locus-tag	class	description
FIV03_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV03_00020	COG2135	peptidase activity
FIV03_00030	COG0494	nUDIX hydrolase
FIV03_00070	COG3119	arylsulfatase activity
FIV03_00120	COG2226	methyltransferase
FIV03_00125	COG2909	trisaccharide binding
FIV03_00140	COG0251	oxidation-reduction process
FIV03_00160	COG3246	L-lysine catabolic process to acetate
FIV03_00165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_00170	COG3842	ATPase activity
FIV03_00185	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_00190	COG0583	DNA-binding transcription factor activity
FIV03_00210	COG4106	trans-aconitate 2-methyltransferase activity
FIV03_00225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIV03_00235	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIV03_00255	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_00300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIV03_00305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIV03_00315	COG0751	glycine-tRNA ligase activity
FIV03_00320	COG3300	MHYT domain
FIV03_00320	COG5001	Diguanylate cyclase
FIV03_00325	COG0786	glutamate:sodium symporter activity
FIV03_00335	COG1704	LemA family
FIV03_00345	COG0752	glycyl-tRNA synthetase alpha subunit
FIV03_00370	COG1573	uracil-dna glycosylase
FIV03_00385	COG0513	Belongs to the DEAD box helicase family
FIV03_00390	COG2133	pyrroloquinoline quinone binding
FIV03_00395	COG0287	Prephenate dehydrogenase
FIV03_00395	COG1605	Chorismate mutase
FIV03_00400	COG0281	malic enzyme
FIV03_00400	COG0280	phosphate acetyltransferase
FIV03_00410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV03_00415	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIV03_00435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIV03_00440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIV03_00445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIV03_00450	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV03_00455	COG0356	it plays a direct role in the translocation of protons across the membrane
FIV03_00465	COG1196	nuclear chromosome segregation
FIV03_00480	COG1194	a g-specific adenine glycosylase
FIV03_00495	COG0673	inositol 2-dehydrogenase activity
FIV03_00500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIV03_00510	COG0765	amino acid transport
FIV03_00520	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIV03_00525	COG5001	Diguanylate cyclase
FIV03_00525	COG3300	MHYT domain
FIV03_00535	COG3284	Transcriptional regulator
FIV03_00535	COG3284	Transcriptional regulator
FIV03_00540	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_00550	COG1733	regulation of RNA biosynthetic process
FIV03_00565	COG1942	4-Oxalocrotonate Tautomerase
FIV03_00575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIV03_00605	COG2226	methyltransferase
FIV03_00610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV03_00615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV03_00625	COG0509	glycine decarboxylation via glycine cleavage system
FIV03_00630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIV03_00640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIV03_00645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIV03_00650	COG0328	RNA-DNA hybrid ribonuclease activity
FIV03_00655	COG1597	lipid kinase activity
FIV03_00665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV03_00670	COG0612	Peptidase, M16
FIV03_00680	COG1678	Uncharacterized ACR, COG1678
FIV03_00690	COG0678	peroxiredoxin activity
FIV03_00690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIV03_00695	COG3346	SURF1 family
FIV03_00720	COG0109	protoheme IX farnesyltransferase activity
FIV03_00725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIV03_00730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIV03_00750	COG1011	Hydrolase
FIV03_00755	COG0312	modulator of DNA gyrase
FIV03_00765	COG1663	tetraacyldisaccharide 4'-kinase activity
FIV03_00770	COG1519	Transferase
FIV03_00785	COG0483	inositol monophosphate 1-phosphatase activity
FIV03_00790	COG0312	modulator of DNA gyrase
FIV03_00805	COG0151	Belongs to the GarS family
FIV03_00810	COG0596	Alpha beta hydrolase
FIV03_00815	COG5001	Diguanylate cyclase
FIV03_00820	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV03_00835	COG0742	ribosomal rna small subunit methyltransferase
FIV03_00840	COG1187	pseudouridine synthase activity
FIV03_00845	COG0590	tRNA wobble adenosine to inosine editing
FIV03_00870	COG1309	transcriptional regulator
FIV03_00890	COG0745	RESPONSE REGULATOR receiver
FIV03_00895	COG2030	dehydratase
FIV03_00900	COG0196	riboflavin kinase activity
FIV03_00920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIV03_00930	COG0612	Peptidase, M16
FIV03_00935	COG0612	Peptidase, M16
FIV03_00955	COG2204	response regulator
FIV03_00965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIV03_00970	COG0459	protein refolding
FIV03_00975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIV03_00990	COG0625	glutathione transferase activity
FIV03_00995	COG2900	Belongs to the SlyX family
FIV03_01005	COG1136	(ABC) transporter
FIV03_01005	COG0577	efflux transmembrane transporter activity
FIV03_01010	COG1136	(ABC) transporter
FIV03_01025	COG1607	acyl-coa hydrolase
FIV03_01040	COG1959	2 iron, 2 sulfur cluster binding
FIV03_01065	COG0124	histidyl-tRNA synthetase
FIV03_01070	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIV03_01075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIV03_01080	COG2818	Glycosylase
FIV03_01095	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_01100	COG0038	chloride channel
FIV03_01105	COG0247	lactate metabolic process
FIV03_01120	COG0277	FAD linked oxidase domain protein
FIV03_01125	COG0277	FAD linked oxidase domain protein
FIV03_01130	COG0583	DNA-binding transcription factor activity
FIV03_01145	COG0477	Major facilitator Superfamily
FIV03_01160	COG2186	Transcriptional regulator
FIV03_01165	COG1304	FMN binding
FIV03_01190	COG0583	DNA-binding transcription factor activity
FIV03_01195	COG0583	DNA-binding transcription factor activity
FIV03_01220	COG1570	exodeoxyribonuclease VII activity
FIV03_01255	COG4191	Histidine kinase
FIV03_01265	COG1042	CoA-binding domain protein
FIV03_01265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV03_01265	COG0045	succinate-CoA ligase (ADP-forming) activity
FIV03_01275	COG0583	DNA-binding transcription factor activity
FIV03_01280	COG1733	regulation of RNA biosynthetic process
FIV03_01305	COG1196	nuclear chromosome segregation
FIV03_01305	COG3264	Mechanosensitive ion channel
FIV03_01315	COG2351	hydroxyisourate hydrolase activity
FIV03_01325	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FIV03_01340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIV03_01365	COG1414	Transcriptional regulator
FIV03_01370	COG3257	ureidoglycine aminohydrolase activity
FIV03_01380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_01395	COG0028	Belongs to the TPP enzyme family
FIV03_01420	COG0730	response to heat
FIV03_01430	COG1741	Belongs to the pirin family
FIV03_01435	COG2388	GCN5-related N-acetyl-transferase
FIV03_01455	COG2169	Transcriptional regulator
FIV03_01455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV03_01555	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV03_01600	COG1177	transmembrane transport
FIV03_01605	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_01610	COG3842	ATPase activity
FIV03_01620	COG0174	glutamine synthetase
FIV03_01630	COG0174	glutamine synthetase
FIV03_01645	COG3795	YCII-related domain
FIV03_01650	COG4941	Belongs to the sigma-70 factor family
FIV03_01675	COG3706	GGDEF domain
FIV03_01680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV03_01690	COG0175	sulfate reduction
FIV03_01695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV03_01705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV03_01705	COG1648	precorrin-2 dehydrogenase activity
FIV03_01725	COG0183	Belongs to the thiolase family
FIV03_01730	COG0366	Alpha amylase catalytic
FIV03_01735	COG0463	Glycosyl transferase, family 2
FIV03_01745	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_01755	COG1309	transcriptional regulator
FIV03_01770	COG4175	Glycine betaine
FIV03_01770	COG0517	IMP dehydrogenase activity
FIV03_01775	COG1278	Cold shock
FIV03_01785	COG1671	Belongs to the UPF0178 family
FIV03_01805	COG1959	2 iron, 2 sulfur cluster binding
FIV03_01810	COG1609	Transcriptional regulator
FIV03_01815	COG2081	HI0933 family
FIV03_01820	COG0683	leucine binding
FIV03_01830	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_01835	COG0410	ABC transporter
FIV03_01845	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIV03_01850	COG3300	MHYT domain
FIV03_01850	COG5001	Diguanylate cyclase
FIV03_01860	COG1760	l-serine dehydratase
FIV03_01870	COG1802	Transcriptional regulator
FIV03_01875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIV03_01880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_01900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV03_01915	COG1278	Cold shock
FIV03_01940	COG3852	Histidine kinase
FIV03_01950	COG0398	Pfam SNARE associated Golgi protein
FIV03_01955	COG0594	ribonuclease P activity
FIV03_01960	COG0706	membrane insertase activity
FIV03_01985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIV03_01995	COG3739	integral membrane protein
FIV03_02010	COG0183	Belongs to the thiolase family
FIV03_02015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIV03_02025	COG1414	Transcriptional regulator
FIV03_02030	COG1090	epimerase
FIV03_02050	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_02055	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_02060	COG2017	converts alpha-aldose to the beta-anomer
FIV03_02065	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_02070	COG1129	ABC transporter
FIV03_02080	COG2186	Transcriptional regulator
FIV03_02085	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_02090	COG2203	Gaf domain
FIV03_02090	COG3706	GGDEF domain
FIV03_02090	COG4251	negative regulation of phosphorylation
FIV03_02090	COG5001	Diguanylate cyclase
FIV03_02100	COG2171	N-acyltransferase activity
FIV03_02110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV03_02120	COG0668	transmembrane transport
FIV03_02130	COG0101	tRNA pseudouridine synthase activity
FIV03_02145	COG2095	MarC family integral membrane protein
FIV03_02150	COG0242	peptide deformylase activity
FIV03_02175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIV03_02215	COG4964	Belongs to the GSP D family
FIV03_02255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIV03_02280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV03_02290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_02295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIV03_02310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV03_02315	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIV03_02320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIV03_02325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIV03_02330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIV03_02335	COG0295	cytidine deaminase activity
FIV03_02375	COG1803	Methylglyoxal synthase
FIV03_02380	COG0837	glucose binding
FIV03_02385	COG1643	Atp-dependent helicase
FIV03_02400	COG1522	sequence-specific DNA binding
FIV03_02405	COG4134	Bacterial extracellular solute-binding protein
FIV03_02410	COG4135	transport system, permease component
FIV03_02415	COG4136	ATPase activity
FIV03_02430	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_02440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIV03_02445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV03_02455	COG0450	alkyl hydroperoxide reductase
FIV03_02465	COG1278	Cold shock
FIV03_02475	COG1032	radical SAM domain protein
FIV03_02485	COG0400	carboxylic ester hydrolase activity
FIV03_02495	COG1363	Peptidase, m42
FIV03_02510	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIV03_02520	COG0481	GTPase activity
FIV03_02525	COG2824	Alkylphosphonate utilization operon protein PhnA
FIV03_02530	COG0583	DNA-binding transcription factor activity
FIV03_02535	COG1942	4-Oxalocrotonate Tautomerase
FIV03_02545	COG0583	DNA-binding transcription factor activity
FIV03_02550	COG1295	ribonuclease BN
FIV03_02555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIV03_02565	COG0072	phenylalanine-tRNA ligase activity
FIV03_02565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV03_02620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV03_02635	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_02645	COG0183	Belongs to the thiolase family
FIV03_02665	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_02690	COG0789	Transcriptional regulator
FIV03_02695	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV03_02695	COG1902	pentaerythritol trinitrate reductase activity
FIV03_02715	COG1309	transcriptional regulator
FIV03_02725	COG1802	Transcriptional regulator
FIV03_02730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIV03_02735	COG3180	Ammonia monooxygenase
FIV03_02755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV03_02780	COG0811	peptide transport
FIV03_02785	COG0848	biopolymer transport protein
FIV03_02800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV03_02800	COG2169	Transcriptional regulator
FIV03_02810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV03_02815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIV03_02890	COG2391	methyltransferase activity
FIV03_02905	COG3706	GGDEF domain
FIV03_02935	COG1595	DNA-templated transcription, initiation
FIV03_02950	COG4335	DNA alkylation repair
FIV03_02960	COG0395	ABC-type sugar transport system, permease component
FIV03_02970	COG1653	transport
FIV03_02985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV03_02995	COG0587	DNA-directed DNA polymerase activity
FIV03_03005	COG0346	lactoylglutathione lyase activity
FIV03_03015	COG0587	DNA-directed DNA polymerase activity
FIV03_03025	COG0667	Aldo Keto reductase
FIV03_03075	COG0583	DNA-binding transcription factor activity
FIV03_03080	COG2814	Major facilitator Superfamily
FIV03_03085	COG0667	Aldo Keto reductase
FIV03_03100	COG2807	transmembrane transport
FIV03_03120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIV03_03135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV03_03140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIV03_03150	COG0754	glutathionylspermidine amidase activity
FIV03_03155	COG1842	Phage shock protein A
FIV03_03160	COG3789	protein conserved in bacteria
FIV03_03175	COG3766	membrane
FIV03_03185	COG0386	Belongs to the glutathione peroxidase family
FIV03_03190	COG3443	Belongs to the bacterial solute-binding protein 9 family
FIV03_03200	COG0583	DNA-binding transcription factor activity
FIV03_03205	COG0697	spore germination
FIV03_03210	COG0823	Involved in the tonB-independent uptake of proteins
FIV03_03220	COG0584	glycerophosphoryl diester phosphodiesterase
FIV03_03225	COG3842	ATPase activity
FIV03_03230	COG3833	ABC-type maltose transport systems, permease component
FIV03_03290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIV03_03300	COG0539	negative regulation of cytoplasmic translation
FIV03_03335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_03350	COG1047	Peptidyl-prolyl cis-trans
FIV03_03355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_03375	COG0616	signal peptide processing
FIV03_03380	COG0776	regulation of translation
FIV03_03405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIV03_03415	COG1074	ATP-dependent DNA helicase activity
FIV03_03420	COG2887	Belongs to the helicase family. UvrD subfamily
FIV03_03425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIV03_03430	COG0802	atpase or kinase
FIV03_03435	COG2205	protein histidine kinase activity
FIV03_03445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV03_03450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV03_03455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV03_03455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV03_03465	COG2205	protein histidine kinase activity
FIV03_03470	COG0745	RESPONSE REGULATOR receiver
FIV03_03475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIV03_03485	COG1280	lysine exporter protein (LysE YggA)
FIV03_03490	COG3608	succinylglutamate desuccinylase aspartoacylase
FIV03_03490	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIV03_03495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV03_03505	COG3300	MHYT domain
FIV03_03505	COG5001	Diguanylate cyclase
FIV03_03510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIV03_03515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIV03_03520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIV03_03525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIV03_03530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV03_03540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIV03_03545	COG4974	Belongs to the 'phage' integrase family
FIV03_03575	COG0789	Transcriptional regulator
FIV03_03595	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_03605	COG1280	lysine exporter protein (LysE YggA)
FIV03_03615	COG0567	Dehydrogenase, E1 component
FIV03_03620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIV03_03630	COG0045	succinate-CoA ligase (ADP-forming) activity
FIV03_03635	COG0039	L-malate dehydrogenase activity
FIV03_03640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIV03_03645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIV03_03675	COG0514	ATP-dependent DNA helicase (RecQ)
FIV03_03685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV03_03700	COG4452	Inner membrane protein CreD
FIV03_03710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV03_03740	COG2066	Belongs to the glutaminase family
FIV03_03755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIV03_03760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIV03_03765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIV03_03800	COG2816	NAD+ diphosphatase activity
FIV03_03815	COG0659	secondary active sulfate transmembrane transporter activity
FIV03_03830	COG4172	Belongs to the ABC transporter superfamily
FIV03_03835	COG4239	(ABC) transporter, permease
FIV03_03840	COG4174	ABC transporter (Permease)
FIV03_03845	COG4166	transmembrane transport
FIV03_03850	COG4166	transmembrane transport
FIV03_03860	COG3474	cytochrome
FIV03_03865	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIV03_03870	COG1605	Chorismate mutase
FIV03_03870	COG0077	Prephenate dehydratase
FIV03_03875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_03885	COG0076	glutamate decarboxylase activity
FIV03_03895	COG4221	oxidoreductase activity
FIV03_03910	COG2133	pyrroloquinoline quinone binding
FIV03_03935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV03_03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_03965	COG4566	intracellular signal transduction
FIV03_03975	COG4191	Histidine kinase
FIV03_04020	COG2197	response regulator
FIV03_04025	COG1704	LemA family
FIV03_04050	COG2304	oxidoreductase activity
FIV03_04060	COG0588	phosphoglycerate mutase activity
FIV03_04065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIV03_04070	COG3300	MHYT domain
FIV03_04070	COG5001	Diguanylate cyclase
FIV03_04080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIV03_04085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIV03_04090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIV03_04095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIV03_04110	COG0779	Required for maturation of 30S ribosomal subunits
FIV03_04115	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIV03_04120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIV03_04125	COG1396	sequence-specific DNA binding
FIV03_04130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIV03_04135	COG1253	flavin adenine dinucleotide binding
FIV03_04140	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIV03_04145	COG1702	phosphate starvation-inducible protein PhoH
FIV03_04150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIV03_04185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIV03_04195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIV03_04205	COG3963	phosphatidate phosphatase activity
FIV03_04210	COG0484	heat shock protein binding
FIV03_04215	COG0443	Heat shock 70 kDa protein
FIV03_04225	COG3145	DNA-N1-methyladenine dioxygenase activity
FIV03_04240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIV03_04245	COG2226	methyltransferase
FIV03_04250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV03_04255	COG1024	Enoyl-CoA hydratase
FIV03_04260	COG0268	Binds directly to 16S ribosomal RNA
FIV03_04270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV03_04275	COG0592	DNA-directed DNA polymerase activity
FIV03_04285	COG0187	DNA topoisomerase II activity
FIV03_04295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIV03_04300	COG3046	protein related to deoxyribodipyrimidine photolyase
FIV03_04380	COG4974	Belongs to the 'phage' integrase family
FIV03_04390	COG0019	diaminopimelate decarboxylase activity
FIV03_04400	COG4172	Belongs to the ABC transporter superfamily
FIV03_04425	COG5598	trimethylamine methyltransferase
FIV03_04430	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_04435	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_04440	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_04445	COG0583	DNA-binding transcription factor activity
FIV03_04455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_04460	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_04480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV03_04485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_04530	COG0840	transmembrane signaling receptor activity
FIV03_04545	COG2208	phosphoserine phosphatase activity
FIV03_04555	COG1366	Belongs to the anti-sigma-factor antagonist family
FIV03_04560	COG0631	protein serine/threonine phosphatase activity
FIV03_04570	COG2815	serine threonine protein kinase
FIV03_04570	COG0515	serine threonine protein kinase
FIV03_04590	COG1177	transmembrane transport
FIV03_04595	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_04605	COG3842	ATPase activity
FIV03_04610	COG0683	leucine binding
FIV03_04645	COG1720	tRNA m6t6A37 methyltransferase activity
FIV03_04650	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_04650	COG1024	Enoyl-CoA hydratase
FIV03_04660	COG1960	acyl-CoA dehydrogenase activity
FIV03_04680	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_04690	COG0438	transferase activity, transferring glycosyl groups
FIV03_04750	COG0583	DNA-binding transcription factor activity
FIV03_04755	COG1960	acyl-CoA dehydrogenase activity
FIV03_04770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIV03_04785	COG0671	phosphoesterase, PA-phosphatase related
FIV03_04840	COG2814	Major facilitator Superfamily
FIV03_04850	COG2115	Belongs to the xylose isomerase family
FIV03_04855	COG1070	Carbohydrate kinase
FIV03_04865	COG4214	carbohydrate transport
FIV03_04870	COG4213	ABC transporter substrate-binding protein
FIV03_04875	COG1846	Transcriptional regulator
FIV03_04875	COG1940	carbohydrate kinase activity
FIV03_04895	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV03_04905	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_04915	COG1116	anion transmembrane transporter activity
FIV03_04920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_04950	COG5001	Diguanylate cyclase
FIV03_04950	COG3300	MHYT domain
FIV03_04960	COG0778	Nitroreductase
FIV03_04965	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FIV03_04985	COG1269	ATP hydrolysis coupled proton transport
FIV03_05010	COG5001	Diguanylate cyclase
FIV03_05010	COG3300	MHYT domain
FIV03_05020	COG1609	Transcriptional regulator
FIV03_05035	COG0395	ABC-type sugar transport system, permease component
FIV03_05040	COG3842	ATPase activity
FIV03_05055	COG0667	Aldo Keto reductase
FIV03_05060	COG3507	Belongs to the glycosyl hydrolase 43 family
FIV03_05075	COG1653	transport
FIV03_05085	COG0395	ABC-type sugar transport system, permease component
FIV03_05095	COG0837	glucose binding
FIV03_05100	COG0583	DNA-binding transcription factor activity
FIV03_05110	COG0596	Alpha beta hydrolase
FIV03_05115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV03_05120	COG3485	protocatechuate 3,4-dioxygenase
FIV03_05125	COG3485	protocatechuate 3,4-dioxygenase
FIV03_05130	COG3246	L-lysine catabolic process to acetate
FIV03_05135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIV03_05140	COG0583	DNA-binding transcription factor activity
FIV03_05150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV03_05165	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_05170	COG0625	glutathione transferase activity
FIV03_05195	COG0747	negative chemotaxis
FIV03_05200	COG0601	transmembrane transport
FIV03_05205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_05230	COG4608	Belongs to the ABC transporter superfamily
FIV03_05235	COG0747	negative chemotaxis
FIV03_05240	COG0601	transmembrane transport
FIV03_05250	COG0405	Gamma-glutamyltransferase
FIV03_05260	COG1177	transmembrane transport
FIV03_05265	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_05270	COG3842	ATPase activity
FIV03_05275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIV03_05325	COG0183	Belongs to the thiolase family
FIV03_05330	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_05335	COG1268	BioY protein
FIV03_05340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FIV03_05345	COG1122	ATPase activity
FIV03_05365	COG0583	DNA-binding transcription factor activity
FIV03_05380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_05390	COG1393	Belongs to the ArsC family
FIV03_05405	COG0747	negative chemotaxis
FIV03_05415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_05420	COG4172	Belongs to the ABC transporter superfamily
FIV03_05425	COG2217	Heavy metal translocating P-type atpase
FIV03_05430	COG0129	dihydroxy-acid dehydratase activity
FIV03_05440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_05450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_05455	COG1595	DNA-templated transcription, initiation
FIV03_05470	COG4191	Histidine kinase
FIV03_05480	COG4149	molybdate abc transporter
FIV03_05505	COG0456	acetyltransferase
FIV03_05510	COG1162	GTPase activity
FIV03_05515	COG0372	Belongs to the citrate synthase family
FIV03_05520	COG0372	Belongs to the citrate synthase family
FIV03_05525	COG0583	DNA-binding transcription factor activity
FIV03_05540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_05555	COG1522	sequence-specific DNA binding
FIV03_05570	COG0189	ligase activity
FIV03_05575	COG0792	nuclease activity
FIV03_05580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIV03_05595	COG3384	dioxygenase
FIV03_05610	COG0756	dUTP diphosphatase activity
FIV03_05615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV03_05620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV03_05625	COG0010	Belongs to the arginase family
FIV03_05635	COG0393	Putative heavy-metal-binding
FIV03_05640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV03_05650	COG3284	Transcriptional regulator
FIV03_05660	COG1858	cytochrome C peroxidase
FIV03_05665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIV03_05675	COG0606	chelatase, subunit chli
FIV03_05715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV03_05715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV03_05735	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIV03_05750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIV03_05760	COG0180	Tryptophanyl-tRNA synthetase
FIV03_05780	COG0784	Response regulator, receiver
FIV03_05780	COG2205	protein histidine kinase activity
FIV03_05780	COG5002	protein histidine kinase activity
FIV03_05790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIV03_05800	COG0583	DNA-binding transcription factor activity
FIV03_05830	COG0052	Belongs to the universal ribosomal protein uS2 family
FIV03_05835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIV03_05840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIV03_05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIV03_05860	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIV03_05870	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FIV03_05880	COG0840	transmembrane signaling receptor activity
FIV03_05885	COG1309	transcriptional regulator
FIV03_05890	COG0251	oxidation-reduction process
FIV03_05895	COG0596	Alpha beta hydrolase
FIV03_05900	COG1072	(Pantothenic acid kinase))
FIV03_05905	COG0140	phosphoribosyl-ATP diphosphatase activity
FIV03_05910	COG0107	imidazoleglycerol-phosphate synthase activity
FIV03_05915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIV03_05925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIV03_05935	COG0131	Imidazoleglycerol-phosphate dehydratase
FIV03_05945	COG0284	orotidine-5'-phosphate decarboxylase activity
FIV03_05970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV03_05980	COG0285	dihydrofolate synthase activity
FIV03_05985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIV03_05990	COG0159	tryptophan synthase activity
FIV03_06005	COG0133	tryptophan synthase activity
FIV03_06010	COG0135	phosphoribosylanthranilate isomerase activity
FIV03_06020	COG0280	phosphate acetyltransferase
FIV03_06020	COG0281	malic enzyme
FIV03_06025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIV03_06040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIV03_06055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIV03_06065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV03_06085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIV03_06090	COG0237	dephospho-CoA kinase activity
FIV03_06095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV03_06105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIV03_06110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIV03_06120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIV03_06135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIV03_06140	COG0445	tRNA wobble uridine modification
FIV03_06145	COG0357	Ribosomal RNA small subunit methyltransferase G
FIV03_06150	COG1192	Involved in chromosome partitioning
FIV03_06155	COG1475	DNA binding
FIV03_06170	COG0495	leucyl-tRNA aminoacylation
FIV03_06180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIV03_06190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV03_06225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIV03_06230	COG1605	Chorismate mutase
FIV03_06230	COG0287	Prephenate dehydrogenase
FIV03_06235	COG0228	four-way junction DNA binding
FIV03_06240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIV03_06250	COG0336	Belongs to the RNA methyltransferase TrmD family
FIV03_06255	COG0335	large ribosomal subunit rRNA binding
FIV03_06260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIV03_06280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV03_06290	COG2304	oxidoreductase activity
FIV03_06300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIV03_06305	COG0830	nickel cation binding
FIV03_06320	COG0804	urea catabolic process
FIV03_06330	COG3755	Protein conserved in bacteria
FIV03_06335	COG0832	Belongs to the urease beta subunit family
FIV03_06340	COG0831	urea catabolic process
FIV03_06360	COG0523	cobalamin synthesis protein
FIV03_06365	COG1946	Acyl-CoA thioesterase
FIV03_06370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV03_06375	COG0300	oxidoreductase activity
FIV03_06395	COG4520	surface antigen
FIV03_06405	COG1595	DNA-templated transcription, initiation
FIV03_06415	COG2086	electron transfer activity
FIV03_06420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIV03_06425	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_06450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV03_06455	COG0165	Argininosuccinate lyase
FIV03_06465	COG0019	diaminopimelate decarboxylase activity
FIV03_06475	COG0745	RESPONSE REGULATOR receiver
FIV03_06480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FIV03_06480	COG0037	tRNA processing
FIV03_06490	COG2884	Cell division ATP-binding protein ftsE
FIV03_06510	COG1953	Uracil, thiamine, allantoin
FIV03_06520	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FIV03_06540	COG2301	Belongs to the HpcH HpaI aldolase family
FIV03_06550	COG3119	arylsulfatase activity
FIV03_06570	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV03_06575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV03_06580	COG2918	glutathione biosynthetic process
FIV03_06580	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV03_06595	COG0436	Aminotransferase
FIV03_06610	COG0501	Belongs to the peptidase M48B family
FIV03_06635	COG2270	Major facilitator Superfamily
FIV03_06640	COG2902	Dehydrogenase
FIV03_06650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIV03_06655	COG0066	3-isopropylmalate dehydratase activity
FIV03_06665	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FIV03_06680	COG0745	RESPONSE REGULATOR receiver
FIV03_06695	COG2321	neutral zinc metallopeptidase
FIV03_06700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIV03_06705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIV03_06710	COG0552	protein localization to endoplasmic reticulum
FIV03_06750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV03_06760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV03_06765	COG0287	Prephenate dehydrogenase
FIV03_06770	COG0142	geranyltranstransferase activity
FIV03_06775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV03_06780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIV03_06785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIV03_06795	COG2917	probably involved in intracellular septation
FIV03_06830	COG0405	Gamma-glutamyltransferase
FIV03_06860	COG1115	amino acid carrier protein
FIV03_06865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIV03_06875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV03_06890	COG0604	alcohol dehydrogenase
FIV03_06905	COG2186	Transcriptional regulator
FIV03_06965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIV03_06990	COG0556	nucleotide-excision repair
FIV03_07040	COG0629	single-stranded DNA binding
FIV03_07080	COG1192	Involved in chromosome partitioning
FIV03_07130	COG4962	Type ii secretion system protein e
FIV03_07145	COG3451	type IV secretory pathway VirB4
FIV03_07160	COG3846	protein secretion by the type IV secretion system
FIV03_07175	COG2948	multi-organism process
FIV03_07185	COG0583	DNA-binding transcription factor activity
FIV03_07190	COG0183	Belongs to the thiolase family
FIV03_07195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIV03_07205	COG1414	Transcriptional regulator
FIV03_07220	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_07245	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_07250	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_07255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_07265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_07270	COG1063	alcohol dehydrogenase
FIV03_07275	COG0583	DNA-binding transcription factor activity
FIV03_07285	COG3485	protocatechuate 3,4-dioxygenase
FIV03_07290	COG3485	protocatechuate 3,4-dioxygenase
FIV03_07300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV03_07305	COG0583	DNA-binding transcription factor activity
FIV03_07380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_07425	COG1846	Transcriptional regulator
FIV03_07445	COG1414	Transcriptional regulator
FIV03_07475	COG4783	chaperone-mediated protein folding
FIV03_07480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV03_07485	COG1329	Transcriptional regulator
FIV03_07505	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIV03_07515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIV03_07525	COG3487	Iron-regulated protein
FIV03_07575	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIV03_07580	COG3454	Phosphonate metabolism
FIV03_07585	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIV03_07590	COG4778	phosphonate C-P lyase system protein PhnL
FIV03_07595	COG4107	phosphonate C-P lyase system protein PhnK
FIV03_07600	COG3627	carbon phosphorus lyase activity
FIV03_07605	COG0346	lactoylglutathione lyase activity
FIV03_07610	COG3626	phosphonate metabolism
FIV03_07615	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FIV03_07620	COG3624	Phosphonate C-P lyase system protein PhnG
FIV03_07625	COG2188	Transcriptional regulator
FIV03_07695	COG4555	ABC transporter
FIV03_07715	COG1280	lysine exporter protein (LysE YggA)
FIV03_07745	COG1802	Transcriptional regulator
FIV03_07760	COG0583	DNA-binding transcription factor activity
FIV03_07765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV03_07785	COG3025	triphosphatase activity
FIV03_07855	COG1238	metal cluster binding
FIV03_07875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIV03_07905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_07925	COG0670	Belongs to the BI1 family
FIV03_07940	COG4181	ATPase activity
FIV03_07950	COG0667	Aldo Keto reductase
FIV03_07955	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FIV03_07965	COG0438	transferase activity, transferring glycosyl groups
FIV03_07980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV03_07995	COG0024	Methionine aminopeptidase
FIV03_08010	COG0671	phosphoesterase, PA-phosphatase related
FIV03_08020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV03_08025	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIV03_08045	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIV03_08050	COG0347	Belongs to the P(II) protein family
FIV03_08055	COG0004	ammonium transporteR
FIV03_08060	COG0004	ammonium transporteR
FIV03_08065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV03_08070	COG0395	ABC-type sugar transport system, permease component
FIV03_08075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIV03_08090	COG1597	lipid kinase activity
FIV03_08100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV03_08110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV03_08125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_08130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV03_08140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV03_08145	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV03_08150	COG4133	protoheme IX ABC transporter activity
FIV03_08180	COG0714	Associated with various cellular activities
FIV03_08200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIV03_08215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIV03_08220	COG0602	queuosine metabolic process
FIV03_08225	COG0720	synthase
FIV03_08230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIV03_08260	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_08305	COG2835	tetraacyldisaccharide 4'-kinase activity
FIV03_08310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIV03_08330	COG4413	Urea transporter
FIV03_08355	COG0405	Gamma-glutamyltransferase
FIV03_08370	COG3012	SEC-C Motif Domain Protein
FIV03_08385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV03_08390	COG0840	transmembrane signaling receptor activity
FIV03_08395	COG4974	Belongs to the 'phage' integrase family
FIV03_08405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIV03_08410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIV03_08415	COG4536	flavin adenine dinucleotide binding
FIV03_08445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIV03_08460	COG0825	malonyl-CoA metabolic process
FIV03_08465	COG3034	peptidoglycan biosynthetic process
FIV03_08475	COG0494	nUDIX hydrolase
FIV03_08490	COG2197	response regulator
FIV03_08495	COG2030	dehydratase
FIV03_08505	COG2391	methyltransferase activity
FIV03_08525	COG2814	Major facilitator Superfamily
FIV03_08535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIV03_08540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIV03_08575	COG0840	transmembrane signaling receptor activity
FIV03_08580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIV03_08590	COG1595	DNA-templated transcription, initiation
FIV03_08605	COG0708	Exodeoxyribonuclease III
FIV03_08625	COG4991	sh3 domain protein
FIV03_08635	COG2226	methyltransferase
FIV03_08660	COG0288	reversible hydration of carbon dioxide
FIV03_08670	COG0235	Class ii aldolase
FIV03_08680	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FIV03_08690	COG1129	ABC transporter
FIV03_08695	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_08710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV03_08715	COG0840	transmembrane signaling receptor activity
FIV03_08715	COG3290	protein histidine kinase activity
FIV03_08725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_08730	COG1120	ATPase activity
FIV03_08765	COG0583	DNA-binding transcription factor activity
FIV03_08770	COG0697	spore germination
FIV03_08780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIV03_08805	COG0640	Transcriptional regulator
FIV03_08815	COG2814	Major facilitator Superfamily
FIV03_08835	COG1846	Transcriptional regulator
FIV03_08845	COG0346	lactoylglutathione lyase activity
FIV03_08855	COG0473	3-isopropylmalate dehydrogenase activity
FIV03_08870	COG1473	amidohydrolase
FIV03_08875	COG2264	protein methyltransferase activity
FIV03_08890	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIV03_08905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIV03_08910	COG0181	hydroxymethylbilane synthase activity
FIV03_08940	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIV03_09070	COG4383	Mu-like prophage protein gp29
FIV03_09075	COG4373	Mu-like prophage FluMu protein gp28
FIV03_09230	COG0745	RESPONSE REGULATOR receiver
FIV03_09240	COG1024	Enoyl-CoA hydratase
FIV03_09250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV03_09265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIV03_09275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV03_09285	COG2326	polyphosphate kinase activity
FIV03_09310	COG0483	inositol monophosphate 1-phosphatase activity
FIV03_09315	COG3842	ATPase activity
FIV03_09325	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV03_09330	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV03_09335	COG0745	RESPONSE REGULATOR receiver
FIV03_09350	COG0673	inositol 2-dehydrogenase activity
FIV03_09360	COG1024	Enoyl-CoA hydratase
FIV03_09370	COG1609	Transcriptional regulator
FIV03_09390	COG3842	ATPase activity
FIV03_09420	COG1609	Transcriptional regulator
FIV03_09430	COG0546	phosphoglycolate phosphatase activity
FIV03_09435	COG1595	DNA-templated transcription, initiation
FIV03_09440	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIV03_09445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIV03_09455	COG3339	Conserved Protein
FIV03_09500	COG1285	pathogenesis
FIV03_09510	COG1295	ribonuclease BN
FIV03_09535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV03_09535	COG0596	Alpha beta hydrolase
FIV03_09555	COG0463	Glycosyl transferase, family 2
FIV03_09560	COG0653	protein targeting
FIV03_09565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV03_09570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIV03_09575	COG0494	nUDIX hydrolase
FIV03_09590	COG1040	competence protein
FIV03_09600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV03_09625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV03_09630	COG0527	aspartate kinase activity
FIV03_09640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIV03_09645	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV03_09680	COG0739	heme binding
FIV03_09715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_09725	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_09735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_09745	COG0583	DNA-binding transcription factor activity
FIV03_09750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_09760	COG1177	transmembrane transport
FIV03_09765	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_09770	COG3842	ATPase activity
FIV03_09775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIV03_09785	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_09800	COG2197	response regulator
FIV03_09825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_09845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIV03_09850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIV03_09860	COG4214	carbohydrate transport
FIV03_09875	COG1609	Transcriptional regulator
FIV03_09905	COG2378	regulation of single-species biofilm formation
FIV03_09910	COG3002	Belongs to the UPF0753 family
FIV03_09920	COG0583	DNA-binding transcription factor activity
FIV03_09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV03_09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_09950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIV03_09960	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_09970	COG1420	regulation of RNA biosynthetic process
FIV03_09985	COG0765	amino acid transport
FIV03_09990	COG1126	abc transporter atp-binding protein
FIV03_09995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV03_10000	COG3938	Belongs to the proline racemase family
FIV03_10005	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_10010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_10015	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_10020	COG3938	Belongs to the proline racemase family
FIV03_10035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIV03_10040	COG0246	Mannitol dehydrogenase
FIV03_10055	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV03_10070	COG2186	Transcriptional regulator
FIV03_10085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIV03_10135	COG3246	L-lysine catabolic process to acetate
FIV03_10145	COG3485	protocatechuate 3,4-dioxygenase
FIV03_10150	COG0625	glutathione transferase activity
FIV03_10190	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_10195	COG3971	2-oxopent-4-enoate hydratase activity
FIV03_10205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIV03_10230	COG1414	Transcriptional regulator
FIV03_10255	COG2204	response regulator
FIV03_10260	COG3852	Histidine kinase
FIV03_10275	COG1129	ABC transporter
FIV03_10280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_10285	COG2390	Transcriptional regulator
FIV03_10290	COG0667	Aldo Keto reductase
FIV03_10295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIV03_10305	COG1070	Carbohydrate kinase
FIV03_10315	COG1396	sequence-specific DNA binding
FIV03_10315	COG3800	Transcriptional regulator
FIV03_10325	COG0583	DNA-binding transcription factor activity
FIV03_10340	COG0738	Major facilitator superfamily
FIV03_10365	COG0583	DNA-binding transcription factor activity
FIV03_10380	COG1902	pentaerythritol trinitrate reductase activity
FIV03_10400	COG1864	DNA RNA non-specific endonuclease
FIV03_10400	COG3591	Belongs to the peptidase S1B family
FIV03_10420	COG2885	chlorophyll binding
FIV03_10425	COG1609	Transcriptional regulator
FIV03_10430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV03_10445	COG0436	Aminotransferase
FIV03_10450	COG0523	cobalamin synthesis protein
FIV03_10465	COG0583	DNA-binding transcription factor activity
FIV03_10475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIV03_10485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV03_10500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_10510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_10520	COG0745	RESPONSE REGULATOR receiver
FIV03_10525	COG0784	Response regulator, receiver
FIV03_10525	COG4191	Histidine kinase
FIV03_10540	COG4957	zinc ion binding
FIV03_10550	COG1609	Transcriptional regulator
FIV03_10565	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_10590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIV03_10595	COG0330	HflC and HflK could
FIV03_10605	COG1360	Flagellar Motor Protein
FIV03_10610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIV03_10615	COG0517	IMP dehydrogenase activity
FIV03_10615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIV03_10625	COG2951	lytic endotransglycosylase activity
FIV03_10640	COG0070	glutamate synthase
FIV03_10640	COG0067	glutamate synthase
FIV03_10640	COG0069	glutamate synthase activity
FIV03_10650	COG3220	belongs to the UPF0276 family
FIV03_10670	COG0071	Belongs to the small heat shock protein (HSP20) family
FIV03_10685	COG0483	inositol monophosphate 1-phosphatase activity
FIV03_10710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIV03_10715	COG0457	Tetratricopeptide repeat
FIV03_10720	COG2267	carboxylic ester hydrolase activity
FIV03_10725	COG0469	pyruvate kinase activity
FIV03_10745	COG3750	Belongs to the UPF0335 family
FIV03_10755	COG2204	response regulator
FIV03_10790	COG0564	pseudouridine synthase activity
FIV03_10805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIV03_10810	COG0534	Mate efflux family protein
FIV03_10815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIV03_10820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIV03_10835	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_10855	COG1132	(ABC) transporter
FIV03_10860	COG0254	rRNA binding
FIV03_10890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_10895	COG3813	Protein conserved in bacteria
FIV03_10915	COG0483	inositol monophosphate 1-phosphatase activity
FIV03_10920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIV03_10945	COG0126	phosphoglycerate kinase activity
FIV03_10995	COG1692	metallophosphoesterase
FIV03_11000	COG0217	transcriptional regulatory protein
FIV03_11015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIV03_11020	COG0632	four-way junction helicase activity
FIV03_11030	COG2255	four-way junction helicase activity
FIV03_11035	COG2972	Histidine kinase
FIV03_11035	COG0840	transmembrane signaling receptor activity
FIV03_11040	COG0824	Thioesterase
FIV03_11060	COG0823	Involved in the tonB-independent uptake of proteins
FIV03_11065	COG2885	chlorophyll binding
FIV03_11075	COG0037	tRNA processing
FIV03_11080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV03_11085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV03_11100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIV03_11105	COG0697	spore germination
FIV03_11115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIV03_11125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_11130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_11135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV03_11140	COG0564	pseudouridine synthase activity
FIV03_11180	COG2198	Histidine kinase
FIV03_11180	COG0643	Histidine kinase
FIV03_11185	COG0835	chemotaxis
FIV03_11195	COG2201	protein-glutamate methylesterase activity
FIV03_11200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIV03_11205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIV03_11225	COG1157	protein secretion by the type III secretion system
FIV03_11245	COG0668	transmembrane transport
FIV03_11255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIV03_11260	COG0747	negative chemotaxis
FIV03_11265	COG0601	transmembrane transport
FIV03_11270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_11275	COG0444	Belongs to the ABC transporter superfamily
FIV03_11280	COG4608	Belongs to the ABC transporter superfamily
FIV03_11290	COG0798	PFAM Bile acid sodium symporter
FIV03_11300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_11320	COG2183	response to ionizing radiation
FIV03_11330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV03_11335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_11355	COG0583	DNA-binding transcription factor activity
FIV03_11370	COG5598	trimethylamine methyltransferase
FIV03_11380	COG3842	ATPase activity
FIV03_11395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV03_11405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV03_11435	COG4176	ABC-type proline glycine betaine transport system permease component
FIV03_11440	COG0517	IMP dehydrogenase activity
FIV03_11440	COG4175	Glycine betaine
FIV03_11455	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FIV03_11470	COG5001	Diguanylate cyclase
FIV03_11470	COG3300	MHYT domain
FIV03_11480	COG1609	Transcriptional regulator
FIV03_11485	COG1653	transport
FIV03_11490	COG1175	transmembrane transport
FIV03_11495	COG0395	ABC-type sugar transport system, permease component
FIV03_11500	COG3842	ATPase activity
FIV03_11525	COG1785	Belongs to the alkaline phosphatase family
FIV03_11530	COG1349	DNA-binding transcription factor activity
FIV03_11535	COG3842	ATPase activity
FIV03_11540	COG1653	transport
FIV03_11555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_11560	COG0840	transmembrane signaling receptor activity
FIV03_11565	COG3718	enzyme involved in inositol metabolism
FIV03_11570	COG1082	Xylose isomerase domain protein TIM barrel
FIV03_11575	COG3962	Belongs to the TPP enzyme family
FIV03_11585	COG1129	ABC transporter
FIV03_11590	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_11605	COG0673	inositol 2-dehydrogenase activity
FIV03_11610	COG0673	inositol 2-dehydrogenase activity
FIV03_11615	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV03_11635	COG3386	PFAM SMP-30 Gluconolaconase
FIV03_11640	COG0800	Aldolase
FIV03_11645	COG3734	2-keto-3-deoxy-galactonokinase
FIV03_11650	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_11660	COG0395	ABC-type sugar transport system, permease component
FIV03_11675	COG1414	Transcriptional regulator
FIV03_11695	COG0410	ABC transporter
FIV03_11740	COG0028	Belongs to the TPP enzyme family
FIV03_11745	COG0069	glutamate synthase activity
FIV03_11760	COG0156	8-amino-7-oxononanoate synthase activity
FIV03_11765	COG1309	transcriptional regulator
FIV03_11785	COG2030	dehydratase
FIV03_11810	COG1609	Transcriptional regulator
FIV03_11825	COG0395	ABC-type sugar transport system, permease component
FIV03_11840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV03_11845	COG1305	Transglutaminase-like
FIV03_11865	COG3483	tryptophan 2,3-dioxygenase activity
FIV03_11875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_11890	COG3842	ATPase activity
FIV03_11895	COG1175	transmembrane transport
FIV03_11900	COG0395	ABC-type sugar transport system, permease component
FIV03_11925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIV03_11930	COG3383	formate dehydrogenase (NAD+) activity
FIV03_11935	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
FIV03_11940	COG3259	Nickel-dependent hydrogenase
FIV03_11955	COG0375	protein maturation
FIV03_11965	COG0298	carbon dioxide binding
FIV03_11975	COG0309	Hydrogenase expression formation protein (HypE)
FIV03_12040	COG0174	glutamine synthetase
FIV03_12090	COG0489	protein tyrosine kinase activity
FIV03_12130	COG0243	molybdopterin cofactor binding
FIV03_12130	COG3383	formate dehydrogenase (NAD+) activity
FIV03_12135	COG0437	4 iron, 4 sulfur cluster binding
FIV03_12160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV03_12170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_12180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_12185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIV03_12195	COG2986	histidine ammonia-lyase
FIV03_12200	COG1228	amidohydrolase
FIV03_12230	COG0583	DNA-binding transcription factor activity
FIV03_12265	COG0642	Histidine kinase
FIV03_12275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIV03_12280	COG3842	ATPase activity
FIV03_12300	COG1609	Transcriptional regulator
FIV03_12305	COG1629	transport
FIV03_12310	COG3720	iron ion transport
FIV03_12320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_12325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIV03_12330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV03_12355	COG1175	transmembrane transport
FIV03_12370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV03_12410	COG3246	L-lysine catabolic process to acetate
FIV03_12440	COG1086	Polysaccharide biosynthesis protein
FIV03_12445	COG1609	Transcriptional regulator
FIV03_12455	COG1175	transmembrane transport
FIV03_12460	COG0395	ABC-type sugar transport system, permease component
FIV03_12470	COG3842	ATPase activity
FIV03_12490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_12510	COG1024	Enoyl-CoA hydratase
FIV03_12520	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_12535	COG1960	acyl-CoA dehydrogenase activity
FIV03_12540	COG0583	DNA-binding transcription factor activity
FIV03_12545	COG4336	lyase activity
FIV03_12570	COG3932	Exopolysaccharide synthesis, ExoD
FIV03_12585	COG5487	UPF0391 membrane protein
FIV03_12590	COG4325	translation initiation factor activity
FIV03_12605	COG0784	Response regulator, receiver
FIV03_12610	COG3237	CsbD-like
FIV03_12615	COG3920	Histidine kinase
FIV03_12615	COG2202	Pas domain
FIV03_12660	COG0784	Response regulator, receiver
FIV03_12680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIV03_12720	COG0785	Cytochrome C biogenesis protein
FIV03_12730	COG0640	Transcriptional regulator
FIV03_12745	COG2391	methyltransferase activity
FIV03_12785	COG1312	Catalyzes the dehydration of D-mannonate
FIV03_12790	COG0246	Mannitol dehydrogenase
FIV03_12795	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_12805	COG1917	Cupin 2, conserved barrel domain protein
FIV03_12815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV03_12820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_12825	COG1904	glucuronate isomerase
FIV03_12830	COG1802	Transcriptional regulator
FIV03_12835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_12850	COG3971	2-oxopent-4-enoate hydratase activity
FIV03_12855	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_12870	COG3384	dioxygenase
FIV03_12905	COG1215	transferase activity, transferring glycosyl groups
FIV03_12915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_12920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV03_12945	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_12950	COG5441	Belongs to the UPF0261 family
FIV03_12985	COG3842	ATPase activity
FIV03_12995	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV03_13000	COG2204	response regulator
FIV03_13010	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV03_13020	COG5002	protein histidine kinase activity
FIV03_13030	COG2831	hemolysin activation secretion protein
FIV03_13045	COG1846	Transcriptional regulator
FIV03_13105	COG1215	transferase activity, transferring glycosyl groups
FIV03_13105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIV03_13120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV03_13155	COG0300	oxidoreductase activity
FIV03_13170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV03_13180	COG0765	amino acid transport
FIV03_13190	COG2186	Transcriptional regulator
FIV03_13195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIV03_13200	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_13235	COG0482	sulfurtransferase activity
FIV03_13245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIV03_13255	COG1766	The M ring may be actively involved in energy transduction
FIV03_13260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV03_13270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV03_13275	COG2204	response regulator
FIV03_13280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV03_13300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FIV03_13325	COG0494	nUDIX hydrolase
FIV03_13330	COG0435	Glutathione S-transferase
FIV03_13355	COG0714	Associated with various cellular activities
FIV03_13365	COG0494	nUDIX hydrolase
FIV03_13375	COG0617	tRNA 3'-terminal CCA addition
FIV03_13380	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV03_13385	COG0408	coproporphyrinogen oxidase activity
FIV03_13390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIV03_13395	COG1132	(ABC) transporter
FIV03_13405	COG0840	transmembrane signaling receptor activity
FIV03_13420	COG1132	(ABC) transporter
FIV03_13430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIV03_13430	COG2857	Cytochrome c1
FIV03_13435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIV03_13435	COG2857	Cytochrome c1
FIV03_13445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIV03_13450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIV03_13455	COG0778	Nitroreductase
FIV03_13460	COG0456	acetyltransferase
FIV03_13475	COG2345	Transcriptional regulator
FIV03_13490	COG2030	dehydratase
FIV03_13510	COG3273	potassium ion transport
FIV03_13510	COG0471	metal ion transport
FIV03_13515	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_13520	COG0477	Major facilitator Superfamily
FIV03_13525	COG0012	GTP binding
FIV03_13540	COG0193	aminoacyl-tRNA hydrolase activity
FIV03_13545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIV03_13555	COG2258	MOSC domain
FIV03_13570	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_13580	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIV03_13590	COG1744	ABC transporter substrate-binding protein PnrA-like
FIV03_13595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIV03_13605	COG0006	proline dipeptidase activity
FIV03_13620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIV03_13640	COG3685	Protein conserved in bacteria
FIV03_13650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV03_13660	COG2205	protein histidine kinase activity
FIV03_13665	COG0745	RESPONSE REGULATOR receiver
FIV03_13670	COG1846	Transcriptional regulator
FIV03_13690	COG2814	Major facilitator Superfamily
FIV03_13695	COG0314	molybdopterin synthase activity
FIV03_13705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIV03_13715	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIV03_13725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV03_13730	COG4977	sequence-specific DNA binding
FIV03_13730	COG1917	Cupin 2, conserved barrel domain protein
FIV03_13735	COG1970	mechanosensitive ion channel activity
FIV03_13740	COG1435	thymidine kinase activity
FIV03_13750	COG0457	Tetratricopeptide repeat
FIV03_13755	COG0457	Tetratricopeptide repeat
FIV03_13760	COG0322	excinuclease ABC activity
FIV03_13785	COG0667	Aldo Keto reductase
FIV03_13800	COG2192	nodulation
FIV03_13820	COG3842	ATPase activity
FIV03_13825	COG1178	ABC-type Fe3 transport system permease component
FIV03_13830	COG1349	DNA-binding transcription factor activity
FIV03_13835	COG3852	Histidine kinase
FIV03_13900	COG0625	glutathione transferase activity
FIV03_13915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIV03_13925	COG1278	Cold shock
FIV03_13935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV03_13950	COG5001	Diguanylate cyclase
FIV03_13950	COG3300	MHYT domain
FIV03_13955	COG2211	Major facilitator Superfamily
FIV03_13965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIV03_14000	COG2885	chlorophyll binding
FIV03_14010	COG2827	Endonuclease containing a URI domain
FIV03_14015	COG0556	nucleotide-excision repair
FIV03_14045	COG3119	arylsulfatase activity
FIV03_14050	COG0747	negative chemotaxis
FIV03_14065	COG1309	transcriptional regulator
FIV03_14070	COG0789	Transcriptional regulator
FIV03_14080	COG0840	transmembrane signaling receptor activity
FIV03_14150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIV03_14155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIV03_14160	COG0583	DNA-binding transcription factor activity
FIV03_14165	COG0492	ferredoxin-NADP+ reductase activity
FIV03_14175	COG1522	sequence-specific DNA binding
FIV03_14190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV03_14195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIV03_14205	COG0789	Transcriptional regulator
FIV03_14210	COG0505	Belongs to the CarA family
FIV03_14225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV03_14250	COG2271	Major facilitator Superfamily
FIV03_14260	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FIV03_14285	COG1309	transcriptional regulator
FIV03_14290	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_14300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIV03_14310	COG1024	Enoyl-CoA hydratase
FIV03_14315	COG1309	transcriptional regulator
FIV03_14320	COG1802	Transcriptional regulator
FIV03_14325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_14350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV03_14360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_14370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_14375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV03_14380	COG1309	transcriptional regulator
FIV03_14425	COG0628	permease
FIV03_14470	COG1473	amidohydrolase
FIV03_14480	COG4215	(ABC) transporter
FIV03_14485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV03_14495	COG1309	transcriptional regulator
FIV03_14510	COG2205	protein histidine kinase activity
FIV03_14510	COG3437	response regulator, receiver
FIV03_14510	COG3850	Histidine kinase
FIV03_14510	COG4999	Histidine kinase
FIV03_14515	COG2197	response regulator
FIV03_14530	COG2304	oxidoreductase activity
FIV03_14545	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_14545	COG0824	Thioesterase
FIV03_14550	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_14555	COG3246	L-lysine catabolic process to acetate
FIV03_14570	COG1960	acyl-CoA dehydrogenase activity
FIV03_14595	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV03_14680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_14695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV03_14725	COG4977	sequence-specific DNA binding
FIV03_14875	COG3772	lysozyme
FIV03_14895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV03_14905	COG1280	lysine exporter protein (LysE YggA)
FIV03_14935	COG0840	transmembrane signaling receptor activity
FIV03_14985	COG0431	NADPH-dependent FMN reductase
FIV03_14990	COG5001	Diguanylate cyclase
FIV03_14990	COG3300	MHYT domain
FIV03_14995	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIV03_15000	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIV03_15025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIV03_15060	COG2001	Belongs to the MraZ family
FIV03_15065	COG0275	rRNA processing
FIV03_15080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIV03_15090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV03_15095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIV03_15105	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIV03_15110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIV03_15120	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV03_15125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIV03_15130	COG0849	cell division
FIV03_15135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIV03_15145	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV03_15150	COG0497	DNA recombination
FIV03_15170	COG0210	DNA helicase
FIV03_15190	COG0006	proline dipeptidase activity
FIV03_15190	COG0006	proline dipeptidase activity
FIV03_15200	COG0038	chloride channel
FIV03_15205	COG0038	chloride channel
FIV03_15215	COG0277	FAD linked oxidase domain protein
FIV03_15240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIV03_15280	COG0330	HflC and HflK could
FIV03_15285	COG0330	HflC and HflK could
FIV03_15305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIV03_15335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV03_15365	COG0640	Transcriptional regulator
FIV03_15375	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_15380	COG2207	Transcriptional regulator
FIV03_15385	COG0384	phenazine biosynthesis protein PhzF
FIV03_15395	COG1741	Belongs to the pirin family
FIV03_15400	COG1131	(ABC) transporter
FIV03_15405	COG0454	-acetyltransferase
FIV03_15405	COG0456	acetyltransferase
FIV03_15410	COG0842	Transport permease protein
FIV03_15415	COG1686	Belongs to the peptidase S11 family
FIV03_15420	COG3706	GGDEF domain
FIV03_15425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIV03_15445	COG0583	DNA-binding transcription factor activity
FIV03_15465	COG0693	protein deglycase activity
FIV03_15475	COG2943	transferase activity, transferring hexosyl groups
FIV03_15485	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FIV03_15490	COG0579	oxidoreductase
FIV03_15495	COG0154	amidase activity
FIV03_15505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIV03_15530	COG2375	cellular response to nickel ion
FIV03_15545	COG1522	sequence-specific DNA binding
FIV03_15550	COG0523	cobalamin synthesis protein
FIV03_15565	COG1280	lysine exporter protein (LysE YggA)
FIV03_15575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIV03_15585	COG3011	Protein conserved in bacteria
FIV03_15590	COG3706	GGDEF domain
FIV03_15595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIV03_15610	COG0440	acetolactate synthase activity
FIV03_15615	COG0028	Belongs to the TPP enzyme family
FIV03_15875	COG0840	transmembrane signaling receptor activity
FIV03_15905	COG1522	sequence-specific DNA binding
FIV03_15910	COG0686	Belongs to the AlaDH PNT family
FIV03_15955	COG3237	CsbD-like
FIV03_15965	COG0129	dihydroxy-acid dehydratase activity
FIV03_15970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIV03_16005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIV03_16020	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_16035	COG0697	spore germination
FIV03_16045	COG0189	ligase activity
FIV03_16045	COG4067	protein conserved in archaea
FIV03_16050	COG0189	ligase activity
FIV03_16055	COG2226	methyltransferase
FIV03_16065	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FIV03_16085	COG4974	Belongs to the 'phage' integrase family
FIV03_16115	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIV03_16140	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FIV03_16145	COG0351	phosphomethylpyrimidine kinase
FIV03_16150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_16170	COG0438	transferase activity, transferring glycosyl groups
FIV03_16190	COG2814	Major facilitator Superfamily
FIV03_16195	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_16205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV03_16210	COG1127	ABC transporter
FIV03_16230	COG0300	oxidoreductase activity
FIV03_16245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_16275	COG0633	Ferredoxin
FIV03_16295	COG0589	response to stress
FIV03_16330	COG3768	UPF0283 membrane protein
FIV03_16335	COG3106	COG3106 Predicted ATPase
FIV03_16350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV03_16355	COG1749	Flagellar hook protein flgE
FIV03_16395	COG5443	negative regulation of bacterial-type flagellum assembly
FIV03_16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV03_16425	COG3951	Flagellar rod assembly protein muramidase FlgJ
FIV03_16430	COG1706	bacterial-type flagellum-dependent cell motility
FIV03_16445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIV03_16450	COG0737	Belongs to the 5'-nucleotidase family
FIV03_16465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV03_16470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIV03_16480	COG4786	Flagellar basal body rod
FIV03_16485	COG4786	Flagellar basal body rod
FIV03_16525	COG1338	Plays a role in the flagellum-specific transport system
FIV03_16535	COG1815	bacterial-type flagellum-dependent cell motility
FIV03_16540	COG1558	bacterial-type flagellum-dependent cell motility
FIV03_16545	COG1677	Flagellar hook-basal body complex protein FliE
FIV03_16550	COG1987	bacterial-type flagellum assembly
FIV03_16555	COG1684	flagellar biosynthetic protein fliR
FIV03_16560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV03_16595	COG4589	Belongs to the CDS family
FIV03_16600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIV03_16615	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIV03_16625	COG1960	acyl-CoA dehydrogenase activity
FIV03_16630	COG0583	DNA-binding transcription factor activity
FIV03_16640	COG3738	Protein conserved in bacteria
FIV03_16650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV03_16655	COG2197	response regulator
FIV03_16660	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_16665	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_16675	COG1335	isochorismatase
FIV03_16690	COG1309	transcriptional regulator
FIV03_16745	COG0625	glutathione transferase activity
FIV03_16765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_16770	COG0601	transmembrane transport
FIV03_16775	COG1652	LysM domain
FIV03_16780	COG0697	spore germination
FIV03_16795	COG0640	Transcriptional regulator
FIV03_16805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_16810	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_16825	COG0435	Glutathione S-transferase
FIV03_16860	COG1132	(ABC) transporter
FIV03_16875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIV03_16880	COG3383	formate dehydrogenase (NAD+) activity
FIV03_16895	COG0583	DNA-binding transcription factor activity
FIV03_16940	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIV03_16940	COG3264	Mechanosensitive ion channel
FIV03_16945	COG2313	pseudouridylate synthase activity
FIV03_16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_16990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV03_17005	COG0390	transport system, permease component
FIV03_17010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV03_17015	COG0538	isocitrate dehydrogenase activity
FIV03_17025	COG0477	Major facilitator Superfamily
FIV03_17030	COG5001	Diguanylate cyclase
FIV03_17035	COG1605	Chorismate mutase
FIV03_17060	COG2207	Transcriptional regulator
FIV03_17070	COG1846	Transcriptional regulator
FIV03_17090	COG3300	MHYT domain
FIV03_17090	COG5001	Diguanylate cyclase
FIV03_17110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIV03_17115	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIV03_17125	COG1652	LysM domain
FIV03_17145	COG0583	DNA-binding transcription factor activity
FIV03_17150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV03_17170	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_17185	COG4952	isomerase
FIV03_17190	COG3347	Dehydrogenase
FIV03_17190	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_17200	COG1879	ABC-type sugar transport system periplasmic component
FIV03_17205	COG1129	ABC transporter
FIV03_17210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_17215	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_17220	COG3254	rhamnose metabolic process
FIV03_17230	COG0037	tRNA processing
FIV03_17235	COG0583	DNA-binding transcription factor activity
FIV03_17250	COG1388	LysM domain
FIV03_17250	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_17280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIV03_17290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV03_17315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV03_17330	COG1917	Cupin 2, conserved barrel domain protein
FIV03_17330	COG4977	sequence-specific DNA binding
FIV03_17340	COG0047	phosphoribosylformylglycinamidine synthase activity
FIV03_17345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV03_17355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIV03_17395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIV03_17405	COG0531	amino acid
FIV03_17430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_17435	COG1522	sequence-specific DNA binding
FIV03_17455	COG0668	transmembrane transport
FIV03_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV03_17480	COG1126	abc transporter atp-binding protein
FIV03_17500	COG0646	methionine synthase
FIV03_17500	COG1410	methionine synthase
FIV03_17545	COG0745	RESPONSE REGULATOR receiver
FIV03_17575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIV03_17580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_17585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_17590	COG1120	ATPase activity
FIV03_17610	COG0745	RESPONSE REGULATOR receiver
FIV03_17615	COG5002	protein histidine kinase activity
FIV03_17620	COG0583	DNA-binding transcription factor activity
FIV03_17625	COG0625	glutathione transferase activity
FIV03_17630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV03_17630	COG1017	nitric oxide dioxygenase activity
FIV03_17650	COG5310	Homospermidine synthase
FIV03_17675	COG0659	secondary active sulfate transmembrane transporter activity
FIV03_17700	COG0436	Aminotransferase
FIV03_17730	COG1309	transcriptional regulator
FIV03_17740	COG1703	isobutyryl-CoA mutase activity
FIV03_17765	COG0668	transmembrane transport
FIV03_17775	COG0433	COG0433 Predicted ATPase
FIV03_17815	COG3655	Transcriptional regulator
FIV03_17835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_17845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_17860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV03_17865	COG0477	Major facilitator Superfamily
FIV03_17870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIV03_17880	COG2010	Cytochrome c
FIV03_17890	COG0251	oxidation-reduction process
FIV03_17905	COG0583	DNA-binding transcription factor activity
FIV03_17930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIV03_17940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_17955	COG0702	epimerase
FIV03_17960	COG1733	regulation of RNA biosynthetic process
FIV03_17970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV03_17985	COG2111	Na H antiporter
FIV03_17990	COG1006	Multisubunit Na H antiporter MnhC subunit
FIV03_18005	COG2212	antiporter activity
FIV03_18010	COG1320	monovalent cation:proton antiporter activity
FIV03_18020	COG2166	iron-sulfur cluster assembly
FIV03_18060	COG0457	Tetratricopeptide repeat
FIV03_18075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIV03_18080	COG2983	Belongs to the UPF0260 family
FIV03_18095	COG0741	lytic transglycosylase activity
FIV03_18120	COG2353	YceI-like domain
FIV03_18125	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_18150	COG5425	PFAM Usg family protein
FIV03_18165	COG0142	geranyltranstransferase activity
FIV03_18170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIV03_18180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV03_18180	COG0574	Belongs to the PEP-utilizing enzyme family
FIV03_18190	COG5001	Diguanylate cyclase
FIV03_18190	COG3300	MHYT domain
FIV03_18195	COG2003	Belongs to the UPF0758 family
FIV03_18200	COG0024	Methionine aminopeptidase
FIV03_18210	COG3454	Phosphonate metabolism
FIV03_18215	COG3639	organic phosphonate transmembrane transporter activity
FIV03_18220	COG3639	organic phosphonate transmembrane transporter activity
FIV03_18230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV03_18240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV03_18245	COG3639	organic phosphonate transmembrane transporter activity
FIV03_18255	COG1363	Peptidase, m42
FIV03_18265	COG0367	asparagine synthase
FIV03_18270	COG1846	Transcriptional regulator
FIV03_18275	COG3300	MHYT domain
FIV03_18275	COG5001	Diguanylate cyclase
FIV03_18280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV03_18285	COG1489	DNA binding
FIV03_18290	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_18295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIV03_18300	COG1058	Belongs to the CinA family
FIV03_18300	COG1546	Belongs to the CinA family
FIV03_18305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV03_18325	COG1024	Enoyl-CoA hydratase
FIV03_18375	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FIV03_18380	COG3005	denitrification pathway
FIV03_18385	COG3043	anaerobic respiration
FIV03_18390	COG0243	molybdopterin cofactor binding
FIV03_18400	COG4459	periplasmic nitrate reductase
FIV03_18405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIV03_18410	COG0302	gtp cyclohydrolase
FIV03_18420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIV03_18425	COG1032	radical SAM domain protein
FIV03_18435	COG1522	sequence-specific DNA binding
FIV03_18440	COG0456	acetyltransferase
FIV03_18445	COG0189	ligase activity
FIV03_18450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIV03_18470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIV03_18505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIV03_18510	COG3591	Belongs to the peptidase S1B family
FIV03_18520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV03_18545	COG3707	response regulator
FIV03_18550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_18550	COG1116	anion transmembrane transporter activity
FIV03_18555	COG1116	anion transmembrane transporter activity
FIV03_18555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_18565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_18565	COG1116	anion transmembrane transporter activity
FIV03_18570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV03_18590	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FIV03_18595	COG0243	molybdopterin cofactor binding
FIV03_18600	COG1648	precorrin-2 dehydrogenase activity
FIV03_18600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV03_18605	COG1802	Transcriptional regulator
FIV03_18640	COG4608	Belongs to the ABC transporter superfamily
FIV03_18645	COG0444	Belongs to the ABC transporter superfamily
FIV03_18650	COG0601	transmembrane transport
FIV03_18655	COG0747	negative chemotaxis
FIV03_18665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIV03_18670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIV03_18675	COG1845	cytochrome c oxidase, subunit III
FIV03_18680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIV03_18690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIV03_18735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV03_18755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIV03_18760	COG0081	regulation of translation
FIV03_18765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIV03_18770	COG0222	ribosome binding
FIV03_18775	COG0085	RNA polymerase activity
FIV03_18790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIV03_18795	COG0049	tRNA binding
FIV03_18800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIV03_18805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV03_18810	COG0051	transcription antitermination factor activity, RNA binding
FIV03_18815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIV03_18820	COG0088	Forms part of the polypeptide exit tunnel
FIV03_18825	COG0089	rRNA binding
FIV03_18830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIV03_18840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIV03_18845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIV03_18850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIV03_18860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIV03_18865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIV03_18870	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIV03_18875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIV03_18880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIV03_18885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIV03_18900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIV03_18905	COG1841	ribosomal large subunit assembly
FIV03_18910	COG0200	Binds to the 23S rRNA
FIV03_18915	COG0201	protein transport
FIV03_18920	COG0563	adenylate kinase activity
FIV03_18925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIV03_18930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIV03_18935	COG0202	RNA polymerase activity
FIV03_18940	COG0203	ribosomal protein L17
FIV03_18945	COG0840	transmembrane signaling receptor activity
FIV03_18955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIV03_18965	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV03_18985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIV03_18990	COG0564	pseudouridine synthase activity
FIV03_19010	COG0546	phosphoglycolate phosphatase activity
FIV03_19020	COG2239	Acts as a magnesium transporter
FIV03_19030	COG1305	Transglutaminase-like
FIV03_19040	COG2308	Evidence 4 Homologs of previously reported genes of
FIV03_19050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV03_19085	COG0697	spore germination
FIV03_19090	COG1254	Belongs to the acylphosphatase family
FIV03_19115	COG0321	lipoyl(octanoyl) transferase activity
FIV03_19120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV03_19145	COG2239	Acts as a magnesium transporter
FIV03_19165	COG1846	Transcriptional regulator
FIV03_19170	COG1764	response to oxidative stress
FIV03_19205	COG1960	acyl-CoA dehydrogenase activity
FIV03_19220	COG1309	transcriptional regulator
FIV03_19245	COG0740	serine-type endopeptidase activity
FIV03_19255	COG0745	RESPONSE REGULATOR receiver
FIV03_19255	COG3706	GGDEF domain
FIV03_19315	COG0484	heat shock protein binding
FIV03_19320	COG1686	Belongs to the peptidase S11 family
FIV03_19330	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIV03_19340	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_19365	COG0537	adenosine 5'-monophosphoramidase activity
FIV03_19380	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_19380	COG0204	Acyl-transferase
FIV03_19410	COG1309	transcriptional regulator
FIV03_19465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV03_19480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV03_19510	COG0511	ligase activity, forming carbon-carbon bonds
FIV03_19530	COG1530	ribonuclease E activity
FIV03_19535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIV03_19540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIV03_19550	COG0739	heme binding
FIV03_19555	COG2833	Protein of unknown function (DUF455)
FIV03_19560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIV03_19570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIV03_19590	COG0174	glutamine synthetase
FIV03_19595	COG0347	Belongs to the P(II) protein family
FIV03_19605	COG3920	Histidine kinase
FIV03_19605	COG2202	Pas domain
FIV03_19615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIV03_19615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIV03_19625	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIV03_19630	COG0740	serine-type endopeptidase activity
FIV03_19635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIV03_19640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIV03_19655	COG1231	oxidoreductase activity
FIV03_19680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV03_19685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV03_19690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV03_19700	COG0649	NAD binding
FIV03_19710	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIV03_19720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIV03_19730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV03_19740	COG0713	ATP synthesis coupled electron transport
FIV03_19755	COG1007	ATP synthesis coupled electron transport
FIV03_19780	COG0442	prolyl-tRNA aminoacylation
FIV03_19790	COG1136	(ABC) transporter
FIV03_19800	COG0587	DNA-directed DNA polymerase activity
FIV03_19810	COG0747	negative chemotaxis
FIV03_19835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV03_19840	COG0662	Cupin 2, conserved barrel domain protein
FIV03_19850	COG0052	Belongs to the universal ribosomal protein uS2 family
FIV03_19855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIV03_19860	COG0528	UMP kinase activity
FIV03_19865	COG0233	cytoplasmic translational termination
FIV03_19880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIV03_19885	COG0750	zinc metalloprotease
FIV03_19890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV03_19895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV03_19900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIV03_19905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV03_19915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV03_19920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV03_19940	COG0840	transmembrane signaling receptor activity
FIV03_19945	COG0372	Belongs to the citrate synthase family
FIV03_19950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV03_19955	COG0658	competence protein
FIV03_19955	COG2333	competence protein COMEC
FIV03_19960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIV03_19980	COG0114	fumarate hydratase activity
FIV03_19990	COG1802	Transcriptional regulator
FIV03_20010	COG1558	bacterial-type flagellum-dependent cell motility
FIV03_20015	COG1677	Flagellar hook-basal body complex protein FliE
FIV03_20020	COG4786	Flagellar basal body rod
FIV03_20025	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FIV03_20030	COG1706	bacterial-type flagellum-dependent cell motility
FIV03_20050	COG1338	Plays a role in the flagellum-specific transport system
FIV03_20055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV03_20105	COG5442	Flagellar protein FlaF
FIV03_20110	COG5443	negative regulation of bacterial-type flagellum assembly
FIV03_20115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIV03_20125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV03_20130	COG1684	flagellar biosynthetic protein fliR
FIV03_20170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV03_20175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV03_20180	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV03_20195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIV03_20205	COG4786	Flagellar basal body rod
FIV03_20215	COG1157	protein secretion by the type III secretion system
FIV03_20225	COG4191	Histidine kinase
FIV03_20225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV03_20260	COG0315	cyclic pyranopterin monophosphate synthase activity
FIV03_20275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV03_20280	COG0149	triose-phosphate isomerase activity
FIV03_20290	COG0504	CTP synthase activity
FIV03_20325	COG0785	Cytochrome C biogenesis protein
FIV03_20335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV03_20340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV03_20350	COG2832	Protein of unknown function (DUF454)
FIV03_20360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIV03_20365	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIV03_20370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIV03_20375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIV03_20385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIV03_20390	COG0022	dehydrogenase e1 component
FIV03_20390	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV03_20395	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV03_20400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV03_20420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIV03_20425	COG2867	negative regulation of translational initiation
FIV03_20445	COG1058	Belongs to the CinA family
FIV03_20445	COG1546	Belongs to the CinA family
FIV03_20450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIV03_20450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIV03_20460	COG3852	Histidine kinase
FIV03_20465	COG2204	response regulator
FIV03_20470	COG5000	phosphorelay sensor kinase activity
FIV03_20475	COG2204	response regulator
FIV03_20480	COG0569	domain protein
FIV03_20485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV03_20490	COG1923	regulation of RNA biosynthetic process
FIV03_20495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIV03_20500	COG3956	TIGRFAM MazG family protein
FIV03_20505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_20510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_20515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FIV03_20540	COG1309	transcriptional regulator
FIV03_20570	COG2137	regulation of response to DNA damage stimulus
FIV03_20580	COG0084	hydrolase, TatD family'
FIV03_20585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIV03_20595	COG1686	Belongs to the peptidase S11 family
FIV03_20610	COG3279	Response regulator of the LytR AlgR family
FIV03_20630	COG0542	response to heat
FIV03_20640	COG3608	succinylglutamate desuccinylase aspartoacylase
FIV03_20640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIV03_20660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_20665	COG1116	anion transmembrane transporter activity
FIV03_20670	COG0010	Belongs to the arginase family
FIV03_20690	COG5001	Diguanylate cyclase
FIV03_20700	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV03_20730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV03_20745	COG0583	DNA-binding transcription factor activity
FIV03_20755	COG1183	phosphatidylcholine synthase activity
FIV03_20765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV03_20775	COG0679	Auxin Efflux Carrier
FIV03_20785	COG2301	Belongs to the HpcH HpaI aldolase family
FIV03_20820	COG0148	phosphopyruvate hydratase activity
FIV03_20830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIV03_20845	COG0343	queuine tRNA-ribosyltransferase activity
FIV03_20850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIV03_20855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV03_20860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV03_20875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIV03_20880	COG2095	MarC family integral membrane protein
FIV03_20890	COG1733	regulation of RNA biosynthetic process
FIV03_20915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIV03_20915	COG0519	Catalyzes the synthesis of GMP from XMP
FIV03_20925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIV03_20925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIV03_20935	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIV03_20940	COG0248	Ppx GppA phosphatase
FIV03_20955	COG3962	Belongs to the TPP enzyme family
FIV03_20960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_20970	COG0673	inositol 2-dehydrogenase activity
FIV03_20980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV03_20990	COG3622	Belongs to the hyi family
FIV03_21005	COG1082	Xylose isomerase domain protein TIM barrel
FIV03_21010	COG0673	inositol 2-dehydrogenase activity
FIV03_21015	COG1129	ABC transporter
FIV03_21020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_21055	COG1609	Transcriptional regulator
FIV03_21090	COG1802	Transcriptional regulator
FIV03_21100	COG0006	proline dipeptidase activity
FIV03_21105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIV03_21110	COG2423	ornithine cyclodeaminase activity
FIV03_21115	COG1522	sequence-specific DNA binding
FIV03_21120	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_21125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_21135	COG1132	(ABC) transporter
FIV03_21150	COG1024	Enoyl-CoA hydratase
FIV03_21155	COG2050	protein possibly involved in aromatic compounds catabolism
FIV03_21165	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_21165	COG2030	dehydratase
FIV03_21170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV03_21175	COG2151	metal-sulfur cluster biosynthetic enzyme
FIV03_21180	COG3396	Phenylacetate-CoA oxygenase
FIV03_21185	COG3460	Phenylacetate-CoA oxygenase
FIV03_21195	COG3396	Phenylacetate-CoA oxygenase
FIV03_21210	COG2989	Protein conserved in bacteria
FIV03_21220	COG0629	single-stranded DNA binding
FIV03_21225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIV03_21250	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIV03_21270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV03_21290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIV03_21300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIV03_21305	COG0805	protein transport
FIV03_21310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV03_21315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV03_21320	COG3842	ATPase activity
FIV03_21325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIV03_21330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIV03_21335	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV03_21350	COG0583	DNA-binding transcription factor activity
FIV03_21360	COG0018	arginyl-trna synthetase
FIV03_21365	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIV03_21370	COG0316	Belongs to the HesB IscA family
FIV03_21385	COG0187	DNA topoisomerase II activity
FIV03_21395	COG0513	Belongs to the DEAD box helicase family
FIV03_21400	COG0745	RESPONSE REGULATOR receiver
FIV03_21400	COG3706	GGDEF domain
FIV03_21405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIV03_21410	COG0316	Belongs to the HesB IscA family
FIV03_21415	COG2151	metal-sulfur cluster biosynthetic enzyme
FIV03_21420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV03_21425	COG0719	Fe-S assembly protein
FIV03_21430	COG0396	ATPase activity
FIV03_21440	COG0719	Fe-S assembly protein
FIV03_21445	COG1104	cysteine desulfurase activity
FIV03_21450	COG2945	thiolester hydrolase activity
FIV03_21470	COG0525	valine-tRNA ligase activity
FIV03_21490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIV03_21505	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV03_21525	COG1492	cobalamin metabolic process
FIV03_21565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIV03_21570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV03_21575	COG2188	Transcriptional regulator
FIV03_21580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIV03_21590	COG3142	Participates in the control of copper homeostasis
FIV03_21605	COG0395	ABC-type sugar transport system, permease component
FIV03_21615	COG3842	ATPase activity
FIV03_21640	COG1737	Transcriptional regulator
FIV03_21645	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_21675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV03_21680	COG0300	oxidoreductase activity
FIV03_21695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIV03_21700	COG1280	lysine exporter protein (LysE YggA)
FIV03_21720	COG3791	Glutathione-dependent formaldehyde-activating
FIV03_21725	COG2897	thiosulfate sulfurtransferase activity
FIV03_21740	COG1309	transcriptional regulator
FIV03_21750	COG1126	abc transporter atp-binding protein
FIV03_21755	COG0765	amino acid transport
FIV03_21760	COG4597	amino acid ABC transporter
FIV03_21765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV03_21770	COG0626	cystathionine gamma-synthase activity
FIV03_21780	COG0463	Glycosyl transferase, family 2
FIV03_21785	COG0671	phosphoesterase, PA-phosphatase related
FIV03_21795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIV03_21870	COG1278	Cold shock
FIV03_21875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIV03_21915	COG0811	peptide transport
FIV03_21950	COG2885	chlorophyll binding
FIV03_21970	COG3501	Rhs element vgr protein
FIV03_22025	COG0739	heme binding
FIV03_22025	COG0741	lytic transglycosylase activity
FIV03_22025	COG1196	nuclear chromosome segregation
FIV03_22060	COG2423	ornithine cyclodeaminase activity
FIV03_22065	COG0387	Pfam Sodium calcium exchanger
FIV03_22070	COG0410	ABC transporter
FIV03_22075	COG1129	ABC transporter
FIV03_22085	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_22100	COG0339	signal peptide processing
FIV03_22110	COG2124	cytochrome p450
FIV03_22120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIV03_22125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIV03_22140	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV03_22140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIV03_22150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV03_22160	COG0306	phosphate transporter
FIV03_22170	COG0306	phosphate transporter
FIV03_22190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIV03_22195	COG1494	fructose-1,6-bisphosphatase
FIV03_22205	COG0436	Aminotransferase
FIV03_22210	COG2199	diguanylate cyclase activity
FIV03_22220	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIV03_22240	COG0010	Belongs to the arginase family
FIV03_22250	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_22260	COG0789	Transcriptional regulator
FIV03_22270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIV03_22295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV03_22300	COG0646	methionine synthase
FIV03_22300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIV03_22305	COG5598	trimethylamine methyltransferase
FIV03_22315	COG0156	8-amino-7-oxononanoate synthase activity
FIV03_22345	COG2942	2-epimerase
FIV03_22350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIV03_22375	COG5001	Diguanylate cyclase
FIV03_22395	COG2353	YceI-like domain
FIV03_22400	COG3038	cytochrome b561
FIV03_22410	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIV03_22410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FIV03_22415	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_22420	COG1309	transcriptional regulator
FIV03_22445	COG0415	Belongs to the DNA photolyase family
FIV03_22450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIV03_22455	COG2814	Major facilitator Superfamily
FIV03_22460	COG0489	protein tyrosine kinase activity
FIV03_22480	COG3135	benzoate transporter
FIV03_22485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIV03_22490	COG0746	molybdenum cofactor guanylyltransferase activity
FIV03_22495	COG1763	Mo-molybdopterin cofactor biosynthetic process
FIV03_22500	COG0303	'Molybdopterin
FIV03_22505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIV03_22510	COG0583	DNA-binding transcription factor activity
FIV03_22515	COG0625	glutathione transferase activity
FIV03_22540	COG0626	cystathionine gamma-synthase activity
FIV03_22545	COG0583	DNA-binding transcription factor activity
FIV03_22555	COG2084	Dehydrogenase
FIV03_22575	COG4638	Rieske (2fe-2S)
FIV03_22585	COG1902	pentaerythritol trinitrate reductase activity
FIV03_22585	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV03_22605	COG1522	sequence-specific DNA binding
FIV03_22615	COG1573	uracil-dna glycosylase
FIV03_22620	COG2205	protein histidine kinase activity
FIV03_22620	COG2202	Pas domain
FIV03_22625	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIV03_22630	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIV03_22645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIV03_22680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV03_22710	COG0697	spore germination
FIV03_22715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_22720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_22740	COG1294	oxidase, subunit
FIV03_22745	COG1271	oxidase subunit
FIV03_22755	COG4988	ABC transporter
FIV03_22775	COG0583	DNA-binding transcription factor activity
FIV03_22805	COG1741	Belongs to the pirin family
FIV03_22815	COG0235	Class ii aldolase
FIV03_22820	COG1940	carbohydrate kinase activity
FIV03_22830	COG1846	Transcriptional regulator
FIV03_22850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV03_22850	COG0512	Glutamine amidotransferase of anthranilate synthase
FIV03_22870	COG3300	MHYT domain
FIV03_22870	COG5001	Diguanylate cyclase
FIV03_22880	COG0129	dihydroxy-acid dehydratase activity
FIV03_22895	COG1902	pentaerythritol trinitrate reductase activity
FIV03_22900	COG1309	transcriptional regulator
FIV03_22925	COG3119	arylsulfatase activity
FIV03_22940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV03_22960	COG0540	Belongs to the ATCase OTCase family
FIV03_22965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIV03_22975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIV03_22980	COG0758	DNA mediated transformation
FIV03_22985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV03_22990	COG0557	exoribonuclease II activity
FIV03_23030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV03_23055	COG0456	acetyltransferase
FIV03_23065	COG0583	DNA-binding transcription factor activity
FIV03_23080	COG3257	ureidoglycine aminohydrolase activity
FIV03_23085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV03_23100	COG2200	EAL domain
FIV03_23105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_23115	COG1132	(ABC) transporter
FIV03_23120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIV03_23125	COG0489	protein tyrosine kinase activity
FIV03_23130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIV03_23140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIV03_23150	COG0628	permease
FIV03_23155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIV03_23160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIV03_23175	COG1120	ATPase activity
FIV03_23180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_23190	COG2226	methyltransferase
FIV03_23200	COG2186	Transcriptional regulator
FIV03_23205	COG3842	ATPase activity
FIV03_23215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV03_23245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_23260	COG4172	Belongs to the ABC transporter superfamily
FIV03_23265	COG2354	Protein conserved in bacteria
FIV03_23270	COG0519	Catalyzes the synthesis of GMP from XMP
FIV03_23285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV03_23295	COG0243	molybdopterin cofactor binding
FIV03_23310	COG0105	UTP biosynthetic process
FIV03_23330	COG0488	(ABC) transporter
FIV03_23350	COG2927	DNA polymerase III (CHI subunit)
FIV03_23360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIV03_23380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV03_23385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIV03_23390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIV03_23405	COG0194	GDP metabolic process
FIV03_23410	COG1561	YicC-like family, N-terminal region
FIV03_23415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIV03_23420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIV03_23425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV03_23435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIV03_23445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIV03_23455	COG0305	Participates in initiation and elongation during chromosome replication
FIV03_23465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV03_23475	COG1286	toxin biosynthetic process
FIV03_23480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIV03_23485	COG4221	oxidoreductase activity
FIV03_23505	COG1160	GTP binding
FIV03_23510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV03_23530	COG0735	belongs to the Fur family
FIV03_23535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV03_23540	COG1121	(ABC) transporter
FIV03_23570	COG1695	Transcriptional regulator
FIV03_23595	COG1183	phosphatidylcholine synthase activity
FIV03_23600	COG0688	phosphatidylethanolamine metabolic process
FIV03_23605	COG0583	DNA-binding transcription factor activity
FIV03_23615	COG5265	(ABC) transporter
FIV03_23625	COG1652	LysM domain
FIV03_23635	COG0745	RESPONSE REGULATOR receiver
FIV03_23635	COG3706	GGDEF domain
FIV03_23645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV03_23665	COG0215	cysteine-tRNA ligase activity
FIV03_23670	COG2989	Protein conserved in bacteria
FIV03_23680	COG0640	Transcriptional regulator
FIV03_23700	COG3045	CreA protein
FIV03_23725	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FIV03_23725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV03_23745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIV03_23760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV03_23770	COG3447	MASE1 domain protein
FIV03_23770	COG5002	protein histidine kinase activity
FIV03_23770	COG5001	Diguanylate cyclase
FIV03_23785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIV03_23790	COG0840	transmembrane signaling receptor activity
FIV03_23795	COG0546	phosphoglycolate phosphatase activity
FIV03_23975	COG0464	growth
FIV03_23985	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIV03_24095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV03_24100	COG1083	cytidylyl-transferase
FIV03_24110	COG2089	acid synthase
FIV03_24145	COG3214	Protein conserved in bacteria
FIV03_24165	COG1063	alcohol dehydrogenase
FIV03_24170	COG0156	8-amino-7-oxononanoate synthase activity
FIV03_24175	COG1280	lysine exporter protein (LysE YggA)
FIV03_24200	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIV03_24210	COG1309	transcriptional regulator
FIV03_24215	COG5012	cobalamin binding
FIV03_24230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIV03_24235	COG1410	methionine synthase
FIV03_24235	COG0646	methionine synthase
FIV03_24260	COG1832	CoA-binding protein
FIV03_24285	COG1612	heme a metabolic process
FIV03_24355	COG0438	transferase activity, transferring glycosyl groups
FIV03_24355	COG1216	Glycosyl transferase, family 2
FIV03_24365	COG1091	dTDP-4-dehydrorhamnose reductase activity
FIV03_24370	COG1088	dTDP-glucose 4,6-dehydratase activity
FIV03_24375	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FIV03_24385	COG0747	negative chemotaxis
FIV03_24395	COG0601	transmembrane transport
FIV03_24405	COG0444	Belongs to the ABC transporter superfamily
FIV03_24410	COG4608	Belongs to the ABC transporter superfamily
FIV03_24430	COG2124	cytochrome p450
FIV03_24450	COG0776	regulation of translation
FIV03_24455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV03_24460	COG0416	fatty acid biosynthetic process
FIV03_24480	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FIV03_24485	COG2814	Major facilitator Superfamily
FIV03_24490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIV03_24500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIV03_24510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIV03_24510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIV03_24515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIV03_24520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIV03_24530	COG2989	Protein conserved in bacteria
FIV03_24535	COG1846	Transcriptional regulator
FIV03_24550	COG1024	Enoyl-CoA hydratase
FIV03_24555	COG1960	acyl-CoA dehydrogenase activity
FIV03_24560	COG0113	porphobilinogen synthase activity
FIV03_24565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIV03_24575	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FIV03_24580	COG0471	metal ion transport
FIV03_24580	COG3273	potassium ion transport
FIV03_24585	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIV03_24590	COG1573	uracil-dna glycosylase
FIV03_24600	COG1758	RNA polymerase activity
FIV03_24610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIV03_24620	COG0736	holo-[acyl-carrier-protein] synthase activity
FIV03_24625	COG0681	Belongs to the peptidase S26 family
FIV03_24630	COG0571	ribonuclease III activity
FIV03_24635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIV03_24640	COG1381	Involved in DNA repair and RecF pathway recombination
FIV03_24645	COG0681	Belongs to the peptidase S26 family
FIV03_24650	COG5001	Diguanylate cyclase
FIV03_24655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIV03_24660	COG2207	Transcriptional regulator
FIV03_24660	COG1917	Cupin 2, conserved barrel domain protein
FIV03_24670	COG1454	alcohol dehydrogenase
FIV03_24680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIV03_24685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV03_24690	COG0596	Alpha beta hydrolase
FIV03_24690	COG2945	thiolester hydrolase activity
FIV03_24705	COG4953	penicillin-binding protein 1C
FIV03_24710	COG2373	Large extracellular alpha-helical protein
FIV03_24715	COG1192	Involved in chromosome partitioning
FIV03_24725	COG2951	lytic endotransglycosylase activity
FIV03_24730	COG3639	organic phosphonate transmembrane transporter activity
FIV03_24740	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIV03_24745	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV03_24780	COG1522	sequence-specific DNA binding
FIV03_24795	COG0673	inositol 2-dehydrogenase activity
FIV03_24805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV03_24810	COG4989	oxidoreductase activity
FIV03_24815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIV03_24845	COG2855	membrane
FIV03_24850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV03_24850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV03_24855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV03_24870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV03_24875	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FIV03_24880	COG2267	carboxylic ester hydrolase activity
FIV03_24900	COG0589	response to stress
FIV03_24905	COG0583	DNA-binding transcription factor activity
FIV03_24910	COG0006	proline dipeptidase activity
FIV03_24925	COG0625	glutathione transferase activity
FIV03_24935	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIV03_24945	COG0673	inositol 2-dehydrogenase activity
FIV03_24950	COG0395	ABC-type sugar transport system, permease component
FIV03_24975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV03_24980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_24995	COG0395	ABC-type sugar transport system, permease component
FIV03_25035	COG1129	ABC transporter
FIV03_25045	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_25065	COG1024	Enoyl-CoA hydratase
FIV03_25075	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_25085	COG1609	Transcriptional regulator
FIV03_25090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_25095	COG1869	D-ribose catabolic process
FIV03_25100	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_25105	COG1129	ABC transporter
FIV03_25110	COG1879	ABC-type sugar transport system periplasmic component
FIV03_25155	COG2197	response regulator
FIV03_25160	COG1177	transmembrane transport
FIV03_25170	COG3842	ATPase activity
FIV03_25180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV03_25190	COG4221	oxidoreductase activity
FIV03_25195	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_25205	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_25210	COG1129	ABC transporter
FIV03_25215	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_25220	COG2721	sulfolactate sulfo-lyase activity
FIV03_25225	COG1802	Transcriptional regulator
FIV03_25265	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_25275	COG1137	ATPase activity
FIV03_25310	COG1846	Transcriptional regulator
FIV03_25320	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIV03_25330	COG0747	negative chemotaxis
FIV03_25335	COG0601	transmembrane transport
FIV03_25340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_25345	COG0444	Belongs to the ABC transporter superfamily
FIV03_25380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIV03_25455	COG0765	amino acid transport
FIV03_25460	COG0765	amino acid transport
FIV03_25465	COG1309	transcriptional regulator
FIV03_25470	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_25475	COG2814	Major facilitator Superfamily
FIV03_25495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV03_25520	COG3811	Belongs to the UPF0386 family
FIV03_25525	COG0789	Transcriptional regulator
FIV03_25565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV03_25565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV03_25570	COG1132	(ABC) transporter
FIV03_25580	COG0438	transferase activity, transferring glycosyl groups
FIV03_25585	COG0438	transferase activity, transferring glycosyl groups
FIV03_25590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIV03_25605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV03_25610	COG0456	acetyltransferase
FIV03_25620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV03_25625	COG0346	lactoylglutathione lyase activity
FIV03_25650	COG0583	DNA-binding transcription factor activity
FIV03_25660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV03_25665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_25670	COG0601	transmembrane transport
FIV03_25680	COG4172	Belongs to the ABC transporter superfamily
FIV03_25690	COG0494	nUDIX hydrolase
FIV03_25695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV03_25705	COG0308	aminopeptidase N
FIV03_25710	COG2202	Pas domain
FIV03_25710	COG2205	protein histidine kinase activity
FIV03_25720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIV03_25725	COG5002	protein histidine kinase activity
FIV03_25735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV03_25755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIV03_25770	COG3088	subunit of a heme lyase
FIV03_25775	COG1138	Cytochrome C-type biogenesis protein
FIV03_25780	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIV03_25785	COG4235	cytochrome complex assembly
FIV03_25800	COG2205	protein histidine kinase activity
FIV03_25805	COG0745	RESPONSE REGULATOR receiver
FIV03_25815	COG0438	transferase activity, transferring glycosyl groups
FIV03_25820	COG0561	phosphatase activity
FIV03_25840	COG1609	Transcriptional regulator
FIV03_25855	COG1073	alpha beta
FIV03_25875	COG2200	EAL domain
FIV03_25890	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_25900	COG0432	Pfam Uncharacterised protein family UPF0047
FIV03_25905	COG1819	glycosyl
FIV03_25920	COG0069	glutamate synthase activity
FIV03_25930	COG1132	(ABC) transporter
FIV03_25940	COG3300	MHYT domain
FIV03_25940	COG5001	Diguanylate cyclase
FIV03_25950	COG0251	oxidation-reduction process
FIV03_25980	COG0640	Transcriptional regulator
FIV03_25985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV03_26005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIV03_26005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_26020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIV03_26025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_26035	COG0175	sulfate reduction
FIV03_26090	COG3210	domain, Protein
FIV03_26115	COG1609	Transcriptional regulator
FIV03_26125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_26140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV03_26150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV03_26155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV03_26160	COG1121	(ABC) transporter
FIV03_26175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV03_26205	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIV03_26255	COG0583	DNA-binding transcription factor activity
FIV03_26275	COG0318	PFAM AMP-dependent synthetase and ligase
FIV03_26280	COG1272	protein, Hemolysin III
FIV03_26285	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_26285	COG1388	LysM domain
FIV03_26295	COG2188	Transcriptional regulator
FIV03_26300	COG4172	Belongs to the ABC transporter superfamily
FIV03_26305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_26310	COG0601	transmembrane transport
FIV03_26315	COG4166	transmembrane transport
FIV03_26340	COG1396	sequence-specific DNA binding
FIV03_26345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIV03_26380	COG1187	pseudouridine synthase activity
FIV03_26385	COG2813	Specifically methylates the guanine in position
FIV03_26405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV03_26410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIV03_26460	COG1131	(ABC) transporter
FIV03_26465	COG0842	Transport permease protein
FIV03_26470	COG0697	spore germination
FIV03_26480	COG3639	organic phosphonate transmembrane transporter activity
FIV03_26500	COG0784	Response regulator, receiver
FIV03_26500	COG4191	Histidine kinase
FIV03_26510	COG0850	regulation of cytokinetic process
FIV03_26520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FIV03_26530	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIV03_26545	COG1609	Transcriptional regulator
FIV03_26550	COG1129	ABC transporter
FIV03_26555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_26560	COG1879	ABC-type sugar transport system periplasmic component
FIV03_26570	COG0673	inositol 2-dehydrogenase activity
FIV03_26575	COG1879	ABC-type sugar transport system periplasmic component
FIV03_26580	COG1129	ABC transporter
FIV03_26585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_26590	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_26595	COG2186	Transcriptional regulator
FIV03_26620	COG4214	carbohydrate transport
FIV03_26630	COG4213	ABC transporter substrate-binding protein
FIV03_26645	COG0737	Belongs to the 5'-nucleotidase family
FIV03_26650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIV03_26655	COG0424	maF-like protein
FIV03_26660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIV03_26665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV03_26675	COG5328	Belongs to the UPF0262 family
FIV03_26700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIV03_26725	COG0384	phenazine biosynthesis protein PhzF
FIV03_26730	COG0583	DNA-binding transcription factor activity
FIV03_26740	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV03_26745	COG0745	RESPONSE REGULATOR receiver
FIV03_26745	COG3706	GGDEF domain
FIV03_26770	COG0411	ABC transporter
FIV03_26775	COG0410	ABC transporter
FIV03_26830	COG0443	Heat shock 70 kDa protein
FIV03_26845	COG2208	phosphoserine phosphatase activity
FIV03_26895	COG2875	Belongs to the precorrin methyltransferase family
FIV03_26900	COG2226	methyltransferase
FIV03_26905	COG1797	cobyrinic acid a,c-diamide synthase activity
FIV03_26915	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FIV03_26935	COG0438	transferase activity, transferring glycosyl groups
FIV03_26960	COG1442	glycosyl transferase family 8
FIV03_26960	COG1216	Glycosyl transferase, family 2
FIV03_26985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIV03_26995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV03_27010	COG0438	transferase activity, transferring glycosyl groups
FIV03_27025	COG2943	transferase activity, transferring hexosyl groups
FIV03_27030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV03_27035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIV03_27040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FIV03_27045	COG1137	ATPase activity
FIV03_27060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV03_27065	COG2010	Cytochrome c
FIV03_27085	COG0411	ABC transporter
FIV03_27095	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIV03_27110	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_27130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_27150	COG1968	undecaprenyl-diphosphatase activity
FIV03_27160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIV03_27170	COG3383	formate dehydrogenase (NAD+) activity
FIV03_27180	COG0494	nUDIX hydrolase
FIV03_27190	COG0793	Belongs to the peptidase S41A family
FIV03_27205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIV03_27210	COG0799	negative regulation of ribosome biogenesis
FIV03_27215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIV03_27220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIV03_27230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIV03_27250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIV03_27255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIV03_27255	COG3743	rRNA binding
FIV03_27270	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_27295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV03_27305	COG0583	DNA-binding transcription factor activity
FIV03_27345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV03_27360	COG0022	dehydrogenase e1 component
FIV03_27365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIV03_27370	COG0006	proline dipeptidase activity
FIV03_27380	COG1653	transport
FIV03_27385	COG1879	ABC-type sugar transport system periplasmic component
FIV03_27390	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_27395	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_27400	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_27405	COG1129	ABC transporter
FIV03_27425	COG2186	Transcriptional regulator
FIV03_27430	COG0745	RESPONSE REGULATOR receiver
FIV03_27430	COG3706	GGDEF domain
FIV03_27435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV03_27435	COG0784	Response regulator, receiver
FIV03_27435	COG2205	protein histidine kinase activity
FIV03_27435	COG2198	Histidine kinase
FIV03_27455	COG0411	ABC transporter
FIV03_27460	COG0410	ABC transporter
FIV03_27465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV03_27470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIV03_27480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIV03_27490	COG0745	RESPONSE REGULATOR receiver
FIV03_27500	COG0500	methyltransferase
FIV03_27510	COG2217	Heavy metal translocating P-type atpase
FIV03_27525	COG2010	Cytochrome c
FIV03_27540	COG3278	Belongs to the heme-copper respiratory oxidase family
FIV03_27545	COG0697	spore germination
FIV03_27575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIV03_27590	COG4566	intracellular signal transduction
FIV03_27595	COG4191	Histidine kinase
FIV03_27600	COG0436	Aminotransferase
FIV03_27605	COG0784	Response regulator, receiver
FIV03_27605	COG2205	protein histidine kinase activity
FIV03_27605	COG2198	Histidine kinase
FIV03_27610	COG5001	Diguanylate cyclase
FIV03_27630	COG1793	dna ligase
FIV03_27650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIV03_27650	COG1793	dna ligase
FIV03_27660	COG1201	RNA secondary structure unwinding
FIV03_27680	COG0628	permease
FIV03_27690	COG0730	response to heat
FIV03_27700	COG0789	Transcriptional regulator
FIV03_27705	COG1960	acyl-CoA dehydrogenase activity
FIV03_27715	COG0183	Belongs to the thiolase family
FIV03_27725	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV03_27725	COG1024	Enoyl-CoA hydratase
FIV03_27745	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIV03_27750	COG0534	Mate efflux family protein
FIV03_27755	COG0167	dihydroorotate dehydrogenase activity
FIV03_27780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIV03_27785	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FIV03_27805	COG2967	ApaG domain
FIV03_27810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIV03_27820	COG0717	Belongs to the dCTP deaminase family
FIV03_27825	COG1739	Uncharacterized protein family UPF0029
FIV03_27865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FIV03_27870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIV03_27875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV03_27890	COG0745	RESPONSE REGULATOR receiver
FIV03_27895	COG0704	Plays a role in the regulation of phosphate uptake
FIV03_27900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV03_27910	COG0573	inorganic phosphate transmembrane transporter activity
FIV03_27925	COG5002	protein histidine kinase activity
FIV03_27940	COG1660	Displays ATPase and GTPase activities
FIV03_27955	COG0598	Magnesium transport protein CorA
FIV03_27970	COG0484	heat shock protein binding
FIV03_28005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV03_28020	COG0583	DNA-binding transcription factor activity
FIV03_28035	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_28040	COG3300	MHYT domain
FIV03_28040	COG5001	Diguanylate cyclase
FIV03_28045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIV03_28065	COG0668	transmembrane transport
FIV03_28075	COG1733	regulation of RNA biosynthetic process
FIV03_28085	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_28090	COG1024	Enoyl-CoA hydratase
FIV03_28095	COG1960	acyl-CoA dehydrogenase activity
FIV03_28100	COG0009	L-threonylcarbamoyladenylate synthase
FIV03_28105	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIV03_28110	COG1722	exodeoxyribonuclease VII activity
FIV03_28120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIV03_28140	COG1999	signal sequence binding
FIV03_28160	COG2226	methyltransferase
FIV03_28165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV03_28165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV03_28180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIV03_28205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV03_28225	COG1129	ABC transporter
FIV03_28230	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_28245	COG2186	Transcriptional regulator
FIV03_28285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV03_28290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_28300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_28310	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_28325	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_28330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV03_28340	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_28345	COG0402	S-adenosylhomocysteine deaminase activity
FIV03_28350	COG0747	negative chemotaxis
FIV03_28355	COG4608	Belongs to the ABC transporter superfamily
FIV03_28360	COG0444	Belongs to the ABC transporter superfamily
FIV03_28365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV03_28375	COG0747	negative chemotaxis
FIV03_28385	COG2186	Transcriptional regulator
FIV03_28410	COG4608	Belongs to the ABC transporter superfamily
FIV03_28425	COG0601	transmembrane transport
FIV03_28430	COG0747	negative chemotaxis
FIV03_28435	COG1396	sequence-specific DNA binding
FIV03_28465	COG2175	clavaminate synthase activity
FIV03_28470	COG0583	DNA-binding transcription factor activity
FIV03_28480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV03_28490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV03_28530	COG0129	dihydroxy-acid dehydratase activity
FIV03_28535	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_28550	COG1414	Transcriptional regulator
FIV03_28565	COG0395	ABC-type sugar transport system, permease component
FIV03_28575	COG3547	Transposase (IS116 IS110 IS902 family)
FIV03_28595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV03_28635	COG1070	Carbohydrate kinase
FIV03_28640	COG1349	DNA-binding transcription factor activity
FIV03_28650	COG3842	ATPase activity
FIV03_28665	COG1175	transmembrane transport
FIV03_28670	COG0434	BtpA family
FIV03_28675	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV03_28680	COG3831	ATPase activity
FIV03_28690	COG4974	Belongs to the 'phage' integrase family
FIV03_28695	COG0477	Major facilitator Superfamily
FIV03_28710	COG1629	transport
FIV03_28710	COG4774	siderophore transport
FIV03_28715	COG2867	negative regulation of translational initiation
FIV03_28715	COG2226	methyltransferase
FIV03_28720	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_28725	COG1535	isochorismatase
FIV03_28725	COG3433	isochorismatase activity
FIV03_28730	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIV03_28740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV03_28745	COG3433	isochorismatase activity
FIV03_28745	COG2226	methyltransferase
FIV03_28745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV03_28750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV03_28750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FIV03_28755	COG1609	Transcriptional regulator
FIV03_28760	COG0673	inositol 2-dehydrogenase activity
FIV03_28770	COG1653	transport
FIV03_28775	COG1175	transmembrane transport
FIV03_28780	COG3833	ABC-type maltose transport systems, permease component
FIV03_28785	COG3842	ATPase activity
FIV03_28790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIV03_28795	COG2076	Multidrug Resistance protein
FIV03_28805	COG0590	tRNA wobble adenosine to inosine editing
FIV03_28815	COG0583	DNA-binding transcription factor activity
FIV03_28820	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIV03_28830	COG1280	lysine exporter protein (LysE YggA)
FIV03_28835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV03_28840	COG1595	DNA-templated transcription, initiation
FIV03_28880	COG0384	phenazine biosynthesis protein PhzF
FIV03_28885	COG0583	DNA-binding transcription factor activity
FIV03_28900	COG4585	Histidine kinase
FIV03_28905	COG1879	ABC-type sugar transport system periplasmic component
FIV03_28910	COG1129	ABC transporter
FIV03_28925	COG3386	PFAM SMP-30 Gluconolaconase
FIV03_28930	COG1063	alcohol dehydrogenase
FIV03_28945	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_28960	COG0246	Mannitol dehydrogenase
FIV03_28965	COG1940	carbohydrate kinase activity
FIV03_28975	COG1879	ABC-type sugar transport system periplasmic component
FIV03_28980	COG1129	ABC transporter
FIV03_28985	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_29000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV03_29015	COG0183	Belongs to the thiolase family
FIV03_29045	COG0156	8-amino-7-oxononanoate synthase activity
FIV03_29065	COG1845	cytochrome c oxidase, subunit III
FIV03_29075	COG0714	Associated with various cellular activities
FIV03_29090	COG2010	Cytochrome c
FIV03_29095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV03_29100	COG2010	Cytochrome c
FIV03_29105	COG3391	amine dehydrogenase activity
FIV03_29215	COG0477	Major facilitator Superfamily
FIV03_29280	COG4604	ABC transporter, ATP-binding protein
FIV03_29285	COG4605	iron ion homeostasis
FIV03_29290	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_29300	COG1309	transcriptional regulator
FIV03_29310	COG1122	ATPase activity
FIV03_29325	COG0601	transmembrane transport
FIV03_29350	COG1780	Probably involved in ribonucleotide reductase function
FIV03_29360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV03_29380	COG0601	transmembrane transport
FIV03_29405	COG0640	Transcriptional regulator
FIV03_29440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIV03_29445	COG0163	prenyltransferase activity
FIV03_29460	COG2376	Dihydroxyacetone kinase
FIV03_29465	COG1461	Dihydroxyacetone kinase
FIV03_29470	COG2376	Dihydroxyacetone kinase
FIV03_29485	COG1129	ABC transporter
FIV03_29490	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_29500	COG2390	Transcriptional regulator
FIV03_29505	COG1349	DNA-binding transcription factor activity
FIV03_29510	COG1879	ABC-type sugar transport system periplasmic component
FIV03_29515	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_29520	COG1129	ABC transporter
FIV03_29555	COG1349	DNA-binding transcription factor activity
FIV03_29580	COG0583	DNA-binding transcription factor activity
FIV03_29590	COG1280	lysine exporter protein (LysE YggA)
FIV03_29600	COG0395	ABC-type sugar transport system, permease component
FIV03_29605	COG1175	transmembrane transport
FIV03_29620	COG3534	alpha-L-arabinofuranosidase
FIV03_29630	COG0583	DNA-binding transcription factor activity
FIV03_29635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV03_29645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV03_29650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV03_29655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV03_29660	COG1024	Enoyl-CoA hydratase
FIV03_29665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIV03_29670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV03_29675	COG1012	belongs to the aldehyde dehydrogenase family
FIV03_29685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV03_29695	COG0625	glutathione transferase activity
FIV03_29700	COG5507	3-demethylubiquinone-9 3-methyltransferase
FIV03_29705	COG1733	regulation of RNA biosynthetic process
FIV03_29710	COG1737	Transcriptional regulator
FIV03_29720	COG1175	transmembrane transport
FIV03_29725	COG0395	ABC-type sugar transport system, permease component
FIV03_29760	COG4941	Belongs to the sigma-70 factor family
FIV03_29765	COG3795	YCII-related domain
FIV03_29780	COG2197	response regulator
FIV03_29785	COG3239	Fatty acid desaturase
FIV03_29790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV03_29800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_29805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV03_29825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV03_29835	COG3707	response regulator
FIV03_29855	COG1137	ATPase activity
FIV03_29865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV03_29880	COG1192	Involved in chromosome partitioning
FIV03_29885	COG1475	DNA binding
FIV03_29890	COG1414	Transcriptional regulator
FIV03_29895	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FIV03_29915	COG3279	Response regulator of the LytR AlgR family
FIV03_29920	COG3275	phosphorelay sensor kinase activity
FIV03_29940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIV03_29985	COG2010	Cytochrome c
FIV03_30010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_30015	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV03_30025	COG3386	PFAM SMP-30 Gluconolaconase
FIV03_30030	COG3842	ATPase activity
FIV03_30045	COG1175	transmembrane transport
FIV03_30050	COG3833	ABC-type maltose transport systems, permease component
FIV03_30060	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_30070	COG3734	2-keto-3-deoxy-galactonokinase
FIV03_30080	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_30085	COG3842	ATPase activity
FIV03_30090	COG0395	ABC-type sugar transport system, permease component
FIV03_30095	COG1175	transmembrane transport
FIV03_30105	COG1609	Transcriptional regulator
FIV03_30110	COG0740	serine-type endopeptidase activity
FIV03_30145	COG2186	Transcriptional regulator
FIV03_30175	COG1595	DNA-templated transcription, initiation
FIV03_30180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV03_30190	COG4948	Mandelate Racemase Muconate Lactonizing
FIV03_30195	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_30210	COG3254	rhamnose metabolic process
FIV03_30220	COG3842	ATPase activity
FIV03_30225	COG0395	ABC-type sugar transport system, permease component
FIV03_30230	COG1175	transmembrane transport
FIV03_30245	COG3618	amidohydrolase
FIV03_30265	COG1846	Transcriptional regulator
FIV03_30300	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIV03_30315	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV03_30340	COG0745	RESPONSE REGULATOR receiver
FIV03_30345	COG0642	Histidine kinase
FIV03_30360	COG0583	DNA-binding transcription factor activity
FIV03_30365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV03_30380	COG1846	Transcriptional regulator
FIV03_30385	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_30395	COG0583	DNA-binding transcription factor activity
FIV03_30400	COG0740	serine-type endopeptidase activity
FIV03_30405	COG0473	3-isopropylmalate dehydrogenase activity
FIV03_30405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV03_30455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV03_30460	COG1028	Short-chain dehydrogenase reductase Sdr
FIV03_30465	COG0371	Dehydrogenase
FIV03_30475	COG1175	transmembrane transport
FIV03_30490	COG1070	Carbohydrate kinase
FIV03_30495	COG0277	FAD linked oxidase domain protein
FIV03_30500	COG1609	Transcriptional regulator
FIV03_30520	COG2204	response regulator
FIV03_30525	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV03_30545	COG0438	transferase activity, transferring glycosyl groups
FIV03_30585	COG0438	transferase activity, transferring glycosyl groups
FIV03_30590	COG0463	Glycosyl transferase, family 2
FIV03_30595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV03_30640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV03_30645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIV03_30670	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FIV03_30695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIV03_30705	COG1476	TRANSCRIPTIONal
FIV03_30715	COG1850	ribulose-bisphosphate carboxylase activity
FIV03_30720	COG0287	Prephenate dehydrogenase
FIV03_30725	COG1879	ABC-type sugar transport system periplasmic component
FIV03_30740	COG3701	Conjugal transfer protein
FIV03_30745	COG3846	protein secretion by the type IV secretion system
FIV03_30755	COG5314	conjugation
FIV03_30760	COG3451	type IV secretory pathway VirB4
FIV03_30765	COG5268	conjugation
FIV03_30770	COG3838	Conjugal transfer protein Trbc
FIV03_30775	COG4962	Type ii secretion system protein e
FIV03_30800	COG3436	PFAM IS66 Orf2 family protein
FIV03_30825	COG2207	Transcriptional regulator
FIV03_30830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV03_30835	COG1454	alcohol dehydrogenase
FIV03_30840	COG1960	acyl-CoA dehydrogenase activity
FIV03_30885	COG0183	Belongs to the thiolase family
FIV03_30910	COG1129	ABC transporter
FIV03_30915	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV03_30920	COG1737	Transcriptional regulator
FIV03_30925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV03_30935	COG2801	Transposase and inactivated derivatives
FIV03_30950	COG1078	dGTPase activity
FIV03_30960	COG2176	DNA-directed DNA polymerase activity
FIV03_30985	COG1476	TRANSCRIPTIONal
FIV03_30990	COG1525	nuclease
FIV03_31010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV03_31045	COG2184	nucleotidyltransferase activity
FIV03_31065	COG1414	Transcriptional regulator
FIV03_31070	COG1475	DNA binding
FIV03_31075	COG1192	Involved in chromosome partitioning
FIV03_31100	COG3547	Transposase (IS116 IS110 IS902 family)
FIV03_31105	COG4957	zinc ion binding
FIV03_31135	COG4962	Type ii secretion system protein e
FIV03_31140	COG3838	Conjugal transfer protein Trbc
FIV03_31145	COG5268	conjugation
FIV03_31165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIV03_31170	COG0739	heme binding
FIV03_31175	COG0671	phosphoesterase, PA-phosphatase related
FIV03_31185	COG4372	Transposase
FIV03_31190	COG3436	PFAM IS66 Orf2 family protein
FIV03_31195	COG2963	transposase activity
FIV03_31200	COG3547	Transposase (IS116 IS110 IS902 family)
FIV03_31210	COG1321	iron dependent repressor
FIV03_31225	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV03_31230	COG3639	organic phosphonate transmembrane transporter activity
FIV03_31245	COG3034	peptidoglycan biosynthetic process
FIV03_31260	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_31265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIV03_31270	COG4644	lycopene metabolic process
FIV03_31315	COG2135	peptidase activity
FIV03_31325	COG0840	transmembrane signaling receptor activity
FIV03_31345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV03_31370	COG5489	Protein of unknown function (DUF736)
FIV03_31415	COG1475	DNA binding
FIV03_31490	COG1196	nuclear chromosome segregation
FIV03_31510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIV03_31515	COG1414	Transcriptional regulator
FIV03_31520	COG1475	DNA binding
FIV03_31525	COG1192	Involved in chromosome partitioning
FIV03_31535	COG4957	zinc ion binding
FIV03_31545	COG4962	Type ii secretion system protein e
FIV03_31550	COG3838	Conjugal transfer protein Trbc
FIV03_31555	COG5268	conjugation
FIV03_31560	COG3451	type IV secretory pathway VirB4
FIV03_31565	COG5314	conjugation
FIV03_31575	COG3846	protein secretion by the type IV secretion system
FIV03_31580	COG3701	Conjugal transfer protein
FIV03_31625	COG0659	secondary active sulfate transmembrane transporter activity
FIV03_31655	COG0739	heme binding
FIV03_31665	COG1321	iron dependent repressor
FIV03_31680	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV03_31685	COG3639	organic phosphonate transmembrane transporter activity
FIV03_31700	COG3034	peptidoglycan biosynthetic process
FIV03_31715	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_31720	COG1388	LysM domain
FIV03_31720	COG1376	ErfK ybiS ycfS ynhG family protein
FIV03_31740	COG1230	cation diffusion facilitator family transporter
FIV03_31750	COG0789	Transcriptional regulator
FIV03_31765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIV03_31775	COG1999	signal sequence binding
FIV03_31785	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIV03_31790	COG2433	Pfam Transposase IS66
FIV03_31855	COG0583	DNA-binding transcription factor activity
FIV03_31880	COG1192	Involved in chromosome partitioning
FIV03_31925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV03_31935	COG4778	phosphonate C-P lyase system protein PhnL
FIV03_31940	COG4107	phosphonate C-P lyase system protein PhnK
FIV03_31945	COG3627	carbon phosphorus lyase activity
FIV03_31950	COG3626	phosphonate metabolism