locus-tag	class	description
SN35N_0005	COG1846	Transcriptional regulator
SN35N_0008	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SN35N_0010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SN35N_0012	COG1620	l-lactate permease
SN35N_0015	COG1113	amino acid transport
SN35N_0026	COG1307	EDD domain protein, DegV family
SN35N_0029	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SN35N_0030	COG1131	(ABC) transporter
SN35N_0036	COG5646	InterPro IPR014922
SN35N_0038	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SN35N_0039	COG0505	Belongs to the CarA family
SN35N_0040	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SN35N_0041	COG0564	pseudouridine synthase activity
SN35N_0042	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SN35N_0043	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SN35N_0046	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SN35N_0053	COG1619	proteins homologs of microcin C7 resistance protein MccF
SN35N_0060	COG1073	alpha beta
SN35N_0061	COG0477	Major facilitator Superfamily
SN35N_0063	COG0116	Belongs to the methyltransferase superfamily
SN35N_0064	COG3599	regulation of cell shape
SN35N_0065	COG4474	Belongs to the UPF0398 family
SN35N_0066	COG3331	DNA recombination
SN35N_0069	COG1840	ABC-type Fe3 transport system, periplasmic component
SN35N_0071	COG1177	transmembrane transport
SN35N_0073	COG1464	Belongs to the NlpA lipoprotein family
SN35N_0074	COG2011	ABC-type metal ion transport system permease component
SN35N_0075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SN35N_0077	COG0017	Asparaginyl-tRNA synthetase
SN35N_0080	COG1199	ATP-dependent helicase activity
SN35N_0080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SN35N_0085	COG1304	FMN binding
SN35N_0086	COG2017	converts alpha-aldose to the beta-anomer
SN35N_0087	COG2017	converts alpha-aldose to the beta-anomer
SN35N_0091	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SN35N_0091	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SN35N_0092	COG0561	phosphatase activity
SN35N_0093	COG0531	amino acid
SN35N_0100	COG1942	4-Oxalocrotonate Tautomerase
SN35N_0103	COG3237	CsbD-like
SN35N_0105	COG2801	Transposase and inactivated derivatives
SN35N_0106	COG2261	transglycosylase associated protein
SN35N_0109	COG1597	lipid kinase activity
SN35N_0110	COG3152	Membrane
SN35N_0112	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
SN35N_0115	COG3397	chitin binding
SN35N_0116	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SN35N_0119	COG3328	transposase activity
SN35N_0126	COG0477	Major facilitator Superfamily
SN35N_0128	COG1162	GTPase activity
SN35N_0129	COG1607	acyl-coa hydrolase
SN35N_0130	COG0583	DNA-binding transcription factor activity
SN35N_0131	COG1811	Na channel or pump
SN35N_0133	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SN35N_0136	COG0439	Biotin carboxylase
SN35N_0139	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SN35N_0140	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_0141	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SN35N_0142	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SN35N_0143	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SN35N_0144	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SN35N_0146	COG0300	oxidoreductase activity
SN35N_0148	COG1063	alcohol dehydrogenase
SN35N_0151	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SN35N_0154	COG0159	tryptophan synthase activity
SN35N_0155	COG0133	tryptophan synthase activity
SN35N_0156	COG0135	phosphoribosylanthranilate isomerase activity
SN35N_0157	COG0134	indole-3-glycerol-phosphate synthase activity
SN35N_0158	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SN35N_0159	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SN35N_0159	COG0512	Glutamine amidotransferase of anthranilate synthase
SN35N_0162	COG1131	(ABC) transporter
SN35N_0166	COG0335	large ribosomal subunit rRNA binding
SN35N_0167	COG0336	Belongs to the RNA methyltransferase TrmD family
SN35N_0168	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SN35N_0169	COG1837	Belongs to the UPF0109 family
SN35N_0170	COG0228	four-way junction DNA binding
SN35N_0171	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SN35N_0172	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SN35N_0173	COG0552	protein localization to endoplasmic reticulum
SN35N_0174	COG1196	nuclear chromosome segregation
SN35N_0175	COG0571	ribonuclease III activity
SN35N_0176	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SN35N_0177	COG0416	fatty acid biosynthetic process
SN35N_0178	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SN35N_0179	COG1461	Dihydroxyacetone kinase
SN35N_0180	COG1302	Protein conserved in bacteria
SN35N_0181	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SN35N_0182	COG1564	THIamine pyrophosphokinase
SN35N_0183	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SN35N_0184	COG1162	GTPase activity
SN35N_0185	COG0515	serine threonine protein kinase
SN35N_0185	COG2815	serine threonine protein kinase
SN35N_0186	COG0631	protein serine/threonine phosphatase activity
SN35N_0187	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SN35N_0187	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SN35N_0188	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SN35N_0189	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SN35N_0190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SN35N_0191	COG1758	RNA polymerase activity
SN35N_0192	COG0194	GDP metabolic process
SN35N_0194	COG1174	glycine betaine transport
SN35N_0195	COG1732	Glycine betaine
SN35N_0198	COG0497	DNA recombination
SN35N_0199	COG1438	arginine binding
SN35N_0200	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SN35N_0201	COG0142	geranyltranstransferase activity
SN35N_0202	COG1722	exodeoxyribonuclease VII activity
SN35N_0203	COG1570	exodeoxyribonuclease VII activity
SN35N_0204	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SN35N_0205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SN35N_0206	COG1302	Protein conserved in bacteria
SN35N_0207	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SN35N_0208	COG0006	proline dipeptidase activity
SN35N_0209	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SN35N_0211	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SN35N_0221	COG0789	Transcriptional regulator
SN35N_0222	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SN35N_0223	COG0584	glycerophosphoryl diester phosphodiesterase
SN35N_0227	COG1940	carbohydrate kinase activity
SN35N_0229	COG0457	Tetratricopeptide repeat
SN35N_0229	COG0705	Rhomboid family
SN35N_0230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SN35N_0231	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SN35N_0232	COG0768	penicillin binding
SN35N_0234	COG4841	protein insertion into membrane
SN35N_0237	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SN35N_0238	COG0572	uridine kinase
SN35N_0239	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SN35N_0240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SN35N_0240	COG0072	phenylalanine-tRNA ligase activity
SN35N_0241	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SN35N_0242	COG1733	regulation of RNA biosynthetic process
SN35N_0244	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SN35N_0245	COG1254	Belongs to the acylphosphatase family
SN35N_0246	COG0706	membrane insertase activity
SN35N_0249	COG0419	ATPase involved in DNA repair
SN35N_0251	COG5002	protein histidine kinase activity
SN35N_0252	COG0745	RESPONSE REGULATOR receiver
SN35N_0253	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SN35N_0254	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SN35N_0257	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SN35N_0259	COG1323	Belongs to the UPF0348 family
SN35N_0260	COG2226	methyltransferase
SN35N_0261	COG0799	negative regulation of ribosome biogenesis
SN35N_0262	COG1713	HD superfamily hydrolase involved in NAD metabolism
SN35N_0263	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SN35N_0264	COG1534	Rna-binding protein
SN35N_0265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SN35N_0268	COG1215	transferase activity, transferring glycosyl groups
SN35N_0270	COG1733	regulation of RNA biosynthetic process
SN35N_0271	COG0604	alcohol dehydrogenase
SN35N_0272	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SN35N_0274	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SN35N_0275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SN35N_0276	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SN35N_0277	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SN35N_0278	COG1484	DNA-dependent DNA replication
SN35N_0279	COG3611	Membrane attachment protein
SN35N_0280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SN35N_0281	COG0237	dephospho-CoA kinase activity
SN35N_0282	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SN35N_0283	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SN35N_0283	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SN35N_0286	COG2151	metal-sulfur cluster biosynthetic enzyme
SN35N_0287	COG0719	Fe-S assembly protein
SN35N_0289	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SN35N_0290	COG0719	Fe-S assembly protein
SN35N_0295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SN35N_0296	COG1674	ftsk spoiiie
SN35N_0297	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SN35N_0299	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SN35N_0300	COG0510	thiamine kinase activity
SN35N_0301	COG4473	ABC transporter
SN35N_0302	COG1131	(ABC) transporter
SN35N_0303	COG0537	adenosine 5'-monophosphoramidase activity
SN35N_0305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SN35N_0311	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_0313	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SN35N_0316	COG1309	transcriptional regulator
SN35N_0321	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SN35N_0322	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SN35N_0322	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SN35N_0323	COG0307	riboflavin synthase, alpha
SN35N_0324	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SN35N_0324	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SN35N_0329	COG0463	Glycosyl transferase, family 2
SN35N_0332	COG3976	FMN-binding domain protein
SN35N_0332	COG1053	succinate dehydrogenase
SN35N_0332	COG0431	NADPH-dependent FMN reductase
SN35N_0334	COG0583	DNA-binding transcription factor activity
SN35N_0337	COG3481	metal-dependent phosphohydrolase, HD sub domain
SN35N_0338	COG4717	serine-type aminopeptidase activity
SN35N_0339	COG0420	3'-5' exonuclease activity
SN35N_0340	COG3679	Belongs to the UPF0342 family
SN35N_0341	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SN35N_0343	COG1438	arginine binding
SN35N_0344	COG0436	Aminotransferase
SN35N_0346	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SN35N_0347	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SN35N_0348	COG1376	ErfK ybiS ycfS ynhG family protein
SN35N_0350	COG2723	6-phospho-beta-galactosidase activity
SN35N_0351	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_0352	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_0353	COG1447	Phosphotransferase system cellobiose-specific component IIA
SN35N_0357	COG0577	efflux transmembrane transporter activity
SN35N_0357	COG1136	(ABC) transporter
SN35N_0359	COG0018	arginyl-trna synthetase
SN35N_0360	COG2153	protein acetylation
SN35N_0362	COG0534	Mate efflux family protein
SN35N_0363	COG3273	potassium ion transport
SN35N_0363	COG0471	metal ion transport
SN35N_0365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SN35N_0366	COG0529	Catalyzes the synthesis of activated sulfate
SN35N_0367	COG2046	Belongs to the sulfate adenylyltransferase family
SN35N_0369	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SN35N_0370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SN35N_0370	COG0646	methionine synthase
SN35N_0392	COG0740	serine-type endopeptidase activity
SN35N_0425	COG1396	sequence-specific DNA binding
SN35N_0429	COG1002	Type II restriction enzyme, methylase subunits
SN35N_0431	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SN35N_0434	COG1846	Transcriptional regulator
SN35N_0438	COG3279	Response regulator of the LytR AlgR family
SN35N_0442	COG0561	phosphatase activity
SN35N_0443	COG0697	spore germination
SN35N_0445	COG0789	Transcriptional regulator
SN35N_0446	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SN35N_0452	COG1511	domain protein
SN35N_0452	COG1511	domain protein
SN35N_0453	COG1970	mechanosensitive ion channel activity
SN35N_0454	COG1428	Deoxynucleoside kinase
SN35N_0455	COG0584	glycerophosphoryl diester phosphodiesterase
SN35N_0457	COG0395	ABC-type sugar transport system, permease component
SN35N_0458	COG1175	transmembrane transport
SN35N_0459	COG3842	ATPase activity
SN35N_0461	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SN35N_0462	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SN35N_0463	COG1187	pseudouridine synthase activity
SN35N_0464	COG2244	polysaccharide biosynthetic process
SN35N_0465	COG0495	leucyl-tRNA aminoacylation
SN35N_0467	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SN35N_0470	COG0438	transferase activity, transferring glycosyl groups
SN35N_0474	COG0477	Major facilitator Superfamily
SN35N_0475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SN35N_0477	COG0438	transferase activity, transferring glycosyl groups
SN35N_0478	COG2040	homocysteine
SN35N_0479	COG0833	amino acid
SN35N_0481	COG1914	H( )-stimulated, divalent metal cation uptake system
SN35N_0483	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SN35N_0487	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SN35N_0489	COG1368	sulfuric ester hydrolase activity
SN35N_0490	COG4703	Protein of unknown function (DUF1797)
SN35N_0491	COG0436	Aminotransferase
SN35N_0492	COG1686	Belongs to the peptidase S11 family
SN35N_0494	COG0438	transferase activity, transferring glycosyl groups
SN35N_0495	COG0438	transferase activity, transferring glycosyl groups
SN35N_0499	COG0542	response to heat
SN35N_0500	COG0582	viral genome integration into host DNA
SN35N_0502	COG4608	Belongs to the ABC transporter superfamily
SN35N_0503	COG0444	Belongs to the ABC transporter superfamily
SN35N_0504	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SN35N_0505	COG0601	transmembrane transport
SN35N_0506	COG4166	transmembrane transport
SN35N_0512	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SN35N_0513	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SN35N_0514	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SN35N_0515	COG1070	Carbohydrate kinase
SN35N_0516	COG2610	gluconate transmembrane transporter activity
SN35N_0517	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SN35N_0518	COG0628	permease
SN35N_0525	COG3557	Belongs to the UPF0374 family
SN35N_0526	COG2137	regulation of response to DNA damage stimulus
SN35N_0533	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SN35N_0541	COG0562	UDP-galactopyranose mutase
SN35N_0546	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SN35N_0547	COG2244	polysaccharide biosynthetic process
SN35N_0549	COG1216	Glycosyl transferase, family 2
SN35N_0553	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SN35N_0554	COG4464	protein tyrosine phosphatase activity
SN35N_0555	COG0489	protein tyrosine kinase activity
SN35N_0557	COG0582	viral genome integration into host DNA
SN35N_0559	COG1091	dTDP-4-dehydrorhamnose reductase activity
SN35N_0560	COG1088	dTDP-glucose 4,6-dehydratase activity
SN35N_0562	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SN35N_0567	COG0110	maltose O-acetyltransferase activity
SN35N_0568	COG1215	transferase activity, transferring glycosyl groups
SN35N_0568	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SN35N_0575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_0577	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SN35N_0579	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SN35N_0580	COG2801	Transposase and inactivated derivatives
SN35N_0585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_0587	COG0513	Belongs to the DEAD box helicase family
SN35N_0588	COG0673	inositol 2-dehydrogenase activity
SN35N_0589	COG1278	Cold shock
SN35N_0592	COG1737	Transcriptional regulator
SN35N_0594	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_0597	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SN35N_0598	COG1597	lipid kinase activity
SN35N_0599	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SN35N_0600	COG0154	amidase activity
SN35N_0601	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SN35N_0602	COG4851	CamS sex pheromone cAM373 precursor
SN35N_0603	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SN35N_0605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SN35N_0606	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SN35N_0607	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SN35N_0608	COG1705	Flagellar rod assembly protein muramidase FlgJ
SN35N_0611	COG0142	geranyltranstransferase activity
SN35N_0613	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SN35N_0614	COG4988	ABC transporter
SN35N_0615	COG1294	oxidase, subunit
SN35N_0616	COG1271	oxidase subunit
SN35N_0619	COG4684	Psort location CytoplasmicMembrane, score
SN35N_0620	COG0531	amino acid
SN35N_0622	COG0281	malic enzyme
SN35N_0624	COG0583	DNA-binding transcription factor activity
SN35N_0626	COG1053	succinate dehydrogenase
SN35N_0627	COG0114	fumarate hydratase activity
SN35N_0635	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_0638	COG3052	prosthetic group binding
SN35N_0642	COG0471	metal ion transport
SN35N_0643	COG0039	L-malate dehydrogenase activity
SN35N_0645	COG0803	Belongs to the bacterial solute-binding protein 9 family
SN35N_0646	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SN35N_0647	COG1121	(ABC) transporter
SN35N_0648	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SN35N_0649	COG1917	Cupin 2, conserved barrel domain protein
SN35N_0649	COG4977	sequence-specific DNA binding
SN35N_0650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SN35N_0652	COG2151	metal-sulfur cluster biosynthetic enzyme
SN35N_0653	COG0471	metal ion transport
SN35N_0654	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SN35N_0655	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SN35N_0656	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SN35N_0657	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SN35N_0661	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SN35N_0662	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SN35N_0663	COG0101	tRNA pseudouridine synthase activity
SN35N_0665	COG1122	ATPase activity
SN35N_0666	COG1122	ATPase activity
SN35N_0668	COG4939	FMN-binding domain protein
SN35N_0673	COG0203	ribosomal protein L17
SN35N_0674	COG0202	RNA polymerase activity
SN35N_0675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SN35N_0676	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SN35N_0677	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SN35N_0678	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SN35N_0679	COG0563	adenylate kinase activity
SN35N_0681	COG0200	Binds to the 23S rRNA
SN35N_0682	COG1841	ribosomal large subunit assembly
SN35N_0683	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SN35N_0684	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SN35N_0685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SN35N_0686	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SN35N_0687	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SN35N_0688	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SN35N_0689	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SN35N_0690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SN35N_0691	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SN35N_0692	COG0255	Belongs to the universal ribosomal protein uL29 family
SN35N_0693	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SN35N_0694	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SN35N_0695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SN35N_0696	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SN35N_0697	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SN35N_0698	COG0089	rRNA binding
SN35N_0699	COG0088	Forms part of the polypeptide exit tunnel
SN35N_0700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SN35N_0701	COG0051	transcription antitermination factor activity, RNA binding
SN35N_0703	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SN35N_0704	COG0049	tRNA binding
SN35N_0705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SN35N_0707	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SN35N_0708	COG0085	RNA polymerase activity
SN35N_0710	COG0542	response to heat
SN35N_0711	COG4463	regulation of RNA biosynthetic process
SN35N_0712	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SN35N_0713	COG1428	Deoxynucleoside kinase
SN35N_0715	COG0833	amino acid
SN35N_0716	COG0028	Belongs to the TPP enzyme family
SN35N_0717	COG1959	2 iron, 2 sulfur cluster binding
SN35N_0721	COG1316	TRANSCRIPTIONal
SN35N_0723	COG2966	Psort location CytoplasmicMembrane, score
SN35N_0724	COG1278	Cold shock
SN35N_0728	COG2814	Major facilitator Superfamily
SN35N_0735	COG0367	asparagine synthase
SN35N_0736	COG0527	aspartate kinase activity
SN35N_0737	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SN35N_0747	COG0640	Transcriptional regulator
SN35N_0748	COG0564	pseudouridine synthase activity
SN35N_0749	COG0514	ATP-dependent DNA helicase (RecQ)
SN35N_0753	COG4690	dipeptidase activity
SN35N_0754	COG2502	aspartate--ammonia ligase
SN35N_0755	COG0017	Asparaginyl-tRNA synthetase
SN35N_0756	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SN35N_0758	COG1053	succinate dehydrogenase
SN35N_0759	COG0583	DNA-binding transcription factor activity
SN35N_0762	COG0572	uridine kinase
SN35N_0775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SN35N_0776	COG0308	aminopeptidase N
SN35N_0782	COG1302	Protein conserved in bacteria
SN35N_0785	COG2261	transglycosylase associated protein
SN35N_0786	COG2755	lipolytic protein G-D-S-L family
SN35N_0786	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SN35N_0789	COG1266	CAAX protease self-immunity
SN35N_0791	COG1396	sequence-specific DNA binding
SN35N_0793	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SN35N_0793	COG0519	Catalyzes the synthesis of GMP from XMP
SN35N_0794	COG1072	(Pantothenic acid kinase))
SN35N_0795	COG2070	2-Nitropropane dioxygenase
SN35N_0796	COG3973	AAA domain
SN35N_0797	COG0586	Pfam SNARE associated Golgi protein
SN35N_0798	COG0456	acetyltransferase
SN35N_0798	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SN35N_0799	COG0569	domain protein
SN35N_0799	COG0475	glutathione-regulated potassium exporter activity
SN35N_0800	COG0588	phosphoglycerate mutase activity
SN35N_0802	COG3328	transposase activity
SN35N_0804	COG2076	Multidrug Resistance protein
SN35N_0806	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SN35N_0812	COG1846	Transcriptional regulator
SN35N_0814	COG0531	amino acid
SN35N_0815	COG3394	polysaccharide catabolic process
SN35N_0816	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_0816	COG1263	PTS System
SN35N_0818	COG2190	(PTS) system
SN35N_0818	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_0818	COG1263	PTS System
SN35N_0822	COG0765	amino acid transport
SN35N_0823	COG0765	amino acid transport
SN35N_0824	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SN35N_0828	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SN35N_0829	COG0436	Aminotransferase
SN35N_0830	COG0546	phosphoglycolate phosphatase activity
SN35N_0835	COG2801	Transposase and inactivated derivatives
SN35N_0836	COG0735	belongs to the Fur family
SN35N_0837	COG0194	GDP metabolic process
SN35N_0842	COG0531	amino acid
SN35N_0845	COG2936	dipeptidyl-peptidase activity
SN35N_0846	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SN35N_0846	COG2755	lipolytic protein G-D-S-L family
SN35N_0848	COG2267	carboxylic ester hydrolase activity
SN35N_0849	COG0028	Belongs to the TPP enzyme family
SN35N_0850	COG0196	riboflavin kinase activity
SN35N_0851	COG0028	Belongs to the TPP enzyme family
SN35N_0852	COG2252	PERMEase
SN35N_0855	COG3475	LICD family
SN35N_0857	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SN35N_0858	COG0248	Ppx GppA phosphatase
SN35N_0858	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SN35N_0859	COG0477	Major facilitator Superfamily
SN35N_0862	COG1393	Belongs to the ArsC family
SN35N_0864	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SN35N_0868	COG0778	Nitroreductase
SN35N_0871	COG2017	converts alpha-aldose to the beta-anomer
SN35N_0873	COG0561	phosphatase activity
SN35N_0875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SN35N_0876	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SN35N_0881	COG0025	NhaP-type Na H and K H
SN35N_0882	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SN35N_0884	COG0708	Exodeoxyribonuclease III
SN35N_0887	COG0802	atpase or kinase
SN35N_0888	COG0280	phosphate acetyltransferase
SN35N_0889	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SN35N_0890	COG0561	phosphatase activity
SN35N_0892	COG1126	abc transporter atp-binding protein
SN35N_0893	COG0765	amino acid transport
SN35N_0896	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SN35N_0897	COG0557	exoribonuclease II activity
SN35N_0899	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SN35N_0900	COG0038	chloride channel
SN35N_0903	COG0148	phosphopyruvate hydratase activity
SN35N_0904	COG0149	triose-phosphate isomerase activity
SN35N_0905	COG0126	phosphoglycerate kinase activity
SN35N_0907	COG2390	Transcriptional regulator
SN35N_0908	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SN35N_0909	COG0740	serine-type endopeptidase activity
SN35N_0910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SN35N_0912	COG1481	regulation of sporulation
SN35N_0914	COG1660	Displays ATPase and GTPase activities
SN35N_0916	COG0165	Argininosuccinate lyase
SN35N_0917	COG0137	argininosuccinate synthase activity
SN35N_0918	COG1854	S-ribosylhomocysteine lyase activity
SN35N_0919	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SN35N_0920	COG0556	nucleotide-excision repair
SN35N_0922	COG2814	Major facilitator Superfamily
SN35N_0924	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_0926	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SN35N_0928	COG2323	membrane
SN35N_0929	COG0492	ferredoxin-NADP+ reductase activity
SN35N_0930	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_0933	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SN35N_0934	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SN35N_0935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SN35N_0936	COG1950	PFAM Membrane protein of
SN35N_0937	COG1983	PspC domain protein
SN35N_0938	COG0704	Plays a role in the regulation of phosphate uptake
SN35N_0939	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SN35N_0940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SN35N_0941	COG0581	inorganic phosphate transmembrane transporter activity
SN35N_0942	COG0573	inorganic phosphate transmembrane transporter activity
SN35N_0943	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SN35N_0944	COG5002	protein histidine kinase activity
SN35N_0945	COG0745	RESPONSE REGULATOR receiver
SN35N_0947	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SN35N_0948	COG0653	protein targeting
SN35N_0951	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SN35N_0952	COG1739	Uncharacterized protein family UPF0029
SN35N_0953	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SN35N_0954	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SN35N_0955	COG0531	amino acid
SN35N_0956	COG0459	protein refolding
SN35N_0957	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SN35N_0959	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SN35N_0960	COG0488	(ABC) transporter
SN35N_0961	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SN35N_0962	COG0456	acetyltransferase
SN35N_0963	COG0456	acetyltransferase
SN35N_0964	COG1214	PFAM Peptidase M22, glycoprotease
SN35N_0966	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SN35N_0968	COG3639	organic phosphonate transmembrane transporter activity
SN35N_0969	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SN35N_0970	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SN35N_0971	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SN35N_0974	COG4467	Involved in initiation control of chromosome replication
SN35N_0975	COG0470	DNA polymerase III
SN35N_0976	COG3870	Protein conserved in bacteria
SN35N_0977	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SN35N_0979	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SN35N_0980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SN35N_0981	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SN35N_0983	COG2813	Specifically methylates the guanine in position
SN35N_0984	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SN35N_0985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SN35N_0987	COG1611	Belongs to the LOG family
SN35N_1016	COG1783	phage Terminase large subunit
SN35N_1056	COG0222	ribosome binding
SN35N_1057	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SN35N_1058	COG0081	regulation of translation
SN35N_1059	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SN35N_1061	COG0250	Participates in transcription elongation, termination and antitermination
SN35N_1063	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SN35N_1066	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SN35N_1067	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SN35N_1068	COG0215	cysteine-tRNA ligase activity
SN35N_1069	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SN35N_1071	COG4956	integral membrane protein (PIN domain superfamily)
SN35N_1073	COG0756	dUTP diphosphatase activity
SN35N_1075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SN35N_1077	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SN35N_1077	COG5549	protein import
SN35N_1079	COG0588	phosphoglycerate mutase activity
SN35N_1080	COG0697	spore germination
SN35N_1082	COG1316	TRANSCRIPTIONal
SN35N_1083	COG0825	malonyl-CoA metabolic process
SN35N_1085	COG0439	Biotin carboxylase
SN35N_1087	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SN35N_1088	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1088	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1089	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1089	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SN35N_1090	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SN35N_1092	COG3716	PTS system mannose fructose sorbose family IID component
SN35N_1093	COG3715	PTS system
SN35N_1096	COG0083	homoserine kinase activity
SN35N_1097	COG0460	homoserine dehydrogenase
SN35N_1098	COG3091	SprT-like family
SN35N_1099	COG2183	response to ionizing radiation
SN35N_1102	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SN35N_1103	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SN35N_1107	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SN35N_1116	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_1118	COG0531	amino acid
SN35N_1131	COG0582	viral genome integration into host DNA
SN35N_1133	COG3104	oligopeptide transport
SN35N_1134	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SN35N_1135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SN35N_1136	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SN35N_1139	COG0037	tRNA processing
SN35N_1140	COG1098	S1 RNA binding domain
SN35N_1142	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SN35N_1143	COG2244	polysaccharide biosynthetic process
SN35N_1144	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SN35N_1145	COG0193	aminoacyl-tRNA hydrolase activity
SN35N_1146	COG0039	L-malate dehydrogenase activity
SN35N_1150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SN35N_1151	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SN35N_1152	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SN35N_1153	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SN35N_1154	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SN35N_1155	COG0505	Belongs to the CarA family
SN35N_1156	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SN35N_1160	COG3158	transport of potassium into the cell
SN35N_1161	COG2337	Toxic component of a toxin-antitoxin (TA) module
SN35N_1162	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SN35N_1163	COG0736	holo-[acyl-carrier-protein] synthase activity
SN35N_1165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SN35N_1167	COG0501	Belongs to the peptidase M48B family
SN35N_1168	COG1704	LemA family
SN35N_1169	COG3764	Sortase (surface protein transpeptidase)
SN35N_1171	COG0254	rRNA binding
SN35N_1172	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SN35N_1173	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SN35N_1176	COG1760	l-serine dehydratase
SN35N_1177	COG1760	l-serine dehydratase
SN35N_1178	COG0814	amino acid
SN35N_1179	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SN35N_1180	COG0504	CTP synthase activity
SN35N_1181	COG3343	RNA polymerase activity
SN35N_1183	COG0095	Lipoate-protein ligase
SN35N_1184	COG1078	dGTPase activity
SN35N_1188	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SN35N_1190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SN35N_1191	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SN35N_1192	COG1321	iron dependent repressor
SN35N_1192	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SN35N_1193	COG1121	(ABC) transporter
SN35N_1194	COG1073	alpha beta
SN35N_1195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SN35N_1196	COG4466	Protein conserved in bacteria
SN35N_1197	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SN35N_1198	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SN35N_1199	COG0084	hydrolase, TatD family'
SN35N_1200	COG2814	Major facilitator Superfamily
SN35N_1201	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SN35N_1201	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SN35N_1204	COG1801	Protein of unknown function DUF72
SN35N_1205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SN35N_1209	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SN35N_1211	COG1940	carbohydrate kinase activity
SN35N_1212	COG2723	6-phospho-beta-galactosidase activity
SN35N_1213	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_1216	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_1217	COG2188	Transcriptional regulator
SN35N_1218	COG0180	Tryptophanyl-tRNA synthetase
SN35N_1219	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SN35N_1220	COG3973	AAA domain
SN35N_1228	COG2274	protein secretion by the type I secretion system
SN35N_1233	COG3290	protein histidine kinase activity
SN35N_1240	COG1114	Component of the transport system for branched-chain amino acids
SN35N_1241	COG0561	phosphatase activity
SN35N_1243	COG0561	phosphatase activity
SN35N_1245	COG0110	maltose O-acetyltransferase activity
SN35N_1264	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_1266	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SN35N_1268	COG1125	glycine betaine transport
SN35N_1271	COG0300	oxidoreductase activity
SN35N_1277	COG1881	PFAM PEBP family protein
SN35N_1278	COG3759	membrane
SN35N_1280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SN35N_1284	COG0004	ammonium transporteR
SN35N_1288	COG1134	teichoic acid transport
SN35N_1289	COG1682	transport, permease protein
SN35N_1291	COG0436	Aminotransferase
SN35N_1294	COG1268	BioY protein
SN35N_1298	COG2801	Transposase and inactivated derivatives
SN35N_1304	COG1454	alcohol dehydrogenase
SN35N_1304	COG1012	belongs to the aldehyde dehydrogenase family
SN35N_1306	COG1131	(ABC) transporter
SN35N_1307	COG1725	Transcriptional regulator
SN35N_1313	COG3842	ATPase activity
SN35N_1318	COG1252	NADH dehydrogenase
SN35N_1319	COG1846	Transcriptional regulator
SN35N_1321	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SN35N_1327	COG1388	LysM domain
SN35N_1327	COG3942	CHAP domain
SN35N_1329	COG0741	lytic transglycosylase activity
SN35N_1332	COG1136	(ABC) transporter
SN35N_1333	COG0577	efflux transmembrane transporter activity
SN35N_1335	COG2818	Glycosylase
SN35N_1336	COG1033	growth of symbiont in host cell
SN35N_1336	COG2409	Drug exporters of the RND superfamily
SN35N_1338	COG2357	RelA SpoT domain protein
SN35N_1340	COG0277	FAD linked oxidase domain protein
SN35N_1341	COG1316	TRANSCRIPTIONal
SN35N_1344	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_1345	COG1737	Transcriptional regulator
SN35N_1347	COG0745	RESPONSE REGULATOR receiver
SN35N_1348	COG5002	protein histidine kinase activity
SN35N_1354	COG1914	H( )-stimulated, divalent metal cation uptake system
SN35N_1355	COG1309	transcriptional regulator
SN35N_1356	COG1959	2 iron, 2 sulfur cluster binding
SN35N_1358	COG0163	prenyltransferase activity
SN35N_1361	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SN35N_1362	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SN35N_1363	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SN35N_1365	COG1263	PTS System
SN35N_1365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1365	COG2190	(PTS) system
SN35N_1366	COG2190	(PTS) system
SN35N_1366	COG1263	PTS System
SN35N_1366	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1367	COG0366	Alpha amylase catalytic
SN35N_1368	COG2188	Transcriptional regulator
SN35N_1372	COG0024	Methionine aminopeptidase
SN35N_1374	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SN35N_1375	COG0626	cystathionine gamma-synthase activity
SN35N_1376	COG1045	serine acetyltransferase
SN35N_1380	COG3964	amidohydrolase
SN35N_1383	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_1384	COG2188	Transcriptional regulator
SN35N_1385	COG0431	NADPH-dependent FMN reductase
SN35N_1390	COG3118	belongs to the thioredoxin family
SN35N_1392	COG0246	Mannitol dehydrogenase
SN35N_1393	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1395	COG2213	PTS system mannitol-specific
SN35N_1398	COG3976	FMN-binding domain protein
SN35N_1398	COG1053	succinate dehydrogenase
SN35N_1400	COG0363	glucosamine-6-phosphate deaminase activity
SN35N_1403	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SN35N_1405	COG0386	Belongs to the glutathione peroxidase family
SN35N_1407	COG4172	Belongs to the ABC transporter superfamily
SN35N_1410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SN35N_1411	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SN35N_1417	COG0667	Aldo Keto reductase
SN35N_1418	COG0406	alpha-ribazole phosphatase activity
SN35N_1419	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SN35N_1420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SN35N_1422	COG4166	transmembrane transport
SN35N_1423	COG4166	transmembrane transport
SN35N_1427	COG2801	Transposase and inactivated derivatives
SN35N_1443	COG3842	ATPase activity
SN35N_1444	COG0366	Alpha amylase catalytic
SN35N_1446	COG3833	ABC-type maltose transport systems, permease component
SN35N_1447	COG1175	transmembrane transport
SN35N_1448	COG2182	Extracellular solute-binding protein
SN35N_1450	COG1609	Transcriptional regulator
SN35N_1451	COG1609	Transcriptional regulator
SN35N_1452	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_1453	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SN35N_1454	COG1461	Dihydroxyacetone kinase
SN35N_1455	COG2376	Dihydroxyacetone kinase
SN35N_1456	COG2376	Dihydroxyacetone kinase
SN35N_1457	COG1309	transcriptional regulator
SN35N_1458	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SN35N_1459	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SN35N_1462	COG1131	(ABC) transporter
SN35N_1463	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_1468	COG2188	Transcriptional regulator
SN35N_1470	COG4720	Psort location CytoplasmicMembrane, score
SN35N_1471	COG1122	ATPase activity
SN35N_1472	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SN35N_1478	COG0667	Aldo Keto reductase
SN35N_1479	COG0656	L-ascorbic acid biosynthetic process
SN35N_1480	COG2807	transmembrane transport
SN35N_1487	COG1983	PspC domain protein
SN35N_1489	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SN35N_1492	COG1518	maintenance of DNA repeat elements
SN35N_1493	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SN35N_1496	COG1113	amino acid transport
SN35N_1499	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SN35N_1501	COG0352	thiamine-phosphate diphosphorylase activity
SN35N_1502	COG0351	phosphomethylpyrimidine kinase
SN35N_1503	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SN35N_1504	COG0604	alcohol dehydrogenase
SN35N_1505	COG1606	tRNA processing
SN35N_1506	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_1507	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SN35N_1508	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SN35N_1509	COG1691	(AIR) carboxylase
SN35N_1510	COG3875	lactate racemase activity
SN35N_1511	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SN35N_1512	COG0310	cobalt ion transport
SN35N_1513	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SN35N_1514	COG1122	ATPase activity
SN35N_1518	COG4166	transmembrane transport
SN35N_1520	COG3022	response to hydroperoxide
SN35N_1521	COG2267	carboxylic ester hydrolase activity
SN35N_1525	COG0604	alcohol dehydrogenase
SN35N_1532	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SN35N_1536	COG2368	4-hydroxyphenylacetate
SN35N_1537	COG2365	Tyrosine phosphatase family
SN35N_1539	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SN35N_1540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SN35N_1541	COG2508	Transcriptional regulator
SN35N_1542	COG0778	Nitroreductase
SN35N_1544	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_1545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SN35N_1548	COG0471	metal ion transport
SN35N_1549	COG1053	succinate dehydrogenase
SN35N_1549	COG0431	NADPH-dependent FMN reductase
SN35N_1549	COG3976	FMN-binding domain protein
SN35N_1553	COG1573	uracil-dna glycosylase
SN35N_1554	COG1012	belongs to the aldehyde dehydrogenase family
SN35N_1557	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SN35N_1558	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SN35N_1559	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SN35N_1560	COG4853	Protein conserved in bacteria
SN35N_1562	COG5002	protein histidine kinase activity
SN35N_1563	COG0745	RESPONSE REGULATOR receiver
SN35N_1565	COG1278	Cold shock
SN35N_1567	COG1554	hydrolase, family 65, central catalytic
SN35N_1568	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SN35N_1570	COG3103	Sh3 type 3 domain protein
SN35N_1570	COG0366	Alpha amylase catalytic
SN35N_1571	COG0058	SHG alpha-glucan phosphorylase activity
SN35N_1572	COG0297	glycogen (starch) synthase activity
SN35N_1573	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SN35N_1574	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SN35N_1575	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SN35N_1576	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SN35N_1577	COG4166	transmembrane transport
SN35N_1578	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SN35N_1579	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SN35N_1580	COG2814	Major facilitator Superfamily
SN35N_1581	COG0305	Participates in initiation and elongation during chromosome replication
SN35N_1582	COG0359	binds to the 23S rRNA
SN35N_1584	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SN35N_1585	COG0629	single-stranded DNA binding
SN35N_1586	COG0360	Binds together with S18 to 16S ribosomal RNA
SN35N_1588	COG0187	DNA topoisomerase II activity
SN35N_1589	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SN35N_1590	COG2501	S4 domain
SN35N_1591	COG0592	DNA-directed DNA polymerase activity
SN35N_1592	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SN35N_1594	COG0594	ribonuclease P activity
SN35N_1595	COG0706	membrane insertase activity
SN35N_1596	COG1847	R3H domain protein
SN35N_1597	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SN35N_1598	COG0445	tRNA wobble uridine modification
SN35N_1603	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_1608	COG1307	EDD domain protein, DegV family
SN35N_1611	COG3479	Phenolic acid decarboxylase
SN35N_1612	COG1695	Transcriptional regulator
SN35N_1614	COG1454	alcohol dehydrogenase
SN35N_1614	COG1012	belongs to the aldehyde dehydrogenase family
SN35N_1615	COG1609	Transcriptional regulator
SN35N_1617	COG1869	D-ribose catabolic process
SN35N_1618	COG4975	Glucose uptake
SN35N_1622	COG3730	PTS system glucitol sorbitol-specific
SN35N_1623	COG3732	PTS system glucitol sorbitol-specific
SN35N_1625	COG0028	Belongs to the TPP enzyme family
SN35N_1626	COG1959	2 iron, 2 sulfur cluster binding
SN35N_1627	COG0028	Belongs to the TPP enzyme family
SN35N_1628	COG1304	FMN binding
SN35N_1631	COG3293	Transposase
SN35N_1633	COG4512	PFAM Accessory gene regulator B
SN35N_1637	COG1393	Belongs to the ArsC family
SN35N_1639	COG2261	transglycosylase associated protein
SN35N_1645	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SN35N_1646	COG1609	Transcriptional regulator
SN35N_1650	COG2160	L-arabinose isomerase activity
SN35N_1651	COG0110	maltose O-acetyltransferase activity
SN35N_1653	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SN35N_1654	COG1349	DNA-binding transcription factor activity
SN35N_1657	COG3414	Phosphotransferase system galactitol-specific IIB component
SN35N_1658	COG3775	system Galactitol-specific IIC component
SN35N_1661	COG3711	transcriptional antiterminator
SN35N_1665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SN35N_1668	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SN35N_1671	COG2211	Major facilitator Superfamily
SN35N_1675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1675	COG1263	PTS System
SN35N_1675	COG2190	(PTS) system
SN35N_1676	COG2723	6-phospho-beta-galactosidase activity
SN35N_1677	COG2723	6-phospho-beta-galactosidase activity
SN35N_1678	COG3711	transcriptional antiterminator
SN35N_1680	COG2723	6-phospho-beta-galactosidase activity
SN35N_1682	COG2971	BadF BadG BcrA BcrD
SN35N_1683	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SN35N_1684	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_1686	COG2267	carboxylic ester hydrolase activity
SN35N_1688	COG2271	Major facilitator Superfamily
SN35N_1691	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_1694	COG2271	Major facilitator Superfamily
SN35N_1695	COG0583	DNA-binding transcription factor activity
SN35N_1696	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SN35N_1697	COG0710	3-dehydroquinate dehydratase activity
SN35N_1702	COG0667	Aldo Keto reductase
SN35N_1703	COG1609	Transcriptional regulator
SN35N_1704	COG2017	converts alpha-aldose to the beta-anomer
SN35N_1705	COG2190	(PTS) system
SN35N_1705	COG2211	Major facilitator Superfamily
SN35N_1709	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SN35N_1710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SN35N_1711	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SN35N_1712	COG1609	Transcriptional regulator
SN35N_1713	COG2944	sequence-specific DNA binding
SN35N_1714	COG2184	nucleotidyltransferase activity
SN35N_1718	COG0477	Major facilitator Superfamily
SN35N_1723	COG1609	Transcriptional regulator
SN35N_1724	COG1874	Beta-galactosidase
SN35N_1726	COG1114	Component of the transport system for branched-chain amino acids
SN35N_1728	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_1738	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_1742	COG3590	peptidase
SN35N_1743	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SN35N_1747	COG1937	Protein conserved in bacteria
SN35N_1748	COG3118	belongs to the thioredoxin family
SN35N_1749	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SN35N_1750	COG2217	Heavy metal translocating P-type atpase
SN35N_1753	COG2226	methyltransferase
SN35N_1755	COG1309	transcriptional regulator
SN35N_1763	COG0076	glutamate decarboxylase activity
SN35N_1768	COG2207	Transcriptional regulator
SN35N_1777	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SN35N_1778	COG1968	undecaprenyl-diphosphatase activity
SN35N_1782	COG0656	L-ascorbic acid biosynthetic process
SN35N_1784	COG0737	Belongs to the 5'-nucleotidase family
SN35N_1794	COG0477	Major facilitator Superfamily
SN35N_1799	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SN35N_1802	COG0697	spore germination
SN35N_1807	COG0071	Belongs to the small heat shock protein (HSP20) family
SN35N_1810	COG1194	a g-specific adenine glycosylase
SN35N_1812	COG3189	MarR family transcriptional regulator
SN35N_1813	COG1393	Belongs to the ArsC family
SN35N_1816	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SN35N_1818	COG1113	amino acid transport
SN35N_1822	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SN35N_1823	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SN35N_1825	COG2315	Protein conserved in bacteria
SN35N_1827	COG2217	Heavy metal translocating P-type atpase
SN35N_1833	COG4989	oxidoreductase activity
SN35N_1834	COG2151	metal-sulfur cluster biosynthetic enzyme
SN35N_1835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SN35N_1836	COG1882	Formate acetyltransferase
SN35N_1837	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SN35N_1840	COG2814	Major facilitator Superfamily
SN35N_1841	COG0803	Belongs to the bacterial solute-binding protein 9 family
SN35N_1844	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SN35N_1845	COG0302	gtp cyclohydrolase
SN35N_1847	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SN35N_1854	COG0640	Transcriptional regulator
SN35N_1855	COG1272	protein, Hemolysin III
SN35N_1858	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SN35N_1859	COG0628	permease
SN35N_1860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SN35N_1861	COG3158	transport of potassium into the cell
SN35N_1862	COG0531	amino acid
SN35N_1864	COG1511	domain protein
SN35N_1867	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SN35N_1868	COG2365	Tyrosine phosphatase family
SN35N_1869	COG0516	GMP reductase activity
SN35N_1870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SN35N_1871	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SN35N_1874	COG1929	Belongs to the glycerate kinase type-1 family
SN35N_1876	COG1562	ergosterol biosynthetic process
SN35N_1877	COG1233	COG1233 Phytoene dehydrogenase and related
SN35N_1878	COG2738	Putative neutral zinc metallopeptidase
SN35N_1880	COG1307	EDD domain protein, DegV family
SN35N_1887	COG0735	belongs to the Fur family
SN35N_1894	COG2190	(PTS) system
SN35N_1894	COG1263	PTS System
SN35N_1894	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1898	COG3711	transcriptional antiterminator
SN35N_1898	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1899	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_1899	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1899	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_1900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_1901	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_1901	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_1901	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_1902	COG0383	alpha-mannosidase activity
SN35N_1904	COG0561	phosphatase activity
SN35N_1907	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SN35N_1908	COG4619	ABC transporter
SN35N_1909	COG0390	transport system, permease component
SN35N_1912	COG1609	Transcriptional regulator
SN35N_1914	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_1914	COG2190	(PTS) system
SN35N_1914	COG1263	PTS System
SN35N_1919	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SN35N_1920	COG1126	abc transporter atp-binding protein
SN35N_1921	COG0765	amino acid transport
SN35N_1922	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SN35N_1923	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SN35N_1924	COG0583	DNA-binding transcription factor activity
SN35N_1927	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SN35N_1928	COG0357	Ribosomal RNA small subunit methyltransferase G
SN35N_1930	COG1192	Involved in chromosome partitioning
SN35N_1931	COG1475	DNA binding
SN35N_1932	COG4481	Protein conserved in bacteria
SN35N_1933	COG0012	GTP binding
SN35N_1936	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SN35N_1937	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SN35N_1941	COG1686	Belongs to the peptidase S11 family
SN35N_1942	COG1247	-acetyltransferase
SN35N_1950	COG0515	serine threonine protein kinase
SN35N_1950	COG2815	serine threonine protein kinase
SN35N_1952	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SN35N_1954	COG1940	carbohydrate kinase activity
SN35N_1954	COG1846	Transcriptional regulator
SN35N_1955	COG0628	permease
SN35N_1956	COG0588	phosphoglycerate mutase activity
SN35N_1957	COG2226	methyltransferase
SN35N_1959	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SN35N_1961	COG1511	domain protein
SN35N_1963	COG0693	protein deglycase activity
SN35N_1966	COG2801	Transposase and inactivated derivatives
SN35N_1990	COG0588	phosphoglycerate mutase activity
SN35N_1995	COG0300	oxidoreductase activity
SN35N_1996	COG1733	regulation of RNA biosynthetic process
SN35N_2000	COG1012	belongs to the aldehyde dehydrogenase family
SN35N_2002	COG1309	transcriptional regulator
SN35N_2004	COG3279	Response regulator of the LytR AlgR family
SN35N_2005	COG3293	Transposase
SN35N_2007	COG0367	asparagine synthase
SN35N_2010	COG0367	asparagine synthase
SN35N_2014	COG2814	Major facilitator Superfamily
SN35N_2015	COG1733	regulation of RNA biosynthetic process
SN35N_2016	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SN35N_2024	COG1063	alcohol dehydrogenase
SN35N_2036	COG2217	Heavy metal translocating P-type atpase
SN35N_2041	COG0531	amino acid
SN35N_2045	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_2046	COG1473	amidohydrolase
SN35N_2048	COG1132	(ABC) transporter
SN35N_2049	COG1132	(ABC) transporter
SN35N_2053	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_2059	COG4221	oxidoreductase activity
SN35N_2063	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SN35N_2065	COG3706	GGDEF domain
SN35N_2068	COG0803	Belongs to the bacterial solute-binding protein 9 family
SN35N_2072	COG1388	LysM domain
SN35N_2072	COG0791	NLP P60 protein
SN35N_2073	COG0741	lytic transglycosylase activity
SN35N_2074	COG0789	Transcriptional regulator
SN35N_2076	COG2723	6-phospho-beta-galactosidase activity
SN35N_2077	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_2078	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_2087	COG0577	efflux transmembrane transporter activity
SN35N_2087	COG1136	(ABC) transporter
SN35N_2089	COG0640	Transcriptional regulator
SN35N_2093	COG1914	H( )-stimulated, divalent metal cation uptake system
SN35N_2095	COG2246	polysaccharide biosynthetic process
SN35N_2096	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SN35N_2096	COG5549	protein import
SN35N_2099	COG0559	Belongs to the binding-protein-dependent transport system permease family
SN35N_2102	COG0410	ABC transporter
SN35N_2109	COG4120	Belongs to the binding-protein-dependent transport system permease family
SN35N_2110	COG1116	anion transmembrane transporter activity
SN35N_2111	COG1263	PTS System
SN35N_2111	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_2111	COG2190	(PTS) system
SN35N_2112	COG0778	Nitroreductase
SN35N_2114	COG1132	(ABC) transporter
SN35N_2115	COG1940	carbohydrate kinase activity
SN35N_2120	COG0697	spore germination
SN35N_2129	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SN35N_2130	COG0471	metal ion transport
SN35N_2131	COG0583	DNA-binding transcription factor activity
SN35N_2135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SN35N_2137	COG0242	peptide deformylase activity
SN35N_2139	COG1328	CTP reductase activity
SN35N_2141	COG2200	EAL domain
SN35N_2149	COG2270	Major facilitator Superfamily
SN35N_2150	COG0531	amino acid
SN35N_2151	COG2267	carboxylic ester hydrolase activity
SN35N_2154	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SN35N_2155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SN35N_2157	COG0561	phosphatase activity
SN35N_2158	COG0488	(ABC) transporter
SN35N_2165	COG0640	Transcriptional regulator
SN35N_2167	COG1511	domain protein
SN35N_2167	COG1511	domain protein
SN35N_2169	COG2814	Major facilitator Superfamily
SN35N_2170	COG1132	(ABC) transporter
SN35N_2171	COG1132	(ABC) transporter
SN35N_2173	COG0667	Aldo Keto reductase
SN35N_2175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SN35N_2178	COG1011	Hydrolase
SN35N_2179	COG0110	maltose O-acetyltransferase activity
SN35N_2180	COG0589	response to stress
SN35N_2182	COG1396	sequence-specific DNA binding
SN35N_2187	COG3293	Transposase
SN35N_2189	COG0656	L-ascorbic acid biosynthetic process
SN35N_2190	COG0656	L-ascorbic acid biosynthetic process
SN35N_2191	COG4221	oxidoreductase activity
SN35N_2192	COG0789	Transcriptional regulator
SN35N_2195	COG0583	DNA-binding transcription factor activity
SN35N_2196	COG0656	L-ascorbic acid biosynthetic process
SN35N_2198	COG4975	Glucose uptake
SN35N_2202	COG0656	L-ascorbic acid biosynthetic process
SN35N_2203	COG1028	Short-chain dehydrogenase reductase Sdr
SN35N_2204	COG1063	alcohol dehydrogenase
SN35N_2206	COG2801	Transposase and inactivated derivatives
SN35N_2208	COG0583	DNA-binding transcription factor activity
SN35N_2213	COG0456	acetyltransferase
SN35N_2218	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SN35N_2223	COG0789	Transcriptional regulator
SN35N_2226	COG4221	oxidoreductase activity
SN35N_2228	COG4152	abc transporter atp-binding protein
SN35N_2230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SN35N_2233	COG0438	transferase activity, transferring glycosyl groups
SN35N_2235	COG0583	DNA-binding transcription factor activity
SN35N_2236	COG2855	membrane
SN35N_2237	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SN35N_2239	COG2814	Major facilitator Superfamily
SN35N_2241	COG2814	Major facilitator Superfamily
SN35N_2250	COG1136	(ABC) transporter
SN35N_2251	COG0577	efflux transmembrane transporter activity
SN35N_2254	COG0789	Transcriptional regulator
SN35N_2254	COG4978	Transcriptional regulator
SN35N_2255	COG4978	Transcriptional regulator
SN35N_2255	COG0789	Transcriptional regulator
SN35N_2256	COG1811	Na channel or pump
SN35N_2259	COG4990	cell redox homeostasis
SN35N_2262	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SN35N_2263	COG4720	Psort location CytoplasmicMembrane, score
SN35N_2268	COG3328	transposase activity
SN35N_2272	COG0531	amino acid
SN35N_2273	COG0710	3-dehydroquinate dehydratase activity
SN35N_2279	COG0716	FMN binding
SN35N_2284	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SN35N_2285	COG0561	phosphatase activity
SN35N_2288	COG1216	Glycosyl transferase, family 2
SN35N_2289	COG2188	Transcriptional regulator
SN35N_2290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SN35N_2291	COG1447	Phosphotransferase system cellobiose-specific component IIA
SN35N_2292	COG2723	6-phospho-beta-galactosidase activity
SN35N_2293	COG2723	6-phospho-beta-galactosidase activity
SN35N_2294	COG3048	D-serine ammonia-lyase activity
SN35N_2295	COG1131	(ABC) transporter
SN35N_2297	COG1309	transcriptional regulator
SN35N_2298	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SN35N_2299	COG1827	regulation of RNA biosynthetic process
SN35N_2306	COG1051	belongs to the nudix hydrolase family
SN35N_2307	COG0110	maltose O-acetyltransferase activity
SN35N_2309	COG0561	phosphatase activity
SN35N_2315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SN35N_2319	COG2246	polysaccharide biosynthetic process
SN35N_2321	COG0589	response to stress
SN35N_2323	COG1131	(ABC) transporter
SN35N_2324	COG1725	Transcriptional regulator
SN35N_2327	COG1136	(ABC) transporter
SN35N_2331	COG2365	Tyrosine phosphatase family
SN35N_2332	COG0095	Lipoate-protein ligase
SN35N_2333	COG1053	succinate dehydrogenase
SN35N_2333	COG3976	FMN-binding domain protein
SN35N_2333	COG0431	NADPH-dependent FMN reductase
SN35N_2334	COG3976	FMN-binding domain protein
SN35N_2334	COG1053	succinate dehydrogenase
SN35N_2334	COG0431	NADPH-dependent FMN reductase
SN35N_2336	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SN35N_2337	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SN35N_2338	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SN35N_2339	COG0047	phosphoribosylformylglycinamidine synthase activity
SN35N_2340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SN35N_2342	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SN35N_2343	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SN35N_2344	COG0138	bifunctional purine biosynthesis protein purh
SN35N_2345	COG0151	Belongs to the GarS family
SN35N_2347	COG1215	transferase activity, transferring glycosyl groups
SN35N_2352	COG2252	PERMEase
SN35N_2353	COG2233	PERMEase
SN35N_2354	COG2508	Transcriptional regulator
SN35N_2355	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SN35N_2356	COG0540	Belongs to the ATCase OTCase family
SN35N_2357	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SN35N_2358	COG0505	Belongs to the CarA family
SN35N_2359	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SN35N_2360	COG0167	dihydroorotate dehydrogenase activity
SN35N_2361	COG0284	orotidine-5'-phosphate decarboxylase activity
SN35N_2362	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SN35N_2364	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SN35N_2365	COG1074	ATP-dependent DNA helicase activity
SN35N_2367	COG0702	epimerase
SN35N_2368	COG0583	DNA-binding transcription factor activity
SN35N_2370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SN35N_2371	COG0436	Aminotransferase
SN35N_2372	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SN35N_2373	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SN35N_2375	COG0604	alcohol dehydrogenase
SN35N_2376	COG0789	Transcriptional regulator
SN35N_2377	COG2814	Major facilitator Superfamily
SN35N_2378	COG0025	NhaP-type Na H and K H
SN35N_2379	COG1780	Probably involved in ribonucleotide reductase function
SN35N_2381	COG1253	flavin adenine dinucleotide binding
SN35N_2387	COG1418	mRNA catabolic process
SN35N_2389	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SN35N_2390	COG2188	Transcriptional regulator
SN35N_2392	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SN35N_2395	COG1396	sequence-specific DNA binding
SN35N_2396	COG4640	response to antibiotic
SN35N_2399	COG0564	pseudouridine synthase activity
SN35N_2400	COG0589	response to stress
SN35N_2401	COG1705	Flagellar rod assembly protein muramidase FlgJ
SN35N_2402	COG0095	Lipoate-protein ligase
SN35N_2408	COG0626	cystathionine gamma-synthase activity
SN35N_2409	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SN35N_2410	COG1073	alpha beta
SN35N_2412	COG0028	Belongs to the TPP enzyme family
SN35N_2423	COG1725	Transcriptional regulator
SN35N_2424	COG1131	(ABC) transporter
SN35N_2426	COG1335	isochorismatase
SN35N_2428	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SN35N_2429	COG0025	NhaP-type Na H and K H
SN35N_2430	COG0673	inositol 2-dehydrogenase activity
SN35N_2431	COG0673	inositol 2-dehydrogenase activity
SN35N_2433	COG1609	Transcriptional regulator
SN35N_2435	COG0328	RNA-DNA hybrid ribonuclease activity
SN35N_2437	COG0778	Nitroreductase
SN35N_2438	COG2326	polyphosphate kinase activity
SN35N_2442	COG0492	ferredoxin-NADP+ reductase activity
SN35N_2443	COG0584	glycerophosphoryl diester phosphodiesterase
SN35N_2445	COG1368	sulfuric ester hydrolase activity
SN35N_2449	COG3548	integral membrane protein
SN35N_2452	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SN35N_2454	COG0300	oxidoreductase activity
SN35N_2455	COG0789	Transcriptional regulator
SN35N_2459	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SN35N_2460	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SN35N_2461	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SN35N_2462	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SN35N_2463	COG0131	Imidazoleglycerol-phosphate dehydratase
SN35N_2464	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SN35N_2465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SN35N_2466	COG0107	imidazoleglycerol-phosphate synthase activity
SN35N_2467	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SN35N_2468	COG0140	phosphoribosyl-ATP diphosphatase activity
SN35N_2469	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SN35N_2470	COG0110	maltose O-acetyltransferase activity
SN35N_2471	COG0861	Integral membrane protein TerC family
SN35N_2472	COG2084	Dehydrogenase
SN35N_2473	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_2475	COG4120	Belongs to the binding-protein-dependent transport system permease family
SN35N_2478	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SN35N_2481	COG1307	EDD domain protein, DegV family
SN35N_2482	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SN35N_2483	COG2190	(PTS) system
SN35N_2483	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_2483	COG1263	PTS System
SN35N_2484	COG3328	transposase activity
SN35N_2485	COG2190	(PTS) system
SN35N_2485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_2485	COG1263	PTS System
SN35N_2489	COG0488	(ABC) transporter
SN35N_2490	COG3706	GGDEF domain
SN35N_2493	COG1522	sequence-specific DNA binding
SN35N_2494	COG0791	NLP P60 protein
SN35N_2498	COG0477	Major facilitator Superfamily
SN35N_2502	COG3830	Belongs to the UPF0237 family
SN35N_2503	COG2848	UPF0210 protein
SN35N_2504	COG0745	RESPONSE REGULATOR receiver
SN35N_2505	COG3850	Histidine kinase
SN35N_2505	COG5002	protein histidine kinase activity
SN35N_2506	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SN35N_2507	COG4975	Glucose uptake
SN35N_2508	COG0166	Belongs to the GPI family
SN35N_2510	COG0577	efflux transmembrane transporter activity
SN35N_2510	COG1136	(ABC) transporter
SN35N_2512	COG1132	(ABC) transporter
SN35N_2522	COG4886	Leucine-rich repeat (LRR) protein
SN35N_2522	COG4932	domain protein
SN35N_2527	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SN35N_2540	COG4695	Portal protein
SN35N_2553	COG1396	sequence-specific DNA binding
SN35N_2607	COG0726	polysaccharide deacetylase
SN35N_2610	COG1132	(ABC) transporter
SN35N_2613	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SN35N_2615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SN35N_2616	COG1482	cell wall glycoprotein biosynthetic process
SN35N_2617	COG3442	glutamine amidotransferase
SN35N_2618	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SN35N_2619	COG1435	thymidine kinase activity
SN35N_2620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SN35N_2621	COG2890	protein-(glutamine-N5) methyltransferase activity
SN35N_2622	COG0009	L-threonylcarbamoyladenylate synthase
SN35N_2623	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SN35N_2624	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SN35N_2626	COG2233	PERMEase
SN35N_2627	COG0356	it plays a direct role in the translocation of protons across the membrane
SN35N_2628	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SN35N_2629	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SN35N_2630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SN35N_2631	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SN35N_2632	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SN35N_2633	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SN35N_2634	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SN35N_2635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SN35N_2637	COG1077	Cell shape determining protein MreB Mrl
SN35N_2638	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SN35N_2640	COG0772	Belongs to the SEDS family
SN35N_2641	COG0509	glycine decarboxylation via glycine cleavage system
SN35N_2642	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SN35N_2643	COG2011	ABC-type metal ion transport system permease component
SN35N_2644	COG1464	Belongs to the NlpA lipoprotein family
SN35N_2648	COG1181	Belongs to the D-alanine--D-alanine ligase family
SN35N_2652	COG0589	response to stress
SN35N_2654	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SN35N_2655	COG2918	glutathione biosynthetic process
SN35N_2655	COG0189	ligase activity
SN35N_2656	COG1609	Transcriptional regulator
SN35N_2657	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SN35N_2658	COG3715	PTS system
SN35N_2659	COG3716	PTS system mannose fructose sorbose family IID component
SN35N_2662	COG0640	Transcriptional regulator
SN35N_2665	COG4493	Belongs to the UPF0637 family
SN35N_2666	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SN35N_2667	COG1956	GAF domain-containing protein
SN35N_2668	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SN35N_2670	COG1104	cysteine desulfurase activity
SN35N_2671	COG0301	tRNA thio-modification
SN35N_2672	COG1181	Belongs to the D-alanine--D-alanine ligase family
SN35N_2672	COG2918	glutathione biosynthetic process
SN35N_2674	COG0525	valine-tRNA ligase activity
SN35N_2675	COG0285	dihydrofolate synthase activity
SN35N_2676	COG2003	Belongs to the UPF0758 family
SN35N_2677	COG1077	Cell shape determining protein MreB Mrl
SN35N_2678	COG1792	Involved in formation and maintenance of cell shape
SN35N_2680	COG0850	regulation of cytokinetic process
SN35N_2681	COG2894	cell division
SN35N_2682	COG0765	amino acid transport
SN35N_2683	COG1126	abc transporter atp-binding protein
SN35N_2684	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SN35N_2686	COG0527	aspartate kinase activity
SN35N_2687	COG0612	Peptidase, M16
SN35N_2688	COG0612	Peptidase, M16
SN35N_2689	COG1426	Protein conserved in bacteria
SN35N_2690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SN35N_2691	COG1546	Belongs to the CinA family
SN35N_2691	COG1058	Belongs to the CinA family
SN35N_2692	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SN35N_2693	COG1418	mRNA catabolic process
SN35N_2694	COG1692	metallophosphoesterase
SN35N_2695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SN35N_2696	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SN35N_2700	COG0632	four-way junction helicase activity
SN35N_2701	COG2255	four-way junction helicase activity
SN35N_2702	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SN35N_2703	COG0343	queuine tRNA-ribosyltransferase activity
SN35N_2704	COG1862	Preprotein translocase
SN35N_2705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SN35N_2706	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SN35N_2707	COG0513	Belongs to the DEAD box helicase family
SN35N_2708	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SN35N_2709	COG4472	Bacterial protein of unknown function (DUF965)
SN35N_2710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SN35N_2711	COG3906	Belongs to the UPF0473 family
SN35N_2713	COG1193	negative regulation of DNA recombination
SN35N_2714	COG3118	belongs to the thioredoxin family
SN35N_2715	COG1719	4-vinyl reductase, 4VR
SN35N_2716	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SN35N_2717	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SN35N_2719	COG0517	IMP dehydrogenase activity
SN35N_2720	COG2171	N-acyltransferase activity
SN35N_2721	COG1473	amidohydrolase
SN35N_2722	COG0668	transmembrane transport
SN35N_2725	COG0789	Transcriptional regulator
SN35N_2726	COG0006	proline dipeptidase activity
SN35N_2727	COG1609	Transcriptional regulator
SN35N_2730	COG0217	transcriptional regulatory protein
SN35N_2732	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SN35N_2738	COG0827	DNA restriction-modification system
SN35N_2739	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SN35N_2741	COG1113	amino acid transport
SN35N_2743	COG0737	Belongs to the 5'-nucleotidase family
SN35N_2744	COG4470	Protein conserved in bacteria
SN35N_2745	COG0647	UMP catabolic process
SN35N_2747	COG0586	Pfam SNARE associated Golgi protein
SN35N_2749	COG1098	S1 RNA binding domain
SN35N_2752	COG1234	tRNA 3'-trailer cleavage
SN35N_2753	COG1393	Belongs to the ArsC family
SN35N_2754	COG4862	establishment of competence for transformation
SN35N_2756	COG1164	Oligoendopeptidase f
SN35N_2758	COG2357	RelA SpoT domain protein
SN35N_2759	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SN35N_2760	COG0564	pseudouridine synthase activity
SN35N_2761	COG3142	Participates in the control of copper homeostasis
SN35N_2762	COG2706	6-phosphogluconolactonase activity
SN35N_2764	COG0628	permease
SN35N_2765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SN35N_2767	COG1114	Component of the transport system for branched-chain amino acids
SN35N_2769	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SN35N_2770	COG1674	ftsk spoiiie
SN35N_2773	COG2001	Belongs to the MraZ family
SN35N_2774	COG0275	rRNA processing
SN35N_2777	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SN35N_2778	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SN35N_2779	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SN35N_2780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SN35N_2783	COG1799	cell septum assembly
SN35N_2784	COG0762	integral membrane protein
SN35N_2786	COG3599	regulation of cell shape
SN35N_2787	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SN35N_2790	COG3279	Response regulator of the LytR AlgR family
SN35N_2792	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SN35N_2793	COG0494	nUDIX hydrolase
SN35N_2795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SN35N_2796	COG1104	cysteine desulfurase activity
SN35N_2798	COG0482	sulfurtransferase activity
SN35N_2799	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SN35N_2800	COG0569	domain protein
SN35N_2806	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SN35N_2807	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SN35N_2808	COG1388	LysM domain
SN35N_2808	COG3584	3D domain protein
SN35N_2810	COG1597	lipid kinase activity
SN35N_2811	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SN35N_2814	COG0242	peptide deformylase activity
SN35N_2819	COG0039	L-malate dehydrogenase activity
SN35N_2820	COG4476	Belongs to the UPF0223 family
SN35N_2821	COG0483	inositol monophosphate 1-phosphatase activity
SN35N_2826	COG0772	Belongs to the SEDS family
SN35N_2827	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SN35N_2828	COG4471	UPF0298 protein
SN35N_2829	COG0742	ribosomal rna small subunit methyltransferase
SN35N_2830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SN35N_2831	COG3480	Lon protease (S16) C-terminal proteolytic domain
SN35N_2832	COG1596	polysaccharide export
SN35N_2832	COG1555	photosystem II stabilization
SN35N_2833	COG2131	deaminase
SN35N_2834	COG2333	competence protein COMEC
SN35N_2834	COG0658	competence protein
SN35N_2835	COG1466	dna polymerase III delta subunit
SN35N_2836	COG0268	Binds directly to 16S ribosomal RNA
SN35N_2837	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SN35N_2838	COG2814	Major facilitator Superfamily
SN35N_2843	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SN35N_2844	COG0544	peptidyl-prolyl cis-trans isomerase activity
SN35N_2845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SN35N_2846	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SN35N_2850	COG0765	amino acid transport
SN35N_2851	COG1126	abc transporter atp-binding protein
SN35N_2852	COG0322	excinuclease ABC activity
SN35N_2854	COG0489	protein tyrosine kinase activity
SN35N_2856	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SN35N_2857	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SN35N_2858	COG0438	transferase activity, transferring glycosyl groups
SN35N_2863	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SN35N_2864	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_2864	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SN35N_2864	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SN35N_2865	COG1105	Belongs to the carbohydrate kinase PfkB family
SN35N_2866	COG1349	DNA-binding transcription factor activity
SN35N_2867	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SN35N_2869	COG1234	tRNA 3'-trailer cleavage
SN35N_2870	COG0300	oxidoreductase activity
SN35N_2871	COG5416	Lipopolysaccharide assembly protein A domain
SN35N_2872	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SN35N_2872	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SN35N_2873	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SN35N_2876	COG0393	Putative heavy-metal-binding
SN35N_2882	COG2176	DNA-directed DNA polymerase activity
SN35N_2936	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_2937	COG0772	Belongs to the SEDS family
SN35N_2940	COG1116	anion transmembrane transporter activity
SN35N_2941	COG1316	TRANSCRIPTIONal
SN35N_2943	COG0463	Glycosyl transferase, family 2
SN35N_2946	COG3425	synthase
SN35N_2948	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SN35N_2950	COG4224	UPF0291 protein
SN35N_2951	COG3763	UPF0154 protein
SN35N_2952	COG0204	Acyl-transferase
SN35N_2953	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SN35N_2954	COG2827	Endonuclease containing a URI domain
SN35N_2955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SN35N_2958	COG0052	Belongs to the universal ribosomal protein uS2 family
SN35N_2959	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SN35N_2960	COG0528	UMP kinase activity
SN35N_2961	COG0233	cytoplasmic translational termination
SN35N_2962	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SN35N_2963	COG4589	Belongs to the CDS family
SN35N_2964	COG0750	zinc metalloprotease
SN35N_2965	COG0442	prolyl-tRNA aminoacylation
SN35N_2966	COG2176	DNA-directed DNA polymerase activity
SN35N_2967	COG0779	Required for maturation of 30S ribosomal subunits
SN35N_2968	COG0195	Participates in both transcription termination and antitermination
SN35N_2969	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SN35N_2971	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SN35N_2972	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SN35N_2973	COG0738	Major facilitator superfamily
SN35N_2974	COG0738	Major facilitator superfamily
SN35N_2975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SN35N_2977	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SN35N_2978	COG0287	Prephenate dehydrogenase
SN35N_2979	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SN35N_2980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SN35N_2981	COG0196	riboflavin kinase activity
SN35N_2982	COG3527	Alpha-acetolactate decarboxylase
SN35N_2983	COG1420	regulation of RNA biosynthetic process
SN35N_2984	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SN35N_2985	COG0443	Heat shock 70 kDa protein
SN35N_2986	COG0484	heat shock protein binding
SN35N_2987	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SN35N_2989	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SN35N_2990	COG1696	Membrane protein involved in D-alanine export
SN35N_2991	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SN35N_2992	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SN35N_2993	COG0481	GTPase activity
SN35N_2996	COG2094	Belongs to the DNA glycosylase MPG family
SN35N_2997	COG2264	protein methyltransferase activity
SN35N_2998	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SN35N_3000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SN35N_3001	COG1490	D-aminoacyl-tRNA deacylase activity
SN35N_3002	COG0546	phosphoglycolate phosphatase activity
SN35N_3004	COG4991	sh3 domain protein
SN35N_3004	COG3103	Sh3 type 3 domain protein
SN35N_3004	COG0860	N-Acetylmuramoyl-L-alanine amidase
SN35N_3005	COG0124	histidyl-tRNA synthetase
SN35N_3006	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SN35N_3008	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SN35N_3010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SN35N_3012	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SN35N_3013	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SN35N_3014	COG1610	YqeY-like protein
SN35N_3015	COG1702	phosphate starvation-inducible protein PhoH
SN35N_3016	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SN35N_3017	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SN35N_3018	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SN35N_3019	COG1381	Involved in DNA repair and RecF pathway recombination
SN35N_3020	COG0752	glycyl-tRNA synthetase alpha subunit
SN35N_3021	COG0751	glycine-tRNA ligase activity
SN35N_3022	COG0358	DNA primase activity
SN35N_3023	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SN35N_3024	COG1725	Transcriptional regulator
SN35N_3025	COG1131	(ABC) transporter
SN35N_3029	COG1131	(ABC) transporter
SN35N_3034	COG0519	Catalyzes the synthesis of GMP from XMP
SN35N_3036	COG1131	(ABC) transporter
SN35N_3038	COG4585	Histidine kinase
SN35N_3039	COG2197	response regulator
SN35N_3040	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_3042	COG0604	alcohol dehydrogenase
SN35N_3043	COG0583	DNA-binding transcription factor activity
SN35N_3049	COG0546	phosphoglycolate phosphatase activity
SN35N_3054	COG2801	Transposase and inactivated derivatives
SN35N_3066	COG1393	Belongs to the ArsC family
SN35N_3068	COG1349	DNA-binding transcription factor activity
SN35N_3069	COG0446	pyridine nucleotide-disulphide oxidoreductase
SN35N_3071	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SN35N_3073	COG0477	Major facilitator Superfamily
SN35N_3074	COG0148	phosphopyruvate hydratase activity
SN35N_3075	COG2217	Heavy metal translocating P-type atpase
SN35N_3080	COG1846	Transcriptional regulator
SN35N_3082	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SN35N_3082	COG0574	Belongs to the PEP-utilizing enzyme family
SN35N_3088	COG2384	SAM-dependent methyltransferase
SN35N_3089	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SN35N_3091	COG0542	response to heat
SN35N_3093	COG0587	DNA-directed DNA polymerase activity
SN35N_3094	COG0205	6-phosphofructokinase activity
SN35N_3097	COG2996	Protein conserved in bacteria
SN35N_3098	COG4974	Belongs to the 'phage' integrase family
SN35N_3100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SN35N_3101	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SN35N_3102	COG1187	pseudouridine synthase activity
SN35N_3103	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SN35N_3105	COG0514	ATP-dependent DNA helicase (RecQ)
SN35N_3107	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SN35N_3108	COG0539	negative regulation of cytoplasmic translation
SN35N_3109	COG1160	GTP binding
SN35N_3111	COG0457	Tetratricopeptide repeat
SN35N_3112	COG0561	phosphatase activity
SN35N_3113	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SN35N_3114	COG0617	tRNA 3'-terminal CCA addition
SN35N_3116	COG0488	(ABC) transporter
SN35N_3117	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SN35N_3118	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SN35N_3119	COG1307	EDD domain protein, DegV family
SN35N_3120	COG2755	lipolytic protein G-D-S-L family
SN35N_3121	COG4698	Protein conserved in bacteria
SN35N_3122	COG4479	Belongs to the UPF0346 family
SN35N_3123	COG0793	Belongs to the peptidase S41A family
SN35N_3123	COG3409	Peptidoglycan-binding domain 1 protein
SN35N_3124	COG2814	Major facilitator Superfamily
SN35N_3127	COG0583	DNA-binding transcription factor activity
SN35N_3128	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SN35N_3129	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SN35N_3130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SN35N_3131	COG0758	DNA mediated transformation
SN35N_3132	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SN35N_3133	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SN35N_3134	COG4974	Belongs to the 'phage' integrase family
SN35N_3135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SN35N_3136	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SN35N_3138	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SN35N_3139	COG0187	DNA topoisomerase II activity
SN35N_3141	COG0583	DNA-binding transcription factor activity
SN35N_3142	COG1227	inorganic diphosphatase activity
SN35N_3143	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SN35N_4006	COG3409	Peptidoglycan-binding domain 1 protein
SN35N_4016	COG0582	viral genome integration into host DNA
SN35N_5006	COG1192	Involved in chromosome partitioning
SN35N_5020	COG2801	Transposase and inactivated derivatives
SN35N_5023	COG2217	Heavy metal translocating P-type atpase
SN35N_5026	COG3158	transport of potassium into the cell
SN35N_6002	COG1442	glycosyl transferase family 8
SN35N_6002	COG1216	Glycosyl transferase, family 2
SN35N_6003	COG3328	transposase activity
SN35N_6006	COG3328	transposase activity
SN35N_6009	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_6011	COG0463	Glycosyl transferase, family 2
SN35N_6014	COG1215	transferase activity, transferring glycosyl groups
SN35N_6016	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SN35N_6018	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SN35N_6020	COG4464	protein tyrosine phosphatase activity
SN35N_6021	COG2801	Transposase and inactivated derivatives
SN35N_6023	COG4464	protein tyrosine phosphatase activity
SN35N_6024	COG0489	protein tyrosine kinase activity
SN35N_6026	COG0438	transferase activity, transferring glycosyl groups
SN35N_6028	COG3328	transposase activity
SN35N_6029	COG0551	DNA topoisomerase type I activity
SN35N_6029	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SN35N_6039	COG1192	Involved in chromosome partitioning
SN35N_6043	COG4876	unkown
SN35N_7006	COG1388	LysM domain
SN35N_7007	COG2826	transposase and inactivated derivatives, IS30 family
SN35N_7026	COG0551	DNA topoisomerase type I activity
SN35N_7026	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SN35N_7031	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SN35N_7037	COG3316	Transposase and inactivated derivatives
SN35N_7039	COG2801	Transposase and inactivated derivatives
SN35N_7042	COG2217	Heavy metal translocating P-type atpase
SN35N_7045	COG3158	transport of potassium into the cell
SN35N_7049	COG3293	Transposase
SN35N_7051	COG1418	mRNA catabolic process
SN35N_7053	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SN35N_7054	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SN35N_7055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SN35N_7059	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SN35N_7060	COG3293	Transposase
SN35N_7065	COG3293	Transposase