locus-tag	class	description
A3P31_00020	COG1192	Involved in chromosome partitioning
A3P31_00045	COG0582	viral genome integration into host DNA
A3P31_00050	COG0629	single-stranded DNA binding
A3P31_00095	COG1192	Involved in chromosome partitioning
A3P31_00120	COG0582	viral genome integration into host DNA
A3P31_00125	COG0629	single-stranded DNA binding
A3P31_00270	COG4372	Transposase
A3P31_00540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3P31_00580	COG0305	Participates in initiation and elongation during chromosome replication
A3P31_00585	COG0359	binds to the 23S rRNA
A3P31_00600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A3P31_00605	COG0629	single-stranded DNA binding
A3P31_00610	COG0360	Binds together with S18 to 16S ribosomal RNA
A3P31_00615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3P31_00620	COG0187	DNA topoisomerase II activity
A3P31_00625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3P31_00635	COG0592	DNA-directed DNA polymerase activity
A3P31_00640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A3P31_00645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A3P31_00650	COG0594	ribonuclease P activity
A3P31_00655	COG0706	membrane insertase activity
A3P31_00660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A3P31_00665	COG0445	tRNA wobble uridine modification
A3P31_00670	COG0028	Belongs to the TPP enzyme family
A3P31_00675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3P31_00685	COG1193	negative regulation of DNA recombination
A3P31_00700	COG0477	Major facilitator Superfamily
A3P31_00715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A3P31_00725	COG0531	amino acid
A3P31_00730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A3P31_00745	COG2217	Heavy metal translocating P-type atpase
A3P31_00775	COG0242	peptide deformylase activity
A3P31_00790	COG2252	PERMEase
A3P31_00800	COG2252	PERMEase
A3P31_00810	COG2252	PERMEase
A3P31_00815	COG1304	FMN binding
A3P31_00820	COG1428	Deoxynucleoside kinase
A3P31_00825	COG1428	Deoxynucleoside kinase
A3P31_00830	COG0363	glucosamine-6-phosphate deaminase activity
A3P31_00835	COG0656	L-ascorbic acid biosynthetic process
A3P31_00855	COG4948	Mandelate Racemase Muconate Lactonizing
A3P31_00875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_00880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3P31_00885	COG1744	ABC transporter substrate-binding protein PnrA-like
A3P31_00905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3P31_00910	COG4988	ABC transporter
A3P31_00915	COG1294	oxidase, subunit
A3P31_00920	COG1271	oxidase subunit
A3P31_00925	COG0577	efflux transmembrane transporter activity
A3P31_00925	COG1136	(ABC) transporter
A3P31_00925	COG0577	efflux transmembrane transporter activity
A3P31_00925	COG1136	(ABC) transporter
A3P31_00945	COG3775	system Galactitol-specific IIC component
A3P31_01010	COG2274	protein secretion by the type I secretion system
A3P31_01025	COG0517	IMP dehydrogenase activity
A3P31_01060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3P31_01065	COG1696	Membrane protein involved in D-alanine export
A3P31_01070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3P31_01075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A3P31_01085	COG2814	Major facilitator Superfamily
A3P31_01095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_01095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_01105	COG0542	response to heat
A3P31_01110	COG0531	amino acid
A3P31_01210	COG3715	PTS system
A3P31_01215	COG3716	PTS system mannose fructose sorbose family IID component
A3P31_01225	COG1113	amino acid transport
A3P31_01230	COG1113	amino acid transport
A3P31_01235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3P31_01245	COG2502	aspartate--ammonia ligase
A3P31_01255	COG0531	amino acid
A3P31_01260	COG3442	glutamine amidotransferase
A3P31_01265	COG0351	phosphomethylpyrimidine kinase
A3P31_01270	COG2365	Tyrosine phosphatase family
A3P31_01285	COG1263	PTS System
A3P31_01285	COG2190	(PTS) system
A3P31_01285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_01295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3P31_01305	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3P31_01320	COG0710	3-dehydroquinate dehydratase activity
A3P31_01325	COG3104	oligopeptide transport
A3P31_01340	COG0584	glycerophosphoryl diester phosphodiesterase
A3P31_01360	COG3022	response to hydroperoxide
A3P31_01370	COG0588	phosphoglycerate mutase activity
A3P31_01375	COG0588	phosphoglycerate mutase activity
A3P31_01390	COG1136	(ABC) transporter
A3P31_01420	COG0431	NADPH-dependent FMN reductase
A3P31_01425	COG0431	NADPH-dependent FMN reductase
A3P31_01450	COG0357	Ribosomal RNA small subunit methyltransferase G
A3P31_01460	COG1192	Involved in chromosome partitioning
A3P31_01465	COG1475	DNA binding
A3P31_01470	COG4481	Protein conserved in bacteria
A3P31_01475	COG0012	GTP binding
A3P31_01485	COG1132	(ABC) transporter
A3P31_01490	COG1132	(ABC) transporter
A3P31_01500	COG5002	protein histidine kinase activity
A3P31_01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A3P31_01510	COG1794	racemase activity, acting on amino acids and derivatives
A3P31_01515	COG4152	abc transporter atp-binding protein
A3P31_01520	COG1668	transmembrane transport
A3P31_01530	COG1349	DNA-binding transcription factor activity
A3P31_01535	COG1105	Belongs to the carbohydrate kinase PfkB family
A3P31_01540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3P31_01540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3P31_01540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3P31_01550	COG0561	phosphatase activity
A3P31_01555	COG0640	Transcriptional regulator
A3P31_01565	COG1121	(ABC) transporter
A3P31_01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3P31_01575	COG1620	l-lactate permease
A3P31_01585	COG1316	TRANSCRIPTIONal
A3P31_01600	COG0488	(ABC) transporter
A3P31_01605	COG2966	Psort location CytoplasmicMembrane, score
A3P31_01635	COG1780	Probably involved in ribonucleotide reductase function
A3P31_01655	COG0194	GDP metabolic process
A3P31_01680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3P31_01695	COG0531	amino acid
A3P31_01700	COG1136	(ABC) transporter
A3P31_01710	COG0588	phosphoglycerate mutase activity
A3P31_01730	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A3P31_01735	COG1737	Transcriptional regulator
A3P31_01760	COG3973	AAA domain
A3P31_01765	COG4990	cell redox homeostasis
A3P31_01770	COG0517	IMP dehydrogenase activity
A3P31_01770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3P31_01780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_01805	COG4372	Transposase
A3P31_01835	COG1072	(Pantothenic acid kinase))
A3P31_01840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A3P31_01845	COG3711	transcriptional antiterminator
A3P31_01850	COG1263	PTS System
A3P31_01850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_01850	COG2190	(PTS) system
A3P31_01870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_01870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3P31_01880	COG3716	PTS system mannose fructose sorbose family IID component
A3P31_01895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A3P31_01900	COG1823	symporter activity
A3P31_01910	COG1970	mechanosensitive ion channel activity
A3P31_01930	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3P31_01950	COG2176	DNA-directed DNA polymerase activity
A3P31_01975	COG3842	ATPase activity
A3P31_01980	COG1175	transmembrane transport
A3P31_02005	COG1846	Transcriptional regulator
A3P31_02020	COG2971	BadF BadG BcrA BcrD
A3P31_02035	COG1033	growth of symbiont in host cell
A3P31_02035	COG2409	Drug exporters of the RND superfamily
A3P31_02040	COG0561	phosphatase activity
A3P31_02055	COG1012	belongs to the aldehyde dehydrogenase family
A3P31_02075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3P31_02080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3P31_02245	COG0438	transferase activity, transferring glycosyl groups
A3P31_02250	COG0438	transferase activity, transferring glycosyl groups
A3P31_02260	COG1368	sulfuric ester hydrolase activity
A3P31_02380	COG1113	amino acid transport
A3P31_02385	COG1012	belongs to the aldehyde dehydrogenase family
A3P31_02385	COG1454	alcohol dehydrogenase
A3P31_02410	COG1205	dead DEAH box helicase
A3P31_02410	COG1111	helicase
A3P31_02415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3P31_02430	COG0656	L-ascorbic acid biosynthetic process
A3P31_02445	COG3223	Belongs to the PsiE family
A3P31_02475	COG0673	inositol 2-dehydrogenase activity
A3P31_02480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3P31_02535	COG1216	Glycosyl transferase, family 2
A3P31_02535	COG0463	Glycosyl transferase, family 2
A3P31_02540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3P31_02545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A3P31_02550	COG0464	growth
A3P31_02560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3P31_02585	COG4684	Psort location CytoplasmicMembrane, score
A3P31_02590	COG1705	Flagellar rod assembly protein muramidase FlgJ
A3P31_02600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3P31_02610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3P31_02615	COG0154	amidase activity
A3P31_02620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3P31_02625	COG1597	lipid kinase activity
A3P31_02635	COG0561	phosphatase activity
A3P31_02655	COG1122	ATPase activity
A3P31_02660	COG4720	Psort location CytoplasmicMembrane, score
A3P31_02685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3P31_02805	COG2217	Heavy metal translocating P-type atpase
A3P31_02815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3P31_02820	COG1573	uracil-dna glycosylase
A3P31_02850	COG0564	pseudouridine synthase activity
A3P31_02855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3P31_02860	COG3679	Belongs to the UPF0342 family
A3P31_02875	COG3481	metal-dependent phosphohydrolase, HD sub domain
A3P31_02880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A3P31_02895	COG0537	adenosine 5'-monophosphoramidase activity
A3P31_02900	COG1131	(ABC) transporter
A3P31_02910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A3P31_02920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3P31_02925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3P31_02930	COG3142	Participates in the control of copper homeostasis
A3P31_02935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A3P31_02955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3P31_02955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3P31_02960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A3P31_02965	COG0237	dephospho-CoA kinase activity
A3P31_02970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A3P31_02980	COG1484	DNA-dependent DNA replication
A3P31_02985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3P31_03000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A3P31_03010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A3P31_03020	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A3P31_03025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3P31_03030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A3P31_03035	COG1713	HD superfamily hydrolase involved in NAD metabolism
A3P31_03040	COG0799	negative regulation of ribosome biogenesis
A3P31_03045	COG1323	Belongs to the UPF0348 family
A3P31_03060	COG5002	protein histidine kinase activity
A3P31_03065	COG0706	membrane insertase activity
A3P31_03070	COG1254	Belongs to the acylphosphatase family
A3P31_03075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3P31_03080	COG1733	regulation of RNA biosynthetic process
A3P31_03085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3P31_03090	COG0072	phenylalanine-tRNA ligase activity
A3P31_03095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A3P31_03110	COG0768	penicillin binding
A3P31_03120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3P31_03145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A3P31_03155	COG2814	Major facilitator Superfamily
A3P31_03160	COG0561	phosphatase activity
A3P31_03185	COG3425	synthase
A3P31_03190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3P31_03195	COG2137	regulation of response to DNA damage stimulus
A3P31_03200	COG3557	Belongs to the UPF0374 family
A3P31_03215	COG1253	flavin adenine dinucleotide binding
A3P31_03220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A3P31_03230	COG0542	response to heat
A3P31_03240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3P31_03250	COG1393	Belongs to the ArsC family
A3P31_03270	COG4116	CYTH
A3P31_03275	COG2357	RelA SpoT domain protein
A3P31_03280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3P31_03285	COG0564	pseudouridine synthase activity
A3P31_03300	COG2706	6-phosphogluconolactonase activity
A3P31_03310	COG0628	permease
A3P31_03325	COG1280	lysine exporter protein (LysE YggA)
A3P31_03325	COG1674	ftsk spoiiie
A3P31_03335	COG0612	Peptidase, M16
A3P31_03340	COG1028	Short-chain dehydrogenase reductase Sdr
A3P31_03345	COG1426	Protein conserved in bacteria
A3P31_03350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3P31_03355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A3P31_03365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3P31_03370	COG1739	Uncharacterized protein family UPF0029
A3P31_03375	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A3P31_03390	COG0653	protein targeting
A3P31_03395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A3P31_03405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A3P31_03410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A3P31_03415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A3P31_03420	COG0492	ferredoxin-NADP+ reductase activity
A3P31_03445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3P31_03450	COG3250	beta-galactosidase activity
A3P31_03460	COG1609	Transcriptional regulator
A3P31_03480	COG2801	Transposase and inactivated derivatives
A3P31_03505	COG1874	Beta-galactosidase
A3P31_03515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3P31_03520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A3P31_03525	COG2017	converts alpha-aldose to the beta-anomer
A3P31_03530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3P31_03535	COG0556	nucleotide-excision repair
A3P31_03540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A3P31_03550	COG1660	Displays ATPase and GTPase activities
A3P31_03560	COG1481	regulation of sporulation
A3P31_03610	COG2390	Transcriptional regulator
A3P31_03620	COG0126	phosphoglycerate kinase activity
A3P31_03625	COG0149	triose-phosphate isomerase activity
A3P31_03630	COG0148	phosphopyruvate hydratase activity
A3P31_03640	COG0557	exoribonuclease II activity
A3P31_03645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A3P31_03665	COG0561	phosphatase activity
A3P31_03670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A3P31_03675	COG0280	phosphate acetyltransferase
A3P31_03680	COG0802	atpase or kinase
A3P31_03690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A3P31_03695	COG3842	ATPase activity
A3P31_03700	COG1176	ABC-type spermidine putrescine transport system, permease component I
A3P31_03705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3P31_03715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A3P31_03725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3P31_03730	COG0561	phosphatase activity
A3P31_03735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3P31_03740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3P31_03755	COG2267	carboxylic ester hydrolase activity
A3P31_03765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A3P31_03775	COG0217	transcriptional regulatory protein
A3P31_03780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A3P31_03790	COG4537	Required for transformation and DNA binding
A3P31_03810	COG0827	DNA restriction-modification system
A3P31_03815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3P31_03845	COG1482	cell wall glycoprotein biosynthetic process
A3P31_03855	COG0745	RESPONSE REGULATOR receiver
A3P31_03860	COG3850	Histidine kinase
A3P31_03860	COG5002	protein histidine kinase activity
A3P31_03865	COG1368	sulfuric ester hydrolase activity
A3P31_03875	COG0166	Belongs to the GPI family
A3P31_03900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3P31_03905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A3P31_03910	COG1435	thymidine kinase activity
A3P31_03915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A3P31_03920	COG2890	protein-(glutamine-N5) methyltransferase activity
A3P31_03925	COG0009	L-threonylcarbamoyladenylate synthase
A3P31_03935	COG0356	it plays a direct role in the translocation of protons across the membrane
A3P31_03940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3P31_03945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A3P31_03950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3P31_03960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A3P31_03965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A3P31_03970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A3P31_03980	COG1077	Cell shape determining protein MreB Mrl
A3P31_03990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A3P31_04000	COG0772	Belongs to the SEDS family
A3P31_04015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3P31_04030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A3P31_04035	COG1104	cysteine desulfurase activity
A3P31_04040	COG0301	tRNA thio-modification
A3P31_04045	COG1187	pseudouridine synthase activity
A3P31_04055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3P31_04060	COG0525	valine-tRNA ligase activity
A3P31_04070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3P31_04075	COG2003	Belongs to the UPF0758 family
A3P31_04080	COG1077	Cell shape determining protein MreB Mrl
A3P31_04105	COG2001	Belongs to the MraZ family
A3P31_04110	COG0275	rRNA processing
A3P31_04125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3P31_04130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3P31_04135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3P31_04140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A3P31_04150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3P31_04155	COG1799	cell septum assembly
A3P31_04170	COG3599	regulation of cell shape
A3P31_04175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A3P31_04180	COG1278	Cold shock
A3P31_04185	COG0494	nUDIX hydrolase
A3P31_04200	COG1104	cysteine desulfurase activity
A3P31_04210	COG0482	sulfurtransferase activity
A3P31_04225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3P31_04245	COG0242	peptide deformylase activity
A3P31_04260	COG0772	Belongs to the SEDS family
A3P31_04270	COG0742	ribosomal rna small subunit methyltransferase
A3P31_04275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A3P31_04280	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3P31_04285	COG1555	photosystem II stabilization
A3P31_04285	COG1596	polysaccharide export
A3P31_04295	COG1466	dna polymerase III delta subunit
A3P31_04300	COG0268	Binds directly to 16S ribosomal RNA
A3P31_04305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3P31_04320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3P31_04330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A3P31_04340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3P31_04355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3P31_04385	COG3944	biosynthesis protein
A3P31_04390	COG0489	protein tyrosine kinase activity
A3P31_04400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3P31_04405	COG0438	transferase activity, transferring glycosyl groups
A3P31_04415	COG1216	Glycosyl transferase, family 2
A3P31_04415	COG1442	glycosyl transferase family 8
A3P31_04430	COG0438	transferase activity, transferring glycosyl groups
A3P31_04440	COG0562	UDP-galactopyranose mutase
A3P31_04470	COG4372	Transposase
A3P31_04535	COG1213	nucleotidyl transferase
A3P31_04540	COG4750	Nucleotidyl transferase
A3P31_04545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A3P31_04580	COG1518	maintenance of DNA repeat elements
A3P31_04610	COG2801	Transposase and inactivated derivatives
A3P31_04630	COG0501	Belongs to the peptidase M48B family
A3P31_04650	COG1857	crispr-associated protein
A3P31_04665	COG1518	maintenance of DNA repeat elements
A3P31_04670	COG2176	DNA-directed DNA polymerase activity
A3P31_04725	COG0586	Pfam SNARE associated Golgi protein
A3P31_04730	COG1957	nucleoside hydrolase
A3P31_04735	COG0322	excinuclease ABC activity
A3P31_04740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3P31_04745	COG2755	lipolytic protein G-D-S-L family
A3P31_04745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3P31_04750	COG1234	tRNA 3'-trailer cleavage
A3P31_04755	COG0300	oxidoreductase activity
A3P31_04765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A3P31_04770	COG0737	Belongs to the 5'-nucleotidase family
A3P31_04780	COG0587	DNA-directed DNA polymerase activity
A3P31_04790	COG0205	6-phosphofructokinase activity
A3P31_04800	COG2996	Protein conserved in bacteria
A3P31_04810	COG0456	acetyltransferase
A3P31_04815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A3P31_04820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A3P31_04825	COG1187	pseudouridine synthase activity
A3P31_04835	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A3P31_04840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A3P31_04845	COG0539	negative regulation of cytoplasmic translation
A3P31_04850	COG1160	GTP binding
A3P31_04865	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A3P31_04880	COG0732	type I restriction modification DNA specificity domain
A3P31_04895	COG0494	nUDIX hydrolase
A3P31_04900	COG0513	Belongs to the DEAD box helicase family
A3P31_04910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3P31_04915	COG0617	tRNA 3'-terminal CCA addition
A3P31_04920	COG1272	protein, Hemolysin III
A3P31_04925	COG1307	EDD domain protein, DegV family
A3P31_04930	COG4479	Belongs to the UPF0346 family
A3P31_04935	COG0793	Belongs to the peptidase S41A family
A3P31_04935	COG3409	Peptidoglycan-binding domain 1 protein
A3P31_04940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3P31_04945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3P31_04950	COG0758	DNA mediated transformation
A3P31_04955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3P31_04960	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A3P31_04965	COG4974	Belongs to the 'phage' integrase family
A3P31_04975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A3P31_05005	COG2855	membrane
A3P31_05020	COG2801	Transposase and inactivated derivatives
A3P31_05030	COG0028	Belongs to the TPP enzyme family
A3P31_05035	COG3527	Alpha-acetolactate decarboxylase
A3P31_05045	COG0656	L-ascorbic acid biosynthetic process
A3P31_05050	COG1011	Hydrolase
A3P31_05055	COG1051	belongs to the nudix hydrolase family
A3P31_05085	COG1114	Component of the transport system for branched-chain amino acids
A3P31_05090	COG0396	ATPase activity
A3P31_05095	COG0719	Fe-S assembly protein
A3P31_05100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3P31_05110	COG0719	Fe-S assembly protein
A3P31_05130	COG2801	Transposase and inactivated derivatives
A3P31_05175	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A3P31_05205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3P31_05225	COG0110	maltose O-acetyltransferase activity
A3P31_05230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A3P31_05235	COG0187	DNA topoisomerase II activity
A3P31_05240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3P31_05250	COG1227	inorganic diphosphatase activity
A3P31_05255	COG0514	ATP-dependent DNA helicase (RecQ)
A3P31_05270	COG4974	Belongs to the 'phage' integrase family
A3P31_05275	COG0583	DNA-binding transcription factor activity
A3P31_05285	COG1307	EDD domain protein, DegV family
A3P31_05310	COG0564	pseudouridine synthase activity
A3P31_05315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A3P31_05320	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A3P31_05330	COG1307	EDD domain protein, DegV family
A3P31_05345	COG0116	Belongs to the methyltransferase superfamily
A3P31_05355	COG3599	regulation of cell shape
A3P31_05360	COG4474	Belongs to the UPF0398 family
A3P31_05365	COG3331	DNA recombination
A3P31_05375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3P31_05380	COG3935	DnaD domain protein
A3P31_05385	COG0017	Asparaginyl-tRNA synthetase
A3P31_05395	COG1199	ATP-dependent helicase activity
A3P31_05395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A3P31_05400	COG1074	ATP-dependent DNA helicase activity
A3P31_05405	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A3P31_05430	COG1132	(ABC) transporter
A3P31_05445	COG2801	Transposase and inactivated derivatives
A3P31_05470	COG4975	Glucose uptake
A3P31_05475	COG1869	D-ribose catabolic process
A3P31_05480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A3P31_05485	COG0406	alpha-ribazole phosphatase activity
A3P31_05500	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
A3P31_05525	COG0572	uridine kinase
A3P31_05565	COG2365	Tyrosine phosphatase family
A3P31_05610	COG1132	(ABC) transporter
A3P31_05625	COG1132	(ABC) transporter
A3P31_05650	COG1929	Belongs to the glycerate kinase type-1 family
A3P31_05665	COG1902	pentaerythritol trinitrate reductase activity
A3P31_05675	COG3590	peptidase
A3P31_05690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A3P31_05695	COG1335	isochorismatase
A3P31_05705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3P31_05710	COG0505	Belongs to the CarA family
A3P31_05715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3P31_05720	COG0540	Belongs to the ATCase OTCase family
A3P31_05730	COG0167	dihydroorotate dehydrogenase activity
A3P31_05735	COG0284	orotidine-5'-phosphate decarboxylase activity
A3P31_05740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3P31_05755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A3P31_05760	COG0393	Putative heavy-metal-binding
A3P31_05800	COG1131	(ABC) transporter
A3P31_05805	COG1725	Transcriptional regulator
A3P31_05810	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3P31_05815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3P31_05820	COG2384	SAM-dependent methyltransferase
A3P31_05830	COG1126	abc transporter atp-binding protein
A3P31_05835	COG0765	amino acid transport
A3P31_05840	COG0765	amino acid transport
A3P31_05845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A3P31_05850	COG0358	DNA primase activity
A3P31_05855	COG0751	glycine-tRNA ligase activity
A3P31_05860	COG0752	glycyl-tRNA synthetase alpha subunit
A3P31_05865	COG1381	Involved in DNA repair and RecF pathway recombination
A3P31_05870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A3P31_05875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A3P31_05880	COG1702	phosphate starvation-inducible protein PhoH
A3P31_05885	COG1610	YqeY-like protein
A3P31_05890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A3P31_05895	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A3P31_05900	COG2151	metal-sulfur cluster biosynthetic enzyme
A3P31_05905	COG1760	l-serine dehydratase
A3P31_05910	COG1760	l-serine dehydratase
A3P31_05915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3P31_05920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3P31_05940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3P31_05945	COG0436	Aminotransferase
A3P31_05950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A3P31_05955	COG0124	histidyl-tRNA synthetase
A3P31_05960	COG1490	D-aminoacyl-tRNA deacylase activity
A3P31_05965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3P31_05975	COG2264	protein methyltransferase activity
A3P31_05980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A3P31_05990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3P31_05995	COG0252	asparaginase activity
A3P31_06005	COG0039	L-malate dehydrogenase activity
A3P31_06010	COG1053	succinate dehydrogenase
A3P31_06015	COG0114	fumarate hydratase activity
A3P31_06020	COG2011	ABC-type metal ion transport system permease component
A3P31_06025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3P31_06030	COG1464	Belongs to the NlpA lipoprotein family
A3P31_06065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A3P31_06070	COG0488	(ABC) transporter
A3P31_06080	COG0148	phosphopyruvate hydratase activity
A3P31_06095	COG0583	DNA-binding transcription factor activity
A3P31_06100	COG2217	Heavy metal translocating P-type atpase
A3P31_06110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A3P31_06115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A3P31_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3P31_06125	COG0531	amino acid
A3P31_06130	COG2801	Transposase and inactivated derivatives
A3P31_06145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A3P31_06145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A3P31_06150	COG3764	Sortase (surface protein transpeptidase)
A3P31_06155	COG0481	GTPase activity
A3P31_06160	COG0484	heat shock protein binding
A3P31_06165	COG0443	Heat shock 70 kDa protein
A3P31_06170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3P31_06175	COG1420	regulation of RNA biosynthetic process
A3P31_06185	COG0488	(ABC) transporter
A3P31_06190	COG0196	riboflavin kinase activity
A3P31_06195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3P31_06200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A3P31_06205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3P31_06215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A3P31_06220	COG0195	Participates in both transcription termination and antitermination
A3P31_06225	COG0779	Required for maturation of 30S ribosomal subunits
A3P31_06235	COG0442	prolyl-tRNA aminoacylation
A3P31_06240	COG0750	zinc metalloprotease
A3P31_06245	COG4589	Belongs to the CDS family
A3P31_06250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3P31_06255	COG0233	cytoplasmic translational termination
A3P31_06260	COG0528	UMP kinase activity
A3P31_06265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A3P31_06270	COG0052	Belongs to the universal ribosomal protein uS2 family
A3P31_06275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A3P31_06280	COG0204	Acyl-transferase
A3P31_06285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3P31_06290	COG1132	(ABC) transporter
A3P31_06295	COG1132	(ABC) transporter
A3P31_06300	COG3763	UPF0154 protein
A3P31_06305	COG4224	UPF0291 protein
A3P31_06310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3P31_06320	COG0494	nUDIX hydrolase
A3P31_06335	COG0336	Belongs to the RNA methyltransferase TrmD family
A3P31_06340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A3P31_06350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3P31_06365	COG0552	protein localization to endoplasmic reticulum
A3P31_06370	COG1196	nuclear chromosome segregation
A3P31_06375	COG0571	ribonuclease III activity
A3P31_06390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3P31_06395	COG0601	transmembrane transport
A3P31_06400	COG4608	Belongs to the ABC transporter superfamily
A3P31_06410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3P31_06415	COG0416	fatty acid biosynthetic process
A3P31_06420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3P31_06425	COG1461	Dihydroxyacetone kinase
A3P31_06435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A3P31_06440	COG1564	THIamine pyrophosphokinase
A3P31_06445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A3P31_06450	COG1162	GTPase activity
A3P31_06455	COG0515	serine threonine protein kinase
A3P31_06455	COG2815	serine threonine protein kinase
A3P31_06460	COG0631	protein serine/threonine phosphatase activity
A3P31_06465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3P31_06465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3P31_06470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A3P31_06475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A3P31_06480	COG1758	RNA polymerase activity
A3P31_06485	COG0194	GDP metabolic process
A3P31_06500	COG2801	Transposase and inactivated derivatives
A3P31_06505	COG0497	DNA recombination
A3P31_06510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A3P31_06520	COG1722	exodeoxyribonuclease VII activity
A3P31_06525	COG1570	exodeoxyribonuclease VII activity
A3P31_06530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A3P31_06535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3P31_06545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A3P31_06550	COG0006	proline dipeptidase activity
A3P31_06555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A3P31_06560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A3P31_06565	COG1393	Belongs to the ArsC family
A3P31_06590	COG1942	4-Oxalocrotonate Tautomerase
A3P31_06645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_06655	COG2723	6-phospho-beta-galactosidase activity
A3P31_06685	COG3579	cysteine-type endopeptidase activity
A3P31_06710	COG2814	Major facilitator Superfamily
A3P31_06740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3P31_06755	COG0561	phosphatase activity
A3P31_06760	COG0308	aminopeptidase N
A3P31_06765	COG2936	dipeptidyl-peptidase activity
A3P31_06770	COG5002	protein histidine kinase activity
A3P31_06775	COG0745	RESPONSE REGULATOR receiver
A3P31_06780	COG2357	RelA SpoT domain protein
A3P31_06795	COG1174	glycine betaine transport
A3P31_06800	COG0517	IMP dehydrogenase activity
A3P31_06800	COG1125	glycine betaine transport
A3P31_06805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3P31_06815	COG0024	Methionine aminopeptidase
A3P31_06820	COG0716	FMN binding
A3P31_06830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A3P31_06845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_06860	COG0531	amino acid
A3P31_06870	COG1253	flavin adenine dinucleotide binding
A3P31_06925	COG1132	(ABC) transporter
A3P31_06940	COG2188	Transcriptional regulator
A3P31_06950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3P31_06960	COG0783	Belongs to the Dps family
A3P31_06965	COG1288	antiporter activity
A3P31_06975	COG0704	Plays a role in the regulation of phosphate uptake
A3P31_06980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3P31_06985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3P31_06990	COG0581	inorganic phosphate transmembrane transporter activity
A3P31_06995	COG0573	inorganic phosphate transmembrane transporter activity
A3P31_07000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A3P31_07010	COG1126	abc transporter atp-binding protein
A3P31_07015	COG0765	amino acid transport
A3P31_07045	COG0572	uridine kinase
A3P31_07065	COG0765	amino acid transport
A3P31_07070	COG0765	amino acid transport
A3P31_07075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3P31_07085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3P31_07090	COG1132	(ABC) transporter
A3P31_07095	COG1132	(ABC) transporter
A3P31_07110	COG2814	Major facilitator Superfamily
A3P31_07125	COG1874	Beta-galactosidase
A3P31_07135	COG0390	transport system, permease component
A3P31_07140	COG4619	ABC transporter
A3P31_07205	COG1349	DNA-binding transcription factor activity
A3P31_07220	COG0561	phosphatase activity
A3P31_07245	COG0456	acetyltransferase
A3P31_07260	COG3409	Peptidoglycan-binding domain 1 protein
A3P31_07270	COG2814	Major facilitator Superfamily
A3P31_07275	COG2814	Major facilitator Superfamily
A3P31_07280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3P31_07295	COG0519	Catalyzes the synthesis of GMP from XMP
A3P31_07310	COG1956	GAF domain-containing protein
A3P31_07345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A3P31_07365	COG0018	arginyl-trna synthetase
A3P31_07370	COG1686	Belongs to the peptidase S11 family
A3P31_07375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3P31_07390	COG2244	polysaccharide biosynthetic process
A3P31_07395	COG0495	leucyl-tRNA aminoacylation
A3P31_07410	COG2801	Transposase and inactivated derivatives
A3P31_07495	COG2801	Transposase and inactivated derivatives
A3P31_07500	COG0477	Major facilitator Superfamily
A3P31_07505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A3P31_07545	COG1098	S1 RNA binding domain
A3P31_07550	COG0492	ferredoxin-NADP+ reductase activity
A3P31_07555	COG0586	Pfam SNARE associated Golgi protein
A3P31_07565	COG0647	UMP catabolic process
A3P31_07575	COG0737	Belongs to the 5'-nucleotidase family
A3P31_07585	COG0584	glycerophosphoryl diester phosphodiesterase
A3P31_07605	COG0006	proline dipeptidase activity
A3P31_07620	COG0668	transmembrane transport
A3P31_07625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3P31_07630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3P31_07635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A3P31_07640	COG1719	4-vinyl reductase, 4VR
A3P31_07645	COG3118	belongs to the thioredoxin family
A3P31_07650	COG1193	negative regulation of DNA recombination
A3P31_07665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A3P31_07675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3P31_07680	COG0513	Belongs to the DEAD box helicase family
A3P31_07685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3P31_07690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3P31_07695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A3P31_07700	COG1862	Preprotein translocase
A3P31_07705	COG2255	four-way junction helicase activity
A3P31_07710	COG0632	four-way junction helicase activity
A3P31_07715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A3P31_07720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3P31_07745	COG0459	protein refolding
A3P31_07780	COG0488	(ABC) transporter
A3P31_07785	COG1621	beta-fructofuranosidase activity
A3P31_07790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_07790	COG2190	(PTS) system
A3P31_07790	COG1263	PTS System
A3P31_07810	COG0494	nUDIX hydrolase
A3P31_07815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3P31_07820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A3P31_07825	COG0516	GMP reductase activity
A3P31_07845	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3P31_07855	COG1214	PFAM Peptidase M22, glycoprotease
A3P31_07860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A3P31_07875	COG4467	Involved in initiation control of chromosome replication
A3P31_07885	COG3870	Protein conserved in bacteria
A3P31_07890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3P31_07900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A3P31_07905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A3P31_07910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3P31_07920	COG0590	tRNA wobble adenosine to inosine editing
A3P31_07940	COG2813	Specifically methylates the guanine in position
A3P31_07960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A3P31_07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3P31_07970	COG1126	abc transporter atp-binding protein
A3P31_07975	COG0765	amino acid transport
A3P31_07985	COG0081	regulation of translation
A3P31_07990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3P31_07995	COG0250	Participates in transcription elongation, termination and antitermination
A3P31_08010	COG0142	geranyltranstransferase activity
A3P31_08020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A3P31_08025	COG1070	Carbohydrate kinase
A3P31_08040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3P31_08045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A3P31_08050	COG0215	cysteine-tRNA ligase activity
A3P31_08055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3P31_08065	COG0756	dUTP diphosphatase activity
A3P31_08100	COG0588	phosphoglycerate mutase activity
A3P31_08120	COG0640	Transcriptional regulator
A3P31_08145	COG1002	Type II restriction enzyme, methylase subunits
A3P31_08180	COG0582	viral genome integration into host DNA
A3P31_08190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3P31_08195	COG0101	tRNA pseudouridine synthase activity
A3P31_08200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3P31_08210	COG1122	ATPase activity
A3P31_08215	COG1122	ATPase activity
A3P31_08220	COG0203	ribosomal protein L17
A3P31_08225	COG0202	RNA polymerase activity
A3P31_08250	COG0563	adenylate kinase activity
A3P31_08260	COG0200	Binds to the 23S rRNA
A3P31_08275	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3P31_08280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3P31_08285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3P31_08290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A3P31_08295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3P31_08300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3P31_08315	COG0255	Belongs to the universal ribosomal protein uL29 family
A3P31_08320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A3P31_08325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3P31_08340	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3P31_08345	COG0089	rRNA binding
A3P31_08350	COG0088	Forms part of the polypeptide exit tunnel
A3P31_08355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3P31_08365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3P31_08370	COG0049	tRNA binding
A3P31_08385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3P31_08395	COG0542	response to heat
A3P31_08410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A3P31_08415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A3P31_08420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A3P31_08435	COG0037	tRNA processing
A3P31_08440	COG1185	polyribonucleotide nucleotidyltransferase activity
A3P31_08450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A3P31_08455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3P31_08460	COG0193	aminoacyl-tRNA hydrolase activity
A3P31_08465	COG0039	L-malate dehydrogenase activity
A3P31_08480	COG0736	holo-[acyl-carrier-protein] synthase activity
A3P31_08490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A3P31_08495	COG0254	rRNA binding
A3P31_08500	COG0531	amino acid
A3P31_08510	COG4120	Belongs to the binding-protein-dependent transport system permease family
A3P31_08520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A3P31_08525	COG0366	Alpha amylase catalytic
A3P31_08530	COG3345	alpha-galactosidase
A3P31_08545	COG4690	dipeptidase activity
A3P31_08550	COG0778	Nitroreductase
A3P31_08560	COG1733	regulation of RNA biosynthetic process
A3P31_08590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3P31_08635	COG1131	(ABC) transporter
A3P31_08655	COG0456	acetyltransferase
A3P31_08675	COG1881	PFAM PEBP family protein
A3P31_08690	COG0519	Catalyzes the synthesis of GMP from XMP
A3P31_08700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3P31_08710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A3P31_08715	COG0504	CTP synthase activity
A3P31_08720	COG3343	RNA polymerase activity
A3P31_08730	COG1078	dGTPase activity
A3P31_08735	COG0366	Alpha amylase catalytic
A3P31_08740	COG3833	ABC-type maltose transport systems, permease component
A3P31_08745	COG1175	transmembrane transport
A3P31_08750	COG1653	transport
A3P31_08755	COG3842	ATPase activity
A3P31_08760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3P31_08775	COG0366	Alpha amylase catalytic
A3P31_08780	COG1609	Transcriptional regulator
A3P31_08785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3P31_08790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A3P31_08795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3P31_08800	COG4466	Protein conserved in bacteria
A3P31_08805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3P31_08815	COG0084	hydrolase, TatD family'
A3P31_08820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3P31_08820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3P31_08825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3P31_08835	COG2131	deaminase
A3P31_08860	COG1940	carbohydrate kinase activity
A3P31_08865	COG2723	6-phospho-beta-galactosidase activity
A3P31_08870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_08875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_08885	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3P31_08890	COG2188	Transcriptional regulator
A3P31_08895	COG2723	6-phospho-beta-galactosidase activity
A3P31_08905	COG2188	Transcriptional regulator
A3P31_08910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3P31_08920	COG2723	6-phospho-beta-galactosidase activity
A3P31_08935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A3P31_08950	COG1418	mRNA catabolic process
A3P31_08955	COG4608	Belongs to the ABC transporter superfamily
A3P31_08960	COG0444	Belongs to the ABC transporter superfamily
A3P31_08965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3P31_08970	COG0601	transmembrane transport
A3P31_08980	COG4166	transmembrane transport
A3P31_08995	COG3579	cysteine-type endopeptidase activity
A3P31_09005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A3P31_09010	COG1368	sulfuric ester hydrolase activity
A3P31_09015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A3P31_09020	COG1316	TRANSCRIPTIONal
A3P31_09030	COG4975	Glucose uptake
A3P31_09055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A3P31_09080	COG1598	PFAM Uncharacterised protein family UPF0150
A3P31_09085	COG0588	phosphoglycerate mutase activity
A3P31_09105	COG0673	inositol 2-dehydrogenase activity
A3P31_09110	COG0475	glutathione-regulated potassium exporter activity
A3P31_09110	COG0569	domain protein
A3P31_09125	COG1705	Flagellar rod assembly protein muramidase FlgJ
A3P31_09125	COG1388	LysM domain
A3P31_09160	COG2801	Transposase and inactivated derivatives
A3P31_09170	COG3158	transport of potassium into the cell
A3P31_09175	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A3P31_09185	COG3590	peptidase
A3P31_09190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3P31_09190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3P31_09190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3P31_09210	COG3684	Belongs to the aldolase LacD family
A3P31_09215	COG2814	Major facilitator Superfamily
A3P31_09225	COG2151	metal-sulfur cluster biosynthetic enzyme
A3P31_09230	COG0602	queuosine metabolic process
A3P31_09235	COG1328	CTP reductase activity
A3P31_09245	COG0367	asparagine synthase
A3P31_09260	COG3639	organic phosphonate transmembrane transporter activity
A3P31_09280	COG0589	response to stress
A3P31_09285	COG2365	Tyrosine phosphatase family
A3P31_09300	COG3613	nucleoside 2-deoxyribosyltransferase
A3P31_09315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3P31_09315	COG2755	lipolytic protein G-D-S-L family
A3P31_09335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3P31_09335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_09340	COG3716	PTS system mannose fructose sorbose family IID component
A3P31_09350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3P31_09360	COG2222	sugar isomerase
A3P31_09400	COG1181	Belongs to the D-alanine--D-alanine ligase family
A3P31_09425	COG0534	Mate efflux family protein
A3P31_09450	COG1113	amino acid transport
A3P31_09465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3P31_09475	COG2267	carboxylic ester hydrolase activity
A3P31_09480	COG1216	Glycosyl transferase, family 2
A3P31_09490	COG0328	RNA-DNA hybrid ribonuclease activity
A3P31_09500	COG2738	Putative neutral zinc metallopeptidase
A3P31_09505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3P31_09515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3P31_09520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3P31_09525	COG0861	Integral membrane protein TerC family
A3P31_09530	COG3189	MarR family transcriptional regulator
A3P31_09535	COG2094	Belongs to the DNA glycosylase MPG family
A3P31_09540	COG0765	amino acid transport
A3P31_09545	COG1126	abc transporter atp-binding protein
A3P31_09570	COG1215	transferase activity, transferring glycosyl groups
A3P31_09590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3P31_09595	COG1704	LemA family
A3P31_09600	COG0501	Belongs to the peptidase M48B family
A3P31_09615	COG1122	ATPase activity
A3P31_09625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A3P31_09630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3P31_09635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3P31_09650	COG5002	protein histidine kinase activity
A3P31_09655	COG0745	RESPONSE REGULATOR receiver
A3P31_09690	COG2267	carboxylic ester hydrolase activity
A3P31_09695	COG2226	methyltransferase
A3P31_09700	COG1114	Component of the transport system for branched-chain amino acids
A3P31_09705	COG1053	succinate dehydrogenase
A3P31_09705	COG3976	FMN-binding domain protein
A3P31_09725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3P31_09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3P31_09745	COG0628	permease
A3P31_09765	COG0708	Exodeoxyribonuclease III
A3P31_09770	COG2261	transglycosylase associated protein
A3P31_09825	COG2217	Heavy metal translocating P-type atpase
A3P31_09870	COG1307	EDD domain protein, DegV family
A3P31_09875	COG1011	Hydrolase