locus-tag	class	description
B0E33_00005	COG0583	DNA-binding transcription factor activity
B0E33_00035	COG1741	Belongs to the pirin family
B0E33_00050	COG1940	carbohydrate kinase activity
B0E33_00060	COG1846	Transcriptional regulator
B0E33_00085	COG0512	Glutamine amidotransferase of anthranilate synthase
B0E33_00085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B0E33_00105	COG5001	Diguanylate cyclase
B0E33_00105	COG3300	MHYT domain
B0E33_00115	COG0129	dihydroxy-acid dehydratase activity
B0E33_00130	COG1902	pentaerythritol trinitrate reductase activity
B0E33_00135	COG1309	transcriptional regulator
B0E33_00160	COG3119	arylsulfatase activity
B0E33_00180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B0E33_00200	COG0540	Belongs to the ATCase OTCase family
B0E33_00205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B0E33_00215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B0E33_00220	COG0758	DNA mediated transformation
B0E33_00225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B0E33_00230	COG0557	exoribonuclease II activity
B0E33_00270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B0E33_00295	COG0456	acetyltransferase
B0E33_00305	COG0583	DNA-binding transcription factor activity
B0E33_00320	COG3257	ureidoglycine aminohydrolase activity
B0E33_00325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0E33_00340	COG2200	EAL domain
B0E33_00345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_00355	COG1132	(ABC) transporter
B0E33_00360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B0E33_00365	COG0489	protein tyrosine kinase activity
B0E33_00370	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B0E33_00380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B0E33_00390	COG0628	permease
B0E33_00400	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B0E33_00405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B0E33_00420	COG1120	ATPase activity
B0E33_00425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_00435	COG2226	methyltransferase
B0E33_00445	COG2186	Transcriptional regulator
B0E33_00450	COG3842	ATPase activity
B0E33_00460	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_00505	COG4172	Belongs to the ABC transporter superfamily
B0E33_00510	COG2354	Protein conserved in bacteria
B0E33_00515	COG0519	Catalyzes the synthesis of GMP from XMP
B0E33_00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_00540	COG0243	molybdopterin cofactor binding
B0E33_00555	COG0105	UTP biosynthetic process
B0E33_00565	COG2207	Transcriptional regulator
B0E33_00565	COG1917	Cupin 2, conserved barrel domain protein
B0E33_00575	COG0488	(ABC) transporter
B0E33_00595	COG2927	DNA polymerase III (CHI subunit)
B0E33_00600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B0E33_00620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B0E33_00625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B0E33_00630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B0E33_00640	COG0194	GDP metabolic process
B0E33_00645	COG1561	YicC-like family, N-terminal region
B0E33_00650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B0E33_00655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B0E33_00660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0E33_00670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B0E33_00680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B0E33_00690	COG0305	Participates in initiation and elongation during chromosome replication
B0E33_00700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B0E33_00710	COG1286	toxin biosynthetic process
B0E33_00715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B0E33_00720	COG4221	oxidoreductase activity
B0E33_00740	COG1160	GTP binding
B0E33_00745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0E33_00765	COG0735	belongs to the Fur family
B0E33_00770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0E33_00775	COG1121	(ABC) transporter
B0E33_00800	COG1695	Transcriptional regulator
B0E33_00825	COG1183	phosphatidylcholine synthase activity
B0E33_00830	COG0688	phosphatidylethanolamine metabolic process
B0E33_00835	COG0583	DNA-binding transcription factor activity
B0E33_00845	COG5265	(ABC) transporter
B0E33_00855	COG1652	LysM domain
B0E33_00865	COG0745	RESPONSE REGULATOR receiver
B0E33_00865	COG3706	GGDEF domain
B0E33_00875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B0E33_00895	COG0215	cysteine-tRNA ligase activity
B0E33_00900	COG2989	Protein conserved in bacteria
B0E33_00910	COG0640	Transcriptional regulator
B0E33_00915	COG3045	CreA protein
B0E33_00935	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B0E33_00935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B0E33_00955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B0E33_00970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B0E33_00980	COG5002	protein histidine kinase activity
B0E33_00980	COG5001	Diguanylate cyclase
B0E33_00980	COG3447	MASE1 domain protein
B0E33_00995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B0E33_01000	COG0840	transmembrane signaling receptor activity
B0E33_01010	COG0546	phosphoglycolate phosphatase activity
B0E33_01035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0E33_01040	COG1083	cytidylyl-transferase
B0E33_01050	COG2089	acid synthase
B0E33_01085	COG3214	Protein conserved in bacteria
B0E33_01105	COG1063	alcohol dehydrogenase
B0E33_01110	COG0156	8-amino-7-oxononanoate synthase activity
B0E33_01115	COG1280	lysine exporter protein (LysE YggA)
B0E33_01140	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B0E33_01150	COG1309	transcriptional regulator
B0E33_01155	COG5012	cobalamin binding
B0E33_01170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B0E33_01175	COG0646	methionine synthase
B0E33_01175	COG1410	methionine synthase
B0E33_01200	COG2207	Transcriptional regulator
B0E33_01200	COG3708	Transcriptional regulator
B0E33_01205	COG1832	CoA-binding protein
B0E33_01220	COG1612	heme a metabolic process
B0E33_01525	COG4974	Belongs to the 'phage' integrase family
B0E33_01535	COG1403	HNH endonuclease
B0E33_01640	COG0438	transferase activity, transferring glycosyl groups
B0E33_01640	COG1216	Glycosyl transferase, family 2
B0E33_01650	COG1091	dTDP-4-dehydrorhamnose reductase activity
B0E33_01655	COG1088	dTDP-glucose 4,6-dehydratase activity
B0E33_01660	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B0E33_01670	COG0747	negative chemotaxis
B0E33_01680	COG0601	transmembrane transport
B0E33_01690	COG0444	Belongs to the ABC transporter superfamily
B0E33_01695	COG4608	Belongs to the ABC transporter superfamily
B0E33_01715	COG2124	cytochrome p450
B0E33_01735	COG0776	regulation of translation
B0E33_01740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B0E33_01745	COG0416	fatty acid biosynthetic process
B0E33_01765	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B0E33_01770	COG2814	Major facilitator Superfamily
B0E33_01775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B0E33_01785	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B0E33_01795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B0E33_01795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B0E33_01800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B0E33_01805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B0E33_01815	COG2989	Protein conserved in bacteria
B0E33_01820	COG1846	Transcriptional regulator
B0E33_01835	COG1024	Enoyl-CoA hydratase
B0E33_01840	COG1960	acyl-CoA dehydrogenase activity
B0E33_01845	COG0113	porphobilinogen synthase activity
B0E33_01850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B0E33_01860	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B0E33_01865	COG3273	potassium ion transport
B0E33_01865	COG0471	metal ion transport
B0E33_01870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B0E33_01875	COG1573	uracil-dna glycosylase
B0E33_01885	COG1758	RNA polymerase activity
B0E33_01895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B0E33_01905	COG0736	holo-[acyl-carrier-protein] synthase activity
B0E33_01910	COG0681	Belongs to the peptidase S26 family
B0E33_01915	COG0571	ribonuclease III activity
B0E33_01920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B0E33_01925	COG1381	Involved in DNA repair and RecF pathway recombination
B0E33_01930	COG0681	Belongs to the peptidase S26 family
B0E33_01935	COG5001	Diguanylate cyclase
B0E33_01940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B0E33_01945	COG2207	Transcriptional regulator
B0E33_01945	COG1917	Cupin 2, conserved barrel domain protein
B0E33_01955	COG1454	alcohol dehydrogenase
B0E33_01965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B0E33_01970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_01975	COG0596	Alpha beta hydrolase
B0E33_01975	COG2945	thiolester hydrolase activity
B0E33_01990	COG4953	penicillin-binding protein 1C
B0E33_02000	COG1192	Involved in chromosome partitioning
B0E33_02010	COG2951	lytic endotransglycosylase activity
B0E33_02015	COG3639	organic phosphonate transmembrane transporter activity
B0E33_02025	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B0E33_02030	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B0E33_02065	COG1522	sequence-specific DNA binding
B0E33_02080	COG0673	inositol 2-dehydrogenase activity
B0E33_02090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0E33_02095	COG4989	oxidoreductase activity
B0E33_02100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0E33_02130	COG2855	membrane
B0E33_02135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0E33_02135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0E33_02140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_02155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B0E33_02160	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B0E33_02165	COG2267	carboxylic ester hydrolase activity
B0E33_02185	COG0589	response to stress
B0E33_02190	COG0583	DNA-binding transcription factor activity
B0E33_02195	COG0006	proline dipeptidase activity
B0E33_02210	COG0625	glutathione transferase activity
B0E33_02220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B0E33_02230	COG0673	inositol 2-dehydrogenase activity
B0E33_02235	COG0395	ABC-type sugar transport system, permease component
B0E33_02260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_02265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_02280	COG0395	ABC-type sugar transport system, permease component
B0E33_02320	COG1129	ABC transporter
B0E33_02330	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_02350	COG1024	Enoyl-CoA hydratase
B0E33_02360	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_02370	COG1609	Transcriptional regulator
B0E33_02375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_02380	COG1869	D-ribose catabolic process
B0E33_02385	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_02390	COG1129	ABC transporter
B0E33_02395	COG1879	ABC-type sugar transport system periplasmic component
B0E33_02430	COG0747	negative chemotaxis
B0E33_02440	COG2197	response regulator
B0E33_02445	COG1177	transmembrane transport
B0E33_02455	COG3842	ATPase activity
B0E33_02465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_02475	COG4221	oxidoreductase activity
B0E33_02480	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0E33_02490	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_02500	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_02505	COG2721	sulfolactate sulfo-lyase activity
B0E33_02510	COG1802	Transcriptional regulator
B0E33_02520	COG4154	Belongs to the RbsD FucU family
B0E33_02550	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_02560	COG3842	ATPase activity
B0E33_02595	COG1846	Transcriptional regulator
B0E33_02605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B0E33_02615	COG0747	negative chemotaxis
B0E33_02620	COG0601	transmembrane transport
B0E33_02625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_02630	COG0444	Belongs to the ABC transporter superfamily
B0E33_02670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B0E33_02750	COG0765	amino acid transport
B0E33_02755	COG0765	amino acid transport
B0E33_02765	COG1309	transcriptional regulator
B0E33_02770	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_02775	COG2814	Major facilitator Superfamily
B0E33_02795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0E33_02825	COG3811	Belongs to the UPF0386 family
B0E33_02830	COG0789	Transcriptional regulator
B0E33_02870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0E33_02870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0E33_02875	COG1132	(ABC) transporter
B0E33_02885	COG0438	transferase activity, transferring glycosyl groups
B0E33_02890	COG0438	transferase activity, transferring glycosyl groups
B0E33_02910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0E33_02915	COG0456	acetyltransferase
B0E33_02925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0E33_02930	COG0346	lactoylglutathione lyase activity
B0E33_02955	COG0583	DNA-binding transcription factor activity
B0E33_02965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0E33_02970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_02975	COG0601	transmembrane transport
B0E33_02985	COG4172	Belongs to the ABC transporter superfamily
B0E33_02995	COG0494	nUDIX hydrolase
B0E33_03000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B0E33_03010	COG0308	aminopeptidase N
B0E33_03015	COG2202	Pas domain
B0E33_03015	COG2205	protein histidine kinase activity
B0E33_03025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B0E33_03030	COG5002	protein histidine kinase activity
B0E33_03040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B0E33_03060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B0E33_03075	COG3088	subunit of a heme lyase
B0E33_03080	COG1138	Cytochrome C-type biogenesis protein
B0E33_03085	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B0E33_03090	COG4235	cytochrome complex assembly
B0E33_03105	COG2205	protein histidine kinase activity
B0E33_03110	COG0745	RESPONSE REGULATOR receiver
B0E33_03120	COG0438	transferase activity, transferring glycosyl groups
B0E33_03125	COG0561	phosphatase activity
B0E33_03145	COG1609	Transcriptional regulator
B0E33_03160	COG1073	alpha beta
B0E33_03180	COG2200	EAL domain
B0E33_03195	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_03205	COG0432	Pfam Uncharacterised protein family UPF0047
B0E33_03210	COG1819	glycosyl
B0E33_03225	COG0069	glutamate synthase activity
B0E33_03235	COG1132	(ABC) transporter
B0E33_03245	COG3300	MHYT domain
B0E33_03245	COG5001	Diguanylate cyclase
B0E33_03255	COG0251	oxidation-reduction process
B0E33_03280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0E33_03300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_03300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B0E33_03315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B0E33_03320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_03330	COG0175	sulfate reduction
B0E33_03415	COG3210	domain, Protein
B0E33_03440	COG1609	Transcriptional regulator
B0E33_03450	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_03465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0E33_03475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0E33_03480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0E33_03485	COG1121	(ABC) transporter
B0E33_03495	COG0840	transmembrane signaling receptor activity
B0E33_03505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0E33_03535	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B0E33_03590	COG0583	DNA-binding transcription factor activity
B0E33_03610	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_03615	COG1272	protein, Hemolysin III
B0E33_03620	COG1388	LysM domain
B0E33_03620	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_03630	COG2188	Transcriptional regulator
B0E33_03635	COG4172	Belongs to the ABC transporter superfamily
B0E33_03640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_03645	COG0601	transmembrane transport
B0E33_03650	COG4166	transmembrane transport
B0E33_03675	COG1396	sequence-specific DNA binding
B0E33_03680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B0E33_03705	COG1595	DNA-templated transcription, initiation
B0E33_03715	COG1187	pseudouridine synthase activity
B0E33_03720	COG2813	Specifically methylates the guanine in position
B0E33_03740	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0E33_03745	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B0E33_03795	COG1131	(ABC) transporter
B0E33_03800	COG0842	Transport permease protein
B0E33_03805	COG0697	spore germination
B0E33_03815	COG3639	organic phosphonate transmembrane transporter activity
B0E33_03835	COG4191	Histidine kinase
B0E33_03835	COG0784	Response regulator, receiver
B0E33_03845	COG0850	regulation of cytokinetic process
B0E33_03855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B0E33_03865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B0E33_03885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_03910	COG3395	kinase activity
B0E33_03915	COG0235	Class ii aldolase
B0E33_03925	COG1609	Transcriptional regulator
B0E33_03930	COG1129	ABC transporter
B0E33_03935	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_03940	COG1879	ABC-type sugar transport system periplasmic component
B0E33_03950	COG0673	inositol 2-dehydrogenase activity
B0E33_03955	COG1879	ABC-type sugar transport system periplasmic component
B0E33_03960	COG1129	ABC transporter
B0E33_03965	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_03970	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_03975	COG2186	Transcriptional regulator
B0E33_04000	COG4214	carbohydrate transport
B0E33_04010	COG4213	ABC transporter substrate-binding protein
B0E33_04025	COG0737	Belongs to the 5'-nucleotidase family
B0E33_04030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B0E33_04035	COG0424	maF-like protein
B0E33_04040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B0E33_04045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0E33_04055	COG5328	Belongs to the UPF0262 family
B0E33_04080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B0E33_04120	COG2304	oxidoreductase activity
B0E33_04140	COG0714	Associated with various cellular activities
B0E33_04155	COG4191	Histidine kinase
B0E33_04160	COG3119	arylsulfatase activity
B0E33_04200	COG0384	phenazine biosynthesis protein PhzF
B0E33_04205	COG0583	DNA-binding transcription factor activity
B0E33_04220	COG0745	RESPONSE REGULATOR receiver
B0E33_04225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_04225	COG2205	protein histidine kinase activity
B0E33_04245	COG0411	ABC transporter
B0E33_04250	COG0410	ABC transporter
B0E33_04280	COG0438	transferase activity, transferring glycosyl groups
B0E33_04285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B0E33_04290	COG2089	acid synthase
B0E33_04310	COG0443	Heat shock 70 kDa protein
B0E33_04325	COG2208	phosphoserine phosphatase activity
B0E33_04375	COG2875	Belongs to the precorrin methyltransferase family
B0E33_04380	COG2226	methyltransferase
B0E33_04385	COG1797	cobyrinic acid a,c-diamide synthase activity
B0E33_04395	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B0E33_04415	COG0438	transferase activity, transferring glycosyl groups
B0E33_04420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B0E33_04465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B0E33_04475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0E33_04490	COG0438	transferase activity, transferring glycosyl groups
B0E33_04505	COG2943	transferase activity, transferring hexosyl groups
B0E33_04510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0E33_04515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B0E33_04520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B0E33_04525	COG1137	ATPase activity
B0E33_04540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B0E33_04565	COG0411	ABC transporter
B0E33_04590	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_04610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_04630	COG1968	undecaprenyl-diphosphatase activity
B0E33_04640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B0E33_04650	COG3383	formate dehydrogenase (NAD+) activity
B0E33_04660	COG0494	nUDIX hydrolase
B0E33_04670	COG0793	Belongs to the peptidase S41A family
B0E33_04685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B0E33_04690	COG0799	negative regulation of ribosome biogenesis
B0E33_04695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B0E33_04700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B0E33_04710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B0E33_04730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B0E33_04735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B0E33_04735	COG3743	rRNA binding
B0E33_04750	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_04775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0E33_04785	COG0583	DNA-binding transcription factor activity
B0E33_04830	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0E33_04845	COG0022	dehydrogenase e1 component
B0E33_04850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B0E33_04855	COG0006	proline dipeptidase activity
B0E33_04865	COG1653	transport
B0E33_04870	COG1879	ABC-type sugar transport system periplasmic component
B0E33_04880	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_04885	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_04890	COG1129	ABC transporter
B0E33_04910	COG2186	Transcriptional regulator
B0E33_04915	COG0745	RESPONSE REGULATOR receiver
B0E33_04915	COG3706	GGDEF domain
B0E33_04920	COG5002	protein histidine kinase activity
B0E33_04920	COG2198	Histidine kinase
B0E33_04920	COG0784	Response regulator, receiver
B0E33_04940	COG0411	ABC transporter
B0E33_04945	COG0410	ABC transporter
B0E33_04950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0E33_04955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B0E33_04965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B0E33_04975	COG0745	RESPONSE REGULATOR receiver
B0E33_04985	COG0500	methyltransferase
B0E33_04995	COG2217	Heavy metal translocating P-type atpase
B0E33_05010	COG2010	Cytochrome c
B0E33_05025	COG3278	Belongs to the heme-copper respiratory oxidase family
B0E33_05030	COG0697	spore germination
B0E33_05055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B0E33_05070	COG4566	intracellular signal transduction
B0E33_05075	COG4191	Histidine kinase
B0E33_05080	COG0436	Aminotransferase
B0E33_05085	COG2205	protein histidine kinase activity
B0E33_05085	COG0784	Response regulator, receiver
B0E33_05085	COG2198	Histidine kinase
B0E33_05090	COG5001	Diguanylate cyclase
B0E33_05110	COG1793	dna ligase
B0E33_05130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B0E33_05130	COG1793	dna ligase
B0E33_05140	COG1201	RNA secondary structure unwinding
B0E33_05160	COG0628	permease
B0E33_05170	COG0730	response to heat
B0E33_05180	COG0789	Transcriptional regulator
B0E33_05185	COG1960	acyl-CoA dehydrogenase activity
B0E33_05195	COG0183	Belongs to the thiolase family
B0E33_05205	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0E33_05205	COG1024	Enoyl-CoA hydratase
B0E33_05225	COG0123	including yeast histone deacetylase and acetoin utilization protein
B0E33_05230	COG0534	Mate efflux family protein
B0E33_05235	COG0167	dihydroorotate dehydrogenase activity
B0E33_05260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B0E33_05265	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B0E33_05285	COG2967	ApaG domain
B0E33_05290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B0E33_05300	COG0717	Belongs to the dCTP deaminase family
B0E33_05305	COG1739	Uncharacterized protein family UPF0029
B0E33_05345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B0E33_05350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B0E33_05355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B0E33_05365	COG0745	RESPONSE REGULATOR receiver
B0E33_05370	COG0704	Plays a role in the regulation of phosphate uptake
B0E33_05375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B0E33_05385	COG0573	inorganic phosphate transmembrane transporter activity
B0E33_05400	COG5002	protein histidine kinase activity
B0E33_05415	COG1660	Displays ATPase and GTPase activities
B0E33_05425	COG0598	Magnesium transport protein CorA
B0E33_05440	COG0484	heat shock protein binding
B0E33_05465	COG0456	acetyltransferase
B0E33_05475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_05490	COG0583	DNA-binding transcription factor activity
B0E33_05505	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_05510	COG5001	Diguanylate cyclase
B0E33_05510	COG3300	MHYT domain
B0E33_05515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B0E33_05535	COG0668	transmembrane transport
B0E33_05545	COG1733	regulation of RNA biosynthetic process
B0E33_05555	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_05560	COG1024	Enoyl-CoA hydratase
B0E33_05565	COG1960	acyl-CoA dehydrogenase activity
B0E33_05570	COG0009	L-threonylcarbamoyladenylate synthase
B0E33_05575	COG0123	including yeast histone deacetylase and acetoin utilization protein
B0E33_05580	COG1722	exodeoxyribonuclease VII activity
B0E33_05590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B0E33_05610	COG1999	signal sequence binding
B0E33_05625	COG2226	methyltransferase
B0E33_05630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B0E33_05630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B0E33_05645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B0E33_05670	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0E33_05685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B0E33_05700	COG2135	peptidase activity
B0E33_05710	COG0494	nUDIX hydrolase
B0E33_05750	COG3119	arylsulfatase activity
B0E33_05800	COG2226	methyltransferase
B0E33_05805	COG2909	trisaccharide binding
B0E33_05820	COG0251	oxidation-reduction process
B0E33_05840	COG3246	L-lysine catabolic process to acetate
B0E33_05845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0E33_05850	COG3842	ATPase activity
B0E33_05865	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_05870	COG0583	DNA-binding transcription factor activity
B0E33_05885	COG4106	trans-aconitate 2-methyltransferase activity
B0E33_05900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B0E33_05910	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B0E33_05935	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_05980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B0E33_05985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B0E33_06000	COG0751	glycine-tRNA ligase activity
B0E33_06005	COG3300	MHYT domain
B0E33_06005	COG5001	Diguanylate cyclase
B0E33_06010	COG0786	glutamate:sodium symporter activity
B0E33_06020	COG1704	LemA family
B0E33_06030	COG0752	glycyl-tRNA synthetase alpha subunit
B0E33_06055	COG1573	uracil-dna glycosylase
B0E33_06070	COG0513	Belongs to the DEAD box helicase family
B0E33_06075	COG2133	pyrroloquinoline quinone binding
B0E33_06080	COG0287	Prephenate dehydrogenase
B0E33_06080	COG1605	Chorismate mutase
B0E33_06085	COG0281	malic enzyme
B0E33_06085	COG0280	phosphate acetyltransferase
B0E33_06095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_06100	COG0521	Mo-molybdopterin cofactor biosynthetic process
B0E33_06120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B0E33_06125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B0E33_06130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B0E33_06135	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B0E33_06140	COG0356	it plays a direct role in the translocation of protons across the membrane
B0E33_06150	COG1196	nuclear chromosome segregation
B0E33_06165	COG1194	a g-specific adenine glycosylase
B0E33_06180	COG0673	inositol 2-dehydrogenase activity
B0E33_06185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B0E33_06195	COG0765	amino acid transport
B0E33_06205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B0E33_06210	COG3300	MHYT domain
B0E33_06210	COG5001	Diguanylate cyclase
B0E33_06220	COG3284	Transcriptional regulator
B0E33_06220	COG3284	Transcriptional regulator
B0E33_06225	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_06235	COG1733	regulation of RNA biosynthetic process
B0E33_06250	COG1942	4-Oxalocrotonate Tautomerase
B0E33_06260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B0E33_06270	COG1846	Transcriptional regulator
B0E33_06295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B0E33_06300	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B0E33_06310	COG0509	glycine decarboxylation via glycine cleavage system
B0E33_06315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0E33_06325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B0E33_06330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B0E33_06335	COG0328	RNA-DNA hybrid ribonuclease activity
B0E33_06340	COG1597	lipid kinase activity
B0E33_06350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0E33_06355	COG0612	Peptidase, M16
B0E33_06365	COG1678	Uncharacterized ACR, COG1678
B0E33_06375	COG0678	peroxiredoxin activity
B0E33_06375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B0E33_06380	COG3346	SURF1 family
B0E33_06400	COG0109	protoheme IX farnesyltransferase activity
B0E33_06405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B0E33_06410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B0E33_06435	COG0312	modulator of DNA gyrase
B0E33_06445	COG1663	tetraacyldisaccharide 4'-kinase activity
B0E33_06450	COG1519	Transferase
B0E33_06465	COG0483	inositol monophosphate 1-phosphatase activity
B0E33_06470	COG0312	modulator of DNA gyrase
B0E33_06485	COG0151	Belongs to the GarS family
B0E33_06490	COG0596	Alpha beta hydrolase
B0E33_06495	COG5001	Diguanylate cyclase
B0E33_06500	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0E33_06515	COG0742	ribosomal rna small subunit methyltransferase
B0E33_06520	COG1187	pseudouridine synthase activity
B0E33_06525	COG0590	tRNA wobble adenosine to inosine editing
B0E33_06550	COG1309	transcriptional regulator
B0E33_06570	COG0745	RESPONSE REGULATOR receiver
B0E33_06575	COG2030	dehydratase
B0E33_06580	COG0196	riboflavin kinase activity
B0E33_06600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B0E33_06610	COG0612	Peptidase, M16
B0E33_06615	COG0612	Peptidase, M16
B0E33_06630	COG2204	response regulator
B0E33_06640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B0E33_06645	COG0459	protein refolding
B0E33_06650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B0E33_06665	COG0625	glutathione transferase activity
B0E33_06670	COG2900	Belongs to the SlyX family
B0E33_06680	COG0577	efflux transmembrane transporter activity
B0E33_06680	COG1136	(ABC) transporter
B0E33_06685	COG1136	(ABC) transporter
B0E33_06700	COG1607	acyl-coa hydrolase
B0E33_06715	COG1959	2 iron, 2 sulfur cluster binding
B0E33_06740	COG0124	histidyl-tRNA synthetase
B0E33_06745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B0E33_06750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B0E33_06755	COG2818	Glycosylase
B0E33_06770	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_06775	COG0038	chloride channel
B0E33_06780	COG0247	lactate metabolic process
B0E33_06795	COG0277	FAD linked oxidase domain protein
B0E33_06800	COG0277	FAD linked oxidase domain protein
B0E33_06805	COG0583	DNA-binding transcription factor activity
B0E33_06820	COG2186	Transcriptional regulator
B0E33_06825	COG1304	FMN binding
B0E33_06850	COG0583	DNA-binding transcription factor activity
B0E33_06855	COG0583	DNA-binding transcription factor activity
B0E33_06885	COG1570	exodeoxyribonuclease VII activity
B0E33_06915	COG4191	Histidine kinase
B0E33_06925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0E33_06925	COG0045	succinate-CoA ligase (ADP-forming) activity
B0E33_06925	COG1042	CoA-binding domain protein
B0E33_06935	COG0583	DNA-binding transcription factor activity
B0E33_06950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_06955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_06985	COG1511	domain protein
B0E33_06985	COG3264	Mechanosensitive ion channel
B0E33_06990	COG2351	hydroxyisourate hydrolase activity
B0E33_07000	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B0E33_07010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B0E33_07035	COG1414	Transcriptional regulator
B0E33_07040	COG3257	ureidoglycine aminohydrolase activity
B0E33_07050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_07065	COG0028	Belongs to the TPP enzyme family
B0E33_07090	COG0730	response to heat
B0E33_07100	COG1741	Belongs to the pirin family
B0E33_07105	COG2388	GCN5-related N-acetyl-transferase
B0E33_07125	COG2169	Transcriptional regulator
B0E33_07125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0E33_07165	COG1840	ABC-type Fe3 transport system, periplasmic component
B0E33_07210	COG1177	transmembrane transport
B0E33_07215	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_07220	COG3842	ATPase activity
B0E33_07230	COG0174	glutamine synthetase
B0E33_07240	COG0174	glutamine synthetase
B0E33_07255	COG3795	YCII-related domain
B0E33_07260	COG4941	Belongs to the sigma-70 factor family
B0E33_07280	COG3706	GGDEF domain
B0E33_07285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0E33_07295	COG0175	sulfate reduction
B0E33_07300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B0E33_07310	COG1648	precorrin-2 dehydrogenase activity
B0E33_07310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0E33_07320	COG0183	Belongs to the thiolase family
B0E33_07325	COG0366	Alpha amylase catalytic
B0E33_07330	COG0463	Glycosyl transferase, family 2
B0E33_07340	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_07350	COG1309	transcriptional regulator
B0E33_07365	COG0517	IMP dehydrogenase activity
B0E33_07365	COG4175	Glycine betaine
B0E33_07370	COG1278	Cold shock
B0E33_07385	COG1671	Belongs to the UPF0178 family
B0E33_07405	COG1959	2 iron, 2 sulfur cluster binding
B0E33_07410	COG1609	Transcriptional regulator
B0E33_07415	COG2081	HI0933 family
B0E33_07420	COG0683	leucine binding
B0E33_07430	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_07435	COG0410	ABC transporter
B0E33_07445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B0E33_07450	COG5001	Diguanylate cyclase
B0E33_07450	COG3300	MHYT domain
B0E33_07460	COG1760	l-serine dehydratase
B0E33_07470	COG1802	Transcriptional regulator
B0E33_07475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B0E33_07480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0E33_07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0E33_07510	COG1278	Cold shock
B0E33_07540	COG3852	Histidine kinase
B0E33_07550	COG0398	Pfam SNARE associated Golgi protein
B0E33_07555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B0E33_07560	COG0594	ribonuclease P activity
B0E33_07565	COG0706	membrane insertase activity
B0E33_07590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B0E33_07600	COG3739	integral membrane protein
B0E33_07615	COG0183	Belongs to the thiolase family
B0E33_07620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B0E33_07630	COG1414	Transcriptional regulator
B0E33_07635	COG1090	epimerase
B0E33_07655	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_07660	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_07670	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_07675	COG1129	ABC transporter
B0E33_07685	COG2186	Transcriptional regulator
B0E33_07690	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_07695	COG4251	negative regulation of phosphorylation
B0E33_07695	COG5001	Diguanylate cyclase
B0E33_07695	COG2203	Gaf domain
B0E33_07695	COG3706	GGDEF domain
B0E33_07705	COG2171	N-acyltransferase activity
B0E33_07715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0E33_07725	COG0668	transmembrane transport
B0E33_07735	COG0101	tRNA pseudouridine synthase activity
B0E33_07750	COG2095	MarC family integral membrane protein
B0E33_07755	COG0242	peptide deformylase activity
B0E33_07780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B0E33_07815	COG4964	Belongs to the GSP D family
B0E33_07855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B0E33_07880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B0E33_07890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_07895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B0E33_07910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B0E33_07915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B0E33_07920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B0E33_07925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B0E33_07930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B0E33_07935	COG0295	cytidine deaminase activity
B0E33_07980	COG1803	Methylglyoxal synthase
B0E33_07985	COG0837	glucose binding
B0E33_07990	COG1643	Atp-dependent helicase
B0E33_08000	COG1522	sequence-specific DNA binding
B0E33_08005	COG4134	Bacterial extracellular solute-binding protein
B0E33_08010	COG4135	transport system, permease component
B0E33_08015	COG4136	ATPase activity
B0E33_08030	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_08035	COG0840	transmembrane signaling receptor activity
B0E33_08040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B0E33_08045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B0E33_08055	COG0450	alkyl hydroperoxide reductase
B0E33_08065	COG1278	Cold shock
B0E33_08075	COG1032	radical SAM domain protein
B0E33_08085	COG0400	carboxylic ester hydrolase activity
B0E33_08095	COG1363	Peptidase, m42
B0E33_08110	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
B0E33_08120	COG0481	GTPase activity
B0E33_08125	COG2824	Alkylphosphonate utilization operon protein PhnA
B0E33_08130	COG0583	DNA-binding transcription factor activity
B0E33_08135	COG1942	4-Oxalocrotonate Tautomerase
B0E33_08140	COG0583	DNA-binding transcription factor activity
B0E33_08145	COG1295	ribonuclease BN
B0E33_08150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B0E33_08160	COG0072	phenylalanine-tRNA ligase activity
B0E33_08160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0E33_08200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0E33_08245	COG0811	peptide transport
B0E33_08250	COG0848	biopolymer transport protein
B0E33_08265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0E33_08265	COG2169	Transcriptional regulator
B0E33_08270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B0E33_08275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B0E33_08355	COG2391	methyltransferase activity
B0E33_08395	COG1595	DNA-templated transcription, initiation
B0E33_08410	COG4335	DNA alkylation repair
B0E33_08420	COG0395	ABC-type sugar transport system, permease component
B0E33_08430	COG1653	transport
B0E33_08445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B0E33_08455	COG0587	DNA-directed DNA polymerase activity
B0E33_08480	COG0667	Aldo Keto reductase
B0E33_08540	COG0583	DNA-binding transcription factor activity
B0E33_08545	COG2814	Major facilitator Superfamily
B0E33_08550	COG0667	Aldo Keto reductase
B0E33_08565	COG2807	transmembrane transport
B0E33_08585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0E33_08590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0E33_08600	COG0754	glutathionylspermidine amidase activity
B0E33_08605	COG1842	Phage shock protein A
B0E33_08610	COG3789	protein conserved in bacteria
B0E33_08625	COG3766	membrane
B0E33_08635	COG0386	Belongs to the glutathione peroxidase family
B0E33_08640	COG3443	Belongs to the bacterial solute-binding protein 9 family
B0E33_08650	COG0583	DNA-binding transcription factor activity
B0E33_08655	COG0697	spore germination
B0E33_08660	COG0823	Involved in the tonB-independent uptake of proteins
B0E33_08670	COG0584	glycerophosphoryl diester phosphodiesterase
B0E33_08675	COG3842	ATPase activity
B0E33_08680	COG3833	ABC-type maltose transport systems, permease component
B0E33_08740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B0E33_08750	COG0539	negative regulation of cytoplasmic translation
B0E33_08780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B0E33_08785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_08800	COG1047	Peptidyl-prolyl cis-trans
B0E33_08805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_08825	COG0616	signal peptide processing
B0E33_08830	COG0776	regulation of translation
B0E33_08850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B0E33_08860	COG1074	ATP-dependent DNA helicase activity
B0E33_08865	COG2887	Belongs to the helicase family. UvrD subfamily
B0E33_08870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B0E33_08875	COG0802	atpase or kinase
B0E33_08880	COG2205	protein histidine kinase activity
B0E33_08890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B0E33_08895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0E33_08900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0E33_08900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B0E33_08910	COG2205	protein histidine kinase activity
B0E33_08915	COG0745	RESPONSE REGULATOR receiver
B0E33_08920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B0E33_08930	COG1280	lysine exporter protein (LysE YggA)
B0E33_08935	COG3608	succinylglutamate desuccinylase aspartoacylase
B0E33_08935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B0E33_08940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B0E33_08950	COG5001	Diguanylate cyclase
B0E33_08950	COG3300	MHYT domain
B0E33_08955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B0E33_08960	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B0E33_08965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B0E33_08970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B0E33_08975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B0E33_08985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B0E33_08990	COG4974	Belongs to the 'phage' integrase family
B0E33_09020	COG0789	Transcriptional regulator
B0E33_09035	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_09045	COG1280	lysine exporter protein (LysE YggA)
B0E33_09055	COG0567	Dehydrogenase, E1 component
B0E33_09060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B0E33_09065	COG0045	succinate-CoA ligase (ADP-forming) activity
B0E33_09070	COG0039	L-malate dehydrogenase activity
B0E33_09075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B0E33_09080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B0E33_09110	COG0514	ATP-dependent DNA helicase (RecQ)
B0E33_09120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0E33_09135	COG4452	Inner membrane protein CreD
B0E33_09145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0E33_09175	COG2066	Belongs to the glutaminase family
B0E33_09190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B0E33_09195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B0E33_09200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B0E33_09230	COG2816	NAD+ diphosphatase activity
B0E33_09245	COG0659	secondary active sulfate transmembrane transporter activity
B0E33_09260	COG4172	Belongs to the ABC transporter superfamily
B0E33_09270	COG4174	ABC transporter (Permease)
B0E33_09275	COG4166	transmembrane transport
B0E33_09280	COG4166	transmembrane transport
B0E33_09290	COG3474	cytochrome
B0E33_09295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B0E33_09300	COG1605	Chorismate mutase
B0E33_09300	COG0077	Prephenate dehydratase
B0E33_09305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_09310	COG0154	amidase activity
B0E33_09325	COG4221	oxidoreductase activity
B0E33_09340	COG2133	pyrroloquinoline quinone binding
B0E33_09365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0E33_09370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_09380	COG2267	carboxylic ester hydrolase activity
B0E33_09395	COG4566	intracellular signal transduction
B0E33_09405	COG4191	Histidine kinase
B0E33_09420	COG2205	protein histidine kinase activity
B0E33_09425	COG0745	RESPONSE REGULATOR receiver
B0E33_09455	COG2197	response regulator
B0E33_09460	COG1704	LemA family
B0E33_09485	COG2304	oxidoreductase activity
B0E33_09495	COG0588	phosphoglycerate mutase activity
B0E33_09500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B0E33_09505	COG5001	Diguanylate cyclase
B0E33_09505	COG3300	MHYT domain
B0E33_09515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B0E33_09520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B0E33_09525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B0E33_09530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B0E33_09545	COG0779	Required for maturation of 30S ribosomal subunits
B0E33_09550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B0E33_09555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B0E33_09560	COG1396	sequence-specific DNA binding
B0E33_09565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B0E33_09570	COG1253	flavin adenine dinucleotide binding
B0E33_09575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B0E33_09580	COG1702	phosphate starvation-inducible protein PhoH
B0E33_09585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B0E33_09620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B0E33_09630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B0E33_09640	COG3963	phosphatidate phosphatase activity
B0E33_09645	COG0484	heat shock protein binding
B0E33_09650	COG0443	Heat shock 70 kDa protein
B0E33_09660	COG3145	DNA-N1-methyladenine dioxygenase activity
B0E33_09680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B0E33_09685	COG2226	methyltransferase
B0E33_09690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B0E33_09695	COG1024	Enoyl-CoA hydratase
B0E33_09700	COG0268	Binds directly to 16S ribosomal RNA
B0E33_09710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B0E33_09715	COG0592	DNA-directed DNA polymerase activity
B0E33_09725	COG0187	DNA topoisomerase II activity
B0E33_09735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B0E33_09740	COG3046	protein related to deoxyribodipyrimidine photolyase
B0E33_09765	COG3246	L-lysine catabolic process to acetate
B0E33_09780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_09800	COG1960	acyl-CoA dehydrogenase activity
B0E33_09805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0E33_09815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B0E33_09820	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_09825	COG1024	Enoyl-CoA hydratase
B0E33_09825	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0E33_09830	COG0183	Belongs to the thiolase family
B0E33_09845	COG2188	Transcriptional regulator
B0E33_09850	COG1454	alcohol dehydrogenase
B0E33_09865	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_09875	COG0411	ABC transporter
B0E33_09910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0E33_09955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B0E33_10045	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_10050	COG0683	leucine binding
B0E33_10055	COG2268	Band 7 protein
B0E33_10060	COG0583	DNA-binding transcription factor activity
B0E33_10095	COG2948	multi-organism process
B0E33_10110	COG3846	protein secretion by the type IV secretion system
B0E33_10125	COG3451	type IV secretory pathway VirB4
B0E33_10140	COG4962	Type ii secretion system protein e
B0E33_10145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B0E33_10170	COG0741	lytic transglycosylase activity
B0E33_10190	COG1192	Involved in chromosome partitioning
B0E33_10280	COG0629	single-stranded DNA binding
B0E33_10320	COG4227	nucleotidyltransferase activity
B0E33_10330	COG4221	oxidoreductase activity
B0E33_10335	COG1309	transcriptional regulator
B0E33_10340	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_10360	COG1309	transcriptional regulator
B0E33_10370	COG0596	Alpha beta hydrolase
B0E33_10375	COG2084	Dehydrogenase
B0E33_10380	COG0129	dihydroxy-acid dehydratase activity
B0E33_10390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_10400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_10460	COG0515	serine threonine protein kinase
B0E33_10460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0E33_10470	COG4974	Belongs to the 'phage' integrase family
B0E33_10480	COG0019	diaminopimelate decarboxylase activity
B0E33_10485	COG4172	Belongs to the ABC transporter superfamily
B0E33_10505	COG5598	trimethylamine methyltransferase
B0E33_10510	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_10515	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_10520	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_10525	COG0583	DNA-binding transcription factor activity
B0E33_10535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_10540	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B0E33_10565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_10610	COG0840	transmembrane signaling receptor activity
B0E33_10625	COG2208	phosphoserine phosphatase activity
B0E33_10635	COG1366	Belongs to the anti-sigma-factor antagonist family
B0E33_10640	COG0631	protein serine/threonine phosphatase activity
B0E33_10650	COG2815	serine threonine protein kinase
B0E33_10650	COG0515	serine threonine protein kinase
B0E33_10670	COG1177	transmembrane transport
B0E33_10675	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_10685	COG3842	ATPase activity
B0E33_10690	COG0683	leucine binding
B0E33_10725	COG1720	tRNA m6t6A37 methyltransferase activity
B0E33_10730	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0E33_10730	COG1024	Enoyl-CoA hydratase
B0E33_10745	COG1960	acyl-CoA dehydrogenase activity
B0E33_10765	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_10775	COG0438	transferase activity, transferring glycosyl groups
B0E33_10810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_10835	COG0583	DNA-binding transcription factor activity
B0E33_10840	COG1960	acyl-CoA dehydrogenase activity
B0E33_10855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B0E33_10870	COG0671	phosphoesterase, PA-phosphatase related
B0E33_10910	COG2814	Major facilitator Superfamily
B0E33_10920	COG2115	Belongs to the xylose isomerase family
B0E33_10925	COG1070	Carbohydrate kinase
B0E33_10935	COG4214	carbohydrate transport
B0E33_10940	COG4213	ABC transporter substrate-binding protein
B0E33_10945	COG1940	carbohydrate kinase activity
B0E33_10945	COG1846	Transcriptional regulator
B0E33_10960	COG0251	oxidation-reduction process
B0E33_10965	COG2249	NAD(P)H dehydrogenase (quinone) activity
B0E33_10975	COG0402	S-adenosylhomocysteine deaminase activity
B0E33_10985	COG1116	anion transmembrane transporter activity
B0E33_10990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_11020	COG5001	Diguanylate cyclase
B0E33_11020	COG3300	MHYT domain
B0E33_11030	COG0778	Nitroreductase
B0E33_11035	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
B0E33_11055	COG1269	ATP hydrolysis coupled proton transport
B0E33_11065	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
B0E33_11080	COG3300	MHYT domain
B0E33_11080	COG5001	Diguanylate cyclase
B0E33_11090	COG1609	Transcriptional regulator
B0E33_11105	COG0395	ABC-type sugar transport system, permease component
B0E33_11110	COG3842	ATPase activity
B0E33_11125	COG0667	Aldo Keto reductase
B0E33_11130	COG3507	Belongs to the glycosyl hydrolase 43 family
B0E33_11145	COG1653	transport
B0E33_11155	COG0395	ABC-type sugar transport system, permease component
B0E33_11165	COG0837	glucose binding
B0E33_11170	COG0583	DNA-binding transcription factor activity
B0E33_11180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B0E33_11185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B0E33_11190	COG3485	protocatechuate 3,4-dioxygenase
B0E33_11195	COG3485	protocatechuate 3,4-dioxygenase
B0E33_11200	COG3246	L-lysine catabolic process to acetate
B0E33_11205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B0E33_11210	COG0583	DNA-binding transcription factor activity
B0E33_11220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B0E33_11235	COG0402	S-adenosylhomocysteine deaminase activity
B0E33_11240	COG0625	glutathione transferase activity
B0E33_11265	COG0747	negative chemotaxis
B0E33_11270	COG0601	transmembrane transport
B0E33_11300	COG4608	Belongs to the ABC transporter superfamily
B0E33_11305	COG0747	negative chemotaxis
B0E33_11310	COG0601	transmembrane transport
B0E33_11320	COG0405	Gamma-glutamyltransferase
B0E33_11330	COG1177	transmembrane transport
B0E33_11335	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_11340	COG3842	ATPase activity
B0E33_11345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B0E33_11405	COG0200	Binds to the 23S rRNA
B0E33_11435	COG3550	peptidyl-serine autophosphorylation
B0E33_11535	COG0183	Belongs to the thiolase family
B0E33_11540	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_11545	COG1268	BioY protein
B0E33_11550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B0E33_11555	COG1122	ATPase activity
B0E33_11570	COG0583	DNA-binding transcription factor activity
B0E33_11585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0E33_11595	COG1393	Belongs to the ArsC family
B0E33_11610	COG0747	negative chemotaxis
B0E33_11620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_11630	COG2217	Heavy metal translocating P-type atpase
B0E33_11635	COG0129	dihydroxy-acid dehydratase activity
B0E33_11645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_11655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_11660	COG1595	DNA-templated transcription, initiation
B0E33_11675	COG4191	Histidine kinase
B0E33_11685	COG4149	molybdate abc transporter
B0E33_11715	COG0456	acetyltransferase
B0E33_11720	COG1162	GTPase activity
B0E33_11725	COG0372	Belongs to the citrate synthase family
B0E33_11730	COG0372	Belongs to the citrate synthase family
B0E33_11735	COG0583	DNA-binding transcription factor activity
B0E33_11750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_11765	COG1522	sequence-specific DNA binding
B0E33_11780	COG0189	ligase activity
B0E33_11785	COG0792	nuclease activity
B0E33_11790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B0E33_11805	COG3384	dioxygenase
B0E33_11810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B0E33_11810	COG2885	chlorophyll binding
B0E33_11820	COG0756	dUTP diphosphatase activity
B0E33_11825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0E33_11830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B0E33_11835	COG0010	Belongs to the arginase family
B0E33_11845	COG0393	Putative heavy-metal-binding
B0E33_11850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B0E33_11865	COG3284	Transcriptional regulator
B0E33_11875	COG1858	cytochrome C peroxidase
B0E33_11880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B0E33_11890	COG0606	chelatase, subunit chli
B0E33_11930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B0E33_11930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B0E33_11950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B0E33_11965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B0E33_11975	COG0180	Tryptophanyl-tRNA synthetase
B0E33_11990	COG5002	protein histidine kinase activity
B0E33_11990	COG0784	Response regulator, receiver
B0E33_11990	COG2205	protein histidine kinase activity
B0E33_12000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0E33_12010	COG0583	DNA-binding transcription factor activity
B0E33_12040	COG0052	Belongs to the universal ribosomal protein uS2 family
B0E33_12045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B0E33_12050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B0E33_12065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B0E33_12070	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B0E33_12080	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B0E33_12090	COG0840	transmembrane signaling receptor activity
B0E33_12095	COG1309	transcriptional regulator
B0E33_12100	COG0251	oxidation-reduction process
B0E33_12105	COG0596	Alpha beta hydrolase
B0E33_12110	COG1072	(Pantothenic acid kinase))
B0E33_12115	COG0140	phosphoribosyl-ATP diphosphatase activity
B0E33_12120	COG0107	imidazoleglycerol-phosphate synthase activity
B0E33_12125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B0E33_12135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B0E33_12145	COG0131	Imidazoleglycerol-phosphate dehydratase
B0E33_12155	COG0284	orotidine-5'-phosphate decarboxylase activity
B0E33_12180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0E33_12190	COG0285	dihydrofolate synthase activity
B0E33_12195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B0E33_12200	COG0159	tryptophan synthase activity
B0E33_12220	COG0133	tryptophan synthase activity
B0E33_12225	COG0135	phosphoribosylanthranilate isomerase activity
B0E33_12235	COG0281	malic enzyme
B0E33_12235	COG0280	phosphate acetyltransferase
B0E33_12240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B0E33_12255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B0E33_12270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B0E33_12280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0E33_12300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B0E33_12305	COG0237	dephospho-CoA kinase activity
B0E33_12310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B0E33_12320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B0E33_12325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B0E33_12335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B0E33_12345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B0E33_12350	COG0445	tRNA wobble uridine modification
B0E33_12355	COG0357	Ribosomal RNA small subunit methyltransferase G
B0E33_12360	COG1192	Involved in chromosome partitioning
B0E33_12365	COG1475	DNA binding
B0E33_12380	COG0495	leucyl-tRNA aminoacylation
B0E33_12400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B0E33_12430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B0E33_12435	COG1605	Chorismate mutase
B0E33_12435	COG0287	Prephenate dehydrogenase
B0E33_12440	COG0228	four-way junction DNA binding
B0E33_12445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B0E33_12455	COG0336	Belongs to the RNA methyltransferase TrmD family
B0E33_12460	COG0335	large ribosomal subunit rRNA binding
B0E33_12465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B0E33_12485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0E33_12495	COG2304	oxidoreductase activity
B0E33_12505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B0E33_12510	COG0830	nickel cation binding
B0E33_12525	COG0804	urea catabolic process
B0E33_12535	COG3755	Protein conserved in bacteria
B0E33_12540	COG0832	Belongs to the urease beta subunit family
B0E33_12545	COG0831	urea catabolic process
B0E33_12550	COG0829	nickel cation binding
B0E33_12565	COG0523	cobalamin synthesis protein
B0E33_12570	COG1946	Acyl-CoA thioesterase
B0E33_12575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0E33_12580	COG0300	oxidoreductase activity
B0E33_12600	COG4520	surface antigen
B0E33_12610	COG1595	DNA-templated transcription, initiation
B0E33_12620	COG2086	electron transfer activity
B0E33_12625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B0E33_12630	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0E33_12655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0E33_12660	COG0165	Argininosuccinate lyase
B0E33_12670	COG0019	diaminopimelate decarboxylase activity
B0E33_12680	COG0745	RESPONSE REGULATOR receiver
B0E33_12685	COG0037	tRNA processing
B0E33_12685	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B0E33_12695	COG2884	Cell division ATP-binding protein ftsE
B0E33_12715	COG1953	Uracil, thiamine, allantoin
B0E33_12725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B0E33_12745	COG2301	Belongs to the HpcH HpaI aldolase family
B0E33_12755	COG3119	arylsulfatase activity
B0E33_12775	COG2249	NAD(P)H dehydrogenase (quinone) activity
B0E33_12780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0E33_12800	COG0436	Aminotransferase
B0E33_12815	COG0501	Belongs to the peptidase M48B family
B0E33_12840	COG2270	Major facilitator Superfamily
B0E33_12845	COG2902	Dehydrogenase
B0E33_12855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B0E33_12860	COG0066	3-isopropylmalate dehydratase activity
B0E33_12870	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B0E33_12880	COG0745	RESPONSE REGULATOR receiver
B0E33_12895	COG2321	neutral zinc metallopeptidase
B0E33_12900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B0E33_12905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B0E33_12910	COG0552	protein localization to endoplasmic reticulum
B0E33_12955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B0E33_12965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B0E33_12970	COG0287	Prephenate dehydrogenase
B0E33_12975	COG0142	geranyltranstransferase activity
B0E33_12980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B0E33_12985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B0E33_12990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B0E33_13000	COG2917	probably involved in intracellular septation
B0E33_13015	COG0183	Belongs to the thiolase family
B0E33_13035	COG0405	Gamma-glutamyltransferase
B0E33_13065	COG1115	amino acid carrier protein
B0E33_13070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B0E33_13085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B0E33_13100	COG0604	alcohol dehydrogenase
B0E33_13115	COG2186	Transcriptional regulator
B0E33_13135	COG4783	chaperone-mediated protein folding
B0E33_13140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B0E33_13145	COG1329	Transcriptional regulator
B0E33_13165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B0E33_13175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B0E33_13185	COG3487	Iron-regulated protein
B0E33_13235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B0E33_13240	COG3454	Phosphonate metabolism
B0E33_13245	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B0E33_13250	COG4778	phosphonate C-P lyase system protein PhnL
B0E33_13255	COG4107	phosphonate C-P lyase system protein PhnK
B0E33_13260	COG3627	carbon phosphorus lyase activity
B0E33_13265	COG0346	lactoylglutathione lyase activity
B0E33_13270	COG3626	phosphonate metabolism
B0E33_13275	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B0E33_13280	COG3624	Phosphonate C-P lyase system protein PhnG
B0E33_13285	COG2188	Transcriptional regulator
B0E33_13350	COG4555	ABC transporter
B0E33_13395	COG1802	Transcriptional regulator
B0E33_13410	COG0583	DNA-binding transcription factor activity
B0E33_13415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B0E33_13455	COG1238	metal cluster binding
B0E33_13475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B0E33_13505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_13520	COG0670	Belongs to the BI1 family
B0E33_13535	COG4181	ATPase activity
B0E33_13545	COG0667	Aldo Keto reductase
B0E33_13550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B0E33_13560	COG0438	transferase activity, transferring glycosyl groups
B0E33_13575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B0E33_13590	COG0024	Methionine aminopeptidase
B0E33_13615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B0E33_13620	COG2154	pterin-4-alpha-carbinolamine dehydratase
B0E33_13640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B0E33_13645	COG0347	Belongs to the P(II) protein family
B0E33_13650	COG0004	ammonium transporteR
B0E33_13655	COG0004	ammonium transporteR
B0E33_13660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0E33_13665	COG0395	ABC-type sugar transport system, permease component
B0E33_13675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B0E33_13690	COG1597	lipid kinase activity
B0E33_13700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B0E33_13710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0E33_13730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0E33_13740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B0E33_13745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B0E33_13750	COG4133	protoheme IX ABC transporter activity
B0E33_13780	COG0714	Associated with various cellular activities
B0E33_13800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B0E33_13815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B0E33_13820	COG0602	queuosine metabolic process
B0E33_13825	COG0720	synthase
B0E33_13830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B0E33_13865	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_13895	COG0667	Aldo Keto reductase
B0E33_13915	COG2835	tetraacyldisaccharide 4'-kinase activity
B0E33_13920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B0E33_13945	COG4413	Urea transporter
B0E33_13950	COG0673	inositol 2-dehydrogenase activity
B0E33_13970	COG0405	Gamma-glutamyltransferase
B0E33_13985	COG3012	SEC-C Motif Domain Protein
B0E33_14000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0E33_14005	COG0840	transmembrane signaling receptor activity
B0E33_14010	COG4974	Belongs to the 'phage' integrase family
B0E33_14015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B0E33_14020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B0E33_14025	COG4536	flavin adenine dinucleotide binding
B0E33_14060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B0E33_14075	COG0825	malonyl-CoA metabolic process
B0E33_14080	COG3034	peptidoglycan biosynthetic process
B0E33_14090	COG0494	nUDIX hydrolase
B0E33_14105	COG2197	response regulator
B0E33_14110	COG2030	dehydratase
B0E33_14115	COG2391	methyltransferase activity
B0E33_14130	COG1846	Transcriptional regulator
B0E33_14135	COG2814	Major facilitator Superfamily
B0E33_14145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B0E33_14150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B0E33_14185	COG0840	transmembrane signaling receptor activity
B0E33_14190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B0E33_14200	COG1595	DNA-templated transcription, initiation
B0E33_14215	COG0708	Exodeoxyribonuclease III
B0E33_14235	COG4991	sh3 domain protein
B0E33_14245	COG2226	methyltransferase
B0E33_14270	COG0288	reversible hydration of carbon dioxide
B0E33_14280	COG0235	Class ii aldolase
B0E33_14285	COG2390	Transcriptional regulator
B0E33_14290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B0E33_14300	COG1129	ABC transporter
B0E33_14305	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_14320	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B0E33_14325	COG3290	protein histidine kinase activity
B0E33_14325	COG0840	transmembrane signaling receptor activity
B0E33_14335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_14340	COG1120	ATPase activity
B0E33_14375	COG0583	DNA-binding transcription factor activity
B0E33_14380	COG0697	spore germination
B0E33_14390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B0E33_14410	COG0640	Transcriptional regulator
B0E33_14420	COG2814	Major facilitator Superfamily
B0E33_14440	COG1846	Transcriptional regulator
B0E33_14445	COG1238	metal cluster binding
B0E33_14450	COG0346	lactoylglutathione lyase activity
B0E33_14460	COG0473	3-isopropylmalate dehydrogenase activity
B0E33_14475	COG1473	amidohydrolase
B0E33_14480	COG2264	protein methyltransferase activity
B0E33_14495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B0E33_14510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B0E33_14515	COG0181	hydroxymethylbilane synthase activity
B0E33_14550	COG0745	RESPONSE REGULATOR receiver
B0E33_14560	COG1024	Enoyl-CoA hydratase
B0E33_14570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0E33_14585	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B0E33_14595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B0E33_14605	COG2326	polyphosphate kinase activity
B0E33_14630	COG0483	inositol monophosphate 1-phosphatase activity
B0E33_14635	COG3842	ATPase activity
B0E33_14645	COG1840	ABC-type Fe3 transport system, periplasmic component
B0E33_14650	COG1840	ABC-type Fe3 transport system, periplasmic component
B0E33_14655	COG0745	RESPONSE REGULATOR receiver
B0E33_14665	COG0673	inositol 2-dehydrogenase activity
B0E33_14675	COG1024	Enoyl-CoA hydratase
B0E33_14685	COG1609	Transcriptional regulator
B0E33_14705	COG3842	ATPase activity
B0E33_14735	COG1609	Transcriptional regulator
B0E33_14745	COG0546	phosphoglycolate phosphatase activity
B0E33_14750	COG1595	DNA-templated transcription, initiation
B0E33_14755	COG0655	NAD(P)H dehydrogenase (quinone) activity
B0E33_14760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B0E33_14775	COG3339	Conserved Protein
B0E33_14810	COG1285	pathogenesis
B0E33_14820	COG1295	ribonuclease BN
B0E33_14845	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0E33_14845	COG0596	Alpha beta hydrolase
B0E33_14865	COG0463	Glycosyl transferase, family 2
B0E33_14870	COG0653	protein targeting
B0E33_14875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B0E33_14880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B0E33_14885	COG0494	nUDIX hydrolase
B0E33_14900	COG1040	competence protein
B0E33_14910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0E33_14935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0E33_14940	COG0527	aspartate kinase activity
B0E33_14950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B0E33_14955	COG2890	protein-(glutamine-N5) methyltransferase activity
B0E33_14985	COG0739	heme binding
B0E33_15030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B0E33_15055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B0E33_15065	COG2801	Transposase and inactivated derivatives
B0E33_15100	COG1401	restriction endodeoxyribonuclease activity
B0E33_15105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_15105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_15115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_15125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_15135	COG0583	DNA-binding transcription factor activity
B0E33_15140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_15150	COG1177	transmembrane transport
B0E33_15155	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0E33_15160	COG3842	ATPase activity
B0E33_15165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B0E33_15175	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_15190	COG2197	response regulator
B0E33_15215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_15235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B0E33_15240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0E33_15250	COG4214	carbohydrate transport
B0E33_15265	COG1609	Transcriptional regulator
B0E33_15295	COG2378	regulation of single-species biofilm formation
B0E33_15300	COG3002	Belongs to the UPF0753 family
B0E33_15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B0E33_15320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0E33_15325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_15340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B0E33_15350	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_15360	COG1420	regulation of RNA biosynthetic process
B0E33_15375	COG0765	amino acid transport
B0E33_15380	COG1126	abc transporter atp-binding protein
B0E33_15385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_15390	COG3938	Belongs to the proline racemase family
B0E33_15395	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_15400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_15405	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_15410	COG3938	Belongs to the proline racemase family
B0E33_15415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B0E33_15420	COG0246	Mannitol dehydrogenase
B0E33_15435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_15450	COG2186	Transcriptional regulator
B0E33_15465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B0E33_15515	COG3246	L-lysine catabolic process to acetate
B0E33_15525	COG3485	protocatechuate 3,4-dioxygenase
B0E33_15530	COG0625	glutathione transferase activity
B0E33_15570	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0E33_15575	COG3971	2-oxopent-4-enoate hydratase activity
B0E33_15585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B0E33_15610	COG1414	Transcriptional regulator
B0E33_15635	COG2204	response regulator
B0E33_15640	COG3852	Histidine kinase
B0E33_15660	COG1129	ABC transporter
B0E33_15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_15670	COG2390	Transcriptional regulator
B0E33_15675	COG0667	Aldo Keto reductase
B0E33_15680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B0E33_15690	COG1070	Carbohydrate kinase
B0E33_15700	COG1396	sequence-specific DNA binding
B0E33_15700	COG3800	Transcriptional regulator
B0E33_15710	COG0583	DNA-binding transcription factor activity
B0E33_15725	COG0738	Major facilitator superfamily
B0E33_15750	COG0583	DNA-binding transcription factor activity
B0E33_15765	COG1902	pentaerythritol trinitrate reductase activity
B0E33_15785	COG3591	Belongs to the peptidase S1B family
B0E33_15785	COG1864	DNA RNA non-specific endonuclease
B0E33_15805	COG2885	chlorophyll binding
B0E33_15810	COG1609	Transcriptional regulator
B0E33_15815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B0E33_15830	COG0436	Aminotransferase
B0E33_15835	COG0523	cobalamin synthesis protein
B0E33_15850	COG0583	DNA-binding transcription factor activity
B0E33_15860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B0E33_15870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B0E33_15885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_15895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_15905	COG0745	RESPONSE REGULATOR receiver
B0E33_15910	COG4191	Histidine kinase
B0E33_15910	COG0784	Response regulator, receiver
B0E33_15925	COG4957	zinc ion binding
B0E33_15935	COG1609	Transcriptional regulator
B0E33_15950	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_15975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B0E33_15980	COG0330	HflC and HflK could
B0E33_15995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B0E33_16000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B0E33_16000	COG0517	IMP dehydrogenase activity
B0E33_16010	COG2951	lytic endotransglycosylase activity
B0E33_16025	COG0067	glutamate synthase
B0E33_16025	COG0070	glutamate synthase
B0E33_16025	COG0069	glutamate synthase activity
B0E33_16035	COG3220	belongs to the UPF0276 family
B0E33_16055	COG0071	Belongs to the small heat shock protein (HSP20) family
B0E33_16070	COG0483	inositol monophosphate 1-phosphatase activity
B0E33_16090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B0E33_16095	COG0457	Tetratricopeptide repeat
B0E33_16100	COG2267	carboxylic ester hydrolase activity
B0E33_16105	COG0469	pyruvate kinase activity
B0E33_16125	COG3750	Belongs to the UPF0335 family
B0E33_16135	COG2204	response regulator
B0E33_16170	COG0564	pseudouridine synthase activity
B0E33_16180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B0E33_16185	COG0534	Mate efflux family protein
B0E33_16190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B0E33_16195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B0E33_16210	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_16230	COG1132	(ABC) transporter
B0E33_16235	COG0254	rRNA binding
B0E33_16270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_16275	COG3813	Protein conserved in bacteria
B0E33_16295	COG0483	inositol monophosphate 1-phosphatase activity
B0E33_16300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B0E33_16310	COG0352	thiamine-phosphate diphosphorylase activity
B0E33_16325	COG0126	phosphoglycerate kinase activity
B0E33_16375	COG1692	metallophosphoesterase
B0E33_16380	COG0217	transcriptional regulatory protein
B0E33_16395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B0E33_16400	COG0632	four-way junction helicase activity
B0E33_16410	COG2255	four-way junction helicase activity
B0E33_16415	COG2972	Histidine kinase
B0E33_16415	COG0840	transmembrane signaling receptor activity
B0E33_16420	COG0824	Thioesterase
B0E33_16440	COG0823	Involved in the tonB-independent uptake of proteins
B0E33_16445	COG2885	chlorophyll binding
B0E33_16455	COG0037	tRNA processing
B0E33_16460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B0E33_16465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B0E33_16480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0E33_16495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B0E33_16505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_16510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_16515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B0E33_16520	COG0564	pseudouridine synthase activity
B0E33_16560	COG0643	Histidine kinase
B0E33_16560	COG2198	Histidine kinase
B0E33_16565	COG0835	chemotaxis
B0E33_16575	COG2201	protein-glutamate methylesterase activity
B0E33_16580	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B0E33_16585	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B0E33_16600	COG1157	protein secretion by the type III secretion system
B0E33_16620	COG0668	transmembrane transport
B0E33_16630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0E33_16635	COG0747	negative chemotaxis
B0E33_16640	COG0601	transmembrane transport
B0E33_16645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_16650	COG0444	Belongs to the ABC transporter superfamily
B0E33_16655	COG4608	Belongs to the ABC transporter superfamily
B0E33_16665	COG0798	PFAM Bile acid sodium symporter
B0E33_16675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_16695	COG2183	response to ionizing radiation
B0E33_16705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B0E33_16710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_16725	COG0583	DNA-binding transcription factor activity
B0E33_16740	COG5598	trimethylamine methyltransferase
B0E33_16750	COG3842	ATPase activity
B0E33_16765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B0E33_16775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B0E33_16810	COG4176	ABC-type proline glycine betaine transport system permease component
B0E33_16815	COG0517	IMP dehydrogenase activity
B0E33_16815	COG4175	Glycine betaine
B0E33_16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_16830	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
B0E33_16845	COG3300	MHYT domain
B0E33_16845	COG5001	Diguanylate cyclase
B0E33_16855	COG1609	Transcriptional regulator
B0E33_16860	COG1653	transport
B0E33_16865	COG1175	transmembrane transport
B0E33_16870	COG0395	ABC-type sugar transport system, permease component
B0E33_16875	COG3842	ATPase activity
B0E33_16900	COG1785	Belongs to the alkaline phosphatase family
B0E33_16910	COG1349	DNA-binding transcription factor activity
B0E33_16915	COG3842	ATPase activity
B0E33_16920	COG1653	transport
B0E33_16930	COG0395	ABC-type sugar transport system, permease component
B0E33_16935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_16940	COG0840	transmembrane signaling receptor activity
B0E33_16945	COG3718	enzyme involved in inositol metabolism
B0E33_16950	COG1082	Xylose isomerase domain protein TIM barrel
B0E33_16955	COG3962	Belongs to the TPP enzyme family
B0E33_16965	COG1129	ABC transporter
B0E33_16970	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_16985	COG0673	inositol 2-dehydrogenase activity
B0E33_16990	COG0673	inositol 2-dehydrogenase activity
B0E33_16995	COG2249	NAD(P)H dehydrogenase (quinone) activity
B0E33_17015	COG3386	PFAM SMP-30 Gluconolaconase
B0E33_17020	COG0800	Aldolase
B0E33_17025	COG3734	2-keto-3-deoxy-galactonokinase
B0E33_17030	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_17040	COG0395	ABC-type sugar transport system, permease component
B0E33_17055	COG1414	Transcriptional regulator
B0E33_17075	COG0410	ABC transporter
B0E33_17115	COG0028	Belongs to the TPP enzyme family
B0E33_17120	COG0069	glutamate synthase activity
B0E33_17135	COG0156	8-amino-7-oxononanoate synthase activity
B0E33_17140	COG1309	transcriptional regulator
B0E33_17160	COG2030	dehydratase
B0E33_17185	COG1609	Transcriptional regulator
B0E33_17200	COG0395	ABC-type sugar transport system, permease component
B0E33_17215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B0E33_17220	COG1305	Transglutaminase-like
B0E33_17240	COG3483	tryptophan 2,3-dioxygenase activity
B0E33_17255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_17270	COG3842	ATPase activity
B0E33_17275	COG1175	transmembrane transport
B0E33_17280	COG0395	ABC-type sugar transport system, permease component
B0E33_17305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B0E33_17310	COG3383	formate dehydrogenase (NAD+) activity
B0E33_17315	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
B0E33_17320	COG3259	Nickel-dependent hydrogenase
B0E33_17330	COG0375	protein maturation
B0E33_17340	COG0298	carbon dioxide binding
B0E33_17350	COG0309	Hydrogenase expression formation protein (HypE)
B0E33_17415	COG0174	glutamine synthetase
B0E33_17465	COG0489	protein tyrosine kinase activity
B0E33_17505	COG3383	formate dehydrogenase (NAD+) activity
B0E33_17505	COG0243	molybdopterin cofactor binding
B0E33_17510	COG0437	4 iron, 4 sulfur cluster binding
B0E33_17530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B0E33_17540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_17550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_17555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B0E33_17565	COG2986	histidine ammonia-lyase
B0E33_17570	COG1228	amidohydrolase
B0E33_17600	COG0583	DNA-binding transcription factor activity
B0E33_17610	COG0747	negative chemotaxis
B0E33_17635	COG0642	Histidine kinase
B0E33_17645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B0E33_17650	COG3842	ATPase activity
B0E33_17670	COG1609	Transcriptional regulator
B0E33_17675	COG1629	transport
B0E33_17680	COG3720	iron ion transport
B0E33_17690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_17695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B0E33_17700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0E33_17725	COG1175	transmembrane transport
B0E33_17740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0E33_17780	COG3246	L-lysine catabolic process to acetate
B0E33_17810	COG1091	dTDP-4-dehydrorhamnose reductase activity
B0E33_17815	COG1609	Transcriptional regulator
B0E33_17825	COG1175	transmembrane transport
B0E33_17830	COG0395	ABC-type sugar transport system, permease component
B0E33_17840	COG3842	ATPase activity
B0E33_17855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_17875	COG1024	Enoyl-CoA hydratase
B0E33_17885	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_17905	COG1960	acyl-CoA dehydrogenase activity
B0E33_17910	COG0583	DNA-binding transcription factor activity
B0E33_17915	COG4336	lyase activity
B0E33_17940	COG3932	Exopolysaccharide synthesis, ExoD
B0E33_17955	COG5487	UPF0391 membrane protein
B0E33_17960	COG4325	translation initiation factor activity
B0E33_17975	COG0784	Response regulator, receiver
B0E33_17980	COG3237	CsbD-like
B0E33_17985	COG3920	Histidine kinase
B0E33_17985	COG2202	Pas domain
B0E33_18025	COG0784	Response regulator, receiver
B0E33_18045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B0E33_18080	COG0785	Cytochrome C biogenesis protein
B0E33_18090	COG0640	Transcriptional regulator
B0E33_18105	COG2391	methyltransferase activity
B0E33_18145	COG1312	Catalyzes the dehydration of D-mannonate
B0E33_18150	COG0246	Mannitol dehydrogenase
B0E33_18155	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_18165	COG1917	Cupin 2, conserved barrel domain protein
B0E33_18175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_18180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_18185	COG1904	glucuronate isomerase
B0E33_18190	COG1802	Transcriptional regulator
B0E33_18195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_18210	COG3971	2-oxopent-4-enoate hydratase activity
B0E33_18215	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0E33_18230	COG3384	dioxygenase
B0E33_18265	COG1215	transferase activity, transferring glycosyl groups
B0E33_18275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0E33_18280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0E33_18305	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_18310	COG5441	Belongs to the UPF0261 family
B0E33_18345	COG3842	ATPase activity
B0E33_18355	COG1840	ABC-type Fe3 transport system, periplasmic component
B0E33_18360	COG2204	response regulator
B0E33_18370	COG1840	ABC-type Fe3 transport system, periplasmic component
B0E33_18380	COG5002	protein histidine kinase activity
B0E33_18390	COG2831	hemolysin activation secretion protein
B0E33_18405	COG1846	Transcriptional regulator
B0E33_18465	COG1215	transferase activity, transferring glycosyl groups
B0E33_18465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B0E33_18480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B0E33_18510	COG0300	oxidoreductase activity
B0E33_18525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B0E33_18535	COG0765	amino acid transport
B0E33_18545	COG2186	Transcriptional regulator
B0E33_18550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B0E33_18560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B0E33_18575	COG1301	dicarboxylic acid transport
B0E33_18585	COG0251	oxidation-reduction process
B0E33_18595	COG2272	Belongs to the type-B carboxylesterase lipase family
B0E33_18625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_18630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_18650	COG2814	Major facilitator Superfamily
B0E33_18655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_18670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_18675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_18680	COG0765	amino acid transport
B0E33_18685	COG0765	amino acid transport
B0E33_18690	COG1126	abc transporter atp-binding protein
B0E33_18700	COG0673	inositol 2-dehydrogenase activity
B0E33_18710	COG1653	transport
B0E33_18730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_18735	COG3119	arylsulfatase activity
B0E33_18740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0E33_18740	COG2169	Transcriptional regulator
B0E33_18755	COG3145	DNA-N1-methyladenine dioxygenase activity
B0E33_18780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0E33_18780	COG2169	Transcriptional regulator
B0E33_18795	COG0583	DNA-binding transcription factor activity
B0E33_18800	COG0662	Cupin 2, conserved barrel domain protein
B0E33_18810	COG0154	amidase activity
B0E33_18815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_18820	COG1126	abc transporter atp-binding protein
B0E33_18825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B0E33_18830	COG0583	DNA-binding transcription factor activity
B0E33_18840	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B0E33_18840	COG0028	Belongs to the TPP enzyme family
B0E33_18845	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_18875	COG4977	sequence-specific DNA binding
B0E33_18910	COG1525	nuclease
B0E33_18970	COG1475	DNA binding
B0E33_19020	COG4962	Type ii secretion system protein e
B0E33_19035	COG3451	type IV secretory pathway VirB4
B0E33_19060	COG2948	multi-organism process
B0E33_19075	COG1431	PFAM Stem cell self-renewal protein Piwi
B0E33_19110	COG0482	sulfurtransferase activity
B0E33_19120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B0E33_19130	COG1766	The M ring may be actively involved in energy transduction
B0E33_19135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0E33_19145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0E33_19150	COG2204	response regulator
B0E33_19155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0E33_19175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B0E33_19190	COG0494	nUDIX hydrolase
B0E33_19195	COG0435	Glutathione S-transferase
B0E33_19220	COG0714	Associated with various cellular activities
B0E33_19230	COG0494	nUDIX hydrolase
B0E33_19240	COG0617	tRNA 3'-terminal CCA addition
B0E33_19245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B0E33_19250	COG0408	coproporphyrinogen oxidase activity
B0E33_19255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B0E33_19260	COG1132	(ABC) transporter
B0E33_19270	COG0840	transmembrane signaling receptor activity
B0E33_19285	COG1132	(ABC) transporter
B0E33_19295	COG2857	Cytochrome c1
B0E33_19295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B0E33_19300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B0E33_19300	COG2857	Cytochrome c1
B0E33_19310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B0E33_19315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B0E33_19320	COG0778	Nitroreductase
B0E33_19325	COG0456	acetyltransferase
B0E33_19335	COG2345	Transcriptional regulator
B0E33_19350	COG2030	dehydratase
B0E33_19360	COG1086	Polysaccharide biosynthesis protein
B0E33_19370	COG3273	potassium ion transport
B0E33_19370	COG0471	metal ion transport
B0E33_19375	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0E33_19380	COG0477	Major facilitator Superfamily
B0E33_19385	COG0012	GTP binding
B0E33_19400	COG0193	aminoacyl-tRNA hydrolase activity
B0E33_19405	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B0E33_19415	COG2258	MOSC domain
B0E33_19430	COG0402	S-adenosylhomocysteine deaminase activity
B0E33_19440	COG4603	Belongs to the binding-protein-dependent transport system permease family
B0E33_19450	COG1744	ABC transporter substrate-binding protein PnrA-like
B0E33_19455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B0E33_19465	COG0006	proline dipeptidase activity
B0E33_19480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B0E33_19500	COG3685	Protein conserved in bacteria
B0E33_19510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0E33_19520	COG2205	protein histidine kinase activity
B0E33_19525	COG0745	RESPONSE REGULATOR receiver
B0E33_19530	COG1846	Transcriptional regulator
B0E33_19545	COG3321	synthase
B0E33_19545	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_19545	COG0604	alcohol dehydrogenase
B0E33_19550	COG2814	Major facilitator Superfamily
B0E33_19555	COG0314	molybdopterin synthase activity
B0E33_19565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B0E33_19575	COG0725	ABC transporter, periplasmic molybdate-binding protein
B0E33_19585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0E33_19590	COG4977	sequence-specific DNA binding
B0E33_19590	COG1917	Cupin 2, conserved barrel domain protein
B0E33_19595	COG1970	mechanosensitive ion channel activity
B0E33_19600	COG1435	thymidine kinase activity
B0E33_19610	COG0457	Tetratricopeptide repeat
B0E33_19615	COG0457	Tetratricopeptide repeat
B0E33_19620	COG0322	excinuclease ABC activity
B0E33_19645	COG0667	Aldo Keto reductase
B0E33_19655	COG2192	nodulation
B0E33_19675	COG3842	ATPase activity
B0E33_19680	COG1178	ABC-type Fe3 transport system permease component
B0E33_19685	COG1349	DNA-binding transcription factor activity
B0E33_19690	COG3852	Histidine kinase
B0E33_19710	COG2801	Transposase and inactivated derivatives
B0E33_19775	COG0625	glutathione transferase activity
B0E33_19790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B0E33_19800	COG1278	Cold shock
B0E33_19810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B0E33_19825	COG5001	Diguanylate cyclase
B0E33_19825	COG3300	MHYT domain
B0E33_19830	COG2211	Major facilitator Superfamily
B0E33_19840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B0E33_19885	COG2827	Endonuclease containing a URI domain
B0E33_19890	COG0556	nucleotide-excision repair
B0E33_19915	COG3119	arylsulfatase activity
B0E33_19920	COG0747	negative chemotaxis
B0E33_19935	COG1309	transcriptional regulator
B0E33_19940	COG0789	Transcriptional regulator
B0E33_19950	COG0840	transmembrane signaling receptor activity
B0E33_20025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B0E33_20030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B0E33_20035	COG0583	DNA-binding transcription factor activity
B0E33_20040	COG0492	ferredoxin-NADP+ reductase activity
B0E33_20050	COG1522	sequence-specific DNA binding
B0E33_20065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B0E33_20070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B0E33_20080	COG0789	Transcriptional regulator
B0E33_20085	COG0505	Belongs to the CarA family
B0E33_20100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B0E33_20120	COG2271	Major facilitator Superfamily
B0E33_20130	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B0E33_20135	COG0330	HflC and HflK could
B0E33_20155	COG1309	transcriptional regulator
B0E33_20160	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_20170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B0E33_20180	COG1024	Enoyl-CoA hydratase
B0E33_20185	COG1309	transcriptional regulator
B0E33_20190	COG1802	Transcriptional regulator
B0E33_20195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_20215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0E33_20225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_20235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_20240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B0E33_20245	COG1309	transcriptional regulator
B0E33_20290	COG0628	permease
B0E33_20340	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_20345	COG0583	DNA-binding transcription factor activity
B0E33_20350	COG0583	DNA-binding transcription factor activity
B0E33_20370	COG0473	3-isopropylmalate dehydrogenase activity
B0E33_20390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_20395	COG0583	DNA-binding transcription factor activity
B0E33_20400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B0E33_20410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0E33_20430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B0E33_20460	COG0330	HflC and HflK could
B0E33_20490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0E33_20525	COG1305	Transglutaminase-like
B0E33_20575	COG1278	Cold shock
B0E33_20630	COG0482	sulfurtransferase activity
B0E33_20675	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B0E33_20680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_20685	COG1917	Cupin 2, conserved barrel domain protein
B0E33_20690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_20700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_20760	COG1473	amidohydrolase
B0E33_20770	COG4215	(ABC) transporter
B0E33_20775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_20785	COG1309	transcriptional regulator
B0E33_20800	COG3850	Histidine kinase
B0E33_20800	COG4999	Histidine kinase
B0E33_20800	COG3437	response regulator, receiver
B0E33_20800	COG2205	protein histidine kinase activity
B0E33_20805	COG2197	response regulator
B0E33_20820	COG2304	oxidoreductase activity
B0E33_20835	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0E33_20835	COG0824	Thioesterase
B0E33_20840	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_20845	COG3246	L-lysine catabolic process to acetate
B0E33_20860	COG1960	acyl-CoA dehydrogenase activity
B0E33_20950	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_20965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0E33_21010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B0E33_21020	COG1280	lysine exporter protein (LysE YggA)
B0E33_21100	COG0431	NADPH-dependent FMN reductase
B0E33_21105	COG5001	Diguanylate cyclase
B0E33_21105	COG3300	MHYT domain
B0E33_21110	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B0E33_21115	COG3023	N-Acetylmuramoyl-L-alanine amidase
B0E33_21140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B0E33_21145	COG0840	transmembrane signaling receptor activity
B0E33_21175	COG2001	Belongs to the MraZ family
B0E33_21180	COG0275	rRNA processing
B0E33_21195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B0E33_21205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B0E33_21210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B0E33_21225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B0E33_21235	COG1181	Belongs to the D-alanine--D-alanine ligase family
B0E33_21240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B0E33_21245	COG0849	cell division
B0E33_21250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B0E33_21260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0E33_21265	COG0497	DNA recombination
B0E33_21285	COG0210	DNA helicase
B0E33_21305	COG0006	proline dipeptidase activity
B0E33_21315	COG0038	chloride channel
B0E33_21320	COG0038	chloride channel
B0E33_21330	COG0277	FAD linked oxidase domain protein
B0E33_21360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B0E33_21400	COG0330	HflC and HflK could
B0E33_21405	COG0330	HflC and HflK could
B0E33_21425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B0E33_21455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B0E33_21480	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_21485	COG2207	Transcriptional regulator
B0E33_21490	COG0384	phenazine biosynthesis protein PhzF
B0E33_21495	COG0494	nUDIX hydrolase
B0E33_21500	COG1741	Belongs to the pirin family
B0E33_21505	COG1131	(ABC) transporter
B0E33_21510	COG0456	acetyltransferase
B0E33_21515	COG0842	Transport permease protein
B0E33_21520	COG1686	Belongs to the peptidase S11 family
B0E33_21525	COG3706	GGDEF domain
B0E33_21530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B0E33_21550	COG0583	DNA-binding transcription factor activity
B0E33_21565	COG0693	protein deglycase activity
B0E33_21575	COG2943	transferase activity, transferring hexosyl groups
B0E33_21585	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B0E33_21590	COG0579	oxidoreductase
B0E33_21595	COG0154	amidase activity
B0E33_21605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B0E33_21625	COG2375	cellular response to nickel ion
B0E33_21640	COG1522	sequence-specific DNA binding
B0E33_21645	COG0523	cobalamin synthesis protein
B0E33_21660	COG1280	lysine exporter protein (LysE YggA)
B0E33_21670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B0E33_21685	COG3706	GGDEF domain
B0E33_21690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0E33_21705	COG0440	acetolactate synthase activity
B0E33_21710	COG0028	Belongs to the TPP enzyme family
B0E33_21750	COG0840	transmembrane signaling receptor activity
B0E33_21780	COG1522	sequence-specific DNA binding
B0E33_21785	COG0686	Belongs to the AlaDH PNT family
B0E33_21830	COG3237	CsbD-like
B0E33_21840	COG0129	dihydroxy-acid dehydratase activity
B0E33_21845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B0E33_21875	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B0E33_21885	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_21900	COG0697	spore germination
B0E33_21910	COG4067	protein conserved in archaea
B0E33_21910	COG0189	ligase activity
B0E33_21915	COG0189	ligase activity
B0E33_21920	COG2226	methyltransferase
B0E33_21930	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B0E33_21950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B0E33_21955	COG0351	phosphomethylpyrimidine kinase
B0E33_21960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_21965	COG2067	long-chain fatty acid transport protein
B0E33_21980	COG0438	transferase activity, transferring glycosyl groups
B0E33_22005	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_22015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B0E33_22020	COG1127	ABC transporter
B0E33_22030	COG3218	ABC-type transport auxiliary lipoprotein component
B0E33_22030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B0E33_22045	COG0300	oxidoreductase activity
B0E33_22060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_22090	COG0633	Ferredoxin
B0E33_22105	COG0589	response to stress
B0E33_22125	COG0673	inositol 2-dehydrogenase activity
B0E33_22140	COG3768	UPF0283 membrane protein
B0E33_22145	COG3106	COG3106 Predicted ATPase
B0E33_22160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B0E33_22165	COG1749	Flagellar hook protein flgE
B0E33_22205	COG5443	negative regulation of bacterial-type flagellum assembly
B0E33_22220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B0E33_22240	COG3951	Flagellar rod assembly protein muramidase FlgJ
B0E33_22245	COG1706	bacterial-type flagellum-dependent cell motility
B0E33_22255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B0E33_22260	COG0737	Belongs to the 5'-nucleotidase family
B0E33_22280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B0E33_22290	COG4786	Flagellar basal body rod
B0E33_22295	COG4786	Flagellar basal body rod
B0E33_22335	COG1338	Plays a role in the flagellum-specific transport system
B0E33_22350	COG1815	bacterial-type flagellum-dependent cell motility
B0E33_22355	COG1558	bacterial-type flagellum-dependent cell motility
B0E33_22360	COG1677	Flagellar hook-basal body complex protein FliE
B0E33_22365	COG1987	bacterial-type flagellum assembly
B0E33_22370	COG1684	flagellar biosynthetic protein fliR
B0E33_22375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0E33_22405	COG4589	Belongs to the CDS family
B0E33_22410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B0E33_22425	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
B0E33_22435	COG1960	acyl-CoA dehydrogenase activity
B0E33_22440	COG0583	DNA-binding transcription factor activity
B0E33_22450	COG3738	Protein conserved in bacteria
B0E33_22460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B0E33_22465	COG2197	response regulator
B0E33_22475	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_22485	COG1335	isochorismatase
B0E33_22500	COG1309	transcriptional regulator
B0E33_22540	COG0625	glutathione transferase activity
B0E33_22560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0E33_22565	COG0601	transmembrane transport
B0E33_22570	COG1652	LysM domain
B0E33_22575	COG0697	spore germination
B0E33_22600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_22605	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_22620	COG0435	Glutathione S-transferase
B0E33_22655	COG1132	(ABC) transporter
B0E33_22670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B0E33_22675	COG3383	formate dehydrogenase (NAD+) activity
B0E33_22690	COG0583	DNA-binding transcription factor activity
B0E33_22735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
B0E33_22735	COG3264	Mechanosensitive ion channel
B0E33_22740	COG2313	pseudouridylate synthase activity
B0E33_22745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0E33_22750	COG2226	methyltransferase
B0E33_22770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0E33_22785	COG0390	transport system, permease component
B0E33_22790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B0E33_22795	COG0538	isocitrate dehydrogenase activity
B0E33_22805	COG0477	Major facilitator Superfamily
B0E33_22815	COG5001	Diguanylate cyclase
B0E33_22820	COG1605	Chorismate mutase
B0E33_22845	COG2207	Transcriptional regulator
B0E33_22855	COG1846	Transcriptional regulator
B0E33_22880	COG3300	MHYT domain
B0E33_22880	COG5001	Diguanylate cyclase
B0E33_22900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B0E33_22905	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B0E33_22915	COG1652	LysM domain
B0E33_22915	COG2823	Periplasmic or secreted lipoprotein
B0E33_22935	COG0583	DNA-binding transcription factor activity
B0E33_22940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_22960	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_22975	COG4952	isomerase
B0E33_22980	COG3347	Dehydrogenase
B0E33_22980	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_22990	COG1879	ABC-type sugar transport system periplasmic component
B0E33_22995	COG1129	ABC transporter
B0E33_23000	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_23010	COG3254	rhamnose metabolic process
B0E33_23020	COG0037	tRNA processing
B0E33_23025	COG0583	DNA-binding transcription factor activity
B0E33_23040	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_23040	COG1388	LysM domain
B0E33_23070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B0E33_23080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B0E33_23105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_23120	COG4977	sequence-specific DNA binding
B0E33_23120	COG1917	Cupin 2, conserved barrel domain protein
B0E33_23130	COG0047	phosphoribosylformylglycinamidine synthase activity
B0E33_23140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B0E33_23150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B0E33_23190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B0E33_23200	COG0531	amino acid
B0E33_23225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0E33_23230	COG1522	sequence-specific DNA binding
B0E33_23250	COG0668	transmembrane transport
B0E33_23265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_23275	COG1126	abc transporter atp-binding protein
B0E33_23295	COG1410	methionine synthase
B0E33_23295	COG0646	methionine synthase
B0E33_23335	COG0745	RESPONSE REGULATOR receiver
B0E33_23365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B0E33_23370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_23375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_23380	COG1120	ATPase activity
B0E33_23395	COG0745	RESPONSE REGULATOR receiver
B0E33_23400	COG5002	protein histidine kinase activity
B0E33_23405	COG0583	DNA-binding transcription factor activity
B0E33_23410	COG0625	glutathione transferase activity
B0E33_23415	COG1017	nitric oxide dioxygenase activity
B0E33_23415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B0E33_23440	COG5310	Homospermidine synthase
B0E33_23465	COG0659	secondary active sulfate transmembrane transporter activity
B0E33_23490	COG0436	Aminotransferase
B0E33_23520	COG1309	transcriptional regulator
B0E33_23530	COG1703	isobutyryl-CoA mutase activity
B0E33_23555	COG0668	transmembrane transport
B0E33_23565	COG0433	COG0433 Predicted ATPase
B0E33_23605	COG3655	Transcriptional regulator
B0E33_23620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_23630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_23645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B0E33_23650	COG0477	Major facilitator Superfamily
B0E33_23655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B0E33_23665	COG2010	Cytochrome c
B0E33_23675	COG0251	oxidation-reduction process
B0E33_23690	COG0583	DNA-binding transcription factor activity
B0E33_23710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B0E33_23720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_23735	COG0702	epimerase
B0E33_23740	COG1733	regulation of RNA biosynthetic process
B0E33_23750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0E33_23770	COG1006	Multisubunit Na H antiporter MnhC subunit
B0E33_23785	COG2212	antiporter activity
B0E33_23790	COG1320	monovalent cation:proton antiporter activity
B0E33_23800	COG2166	iron-sulfur cluster assembly
B0E33_23840	COG0457	Tetratricopeptide repeat
B0E33_23855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0E33_23860	COG2983	Belongs to the UPF0260 family
B0E33_23875	COG0741	lytic transglycosylase activity
B0E33_23900	COG2353	YceI-like domain
B0E33_23905	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_23930	COG5425	PFAM Usg family protein
B0E33_23945	COG0142	geranyltranstransferase activity
B0E33_23950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B0E33_23960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B0E33_23960	COG0574	Belongs to the PEP-utilizing enzyme family
B0E33_23970	COG3300	MHYT domain
B0E33_23970	COG5001	Diguanylate cyclase
B0E33_23975	COG2003	Belongs to the UPF0758 family
B0E33_23980	COG0024	Methionine aminopeptidase
B0E33_23990	COG3454	Phosphonate metabolism
B0E33_23995	COG3639	organic phosphonate transmembrane transporter activity
B0E33_24010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B0E33_24020	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B0E33_24025	COG3639	organic phosphonate transmembrane transporter activity
B0E33_24030	COG2226	methyltransferase
B0E33_24035	COG1363	Peptidase, m42
B0E33_24045	COG0367	asparagine synthase
B0E33_24050	COG1846	Transcriptional regulator
B0E33_24055	COG3300	MHYT domain
B0E33_24055	COG5001	Diguanylate cyclase
B0E33_24060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B0E33_24065	COG1489	DNA binding
B0E33_24070	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_24075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B0E33_24080	COG1058	Belongs to the CinA family
B0E33_24080	COG1546	Belongs to the CinA family
B0E33_24085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0E33_24105	COG1024	Enoyl-CoA hydratase
B0E33_24155	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B0E33_24160	COG3005	denitrification pathway
B0E33_24165	COG3043	anaerobic respiration
B0E33_24170	COG0243	molybdopterin cofactor binding
B0E33_24185	COG4459	periplasmic nitrate reductase
B0E33_24190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B0E33_24195	COG0302	gtp cyclohydrolase
B0E33_24205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B0E33_24210	COG1032	radical SAM domain protein
B0E33_24220	COG1522	sequence-specific DNA binding
B0E33_24225	COG0456	acetyltransferase
B0E33_24230	COG0189	ligase activity
B0E33_24235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B0E33_24255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0E33_24290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B0E33_24295	COG3591	Belongs to the peptidase S1B family
B0E33_24305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0E33_24330	COG3707	response regulator
B0E33_24335	COG1116	anion transmembrane transporter activity
B0E33_24335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_24340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_24340	COG1116	anion transmembrane transporter activity
B0E33_24350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_24350	COG1116	anion transmembrane transporter activity
B0E33_24355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B0E33_24375	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B0E33_24380	COG0243	molybdopterin cofactor binding
B0E33_24385	COG1648	precorrin-2 dehydrogenase activity
B0E33_24385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0E33_24390	COG1802	Transcriptional regulator
B0E33_24425	COG4608	Belongs to the ABC transporter superfamily
B0E33_24430	COG0444	Belongs to the ABC transporter superfamily
B0E33_24435	COG0601	transmembrane transport
B0E33_24440	COG0747	negative chemotaxis
B0E33_24450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B0E33_24455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B0E33_24460	COG1845	cytochrome c oxidase, subunit III
B0E33_24465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B0E33_24475	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B0E33_24520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B0E33_24540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B0E33_24545	COG0081	regulation of translation
B0E33_24550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B0E33_24555	COG0222	ribosome binding
B0E33_24560	COG0085	RNA polymerase activity
B0E33_24575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B0E33_24580	COG0049	tRNA binding
B0E33_24585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B0E33_24590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B0E33_24595	COG0051	transcription antitermination factor activity, RNA binding
B0E33_24600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B0E33_24605	COG0088	Forms part of the polypeptide exit tunnel
B0E33_24610	COG0089	rRNA binding
B0E33_24615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B0E33_24625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B0E33_24630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B0E33_24635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B0E33_24645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B0E33_24650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B0E33_24655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B0E33_24660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B0E33_24665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B0E33_24670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B0E33_24685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B0E33_24690	COG1841	ribosomal large subunit assembly
B0E33_24695	COG0200	Binds to the 23S rRNA
B0E33_24700	COG0201	protein transport
B0E33_24705	COG0563	adenylate kinase activity
B0E33_24710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B0E33_24715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B0E33_24720	COG0202	RNA polymerase activity
B0E33_24725	COG0203	ribosomal protein L17
B0E33_24730	COG0840	transmembrane signaling receptor activity
B0E33_24740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B0E33_24750	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0E33_24770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B0E33_24775	COG0564	pseudouridine synthase activity
B0E33_24800	COG2239	Acts as a magnesium transporter
B0E33_24810	COG1305	Transglutaminase-like
B0E33_24820	COG2308	Evidence 4 Homologs of previously reported genes of
B0E33_24835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B0E33_24870	COG0697	spore germination
B0E33_24875	COG1254	Belongs to the acylphosphatase family
B0E33_24900	COG0321	lipoyl(octanoyl) transferase activity
B0E33_24905	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0E33_24930	COG2239	Acts as a magnesium transporter
B0E33_24945	COG1846	Transcriptional regulator
B0E33_24950	COG1764	response to oxidative stress
B0E33_24985	COG1960	acyl-CoA dehydrogenase activity
B0E33_25000	COG1309	transcriptional regulator
B0E33_25030	COG0740	serine-type endopeptidase activity
B0E33_25040	COG0745	RESPONSE REGULATOR receiver
B0E33_25040	COG3706	GGDEF domain
B0E33_25100	COG0484	heat shock protein binding
B0E33_25105	COG1686	Belongs to the peptidase S11 family
B0E33_25115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B0E33_25125	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_25150	COG0537	adenosine 5'-monophosphoramidase activity
B0E33_25175	COG0204	Acyl-transferase
B0E33_25175	COG0318	PFAM AMP-dependent synthetase and ligase
B0E33_25200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B0E33_25205	COG1309	transcriptional regulator
B0E33_25235	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B0E33_25265	COG3119	arylsulfatase activity
B0E33_25275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0E33_25280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B0E33_25310	COG0511	ligase activity, forming carbon-carbon bonds
B0E33_25330	COG1530	ribonuclease E activity
B0E33_25335	COG0860	N-Acetylmuramoyl-L-alanine amidase
B0E33_25340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0E33_25350	COG0739	heme binding
B0E33_25355	COG2833	Protein of unknown function (DUF455)
B0E33_25360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B0E33_25370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B0E33_25390	COG0174	glutamine synthetase
B0E33_25395	COG0347	Belongs to the P(II) protein family
B0E33_25405	COG2202	Pas domain
B0E33_25405	COG3920	Histidine kinase
B0E33_25415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B0E33_25415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B0E33_25425	COG0544	peptidyl-prolyl cis-trans isomerase activity
B0E33_25430	COG0740	serine-type endopeptidase activity
B0E33_25435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B0E33_25440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B0E33_25455	COG1231	oxidoreductase activity
B0E33_25480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0E33_25485	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0E33_25490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0E33_25500	COG0649	NAD binding
B0E33_25510	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B0E33_25520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B0E33_25530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0E33_25540	COG0713	ATP synthesis coupled electron transport
B0E33_25555	COG1007	ATP synthesis coupled electron transport
B0E33_25580	COG0442	prolyl-tRNA aminoacylation
B0E33_25590	COG1136	(ABC) transporter
B0E33_25595	COG0587	DNA-directed DNA polymerase activity
B0E33_25605	COG0747	negative chemotaxis
B0E33_25630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0E33_25635	COG0662	Cupin 2, conserved barrel domain protein
B0E33_25645	COG0052	Belongs to the universal ribosomal protein uS2 family
B0E33_25650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B0E33_25655	COG0528	UMP kinase activity
B0E33_25660	COG0233	cytoplasmic translational termination
B0E33_25675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B0E33_25680	COG0750	zinc metalloprotease
B0E33_25685	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0E33_25690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0E33_25695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B0E33_25700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0E33_25710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0E33_25715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B0E33_25730	COG0840	transmembrane signaling receptor activity
B0E33_25735	COG0372	Belongs to the citrate synthase family
B0E33_25740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B0E33_25745	COG2333	competence protein COMEC
B0E33_25745	COG0658	competence protein
B0E33_25750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B0E33_25770	COG0114	fumarate hydratase activity
B0E33_25780	COG1802	Transcriptional regulator
B0E33_25800	COG1558	bacterial-type flagellum-dependent cell motility
B0E33_25805	COG1677	Flagellar hook-basal body complex protein FliE
B0E33_25810	COG4786	Flagellar basal body rod
B0E33_25815	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B0E33_25820	COG1706	bacterial-type flagellum-dependent cell motility
B0E33_25840	COG1338	Plays a role in the flagellum-specific transport system
B0E33_25845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B0E33_25895	COG5442	Flagellar protein FlaF
B0E33_25900	COG5443	negative regulation of bacterial-type flagellum assembly
B0E33_25905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B0E33_25915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0E33_25920	COG1684	flagellar biosynthetic protein fliR
B0E33_25960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0E33_25965	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0E33_25970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0E33_25985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B0E33_25995	COG4786	Flagellar basal body rod
B0E33_26005	COG1157	protein secretion by the type III secretion system
B0E33_26015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_26015	COG4191	Histidine kinase
B0E33_26050	COG0315	cyclic pyranopterin monophosphate synthase activity
B0E33_26065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B0E33_26075	COG0149	triose-phosphate isomerase activity
B0E33_26085	COG0504	CTP synthase activity
B0E33_26120	COG0785	Cytochrome C biogenesis protein
B0E33_26135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B0E33_26140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B0E33_26150	COG2832	Protein of unknown function (DUF454)
B0E33_26160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B0E33_26165	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B0E33_26170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B0E33_26175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0E33_26185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B0E33_26190	COG0022	dehydrogenase e1 component
B0E33_26190	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0E33_26195	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0E33_26200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B0E33_26220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B0E33_26225	COG2867	negative regulation of translational initiation
B0E33_26245	COG1058	Belongs to the CinA family
B0E33_26245	COG1546	Belongs to the CinA family
B0E33_26250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B0E33_26250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B0E33_26260	COG3852	Histidine kinase
B0E33_26265	COG2204	response regulator
B0E33_26270	COG5000	phosphorelay sensor kinase activity
B0E33_26275	COG2204	response regulator
B0E33_26280	COG0569	domain protein
B0E33_26285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B0E33_26290	COG1923	regulation of RNA biosynthetic process
B0E33_26295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B0E33_26300	COG3956	TIGRFAM MazG family protein
B0E33_26305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_26310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_26340	COG1309	transcriptional regulator
B0E33_26370	COG2137	regulation of response to DNA damage stimulus
B0E33_26380	COG0084	hydrolase, TatD family'
B0E33_26385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B0E33_26395	COG1686	Belongs to the peptidase S11 family
B0E33_26410	COG3279	Response regulator of the LytR AlgR family
B0E33_26430	COG0542	response to heat
B0E33_26440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B0E33_26440	COG3608	succinylglutamate desuccinylase aspartoacylase
B0E33_26460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_26465	COG1116	anion transmembrane transporter activity
B0E33_26470	COG0010	Belongs to the arginase family
B0E33_26485	COG5001	Diguanylate cyclase
B0E33_26495	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0E33_26525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B0E33_26535	COG0583	DNA-binding transcription factor activity
B0E33_26545	COG1183	phosphatidylcholine synthase activity
B0E33_26555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0E33_26565	COG0679	Auxin Efflux Carrier
B0E33_26575	COG2301	Belongs to the HpcH HpaI aldolase family
B0E33_26610	COG0148	phosphopyruvate hydratase activity
B0E33_26620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B0E33_26635	COG0343	queuine tRNA-ribosyltransferase activity
B0E33_26640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B0E33_26645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B0E33_26650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B0E33_26665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B0E33_26670	COG2095	MarC family integral membrane protein
B0E33_26680	COG1733	regulation of RNA biosynthetic process
B0E33_26705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B0E33_26705	COG0519	Catalyzes the synthesis of GMP from XMP
B0E33_26715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B0E33_26715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B0E33_26725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B0E33_26730	COG0248	Ppx GppA phosphatase
B0E33_26770	COG1802	Transcriptional regulator
B0E33_26780	COG0006	proline dipeptidase activity
B0E33_26785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B0E33_26790	COG2423	ornithine cyclodeaminase activity
B0E33_26795	COG1522	sequence-specific DNA binding
B0E33_26800	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_26805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0E33_26815	COG1132	(ABC) transporter
B0E33_26830	COG1024	Enoyl-CoA hydratase
B0E33_26835	COG2050	protein possibly involved in aromatic compounds catabolism
B0E33_26845	COG2030	dehydratase
B0E33_26845	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_26850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B0E33_26855	COG2151	metal-sulfur cluster biosynthetic enzyme
B0E33_26860	COG3396	Phenylacetate-CoA oxygenase
B0E33_26865	COG3460	Phenylacetate-CoA oxygenase
B0E33_26875	COG3396	Phenylacetate-CoA oxygenase
B0E33_26890	COG2989	Protein conserved in bacteria
B0E33_26900	COG0629	single-stranded DNA binding
B0E33_26905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B0E33_26920	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B0E33_26940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B0E33_26960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0E33_26970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B0E33_26975	COG0805	protein transport
B0E33_26980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B0E33_26985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B0E33_26990	COG3842	ATPase activity
B0E33_26995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B0E33_27000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B0E33_27005	COG1472	Belongs to the glycosyl hydrolase 3 family
B0E33_27020	COG0583	DNA-binding transcription factor activity
B0E33_27030	COG0018	arginyl-trna synthetase
B0E33_27035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B0E33_27040	COG0316	Belongs to the HesB IscA family
B0E33_27055	COG0187	DNA topoisomerase II activity
B0E33_27065	COG0513	Belongs to the DEAD box helicase family
B0E33_27070	COG0745	RESPONSE REGULATOR receiver
B0E33_27070	COG3706	GGDEF domain
B0E33_27075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B0E33_27080	COG0316	Belongs to the HesB IscA family
B0E33_27085	COG2151	metal-sulfur cluster biosynthetic enzyme
B0E33_27090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B0E33_27095	COG0719	Fe-S assembly protein
B0E33_27100	COG0396	ATPase activity
B0E33_27105	COG0719	Fe-S assembly protein
B0E33_27110	COG1104	cysteine desulfurase activity
B0E33_27115	COG2945	thiolester hydrolase activity
B0E33_27135	COG0525	valine-tRNA ligase activity
B0E33_27155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0E33_27170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B0E33_27190	COG1492	cobalamin metabolic process
B0E33_27230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B0E33_27235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B0E33_27240	COG2188	Transcriptional regulator
B0E33_27245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B0E33_27255	COG3142	Participates in the control of copper homeostasis
B0E33_27270	COG0395	ABC-type sugar transport system, permease component
B0E33_27280	COG3842	ATPase activity
B0E33_27305	COG1737	Transcriptional regulator
B0E33_27310	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_27340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B0E33_27345	COG0300	oxidoreductase activity
B0E33_27360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B0E33_27365	COG1280	lysine exporter protein (LysE YggA)
B0E33_27385	COG3791	Glutathione-dependent formaldehyde-activating
B0E33_27390	COG2897	thiosulfate sulfurtransferase activity
B0E33_27405	COG1309	transcriptional regulator
B0E33_27415	COG1126	abc transporter atp-binding protein
B0E33_27420	COG0765	amino acid transport
B0E33_27425	COG4597	amino acid ABC transporter
B0E33_27430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0E33_27435	COG0626	cystathionine gamma-synthase activity
B0E33_27445	COG0463	Glycosyl transferase, family 2
B0E33_27450	COG0671	phosphoesterase, PA-phosphatase related
B0E33_27460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B0E33_27535	COG1278	Cold shock
B0E33_27540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B0E33_27580	COG0811	peptide transport
B0E33_27615	COG2885	chlorophyll binding
B0E33_27635	COG3501	Rhs element vgr protein
B0E33_27690	COG0739	heme binding
B0E33_27690	COG0741	lytic transglycosylase activity
B0E33_27690	COG1196	nuclear chromosome segregation
B0E33_27725	COG2423	ornithine cyclodeaminase activity
B0E33_27730	COG0387	Pfam Sodium calcium exchanger
B0E33_27735	COG0410	ABC transporter
B0E33_27740	COG1129	ABC transporter
B0E33_27750	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0E33_27785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B0E33_27790	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B0E33_27805	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0E33_27805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0E33_27815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B0E33_27825	COG0306	phosphate transporter
B0E33_27835	COG0306	phosphate transporter
B0E33_27855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B0E33_27860	COG1494	fructose-1,6-bisphosphatase
B0E33_27870	COG0436	Aminotransferase
B0E33_27875	COG2199	diguanylate cyclase activity
B0E33_27885	COG3243	poly(R)-hydroxyalkanoic acid synthase
B0E33_27905	COG0010	Belongs to the arginase family
B0E33_27920	COG0402	S-adenosylhomocysteine deaminase activity
B0E33_27930	COG0789	Transcriptional regulator
B0E33_27940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B0E33_27965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B0E33_27970	COG0646	methionine synthase
B0E33_27970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B0E33_27975	COG5598	trimethylamine methyltransferase
B0E33_27985	COG0156	8-amino-7-oxononanoate synthase activity
B0E33_27990	COG4221	oxidoreductase activity
B0E33_28015	COG2942	2-epimerase
B0E33_28020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B0E33_28045	COG5001	Diguanylate cyclase
B0E33_28065	COG2353	YceI-like domain
B0E33_28070	COG3038	cytochrome b561
B0E33_28080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B0E33_28080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B0E33_28085	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_28090	COG1309	transcriptional regulator
B0E33_28110	COG0415	Belongs to the DNA photolyase family
B0E33_28115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B0E33_28120	COG2814	Major facilitator Superfamily
B0E33_28125	COG0489	protein tyrosine kinase activity
B0E33_28145	COG3135	benzoate transporter
B0E33_28150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B0E33_28155	COG0746	molybdenum cofactor guanylyltransferase activity
B0E33_28160	COG1763	Mo-molybdopterin cofactor biosynthetic process
B0E33_28165	COG0303	'Molybdopterin
B0E33_28170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B0E33_28175	COG0583	DNA-binding transcription factor activity
B0E33_28180	COG0625	glutathione transferase activity
B0E33_28205	COG0626	cystathionine gamma-synthase activity
B0E33_28210	COG0583	DNA-binding transcription factor activity
B0E33_28215	COG2084	Dehydrogenase
B0E33_28235	COG4638	Rieske (2fe-2S)
B0E33_28240	COG1902	pentaerythritol trinitrate reductase activity
B0E33_28240	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0E33_28260	COG1522	sequence-specific DNA binding
B0E33_28265	COG1573	uracil-dna glycosylase
B0E33_28270	COG2202	Pas domain
B0E33_28270	COG2205	protein histidine kinase activity
B0E33_28275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B0E33_28280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B0E33_28300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B0E33_28360	COG0697	spore germination
B0E33_28365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_28370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_28390	COG1294	oxidase, subunit
B0E33_28395	COG1271	oxidase subunit
B0E33_28400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B0E33_28405	COG4988	ABC transporter
B0E33_28430	COG0583	DNA-binding transcription factor activity
B0E33_28440	COG2267	carboxylic ester hydrolase activity
B0E33_28450	COG1609	Transcriptional regulator
B0E33_28455	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_28470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0E33_28475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0E33_28480	COG1609	Transcriptional regulator
B0E33_28485	COG3842	ATPase activity
B0E33_28490	COG0395	ABC-type sugar transport system, permease component
B0E33_28495	COG1175	transmembrane transport
B0E33_28510	COG0154	amidase activity
B0E33_28530	COG2197	response regulator
B0E33_28580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_28585	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_28590	COG0371	Dehydrogenase
B0E33_28600	COG1175	transmembrane transport
B0E33_28615	COG1070	Carbohydrate kinase
B0E33_28620	COG0277	FAD linked oxidase domain protein
B0E33_28625	COG1609	Transcriptional regulator
B0E33_28645	COG2204	response regulator
B0E33_28650	COG1181	Belongs to the D-alanine--D-alanine ligase family
B0E33_28670	COG0438	transferase activity, transferring glycosyl groups
B0E33_28705	COG0438	transferase activity, transferring glycosyl groups
B0E33_28710	COG0463	Glycosyl transferase, family 2
B0E33_28715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_28760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B0E33_28765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B0E33_28795	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B0E33_28815	COG1850	ribulose-bisphosphate carboxylase activity
B0E33_28820	COG0287	Prephenate dehydrogenase
B0E33_28825	COG1879	ABC-type sugar transport system periplasmic component
B0E33_28835	COG1129	ABC transporter
B0E33_28840	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_28855	COG2186	Transcriptional regulator
B0E33_28900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0E33_28905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_28915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0E33_28925	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0E33_28930	COG3831	ATPase activity
B0E33_28940	COG4974	Belongs to the 'phage' integrase family
B0E33_28950	COG1629	transport
B0E33_28950	COG4774	siderophore transport
B0E33_28955	COG2867	negative regulation of translational initiation
B0E33_28955	COG2226	methyltransferase
B0E33_28960	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_28965	COG3433	isochorismatase activity
B0E33_28965	COG1535	isochorismatase
B0E33_28970	COG1021	2,3-dihydroxybenzoate-AMP ligase
B0E33_28980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B0E33_28985	COG2226	methyltransferase
B0E33_28985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B0E33_28985	COG3433	isochorismatase activity
B0E33_28995	COG1609	Transcriptional regulator
B0E33_29000	COG0673	inositol 2-dehydrogenase activity
B0E33_29010	COG1653	transport
B0E33_29015	COG1175	transmembrane transport
B0E33_29020	COG3833	ABC-type maltose transport systems, permease component
B0E33_29025	COG3842	ATPase activity
B0E33_29030	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B0E33_29035	COG2076	Multidrug Resistance protein
B0E33_29045	COG0590	tRNA wobble adenosine to inosine editing
B0E33_29060	COG2972	Histidine kinase
B0E33_29060	COG0745	RESPONSE REGULATOR receiver
B0E33_29065	COG3279	Response regulator of the LytR AlgR family
B0E33_29095	COG0384	phenazine biosynthesis protein PhzF
B0E33_29100	COG0583	DNA-binding transcription factor activity
B0E33_29115	COG4585	Histidine kinase
B0E33_29120	COG1879	ABC-type sugar transport system periplasmic component
B0E33_29125	COG1129	ABC transporter
B0E33_29135	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29140	COG3386	PFAM SMP-30 Gluconolaconase
B0E33_29145	COG1609	Transcriptional regulator
B0E33_29155	COG1129	ABC transporter
B0E33_29160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0E33_29180	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29185	COG1063	alcohol dehydrogenase
B0E33_29190	COG1129	ABC transporter
B0E33_29200	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29215	COG0246	Mannitol dehydrogenase
B0E33_29220	COG1940	carbohydrate kinase activity
B0E33_29235	COG1879	ABC-type sugar transport system periplasmic component
B0E33_29240	COG1129	ABC transporter
B0E33_29245	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B0E33_29275	COG0183	Belongs to the thiolase family
B0E33_29305	COG0156	8-amino-7-oxononanoate synthase activity
B0E33_29325	COG1845	cytochrome c oxidase, subunit III
B0E33_29335	COG0714	Associated with various cellular activities
B0E33_29350	COG2010	Cytochrome c
B0E33_29355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0E33_29360	COG2010	Cytochrome c
B0E33_29365	COG3391	amine dehydrogenase activity
B0E33_29475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B0E33_29480	COG0163	prenyltransferase activity
B0E33_29495	COG2376	Dihydroxyacetone kinase
B0E33_29500	COG1461	Dihydroxyacetone kinase
B0E33_29520	COG1129	ABC transporter
B0E33_29525	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29535	COG2390	Transcriptional regulator
B0E33_29540	COG1349	DNA-binding transcription factor activity
B0E33_29545	COG1879	ABC-type sugar transport system periplasmic component
B0E33_29550	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0E33_29555	COG1129	ABC transporter
B0E33_29590	COG1349	DNA-binding transcription factor activity
B0E33_29615	COG0583	DNA-binding transcription factor activity
B0E33_29625	COG1280	lysine exporter protein (LysE YggA)
B0E33_29635	COG0395	ABC-type sugar transport system, permease component
B0E33_29640	COG1175	transmembrane transport
B0E33_29655	COG3534	alpha-L-arabinofuranosidase
B0E33_29665	COG0583	DNA-binding transcription factor activity
B0E33_29670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0E33_29680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0E33_29685	COG1053	succinate dehydrogenase
B0E33_29690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B0E33_29695	COG1024	Enoyl-CoA hydratase
B0E33_29700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B0E33_29705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0E33_29710	COG1012	belongs to the aldehyde dehydrogenase family
B0E33_29725	COG0625	glutathione transferase activity
B0E33_29730	COG5507	3-demethylubiquinone-9 3-methyltransferase
B0E33_29735	COG1733	regulation of RNA biosynthetic process
B0E33_29740	COG1737	Transcriptional regulator
B0E33_29750	COG1175	transmembrane transport
B0E33_29755	COG0395	ABC-type sugar transport system, permease component
B0E33_29765	COG3842	ATPase activity
B0E33_29790	COG4941	Belongs to the sigma-70 factor family
B0E33_29795	COG3795	YCII-related domain
B0E33_29810	COG2197	response regulator
B0E33_29815	COG3239	Fatty acid desaturase
B0E33_29820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B0E33_29830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_29835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0E33_29855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B0E33_29865	COG3707	response regulator
B0E33_29885	COG1137	ATPase activity
B0E33_29895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0E33_29910	COG1192	Involved in chromosome partitioning
B0E33_29915	COG1475	DNA binding
B0E33_29920	COG1414	Transcriptional regulator
B0E33_29925	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B0E33_29950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B0E33_29955	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
B0E33_30000	COG2010	Cytochrome c
B0E33_30005	COG2010	Cytochrome c
B0E33_30025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0E33_30030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0E33_30060	COG4948	Mandelate Racemase Muconate Lactonizing
B0E33_30065	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_30080	COG3254	rhamnose metabolic process
B0E33_30090	COG3842	ATPase activity
B0E33_30095	COG0395	ABC-type sugar transport system, permease component
B0E33_30100	COG1175	transmembrane transport
B0E33_30115	COG3618	amidohydrolase
B0E33_30135	COG1846	Transcriptional regulator
B0E33_30170	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B0E33_30185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0E33_30210	COG0745	RESPONSE REGULATOR receiver
B0E33_30215	COG0642	Histidine kinase
B0E33_30230	COG0583	DNA-binding transcription factor activity
B0E33_30235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B0E33_30250	COG1846	Transcriptional regulator
B0E33_30255	COG1028	Short-chain dehydrogenase reductase Sdr
B0E33_30260	COG4962	Type ii secretion system protein e
B0E33_30265	COG3838	Conjugal transfer protein Trbc
B0E33_30270	COG5268	conjugation
B0E33_30275	COG3451	type IV secretory pathway VirB4
B0E33_30280	COG5314	conjugation
B0E33_30290	COG3846	protein secretion by the type IV secretion system
B0E33_30295	COG3701	Conjugal transfer protein
B0E33_30355	COG2132	Multicopper oxidase
B0E33_30380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0E33_30385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0E33_30400	COG1999	signal sequence binding
B0E33_30405	COG2847	Copper chaperone PCu(A)C
B0E33_30415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B0E33_30415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B0E33_30420	COG0785	Cytochrome C biogenesis protein
B0E33_30435	COG1742	UPF0060 membrane protein
B0E33_30470	COG1476	TRANSCRIPTIONal
B0E33_30475	COG1525	nuclease
B0E33_30495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B0E33_30530	COG2184	nucleotidyltransferase activity
B0E33_30550	COG1414	Transcriptional regulator
B0E33_30555	COG1475	DNA binding
B0E33_30560	COG1192	Involved in chromosome partitioning
B0E33_30590	COG4957	zinc ion binding
B0E33_30625	COG3838	Conjugal transfer protein Trbc
B0E33_30630	COG5268	conjugation
B0E33_30650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B0E33_30655	COG0739	heme binding
B0E33_30665	COG1321	iron dependent repressor
B0E33_30680	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B0E33_30685	COG3639	organic phosphonate transmembrane transporter activity
B0E33_30700	COG3034	peptidoglycan biosynthetic process
B0E33_30715	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_30720	COG1376	ErfK ybiS ycfS ynhG family protein
B0E33_30720	COG1388	LysM domain
B0E33_30725	COG1230	cation diffusion facilitator family transporter
B0E33_30735	COG0789	Transcriptional regulator
B0E33_30745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B0E33_30755	COG1999	signal sequence binding
B0E33_30765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B0E33_30785	COG5278	phosphoserine phosphatase activity
B0E33_30785	COG0840	transmembrane signaling receptor activity