locus-tag	class	description
A3P31_00020	ENOG4107QJE	Chromosome Partitioning Protein
A3P31_00045	ENOG4108KU3	Integrase
A3P31_00050	ENOG4105Z8H	single-stranded DNA-binding protein
A3P31_00095	ENOG4107QJE	Chromosome Partitioning Protein
A3P31_00120	ENOG4108KU3	Integrase
A3P31_00125	ENOG4105Z8H	single-stranded DNA-binding protein
A3P31_00270	ENOG4105E5H	Transposase
A3P31_00540	ENOG4105D06	uba thif-type nad fad binding protein
A3P31_00580	ENOG4105CDU	Replicative dna helicase
A3P31_00585	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A3P31_00600	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A3P31_00605	ENOG4108UUM	single-stranded DNA-binding protein
A3P31_00610	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A3P31_00615	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A3P31_00620	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A3P31_00625	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A3P31_00635	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A3P31_00640	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A3P31_00645	ENOG4105VG0	50S ribosomal protein l34
A3P31_00650	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A3P31_00655	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A3P31_00660	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A3P31_00665	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A3P31_00670	ENOG4105C7K	acetolactate synthase
A3P31_00675	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A3P31_00685	ENOG4105C98	muts2 protein
A3P31_00700	ENOG4105C54	Major Facilitator superfamily
A3P31_00715	ENOG4105CXI	aluminum resistance protein
A3P31_00725	ENOG4105E5D	amino acid
A3P31_00730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A3P31_00745	ENOG4105C59	p-type ATPase
A3P31_00760	ENOG4105NA0	Transcriptional regulator
A3P31_00775	ENOG4107YDN	peptide deformylase
A3P31_00790	ENOG4105C7N	Xanthine uracil vitamin C permease
A3P31_00800	ENOG4105C7N	Xanthine uracil vitamin C permease
A3P31_00810	ENOG4105C7N	Xanthine uracil vitamin C permease
A3P31_00820	ENOG4105ZMH	deoxynucleoside kinase
A3P31_00825	ENOG4105ZMH	deoxynucleoside kinase
A3P31_00830	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A3P31_00835	ENOG4105CV8	reductase
A3P31_00845	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A3P31_00855	ENOG4105DTQ	mandelate racemase muconate lactonizing
A3P31_00875	ENOG4105CK1	PTS System
A3P31_00885	ENOG4105DIH	basic membrane
A3P31_00905	ENOG4108JJ8	(ABC) transporter
A3P31_00910	ENOG4108JJ9	ABC, transporter
A3P31_00915	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A3P31_00920	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A3P31_00945	ENOG4105DT3	PTS system, galactitol-specific IIc component
A3P31_00975	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3P31_01010	ENOG4108JJA	ABC, transporter
A3P31_01060	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
A3P31_01065	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A3P31_01070	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
A3P31_01075	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
A3P31_01085	ENOG410605W	Major Facilitator
A3P31_01095	ENOG4105CK1	PTS System
A3P31_01110	ENOG4105CUB	amino acid
A3P31_01210	ENOG4105ETZ	PTS System
A3P31_01215	ENOG4105F3R	pts system mannose fructose sorbose family iid
A3P31_01235	ENOG4108Z86	Glutamine amidotransferase
A3P31_01245	ENOG4105CU9	asparagine synthetase A
A3P31_01250	ENOG4108UZ3	Transporter
A3P31_01255	ENOG4105CUB	amino acid
A3P31_01260	ENOG4105F1K	Glutamine amidotransferase
A3P31_01265	ENOG4105DWF	phosphomethylpyrimidine kinase
A3P31_01270	ENOG4105M2Z	protein tyrosine serine phosphatase
A3P31_01275	ENOG4105ETE	Transcriptional regulator (LacI family
A3P31_01280	ENOG4108HKT	sucrose-6-phosphate hydrolase
A3P31_01285	ENOG4105C5Y	PTS System
A3P31_01295	ENOG4108UVJ	appr-1-p processing domain protein
A3P31_01300	ENOG4105BZ1	(ABC) transporter
A3P31_01305	ENOG4108Z86	Glutamine amidotransferase
A3P31_01310	ENOG4105C6X	Major Facilitator
A3P31_01320	ENOG4105FF2	Type I DHQase
A3P31_01360	ENOG4105D1Q	UPF0246 protein
A3P31_01370	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3P31_01375	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3P31_01390	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A3P31_01405	ENOG4105DZW	Dipeptidase
A3P31_01420	ENOG4107U8T	Nadph-dependent fmn reductase
A3P31_01425	ENOG4108YYH	Nadph-dependent fmn reductase
A3P31_01450	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A3P31_01460	ENOG4107QJE	Chromosome Partitioning Protein
A3P31_01465	ENOG4105FA0	parb-like partition protein
A3P31_01470	ENOG4105VDK	protein, conserved in bacteria
A3P31_01475	ENOG4105C3G	gtp-binding protein
A3P31_01485	ENOG4105BZ1	(ABC) transporter
A3P31_01490	ENOG4105BZ1	(ABC) transporter
A3P31_01500	ENOG4105BZU	Histidine kinase
A3P31_01505	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A3P31_01510	ENOG4105CG9	aspartate racemase
A3P31_01515	ENOG4108IUX	(ABC) transporter
A3P31_01520	ENOG4105RHA	ABC transporter, permease
A3P31_01530	ENOG4105E98	transcriptional regulator DeoR family
A3P31_01535	ENOG4105DE4	1-phosphofructokinase
A3P31_01540	ENOG4105DM4	PTS System
A3P31_01550	ENOG4108HCJ	Hydrolase
A3P31_01555	ENOG41082YX	Transcriptional regulator, arsr family
A3P31_01565	ENOG4105FDK	ABC transporter
A3P31_01570	ENOG4105CC5	ABC transporter
A3P31_01585	ENOG4108KGH	TRANSCRIPTIONal
A3P31_01600	ENOG4105C5H	ABC transporter
A3P31_01605	ENOG4105DWK	Membrane
A3P31_01635	ENOG4105MTF	NrdI protein
A3P31_01655	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A3P31_01680	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3P31_01685	ENOG4105D5G	Transposase
A3P31_01695	ENOG4105E5D	amino acid
A3P31_01700	ENOG4105C19	ABC transporter
A3P31_01710	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3P31_01730	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
A3P31_01735	ENOG4106KNT	transcriptional regulator
A3P31_01760	ENOG4105EEM	helicase
A3P31_01770	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3P31_01780	ENOG4105CK1	PTS System
A3P31_01790	ENOG4108M1Z	surface protein
A3P31_01805	ENOG4105E5H	Transposase
A3P31_01835	ENOG4105CS9	pantothenic acid kinase
A3P31_01840	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A3P31_01850	ENOG4105C5Y	PTS System
A3P31_01860	ENOG4108UZ3	Transporter
A3P31_01870	ENOG4108EQA	pts system
A3P31_01880	ENOG4105F3R	pts system mannose fructose sorbose family iid
A3P31_01910	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A3P31_01930	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A3P31_01950	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A3P31_01970	ENOG4105DZW	Dipeptidase
A3P31_01980	ENOG4107Z33	ABC transporter, permease
A3P31_02005	ENOG4108U05	Transcriptional regulator
A3P31_02020	ENOG4105RD7	BadF BadG BcrA BcrD
A3P31_02030	ENOG4108IG5	Transcriptional regulator
A3P31_02035	ENOG4105EYF	MMPL domain protein
A3P31_02040	ENOG410667J	hydrolase
A3P31_02055	ENOG4105C26	Dehydrogenase
A3P31_02075	ENOG4105D9U	N-acetyltransferase
A3P31_02080	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3P31_02245	ENOG4105BZF	Glycosyl transferase (Group 1
A3P31_02250	ENOG4105W2C	Glycosyl transferase
A3P31_02260	ENOG4105E0M	Sulfatase
A3P31_02380	ENOG4105C85	amino acid
A3P31_02385	ENOG4108EKI	Dehydrogenase
A3P31_02410	ENOG4108I5C	dEAD DEAH box helicase
A3P31_02415	ENOG4105CMR	udp-glucose 4-epimerase
A3P31_02445	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
A3P31_02480	ENOG4105E66	phosphoriboisomerase A
A3P31_02515	ENOG4105FDP	GntR family transcriptional regulator
A3P31_02540	ENOG4105DAP	Nicotinate phosphoribosyltransferase
A3P31_02545	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A3P31_02550	ENOG4106F1P	AAA ATPase, central domain protein
A3P31_02560	ENOG4107SJB	teichoic acid biosynthesis
A3P31_02590	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A3P31_02595	ENOG4105C4R	Atp-dependent dna helicase
A3P31_02600	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A3P31_02610	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3P31_02615	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A3P31_02620	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3P31_02625	ENOG4105CBD	Diacylglycerol kinase
A3P31_02635	ENOG410667J	hydrolase
A3P31_02655	ENOG4108JJB	ABC transporter
A3P31_02660	ENOG4108V7D	UPF0397 protein
A3P31_02670	ENOG4105DFD	Na H antiporter
A3P31_02675	ENOG4105DA5	(ABC) transporter
A3P31_02685	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3P31_02805	ENOG4105C59	p-type ATPase
A3P31_02815	ENOG4105IJJ	transcriptional regulator, crp fnr family
A3P31_02820	ENOG4108RG0	uracil-dna glycosylase
A3P31_02850	ENOG4108YBP	pseudouridine synthase
A3P31_02855	ENOG4105BZ4	penicillin-binding protein
A3P31_02860	ENOG4105WZB	UPF0342 protein
A3P31_02865	ENOG4107RFY	SbcCD D subunit
A3P31_02875	ENOG4105EQI	Metal Dependent Phosphohydrolase
A3P31_02880	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A3P31_02895	ENOG4105K59	histidine triad (HIT) protein
A3P31_02910	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A3P31_02925	ENOG4108VDD	TRNA binding domain protein
A3P31_02930	ENOG4106N3A	copper homeostasis protein cutc
A3P31_02935	ENOG4105DFU	Cell wall formation (By similarity)
A3P31_02955	ENOG4105C2M	dna polymerase I
A3P31_02960	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A3P31_02965	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A3P31_02970	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A3P31_02985	ENOG4105C22	threonyL-tRNA synthetase
A3P31_03000	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A3P31_03005	ENOG4105VJV	50s ribosomal protein L35
A3P31_03010	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A3P31_03020	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
A3P31_03025	ENOG4105CQW	ribosome biogenesis GTPase YqeH
A3P31_03030	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A3P31_03035	ENOG4108WF2	Metal Dependent Phosphohydrolase
A3P31_03045	ENOG4105CDE	UPF0348 protein
A3P31_03060	ENOG4105GR3	Histidine kinase
A3P31_03065	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
A3P31_03070	ENOG410855V	Acylphosphatase
A3P31_03075	ENOG4108RWN	rrna methyltransferase
A3P31_03085	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3P31_03090	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A3P31_03100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A3P31_03110	ENOG4107RF6	penicillin-binding protein
A3P31_03115	ENOG4105WDJ	50S ribosomal protein L33
A3P31_03120	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A3P31_03145	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A3P31_03150	ENOG4105C5F	glutamine synthetase
A3P31_03155	ENOG4105CZM	Major Facilitator
A3P31_03160	ENOG4108HCJ	Hydrolase
A3P31_03175	ENOG4105CHU	acetyl-coa acetyltransferase
A3P31_03185	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
A3P31_03190	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3P31_03195	ENOG410902V	Modulates RecA activity (By similarity)
A3P31_03200	ENOG4105EVI	UPF0374 protein
A3P31_03215	ENOG4105C37	(CBS) domain
A3P31_03220	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A3P31_03230	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A3P31_03240	ENOG4105KRI	phosphocarrier protein (HPr
A3P31_03245	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A3P31_03250	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A3P31_03270	ENOG4105MIX	Adenylate cyclase
A3P31_03280	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3P31_03285	ENOG4105EMS	pseudouridine synthase
A3P31_03300	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A3P31_03315	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A3P31_03325	ENOG4105CNU	cell division protein FtsK
A3P31_03335	ENOG4108J6I	peptidase, M16
A3P31_03340	ENOG4105CHR	reductase
A3P31_03350	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3P31_03355	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A3P31_03360	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
A3P31_03365	ENOG4105ESV	Glycosyl transferase, family 4
A3P31_03370	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A3P31_03390	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A3P31_03395	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A3P31_03405	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A3P31_03410	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A3P31_03415	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A3P31_03420	ENOG4105C3M	thioredoxin reductase
A3P31_03445	ENOG4105CMR	udp-glucose 4-epimerase
A3P31_03450	ENOG4105IKJ	beta-galactosidase small subunit
A3P31_03460	ENOG4105CQ4	Transcriptional regulator
A3P31_03480	ENOG4105DQ6	Transposase
A3P31_03505	ENOG4105C4C	beta-galactosidase
A3P31_03515	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3P31_03520	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
A3P31_03525	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A3P31_03535	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3P31_03540	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A3P31_03550	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A3P31_03560	ENOG4105CIE	May be required for sporulation (By similarity)
A3P31_03565	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A3P31_03615	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A3P31_03620	ENOG4105BZA	Phosphoglycerate kinase
A3P31_03625	ENOG4105CP7	Triose-phosphate isomerase
A3P31_03630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3P31_03640	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A3P31_03645	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A3P31_03665	ENOG410667J	hydrolase
A3P31_03670	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A3P31_03675	ENOG4108IJ2	phosphate acetyltransferase
A3P31_03680	ENOG4105K8N	protein family UPF0079, ATPase
A3P31_03690	ENOG4105D4A	Cell wall formation (By similarity)
A3P31_03695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3P31_03700	ENOG4105F38	ABC transporter, permease
A3P31_03705	ENOG4108I5D	sulfate abc transporter
A3P31_03715	ENOG4105C8B	TIGR00159 family
A3P31_03725	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3P31_03730	ENOG410667J	hydrolase
A3P31_03735	ENOG41084I6	Protein CrcB homolog
A3P31_03740	ENOG4106A8V	Protein CrcB homolog
A3P31_03755	ENOG4108EUD	Lysophospholipase
A3P31_03765	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3P31_03775	ENOG4105CDY	transcriptional regulatory protein
A3P31_03815	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A3P31_03845	ENOG4105DG6	mannose-6-phosphate isomerase
A3P31_03855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A3P31_03860	ENOG4105BZU	Histidine kinase
A3P31_03875	ENOG4107QYV	phosphohexose isomerase
A3P31_03905	ENOG4105DMS	mur ligase
A3P31_03910	ENOG4107104	thymidine kinase
A3P31_03915	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A3P31_03920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A3P31_03925	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3P31_03930	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3P31_03940	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A3P31_03945	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A3P31_03950	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A3P31_03955	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A3P31_03960	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A3P31_03965	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A3P31_03970	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3P31_03980	ENOG4105DFF	Rod shape-determining protein mreb
A3P31_03990	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A3P31_04015	ENOG4105D1H	recombination factor protein RarA
A3P31_04025	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3P31_04030	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
A3P31_04035	ENOG4105C3J	Cysteine desulfurase
A3P31_04040	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3P31_04055	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A3P31_04060	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3P31_04070	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A3P31_04075	ENOG4105W5Q	DNA repair protein (RadC
A3P31_04080	ENOG4105DFF	Rod shape-determining protein mreb
A3P31_04105	ENOG4108V6E	Cell division protein mraZ
A3P31_04110	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A3P31_04120	ENOG4105CJN	penicillin-binding protein
A3P31_04125	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A3P31_04130	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A3P31_04135	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A3P31_04140	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
A3P31_04150	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3P31_04155	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A3P31_04170	ENOG4105MMF	Cell division protein DIVIVA
A3P31_04175	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3P31_04180	ENOG4105VEQ	Cold shock protein
A3P31_04185	ENOG4108YZ4	nudix hydrolase
A3P31_04200	ENOG4105C3J	Cysteine desulfurase
A3P31_04210	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A3P31_04225	ENOG4105C7H	Helicase, RecD TraA family
A3P31_04240	ENOG4106EHS	UPF0356 protein
A3P31_04245	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A3P31_04255	ENOG4105CI3	gtp-binding protein typa
A3P31_04260	ENOG4105CNI	cell division protein FtsW
A3P31_04270	ENOG4106H78	methyltransferase
A3P31_04275	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A3P31_04280	ENOG41063PX	domain protein
A3P31_04285	ENOG4105KQC	Competence protein
A3P31_04290	ENOG4108EC8	DNA internalization-related competence protein ComEC
A3P31_04295	ENOG4105TQK	DNA polymerase iii, delta' subunit
A3P31_04300	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A3P31_04305	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3P31_04320	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3P31_04325	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A3P31_04330	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A3P31_04335	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3P31_04340	ENOG4105KJF	protein tyrosine phosphatase
A3P31_04355	ENOG4107ZXU	DSBA oxidoreductase
A3P31_04385	ENOG4105HTX	biosynthesis protein
A3P31_04390	ENOG4107YJ4	chain length determinant protein
A3P31_04400	ENOG4105D3Q	Sugar transferase
A3P31_04405	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3P31_04410	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
A3P31_04430	ENOG4105GH9	galactofuranosyltransferase
A3P31_04440	ENOG4105D5D	udp-galactopyranose mutase
A3P31_04470	ENOG4105E5H	Transposase
A3P31_04490	ENOG4105D5G	Transposase
A3P31_04500	ENOG4105D5G	Transposase
A3P31_04530	ENOG4105D5G	Transposase
A3P31_04535	ENOG4107Z36	nucleotidyl transferase
A3P31_04545	ENOG4105C94	Transporter
A3P31_04585	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3P31_04610	ENOG4105DQ6	Transposase
A3P31_04630	ENOG4105D0M	Protease HtpX homolog
A3P31_04650	ENOG41060M0	Crispr-associated protein, cse4 family
A3P31_04665	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3P31_04670	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A3P31_04725	ENOG4107T5V	SNARE associated Golgi
A3P31_04730	ENOG4105DU0	nucleoside hydrolase
A3P31_04735	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A3P31_04740	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3P31_04745	ENOG4105EXC	Acyl-transferase
A3P31_04750	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3P31_04755	ENOG4108IXY	short-chain dehydrogenase reductase
A3P31_04765	ENOG41086FC	50S ribosomal protein l32
A3P31_04770	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A3P31_04780	ENOG4105C0B	DNA polymerase III (alpha subunit)
A3P31_04790	ENOG4105CTQ	phosphohexokinase
A3P31_04795	ENOG4105CA9	Pyruvate kinase
A3P31_04800	ENOG4105QNR	S1 RNA binding domain protein
A3P31_04815	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A3P31_04820	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A3P31_04825	ENOG4105FE9	pseudouridine synthase
A3P31_04835	ENOG4108SAX	Membrane
A3P31_04840	ENOG4105CAT	Cytidine monophosphate kinase
A3P31_04845	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A3P31_04850	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3P31_04855	ENOG4105K70	DNA-binding protein
A3P31_04865	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
A3P31_04880	ENOG4107QTH	restriction modification system DNA specificity domain
A3P31_04895	ENOG4105M6F	mutator MutT protein
A3P31_04900	ENOG4105C1J	atp-dependent rna helicase
A3P31_04910	ENOG4108JYZ	YitT family
A3P31_04915	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A3P31_04920	ENOG4108UT2	hemolysin iii
A3P31_04925	ENOG4108RCR	degv family
A3P31_04930	ENOG4105VSD	UPF0346 protein
A3P31_04940	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A3P31_04945	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3P31_04950	ENOG4105C79	DNA protecting protein DprA
A3P31_04955	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3P31_04960	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A3P31_04965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3P31_04975	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A3P31_05005	ENOG4105HMI	Membrane
A3P31_05020	ENOG4105DQ6	Transposase
A3P31_05035	ENOG4107FQX	Alpha-acetolactate decarboxylase
A3P31_05045	ENOG4105CV8	reductase
A3P31_05085	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A3P31_05090	ENOG4105C3K	feS assembly ATPase SufC
A3P31_05095	ENOG4105JRK	feS assembly protein SufD
A3P31_05105	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A3P31_05110	ENOG4105DIW	FeS assembly protein SUFB
A3P31_05130	ENOG4105DQ6	Transposase
A3P31_05175	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A3P31_05200	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
A3P31_05205	ENOG4105D1H	recombination factor protein RarA
A3P31_05225	ENOG4108UW5	maltose o-acetyltransferase
A3P31_05230	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A3P31_05235	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A3P31_05250	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A3P31_05255	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A3P31_05270	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
A3P31_05275	ENOG4108KB2	LysR family Transcriptional regulator
A3P31_05285	ENOG4105EPR	degv family
A3P31_05295	ENOG4105F23	Fibronectin-binding protein
A3P31_05305	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A3P31_05310	ENOG4105C34	Pseudouridine synthase
A3P31_05315	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A3P31_05320	ENOG4105CKU	formyltetrahydrofolate synthetase
A3P31_05330	ENOG4105EPR	degv family
A3P31_05345	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3P31_05355	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
A3P31_05360	ENOG4108UKS	UPF0398 protein
A3P31_05365	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
A3P31_05375	ENOG4105CSM	endonuclease III
A3P31_05385	ENOG4105C5S	asparaginyl-tRNA synthetase
A3P31_05395	ENOG4105DVT	helicase
A3P31_05400	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A3P31_05405	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A3P31_05430	ENOG4105BZ1	(ABC) transporter
A3P31_05445	ENOG4105DQ6	Transposase
A3P31_05455	ENOG4105D5G	Transposase
A3P31_05470	ENOG4105EV1	Ribose uptake protein RbsU
A3P31_05475	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A3P31_05480	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A3P31_05485	ENOG4105CVJ	phosphoglycerate mutase
A3P31_05500	ENOG4108ZQX	ybak prolyl-trna synthetase
A3P31_05525	ENOG4105DBI	uridine monophosphokinase
A3P31_05565	ENOG4105M2Z	protein tyrosine serine phosphatase
A3P31_05610	ENOG4105BZ1	(ABC) transporter
A3P31_05625	ENOG4105BZ1	(ABC) transporter
A3P31_05650	ENOG4105BZW	Glycerate kinase
A3P31_05665	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A3P31_05675	ENOG4105C9K	Endothelin-converting enzyme 1
A3P31_05690	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A3P31_05700	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A3P31_05705	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A3P31_05710	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A3P31_05715	ENOG4105CD3	dihydroorotase
A3P31_05720	ENOG4105CXT	aspartate transcarbamylase
A3P31_05725	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A3P31_05730	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3P31_05735	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3P31_05740	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A3P31_05755	ENOG4107S90	membrAne
A3P31_05760	ENOG4105K8R	UPF0145 protein
A3P31_05765	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3P31_05800	ENOG4105CZV	ABC transporter
A3P31_05805	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
A3P31_05810	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A3P31_05815	ENOG4105EGD	dinuclear metal center protein, YbgI family
A3P31_05830	ENOG4105CDA	abc transporter atp-binding protein
A3P31_05835	ENOG4108HW4	amino acid AbC transporter
A3P31_05840	ENOG4105E5Q	amino acid AbC transporter
A3P31_05845	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A3P31_05850	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A3P31_05855	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A3P31_05860	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A3P31_05865	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
A3P31_05870	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A3P31_05875	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A3P31_05880	ENOG4105C9A	Phoh family
A3P31_05885	ENOG4105KTH	gatB Yqey
A3P31_05890	ENOG4105VCC	30S ribosomal protein S21
A3P31_05895	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A3P31_05900	ENOG4105VG1	fes assembly suf system protein
A3P31_05905	ENOG4105EJQ	L-serine dehydratase
A3P31_05915	ENOG4107AYK	membrAne
A3P31_05940	ENOG4105E0X	reductase
A3P31_05945	ENOG4105CHM	Aminotransferase
A3P31_05950	ENOG4105C9M	aspartyl-trna synthetase
A3P31_05955	ENOG4105CUT	histidyl-tRNA synthetase
A3P31_05960	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A3P31_05965	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A3P31_05975	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3P31_05980	ENOG4108Z66	YbaK ebsC protein
A3P31_05990	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A3P31_05995	ENOG4105HDK	L-asparaginase
A3P31_06005	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A3P31_06010	ENOG4107EFR	Flavocytochrome c
A3P31_06015	ENOG4105C9Q	fumarate hydratase class II
A3P31_06020	ENOG4108UMI	ABC transporter, permease
A3P31_06025	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A3P31_06030	ENOG4105D01	(LipO)protein
A3P31_06065	ENOG4107QHE	Choloylglycine hydrolase
A3P31_06070	ENOG4105C5H	ABC transporter
A3P31_06095	ENOG4106P55	Transcriptional regulator
A3P31_06110	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A3P31_06115	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A3P31_06120	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A3P31_06125	ENOG4107SC7	Inner membrane transporter yjeM
A3P31_06130	ENOG4105DQ6	Transposase
A3P31_06140	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A3P31_06145	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A3P31_06150	ENOG4108Z6X	(sortase) family
A3P31_06155	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A3P31_06160	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A3P31_06165	ENOG4105CFG	Acts as a chaperone (By similarity)
A3P31_06170	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3P31_06175	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A3P31_06185	ENOG4105C5H	ABC transporter
A3P31_06190	ENOG4105DTN	riboflavin biosynthesis protein ribF
A3P31_06195	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3P31_06200	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A3P31_06205	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A3P31_06215	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
A3P31_06220	ENOG4105CHV	Transcription elongation factor NusA
A3P31_06225	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A3P31_06235	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3P31_06240	ENOG4105DZP	Membrane-associated zinc metalloprotease
A3P31_06245	ENOG4105KNE	Phosphatidate cytidylyltransferase
A3P31_06250	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3P31_06255	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A3P31_06260	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3P31_06265	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A3P31_06270	ENOG4105CE9	30S ribosomal protein S2
A3P31_06275	ENOG41060K3	Methyltransferase
A3P31_06280	ENOG4105F6E	Acyl-transferase
A3P31_06290	ENOG4105BZ1	(ABC) transporter
A3P31_06295	ENOG4105BZ1	(ABC) transporter
A3P31_06300	ENOG4105VXM	UPF0154 protein
A3P31_06305	ENOG41086B1	Bacterial protein of unknown function (DUF896)
A3P31_06310	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3P31_06320	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A3P31_06330	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A3P31_06335	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A3P31_06340	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A3P31_06345	ENOG4105K5M	30s ribosomal protein S16
A3P31_06350	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3P31_06360	ENOG4105DZW	Dipeptidase
A3P31_06365	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A3P31_06370	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3P31_06375	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A3P31_06390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3P31_06395	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3P31_06400	ENOG4108JQ7	(ABC) transporter
A3P31_06410	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A3P31_06415	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A3P31_06420	ENOG4105CB5	ATP-dependent DNA helicase recG
A3P31_06425	ENOG4105DP4	dak2 domain fusion protein ylov
A3P31_06435	ENOG4105VB9	50S ribosomal protein l28
A3P31_06440	ENOG4105FJ0	thiamine
A3P31_06445	ENOG4105DJV	ribulose-phosphate 3-epimerase
A3P31_06450	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A3P31_06455	ENOG4105D9P	serine threonine protein kinase
A3P31_06460	ENOG4108ZF3	Phosphatase
A3P31_06465	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3P31_06470	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A3P31_06475	ENOG4105C25	Primosomal protein n'
A3P31_06480	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A3P31_06485	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A3P31_06500	ENOG4105DQ6	Transposase
A3P31_06505	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A3P31_06510	ENOG4105DX0	Hemolysin A
A3P31_06520	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A3P31_06525	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A3P31_06530	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A3P31_06535	ENOG4105M7K	Involved in the transcription termination process (By similarity)
A3P31_06545	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A3P31_06550	ENOG4105DC7	peptidase M24
A3P31_06555	ENOG4105K46	50S ribosomal protein l27
A3P31_06560	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A3P31_06565	ENOG41080E8	Transcriptional regulator, Spx MgsR family
A3P31_06590	ENOG41069HH	4-oxalocrotonate tautomerase
A3P31_06610	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
A3P31_06645	ENOG4105CK1	PTS System
A3P31_06650	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3P31_06655	ENOG4105CS2	ec 3.2.1.21
A3P31_06685	ENOG4105CTZ	aminopeptidase c
A3P31_06740	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3P31_06755	ENOG4108K4B	hydrolase
A3P31_06760	ENOG4105CD8	aminopeptidase N
A3P31_06765	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
A3P31_06770	ENOG4105US7	Histidine kinase
A3P31_06775	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A3P31_06795	ENOG4105E90	ABC transporter
A3P31_06800	ENOG4108IJ8	ABC transporter
A3P31_06805	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A3P31_06815	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3P31_06830	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3P31_06845	ENOG4105CK1	PTS System
A3P31_06860	ENOG4107R7I	amino acid
A3P31_06865	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3P31_06870	ENOG4105C37	(CBS) domain
A3P31_06895	ENOG4105D7V	transposase
A3P31_06925	ENOG4105BZ1	(ABC) transporter
A3P31_06940	ENOG4108TZY	GntR Family Transcriptional Regulator
A3P31_06950	ENOG4105E66	phosphoriboisomerase A
A3P31_06960	ENOG4105HUF	DNA protection during starvation protein
A3P31_06965	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A3P31_06975	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A3P31_06980	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A3P31_06985	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A3P31_06990	ENOG4105E2Z	phosphate ABC transporter (Permease
A3P31_06995	ENOG4105C8U	phosphate abc transporter
A3P31_07000	ENOG4105CVA	phosphate
A3P31_07010	ENOG4105CDA	abc transporter atp-binding protein
A3P31_07015	ENOG4105E5Q	amino acid AbC transporter
A3P31_07035	ENOG4105D5G	Transposase
A3P31_07045	ENOG4105DBI	uridine monophosphokinase
A3P31_07065	ENOG4105DRP	amino acid AbC transporter
A3P31_07070	ENOG4105EAD	ABC transporter
A3P31_07075	ENOG4105CT1	(ABC) transporter
A3P31_07085	ENOG4105CT1	(ABC) transporter
A3P31_07090	ENOG4105BZ1	(ABC) transporter
A3P31_07095	ENOG4105BZ1	(ABC) transporter
A3P31_07110	ENOG4107RGD	Major Facilitator superfamily
A3P31_07120	ENOG4105DUX	Transporter
A3P31_07135	ENOG4105C4B	ABC transporter, permease
A3P31_07140	ENOG41083J0	(ABC) transporter
A3P31_07205	ENOG4105E98	transcriptional regulator DeoR family
A3P31_07220	ENOG4108HCJ	Hydrolase
A3P31_07280	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A3P31_07295	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3P31_07320	ENOG4105D7V	transposase
A3P31_07335	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3P31_07345	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A3P31_07360	ENOG4105D2N	Aldolase
A3P31_07365	ENOG4105C75	arginyL-tRNA synthetase
A3P31_07375	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3P31_07395	ENOG4105C8T	Leucyl-tRNA synthetase
A3P31_07410	ENOG4105DQ6	Transposase
A3P31_07495	ENOG4105DQ6	Transposase
A3P31_07500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A3P31_07505	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A3P31_07550	ENOG4105CAY	ferredoxin--nadp reductase
A3P31_07555	ENOG4105DQR	SNARE associated Golgi
A3P31_07565	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A3P31_07575	ENOG4107R8B	5'-nucleotidase
A3P31_07585	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A3P31_07605	ENOG4105DC7	peptidase M24
A3P31_07620	ENOG4105D8X	mechanosensitive ion channel
A3P31_07625	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A3P31_07630	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A3P31_07635	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A3P31_07645	ENOG4105K63	Thioredoxin
A3P31_07650	ENOG4105C98	muts2 protein
A3P31_07660	ENOG4105VPH	UPF0473 protein
A3P31_07665	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A3P31_07670	ENOG4105VBH	UPF0297 protein
A3P31_07675	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3P31_07680	ENOG4105C1J	atp-dependent rna helicase
A3P31_07685	ENOG4105SFS	phosphoesterase RecJ domain protein
A3P31_07690	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A3P31_07695	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A3P31_07700	ENOG4105VIE	preprotein translocase, subunit YajC
A3P31_07705	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3P31_07710	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A3P31_07715	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A3P31_07720	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A3P31_07745	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A3P31_07750	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A3P31_07770	ENOG4108URH	decarboxylase
A3P31_07775	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A3P31_07780	ENOG4105C5H	ABC transporter
A3P31_07790	ENOG4105C5Y	PTS System
A3P31_07795	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A3P31_07810	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A3P31_07815	ENOG4105C83	adenylosuccinate lyase
A3P31_07820	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A3P31_07825	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
A3P31_07845	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3P31_07855	ENOG41072GX	Peptidase M22 Glycoprotease
A3P31_07860	ENOG4105X71	Membrane
A3P31_07875	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
A3P31_07885	ENOG4105X0R	protein from nitrogen regulatory protein P-II
A3P31_07890	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3P31_07900	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A3P31_07905	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A3P31_07910	ENOG4105C6E	dna polymerase iii
A3P31_07920	ENOG4108Z6B	deaminase
A3P31_07940	ENOG4107Y49	methyltransferase
A3P31_07955	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A3P31_07960	ENOG4108VZM	50s ribosomal protein L10
A3P31_07965	ENOG4106TNF	Periplasmic binding protein
A3P31_07970	ENOG4105CDA	abc transporter atp-binding protein
A3P31_07975	ENOG4105E5Q	amino acid AbC transporter
A3P31_07980	ENOG4105D7V	transposase
A3P31_07985	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3P31_07990	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3P31_07995	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A3P31_08005	ENOG4107FTN	50S ribosomal protein L33
A3P31_08010	ENOG4105EAH	synthase
A3P31_08020	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A3P31_08025	ENOG4105CMG	Carbohydrate kinase
A3P31_08040	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A3P31_08045	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A3P31_08050	ENOG4105C8N	cysteinyl-tRNA synthetase
A3P31_08055	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A3P31_08065	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A3P31_08075	ENOG4105CTZ	aminopeptidase c
A3P31_08100	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3P31_08115	ENOG4105PGM	cation diffusion facilitator family transporter
A3P31_08120	ENOG41080HT	Transcriptional regulator, arsr family
A3P31_08145	ENOG4105D85	methylase
A3P31_08180	ENOG4105VTR	Integrase
A3P31_08185	ENOG4108UJD	30S ribosomal protein S9
A3P31_08190	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3P31_08195	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3P31_08200	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A3P31_08205	ENOG4105D7V	transposase
A3P31_08210	ENOG4108JJB	ABC transporter
A3P31_08215	ENOG4108JJB	ABC transporter
A3P31_08220	ENOG4108ZT0	50S ribosomal protein l17
A3P31_08225	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3P31_08230	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3P31_08235	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3P31_08240	ENOG41067V7	50S ribosomal protein L36
A3P31_08245	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A3P31_08250	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A3P31_08255	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A3P31_08260	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3P31_08265	ENOG4105VPB	50S ribosomal protein L30
A3P31_08270	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3P31_08275	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A3P31_08280	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A3P31_08285	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3P31_08290	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A3P31_08295	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3P31_08300	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3P31_08305	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3P31_08310	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3P31_08315	ENOG41082SA	50s ribosomal protein l29
A3P31_08320	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A3P31_08325	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3P31_08330	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A3P31_08335	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3P31_08340	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3P31_08345	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3P31_08350	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A3P31_08355	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3P31_08360	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3P31_08365	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3P31_08370	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3P31_08375	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A3P31_08385	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3P31_08390	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3P31_08395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A3P31_08410	ENOG4105CRK	lysyL-tRNA synthetase
A3P31_08415	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A3P31_08420	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A3P31_08435	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A3P31_08440	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3P31_08450	ENOG41082I2	s4 domain protein
A3P31_08455	ENOG4108JA2	transcriptioN-repair coupling factor
A3P31_08460	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A3P31_08465	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A3P31_08475	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A3P31_08480	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A3P31_08485	ENOG4105C1J	atp-dependent rna helicase
A3P31_08490	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
A3P31_08495	ENOG41082DI	50s ribosomal protein l31
A3P31_08500	ENOG4107QTZ	amino acid
A3P31_08510	ENOG4105C7J	ABC transporter, permease
A3P31_08520	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A3P31_08525	ENOG4107RK0	Sucrose phosphorylase
A3P31_08530	ENOG4105DME	alpha-galactosidase
A3P31_08535	ENOG4107RBJ	symporter
A3P31_08540	ENOG4108R6W	Transcriptional regulator, ARAC family
A3P31_08545	ENOG4105DZW	Dipeptidase
A3P31_08550	ENOG4108DBC	nitroreductase
A3P31_08560	ENOG4105KVH	Transcriptional regulator
A3P31_08590	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A3P31_08635	ENOG4105CIG	ABC transporter
A3P31_08655	ENOG4108R6G	acetyltransferase
A3P31_08675	ENOG4105KIS	phospholipid-binding protein
A3P31_08690	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3P31_08700	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
A3P31_08710	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A3P31_08715	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3P31_08720	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
A3P31_08730	ENOG4105DCI	Phosphohydrolase
A3P31_08735	ENOG4105CG3	alpha amylase, catalytic region
A3P31_08740	ENOG4105EG2	ABC transporter, permease
A3P31_08745	ENOG4105D56	permease protein
A3P31_08750	ENOG4105XN3	extracellular solute-binding protein family 1
A3P31_08755	ENOG4108IJ9	(ABC) transporter
A3P31_08760	ENOG4107URF	beta-phospho-glucomutase
A3P31_08770	ENOG4108IUK	alpha amylase, catalytic
A3P31_08775	ENOG4105CG3	alpha amylase, catalytic region
A3P31_08780	ENOG4105FKQ	transcriptional regulator
A3P31_08785	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3P31_08790	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A3P31_08795	ENOG4105DFT	pur operon repressor
A3P31_08800	ENOG4105W42	Veg protein
A3P31_08805	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3P31_08815	ENOG4105F8V	Hydrolase, tatD family
A3P31_08820	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3P31_08825	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A3P31_08835	ENOG4108UK2	deaminase
A3P31_08860	ENOG41066F8	ROK family
A3P31_08865	ENOG4105CS2	ec 3.2.1.21
A3P31_08870	ENOG4105CK1	PTS System
A3P31_08875	ENOG4105VZJ	PTS System
A3P31_08885	ENOG4105VCP	PTS System
A3P31_08890	ENOG4108TZY	GntR Family Transcriptional Regulator
A3P31_08895	ENOG4105CS2	ec 3.2.1.21
A3P31_08905	ENOG4108S3Y	transcriptional regulator
A3P31_08910	ENOG4105CK1	PTS System
A3P31_08920	ENOG4105CS2	ec 3.2.1.21
A3P31_08935	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A3P31_08955	ENOG4108JQ7	(ABC) transporter
A3P31_08965	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3P31_08970	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3P31_08980	ENOG4108J59	Extracellular solute-binding protein, family 5
A3P31_08985	ENOG4105D5G	Transposase
A3P31_08995	ENOG4105CTZ	aminopeptidase c
A3P31_09005	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A3P31_09010	ENOG4107UZV	polysaccharide biosynthesis
A3P31_09015	ENOG4108Y1J	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A3P31_09020	ENOG4108KGH	TRANSCRIPTIONal
A3P31_09030	ENOG4105CSC	Glucose uptake protein
A3P31_09045	ENOG4105CKK	Glycosyl transferase, family 2
A3P31_09055	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A3P31_09080	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
A3P31_09085	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3P31_09105	ENOG4105EE0	oxidoreductase
A3P31_09160	ENOG4105DQ6	Transposase
A3P31_09170	ENOG4105DFH	Transport of potassium into the cell (By similarity)
A3P31_09175	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A3P31_09185	ENOG4105C9K	Endothelin-converting enzyme 1
A3P31_09190	ENOG4105DM4	PTS System
A3P31_09195	ENOG4105DE4	1-phosphofructokinase
A3P31_09210	ENOG4105D2M	Aldolase
A3P31_09215	ENOG410605W	Major Facilitator
A3P31_09225	ENOG4105VG1	fes assembly suf system protein
A3P31_09230	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
A3P31_09235	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
A3P31_09245	ENOG4105CAQ	asparagine synthetase
A3P31_09260	ENOG4105S7S	phosphonate abc transporter
A3P31_09270	ENOG4105D5T	phosphonate abc transporter
A3P31_09280	ENOG4107YZX	Universal stress protein
A3P31_09285	ENOG4105M2Z	protein tyrosine serine phosphatase
A3P31_09290	ENOG4105FDP	GntR family transcriptional regulator
A3P31_09300	ENOG4106D5D	Nucleoside deoxyribosyltransferase
A3P31_09315	ENOG4105EXC	Acyl-transferase
A3P31_09335	ENOG4108EQA	pts system
A3P31_09340	ENOG4105F3R	pts system mannose fructose sorbose family iid
A3P31_09345	ENOG4105ETZ	PTS System
A3P31_09350	ENOG4108IQ3	PTS system
A3P31_09355	ENOG4105CE4	GlcNAc 6-P deacetylase
A3P31_09360	ENOG4105E70	isomerase
A3P31_09365	ENOG4105FDP	GntR family transcriptional regulator
A3P31_09390	ENOG4105EEQ	Na H antiporter
A3P31_09400	ENOG4105CPF	Cell wall formation (By similarity)
A3P31_09425	ENOG4105UQX	Mate efflux family protein
A3P31_09450	ENOG4105C85	amino acid
A3P31_09465	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3P31_09480	ENOG4105K64	Glycosyl transferase, family 2
A3P31_09490	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3P31_09505	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A3P31_09515	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3P31_09520	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A3P31_09525	ENOG4107TS3	membrane protein, TerC
A3P31_09530	ENOG4105K78	MarR family Transcriptional regulator
A3P31_09535	ENOG4108VX5	3-methyladenine DNA glycosylase
A3P31_09540	ENOG4105E5Q	amino acid AbC transporter
A3P31_09545	ENOG4105CDA	abc transporter atp-binding protein
A3P31_09570	ENOG4107R8N	Glycosyl transferase, family 2
A3P31_09590	ENOG4105F4P	)-transporter
A3P31_09595	ENOG4108V0P	LemA family
A3P31_09600	ENOG4105D0M	Protease HtpX homolog
A3P31_09615	ENOG4108JJB	ABC transporter
A3P31_09625	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A3P31_09630	ENOG4105C0H	protease
A3P31_09635	ENOG4105Q2H	domain protein
A3P31_09650	ENOG4105BZU	Histidine kinase
A3P31_09655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A3P31_09690	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
A3P31_09695	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3P31_09700	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A3P31_09710	ENOG4105C5Q	Transcriptional regulator
A3P31_09725	ENOG4105C5I	Dehydrogenase
A3P31_09735	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3P31_09740	ENOG4105DC8	reductase
A3P31_09745	ENOG4106F5Q	Membrane
A3P31_09765	ENOG4105CGK	Exodeoxyribonuclease III
A3P31_09770	ENOG4107BMA	Transglycosylase associated protein
A3P31_09830	ENOG4105NA0	Transcriptional regulator
A3P31_09860	ENOG4105BZ1	(ABC) transporter
A3P31_09870	ENOG4108S8M	degv family