locus-tag	class	description
lpp0002	COG0592	DNA-directed DNA polymerase activity
lpp0004	COG0187	DNA topoisomerase II activity
lpp0006	COG1166	arginine decarboxylase activity
lpp0010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
lpp0013	COG1741	Belongs to the pirin family
lpp0015	COG1566	PFAM secretion protein HlyD family protein
lpp0019	COG3227	Zinc metalloprotease (Elastase)
lpp0021	COG3028	Belongs to the UPF0307 family
lpp0026	COG0531	amino acid
lpp0027	COG0306	phosphate transporter
lpp0029	COG3300	MHYT domain
lpp0029	COG5001	Diguanylate cyclase
lpp0031	COG2234	aminopeptidase activity
lpp0039	COG2827	Endonuclease containing a URI domain
lpp0043	COG3781	membrane
lpp0054	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
lpp0057	COG0583	DNA-binding transcription factor activity
lpp0061	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
lpp0064	COG3550	peptidyl-serine autophosphorylation
lpp0065	COG1396	sequence-specific DNA binding
lpp0072	COG0582	viral genome integration into host DNA
lpp0078	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
lpp0087	COG2203	Gaf domain
lpp0087	COG3706	GGDEF domain
lpp0087	COG4251	negative regulation of phosphorylation
lpp0087	COG5001	Diguanylate cyclase
lpp0088	COG0069	glutamate synthase activity
lpp0089	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
lpp0090	COG3079	Belongs to the UPF0149 family
lpp0091	COG0006	proline dipeptidase activity
lpp0092	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
lpp0093	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
lpp0099	COG4067	protein conserved in archaea
lpp0099	COG0189	ligase activity
lpp0106	COG0557	exoribonuclease II activity
lpp0107	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
lpp0116	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
lpp0118	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
lpp0120	COG2252	PERMEase
lpp0127	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
lpp0136	COG1116	anion transmembrane transporter activity
lpp0141	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
lpp0144	COG3360	Dodecin
lpp0151	COG0469	pyruvate kinase activity
lpp0153	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
lpp0154	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
lpp0156	COG0339	signal peptide processing
lpp0168	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
lpp0183	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
lpp0194	COG0582	viral genome integration into host DNA
lpp0199	COG2963	transposase activity
lpp0219	COG5001	Diguanylate cyclase
lpp0220	COG2200	EAL domain
lpp0228	COG2354	Protein conserved in bacteria
lpp0229	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
lpp0238	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
lpp0239	COG2814	Major facilitator Superfamily
lpp0242	COG2226	methyltransferase
lpp0259	COG1271	oxidase subunit
lpp0260	COG1294	oxidase, subunit
lpp0263	COG1307	EDD domain protein, DegV family
lpp0264	COG1028	Short-chain dehydrogenase reductase Sdr
lpp0271	COG0415	Belongs to the DNA photolyase family
lpp0272	COG1346	cytolysis
lpp0273	COG1380	Effector of murein hydrolase LrgA
lpp0274	COG0583	DNA-binding transcription factor activity
lpp0281	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
lpp0282	COG0583	DNA-binding transcription factor activity
lpp0287	COG0531	amino acid
lpp0291	COG1028	Short-chain dehydrogenase reductase Sdr
lpp0292	COG0477	Major facilitator Superfamily
lpp0294	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
lpp0295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
lpp0296	COG1845	cytochrome c oxidase, subunit III
lpp0297	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
lpp0299	COG3706	GGDEF domain
lpp0302	COG0735	belongs to the Fur family
lpp0304	COG1196	nuclear chromosome segregation
lpp0312	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
lpp0318	COG1393	Belongs to the ArsC family
lpp0320	COG0513	Belongs to the DEAD box helicase family
lpp0322	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
lpp0327	COG1566	PFAM secretion protein HlyD family protein
lpp0331	COG2827	Endonuclease containing a URI domain
lpp0333	COG1573	uracil-dna glycosylase
lpp0341	COG0598	Magnesium transport protein CorA
lpp0343	COG0433	COG0433 Predicted ATPase
lpp0344	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
lpp0345	COG1335	isochorismatase
lpp0347	COG2814	Major facilitator Superfamily
lpp0348	COG0583	DNA-binding transcription factor activity
lpp0355	COG0583	DNA-binding transcription factor activity
lpp0358	COG2226	methyltransferase
lpp0362	COG4221	oxidoreductase activity
lpp0366	COG1509	lysine 2,3-aminomutase activity
lpp0381	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
lpp0422	COG2814	Major facilitator Superfamily
lpp0423	COG1028	Short-chain dehydrogenase reductase Sdr
lpp0424	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
lpp0425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
lpp0426	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
lpp0428	COG1560	Kdo2-lipid A biosynthetic process
lpp0435	COG2867	negative regulation of translational initiation
lpp0440	COG2199	diguanylate cyclase activity
lpp0440	COG2203	Gaf domain
lpp0452	COG1704	LemA family
lpp0453	COG0501	Belongs to the peptidase M48B family
lpp0454	COG0842	Transport permease protein
lpp0455	COG1131	(ABC) transporter
lpp0467	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
lpp0470	COG0531	amino acid
lpp0474	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
lpp0478	COG1612	heme a metabolic process
lpp0480	COG1999	signal sequence binding
lpp0483	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
lpp0484	COG0363	glucosamine-6-phosphate deaminase activity
lpp0485	COG0129	dihydroxy-acid dehydratase activity
lpp0487	COG0800	Aldolase
lpp0497	COG1566	PFAM secretion protein HlyD family protein
lpp0523	COG0477	Major facilitator Superfamily
lpp0528	COG0439	Biotin carboxylase
lpp0529	COG0511	ligase activity, forming carbon-carbon bonds
lpp0534	COG3568	Endonuclease Exonuclease Phosphatase
lpp0535	COG3588	fructose-bisphosphate aldolase
lpp0539	COG1183	phosphatidylcholine synthase activity
lpp0542	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
lpp0546	COG1363	Peptidase, m42
lpp0548	COG0330	HflC and HflK could
lpp0549	COG0330	HflC and HflK could
lpp0553	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
lpp0554	COG0765	amino acid transport
lpp0555	COG1126	abc transporter atp-binding protein
lpp0558	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
lpp0562	COG4942	peptidase
lpp0567	COG0575	Belongs to the CDS family
lpp0571	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
lpp0573	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
lpp0593	COG2009	succinate dehydrogenase
lpp0594	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
lpp0595	COG1053	succinate dehydrogenase
lpp0596	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
lpp0600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
lpp0613	COG2076	Multidrug Resistance protein
lpp0621	COG1028	Short-chain dehydrogenase reductase Sdr
lpp0625	COG2715	membrane protein required for spore maturation
lpp0626	COG0700	Nucleoside recognition
lpp0627	COG0739	heme binding
lpp0629	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
lpp0630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
lpp0631	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
lpp0633	COG0306	phosphate transporter
lpp0634	COG1392	Phosphate transport regulator
lpp0640	COG0606	chelatase, subunit chli
lpp0642	COG0347	Belongs to the P(II) protein family
lpp0643	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
lpp0650	COG3243	poly(R)-hydroxyalkanoic acid synthase
lpp0652	COG0719	Fe-S assembly protein
lpp0653	COG0396	ATPase activity
lpp0654	COG0719	Fe-S assembly protein
lpp0655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
lpp0656	COG0822	iron-sulfur transferase activity
lpp0657	COG2151	metal-sulfur cluster biosynthetic enzyme
lpp0658	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
lpp0659	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
lpp0662	COG1253	flavin adenine dinucleotide binding
lpp0663	COG1064	alcohol dehydrogenase
lpp0672	COG0519	Catalyzes the synthesis of GMP from XMP
lpp0701	COG2852	Protein conserved in bacteria
lpp0702	COG0708	Exodeoxyribonuclease III
lpp0703	COG0708	Exodeoxyribonuclease III
lpp0705	COG0281	malic enzyme
lpp0708	COG0338	D12 class N6 adenine-specific DNA methyltransferase
lpp0710	COG0814	amino acid
lpp0713	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
lpp0714	COG1131	(ABC) transporter
lpp0718	COG0842	Transport permease protein
lpp0721	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
lpp0724	COG3220	belongs to the UPF0276 family
lpp0728	COG4689	acetoacetate decarboxylase
lpp0732	COG3220	belongs to the UPF0276 family
lpp0735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
lpp0738	COG1131	(ABC) transporter
lpp0741	COG4232	protein-disulfide reductase activity
lpp0744	COG0783	Belongs to the Dps family
lpp0746	COG0187	DNA topoisomerase II activity
lpp0750	COG0666	response to abiotic stimulus
lpp0750	COG3177	Filamentation induced by cAMP protein fic
lpp0751	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
lpp0754	COG1538	Outer membrane efflux protein
lpp0755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
lpp0758	COG0488	(ABC) transporter
lpp0768	COG1297	OPT oligopeptide transporter protein
lpp0771	COG3293	Transposase
lpp0781	COG0745	RESPONSE REGULATOR receiver
lpp0786	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
lpp0794	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
lpp0795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
lpp0796	COG0628	permease
lpp0801	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
lpp0803	COG0305	Participates in initiation and elongation during chromosome replication
lpp0809	COG3706	GGDEF domain
lpp0811	COG2827	Endonuclease containing a URI domain
lpp0812	COG3104	oligopeptide transport
lpp0815	COG0107	imidazoleglycerol-phosphate synthase activity
lpp0817	COG1083	cytidylyl-transferase
lpp0818	COG2089	acid synthase
lpp0819	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
lpp0821	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
lpp0824	COG1088	dTDP-glucose 4,6-dehydratase activity
lpp0828	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
lpp0834	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
lpp0847	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
lpp0847	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
lpp0848	COG2091	lysine biosynthetic process via aminoadipic acid
lpp0850	COG0037	tRNA processing
lpp0853	COG1696	Membrane protein involved in D-alanine export
lpp0854	COG1760	l-serine dehydratase
lpp0855	COG0545	Peptidyl-prolyl cis-trans isomerase
lpp0856	COG2223	nitrite transmembrane transporter activity
lpp0857	COG2963	transposase activity
lpp0862	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
lpp0863	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
lpp0864	COG0659	secondary active sulfate transmembrane transporter activity
lpp0865	COG1960	acyl-CoA dehydrogenase activity
lpp0867	COG0574	Belongs to the PEP-utilizing enzyme family
lpp0867	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
lpp0868	COG0475	glutathione-regulated potassium exporter activity
lpp0871	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
lpp0872	COG1555	photosystem II stabilization
lpp0874	COG1792	Involved in formation and maintenance of cell shape
lpp0875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
lpp0876	COG1187	pseudouridine synthase activity
lpp0882	COG2827	Endonuclease containing a URI domain
lpp0886	COG0705	Rhomboid family
lpp0887	COG0739	heme binding
lpp0897	COG0512	Glutamine amidotransferase of anthranilate synthase
lpp0898	COG1137	ATPase activity
lpp0901	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
lpp0903	COG1127	ABC transporter
lpp0904	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
lpp0905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
lpp0908	COG5007	Belongs to the BolA IbaG family
lpp0911	COG1136	(ABC) transporter
lpp0912	COG0577	efflux transmembrane transporter activity
lpp0913	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
lpp0915	COG2204	response regulator
lpp0917	COG0616	signal peptide processing
lpp0923	COG1138	Cytochrome C-type biogenesis protein
lpp0927	COG3360	Dodecin
lpp0930	COG0514	ATP-dependent DNA helicase (RecQ)
lpp0931	COG1960	acyl-CoA dehydrogenase activity
lpp0932	COG1024	Enoyl-CoA hydratase
lpp0933	COG1024	Enoyl-CoA hydratase
lpp0937	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
lpp0938	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
lpp0939	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
lpp0942	COG3706	GGDEF domain
lpp0951	COG0626	cystathionine gamma-synthase activity
lpp0960	COG1194	a g-specific adenine glycosylase
lpp0965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
lpp0970	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
lpp0980	COG1994	Peptidase M50
lpp0986	COG0686	Belongs to the AlaDH PNT family
lpp0997	COG0589	response to stress
lpp0998	COG0196	riboflavin kinase activity
lpp1001	COG0800	Aldolase
lpp1004	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
lpp1009	COG0674	pyruvate-flavodoxin oxidoreductase activity
lpp1009	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
lpp1010	COG1013	pyruvate-flavodoxin oxidoreductase activity
lpp1012	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
lpp1013	COG0312	modulator of DNA gyrase
lpp1016	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
lpp1022	COG0601	transmembrane transport
lpp1023	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
lpp1026	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
lpp1032	COG0833	amino acid
lpp1038	COG2135	peptidase activity
lpp1045	COG0629	single-stranded DNA binding
lpp1088	COG0582	viral genome integration into host DNA
lpp1091	COG3177	Filamentation induced by cAMP protein fic
lpp1093	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
lpp1104	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
lpp1104	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
lpp1106	COG4325	translation initiation factor activity
lpp1115	COG4251	negative regulation of phosphorylation
lpp1123	COG1388	LysM domain
lpp1123	COG0741	lytic transglycosylase activity
lpp1126	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
lpp1129	COG0590	tRNA wobble adenosine to inosine editing
lpp1133	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
lpp1135	COG2070	2-Nitropropane dioxygenase
lpp1140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
lpp1141	COG1177	transmembrane transport
lpp1142	COG1176	ABC-type spermidine putrescine transport system, permease component I
lpp1148	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
lpp1155	COG1231	oxidoreductase activity
lpp1157	COG3961	Belongs to the TPP enzyme family
lpp1161	COG0697	spore germination
lpp1166	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
lpp1171	COG1355	regulation of microtubule-based process
lpp1179	COG4783	chaperone-mediated protein folding
lpp1180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
lpp1180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
lpp1181	COG0307	riboflavin synthase, alpha
lpp1182	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
lpp1182	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
lpp1187	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
lpp1192	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
lpp1193	COG1472	Belongs to the glycosyl hydrolase 3 family
lpp1195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
lpp1195	COG0140	phosphoribosyl-ATP diphosphatase activity
lpp1196	COG0107	imidazoleglycerol-phosphate synthase activity
lpp1202	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
lpp1207	COG1278	Cold shock
lpp1210	COG1846	Transcriptional regulator
lpp1224	COG1815	bacterial-type flagellum-dependent cell motility
lpp1225	COG1558	bacterial-type flagellum-dependent cell motility
lpp1226	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
lpp1227	COG1749	Flagellar hook protein flgE
lpp1228	COG4787	bacterial-type flagellum-dependent cell motility
lpp1238	COG3273	potassium ion transport
lpp1238	COG0471	metal ion transport
lpp1243	COG0281	malic enzyme
lpp1254	COG0642	Histidine kinase
lpp1255	COG0745	RESPONSE REGULATOR receiver
lpp1257	COG0741	lytic transglycosylase activity
lpp1257	COG1388	LysM domain
lpp1259	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
lpp1265	COG1090	epimerase
lpp1270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
lpp1276	COG0673	inositol 2-dehydrogenase activity
lpp1277	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
lpp1278	COG2814	Major facilitator Superfamily
lpp1279	COG2814	Major facilitator Superfamily
lpp1280	COG4264	IucA IucC family
lpp1296	COG0285	dihydrofolate synthase activity
lpp1298	COG1286	toxin biosynthetic process
lpp1303	COG0815	Transfers the fatty acyl group on membrane lipoproteins
lpp1305	COG1012	belongs to the aldehyde dehydrogenase family
lpp1306	COG1250	3-hydroxyacyl-CoA dehydrogenase
lpp1306	COG1024	Enoyl-CoA hydratase
lpp1307	COG0183	Belongs to the thiolase family
lpp1312	COG3156	type II secretion system protein K
lpp1316	COG2165	general secretion pathway protein
lpp1318	COG0174	glutamine synthetase
lpp1321	COG2515	1-aminocyclopropane-1-carboxylate deaminase
lpp1326	COG0673	inositol 2-dehydrogenase activity
lpp1328	COG0772	Belongs to the SEDS family
lpp1329	COG0768	penicillin binding
lpp1337	COG1028	Short-chain dehydrogenase reductase Sdr
lpp1339	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
lpp1348	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
lpp1349	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
lpp1350	COG1028	Short-chain dehydrogenase reductase Sdr
lpp1351	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
lpp1352	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
lpp1353	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
lpp1355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
lpp1357	COG0084	hydrolase, TatD family'
lpp1361	COG0463	Glycosyl transferase, family 2
lpp1367	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
lpp1369	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
lpp1370	COG0372	Belongs to the citrate synthase family
lpp1375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
lpp1378	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
lpp1382	COG4221	oxidoreductase activity
lpp1389	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
lpp1393	COG0745	RESPONSE REGULATOR receiver
lpp1394	COG4535	Mg2 and Co2 transporter CorC
lpp1396	COG1702	phosphate starvation-inducible protein PhoH
lpp1397	COG0613	PHP domain protein
lpp1398	COG0009	L-threonylcarbamoyladenylate synthase
lpp1399	COG0180	Tryptophanyl-tRNA synthetase
lpp1401	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
lpp1402	COG1187	pseudouridine synthase activity
lpp1413	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
lpp1415	COG0436	Aminotransferase
lpp1417	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
lpp1418	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
lpp1420	COG0494	nUDIX hydrolase
lpp1425	COG2200	EAL domain
lpp1427	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
lpp1429	COG0156	8-amino-7-oxononanoate synthase activity
lpp1435	COG3264	Mechanosensitive ion channel
lpp1435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
lpp1453	COG1196	nuclear chromosome segregation
lpp1454	COG0308	aminopeptidase N
lpp1459	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
lpp1463	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
lpp1464	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
lpp1464	COG0475	glutathione-regulated potassium exporter activity
lpp1465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
lpp1466	COG1686	Belongs to the peptidase S11 family
lpp1468	COG2921	Belongs to the UPF0250 family
lpp1470	COG0586	Pfam SNARE associated Golgi protein
lpp1472	COG3034	peptidoglycan biosynthetic process
lpp1473	COG2274	protein secretion by the type I secretion system
lpp1475	COG2203	Gaf domain
lpp1475	COG3706	GGDEF domain
lpp1475	COG4251	negative regulation of phosphorylation
lpp1475	COG5001	Diguanylate cyclase
lpp1479	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
lpp1481	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
lpp1487	COG0372	Belongs to the citrate synthase family
lpp1494	COG0861	Integral membrane protein TerC family
lpp1495	COG0617	tRNA 3'-terminal CCA addition
lpp1496	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
lpp1497	COG0589	response to stress
lpp1503	COG3063	Type IV pilus biogenesis stability protein PilW
lpp1509	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
lpp1510	COG0850	regulation of cytokinetic process
lpp1511	COG0318	PFAM AMP-dependent synthetase and ligase
lpp1512	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
lpp1514	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
lpp1518	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
lpp1518	COG3264	Mechanosensitive ion channel
lpp1526	COG0352	thiamine-phosphate diphosphorylase activity
lpp1540	COG1376	ErfK ybiS ycfS ynhG family protein
lpp1541	COG1012	belongs to the aldehyde dehydrogenase family
lpp1553	COG1376	ErfK ybiS ycfS ynhG family protein
lpp1553	COG1388	LysM domain
lpp1554	COG1024	Enoyl-CoA hydratase
lpp1554	COG1250	3-hydroxyacyl-CoA dehydrogenase
lpp1555	COG0183	Belongs to the thiolase family
lpp1572	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
lpp1573	COG0494	nUDIX hydrolase
lpp1575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
lpp1578	COG2852	Protein conserved in bacteria
lpp1582	COG0789	Transcriptional regulator
lpp1585	COG1132	(ABC) transporter
lpp1589	COG0768	penicillin binding
lpp1594	COG0429	hydrolase of the alpha beta-hydrolase fold
lpp1601	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
lpp1602	COG0438	transferase activity, transferring glycosyl groups
lpp1604	COG0277	FAD linked oxidase domain protein
lpp1604	COG0247	lactate metabolic process
lpp1608	COG0477	Major facilitator Superfamily
lpp1610	COG2119	membrane
lpp1611	COG0823	Involved in the tonB-independent uptake of proteins
lpp1617	COG3038	cytochrome b561
lpp1620	COG1082	Xylose isomerase domain protein TIM barrel
lpp1622	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
lpp1623	COG0673	inositol 2-dehydrogenase activity
lpp1629	COG0531	amino acid
lpp1635	COG4953	penicillin-binding protein 1C
lpp1644	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
lpp1645	COG0151	Belongs to the GarS family
lpp1650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
lpp1653	COG4232	protein-disulfide reductase activity
lpp1657	COG3144	bacterial-type flagellum assembly
lpp1660	COG0531	amino acid
lpp1668	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
lpp1669	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
lpp1671	COG3138	arginine N-succinyltransferase
lpp1684	COG0024	Methionine aminopeptidase
lpp1686	COG0590	tRNA wobble adenosine to inosine editing
lpp1689	COG2894	cell division
lpp1696	COG1175	transmembrane transport
lpp1697	COG1063	alcohol dehydrogenase
lpp1698	COG0038	chloride channel
lpp1699	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
lpp1699	COG0512	Glutamine amidotransferase of anthranilate synthase
lpp1700	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
lpp1703	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
lpp1711	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
lpp1713	COG0616	signal peptide processing
lpp1717	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
lpp1723	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
lpp1727	COG3852	Histidine kinase
lpp1728	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
lpp1730	COG1674	ftsk spoiiie
lpp1731	COG0492	ferredoxin-NADP+ reductase activity
lpp1733	COG0425	Belongs to the sulfur carrier protein TusA family
lpp1733	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
lpp1745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
lpp1752	COG1987	bacterial-type flagellum assembly
lpp1760	COG0583	DNA-binding transcription factor activity
lpp1770	COG2911	Protein conserved in bacteria
lpp1774	COG0527	aspartate kinase activity
lpp1775	COG1074	ATP-dependent DNA helicase activity
lpp1776	COG0489	protein tyrosine kinase activity
lpp1778	COG0583	DNA-binding transcription factor activity
lpp1787	COG1960	acyl-CoA dehydrogenase activity
lpp1790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
lpp1791	COG1024	Enoyl-CoA hydratase
lpp1794	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
lpp1797	COG2011	ABC-type metal ion transport system permease component
lpp1802	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
lpp1803	COG0751	glycine-tRNA ligase activity
lpp1806	COG0210	DNA helicase
lpp1812	COG2827	Endonuclease containing a URI domain
lpp1817	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
lpp1819	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
lpp1820	COG0572	uridine kinase
lpp1827	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
lpp1838	COG2951	lytic endotransglycosylase activity
lpp1840	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
lpp1846	COG0346	lactoylglutathione lyase activity
lpp1852	COG2827	Endonuclease containing a URI domain
lpp1860	COG2223	nitrite transmembrane transporter activity
lpp1861	COG0038	chloride channel
lpp1865	COG3012	SEC-C Motif Domain Protein
lpp1869	COG2852	Protein conserved in bacteria
lpp1871	COG0714	Associated with various cellular activities
lpp1874	COG2850	peptidyl-arginine hydroxylation
lpp1881	COG3101	peptidyl-lysine hydroxylation
lpp1883	COG0625	glutathione transferase activity
lpp1892	COG0531	amino acid
lpp1896	COG1214	PFAM Peptidase M22, glycoprotease
lpp1897	COG1199	ATP-dependent helicase activity
lpp1898	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
lpp1903	COG2313	pseudouridylate synthase activity
lpp1923	COG1250	3-hydroxyacyl-CoA dehydrogenase
lpp1926	COG5212	phosphodiesterase
lpp1934	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
lpp1938	COG4948	Mandelate Racemase Muconate Lactonizing
lpp1944	COG2827	Endonuclease containing a URI domain
lpp1949	COG1309	transcriptional regulator
lpp1953	COG0625	glutathione transferase activity
lpp1954	COG1764	response to oxidative stress
lpp1961	COG3774	pathogenesis
lpp1969	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
lpp1975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
lpp1981	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
lpp1982	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
lpp1983	COG1862	Preprotein translocase
lpp1984	COG0343	queuine tRNA-ribosyltransferase activity
lpp1988	COG3577	Aspartyl protease
lpp1990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
lpp1993	COG1561	YicC-like family, N-terminal region
lpp2005	COG0505	Belongs to the CarA family
lpp2009	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
lpp2011	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
lpp2017	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
lpp2021	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
lpp2025	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
lpp2026	COG2885	chlorophyll binding
lpp2027	COG3218	ABC-type transport auxiliary lipoprotein component
lpp2029	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
lpp2030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
lpp2041	COG1278	Cold shock
lpp2042	COG0513	Belongs to the DEAD box helicase family
lpp2051	COG2827	Endonuclease containing a URI domain
lpp2060	COG0583	DNA-binding transcription factor activity
lpp2062	COG1196	nuclear chromosome segregation
lpp2072	COG0477	Major facilitator Superfamily
lpp2074	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
lpp2078	COG0259	pyridoxamine-phosphate oxidase activity
lpp2079	COG1733	regulation of RNA biosynthetic process
lpp2085	COG5507	3-demethylubiquinone-9 3-methyltransferase
lpp2095	COG1196	nuclear chromosome segregation
lpp2110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
lpp2123	COG0582	viral genome integration into host DNA
lpp2131	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
lpp2132	COG0784	Response regulator, receiver
lpp2132	COG2205	protein histidine kinase activity
lpp2133	COG5002	protein histidine kinase activity
lpp2133	COG2198	Histidine kinase
lpp2133	COG0784	Response regulator, receiver
lpp2138	COG0861	Integral membrane protein TerC family
lpp2143	COG0288	reversible hydration of carbon dioxide
lpp2148	COG3104	oligopeptide transport
lpp2159	COG0604	alcohol dehydrogenase
lpp2165	COG1090	epimerase
lpp2170	COG4638	Rieske (2fe-2S)
lpp2173	COG2171	N-acyltransferase activity
lpp2178	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
lpp2180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
lpp2182	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
lpp2184	COG1028	Short-chain dehydrogenase reductase Sdr
lpp2185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
lpp2186	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
lpp2190	COG1132	(ABC) transporter
lpp2199	COG1301	dicarboxylic acid transport
lpp2201	COG0586	Pfam SNARE associated Golgi protein
lpp2203	COG0519	Catalyzes the synthesis of GMP from XMP
lpp2206	COG0174	glutamine synthetase
lpp2208	COG3220	belongs to the UPF0276 family
lpp2210	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
lpp2214	COG3243	poly(R)-hydroxyalkanoic acid synthase
lpp2216	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
lpp2228	COG0584	glycerophosphoryl diester phosphodiesterase
lpp2232	COG3185	4-Hydroxyphenylpyruvate dioxygenase
lpp2234	COG0625	glutathione transferase activity
lpp2239	COG4591	ABC-type transport system involved in lipoprotein release permease component
lpp2241	COG0546	phosphoglycolate phosphatase activity
lpp2242	COG0564	pseudouridine synthase activity
lpp2244	COG1530	ribonuclease E activity
lpp2247	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
lpp2250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
lpp2252	COG2890	protein-(glutamine-N5) methyltransferase activity
lpp2253	COG1193	negative regulation of DNA recombination
lpp2254	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
lpp2262	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
lpp2264	COG1028	Short-chain dehydrogenase reductase Sdr
lpp2269	COG0814	amino acid
lpp2278	COG0142	geranyltranstransferase activity
lpp2279	COG2226	methyltransferase
lpp2280	COG1040	competence protein
lpp2285	COG2890	protein-(glutamine-N5) methyltransferase activity
lpp2288	COG1519	Transferase
lpp2289	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
lpp2291	COG3240	lipase activity
lpp2294	COG0513	Belongs to the DEAD box helicase family
lpp2295	COG1597	lipid kinase activity
lpp2296	COG0446	pyridine nucleotide-disulphide oxidoreductase
lpp2296	COG1902	pentaerythritol trinitrate reductase activity
lpp2297	COG2032	superoxide dismutase activity
lpp2299	COG0450	alkyl hydroperoxide reductase
lpp2302	COG0494	nUDIX hydrolase
lpp2303	COG0635	Involved in the biosynthesis of porphyrin-containing compound
lpp2304	COG0154	amidase activity
lpp2309	COG0358	DNA primase activity
lpp2314	COG0477	Major facilitator Superfamily
lpp2316	COG0596	Alpha beta hydrolase
lpp2321	COG1278	Cold shock
lpp2322	COG1028	Short-chain dehydrogenase reductase Sdr
lpp2328	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
lpp2333	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
lpp2333	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
lpp2337	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
lpp2344	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
lpp2345	COG2132	Multicopper oxidase
lpp2355	COG2203	Gaf domain
lpp2355	COG2199	diguanylate cyclase activity
lpp2356	COG2217	Heavy metal translocating P-type atpase
lpp2360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
lpp2361	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
lpp2364	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
lpp2370	COG2217	Heavy metal translocating P-type atpase
lpp2378	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
lpp2421	COG1943	Transposase
lpp2435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
lpp2453	COG0531	amino acid
lpp2473	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
lpp2477	COG0745	RESPONSE REGULATOR receiver
lpp2477	COG3706	GGDEF domain
lpp2507	COG0435	Glutathione S-transferase
lpp2514	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
lpp2523	COG4565	transcriptional regulatory protein
lpp2524	COG4251	negative regulation of phosphorylation
lpp2539	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
lpp2543	COG0463	Glycosyl transferase, family 2
lpp2545	COG0697	spore germination
lpp2547	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
lpp2550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
lpp2552	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
lpp2557	COG0517	IMP dehydrogenase activity
lpp2562	COG5310	Homospermidine synthase
lpp2563	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
lpp2570	COG0477	Major facilitator Superfamily
lpp2574	COG2205	protein histidine kinase activity
lpp2574	COG0784	Response regulator, receiver
lpp2577	COG1196	nuclear chromosome segregation
lpp2581	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
lpp2585	COG1522	sequence-specific DNA binding
lpp2595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
lpp2597	COG1605	Chorismate mutase
lpp2597	COG0077	Prephenate dehydratase
lpp2598	COG0436	Aminotransferase
lpp2600	COG1959	2 iron, 2 sulfur cluster binding
lpp2616	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
lpp2621	COG0697	spore germination
lpp2628	COG3189	MarR family transcriptional regulator
lpp2632	COG1960	acyl-CoA dehydrogenase activity
lpp2638	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
lpp2643	COG1475	DNA binding
lpp2650	COG0758	DNA mediated transformation
lpp2653	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
lpp2653	COG2755	lipolytic protein G-D-S-L family
lpp2660	COG3590	peptidase
lpp2662	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
lpp2668	COG0772	Belongs to the SEDS family
lpp2671	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
lpp2672	COG3115	cell septum assembly
lpp2673	COG1196	nuclear chromosome segregation
lpp2678	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
lpp2680	COG2081	HI0933 family
lpp2683	COG0795	lipopolysaccharide-transporting ATPase activity
lpp2685	COG2927	DNA polymerase III (CHI subunit)
lpp2687	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
lpp2694	COG1376	ErfK ybiS ycfS ynhG family protein
lpp2699	COG2197	response regulator
lpp2707	COG0012	GTP binding
lpp2713	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
lpp2718	COG0439	Biotin carboxylase
lpp2722	COG2177	Part of the ABC transporter FtsEX involved in
lpp2723	COG2884	Cell division ATP-binding protein ftsE
lpp2724	COG0552	protein localization to endoplasmic reticulum
lpp2725	COG0612	Peptidase, M16
lpp2726	COG0612	Peptidase, M16
lpp2727	COG0742	ribosomal rna small subunit methyltransferase
lpp2731	COG4085	toxin activity
lpp2731	COG0737	Belongs to the 5'-nucleotidase family
lpp2731	COG1525	nuclease
lpp2732	COG2226	methyltransferase
lpp2737	COG0473	3-isopropylmalate dehydrogenase activity
lpp2737	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
lpp2745	COG2608	mercury ion transmembrane transporter activity
lpp2745	COG2217	Heavy metal translocating P-type atpase
lpp2747	COG2226	methyltransferase
lpp2749	COG0859	PFAM glycosyl transferase family 9
lpp2753	COG0860	N-Acetylmuramoyl-L-alanine amidase
lpp2754	COG0802	atpase or kinase
lpp2755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
lpp2755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
lpp2756	COG2969	positive regulation of protein catabolic process
lpp2757	COG0625	glutathione transferase activity
lpp2758	COG2857	Cytochrome c1
lpp2759	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
lpp2760	COG0723	plastoquinol--plastocyanin reductase activity
lpp2764	COG0776	regulation of translation
lpp2780	COG0640	Transcriptional regulator
lpp2782	COG2860	membrane
lpp2783	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
lpp2784	COG0343	queuine tRNA-ribosyltransferase activity
lpp2787	COG0156	8-amino-7-oxononanoate synthase activity
lpp2796	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
lpp2802	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
lpp2811	COG4536	flavin adenine dinucleotide binding
lpp2812	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
lpp2813	COG0537	adenosine 5'-monophosphoramidase activity
lpp2821	COG2251	uridine kinase activity
lpp2821	COG0195	Participates in both transcription termination and antitermination
lpp2830	COG1034	ATP synthesis coupled electron transport
lpp2831	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
lpp2841	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
lpp2842	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
lpp2844	COG1534	Rna-binding protein
lpp2848	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
lpp2855	COG0308	aminopeptidase N
lpp2856	COG2766	serine protein kinase
lpp2860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
lpp2862	COG0583	DNA-binding transcription factor activity
lpp2868	COG0210	DNA helicase
lpp2870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
lpp2873	COG0667	Aldo Keto reductase
lpp2877	COG0497	DNA recombination
lpp2880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
lpp2890	COG1607	acyl-coa hydrolase
lpp2891	COG2183	response to ionizing radiation
lpp2896	COG2827	Endonuclease containing a URI domain
lpp2899	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
lpp2900	COG0477	Major facilitator Superfamily
lpp2917	COG0714	Associated with various cellular activities
lpp2924	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
lpp2929	COG0730	response to heat
lpp2930	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
lpp2932	COG0252	asparaginase activity
lpp2935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
lpp2937	COG0598	Magnesium transport protein CorA
lpp2939	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
lpp2940	COG2878	Part of a membrane complex involved in electron transport
lpp2946	COG0662	Cupin 2, conserved barrel domain protein
lpp2946	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
lpp2950	COG1192	Involved in chromosome partitioning
lpp2951	COG1475	DNA binding
lpp2953	COG3293	Transposase
lpp2956	COG0519	Catalyzes the synthesis of GMP from XMP
lpp2959	COG1845	cytochrome c oxidase, subunit III
lpp2960	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
lpp2962	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
lpp2972	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
lpp2989	COG1136	(ABC) transporter
lpp2989	COG0577	efflux transmembrane transporter activity
lpp2997	COG0805	protein transport
lpp3000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
lpp3000	COG0543	2 iron, 2 sulfur cluster binding
lpp3004	COG1385	rRNA (uridine-N3-)-methyltransferase activity
lpp3012	COG1560	Kdo2-lipid A biosynthetic process
lpp3019	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
lpp3028	COG0330	HflC and HflK could
lpp3034	COG2885	chlorophyll binding
lpp3034	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
lpp3036	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
lpp3038	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
lpp3040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
lpp3041	COG1234	tRNA 3'-trailer cleavage
lpp3043	COG0281	malic enzyme
lpp3044	COG0009	L-threonylcarbamoyladenylate synthase
lpp3049	COG3227	Zinc metalloprotease (Elastase)
lpp3059	COG0356	it plays a direct role in the translocation of protons across the membrane
lpp3062	COG2823	Periplasmic or secreted lipoprotein
lpp3063	COG2823	Periplasmic or secreted lipoprotein
lpp3064	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
lpp3066	COG3107	peptidoglycan biosynthetic process
lpp3067	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
plpp0002	COG1192	Involved in chromosome partitioning
plpp0006	COG3104	oligopeptide transport
plpp0012	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
plpp0016	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
plpp0054	COG1132	(ABC) transporter
plpp0067	COG1132	(ABC) transporter
plpp0069	COG0456	acetyltransferase
plpp0069	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
plpp0073	COG0789	Transcriptional regulator
plpp0081	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
plpp0088	COG0789	Transcriptional regulator
plpp0097	COG0745	RESPONSE REGULATOR receiver
plpp0099	COG2205	protein histidine kinase activity
plpp0102	COG1872	DUF167
plpp0104	COG2378	regulation of single-species biofilm formation
plpp0111	COG1280	lysine exporter protein (LysE YggA)
plpp0123	COG1619	proteins homologs of microcin C7 resistance protein MccF
plpp0131	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
plpp0132	COG0442	prolyl-tRNA aminoacylation
plpp0134	COG1396	sequence-specific DNA binding
plpp0135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
plpp0139	COG2137	regulation of response to DNA damage stimulus
plpp0140	COG4974	Belongs to the 'phage' integrase family