locus-tag	class	description
llmg_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
llmg_0002	COG0592	DNA-directed DNA polymerase activity
llmg_0003	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
llmg_0004	COG1074	ATP-dependent DNA helicase activity
llmg_0007	COG0012	GTP binding
llmg_0012	COG0193	aminoacyl-tRNA hydrolase activity
llmg_0013	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
llmg_0015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
llmg_0019	COG0037	tRNA processing
llmg_0021	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
llmg_0022	COG2213	PTS system mannitol-specific
llmg_0024	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
llmg_0025	COG0246	Mannitol dehydrogenase
llmg_0055	COG0582	viral genome integration into host DNA
llmg_0061	COG0454	-acetyltransferase
llmg_0063	COG0659	secondary active sulfate transmembrane transporter activity
llmg_0064	COG3328	transposase activity
llmg_0065	COG3153	acetyltransferase
llmg_0066	COG0436	Aminotransferase
llmg_0067	COG1381	Involved in DNA repair and RecF pathway recombination
llmg_0072	COG0508	dehydrogenase complex catalyzes the overall conversion of
llmg_0075	COG0095	Lipoate-protein ligase
llmg_0076	COG0584	glycerophosphoryl diester phosphodiesterase
llmg_0077	COG1418	mRNA catabolic process
llmg_0079	COG0180	Tryptophanyl-tRNA synthetase
llmg_0080	COG1764	response to oxidative stress
llmg_0083	COG0416	fatty acid biosynthetic process
llmg_0085	COG0488	(ABC) transporter
llmg_0087	COG4221	oxidoreductase activity
llmg_0089	COG1309	transcriptional regulator
llmg_0092	COG4221	oxidoreductase activity
llmg_0095	COG0400	carboxylic ester hydrolase activity
llmg_0096	COG0346	lactoylglutathione lyase activity
llmg_0097	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
llmg_0098	COG0267	Belongs to the bacterial ribosomal protein bL33 family
llmg_0099	COG0333	Belongs to the bacterial ribosomal protein bL32 family
llmg_0102	COG1475	DNA binding
llmg_0103	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
llmg_0104	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
llmg_0106	COG0488	(ABC) transporter
llmg_0110	COG2264	protein methyltransferase activity
llmg_0111	COG1385	rRNA (uridine-N3-)-methyltransferase activity
llmg_0112	COG0726	polysaccharide deacetylase
llmg_0114	COG0463	Glycosyl transferase, family 2
llmg_0115	COG1490	D-aminoacyl-tRNA deacylase activity
llmg_0117	COG1011	Hydrolase
llmg_0118	COG0531	amino acid
llmg_0119	COG0204	Acyl-transferase
llmg_0122	COG2801	Transposase and inactivated derivatives
llmg_0123	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
llmg_0124	COG0653	protein targeting
llmg_0125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
llmg_0132	COG2076	Multidrug Resistance protein
llmg_0133	COG2814	Major facilitator Superfamily
llmg_0134	COG0463	Glycosyl transferase, family 2
llmg_0138	COG0137	argininosuccinate synthase activity
llmg_0139	COG0165	Argininosuccinate lyase
llmg_0142	COG0594	ribonuclease P activity
llmg_0143	COG0706	membrane insertase activity
llmg_0145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
llmg_0146	COG4989	oxidoreductase activity
llmg_0149	COG1266	CAAX protease self-immunity
llmg_0151	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
llmg_0152	COG3906	Belongs to the UPF0473 family
llmg_0154	COG0300	oxidoreductase activity
llmg_0156	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
llmg_0157	COG1309	transcriptional regulator
llmg_0158	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
llmg_0161	COG1309	transcriptional regulator
llmg_0164	COG0343	queuine tRNA-ribosyltransferase activity
llmg_0167	COG1832	CoA-binding protein
llmg_0171	COG0436	Aminotransferase
llmg_0172	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
llmg_0174	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
llmg_0175	COG0154	amidase activity
llmg_0176	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
llmg_0181	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
llmg_0184	COG0346	lactoylglutathione lyase activity
llmg_0187	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
llmg_0190	COG2723	6-phospho-beta-galactosidase activity
llmg_0191	COG0756	dUTP diphosphatase activity
llmg_0192	COG0737	Belongs to the 5'-nucleotidase family
llmg_0193	COG4470	Protein conserved in bacteria
llmg_0194	COG0820	rRNA (adenine-C2-)-methyltransferase activity
llmg_0196	COG0142	geranyltranstransferase activity
llmg_0201	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
llmg_0202	COG1461	Dihydroxyacetone kinase
llmg_0204	COG0227	Belongs to the bacterial ribosomal protein bL28 family
llmg_0206	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
llmg_0209	COG1088	dTDP-glucose 4,6-dehydratase activity
llmg_0212	COG1215	transferase activity, transferring glycosyl groups
llmg_0216	COG1216	Glycosyl transferase, family 2
llmg_0216	COG1442	glycosyl transferase family 8
llmg_0221	COG1216	Glycosyl transferase, family 2
llmg_0221	COG1442	glycosyl transferase family 8
llmg_0223	COG0438	transferase activity, transferring glycosyl groups
llmg_0224	COG0562	UDP-galactopyranose mutase
llmg_0231	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
llmg_0233	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
llmg_0235	COG1534	Rna-binding protein
llmg_0237	COG1713	HD superfamily hydrolase involved in NAD metabolism
llmg_0239	COG0799	negative regulation of ribosome biogenesis
llmg_0240	COG2226	methyltransferase
llmg_0241	COG1323	Belongs to the UPF0348 family
llmg_0242	COG0217	transcriptional regulatory protein
llmg_0244	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
llmg_0248	COG1309	transcriptional regulator
llmg_0249	COG0477	Major facilitator Superfamily
llmg_0250	COG0789	Transcriptional regulator
llmg_0251	COG0828	Belongs to the bacterial ribosomal protein bS21 family
llmg_0252	COG0561	phosphatase activity
llmg_0253	COG0126	phosphoglycerate kinase activity
llmg_0255	COG2376	Dihydroxyacetone kinase
llmg_0257	COG1461	Dihydroxyacetone kinase
llmg_0258	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
llmg_0260	COG4690	dipeptidase activity
llmg_0263	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
llmg_0264	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
llmg_0265	COG2081	HI0933 family
llmg_0266	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
llmg_0269	COG1132	(ABC) transporter
llmg_0271	COG0673	inositol 2-dehydrogenase activity
llmg_0273	COG1854	S-ribosylhomocysteine lyase activity
llmg_0276	COG0656	L-ascorbic acid biosynthetic process
llmg_0277	COG1335	isochorismatase
llmg_0280	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_0280	COG1388	LysM domain
llmg_0281	COG1328	CTP reductase activity
llmg_0287	COG1122	ATPase activity
llmg_0288	COG1122	ATPase activity
llmg_0289	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
llmg_0291	COG2171	N-acyltransferase activity
llmg_0292	COG1473	amidohydrolase
llmg_0293	COG0726	polysaccharide deacetylase
llmg_0296	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
llmg_0297	COG2183	response to ionizing radiation
llmg_0298	COG3091	SprT-like family
llmg_0299	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
llmg_0308	COG0456	acetyltransferase
llmg_0309	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
llmg_0315	COG3639	organic phosphonate transmembrane transporter activity
llmg_0316	COG0737	Belongs to the 5'-nucleotidase family
llmg_0318	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
llmg_0319	COG0308	aminopeptidase N
llmg_0321	COG1846	Transcriptional regulator
llmg_0322	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
llmg_0324	COG1132	(ABC) transporter
llmg_0325	COG1132	(ABC) transporter
llmg_0326	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
llmg_0327	COG4443	Transcriptional Coactivator p15 (PC4)
llmg_0332	COG1268	BioY protein
llmg_0333	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
llmg_0334	COG3859	Proton-coupled thiamine transporter YuaJ
llmg_0335	COG1464	Belongs to the NlpA lipoprotein family
llmg_0338	COG1464	Belongs to the NlpA lipoprotein family
llmg_0340	COG1464	Belongs to the NlpA lipoprotein family
llmg_0341	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
llmg_0342	COG2011	ABC-type metal ion transport system permease component
llmg_0344	COG1122	ATPase activity
llmg_0346	COG1120	ATPase activity
llmg_0347	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
llmg_0348	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
llmg_0349	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
llmg_0351	COG2814	Major facilitator Superfamily
llmg_0352	COG0656	L-ascorbic acid biosynthetic process
llmg_0353	COG1733	regulation of RNA biosynthetic process
llmg_0354	COG0346	lactoylglutathione lyase activity
llmg_0355	COG0588	phosphoglycerate mutase activity
llmg_0356	COG0450	alkyl hydroperoxide reductase
llmg_0357	COG3634	alkyl hydroperoxide reductase activity
llmg_0358	COG0768	penicillin binding
llmg_0359	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
llmg_0360	COG1181	Belongs to the D-alanine--D-alanine ligase family
llmg_0361	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
llmg_0362	COG4166	transmembrane transport
llmg_0364	COG0601	transmembrane transport
llmg_0365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
llmg_0366	COG0444	Belongs to the ABC transporter superfamily
llmg_0367	COG4608	Belongs to the ABC transporter superfamily
llmg_0368	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
llmg_0369	COG0513	Belongs to the DEAD box helicase family
llmg_0371	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
llmg_0372	COG0367	asparagine synthase
llmg_0375	COG1113	amino acid transport
llmg_0376	COG1113	amino acid transport
llmg_0382	COG2357	RelA SpoT domain protein
llmg_0383	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
llmg_0384	COG0564	pseudouridine synthase activity
llmg_0386	COG0833	amino acid
llmg_0389	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
llmg_0390	COG0583	DNA-binding transcription factor activity
llmg_0391	COG2855	membrane
llmg_0393	COG0583	DNA-binding transcription factor activity
llmg_0395	COG0301	tRNA thio-modification
llmg_0398	COG1764	response to oxidative stress
llmg_0399	COG0025	NhaP-type Na H and K H
llmg_0401	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
llmg_0402	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
llmg_0403	COG1363	Peptidase, m42
llmg_0406	COG3118	belongs to the thioredoxin family
llmg_0407	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
llmg_0408	COG0446	pyridine nucleotide-disulphide oxidoreductase
llmg_0410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
llmg_0411	COG0459	protein refolding
llmg_0412	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
llmg_0413	COG5002	protein histidine kinase activity
llmg_0414	COG0745	RESPONSE REGULATOR receiver
llmg_0415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
llmg_0416	COG0470	DNA polymerase III
llmg_0417	COG1774	PSP1 C-terminal conserved region
llmg_0418	COG4467	Involved in initiation control of chromosome replication
llmg_0424	COG1846	Transcriptional regulator
llmg_0425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
llmg_0428	COG1304	FMN binding
llmg_0429	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
llmg_0430	COG1966	Carbon starvation protein
llmg_0431	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
llmg_0432	COG2378	regulation of single-species biofilm formation
llmg_0433	COG0513	Belongs to the DEAD box helicase family
llmg_0435	COG1737	Transcriptional regulator
llmg_0437	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
llmg_0438	COG1447	Phosphotransferase system cellobiose-specific component IIA
llmg_0439	COG1737	Transcriptional regulator
llmg_0440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
llmg_0441	COG2723	6-phospho-beta-galactosidase activity
llmg_0444	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
llmg_0445	COG1597	lipid kinase activity
llmg_0446	COG3842	ATPase activity
llmg_0451	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
llmg_0452	COG2188	Transcriptional regulator
llmg_0453	COG2190	(PTS) system
llmg_0454	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
llmg_0454	COG1263	PTS System
llmg_0455	COG1554	hydrolase, family 65, central catalytic
llmg_0456	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
llmg_0459	COG0802	atpase or kinase
llmg_0461	COG1316	TRANSCRIPTIONal
llmg_0462	COG0101	tRNA pseudouridine synthase activity
llmg_0463	COG0351	phosphomethylpyrimidine kinase
llmg_0464	COG4720	Psort location CytoplasmicMembrane, score
llmg_0465	COG4475	Protein of unknown function (DUF436)
llmg_0466	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
llmg_0467	COG0504	CTP synthase activity
llmg_0479	COG1611	Belongs to the LOG family
llmg_0480	COG1428	Deoxynucleoside kinase
llmg_0483	COG0587	DNA-directed DNA polymerase activity
llmg_0484	COG1609	Transcriptional regulator
llmg_0487	COG1554	hydrolase, family 65, central catalytic
llmg_0490	COG0395	ABC-type sugar transport system, permease component
llmg_0491	COG1272	protein, Hemolysin III
llmg_0492	COG1307	EDD domain protein, DegV family
llmg_0493	COG2755	lipolytic protein G-D-S-L family
llmg_0494	COG1472	Belongs to the glycosyl hydrolase 3 family
llmg_0496	COG0776	regulation of translation
llmg_0497	COG0456	acetyltransferase
llmg_0498	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
llmg_0499	COG2169	Transcriptional regulator
llmg_0505	COG1104	cysteine desulfurase activity
llmg_0506	COG3883	PFAM NLP P60 protein
llmg_0506	COG0791	NLP P60 protein
llmg_0507	COG4166	transmembrane transport
llmg_0509	COG1388	LysM domain
llmg_0509	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_0512	COG3331	DNA recombination
llmg_0513	COG4474	Belongs to the UPF0398 family
llmg_0514	COG1393	Belongs to the ArsC family
llmg_0515	COG4476	Belongs to the UPF0223 family
llmg_0516	COG0483	inositol monophosphate 1-phosphatase activity
llmg_0517	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
llmg_0519	COG0544	peptidyl-prolyl cis-trans isomerase activity
llmg_0520	COG0358	DNA primase activity
llmg_0521	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
llmg_0528	COG0542	response to heat
llmg_0529	COG1959	2 iron, 2 sulfur cluster binding
llmg_0530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
llmg_0532	COG0242	peptide deformylase activity
llmg_0533	COG0494	nUDIX hydrolase
llmg_0534	COG0556	nucleotide-excision repair
llmg_0535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
llmg_0536	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
llmg_0538	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
llmg_0539	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
llmg_0540	COG0706	membrane insertase activity
llmg_0542	COG4684	Psort location CytoplasmicMembrane, score
llmg_0543	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
llmg_0546	COG1942	4-Oxalocrotonate Tautomerase
llmg_0547	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
llmg_0549	COG2801	Transposase and inactivated derivatives
llmg_0550	COG2963	transposase activity
llmg_0554	COG3328	transposase activity
llmg_0555	COG1435	thymidine kinase activity
llmg_0557	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
llmg_0559	COG0778	Nitroreductase
llmg_0560	COG2890	protein-(glutamine-N5) methyltransferase activity
llmg_0562	COG0009	L-threonylcarbamoyladenylate synthase
llmg_0563	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
llmg_0565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
llmg_0566	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
llmg_0567	COG0560	Phosphoserine phosphatase
llmg_0568	COG1254	Belongs to the acylphosphatase family
llmg_0570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
llmg_0572	COG0789	Transcriptional regulator
llmg_0574	COG0716	FMN binding
llmg_0577	COG0024	Methionine aminopeptidase
llmg_0579	COG2246	polysaccharide biosynthetic process
llmg_0582	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
llmg_0583	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
llmg_0585	COG4980	gas vesicle protein
llmg_0586	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
llmg_0588	COG3158	transport of potassium into the cell
llmg_0591	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
llmg_0594	COG0582	viral genome integration into host DNA
llmg_0600	COG0463	Glycosyl transferase, family 2
llmg_0604	COG1234	tRNA 3'-trailer cleavage
llmg_0605	COG0300	oxidoreductase activity
llmg_0606	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
llmg_0606	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
llmg_0607	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
llmg_0608	COG3343	RNA polymerase activity
llmg_0609	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
llmg_0610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
llmg_0613	COG2801	Transposase and inactivated derivatives
llmg_0615	COG0542	response to heat
llmg_0616	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
llmg_0617	COG0148	phosphopyruvate hydratase activity
llmg_0618	COG4974	Belongs to the 'phage' integrase family
llmg_0621	COG2801	Transposase and inactivated derivatives
llmg_0622	COG2963	transposase activity
llmg_0625	COG0577	efflux transmembrane transporter activity
llmg_0629	COG1882	Formate acetyltransferase
llmg_0630	COG0237	dephospho-CoA kinase activity
llmg_0631	COG2814	Major facilitator Superfamily
llmg_0632	COG0267	Belongs to the bacterial ribosomal protein bL33 family
llmg_0633	COG0772	Belongs to the SEDS family
llmg_0634	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
llmg_0635	COG0372	Belongs to the citrate synthase family
llmg_0636	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
llmg_0638	COG0740	serine-type endopeptidase activity
llmg_0640	COG1393	Belongs to the ArsC family
llmg_0643	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
llmg_0646	COG1215	transferase activity, transferring glycosyl groups
llmg_0647	COG2801	Transposase and inactivated derivatives
llmg_0648	COG2963	transposase activity
llmg_0650	COG1114	Component of the transport system for branched-chain amino acids
llmg_0652	COG2801	Transposase and inactivated derivatives
llmg_0663	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
llmg_0664	COG1473	amidohydrolase
llmg_0674	COG3316	Transposase and inactivated derivatives
llmg_0678	COG2963	transposase activity
llmg_0684	COG2801	Transposase and inactivated derivatives
llmg_0694	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
llmg_0697	COG0444	Belongs to the ABC transporter superfamily
llmg_0698	COG4608	Belongs to the ABC transporter superfamily
llmg_0699	COG0601	transmembrane transport
llmg_0700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
llmg_0702	COG3590	peptidase
llmg_0709	COG1695	Transcriptional regulator
llmg_0714	COG2801	Transposase and inactivated derivatives
llmg_0717	COG3316	Transposase and inactivated derivatives
llmg_0720	COG2963	transposase activity
llmg_0721	COG2801	Transposase and inactivated derivatives
llmg_0722	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
llmg_0727	COG3716	PTS system mannose fructose sorbose family IID component
llmg_0728	COG3715	PTS system
llmg_0732	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
llmg_0733	COG1316	TRANSCRIPTIONal
llmg_0737	COG3833	ABC-type maltose transport systems, permease component
llmg_0738	COG1175	transmembrane transport
llmg_0740	COG0366	Alpha amylase catalytic
llmg_0741	COG0366	Alpha amylase catalytic
llmg_0742	COG0110	maltose O-acetyltransferase activity
llmg_0743	COG0366	Alpha amylase catalytic
llmg_0746	COG1609	Transcriptional regulator
llmg_0747	COG0745	RESPONSE REGULATOR receiver
llmg_0748	COG5002	protein histidine kinase activity
llmg_0749	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
llmg_0750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
llmg_0751	COG2723	6-phospho-beta-galactosidase activity
llmg_0760	COG0741	lytic transglycosylase activity
llmg_0761	COG0673	inositol 2-dehydrogenase activity
llmg_0762	COG0572	uridine kinase
llmg_0763	COG0280	phosphate acetyltransferase
llmg_0765	COG0561	phosphatase activity
llmg_0766	COG1674	ftsk spoiiie
llmg_0768	COG1466	dna polymerase III delta subunit
llmg_0769	COG3599	regulation of cell shape
llmg_0771	COG0116	Belongs to the methyltransferase superfamily
llmg_0774	COG0006	proline dipeptidase activity
llmg_0775	COG1609	Transcriptional regulator
llmg_0776	COG0492	ferredoxin-NADP+ reductase activity
llmg_0777	COG1286	toxin biosynthetic process
llmg_0778	COG1193	negative regulation of DNA recombination
llmg_0779	COG3118	belongs to the thioredoxin family
llmg_0782	COG0710	3-dehydroquinate dehydratase activity
llmg_0783	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
llmg_0784	COG1609	Transcriptional regulator
llmg_0785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
llmg_0786	COG1869	D-ribose catabolic process
llmg_0788	COG1172	Belongs to the binding-protein-dependent transport system permease family
llmg_0789	COG1879	ABC-type sugar transport system periplasmic component
llmg_0790	COG0582	viral genome integration into host DNA
llmg_0797	COG3561	AntA/AntB antirepressor
llmg_0807	COG3935	DnaD domain protein
llmg_0808	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
llmg_0816	COG0756	dUTP diphosphatase activity
llmg_0824	COG5484	DNA packaging
llmg_0824	COG3728	DNA packaging
llmg_0830	COG2868	ribosomal protein
llmg_0851	COG3942	CHAP domain
llmg_0851	COG1388	LysM domain
llmg_0857	COG1802	Transcriptional regulator
llmg_0859	COG1312	Catalyzes the dehydration of D-mannonate
llmg_0862	COG1904	glucuronate isomerase
llmg_0864	COG0800	Aldolase
llmg_0865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
llmg_0871	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
llmg_0872	COG0494	nUDIX hydrolase
llmg_0874	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
llmg_0875	COG1285	pathogenesis
llmg_0878	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
llmg_0886	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
llmg_0887	COG1230	cation diffusion facilitator family transporter
llmg_0890	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
llmg_0893	COG0540	Belongs to the ATCase OTCase family
llmg_0894	COG0505	Belongs to the CarA family
llmg_0900	COG2963	transposase activity
llmg_0901	COG2801	Transposase and inactivated derivatives
llmg_0902	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
llmg_0903	COG1408	metallophosphoesterase
llmg_0904	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_0904	COG3942	CHAP domain
llmg_0906	COG0254	rRNA binding
llmg_0908	COG0745	RESPONSE REGULATOR receiver
llmg_0909	COG5002	protein histidine kinase activity
llmg_0910	COG0004	ammonium transporteR
llmg_0911	COG0347	Belongs to the P(II) protein family
llmg_0912	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
llmg_0913	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
llmg_0915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
llmg_0926	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
llmg_0928	COG0363	glucosamine-6-phosphate deaminase activity
llmg_0929	COG3425	synthase
llmg_0930	COG0183	Belongs to the thiolase family
llmg_0932	COG0228	four-way junction DNA binding
llmg_0933	COG1837	Belongs to the UPF0109 family
llmg_0936	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
llmg_0937	COG0336	Belongs to the RNA methyltransferase TrmD family
llmg_0939	COG1307	EDD domain protein, DegV family
llmg_0940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
llmg_0942	COG0617	tRNA 3'-terminal CCA addition
llmg_0943	COG4690	dipeptidase activity
llmg_0945	COG0371	Dehydrogenase
llmg_0948	COG0488	(ABC) transporter
llmg_0950	COG0673	inositol 2-dehydrogenase activity
llmg_0951	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
llmg_0955	COG1063	alcohol dehydrogenase
llmg_0957	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
llmg_0958	COG0698	ribose 5-phosphate isomerase
llmg_0959	COG2723	6-phospho-beta-galactosidase activity
llmg_0960	COG2723	6-phospho-beta-galactosidase activity
llmg_0961	COG1940	carbohydrate kinase activity
llmg_0963	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
llmg_0966	COG1846	Transcriptional regulator
llmg_0967	COG0477	Major facilitator Superfamily
llmg_0968	COG4221	oxidoreductase activity
llmg_0970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
llmg_0986	COG0542	response to heat
llmg_0987	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
llmg_0988	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
llmg_0994	COG0138	bifunctional purine biosynthesis protein purh
llmg_0995	COG1011	Hydrolase
llmg_0997	COG0151	Belongs to the GarS family
llmg_0998	COG0561	phosphatase activity
llmg_0999	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
llmg_1003	COG3316	Transposase and inactivated derivatives
llmg_1004	COG2723	6-phospho-beta-galactosidase activity
llmg_1008	COG0518	GMP synthase (glutamine-hydrolyzing) activity
llmg_1008	COG0519	Catalyzes the synthesis of GMP from XMP
llmg_1009	COG4209	transmembrane transport
llmg_1010	COG0395	ABC-type sugar transport system, permease component
llmg_1017	COG1846	Transcriptional regulator
llmg_1019	COG0300	oxidoreductase activity
llmg_1020	COG0789	Transcriptional regulator
llmg_1021	COG0697	spore germination
llmg_1023	COG0735	belongs to the Fur family
llmg_1028	COG0778	Nitroreductase
llmg_1029	COG3759	membrane
llmg_1030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
llmg_1031	COG0512	Glutamine amidotransferase of anthranilate synthase
llmg_1032	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
llmg_1038	COG0134	indole-3-glycerol-phosphate synthase activity
llmg_1039	COG0135	phosphoribosylanthranilate isomerase activity
llmg_1041	COG0133	tryptophan synthase activity
llmg_1042	COG0159	tryptophan synthase activity
llmg_1045	COG1263	PTS System
llmg_1045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
llmg_1045	COG2190	(PTS) system
llmg_1046	COG2723	6-phospho-beta-galactosidase activity
llmg_1048	COG4175	Glycine betaine
llmg_1048	COG3448	diguanylate cyclase activity
llmg_1052	COG3969	phosphoadenosine phosphosulfate
llmg_1054	COG1475	DNA binding
llmg_1057	COG3223	Belongs to the PsiE family
llmg_1058	COG1072	(Pantothenic acid kinase))
llmg_1059	COG2813	Specifically methylates the guanine in position
llmg_1062	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
llmg_1064	COG1744	ABC transporter substrate-binding protein PnrA-like
llmg_1068	COG0745	RESPONSE REGULATOR receiver
llmg_1069	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
llmg_1073	COG2801	Transposase and inactivated derivatives
llmg_1077	COG0346	lactoylglutathione lyase activity
llmg_1086	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
llmg_1087	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_1088	COG0386	Belongs to the glutathione peroxidase family
llmg_1089	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
llmg_1097	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
llmg_1098	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
llmg_1099	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
llmg_1100	COG1187	pseudouridine synthase activity
llmg_1104	COG0477	Major facilitator Superfamily
llmg_1105	COG0543	2 iron, 2 sulfur cluster binding
llmg_1106	COG0167	dihydroorotate dehydrogenase activity
llmg_1107	COG0284	orotidine-5'-phosphate decarboxylase activity
llmg_1109	COG0357	Ribosomal RNA small subunit methyltransferase G
llmg_1110	COG0142	geranyltranstransferase activity
llmg_1114	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
llmg_1116	COG3853	Toxic anion resistance protein (TelA)
llmg_1119	COG0469	pyruvate kinase activity
llmg_1120	COG0039	L-malate dehydrogenase activity
llmg_1124	COG2226	methyltransferase
llmg_1130	COG1393	Belongs to the ArsC family
llmg_1131	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
llmg_1132	COG0420	3'-5' exonuclease activity
llmg_1133	COG0419	ATPase involved in DNA repair
llmg_1138	COG0803	Belongs to the bacterial solute-binding protein 9 family
llmg_1141	COG1396	sequence-specific DNA binding
llmg_1142	COG3328	transposase activity
llmg_1144	COG2801	Transposase and inactivated derivatives
llmg_1145	COG2963	transposase activity
llmg_1149	COG2423	ornithine cyclodeaminase activity
llmg_1151	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
llmg_1155	COG1393	Belongs to the ArsC family
llmg_1165	COG0395	ABC-type sugar transport system, permease component
llmg_1172	COG1349	DNA-binding transcription factor activity
llmg_1176	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
llmg_1178	COG0531	amino acid
llmg_1179	COG0076	glutamate decarboxylase activity
llmg_1180	COG0668	transmembrane transport
llmg_1181	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
llmg_1182	COG0110	maltose O-acetyltransferase activity
llmg_1183	COG0070	glutamate synthase
llmg_1183	COG0069	glutamate synthase activity
llmg_1183	COG0067	glutamate synthase
llmg_1184	COG0493	'glutamate synthase
llmg_1186	COG3763	UPF0154 protein
llmg_1187	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
llmg_1188	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
llmg_1191	COG4974	Belongs to the 'phage' integrase family
llmg_1192	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
llmg_1193	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
llmg_1194	COG1187	pseudouridine synthase activity
llmg_1195	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
llmg_1202	COG1132	(ABC) transporter
llmg_1203	COG1132	(ABC) transporter
llmg_1204	COG3620	sequence-specific DNA binding
llmg_1207	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
llmg_1208	COG0222	ribosome binding
llmg_1209	COG1846	Transcriptional regulator
llmg_1210	COG2814	Major facilitator Superfamily
llmg_1216	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
llmg_1217	COG0351	phosphomethylpyrimidine kinase
llmg_1218	COG0352	thiamine-phosphate diphosphorylase activity
llmg_1219	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
llmg_1220	COG1696	Membrane protein involved in D-alanine export
llmg_1221	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
llmg_1222	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
llmg_1223	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
llmg_1225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
llmg_1227	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
llmg_1233	COG2801	Transposase and inactivated derivatives
llmg_1234	COG2963	transposase activity
llmg_1235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
llmg_1241	COG1940	carbohydrate kinase activity
llmg_1244	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
llmg_1245	COG0561	phosphatase activity
llmg_1249	COG0446	pyridine nucleotide-disulphide oxidoreductase
llmg_1250	COG0798	PFAM Bile acid sodium symporter
llmg_1253	COG0656	L-ascorbic acid biosynthetic process
llmg_1255	COG1278	Cold shock
llmg_1257	COG2261	transglycosylase associated protein
llmg_1264	COG2963	transposase activity
llmg_1265	COG2801	Transposase and inactivated derivatives
llmg_1268	COG4974	Belongs to the 'phage' integrase family
llmg_1270	COG4974	Belongs to the 'phage' integrase family
llmg_1271	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
llmg_1272	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
llmg_1273	COG0758	DNA mediated transformation
llmg_1274	COG0251	oxidation-reduction process
llmg_1275	COG3527	Alpha-acetolactate decarboxylase
llmg_1276	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
llmg_1277	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
llmg_1278	COG0440	acetolactate synthase activity
llmg_1279	COG0028	Belongs to the TPP enzyme family
llmg_1280	COG0129	dihydroxy-acid dehydratase activity
llmg_1281	COG1119	ATPase activity
llmg_1282	COG0066	3-isopropylmalate dehydratase activity
llmg_1284	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
llmg_1288	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
llmg_1289	COG0140	phosphoribosyl-ATP diphosphatase activity
llmg_1289	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
llmg_1290	COG0107	imidazoleglycerol-phosphate synthase activity
llmg_1291	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
llmg_1292	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
llmg_1293	COG3231	kanamycin kinase activity
llmg_1294	COG0131	Imidazoleglycerol-phosphate dehydratase
llmg_1295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
llmg_1296	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
llmg_1297	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
llmg_1298	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
llmg_1301	COG1461	Dihydroxyacetone kinase
llmg_1304	COG0557	exoribonuclease II activity
llmg_1309	COG0028	Belongs to the TPP enzyme family
llmg_1311	COG0628	permease
llmg_1313	COG2226	methyltransferase
llmg_1314	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
llmg_1315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
llmg_1317	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
llmg_1318	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
llmg_1319	COG3328	transposase activity
llmg_1320	COG3507	Belongs to the glycosyl hydrolase 43 family
llmg_1323	COG3328	transposase activity
llmg_1324	COG2207	Transcriptional regulator
llmg_1324	COG1917	Cupin 2, conserved barrel domain protein
llmg_1325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
llmg_1326	COG1177	transmembrane transport
llmg_1327	COG1176	ABC-type spermidine putrescine transport system, permease component I
llmg_1329	COG0812	UDP-N-acetylmuramate dehydrogenase activity
llmg_1333	COG1428	Deoxynucleoside kinase
llmg_1334	COG0285	dihydrofolate synthase activity
llmg_1335	COG1051	belongs to the nudix hydrolase family
llmg_1336	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
llmg_1337	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
llmg_1337	COG0302	gtp cyclohydrolase
llmg_1339	COG0218	Necessary for normal cell division and for the maintenance of normal septation
llmg_1340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
llmg_1342	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
llmg_1343	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
llmg_1345	COG2233	PERMEase
llmg_1346	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
llmg_1351	COG2310	stress, protein
llmg_1352	COG2310	stress, protein
llmg_1361	COG4974	Belongs to the 'phage' integrase family
llmg_1367	COG2801	Transposase and inactivated derivatives
llmg_1368	COG2963	transposase activity
llmg_1390	COG3942	CHAP domain
llmg_1390	COG1388	LysM domain
llmg_1400	COG0484	heat shock protein binding
llmg_1412	COG0516	GMP reductase activity
llmg_1414	COG0647	UMP catabolic process
llmg_1418	COG0635	Involved in the biosynthesis of porphyrin-containing compound
llmg_1419	COG1475	DNA binding
llmg_1420	COG3969	phosphoadenosine phosphosulfate
llmg_1424	COG0149	triose-phosphate isomerase activity
llmg_1425	COG1737	Transcriptional regulator
llmg_1426	COG1263	PTS System
llmg_1426	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
llmg_1427	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
llmg_1429	COG0039	L-malate dehydrogenase activity
llmg_1430	COG0196	riboflavin kinase activity
llmg_1431	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
llmg_1437	COG2801	Transposase and inactivated derivatives
llmg_1438	COG2963	transposase activity
llmg_1441	COG1053	succinate dehydrogenase
llmg_1445	COG0210	DNA helicase
llmg_1449	COG3764	Sortase (surface protein transpeptidase)
llmg_1452	COG0531	amino acid
llmg_1453	COG0702	epimerase
llmg_1454	COG1940	carbohydrate kinase activity
llmg_1455	COG2723	6-phospho-beta-galactosidase activity
llmg_1456	COG1472	Belongs to the glycosyl hydrolase 3 family
llmg_1457	COG0444	Belongs to the ABC transporter superfamily
llmg_1458	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
llmg_1459	COG0601	transmembrane transport
llmg_1460	COG4608	Belongs to the ABC transporter superfamily
llmg_1463	COG0481	GTPase activity
llmg_1464	COG3527	Alpha-acetolactate decarboxylase
llmg_1465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
llmg_1466	COG3442	glutamine amidotransferase
llmg_1468	COG1136	(ABC) transporter
llmg_1470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
llmg_1472	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
llmg_1473	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
llmg_1474	COG0038	chloride channel
llmg_1475	COG4224	UPF0291 protein
llmg_1477	COG0751	glycine-tRNA ligase activity
llmg_1479	COG0737	Belongs to the 5'-nucleotidase family
llmg_1482	COG1739	Uncharacterized protein family UPF0029
llmg_1483	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
llmg_1484	COG1040	competence protein
llmg_1486	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
llmg_1487	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
llmg_1489	COG1702	phosphate starvation-inducible protein PhoH
llmg_1491	COG0211	Belongs to the bacterial ribosomal protein bL27 family
llmg_1493	COG0261	This protein binds to 23S rRNA in the presence of protein L20
llmg_1496	COG1078	dGTPase activity
llmg_1499	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
llmg_1500	COG2384	SAM-dependent methyltransferase
llmg_1501	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
llmg_1508	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
llmg_1509	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
llmg_1512	COG0488	(ABC) transporter
llmg_1513	COG1393	Belongs to the ArsC family
llmg_1515	COG2003	Belongs to the UPF0758 family
llmg_1516	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
llmg_1517	COG0671	phosphoesterase, PA-phosphatase related
llmg_1518	COG5002	protein histidine kinase activity
llmg_1520	COG0745	RESPONSE REGULATOR receiver
llmg_1521	COG0463	Glycosyl transferase, family 2
llmg_1523	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
llmg_1524	COG0564	pseudouridine synthase activity
llmg_1525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
llmg_1529	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
llmg_1530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
llmg_1530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
llmg_1536	COG2153	protein acetylation
llmg_1537	COG2176	DNA-directed DNA polymerase activity
llmg_1539	COG0187	DNA topoisomerase II activity
llmg_1540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
llmg_1541	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
llmg_1542	COG1780	Probably involved in ribonucleotide reductase function
llmg_1543	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
llmg_1544	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
llmg_1545	COG2177	Part of the ABC transporter FtsEX involved in
llmg_1546	COG2884	Cell division ATP-binding protein ftsE
llmg_1547	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
llmg_1550	COG3557	Belongs to the UPF0374 family
llmg_1551	COG2116	formate transmembrane transporter activity
llmg_1553	COG1131	(ABC) transporter
llmg_1555	COG1481	regulation of sporulation
llmg_1556	COG0391	Required for morphogenesis under gluconeogenic growth conditions
llmg_1557	COG1660	Displays ATPase and GTPase activities
llmg_1558	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
llmg_1559	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
llmg_1565	COG2801	Transposase and inactivated derivatives
llmg_1568	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
llmg_1568	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
llmg_1568	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
llmg_1569	COG1105	Belongs to the carbohydrate kinase PfkB family
llmg_1570	COG1349	DNA-binding transcription factor activity
llmg_1573	COG5617	Psort location CytoplasmicMembrane, score
llmg_1574	COG0443	Heat shock 70 kDa protein
llmg_1575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
llmg_1576	COG1420	regulation of RNA biosynthetic process
llmg_1579	COG0588	phosphoglycerate mutase activity
llmg_1582	COG3830	Belongs to the UPF0237 family
llmg_1586	COG0557	exoribonuclease II activity
llmg_1588	COG0492	ferredoxin-NADP+ reductase activity
llmg_1590	COG1126	abc transporter atp-binding protein
llmg_1591	COG0765	amino acid transport
llmg_1593	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
llmg_1595	COG2759	Belongs to the formate--tetrahydrofolate ligase family
llmg_1599	COG0813	purine-nucleoside phosphorylase activity
llmg_1601	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
llmg_1602	COG1316	TRANSCRIPTIONal
llmg_1604	COG0463	Glycosyl transferase, family 2
llmg_1604	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
llmg_1606	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
llmg_1616	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
llmg_1617	COG1216	Glycosyl transferase, family 2
llmg_1622	COG1682	transport, permease protein
llmg_1623	COG1134	teichoic acid transport
llmg_1623	COG1388	LysM domain
llmg_1631	COG0187	DNA topoisomerase II activity
llmg_1633	COG2514	catechol 2,3-dioxygenase activity
llmg_1638	COG0281	malic enzyme
llmg_1639	COG0488	(ABC) transporter
llmg_1642	COG1063	alcohol dehydrogenase
llmg_1643	COG0772	Belongs to the SEDS family
llmg_1645	COG0539	negative regulation of cytoplasmic translation
llmg_1648	COG2197	response regulator
llmg_1649	COG4585	Histidine kinase
llmg_1654	COG2801	Transposase and inactivated derivatives
llmg_1655	COG2963	transposase activity
llmg_1657	COG4974	Belongs to the 'phage' integrase family
llmg_1658	COG2151	metal-sulfur cluster biosynthetic enzyme
llmg_1659	COG1511	domain protein
llmg_1661	COG0776	regulation of translation
llmg_1662	COG0589	response to stress
llmg_1667	COG1215	transferase activity, transferring glycosyl groups
llmg_1670	COG4319	ketosteroid isomerase
llmg_1671	COG0335	large ribosomal subunit rRNA binding
llmg_1672	COG2357	RelA SpoT domain protein
llmg_1674	COG0583	DNA-binding transcription factor activity
llmg_1675	COG1136	(ABC) transporter
llmg_1676	COG0577	efflux transmembrane transporter activity
llmg_1678	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
llmg_1679	COG0768	penicillin binding
llmg_1681	COG0275	rRNA processing
llmg_1685	COG0497	DNA recombination
llmg_1686	COG1438	arginine binding
llmg_1687	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
llmg_1691	COG1722	exodeoxyribonuclease VII activity
llmg_1692	COG1570	exodeoxyribonuclease VII activity
llmg_1693	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
llmg_1694	COG2217	Heavy metal translocating P-type atpase
llmg_1699	COG1174	glycine betaine transport
llmg_1704	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
llmg_1705	COG0736	holo-[acyl-carrier-protein] synthase activity
llmg_1709	COG0110	maltose O-acetyltransferase activity
llmg_1710	COG1442	glycosyl transferase family 8
llmg_1710	COG1216	Glycosyl transferase, family 2
llmg_1713	COG2801	Transposase and inactivated derivatives
llmg_1714	COG2963	transposase activity
llmg_1716	COG2801	Transposase and inactivated derivatives
llmg_1717	COG1194	a g-specific adenine glycosylase
llmg_1718	COG0322	excinuclease ABC activity
llmg_1719	COG3201	nicotinamide mononucleotide transporter
llmg_1724	COG0539	negative regulation of cytoplasmic translation
llmg_1725	COG0482	sulfurtransferase activity
llmg_1729	COG2217	Heavy metal translocating P-type atpase
llmg_1730	COG2608	mercury ion transmembrane transporter activity
llmg_1731	COG3682	Transcriptional regulator
llmg_1732	COG1760	l-serine dehydratase
llmg_1733	COG1760	l-serine dehydratase
llmg_1734	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
llmg_1735	COG1252	NADH dehydrogenase
llmg_1738	COG2723	6-phospho-beta-galactosidase activity
llmg_1741	COG0495	leucyl-tRNA aminoacylation
llmg_1743	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
llmg_1744	COG0552	protein localization to endoplasmic reticulum
llmg_1746	COG0561	phosphatase activity
llmg_1747	COG1113	amino acid transport
llmg_1751	COG1368	sulfuric ester hydrolase activity
llmg_1752	COG1196	nuclear chromosome segregation
llmg_1753	COG0571	ribonuclease III activity
llmg_1754	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
llmg_1755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
llmg_1756	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
llmg_1757	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
llmg_1758	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
llmg_1759	COG2910	NAD(P)H-binding
llmg_1760	COG4708	membrane
llmg_1762	COG1028	Short-chain dehydrogenase reductase Sdr
llmg_1764	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
llmg_1764	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
llmg_1765	COG0708	Exodeoxyribonuclease III
llmg_1767	COG1349	DNA-binding transcription factor activity
llmg_1768	COG1393	Belongs to the ArsC family
llmg_1770	COG0446	pyridine nucleotide-disulphide oxidoreductase
llmg_1771	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
llmg_1775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
llmg_1776	COG0626	cystathionine gamma-synthase activity
llmg_1778	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
llmg_1779	COG0439	Biotin carboxylase
llmg_1781	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
llmg_1783	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
llmg_1784	COG1028	Short-chain dehydrogenase reductase Sdr
llmg_1785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
llmg_1786	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
llmg_1787	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
llmg_1789	COG1482	cell wall glycoprotein biosynthetic process
llmg_1791	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
llmg_1792	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
llmg_1794	COG2740	Nucleic-acid-binding protein implicated in transcription termination
llmg_1796	COG0195	Participates in both transcription termination and antitermination
llmg_1797	COG0779	Required for maturation of 30S ribosomal subunits
llmg_1799	COG1346	cytolysis
llmg_1805	COG1160	GTP binding
llmg_1807	COG0778	Nitroreductase
llmg_1808	COG1484	DNA-dependent DNA replication
llmg_1810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
llmg_1811	COG0220	tRNA (guanine-N7-)-methyltransferase activity
llmg_1814	COG0305	Participates in initiation and elongation during chromosome replication
llmg_1815	COG0359	binds to the 23S rRNA
llmg_1817	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
llmg_1820	COG0527	aspartate kinase activity
llmg_1822	COG0561	phosphatase activity
llmg_1823	COG0252	asparaginase activity
llmg_1825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
llmg_1826	COG4109	DRTGG domain
llmg_1828	COG1169	isochorismate synthase
llmg_1829	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
llmg_1830	COG2267	carboxylic ester hydrolase activity
llmg_1831	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
llmg_1832	COG0318	PFAM AMP-dependent synthetase and ligase
llmg_1833	COG4948	Mandelate Racemase Muconate Lactonizing
llmg_1835	COG1609	Transcriptional regulator
llmg_1836	COG1501	Belongs to the glycosyl hydrolase 31 family
llmg_1838	COG1653	transport
llmg_1839	COG0395	ABC-type sugar transport system, permease component
llmg_1840	COG2801	Transposase and inactivated derivatives
llmg_1841	COG2963	transposase activity
llmg_1845	COG1234	tRNA 3'-trailer cleavage
llmg_1849	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
llmg_1854	COG0586	Pfam SNARE associated Golgi protein
llmg_1856	COG1132	(ABC) transporter
llmg_1860	COG1846	Transcriptional regulator
llmg_1861	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
llmg_1862	COG4988	ABC transporter
llmg_1863	COG1294	oxidase, subunit
llmg_1864	COG1271	oxidase subunit
llmg_1866	COG1266	CAAX protease self-immunity
llmg_1871	COG0058	SHG alpha-glucan phosphorylase activity
llmg_1872	COG0297	glycogen (starch) synthase activity
llmg_1873	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
llmg_1874	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
llmg_1878	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
llmg_1880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
llmg_1881	COG0006	proline dipeptidase activity
llmg_1882	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
llmg_1883	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
llmg_1885	COG0084	hydrolase, TatD family'
llmg_1886	COG0582	viral genome integration into host DNA
llmg_1890	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_1890	COG3942	CHAP domain
llmg_1893	COG2801	Transposase and inactivated derivatives
llmg_1895	COG0704	Plays a role in the regulation of phosphate uptake
llmg_1896	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
llmg_1897	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
llmg_1898	COG0581	inorganic phosphate transmembrane transporter activity
llmg_1899	COG0573	inorganic phosphate transmembrane transporter activity
llmg_1900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
llmg_1901	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
llmg_1902	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
llmg_1906	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
llmg_1907	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
llmg_1913	COG2252	PERMEase
llmg_1914	COG0561	phosphatase activity
llmg_1915	COG0247	lactate metabolic process
llmg_1916	COG1139	Iron-sulfur cluster binding protein
llmg_1917	COG1556	Lactate utilization protein
llmg_1918	COG0670	Belongs to the BI1 family
llmg_1921	COG0268	Binds directly to 16S ribosomal RNA
llmg_1922	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
llmg_1923	COG0406	alpha-ribazole phosphatase activity
llmg_1924	COG0077	Prephenate dehydratase
llmg_1925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
llmg_1926	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
llmg_1927	COG0287	Prephenate dehydrogenase
llmg_1928	COG5002	protein histidine kinase activity
llmg_1929	COG0745	RESPONSE REGULATOR receiver
llmg_1932	COG1136	(ABC) transporter
llmg_1934	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
llmg_1936	COG4493	Belongs to the UPF0637 family
llmg_1938	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
llmg_1939	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
llmg_1942	COG0765	amino acid transport
llmg_1943	COG1126	abc transporter atp-binding protein
llmg_1945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
llmg_1946	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
llmg_1947	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
llmg_1948	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
llmg_1949	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
llmg_1950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
llmg_1951	COG0356	it plays a direct role in the translocation of protons across the membrane
llmg_1955	COG1596	polysaccharide export
llmg_1955	COG1555	photosystem II stabilization
llmg_1957	COG4152	abc transporter atp-binding protein
llmg_1961	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
llmg_1964	COG1268	BioY protein
llmg_1965	COG0318	PFAM AMP-dependent synthetase and ligase
llmg_1968	COG4842	Belongs to the WXG100 family
llmg_1969	COG0719	Fe-S assembly protein
llmg_1972	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
llmg_1973	COG0719	Fe-S assembly protein
llmg_1976	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
llmg_1977	COG4862	establishment of competence for transformation
llmg_1978	COG1126	abc transporter atp-binding protein
llmg_1979	COG0765	amino acid transport
llmg_1981	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
llmg_1982	COG0085	RNA polymerase activity
llmg_1984	COG1396	sequence-specific DNA binding
llmg_1985	COG3590	peptidase
llmg_1988	COG2244	polysaccharide biosynthetic process
llmg_1989	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
llmg_1991	COG1064	alcohol dehydrogenase
llmg_1992	COG0514	ATP-dependent DNA helicase (RecQ)
llmg_1993	COG0531	amino acid
llmg_1996	COG1227	inorganic diphosphatase activity
llmg_1997	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
llmg_1999	COG1253	flavin adenine dinucleotide binding
llmg_2000	COG0628	permease
llmg_2007	COG1573	uracil-dna glycosylase
llmg_2008	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
llmg_2010	COG2827	Endonuclease containing a URI domain
llmg_2011	COG1113	amino acid transport
llmg_2013	COG1564	THIamine pyrophosphokinase
llmg_2017	COG0017	Asparaginyl-tRNA synthetase
llmg_2019	COG0436	Aminotransferase
llmg_2021	COG1199	ATP-dependent helicase activity
llmg_2021	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
llmg_2025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
llmg_2026	COG0601	transmembrane transport
llmg_2029	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
llmg_2030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
llmg_2031	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
llmg_2035	COG0445	tRNA wobble uridine modification
llmg_2039	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
llmg_2040	COG0215	cysteine-tRNA ligase activity
llmg_2042	COG1045	serine acetyltransferase
llmg_2044	COG1185	polyribonucleotide nucleotidyltransferase activity
llmg_2046	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
llmg_2047	COG0589	response to stress
llmg_2048	COG1104	cysteine desulfurase activity
llmg_2050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
llmg_2053	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
llmg_2055	COG3599	regulation of cell shape
llmg_2058	COG1799	cell septum assembly
llmg_2059	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
llmg_2060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
llmg_2061	COG0849	cell division
llmg_2062	COG1307	EDD domain protein, DegV family
llmg_2064	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
llmg_2065	COG0656	L-ascorbic acid biosynthetic process
llmg_2067	COG0583	DNA-binding transcription factor activity
llmg_2073	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
llmg_2075	COG0494	nUDIX hydrolase
llmg_2076	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
llmg_2077	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
llmg_2078	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
llmg_2079	COG2815	serine threonine protein kinase
llmg_2079	COG0515	serine threonine protein kinase
llmg_2080	COG0631	protein serine/threonine phosphatase activity
llmg_2081	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
llmg_2081	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
llmg_2114	COG0756	dUTP diphosphatase activity
llmg_2126	COG0629	single-stranded DNA binding
llmg_2128	COG4712	double-strand break repair protein
llmg_2134	COG3617	BRO family, N-terminal domain
llmg_2146	COG2261	transglycosylase associated protein
llmg_2147	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
llmg_2153	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
llmg_2154	COG1758	RNA polymerase activity
llmg_2155	COG0194	GDP metabolic process
llmg_2156	COG1418	mRNA catabolic process
llmg_2157	COG0363	glucosamine-6-phosphate deaminase activity
llmg_2159	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
llmg_2160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
llmg_2161	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
llmg_2162	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
llmg_2162	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
llmg_2165	COG1705	Flagellar rod assembly protein muramidase FlgJ
llmg_2165	COG3942	CHAP domain
llmg_2167	COG0191	fructose-bisphosphate aldolase activity
llmg_2168	COG2860	membrane
llmg_2169	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
llmg_2174	COG2801	Transposase and inactivated derivatives
llmg_2176	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
llmg_2181	COG0626	cystathionine gamma-synthase activity
llmg_2182	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
llmg_2186	COG3481	metal-dependent phosphohydrolase, HD sub domain
llmg_2187	COG1322	Protein conserved in bacteria
llmg_2189	COG1660	Displays ATPase and GTPase activities
llmg_2193	COG1162	GTPase activity
llmg_2194	COG1388	LysM domain
llmg_2194	COG3584	3D domain protein
llmg_2195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
llmg_2195	COG0072	phenylalanine-tRNA ligase activity
llmg_2196	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
llmg_2197	COG3479	Phenolic acid decarboxylase
llmg_2199	COG3469	chitinase activity
llmg_2200	COG3397	chitin binding
llmg_2201	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
llmg_2204	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
llmg_2205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
llmg_2209	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
llmg_2212	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
llmg_2213	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
llmg_2214	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
llmg_2215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
llmg_2216	COG0537	adenosine 5'-monophosphoramidase activity
llmg_2217	COG0124	histidyl-tRNA synthetase
llmg_2224	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
llmg_2225	COG1426	Protein conserved in bacteria
llmg_2226	COG0612	Peptidase, M16
llmg_2227	COG0612	Peptidase, M16
llmg_2228	COG2501	S4 domain
llmg_2229	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
llmg_2230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
llmg_2233	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
llmg_2234	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
llmg_2235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
llmg_2241	COG3172	ATPase kinase involved in NAD metabolism
llmg_2241	COG1056	cytidyltransferase-related domain
llmg_2246	COG0500	methyltransferase
llmg_2250	COG5484	DNA packaging
llmg_2250	COG3728	DNA packaging
llmg_2271	COG1131	(ABC) transporter
llmg_2272	COG0584	glycerophosphoryl diester phosphodiesterase
llmg_2273	COG0537	adenosine 5'-monophosphoramidase activity
llmg_2276	COG0081	regulation of translation
llmg_2277	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
llmg_2280	COG4479	Belongs to the UPF0346 family
llmg_2281	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
llmg_2282	COG2996	Protein conserved in bacteria
llmg_2284	COG0233	cytoplasmic translational termination
llmg_2285	COG0528	UMP kinase activity
llmg_2288	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
llmg_2289	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
llmg_2290	COG0827	DNA restriction-modification system
llmg_2299	COG1940	carbohydrate kinase activity
llmg_2302	COG0783	Belongs to the Dps family
llmg_2305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
llmg_2307	COG0531	amino acid
llmg_2308	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
llmg_2311	COG0531	amino acid
llmg_2312	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
llmg_2313	COG2235	arginine
llmg_2314	COG0018	arginyl-trna synthetase
llmg_2315	COG1438	arginine binding
llmg_2316	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
llmg_2319	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
llmg_2321	COG0028	Belongs to the TPP enzyme family
llmg_2322	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
llmg_2326	COG1266	CAAX protease self-immunity
llmg_2329	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
llmg_2330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
llmg_2331	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
llmg_2332	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
llmg_2333	COG1335	isochorismatase
llmg_2341	COG4956	integral membrane protein (PIN domain superfamily)
llmg_2344	COG1216	Glycosyl transferase, family 2
llmg_2344	COG1442	glycosyl transferase family 8
llmg_2345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
llmg_2346	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
llmg_2350	COG1216	Glycosyl transferase, family 2
llmg_2351	COG1216	Glycosyl transferase, family 2
llmg_2353	COG0203	ribosomal protein L17
llmg_2354	COG0202	RNA polymerase activity
llmg_2355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
llmg_2356	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
llmg_2357	COG0257	Belongs to the bacterial ribosomal protein bL36 family
llmg_2358	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
llmg_2362	COG0200	Binds to the 23S rRNA
llmg_2363	COG1841	ribosomal large subunit assembly
llmg_2364	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
llmg_2365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
llmg_2366	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
llmg_2367	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
llmg_2370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
llmg_2371	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
llmg_2372	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
llmg_2373	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
llmg_2374	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
llmg_2375	COG0255	Belongs to the universal ribosomal protein uL29 family
llmg_2376	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
llmg_2377	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
llmg_2378	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
llmg_2379	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
llmg_2380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
llmg_2382	COG0088	Forms part of the polypeptide exit tunnel
llmg_2383	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
llmg_2384	COG0051	transcription antitermination factor activity, RNA binding
llmg_2385	COG1970	mechanosensitive ion channel activity
llmg_2387	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
llmg_2388	COG0250	Participates in transcription elongation, termination and antitermination
llmg_2390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
llmg_2391	COG2755	lipolytic protein G-D-S-L family
llmg_2391	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
llmg_2392	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
llmg_2393	COG2323	membrane
llmg_2396	COG0564	pseudouridine synthase activity
llmg_2398	COG1108	ABC-type Mn2 Zn2 transport systems permease components
llmg_2399	COG1121	(ABC) transporter
llmg_2400	COG3443	Belongs to the bacterial solute-binding protein 9 family
llmg_2400	COG0803	Belongs to the bacterial solute-binding protein 9 family
llmg_2401	COG1846	Transcriptional regulator
llmg_2406	COG4537	Required for transformation and DNA binding
llmg_2407	COG1459	type II secretion system
llmg_2408	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
llmg_2409	COG2176	DNA-directed DNA polymerase activity
llmg_2412	COG0442	prolyl-tRNA aminoacylation
llmg_2413	COG0750	zinc metalloprotease
llmg_2414	COG4589	Belongs to the CDS family
llmg_2415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
llmg_2416	COG1862	Preprotein translocase
llmg_2418	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
llmg_2419	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
llmg_2421	COG0438	transferase activity, transferring glycosyl groups
llmg_2424	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
llmg_2425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
llmg_2425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
llmg_2428	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
llmg_2429	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
llmg_2430	COG0052	Belongs to the universal ribosomal protein uS2 family
llmg_2431	COG2706	6-phosphogluconolactonase activity
llmg_2432	COG1454	alcohol dehydrogenase
llmg_2432	COG1012	belongs to the aldehyde dehydrogenase family
llmg_2438	COG1396	sequence-specific DNA binding
llmg_2440	COG0535	radical SAM domain protein
llmg_2442	COG3480	Lon protease (S16) C-terminal proteolytic domain
llmg_2443	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
llmg_2444	COG0742	ribosomal rna small subunit methyltransferase
llmg_2445	COG2814	Major facilitator Superfamily
llmg_2448	COG0166	Belongs to the GPI family
llmg_2453	COG1733	regulation of RNA biosynthetic process
llmg_2455	COG0525	valine-tRNA ligase activity
llmg_2464	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
llmg_2466	COG2137	regulation of response to DNA damage stimulus
llmg_2468	COG1070	Carbohydrate kinase
llmg_2469	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
llmg_2472	COG1408	metallophosphoesterase
llmg_2473	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
llmg_2474	COG0629	single-stranded DNA binding
llmg_2475	COG0360	Binds together with S18 to 16S ribosomal RNA
llmg_2476	COG1968	undecaprenyl-diphosphatase activity
llmg_2477	COG0833	amino acid
llmg_2478	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
llmg_2480	COG1956	GAF domain-containing protein
llmg_2481	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
llmg_2481	COG1605	Chorismate mutase
llmg_2484	COG0174	glutamine synthetase
llmg_2485	COG0789	Transcriptional regulator
llmg_2486	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
llmg_2487	COG2255	four-way junction helicase activity
llmg_2488	COG0632	four-way junction helicase activity
llmg_2489	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
llmg_2491	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
llmg_2493	COG3328	transposase activity
llmg_2494	COG2084	Dehydrogenase
llmg_2497	COG0730	response to heat
llmg_2499	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
llmg_2500	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
llmg_2502	COG0484	heat shock protein binding
llmg_2504	COG1794	racemase activity, acting on amino acids and derivatives
llmg_2506	COG0367	asparagine synthase
llmg_2507	COG3942	CHAP domain
llmg_2507	COG3883	PFAM NLP P60 protein
llmg_2510	COG0494	nUDIX hydrolase
llmg_2511	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
llmg_2512	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
llmg_2513	COG2814	Major facilitator Superfamily
llmg_2514	COG0589	response to stress
llmg_2517	COG1309	transcriptional regulator
llmg_2518	COG1187	pseudouridine synthase activity
llmg_2521	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
llmg_2523	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
llmg_2524	COG2824	Alkylphosphonate utilization operon protein PhnA
llmg_2545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
llmg_2546	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
llmg_2548	COG1136	(ABC) transporter
llmg_2549	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
llmg_2550	COG0681	Belongs to the peptidase S26 family
llmg_2551	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
llmg_2556	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
llmg_2557	COG0049	tRNA binding
llmg_2558	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
llmg_2560	COG1686	Belongs to the peptidase S11 family
llmg_2561	COG4975	Glucose uptake
llmg_2562	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
llmg_2563	COG1242	4 iron, 4 sulfur cluster binding