locus-tag	class	description
H9Q78_00005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q78_00015	COG1595	DNA-templated transcription, initiation
H9Q78_00025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9Q78_00030	COG0459	protein refolding
H9Q78_00035	COG0517	IMP dehydrogenase activity
H9Q78_00035	COG0516	GMP reductase activity
H9Q78_00060	COG0628	permease
H9Q78_00100	COG0493	'glutamate synthase
H9Q78_00100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q78_00115	COG0697	spore germination
H9Q78_00135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9Q78_00140	COG0210	DNA helicase
H9Q78_00155	COG4684	Psort location CytoplasmicMembrane, score
H9Q78_00160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9Q78_00165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9Q78_00170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q78_00175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H9Q78_00190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H9Q78_00220	COG1979	alcohol dehydrogenase
H9Q78_00230	COG1979	alcohol dehydrogenase
H9Q78_00235	COG2873	o-acetylhomoserine
H9Q78_00250	COG0549	Belongs to the carbamate kinase family
H9Q78_00255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9Q78_00275	COG1132	(ABC) transporter
H9Q78_00285	COG0191	fructose-bisphosphate aldolase activity
H9Q78_00290	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
H9Q78_00325	COG1797	cobyrinic acid a,c-diamide synthase activity
H9Q78_00330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H9Q78_00340	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H9Q78_00360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9Q78_00365	COG1492	cobalamin metabolic process
H9Q78_00400	COG0310	cobalt ion transport
H9Q78_00405	COG0406	alpha-ribazole phosphatase activity
H9Q78_00410	COG1686	Belongs to the peptidase S11 family
H9Q78_00420	COG0484	heat shock protein binding
H9Q78_00435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9Q78_00450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H9Q78_00470	COG2081	HI0933 family
H9Q78_00475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9Q78_00480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9Q78_00485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9Q78_00485	COG0539	negative regulation of cytoplasmic translation
H9Q78_00490	COG2235	arginine
H9Q78_00495	COG4166	transmembrane transport
H9Q78_00500	COG0601	transmembrane transport
H9Q78_00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q78_00510	COG0444	Belongs to the ABC transporter superfamily
H9Q78_00515	COG4608	Belongs to the ABC transporter superfamily
H9Q78_00545	COG0632	four-way junction helicase activity
H9Q78_00550	COG2255	four-way junction helicase activity
H9Q78_00560	COG0826	peptidase U32
H9Q78_00570	COG0768	penicillin binding
H9Q78_00580	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9Q78_00635	COG2207	Transcriptional regulator
H9Q78_00655	COG1160	GTP binding
H9Q78_00660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9Q78_00680	COG0534	Mate efflux family protein
H9Q78_00685	COG0534	Mate efflux family protein
H9Q78_00705	COG1263	PTS System
H9Q78_00705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q78_00720	COG0742	ribosomal rna small subunit methyltransferase
H9Q78_00725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9Q78_00745	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q78_00755	COG2357	RelA SpoT domain protein
H9Q78_00760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9Q78_00760	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H9Q78_00765	COG0546	phosphoglycolate phosphatase activity
H9Q78_00775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9Q78_00790	COG3331	DNA recombination
H9Q78_00795	COG0124	histidyl-tRNA synthetase
H9Q78_00800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9Q78_00805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9Q78_00810	COG0131	Imidazoleglycerol-phosphate dehydratase
H9Q78_00835	COG0601	transmembrane transport
H9Q78_00875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9Q78_00895	COG3843	relaxase mobilization nuclease domain protein
H9Q78_00915	COG0551	DNA topoisomerase type I activity
H9Q78_00915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q78_00930	COG0791	NLP P60 protein
H9Q78_00930	COG0741	lytic transglycosylase activity
H9Q78_01025	COG1530	ribonuclease E activity
H9Q78_01045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9Q78_01050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9Q78_01055	COG1534	Rna-binding protein
H9Q78_01060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9Q78_01065	COG1713	HD superfamily hydrolase involved in NAD metabolism
H9Q78_01070	COG0799	negative regulation of ribosome biogenesis
H9Q78_01095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9Q78_01105	COG4974	Belongs to the 'phage' integrase family
H9Q78_01110	COG0037	tRNA processing
H9Q78_01115	COG4989	oxidoreductase activity
H9Q78_01120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9Q78_01125	COG4608	Belongs to the ABC transporter superfamily
H9Q78_01130	COG0444	Belongs to the ABC transporter superfamily
H9Q78_01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q78_01145	COG0747	negative chemotaxis
H9Q78_01155	COG0564	pseudouridine synthase activity
H9Q78_01160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9Q78_01165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9Q78_01185	COG2155	Conserved Protein
H9Q78_01195	COG1686	Belongs to the peptidase S11 family
H9Q78_01200	COG1803	Methylglyoxal synthase
H9Q78_01205	COG0772	Belongs to the SEDS family
H9Q78_01210	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9Q78_01215	COG2894	cell division
H9Q78_01220	COG0850	regulation of cytokinetic process
H9Q78_01225	COG0768	penicillin binding
H9Q78_01240	COG2003	Belongs to the UPF0758 family
H9Q78_01245	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H9Q78_01250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9Q78_01260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9Q78_01270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q78_01275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9Q78_01280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9Q78_01285	COG4224	UPF0291 protein
H9Q78_01290	COG4667	esterase of the alpha-beta hydrolase superfamily
H9Q78_01295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9Q78_01300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H9Q78_01305	COG2081	HI0933 family
H9Q78_01325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9Q78_01330	COG1702	phosphate starvation-inducible protein PhoH
H9Q78_01345	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9Q78_01350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q78_01360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9Q78_01365	COG0328	RNA-DNA hybrid ribonuclease activity
H9Q78_01370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9Q78_01375	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9Q78_01390	COG3250	beta-galactosidase activity
H9Q78_01395	COG0673	inositol 2-dehydrogenase activity
H9Q78_01400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q78_01410	COG0813	purine-nucleoside phosphorylase activity
H9Q78_01415	COG1309	transcriptional regulator
H9Q78_01420	COG1522	sequence-specific DNA binding
H9Q78_01430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9Q78_01435	COG3404	Formiminotransferase-cyclodeaminase
H9Q78_01440	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9Q78_01450	COG0633	Ferredoxin
H9Q78_01480	COG1151	hydroxylamine reductase activity
H9Q78_01490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9Q78_01505	COG0653	protein targeting
H9Q78_01525	COG1131	(ABC) transporter
H9Q78_01535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9Q78_01540	COG1461	Dihydroxyacetone kinase
H9Q78_01550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9Q78_01575	COG1546	Belongs to the CinA family
H9Q78_01575	COG1058	Belongs to the CinA family
H9Q78_01585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q78_01590	COG1758	RNA polymerase activity
H9Q78_01595	COG0194	GDP metabolic process
H9Q78_01600	COG2052	Domain of unknown function (DUF370)
H9Q78_01605	COG1561	YicC-like family, N-terminal region
H9Q78_01610	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H9Q78_01615	COG0330	HflC and HflK could
H9Q78_01625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9Q78_01630	COG0552	protein localization to endoplasmic reticulum
H9Q78_01635	COG1196	nuclear chromosome segregation
H9Q78_01640	COG0571	ribonuclease III activity
H9Q78_01645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q78_01650	COG0416	fatty acid biosynthetic process
H9Q78_01660	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q78_01670	COG0280	phosphate acetyltransferase
H9Q78_01675	COG1323	Belongs to the UPF0348 family
H9Q78_01680	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_01685	COG2848	UPF0210 protein
H9Q78_01695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9Q78_01700	COG0237	dephospho-CoA kinase activity
H9Q78_01720	COG0789	Transcriptional regulator
H9Q78_01720	COG4978	Transcriptional regulator
H9Q78_01725	COG1720	tRNA m6t6A37 methyltransferase activity
H9Q78_01740	COG2378	regulation of single-species biofilm formation
H9Q78_01765	COG1966	Carbon starvation protein
H9Q78_01770	COG3022	response to hydroperoxide
H9Q78_01775	COG1496	oxidoreductase activity
H9Q78_01780	COG0792	nuclease activity
H9Q78_01785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q78_01805	COG0335	large ribosomal subunit rRNA binding
H9Q78_01810	COG0336	Belongs to the RNA methyltransferase TrmD family
H9Q78_01820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9Q78_01835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9Q78_01865	COG0352	thiamine-phosphate diphosphorylase activity
H9Q78_01880	COG2022	thiamine diphosphate biosynthetic process
H9Q78_01885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9Q78_01890	COG2104	thiamine diphosphate biosynthetic process
H9Q78_01890	COG2022	thiamine diphosphate biosynthetic process
H9Q78_01905	COG0297	glycogen (starch) synthase activity
H9Q78_01910	COG0745	RESPONSE REGULATOR receiver
H9Q78_01915	COG0750	zinc metalloprotease
H9Q78_01920	COG0497	DNA recombination
H9Q78_01925	COG1438	arginine binding
H9Q78_01930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9Q78_01935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9Q78_01940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q78_01950	COG1722	exodeoxyribonuclease VII activity
H9Q78_01955	COG1570	exodeoxyribonuclease VII activity
H9Q78_01960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q78_01965	COG1302	Protein conserved in bacteria
H9Q78_02005	COG3854	ATPases associated with a variety of cellular activities
H9Q78_02020	COG0346	lactoylglutathione lyase activity
H9Q78_02050	COG0275	rRNA processing
H9Q78_02060	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9Q78_02095	COG1309	transcriptional regulator
H9Q78_02110	COG1595	DNA-templated transcription, initiation
H9Q78_02115	COG3706	GGDEF domain
H9Q78_02125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9Q78_02135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q78_02155	COG0010	Belongs to the arginase family
H9Q78_02185	COG1126	abc transporter atp-binding protein
H9Q78_02190	COG0765	amino acid transport
H9Q78_02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q78_02205	COG1115	amino acid carrier protein
H9Q78_02210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9Q78_02215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9Q78_02220	COG4948	Mandelate Racemase Muconate Lactonizing
H9Q78_02235	COG2309	aminopeptidase activity
H9Q78_02250	COG1914	H( )-stimulated, divalent metal cation uptake system
H9Q78_02260	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q78_02280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9Q78_02285	COG0045	succinate-CoA ligase (ADP-forming) activity
H9Q78_02295	COG1013	pyruvate-flavodoxin oxidoreductase activity
H9Q78_02300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q78_02320	COG0495	leucyl-tRNA aminoacylation
H9Q78_02325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9Q78_02335	COG1253	flavin adenine dinucleotide binding
H9Q78_02340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q78_02350	COG0215	cysteine-tRNA ligase activity
H9Q78_02355	COG1045	serine acetyltransferase
H9Q78_02360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9Q78_02365	COG1125	glycine betaine transport
H9Q78_02365	COG0517	IMP dehydrogenase activity
H9Q78_02370	COG1174	glycine betaine transport
H9Q78_02425	COG1597	lipid kinase activity
H9Q78_02435	COG1266	CAAX protease self-immunity
H9Q78_02440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9Q78_02450	COG3409	Peptidoglycan-binding domain 1 protein
H9Q78_02495	COG5002	protein histidine kinase activity
H9Q78_02500	COG0745	RESPONSE REGULATOR receiver
H9Q78_02505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9Q78_02510	COG0704	Plays a role in the regulation of phosphate uptake
H9Q78_02515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q78_02520	COG0581	inorganic phosphate transmembrane transporter activity
H9Q78_02525	COG0573	inorganic phosphate transmembrane transporter activity
H9Q78_02530	COG1686	Belongs to the peptidase S11 family
H9Q78_02535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9Q78_02540	COG1368	sulfuric ester hydrolase activity
H9Q78_02550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9Q78_02560	COG0494	nUDIX hydrolase
H9Q78_02565	COG1418	mRNA catabolic process
H9Q78_02570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9Q78_02685	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9Q78_02685	COG3103	Sh3 type 3 domain protein
H9Q78_02685	COG4991	sh3 domain protein
H9Q78_02705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9Q78_02710	COG0557	exoribonuclease II activity
H9Q78_02715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9Q78_02720	COG0148	phosphopyruvate hydratase activity
H9Q78_02730	COG0072	phenylalanine-tRNA ligase activity
H9Q78_02730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q78_02735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9Q78_02740	COG1295	ribonuclease BN
H9Q78_02745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9Q78_02750	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H9Q78_02755	COG0628	permease
H9Q78_02760	COG0719	Fe-S assembly protein
H9Q78_02765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9Q78_02775	COG1380	Effector of murein hydrolase LrgA
H9Q78_02800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H9Q78_02815	COG3620	sequence-specific DNA binding
H9Q78_02830	COG1122	ATPase activity
H9Q78_02840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q78_02865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9Q78_02875	COG1126	abc transporter atp-binding protein
H9Q78_02880	COG0765	amino acid transport
H9Q78_02885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q78_02900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q78_02935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9Q78_02955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9Q78_02980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q78_02990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q78_03000	COG1959	2 iron, 2 sulfur cluster binding
H9Q78_03005	COG0534	Mate efflux family protein
H9Q78_03015	COG0052	Belongs to the universal ribosomal protein uS2 family
H9Q78_03030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q78_03035	COG0758	DNA mediated transformation
H9Q78_03040	COG0606	chelatase, subunit chli
H9Q78_03055	COG0549	Belongs to the carbamate kinase family
H9Q78_03065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q78_03070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q78_03090	COG5002	protein histidine kinase activity
H9Q78_03095	COG0745	RESPONSE REGULATOR receiver
H9Q78_03115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9Q78_03120	COG0419	ATPase involved in DNA repair
H9Q78_03130	COG0561	phosphatase activity
H9Q78_03145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q78_03160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9Q78_03170	COG0515	serine threonine protein kinase
H9Q78_03170	COG2815	serine threonine protein kinase
H9Q78_03175	COG0631	protein serine/threonine phosphatase activity
H9Q78_03180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9Q78_03190	COG2738	Putative neutral zinc metallopeptidase
H9Q78_03205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9Q78_03210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9Q78_03225	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9Q78_03245	COG2720	vancomycin resistance protein
H9Q78_03250	COG0540	Belongs to the ATCase OTCase family
H9Q78_03275	COG0671	phosphoesterase, PA-phosphatase related
H9Q78_03285	COG0583	DNA-binding transcription factor activity
H9Q78_03300	COG0534	Mate efflux family protein
H9Q78_03305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9Q78_03310	COG1115	amino acid carrier protein
H9Q78_03315	COG0577	efflux transmembrane transporter activity
H9Q78_03320	COG1136	(ABC) transporter
H9Q78_03325	COG5002	protein histidine kinase activity
H9Q78_03330	COG0745	RESPONSE REGULATOR receiver
H9Q78_03340	COG0138	bifunctional purine biosynthesis protein purh
H9Q78_03355	COG1408	metallophosphoesterase
H9Q78_03365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9Q78_03365	COG0512	Glutamine amidotransferase of anthranilate synthase
H9Q78_03370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9Q78_03370	COG0512	Glutamine amidotransferase of anthranilate synthase
H9Q78_03380	COG1126	abc transporter atp-binding protein
H9Q78_03385	COG0765	amino acid transport
H9Q78_03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q78_03395	COG0423	glycine-tRNA ligase activity
H9Q78_03405	COG1381	Involved in DNA repair and RecF pathway recombination
H9Q78_03425	COG0826	peptidase U32
H9Q78_03430	COG4122	O-methyltransferase activity
H9Q78_03440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9Q78_03455	COG4472	Bacterial protein of unknown function (DUF965)
H9Q78_03460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q78_03475	COG1104	cysteine desulfurase activity
H9Q78_03480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9Q78_03485	COG2264	protein methyltransferase activity
H9Q78_03560	COG2135	peptidase activity
H9Q78_03565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q78_03575	COG0740	serine-type endopeptidase activity
H9Q78_03580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q78_03595	COG0534	Mate efflux family protein
H9Q78_03605	COG1368	sulfuric ester hydrolase activity
H9Q78_03610	COG1968	undecaprenyl-diphosphatase activity
H9Q78_03620	COG0107	imidazoleglycerol-phosphate synthase activity
H9Q78_03625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9Q78_03655	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9Q78_03670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9Q78_03685	COG1621	beta-fructofuranosidase activity
H9Q78_03690	COG1263	PTS System
H9Q78_03690	COG2190	(PTS) system
H9Q78_03690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q78_03695	COG1609	Transcriptional regulator
H9Q78_03710	COG1132	(ABC) transporter
H9Q78_03745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9Q78_03745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9Q78_03750	COG2217	Heavy metal translocating P-type atpase
H9Q78_03760	COG1309	transcriptional regulator
H9Q78_03780	COG0640	Transcriptional regulator
H9Q78_03845	COG1116	anion transmembrane transporter activity
H9Q78_03850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9Q78_03865	COG1362	aminopeptidase activity
H9Q78_03875	COG0326	Molecular chaperone. Has ATPase activity
H9Q78_03910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9Q78_03915	COG0066	3-isopropylmalate dehydratase activity
H9Q78_03920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9Q78_03925	COG0583	DNA-binding transcription factor activity
H9Q78_03935	COG2239	Acts as a magnesium transporter
H9Q78_03950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9Q78_03955	COG0440	acetolactate synthase activity
H9Q78_03965	COG2205	protein histidine kinase activity
H9Q78_03965	COG2198	Histidine kinase
H9Q78_03965	COG0784	Response regulator, receiver
H9Q78_03975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9Q78_03980	COG0475	glutathione-regulated potassium exporter activity
H9Q78_03985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9Q78_03995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9Q78_04000	COG1592	Rubrerythrin
H9Q78_04005	COG1573	uracil-dna glycosylase
H9Q78_04055	COG0596	Alpha beta hydrolase
H9Q78_04060	COG2205	protein histidine kinase activity
H9Q78_04060	COG0784	Response regulator, receiver
H9Q78_04065	COG1278	Cold shock
H9Q78_04075	COG0516	GMP reductase activity
H9Q78_04075	COG0517	IMP dehydrogenase activity
H9Q78_04110	COG2315	Protein conserved in bacteria
H9Q78_04135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q78_04140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9Q78_04180	COG5001	Diguanylate cyclase
H9Q78_04180	COG3300	MHYT domain
H9Q78_04200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q78_04225	COG4260	virion core protein, lumpy skin disease virus
H9Q78_04230	COG1842	Phage shock protein A
H9Q78_04240	COG4496	protein, YerC YecD
H9Q78_04245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q78_04250	COG0561	phosphatase activity
H9Q78_04275	COG0251	oxidation-reduction process
H9Q78_04280	COG2996	Protein conserved in bacteria
H9Q78_04290	COG0561	phosphatase activity
H9Q78_04310	COG1794	racemase activity, acting on amino acids and derivatives
H9Q78_04345	COG0151	Belongs to the GarS family
H9Q78_04350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9Q78_04355	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9Q78_04360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9Q78_04395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9Q78_04400	COG0167	dihydroorotate dehydrogenase activity
H9Q78_04405	COG0543	2 iron, 2 sulfur cluster binding
H9Q78_04410	COG0284	orotidine-5'-phosphate decarboxylase activity
H9Q78_04415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9Q78_04435	COG0484	heat shock protein binding
H9Q78_04440	COG0443	Heat shock 70 kDa protein
H9Q78_04445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9Q78_04450	COG1420	regulation of RNA biosynthetic process
H9Q78_04460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q78_04465	COG0481	GTPase activity
H9Q78_04475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H9Q78_04480	COG0268	Binds directly to 16S ribosomal RNA
H9Q78_04500	COG1757	Na H antiporter
H9Q78_04515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q78_04550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9Q78_04555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9Q78_04560	COG0733	neurotransmitter:sodium symporter activity
H9Q78_04565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H9Q78_04570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9Q78_04575	COG0137	argininosuccinate synthase activity
H9Q78_04580	COG0598	Magnesium transport protein CorA
H9Q78_04590	COG1217	gtp-binding protein TYPA
H9Q78_04595	COG0668	transmembrane transport
H9Q78_04600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9Q78_04605	COG2059	Chromate
H9Q78_04610	COG2059	Chromate
H9Q78_04630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q78_04635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9Q78_04640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9Q78_04655	COG1349	DNA-binding transcription factor activity
H9Q78_04660	COG0577	efflux transmembrane transporter activity
H9Q78_04665	COG1136	(ABC) transporter
H9Q78_04670	COG2252	PERMEase
H9Q78_04685	COG1122	ATPase activity
H9Q78_04690	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9Q78_04710	COG1131	(ABC) transporter
H9Q78_04745	COG1461	Dihydroxyacetone kinase
H9Q78_04755	COG1595	DNA-templated transcription, initiation
H9Q78_04760	COG1121	(ABC) transporter
H9Q78_04775	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q78_04810	COG0657	acetylesterase activity
H9Q78_04870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q78_04880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9Q78_04895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9Q78_04895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9Q78_04920	COG1691	(AIR) carboxylase
H9Q78_04930	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
H9Q78_04940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q78_04945	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9Q78_04970	COG1971	Probably functions as a manganese efflux pump
H9Q78_04975	COG4806	L-rhamnose isomerase
H9Q78_04980	COG1132	(ABC) transporter
H9Q78_04985	COG1132	(ABC) transporter
H9Q78_04990	COG2204	response regulator
H9Q78_04995	COG1342	Belongs to the UPF0251 family
H9Q78_05005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9Q78_05055	COG0534	Mate efflux family protein
H9Q78_05070	COG0494	nUDIX hydrolase
H9Q78_05080	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9Q78_05095	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_05100	COG1129	ABC transporter
H9Q78_05115	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H9Q78_05125	COG1063	alcohol dehydrogenase
H9Q78_05150	COG1247	-acetyltransferase
H9Q78_05160	COG0583	DNA-binding transcription factor activity
H9Q78_05170	COG0515	serine threonine protein kinase
H9Q78_05180	COG1115	amino acid carrier protein
H9Q78_05200	COG0640	Transcriptional regulator
H9Q78_05225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q78_05230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H9Q78_05240	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q78_05265	COG3437	response regulator, receiver
H9Q78_05280	COG5002	protein histidine kinase activity
H9Q78_05310	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H9Q78_05315	COG1793	dna ligase
H9Q78_05580	COG4974	Belongs to the 'phage' integrase family
H9Q78_05615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9Q78_05625	COG0116	Belongs to the methyltransferase superfamily
H9Q78_05630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9Q78_05645	COG1490	D-aminoacyl-tRNA deacylase activity
H9Q78_05700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q78_05705	COG3958	Transketolase
H9Q78_05710	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q78_05720	COG1609	Transcriptional regulator
H9Q78_05775	COG2226	methyltransferase
H9Q78_05790	COG0456	acetyltransferase
H9Q78_05790	COG0454	-acetyltransferase
H9Q78_05795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9Q78_05810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9Q78_05820	COG1131	(ABC) transporter
H9Q78_05855	COG1234	tRNA 3'-trailer cleavage
H9Q78_05870	COG1214	PFAM Peptidase M22, glycoprotease
H9Q78_05875	COG0802	atpase or kinase
H9Q78_05885	COG2183	response to ionizing radiation
H9Q78_05900	COG0460	homoserine dehydrogenase
H9Q78_05905	COG4492	Belongs to the UPF0735 family
H9Q78_05915	COG0653	protein targeting
H9Q78_05945	COG0492	ferredoxin-NADP+ reductase activity
H9Q78_05970	COG1132	(ABC) transporter
H9Q78_05980	COG0583	DNA-binding transcription factor activity
H9Q78_05985	COG0791	NLP P60 protein
H9Q78_05990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9Q78_06000	COG1129	ABC transporter
H9Q78_06005	COG2972	Histidine kinase
H9Q78_06010	COG2207	Transcriptional regulator
H9Q78_06010	COG4753	response regulator
H9Q78_06015	COG1070	Carbohydrate kinase
H9Q78_06025	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_06030	COG1129	ABC transporter
H9Q78_06040	COG0058	SHG alpha-glucan phosphorylase activity
H9Q78_06060	COG3708	Transcriptional regulator
H9Q78_06060	COG2207	Transcriptional regulator
H9Q78_06065	COG1757	Na H antiporter
H9Q78_06070	COG0686	Belongs to the AlaDH PNT family
H9Q78_06075	COG0733	neurotransmitter:sodium symporter activity
H9Q78_06085	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_06095	COG1070	Carbohydrate kinase
H9Q78_06130	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_06145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q78_06155	COG1929	Belongs to the glycerate kinase type-1 family
H9Q78_06160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q78_06165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q78_06170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q78_06185	COG1131	(ABC) transporter
H9Q78_06205	COG3835	regulator
H9Q78_06215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9Q78_06220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q78_06225	COG1994	Peptidase M50
H9Q78_06245	COG0006	proline dipeptidase activity
H9Q78_06250	COG0133	tryptophan synthase activity
H9Q78_06255	COG0564	pseudouridine synthase activity
H9Q78_06260	COG2723	6-phospho-beta-galactosidase activity
H9Q78_06285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q78_06290	COG0049	tRNA binding
H9Q78_06295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9Q78_06305	COG1187	pseudouridine synthase activity
H9Q78_06315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9Q78_06320	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q78_06335	COG1802	Transcriptional regulator
H9Q78_06340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9Q78_06345	COG1473	amidohydrolase
H9Q78_06350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9Q78_06380	COG4509	Sortase family
H9Q78_06390	COG0534	Mate efflux family protein
H9Q78_06420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q78_06430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q78_06440	COG1022	Amp-dependent synthetase and ligase
H9Q78_06450	COG4191	Histidine kinase
H9Q78_06480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q78_06500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9Q78_06505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9Q78_06510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9Q78_06520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9Q78_06525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q78_06545	COG0463	Glycosyl transferase, family 2
H9Q78_06555	COG0165	Argininosuccinate lyase
H9Q78_06560	COG1070	Carbohydrate kinase
H9Q78_06595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q78_06600	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_06605	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_06615	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_06620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9Q78_06665	COG2172	sigma factor antagonist activity
H9Q78_06670	COG1366	Belongs to the anti-sigma-factor antagonist family
H9Q78_06685	COG0285	dihydrofolate synthase activity
H9Q78_06690	COG0534	Mate efflux family protein
H9Q78_06695	COG0583	DNA-binding transcription factor activity
H9Q78_06700	COG0525	valine-tRNA ligase activity
H9Q78_06720	COG1131	(ABC) transporter
H9Q78_06745	COG0534	Mate efflux family protein
H9Q78_06755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9Q78_06760	COG0085	RNA polymerase activity
H9Q78_06770	COG0534	Mate efflux family protein
H9Q78_06775	COG2116	formate transmembrane transporter activity
H9Q78_06785	COG0343	queuine tRNA-ribosyltransferase activity
H9Q78_06790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q78_06790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q78_06810	COG1253	flavin adenine dinucleotide binding
H9Q78_06830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q78_06850	COG0698	ribose 5-phosphate isomerase
H9Q78_06855	COG2376	Dihydroxyacetone kinase
H9Q78_06860	COG1461	Dihydroxyacetone kinase
H9Q78_06870	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_06875	COG1129	ABC transporter
H9Q78_06880	COG1070	Carbohydrate kinase
H9Q78_06895	COG0436	Aminotransferase
H9Q78_06900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9Q78_06915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9Q78_06925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q78_06930	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9Q78_06945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9Q78_06965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9Q78_06970	COG4106	trans-aconitate 2-methyltransferase activity
H9Q78_06975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9Q78_06990	COG0463	Glycosyl transferase, family 2
H9Q78_07025	COG0028	Belongs to the TPP enzyme family
H9Q78_07040	COG1215	transferase activity, transferring glycosyl groups
H9Q78_07045	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q78_07050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9Q78_07065	COG1216	Glycosyl transferase, family 2
H9Q78_07115	COG0438	transferase activity, transferring glycosyl groups
H9Q78_07115	COG1216	Glycosyl transferase, family 2
H9Q78_07145	COG1216	Glycosyl transferase, family 2
H9Q78_07170	COG3475	LICD family
H9Q78_07175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9Q78_07180	COG0562	UDP-galactopyranose mutase
H9Q78_07185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9Q78_07195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q78_07205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9Q78_07220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9Q78_07225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9Q78_07250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9Q78_07270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q78_07280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q78_07285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q78_07290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9Q78_07290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9Q78_07300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q78_07305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9Q78_07310	COG0028	Belongs to the TPP enzyme family
H9Q78_07315	COG0129	dihydroxy-acid dehydratase activity
H9Q78_07320	COG0473	3-isopropylmalate dehydrogenase activity
H9Q78_07325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9Q78_07335	COG2226	methyltransferase
H9Q78_07340	COG0723	plastoquinol--plastocyanin reductase activity
H9Q78_07340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9Q78_07350	COG1331	Highly conserved protein containing a thioredoxin domain
H9Q78_07355	COG1827	regulation of RNA biosynthetic process
H9Q78_07365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q78_07370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9Q78_07375	COG0037	tRNA processing
H9Q78_07385	COG2208	phosphoserine phosphatase activity
H9Q78_07405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9Q78_07410	COG0776	regulation of translation
H9Q78_07415	COG3956	TIGRFAM MazG family protein
H9Q78_07420	COG2002	toxin-antitoxin pair type II binding
H9Q78_07440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9Q78_07445	COG0193	aminoacyl-tRNA hydrolase activity
H9Q78_07455	COG0569	domain protein
H9Q78_07460	COG2088	sporulation resulting in formation of a cellular spore
H9Q78_07465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9Q78_07470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9Q78_07475	COG0420	3'-5' exonuclease activity
H9Q78_07480	COG4717	serine-type aminopeptidase activity
H9Q78_07485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9Q78_07500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9Q78_07530	COG1120	ATPase activity
H9Q78_07535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q78_07550	COG1132	(ABC) transporter
H9Q78_07555	COG1940	carbohydrate kinase activity
H9Q78_07560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9Q78_07585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9Q78_07600	COG4481	Protein conserved in bacteria
H9Q78_07610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9Q78_07635	COG1368	sulfuric ester hydrolase activity
H9Q78_07640	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9Q78_07645	COG1278	Cold shock
H9Q78_07650	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q78_07655	COG1668	transmembrane transport
H9Q78_07660	COG4152	abc transporter atp-binding protein
H9Q78_07675	COG1609	Transcriptional regulator
H9Q78_07680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q78_07690	COG1869	D-ribose catabolic process
H9Q78_07695	COG1592	Rubrerythrin
H9Q78_07705	COG2378	regulation of single-species biofilm formation
H9Q78_07720	COG0561	phosphatase activity
H9Q78_07745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q78_07755	COG4989	oxidoreductase activity
H9Q78_07760	COG2188	Transcriptional regulator
H9Q78_07770	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_07775	COG1129	ABC transporter
H9Q78_07780	COG2188	Transcriptional regulator
H9Q78_07790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q78_07800	COG0363	glucosamine-6-phosphate deaminase activity
H9Q78_07810	COG0617	tRNA 3'-terminal CCA addition
H9Q78_07815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9Q78_07820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q78_07830	COG0628	permease
H9Q78_07835	COG0745	RESPONSE REGULATOR receiver
H9Q78_07840	COG5002	protein histidine kinase activity
H9Q78_07870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9Q78_07875	COG0084	hydrolase, TatD family'
H9Q78_07910	COG1305	Transglutaminase-like
H9Q78_07920	COG0714	Associated with various cellular activities
H9Q78_07925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9Q78_07935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H9Q78_07940	COG2205	protein histidine kinase activity
H9Q78_07950	COG0546	phosphoglycolate phosphatase activity
H9Q78_07985	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
H9Q78_07995	COG1394	ATPase activity, coupled to movement of substances
H9Q78_08070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q78_08070	COG2190	(PTS) system
H9Q78_08070	COG1263	PTS System
H9Q78_08075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q78_08075	COG1263	PTS System
H9Q78_08075	COG2190	(PTS) system
H9Q78_08080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9Q78_08100	COG3118	belongs to the thioredoxin family
H9Q78_08105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9Q78_08110	COG1686	Belongs to the peptidase S11 family
H9Q78_08115	COG2176	DNA-directed DNA polymerase activity
H9Q78_08120	COG1937	Protein conserved in bacteria
H9Q78_08125	COG3706	GGDEF domain
H9Q78_08140	COG0386	Belongs to the glutathione peroxidase family
H9Q78_08150	COG1476	TRANSCRIPTIONal
H9Q78_08180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9Q78_08185	COG0252	asparaginase activity
H9Q78_08190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9Q78_08195	COG0745	RESPONSE REGULATOR receiver
H9Q78_08200	COG2205	protein histidine kinase activity
H9Q78_08230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q78_08255	COG1475	DNA binding
H9Q78_08260	COG1192	Involved in chromosome partitioning
H9Q78_08275	COG0357	Ribosomal RNA small subunit methyltransferase G
H9Q78_08280	COG0445	tRNA wobble uridine modification
H9Q78_08285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9Q78_08290	COG1847	R3H domain protein
H9Q78_08295	COG0706	membrane insertase activity
H9Q78_08300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9Q78_08305	COG0594	ribonuclease P activity
H9Q78_08310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9Q78_08315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9Q78_08325	COG1187	pseudouridine synthase activity
H9Q78_08330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9Q78_08335	COG0187	DNA topoisomerase II activity
H9Q78_08340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9Q78_08350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H9Q78_08415	COG1609	Transcriptional regulator
H9Q78_08445	COG3681	Belongs to the UPF0597 family
H9Q78_08455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q78_08465	COG0622	Phosphoesterase
H9Q78_08475	COG1982	Orn Lys Arg decarboxylase major
H9Q78_08480	COG0194	GDP metabolic process
H9Q78_08485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9Q78_08490	COG1774	PSP1 C-terminal conserved region
H9Q78_08495	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9Q78_08500	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9Q78_08515	COG0561	phosphatase activity
H9Q78_08520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q78_08525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q78_08530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q78_08540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9Q78_08550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9Q78_08560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9Q78_08565	COG0439	Biotin carboxylase
H9Q78_08575	COG2070	2-Nitropropane dioxygenase
H9Q78_08580	COG1131	(ABC) transporter
H9Q78_08590	COG2715	membrane protein required for spore maturation
H9Q78_08600	COG0784	Response regulator, receiver
H9Q78_08600	COG2205	protein histidine kinase activity
H9Q78_08620	COG1131	(ABC) transporter
H9Q78_08630	COG4585	Histidine kinase
H9Q78_08640	COG1131	(ABC) transporter
H9Q78_08670	COG3546	catalase activity
H9Q78_08690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q78_08780	COG0537	adenosine 5'-monophosphoramidase activity
H9Q78_08785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9Q78_08805	COG0166	Belongs to the GPI family
H9Q78_08830	COG0590	tRNA wobble adenosine to inosine editing
H9Q78_08840	COG2186	Transcriptional regulator
H9Q78_08845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q78_08850	COG2186	Transcriptional regulator
H9Q78_08855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q78_08885	COG0436	Aminotransferase
H9Q78_08895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q78_08910	COG0205	6-phosphofructokinase activity
H9Q78_08915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9Q78_08925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9Q78_08930	COG1687	branched-chain amino acid
H9Q78_08935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H9Q78_08945	COG0561	phosphatase activity
H9Q78_09000	COG2357	RelA SpoT domain protein
H9Q78_09015	COG1151	hydroxylamine reductase activity
H9Q78_09040	COG0735	belongs to the Fur family
H9Q78_09045	COG1773	rubredoxin
H9Q78_09045	COG1592	Rubrerythrin
H9Q78_09050	COG3263	regulation of cellular component size
H9Q78_09060	COG0561	phosphatase activity
H9Q78_09095	COG1136	(ABC) transporter
H9Q78_09105	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9Q78_09110	COG1418	mRNA catabolic process
H9Q78_09115	COG2203	Gaf domain
H9Q78_09115	COG2199	diguanylate cyclase activity
H9Q78_09125	COG1063	alcohol dehydrogenase
H9Q78_09130	COG1129	ABC transporter
H9Q78_09135	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_09145	COG0577	efflux transmembrane transporter activity
H9Q78_09155	COG1136	(ABC) transporter
H9Q78_09170	COG0539	negative regulation of cytoplasmic translation
H9Q78_09175	COG2357	RelA SpoT domain protein
H9Q78_09185	COG1301	dicarboxylic acid transport
H9Q78_09190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9Q78_09200	COG0281	malic enzyme
H9Q78_09205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9Q78_09210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9Q78_09215	COG1129	ABC transporter
H9Q78_09220	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_09225	COG1879	ABC-type sugar transport system periplasmic component
H9Q78_09230	COG2207	Transcriptional regulator
H9Q78_09230	COG4753	response regulator
H9Q78_09230	COG2207	Transcriptional regulator
H9Q78_09230	COG4753	response regulator
H9Q78_09235	COG2972	Histidine kinase
H9Q78_09240	COG1129	ABC transporter
H9Q78_09245	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H9Q78_09250	COG0359	binds to the 23S rRNA
H9Q78_09255	COG0305	Participates in initiation and elongation during chromosome replication
H9Q78_09265	COG0789	Transcriptional regulator
H9Q78_09270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q78_09285	COG4862	establishment of competence for transformation
H9Q78_09295	COG3858	chitin binding
H9Q78_09295	COG1388	LysM domain
H9Q78_09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9Q78_09305	COG0009	L-threonylcarbamoyladenylate synthase
H9Q78_09315	COG0698	ribose 5-phosphate isomerase
H9Q78_09335	COG0356	it plays a direct role in the translocation of protons across the membrane
H9Q78_09340	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9Q78_09345	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9Q78_09350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9Q78_09355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9Q78_09360	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9Q78_09365	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9Q78_09370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9Q78_09375	COG0667	Aldo Keto reductase
H9Q78_09385	COG0071	Belongs to the small heat shock protein (HSP20) family
H9Q78_09405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9Q78_09415	COG0436	Aminotransferase
H9Q78_09425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9Q78_09440	COG1522	sequence-specific DNA binding
H9Q78_09445	COG0436	Aminotransferase
H9Q78_09455	COG3858	chitin binding
H9Q78_09455	COG1388	LysM domain
H9Q78_09460	COG0745	RESPONSE REGULATOR receiver
H9Q78_09465	COG2205	protein histidine kinase activity
H9Q78_09470	COG5002	protein histidine kinase activity
H9Q78_09475	COG0745	RESPONSE REGULATOR receiver
H9Q78_09480	COG1193	negative regulation of DNA recombination
H9Q78_09490	COG3481	metal-dependent phosphohydrolase, HD sub domain
H9Q78_09495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q78_09530	COG1518	maintenance of DNA repeat elements
H9Q78_09555	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H9Q78_09565	COG0428	transporter
H9Q78_09585	COG0069	glutamate synthase activity
H9Q78_09600	COG3437	response regulator, receiver
H9Q78_09630	COG0488	(ABC) transporter
H9Q78_09645	COG2207	Transcriptional regulator
H9Q78_09645	COG1917	Cupin 2, conserved barrel domain protein
H9Q78_09650	COG0697	spore germination
H9Q78_09655	COG1609	Transcriptional regulator
H9Q78_09665	COG1077	Cell shape determining protein MreB Mrl
H9Q78_09670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9Q78_09675	COG1040	competence protein
H9Q78_09680	COG2385	sporulation resulting in formation of a cellular spore
H9Q78_09700	COG0693	protein deglycase activity
H9Q78_09705	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9Q78_09715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9Q78_09720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9Q78_09725	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9Q78_09740	COG3853	Toxic anion resistance protein (TelA)
H9Q78_09750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9Q78_09755	COG0254	rRNA binding
H9Q78_09760	COG3872	metal-dependent enzyme
H9Q78_09765	COG2890	protein-(glutamine-N5) methyltransferase activity
H9Q78_09770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9Q78_09780	COG1757	Na H antiporter
H9Q78_09785	COG0432	Pfam Uncharacterised protein family UPF0047
H9Q78_09790	COG1012	belongs to the aldehyde dehydrogenase family
H9Q78_09825	COG0628	permease
H9Q78_09830	COG0010	Belongs to the arginase family
H9Q78_09835	COG1473	amidohydrolase
H9Q78_09860	COG1228	amidohydrolase
H9Q78_09865	COG0583	DNA-binding transcription factor activity
H9Q78_09880	COG0542	response to heat
H9Q78_09890	COG0726	polysaccharide deacetylase
H9Q78_09895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9Q78_09900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9Q78_09930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9Q78_09940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q78_09950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q78_09975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9Q78_09980	COG5002	protein histidine kinase activity
H9Q78_09985	COG0745	RESPONSE REGULATOR receiver
H9Q78_10010	COG1136	(ABC) transporter
H9Q78_10020	COG2217	Heavy metal translocating P-type atpase
H9Q78_10040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9Q78_10045	COG0058	SHG alpha-glucan phosphorylase activity
H9Q78_10050	COG2239	Acts as a magnesium transporter
H9Q78_10055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q78_10065	COG0250	Participates in transcription elongation, termination and antitermination
H9Q78_10075	COG0081	regulation of translation
H9Q78_10085	COG0222	ribosome binding
H9Q78_10090	COG1609	Transcriptional regulator
H9Q78_10095	COG2376	Dihydroxyacetone kinase
H9Q78_10115	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H9Q78_10125	COG5001	Diguanylate cyclase
H9Q78_10125	COG3706	GGDEF domain
H9Q78_10125	COG2203	Gaf domain
H9Q78_10125	COG4251	negative regulation of phosphorylation
H9Q78_10140	COG0784	Response regulator, receiver
H9Q78_10140	COG2198	Histidine kinase
H9Q78_10140	COG2205	protein histidine kinase activity
H9Q78_10165	COG1785	Belongs to the alkaline phosphatase family
H9Q78_10195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9Q78_10200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9Q78_10210	COG0745	RESPONSE REGULATOR receiver
H9Q78_10215	COG0642	Histidine kinase
H9Q78_10220	COG1136	(ABC) transporter
H9Q78_10230	COG2365	Tyrosine phosphatase family
H9Q78_10235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9Q78_10250	COG1349	DNA-binding transcription factor activity
H9Q78_10255	COG0235	Class ii aldolase
H9Q78_10260	COG1070	Carbohydrate kinase
H9Q78_10265	COG0698	ribose 5-phosphate isomerase
H9Q78_10270	COG0656	L-ascorbic acid biosynthetic process
H9Q78_10275	COG2226	methyltransferase
H9Q78_10280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9Q78_10285	COG0574	Belongs to the PEP-utilizing enzyme family
H9Q78_10285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9Q78_10290	COG1073	alpha beta
H9Q78_10300	COG1396	sequence-specific DNA binding
H9Q78_10310	COG0402	S-adenosylhomocysteine deaminase activity
H9Q78_10325	COG3901	Regulator of nitric oxide reductase transcription
H9Q78_10325	COG0348	domain, Protein
H9Q78_10335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9Q78_10340	COG0110	maltose O-acetyltransferase activity
H9Q78_10375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q78_10380	COG1739	Uncharacterized protein family UPF0029
H9Q78_10385	COG0300	oxidoreductase activity
H9Q78_10400	COG0116	Belongs to the methyltransferase superfamily
H9Q78_10400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9Q78_10405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9Q78_10415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9Q78_10425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q78_10440	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H9Q78_10445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H9Q78_10465	COG0051	transcription antitermination factor activity, RNA binding
H9Q78_10470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9Q78_10475	COG0088	Forms part of the polypeptide exit tunnel
H9Q78_10485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9Q78_10495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9Q78_10505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9Q78_10510	COG0255	Belongs to the universal ribosomal protein uL29 family
H9Q78_10515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9Q78_10535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q78_10540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9Q78_10545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9Q78_10550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9Q78_10555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9Q78_10560	COG1841	ribosomal large subunit assembly
H9Q78_10575	COG0563	adenylate kinase activity
H9Q78_10590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9Q78_10595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9Q78_10600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9Q78_10605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9Q78_10610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9Q78_10615	COG0202	RNA polymerase activity
H9Q78_10620	COG0203	ribosomal protein L17
H9Q78_10635	COG4214	carbohydrate transport
H9Q78_10645	COG1129	ABC transporter
H9Q78_10660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q78_10665	COG1349	DNA-binding transcription factor activity
H9Q78_10675	COG1063	alcohol dehydrogenase
H9Q78_10680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9Q78_10700	COG1129	ABC transporter
H9Q78_10705	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_10725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q78_10735	COG0832	Belongs to the urease beta subunit family
H9Q78_10745	COG1122	ATPase activity
H9Q78_10755	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9Q78_10770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9Q78_10775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9Q78_10780	COG1192	Involved in chromosome partitioning
H9Q78_10785	COG1475	DNA binding
H9Q78_10835	COG2226	methyltransferase
H9Q78_10870	COG1484	DNA-dependent DNA replication
H9Q78_10935	COG0551	DNA topoisomerase type I activity
H9Q78_10935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q78_10975	COG0295	cytidine deaminase activity
H9Q78_11000	COG0358	DNA primase activity
H9Q78_11065	COG1129	ABC transporter
H9Q78_11070	COG1132	(ABC) transporter
H9Q78_11075	COG1132	(ABC) transporter
H9Q78_11105	COG4974	Belongs to the 'phage' integrase family
H9Q78_11110	COG2205	protein histidine kinase activity
H9Q78_11110	COG0784	Response regulator, receiver
H9Q78_11125	COG3437	response regulator, receiver
H9Q78_11130	COG2205	protein histidine kinase activity
H9Q78_11130	COG2198	Histidine kinase
H9Q78_11130	COG0784	Response regulator, receiver
H9Q78_11135	COG0784	Response regulator, receiver
H9Q78_11135	COG2205	protein histidine kinase activity
H9Q78_11145	COG0789	Transcriptional regulator
H9Q78_11165	COG0789	Transcriptional regulator
H9Q78_11180	COG1131	(ABC) transporter
H9Q78_11190	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_11195	COG1773	rubredoxin
H9Q78_11195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H9Q78_11205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9Q78_11235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9Q78_11240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H9Q78_11255	COG0039	L-malate dehydrogenase activity
H9Q78_11270	COG0534	Mate efflux family protein
H9Q78_11275	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q78_11280	COG2205	protein histidine kinase activity
H9Q78_11280	COG0784	Response regulator, receiver
H9Q78_11285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q78_11295	COG0559	Belongs to the binding-protein-dependent transport system permease family
H9Q78_11315	COG0436	Aminotransferase
H9Q78_11320	COG2508	Transcriptional regulator
H9Q78_11330	COG0583	DNA-binding transcription factor activity
H9Q78_11355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9Q78_11370	COG0824	Thioesterase
H9Q78_11380	COG1970	mechanosensitive ion channel activity
H9Q78_11390	COG0747	negative chemotaxis
H9Q78_11400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q78_11405	COG4172	Belongs to the ABC transporter superfamily
H9Q78_11410	COG4608	Belongs to the ABC transporter superfamily
H9Q78_11425	COG0534	Mate efflux family protein
H9Q78_11430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9Q78_11445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q78_11450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H9Q78_11470	COG0504	CTP synthase activity
H9Q78_11475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q78_11485	COG0322	excinuclease ABC activity
H9Q78_11490	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9Q78_11500	COG1481	regulation of sporulation
H9Q78_11505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q78_11520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9Q78_11525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q78_11530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q78_11535	COG0124	histidyl-tRNA synthetase
H9Q78_11540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9Q78_11545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9Q78_11555	COG1393	Belongs to the ArsC family
H9Q78_11575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H9Q78_11580	COG0542	response to heat
H9Q78_11590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9Q78_11595	COG1971	Probably functions as a manganese efflux pump
H9Q78_11600	COG0561	phosphatase activity
H9Q78_11615	COG1396	sequence-specific DNA binding
H9Q78_11620	COG3842	ATPase activity
H9Q78_11625	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9Q78_11630	COG1177	transmembrane transport
H9Q78_11650	COG2199	diguanylate cyclase activity
H9Q78_11655	COG2032	superoxide dismutase activity
H9Q78_11660	COG3546	catalase activity
H9Q78_11680	COG0583	DNA-binding transcription factor activity
H9Q78_11685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9Q78_11705	COG0113	porphobilinogen synthase activity
H9Q78_11710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9Q78_11715	COG0006	proline dipeptidase activity
H9Q78_11745	COG3842	ATPase activity
H9Q78_11750	COG3835	regulator
H9Q78_11755	COG2884	Cell division ATP-binding protein ftsE
H9Q78_11760	COG2177	Part of the ABC transporter FtsEX involved in
H9Q78_11765	COG0739	heme binding
H9Q78_11770	COG0793	Belongs to the peptidase S41A family
H9Q78_11785	COG0778	Nitroreductase
H9Q78_11810	COG0588	phosphoglycerate mutase activity
H9Q78_11945	COG0745	RESPONSE REGULATOR receiver
H9Q78_11950	COG2205	protein histidine kinase activity
H9Q78_11955	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q78_11960	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
H9Q78_11965	COG3708	Transcriptional regulator
H9Q78_11965	COG2207	Transcriptional regulator
H9Q78_11985	COG1051	belongs to the nudix hydrolase family
H9Q78_11995	COG0110	maltose O-acetyltransferase activity
H9Q78_12000	COG1733	regulation of RNA biosynthetic process
H9Q78_12005	COG2910	NAD(P)H-binding
H9Q78_12045	COG0789	Transcriptional regulator
H9Q78_12065	COG2814	Major facilitator Superfamily
H9Q78_12075	COG1309	transcriptional regulator
H9Q78_12080	COG2814	Major facilitator Superfamily
H9Q78_12090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9Q78_12100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9Q78_12105	COG1940	carbohydrate kinase activity
H9Q78_12110	COG1063	alcohol dehydrogenase
H9Q78_12115	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_12125	COG0285	dihydrofolate synthase activity
H9Q78_12135	COG1418	mRNA catabolic process
H9Q78_12140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9Q78_12145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9Q78_12145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9Q78_12150	COG0077	Prephenate dehydratase
H9Q78_12150	COG1605	Chorismate mutase
H9Q78_12165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9Q78_12190	COG0488	(ABC) transporter
H9Q78_12195	COG0708	Exodeoxyribonuclease III
H9Q78_12200	COG0488	(ABC) transporter
H9Q78_12205	COG1523	belongs to the glycosyl hydrolase 13 family
H9Q78_12240	COG0789	Transcriptional regulator
H9Q78_12245	COG1854	S-ribosylhomocysteine lyase activity
H9Q78_12255	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9Q78_12265	COG2357	RelA SpoT domain protein
H9Q78_12270	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H9Q78_12275	COG1074	ATP-dependent DNA helicase activity
H9Q78_12285	COG0436	Aminotransferase
H9Q78_12330	COG0733	neurotransmitter:sodium symporter activity
H9Q78_12345	COG0456	acetyltransferase
H9Q78_12350	COG2188	Transcriptional regulator
H9Q78_12375	COG2873	o-acetylhomoserine
H9Q78_12385	COG1959	2 iron, 2 sulfur cluster binding
H9Q78_12395	COG3870	Protein conserved in bacteria
H9Q78_12405	COG0534	Mate efflux family protein
H9Q78_12410	COG0352	thiamine-phosphate diphosphorylase activity
H9Q78_12415	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H9Q78_12420	COG0351	phosphomethylpyrimidine kinase
H9Q78_12430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9Q78_12450	COG0346	lactoylglutathione lyase activity
H9Q78_12470	COG1215	transferase activity, transferring glycosyl groups
H9Q78_12475	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q78_12480	COG3958	Transketolase
H9Q78_12490	COG0673	inositol 2-dehydrogenase activity
H9Q78_12500	COG0656	L-ascorbic acid biosynthetic process
H9Q78_12515	COG1349	DNA-binding transcription factor activity
H9Q78_12520	COG1082	Xylose isomerase domain protein TIM barrel
H9Q78_12525	COG1129	ABC transporter
H9Q78_12530	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_12555	COG1070	Carbohydrate kinase
H9Q78_12565	COG0235	Class ii aldolase
H9Q78_12570	COG1070	Carbohydrate kinase
H9Q78_12580	COG0789	Transcriptional regulator
H9Q78_12590	COG1268	BioY protein
H9Q78_12610	COG0528	UMP kinase activity
H9Q78_12615	COG0233	cytoplasmic translational termination
H9Q78_12625	COG4589	Belongs to the CDS family
H9Q78_12635	COG0750	zinc metalloprotease
H9Q78_12640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9Q78_12650	COG1937	Protein conserved in bacteria
H9Q78_12680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q78_12700	COG0779	Required for maturation of 30S ribosomal subunits
H9Q78_12705	COG0195	Participates in both transcription termination and antitermination
H9Q78_12710	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H9Q78_12720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9Q78_12720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9Q78_12725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9Q78_12730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9Q78_12735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9Q78_12740	COG0196	riboflavin kinase activity
H9Q78_12745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9Q78_12750	COG1185	polyribonucleotide nucleotidyltransferase activity
H9Q78_12770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9Q78_12775	COG0583	DNA-binding transcription factor activity
H9Q78_12795	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9Q78_12805	COG0656	L-ascorbic acid biosynthetic process
H9Q78_12820	COG0583	DNA-binding transcription factor activity
H9Q78_12845	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_12855	COG0765	amino acid transport
H9Q78_12860	COG1126	abc transporter atp-binding protein
H9Q78_12865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q78_12885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9Q78_12900	COG1979	alcohol dehydrogenase
H9Q78_12910	COG4895	conserved protein (DUF2196)
H9Q78_12915	COG0753	catalase activity
H9Q78_12930	COG0745	RESPONSE REGULATOR receiver
H9Q78_12945	COG3279	Response regulator of the LytR AlgR family
H9Q78_12960	COG1366	Belongs to the anti-sigma-factor antagonist family
H9Q78_12975	COG2770	Histidine kinase
H9Q78_12975	COG2208	phosphoserine phosphatase activity
H9Q78_13005	COG2274	protein secretion by the type I secretion system
H9Q78_13045	COG0454	-acetyltransferase
H9Q78_13050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q78_13070	COG2226	methyltransferase
H9Q78_13080	COG2205	protein histidine kinase activity
H9Q78_13080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q78_13095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q78_13095	COG1918	ferrous iron import across plasma membrane
H9Q78_13105	COG4978	Transcriptional regulator
H9Q78_13105	COG0789	Transcriptional regulator
H9Q78_13120	COG3304	Inner membrane component domain
H9Q78_13125	COG1187	pseudouridine synthase activity
H9Q78_13130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9Q78_13155	COG1959	2 iron, 2 sulfur cluster binding
H9Q78_13165	COG0822	iron-sulfur transferase activity
H9Q78_13170	COG0482	sulfurtransferase activity
H9Q78_13185	COG3706	GGDEF domain
H9Q78_13200	COG0737	Belongs to the 5'-nucleotidase family
H9Q78_13205	COG0784	Response regulator, receiver
H9Q78_13205	COG2205	protein histidine kinase activity
H9Q78_13230	COG1309	transcriptional regulator
H9Q78_13245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q78_13255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9Q78_13255	COG0646	methionine synthase
H9Q78_13265	COG1131	(ABC) transporter
H9Q78_13275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q78_13285	COG0745	RESPONSE REGULATOR receiver
H9Q78_13290	COG2205	protein histidine kinase activity
H9Q78_13295	COG1131	(ABC) transporter
H9Q78_13320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9Q78_13325	COG1116	anion transmembrane transporter activity
H9Q78_13330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9Q78_13335	COG1160	GTP binding
H9Q78_13345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9Q78_13360	COG0149	triose-phosphate isomerase activity
H9Q78_13370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9Q78_13380	COG2378	regulation of single-species biofilm formation
H9Q78_13390	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q78_13425	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q78_13440	COG2414	aldehyde ferredoxin oxidoreductase
H9Q78_13470	COG1309	transcriptional regulator
H9Q78_13475	COG0534	Mate efflux family protein
H9Q78_13480	COG0583	DNA-binding transcription factor activity
H9Q78_13490	COG1129	ABC transporter
H9Q78_13495	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_13500	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q78_13530	COG0460	homoserine dehydrogenase
H9Q78_13540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9Q78_13540	COG0512	Glutamine amidotransferase of anthranilate synthase
H9Q78_13545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9Q78_13550	COG0134	indole-3-glycerol-phosphate synthase activity
H9Q78_13555	COG0135	phosphoribosylanthranilate isomerase activity
H9Q78_13560	COG0133	tryptophan synthase activity
H9Q78_13565	COG0159	tryptophan synthase activity
H9Q78_13570	COG1597	lipid kinase activity
H9Q78_13575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q78_13590	COG0070	glutamate synthase
H9Q78_13590	COG0069	glutamate synthase activity
H9Q78_13590	COG0067	glutamate synthase
H9Q78_13595	COG0493	'glutamate synthase
H9Q78_13600	COG1136	(ABC) transporter
H9Q78_13630	COG1164	Oligoendopeptidase f
H9Q78_13675	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H9Q78_13685	COG1309	transcriptional regulator
H9Q78_13690	COG1131	(ABC) transporter
H9Q78_13700	COG1309	transcriptional regulator
H9Q78_13720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9Q78_13730	COG1136	(ABC) transporter
H9Q78_13735	COG2205	protein histidine kinase activity
H9Q78_13740	COG0745	RESPONSE REGULATOR receiver
H9Q78_13755	COG4806	L-rhamnose isomerase
H9Q78_13760	COG1082	Xylose isomerase domain protein TIM barrel
H9Q78_13780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9Q78_13790	COG2212	antiporter activity
H9Q78_13810	COG1006	Multisubunit Na H antiporter MnhC subunit
H9Q78_13815	COG0651	ATP synthesis coupled electron transport
H9Q78_13820	COG0651	ATP synthesis coupled electron transport
H9Q78_13825	COG0651	ATP synthesis coupled electron transport
H9Q78_13830	COG0651	ATP synthesis coupled electron transport
H9Q78_13835	COG4974	Belongs to the 'phage' integrase family
H9Q78_13865	COG4509	Sortase family
H9Q78_13895	COG0745	RESPONSE REGULATOR receiver
H9Q78_13910	COG0667	Aldo Keto reductase
H9Q78_13930	COG1979	alcohol dehydrogenase
H9Q78_13935	COG0789	Transcriptional regulator
H9Q78_13945	COG0583	DNA-binding transcription factor activity
H9Q78_13955	COG0513	Belongs to the DEAD box helicase family
H9Q78_13965	COG0287	Prephenate dehydrogenase
H9Q78_13970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9Q78_13975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q78_13995	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
H9Q78_14010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9Q78_14015	COG1404	Belongs to the peptidase S8 family
H9Q78_14025	COG0733	neurotransmitter:sodium symporter activity
H9Q78_14030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9Q78_14035	COG0358	DNA primase activity
H9Q78_14040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q78_14045	COG2384	SAM-dependent methyltransferase
H9Q78_14050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9Q78_14075	COG0756	dUTP diphosphatase activity
H9Q78_14090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9Q78_14095	COG1328	CTP reductase activity
H9Q78_14095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9Q78_14105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9Q78_14115	COG1773	rubredoxin
H9Q78_14125	COG0426	domain, Protein
H9Q78_14130	COG0534	Mate efflux family protein
H9Q78_14160	COG2385	sporulation resulting in formation of a cellular spore
H9Q78_14170	COG0205	6-phosphofructokinase activity
H9Q78_14175	COG0538	isocitrate dehydrogenase activity
H9Q78_14180	COG1404	Belongs to the peptidase S8 family
H9Q78_14190	COG0488	(ABC) transporter
H9Q78_14195	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H9Q78_14200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9Q78_14200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9Q78_14205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q78_14210	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9Q78_14215	COG1253	flavin adenine dinucleotide binding
H9Q78_14220	COG0534	Mate efflux family protein
H9Q78_14225	COG0217	transcriptional regulatory protein
H9Q78_14235	COG0252	asparaginase activity
H9Q78_14255	COG0745	RESPONSE REGULATOR receiver
H9Q78_14260	COG5002	protein histidine kinase activity
H9Q78_14265	COG3906	Belongs to the UPF0473 family
H9Q78_14270	COG0012	GTP binding
H9Q78_14280	COG2001	Belongs to the MraZ family
H9Q78_14295	COG0768	penicillin binding
H9Q78_14300	COG0768	penicillin binding
H9Q78_14305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9Q78_14310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9Q78_14315	COG0772	Belongs to the SEDS family
H9Q78_14325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9Q78_14340	COG0765	amino acid transport
H9Q78_14345	COG1126	abc transporter atp-binding protein
H9Q78_14350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q78_14355	COG0436	Aminotransferase
H9Q78_14360	COG2508	Transcriptional regulator
H9Q78_14365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9Q78_14370	COG2972	Histidine kinase
H9Q78_14375	COG3279	Response regulator of the LytR AlgR family
H9Q78_14380	COG1191	sigma factor activity
H9Q78_14395	COG1191	sigma factor activity
H9Q78_14400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q78_14405	COG0551	DNA topoisomerase type I activity
H9Q78_14405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q78_14410	COG2246	polysaccharide biosynthetic process
H9Q78_14420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)