locus-tag	class	description
DKL56_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKL56_00010	COG0592	DNA-directed DNA polymerase activity
DKL56_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DKL56_00025	COG0187	DNA topoisomerase II activity
DKL56_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKL56_00035	COG0360	Binds together with S18 to 16S ribosomal RNA
DKL56_00040	COG0629	single-stranded DNA binding
DKL56_00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DKL56_00055	COG1136	(ABC) transporter
DKL56_00055	COG0577	efflux transmembrane transporter activity
DKL56_00065	COG0359	binds to the 23S rRNA
DKL56_00070	COG0305	Participates in initiation and elongation during chromosome replication
DKL56_00085	COG1285	pathogenesis
DKL56_00100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_00110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKL56_00120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_00125	COG3715	PTS system
DKL56_00130	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_00135	COG1609	Transcriptional regulator
DKL56_00165	COG3590	peptidase
DKL56_00180	COG3340	Belongs to the peptidase S51 family
DKL56_00195	COG0366	Alpha amylase catalytic
DKL56_00200	COG2188	Transcriptional regulator
DKL56_00205	COG1263	PTS System
DKL56_00205	COG2190	(PTS) system
DKL56_00205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_00210	COG0702	epimerase
DKL56_00215	COG4152	abc transporter atp-binding protein
DKL56_00220	COG1668	transmembrane transport
DKL56_00230	COG4555	ABC transporter
DKL56_00250	COG0583	DNA-binding transcription factor activity
DKL56_00255	COG0789	Transcriptional regulator
DKL56_00265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DKL56_00275	COG2084	Dehydrogenase
DKL56_00280	COG2096	Adenosyltransferase
DKL56_00295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKL56_00305	COG1011	Hydrolase
DKL56_00310	COG0656	L-ascorbic acid biosynthetic process
DKL56_00315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKL56_00320	COG1132	(ABC) transporter
DKL56_00325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKL56_00330	COG0708	Exodeoxyribonuclease III
DKL56_00340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKL56_00365	COG0583	DNA-binding transcription factor activity
DKL56_00370	COG1053	succinate dehydrogenase
DKL56_00370	COG3976	FMN-binding domain protein
DKL56_00375	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DKL56_00380	COG0402	S-adenosylhomocysteine deaminase activity
DKL56_00460	COG0745	RESPONSE REGULATOR receiver
DKL56_00465	COG5002	protein histidine kinase activity
DKL56_00480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DKL56_00485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKL56_00490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DKL56_00500	COG1132	(ABC) transporter
DKL56_00505	COG1132	(ABC) transporter
DKL56_00515	COG1122	ATPase activity
DKL56_00525	COG0501	Belongs to the peptidase M48B family
DKL56_00530	COG1704	LemA family
DKL56_00535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DKL56_00575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DKL56_00585	COG2801	Transposase and inactivated derivatives
DKL56_00590	COG1126	abc transporter atp-binding protein
DKL56_00595	COG0765	amino acid transport
DKL56_00600	COG2094	Belongs to the DNA glycosylase MPG family
DKL56_00605	COG3189	MarR family transcriptional regulator
DKL56_00610	COG0861	Integral membrane protein TerC family
DKL56_00615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKL56_00625	COG2502	aspartate--ammonia ligase
DKL56_00645	COG0328	RNA-DNA hybrid ribonuclease activity
DKL56_00655	COG0463	Glycosyl transferase, family 2
DKL56_00655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DKL56_00665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKL56_00695	COG1181	Belongs to the D-alanine--D-alanine ligase family
DKL56_00715	COG0657	acetylesterase activity
DKL56_00715	COG2755	lipolytic protein G-D-S-L family
DKL56_00735	COG0308	aminopeptidase N
DKL56_00745	COG3104	oligopeptide transport
DKL56_00755	COG1136	(ABC) transporter
DKL56_00785	COG0411	ABC transporter
DKL56_00790	COG0410	ABC transporter
DKL56_00800	COG0588	phosphoglycerate mutase activity
DKL56_00810	COG3973	AAA domain
DKL56_00825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKL56_00845	COG3022	response to hydroperoxide
DKL56_00865	COG1136	(ABC) transporter
DKL56_00880	COG0431	NADPH-dependent FMN reductase
DKL56_00885	COG0431	NADPH-dependent FMN reductase
DKL56_00910	COG0357	Ribosomal RNA small subunit methyltransferase G
DKL56_00920	COG1192	Involved in chromosome partitioning
DKL56_00925	COG1475	DNA binding
DKL56_00930	COG4481	Protein conserved in bacteria
DKL56_00935	COG0012	GTP binding
DKL56_00945	COG1132	(ABC) transporter
DKL56_00950	COG1132	(ABC) transporter
DKL56_00955	COG1174	glycine betaine transport
DKL56_00975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKL56_00990	COG4120	Belongs to the binding-protein-dependent transport system permease family
DKL56_01005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DKL56_01005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DKL56_01020	COG3715	PTS system
DKL56_01025	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DKL56_01050	COG4989	oxidoreductase activity
DKL56_01065	COG1518	maintenance of DNA repeat elements
DKL56_01090	COG2267	carboxylic ester hydrolase activity
DKL56_01110	COG2176	DNA-directed DNA polymerase activity
DKL56_01135	COG0395	ABC-type sugar transport system, permease component
DKL56_01145	COG1653	transport
DKL56_01150	COG0583	DNA-binding transcription factor activity
DKL56_01155	COG2814	Major facilitator Superfamily
DKL56_01160	COG3976	FMN-binding domain protein
DKL56_01160	COG1053	succinate dehydrogenase
DKL56_01185	COG2409	Drug exporters of the RND superfamily
DKL56_01185	COG1033	growth of symbiont in host cell
DKL56_01200	COG1012	belongs to the aldehyde dehydrogenase family
DKL56_01210	COG0398	Pfam SNARE associated Golgi protein
DKL56_01230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DKL56_01270	COG3715	PTS system
DKL56_01275	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01285	COG1113	amino acid transport
DKL56_01290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKL56_01295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKL56_01325	COG0789	Transcriptional regulator
DKL56_01325	COG4978	Transcriptional regulator
DKL56_01330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKL56_01340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_01345	COG3715	PTS system
DKL56_01350	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01355	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKL56_01360	COG2188	Transcriptional regulator
DKL56_01365	COG2188	Transcriptional regulator
DKL56_01375	COG3715	PTS system
DKL56_01380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKL56_01390	COG2222	sugar isomerase
DKL56_01395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_01405	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01425	COG3684	Belongs to the aldolase LacD family
DKL56_01445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_01445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKL56_01445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_01480	COG3715	PTS system
DKL56_01485	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01490	COG2222	sugar isomerase
DKL56_01495	COG2222	sugar isomerase
DKL56_01520	COG0436	Aminotransferase
DKL56_01560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DKL56_01570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKL56_01575	COG4472	Bacterial protein of unknown function (DUF965)
DKL56_01580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKL56_01585	COG3906	Belongs to the UPF0473 family
DKL56_01590	COG1193	negative regulation of DNA recombination
DKL56_01595	COG3118	belongs to the thioredoxin family
DKL56_01600	COG1970	mechanosensitive ion channel activity
DKL56_01605	COG1719	4-vinyl reductase, 4VR
DKL56_01610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKL56_01615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DKL56_01620	COG0668	transmembrane transport
DKL56_01635	COG0006	proline dipeptidase activity
DKL56_01655	COG0737	Belongs to the 5'-nucleotidase family
DKL56_01665	COG0647	UMP catabolic process
DKL56_01675	COG0586	Pfam SNARE associated Golgi protein
DKL56_01680	COG0492	ferredoxin-NADP+ reductase activity
DKL56_01835	COG0438	transferase activity, transferring glycosyl groups
DKL56_01840	COG0438	transferase activity, transferring glycosyl groups
DKL56_01850	COG1368	sulfuric ester hydrolase activity
DKL56_01860	COG0557	exoribonuclease II activity
DKL56_01865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DKL56_01875	COG1253	flavin adenine dinucleotide binding
DKL56_01905	COG0572	uridine kinase
DKL56_01915	COG2188	Transcriptional regulator
DKL56_01925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_01930	COG3715	PTS system
DKL56_01935	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_01940	COG2222	sugar isomerase
DKL56_01955	COG1447	Phosphotransferase system cellobiose-specific component IIA
DKL56_01960	COG2723	6-phospho-beta-galactosidase activity
DKL56_01970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_01995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DKL56_02005	COG2188	Transcriptional regulator
DKL56_02015	COG1349	DNA-binding transcription factor activity
DKL56_02025	COG2190	(PTS) system
DKL56_02025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_02025	COG1263	PTS System
DKL56_02030	COG0737	Belongs to the 5'-nucleotidase family
DKL56_02035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DKL56_02045	COG1956	GAF domain-containing protein
DKL56_02055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKL56_02060	COG0765	amino acid transport
DKL56_02065	COG0765	amino acid transport
DKL56_02070	COG2222	sugar isomerase
DKL56_02075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKL56_02080	COG4166	transmembrane transport
DKL56_02085	COG4166	transmembrane transport
DKL56_02090	COG0601	transmembrane transport
DKL56_02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKL56_02100	COG0444	Belongs to the ABC transporter superfamily
DKL56_02105	COG4608	Belongs to the ABC transporter superfamily
DKL56_02115	COG2188	Transcriptional regulator
DKL56_02125	COG0656	L-ascorbic acid biosynthetic process
DKL56_02130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DKL56_02145	COG3091	SprT-like family
DKL56_02155	COG1132	(ABC) transporter
DKL56_02165	COG1705	Flagellar rod assembly protein muramidase FlgJ
DKL56_02175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DKL56_02180	COG4851	CamS sex pheromone cAM373 precursor
DKL56_02185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKL56_02190	COG0154	amidase activity
DKL56_02195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKL56_02200	COG1597	lipid kinase activity
DKL56_02210	COG0670	Belongs to the BI1 family
DKL56_02215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKL56_02220	COG3655	Transcriptional regulator
DKL56_02255	COG3279	Response regulator of the LytR AlgR family
DKL56_02260	COG0519	Catalyzes the synthesis of GMP from XMP
DKL56_02295	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DKL56_02300	COG1737	Transcriptional regulator
DKL56_02305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DKL56_02310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_02310	COG2190	(PTS) system
DKL56_02310	COG1263	PTS System
DKL56_02335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_02355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKL56_02370	COG0024	Methionine aminopeptidase
DKL56_02380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKL56_02385	COG0183	Belongs to the thiolase family
DKL56_02395	COG3425	synthase
DKL56_02415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKL56_02435	COG1253	flavin adenine dinucleotide binding
DKL56_02440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DKL56_02450	COG0542	response to heat
DKL56_02470	COG1393	Belongs to the ArsC family
DKL56_02495	COG2357	RelA SpoT domain protein
DKL56_02500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKL56_02505	COG0564	pseudouridine synthase activity
DKL56_02510	COG2706	6-phosphogluconolactonase activity
DKL56_02515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DKL56_02525	COG0628	permease
DKL56_02540	COG1674	ftsk spoiiie
DKL56_02545	COG1028	Short-chain dehydrogenase reductase Sdr
DKL56_02550	COG1426	Protein conserved in bacteria
DKL56_02555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKL56_02580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DKL56_02585	COG1418	mRNA catabolic process
DKL56_02590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKL56_02595	COG1739	Uncharacterized protein family UPF0029
DKL56_02600	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DKL56_02615	COG0653	protein targeting
DKL56_02630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DKL56_02635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DKL56_02640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DKL56_02645	COG0492	ferredoxin-NADP+ reductase activity
DKL56_02650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKL56_02655	COG0556	nucleotide-excision repair
DKL56_02660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKL56_02670	COG1660	Displays ATPase and GTPase activities
DKL56_02685	COG0740	serine-type endopeptidase activity
DKL56_02700	COG0531	amino acid
DKL56_02725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKL56_02730	COG2390	Transcriptional regulator
DKL56_02740	COG0126	phosphoglycerate kinase activity
DKL56_02770	COG0656	L-ascorbic acid biosynthetic process
DKL56_02795	COG0561	phosphatase activity
DKL56_02800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DKL56_02805	COG0280	phosphate acetyltransferase
DKL56_02810	COG0802	atpase or kinase
DKL56_02820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DKL56_02835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKL56_02840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKL56_02865	COG0438	transferase activity, transferring glycosyl groups
DKL56_02875	COG0477	Major facilitator Superfamily
DKL56_02895	COG2217	Heavy metal translocating P-type atpase
DKL56_02910	COG0561	phosphatase activity
DKL56_02915	COG0531	amino acid
DKL56_02930	COG3069	C4-dicarboxylate transmembrane transporter activity
DKL56_02935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DKL56_02965	COG0827	DNA restriction-modification system
DKL56_02970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DKL56_02980	COG0561	phosphatase activity
DKL56_02990	COG0582	viral genome integration into host DNA
DKL56_03005	COG0583	DNA-binding transcription factor activity
DKL56_03010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DKL56_03020	COG1482	cell wall glycoprotein biosynthetic process
DKL56_03030	COG0745	RESPONSE REGULATOR receiver
DKL56_03035	COG3850	Histidine kinase
DKL56_03035	COG5002	protein histidine kinase activity
DKL56_03045	COG1368	sulfuric ester hydrolase activity
DKL56_03055	COG0166	Belongs to the GPI family
DKL56_03060	COG0477	Major facilitator Superfamily
DKL56_03070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKL56_03085	COG2207	Transcriptional regulator
DKL56_03095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_03100	COG2723	6-phospho-beta-galactosidase activity
DKL56_03105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_03110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKL56_03125	COG1122	ATPase activity
DKL56_03155	COG1263	PTS System
DKL56_03155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_03155	COG2190	(PTS) system
DKL56_03160	COG3711	transcriptional antiterminator
DKL56_03165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKL56_03170	COG1435	thymidine kinase activity
DKL56_03175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DKL56_03180	COG2890	protein-(glutamine-N5) methyltransferase activity
DKL56_03185	COG0009	L-threonylcarbamoyladenylate synthase
DKL56_03190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DKL56_03195	COG0356	it plays a direct role in the translocation of protons across the membrane
DKL56_03200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKL56_03205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DKL56_03210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKL56_03215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DKL56_03220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DKL56_03225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DKL56_03240	COG1077	Cell shape determining protein MreB Mrl
DKL56_03245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DKL56_03255	COG0772	Belongs to the SEDS family
DKL56_03260	COG0589	response to stress
DKL56_03275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DKL56_03285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DKL56_03290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DKL56_03295	COG1104	cysteine desulfurase activity
DKL56_03300	COG0301	tRNA thio-modification
DKL56_03305	COG0525	valine-tRNA ligase activity
DKL56_03315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKL56_03320	COG2003	Belongs to the UPF0758 family
DKL56_03325	COG1077	Cell shape determining protein MreB Mrl
DKL56_03330	COG1792	Involved in formation and maintenance of cell shape
DKL56_03350	COG2001	Belongs to the MraZ family
DKL56_03355	COG0275	rRNA processing
DKL56_03370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKL56_03375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DKL56_03380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKL56_03385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKL56_03395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DKL56_03400	COG1799	cell septum assembly
DKL56_03415	COG3599	regulation of cell shape
DKL56_03420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DKL56_03425	COG1278	Cold shock
DKL56_03430	COG0494	nUDIX hydrolase
DKL56_03445	COG1104	cysteine desulfurase activity
DKL56_03455	COG0482	sulfurtransferase activity
DKL56_03460	COG0406	alpha-ribazole phosphatase activity
DKL56_03470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKL56_03480	COG1121	(ABC) transporter
DKL56_03495	COG1597	lipid kinase activity
DKL56_03510	COG0242	peptide deformylase activity
DKL56_03520	COG0772	Belongs to the SEDS family
DKL56_03525	COG4471	UPF0298 protein
DKL56_03530	COG0742	ribosomal rna small subunit methyltransferase
DKL56_03535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DKL56_03540	COG3480	Lon protease (S16) C-terminal proteolytic domain
DKL56_03545	COG1555	photosystem II stabilization
DKL56_03550	COG2333	competence protein COMEC
DKL56_03550	COG0658	competence protein
DKL56_03555	COG1466	dna polymerase III delta subunit
DKL56_03560	COG0268	Binds directly to 16S ribosomal RNA
DKL56_03565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DKL56_03580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKL56_03585	COG0544	peptidyl-prolyl cis-trans isomerase activity
DKL56_03590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DKL56_03595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DKL56_03600	COG0322	excinuclease ABC activity
DKL56_03605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DKL56_03615	COG1234	tRNA 3'-trailer cleavage
DKL56_03620	COG0300	oxidoreductase activity
DKL56_03630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DKL56_03635	COG0737	Belongs to the 5'-nucleotidase family
DKL56_03645	COG0587	DNA-directed DNA polymerase activity
DKL56_03650	COG0205	6-phosphofructokinase activity
DKL56_03660	COG2996	Protein conserved in bacteria
DKL56_03670	COG0456	acetyltransferase
DKL56_03675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKL56_03680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKL56_03685	COG1187	pseudouridine synthase activity
DKL56_03700	COG1959	2 iron, 2 sulfur cluster binding
DKL56_03705	COG1388	LysM domain
DKL56_03705	COG3942	CHAP domain
DKL56_03710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DKL56_03715	COG0539	negative regulation of cytoplasmic translation
DKL56_03720	COG1160	GTP binding
DKL56_03725	COG0776	regulation of translation
DKL56_03740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKL56_03745	COG0617	tRNA 3'-terminal CCA addition
DKL56_03750	COG1272	protein, Hemolysin III
DKL56_03755	COG1307	EDD domain protein, DegV family
DKL56_03760	COG4479	Belongs to the UPF0346 family
DKL56_03765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DKL56_03770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKL56_03775	COG0758	DNA mediated transformation
DKL56_03780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKL56_03825	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DKL56_03830	COG4974	Belongs to the 'phage' integrase family
DKL56_03840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DKL56_03850	COG2814	Major facilitator Superfamily
DKL56_03855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DKL56_03860	COG0187	DNA topoisomerase II activity
DKL56_03865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKL56_03870	COG0583	DNA-binding transcription factor activity
DKL56_03875	COG1227	inorganic diphosphatase activity
DKL56_03885	COG4974	Belongs to the 'phage' integrase family
DKL56_03895	COG1307	EDD domain protein, DegV family
DKL56_03920	COG0564	pseudouridine synthase activity
DKL56_03930	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DKL56_03945	COG0116	Belongs to the methyltransferase superfamily
DKL56_03955	COG3599	regulation of cell shape
DKL56_03960	COG4474	Belongs to the UPF0398 family
DKL56_03965	COG3331	DNA recombination
DKL56_03975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKL56_03980	COG3935	DnaD domain protein
DKL56_03985	COG0017	Asparaginyl-tRNA synthetase
DKL56_03995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKL56_03995	COG1199	ATP-dependent helicase activity
DKL56_04000	COG1074	ATP-dependent DNA helicase activity
DKL56_04005	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DKL56_04025	COG1304	FMN binding
DKL56_04030	COG0561	phosphatase activity
DKL56_04035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DKL56_04035	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DKL56_04065	COG1131	(ABC) transporter
DKL56_04075	COG1131	(ABC) transporter
DKL56_04080	COG1725	Transcriptional regulator
DKL56_04085	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKL56_04095	COG2384	SAM-dependent methyltransferase
DKL56_04115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKL56_04120	COG0358	DNA primase activity
DKL56_04125	COG0751	glycine-tRNA ligase activity
DKL56_04130	COG0752	glycyl-tRNA synthetase alpha subunit
DKL56_04135	COG1381	Involved in DNA repair and RecF pathway recombination
DKL56_04140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DKL56_04145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DKL56_04150	COG1702	phosphate starvation-inducible protein PhoH
DKL56_04160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKL56_04165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DKL56_04170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKL56_04175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKL56_04180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKL56_04185	COG0436	Aminotransferase
DKL56_04190	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DKL56_04195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKL56_04205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DKL56_04220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKL56_04230	COG2264	protein methyltransferase activity
DKL56_04235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKL56_04245	COG0039	L-malate dehydrogenase activity
DKL56_04250	COG1053	succinate dehydrogenase
DKL56_04255	COG0114	fumarate hydratase activity
DKL56_04265	COG1114	Component of the transport system for branched-chain amino acids
DKL56_04270	COG3142	Participates in the control of copper homeostasis
DKL56_04275	COG1446	asparaginase
DKL56_04285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DKL56_04305	COG2011	ABC-type metal ion transport system permease component
DKL56_04310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKL56_04360	COG0789	Transcriptional regulator
DKL56_04405	COG1307	EDD domain protein, DegV family
DKL56_04410	COG0148	phosphopyruvate hydratase activity
DKL56_04415	COG2217	Heavy metal translocating P-type atpase
DKL56_04430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DKL56_04430	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DKL56_04435	COG0481	GTPase activity
DKL56_04440	COG0484	heat shock protein binding
DKL56_04445	COG0443	Heat shock 70 kDa protein
DKL56_04450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DKL56_04455	COG1420	regulation of RNA biosynthetic process
DKL56_04460	COG0196	riboflavin kinase activity
DKL56_04465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DKL56_04470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKL56_04475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DKL56_04485	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DKL56_04490	COG0195	Participates in both transcription termination and antitermination
DKL56_04495	COG0779	Required for maturation of 30S ribosomal subunits
DKL56_04505	COG0442	prolyl-tRNA aminoacylation
DKL56_04510	COG0750	zinc metalloprotease
DKL56_04515	COG4589	Belongs to the CDS family
DKL56_04520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DKL56_04525	COG0233	cytoplasmic translational termination
DKL56_04530	COG0528	UMP kinase activity
DKL56_04535	COG1053	succinate dehydrogenase
DKL56_04540	COG0583	DNA-binding transcription factor activity
DKL56_04555	COG0052	Belongs to the universal ribosomal protein uS2 family
DKL56_04565	COG0204	Acyl-transferase
DKL56_04570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DKL56_04580	COG1132	(ABC) transporter
DKL56_04585	COG1132	(ABC) transporter
DKL56_04590	COG3763	UPF0154 protein
DKL56_04595	COG4224	UPF0291 protein
DKL56_04600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKL56_04615	COG0336	Belongs to the RNA methyltransferase TrmD family
DKL56_04620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKL56_04625	COG0228	four-way junction DNA binding
DKL56_04630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DKL56_04635	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DKL56_04640	COG0531	amino acid
DKL56_04650	COG0552	protein localization to endoplasmic reticulum
DKL56_04655	COG1196	nuclear chromosome segregation
DKL56_04660	COG0571	ribonuclease III activity
DKL56_04665	COG0747	negative chemotaxis
DKL56_04685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKL56_04690	COG0601	transmembrane transport
DKL56_04695	COG4608	Belongs to the ABC transporter superfamily
DKL56_04705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKL56_04710	COG0416	fatty acid biosynthetic process
DKL56_04715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DKL56_04730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKL56_04740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKL56_04745	COG1162	GTPase activity
DKL56_04750	COG0515	serine threonine protein kinase
DKL56_04750	COG2815	serine threonine protein kinase
DKL56_04760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DKL56_04760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKL56_04765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DKL56_04770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKL56_04775	COG1758	RNA polymerase activity
DKL56_04780	COG0194	GDP metabolic process
DKL56_04795	COG0497	DNA recombination
DKL56_04800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DKL56_04810	COG1722	exodeoxyribonuclease VII activity
DKL56_04815	COG1570	exodeoxyribonuclease VII activity
DKL56_04825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKL56_04830	COG1302	Protein conserved in bacteria
DKL56_04835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKL56_04840	COG0006	proline dipeptidase activity
DKL56_04845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DKL56_04850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DKL56_04855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKL56_04890	COG2936	dipeptidyl-peptidase activity
DKL56_04905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DKL56_04910	COG0505	Belongs to the CarA family
DKL56_04915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DKL56_04930	COG0167	dihydroorotate dehydrogenase activity
DKL56_04935	COG0284	orotidine-5'-phosphate decarboxylase activity
DKL56_04940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKL56_04960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKL56_04980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DKL56_04985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKL56_04995	COG2971	BadF BadG BcrA BcrD
DKL56_05000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKL56_05005	COG0072	phenylalanine-tRNA ligase activity
DKL56_05010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DKL56_05015	COG1733	regulation of RNA biosynthetic process
DKL56_05020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKL56_05030	COG0706	membrane insertase activity
DKL56_05035	COG5002	protein histidine kinase activity
DKL56_05040	COG0745	RESPONSE REGULATOR receiver
DKL56_05050	COG1323	Belongs to the UPF0348 family
DKL56_05055	COG0799	negative regulation of ribosome biogenesis
DKL56_05060	COG1713	HD superfamily hydrolase involved in NAD metabolism
DKL56_05065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DKL56_05070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DKL56_05075	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DKL56_05080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKL56_05085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKL56_05090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DKL56_05095	COG0765	amino acid transport
DKL56_05100	COG0765	amino acid transport
DKL56_05105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKL56_05120	COG1484	DNA-dependent DNA replication
DKL56_05125	COG3611	Membrane attachment protein
DKL56_05130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKL56_05135	COG0237	dephospho-CoA kinase activity
DKL56_05140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DKL56_05145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKL56_05145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKL56_05160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKL56_05165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKL56_05170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKL56_05175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKL56_05180	COG4473	ABC transporter
DKL56_05185	COG1131	(ABC) transporter
DKL56_05190	COG0537	adenosine 5'-monophosphoramidase activity
DKL56_05200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKL56_05205	COG3481	metal-dependent phosphohydrolase, HD sub domain
DKL56_05210	COG4717	serine-type aminopeptidase activity
DKL56_05215	COG0420	3'-5' exonuclease activity
DKL56_05220	COG3679	Belongs to the UPF0342 family
DKL56_05225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKL56_05230	COG0564	pseudouridine synthase activity
DKL56_05250	COG3715	PTS system
DKL56_05255	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_05260	COG2267	carboxylic ester hydrolase activity
DKL56_05300	COG0018	arginyl-trna synthetase
DKL56_05305	COG1376	ErfK ybiS ycfS ynhG family protein
DKL56_05310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DKL56_05315	COG1686	Belongs to the peptidase S11 family
DKL56_05335	COG2244	polysaccharide biosynthetic process
DKL56_05340	COG0495	leucyl-tRNA aminoacylation
DKL56_05365	COG2814	Major facilitator Superfamily
DKL56_05370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DKL56_05385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_05390	COG2723	6-phospho-beta-galactosidase activity
DKL56_05395	COG1737	Transcriptional regulator
DKL56_05450	COG0513	Belongs to the DEAD box helicase family
DKL56_05455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DKL56_05460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKL56_05465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DKL56_05470	COG1862	Preprotein translocase
DKL56_05475	COG2255	four-way junction helicase activity
DKL56_05480	COG0632	four-way junction helicase activity
DKL56_05485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DKL56_05490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DKL56_05510	COG0459	protein refolding
DKL56_05515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DKL56_05520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DKL56_05525	COG0488	(ABC) transporter
DKL56_05530	COG0384	phenazine biosynthesis protein PhzF
DKL56_05540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKL56_05550	COG1214	PFAM Peptidase M22, glycoprotease
DKL56_05555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DKL56_05575	COG0470	DNA polymerase III
DKL56_05580	COG3870	Protein conserved in bacteria
DKL56_05585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DKL56_05595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKL56_05600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DKL56_05605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DKL56_05615	COG0590	tRNA wobble adenosine to inosine editing
DKL56_05620	COG2813	Specifically methylates the guanine in position
DKL56_05635	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DKL56_05640	COG0704	Plays a role in the regulation of phosphate uptake
DKL56_05645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKL56_05650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKL56_05655	COG0581	inorganic phosphate transmembrane transporter activity
DKL56_05660	COG0573	inorganic phosphate transmembrane transporter activity
DKL56_05665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKL56_05670	COG0081	regulation of translation
DKL56_05675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DKL56_05680	COG0250	Participates in transcription elongation, termination and antitermination
DKL56_05690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKL56_05705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKL56_05710	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DKL56_05715	COG0215	cysteine-tRNA ligase activity
DKL56_05720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKL56_05730	COG0756	dUTP diphosphatase activity
DKL56_05760	COG0588	phosphoglycerate mutase activity
DKL56_05770	COG1230	cation diffusion facilitator family transporter
DKL56_05775	COG0588	phosphoglycerate mutase activity
DKL56_05810	COG1131	(ABC) transporter
DKL56_05820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_05825	COG2723	6-phospho-beta-galactosidase activity
DKL56_05910	COG0383	alpha-mannosidase activity
DKL56_05915	COG0383	alpha-mannosidase activity
DKL56_05920	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DKL56_05920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_05920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_05925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_05965	COG1136	(ABC) transporter
DKL56_05970	COG1136	(ABC) transporter
DKL56_05970	COG0577	efflux transmembrane transporter activity
DKL56_05985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKL56_05990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKL56_05995	COG0101	tRNA pseudouridine synthase activity
DKL56_06000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKL56_06005	COG1122	ATPase activity
DKL56_06015	COG0203	ribosomal protein L17
DKL56_06020	COG0202	RNA polymerase activity
DKL56_06025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DKL56_06030	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DKL56_06035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKL56_06040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DKL56_06045	COG0563	adenylate kinase activity
DKL56_06055	COG0200	Binds to the 23S rRNA
DKL56_06060	COG1841	ribosomal large subunit assembly
DKL56_06065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DKL56_06070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DKL56_06075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DKL56_06080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DKL56_06085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKL56_06090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DKL56_06095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DKL56_06100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DKL56_06105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DKL56_06110	COG0255	Belongs to the universal ribosomal protein uL29 family
DKL56_06115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DKL56_06120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DKL56_06125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DKL56_06135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DKL56_06140	COG0089	rRNA binding
DKL56_06145	COG0088	Forms part of the polypeptide exit tunnel
DKL56_06150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKL56_06155	COG0051	transcription antitermination factor activity, RNA binding
DKL56_06160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKL56_06165	COG0049	tRNA binding
DKL56_06170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKL56_06175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DKL56_06185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKL56_06190	COG0085	RNA polymerase activity
DKL56_06195	COG0542	response to heat
DKL56_06225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DKL56_06230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKL56_06235	COG0406	alpha-ribazole phosphatase activity
DKL56_06240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKL56_06265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DKL56_06270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DKL56_06275	COG0193	aminoacyl-tRNA hydrolase activity
DKL56_06285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKL56_06290	COG0736	holo-[acyl-carrier-protein] synthase activity
DKL56_06300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKL56_06305	COG0254	rRNA binding
DKL56_06320	COG0765	amino acid transport
DKL56_06325	COG0765	amino acid transport
DKL56_06340	COG0531	amino acid
DKL56_06350	COG1053	succinate dehydrogenase
DKL56_06375	COG2723	6-phospho-beta-galactosidase activity
DKL56_06385	COG2190	(PTS) system
DKL56_06385	COG1263	PTS System
DKL56_06385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_06400	COG3527	Alpha-acetolactate decarboxylase
DKL56_06410	COG0519	Catalyzes the synthesis of GMP from XMP
DKL56_06435	COG4690	dipeptidase activity
DKL56_06440	COG1940	carbohydrate kinase activity
DKL56_06460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKL56_06460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_06465	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_06475	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DKL56_06475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DKL56_06485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKL56_06490	COG0504	CTP synthase activity
DKL56_06495	COG3343	RNA polymerase activity
DKL56_06515	COG1078	dGTPase activity
DKL56_06525	COG1132	(ABC) transporter
DKL56_06530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKL56_06540	COG1263	PTS System
DKL56_06540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_06560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_06565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKL56_06575	COG1609	Transcriptional regulator
DKL56_06580	COG1940	carbohydrate kinase activity
DKL56_06585	COG2723	6-phospho-beta-galactosidase activity
DKL56_06595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DKL56_06600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKL56_06605	COG4466	Protein conserved in bacteria
DKL56_06610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKL56_06620	COG0084	hydrolase, TatD family'
DKL56_06625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKL56_06625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKL56_06630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DKL56_06640	COG2131	deaminase
DKL56_06665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKL56_06670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKL56_06680	COG3579	cysteine-type endopeptidase activity
DKL56_06710	COG1744	ABC transporter substrate-binding protein PnrA-like
DKL56_06715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKL56_06720	COG1418	mRNA catabolic process
DKL56_06730	COG0393	Putative heavy-metal-binding
DKL56_06740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKL56_06745	COG1368	sulfuric ester hydrolase activity
DKL56_06750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DKL56_06755	COG1316	TRANSCRIPTIONal
DKL56_06780	COG3414	Phosphotransferase system galactitol-specific IIB component
DKL56_06785	COG3775	system Galactitol-specific IIC component
DKL56_06795	COG0235	Class ii aldolase
DKL56_06800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DKL56_06805	COG0791	NLP P60 protein
DKL56_06810	COG3103	Sh3 type 3 domain protein
DKL56_06810	COG1388	LysM domain
DKL56_06810	COG0791	NLP P60 protein
DKL56_06815	COG0791	NLP P60 protein
DKL56_06830	COG1136	(ABC) transporter
DKL56_06830	COG0577	efflux transmembrane transporter activity
DKL56_06855	COG2184	nucleotidyltransferase activity
DKL56_06870	COG2132	Multicopper oxidase
DKL56_06875	COG4990	cell redox homeostasis
DKL56_06885	COG2966	Psort location CytoplasmicMembrane, score
DKL56_06890	COG0488	(ABC) transporter
DKL56_06900	COG1316	TRANSCRIPTIONal
DKL56_06905	COG1164	Oligoendopeptidase f
DKL56_06910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKL56_06915	COG1126	abc transporter atp-binding protein
DKL56_06920	COG0765	amino acid transport
DKL56_06925	COG1304	FMN binding
DKL56_06930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKL56_06935	COG1121	(ABC) transporter
DKL56_06950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_06950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKL56_06950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKL56_06955	COG1105	Belongs to the carbohydrate kinase PfkB family
DKL56_06960	COG1349	DNA-binding transcription factor activity
DKL56_06965	COG2814	Major facilitator Superfamily
DKL56_06980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DKL56_06985	COG1053	succinate dehydrogenase
DKL56_06990	COG1053	succinate dehydrogenase
DKL56_06990	COG3976	FMN-binding domain protein
DKL56_07000	COG1053	succinate dehydrogenase
DKL56_07005	COG0583	DNA-binding transcription factor activity
DKL56_07020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKL56_07030	COG0789	Transcriptional regulator
DKL56_07035	COG1309	transcriptional regulator
DKL56_07040	COG0481	GTPase activity
DKL56_07045	COG0588	phosphoglycerate mutase activity
DKL56_07065	COG0569	domain protein
DKL56_07065	COG0475	glutathione-regulated potassium exporter activity
DKL56_07080	COG1388	LysM domain
DKL56_07080	COG1705	Flagellar rod assembly protein muramidase FlgJ
DKL56_07125	COG3158	transport of potassium into the cell
DKL56_07135	COG3590	peptidase
DKL56_07140	COG2814	Major facilitator Superfamily
DKL56_07150	COG0367	asparagine synthase
DKL56_07165	COG2818	Glycosylase
DKL56_07175	COG3639	organic phosphonate transmembrane transporter activity
DKL56_07180	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DKL56_07195	COG0589	response to stress
DKL56_07200	COG2365	Tyrosine phosphatase family
DKL56_07210	COG0519	Catalyzes the synthesis of GMP from XMP
DKL56_07210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKL56_07245	COG2723	6-phospho-beta-galactosidase activity
DKL56_07250	COG2723	6-phospho-beta-galactosidase activity
DKL56_07255	COG1263	PTS System
DKL56_07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_07255	COG2190	(PTS) system
DKL56_07260	COG3711	transcriptional antiterminator
DKL56_07275	COG4932	domain protein
DKL56_07275	COG4886	Leucine-rich repeat (LRR) protein
DKL56_07290	COG4932	domain protein
DKL56_07290	COG4886	Leucine-rich repeat (LRR) protein
DKL56_07330	COG4886	Leucine-rich repeat (LRR) protein
DKL56_07330	COG4932	domain protein
DKL56_07335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DKL56_07340	COG2365	Tyrosine phosphatase family
DKL56_07345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DKL56_07350	COG0351	phosphomethylpyrimidine kinase
DKL56_07355	COG3442	glutamine amidotransferase
DKL56_07365	COG0583	DNA-binding transcription factor activity
DKL56_07385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKL56_07390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKL56_07395	COG0516	GMP reductase activity
DKL56_07410	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_07415	COG3715	PTS system
DKL56_07420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_07420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKL56_07425	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DKL56_07425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DKL56_07430	COG0583	DNA-binding transcription factor activity
DKL56_07435	COG1053	succinate dehydrogenase
DKL56_07445	COG1053	succinate dehydrogenase
DKL56_07445	COG0431	NADPH-dependent FMN reductase
DKL56_07445	COG3976	FMN-binding domain protein
DKL56_07455	COG0583	DNA-binding transcription factor activity
DKL56_07460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DKL56_07470	COG3842	ATPase activity
DKL56_07485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DKL56_07490	COG0436	Aminotransferase
DKL56_07495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DKL56_07500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKL56_07505	COG1473	amidohydrolase
DKL56_07510	COG2171	N-acyltransferase activity
DKL56_07515	COG0019	diaminopimelate decarboxylase activity
DKL56_07520	COG0527	aspartate kinase activity
DKL56_07525	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DKL56_07535	COG2207	Transcriptional regulator
DKL56_07535	COG3708	Transcriptional regulator
DKL56_07550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DKL56_07565	COG1028	Short-chain dehydrogenase reductase Sdr
DKL56_07575	COG0789	Transcriptional regulator
DKL56_07580	COG1063	alcohol dehydrogenase
DKL56_07590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DKL56_07615	COG3716	PTS system mannose fructose sorbose family IID component
DKL56_07625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKL56_07625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKL56_07635	COG0730	response to heat
DKL56_07645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKL56_07650	COG0542	response to heat
DKL56_07655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKL56_07690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DKL56_07695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKL56_07700	COG1696	Membrane protein involved in D-alanine export
DKL56_07705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKL56_07730	COG2217	Heavy metal translocating P-type atpase
DKL56_07745	COG1136	(ABC) transporter
DKL56_07745	COG0577	efflux transmembrane transporter activity
DKL56_07745	COG1136	(ABC) transporter
DKL56_07745	COG0577	efflux transmembrane transporter activity
DKL56_07750	COG0363	glucosamine-6-phosphate deaminase activity
DKL56_07770	COG1428	Deoxynucleoside kinase
DKL56_07775	COG1428	Deoxynucleoside kinase
DKL56_07780	COG0765	amino acid transport
DKL56_07785	COG1126	abc transporter atp-binding protein
DKL56_07795	COG0561	phosphatase activity
DKL56_07800	COG2252	PERMEase
DKL56_07805	COG0471	metal ion transport
DKL56_07810	COG2252	PERMEase
DKL56_07815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DKL56_07820	COG0028	Belongs to the TPP enzyme family
DKL56_07825	COG0445	tRNA wobble uridine modification
DKL56_07830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DKL56_07835	COG0706	membrane insertase activity
DKL56_07840	COG0594	ribonuclease P activity
DKL56_07845	COG0230	Belongs to the bacterial ribosomal protein bL34 family