locus-tag	class	description
GXN76_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GXN76_00010	COG0592	DNA-directed DNA polymerase activity
GXN76_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GXN76_00030	COG0187	DNA topoisomerase II activity
GXN76_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GXN76_00045	COG0833	amino acid
GXN76_00050	COG1131	(ABC) transporter
GXN76_00055	COG1725	Transcriptional regulator
GXN76_00070	COG1668	transmembrane transport
GXN76_00075	COG4555	ABC transporter
GXN76_00080	COG0517	IMP dehydrogenase activity
GXN76_00080	COG0516	GMP reductase activity
GXN76_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GXN76_00105	COG0351	phosphomethylpyrimidine kinase
GXN76_00135	COG1515	deoxyribonuclease V activity
GXN76_00145	COG0367	asparagine synthase
GXN76_00160	COG1309	transcriptional regulator
GXN76_00165	COG1511	domain protein
GXN76_00170	COG1121	(ABC) transporter
GXN76_00175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GXN76_00180	COG0735	belongs to the Fur family
GXN76_00185	COG0590	tRNA wobble adenosine to inosine editing
GXN76_00215	COG1280	lysine exporter protein (LysE YggA)
GXN76_00245	COG2226	methyltransferase
GXN76_00255	COG1129	ABC transporter
GXN76_00270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GXN76_00280	COG0655	NAD(P)H dehydrogenase (quinone) activity
GXN76_00295	COG4191	Histidine kinase
GXN76_00300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GXN76_00305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GXN76_00310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GXN76_00315	COG1266	CAAX protease self-immunity
GXN76_00345	COG1982	Orn Lys Arg decarboxylase major
GXN76_00350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GXN76_00355	COG3870	Protein conserved in bacteria
GXN76_00360	COG0470	DNA polymerase III
GXN76_00365	COG1774	PSP1 C-terminal conserved region
GXN76_00370	COG4467	Involved in initiation control of chromosome replication
GXN76_00380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GXN76_00385	COG2190	(PTS) system
GXN76_00385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXN76_00385	COG1263	PTS System
GXN76_00390	COG2002	toxin-antitoxin pair type II binding
GXN76_00415	COG0084	hydrolase, TatD family'
GXN76_00420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GXN76_00425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GXN76_00430	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GXN76_00435	COG4466	Protein conserved in bacteria
GXN76_00440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GXN76_00445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GXN76_00455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GXN76_00460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GXN76_00465	COG0251	oxidation-reduction process
GXN76_00470	COG2088	sporulation resulting in formation of a cellular spore
GXN76_00475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GXN76_00485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GXN76_00500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GXN76_00510	COG2002	toxin-antitoxin pair type II binding
GXN76_00515	COG2244	polysaccharide biosynthetic process
GXN76_00520	COG3956	TIGRFAM MazG family protein
GXN76_00525	COG0776	regulation of translation
GXN76_00530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GXN76_00550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GXN76_00555	COG3876	Protein conserved in bacteria
GXN76_00570	COG3557	Belongs to the UPF0374 family
GXN76_00575	COG2208	phosphoserine phosphatase activity
GXN76_00580	COG0037	tRNA processing
GXN76_00590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXN76_00600	COG0697	spore germination
GXN76_00680	COG0431	NADPH-dependent FMN reductase
GXN76_00685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GXN76_00690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXN76_00695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GXN76_00700	COG1116	anion transmembrane transporter activity
GXN76_00705	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GXN76_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GXN76_00715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GXN76_00720	COG0512	Glutamine amidotransferase of anthranilate synthase
GXN76_00725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GXN76_00730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GXN76_00735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GXN76_00740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GXN76_00745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GXN76_00750	COG0584	glycerophosphoryl diester phosphodiesterase
GXN76_00875	COG0681	Belongs to the peptidase S26 family
GXN76_00880	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GXN76_00915	COG2304	oxidoreductase activity
GXN76_00925	COG4942	peptidase
GXN76_00930	COG3584	3D domain protein
GXN76_00960	COG2304	oxidoreductase activity
GXN76_00980	COG2304	oxidoreductase activity
GXN76_00985	COG2304	oxidoreductase activity
GXN76_00995	COG2304	oxidoreductase activity
GXN76_01025	COG0137	argininosuccinate synthase activity
GXN76_01030	COG0165	Argininosuccinate lyase
GXN76_01035	COG2884	Cell division ATP-binding protein ftsE
GXN76_01040	COG2177	Part of the ABC transporter FtsEX involved in
GXN76_01050	COG0793	Belongs to the peptidase S41A family
GXN76_01050	COG3409	Peptidoglycan-binding domain 1 protein
GXN76_01055	COG0556	nucleotide-excision repair
GXN76_01060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GXN76_01070	COG1213	nucleotidyl transferase
GXN76_01070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GXN76_01075	COG1196	nuclear chromosome segregation
GXN76_01075	COG0739	heme binding
GXN76_01075	COG0741	lytic transglycosylase activity
GXN76_01080	COG1950	PFAM Membrane protein of
GXN76_01085	COG3842	ATPase activity
GXN76_01090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GXN76_01100	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GXN76_01105	COG0546	phosphoglycolate phosphatase activity
GXN76_01110	COG0110	maltose O-acetyltransferase activity
GXN76_01130	COG0351	phosphomethylpyrimidine kinase
GXN76_01135	COG0167	dihydroorotate dehydrogenase activity
GXN76_01140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GXN76_01145	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GXN76_01150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GXN76_01155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GXN76_01160	COG0131	Imidazoleglycerol-phosphate dehydratase
GXN76_01165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GXN76_01170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GXN76_01175	COG0107	imidazoleglycerol-phosphate synthase activity
GXN76_01180	COG0140	phosphoribosyl-ATP diphosphatase activity
GXN76_01180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GXN76_01185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GXN76_01190	COG0457	Tetratricopeptide repeat
GXN76_01195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GXN76_01200	COG0517	IMP dehydrogenase activity
GXN76_01205	COG1051	belongs to the nudix hydrolase family
GXN76_01210	COG1940	carbohydrate kinase activity
GXN76_01215	COG1660	Displays ATPase and GTPase activities
GXN76_01220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GXN76_01225	COG1481	regulation of sporulation
GXN76_01230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GXN76_01245	COG0740	serine-type endopeptidase activity
GXN76_01255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GXN76_01275	COG0149	triose-phosphate isomerase activity
GXN76_01285	COG0148	phosphopyruvate hydratase activity
GXN76_01290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GXN76_01310	COG1647	Serine aminopeptidase, S33
GXN76_01315	COG0557	exoribonuclease II activity
GXN76_01320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GXN76_01335	COG1271	oxidase subunit
GXN76_01340	COG1294	oxidase, subunit
GXN76_01345	COG4988	ABC transporter
GXN76_01350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GXN76_01360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GXN76_01365	COG3711	transcriptional antiterminator
GXN76_01365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GXN76_01370	COG1447	Phosphotransferase system cellobiose-specific component IIA
GXN76_01375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GXN76_01395	COG3964	amidohydrolase
GXN76_01440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GXN76_01445	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_01450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GXN76_01455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GXN76_01465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GXN76_01475	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_01495	COG2226	methyltransferase
GXN76_01500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GXN76_01505	COG0400	carboxylic ester hydrolase activity
GXN76_01510	COG0346	lactoylglutathione lyase activity
GXN76_01515	COG2259	Doxx family
GXN76_01520	COG1733	regulation of RNA biosynthetic process
GXN76_01525	COG1609	Transcriptional regulator
GXN76_01540	COG1621	beta-fructofuranosidase activity
GXN76_01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXN76_01570	COG2032	superoxide dismutase activity
GXN76_01575	COG0288	reversible hydration of carbon dioxide
GXN76_01590	COG1131	(ABC) transporter
GXN76_01600	COG4585	Histidine kinase
GXN76_01605	COG2197	response regulator
GXN76_01610	COG2707	UPF0756 membrane protein
GXN76_01620	COG0586	Pfam SNARE associated Golgi protein
GXN76_01625	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_01630	COG4605	iron ion homeostasis
GXN76_01635	COG4604	ABC transporter, ATP-binding protein
GXN76_01640	COG4607	ABC-type enterochelin transport system periplasmic component
GXN76_01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GXN76_01715	COG3973	AAA domain
GXN76_01720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GXN76_01725	COG1309	transcriptional regulator
GXN76_01740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GXN76_01750	COG1803	Methylglyoxal synthase
GXN76_01750	COG1597	lipid kinase activity
GXN76_01755	COG0300	oxidoreductase activity
GXN76_01780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GXN76_01790	COG2323	membrane
GXN76_01820	COG1473	amidohydrolase
GXN76_01825	COG1473	amidohydrolase
GXN76_01830	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GXN76_01840	COG2190	(PTS) system
GXN76_01845	COG2814	Major facilitator Superfamily
GXN76_01850	COG0646	methionine synthase
GXN76_01850	COG1410	methionine synthase
GXN76_01855	COG0646	methionine synthase
GXN76_01855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GXN76_01870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GXN76_01885	COG1733	regulation of RNA biosynthetic process
GXN76_01890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GXN76_01910	COG1376	ErfK ybiS ycfS ynhG family protein
GXN76_01925	COG0737	Belongs to the 5'-nucleotidase family
GXN76_01930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GXN76_01950	COG4106	trans-aconitate 2-methyltransferase activity
GXN76_01955	COG1234	tRNA 3'-trailer cleavage
GXN76_01960	COG0745	RESPONSE REGULATOR receiver
GXN76_01965	COG2205	protein histidine kinase activity
GXN76_01990	COG0655	NAD(P)H dehydrogenase (quinone) activity
GXN76_02015	COG3764	Sortase (surface protein transpeptidase)
GXN76_02055	COG1196	nuclear chromosome segregation
GXN76_02055	COG0739	heme binding
GXN76_02055	COG0741	lytic transglycosylase activity
GXN76_02145	COG1250	3-hydroxyacyl-CoA dehydrogenase
GXN76_02145	COG1024	Enoyl-CoA hydratase
GXN76_02150	COG0183	Belongs to the thiolase family
GXN76_02155	COG1960	acyl-CoA dehydrogenase activity
GXN76_02170	COG4221	oxidoreductase activity
GXN76_02190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GXN76_02195	COG0154	amidase activity
GXN76_02200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GXN76_02220	COG1597	lipid kinase activity
GXN76_02235	COG4122	O-methyltransferase activity
GXN76_02240	COG0488	(ABC) transporter
GXN76_02245	COG4895	conserved protein (DUF2196)
GXN76_02255	COG0494	nUDIX hydrolase
GXN76_02265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_02270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_02275	COG1525	nuclease
GXN76_02280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GXN76_02295	COG3584	3D domain protein
GXN76_02300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GXN76_02315	COG0668	transmembrane transport
GXN76_02330	COG2720	vancomycin resistance protein
GXN76_02340	COG0456	acetyltransferase
GXN76_02345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GXN76_02355	COG0681	Belongs to the peptidase S26 family
GXN76_02360	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GXN76_02365	COG1132	(ABC) transporter
GXN76_02385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GXN76_02400	COG3336	cytochrome c oxidase
GXN76_02405	COG0730	response to heat
GXN76_02410	COG1959	2 iron, 2 sulfur cluster binding
GXN76_02415	COG0109	protoheme IX farnesyltransferase activity
GXN76_02425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GXN76_02435	COG3336	cytochrome c oxidase
GXN76_02440	COG2346	COG2346, Truncated hemoglobins
GXN76_02445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GXN76_02460	COG1027	Aspartate ammonia-lyase
GXN76_02495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GXN76_02505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GXN76_02510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GXN76_02515	COG0735	belongs to the Fur family
GXN76_02540	COG0745	RESPONSE REGULATOR receiver
GXN76_02545	COG5002	protein histidine kinase activity
GXN76_02545	COG3850	Histidine kinase
GXN76_02570	COG1301	dicarboxylic acid transport
GXN76_02575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GXN76_02580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GXN76_02585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GXN76_02590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GXN76_02595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GXN76_02600	COG0047	phosphoribosylformylglycinamidine synthase activity
GXN76_02605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GXN76_02610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GXN76_02615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GXN76_02620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GXN76_02625	COG0138	bifunctional purine biosynthesis protein purh
GXN76_02635	COG0151	Belongs to the GarS family
GXN76_02640	COG1215	transferase activity, transferring glycosyl groups
GXN76_02650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GXN76_02650	COG1213	nucleotidyl transferase
GXN76_02655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GXN76_02720	COG1470	cell adhesion involved in biofilm formation
GXN76_02725	COG4496	protein, YerC YecD
GXN76_02730	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GXN76_02740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GXN76_02745	COG0456	acetyltransferase
GXN76_02755	COG0564	pseudouridine synthase activity
GXN76_02775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_02780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_02785	COG3949	Membrane
GXN76_02790	COG0778	Nitroreductase
GXN76_02795	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GXN76_02810	COG1253	flavin adenine dinucleotide binding
GXN76_02825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GXN76_02830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_02835	COG1120	ATPase activity
GXN76_02840	COG2096	Adenosyltransferase
GXN76_02845	COG1393	Belongs to the ArsC family
GXN76_02850	COG2135	peptidase activity
GXN76_02855	COG4085	toxin activity
GXN76_02855	COG0737	Belongs to the 5'-nucleotidase family
GXN76_02855	COG1525	nuclease
GXN76_02860	COG0450	alkyl hydroperoxide reductase
GXN76_02865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GXN76_02870	COG0509	glycine decarboxylation via glycine cleavage system
GXN76_02880	COG0572	uridine kinase
GXN76_02885	COG4948	Mandelate Racemase Muconate Lactonizing
GXN76_02895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GXN76_02900	COG1185	polyribonucleotide nucleotidyltransferase activity
GXN76_02905	COG2815	serine threonine protein kinase
GXN76_02905	COG0515	serine threonine protein kinase
GXN76_02910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GXN76_02915	COG1242	4 iron, 4 sulfur cluster binding
GXN76_02950	COG0824	Thioesterase
GXN76_02955	COG4840	Belongs to the UPF0435 family
GXN76_02960	COG1547	Domain of unknown function (DUF309)
GXN76_02965	COG0084	hydrolase, TatD family'
GXN76_02990	COG0604	alcohol dehydrogenase
GXN76_03000	COG2322	membrane
GXN76_03005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GXN76_03020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GXN76_03040	COG4549	nuclear export factor GLE1
GXN76_03045	COG1349	DNA-binding transcription factor activity
GXN76_03055	COG1999	signal sequence binding
GXN76_03060	COG3443	Belongs to the bacterial solute-binding protein 9 family
GXN76_03060	COG0803	Belongs to the bacterial solute-binding protein 9 family
GXN76_03080	COG0095	Lipoate-protein ligase
GXN76_03085	COG2211	Major facilitator Superfamily
GXN76_03095	COG0133	tryptophan synthase activity
GXN76_03100	COG4555	ABC transporter
GXN76_03120	COG1309	transcriptional regulator
GXN76_03135	COG1716	ATPase activity
GXN76_03135	COG1131	(ABC) transporter
GXN76_03135	COG0842	Transport permease protein
GXN76_03145	COG5583	Uncharacterized small protein (DUF2292)
GXN76_03155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GXN76_03160	COG1414	Transcriptional regulator
GXN76_03165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GXN76_03175	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GXN76_03195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GXN76_03200	COG1191	sigma factor activity
GXN76_03205	COG4447	cellulose binding
GXN76_03210	COG2002	toxin-antitoxin pair type II binding
GXN76_03220	COG1024	Enoyl-CoA hydratase
GXN76_03255	COG0300	oxidoreductase activity
GXN76_03290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GXN76_03300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GXN76_03305	COG0693	protein deglycase activity
GXN76_03310	COG0396	ATPase activity
GXN76_03315	COG0719	Fe-S assembly protein
GXN76_03320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GXN76_03325	COG0822	iron-sulfur transferase activity
GXN76_03330	COG0719	Fe-S assembly protein
GXN76_03335	COG2808	Putative FMN-binding domain
GXN76_03350	COG1131	(ABC) transporter
GXN76_03355	COG0745	RESPONSE REGULATOR receiver
GXN76_03360	COG2205	protein histidine kinase activity
GXN76_03380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GXN76_03385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GXN76_03390	COG0179	Fumarylacetoacetate (FAA) hydrolase
GXN76_03400	COG1473	amidohydrolase
GXN76_03405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GXN76_03410	COG2171	N-acyltransferase activity
GXN76_03415	COG0512	Glutamine amidotransferase of anthranilate synthase
GXN76_03415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GXN76_03430	COG1131	(ABC) transporter
GXN76_03435	COG2205	protein histidine kinase activity
GXN76_03440	COG0745	RESPONSE REGULATOR receiver
GXN76_03470	COG0679	Auxin Efflux Carrier
GXN76_03480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GXN76_03490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GXN76_03495	COG2224	Isocitrate lyase
GXN76_03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GXN76_03520	COG1122	ATPase activity
GXN76_03525	COG1122	ATPase activity
GXN76_03535	COG0789	Transcriptional regulator
GXN76_03540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GXN76_03545	COG1733	regulation of RNA biosynthetic process
GXN76_03550	COG0789	Transcriptional regulator
GXN76_03555	COG2814	Major facilitator Superfamily
GXN76_03575	COG3708	Transcriptional regulator
GXN76_03575	COG2207	Transcriptional regulator
GXN76_03580	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_03590	COG0697	spore germination
GXN76_03620	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GXN76_03635	COG0456	acetyltransferase
GXN76_03640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXN76_03650	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GXN76_03660	COG1492	cobalamin metabolic process
GXN76_03670	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GXN76_03675	COG1620	l-lactate permease
GXN76_03695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GXN76_03705	COG1801	Protein of unknown function DUF72
GXN76_03720	COG0730	response to heat
GXN76_03725	COG0737	Belongs to the 5'-nucleotidase family
GXN76_03730	COG4708	membrane
GXN76_03745	COG3377	Domain of unknown function (DUF1805)
GXN76_03765	COG0564	pseudouridine synthase activity
GXN76_03775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GXN76_03780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GXN76_03800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GXN76_03810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GXN76_03815	COG1017	nitric oxide dioxygenase activity
GXN76_03815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GXN76_03845	COG0483	inositol monophosphate 1-phosphatase activity
GXN76_03870	COG1966	Carbon starvation protein
GXN76_03880	COG0003	Pfam Anion-transporting ATPase
GXN76_03890	COG2309	aminopeptidase activity
GXN76_03895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GXN76_03900	COG3424	synthase
GXN76_03905	COG1755	Isoprenylcysteine carboxyl methyltransferase
GXN76_03915	COG2234	aminopeptidase activity
GXN76_03925	COG0444	Belongs to the ABC transporter superfamily
GXN76_03930	COG4608	Belongs to the ABC transporter superfamily
GXN76_03935	COG0747	negative chemotaxis
GXN76_03950	COG0471	metal ion transport
GXN76_03955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GXN76_03970	COG0733	neurotransmitter:sodium symporter activity
GXN76_03975	COG0733	neurotransmitter:sodium symporter activity
GXN76_03985	COG0739	heme binding
GXN76_03995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GXN76_04005	COG4470	Protein conserved in bacteria
GXN76_04025	COG3594	Acyltransferase
GXN76_04040	COG2445	Protein of unknown function DUF86
GXN76_04055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GXN76_04060	COG0647	UMP catabolic process
GXN76_04070	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_04080	COG2203	Gaf domain
GXN76_04080	COG4585	Histidine kinase
GXN76_04085	COG2197	response regulator
GXN76_04090	COG1272	protein, Hemolysin III
GXN76_04135	COG3246	L-lysine catabolic process to acetate
GXN76_04140	COG1510	regulation of RNA biosynthetic process
GXN76_04145	COG1125	glycine betaine transport
GXN76_04145	COG0517	IMP dehydrogenase activity
GXN76_04150	COG1174	glycine betaine transport
GXN76_04155	COG1732	Glycine betaine
GXN76_04160	COG1174	glycine betaine transport
GXN76_04170	COG2076	Multidrug Resistance protein
GXN76_04200	COG1489	DNA binding
GXN76_04205	COG0488	(ABC) transporter
GXN76_04210	COG0247	lactate metabolic process
GXN76_04215	COG0277	FAD linked oxidase domain protein
GXN76_04220	COG1297	OPT oligopeptide transporter protein
GXN76_04235	COG4166	transmembrane transport
GXN76_04240	COG0601	transmembrane transport
GXN76_04245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GXN76_04250	COG0444	Belongs to the ABC transporter superfamily
GXN76_04255	COG4608	Belongs to the ABC transporter superfamily
GXN76_04260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GXN76_04265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GXN76_04270	COG0626	cystathionine gamma-synthase activity
GXN76_04275	COG4837	Protein of unknown function (DUF1462)
GXN76_04285	COG3764	Sortase (surface protein transpeptidase)
GXN76_04315	COG1960	acyl-CoA dehydrogenase activity
GXN76_04345	COG4844	belongs to the
GXN76_04350	COG2309	aminopeptidase activity
GXN76_04360	COG0316	Belongs to the HesB IscA family
GXN76_04380	COG0492	ferredoxin-NADP+ reductase activity
GXN76_04385	COG1252	NADH dehydrogenase
GXN76_04390	COG0656	L-ascorbic acid biosynthetic process
GXN76_04415	COG1247	-acetyltransferase
GXN76_04420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GXN76_04435	COG1115	amino acid carrier protein
GXN76_04475	COG0384	phenazine biosynthesis protein PhzF
GXN76_04490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GXN76_04495	COG2169	Transcriptional regulator
GXN76_04500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GXN76_04505	COG0753	catalase activity
GXN76_04515	COG1331	Highly conserved protein containing a thioredoxin domain
GXN76_04525	COG1764	response to oxidative stress
GXN76_04535	COG0668	transmembrane transport
GXN76_04540	COG2252	PERMEase
GXN76_04545	COG0477	Major facilitator Superfamily
GXN76_04550	COG0488	(ABC) transporter
GXN76_04550	COG0488	(ABC) transporter
GXN76_04560	COG2814	Major facilitator Superfamily
GXN76_04565	COG2188	Transcriptional regulator
GXN76_04580	COG1609	Transcriptional regulator
GXN76_04585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GXN76_04590	COG1869	D-ribose catabolic process
GXN76_04600	COG1172	Belongs to the binding-protein-dependent transport system permease family
GXN76_04605	COG1879	ABC-type sugar transport system periplasmic component
GXN76_04615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GXN76_04620	COG2814	Major facilitator Superfamily
GXN76_04625	COG2391	methyltransferase activity
GXN76_04630	COG0492	ferredoxin-NADP+ reductase activity
GXN76_04635	COG1595	DNA-templated transcription, initiation
GXN76_04650	COG1063	alcohol dehydrogenase
GXN76_04655	COG2190	(PTS) system
GXN76_04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXN76_04655	COG1263	PTS System
GXN76_04660	COG0366	Alpha amylase catalytic
GXN76_04665	COG2188	Transcriptional regulator
GXN76_04675	COG1575	Belongs to the MenA family. Type 1 subfamily
GXN76_04680	COG1169	isochorismate synthase
GXN76_04690	COG0596	Alpha beta hydrolase
GXN76_04695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GXN76_04700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GXN76_04710	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_04730	COG2362	D-Aminopeptidase
GXN76_04735	COG2130	NADP-dependent
GXN76_04765	COG0095	Lipoate-protein ligase
GXN76_04770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GXN76_04775	COG0456	acetyltransferase
GXN76_04785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GXN76_04820	COG1072	(Pantothenic acid kinase))
GXN76_04825	COG1309	transcriptional regulator
GXN76_04830	COG3396	Phenylacetate-CoA oxygenase
GXN76_04845	COG2151	metal-sulfur cluster biosynthetic enzyme
GXN76_04850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GXN76_04860	COG1250	3-hydroxyacyl-CoA dehydrogenase
GXN76_04865	COG1250	3-hydroxyacyl-CoA dehydrogenase
GXN76_04870	COG0183	Belongs to the thiolase family
GXN76_04875	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_04905	COG1309	transcriptional regulator
GXN76_04915	COG1329	Transcriptional regulator
GXN76_04925	COG1573	uracil-dna glycosylase
GXN76_04940	COG0328	RNA-DNA hybrid ribonuclease activity
GXN76_04950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GXN76_04955	COG1132	(ABC) transporter
GXN76_04960	COG1132	(ABC) transporter
GXN76_04970	COG1307	EDD domain protein, DegV family
GXN76_04975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GXN76_04990	COG2766	serine protein kinase
GXN76_05010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GXN76_05025	COG0475	glutathione-regulated potassium exporter activity
GXN76_05030	COG0490	domain, Protein
GXN76_05055	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GXN76_05070	COG1115	amino acid carrier protein
GXN76_05075	COG0681	Belongs to the peptidase S26 family
GXN76_05080	COG0745	RESPONSE REGULATOR receiver
GXN76_05085	COG5002	protein histidine kinase activity
GXN76_05090	COG1136	(ABC) transporter
GXN76_05095	COG0577	efflux transmembrane transporter activity
GXN76_05100	COG1131	(ABC) transporter
GXN76_05115	COG1304	FMN binding
GXN76_05130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GXN76_05135	COG2719	SpoVR family
GXN76_05140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GXN76_05160	COG2719	SpoVR family
GXN76_05175	COG0189	ligase activity
GXN76_05180	COG0189	ligase activity
GXN76_05185	COG0189	ligase activity
GXN76_05190	COG0189	ligase activity
GXN76_05210	COG4109	DRTGG domain
GXN76_05235	COG0587	DNA-directed DNA polymerase activity
GXN76_05240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GXN76_05250	COG0175	sulfate reduction
GXN76_05255	COG0306	phosphate transporter
GXN76_05260	COG2046	Belongs to the sulfate adenylyltransferase family
GXN76_05265	COG0529	Catalyzes the synthesis of activated sulfate
GXN76_05270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GXN76_05285	COG3428	Bacterial PH domain
GXN76_05290	COG3402	PFAM membrane-flanked domain
GXN76_05295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GXN76_05295	COG1648	precorrin-2 dehydrogenase activity
GXN76_05310	COG0281	malic enzyme
GXN76_05315	COG2186	Transcriptional regulator
GXN76_05320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GXN76_05325	COG0825	malonyl-CoA metabolic process
GXN76_05330	COG0205	6-phosphofructokinase activity
GXN76_05340	COG0824	Thioesterase
GXN76_05345	COG3030	protein affecting phage T7 exclusion by the F plasmid
GXN76_05350	COG0372	Belongs to the citrate synthase family
GXN76_05355	COG0538	isocitrate dehydrogenase activity
GXN76_05360	COG0039	L-malate dehydrogenase activity
GXN76_05365	COG0745	RESPONSE REGULATOR receiver
GXN76_05370	COG5002	protein histidine kinase activity
GXN76_05375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GXN76_05380	COG0573	inorganic phosphate transmembrane transporter activity
GXN76_05385	COG0581	inorganic phosphate transmembrane transporter activity
GXN76_05390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GXN76_05395	COG0704	Plays a role in the regulation of phosphate uptake
GXN76_05415	COG2011	ABC-type metal ion transport system permease component
GXN76_05430	COG0371	Dehydrogenase
GXN76_05440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GXN76_05440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GXN76_05445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GXN76_05450	COG0237	dephospho-CoA kinase activity
GXN76_05455	COG0741	lytic transglycosylase activity
GXN76_05455	COG0739	heme binding
GXN76_05455	COG1196	nuclear chromosome segregation
GXN76_05460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GXN76_05465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GXN76_05475	COG1484	DNA-dependent DNA replication
GXN76_05495	COG1396	sequence-specific DNA binding
GXN76_05515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GXN76_05530	COG1988	membrane-bound metal-dependent
GXN76_05540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GXN76_05545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GXN76_05550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GXN76_05555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GXN76_05565	COG1396	sequence-specific DNA binding
GXN76_05570	COG1846	Transcriptional regulator
GXN76_05585	COG0129	dihydroxy-acid dehydratase activity
GXN76_05590	COG0028	Belongs to the TPP enzyme family
GXN76_05595	COG0440	acetolactate synthase activity
GXN76_05600	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GXN76_05605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GXN76_05610	COG0473	3-isopropylmalate dehydrogenase activity
GXN76_05620	COG0693	protein deglycase activity
GXN76_05625	COG0628	permease
GXN76_05630	COG0352	thiamine-phosphate diphosphorylase activity
GXN76_05635	COG0351	phosphomethylpyrimidine kinase
GXN76_05650	COG1363	Peptidase, m42
GXN76_05660	COG0569	domain protein
GXN76_05665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GXN76_05670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GXN76_05675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GXN76_05675	COG0072	phenylalanine-tRNA ligase activity
GXN76_05680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GXN76_05685	COG1286	toxin biosynthetic process
GXN76_05690	COG1796	DNA polymerase
GXN76_05690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GXN76_05705	COG1193	negative regulation of DNA recombination
GXN76_05725	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GXN76_05725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GXN76_05735	COG2081	HI0933 family
GXN76_05745	COG0697	spore germination
GXN76_05750	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_05755	COG1309	transcriptional regulator
GXN76_05760	COG2086	electron transfer activity
GXN76_05765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GXN76_05770	COG3118	belongs to the thioredoxin family
GXN76_05785	COG0322	excinuclease ABC activity
GXN76_05795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GXN76_05810	COG4166	transmembrane transport
GXN76_05815	COG0601	transmembrane transport
GXN76_05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GXN76_05825	COG0444	Belongs to the ABC transporter superfamily
GXN76_05830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GXN76_05835	COG2009	succinate dehydrogenase
GXN76_05840	COG1053	succinate dehydrogenase
GXN76_05845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GXN76_05855	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GXN76_05860	COG4086	secreted protein
GXN76_05865	COG0768	penicillin binding
GXN76_05890	COG2340	Cysteine-rich secretory protein family
GXN76_05900	COG2323	membrane
GXN76_05910	COG2197	response regulator
GXN76_05920	COG1846	Transcriptional regulator
GXN76_05935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GXN76_05940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GXN76_05945	COG0622	Phosphoesterase
GXN76_05955	COG0544	peptidyl-prolyl cis-trans isomerase activity
GXN76_05960	COG0740	serine-type endopeptidase activity
GXN76_05965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GXN76_05970	COG2348	transferase activity, transferring amino-acyl groups
GXN76_05980	COG0470	DNA polymerase III
GXN76_05980	COG1067	ATP-dependent peptidase activity
GXN76_05990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GXN76_05995	COG1181	Belongs to the D-alanine--D-alanine ligase family
GXN76_06000	COG0024	Methionine aminopeptidase
GXN76_06010	COG4585	Histidine kinase
GXN76_06020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GXN76_06025	COG1116	anion transmembrane transporter activity
GXN76_06030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GXN76_06035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GXN76_06040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GXN76_06045	COG0181	hydroxymethylbilane synthase activity
GXN76_06055	COG0113	porphobilinogen synthase activity
GXN76_06065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GXN76_06070	COG1388	LysM domain
GXN76_06085	COG0525	valine-tRNA ligase activity
GXN76_06090	COG0285	dihydrofolate synthase activity
GXN76_06095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GXN76_06100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GXN76_06115	COG4473	ABC transporter
GXN76_06120	COG1131	(ABC) transporter
GXN76_06125	COG1657	PFAM Prenyltransferase squalene oxidase
GXN76_06140	COG0424	maF-like protein
GXN76_06145	COG2003	Belongs to the UPF0758 family
GXN76_06150	COG1077	Cell shape determining protein MreB Mrl
GXN76_06155	COG1792	Involved in formation and maintenance of cell shape
GXN76_06165	COG0850	regulation of cytokinetic process
GXN76_06170	COG2894	cell division
GXN76_06175	COG0400	carboxylic ester hydrolase activity
GXN76_06180	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_06190	COG1994	Peptidase M50
GXN76_06195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GXN76_06205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GXN76_06215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GXN76_06225	COG1136	(ABC) transporter
GXN76_06225	COG0577	efflux transmembrane transporter activity
GXN76_06235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GXN76_06240	COG4492	Belongs to the UPF0735 family
GXN76_06245	COG0460	homoserine dehydrogenase
GXN76_06250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GXN76_06255	COG0083	homoserine kinase activity
GXN76_06260	COG0077	Prephenate dehydratase
GXN76_06270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GXN76_06275	COG1131	(ABC) transporter
GXN76_06280	COG2755	lipolytic protein G-D-S-L family
GXN76_06285	COG1388	LysM domain
GXN76_06295	COG0217	transcriptional regulatory protein
GXN76_06300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GXN76_06305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GXN76_06310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GXN76_06310	COG1321	iron dependent repressor
GXN76_06315	COG1121	(ABC) transporter
GXN76_06320	COG0803	Belongs to the bacterial solute-binding protein 9 family
GXN76_06325	COG0745	RESPONSE REGULATOR receiver
GXN76_06330	COG5002	protein histidine kinase activity
GXN76_06355	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GXN76_06360	COG0632	four-way junction helicase activity
GXN76_06365	COG2255	four-way junction helicase activity
GXN76_06375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GXN76_06380	COG0343	queuine tRNA-ribosyltransferase activity
GXN76_06385	COG1862	Preprotein translocase
GXN76_06390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GXN76_06415	COG0582	viral genome integration into host DNA
GXN76_06435	COG2323	membrane
GXN76_06440	COG2244	polysaccharide biosynthetic process
GXN76_06455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GXN76_06460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GXN76_06460	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GXN76_06465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GXN76_06480	COG0697	spore germination
GXN76_06490	COG1078	dGTPase activity
GXN76_06495	COG1763	Mo-molybdopterin cofactor biosynthetic process
GXN76_06500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GXN76_06505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GXN76_06545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GXN76_06565	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_06570	COG1454	alcohol dehydrogenase
GXN76_06585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GXN76_06590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GXN76_06595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GXN76_06600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GXN76_06610	COG0583	DNA-binding transcription factor activity
GXN76_06615	COG0655	NAD(P)H dehydrogenase (quinone) activity
GXN76_06630	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_06650	COG0277	FAD linked oxidase domain protein
GXN76_06665	COG0095	Lipoate-protein ligase
GXN76_06680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GXN76_06720	COG0514	ATP-dependent DNA helicase (RecQ)
GXN76_06725	COG2986	histidine ammonia-lyase
GXN76_06735	COG1321	iron dependent repressor
GXN76_06740	COG1752	Esterase of the alpha-beta hydrolase superfamily
GXN76_06750	COG3872	metal-dependent enzyme
GXN76_06755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GXN76_06760	COG0006	proline dipeptidase activity
GXN76_06765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GXN76_06775	COG0531	amino acid
GXN76_06780	COG2707	UPF0756 membrane protein
GXN76_06790	COG1809	phosphosulfolactate synthase activity
GXN76_06795	COG2814	Major facilitator Superfamily
GXN76_06805	COG3854	ATPases associated with a variety of cellular activities
GXN76_06845	COG0511	ligase activity, forming carbon-carbon bonds
GXN76_06850	COG0439	Biotin carboxylase
GXN76_06855	COG1302	Protein conserved in bacteria
GXN76_06860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GXN76_06865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GXN76_06885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GXN76_06890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GXN76_06900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GXN76_06905	COG1438	arginine binding
GXN76_06910	COG0497	DNA recombination
GXN76_06915	COG0750	zinc metalloprotease
GXN76_06935	COG1929	Belongs to the glycerate kinase type-1 family
GXN76_06940	COG0006	proline dipeptidase activity
GXN76_06950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GXN76_06960	COG3829	transcription factor binding
GXN76_06960	COG3290	protein histidine kinase activity
GXN76_06970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GXN76_06975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GXN76_06980	COG0022	dehydrogenase e1 component
GXN76_06985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXN76_06990	COG1802	Transcriptional regulator
GXN76_06995	COG0697	spore germination
GXN76_07000	COG2323	membrane
GXN76_07015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_07015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_07020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_07020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_07025	COG0346	lactoylglutathione lyase activity
GXN76_07030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GXN76_07035	COG2195	Cleaves the N-terminal amino acid of tripeptides
GXN76_07060	COG1379	DNA repair
GXN76_07065	COG1300	Membrane
GXN76_07070	COG0735	belongs to the Fur family
GXN76_07075	COG0686	Belongs to the AlaDH PNT family
GXN76_07085	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GXN76_07110	COG1686	Belongs to the peptidase S11 family
GXN76_07145	COG0019	diaminopimelate decarboxylase activity
GXN76_07150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_07155	COG0739	heme binding
GXN76_07160	COG1612	heme a metabolic process
GXN76_07170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GXN76_07170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GXN76_07175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GXN76_07180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GXN76_07185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GXN76_07195	COG1131	(ABC) transporter
GXN76_07200	COG2205	protein histidine kinase activity
GXN76_07205	COG0745	RESPONSE REGULATOR receiver
GXN76_07215	COG3874	Sporulation protein YtfJ
GXN76_07220	COG1686	Belongs to the peptidase S11 family
GXN76_07225	COG2715	membrane protein required for spore maturation
GXN76_07230	COG0700	Nucleoside recognition
GXN76_07235	COG1187	pseudouridine synthase activity
GXN76_07240	COG1333	cytochrome c biogenesis protein
GXN76_07245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GXN76_07250	COG0745	RESPONSE REGULATOR receiver
GXN76_07255	COG5002	protein histidine kinase activity
GXN76_07260	COG4221	oxidoreductase activity
GXN76_07270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GXN76_07275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GXN76_07280	COG0210	DNA helicase
GXN76_07295	COG1141	Ferredoxin
GXN76_07300	COG1266	CAAX protease self-immunity
GXN76_07320	COG4862	establishment of competence for transformation
GXN76_07325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GXN76_07330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GXN76_07335	COG0492	ferredoxin-NADP+ reductase activity
GXN76_07340	COG0252	asparaginase activity
GXN76_07345	COG2959	enzyme of heme biosynthesis
GXN76_07355	COG0204	Acyl-transferase
GXN76_07360	COG0539	negative regulation of cytoplasmic translation
GXN76_07380	COG1160	GTP binding
GXN76_07385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GXN76_07390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GXN76_07410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GXN76_07415	COG0776	regulation of translation
GXN76_07420	COG0302	gtp cyclohydrolase
GXN76_07440	COG0142	geranyltranstransferase activity
GXN76_07450	COG0142	geranyltranstransferase activity
GXN76_07455	COG0105	UTP biosynthetic process
GXN76_07475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GXN76_07480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GXN76_07485	COG4401	Chorismate mutase type I
GXN76_07495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GXN76_07500	COG0134	indole-3-glycerol-phosphate synthase activity
GXN76_07505	COG0135	phosphoribosylanthranilate isomerase activity
GXN76_07510	COG0133	tryptophan synthase activity
GXN76_07520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXN76_07525	COG0287	Prephenate dehydrogenase
GXN76_07530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GXN76_07545	COG5582	Belongs to the UPF0302 family
GXN76_07580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GXN76_07605	COG1694	Mazg nucleotide pyrophosphohydrolase
GXN76_07610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GXN76_07615	COG0590	tRNA wobble adenosine to inosine editing
GXN76_07620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXN76_07625	COG0531	amino acid
GXN76_07630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GXN76_07635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GXN76_07650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXN76_07670	COG1803	Methylglyoxal synthase
GXN76_07675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GXN76_07680	COG0438	transferase activity, transferring glycosyl groups
GXN76_07685	COG0617	tRNA 3'-terminal CCA addition
GXN76_07700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GXN76_07705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GXN76_07720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GXN76_07740	COG3285	dna ligase
GXN76_07740	COG1793	dna ligase
GXN76_07745	COG0402	S-adenosylhomocysteine deaminase activity
GXN76_07765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXN76_07770	COG0436	Aminotransferase
GXN76_07775	COG1301	dicarboxylic acid transport
GXN76_07785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GXN76_07810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GXN76_07815	COG1254	Belongs to the acylphosphatase family
GXN76_07820	COG4974	Belongs to the 'phage' integrase family
GXN76_07835	COG0242	peptide deformylase activity
GXN76_07840	COG2205	protein histidine kinase activity
GXN76_07845	COG0745	RESPONSE REGULATOR receiver
GXN76_07865	COG2304	oxidoreductase activity
GXN76_07890	COG2226	methyltransferase
GXN76_07905	COG0494	nUDIX hydrolase
GXN76_07910	COG2378	regulation of single-species biofilm formation
GXN76_07920	COG0666	response to abiotic stimulus
GXN76_07940	COG0583	DNA-binding transcription factor activity
GXN76_07945	COG1785	Belongs to the alkaline phosphatase family
GXN76_07985	COG4948	Mandelate Racemase Muconate Lactonizing
GXN76_08005	COG0604	alcohol dehydrogenase
GXN76_08035	COG0714	Associated with various cellular activities
GXN76_08055	COG1363	Peptidase, m42
GXN76_08060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GXN76_08065	COG4224	UPF0291 protein
GXN76_08075	COG0529	Catalyzes the synthesis of activated sulfate
GXN76_08080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GXN76_08095	COG4974	Belongs to the 'phage' integrase family
GXN76_08140	COG1216	Glycosyl transferase, family 2
GXN76_08150	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GXN76_08165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GXN76_08170	COG0861	Integral membrane protein TerC family
GXN76_08175	COG0456	acetyltransferase
GXN76_08175	COG1214	PFAM Peptidase M22, glycoprotease
GXN76_08180	COG0860	N-Acetylmuramoyl-L-alanine amidase
GXN76_08190	COG1694	Mazg nucleotide pyrophosphohydrolase
GXN76_08200	COG1122	ATPase activity
GXN76_08205	COG1960	acyl-CoA dehydrogenase activity
GXN76_08220	COG0500	methyltransferase
GXN76_08225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GXN76_08275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GXN76_08295	COG1522	sequence-specific DNA binding
GXN76_08300	COG1131	(ABC) transporter
GXN76_08305	COG0438	transferase activity, transferring glycosyl groups
GXN76_08310	COG3935	DnaD domain protein
GXN76_08315	COG0017	Asparaginyl-tRNA synthetase
GXN76_08330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GXN76_08345	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_08355	COG3321	synthase
GXN76_08360	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_08375	COG2124	cytochrome p450
GXN76_08385	COG0165	Argininosuccinate lyase
GXN76_08415	COG4555	ABC transporter
GXN76_08420	COG2197	response regulator
GXN76_08430	COG0174	glutamine synthetase
GXN76_08435	COG2839	Protein conserved in bacteria
GXN76_08440	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GXN76_08450	COG0464	growth
GXN76_08455	COG1923	regulation of RNA biosynthetic process
GXN76_08460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GXN76_08470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GXN76_08475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GXN76_08490	COG4550	Control of competence regulator ComK, YlbF/YmcA
GXN76_08495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GXN76_08500	COG0156	8-amino-7-oxononanoate synthase activity
GXN76_08505	COG1063	alcohol dehydrogenase
GXN76_08520	COG1234	tRNA 3'-trailer cleavage
GXN76_08525	COG1013	pyruvate-flavodoxin oxidoreductase activity
GXN76_08530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GXN76_08530	COG0674	pyruvate-flavodoxin oxidoreductase activity
GXN76_08540	COG2359	stage V sporulation protein S
GXN76_08545	COG1692	metallophosphoesterase
GXN76_08580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GXN76_08585	COG2151	metal-sulfur cluster biosynthetic enzyme
GXN76_08595	COG1546	Belongs to the CinA family
GXN76_08595	COG1058	Belongs to the CinA family
GXN76_08600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GXN76_08605	COG1426	Protein conserved in bacteria
GXN76_08615	COG1426	Protein conserved in bacteria
GXN76_08630	COG0300	oxidoreductase activity
GXN76_08635	COG0612	Peptidase, M16
GXN76_08640	COG0612	Peptidase, M16
GXN76_08675	COG0740	serine-type endopeptidase activity
GXN76_08680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GXN76_08685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GXN76_08690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GXN76_08695	COG0527	aspartate kinase activity
GXN76_08700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GXN76_08705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GXN76_08710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GXN76_08725	COG0756	dUTP diphosphatase activity
GXN76_08730	COG0612	Peptidase, M16
GXN76_08735	COG0726	polysaccharide deacetylase
GXN76_08740	COG1185	polyribonucleotide nucleotidyltransferase activity
GXN76_08745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GXN76_08750	COG0196	riboflavin kinase activity
GXN76_08755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GXN76_08760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GXN76_08765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GXN76_08775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GXN76_08780	COG1358	cellular component organization or biogenesis
GXN76_08785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GXN76_08790	COG0195	Participates in both transcription termination and antitermination
GXN76_08795	COG0779	Required for maturation of 30S ribosomal subunits
GXN76_08800	COG2176	DNA-directed DNA polymerase activity
GXN76_08805	COG0442	prolyl-tRNA aminoacylation
GXN76_08810	COG0750	zinc metalloprotease
GXN76_08815	COG0750	zinc metalloprotease
GXN76_08820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GXN76_08825	COG4589	Belongs to the CDS family
GXN76_08835	COG0233	cytoplasmic translational termination
GXN76_08845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GXN76_08850	COG0052	Belongs to the universal ribosomal protein uS2 family
GXN76_08855	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GXN76_08860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GXN76_08865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GXN76_08870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GXN76_08880	COG0758	DNA mediated transformation
GXN76_08885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GXN76_08890	COG0045	succinate-CoA ligase (ADP-forming) activity
GXN76_08915	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GXN76_08930	COG2050	protein possibly involved in aromatic compounds catabolism
GXN76_08935	COG0183	Belongs to the thiolase family
GXN76_08945	COG2226	methyltransferase
GXN76_08960	COG5505	Protein of unknown function (DUF819)
GXN76_08985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GXN76_08990	COG1228	amidohydrolase
GXN76_08995	COG0010	Belongs to the arginase family
GXN76_09005	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GXN76_09015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GXN76_09020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GXN76_09025	COG0590	tRNA wobble adenosine to inosine editing
GXN76_09030	COG2233	PERMEase
GXN76_09035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_09050	COG0606	chelatase, subunit chli
GXN76_09065	COG2124	cytochrome p450
GXN76_09075	COG5285	phytanoyl-CoA dioxygenase
GXN76_09095	COG1509	lysine 2,3-aminomutase activity
GXN76_09115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GXN76_09125	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GXN76_09160	COG2610	gluconate transmembrane transporter activity
GXN76_09165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GXN76_09170	COG3395	kinase activity
GXN76_09175	COG1349	DNA-binding transcription factor activity
GXN76_09190	COG0792	nuclease activity
GXN76_09195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GXN76_09200	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GXN76_09205	COG0681	Belongs to the peptidase S26 family
GXN76_09210	COG0335	large ribosomal subunit rRNA binding
GXN76_09215	COG0336	Belongs to the RNA methyltransferase TrmD family
GXN76_09220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GXN76_09225	COG1837	Belongs to the UPF0109 family
GXN76_09230	COG0228	four-way junction DNA binding
GXN76_09235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GXN76_09240	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GXN76_09245	COG2851	Citrate transporter
GXN76_09250	COG2258	MOSC domain
GXN76_09255	COG0552	protein localization to endoplasmic reticulum
GXN76_09260	COG1196	nuclear chromosome segregation
GXN76_09265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GXN76_09270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GXN76_09275	COG0571	ribonuclease III activity
GXN76_09280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GXN76_09285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GXN76_09290	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_09295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GXN76_09305	COG0416	fatty acid biosynthetic process
GXN76_09315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GXN76_09325	COG3480	Lon protease (S16) C-terminal proteolytic domain
GXN76_09330	COG1752	Esterase of the alpha-beta hydrolase superfamily
GXN76_09335	COG3314	Sporulation integral membrane protein YlbJ
GXN76_09340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GXN76_09345	COG0742	ribosomal rna small subunit methyltransferase
GXN76_09360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GXN76_09365	COG1307	EDD domain protein, DegV family
GXN76_09370	COG1461	Dihydroxyacetone kinase
GXN76_09375	COG1302	Protein conserved in bacteria
GXN76_09380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GXN76_09390	COG1564	THIamine pyrophosphokinase
GXN76_09395	COG3859	Proton-coupled thiamine transporter YuaJ
GXN76_09400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GXN76_09405	COG1162	GTPase activity
GXN76_09410	COG0515	serine threonine protein kinase
GXN76_09410	COG2815	serine threonine protein kinase
GXN76_09415	COG0631	protein serine/threonine phosphatase activity
GXN76_09420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GXN76_09425	COG1937	Protein conserved in bacteria
GXN76_09445	COG0697	spore germination
GXN76_09455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GXN76_09455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GXN76_09465	COG0242	peptide deformylase activity
GXN76_09470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GXN76_09475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GXN76_09480	COG1758	RNA polymerase activity
GXN76_09485	COG0194	GDP metabolic process
GXN76_09495	COG1561	YicC-like family, N-terminal region
GXN76_09505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GXN76_09510	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GXN76_09515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GXN76_09520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GXN76_09525	COG1940	carbohydrate kinase activity
GXN76_09530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GXN76_09540	COG5564	TIM-barrel signal transduction protein
GXN76_09550	COG4145	pantothenate transmembrane transporter activity
GXN76_09560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GXN76_09565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GXN76_09570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GXN76_09580	COG0640	Transcriptional regulator
GXN76_09585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GXN76_09600	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GXN76_09600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GXN76_09615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GXN76_09620	COG1715	Restriction endonuclease
GXN76_09640	COG1136	(ABC) transporter
GXN76_09640	COG0577	efflux transmembrane transporter activity
GXN76_09655	COG0393	Putative heavy-metal-binding
GXN76_09675	COG1595	DNA-templated transcription, initiation
GXN76_09680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GXN76_09695	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GXN76_09700	COG1131	(ABC) transporter
GXN76_09715	COG2084	Dehydrogenase
GXN76_09720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GXN76_09725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GXN76_09735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GXN76_09745	COG0191	fructose-bisphosphate aldolase activity
GXN76_09750	COG1414	Transcriptional regulator
GXN76_09760	COG0028	Belongs to the TPP enzyme family
GXN76_09765	COG3395	kinase activity
GXN76_09770	COG3958	Transketolase
GXN76_09775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GXN76_09780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GXN76_09790	COG2508	Transcriptional regulator
GXN76_09800	COG3648	Uricase
GXN76_09800	COG3195	allantoin biosynthetic process
GXN76_09805	COG2351	hydroxyisourate hydrolase activity
GXN76_09810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GXN76_09820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GXN76_09830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GXN76_09835	COG0540	Belongs to the ATCase OTCase family
GXN76_09840	COG2233	PERMEase
GXN76_09845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GXN76_09850	COG0564	pseudouridine synthase activity
GXN76_09855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GXN76_09860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GXN76_09885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GXN76_09905	COG0762	integral membrane protein
GXN76_09910	COG1799	cell septum assembly
GXN76_09915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GXN76_09925	COG1873	PFAM PRC-barrel domain
GXN76_09930	COG1191	sigma factor activity
GXN76_09935	COG1191	sigma factor activity
GXN76_09945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GXN76_09950	COG0849	cell division
GXN76_09960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GXN76_09965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GXN76_09970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GXN76_09975	COG0772	Belongs to the SEDS family
GXN76_09980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GXN76_09985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GXN76_09990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GXN76_09995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GXN76_10000	COG0768	penicillin binding
GXN76_10005	COG0768	penicillin binding
GXN76_10015	COG0275	rRNA processing
GXN76_10020	COG2001	Belongs to the MraZ family
GXN76_10025	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GXN76_10030	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GXN76_10035	COG2814	Major facilitator Superfamily
GXN76_10040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GXN76_10045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GXN76_10050	COG1024	Enoyl-CoA hydratase
GXN76_10055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GXN76_10060	COG0511	ligase activity, forming carbon-carbon bonds
GXN76_10065	COG0439	Biotin carboxylase
GXN76_10070	COG0454	-acetyltransferase
GXN76_10105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GXN76_10120	COG0785	Cytochrome C biogenesis protein
GXN76_10125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GXN76_10140	COG0745	RESPONSE REGULATOR receiver
GXN76_10145	COG0745	RESPONSE REGULATOR receiver
GXN76_10155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GXN76_10185	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GXN76_10190	COG0584	glycerophosphoryl diester phosphodiesterase
GXN76_10200	COG0179	Fumarylacetoacetate (FAA) hydrolase
GXN76_10205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GXN76_10215	COG4493	Belongs to the UPF0637 family
GXN76_10220	COG1982	Orn Lys Arg decarboxylase major
GXN76_10225	COG0647	UMP catabolic process
GXN76_10235	COG3842	ATPase activity
GXN76_10265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GXN76_10305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GXN76_10310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GXN76_10335	COG1823	symporter activity
GXN76_10340	COG0733	neurotransmitter:sodium symporter activity
GXN76_10345	COG0653	protein targeting
GXN76_10350	COG3583	domain protein
GXN76_10350	COG3584	3D domain protein
GXN76_10355	COG2720	vancomycin resistance protein
GXN76_10360	COG3326	Membrane
GXN76_10365	COG1271	oxidase subunit
GXN76_10370	COG1294	oxidase, subunit
GXN76_10375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GXN76_10380	COG2155	Conserved Protein
GXN76_10385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GXN76_10405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GXN76_10410	COG2066	Belongs to the glutaminase family
GXN76_10435	COG1473	amidohydrolase
GXN76_10460	COG4537	Required for transformation and DNA binding
GXN76_10465	COG1459	type II secretion system
GXN76_10475	COG0577	efflux transmembrane transporter activity
GXN76_10480	COG1136	(ABC) transporter
GXN76_10485	COG2205	protein histidine kinase activity
GXN76_10490	COG0745	RESPONSE REGULATOR receiver
GXN76_10495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GXN76_10500	COG4208	sulfate ABC transporter
GXN76_10505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GXN76_10510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GXN76_10525	COG1408	metallophosphoesterase
GXN76_10535	COG0726	polysaccharide deacetylase
GXN76_10545	COG0861	Integral membrane protein TerC family
GXN76_10550	COG4187	Peptidase family M20/M25/M40
GXN76_10555	COG0301	tRNA thio-modification
GXN76_10560	COG1104	cysteine desulfurase activity
GXN76_10575	COG0583	DNA-binding transcription factor activity
GXN76_10580	COG2814	Major facilitator Superfamily
GXN76_10585	COG1132	(ABC) transporter
GXN76_10595	COG4085	toxin activity
GXN76_10595	COG1525	nuclease
GXN76_10595	COG0737	Belongs to the 5'-nucleotidase family
GXN76_10610	COG1309	transcriptional regulator
GXN76_10660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GXN76_10690	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_10710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GXN76_10715	COG2233	PERMEase
GXN76_10755	COG4709	membrane
GXN76_10760	COG1238	metal cluster binding
GXN76_10765	COG0791	NLP P60 protein
GXN76_10775	COG3599	regulation of cell shape
GXN76_10785	COG2738	Putative neutral zinc metallopeptidase
GXN76_10790	COG0475	glutathione-regulated potassium exporter activity
GXN76_10805	COG0772	Belongs to the SEDS family
GXN76_10810	COG0772	Belongs to the SEDS family
GXN76_10815	COG2022	thiamine diphosphate biosynthetic process
GXN76_10820	COG2022	thiamine diphosphate biosynthetic process
GXN76_10820	COG2104	thiamine diphosphate biosynthetic process
GXN76_10825	COG0352	thiamine-phosphate diphosphorylase activity
GXN76_10840	COG0586	Pfam SNARE associated Golgi protein
GXN76_10850	COG4821	SIS domain
GXN76_10855	COG0363	glucosamine-6-phosphate deaminase activity
GXN76_10860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GXN76_10865	COG1363	Peptidase, m42
GXN76_10875	COG2755	lipolytic protein G-D-S-L family
GXN76_10885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GXN76_10890	COG2384	SAM-dependent methyltransferase
GXN76_10905	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_10910	COG1960	acyl-CoA dehydrogenase activity
GXN76_10920	COG0358	DNA primase activity
GXN76_10925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GXN76_10925	COG0574	Belongs to the PEP-utilizing enzyme family
GXN76_10930	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GXN76_10935	COG0517	IMP dehydrogenase activity
GXN76_10940	COG0751	glycine-tRNA ligase activity
GXN76_10945	COG0752	glycyl-tRNA synthetase alpha subunit
GXN76_10950	COG1381	Involved in DNA repair and RecF pathway recombination
GXN76_10960	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GXN76_10975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GXN76_10980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GXN76_10985	COG1480	7TM receptor with intracellular HD hydrolase
GXN76_10990	COG1702	phosphate starvation-inducible protein PhoH
GXN76_11015	COG4864	UPF0365 protein
GXN76_11020	COG1030	water channel activity
GXN76_11025	COG1610	YqeY-like protein
GXN76_11030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GXN76_11035	COG0537	adenosine 5'-monophosphoramidase activity
GXN76_11045	COG1283	sodium-dependent phosphate transmembrane transporter activity
GXN76_11050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GXN76_11065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GXN76_11070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GXN76_11075	COG2264	protein methyltransferase activity
GXN76_11080	COG0484	heat shock protein binding
GXN76_11085	COG0443	Heat shock 70 kDa protein
GXN76_11095	COG0459	protein refolding
GXN76_11100	COG1420	regulation of RNA biosynthetic process
GXN76_11105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GXN76_11110	COG0481	GTPase activity
GXN76_11125	COG0860	N-Acetylmuramoyl-L-alanine amidase
GXN76_11130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GXN76_11135	COG0268	Binds directly to 16S ribosomal RNA
GXN76_11140	COG0180	Tryptophanyl-tRNA synthetase
GXN76_11145	COG4846	Membrane protein involved in cytochrome C biogenesis
GXN76_11150	COG1683	Conserved Protein
GXN76_11155	COG1233	COG1233 Phytoene dehydrogenase and related
GXN76_11160	COG1466	dna polymerase III delta subunit
GXN76_11165	COG0702	epimerase
GXN76_11185	COG2333	competence protein COMEC
GXN76_11185	COG0658	competence protein
GXN76_11190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_11195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GXN76_11205	COG0717	Belongs to the dCTP deaminase family
GXN76_11210	COG0626	cystathionine gamma-synthase activity
GXN76_11215	COG0626	cystathionine gamma-synthase activity
GXN76_11225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GXN76_11240	COG1555	photosystem II stabilization
GXN76_11240	COG1596	polysaccharide export
GXN76_11245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GXN76_11260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GXN76_11280	COG0799	negative regulation of ribosome biogenesis
GXN76_11285	COG1713	HD superfamily hydrolase involved in NAD metabolism
GXN76_11290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GXN76_11295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GXN76_11300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GXN76_11305	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GXN76_11320	COG1131	(ABC) transporter
GXN76_11340	COG0561	phosphatase activity
GXN76_11350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GXN76_11370	COG1876	peptidase activity
GXN76_11375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GXN76_11380	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_11385	COG0506	proline dehydrogenase activity
GXN76_11390	COG3829	transcription factor binding
GXN76_11390	COG3290	protein histidine kinase activity
GXN76_11410	COG2124	cytochrome p450
GXN76_11425	COG0753	catalase activity
GXN76_11440	COG5577	PFAM Coat F domain
GXN76_11445	COG5577	PFAM Coat F domain
GXN76_11455	COG1131	(ABC) transporter
GXN76_11460	COG3559	Exporter of polyketide antibiotics
GXN76_11475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GXN76_11485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GXN76_11505	COG2091	lysine biosynthetic process via aminoadipic acid
GXN76_11510	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_11525	COG0588	phosphoglycerate mutase activity
GXN76_11540	COG1070	Carbohydrate kinase
GXN76_11545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GXN76_11550	COG2814	Major facilitator Superfamily
GXN76_11570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GXN76_11575	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_11620	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_11625	COG0460	homoserine dehydrogenase
GXN76_11630	COG1473	amidohydrolase
GXN76_11640	COG0006	proline dipeptidase activity
GXN76_11645	COG2508	Transcriptional regulator
GXN76_11650	COG1126	abc transporter atp-binding protein
GXN76_11655	COG0765	amino acid transport
GXN76_11660	COG0765	amino acid transport
GXN76_11665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GXN76_11675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GXN76_11680	COG1917	Cupin 2, conserved barrel domain protein
GXN76_11685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GXN76_11690	COG0768	penicillin binding
GXN76_11695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GXN76_11700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GXN76_11710	COG3906	Belongs to the UPF0473 family
GXN76_11715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GXN76_11720	COG4472	Bacterial protein of unknown function (DUF965)
GXN76_11725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GXN76_11730	COG0628	permease
GXN76_11750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GXN76_11770	COG0740	serine-type endopeptidase activity
GXN76_11780	COG1397	ADP-ribosylglycohydrolase
GXN76_11785	COG3858	chitin binding
GXN76_11785	COG1388	LysM domain
GXN76_11795	COG1104	cysteine desulfurase activity
GXN76_11800	COG1959	2 iron, 2 sulfur cluster binding
GXN76_11805	COG2364	Membrane
GXN76_11820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXN76_11840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GXN76_11845	COG0124	histidyl-tRNA synthetase
GXN76_11855	COG4149	molybdate abc transporter
GXN76_11860	COG0725	ABC transporter, periplasmic molybdate-binding protein
GXN76_11865	COG0584	glycerophosphoryl diester phosphodiesterase
GXN76_11875	COG0475	glutathione-regulated potassium exporter activity
GXN76_11910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GXN76_11920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GXN76_11935	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GXN76_11940	COG2346	COG2346, Truncated hemoglobins
GXN76_11945	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GXN76_11960	COG3541	Predicted nucleotidyltransferase
GXN76_11970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GXN76_11975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GXN76_11985	COG0477	Major facilitator Superfamily
GXN76_11990	COG0705	Rhomboid family
GXN76_11995	COG0688	phosphatidylethanolamine metabolic process
GXN76_12010	COG1404	Belongs to the peptidase S8 family
GXN76_12045	COG2205	protein histidine kinase activity
GXN76_12050	COG0745	RESPONSE REGULATOR receiver
GXN76_12055	COG2207	Transcriptional regulator
GXN76_12055	COG3708	Transcriptional regulator
GXN76_12065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GXN76_12085	COG3546	catalase activity
GXN76_12110	COG0326	Molecular chaperone. Has ATPase activity
GXN76_12115	COG0730	response to heat
GXN76_12120	COG0425	Belongs to the sulfur carrier protein TusA family
GXN76_12125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GXN76_12125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GXN76_12135	COG0425	Belongs to the sulfur carrier protein TusA family
GXN76_12135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GXN76_12140	COG2210	Belongs to the sulfur carrier protein TusA family
GXN76_12145	COG1193	negative regulation of DNA recombination
GXN76_12165	COG0783	Belongs to the Dps family
GXN76_12205	COG2894	cell division
GXN76_12210	COG3339	Conserved Protein
GXN76_12220	COG2814	Major facilitator Superfamily
GXN76_12255	COG2239	Acts as a magnesium transporter
GXN76_12260	COG1253	flavin adenine dinucleotide binding
GXN76_12270	COG4641	Protein conserved in bacteria
GXN76_12285	COG0613	PHP domain protein
GXN76_12290	COG1316	TRANSCRIPTIONal
GXN76_12330	COG1404	Belongs to the peptidase S8 family
GXN76_12340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GXN76_12350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GXN76_12365	COG0517	IMP dehydrogenase activity
GXN76_12370	COG2323	membrane
GXN76_12385	COG1725	Transcriptional regulator
GXN76_12390	COG1131	(ABC) transporter
GXN76_12395	COG1131	(ABC) transporter
GXN76_12400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GXN76_12405	COG1473	amidohydrolase
GXN76_12415	COG1302	Protein conserved in bacteria
GXN76_12420	COG1028	Short-chain dehydrogenase reductase Sdr
GXN76_12430	COG0372	Belongs to the citrate synthase family
GXN76_12435	COG0583	DNA-binding transcription factor activity
GXN76_12455	COG3226	Transcriptional regulator
GXN76_12475	COG4838	Belongs to the UPF0358 family
GXN76_12480	COG2066	Belongs to the glutaminase family
GXN76_12485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GXN76_12495	COG1363	Peptidase, m42
GXN76_12500	COG2002	toxin-antitoxin pair type II binding
GXN76_12505	COG1115	amino acid carrier protein
GXN76_12515	COG2309	aminopeptidase activity
GXN76_12520	COG1956	GAF domain-containing protein
GXN76_12525	COG0494	nUDIX hydrolase
GXN76_12535	COG0477	Major facilitator Superfamily
GXN76_12545	COG1597	lipid kinase activity
GXN76_12550	COG0671	phosphoesterase, PA-phosphatase related
GXN76_12580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GXN76_12585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GXN76_12590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GXN76_12595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_12600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GXN76_12605	COG0454	-acetyltransferase
GXN76_12610	COG0123	including yeast histone deacetylase and acetoin utilization protein
GXN76_12615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GXN76_12620	COG1609	Transcriptional regulator
GXN76_12625	COG1605	Chorismate mutase
GXN76_12625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GXN76_12645	COG4980	gas vesicle protein
GXN76_12655	COG1472	Belongs to the glycosyl hydrolase 3 family
GXN76_12660	COG0538	isocitrate dehydrogenase activity
GXN76_12675	COG0583	DNA-binding transcription factor activity
GXN76_12690	COG2076	Multidrug Resistance protein
GXN76_12695	COG2076	Multidrug Resistance protein
GXN76_12745	COG1832	CoA-binding protein
GXN76_12750	COG0069	glutamate synthase activity
GXN76_12755	COG1902	pentaerythritol trinitrate reductase activity
GXN76_12760	COG2112	serine threonine protein kinase
GXN76_12775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GXN76_12780	COG1607	acyl-coa hydrolase
GXN76_12795	COG1316	TRANSCRIPTIONal
GXN76_12800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GXN76_12805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GXN76_12810	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_12815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GXN76_12820	COG0066	3-isopropylmalate dehydratase activity
GXN76_12825	COG1834	amidinotransferase
GXN76_12840	COG1268	BioY protein
GXN76_12845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GXN76_12850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GXN76_12855	COG0745	RESPONSE REGULATOR receiver
GXN76_12860	COG2205	protein histidine kinase activity
GXN76_12875	COG0671	phosphoesterase, PA-phosphatase related
GXN76_12885	COG0745	RESPONSE REGULATOR receiver
GXN76_12890	COG2205	protein histidine kinase activity
GXN76_12900	COG1733	regulation of RNA biosynthetic process
GXN76_12920	COG0640	Transcriptional regulator
GXN76_12925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GXN76_12930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GXN76_12935	COG0640	Transcriptional regulator
GXN76_12940	COG0346	lactoylglutathione lyase activity
GXN76_12945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GXN76_12970	COG0154	amidase activity
GXN76_12990	COG3011	Protein conserved in bacteria
GXN76_12995	COG2814	Major facilitator Superfamily
GXN76_13000	COG1760	l-serine dehydratase
GXN76_13005	COG1760	l-serine dehydratase
GXN76_13010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GXN76_13015	COG2427	Protein of unknown function (DUF1641)
GXN76_13020	COG3383	formate dehydrogenase (NAD+) activity
GXN76_13025	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_13035	COG2046	Belongs to the sulfate adenylyltransferase family
GXN76_13040	COG0175	sulfate reduction
GXN76_13050	COG0456	acetyltransferase
GXN76_13050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GXN76_13060	COG3773	Cell wall hydrolase
GXN76_13065	COG0460	homoserine dehydrogenase
GXN76_13085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GXN76_13110	COG4166	transmembrane transport
GXN76_13115	COG1876	peptidase activity
GXN76_13120	COG0534	Mate efflux family protein
GXN76_13125	COG1704	LemA family
GXN76_13130	COG0501	Belongs to the peptidase M48B family
GXN76_13135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GXN76_13170	COG0612	Peptidase, M16
GXN76_13230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GXN76_13235	COG0157	Belongs to the NadC ModD family
GXN76_13240	COG1104	cysteine desulfurase activity
GXN76_13250	COG0628	permease
GXN76_13255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GXN76_13275	COG0306	phosphate transporter
GXN76_13280	COG1392	Phosphate transport regulator
GXN76_13285	COG2409	Drug exporters of the RND superfamily
GXN76_13285	COG1033	growth of symbiont in host cell
GXN76_13290	COG5002	protein histidine kinase activity
GXN76_13300	COG3397	chitin binding
GXN76_13320	COG1131	(ABC) transporter
GXN76_13345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GXN76_13345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GXN76_13350	COG2814	Major facilitator Superfamily
GXN76_13370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GXN76_13385	COG0659	secondary active sulfate transmembrane transporter activity
GXN76_13390	COG0697	spore germination
GXN76_13395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GXN76_13400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXN76_13410	COG1509	lysine 2,3-aminomutase activity
GXN76_13415	COG0482	sulfurtransferase activity
GXN76_13425	COG1404	Belongs to the peptidase S8 family
GXN76_13430	COG3858	chitin binding
GXN76_13530	COG2252	PERMEase
GXN76_13535	COG0519	Catalyzes the synthesis of GMP from XMP
GXN76_13535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GXN76_13550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GXN76_13570	COG0577	efflux transmembrane transporter activity
GXN76_13570	COG1136	(ABC) transporter
GXN76_13600	COG2205	protein histidine kinase activity
GXN76_13605	COG0745	RESPONSE REGULATOR receiver
GXN76_13610	COG0745	RESPONSE REGULATOR receiver
GXN76_13660	COG0640	Transcriptional regulator
GXN76_13670	COG0459	protein refolding
GXN76_13675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GXN76_13680	COG0805	protein transport
GXN76_13685	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GXN76_13690	COG0521	Mo-molybdopterin cofactor biosynthetic process
GXN76_13690	COG0315	cyclic pyranopterin monophosphate synthase activity
GXN76_13710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GXN76_13725	COG0488	(ABC) transporter
GXN76_13735	COG1984	allophanate hydrolase subunit 2
GXN76_13740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GXN76_13745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GXN76_13750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GXN76_13755	COG0456	acetyltransferase
GXN76_13760	COG1214	PFAM Peptidase M22, glycoprotease
GXN76_13765	COG0802	atpase or kinase
GXN76_13770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GXN76_13835	COG0521	Mo-molybdopterin cofactor biosynthetic process
GXN76_13840	COG0315	cyclic pyranopterin monophosphate synthase activity
GXN76_13845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GXN76_13855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXN76_13860	COG0670	Belongs to the BI1 family
GXN76_13870	COG0314	molybdopterin synthase activity
GXN76_13875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GXN76_13880	COG2084	Dehydrogenase
GXN76_13900	COG3091	SprT-like family
GXN76_13920	COG0739	heme binding
GXN76_13925	COG2183	response to ionizing radiation
GXN76_13930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GXN76_13935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GXN76_13945	COG0745	RESPONSE REGULATOR receiver
GXN76_13950	COG5002	protein histidine kinase activity
GXN76_13960	COG1191	sigma factor activity
GXN76_13965	COG2172	sigma factor antagonist activity
GXN76_13975	COG2208	phosphoserine phosphatase activity
GXN76_13980	COG2337	Toxic component of a toxin-antitoxin (TA) module
GXN76_13985	COG0864	Transcriptional regulator
GXN76_13990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GXN76_14010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GXN76_14015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GXN76_14015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GXN76_14020	COG0736	holo-[acyl-carrier-protein] synthase activity
GXN76_14030	COG1131	(ABC) transporter
GXN76_14040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_14045	COG1174	glycine betaine transport
GXN76_14070	COG2268	Band 7 protein
GXN76_14075	COG2971	BadF BadG BcrA BcrD
GXN76_14085	COG1447	Phosphotransferase system cellobiose-specific component IIA
GXN76_14095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GXN76_14100	COG2188	Transcriptional regulator
GXN76_14105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GXN76_14110	COG1486	melibiose metabolic process
GXN76_14115	COG2217	Heavy metal translocating P-type atpase
GXN76_14120	COG2363	Small membrane protein
GXN76_14125	COG1295	ribonuclease BN
GXN76_14130	COG1115	amino acid carrier protein
GXN76_14135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GXN76_14145	COG2188	Transcriptional regulator
GXN76_14165	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GXN76_14170	COG0626	cystathionine gamma-synthase activity
GXN76_14175	COG3457	Alanine racemase
GXN76_14180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GXN76_14210	COG0019	diaminopimelate decarboxylase activity
GXN76_14215	COG4264	IucA IucC family
GXN76_14220	COG2423	ornithine cyclodeaminase activity
GXN76_14230	COG4264	IucA IucC family
GXN76_14240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_14245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXN76_14250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GXN76_14260	COG2936	dipeptidyl-peptidase activity
GXN76_14275	COG3848	Pyruvate phosphate dikinase
GXN76_14275	COG0574	Belongs to the PEP-utilizing enzyme family
GXN76_14280	COG3848	Pyruvate phosphate dikinase
GXN76_14280	COG0574	Belongs to the PEP-utilizing enzyme family
GXN76_14285	COG2814	Major facilitator Superfamily
GXN76_14295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GXN76_14300	COG2514	catechol 2,3-dioxygenase activity
GXN76_14305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXN76_14320	COG3832	glyoxalase III activity
GXN76_14325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GXN76_14330	COG0789	Transcriptional regulator
GXN76_14370	COG0477	Major facilitator Superfamily
GXN76_14375	COG1309	transcriptional regulator
GXN76_14395	COG2217	Heavy metal translocating P-type atpase
GXN76_14400	COG2608	mercury ion transmembrane transporter activity
GXN76_14405	COG1937	Protein conserved in bacteria
GXN76_14410	COG0583	DNA-binding transcription factor activity
GXN76_14420	COG0604	alcohol dehydrogenase
GXN76_14435	COG1279	arginine transmembrane transporter activity
GXN76_14465	COG0336	Belongs to the RNA methyltransferase TrmD family
GXN76_14470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GXN76_14480	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GXN76_14485	COG1595	DNA-templated transcription, initiation
GXN76_14490	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GXN76_14570	COG1309	transcriptional regulator
GXN76_14585	COG0726	polysaccharide deacetylase
GXN76_14600	COG0390	transport system, permease component
GXN76_14605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GXN76_14610	COG0489	protein tyrosine kinase activity
GXN76_14615	COG0860	N-Acetylmuramoyl-L-alanine amidase
GXN76_14630	COG1902	pentaerythritol trinitrate reductase activity
GXN76_14635	COG1522	sequence-specific DNA binding
GXN76_14640	COG0583	DNA-binding transcription factor activity
GXN76_14645	COG2962	Rard protein
GXN76_14655	COG0656	L-ascorbic acid biosynthetic process
GXN76_14675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GXN76_14680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GXN76_14685	COG0101	tRNA pseudouridine synthase activity
GXN76_14690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GXN76_14695	COG1122	ATPase activity
GXN76_14700	COG1122	ATPase activity
GXN76_14705	COG0203	ribosomal protein L17
GXN76_14710	COG0202	RNA polymerase activity
GXN76_14715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GXN76_14720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GXN76_14725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GXN76_14730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GXN76_14740	COG0024	Methionine aminopeptidase
GXN76_14745	COG0563	adenylate kinase activity
GXN76_14750	COG0201	protein transport
GXN76_14755	COG0200	Binds to the 23S rRNA
GXN76_14760	COG1841	ribosomal large subunit assembly
GXN76_14765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GXN76_14770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GXN76_14775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GXN76_14780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GXN76_14790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GXN76_14795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GXN76_14800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GXN76_14805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GXN76_14810	COG0255	Belongs to the universal ribosomal protein uL29 family
GXN76_14815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GXN76_14820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GXN76_14825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GXN76_14830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GXN76_14835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GXN76_14840	COG0089	rRNA binding
GXN76_14845	COG0088	Forms part of the polypeptide exit tunnel
GXN76_14850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GXN76_14855	COG0051	transcription antitermination factor activity, RNA binding
GXN76_14870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GXN76_14875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GXN76_14880	COG0049	tRNA binding
GXN76_14885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GXN76_14890	COG1358	cellular component organization or biogenesis
GXN76_14895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GXN76_14900	COG0085	RNA polymerase activity
GXN76_14905	COG2813	Specifically methylates the guanine in position
GXN76_14910	COG0222	ribosome binding
GXN76_14915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GXN76_14920	COG0081	regulation of translation
GXN76_14925	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GXN76_14930	COG0250	Participates in transcription elongation, termination and antitermination
GXN76_14940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GXN76_14955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GXN76_14960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GXN76_14965	COG0215	cysteine-tRNA ligase activity
GXN76_14970	COG1045	serine acetyltransferase
GXN76_14975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GXN76_14990	COG4956	integral membrane protein (PIN domain superfamily)
GXN76_14995	COG1329	Transcriptional regulator
GXN76_15005	COG1183	phosphatidylcholine synthase activity
GXN76_15010	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GXN76_15015	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GXN76_15020	COG0542	response to heat
GXN76_15025	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GXN76_15030	COG3880	PFAM UvrB UvrC protein
GXN76_15040	COG1285	pathogenesis
GXN76_15045	COG0546	phosphoglycolate phosphatase activity
GXN76_15050	COG4129	membrane
GXN76_15065	COG0577	efflux transmembrane transporter activity
GXN76_15070	COG1136	(ABC) transporter
GXN76_15075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GXN76_15085	COG2205	protein histidine kinase activity
GXN76_15090	COG0745	RESPONSE REGULATOR receiver
GXN76_15125	COG3599	regulation of cell shape
GXN76_15140	COG2270	Major facilitator Superfamily
GXN76_15155	COG0456	acetyltransferase
GXN76_15160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GXN76_15165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GXN76_15170	COG0505	Belongs to the CarA family
GXN76_15180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GXN76_15185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GXN76_15190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GXN76_15205	COG1024	Enoyl-CoA hydratase
GXN76_15210	COG1413	lyase activity
GXN76_15215	COG3878	Protein conserved in bacteria
GXN76_15230	COG0653	protein targeting
GXN76_15235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GXN76_15240	COG1278	Cold shock
GXN76_15250	COG1040	competence protein
GXN76_15255	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GXN76_15265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GXN76_15275	COG1739	Uncharacterized protein family UPF0029
GXN76_15280	COG1464	Belongs to the NlpA lipoprotein family
GXN76_15285	COG2011	ABC-type metal ion transport system permease component
GXN76_15290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GXN76_15295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GXN76_15300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GXN76_15305	COG1012	belongs to the aldehyde dehydrogenase family
GXN76_15315	COG1316	TRANSCRIPTIONal
GXN76_15325	COG0438	transferase activity, transferring glycosyl groups
GXN76_15330	COG3307	-O-antigen
GXN76_15355	COG0673	inositol 2-dehydrogenase activity
GXN76_15360	COG0297	glycogen (starch) synthase activity
GXN76_15360	COG0438	transferase activity, transferring glycosyl groups
GXN76_15375	COG0281	malic enzyme
GXN76_15380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GXN76_15390	COG1609	Transcriptional regulator
GXN76_15395	COG0739	heme binding
GXN76_15400	COG2385	sporulation resulting in formation of a cellular spore
GXN76_15405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GXN76_15425	COG1131	(ABC) transporter
GXN76_15430	COG1007	ATP synthesis coupled electron transport
GXN76_15435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXN76_15440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GXN76_15450	COG0839	Belongs to the complex I subunit 6 family
GXN76_15460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GXN76_15465	COG0649	NAD binding
GXN76_15470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXN76_15475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXN76_15485	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GXN76_15490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GXN76_15495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GXN76_15510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GXN76_15520	COG0356	it plays a direct role in the translocation of protons across the membrane
GXN76_15535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GXN76_15545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GXN76_15550	COG4475	Protein of unknown function (DUF436)
GXN76_15555	COG0698	ribose 5-phosphate isomerase
GXN76_15560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GXN76_15570	COG1971	Probably functions as a manganese efflux pump
GXN76_15575	COG0009	L-threonylcarbamoyladenylate synthase
GXN76_15590	COG2890	protein-(glutamine-N5) methyltransferase activity
GXN76_15595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GXN76_15630	COG0254	rRNA binding
GXN76_15635	COG0741	lytic transglycosylase activity
GXN76_15635	COG1196	nuclear chromosome segregation
GXN76_15635	COG0739	heme binding
GXN76_15640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GXN76_15645	COG1494	fructose-1,6-bisphosphatase
GXN76_15650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GXN76_15655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GXN76_15660	COG0191	fructose-bisphosphate aldolase activity
GXN76_15665	COG3246	L-lysine catabolic process to acetate
GXN76_15670	COG1607	acyl-coa hydrolase
GXN76_15675	COG2204	response regulator
GXN76_15680	COG0504	CTP synthase activity
GXN76_15685	COG3343	RNA polymerase activity
GXN76_15690	COG1703	isobutyryl-CoA mutase activity
GXN76_15690	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_15690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_15700	COG1703	isobutyryl-CoA mutase activity
GXN76_15705	COG1960	acyl-CoA dehydrogenase activity
GXN76_15710	COG1960	acyl-CoA dehydrogenase activity
GXN76_15715	COG1250	3-hydroxyacyl-CoA dehydrogenase
GXN76_15720	COG0183	Belongs to the thiolase family
GXN76_15740	COG0247	lactate metabolic process
GXN76_15740	COG2181	nitrate reductase activity
GXN76_15745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GXN76_15750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GXN76_15755	COG1193	negative regulation of DNA recombination
GXN76_15765	COG1509	lysine 2,3-aminomutase activity
GXN76_15770	COG0604	alcohol dehydrogenase
GXN76_15775	COG3829	transcription factor binding
GXN76_15815	COG0714	Associated with various cellular activities
GXN76_15820	COG0018	arginyl-trna synthetase
GXN76_15830	COG0010	Belongs to the arginase family
GXN76_15835	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GXN76_15845	COG0640	Transcriptional regulator
GXN76_15850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXN76_15865	COG3852	Histidine kinase
GXN76_15870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXN76_15870	COG1263	PTS System
GXN76_15890	COG0745	RESPONSE REGULATOR receiver
GXN76_15895	COG5002	protein histidine kinase activity
GXN76_15910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GXN76_15915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GXN76_15925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GXN76_15930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GXN76_15935	COG0305	Participates in initiation and elongation during chromosome replication
GXN76_15940	COG0359	binds to the 23S rRNA
GXN76_15945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GXN76_15960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GXN76_15965	COG0629	single-stranded DNA binding
GXN76_15970	COG0360	Binds together with S18 to 16S ribosomal RNA
GXN76_15975	COG0012	GTP binding
GXN76_15980	COG4481	Protein conserved in bacteria
GXN76_15985	COG0318	PFAM AMP-dependent synthetase and ligase
GXN76_15985	COG0204	Acyl-transferase
GXN76_15990	COG3949	Membrane
GXN76_16000	COG1597	lipid kinase activity
GXN76_16010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GXN76_16015	COG1475	DNA binding
GXN76_16020	COG1192	Involved in chromosome partitioning
GXN76_16030	COG1475	DNA binding
GXN76_16045	COG0357	Ribosomal RNA small subunit methyltransferase G
GXN76_16050	COG0445	tRNA wobble uridine modification
GXN76_16055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GXN76_16060	COG1847	R3H domain protein
GXN76_16065	COG0706	membrane insertase activity
GXN76_16070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GXN76_16080	COG0230	Belongs to the bacterial ribosomal protein bL34 family