locus-tag	class	description
SN35N_0004	ENOG4107QN2	dihydrolipoyl dehydrogenase
SN35N_0005	ENOG4105K56	Transcriptional regulator
SN35N_0008	ENOG4107RZX	Teichoic acid biosynthesis protein
SN35N_0010	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
SN35N_0012	ENOG4105DAA	L-lactate
SN35N_0015	ENOG4105C85	amino acid
SN35N_0026	ENOG4105EPR	degv family
SN35N_0028	ENOG4105F23	Fibronectin-binding protein
SN35N_0029	ENOG4108TU7	Inherit from COG: (ABC) transporter
SN35N_0030	ENOG4105CJ1	ABC, transporter
SN35N_0036	ENOG4108ZMX	Domain of unknown function (DU1801)
SN35N_0038	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SN35N_0039	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SN35N_0040	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
SN35N_0041	ENOG4105C34	Pseudouridine synthase
SN35N_0042	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SN35N_0043	ENOG4105CKU	formyltetrahydrofolate synthetase
SN35N_0046	ENOG4107VFR	oxidoreductase
SN35N_0053	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
SN35N_0060	ENOG4108MXZ	Esterase
SN35N_0063	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
SN35N_0064	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
SN35N_0065	ENOG4108UKS	UPF0398 protein
SN35N_0066	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
SN35N_0069	ENOG4107QKW	extracellular solute-binding protein family 1
SN35N_0071	ENOG4105D38	putrescine abc transporter
SN35N_0074	ENOG4108UMI	ABC transporter, permease
SN35N_0075	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SN35N_0077	ENOG4105C5S	asparaginyl-tRNA synthetase
SN35N_0080	ENOG4105DVT	helicase
SN35N_0085	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
SN35N_0086	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
SN35N_0087	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
SN35N_0091	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SN35N_0092	ENOG4108KP7	hydrolase
SN35N_0093	ENOG4105CUB	amino acid
SN35N_0094	ENOG4108JPW	Aminotransferase
SN35N_0100	ENOG41069HH	4-oxalocrotonate tautomerase
SN35N_0101	ENOG4105DZW	Dipeptidase
SN35N_0103	ENOG4106EMP	CsbD-like
SN35N_0105	ENOG4105DQ6	Transposase
SN35N_0106	ENOG4107BMA	Transglycosylase associated protein
SN35N_0109	ENOG4105CBD	Diacylglycerol kinase
SN35N_0110	ENOG4105KAF	membrAne
SN35N_0112	ENOG4105KAV	tspo and mbr like protein
SN35N_0115	ENOG4108M1A	Chitin-binding protein
SN35N_0119	ENOG4105D5G	Transposase
SN35N_0126	ENOG4105C57	major facilitator superfamily
SN35N_0128	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
SN35N_0129	ENOG4108S4H	thioesterase Superfamily protein
SN35N_0130	ENOG4105DUM	transcriptional regulator, lysR family
SN35N_0131	ENOG4108UQV	Membrane
SN35N_0133	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
SN35N_0136	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SN35N_0137	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SN35N_0139	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SN35N_0140	ENOG4105CHR	reductase
SN35N_0141	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SN35N_0142	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SN35N_0143	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SN35N_0144	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SN35N_0146	ENOG4105E1F	short-chain dehydrogenase reductase
SN35N_0148	ENOG4105CPQ	Dehydrogenase
SN35N_0149	ENOG4105CH2	amidohydrolase
SN35N_0154	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SN35N_0155	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SN35N_0156	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SN35N_0157	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SN35N_0158	ENOG4108I0Q	anthranilate phosphoribosyltransferase
SN35N_0159	ENOG4105DDQ	anthranilate synthase
SN35N_0166	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SN35N_0167	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SN35N_0168	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SN35N_0169	ENOG4105VB6	UPF0109 protein
SN35N_0170	ENOG4105K5M	30s ribosomal protein S16
SN35N_0171	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SN35N_0172	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
SN35N_0173	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SN35N_0174	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
SN35N_0175	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SN35N_0176	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SN35N_0177	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
SN35N_0178	ENOG4105CB5	ATP-dependent DNA helicase recG
SN35N_0179	ENOG4105DP4	dak2 domain fusion protein ylov
SN35N_0180	ENOG4108ZAA	Alkaline-shock protein
SN35N_0181	ENOG4105VB9	50S ribosomal protein l28
SN35N_0182	ENOG4105FJ0	thiamine
SN35N_0183	ENOG4105DJV	ribulose-phosphate 3-epimerase
SN35N_0184	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
SN35N_0185	ENOG4105D9P	serine threonine protein kinase
SN35N_0186	ENOG4108ZF3	Phosphatase
SN35N_0187	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SN35N_0188	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SN35N_0189	ENOG4105C25	Primosomal protein n'
SN35N_0190	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
SN35N_0191	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SN35N_0192	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SN35N_0194	ENOG4105R40	Glycine betaine carnitine choline
SN35N_0195	ENOG4108HQR	Glycine betaine
SN35N_0198	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SN35N_0199	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
SN35N_0200	ENOG4105DX0	Hemolysin A
SN35N_0201	ENOG4105CTB	Polyprenyl synthetase
SN35N_0202	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SN35N_0203	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SN35N_0204	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SN35N_0205	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SN35N_0206	ENOG4108ZSR	alkaline shock protein
SN35N_0207	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SN35N_0208	ENOG4105DC7	peptidase M24
SN35N_0209	ENOG4105K46	50S ribosomal protein l27
SN35N_0211	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
SN35N_0220	ENOG4105C5F	glutamine synthetase
SN35N_0221	ENOG4105KV4	Transcriptional regulator
SN35N_0222	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SN35N_0223	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
SN35N_0227	ENOG4105DKQ	ROK family
SN35N_0229	ENOG4107ZXI	Rhomboid family
SN35N_0230	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
SN35N_0231	ENOG4105WDJ	50S ribosomal protein L33
SN35N_0232	ENOG4107RF6	penicillin-binding protein
SN35N_0234	ENOG4105W8X	HesB YadR YfhF-family protein
SN35N_0237	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SN35N_0238	ENOG4105DBI	uridine monophosphokinase
SN35N_0240	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SN35N_0241	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SN35N_0244	ENOG4108RWN	rrna methyltransferase
SN35N_0245	ENOG410855V	Acylphosphatase
SN35N_0246	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
SN35N_0249	ENOG4105EYH	Exonuclease
SN35N_0251	ENOG4105GR3	Histidine kinase
SN35N_0252	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SN35N_0253	ENOG4105D1H	recombination factor protein RarA
SN35N_0254	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
SN35N_0257	ENOG41067VY	50S ribosomal protein L32
SN35N_0259	ENOG4105CDE	UPF0348 protein
SN35N_0260	ENOG4105DXX	methyltransferase
SN35N_0261	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
SN35N_0262	ENOG4108WF2	Metal Dependent Phosphohydrolase
SN35N_0263	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
SN35N_0264	ENOG410812S	Rna-binding protein
SN35N_0265	ENOG4105CQW	ribosome biogenesis GTPase YqeH
SN35N_0268	ENOG4105CND	Glycosyl transferase, family 2
SN35N_0270	ENOG4105KVH	Transcriptional regulator
SN35N_0271	ENOG4105CIS	alcohol dehydrogenase
SN35N_0272	ENOG4105D1H	recombination factor protein RarA
SN35N_0274	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SN35N_0275	ENOG4105VJV	50s ribosomal protein L35
SN35N_0276	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SN35N_0277	ENOG4105C22	threonyL-tRNA synthetase
SN35N_0280	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
SN35N_0281	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SN35N_0282	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
SN35N_0283	ENOG4105C2M	dna polymerase I
SN35N_0286	ENOG4105VG1	fes assembly suf system protein
SN35N_0287	ENOG4105DIW	FeS assembly protein SUFB
SN35N_0288	ENOG4108UNV	SUF system FeS assembly protein, NifU family
SN35N_0289	ENOG4105C9B	Cysteine desulfurase
SN35N_0290	ENOG4105JRK	feS assembly protein SufD
SN35N_0295	ENOG4105DFU	Cell wall formation (By similarity)
SN35N_0297	ENOG4108VDD	TRNA binding domain protein
SN35N_0299	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SN35N_0300	ENOG4108V15	phosphotransferase enzyme family
SN35N_0303	ENOG4105K59	histidine triad (HIT) protein
SN35N_0305	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
SN35N_0311	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_0313	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
SN35N_0318	ENOG4107QZ7	Cellulose synthase catalytic subunit
SN35N_0321	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SN35N_0322	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SN35N_0323	ENOG4108R6K	riboflavin synthase, subunit alpha
SN35N_0332	ENOG4107EFR	Flavocytochrome c
SN35N_0334	ENOG4105C5Q	Transcriptional regulator
SN35N_0337	ENOG4105EQI	Metal Dependent Phosphohydrolase
SN35N_0338	ENOG4106D4I	domain protein
SN35N_0339	ENOG4107VRP	DNA repair exonuclease
SN35N_0340	ENOG4105WZB	UPF0342 protein
SN35N_0341	ENOG4105BZ4	penicillin-binding protein
SN35N_0343	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
SN35N_0344	ENOG4105CHM	Aminotransferase
SN35N_0346	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_0348	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
SN35N_0350	ENOG4105CS2	ec 3.2.1.21
SN35N_0351	ENOG4105CK1	PTS System
SN35N_0352	ENOG4105VZJ	PTS System
SN35N_0353	ENOG4105VCP	PTS System
SN35N_0357	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SN35N_0359	ENOG4105C75	arginyL-tRNA synthetase
SN35N_0360	ENOG4107YB6	acetyltransferase, (GNAT) family
SN35N_0365	ENOG4105SFS	phosphoesterase RecJ domain protein
SN35N_0366	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
SN35N_0367	ENOG4107RIQ	Sulfate adenylate transferase
SN35N_0369	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SN35N_0392	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SN35N_0429	ENOG4105D85	methylase
SN35N_0431	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SN35N_0434	ENOG4105K56	Transcriptional regulator
SN35N_0438	ENOG4108WCX	response regulator
SN35N_0442	ENOG410667J	hydrolase
SN35N_0443	ENOG4108UZ3	Transporter
SN35N_0445	ENOG4105VUF	Transcriptional regulator
SN35N_0446	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SN35N_0447	ENOG4108NEV	two component transcriptional regulator, LytTR family
SN35N_0452	ENOG4105ECB	domain protein
SN35N_0452	ENOG4105ECB	domain protein
SN35N_0453	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SN35N_0454	ENOG4105ZMH	deoxynucleoside kinase
SN35N_0455	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
SN35N_0457	ENOG4105DRS	transport system, permease
SN35N_0458	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
SN35N_0459	ENOG4108IJ9	(ABC) transporter
SN35N_0461	ENOG4107QSE	Dipeptidase
SN35N_0462	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
SN35N_0465	ENOG4105C8T	Leucyl-tRNA synthetase
SN35N_0474	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_0475	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SN35N_0477	ENOG4105Q84	sucrose synthase
SN35N_0478	ENOG4107QK5	Homocysteine s-methyltransferase
SN35N_0479	ENOG4108IQI	permease
SN35N_0480	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SN35N_0481	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SN35N_0483	ENOG4108R1E	Serine threonine protein phosphatase 1
SN35N_0487	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SN35N_0489	ENOG4105E0M	Sulfatase
SN35N_0490	ENOG4107IN1	Protein of unknown function (DUF1797)
SN35N_0491	ENOG4105CHM	Aminotransferase
SN35N_0494	ENOG4105W2C	Glycosyl transferase
SN35N_0495	ENOG4105BZF	Glycosyl transferase (Group 1
SN35N_0496	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SN35N_0497	ENOG4105KRI	phosphocarrier protein (HPr
SN35N_0499	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SN35N_0502	ENOG4108JQ7	(ABC) transporter
SN35N_0504	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SN35N_0505	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
SN35N_0512	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
SN35N_0513	ENOG4105DC8	reductase
SN35N_0515	ENOG4105CMG	Carbohydrate kinase
SN35N_0516	ENOG4105C6Z	Gluconate
SN35N_0517	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
SN35N_0518	ENOG4105C02	permease
SN35N_0524	ENOG4105K4H	Nlp p60 protein
SN35N_0525	ENOG4105EVI	UPF0374 protein
SN35N_0526	ENOG410902V	Modulates RecA activity (By similarity)
SN35N_0533	ENOG4105D3Q	Sugar transferase
SN35N_0541	ENOG4105D5D	udp-galactopyranose mutase
SN35N_0546	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SN35N_0547	ENOG4105ER6	polysaccharide biosynthesis protein
SN35N_0549	ENOG4107QRS	glycosyltransferase group 2 family protein
SN35N_0552	ENOG4108KBE	Glycosyl transferase, family 2
SN35N_0553	ENOG4105D3Q	Sugar transferase
SN35N_0554	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
SN35N_0555	ENOG4107YJ4	chain length determinant protein
SN35N_0559	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
SN35N_0560	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SN35N_0561	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SN35N_0562	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SN35N_0567	ENOG4105EVB	acetyltransferase
SN35N_0568	ENOG4107VDP	teichoic acid biosynthesis
SN35N_0575	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_0577	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
SN35N_0579	ENOG4107R37	Glutamate dehydrogenase
SN35N_0580	ENOG4105DQ6	Transposase
SN35N_0585	ENOG4105CK1	PTS System
SN35N_0587	ENOG4105FDU	atp-dependent rna helicase
SN35N_0588	ENOG4105EE0	oxidoreductase
SN35N_0589	ENOG4105VEQ	Cold shock protein
SN35N_0592	ENOG4106KNT	transcriptional regulator
SN35N_0594	ENOG4105CK1	PTS System
SN35N_0597	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SN35N_0598	ENOG4105CBD	Diacylglycerol kinase
SN35N_0599	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SN35N_0600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SN35N_0601	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SN35N_0603	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SN35N_0604	ENOG4105C4R	Atp-dependent dna helicase
SN35N_0605	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
SN35N_0606	ENOG4108U5N	UPF0316 protein
SN35N_0607	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
SN35N_0608	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
SN35N_0613	ENOG4108JJ8	(ABC) transporter
SN35N_0614	ENOG4108JJ9	ABC, transporter
SN35N_0615	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SN35N_0616	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SN35N_0620	ENOG4105CUB	amino acid
SN35N_0622	ENOG4105C6K	Malic enzyme
SN35N_0624	ENOG4105CMU	LysR family (Transcriptional regulator
SN35N_0626	ENOG4107EFR	Flavocytochrome c
SN35N_0627	ENOG4105C9Q	fumarate hydratase class II
SN35N_0629	ENOG4105EKQ	RNA-directed DNA polymerase
SN35N_0635	ENOG4105F9F	transposase
SN35N_0638	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
SN35N_0642	ENOG4107QPK	)-transporter
SN35N_0643	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SN35N_0645	ENOG4105DSE	periplasmic solute binding protein
SN35N_0646	ENOG4105CC5	ABC transporter
SN35N_0647	ENOG4105DIK	(ABC) transporter
SN35N_0648	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
SN35N_0649	ENOG4105ID8	Transcriptional regulator, ARAC family
SN35N_0650	ENOG4106DSS	Tartrate dehydratase subunit alpha
SN35N_0651	ENOG4107GFK	fumarate
SN35N_0652	ENOG4105VG1	fes assembly suf system protein
SN35N_0653	ENOG4107QPK	)-transporter
SN35N_0654	ENOG4105D49	3-dehydroquinate synthase
SN35N_0655	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
SN35N_0656	ENOG4105E2X	shikimate dehydrogenase
SN35N_0657	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SN35N_0661	ENOG4108UJD	30S ribosomal protein S9
SN35N_0662	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SN35N_0663	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SN35N_0665	ENOG4108JJB	ABC transporter
SN35N_0666	ENOG4108JJB	ABC transporter
SN35N_0668	ENOG41088B0	Major membrane immunogen
SN35N_0673	ENOG4108ZT0	50S ribosomal protein l17
SN35N_0674	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SN35N_0675	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SN35N_0676	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SN35N_0677	ENOG41067V7	50S ribosomal protein L36
SN35N_0678	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SN35N_0679	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SN35N_0680	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SN35N_0681	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SN35N_0682	ENOG41084KY	50S ribosomal protein L30
SN35N_0683	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SN35N_0684	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SN35N_0685	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
SN35N_0686	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
SN35N_0687	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SN35N_0688	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SN35N_0689	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
SN35N_0690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SN35N_0691	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SN35N_0692	ENOG41082SA	50s ribosomal protein l29
SN35N_0693	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
SN35N_0694	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SN35N_0695	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SN35N_0696	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SN35N_0697	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SN35N_0698	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SN35N_0699	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SN35N_0700	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SN35N_0701	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SN35N_0703	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SN35N_0704	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SN35N_0705	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SN35N_0707	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SN35N_0708	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SN35N_0709	ENOG41062JF	Transcriptional regulator
SN35N_0710	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SN35N_0711	ENOG4105KEX	transcriptional regulator, ctsr
SN35N_0712	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SN35N_0713	ENOG4105ZMH	deoxynucleoside kinase
SN35N_0715	ENOG4108IQI	permease
SN35N_0717	ENOG41062ES	Transcriptional regulator
SN35N_0721	ENOG4108KGH	TRANSCRIPTIONal
SN35N_0723	ENOG4105DWK	Membrane
SN35N_0735	ENOG4105CAQ	asparagine synthetase
SN35N_0737	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SN35N_0747	ENOG41082BM	Transcriptional regulator, arsr family
SN35N_0748	ENOG4105EMS	pseudouridine synthase
SN35N_0749	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SN35N_0753	ENOG4105DZW	Dipeptidase
SN35N_0754	ENOG4105CU9	asparagine synthetase A
SN35N_0755	ENOG4105C5S	asparaginyl-tRNA synthetase
SN35N_0756	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
SN35N_0758	ENOG4107EFR	Flavocytochrome c
SN35N_0759	ENOG4107RSM	transcriptional regulator
SN35N_0762	ENOG4105DBI	uridine monophosphokinase
SN35N_0775	ENOG4105DZR	Type I site-specific deoxyribonuclease
SN35N_0776	ENOG4105CD8	aminopeptidase N
SN35N_0782	ENOG4105VBF	alkaline shock protein
SN35N_0785	ENOG4107BMA	Transglycosylase associated protein
SN35N_0786	ENOG4105EXC	Acyl-transferase
SN35N_0791	ENOG4108IMY	Transcriptional regulator
SN35N_0793	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SN35N_0794	ENOG4105CS9	pantothenic acid kinase
SN35N_0795	ENOG4105EA8	2-Nitropropane dioxygenase
SN35N_0796	ENOG4105EEM	helicase
SN35N_0797	ENOG4105DQR	SNARE associated Golgi
SN35N_0798	ENOG4105RHY	Pfam:UPF0157
SN35N_0800	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SN35N_0802	ENOG4105D5G	Transposase
SN35N_0804	ENOG4105KPY	Small multidrug resistance protein
SN35N_0806	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
SN35N_0812	ENOG4105K56	Transcriptional regulator
SN35N_0814	ENOG4107R7I	amino acid
SN35N_0815	ENOG410901P	UPF0249 protein
SN35N_0816	ENOG4105C5Y	PTS System
SN35N_0818	ENOG4105CI1	PTS System
SN35N_0822	ENOG4105DRP	amino acid AbC transporter
SN35N_0823	ENOG4105EAD	ABC transporter
SN35N_0824	ENOG4105CT1	(ABC) transporter
SN35N_0828	ENOG4105C5I	Dehydrogenase
SN35N_0829	ENOG4105CHM	Aminotransferase
SN35N_0830	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SN35N_0835	ENOG4105DQ6	Transposase
SN35N_0836	ENOG4105G5W	regulator Fur family
SN35N_0837	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SN35N_0839	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
SN35N_0842	ENOG4105CUB	amino acid
SN35N_0845	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
SN35N_0846	ENOG4105EXC	Acyl-transferase
SN35N_0849	ENOG4105C7K	acetolactate synthase
SN35N_0850	ENOG4105DTN	riboflavin biosynthesis protein ribF
SN35N_0851	ENOG4105C7K	acetolactate synthase
SN35N_0852	ENOG4105C7N	Xanthine uracil vitamin C permease
SN35N_0855	ENOG4105KPE	licD family
SN35N_0857	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
SN35N_0858	ENOG4105D49	3-dehydroquinate synthase
SN35N_0859	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_0862	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
SN35N_0864	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
SN35N_0868	ENOG4108DBC	nitroreductase
SN35N_0871	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
SN35N_0873	ENOG4108HCJ	Hydrolase
SN35N_0875	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SN35N_0876	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
SN35N_0881	ENOG4107SUZ	Sodium/hydrogen exchanger family
SN35N_0882	ENOG4105D4A	Cell wall formation (By similarity)
SN35N_0883	ENOG4105EP9	oxidoreductase
SN35N_0884	ENOG4105CGK	Exodeoxyribonuclease III
SN35N_0885	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SN35N_0887	ENOG4105K8N	protein family UPF0079, ATPase
SN35N_0888	ENOG4108IJ2	phosphate acetyltransferase
SN35N_0889	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SN35N_0892	ENOG4105CDA	abc transporter atp-binding protein
SN35N_0893	ENOG4105E5Q	amino acid AbC transporter
SN35N_0896	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
SN35N_0897	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SN35N_0899	ENOG4105XZU	Preprotein translocase, subunit SecG
SN35N_0900	ENOG4105CMQ	Chloride channel
SN35N_0903	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SN35N_0904	ENOG4105CP7	Triose-phosphate isomerase
SN35N_0905	ENOG4105BZA	Phosphoglycerate kinase
SN35N_0906	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
SN35N_0908	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SN35N_0909	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SN35N_0910	ENOG4105C5I	Dehydrogenase
SN35N_0911	ENOG4107QSI	ABC, transporter
SN35N_0912	ENOG4105CIE	May be required for sporulation (By similarity)
SN35N_0914	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
SN35N_0916	ENOG4105CH7	arginosuccinase
SN35N_0917	ENOG4105CDH	Citrulline--aspartate ligase
SN35N_0918	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
SN35N_0919	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SN35N_0920	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SN35N_0924	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_0928	ENOG4105H67	Protein of unknown function (DUF421)
SN35N_0929	ENOG4105C3M	thioredoxin reductase
SN35N_0930	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_0933	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SN35N_0934	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SN35N_0935	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
SN35N_0936	ENOG41086DT	Membrane protein of unknown function
SN35N_0937	ENOG41067S9	phage shock protein C, PspC
SN35N_0938	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
SN35N_0939	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SN35N_0940	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SN35N_0941	ENOG4105E2Z	phosphate ABC transporter (Permease
SN35N_0942	ENOG4105C8U	phosphate abc transporter
SN35N_0943	ENOG4105CVA	phosphate
SN35N_0944	ENOG4105BZU	Histidine kinase
SN35N_0945	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SN35N_0947	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SN35N_0948	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SN35N_0952	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SN35N_0953	ENOG4105CVA	phosphate
SN35N_0954	ENOG4105ESV	Glycosyl transferase, family 4
SN35N_0955	ENOG4105C0X	amino acid
SN35N_0956	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SN35N_0957	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SN35N_0959	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
SN35N_0960	ENOG4105C5H	ABC transporter
SN35N_0961	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SN35N_0962	ENOG410801F	ribosomal-protein-alanine acetyltransferase
SN35N_0963	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
SN35N_0964	ENOG41072GX	Peptidase M22 Glycoprotease
SN35N_0966	ENOG4105D5T	phosphonate abc transporter
SN35N_0968	ENOG4105S7S	phosphonate abc transporter
SN35N_0969	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
SN35N_0970	ENOG4107STF	Involved in phosphonate degradation (By similarity)
SN35N_0971	ENOG4105CMR	udp-glucose 4-epimerase
SN35N_0973	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
SN35N_0974	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
SN35N_0975	ENOG4105FA2	dna polymerase iii
SN35N_0976	ENOG4105X0R	protein from nitrogen regulatory protein P-II
SN35N_0977	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SN35N_0979	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SN35N_0980	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SN35N_0981	ENOG4105C6E	dna polymerase iii
SN35N_0983	ENOG4107Y49	methyltransferase
SN35N_0984	ENOG41067VN	Glutaredoxin
SN35N_0985	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SN35N_0987	ENOG4108URH	decarboxylase
SN35N_1016	ENOG4105IG6	Phage terminase, large subunit
SN35N_1056	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SN35N_1057	ENOG4108VZM	50s ribosomal protein L10
SN35N_1058	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
SN35N_1059	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SN35N_1061	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SN35N_1063	ENOG4107FTN	50S ribosomal protein L33
SN35N_1066	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SN35N_1067	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SN35N_1068	ENOG4105C8N	cysteinyl-tRNA synthetase
SN35N_1069	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SN35N_1071	ENOG4105CTP	PilT protein domain protein
SN35N_1073	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
SN35N_1075	ENOG4105E66	phosphoriboisomerase A
SN35N_1076	ENOG4105CTZ	aminopeptidase c
SN35N_1079	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SN35N_1080	ENOG4108TVT	permease
SN35N_1082	ENOG4108KGH	TRANSCRIPTIONal
SN35N_1083	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SN35N_1085	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SN35N_1087	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SN35N_1088	ENOG4108EQA	pts system
SN35N_1089	ENOG4108EQA	pts system
SN35N_1090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SN35N_1092	ENOG4105F3R	pts system mannose fructose sorbose family iid
SN35N_1093	ENOG4105ETZ	PTS System
SN35N_1096	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
SN35N_1097	ENOG4105D6E	homoserine dehydrogenase
SN35N_1098	ENOG410906U	SprT-like
SN35N_1102	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
SN35N_1103	ENOG4105DAP	Nicotinate phosphoribosyltransferase
SN35N_1105	ENOG4105FDP	GntR family transcriptional regulator
SN35N_1107	ENOG4105II7	pyrroline-5-carboxylate reductase
SN35N_1108	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
SN35N_1116	ENOG4105F9F	transposase
SN35N_1118	ENOG4107QTZ	amino acid
SN35N_1131	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
SN35N_1133	ENOG4105DUX	Transporter
SN35N_1134	ENOG4105CRK	lysyL-tRNA synthetase
SN35N_1135	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SN35N_1136	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
SN35N_1139	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SN35N_1140	ENOG41060GV	RNA binding s1 domain protein
SN35N_1142	ENOG41082I2	s4 domain protein
SN35N_1144	ENOG4108JA2	transcriptioN-repair coupling factor
SN35N_1145	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SN35N_1146	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SN35N_1150	ENOG4105DBV	ornithine carbamoyltransferase
SN35N_1151	ENOG4105C8Y	Acetylornithine aminotransferase
SN35N_1152	ENOG4105CAS	nag kinase
SN35N_1153	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SN35N_1154	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SN35N_1155	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SN35N_1160	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SN35N_1161	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
SN35N_1162	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SN35N_1163	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SN35N_1164	ENOG4105C1J	atp-dependent rna helicase
SN35N_1165	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
SN35N_1167	ENOG4105D0M	Protease HtpX homolog
SN35N_1168	ENOG4108V0P	LemA family
SN35N_1169	ENOG4108Z6X	(sortase) family
SN35N_1171	ENOG41082DI	50s ribosomal protein l31
SN35N_1172	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SN35N_1173	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SN35N_1176	ENOG4105EJQ	L-serine dehydratase
SN35N_1178	ENOG4105C44	Serine transporter
SN35N_1179	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SN35N_1180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SN35N_1181	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
SN35N_1183	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
SN35N_1184	ENOG4105DCI	Phosphohydrolase
SN35N_1188	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SN35N_1190	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SN35N_1191	ENOG4105DFT	pur operon repressor
SN35N_1192	ENOG4105CC5	ABC transporter
SN35N_1193	ENOG4105FDK	ABC transporter
SN35N_1195	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SN35N_1196	ENOG4105W42	Veg protein
SN35N_1197	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SN35N_1198	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
SN35N_1199	ENOG4105F8V	Hydrolase, tatD family
SN35N_1200	ENOG4105C2C	drug resistance transporter, Bcr CflA
SN35N_1201	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SN35N_1204	ENOG4105I3N	Conserved Protein
SN35N_1205	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SN35N_1211	ENOG4105DKQ	ROK family
SN35N_1212	ENOG4105CS2	ec 3.2.1.21
SN35N_1213	ENOG4105CK1	PTS System
SN35N_1216	ENOG4105CK1	PTS System
SN35N_1217	ENOG4108S3Y	transcriptional regulator
SN35N_1218	ENOG4105C31	Tryptophanyl-tRNA synthetase
SN35N_1219	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SN35N_1220	ENOG4105EEM	helicase
SN35N_1228	ENOG4108JJA	ABC, transporter
SN35N_1232	ENOG4108WCX	response regulator
SN35N_1240	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
SN35N_1241	ENOG410667J	hydrolase
SN35N_1242	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
SN35N_1243	ENOG4108HCJ	Hydrolase
SN35N_1245	ENOG4108UW5	maltose o-acetyltransferase
SN35N_1264	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_1265	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
SN35N_1266	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
SN35N_1268	ENOG4108IJ8	ABC transporter
SN35N_1271	ENOG4105E1F	short-chain dehydrogenase reductase
SN35N_1272	ENOG4105DU0	nucleoside hydrolase
SN35N_1277	ENOG4105KIS	phospholipid-binding protein
SN35N_1278	ENOG4105KA3	membrAne
SN35N_1280	ENOG4105E66	phosphoriboisomerase A
SN35N_1284	ENOG4105BZU	Histidine kinase
SN35N_1285	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_1288	ENOG4105EY8	ABC transporter
SN35N_1294	ENOG41080Y5	BioY family
SN35N_1296	ENOG4105DZW	Dipeptidase
SN35N_1298	ENOG4105DQ6	Transposase
SN35N_1304	ENOG4108EKI	Dehydrogenase
SN35N_1306	ENOG4105CZV	ABC transporter
SN35N_1307	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_1313	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SN35N_1316	ENOG4108HM4	ABC transporter
SN35N_1318	ENOG4105CEP	NADH dehydrogenase
SN35N_1319	ENOG4108U05	Transcriptional regulator
SN35N_1321	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SN35N_1327	ENOG41068JE	domain protein
SN35N_1329	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
SN35N_1333	ENOG4107WD8	ABC transporter, permease
SN35N_1335	ENOG4108R3E	Dna-3-methyladenine glycosylase i
SN35N_1336	ENOG4105EYF	MMPL domain protein
SN35N_1340	ENOG4105CQB	FAD linked oxidase domain protein
SN35N_1341	ENOG4108KGH	TRANSCRIPTIONal
SN35N_1344	ENOG4105CK1	PTS System
SN35N_1347	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SN35N_1348	ENOG4105GR3	Histidine kinase
SN35N_1350	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_1354	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SN35N_1355	ENOG4105MKU	Transcriptional regulator
SN35N_1356	ENOG4108Z40	Transcriptional regulator
SN35N_1357	ENOG41062SP	
SN35N_1358	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SN35N_1361	ENOG4107SJB	teichoic acid biosynthesis
SN35N_1362	ENOG4107SJB	teichoic acid biosynthesis
SN35N_1363	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
SN35N_1365	ENOG4105C5Y	PTS System
SN35N_1366	ENOG4105C5Y	PTS System
SN35N_1367	ENOG4105CG3	alpha amylase, catalytic region
SN35N_1368	ENOG4107414	GntR family transcriptional regulator
SN35N_1372	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SN35N_1374	ENOG4105C6T	cysteine synthase
SN35N_1375	ENOG4105C28	cystathionine
SN35N_1376	ENOG4105D7W	serine acetyltransferase
SN35N_1380	ENOG41069H0	dihydroorotase EC 3.5.2.3
SN35N_1383	ENOG4105CK1	PTS System
SN35N_1384	ENOG4105FDP	GntR family transcriptional regulator
SN35N_1385	ENOG4108YYH	Nadph-dependent fmn reductase
SN35N_1390	ENOG4105K63	Thioredoxin
SN35N_1392	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
SN35N_1393	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
SN35N_1395	ENOG4105CTS	PTS system mannitol-specific
SN35N_1396	ENOG4105DZW	Dipeptidase
SN35N_1400	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
SN35N_1403	ENOG4105KP9	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SN35N_1405	ENOG4108V06	Glutathione peroxidase
SN35N_1407	ENOG4108JJB	ABC transporter
SN35N_1411	ENOG4106A8V	Protein CrcB homolog
SN35N_1413	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SN35N_1414	ENOG4105F23	Fibronectin-binding protein
SN35N_1417	ENOG4105CPC	Aldo Keto reductase
SN35N_1418	ENOG4105CVJ	phosphoglycerate mutase
SN35N_1419	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
SN35N_1420	ENOG4108JQ1	Dehydrogenase
SN35N_1427	ENOG4105DQ6	Transposase
SN35N_1430	ENOG4105C5Q	Transcriptional regulator
SN35N_1432	ENOG4105DFD	Na H antiporter
SN35N_1435	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_1436	ENOG4108HKT	sucrose-6-phosphate hydrolase
SN35N_1437	ENOG4105C5Y	PTS System
SN35N_1438	ENOG4105DME	alpha-galactosidase
SN35N_1439	ENOG4105EVU	fructokinase
SN35N_1443	ENOG4108IJ9	(ABC) transporter
SN35N_1444	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
SN35N_1446	ENOG4105EG2	ABC transporter, permease
SN35N_1447	ENOG4105D56	permease protein
SN35N_1448	ENOG4107FKK	extracellular solute-binding protein family 1
SN35N_1449	ENOG4105CG3	alpha amylase, catalytic region
SN35N_1450	ENOG4105FKQ	transcriptional regulator
SN35N_1452	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_1453	ENOG4105VDH	Dihydroxyacetone kinase
SN35N_1454	ENOG4108UTZ	Dihydroxyacetone kinase
SN35N_1455	ENOG4105CMT	Dihydroxyacetone kinase
SN35N_1456	ENOG4105CMT	Dihydroxyacetone kinase
SN35N_1458	ENOG4105X71	Membrane
SN35N_1459	ENOG4105C10	Electron transfer flavoprotein
SN35N_1462	ENOG4105CIG	ABC transporter
SN35N_1463	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
SN35N_1468	ENOG4108TZY	GntR Family Transcriptional Regulator
SN35N_1470	ENOG4108V7D	UPF0397 protein
SN35N_1471	ENOG4108JJB	ABC transporter
SN35N_1472	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
SN35N_1478	ENOG4107S5I	aldo keto reductase
SN35N_1480	ENOG4105DJ2	Major Facilitator Superfamily
SN35N_1487	ENOG41067S9	phage shock protein C, PspC
SN35N_1491	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
SN35N_1499	ENOG4108Z86	Glutamine amidotransferase
SN35N_1501	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SN35N_1502	ENOG4105DWF	phosphomethylpyrimidine kinase
SN35N_1503	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
SN35N_1504	ENOG4105CIS	alcohol dehydrogenase
SN35N_1505	ENOG4105DVM	PP-loop domain protein
SN35N_1506	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_1509	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
SN35N_1510	ENOG4105QUH	Domain of unknown function (DUF2088)
SN35N_1511	ENOG4105TV1	Transcriptional regulator
SN35N_1512	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
SN35N_1513	ENOG41082M7	Cobalt transport protein
SN35N_1514	ENOG4108JJB	ABC transporter
SN35N_1520	ENOG4105D1Q	UPF0246 protein
SN35N_1521	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
SN35N_1525	ENOG4105CIS	alcohol dehydrogenase
SN35N_1532	ENOG4107YCK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
SN35N_1536	ENOG4105EFA	4-hydroxyphenylacetate
SN35N_1537	ENOG4105M2Z	protein tyrosine serine phosphatase
SN35N_1539	ENOG4107QHE	Choloylglycine hydrolase
SN35N_1540	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
SN35N_1541	ENOG4105G9B	Transcriptional regulator
SN35N_1542	ENOG4108TVJ	Nitroreductase
SN35N_1544	ENOG4105DTD	Dehydrogenase
SN35N_1545	ENOG4108UXE	Protein tyrosine phosphatase
SN35N_1548	ENOG4107QPK	)-transporter
SN35N_1549	ENOG4107EFR	Flavocytochrome c
SN35N_1553	ENOG4108RG0	uracil-dna glycosylase
SN35N_1554	ENOG4107RGH	Aldehyde dehydrogenase
SN35N_1557	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SN35N_1558	ENOG4105C0H	protease
SN35N_1559	ENOG4105Q2H	domain protein
SN35N_1562	ENOG4105BZU	Histidine kinase
SN35N_1563	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SN35N_1565	ENOG4105VEQ	Cold shock protein
SN35N_1567	ENOG4105C71	hydrolase family 65, central catalytic
SN35N_1568	ENOG4107URF	beta-phospho-glucomutase
SN35N_1570	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SN35N_1572	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
SN35N_1574	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
SN35N_1575	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SN35N_1576	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SN35N_1577	ENOG4108J59	Extracellular solute-binding protein, family 5
SN35N_1578	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SN35N_1579	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SN35N_1580	ENOG410605W	Major Facilitator
SN35N_1581	ENOG4105CDU	Replicative dna helicase
SN35N_1582	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
SN35N_1584	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SN35N_1585	ENOG4108UUM	single-stranded DNA-binding protein
SN35N_1586	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
SN35N_1588	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SN35N_1589	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SN35N_1590	ENOG410848D	S4 domain protein YaaA
SN35N_1591	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SN35N_1592	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SN35N_1594	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
SN35N_1595	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SN35N_1597	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SN35N_1598	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SN35N_1603	ENOG4105F9F	transposase
SN35N_1604	ENOG4105C3F	Signal peptidase i
SN35N_1611	ENOG4105PY6	Phenolic acid decarboxylase
SN35N_1612	ENOG4105U3E	Transcriptional regulator
SN35N_1614	ENOG4108EKI	Dehydrogenase
SN35N_1615	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_1617	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
SN35N_1618	ENOG4105EV1	Ribose uptake protein RbsU
SN35N_1619	ENOG4105CHR	reductase
SN35N_1622	ENOG410787A	Pts system, glucitol sorbitol-specific
SN35N_1623	ENOG4105DZY	Pts system, glucitol sorbitol-specific
SN35N_1625	ENOG4105C7K	acetolactate synthase
SN35N_1626	ENOG4108Z40	Transcriptional regulator
SN35N_1627	ENOG4105C7K	acetolactate synthase
SN35N_1633	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
SN35N_1636	ENOG4108WCX	response regulator
SN35N_1637	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
SN35N_1638	ENOG4105CH6	catalase
SN35N_1639	ENOG4107BMA	Transglycosylase associated protein
SN35N_1645	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
SN35N_1646	ENOG4105CMD	Transcriptional regulator, GntR family
SN35N_1647	ENOG4107QNK	)-transporter
SN35N_1650	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
SN35N_1651	ENOG4108UW5	maltose o-acetyltransferase
SN35N_1653	ENOG4107QRI	Phosphoketolase
SN35N_1654	ENOG4105E98	transcriptional regulator DeoR family
SN35N_1657	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
SN35N_1658	ENOG4105DT3	PTS system, galactitol-specific IIc component
SN35N_1661	ENOG4105ETD	TRANSCRIPTIONal
SN35N_1665	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SN35N_1668	ENOG4107QHE	Choloylglycine hydrolase
SN35N_1672	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_1675	ENOG4105C5Y	PTS System
SN35N_1676	ENOG4105CS2	ec 3.2.1.21
SN35N_1677	ENOG4105CS2	ec 3.2.1.21
SN35N_1678	ENOG4105CID	antiterminator
SN35N_1680	ENOG4105CS2	ec 3.2.1.21
SN35N_1682	ENOG4105RD7	BadF BadG BcrA BcrD
SN35N_1683	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SN35N_1684	ENOG4105CK1	PTS System
SN35N_1685	ENOG4108X79	transcriptional regulator
SN35N_1686	ENOG41088PD	hydrolase
SN35N_1688	ENOG4105EMV	Major Facilitator
SN35N_1689	ENOG4105DUM	transcriptional regulator, lysR family
SN35N_1694	ENOG4105EMV	Major Facilitator
SN35N_1695	ENOG4105C5Q	Transcriptional regulator
SN35N_1696	ENOG4105E2X	shikimate dehydrogenase
SN35N_1697	ENOG4105FF2	Type I DHQase
SN35N_1702	ENOG4105CPC	Aldo Keto reductase
SN35N_1703	ENOG4105CQ4	Transcriptional regulator
SN35N_1704	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
SN35N_1705	ENOG4107RBJ	symporter
SN35N_1706	ENOG4105DME	alpha-galactosidase
SN35N_1709	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
SN35N_1710	ENOG4105CMR	udp-glucose 4-epimerase
SN35N_1711	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
SN35N_1712	ENOG4105CQ4	Transcriptional regulator
SN35N_1713	ENOG4105W08	virulence gene repressor rsal
SN35N_1714	ENOG4105MZU	cell filamentation protein
SN35N_1718	ENOG4107UWP	Major facilitator superfamily MFS_1
SN35N_1725	ENOG4107RBJ	symporter
SN35N_1726	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
SN35N_1728	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_1738	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_1742	ENOG4105C9K	Endothelin-converting enzyme 1
SN35N_1743	ENOG4105IJJ	transcriptional regulator, crp fnr family
SN35N_1749	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SN35N_1750	ENOG4105C59	p-type ATPase
SN35N_1753	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SN35N_1755	ENOG4105EJ2	Transcriptional regulator
SN35N_1763	ENOG4105CVK	Glutamate decarboxylase
SN35N_1768	ENOG41075H3	AraC family transcriptional regulator
SN35N_1777	ENOG4108UVJ	appr-1-p processing domain protein
SN35N_1778	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SN35N_1784	ENOG4105CGH	5'-nucleotidase
SN35N_1794	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_1797	ENOG4105NA0	Transcriptional regulator
SN35N_1799	ENOG4107QHE	Choloylglycine hydrolase
SN35N_1802	ENOG4108UZ3	Transporter
SN35N_1807	ENOG4105VN1	Heat shock protein
SN35N_1810	ENOG4105CEN	a g-specific adenine glycosylase
SN35N_1812	ENOG4105K78	MarR family Transcriptional regulator
SN35N_1816	ENOG4108W5N	phosphatidylglycerophosphatase a
SN35N_1818	ENOG4105C85	amino acid
SN35N_1820	ENOG4105DFD	Na H antiporter
SN35N_1822	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SN35N_1823	ENOG4105CPN	adenine deaminase
SN35N_1825	ENOG4105UNS	Pfam:DUF419
SN35N_1827	ENOG4105C59	p-type ATPase
SN35N_1828	ENOG4105C94	Transporter
SN35N_1833	ENOG4107RGM	aldo keto reductase
SN35N_1834	ENOG4105VG1	fes assembly suf system protein
SN35N_1835	ENOG4105F1A	Pyruvate formate-lyase
SN35N_1836	ENOG4105C6N	Formate acetyltransferase
SN35N_1837	ENOG4107S1E	Beta-lactamase
SN35N_1840	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_1841	ENOG4105DSE	periplasmic solute binding protein
SN35N_1845	ENOG4105EUJ	GTP cyclohydrolase i
SN35N_1847	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SN35N_1853	ENOG4105PGM	cation diffusion facilitator family transporter
SN35N_1855	ENOG4108UT2	hemolysin iii
SN35N_1859	ENOG4106F5Q	Membrane
SN35N_1861	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SN35N_1862	ENOG4105CUB	amino acid
SN35N_1864	ENOG4105ECB	domain protein
SN35N_1867	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
SN35N_1868	ENOG4105M2Z	protein tyrosine serine phosphatase
SN35N_1869	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
SN35N_1870	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SN35N_1871	ENOG4105C83	adenylosuccinate lyase
SN35N_1873	ENOG4105DC8	reductase
SN35N_1874	ENOG4105BZW	Glycerate kinase
SN35N_1876	ENOG4105FE1	phytoene synthase
SN35N_1877	ENOG4105EWK	phytoene
SN35N_1880	ENOG4108RCR	degv family
SN35N_1882	ENOG41083D3	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity)
SN35N_1887	ENOG4105G5W	regulator Fur family
SN35N_1894	ENOG4105C5Y	PTS System
SN35N_1898	ENOG4105EMD	TRANSCRIPTIONal
SN35N_1899	ENOG4105DM4	PTS System
SN35N_1900	ENOG4108YRF	PTS System
SN35N_1901	ENOG4105DM4	PTS System
SN35N_1902	ENOG4105C8I	hydrolase, family 38
SN35N_1904	ENOG410667J	hydrolase
SN35N_1907	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SN35N_1908	ENOG41083J0	(ABC) transporter
SN35N_1909	ENOG4105C4B	ABC transporter, permease
SN35N_1913	ENOG4105CG3	alpha amylase, catalytic region
SN35N_1914	ENOG4105C5Y	PTS System
SN35N_1919	ENOG4105EAB	amino acid AbC transporter
SN35N_1920	ENOG4105CDA	abc transporter atp-binding protein
SN35N_1921	ENOG4105DRP	amino acid AbC transporter
SN35N_1922	ENOG4105EAB	amino acid AbC transporter
SN35N_1923	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_1924	ENOG4105W8I	Transcriptional regulator
SN35N_1928	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SN35N_1930	ENOG4107QJE	Chromosome Partitioning Protein
SN35N_1931	ENOG4105FA0	parb-like partition protein
SN35N_1932	ENOG4105VDK	protein, conserved in bacteria
SN35N_1933	ENOG4105C3G	gtp-binding protein
SN35N_1935	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SN35N_1942	ENOG4107TCE	N-acetyltransferase
SN35N_1950	ENOG4105D9P	serine threonine protein kinase
SN35N_1952	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
SN35N_1955	ENOG4106F5Q	Membrane
SN35N_1956	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SN35N_1957	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SN35N_1959	ENOG4108W8B	Beta-lactamase domain protein
SN35N_1961	ENOG4105ECB	domain protein
SN35N_1963	ENOG4108V4B	ThiJ pfpI
SN35N_1966	ENOG4105DQ6	Transposase
SN35N_1987	ENOG4108FPN	Integrase
SN35N_1990	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SN35N_1996	ENOG4105KVH	Transcriptional regulator
SN35N_2000	ENOG4105C26	Dehydrogenase
SN35N_2002	ENOG4107Z3H	Transcriptional regulator, TetR family
SN35N_2004	ENOG4108WCX	response regulator
SN35N_2007	ENOG4105CAQ	asparagine synthetase
SN35N_2010	ENOG4105CAQ	asparagine synthetase
SN35N_2014	ENOG4105F27	Major Facilitator
SN35N_2015	ENOG4105KVH	Transcriptional regulator
SN35N_2016	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
SN35N_2024	ENOG4105CPQ	Dehydrogenase
SN35N_2036	ENOG4105C59	p-type ATPase
SN35N_2041	ENOG4107SC7	Inner membrane transporter yjeM
SN35N_2045	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
SN35N_2048	ENOG4105BZ1	(ABC) transporter
SN35N_2049	ENOG4105BZ1	(ABC) transporter
SN35N_2053	ENOG4105CHR	reductase
SN35N_2059	ENOG4107GJV	short-chain dehydrogenase reductase
SN35N_2063	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SN35N_2065	ENOG4105BZU	Histidine kinase
SN35N_2068	ENOG4105DSE	periplasmic solute binding protein
SN35N_2073	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
SN35N_2074	ENOG4105VUF	Transcriptional regulator
SN35N_2076	ENOG4105CS2	ec 3.2.1.21
SN35N_2077	ENOG4105CK1	PTS System
SN35N_2078	ENOG4105VZJ	PTS System
SN35N_2087	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SN35N_2089	ENOG4107YCR	Transcriptional regulator, ARSR family
SN35N_2093	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SN35N_2095	ENOG4105WH5	Teichoic acid glycosylation protein
SN35N_2098	ENOG4105CP9	extracellular ligand-binding receptor
SN35N_2099	ENOG4105C32	Amino acid ABC transporter (Permease)
SN35N_2100	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SN35N_2101	ENOG4105C0Z	ABC transporter
SN35N_2102	ENOG4108IV0	ABC, transporter
SN35N_2109	ENOG4105C7J	ABC transporter, permease
SN35N_2110	ENOG4105E2Y	ABC, transporter
SN35N_2111	ENOG4105CI1	PTS System
SN35N_2112	ENOG4108TVJ	Nitroreductase
SN35N_2114	ENOG4105BZ1	(ABC) transporter
SN35N_2115	ENOG41066F8	ROK family
SN35N_2120	ENOG4108UZ3	Transporter
SN35N_2129	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
SN35N_2130	ENOG4105C8P	)-transporter
SN35N_2131	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
SN35N_2137	ENOG4107YDN	peptide deformylase
SN35N_2139	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
SN35N_2140	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
SN35N_2141	ENOG4107XTP	(EAL) domain protein
SN35N_2142	ENOG4105BZU	Histidine kinase
SN35N_2149	ENOG4105DEU	major facilitator superfamily
SN35N_2150	ENOG4105CUB	amino acid
SN35N_2151	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
SN35N_2154	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SN35N_2155	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SN35N_2157	ENOG4108HCJ	Hydrolase
SN35N_2158	ENOG4105C5H	ABC transporter
SN35N_2163	ENOG4105ZT7	DNA-entry nuclease
SN35N_2165	ENOG4107YCR	Transcriptional regulator, ARSR family
SN35N_2167	ENOG4105ECB	domain protein
SN35N_2167	ENOG4105ECB	domain protein
SN35N_2169	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_2170	ENOG4105BZ1	(ABC) transporter
SN35N_2171	ENOG4105BZ1	(ABC) transporter
SN35N_2173	ENOG4105CPC	Aldo Keto reductase
SN35N_2175	ENOG4105C87	Aminotransferase class I and II
SN35N_2179	ENOG4108UW5	maltose o-acetyltransferase
SN35N_2180	ENOG4107YZX	Universal stress protein
SN35N_2182	ENOG4105WT3	Transcriptional regulator
SN35N_2189	ENOG4105CV8	reductase
SN35N_2190	ENOG4105CV8	reductase
SN35N_2191	ENOG4105EMU	Dehydrogenase
SN35N_2192	ENOG4105VUF	Transcriptional regulator
SN35N_2198	ENOG4105CSC	Glucose uptake protein
SN35N_2199	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SN35N_2203	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SN35N_2204	ENOG4105CPQ	Dehydrogenase
SN35N_2206	ENOG4105DQ6	Transposase
SN35N_2208	ENOG4108KB2	LysR family Transcriptional regulator
SN35N_2213	ENOG4108W0I	acetyltransferase
SN35N_2215	ENOG4105C3F	Signal peptidase i
SN35N_2216	ENOG4105C3F	Signal peptidase i
SN35N_2218	ENOG4105CSM	endonuclease III
SN35N_2223	ENOG4105VUF	Transcriptional regulator
SN35N_2226	ENOG4107GJV	short-chain dehydrogenase reductase
SN35N_2228	ENOG4108IUX	(ABC) transporter
SN35N_2230	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SN35N_2233	ENOG4105E2K	Glycosyl transferase (Group 1
SN35N_2234	ENOG4107XU6	Glycosyl transferase (Group 1
SN35N_2235	ENOG4105DUM	transcriptional regulator, lysR family
SN35N_2236	ENOG4105HMI	Membrane
SN35N_2241	ENOG4105EQ0	Major Facilitator superfamily
SN35N_2242	ENOG4108IJ0	Aspartate ammonia-lyase
SN35N_2250	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SN35N_2251	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
SN35N_2254	ENOG4108Z5V	transcriptional regulator, merr family
SN35N_2255	ENOG4108Z5V	transcriptional regulator, merr family
SN35N_2256	ENOG4108UQV	Membrane
SN35N_2262	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SN35N_2263	ENOG4105PUK	Membrane
SN35N_2268	ENOG4105D5G	Transposase
SN35N_2272	ENOG4105E5D	amino acid
SN35N_2273	ENOG4105FF2	Type I DHQase
SN35N_2279	ENOG4105NQC	Flavodoxin
SN35N_2283	ENOG4108UZ3	Transporter
SN35N_2284	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
SN35N_2288	ENOG4105K64	Glycosyl transferase, family 2
SN35N_2289	ENOG4107414	GntR family transcriptional regulator
SN35N_2290	ENOG4105VZJ	PTS System
SN35N_2291	ENOG4105VCP	PTS System
SN35N_2292	ENOG4105CS2	ec 3.2.1.21
SN35N_2293	ENOG4105CS2	ec 3.2.1.21
SN35N_2294	ENOG4105BZC	d-serine deaminase
SN35N_2297	ENOG4105MKU	Transcriptional regulator
SN35N_2298	ENOG4105DAP	Nicotinate phosphoribosyltransferase
SN35N_2306	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SN35N_2307	ENOG4108UW5	maltose o-acetyltransferase
SN35N_2309	ENOG410667J	hydrolase
SN35N_2310	ENOG4105D98	threonine synthase
SN35N_2311	ENOG4108IUK	alpha amylase, catalytic
SN35N_2315	ENOG4105C87	Aminotransferase class I and II
SN35N_2319	ENOG4105WH5	Teichoic acid glycosylation protein
SN35N_2321	ENOG4107YZX	Universal stress protein
SN35N_2323	ENOG4105DVE	abc transporter atp-binding protein
SN35N_2324	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_2327	ENOG4105C19	ABC transporter
SN35N_2328	ENOG4105HDK	L-asparaginase
SN35N_2331	ENOG4105M2Z	protein tyrosine serine phosphatase
SN35N_2332	ENOG4105DF9	Lipoate-protein, ligase
SN35N_2333	ENOG4107EFR	Flavocytochrome c
SN35N_2334	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SN35N_2335	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SN35N_2336	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
SN35N_2337	ENOG4105C8V	SAICAR synthetase
SN35N_2338	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
SN35N_2339	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
SN35N_2340	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
SN35N_2341	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
SN35N_2342	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SN35N_2343	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SN35N_2344	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SN35N_2345	ENOG4105C12	Phosphoribosylglycinamide synthetase
SN35N_2347	ENOG4105CND	Glycosyl transferase, family 2
SN35N_2352	ENOG4105C7N	Xanthine uracil vitamin C permease
SN35N_2354	ENOG4105G9B	Transcriptional regulator
SN35N_2355	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
SN35N_2356	ENOG4105CXT	aspartate transcarbamylase
SN35N_2357	ENOG4105CD3	dihydroorotase
SN35N_2358	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SN35N_2359	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SN35N_2360	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
SN35N_2361	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SN35N_2362	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SN35N_2364	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SN35N_2365	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
SN35N_2368	ENOG4107ZGM	malolactic fermentation system
SN35N_2371	ENOG4105CHM	Aminotransferase
SN35N_2372	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_2373	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
SN35N_2375	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
SN35N_2376	ENOG4107TXC	Transcriptional regulator
SN35N_2377	ENOG410605W	Major Facilitator
SN35N_2378	ENOG4107SUZ	Sodium/hydrogen exchanger family
SN35N_2379	ENOG4105MTF	NrdI protein
SN35N_2381	ENOG4105C37	(CBS) domain
SN35N_2389	ENOG4108Z66	YbaK ebsC protein
SN35N_2390	ENOG4108TZY	GntR Family Transcriptional Regulator
SN35N_2391	ENOG4107UWA	esterase
SN35N_2392	ENOG4107QRI	Phosphoketolase
SN35N_2393	ENOG4105CG5	Glycosyl transferase (Group 1
SN35N_2396	ENOG4105T65	Membrane-associated protein
SN35N_2399	ENOG4108YBP	pseudouridine synthase
SN35N_2400	ENOG4107YZX	Universal stress protein
SN35N_2401	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
SN35N_2402	ENOG4105DF9	Lipoate-protein, ligase
SN35N_2405	ENOG41081I9	integral membrane protein
SN35N_2408	ENOG4105C28	cystathionine
SN35N_2410	ENOG4108MXZ	Esterase
SN35N_2412	ENOG4105C7K	acetolactate synthase
SN35N_2423	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_2428	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SN35N_2429	ENOG4107SUZ	Sodium/hydrogen exchanger family
SN35N_2430	ENOG4105D9R	oxidoreductase
SN35N_2431	ENOG4105EE0	oxidoreductase
SN35N_2432	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
SN35N_2435	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SN35N_2437	ENOG4108TVJ	Nitroreductase
SN35N_2438	ENOG4105CSR	polyphosphate kinase 2
SN35N_2442	ENOG4105CAY	ferredoxin--nadp reductase
SN35N_2443	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
SN35N_2445	ENOG4105E0M	Sulfatase
SN35N_2452	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SN35N_2454	ENOG4105E1F	short-chain dehydrogenase reductase
SN35N_2455	ENOG4105VUF	Transcriptional regulator
SN35N_2459	ENOG4108W76	histidinol phosphate phosphatase hisj family
SN35N_2460	ENOG4107Z2D	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
SN35N_2461	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SN35N_2462	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SN35N_2463	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SN35N_2464	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SN35N_2465	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SN35N_2466	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SN35N_2467	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SN35N_2468	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
SN35N_2469	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SN35N_2470	ENOG4108UW5	maltose o-acetyltransferase
SN35N_2471	ENOG4107TS3	membrane protein, TerC
SN35N_2472	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SN35N_2473	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_2475	ENOG4105C7J	ABC transporter, permease
SN35N_2478	ENOG4105CVG	Homoserine O-transsuccinylase
SN35N_2480	ENOG4105D6E	homoserine dehydrogenase
SN35N_2481	ENOG4105EPR	degv family
SN35N_2482	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
SN35N_2483	ENOG4105CI1	PTS System
SN35N_2484	ENOG4105D5G	Transposase
SN35N_2485	ENOG4105CI1	PTS System
SN35N_2487	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SN35N_2489	ENOG4105C5H	ABC transporter
SN35N_2490	ENOG4106TD9	Diguanylate cyclase
SN35N_2493	ENOG4105EW9	transcriptional regulator AsnC family
SN35N_2494	ENOG4107SN7	NLP P60 protein
SN35N_2498	ENOG41079KZ	Major Facilitator Superfamily
SN35N_2501	ENOG4108UZ3	Transporter
SN35N_2502	ENOG4105VUC	UPF0237 protein
SN35N_2503	ENOG4105CAG	UPF0210 protein
SN35N_2504	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SN35N_2505	ENOG4105BZU	Histidine kinase
SN35N_2506	ENOG4105DR4	Methyltransferase
SN35N_2507	ENOG4105CSC	Glucose uptake protein
SN35N_2508	ENOG4107QYV	phosphohexose isomerase
SN35N_2510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SN35N_2512	ENOG4105BZ1	(ABC) transporter
SN35N_2522	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
SN35N_2527	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SN35N_2546	ENOG4108FPN	Integrase
SN35N_2553	ENOG4108IMY	Transcriptional regulator
SN35N_2607	ENOG4107BJW	polysaccharide deacetylase
SN35N_2610	ENOG4105BZ1	(ABC) transporter
SN35N_2613	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SN35N_2615	ENOG4107S1E	Beta-lactamase
SN35N_2616	ENOG4105DG6	mannose-6-phosphate isomerase
SN35N_2617	ENOG4105F1K	Glutamine amidotransferase
SN35N_2618	ENOG4105DMS	mur ligase
SN35N_2619	ENOG4107104	thymidine kinase
SN35N_2620	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SN35N_2621	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SN35N_2622	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SN35N_2623	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SN35N_2624	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SN35N_2627	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
SN35N_2628	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SN35N_2629	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SN35N_2630	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SN35N_2631	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SN35N_2632	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SN35N_2633	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SN35N_2634	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SN35N_2635	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SN35N_2637	ENOG4105DFF	Rod shape-determining protein mreb
SN35N_2638	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SN35N_2641	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SN35N_2642	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SN35N_2643	ENOG4108UMI	ABC transporter, permease
SN35N_2644	ENOG4105D01	(LipO)protein
SN35N_2648	ENOG4105CPF	Cell wall formation (By similarity)
SN35N_2652	ENOG4107YZX	Universal stress protein
SN35N_2654	ENOG4105D1H	recombination factor protein RarA
SN35N_2655	ENOG4105D9M	gamma-glutamylcysteine synthetase
SN35N_2656	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_2657	ENOG4108IQ3	PTS system
SN35N_2658	ENOG4105ETZ	PTS System
SN35N_2659	ENOG4105F3R	pts system mannose fructose sorbose family iid
SN35N_2661	ENOG4105CG3	alpha amylase, catalytic region
SN35N_2662	ENOG41085FC	arsR family transcriptional regulator
SN35N_2665	ENOG4108WQ8	UPF0637 protein
SN35N_2666	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SN35N_2668	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
SN35N_2670	ENOG4105C3J	Cysteine desulfurase
SN35N_2671	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
SN35N_2672	ENOG4105D9M	gamma-glutamylcysteine synthetase
SN35N_2674	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SN35N_2675	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SN35N_2676	ENOG4105W5Q	DNA repair protein (RadC
SN35N_2677	ENOG4105DFF	Rod shape-determining protein mreb
SN35N_2678	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
SN35N_2681	ENOG4107QMS	site-determining protein
SN35N_2682	ENOG4105E5Q	amino acid AbC transporter
SN35N_2683	ENOG4105CDA	abc transporter atp-binding protein
SN35N_2684	ENOG4108HW3	(ABC) transporter
SN35N_2686	ENOG4105CFH	Aspartokinase
SN35N_2690	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SN35N_2691	ENOG4105CEV	competence damage-inducible protein
SN35N_2692	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SN35N_2693	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SN35N_2694	ENOG4105D48	metallophosphoesterase
SN35N_2695	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SN35N_2696	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SN35N_2700	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SN35N_2701	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SN35N_2702	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SN35N_2703	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SN35N_2704	ENOG4105VIE	preprotein translocase, subunit YajC
SN35N_2705	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SN35N_2706	ENOG4105SFS	phosphoesterase RecJ domain protein
SN35N_2707	ENOG4105C1J	atp-dependent rna helicase
SN35N_2708	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SN35N_2709	ENOG4105VBH	UPF0297 protein
SN35N_2710	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SN35N_2711	ENOG4105VPH	UPF0473 protein
SN35N_2713	ENOG4105C98	muts2 protein
SN35N_2714	ENOG4105K63	Thioredoxin
SN35N_2716	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
SN35N_2717	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SN35N_2720	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
SN35N_2721	ENOG4105CH2	amidohydrolase
SN35N_2722	ENOG4105D8X	mechanosensitive ion channel
SN35N_2726	ENOG4105DC7	peptidase M24
SN35N_2727	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_2730	ENOG4105CDY	transcriptional regulatory protein
SN35N_2739	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SN35N_2741	ENOG4105C85	amino acid
SN35N_2743	ENOG4107R8B	5'-nucleotidase
SN35N_2744	ENOG4105MMD	transcriptional regulator
SN35N_2745	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
SN35N_2747	ENOG4105DQR	SNARE associated Golgi
SN35N_2752	ENOG4108RQ5	Beta-lactamase domain-containing protein
SN35N_2753	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
SN35N_2754	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
SN35N_2756	ENOG4105DPN	Oligoendopeptidase f
SN35N_2759	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SN35N_2760	ENOG4105EMS	pseudouridine synthase
SN35N_2761	ENOG4106N3A	copper homeostasis protein cutc
SN35N_2762	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
SN35N_2765	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SN35N_2767	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
SN35N_2769	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SN35N_2770	ENOG4105CNU	cell division protein FtsK
SN35N_2773	ENOG4108V6E	Cell division protein mraZ
SN35N_2774	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SN35N_2776	ENOG4105CJN	penicillin-binding protein
SN35N_2777	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
SN35N_2778	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SN35N_2779	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
SN35N_2780	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
SN35N_2783	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
SN35N_2784	ENOG41067XK	integral membrane protein
SN35N_2787	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SN35N_2790	ENOG4105DY9	regulatoR
SN35N_2792	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SN35N_2793	ENOG4108YZ4	nudix hydrolase
SN35N_2795	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
SN35N_2796	ENOG4105C3J	Cysteine desulfurase
SN35N_2798	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SN35N_2800	ENOG4107ZYR	domain protein
SN35N_2804	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SN35N_2806	ENOG4105C7H	Helicase, RecD TraA family
SN35N_2807	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SN35N_2808	ENOG41069ER	domain protein
SN35N_2811	ENOG4105CN5	Metallo-Beta-Lactamase
SN35N_2812	ENOG4106EHS	UPF0356 protein
SN35N_2814	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SN35N_2815	ENOG4107RUY	(E1 component), alpha subunit
SN35N_2819	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SN35N_2820	ENOG4105WBI	UPF0223 protein
SN35N_2821	ENOG4105ECY	inositol monophosphatase
SN35N_2822	ENOG4105CI3	gtp-binding protein typa
SN35N_2826	ENOG4105CNI	cell division protein FtsW
SN35N_2827	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
SN35N_2828	ENOG4105WUC	UPF0298 protein
SN35N_2829	ENOG4106H78	methyltransferase
SN35N_2830	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SN35N_2831	ENOG41063PX	domain protein
SN35N_2832	ENOG4105KQC	Competence protein
SN35N_2833	ENOG4108UK2	deaminase
SN35N_2834	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
SN35N_2835	ENOG4105TQK	DNA polymerase iii, delta' subunit
SN35N_2836	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
SN35N_2837	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SN35N_2838	ENOG4105C6X	Major Facilitator
SN35N_2840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SN35N_2843	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SN35N_2844	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
SN35N_2845	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SN35N_2846	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SN35N_2850	ENOG4105EAD	ABC transporter
SN35N_2851	ENOG4105CDA	abc transporter atp-binding protein
SN35N_2852	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SN35N_2854	ENOG4108QV3	biosynthesis protein
SN35N_2856	ENOG4108IAJ	Nad-dependent epimerase dehydratase
SN35N_2858	ENOG4105CPK	Glycosyl transferase (Group 1
SN35N_2861	ENOG4108RYC	glycosyltransferase
SN35N_2863	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
SN35N_2864	ENOG4105DM4	PTS System
SN35N_2865	ENOG4105DE4	1-phosphofructokinase
SN35N_2866	ENOG4105E98	transcriptional regulator DeoR family
SN35N_2867	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SN35N_2869	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SN35N_2870	ENOG4108IXY	short-chain dehydrogenase reductase
SN35N_2871	ENOG41067VP	Protein of unknown function (DUF1049)
SN35N_2872	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SN35N_2873	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SN35N_2876	ENOG4105K8R	UPF0145 protein
SN35N_2882	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SN35N_2936	ENOG4105F9F	transposase
SN35N_2941	ENOG4108KGH	TRANSCRIPTIONal
SN35N_2943	ENOG4105CKK	Glycosyl transferase, family 2
SN35N_2946	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
SN35N_2948	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
SN35N_2950	ENOG4105VPS	UPF0291 protein
SN35N_2951	ENOG4105VXM	UPF0154 protein
SN35N_2952	ENOG4105F6E	Acyl-transferase
SN35N_2953	ENOG41060K3	Methyltransferase
SN35N_2954	ENOG4105VC4	domain protein
SN35N_2955	ENOG4105C5I	Dehydrogenase
SN35N_2958	ENOG4105CE9	30S ribosomal protein S2
SN35N_2959	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
SN35N_2960	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
SN35N_2961	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SN35N_2962	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SN35N_2963	ENOG4105KNE	Phosphatidate cytidylyltransferase
SN35N_2964	ENOG4105DZP	Membrane-associated zinc metalloprotease
SN35N_2965	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SN35N_2966	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SN35N_2967	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SN35N_2968	ENOG4105CHV	Transcription elongation factor NusA
SN35N_2969	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
SN35N_2971	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
SN35N_2972	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SN35N_2973	ENOG4105EMV	Major Facilitator
SN35N_2974	ENOG4105EMV	Major Facilitator
SN35N_2975	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SN35N_2977	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SN35N_2980	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SN35N_2981	ENOG4105DTN	riboflavin biosynthesis protein ribF
SN35N_2982	ENOG4107FQX	Alpha-acetolactate decarboxylase
SN35N_2983	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
SN35N_2984	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SN35N_2985	ENOG4105CFG	Acts as a chaperone (By similarity)
SN35N_2986	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SN35N_2987	ENOG4105FQP	Beta-lactamase
SN35N_2989	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
SN35N_2990	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
SN35N_2991	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
SN35N_2992	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
SN35N_2993	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SN35N_2996	ENOG4108VX5	3-methyladenine DNA glycosylase
SN35N_2997	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SN35N_2998	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SN35N_3000	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SN35N_3001	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
SN35N_3002	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SN35N_3004	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SN35N_3005	ENOG4105CUT	histidyl-tRNA synthetase
SN35N_3006	ENOG4105C9M	aspartyl-trna synthetase
SN35N_3007	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SN35N_3008	ENOG4107AYK	membrAne
SN35N_3010	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
SN35N_3011	ENOG4105CHR	reductase
SN35N_3012	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
SN35N_3013	ENOG4105VCC	30S ribosomal protein S21
SN35N_3014	ENOG4105KTH	gatB Yqey
SN35N_3015	ENOG4105C9A	Phoh family
SN35N_3016	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SN35N_3017	ENOG4107YR5	Diacylglycerol kinase
SN35N_3018	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SN35N_3019	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
SN35N_3020	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
SN35N_3021	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
SN35N_3022	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SN35N_3023	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SN35N_3024	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
SN35N_3025	ENOG4105CZV	ABC transporter
SN35N_3029	ENOG4105CJ1	ABC, transporter
SN35N_3034	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SN35N_3036	ENOG4108M15	ABC transporter
SN35N_3038	ENOG4108ZGX	Histidine kinase
SN35N_3039	ENOG4108S01	response regulator
SN35N_3040	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_3042	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
SN35N_3043	ENOG4108W5M	transcriptional regulator
SN35N_3049	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SN35N_3054	ENOG4105DQ6	Transposase
SN35N_3066	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
SN35N_3068	ENOG4105E98	transcriptional regulator DeoR family
SN35N_3069	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SN35N_3071	ENOG4107PP3	Acetylornithine deacetylase
SN35N_3073	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SN35N_3075	ENOG4105C59	p-type ATPase
SN35N_3080	ENOG41082F9	transcriptional regulator
SN35N_3089	ENOG4105EGD	dinuclear metal center protein, YbgI family
SN35N_3090	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
SN35N_3091	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SN35N_3093	ENOG4105C0B	DNA polymerase III (alpha subunit)
SN35N_3094	ENOG4105CTQ	phosphohexokinase
SN35N_3095	ENOG4105CA9	Pyruvate kinase
SN35N_3097	ENOG4105QNR	S1 RNA binding domain protein
SN35N_3098	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SN35N_3100	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
SN35N_3101	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
SN35N_3102	ENOG4105FE9	pseudouridine synthase
SN35N_3103	ENOG4108SAX	Membrane
SN35N_3105	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SN35N_3107	ENOG4105CAT	Cytidine monophosphate kinase
SN35N_3108	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SN35N_3109	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SN35N_3111	ENOG41068YB	TPR repeat-containing protein
SN35N_3112	ENOG4108HCJ	Hydrolase
SN35N_3113	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SN35N_3114	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SN35N_3116	ENOG4105C5H	ABC transporter
SN35N_3117	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
SN35N_3118	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
SN35N_3119	ENOG4108RCR	degv family
SN35N_3120	ENOG41090WU	lipolytic protein G-D-S-L family
SN35N_3121	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
SN35N_3122	ENOG4105VSD	UPF0346 protein
SN35N_3127	ENOG4107RSM	transcriptional regulator
SN35N_3129	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
SN35N_3130	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SN35N_3131	ENOG4105C79	DNA protecting protein DprA
SN35N_3132	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SN35N_3133	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
SN35N_3134	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SN35N_3135	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SN35N_3136	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SN35N_3138	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SN35N_3139	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SN35N_3141	ENOG4105DND	Transcriptional regulator
SN35N_3142	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
SN35N_3143	ENOG4105E0X	reductase
SN35N_3144	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SN35N_5006	ENOG4107QJE	Chromosome Partitioning Protein
SN35N_5009	ENOG4105ETE	Transcriptional regulator (LacI family
SN35N_5017	ENOG4108IYH	Dna topoisomerase
SN35N_5020	ENOG4105DQ6	Transposase
SN35N_5024	ENOG4105NA0	Transcriptional regulator
SN35N_5026	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SN35N_6003	ENOG4105D5G	Transposase
SN35N_6006	ENOG4105D5G	Transposase
SN35N_6009	ENOG4105F9F	transposase
SN35N_6011	ENOG4105K64	Glycosyl transferase, family 2
SN35N_6016	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
SN35N_6018	ENOG4105D3Q	Sugar transferase
SN35N_6020	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
SN35N_6021	ENOG4105DQ6	Transposase
SN35N_6023	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
SN35N_6024	ENOG4107YJ4	chain length determinant protein
SN35N_6026	ENOG4107XU6	Glycosyl transferase (Group 1
SN35N_6028	ENOG4105D5G	Transposase
SN35N_6029	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SN35N_6039	ENOG4107QJE	Chromosome Partitioning Protein
SN35N_6043	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
SN35N_7006	ENOG41068KG	domain protein
SN35N_7007	ENOG4105F9F	transposase
SN35N_7026	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SN35N_7031	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SN35N_7039	ENOG4105DQ6	Transposase
SN35N_7043	ENOG4105NA0	Transcriptional regulator
SN35N_7045	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SN35N_7051	ENOG4105EST	Metal Dependent Phosphohydrolase
SN35N_7053	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SN35N_7054	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SN35N_7055	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SN35N_7059	ENOG4108JYZ	YitT family