13455	COG4771	TonB-dependent receptor
HH204_13460	COG1021	2,3-dihydroxybenzoate-AMP ligase
HH204_13480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HH204_13480	COG3433	isochorismatase activity
HH204_13480	COG2226	methyltransferase
HH204_13495	COG1132	(ABC) transporter
HH204_13500	COG2814	Major facilitator Superfamily
HH204_13505	COG1169	isochorismate synthase
HH204_13510	COG0582	viral genome integration into host DNA
HH204_13525	COG0534	Mate efflux family protein
HH204_13535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HH204_13555	COG0604	alcohol dehydrogenase
HH204_13560	COG1309	transcriptional regulator
HH204_13565	COG0025	NhaP-type Na H and K H
HH204_13585	COG2801	Transposase and inactivated derivatives
HH204_13665	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
HH204_13735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_13740	COG0583	DNA-binding transcription factor activity
HH204_13745	COG1486	melibiose metabolic process
HH204_13750	COG3118	belongs to the thioredoxin family
HH204_13755	COG2207	Transcriptional regulator
HH204_13760	COG1881	PFAM PEBP family protein
HH204_13765	COG1902	pentaerythritol trinitrate reductase activity
HH204_13775	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_13795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HH204_13800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HH204_13805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HH204_13825	COG3414	Phosphotransferase system galactitol-specific IIB component
HH204_13830	COG3775	system Galactitol-specific IIC component
HH204_13835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HH204_13845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HH204_13855	COG1129	ABC transporter
HH204_13860	COG1879	ABC-type sugar transport system periplasmic component
HH204_13865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_13870	COG1070	Carbohydrate kinase
HH204_13875	COG0582	viral genome integration into host DNA
HH204_13920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HH204_13935	COG1418	mRNA catabolic process
HH204_13940	COG0270	DNA (cytosine-5-)-methyltransferase activity
HH204_13945	COG3727	T/G mismatch-specific endonuclease activity
HH204_13950	COG0697	spore germination
HH204_13955	COG2354	Protein conserved in bacteria
HH204_13985	COG0366	Alpha amylase catalytic
HH204_14010	COG2197	response regulator
HH204_14020	COG2197	response regulator
HH204_14055	COG3318	Belongs to the UPF0149 family
HH204_14055	COG3012	SEC-C Motif Domain Protein
HH204_14070	COG1528	Iron-storage protein
HH204_14085	COG0477	Major facilitator Superfamily
HH204_14095	COG2211	Major facilitator Superfamily
HH204_14105	COG1528	Iron-storage protein
HH204_14120	COG1879	ABC-type sugar transport system periplasmic component
HH204_14130	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_14155	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HH204_14165	COG3102	Protein conserved in bacteria
HH204_14185	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HH204_14190	COG1801	Protein of unknown function DUF72
HH204_14195	COG1335	isochorismatase
HH204_14205	COG0494	nUDIX hydrolase
HH204_14230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HH204_14240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HH204_14245	COG0739	heme binding
HH204_14250	COG1560	Kdo2-lipid A biosynthetic process
HH204_14260	COG1737	Transcriptional regulator
HH204_14270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HH204_14275	COG0129	dihydroxy-acid dehydratase activity
HH204_14290	COG3141	response to X-ray
HH204_14295	COG2979	Protein of unknown function (DUF533)
HH204_14300	COG1770	oligopeptidase
HH204_14305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HH204_14315	COG2372	response to copper ion
HH204_14320	COG1276	copper resistance
HH204_14335	COG2990	Protein conserved in bacteria
HH204_14360	COG3008	intermembrane lipid transfer
HH204_14365	COG2995	paraquat-inducible protein a
HH204_14370	COG1956	GAF domain-containing protein
HH204_14390	COG2814	Major facilitator Superfamily
HH204_14395	COG1414	Transcriptional regulator
HH204_14430	COG0768	penicillin binding
HH204_14435	COG2226	methyltransferase
HH204_14450	COG3716	PTS system mannose fructose sorbose family IID component
HH204_14455	COG3715	PTS system
HH204_14460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_14460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_14465	COG1253	flavin adenine dinucleotide binding
HH204_14470	COG2200	EAL domain
HH204_14480	COG1760	l-serine dehydratase
HH204_14500	COG0251	oxidation-reduction process
HH204_14505	COG1199	ATP-dependent helicase activity
HH204_14515	COG3065	identical protein binding
HH204_14525	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HH204_14535	COG2894	cell division
HH204_14550	COG0179	Fumarylacetoacetate (FAA) hydrolase
HH204_14580	COG2719	SpoVR family
HH204_14605	COG1619	proteins homologs of microcin C7 resistance protein MccF
HH204_14615	COG4774	siderophore transport
HH204_14630	COG2308	Evidence 4 Homologs of previously reported genes of
HH204_14670	COG0583	DNA-binding transcription factor activity
HH204_14675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HH204_14690	COG1882	Formate acetyltransferase
HH204_14725	COG0583	DNA-binding transcription factor activity
HH204_14755	COG0583	DNA-binding transcription factor activity
HH204_14770	COG3122	Protein conserved in bacteria
HH204_14795	COG2885	chlorophyll binding
HH204_14805	COG3501	Rhs element vgr protein
HH204_14895	COG0012	GTP binding
HH204_14915	COG0659	secondary active sulfate transmembrane transporter activity
HH204_14945	COG2890	protein-(glutamine-N5) methyltransferase activity
HH204_14965	COG0387	Pfam Sodium calcium exchanger
HH204_14970	COG4572	Cation transport regulator
HH204_14975	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HH204_14985	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HH204_14990	COG3707	response regulator
HH204_15000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HH204_15010	COG1116	anion transmembrane transporter activity
HH204_15015	COG2146	nitrite reductase [NAD(P)H] activity
HH204_15015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HH204_15025	COG4932	domain protein
HH204_15030	COG2197	response regulator
HH204_15035	COG3850	Histidine kinase
HH204_15040	COG2223	nitrite transmembrane transporter activity
HH204_15050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HH204_15055	COG1140	nitrate reductase beta subunit
HH204_15060	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HH204_15065	COG2181	nitrate reductase activity
HH204_15075	COG1522	sequence-specific DNA binding
HH204_15115	COG0788	formyltetrahydrofolate deformylase activity
HH204_15125	COG1752	Esterase of the alpha-beta hydrolase superfamily
HH204_15130	COG0745	RESPONSE REGULATOR receiver
HH204_15135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HH204_15140	COG2916	Histone family protein nucleoid-structuring protein H-NS
HH204_15150	COG1435	thymidine kinase activity
HH204_15155	COG1454	alcohol dehydrogenase
HH204_15155	COG1012	belongs to the aldehyde dehydrogenase family
HH204_15165	COG2095	MarC family integral membrane protein
HH204_15175	COG4166	transmembrane transport
HH204_15180	COG0601	transmembrane transport
HH204_15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HH204_15190	COG0444	Belongs to the ABC transporter superfamily
HH204_15200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HH204_15225	COG2353	YceI-like domain
HH204_15235	COG2350	Protein conserved in bacteria
HH204_15245	COG3001	Fructosamine kinase
HH204_15255	COG1105	Belongs to the carbohydrate kinase PfkB family
HH204_15260	COG3137	Salt-induced outer membrane protein
HH204_15300	COG0072	phenylalanine-tRNA ligase activity
HH204_15300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HH204_15320	COG0583	DNA-binding transcription factor activity
HH204_15340	COG0386	Belongs to the glutathione peroxidase family
HH204_15350	COG0791	NLP P60 protein
HH204_15360	COG4256	Hemin uptake protein
HH204_15365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HH204_15380	COG0574	Belongs to the PEP-utilizing enzyme family
HH204_15380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HH204_15395	COG0628	permease
HH204_15400	COG0247	lactate metabolic process
HH204_15400	COG0277	FAD linked oxidase domain protein
HH204_15405	COG2050	protein possibly involved in aromatic compounds catabolism
HH204_15410	COG2261	transglycosylase associated protein
HH204_15435	COG1120	ATPase activity
HH204_15440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_15450	COG0583	DNA-binding transcription factor activity
HH204_15475	COG1304	FMN binding
HH204_15480	COG1309	transcriptional regulator
HH204_15500	COG0316	Belongs to the HesB IscA family
HH204_15505	COG0719	Fe-S assembly protein
HH204_15510	COG0396	ATPase activity
HH204_15515	COG0719	Fe-S assembly protein
HH204_15530	COG1376	ErfK ybiS ycfS ynhG family protein
HH204_15560	COG1309	transcriptional regulator
HH204_15570	COG2271	Major facilitator Superfamily
HH204_15575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HH204_15600	COG1414	Transcriptional regulator
HH204_15635	COG2814	Major facilitator Superfamily
HH204_15655	COG0583	DNA-binding transcription factor activity
HH204_15660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_15680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HH204_15685	COG1116	anion transmembrane transporter activity
HH204_15690	COG4774	siderophore transport
HH204_15695	COG1120	ATPase activity
HH204_15700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_15705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_15725	COG0765	amino acid transport
HH204_15730	COG1126	abc transporter atp-binding protein
HH204_15770	COG3383	formate dehydrogenase (NAD+) activity
HH204_15775	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HH204_15790	COG1175	transmembrane transport
HH204_15825	COG4133	protoheme IX ABC transporter activity
HH204_15830	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HH204_15835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HH204_15850	COG1138	Cytochrome C-type biogenesis protein
HH204_15855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HH204_15860	COG4235	cytochrome complex assembly
HH204_15860	COG3088	subunit of a heme lyase
HH204_15905	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_15910	COG2610	gluconate transmembrane transporter activity
HH204_15915	COG1250	3-hydroxyacyl-CoA dehydrogenase
HH204_15925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HH204_15935	COG0583	DNA-binding transcription factor activity
HH204_15960	COG0277	FAD linked oxidase domain protein
HH204_15965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HH204_15990	COG0402	S-adenosylhomocysteine deaminase activity
HH204_16040	COG2200	EAL domain
HH204_16055	COG2205	protein histidine kinase activity
HH204_16060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_16105	COG4608	Belongs to the ABC transporter superfamily
HH204_16110	COG0444	Belongs to the ABC transporter superfamily
HH204_16135	COG0346	lactoylglutathione lyase activity
HH204_16140	COG1349	DNA-binding transcription factor activity
HH204_16235	COG0307	riboflavin synthase, alpha
HH204_16240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HH204_16245	COG2814	Major facilitator Superfamily
HH204_16250	COG0583	DNA-binding transcription factor activity
HH204_16265	COG2814	Major facilitator Superfamily
HH204_16280	COG0791	NLP P60 protein
HH204_16285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HH204_16295	COG0346	lactoylglutathione lyase activity
HH204_16300	COG1902	pentaerythritol trinitrate reductase activity
HH204_16305	COG1309	transcriptional regulator
HH204_16310	COG3313	Fe-S protein
HH204_16315	COG4989	oxidoreductase activity
HH204_16320	COG2032	superoxide dismutase activity
HH204_16325	COG1289	transmembrane transporter activity
HH204_16330	COG1566	PFAM secretion protein HlyD family protein
HH204_16345	COG3706	GGDEF domain
HH204_16360	COG3895	Periplasmic Protein
HH204_16375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HH204_16380	COG0625	glutathione transferase activity
HH204_16390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HH204_16400	COG4659	FMN binding
HH204_16435	COG2723	6-phospho-beta-galactosidase activity
HH204_16445	COG0673	inositol 2-dehydrogenase activity
HH204_16455	COG2814	Major facilitator Superfamily
HH204_16475	COG3038	cytochrome b561
HH204_16495	COG0583	DNA-binding transcription factor activity
HH204_16500	COG3485	protocatechuate 3,4-dioxygenase
HH204_16505	COG3485	protocatechuate 3,4-dioxygenase
HH204_16510	COG5383	Protein conserved in bacteria
HH204_16515	COG2272	Belongs to the type-B carboxylesterase lipase family
HH204_16535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HH204_16540	COG1275	C4-dicarboxylate transporter malic acid transport protein
HH204_16545	COG0500	methyltransferase
HH204_16560	COG2207	Transcriptional regulator
HH204_16560	COG3708	Transcriptional regulator
HH204_16570	COG1396	sequence-specific DNA binding
HH204_16580	COG0826	peptidase U32
HH204_16600	COG1294	oxidase, subunit
HH204_16605	COG1271	oxidase subunit
HH204_16615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HH204_16620	COG3842	ATPase activity
HH204_16625	COG1176	ABC-type spermidine putrescine transport system, permease component I
HH204_16630	COG1177	transmembrane transport
HH204_16635	COG1012	belongs to the aldehyde dehydrogenase family
HH204_16670	COG1012	belongs to the aldehyde dehydrogenase family
HH204_16680	COG0747	negative chemotaxis
HH204_16690	COG3238	Protein conserved in bacteria
HH204_16695	COG1247	-acetyltransferase
HH204_16705	COG2130	NADP-dependent
HH204_16720	COG3691	Protein conserved in bacteria
HH204_16725	COG1228	amidohydrolase
HH204_16730	COG4772	TonB-dependent receptor
HH204_16755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HH204_16760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_16765	COG1473	amidohydrolase
HH204_16770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_16785	COG0765	amino acid transport
HH204_16790	COG1126	abc transporter atp-binding protein
HH204_16800	COG0625	glutathione transferase activity
HH204_16825	COG2211	Major facilitator Superfamily
HH204_16840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HH204_16845	COG3842	ATPase activity
HH204_16850	COG1840	ABC-type Fe3 transport system, periplasmic component
HH204_16855	COG1178	ABC-type Fe3 transport system permease component
HH204_16860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HH204_16865	COG2181	nitrate reductase activity
HH204_16870	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HH204_16875	COG1140	nitrate reductase beta subunit
HH204_16880	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HH204_16900	COG1414	Transcriptional regulator
HH204_16905	COG4948	Mandelate Racemase Muconate Lactonizing
HH204_16910	COG4829	muconolactone delta-isomerase
HH204_16915	COG3485	protocatechuate 3,4-dioxygenase
HH204_16925	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HH204_16950	COG0437	4 iron, 4 sulfur cluster binding
HH204_16955	COG2864	formate dehydrogenase
HH204_16970	COG2326	polyphosphate kinase activity
HH204_16980	COG2814	Major facilitator Superfamily
HH204_16990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_17010	COG0747	negative chemotaxis
HH204_17015	COG1064	alcohol dehydrogenase
HH204_17030	COG0488	(ABC) transporter
HH204_17070	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_17075	COG3729	General stress protein
HH204_17085	COG3685	Protein conserved in bacteria
HH204_17095	COG0366	Alpha amylase catalytic
HH204_17105	COG2323	membrane
HH204_17115	COG3111	PFAM Bacterial OB fold (BOF) protein
HH204_17125	COG1764	response to oxidative stress
HH204_17150	COG3781	membrane
HH204_17155	COG0243	molybdopterin cofactor binding
HH204_17160	COG0583	DNA-binding transcription factor activity
HH204_17165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_17190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_17195	COG1447	Phosphotransferase system cellobiose-specific component IIA
HH204_17200	COG2814	Major facilitator Superfamily
HH204_17205	COG1285	pathogenesis
HH204_17210	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HH204_17220	COG0583	DNA-binding transcription factor activity
HH204_17240	COG0519	Catalyzes the synthesis of GMP from XMP
HH204_17240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HH204_17280	COG0596	Alpha beta hydrolase
HH204_17285	COG0745	RESPONSE REGULATOR receiver
HH204_17290	COG2205	protein histidine kinase activity
HH204_17305	COG0076	glutamate decarboxylase activity
HH204_17310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HH204_17315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HH204_17320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HH204_17325	COG1116	anion transmembrane transporter activity
HH204_17330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HH204_17345	COG0673	inositol 2-dehydrogenase activity
HH204_17355	COG1609	Transcriptional regulator
HH204_17360	COG3706	GGDEF domain
HH204_17365	COG0402	S-adenosylhomocysteine deaminase activity
HH204_17410	COG0406	alpha-ribazole phosphatase activity
HH204_17415	COG1335	isochorismatase
HH204_17435	COG2207	Transcriptional regulator
HH204_17460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HH204_17485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HH204_17540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HH204_17550	COG2070	2-Nitropropane dioxygenase
HH204_17555	COG0583	DNA-binding transcription factor activity
HH204_17565	COG1902	pentaerythritol trinitrate reductase activity
HH204_17570	COG4529	Protein conserved in bacteria
HH204_17575	COG0477	Major facilitator Superfamily
HH204_17600	COG2223	nitrite transmembrane transporter activity
HH204_17610	COG1609	Transcriptional regulator
HH204_17615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_17625	COG3037	sugar-specific permease SgaT UlaA
HH204_17630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HH204_17640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_17645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_17645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_17645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HH204_17660	COG0583	DNA-binding transcription factor activity
HH204_17665	COG0583	DNA-binding transcription factor activity
HH204_17670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HH204_17680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HH204_17695	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_17705	COG1609	Transcriptional regulator
HH204_17735	COG1652	LysM domain
HH204_17750	COG4977	sequence-specific DNA binding
HH204_17760	COG4977	sequence-specific DNA binding
HH204_17780	COG1349	DNA-binding transcription factor activity
HH204_17790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_17795	COG0738	Major facilitator superfamily
HH204_17830	COG3386	PFAM SMP-30 Gluconolaconase
HH204_17840	COG1929	Belongs to the glycerate kinase type-1 family
HH204_17845	COG3835	regulator
HH204_17855	COG0583	DNA-binding transcription factor activity
HH204_17865	COG2186	Transcriptional regulator
HH204_17870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_17870	COG1263	PTS System
HH204_17885	COG2814	Major facilitator Superfamily
HH204_17890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_17890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_17910	COG2819	hydrolase of the alpha beta superfamily
HH204_17950	COG3188	usher protein
HH204_17965	COG3550	peptidyl-serine autophosphorylation
HH204_17970	COG1396	sequence-specific DNA binding
HH204_17975	COG2351	hydroxyisourate hydrolase activity
HH204_17980	COG3648	Uricase
HH204_17980	COG3195	allantoin biosynthetic process
HH204_17985	COG2233	PERMEase
HH204_18015	COG2207	Transcriptional regulator
HH204_18030	COG4628	conserved protein (DUF2132)
HH204_18050	COG2011	ABC-type metal ion transport system permease component
HH204_18055	COG2070	2-Nitropropane dioxygenase
HH204_18070	COG0477	Major facilitator Superfamily
HH204_18125	COG2199	diguanylate cyclase activity
HH204_18140	COG1012	belongs to the aldehyde dehydrogenase family
HH204_18145	COG0583	DNA-binding transcription factor activity
HH204_18155	COG0039	L-malate dehydrogenase activity
HH204_18160	COG1349	DNA-binding transcription factor activity
HH204_18165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HH204_18170	COG3395	kinase activity
HH204_18180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HH204_18185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HH204_18190	COG2271	Major facilitator Superfamily
HH204_18220	COG4977	sequence-specific DNA binding
HH204_18230	COG0697	spore germination
HH204_18265	COG0683	leucine binding
HH204_18270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HH204_18310	COG2223	nitrite transmembrane transporter activity
HH204_18315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HH204_18330	COG1349	DNA-binding transcription factor activity
HH204_18335	COG2084	Dehydrogenase
HH204_18340	COG3395	kinase activity
HH204_18345	COG0235	Class ii aldolase
HH204_18350	COG3622	Belongs to the hyi family
HH204_18355	COG2610	gluconate transmembrane transporter activity
HH204_18360	COG2207	Transcriptional regulator
HH204_18360	COG3708	Transcriptional regulator
HH204_18375	COG2200	EAL domain
HH204_18380	COG1546	Belongs to the CinA family
HH204_18385	COG0071	Belongs to the small heat shock protein (HSP20) family
HH204_18405	COG2197	response regulator
HH204_18420	COG2135	peptidase activity
HH204_18425	COG2207	Transcriptional regulator
HH204_18440	COG4221	oxidoreductase activity
HH204_18445	COG1802	Transcriptional regulator
HH204_18450	COG0589	response to stress
HH204_18455	COG0246	Mannitol dehydrogenase
HH204_18460	COG2271	Major facilitator Superfamily
HH204_18475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HH204_18490	COG0243	molybdopterin cofactor binding
HH204_18495	COG0437	4 iron, 4 sulfur cluster binding
HH204_18500	COG3302	dmso reductase anchor subunit
HH204_18515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HH204_18520	COG1940	carbohydrate kinase activity
HH204_18525	COG0583	DNA-binding transcription factor activity
HH204_18530	COG2814	Major facilitator Superfamily
HH204_18535	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HH204_18555	COG3591	Belongs to the peptidase S1B family
HH204_18575	COG0628	permease
HH204_18605	COG0679	Auxin Efflux Carrier
HH204_18615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HH204_18640	COG3290	protein histidine kinase activity
HH204_18645	COG4565	transcriptional regulatory protein
HH204_18665	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HH204_18665	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HH204_18675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_18680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HH204_18690	COG0183	Belongs to the thiolase family
HH204_18695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HH204_18710	COG2840	Smr protein MutS2
HH204_18715	COG0583	DNA-binding transcription factor activity
HH204_18725	COG1473	amidohydrolase
HH204_18730	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HH204_18745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HH204_18760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HH204_18765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HH204_18785	COG0531	amino acid
HH204_18795	COG3136	membrane protein required for alginate biosynthesis
HH204_18800	COG0745	RESPONSE REGULATOR receiver
HH204_18810	COG2205	protein histidine kinase activity
HH204_18820	COG0114	fumarate hydratase activity
HH204_18825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HH204_18825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HH204_18830	COG1482	cell wall glycoprotein biosynthetic process
HH204_18835	COG5339	Protein conserved in bacteria
HH204_18840	COG1609	Transcriptional regulator
HH204_18845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HH204_18845	COG1263	PTS System
HH204_18850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HH204_18875	COG2391	methyltransferase activity
HH204_18880	COG0425	Belongs to the sulfur carrier protein TusA family
HH204_18885	COG5562	phage envelope protein
HH204_18890	COG0401	homolog of Blt101
HH204_18895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HH204_18900	COG1012	belongs to the aldehyde dehydrogenase family
HH204_18910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HH204_18915	COG0477	Major facilitator Superfamily
HH204_18920	COG1113	amino acid transport
HH204_18925	COG2988	succinylglutamate desuccinylase activity
HH204_18930	COG3724	N-succinylarginine dihydrolase activity
HH204_18935	COG1012	belongs to the aldehyde dehydrogenase family
HH204_18940	COG3138	arginine N-succinyltransferase
HH204_18945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HH204_18955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HH204_18960	COG0667	Aldo Keto reductase
HH204_18965	COG0583	DNA-binding transcription factor activity
HH204_18990	COG4122	O-methyltransferase activity
HH204_18995	COG1643	Atp-dependent helicase
HH204_19010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HH204_19015	COG3327	negative regulation of DNA-templated transcription, initiation
HH204_19020	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HH204_19025	COG0183	Belongs to the thiolase family
HH204_19030	COG2050	protein possibly involved in aromatic compounds catabolism
HH204_19040	COG1024	Enoyl-CoA hydratase
HH204_19045	COG1024	Enoyl-CoA hydratase
HH204_19050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HH204_19055	COG2151	metal-sulfur cluster biosynthetic enzyme
HH204_19060	COG3396	Phenylacetate-CoA oxygenase
HH204_19065	COG3460	Phenylacetate-CoA oxygenase
HH204_19070	COG3396	Phenylacetate-CoA oxygenase
HH204_19075	COG2030	dehydratase
HH204_19075	COG1012	belongs to the aldehyde dehydrogenase family
HH204_19095	COG1012	belongs to the aldehyde dehydrogenase family
HH204_19100	COG2207	Transcriptional regulator
HH204_19105	COG3784	Protein of unknown function (DUF1318)
HH204_19115	COG2911	Protein conserved in bacteria
HH204_19120	COG0586	Pfam SNARE associated Golgi protein
HH204_19125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HH204_19130	COG3187	Heat shock protein
HH204_19135	COG3042	response to heat
HH204_19140	COG0674	pyruvate-flavodoxin oxidoreductase activity
HH204_19140	COG1013	pyruvate-flavodoxin oxidoreductase activity
HH204_19140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HH204_19140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HH204_19145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HH204_19155	COG0589	response to stress
HH204_19165	COG0513	Belongs to the DEAD box helicase family
HH204_19175	COG1349	DNA-binding transcription factor activity
HH204_19180	COG0673	inositol 2-dehydrogenase activity
HH204_19195	COG2011	ABC-type metal ion transport system permease component
HH204_19215	COG0604	alcohol dehydrogenase
HH204_19245	COG0583	DNA-binding transcription factor activity
HH204_19265	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_19270	COG1309	transcriptional regulator
HH204_19275	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_19335	COG2801	Transposase and inactivated derivatives
HH204_19340	COG2963	transposase activity
HH204_19345	COG2963	transposase activity
HH204_19355	COG1705	Flagellar rod assembly protein muramidase FlgJ
HH204_19355	COG1388	LysM domain
HH204_19380	COG2885	chlorophyll binding
HH204_19460	COG1196	nuclear chromosome segregation
HH204_19555	COG3728	DNA packaging
HH204_19555	COG5484	DNA packaging
HH204_19595	COG0484	heat shock protein binding
HH204_19605	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HH204_19615	COG1484	DNA-dependent DNA replication
HH204_19715	COG0582	viral genome integration into host DNA
HH204_19720	COG0693	protein deglycase activity
HH204_19725	COG1078	dGTPase activity
HH204_19730	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_19735	COG0583	DNA-binding transcription factor activity
HH204_19800	COG3250	beta-galactosidase activity
HH204_19805	COG0656	L-ascorbic acid biosynthetic process
HH204_19835	COG4166	transmembrane transport
HH204_19845	COG2866	Carboxypeptidase
HH204_19850	COG4948	Mandelate Racemase Muconate Lactonizing
HH204_19855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HH204_19860	COG3180	Ammonia monooxygenase
HH204_19870	COG1486	melibiose metabolic process
HH204_19875	COG0583	DNA-binding transcription factor activity
HH204_19885	COG3106	COG3106 Predicted ATPase
HH204_19895	COG1983	PspC domain protein
HH204_19905	COG1842	Phage shock protein A
HH204_19910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HH204_19920	COG1473	amidohydrolase
HH204_19935	COG0702	epimerase
HH204_19950	COG4171	peptide transport system, permease
HH204_19965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HH204_19975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HH204_19980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_19980	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_19995	COG1349	DNA-binding transcription factor activity
HH204_20010	COG0023	Translation Initiation Factor
HH204_20020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HH204_20025	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HH204_20030	COG0671	phosphoesterase, PA-phosphatase related
HH204_20040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HH204_20065	COG0616	signal peptide processing
HH204_20075	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_20080	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HH204_20090	COG0583	DNA-binding transcription factor activity
HH204_20100	COG0009	L-threonylcarbamoyladenylate synthase
HH204_20110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HH204_20115	COG0512	Glutamine amidotransferase of anthranilate synthase
HH204_20115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HH204_20120	COG0134	indole-3-glycerol-phosphate synthase activity
HH204_20120	COG0135	phosphoribosylanthranilate isomerase activity
HH204_20175	COG4774	siderophore transport
HH204_20185	COG3047	cAMP biosynthetic process
HH204_20190	COG0727	PFAM Uncharacterised protein family (UPF0153)
HH204_20220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HH204_20225	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_20230	COG1988	membrane-bound metal-dependent
HH204_20255	COG1486	melibiose metabolic process
HH204_20260	COG1917	Cupin 2, conserved barrel domain protein
HH204_20260	COG2169	Transcriptional regulator
HH204_20265	COG1447	Phosphotransferase system cellobiose-specific component IIA
HH204_20270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_20280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HH204_20285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HH204_20295	COG0322	excinuclease ABC activity
HH204_20300	COG3678	ATP-independent chaperone mediated protein folding
HH204_20310	COG3724	N-succinylarginine dihydrolase activity
HH204_20320	COG3138	arginine N-succinyltransferase
HH204_20330	COG0708	Exodeoxyribonuclease III
HH204_20335	COG0398	Pfam SNARE associated Golgi protein
HH204_20340	COG0398	Pfam SNARE associated Golgi protein
HH204_20345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HH204_20350	COG4134	Bacterial extracellular solute-binding protein
HH204_20355	COG4135	transport system, permease component
HH204_20360	COG4136	ATPase activity
HH204_20370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HH204_20375	COG0494	nUDIX hydrolase
HH204_20380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HH204_20385	COG0604	alcohol dehydrogenase
HH204_20385	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_20385	COG3321	synthase
HH204_20390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HH204_20395	COG0709	Synthesizes selenophosphate from selenide and ATP
HH204_20405	COG0778	Nitroreductase
HH204_20410	COG0616	signal peptide processing
HH204_20415	COG0252	asparaginase activity
HH204_20420	COG1335	isochorismatase
HH204_20435	COG3139	Protein of unknown function (DUF1315)
HH204_20455	COG0656	L-ascorbic acid biosynthetic process
HH204_20460	COG3713	MltA-interacting MipA family protein
HH204_20465	COG2766	serine protein kinase
HH204_20480	COG0386	Belongs to the glutathione peroxidase family
HH204_20505	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_20510	COG0583	DNA-binding transcription factor activity
HH204_20515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HH204_20520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HH204_20530	COG0859	PFAM glycosyl transferase family 9
HH204_20535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HH204_20545	COG2207	Transcriptional regulator
HH204_20550	COG2807	transmembrane transport
HH204_20555	COG0504	CTP synthase activity
HH204_20560	COG1683	Conserved Protein
HH204_20565	COG3189	MarR family transcriptional regulator
HH204_20570	COG3042	response to heat
HH204_20575	COG2203	Gaf domain
HH204_20575	COG2199	diguanylate cyclase activity
HH204_20595	COG3182	Iron-regulated membrane protein
HH204_20605	COG1560	Kdo2-lipid A biosynthetic process
HH204_20620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HH204_20625	COG3706	GGDEF domain
HH204_20630	COG0583	DNA-binding transcription factor activity
HH204_20665	COG1294	oxidase, subunit
HH204_20670	COG1271	oxidase subunit
HH204_20675	COG3546	catalase activity
HH204_20680	COG3685	Protein conserved in bacteria
HH204_20685	COG3685	Protein conserved in bacteria
HH204_20690	COG3729	General stress protein
HH204_20700	COG1063	alcohol dehydrogenase
HH204_20705	COG3813	Protein conserved in bacteria
HH204_20725	COG0640	Transcriptional regulator
HH204_20730	COG0538	isocitrate dehydrogenase activity
HH204_20735	COG1187	pseudouridine synthase activity
HH204_20755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HH204_20775	COG2205	protein histidine kinase activity
HH204_20780	COG2850	peptidyl-arginine hydroxylation
HH204_20785	COG1943	Transposase
HH204_20805	COG1177	transmembrane transport
HH204_20830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HH204_20835	COG0698	ribose 5-phosphate isomerase
HH204_20850	COG3395	kinase activity
HH204_20865	COG2390	Transcriptional regulator
HH204_20875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HH204_20885	COG4591	ABC-type transport system involved in lipoprotein release permease component
HH204_20895	COG4591	ABC-type transport system involved in lipoprotein release permease component
HH204_20910	COG1388	LysM domain
HH204_20910	COG1376	ErfK ybiS ycfS ynhG family protein
HH204_20925	COG1309	transcriptional regulator
HH204_20940	COG3134	Outer membrane lipoprotein
HH204_20945	COG1252	NADH dehydrogenase
HH204_20970	COG5633	Lipoprotein
HH204_20975	COG0537	adenosine 5'-monophosphoramidase activity
HH204_20985	COG0084	hydrolase, TatD family'
HH204_20990	COG0470	DNA polymerase III
HH204_21000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HH204_21005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HH204_21010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HH204_21025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HH204_21045	COG1399	metal-binding, possibly nucleic acid-binding protein
HH204_21065	COG1530	ribonuclease E activity
HH204_21070	COG0583	DNA-binding transcription factor activity
HH204_21075	COG2814	Major facilitator Superfamily
HH204_21095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HH204_21145	COG1560	Kdo2-lipid A biosynthetic process
HH204_21160	COG5645	(Lipo)protein
HH204_21195	COG3381	protein complex oligomerization
HH204_21220	COG0583	DNA-binding transcription factor activity
HH204_21230	COG1335	isochorismatase
HH204_21240	COG1702	phosphate starvation-inducible protein PhoH
HH204_21260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HH204_21275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HH204_21290	COG1309	transcriptional regulator
HH204_21325	COG2233	PERMEase
HH204_21335	COG3729	General stress protein
HH204_21365	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_21380	COG0531	amino acid
HH204_21385	COG0174	glutamine synthetase
HH204_21390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HH204_21395	COG1917	Cupin 2, conserved barrel domain protein
HH204_21395	COG1396	sequence-specific DNA binding
HH204_21400	COG1012	belongs to the aldehyde dehydrogenase family
HH204_21405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HH204_21410	COG0583	DNA-binding transcription factor activity
HH204_21415	COG0473	3-isopropylmalate dehydrogenase activity
HH204_21420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HH204_21425	COG4638	Rieske (2fe-2S)
HH204_21430	COG1012	belongs to the aldehyde dehydrogenase family
HH204_21435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HH204_21440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HH204_21440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_21440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_21445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_21450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_21455	COG1882	Formate acetyltransferase
HH204_21460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HH204_21465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HH204_21475	COG2207	Transcriptional regulator
HH204_21480	COG3706	GGDEF domain
HH204_21500	COG2200	EAL domain
HH204_21510	COG0058	SHG alpha-glucan phosphorylase activity
HH204_21525	COG0670	Belongs to the BI1 family
HH204_21540	COG2207	Transcriptional regulator
HH204_21545	COG1881	PFAM PEBP family protein
HH204_21560	COG1832	CoA-binding protein
HH204_21570	COG0210	DNA helicase
HH204_21575	COG3304	Inner membrane component domain
HH204_21580	COG1289	transmembrane transporter activity
HH204_21585	COG3070	regulator of competence-specific genes
HH204_21605	COG1067	ATP-dependent peptidase activity
HH204_21615	COG3130	regulation of translation
HH204_21620	COG3009	Protein conserved in bacteria
HH204_21625	COG3008	intermembrane lipid transfer
HH204_21625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HH204_21630	COG2995	paraquat-inducible protein a
HH204_21635	COG0488	(ABC) transporter
HH204_21645	COG3217	Mosc domain protein beta barrel domain protein
HH204_21645	COG0633	Ferredoxin
HH204_21660	COG0431	NADPH-dependent FMN reductase
HH204_21665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HH204_21670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HH204_21675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HH204_21685	COG0308	aminopeptidase N
HH204_21695	COG1473	amidohydrolase
HH204_21705	COG0814	amino acid
HH204_21725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HH204_21730	COG1448	Aminotransferase
HH204_21735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HH204_21740	COG3108	Peptidase M15
HH204_21745	COG2989	Protein conserved in bacteria
HH204_21755	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HH204_21765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HH204_21770	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HH204_21775	COG3173	Aminoglycoside phosphotransferase
HH204_21790	COG3214	Protein conserved in bacteria
HH204_21805	COG2333	competence protein COMEC
HH204_21805	COG0658	competence protein
HH204_21815	COG0539	negative regulation of cytoplasmic translation
HH204_21835	COG2323	membrane
HH204_21840	COG1944	ATP diphosphatase activity
HH204_21845	COG2116	formate transmembrane transporter activity
HH204_21850	COG1882	Formate acetyltransferase
HH204_21855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HH204_21860	COG0477	Major facilitator Superfamily
HH204_21870	COG3302	dmso reductase anchor subunit
HH204_21875	COG0437	4 iron, 4 sulfur cluster binding
HH204_21880	COG0243	molybdopterin cofactor binding
HH204_21890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HH204_21900	COG1178	ABC-type Fe3 transport system permease component
HH204_21900	COG1674	ftsk spoiiie
HH204_21915	COG0492	ferredoxin-NADP+ reductase activity
HH204_21920	COG4988	ABC transporter
HH204_21925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HH204_21940	COG0542	response to heat
HH204_21950	COG1278	Cold shock
HH204_21960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_21965	COG3593	DNA synthesis involved in DNA repair
HH204_21975	COG2431	L-lysine efflux transmembrane transporter activity
HH204_21985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HH204_21995	COG0028	Belongs to the TPP enzyme family
HH204_22000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HH204_22005	COG0702	epimerase
HH204_22010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HH204_22015	COG3023	N-Acetylmuramoyl-L-alanine amidase
HH204_22020	COG5001	Diguanylate cyclase
HH204_22020	COG4251	negative regulation of phosphorylation
HH204_22020	COG3706	GGDEF domain
HH204_22020	COG2203	Gaf domain
HH204_22030	COG1126	abc transporter atp-binding protein
HH204_22035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_22040	COG4215	(ABC) transporter
HH204_22045	COG4160	amino acid transport
HH204_22050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_22055	COG5002	protein histidine kinase activity
HH204_22060	COG0745	RESPONSE REGULATOR receiver
HH204_22075	COG1177	transmembrane transport
HH204_22080	COG1176	ABC-type spermidine putrescine transport system, permease component I
HH204_22085	COG3842	ATPase activity
HH204_22090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HH204_22105	COG0778	Nitroreductase
HH204_22150	COG3226	Transcriptional regulator
HH204_22155	COG0738	Major facilitator superfamily
HH204_22160	COG0561	phosphatase activity
HH204_22165	COG2814	Major facilitator Superfamily
HH204_22170	COG0671	phosphoesterase, PA-phosphatase related
HH204_22175	COG1349	DNA-binding transcription factor activity
HH204_22180	COG1686	Belongs to the peptidase S11 family
HH204_22190	COG0625	glutathione transferase activity
HH204_22195	COG2133	pyrroloquinoline quinone binding
HH204_22205	COG2223	nitrite transmembrane transporter activity
HH204_22225	COG0747	negative chemotaxis
HH204_22240	COG0303	'Molybdopterin
HH204_22245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HH204_22250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HH204_22255	COG1882	Formate acetyltransferase
HH204_22260	COG0561	phosphatase activity
HH204_22270	COG1609	Transcriptional regulator
HH204_22275	COG2271	Major facilitator Superfamily
HH204_22285	COG0488	(ABC) transporter
HH204_22290	COG2365	Tyrosine phosphatase family
HH204_22295	COG1376	ErfK ybiS ycfS ynhG family protein
HH204_22300	COG2188	Transcriptional regulator
HH204_22305	COG2723	6-phospho-beta-galactosidase activity
HH204_22310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HH204_22325	COG2194	sulfuric ester hydrolase activity
HH204_22330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HH204_22350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_22355	COG0765	amino acid transport
HH204_22360	COG1126	abc transporter atp-binding protein
HH204_22365	COG0668	transmembrane transport
HH204_22375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HH204_22385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HH204_22395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HH204_22400	COG1199	ATP-dependent helicase activity
HH204_22405	COG0513	Belongs to the DEAD box helicase family
HH204_22410	COG3958	Transketolase
HH204_22415	COG3959	Transketolase, thiamine diphosphate binding domain
HH204_22420	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_22435	COG0583	DNA-binding transcription factor activity
HH204_22440	COG1309	transcriptional regulator
HH204_22445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_22450	COG1131	(ABC) transporter
HH204_22455	COG0842	Transport permease protein
HH204_22460	COG0842	Transport permease protein
HH204_22470	COG3568	Endonuclease Exonuclease Phosphatase
HH204_22475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HH204_22480	COG0392	lysyltransferase activity
HH204_22490	COG0670	Belongs to the BI1 family
HH204_22495	COG0314	molybdopterin synthase activity
HH204_22500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HH204_22510	COG0521	Mo-molybdopterin cofactor biosynthetic process
HH204_22530	COG0745	RESPONSE REGULATOR receiver
HH204_22535	COG0642	Histidine kinase
HH204_22560	COG2226	methyltransferase
HH204_22575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HH204_22580	COG1881	PFAM PEBP family protein
HH204_22620	COG4677	pectinesterase activity
HH204_22630	COG0589	response to stress
HH204_22635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_22640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HH204_22670	COG0789	Transcriptional regulator
HH204_22675	COG2200	EAL domain
HH204_22700	COG0561	phosphatase activity
HH204_22710	COG4149	molybdate abc transporter
HH204_22715	COG0725	ABC transporter, periplasmic molybdate-binding protein
HH204_22725	COG2005	Transcriptional regulator
HH204_22725	COG3585	molybdate ion transport
HH204_22735	COG1119	ATPase activity
HH204_22745	COG1085	galactose-1-phosphate uridylyltransferase
HH204_22755	COG2017	converts alpha-aldose to the beta-anomer
HH204_22765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HH204_22780	COG3201	nicotinamide mononucleotide transporter
HH204_22785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HH204_22820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HH204_22825	COG2885	chlorophyll binding
HH204_22835	COG3064	Membrane
HH204_22840	COG0848	biopolymer transport protein
HH204_22845	COG0811	peptide transport
HH204_22850	COG0824	Thioesterase
HH204_22855	COG3790	cyd operon protein YbgE
HH204_22860	COG4890	Cyd operon protein YbgT
HH204_22865	COG1294	oxidase, subunit
HH204_22870	COG1271	oxidase subunit
HH204_22880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HH204_22890	COG0508	dehydrogenase complex catalyzes the overall conversion of
HH204_22895	COG0567	Dehydrogenase, E1 component
HH204_22900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HH204_22905	COG1053	succinate dehydrogenase
HH204_22910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HH204_22915	COG2009	succinate dehydrogenase
HH204_22950	COG1984	allophanate hydrolase subunit 2
HH204_22955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HH204_22970	COG0415	Belongs to the DNA photolyase family
HH204_23000	COG2205	protein histidine kinase activity
HH204_23005	COG0745	RESPONSE REGULATOR receiver
HH204_23015	COG0033	Phosphoglucomutase
HH204_23025	COG0596	Alpha beta hydrolase
HH204_23040	COG0735	belongs to the Fur family
HH204_23080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HH204_23085	COG1940	carbohydrate kinase activity
HH204_23085	COG1846	Transcriptional regulator
HH204_23090	COG0647	UMP catabolic process
HH204_23095	COG0367	asparagine synthase
HH204_23135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HH204_23145	COG1702	phosphate starvation-inducible protein PhoH
HH204_23170	COG0765	amino acid transport
HH204_23175	COG0765	amino acid transport
HH204_23180	COG1126	abc transporter atp-binding protein
HH204_23195	COG2888	peptidyl-tyrosine sulfation
HH204_23210	COG1466	dna polymerase III delta subunit
HH204_23225	COG0799	negative regulation of ribosome biogenesis
HH204_23235	COG0768	penicillin binding
HH204_23240	COG0772	Belongs to the SEDS family
HH204_23245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HH204_23250	COG1686	Belongs to the peptidase S11 family
HH204_23265	COG0583	DNA-binding transcription factor activity
HH204_23280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HH204_23300	COG3069	C4-dicarboxylate transmembrane transporter activity
HH204_23305	COG3719	Belongs to the RNase T2 family
HH204_23310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HH204_23330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HH204_23335	COG0583	DNA-binding transcription factor activity
HH204_23340	COG3969	phosphoadenosine phosphosulfate
HH204_23345	COG1475	DNA binding
HH204_23350	COG0436	Aminotransferase
HH204_23375	COG1129	ABC transporter
HH204_23380	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_23385	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_23395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HH204_23410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HH204_23420	COG0402	S-adenosylhomocysteine deaminase activity
HH204_23430	COG0483	inositol monophosphate 1-phosphatase activity
HH204_23435	COG2271	Major facilitator Superfamily
HH204_23465	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_23470	COG1129	ABC transporter
HH204_23475	COG0371	Dehydrogenase
HH204_23480	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_23495	COG2879	small protein
HH204_23500	COG1966	Carbon starvation protein
HH204_23510	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_23515	COG1535	isochorismatase
HH204_23515	COG3433	isochorismatase activity
HH204_23520	COG1021	2,3-dihydroxybenzoate-AMP ligase
HH204_23525	COG1169	isochorismate synthase
HH204_23530	COG4592	Periplasmic binding protein
HH204_23540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_23545	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_23550	COG1120	ATPase activity
HH204_23555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HH204_23555	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HH204_23560	COG3251	PFAM MbtH domain protein
HH204_23565	COG2382	esterase
HH204_23570	COG4771	TonB-dependent receptor
HH204_23580	COG1879	ABC-type sugar transport system periplasmic component
HH204_23590	COG1129	ABC transporter
HH204_23595	COG1172	Belongs to the binding-protein-dependent transport system permease family
HH204_23600	COG5464	transposase or invertase
HH204_23605	COG2390	Transcriptional regulator
HH204_23610	COG3959	Transketolase, thiamine diphosphate binding domain
HH204_23615	COG3958	Transketolase
HH204_23625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HH204_23640	COG0583	DNA-binding transcription factor activity
HH204_23645	COG0668	transmembrane transport
HH204_23655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HH204_23680	COG0747	negative chemotaxis
HH204_23685	COG0601	transmembrane transport
HH204_23690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HH204_23700	COG4608	Belongs to the ABC transporter superfamily
HH204_23710	COG4221	oxidoreductase activity
HH204_23720	COG4215	(ABC) transporter
HH204_23725	COG0765	amino acid transport
HH204_23730	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HH204_23745	COG0697	spore germination
HH204_23760	COG4608	Belongs to the ABC transporter superfamily
HH204_23765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HH204_23785	COG3698	Phosphodiester glycosidase
HH204_23830	COG2315	Protein conserved in bacteria
HH204_23835	COG0778	Nitroreductase
HH204_23865	COG0477	Major facilitator Superfamily
HH204_23870	COG0668	transmembrane transport
HH204_23885	COG0673	inositol 2-dehydrogenase activity
HH204_23895	COG2211	Major facilitator Superfamily
HH204_23900	COG1113	amino acid transport
HH204_23915	COG1012	belongs to the aldehyde dehydrogenase family
HH204_23920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HH204_23930	COG0531	amino acid
HH204_23945	COG4680	protein conserved in bacteria
HH204_23985	COG0667	Aldo Keto reductase
HH204_23990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_23995	COG1473	amidohydrolase
HH204_24030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_24035	COG1120	ATPase activity
HH204_24040	COG1566	PFAM secretion protein HlyD family protein
HH204_24095	COG4211	Belongs to the binding-protein-dependent transport system permease family
HH204_24100	COG1129	ABC transporter
HH204_24115	COG0673	inositol 2-dehydrogenase activity
HH204_24145	COG3104	oligopeptide transport
HH204_24150	COG1982	Orn Lys Arg decarboxylase major
HH204_24155	COG0531	amino acid
HH204_24170	COG1560	Kdo2-lipid A biosynthetic process
HH204_24310	COG3561	AntA/AntB antirepressor
HH204_24330	COG0582	viral genome integration into host DNA
HH204_24345	COG2501	S4 domain
HH204_24355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HH204_24370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HH204_24375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HH204_24395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HH204_24400	COG4181	ATPase activity
HH204_24405	COG2755	lipolytic protein G-D-S-L family
HH204_24410	COG0300	oxidoreductase activity
HH204_24415	COG3118	belongs to the thioredoxin family
HH204_24420	COG0390	transport system, permease component
HH204_24425	COG4619	ABC transporter
HH204_24430	COG0330	HflC and HflK could
HH204_24435	COG1585	Membrane protein implicated in regulation of membrane protease activity
HH204_24450	COG3735	TraB family
HH204_24455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HH204_24465	COG2223	nitrite transmembrane transporter activity
HH204_24480	COG4651	solute:proton antiporter activity
HH204_24480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HH204_24485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_24525	COG2832	Protein of unknown function (DUF454)
HH204_24530	COG3923	Primosomal replication protein n
HH204_24545	COG1196	nuclear chromosome segregation
HH204_24545	COG3264	Mechanosensitive ion channel
HH204_24555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_24560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HH204_24575	COG0110	maltose O-acetyltransferase activity
HH204_24625	COG1874	Beta-galactosidase
HH204_24630	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HH204_24635	COG3833	ABC-type maltose transport systems, permease component
HH204_24645	COG2182	Extracellular solute-binding protein
HH204_24660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HH204_24705	COG3695	enzyme binding
HH204_24710	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HH204_24715	COG1946	Acyl-CoA thioesterase
HH204_24720	COG0004	ammonium transporteR
HH204_24725	COG0347	Belongs to the P(II) protein family
HH204_24730	COG1132	(ABC) transporter
HH204_24735	COG1132	(ABC) transporter
HH204_24740	COG1522	sequence-specific DNA binding
HH204_24755	COG4533	DNA binding
HH204_24765	COG0824	Thioesterase
HH204_24770	COG1555	photosystem II stabilization
HH204_24775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HH204_24780	COG0776	regulation of translation
HH204_24785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HH204_24810	COG0271	Belongs to the BolA IbaG family
HH204_24815	COG3056	Lipoprotein
HH204_24820	COG2223	nitrite transmembrane transporter activity
HH204_24825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HH204_24830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HH204_24835	COG1845	cytochrome c oxidase, subunit III
HH204_24840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HH204_24855	COG1414	Transcriptional regulator
HH204_24860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HH204_24875	COG1053	succinate dehydrogenase
HH204_24890	COG0673	inositol 2-dehydrogenase activity
HH204_24895	COG2814	Major facilitator Superfamily
HH204_24905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HH204_24930	COG0142	geranyltranstransferase activity
HH204_24940	COG0667	Aldo Keto reductase
HH204_24945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HH204_24965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HH204_24965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HH204_24975	COG4238	major outer membrane lipoprotein
HH204_24995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HH204_25000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HH204_25005	COG1862	Preprotein translocase
HH204_25030	COG0450	alkyl hydroperoxide reductase
HH204_25035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_25050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HH204_25060	COG1228	amidohydrolase
HH204_25070	COG1335	isochorismatase
HH204_25075	COG0583	DNA-binding transcription factor activity
HH204_25080	COG0366	Alpha amylase catalytic
HH204_25105	COG0420	3'-5' exonuclease activity
HH204_25110	COG0419	ATPase involved in DNA repair
HH204_25115	COG1940	carbohydrate kinase activity
HH204_25130	COG4126	flavin adenine dinucleotide binding
HH204_25140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HH204_25145	COG3416	Protein conserved in bacteria
HH204_25155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HH204_25165	COG1785	Belongs to the alkaline phosphatase family
HH204_25205	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HH204_25210	COG1335	isochorismatase
HH204_25215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HH204_25220	COG0113	porphobilinogen synthase activity
HH204_25225	COG1943	Transposase
HH204_25235	COG2175	clavaminate synthase activity
HH204_25240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HH204_25245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HH204_25250	COG4521	taurine ABC transporter
HH204_25255	COG2040	homocysteine
HH204_25260	COG0833	amino acid
HH204_25275	COG4303	Ethanolamine ammonia lyase large subunit
HH204_25280	COG4302	ethanolamine ammonia-lyase activity
HH204_25320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HH204_25325	COG1126	abc transporter atp-binding protein
HH204_25330	COG4597	amino acid ABC transporter
HH204_25335	COG0765	amino acid transport
HH204_25375	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HH204_25385	COG3639	organic phosphonate transmembrane transporter activity
HH204_25405	COG0791	NLP P60 protein
HH204_25440	COG3188	usher protein
HH204_25445	COG3121	Chaperone
HH204_25450	COG3539	Fimbrial protein
HH204_25465	COG3710	Transcriptional regulator
HH204_25495	COG2200	EAL domain
HH204_25515	COG3121	Chaperone
HH204_25540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HH204_25555	COG0579	oxidoreductase
HH204_25560	COG1012	belongs to the aldehyde dehydrogenase family
HH204_25565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HH204_25570	COG1113	amino acid transport
HH204_25575	COG1802	Transcriptional regulator
HH204_25585	COG0583	DNA-binding transcription factor activity
HH204_25595	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_25625	COG2195	Cleaves the N-terminal amino acid of tripeptides
HH204_25630	COG0454	-acetyltransferase
HH204_25645	COG2991	Protein conserved in bacteria
HH204_25660	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HH204_25665	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HH204_25680	COG3034	peptidoglycan biosynthetic process
HH204_25685	COG0121	glutamine amidotransferase
HH204_25695	COG1960	acyl-CoA dehydrogenase activity
HH204_25700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HH204_25710	COG0583	DNA-binding transcription factor activity
HH204_25720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HH204_25730	COG2226	methyltransferase
HH204_25740	COG1388	LysM domain
HH204_25740	COG0741	lytic transglycosylase activity
HH204_25745	COG2226	methyltransferase
HH204_25755	COG2814	Major facilitator Superfamily
HH204_25760	COG0583	DNA-binding transcription factor activity
HH204_25765	COG0656	L-ascorbic acid biosynthetic process
HH204_25800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HH204_25810	COG2011	ABC-type metal ion transport system permease component
HH204_25815	COG1464	Belongs to the NlpA lipoprotein family
HH204_25825	COG1720	tRNA m6t6A37 methyltransferase activity
HH204_25835	COG0791	NLP P60 protein
HH204_25840	COG3015	lipoprotein NlpE involved in copper resistance
HH204_25845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HH204_25860	COG4568	rho-dependent transcription termination
HH204_25870	COG0346	lactoylglutathione lyase activity
HH204_25885	COG0587	DNA-directed DNA polymerase activity
HH204_25915	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HH204_25925	COG0750	zinc metalloprotease
HH204_25930	COG0575	Belongs to the CDS family
HH204_25940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HH204_25965	COG0024	Methionine aminopeptidase
HH204_25970	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HH204_25985	COG3835	regulator
HH204_25990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HH204_26010	COG2860	membrane
HH204_26030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_26035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HH204_26040	COG1120	ATPase activity
HH204_26045	COG4774	siderophore transport
HH204_26050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HH204_26145	COG1643	Atp-dependent helicase
HH204_26150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HH204_26170	COG0617	tRNA 3'-terminal CCA addition
HH204_26175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HH204_26195	COG0726	polysaccharide deacetylase
HH204_26200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HH204_26205	COG0842	Transport permease protein
HH204_26210	COG1131	(ABC) transporter
HH204_26215	COG0288	reversible hydration of carbon dioxide
HH204_26230	COG4993	Dehydrogenase
HH204_26235	COG2132	Multicopper oxidase
HH204_26300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HH204_26305	COG0508	dehydrogenase complex catalyzes the overall conversion of
HH204_26310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HH204_26315	COG2186	Transcriptional regulator
HH204_26320	COG1113	amino acid transport
HH204_26325	COG2211	Major facilitator Superfamily
HH204_26330	COG3940	Belongs to the glycosyl hydrolase 43 family
HH204_26335	COG3725	Membrane protein required for beta-lactamase induction
HH204_26340	COG3023	N-Acetylmuramoyl-L-alanine amidase
HH204_26350	COG4969	Belongs to the N-Me-Phe pilin family
HH204_26355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HH204_26360	COG1459	type II secretion system
HH204_26385	COG0494	nUDIX hydrolase
HH204_26405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HH204_26410	COG0849	cell division
HH204_26435	COG0772	Belongs to the SEDS family
HH204_26535	COG3321	synthase
HH204_26535	COG1028	Short-chain dehydrogenase reductase Sdr
HH204_26535	COG0604	alcohol dehydrogenase
HH204_26550	COG1522	sequence-specific DNA binding
HH204_26710	COG0523	cobalamin synthesis protein
HH204_26715	COG0500	methyltransferase
HH204_26730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HH204_26740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HH204_26775	COG3706	GGDEF domain
HH204_26810	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HH204_26850	COG0739	heme binding
HH204_26860	COG2132	Multicopper oxidase
HH204_26865	COG3667	copper resistance
HH204_26870	COG2372	response to copper ion
HH204_26875	COG1276	copper resistance
HH204_26880	COG0745	RESPONSE REGULATOR receiver
HH204_26885	COG2205	protein histidine kinase activity
HH204_26890	COG0789	Transcriptional regulator
HH204_26905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HH204_26955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HH204_26995	COG0523	cobalamin synthesis protein
HH204_27025	COG2916	Histone family protein nucleoid-structuring protein H-NS
HH204_27045	COG5654	RES domain protein
HH204_27050	COG5642	Protein of unknown function (DUF2384)
HH204_27065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HH204_27070	COG4772	TonB-dependent receptor
HH204_27080	COG1595	DNA-templated transcription, initiation
HH204_27095	COG3969	phosphoadenosine phosphosulfate
HH204_27100	COG1475	DNA binding
HH204_27120	COG2382	esterase
HH204_27155	COG0500	methyltransferase
HH204_27305	COG3436	PFAM IS66 Orf2 family protein
HH204_27310	COG4372	Transposase
HH204_27395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HH204_27420	COG2144	transferase activity, transferring acyl groups
HH204_27435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HH204_27455	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
HH204_27480	COG4245	von Willebrand factor, type A
HH204_27485	COG4245	von Willebrand factor, type A
HH204_27495	COG4245	von Willebrand factor, type A