locus-tag	class	description
C7M35_00001	COG1136	(ABC) transporter
C7M35_00001	COG0577	efflux transmembrane transporter activity
C7M35_00005	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M35_00006	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_00007	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_00008	COG2723	6-phospho-beta-galactosidase activity
C7M35_00011	COG1376	ErfK ybiS ycfS ynhG family protein
C7M35_00012	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M35_00013	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M35_00015	COG0436	Aminotransferase
C7M35_00016	COG1438	arginine binding
C7M35_00018	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M35_00019	COG3679	Belongs to the UPF0342 family
C7M35_00020	COG0420	3'-5' exonuclease activity
C7M35_00021	COG4717	serine-type aminopeptidase activity
C7M35_00022	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M35_00026	COG0583	DNA-binding transcription factor activity
C7M35_00028	COG0431	NADPH-dependent FMN reductase
C7M35_00028	COG1053	succinate dehydrogenase
C7M35_00028	COG3976	FMN-binding domain protein
C7M35_00036	COG2217	Heavy metal translocating P-type atpase
C7M35_00037	COG0148	phosphopyruvate hydratase activity
C7M35_00039	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M35_00040	COG0463	Glycosyl transferase, family 2
C7M35_00044	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M35_00044	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M35_00045	COG0307	riboflavin synthase, alpha
C7M35_00046	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M35_00046	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M35_00047	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M35_00050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M35_00052	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_00058	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M35_00060	COG0537	adenosine 5'-monophosphoramidase activity
C7M35_00061	COG1131	(ABC) transporter
C7M35_00062	COG4473	ABC transporter
C7M35_00063	COG0510	thiamine kinase activity
C7M35_00064	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M35_00066	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M35_00067	COG1674	ftsk spoiiie
C7M35_00068	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M35_00073	COG0719	Fe-S assembly protein
C7M35_00074	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M35_00076	COG0719	Fe-S assembly protein
C7M35_00077	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M35_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M35_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M35_00081	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M35_00082	COG0237	dephospho-CoA kinase activity
C7M35_00083	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M35_00084	COG3611	Membrane attachment protein
C7M35_00085	COG1484	DNA-dependent DNA replication
C7M35_00086	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M35_00087	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M35_00088	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M35_00089	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M35_00091	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M35_00092	COG0604	alcohol dehydrogenase
C7M35_00093	COG1733	regulation of RNA biosynthetic process
C7M35_00095	COG1215	transferase activity, transferring glycosyl groups
C7M35_00098	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M35_00099	COG1534	Rna-binding protein
C7M35_00100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M35_00101	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M35_00102	COG0799	negative regulation of ribosome biogenesis
C7M35_00103	COG2226	methyltransferase
C7M35_00104	COG1323	Belongs to the UPF0348 family
C7M35_00108	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M35_00109	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M35_00110	COG0745	RESPONSE REGULATOR receiver
C7M35_00111	COG5002	protein histidine kinase activity
C7M35_00113	COG0419	ATPase involved in DNA repair
C7M35_00116	COG0706	membrane insertase activity
C7M35_00117	COG1254	Belongs to the acylphosphatase family
C7M35_00118	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M35_00120	COG1733	regulation of RNA biosynthetic process
C7M35_00121	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M35_00122	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M35_00122	COG0072	phenylalanine-tRNA ligase activity
C7M35_00123	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M35_00124	COG0572	uridine kinase
C7M35_00125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M35_00128	COG4841	protein insertion into membrane
C7M35_00130	COG0768	penicillin binding
C7M35_00131	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M35_00132	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M35_00133	COG0705	Rhomboid family
C7M35_00133	COG0457	Tetratricopeptide repeat
C7M35_00135	COG1940	carbohydrate kinase activity
C7M35_00139	COG0584	glycerophosphoryl diester phosphodiesterase
C7M35_00140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M35_00141	COG0789	Transcriptional regulator
C7M35_00153	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M35_00155	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M35_00156	COG0006	proline dipeptidase activity
C7M35_00157	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M35_00158	COG1302	Protein conserved in bacteria
C7M35_00159	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M35_00160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M35_00161	COG1570	exodeoxyribonuclease VII activity
C7M35_00162	COG1722	exodeoxyribonuclease VII activity
C7M35_00163	COG0142	geranyltranstransferase activity
C7M35_00164	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M35_00165	COG1438	arginine binding
C7M35_00166	COG0497	DNA recombination
C7M35_00169	COG1732	Glycine betaine
C7M35_00172	COG0194	GDP metabolic process
C7M35_00173	COG1758	RNA polymerase activity
C7M35_00174	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M35_00175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M35_00176	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M35_00177	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M35_00177	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M35_00178	COG0631	protein serine/threonine phosphatase activity
C7M35_00179	COG0515	serine threonine protein kinase
C7M35_00179	COG2815	serine threonine protein kinase
C7M35_00180	COG1162	GTPase activity
C7M35_00181	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M35_00182	COG1564	THIamine pyrophosphokinase
C7M35_00183	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M35_00184	COG1302	Protein conserved in bacteria
C7M35_00185	COG1461	Dihydroxyacetone kinase
C7M35_00186	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M35_00187	COG0416	fatty acid biosynthetic process
C7M35_00188	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M35_00189	COG0571	ribonuclease III activity
C7M35_00190	COG1196	nuclear chromosome segregation
C7M35_00191	COG0552	protein localization to endoplasmic reticulum
C7M35_00192	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M35_00193	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M35_00194	COG0228	four-way junction DNA binding
C7M35_00195	COG1837	Belongs to the UPF0109 family
C7M35_00196	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M35_00197	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M35_00198	COG0335	large ribosomal subunit rRNA binding
C7M35_00202	COG1131	(ABC) transporter
C7M35_00206	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M35_00206	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M35_00207	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M35_00208	COG0134	indole-3-glycerol-phosphate synthase activity
C7M35_00209	COG0135	phosphoribosylanthranilate isomerase activity
C7M35_00210	COG0133	tryptophan synthase activity
C7M35_00211	COG0159	tryptophan synthase activity
C7M35_00213	COG3293	Transposase
C7M35_00216	COG1063	alcohol dehydrogenase
C7M35_00219	COG0300	oxidoreductase activity
C7M35_00221	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M35_00222	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M35_00223	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M35_00224	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M35_00225	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_00226	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M35_00229	COG0439	Biotin carboxylase
C7M35_00232	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M35_00234	COG1811	Na channel or pump
C7M35_00235	COG0583	DNA-binding transcription factor activity
C7M35_00236	COG1607	acyl-coa hydrolase
C7M35_00237	COG1162	GTPase activity
C7M35_00239	COG0477	Major facilitator Superfamily
C7M35_00243	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7M35_00244	COG3397	chitin binding
C7M35_00247	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M35_00249	COG3152	Membrane
C7M35_00250	COG1597	lipid kinase activity
C7M35_00253	COG2261	transglycosylase associated protein
C7M35_00254	COG3237	CsbD-like
C7M35_00257	COG1942	4-Oxalocrotonate Tautomerase
C7M35_00264	COG0531	amino acid
C7M35_00265	COG0561	phosphatase activity
C7M35_00266	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M35_00266	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7M35_00270	COG2017	converts alpha-aldose to the beta-anomer
C7M35_00271	COG1304	FMN binding
C7M35_00275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M35_00275	COG1199	ATP-dependent helicase activity
C7M35_00278	COG0017	Asparaginyl-tRNA synthetase
C7M35_00281	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M35_00282	COG2011	ABC-type metal ion transport system permease component
C7M35_00283	COG1464	Belongs to the NlpA lipoprotein family
C7M35_00285	COG1177	transmembrane transport
C7M35_00286	COG1840	ABC-type Fe3 transport system, periplasmic component
C7M35_00290	COG3331	DNA recombination
C7M35_00291	COG4474	Belongs to the UPF0398 family
C7M35_00292	COG3599	regulation of cell shape
C7M35_00294	COG0116	Belongs to the methyltransferase superfamily
C7M35_00297	COG0477	Major facilitator Superfamily
C7M35_00298	COG1073	alpha beta
C7M35_00300	COG1216	Glycosyl transferase, family 2
C7M35_00304	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M35_00309	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M35_00312	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7M35_00313	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M35_00314	COG0564	pseudouridine synthase activity
C7M35_00315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M35_00316	COG0505	Belongs to the CarA family
C7M35_00317	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M35_00319	COG5646	InterPro IPR014922
C7M35_00326	COG1131	(ABC) transporter
C7M35_00327	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M35_00328	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7M35_00330	COG1307	EDD domain protein, DegV family
C7M35_00341	COG1113	amino acid transport
C7M35_00344	COG1620	l-lactate permease
C7M35_00346	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M35_00348	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M35_00351	COG1846	Transcriptional regulator
C7M35_00352	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M35_00359	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M35_00360	COG1227	inorganic diphosphatase activity
C7M35_00361	COG0583	DNA-binding transcription factor activity
C7M35_00363	COG0187	DNA topoisomerase II activity
C7M35_00364	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M35_00366	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M35_00367	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M35_00368	COG4974	Belongs to the 'phage' integrase family
C7M35_00369	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M35_00370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M35_00371	COG0758	DNA mediated transformation
C7M35_00372	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M35_00373	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M35_00375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M35_00376	COG0583	DNA-binding transcription factor activity
C7M35_00380	COG2814	Major facilitator Superfamily
C7M35_00381	COG0793	Belongs to the peptidase S41A family
C7M35_00381	COG3409	Peptidoglycan-binding domain 1 protein
C7M35_00382	COG4479	Belongs to the UPF0346 family
C7M35_00383	COG4698	Protein conserved in bacteria
C7M35_00384	COG2755	lipolytic protein G-D-S-L family
C7M35_00385	COG1307	EDD domain protein, DegV family
C7M35_00387	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M35_00388	COG0488	(ABC) transporter
C7M35_00390	COG0617	tRNA 3'-terminal CCA addition
C7M35_00391	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M35_00392	COG0561	phosphatase activity
C7M35_00393	COG0457	Tetratricopeptide repeat
C7M35_00395	COG1160	GTP binding
C7M35_00396	COG0539	negative regulation of cytoplasmic translation
C7M35_00397	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M35_00399	COG0514	ATP-dependent DNA helicase (RecQ)
C7M35_00401	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M35_00402	COG1187	pseudouridine synthase activity
C7M35_00403	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M35_00404	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M35_00406	COG4974	Belongs to the 'phage' integrase family
C7M35_00407	COG2996	Protein conserved in bacteria
C7M35_00410	COG0205	6-phosphofructokinase activity
C7M35_00411	COG0587	DNA-directed DNA polymerase activity
C7M35_00413	COG0542	response to heat
C7M35_00415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M35_00416	COG2384	SAM-dependent methyltransferase
C7M35_00422	COG0574	Belongs to the PEP-utilizing enzyme family
C7M35_00422	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M35_00424	COG1846	Transcriptional regulator
C7M35_00429	COG2217	Heavy metal translocating P-type atpase
C7M35_00430	COG0148	phosphopyruvate hydratase activity
C7M35_00431	COG0477	Major facilitator Superfamily
C7M35_00433	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M35_00434	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_00435	COG1349	DNA-binding transcription factor activity
C7M35_00437	COG1393	Belongs to the ArsC family
C7M35_00441	COG0546	phosphoglycolate phosphatase activity
C7M35_00447	COG0583	DNA-binding transcription factor activity
C7M35_00448	COG0604	alcohol dehydrogenase
C7M35_00450	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_00451	COG2197	response regulator
C7M35_00452	COG4585	Histidine kinase
C7M35_00454	COG1131	(ABC) transporter
C7M35_00456	COG0519	Catalyzes the synthesis of GMP from XMP
C7M35_00459	COG1131	(ABC) transporter
C7M35_00463	COG1131	(ABC) transporter
C7M35_00464	COG1725	Transcriptional regulator
C7M35_00465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M35_00466	COG0358	DNA primase activity
C7M35_00467	COG0751	glycine-tRNA ligase activity
C7M35_00468	COG0752	glycyl-tRNA synthetase alpha subunit
C7M35_00469	COG1381	Involved in DNA repair and RecF pathway recombination
C7M35_00470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M35_00471	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M35_00472	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M35_00473	COG1702	phosphate starvation-inducible protein PhoH
C7M35_00475	COG1610	YqeY-like protein
C7M35_00476	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M35_00477	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M35_00478	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_00479	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M35_00481	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M35_00483	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M35_00484	COG0124	histidyl-tRNA synthetase
C7M35_00485	COG3103	Sh3 type 3 domain protein
C7M35_00485	COG4991	sh3 domain protein
C7M35_00485	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M35_00486	COG3001	Fructosamine kinase
C7M35_00487	COG0546	phosphoglycolate phosphatase activity
C7M35_00488	COG1490	D-aminoacyl-tRNA deacylase activity
C7M35_00489	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M35_00491	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M35_00492	COG2264	protein methyltransferase activity
C7M35_00493	COG2094	Belongs to the DNA glycosylase MPG family
C7M35_00498	COG0582	viral genome integration into host DNA
C7M35_00499	COG0481	GTPase activity
C7M35_00500	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M35_00501	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M35_00502	COG1696	Membrane protein involved in D-alanine export
C7M35_00503	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M35_00505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M35_00506	COG0484	heat shock protein binding
C7M35_00507	COG0443	Heat shock 70 kDa protein
C7M35_00508	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M35_00509	COG1420	regulation of RNA biosynthetic process
C7M35_00510	COG3527	Alpha-acetolactate decarboxylase
C7M35_00511	COG0196	riboflavin kinase activity
C7M35_00512	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M35_00513	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M35_00514	COG0287	Prephenate dehydrogenase
C7M35_00515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M35_00517	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M35_00518	COG0738	Major facilitator superfamily
C7M35_00519	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M35_00520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M35_00522	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M35_00523	COG0195	Participates in both transcription termination and antitermination
C7M35_00524	COG0779	Required for maturation of 30S ribosomal subunits
C7M35_00525	COG2176	DNA-directed DNA polymerase activity
C7M35_00526	COG0442	prolyl-tRNA aminoacylation
C7M35_00527	COG0750	zinc metalloprotease
C7M35_00528	COG4589	Belongs to the CDS family
C7M35_00529	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M35_00530	COG0233	cytoplasmic translational termination
C7M35_00531	COG0528	UMP kinase activity
C7M35_00532	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M35_00533	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M35_00535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M35_00536	COG2827	Endonuclease containing a URI domain
C7M35_00537	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M35_00538	COG0204	Acyl-transferase
C7M35_00539	COG3763	UPF0154 protein
C7M35_00540	COG4224	UPF0291 protein
C7M35_00541	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M35_00543	COG3425	synthase
C7M35_00546	COG0463	Glycosyl transferase, family 2
C7M35_00559	COG0393	Putative heavy-metal-binding
C7M35_00562	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M35_00563	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M35_00563	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M35_00564	COG5416	Lipopolysaccharide assembly protein A domain
C7M35_00565	COG0300	oxidoreductase activity
C7M35_00566	COG1234	tRNA 3'-trailer cleavage
C7M35_00568	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M35_00569	COG1349	DNA-binding transcription factor activity
C7M35_00570	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M35_00571	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M35_00571	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M35_00571	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M35_00572	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M35_00577	COG0297	glycogen (starch) synthase activity
C7M35_00578	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M35_00579	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M35_00581	COG0489	protein tyrosine kinase activity
C7M35_00583	COG0322	excinuclease ABC activity
C7M35_00584	COG1126	abc transporter atp-binding protein
C7M35_00585	COG0765	amino acid transport
C7M35_00589	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M35_00590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M35_00591	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M35_00592	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M35_00597	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M35_00598	COG0268	Binds directly to 16S ribosomal RNA
C7M35_00600	COG1466	dna polymerase III delta subunit
C7M35_00601	COG0658	competence protein
C7M35_00601	COG2333	competence protein COMEC
C7M35_00602	COG2131	deaminase
C7M35_00603	COG1596	polysaccharide export
C7M35_00603	COG1555	photosystem II stabilization
C7M35_00604	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M35_00605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M35_00606	COG0742	ribosomal rna small subunit methyltransferase
C7M35_00607	COG4471	UPF0298 protein
C7M35_00608	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M35_00609	COG0772	Belongs to the SEDS family
C7M35_00614	COG1217	gtp-binding protein TYPA
C7M35_00615	COG0483	inositol monophosphate 1-phosphatase activity
C7M35_00616	COG4476	Belongs to the UPF0223 family
C7M35_00617	COG0039	L-malate dehydrogenase activity
C7M35_00622	COG0242	peptide deformylase activity
C7M35_00624	COG5503	Protein of unknown function (DUF1447)
C7M35_00625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M35_00626	COG1597	lipid kinase activity
C7M35_00628	COG1388	LysM domain
C7M35_00628	COG3584	3D domain protein
C7M35_00630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M35_00631	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M35_00638	COG0569	domain protein
C7M35_00639	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M35_00640	COG0482	sulfurtransferase activity
C7M35_00642	COG1104	cysteine desulfurase activity
C7M35_00643	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M35_00645	COG0494	nUDIX hydrolase
C7M35_00646	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M35_00647	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M35_00648	COG3599	regulation of cell shape
C7M35_00650	COG0762	integral membrane protein
C7M35_00651	COG1799	cell septum assembly
C7M35_00654	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M35_00655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M35_00656	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M35_00657	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M35_00658	COG0768	penicillin binding
C7M35_00660	COG0275	rRNA processing
C7M35_00661	COG2001	Belongs to the MraZ family
C7M35_00664	COG1674	ftsk spoiiie
C7M35_00665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M35_00667	COG1114	Component of the transport system for branched-chain amino acids
C7M35_00670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M35_00671	COG0628	permease
C7M35_00673	COG2706	6-phosphogluconolactonase activity
C7M35_00674	COG3142	Participates in the control of copper homeostasis
C7M35_00675	COG0564	pseudouridine synthase activity
C7M35_00676	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M35_00677	COG2357	RelA SpoT domain protein
C7M35_00679	COG1164	Oligoendopeptidase f
C7M35_00681	COG4862	establishment of competence for transformation
C7M35_00682	COG1393	Belongs to the ArsC family
C7M35_00683	COG1234	tRNA 3'-trailer cleavage
C7M35_00711	COG1098	S1 RNA binding domain
C7M35_00713	COG0586	Pfam SNARE associated Golgi protein
C7M35_00715	COG0647	UMP catabolic process
C7M35_00716	COG4470	Protein conserved in bacteria
C7M35_00717	COG0737	Belongs to the 5'-nucleotidase family
C7M35_00719	COG1113	amino acid transport
C7M35_00720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M35_00721	COG0827	DNA restriction-modification system
C7M35_00728	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M35_00730	COG0217	transcriptional regulatory protein
C7M35_00733	COG1609	Transcriptional regulator
C7M35_00734	COG0006	proline dipeptidase activity
C7M35_00735	COG0789	Transcriptional regulator
C7M35_00738	COG0668	transmembrane transport
C7M35_00739	COG1473	amidohydrolase
C7M35_00740	COG2171	N-acyltransferase activity
C7M35_00741	COG0517	IMP dehydrogenase activity
C7M35_00743	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M35_00744	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M35_00745	COG1719	4-vinyl reductase, 4VR
C7M35_00746	COG3118	belongs to the thioredoxin family
C7M35_00747	COG1193	negative regulation of DNA recombination
C7M35_00749	COG3906	Belongs to the UPF0473 family
C7M35_00750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M35_00751	COG4472	Bacterial protein of unknown function (DUF965)
C7M35_00752	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M35_00753	COG0513	Belongs to the DEAD box helicase family
C7M35_00754	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M35_00755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M35_00756	COG1862	Preprotein translocase
C7M35_00757	COG0343	queuine tRNA-ribosyltransferase activity
C7M35_00758	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M35_00759	COG2255	four-way junction helicase activity
C7M35_00760	COG0632	four-way junction helicase activity
C7M35_00764	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M35_00765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M35_00766	COG1692	metallophosphoesterase
C7M35_00767	COG1418	mRNA catabolic process
C7M35_00768	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M35_00769	COG1546	Belongs to the CinA family
C7M35_00769	COG1058	Belongs to the CinA family
C7M35_00770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M35_00771	COG1426	Protein conserved in bacteria
C7M35_00772	COG0612	Peptidase, M16
C7M35_00773	COG0612	Peptidase, M16
C7M35_00774	COG0527	aspartate kinase activity
C7M35_00775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M35_00776	COG1126	abc transporter atp-binding protein
C7M35_00777	COG0765	amino acid transport
C7M35_00778	COG2894	cell division
C7M35_00779	COG0850	regulation of cytokinetic process
C7M35_00781	COG1792	Involved in formation and maintenance of cell shape
C7M35_00782	COG1077	Cell shape determining protein MreB Mrl
C7M35_00783	COG2003	Belongs to the UPF0758 family
C7M35_00784	COG0285	dihydrofolate synthase activity
C7M35_00785	COG0525	valine-tRNA ligase activity
C7M35_00787	COG2918	glutathione biosynthetic process
C7M35_00787	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M35_00788	COG0301	tRNA thio-modification
C7M35_00789	COG1104	cysteine desulfurase activity
C7M35_00791	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M35_00792	COG1956	GAF domain-containing protein
C7M35_00793	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M35_00794	COG4493	Belongs to the UPF0637 family
C7M35_00797	COG0640	Transcriptional regulator
C7M35_00798	COG0366	Alpha amylase catalytic
C7M35_00800	COG3716	PTS system mannose fructose sorbose family IID component
C7M35_00801	COG3715	PTS system
C7M35_00802	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_00803	COG1609	Transcriptional regulator
C7M35_00804	COG0189	ligase activity
C7M35_00804	COG2918	glutathione biosynthetic process
C7M35_00805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M35_00807	COG0589	response to stress
C7M35_00811	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M35_00815	COG1464	Belongs to the NlpA lipoprotein family
C7M35_00816	COG2011	ABC-type metal ion transport system permease component
C7M35_00817	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M35_00818	COG0509	glycine decarboxylation via glycine cleavage system
C7M35_00819	COG0772	Belongs to the SEDS family
C7M35_00821	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M35_00822	COG1077	Cell shape determining protein MreB Mrl
C7M35_00824	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M35_00825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M35_00826	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M35_00827	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M35_00828	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M35_00829	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M35_00830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M35_00831	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M35_00832	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M35_00833	COG2233	PERMEase
C7M35_00834	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M35_00835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M35_00836	COG0009	L-threonylcarbamoyladenylate synthase
C7M35_00837	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M35_00838	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M35_00839	COG1435	thymidine kinase activity
C7M35_00840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M35_00841	COG3442	glutamine amidotransferase
C7M35_00842	COG1482	cell wall glycoprotein biosynthetic process
C7M35_00843	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M35_00845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M35_00848	COG1132	(ABC) transporter
C7M35_00851	COG0726	polysaccharide deacetylase
C7M35_00879	COG5484	DNA packaging
C7M35_00879	COG3728	DNA packaging
C7M35_00904	COG1396	sequence-specific DNA binding
C7M35_00928	COG4886	Leucine-rich repeat (LRR) protein
C7M35_00928	COG4932	domain protein
C7M35_00938	COG1132	(ABC) transporter
C7M35_00940	COG0577	efflux transmembrane transporter activity
C7M35_00940	COG1136	(ABC) transporter
C7M35_00942	COG0166	Belongs to the GPI family
C7M35_00943	COG4975	Glucose uptake
C7M35_00944	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M35_00945	COG5002	protein histidine kinase activity
C7M35_00945	COG3850	Histidine kinase
C7M35_00946	COG0745	RESPONSE REGULATOR receiver
C7M35_00947	COG2848	UPF0210 protein
C7M35_00948	COG3830	Belongs to the UPF0237 family
C7M35_00953	COG0477	Major facilitator Superfamily
C7M35_00958	COG0791	NLP P60 protein
C7M35_00959	COG1522	sequence-specific DNA binding
C7M35_00963	COG0488	(ABC) transporter
C7M35_00967	COG2190	(PTS) system
C7M35_00967	COG1263	PTS System
C7M35_00967	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_00968	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M35_00969	COG1307	EDD domain protein, DegV family
C7M35_00971	COG2873	o-acetylhomoserine
C7M35_00972	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M35_00974	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7M35_00976	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_00977	COG2084	Dehydrogenase
C7M35_00978	COG0861	Integral membrane protein TerC family
C7M35_00979	COG0110	maltose O-acetyltransferase activity
C7M35_00980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7M35_00981	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M35_00982	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M35_00983	COG0107	imidazoleglycerol-phosphate synthase activity
C7M35_00984	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M35_00985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M35_00986	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M35_00987	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M35_00988	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M35_00989	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M35_00990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M35_00995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M35_00998	COG3548	integral membrane protein
C7M35_01002	COG1368	sulfuric ester hydrolase activity
C7M35_01003	COG0584	glycerophosphoryl diester phosphodiesterase
C7M35_01005	COG0492	ferredoxin-NADP+ reductase activity
C7M35_01007	COG4932	domain protein
C7M35_01008	COG2326	polyphosphate kinase activity
C7M35_01009	COG0778	Nitroreductase
C7M35_01011	COG0328	RNA-DNA hybrid ribonuclease activity
C7M35_01012	COG4975	Glucose uptake
C7M35_01013	COG1940	carbohydrate kinase activity
C7M35_01015	COG1349	DNA-binding transcription factor activity
C7M35_01016	COG1882	Formate acetyltransferase
C7M35_01020	COG1609	Transcriptional regulator
C7M35_01021	COG1737	Transcriptional regulator
C7M35_01022	COG0673	inositol 2-dehydrogenase activity
C7M35_01023	COG0673	inositol 2-dehydrogenase activity
C7M35_01024	COG0025	NhaP-type Na H and K H
C7M35_01025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M35_01026	COG1335	isochorismatase
C7M35_01028	COG1131	(ABC) transporter
C7M35_01029	COG1725	Transcriptional regulator
C7M35_01037	COG0028	Belongs to the TPP enzyme family
C7M35_01039	COG1073	alpha beta
C7M35_01040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M35_01041	COG0626	cystathionine gamma-synthase activity
C7M35_01047	COG0095	Lipoate-protein ligase
C7M35_01048	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M35_01049	COG0589	response to stress
C7M35_01050	COG0564	pseudouridine synthase activity
C7M35_01053	COG4640	response to antibiotic
C7M35_01054	COG1396	sequence-specific DNA binding
C7M35_01057	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7M35_01059	COG2188	Transcriptional regulator
C7M35_01060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M35_01062	COG1418	mRNA catabolic process
C7M35_01068	COG1253	flavin adenine dinucleotide binding
C7M35_01069	COG1780	Probably involved in ribonucleotide reductase function
C7M35_01070	COG0025	NhaP-type Na H and K H
C7M35_01071	COG2814	Major facilitator Superfamily
C7M35_01072	COG0789	Transcriptional regulator
C7M35_01073	COG0604	alcohol dehydrogenase
C7M35_01075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M35_01076	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M35_01077	COG0436	Aminotransferase
C7M35_01078	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M35_01081	COG0583	DNA-binding transcription factor activity
C7M35_01082	COG0702	epimerase
C7M35_01084	COG1074	ATP-dependent DNA helicase activity
C7M35_01085	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M35_01087	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M35_01088	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M35_01089	COG0167	dihydroorotate dehydrogenase activity
C7M35_01090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M35_01091	COG0505	Belongs to the CarA family
C7M35_01092	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M35_01093	COG0540	Belongs to the ATCase OTCase family
C7M35_01094	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M35_01095	COG2508	Transcriptional regulator
C7M35_01096	COG2233	PERMEase
C7M35_01097	COG2252	PERMEase
C7M35_01101	COG1215	transferase activity, transferring glycosyl groups
C7M35_01103	COG0151	Belongs to the GarS family
C7M35_01104	COG0138	bifunctional purine biosynthesis protein purh
C7M35_01105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M35_01106	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M35_01108	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M35_01109	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M35_01110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M35_01111	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M35_01112	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M35_01115	COG0431	NADPH-dependent FMN reductase
C7M35_01115	COG3976	FMN-binding domain protein
C7M35_01115	COG1053	succinate dehydrogenase
C7M35_01116	COG0431	NADPH-dependent FMN reductase
C7M35_01116	COG1053	succinate dehydrogenase
C7M35_01116	COG3976	FMN-binding domain protein
C7M35_01117	COG0095	Lipoate-protein ligase
C7M35_01118	COG2365	Tyrosine phosphatase family
C7M35_01122	COG1136	(ABC) transporter
C7M35_01125	COG1725	Transcriptional regulator
C7M35_01126	COG1131	(ABC) transporter
C7M35_01128	COG0589	response to stress
C7M35_01130	COG2246	polysaccharide biosynthetic process
C7M35_01134	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M35_01139	COG0366	Alpha amylase catalytic
C7M35_01141	COG0561	phosphatase activity
C7M35_01143	COG0110	maltose O-acetyltransferase activity
C7M35_01144	COG0494	nUDIX hydrolase
C7M35_01151	COG1827	regulation of RNA biosynthetic process
C7M35_01152	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M35_01153	COG1309	transcriptional regulator
C7M35_01155	COG1131	(ABC) transporter
C7M35_01156	COG3048	D-serine ammonia-lyase activity
C7M35_01157	COG2723	6-phospho-beta-galactosidase activity
C7M35_01158	COG2723	6-phospho-beta-galactosidase activity
C7M35_01159	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M35_01160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_01161	COG2188	Transcriptional regulator
C7M35_01162	COG1216	Glycosyl transferase, family 2
C7M35_01165	COG0561	phosphatase activity
C7M35_01166	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M35_01171	COG0716	FMN binding
C7M35_01175	COG0710	3-dehydroquinate dehydratase activity
C7M35_01176	COG0531	amino acid
C7M35_01185	COG4720	Psort location CytoplasmicMembrane, score
C7M35_01186	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M35_01189	COG4990	cell redox homeostasis
C7M35_01191	COG1811	Na channel or pump
C7M35_01192	COG4978	Transcriptional regulator
C7M35_01192	COG0789	Transcriptional regulator
C7M35_01196	COG0577	efflux transmembrane transporter activity
C7M35_01197	COG1136	(ABC) transporter
C7M35_01205	COG2814	Major facilitator Superfamily
C7M35_01207	COG2814	Major facilitator Superfamily
C7M35_01209	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M35_01210	COG2855	membrane
C7M35_01211	COG0583	DNA-binding transcription factor activity
C7M35_01213	COG0438	transferase activity, transferring glycosyl groups
C7M35_01216	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M35_01217	COG4152	abc transporter atp-binding protein
C7M35_01219	COG4221	oxidoreductase activity
C7M35_01222	COG0789	Transcriptional regulator
C7M35_01227	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M35_01231	COG0456	acetyltransferase
C7M35_01236	COG0583	DNA-binding transcription factor activity
C7M35_01238	COG1063	alcohol dehydrogenase
C7M35_01239	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01244	COG4975	Glucose uptake
C7M35_01246	COG0656	L-ascorbic acid biosynthetic process
C7M35_01247	COG0583	DNA-binding transcription factor activity
C7M35_01251	COG4221	oxidoreductase activity
C7M35_01252	COG0656	L-ascorbic acid biosynthetic process
C7M35_01256	COG0589	response to stress
C7M35_01257	COG0110	maltose O-acetyltransferase activity
C7M35_01258	COG1011	Hydrolase
C7M35_01261	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M35_01263	COG0667	Aldo Keto reductase
C7M35_01265	COG1132	(ABC) transporter
C7M35_01266	COG1132	(ABC) transporter
C7M35_01267	COG2814	Major facilitator Superfamily
C7M35_01269	COG1511	domain protein
C7M35_01269	COG1511	domain protein
C7M35_01271	COG0640	Transcriptional regulator
C7M35_01277	COG0488	(ABC) transporter
C7M35_01278	COG0561	phosphatase activity
C7M35_01280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M35_01283	COG2267	carboxylic ester hydrolase activity
C7M35_01284	COG0531	amino acid
C7M35_01285	COG2270	Major facilitator Superfamily
C7M35_01293	COG2200	EAL domain
C7M35_01295	COG1328	CTP reductase activity
C7M35_01297	COG0242	peptide deformylase activity
C7M35_01299	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M35_01302	COG0583	DNA-binding transcription factor activity
C7M35_01304	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M35_01313	COG0697	spore germination
C7M35_01318	COG1940	carbohydrate kinase activity
C7M35_01319	COG1132	(ABC) transporter
C7M35_01321	COG0778	Nitroreductase
C7M35_01322	COG1263	PTS System
C7M35_01322	COG2190	(PTS) system
C7M35_01322	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_01323	COG1116	anion transmembrane transporter activity
C7M35_01324	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7M35_01330	COG3620	sequence-specific DNA binding
C7M35_01330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M35_01330	COG0617	tRNA 3'-terminal CCA addition
C7M35_01331	COG0410	ABC transporter
C7M35_01334	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7M35_01339	COG5549	protein import
C7M35_01339	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M35_01340	COG2246	polysaccharide biosynthetic process
C7M35_01342	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M35_01346	COG0640	Transcriptional regulator
C7M35_01348	COG1136	(ABC) transporter
C7M35_01348	COG0577	efflux transmembrane transporter activity
C7M35_01355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_01356	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_01357	COG2723	6-phospho-beta-galactosidase activity
C7M35_01359	COG0789	Transcriptional regulator
C7M35_01360	COG0741	lytic transglycosylase activity
C7M35_01364	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M35_01369	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M35_01372	COG4221	oxidoreductase activity
C7M35_01378	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01381	COG1132	(ABC) transporter
C7M35_01382	COG1132	(ABC) transporter
C7M35_01384	COG1473	amidohydrolase
C7M35_01385	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01389	COG0531	amino acid
C7M35_01393	COG2217	Heavy metal translocating P-type atpase
C7M35_01404	COG1063	alcohol dehydrogenase
C7M35_01412	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M35_01415	COG1733	regulation of RNA biosynthetic process
C7M35_01416	COG2814	Major facilitator Superfamily
C7M35_01418	COG0367	asparagine synthase
C7M35_01419	COG3279	Response regulator of the LytR AlgR family
C7M35_01421	COG1309	transcriptional regulator
C7M35_01423	COG1012	belongs to the aldehyde dehydrogenase family
C7M35_01426	COG1733	regulation of RNA biosynthetic process
C7M35_01427	COG0300	oxidoreductase activity
C7M35_01431	COG4989	oxidoreductase activity
C7M35_01432	COG0477	Major facilitator Superfamily
C7M35_01434	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M35_01435	COG1120	ATPase activity
C7M35_01436	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M35_01437	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M35_01438	COG1309	transcriptional regulator
C7M35_01440	COG0640	Transcriptional regulator
C7M35_01441	COG2814	Major facilitator Superfamily
C7M35_01442	COG4221	oxidoreductase activity
C7M35_01443	COG0110	maltose O-acetyltransferase activity
C7M35_01444	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01452	COG0481	GTPase activity
C7M35_01454	COG2816	NAD+ diphosphatase activity
C7M35_01456	COG3976	FMN-binding domain protein
C7M35_01456	COG1053	succinate dehydrogenase
C7M35_01456	COG0431	NADPH-dependent FMN reductase
C7M35_01459	COG0783	Belongs to the Dps family
C7M35_01461	COG2723	6-phospho-beta-galactosidase activity
C7M35_01462	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_01466	COG0789	Transcriptional regulator
C7M35_01470	COG0693	protein deglycase activity
C7M35_01473	COG0577	efflux transmembrane transporter activity
C7M35_01473	COG1136	(ABC) transporter
C7M35_01475	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M35_01476	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M35_01477	COG1376	ErfK ybiS ycfS ynhG family protein
C7M35_01478	COG0656	L-ascorbic acid biosynthetic process
C7M35_01481	COG0477	Major facilitator Superfamily
C7M35_01491	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M35_01493	COG3414	Phosphotransferase system galactitol-specific IIB component
C7M35_01494	COG3775	system Galactitol-specific IIC component
C7M35_01496	COG1349	DNA-binding transcription factor activity
C7M35_01497	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01498	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M35_01499	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M35_01500	COG3775	system Galactitol-specific IIC component
C7M35_01501	COG3414	Phosphotransferase system galactitol-specific IIB component
C7M35_01506	COG2226	methyltransferase
C7M35_01507	COG0588	phosphoglycerate mutase activity
C7M35_01508	COG0628	permease
C7M35_01509	COG1846	Transcriptional regulator
C7M35_01509	COG1940	carbohydrate kinase activity
C7M35_01511	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7M35_01513	COG2815	serine threonine protein kinase
C7M35_01513	COG0515	serine threonine protein kinase
C7M35_01521	COG1247	-acetyltransferase
C7M35_01522	COG1686	Belongs to the peptidase S11 family
C7M35_01526	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M35_01527	COG0516	GMP reductase activity
C7M35_01527	COG0517	IMP dehydrogenase activity
C7M35_01529	COG0012	GTP binding
C7M35_01530	COG4481	Protein conserved in bacteria
C7M35_01531	COG1475	DNA binding
C7M35_01532	COG1192	Involved in chromosome partitioning
C7M35_01534	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M35_01535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M35_01538	COG0583	DNA-binding transcription factor activity
C7M35_01539	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M35_01540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M35_01541	COG0765	amino acid transport
C7M35_01542	COG1126	abc transporter atp-binding protein
C7M35_01543	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M35_01548	COG1263	PTS System
C7M35_01548	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_01548	COG2190	(PTS) system
C7M35_01549	COG0366	Alpha amylase catalytic
C7M35_01550	COG1609	Transcriptional regulator
C7M35_01552	COG0390	transport system, permease component
C7M35_01553	COG4619	ABC transporter
C7M35_01554	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M35_01557	COG0561	phosphatase activity
C7M35_01560	COG2190	(PTS) system
C7M35_01560	COG1263	PTS System
C7M35_01560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_01566	COG0735	belongs to the Fur family
C7M35_01571	COG1380	Effector of murein hydrolase LrgA
C7M35_01573	COG1307	EDD domain protein, DegV family
C7M35_01575	COG2738	Putative neutral zinc metallopeptidase
C7M35_01576	COG1233	COG1233 Phytoene dehydrogenase and related
C7M35_01577	COG1562	ergosterol biosynthetic process
C7M35_01579	COG1929	Belongs to the glycerate kinase type-1 family
C7M35_01582	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M35_01583	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7M35_01584	COG0516	GMP reductase activity
C7M35_01585	COG2365	Tyrosine phosphatase family
C7M35_01586	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M35_01589	COG0531	amino acid
C7M35_01591	COG3158	transport of potassium into the cell
C7M35_01592	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M35_01593	COG0628	permease
C7M35_01595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M35_01598	COG1272	protein, Hemolysin III
C7M35_01599	COG0640	Transcriptional regulator
C7M35_01606	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M35_01608	COG0302	gtp cyclohydrolase
C7M35_01609	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M35_01612	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M35_01613	COG2814	Major facilitator Superfamily
C7M35_01620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M35_01621	COG1882	Formate acetyltransferase
C7M35_01622	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7M35_01623	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M35_01624	COG4989	oxidoreductase activity
C7M35_01630	COG2217	Heavy metal translocating P-type atpase
C7M35_01632	COG2315	Protein conserved in bacteria
C7M35_01635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M35_01636	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M35_01638	COG1757	Na H antiporter
C7M35_01639	COG1113	amino acid transport
C7M35_01641	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M35_01644	COG1393	Belongs to the ArsC family
C7M35_01645	COG3189	MarR family transcriptional regulator
C7M35_01647	COG1194	a g-specific adenine glycosylase
C7M35_01650	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M35_01655	COG0697	spore germination
C7M35_01658	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M35_01663	COG0477	Major facilitator Superfamily
C7M35_01673	COG0737	Belongs to the 5'-nucleotidase family
C7M35_01675	COG0656	L-ascorbic acid biosynthetic process
C7M35_01679	COG1968	undecaprenyl-diphosphatase activity
C7M35_01680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7M35_01687	COG2207	Transcriptional regulator
C7M35_01692	COG0076	glutamate decarboxylase activity
C7M35_01699	COG2226	methyltransferase
C7M35_01702	COG2217	Heavy metal translocating P-type atpase
C7M35_01703	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_01704	COG3118	belongs to the thioredoxin family
C7M35_01705	COG1937	Protein conserved in bacteria
C7M35_01709	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M35_01710	COG3590	peptidase
C7M35_01712	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_01722	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_01724	COG1114	Component of the transport system for branched-chain amino acids
C7M35_01726	COG1874	Beta-galactosidase
C7M35_01727	COG1609	Transcriptional regulator
C7M35_01729	COG0477	Major facilitator Superfamily
C7M35_01733	COG2184	nucleotidyltransferase activity
C7M35_01734	COG2944	sequence-specific DNA binding
C7M35_01735	COG1609	Transcriptional regulator
C7M35_01736	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M35_01737	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M35_01738	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M35_01742	COG2190	(PTS) system
C7M35_01742	COG2211	Major facilitator Superfamily
C7M35_01743	COG2017	converts alpha-aldose to the beta-anomer
C7M35_01744	COG1609	Transcriptional regulator
C7M35_01745	COG0667	Aldo Keto reductase
C7M35_01749	COG0710	3-dehydroquinate dehydratase activity
C7M35_01750	COG0738	Major facilitator superfamily
C7M35_01751	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M35_01752	COG0583	DNA-binding transcription factor activity
C7M35_01753	COG0738	Major facilitator superfamily
C7M35_01755	COG2267	carboxylic ester hydrolase activity
C7M35_01756	COG2188	Transcriptional regulator
C7M35_01757	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_01758	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M35_01759	COG2971	BadF BadG BcrA BcrD
C7M35_01761	COG2723	6-phospho-beta-galactosidase activity
C7M35_01764	COG0318	PFAM AMP-dependent synthetase and ligase
C7M35_01765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M35_01767	COG1960	acyl-CoA dehydrogenase activity
C7M35_01770	COG2223	nitrite transmembrane transporter activity
C7M35_01771	COG0583	DNA-binding transcription factor activity
C7M35_01772	COG2723	6-phospho-beta-galactosidase activity
C7M35_01773	COG2190	(PTS) system
C7M35_01773	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_01773	COG1263	PTS System
C7M35_01777	COG2211	Major facilitator Superfamily
C7M35_01780	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M35_01783	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M35_01787	COG3711	transcriptional antiterminator
C7M35_01790	COG1063	alcohol dehydrogenase
C7M35_01791	COG3775	system Galactitol-specific IIC component
C7M35_01792	COG3414	Phosphotransferase system galactitol-specific IIB component
C7M35_01794	COG1349	DNA-binding transcription factor activity
C7M35_01795	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7M35_01797	COG0110	maltose O-acetyltransferase activity
C7M35_01798	COG2160	L-arabinose isomerase activity
C7M35_01802	COG1609	Transcriptional regulator
C7M35_01803	COG1737	Transcriptional regulator
C7M35_01807	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M35_01811	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M35_01812	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7M35_01817	COG2261	transglycosylase associated protein
C7M35_01819	COG1393	Belongs to the ArsC family
C7M35_01823	COG4512	PFAM Accessory gene regulator B
C7M35_01826	COG1304	FMN binding
C7M35_01827	COG0028	Belongs to the TPP enzyme family
C7M35_01828	COG1959	2 iron, 2 sulfur cluster binding
C7M35_01829	COG0028	Belongs to the TPP enzyme family
C7M35_01832	COG0235	Class ii aldolase
C7M35_01833	COG4806	L-rhamnose isomerase
C7M35_01834	COG3254	rhamnose metabolic process
C7M35_01835	COG1070	Carbohydrate kinase
C7M35_01836	COG2814	Major facilitator Superfamily
C7M35_01837	COG2207	Transcriptional regulator
C7M35_01838	COG1349	DNA-binding transcription factor activity
C7M35_01841	COG3775	system Galactitol-specific IIC component
C7M35_01844	COG2814	Major facilitator Superfamily
C7M35_01845	COG0673	inositol 2-dehydrogenase activity
C7M35_01846	COG0673	inositol 2-dehydrogenase activity
C7M35_01847	COG1082	Xylose isomerase domain protein TIM barrel
C7M35_01848	COG0673	inositol 2-dehydrogenase activity
C7M35_01849	COG2814	Major facilitator Superfamily
C7M35_01850	COG0673	inositol 2-dehydrogenase activity
C7M35_01851	COG4702	Belongs to the UPF0303 family
C7M35_01852	COG0604	alcohol dehydrogenase
C7M35_01854	COG1957	nucleoside hydrolase
C7M35_01857	COG3732	PTS system glucitol sorbitol-specific
C7M35_01858	COG3730	PTS system glucitol sorbitol-specific
C7M35_01860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M35_01860	COG3711	transcriptional antiterminator
C7M35_01862	COG2723	6-phospho-beta-galactosidase activity
C7M35_01863	COG1940	carbohydrate kinase activity
C7M35_01864	COG0383	alpha-mannosidase activity
C7M35_01866	COG2188	Transcriptional regulator
C7M35_01868	COG3842	ATPase activity
C7M35_01870	COG4753	response regulator
C7M35_01870	COG2207	Transcriptional regulator
C7M35_01871	COG2972	Histidine kinase
C7M35_01873	COG0366	Alpha amylase catalytic
C7M35_01874	COG1653	transport
C7M35_01875	COG0395	ABC-type sugar transport system, permease component
C7M35_01878	COG2207	Transcriptional regulator
C7M35_01878	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M35_01879	COG1132	(ABC) transporter
C7M35_01880	COG1132	(ABC) transporter
C7M35_01881	COG2188	Transcriptional regulator
C7M35_01884	COG3732	PTS system glucitol sorbitol-specific
C7M35_01885	COG3730	PTS system glucitol sorbitol-specific
C7M35_01889	COG4975	Glucose uptake
C7M35_01890	COG1869	D-ribose catabolic process
C7M35_01892	COG1609	Transcriptional regulator
C7M35_01893	COG1012	belongs to the aldehyde dehydrogenase family
C7M35_01893	COG1454	alcohol dehydrogenase
C7M35_01896	COG1695	Transcriptional regulator
C7M35_01897	COG3479	Phenolic acid decarboxylase
C7M35_01900	COG1307	EDD domain protein, DegV family
C7M35_01909	COG0445	tRNA wobble uridine modification
C7M35_01910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M35_01911	COG1847	R3H domain protein
C7M35_01913	COG4166	transmembrane transport
C7M35_01914	COG0706	membrane insertase activity
C7M35_01915	COG0594	ribonuclease P activity
C7M35_01916	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M35_01917	COG0592	DNA-directed DNA polymerase activity
C7M35_01918	COG2501	S4 domain
C7M35_01919	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M35_01920	COG0187	DNA topoisomerase II activity
C7M35_01922	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M35_01923	COG0629	single-stranded DNA binding
C7M35_01924	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M35_01926	COG0359	binds to the 23S rRNA
C7M35_01927	COG0305	Participates in initiation and elongation during chromosome replication
C7M35_01928	COG2814	Major facilitator Superfamily
C7M35_01929	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M35_01930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M35_01932	COG4166	transmembrane transport
C7M35_01934	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M35_01935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M35_01936	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M35_01937	COG0297	glycogen (starch) synthase activity
C7M35_01939	COG0058	SHG alpha-glucan phosphorylase activity
C7M35_01940	COG3103	Sh3 type 3 domain protein
C7M35_01940	COG0366	Alpha amylase catalytic
C7M35_01943	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M35_01944	COG1554	hydrolase, family 65, central catalytic
C7M35_01946	COG1278	Cold shock
C7M35_01961	COG4695	Portal protein
C7M35_01968	COG0745	RESPONSE REGULATOR receiver
C7M35_01969	COG5002	protein histidine kinase activity
C7M35_01971	COG4853	Protein conserved in bacteria
C7M35_01972	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M35_01973	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M35_01974	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M35_01976	COG1012	belongs to the aldehyde dehydrogenase family
C7M35_01977	COG1573	uracil-dna glycosylase
C7M35_01981	COG0431	NADPH-dependent FMN reductase
C7M35_01981	COG1053	succinate dehydrogenase
C7M35_01981	COG3976	FMN-binding domain protein
C7M35_01982	COG0471	metal ion transport
C7M35_01985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M35_01986	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_01988	COG0778	Nitroreductase
C7M35_01989	COG2508	Transcriptional regulator
C7M35_01990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M35_01991	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M35_01993	COG2365	Tyrosine phosphatase family
C7M35_01994	COG2368	4-hydroxyphenylacetate
C7M35_01998	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M35_02005	COG0604	alcohol dehydrogenase
C7M35_02008	COG2267	carboxylic ester hydrolase activity
C7M35_02009	COG3022	response to hydroperoxide
C7M35_02011	COG4166	transmembrane transport
C7M35_02016	COG1122	ATPase activity
C7M35_02017	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M35_02018	COG0310	cobalt ion transport
C7M35_02019	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M35_02020	COG3875	lactate racemase activity
C7M35_02021	COG1691	(AIR) carboxylase
C7M35_02022	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
C7M35_02023	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_02024	COG1606	tRNA processing
C7M35_02026	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M35_02027	COG0351	phosphomethylpyrimidine kinase
C7M35_02028	COG0352	thiamine-phosphate diphosphorylase activity
C7M35_02030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7M35_02033	COG1113	amino acid transport
C7M35_02036	COG2267	carboxylic ester hydrolase activity
C7M35_02037	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
C7M35_02038	COG1518	maintenance of DNA repeat elements
C7M35_02041	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M35_02043	COG1983	PspC domain protein
C7M35_02050	COG2807	transmembrane transport
C7M35_02052	COG0656	L-ascorbic acid biosynthetic process
C7M35_02053	COG0667	Aldo Keto reductase
C7M35_02059	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M35_02060	COG1122	ATPase activity
C7M35_02061	COG4720	Psort location CytoplasmicMembrane, score
C7M35_02062	COG2188	Transcriptional regulator
C7M35_02067	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_02069	COG1028	Short-chain dehydrogenase reductase Sdr
C7M35_02070	COG1131	(ABC) transporter
C7M35_02073	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M35_02074	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M35_02076	COG1309	transcriptional regulator
C7M35_02077	COG2376	Dihydroxyacetone kinase
C7M35_02078	COG2376	Dihydroxyacetone kinase
C7M35_02079	COG1461	Dihydroxyacetone kinase
C7M35_02080	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7M35_02081	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_02082	COG1609	Transcriptional regulator
C7M35_02083	COG1609	Transcriptional regulator
C7M35_02084	COG0366	Alpha amylase catalytic
C7M35_02085	COG2182	Extracellular solute-binding protein
C7M35_02086	COG1175	transmembrane transport
C7M35_02087	COG3833	ABC-type maltose transport systems, permease component
C7M35_02089	COG0366	Alpha amylase catalytic
C7M35_02090	COG3842	ATPase activity
C7M35_02101	COG1757	Na H antiporter
C7M35_02107	COG4166	transmembrane transport
C7M35_02108	COG4166	transmembrane transport
C7M35_02110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M35_02111	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M35_02112	COG0406	alpha-ribazole phosphatase activity
C7M35_02113	COG0667	Aldo Keto reductase
C7M35_02114	COG0667	Aldo Keto reductase
C7M35_02120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M35_02121	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M35_02122	COG0488	(ABC) transporter
C7M35_02125	COG4172	Belongs to the ABC transporter superfamily
C7M35_02127	COG0386	Belongs to the glutathione peroxidase family
C7M35_02129	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M35_02131	COG0363	glucosamine-6-phosphate deaminase activity
C7M35_02134	COG2213	PTS system mannitol-specific
C7M35_02136	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M35_02137	COG0246	Mannitol dehydrogenase
C7M35_02139	COG3118	belongs to the thioredoxin family
C7M35_02145	COG0431	NADPH-dependent FMN reductase
C7M35_02146	COG1045	serine acetyltransferase
C7M35_02147	COG0626	cystathionine gamma-synthase activity
C7M35_02148	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M35_02153	COG2188	Transcriptional regulator
C7M35_02154	COG0366	Alpha amylase catalytic
C7M35_02155	COG2190	(PTS) system
C7M35_02155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02155	COG1263	PTS System
C7M35_02156	COG2190	(PTS) system
C7M35_02156	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02156	COG1263	PTS System
C7M35_02158	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M35_02159	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M35_02160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M35_02162	COG0163	prenyltransferase activity
C7M35_02164	COG1959	2 iron, 2 sulfur cluster binding
C7M35_02165	COG1309	transcriptional regulator
C7M35_02166	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M35_02170	COG2814	Major facilitator Superfamily
C7M35_02173	COG5002	protein histidine kinase activity
C7M35_02174	COG0745	RESPONSE REGULATOR receiver
C7M35_02176	COG1737	Transcriptional regulator
C7M35_02177	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02180	COG1316	TRANSCRIPTIONal
C7M35_02181	COG0277	FAD linked oxidase domain protein
C7M35_02183	COG2357	RelA SpoT domain protein
C7M35_02185	COG2409	Drug exporters of the RND superfamily
C7M35_02185	COG1033	growth of symbiont in host cell
C7M35_02186	COG2818	Glycosylase
C7M35_02188	COG0577	efflux transmembrane transporter activity
C7M35_02189	COG1136	(ABC) transporter
C7M35_02192	COG0741	lytic transglycosylase activity
C7M35_02193	COG1388	LysM domain
C7M35_02193	COG3942	CHAP domain
C7M35_02199	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M35_02201	COG1846	Transcriptional regulator
C7M35_02202	COG1252	NADH dehydrogenase
C7M35_02210	COG3842	ATPase activity
C7M35_02216	COG1725	Transcriptional regulator
C7M35_02217	COG1131	(ABC) transporter
C7M35_02219	COG1454	alcohol dehydrogenase
C7M35_02219	COG1012	belongs to the aldehyde dehydrogenase family
C7M35_02227	COG1268	BioY protein
C7M35_02230	COG0436	Aminotransferase
C7M35_02232	COG1682	transport, permease protein
C7M35_02233	COG1134	teichoic acid transport
C7M35_02236	COG2814	Major facilitator Superfamily
C7M35_02237	COG0004	ammonium transporteR
C7M35_02241	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7M35_02243	COG3759	membrane
C7M35_02244	COG1881	PFAM PEBP family protein
C7M35_02250	COG0300	oxidoreductase activity
C7M35_02254	COG1125	glycine betaine transport
C7M35_02256	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M35_02258	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_02268	COG0110	maltose O-acetyltransferase activity
C7M35_02270	COG0561	phosphatase activity
C7M35_02272	COG0561	phosphatase activity
C7M35_02273	COG1114	Component of the transport system for branched-chain amino acids
C7M35_02278	COG0475	glutathione-regulated potassium exporter activity
C7M35_02287	COG3290	protein histidine kinase activity
C7M35_02292	COG2274	protein secretion by the type I secretion system
C7M35_02299	COG3973	AAA domain
C7M35_02300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M35_02301	COG0180	Tryptophanyl-tRNA synthetase
C7M35_02302	COG2188	Transcriptional regulator
C7M35_02303	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02306	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02307	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02308	COG2723	6-phospho-beta-galactosidase activity
C7M35_02309	COG1940	carbohydrate kinase activity
C7M35_02311	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M35_02314	COG0248	Ppx GppA phosphatase
C7M35_02317	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M35_02318	COG1801	Protein of unknown function DUF72
C7M35_02320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M35_02320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M35_02321	COG2814	Major facilitator Superfamily
C7M35_02322	COG0084	hydrolase, TatD family'
C7M35_02323	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M35_02324	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M35_02325	COG4466	Protein conserved in bacteria
C7M35_02326	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M35_02327	COG1073	alpha beta
C7M35_02328	COG1121	(ABC) transporter
C7M35_02329	COG1321	iron dependent repressor
C7M35_02329	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M35_02333	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M35_02334	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M35_02336	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M35_02340	COG1078	dGTPase activity
C7M35_02341	COG0095	Lipoate-protein ligase
C7M35_02343	COG3343	RNA polymerase activity
C7M35_02344	COG0504	CTP synthase activity
C7M35_02345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M35_02346	COG0814	amino acid
C7M35_02347	COG1760	l-serine dehydratase
C7M35_02348	COG1760	l-serine dehydratase
C7M35_02351	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M35_02352	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M35_02353	COG0254	rRNA binding
C7M35_02355	COG3764	Sortase (surface protein transpeptidase)
C7M35_02356	COG1704	LemA family
C7M35_02357	COG0501	Belongs to the peptidase M48B family
C7M35_02359	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M35_02361	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M35_02362	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M35_02363	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M35_02364	COG3158	transport of potassium into the cell
C7M35_02365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M35_02366	COG0505	Belongs to the CarA family
C7M35_02367	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M35_02368	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M35_02369	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7M35_02370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M35_02371	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M35_02374	COG2267	carboxylic ester hydrolase activity
C7M35_02377	COG0039	L-malate dehydrogenase activity
C7M35_02378	COG0193	aminoacyl-tRNA hydrolase activity
C7M35_02379	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M35_02380	COG2244	polysaccharide biosynthetic process
C7M35_02381	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M35_02384	COG1098	S1 RNA binding domain
C7M35_02385	COG0037	tRNA processing
C7M35_02388	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M35_02389	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M35_02390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M35_02398	COG3104	oligopeptide transport
C7M35_02408	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M35_02410	COG2188	Transcriptional regulator
C7M35_02412	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M35_02413	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M35_02416	COG2183	response to ionizing radiation
C7M35_02417	COG3091	SprT-like family
C7M35_02418	COG0460	homoserine dehydrogenase
C7M35_02419	COG0083	homoserine kinase activity
C7M35_02423	COG3715	PTS system
C7M35_02424	COG3716	PTS system mannose fructose sorbose family IID component
C7M35_02426	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M35_02426	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M35_02427	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M35_02427	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02428	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02428	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M35_02429	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M35_02431	COG0439	Biotin carboxylase
C7M35_02433	COG0825	malonyl-CoA metabolic process
C7M35_02434	COG1316	TRANSCRIPTIONal
C7M35_02436	COG0697	spore germination
C7M35_02437	COG0588	phosphoglycerate mutase activity
C7M35_02438	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M35_02438	COG5549	protein import
C7M35_02440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7M35_02442	COG0756	dUTP diphosphatase activity
C7M35_02444	COG4956	integral membrane protein (PIN domain superfamily)
C7M35_02445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M35_02446	COG0215	cysteine-tRNA ligase activity
C7M35_02447	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M35_02448	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M35_02451	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M35_02453	COG0250	Participates in transcription elongation, termination and antitermination
C7M35_02455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M35_02456	COG0081	regulation of translation
C7M35_02457	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M35_02458	COG0222	ribosome binding
C7M35_02463	COG1611	Belongs to the LOG family
C7M35_02465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M35_02466	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M35_02467	COG2813	Specifically methylates the guanine in position
C7M35_02469	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M35_02470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M35_02471	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M35_02473	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M35_02474	COG3870	Protein conserved in bacteria
C7M35_02475	COG0470	DNA polymerase III
C7M35_02476	COG4467	Involved in initiation control of chromosome replication
C7M35_02479	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M35_02480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M35_02481	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M35_02482	COG3639	organic phosphonate transmembrane transporter activity
C7M35_02484	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C7M35_02486	COG1214	PFAM Peptidase M22, glycoprotease
C7M35_02487	COG0456	acetyltransferase
C7M35_02488	COG0456	acetyltransferase
C7M35_02489	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M35_02490	COG0488	(ABC) transporter
C7M35_02491	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M35_02494	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M35_02495	COG0459	protein refolding
C7M35_02496	COG0531	amino acid
C7M35_02497	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M35_02498	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M35_02499	COG1739	Uncharacterized protein family UPF0029
C7M35_02500	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M35_02503	COG0653	protein targeting
C7M35_02504	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7M35_02506	COG0745	RESPONSE REGULATOR receiver
C7M35_02507	COG5002	protein histidine kinase activity
C7M35_02509	COG0573	inorganic phosphate transmembrane transporter activity
C7M35_02510	COG0581	inorganic phosphate transmembrane transporter activity
C7M35_02511	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M35_02512	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M35_02513	COG0704	Plays a role in the regulation of phosphate uptake
C7M35_02514	COG1983	PspC domain protein
C7M35_02515	COG1950	PFAM Membrane protein of
C7M35_02516	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M35_02517	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M35_02518	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M35_02519	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M35_02521	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_02522	COG0492	ferredoxin-NADP+ reductase activity
C7M35_02523	COG2323	membrane
C7M35_02525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M35_02527	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7M35_02529	COG2814	Major facilitator Superfamily
C7M35_02531	COG0556	nucleotide-excision repair
C7M35_02532	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M35_02533	COG1854	S-ribosylhomocysteine lyase activity
C7M35_02534	COG0137	argininosuccinate synthase activity
C7M35_02535	COG0165	Argininosuccinate lyase
C7M35_02537	COG1660	Displays ATPase and GTPase activities
C7M35_02539	COG1481	regulation of sporulation
C7M35_02541	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M35_02542	COG0740	serine-type endopeptidase activity
C7M35_02544	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M35_02545	COG2390	Transcriptional regulator
C7M35_02547	COG0126	phosphoglycerate kinase activity
C7M35_02548	COG0149	triose-phosphate isomerase activity
C7M35_02549	COG0148	phosphopyruvate hydratase activity
C7M35_02551	COG0038	chloride channel
C7M35_02552	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M35_02554	COG0557	exoribonuclease II activity
C7M35_02555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M35_02557	COG0765	amino acid transport
C7M35_02558	COG1126	abc transporter atp-binding protein
C7M35_02560	COG0561	phosphatase activity
C7M35_02561	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M35_02562	COG0280	phosphate acetyltransferase
C7M35_02563	COG0802	atpase or kinase
C7M35_02566	COG0708	Exodeoxyribonuclease III
C7M35_02568	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M35_02569	COG0025	NhaP-type Na H and K H
C7M35_02574	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M35_02575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M35_02577	COG0561	phosphatase activity
C7M35_02579	COG2017	converts alpha-aldose to the beta-anomer
C7M35_02582	COG0778	Nitroreductase
C7M35_02585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M35_02588	COG1393	Belongs to the ArsC family
C7M35_02591	COG0477	Major facilitator Superfamily
C7M35_02592	COG0248	Ppx GppA phosphatase
C7M35_02593	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7M35_02595	COG3475	LICD family
C7M35_02598	COG2252	PERMEase
C7M35_02599	COG0028	Belongs to the TPP enzyme family
C7M35_02600	COG0196	riboflavin kinase activity
C7M35_02601	COG0028	Belongs to the TPP enzyme family
C7M35_02602	COG2267	carboxylic ester hydrolase activity
C7M35_02604	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M35_02604	COG2755	lipolytic protein G-D-S-L family
C7M35_02605	COG2936	dipeptidyl-peptidase activity
C7M35_02608	COG0531	amino acid
C7M35_02613	COG0194	GDP metabolic process
C7M35_02614	COG0735	belongs to the Fur family
C7M35_02618	COG0546	phosphoglycolate phosphatase activity
C7M35_02619	COG0436	Aminotransferase
C7M35_02620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M35_02624	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M35_02625	COG0765	amino acid transport
C7M35_02626	COG0765	amino acid transport
C7M35_02627	COG2190	(PTS) system
C7M35_02627	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02627	COG1263	PTS System
C7M35_02629	COG1263	PTS System
C7M35_02629	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M35_02630	COG3394	polysaccharide catabolic process
C7M35_02631	COG0531	amino acid
C7M35_02632	COG1846	Transcriptional regulator
C7M35_02638	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M35_02640	COG2076	Multidrug Resistance protein
C7M35_02643	COG0588	phosphoglycerate mutase activity
C7M35_02644	COG0475	glutathione-regulated potassium exporter activity
C7M35_02644	COG0569	domain protein
C7M35_02645	COG0456	acetyltransferase
C7M35_02645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M35_02646	COG0586	Pfam SNARE associated Golgi protein
C7M35_02647	COG3973	AAA domain
C7M35_02648	COG2070	2-Nitropropane dioxygenase
C7M35_02649	COG1072	(Pantothenic acid kinase))
C7M35_02650	COG0519	Catalyzes the synthesis of GMP from XMP
C7M35_02650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M35_02652	COG0464	growth
C7M35_02660	COG1396	sequence-specific DNA binding
C7M35_02661	COG1266	CAAX protease self-immunity
C7M35_02662	COG1733	regulation of RNA biosynthetic process
C7M35_02663	COG2814	Major facilitator Superfamily
C7M35_02666	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M35_02666	COG2755	lipolytic protein G-D-S-L family
C7M35_02667	COG2261	transglycosylase associated protein
C7M35_02670	COG1302	Protein conserved in bacteria
C7M35_02676	COG0308	aminopeptidase N
C7M35_02684	COG0572	uridine kinase
C7M35_02687	COG0583	DNA-binding transcription factor activity
C7M35_02688	COG1053	succinate dehydrogenase
C7M35_02691	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M35_02692	COG0017	Asparaginyl-tRNA synthetase
C7M35_02693	COG2502	aspartate--ammonia ligase
C7M35_02694	COG4690	dipeptidase activity
C7M35_02698	COG0514	ATP-dependent DNA helicase (RecQ)
C7M35_02699	COG0564	pseudouridine synthase activity
C7M35_02700	COG0640	Transcriptional regulator
C7M35_02710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M35_02711	COG0527	aspartate kinase activity
C7M35_02712	COG0367	asparagine synthase
C7M35_02718	COG2814	Major facilitator Superfamily
C7M35_02722	COG1278	Cold shock
C7M35_02723	COG2966	Psort location CytoplasmicMembrane, score
C7M35_02725	COG1316	TRANSCRIPTIONal
C7M35_02729	COG1959	2 iron, 2 sulfur cluster binding
C7M35_02730	COG0028	Belongs to the TPP enzyme family
C7M35_02731	COG0833	amino acid
C7M35_02733	COG1428	Deoxynucleoside kinase
C7M35_02734	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M35_02742	COG4463	regulation of RNA biosynthetic process
C7M35_02743	COG0542	response to heat
C7M35_02745	COG0085	RNA polymerase activity
C7M35_02746	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M35_02747	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M35_02748	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M35_02749	COG0049	tRNA binding
C7M35_02750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M35_02751	COG0051	transcription antitermination factor activity, RNA binding
C7M35_02752	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M35_02753	COG0088	Forms part of the polypeptide exit tunnel
C7M35_02754	COG0089	rRNA binding
C7M35_02755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M35_02756	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M35_02757	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M35_02758	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M35_02759	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M35_02760	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M35_02761	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M35_02762	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M35_02763	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7M35_02764	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M35_02765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M35_02766	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M35_02767	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M35_02768	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7M35_02769	COG1841	ribosomal large subunit assembly
C7M35_02770	COG0200	Binds to the 23S rRNA
C7M35_02772	COG0563	adenylate kinase activity
C7M35_02773	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M35_02774	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M35_02775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M35_02776	COG0202	RNA polymerase activity
C7M35_02777	COG0203	ribosomal protein L17
C7M35_02782	COG4939	FMN-binding domain protein
C7M35_02784	COG1122	ATPase activity
C7M35_02785	COG1122	ATPase activity
C7M35_02787	COG0101	tRNA pseudouridine synthase activity
C7M35_02788	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M35_02789	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M35_02793	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M35_02794	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M35_02795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M35_02796	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M35_02797	COG0471	metal ion transport
C7M35_02798	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M35_02799	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7M35_02801	COG1917	Cupin 2, conserved barrel domain protein
C7M35_02801	COG4977	sequence-specific DNA binding
C7M35_02802	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7M35_02803	COG1121	(ABC) transporter
C7M35_02804	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M35_02805	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M35_02807	COG0039	L-malate dehydrogenase activity
C7M35_02808	COG0471	metal ion transport
C7M35_02812	COG3052	prosthetic group binding
C7M35_02820	COG0114	fumarate hydratase activity
C7M35_02821	COG1053	succinate dehydrogenase
C7M35_02823	COG0583	DNA-binding transcription factor activity
C7M35_02824	COG0583	DNA-binding transcription factor activity
C7M35_02825	COG0281	malic enzyme
C7M35_02827	COG0531	amino acid
C7M35_02828	COG4684	Psort location CytoplasmicMembrane, score
C7M35_02831	COG1271	oxidase subunit
C7M35_02832	COG1294	oxidase, subunit
C7M35_02833	COG4988	ABC transporter
C7M35_02834	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M35_02836	COG0142	geranyltranstransferase activity
C7M35_02839	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M35_02840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M35_02841	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M35_02842	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M35_02844	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M35_02845	COG4851	CamS sex pheromone cAM373 precursor
C7M35_02846	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M35_02847	COG0154	amidase activity
C7M35_02848	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M35_02849	COG1597	lipid kinase activity
C7M35_02850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M35_02853	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02855	COG1737	Transcriptional regulator
C7M35_02858	COG1278	Cold shock
C7M35_02859	COG0673	inositol 2-dehydrogenase activity
C7M35_02860	COG0513	Belongs to the DEAD box helicase family
C7M35_02863	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M35_02868	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M35_02870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M35_02872	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M35_02873	COG0562	UDP-galactopyranose mutase
C7M35_02879	COG1216	Glycosyl transferase, family 2
C7M35_02879	COG1442	glycosyl transferase family 8
C7M35_02883	COG2244	polysaccharide biosynthetic process
C7M35_02890	COG2207	Transcriptional regulator
C7M35_02890	COG1609	Transcriptional regulator
C7M35_02894	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M35_02901	COG2137	regulation of response to DNA damage stimulus
C7M35_02902	COG3557	Belongs to the UPF0374 family
C7M35_02906	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M35_02908	COG0628	permease
C7M35_02909	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M35_02910	COG2610	gluconate transmembrane transporter activity
C7M35_02911	COG1070	Carbohydrate kinase
C7M35_02912	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M35_02913	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M35_02914	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7M35_02920	COG4166	transmembrane transport
C7M35_02921	COG0601	transmembrane transport
C7M35_02922	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M35_02923	COG0444	Belongs to the ABC transporter superfamily
C7M35_02924	COG4608	Belongs to the ABC transporter superfamily
C7M35_02926	COG0582	viral genome integration into host DNA
C7M35_02927	COG0542	response to heat
C7M35_02931	COG0438	transferase activity, transferring glycosyl groups
C7M35_02932	COG0438	transferase activity, transferring glycosyl groups
C7M35_02934	COG1686	Belongs to the peptidase S11 family
C7M35_02935	COG0436	Aminotransferase
C7M35_02936	COG4703	Protein of unknown function (DUF1797)
C7M35_02937	COG1368	sulfuric ester hydrolase activity
C7M35_02954	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M35_02958	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M35_02961	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7M35_02962	COG0833	amino acid
C7M35_02963	COG2040	homocysteine
C7M35_02964	COG0438	transferase activity, transferring glycosyl groups
C7M35_02966	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M35_02967	COG0477	Major facilitator Superfamily
C7M35_02970	COG0438	transferase activity, transferring glycosyl groups
C7M35_02973	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M35_02975	COG0495	leucyl-tRNA aminoacylation
C7M35_02976	COG2244	polysaccharide biosynthetic process
C7M35_02977	COG1187	pseudouridine synthase activity
C7M35_02978	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M35_02979	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M35_02981	COG3842	ATPase activity
C7M35_02982	COG1175	transmembrane transport
C7M35_02983	COG0395	ABC-type sugar transport system, permease component
C7M35_02985	COG0584	glycerophosphoryl diester phosphodiesterase
C7M35_02986	COG1428	Deoxynucleoside kinase
C7M35_02987	COG1970	mechanosensitive ion channel activity
C7M35_02988	COG1511	domain protein
C7M35_02988	COG1511	domain protein
C7M35_02993	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M35_02994	COG0789	Transcriptional regulator
C7M35_02996	COG0697	spore germination
C7M35_02997	COG0561	phosphatase activity
C7M35_03000	COG3279	Response regulator of the LytR AlgR family
C7M35_03004	COG1846	Transcriptional regulator
C7M35_03007	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M35_03015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M35_03015	COG0646	methionine synthase
C7M35_03016	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M35_03018	COG2046	Belongs to the sulfate adenylyltransferase family
C7M35_03019	COG0529	Catalyzes the synthesis of activated sulfate
C7M35_03020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M35_03022	COG3273	potassium ion transport
C7M35_03022	COG0471	metal ion transport
C7M35_03023	COG0534	Mate efflux family protein
C7M35_03027	COG2153	protein acetylation
C7M35_03028	COG0018	arginyl-trna synthetase
C7M35_03030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M35_03031	COG3118	belongs to the thioredoxin family
C7M35_03032	COG0492	ferredoxin-NADP+ reductase activity
C7M35_03035	COG3118	belongs to the thioredoxin family
C7M35_03038	COG1846	Transcriptional regulator
C7M35_03046	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M35_03049	COG1192	Involved in chromosome partitioning
C7M35_03053	COG3293	Transposase
C7M35_03063	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M35_03075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M35_03076	COG1309	transcriptional regulator
C7M35_03078	COG1131	(ABC) transporter
C7M35_03079	COG0783	Belongs to the Dps family
C7M35_03081	COG3409	Peptidoglycan-binding domain 1 protein
C7M35_03086	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M35_03087	COG0514	ATP-dependent DNA helicase (RecQ)
C7M35_03090	COG3328	transposase activity
C7M35_03100	COG3716	PTS system mannose fructose sorbose family IID component
C7M35_03104	COG3293	Transposase
C7M35_03108	COG3293	Transposase
C7M35_03109	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M35_03112	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M35_03114	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M35_03116	COG1418	mRNA catabolic process
C7M35_03120	COG3158	transport of potassium into the cell
C7M35_03121	COG0745	RESPONSE REGULATOR receiver
C7M35_03122	COG3328	transposase activity
C7M35_03124	COG0477	Major facilitator Superfamily
C7M35_03125	COG1418	mRNA catabolic process
C7M35_03131	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M35_03131	COG0551	DNA topoisomerase type I activity
C7M35_03132	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M35_03135	COG2801	Transposase and inactivated derivatives
C7M35_03148	COG2826	transposase and inactivated derivatives, IS30 family
C7M35_03156	COG1192	Involved in chromosome partitioning
C7M35_03157	COG3842	ATPase activity
C7M35_03158	COG1653	transport
C7M35_03170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M35_03170	COG0551	DNA topoisomerase type I activity
C7M35_03176	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7M35_03181	COG0531	amino acid
C7M35_03185	COG4876	unkown