locus-tag class description CPQ89_00005 COG0626 cystathionine gamma-synthase activity CPQ89_00010 COG0031 Belongs to the cysteine synthase cystathionine beta- synthase family CPQ89_00075 COG2801 Transposase and inactivated derivatives CPQ89_00085 COG0531 amino acid CPQ89_00090 COG1902 pentaerythritol trinitrate reductase activity CPQ89_00120 COG2814 Major facilitator Superfamily CPQ89_00135 COG2040 homocysteine CPQ89_00145 COG0350 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated CPQ89_00150 COG2723 6-phospho-beta-galactosidase activity CPQ89_00155 COG2188 Transcriptional regulator CPQ89_00175 COG2274 protein secretion by the type I secretion system CPQ89_00240 COG1249 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family CPQ89_00280 COG0446 pyridine nucleotide-disulphide oxidoreductase CPQ89_00290 COG2826 transposase and inactivated derivatives, IS30 family CPQ89_00325 COG0096 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit CPQ89_00405 COG1335 isochorismatase CPQ89_00465 COG1011 Hydrolase CPQ89_00490 COG2755 lipolytic protein G-D-S-L family CPQ89_00490 COG1835 transferase activity, transferring acyl groups other than amino-acyl groups CPQ89_00515 COG0488 (ABC) transporter CPQ89_00520 COG0542 response to heat CPQ89_00525 COG4463 regulation of RNA biosynthetic process CPQ89_00550 COG3279 Response regulator of the LytR AlgR family CPQ89_00560 COG1131 (ABC) transporter CPQ89_00595 COG0449 glutamine-fructose-6-phosphate transaminase (isomerizing) activity CPQ89_00610 COG4668 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_00615 COG2213 PTS system mannitol-specific CPQ89_00670 COG1063 alcohol dehydrogenase CPQ89_00705 COG1733 regulation of RNA biosynthetic process CPQ89_00745 COG2003 Belongs to the UPF0758 family CPQ89_00770 COG0588 phosphoglycerate mutase activity CPQ89_00775 COG1168 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities CPQ89_00780 COG0628 permease CPQ89_00785 COG2017 converts alpha-aldose to the beta-anomer CPQ89_00795 COG1087 Belongs to the NAD(P)-dependent epimerase dehydratase family CPQ89_00800 COG2188 Transcriptional regulator CPQ89_00810 COG1122 ATPase activity CPQ89_00820 COG0282 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction CPQ89_00825 COG3957 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase CPQ89_00830 COG0406 alpha-ribazole phosphatase activity CPQ89_00840 COG2217 Heavy metal translocating P-type atpase CPQ89_00855 COG1116 anion transmembrane transporter activity CPQ89_00865 COG2244 polysaccharide biosynthetic process CPQ89_00905 COG3853 Toxic anion resistance protein (TelA) CPQ89_00915 COG3693 PFAM glycoside hydrolase, family 10 CPQ89_00915 COG3507 Belongs to the glycosyl hydrolase 43 family CPQ89_00915 COG2382 esterase CPQ89_00925 COG1309 transcriptional regulator CPQ89_00930 COG2376 Dihydroxyacetone kinase CPQ89_00935 COG2376 Dihydroxyacetone kinase CPQ89_01015 COG0270 DNA (cytosine-5-)-methyltransferase activity CPQ89_01040 COG1070 Carbohydrate kinase CPQ89_01055 COG1195 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP CPQ89_01075 COG3010 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) CPQ89_01080 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_01080 COG2190 (PTS) system CPQ89_01080 COG1263 PTS System CPQ89_01085 COG1263 PTS System CPQ89_01085 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_01085 COG2190 (PTS) system CPQ89_01095 COG3177 Filamentation induced by cAMP protein fic CPQ89_01115 COG0446 pyridine nucleotide-disulphide oxidoreductase CPQ89_01120 COG1959 2 iron, 2 sulfur cluster binding CPQ89_01130 COG0596 Alpha beta hydrolase CPQ89_01155 COG0524 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway CPQ89_01155 COG1522 sequence-specific DNA binding CPQ89_01160 COG1957 nucleoside hydrolase CPQ89_01165 COG1972 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family CPQ89_01175 COG0135 phosphoribosylanthranilate isomerase activity CPQ89_01180 COG0524 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway CPQ89_01205 COG3850 Histidine kinase CPQ89_01205 COG5002 protein histidine kinase activity CPQ89_01240 COG0477 Major facilitator Superfamily CPQ89_01255 COG4974 Belongs to the 'phage' integrase family CPQ89_01275 COG0732 type I restriction modification DNA specificity domain CPQ89_01285 COG0110 maltose O-acetyltransferase activity CPQ89_01350 COG3973 AAA domain CPQ89_01355 COG0475 glutathione-regulated potassium exporter activity CPQ89_01355 COG0569 domain protein CPQ89_01385 COG1122 ATPase activity CPQ89_01390 COG0178 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate CPQ89_01410 COG3623 hexulose-6-phosphate isomerase CPQ89_01425 COG3037 sugar-specific permease SgaT UlaA CPQ89_01430 COG1762 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_01490 COG0012 GTP binding CPQ89_01495 COG4481 Protein conserved in bacteria CPQ89_01500 COG1475 DNA binding CPQ89_01505 COG1192 Involved in chromosome partitioning CPQ89_01525 COG1418 mRNA catabolic process CPQ89_01555 COG1108 ABC-type Mn2 Zn2 transport systems permease components CPQ89_01570 COG1131 (ABC) transporter CPQ89_01585 COG1418 mRNA catabolic process CPQ89_01600 COG1573 uracil-dna glycosylase CPQ89_01605 COG1932 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine CPQ89_01615 COG0366 Alpha amylase catalytic CPQ89_01625 COG0366 Alpha amylase catalytic CPQ89_01630 COG0366 Alpha amylase catalytic CPQ89_01635 COG1609 Transcriptional regulator CPQ89_01640 COG2182 Extracellular solute-binding protein CPQ89_01645 COG1175 transmembrane transport CPQ89_01650 COG3833 ABC-type maltose transport systems, permease component CPQ89_01675 COG1263 PTS System CPQ89_01675 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_01675 COG2190 (PTS) system CPQ89_01695 COG0515 serine threonine protein kinase CPQ89_01700 COG2274 protein secretion by the type I secretion system CPQ89_01710 COG1263 PTS System CPQ89_01710 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_01710 COG2190 (PTS) system CPQ89_01720 COG3479 Phenolic acid decarboxylase CPQ89_01750 COG3716 PTS system mannose fructose sorbose family IID component CPQ89_01755 COG3715 PTS system CPQ89_01765 COG2893 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_01765 COG3444 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_01775 COG3933 PFAM sigma-54 factor interaction domain-containing protein CPQ89_01775 COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain CPQ89_01800 COG4975 Glucose uptake CPQ89_01805 COG1869 D-ribose catabolic process CPQ89_01815 COG1609 Transcriptional regulator CPQ89_01820 COG0687 Required for the activity of the bacterial periplasmic transport system of putrescine CPQ89_01825 COG1177 transmembrane transport CPQ89_01830 COG1176 ABC-type spermidine putrescine transport system, permease component I CPQ89_01835 COG3842 ATPase activity CPQ89_01850 COG0450 alkyl hydroperoxide reductase CPQ89_01860 COG0693 protein deglycase activity CPQ89_01865 COG1182 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity CPQ89_01870 COG1279 arginine transmembrane transporter activity CPQ89_01875 COG0637 HAD-superfamily hydrolase subfamily IA, variant 3 CPQ89_01885 COG1609 Transcriptional regulator CPQ89_01895 COG2217 Heavy metal translocating P-type atpase CPQ89_01900 COG1114 Component of the transport system for branched-chain amino acids CPQ89_01905 COG1174 glycine betaine transport CPQ89_01910 COG0517 IMP dehydrogenase activity CPQ89_01910 COG1125 glycine betaine transport CPQ89_01915 COG1132 (ABC) transporter CPQ89_01920 COG1132 (ABC) transporter CPQ89_01925 COG0640 Transcriptional regulator CPQ89_01935 COG2323 membrane CPQ89_01970 COG1695 Transcriptional regulator CPQ89_01990 COG0346 lactoylglutathione lyase activity CPQ89_01995 COG0789 Transcriptional regulator CPQ89_02000 COG2814 Major facilitator Superfamily CPQ89_02035 COG0675 Transposase, IS605 OrfB family CPQ89_02050 COG1486 melibiose metabolic process CPQ89_02055 COG1263 PTS System CPQ89_02055 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_02060 COG1846 Transcriptional regulator CPQ89_02065 COG1847 R3H domain protein CPQ89_02070 COG0656 L-ascorbic acid biosynthetic process CPQ89_02075 COG3590 peptidase CPQ89_02100 COG1811 Na channel or pump CPQ89_02110 COG3022 response to hydroperoxide CPQ89_02125 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components CPQ89_02130 COG0601 transmembrane transport CPQ89_02135 COG4608 Belongs to the ABC transporter superfamily CPQ89_02145 COG1114 Component of the transport system for branched-chain amino acids CPQ89_02150 COG0833 amino acid CPQ89_02155 COG2707 UPF0756 membrane protein CPQ89_02175 COG2723 6-phospho-beta-galactosidase activity CPQ89_02180 COG0588 phosphoglycerate mutase activity CPQ89_02225 COG0845 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family CPQ89_02230 COG2274 protein secretion by the type I secretion system CPQ89_02325 COG2723 6-phospho-beta-galactosidase activity CPQ89_02330 COG1263 PTS System CPQ89_02330 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_02330 COG2190 (PTS) system CPQ89_02335 COG2188 Transcriptional regulator CPQ89_02365 COG4555 ABC transporter CPQ89_02430 COG1073 alpha beta CPQ89_02450 COG1053 succinate dehydrogenase CPQ89_02450 COG3976 FMN-binding domain protein CPQ89_02450 COG0431 NADPH-dependent FMN reductase CPQ89_02460 COG0706 membrane insertase activity CPQ89_02475 COG0593 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids CPQ89_02480 COG0592 DNA-directed DNA polymerase activity CPQ89_02485 COG2501 S4 domain CPQ89_02495 COG0187 DNA topoisomerase II activity CPQ89_02510 COG0360 Binds together with S18 to 16S ribosomal RNA CPQ89_02515 COG0629 single-stranded DNA binding CPQ89_02520 COG0238 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit CPQ89_02550 COG2826 transposase and inactivated derivatives, IS30 family CPQ89_02570 COG2274 protein secretion by the type I secretion system CPQ89_02615 COG0359 binds to the 23S rRNA CPQ89_02620 COG0583 DNA-binding transcription factor activity CPQ89_02625 COG0697 spore germination CPQ89_02645 COG0305 Participates in initiation and elongation during chromosome replication CPQ89_02650 COG0367 asparagine synthase CPQ89_02675 COG0675 Transposase, IS605 OrfB family CPQ89_02680 COG0527 aspartate kinase activity CPQ89_02690 COG0460 homoserine dehydrogenase CPQ89_02695 COG0083 homoserine kinase activity CPQ89_02730 COG0276 Catalyzes the ferrous insertion into protoporphyrin IX CPQ89_02750 COG0031 Belongs to the cysteine synthase cystathionine beta- synthase family CPQ89_02755 COG0583 DNA-binding transcription factor activity CPQ89_02785 COG0433 COG0433 Predicted ATPase CPQ89_02800 COG0738 Major facilitator superfamily CPQ89_02810 COG0082 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system CPQ89_02815 COG0128 3-phosphoshikimate 1-carboxyvinyltransferase activity CPQ89_02820 COG0703 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate CPQ89_02825 COG2252 PERMEase CPQ89_02845 COG1882 Formate acetyltransferase CPQ89_02850 COG1180 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine CPQ89_02865 COG1122 ATPase activity CPQ89_02880 COG1607 acyl-coa hydrolase CPQ89_02885 COG0474 ATPase, P-type transporting, HAD superfamily, subfamily IC CPQ89_02895 COG1972 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family CPQ89_02900 COG3759 membrane CPQ89_02930 COG0745 RESPONSE REGULATOR receiver CPQ89_02935 COG5002 protein histidine kinase activity CPQ89_02950 COG1235 May be involved in the transport of PQQ or its precursor to the periplasm CPQ89_02955 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain CPQ89_02975 COG0675 Transposase, IS605 OrfB family CPQ89_03010 COG1428 Deoxynucleoside kinase CPQ89_03030 COG0212 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family CPQ89_03035 COG0765 amino acid transport CPQ89_03045 COG1940 carbohydrate kinase activity CPQ89_03050 COG1455 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity CPQ89_03080 COG0115 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family CPQ89_03150 COG2814 Major facilitator Superfamily CPQ89_03165 COG1349 DNA-binding transcription factor activity CPQ89_03170 COG1105 Belongs to the carbohydrate kinase PfkB family CPQ89_03175 COG1762 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_03175 COG1445 protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity CPQ89_03175 COG1299 protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity CPQ89_03185 COG1113 amino acid transport CPQ89_03225 COG0562 UDP-galactopyranose mutase CPQ89_03235 COG0438 transferase activity, transferring glycosyl groups CPQ89_03250 COG0438 transferase activity, transferring glycosyl groups CPQ89_03265 COG1215 transferase activity, transferring glycosyl groups CPQ89_03270 COG0463 Glycosyl transferase, family 2 CPQ89_03290 COG1307 EDD domain protein, DegV family CPQ89_03305 COG1209 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis CPQ89_03320 COG1091 dTDP-4-dehydrorhamnose reductase activity CPQ89_03345 COG0463 Glycosyl transferase, family 2 CPQ89_03355 COG0489 protein tyrosine kinase activity CPQ89_03360 COG4464 protein tyrosine phosphatase activity CPQ89_03365 COG2148 undecaprenyl-phosphate glucose phosphotransferase activity CPQ89_03395 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain CPQ89_03400 COG1126 abc transporter atp-binding protein CPQ89_03405 COG0765 amino acid transport CPQ89_03415 COG1284 Uncharacterised 5xTM membrane BCR, YitT family COG1284 CPQ89_03420 COG1757 Na H antiporter CPQ89_03425 COG0861 Integral membrane protein TerC family CPQ89_03435 COG3118 belongs to the thioredoxin family CPQ89_03445 COG1028 Short-chain dehydrogenase reductase Sdr CPQ89_03470 COG1136 (ABC) transporter CPQ89_03470 COG0577 efflux transmembrane transporter activity CPQ89_03490 COG0640 Transcriptional regulator CPQ89_03495 COG0476 Involved in molybdopterin and thiamine biosynthesis, family 2 CPQ89_03500 COG1131 (ABC) transporter CPQ89_03515 COG0534 Mate efflux family protein CPQ89_03525 COG1122 ATPase activity CPQ89_03535 COG0310 cobalt ion transport CPQ89_03540 COG0004 ammonium transporteR CPQ89_03560 COG0804 urea catabolic process CPQ89_03570 COG0830 nickel cation binding CPQ89_03575 COG0378 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG CPQ89_03585 COG0239 Important for reducing fluoride concentration in the cell, thus reducing its toxicity CPQ89_03590 COG0239 Important for reducing fluoride concentration in the cell, thus reducing its toxicity CPQ89_03600 COG0675 Transposase, IS605 OrfB family CPQ89_03605 COG2188 Transcriptional regulator CPQ89_03635 COG0675 Transposase, IS605 OrfB family CPQ89_03640 COG3049 Linear amide C-N hydrolases, choloylglycine hydrolase family CPQ89_03650 COG4166 transmembrane transport CPQ89_03660 COG0531 amino acid CPQ89_03665 COG0194 GDP metabolic process CPQ89_03670 COG0735 belongs to the Fur family CPQ89_03690 COG0591 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family CPQ89_03695 COG0475 glutathione-regulated potassium exporter activity CPQ89_03710 COG0329 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) CPQ89_03715 COG3010 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) CPQ89_03720 COG1737 Transcriptional regulator CPQ89_03725 COG0531 amino acid CPQ89_03730 COG2262 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis CPQ89_03740 COG4166 transmembrane transport CPQ89_03745 COG0601 transmembrane transport CPQ89_03750 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components CPQ89_03755 COG0444 Belongs to the ABC transporter superfamily CPQ89_03760 COG4608 Belongs to the ABC transporter superfamily CPQ89_03765 COG2252 PERMEase CPQ89_03770 COG1455 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity CPQ89_03815 COG1511 domain protein CPQ89_03830 COG4152 abc transporter atp-binding protein CPQ89_03845 COG0168 Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA CPQ89_03870 COG1455 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity CPQ89_03875 COG1440 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity CPQ89_03880 COG1447 Phosphotransferase system cellobiose-specific component IIA CPQ89_03885 COG1940 carbohydrate kinase activity CPQ89_03890 COG2723 6-phospho-beta-galactosidase activity CPQ89_03895 COG0531 amino acid CPQ89_03910 COG0564 pseudouridine synthase activity CPQ89_03920 COG1278 Cold shock CPQ89_03925 COG2814 Major facilitator Superfamily CPQ89_03930 COG1316 TRANSCRIPTIONal CPQ89_03940 COG0730 response to heat CPQ89_03955 COG1959 2 iron, 2 sulfur cluster binding CPQ89_03960 COG0028 Belongs to the TPP enzyme family CPQ89_03965 COG3527 Alpha-acetolactate decarboxylase CPQ89_03970 COG0833 amino acid CPQ89_03980 COG0588 phosphoglycerate mutase activity CPQ89_04060 COG2071 gamma-glutamyl-gamma-aminobutyrate hydrolase activity CPQ89_04065 COG1064 alcohol dehydrogenase CPQ89_04070 COG2918 glutathione biosynthetic process CPQ89_04070 COG0189 ligase activity CPQ89_04080 COG3118 belongs to the thioredoxin family CPQ89_04085 COG0492 ferredoxin-NADP+ reductase activity CPQ89_04100 COG2271 Major facilitator Superfamily CPQ89_04110 COG0447 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) CPQ89_04120 COG0366 Alpha amylase catalytic CPQ89_04125 COG2188 Transcriptional regulator CPQ89_04130 COG1263 PTS System CPQ89_04130 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_04130 COG2190 (PTS) system CPQ89_04140 COG1609 Transcriptional regulator CPQ89_04165 COG0456 acetyltransferase CPQ89_04170 COG1846 Transcriptional regulator CPQ89_04175 COG0561 phosphatase activity CPQ89_04185 COG2217 Heavy metal translocating P-type atpase CPQ89_04200 COG1454 alcohol dehydrogenase CPQ89_04200 COG1012 belongs to the aldehyde dehydrogenase family CPQ89_04210 COG3684 Belongs to the aldolase LacD family CPQ89_04230 COG3444 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_04230 COG2893 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_04235 COG3715 PTS system CPQ89_04240 COG3716 PTS system mannose fructose sorbose family IID component CPQ89_04250 COG2222 sugar isomerase CPQ89_04255 COG1820 Belongs to the metallo-dependent hydrolases superfamily. NagA family CPQ89_04260 COG0620 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation CPQ89_04275 COG2723 6-phospho-beta-galactosidase activity CPQ89_04280 COG2190 (PTS) system CPQ89_04280 COG1264 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity CPQ89_04280 COG1263 PTS System CPQ89_04285 COG3711 transcriptional antiterminator CPQ89_04295 COG0105 UTP biosynthetic process CPQ89_04300 COG4166 transmembrane transport CPQ89_04305 COG2966 Psort location CytoplasmicMembrane, score CPQ89_04335 COG1801 Protein of unknown function DUF72 CPQ89_04340 COG0242 peptide deformylase activity CPQ89_04380 COG1197 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site CPQ89_04385 COG2244 polysaccharide biosynthetic process CPQ89_04390 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) CPQ89_04400 COG1098 S1 RNA binding domain CPQ89_04405 COG0037 tRNA processing CPQ89_04410 COG0634 Belongs to the purine pyrimidine phosphoribosyltransferase family CPQ89_04420 COG1281 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress CPQ89_04425 COG0042 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines CPQ89_04430 COG1190 Belongs to the class-II aminoacyl-tRNA synthetase family CPQ89_04470 COG3104 oligopeptide transport CPQ89_04485 COG0345 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline CPQ89_04490 COG1820 Belongs to the metallo-dependent hydrolases superfamily. NagA family CPQ89_04495 COG2188 Transcriptional regulator CPQ89_04505 COG1957 nucleoside hydrolase CPQ89_04515 COG1488 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP CPQ89_04525 COG0514 ATP-dependent DNA helicase (RecQ) CPQ89_04530 COG2183 response to ionizing radiation CPQ89_04535 COG3091 SprT-like family CPQ89_04545 COG0332 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids CPQ89_04550 COG3942 CHAP domain CPQ89_04555 COG1316 TRANSCRIPTIONal CPQ89_04565 COG0588 phosphoglycerate mutase activity CPQ89_04585 COG0120 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate CPQ89_04595 COG0756 dUTP diphosphatase activity CPQ89_04605 COG4956 integral membrane protein (PIN domain superfamily) CPQ89_04620 COG1939 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) CPQ89_04625 COG0566 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family CPQ89_04655 COG3764 Sortase (surface protein transpeptidase) CPQ89_04670 COG0250 Participates in transcription elongation, termination and antitermination CPQ89_04710 COG0435 Glutathione S-transferase CPQ89_04715 COG2898 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms CPQ89_04715 COG0392 lysyltransferase activity CPQ89_04720 COG0208 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides CPQ89_04725 COG0209 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides CPQ89_04730 COG1780 Probably involved in ribonucleotide reductase function CPQ89_04735 COG0695 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins CPQ89_04745 COG0282 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction CPQ89_04770 COG0488 (ABC) transporter CPQ89_04775 COG1376 ErfK ybiS ycfS ynhG family protein CPQ89_04780 COG1376 ErfK ybiS ycfS ynhG family protein CPQ89_04800 COG1135 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system CPQ89_04805 COG2011 ABC-type metal ion transport system permease component CPQ89_04810 COG1464 Belongs to the NlpA lipoprotein family CPQ89_04815 COG1253 flavin adenine dinucleotide binding CPQ89_04825 COG1061 Type III restriction enzyme res subunit CPQ89_04830 COG0517 IMP dehydrogenase activity CPQ89_04830 COG0516 GMP reductase activity CPQ89_04850 COG1284 Uncharacterised 5xTM membrane BCR, YitT family COG1284 CPQ89_04865 COG0334 Belongs to the Glu Leu Phe Val dehydrogenases family CPQ89_04875 COG0398 Pfam SNARE associated Golgi protein CPQ89_04895 COG2309 aminopeptidase activity CPQ89_04900 COG0381 UDP-N-acetylglucosamine 2-epimerase activity CPQ89_04910 COG0716 FMN binding CPQ89_04915 COG0024 Methionine aminopeptidase CPQ89_04920 COG1210 Utp--glucose-1-phosphate uridylyltransferase CPQ89_04925 COG3942 CHAP domain CPQ89_04925 COG1388 LysM domain CPQ89_04930 COG1295 ribonuclease BN CPQ89_04935 COG2137 regulation of response to DNA damage stimulus CPQ89_04940 COG2265 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family CPQ89_04950 COG0628 permease CPQ89_04970 COG2246 polysaccharide biosynthetic process CPQ89_04980 COG1253 flavin adenine dinucleotide binding CPQ89_05000 COG0542 response to heat CPQ89_05010 COG1925 phosphoenolpyruvate-dependent sugar phosphotransferase system CPQ89_05015 COG1080 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) CPQ89_05020 COG0438 transferase activity, transferring glycosyl groups CPQ89_05025 COG0438 transferase activity, transferring glycosyl groups CPQ89_05045 COG1368 sulfuric ester hydrolase activity CPQ89_05130 COG2855 membrane CPQ89_05135 COG0370 Transporter of a GTP-driven Fe(2 ) uptake system CPQ89_05135 COG1918 ferrous iron import across plasma membrane CPQ89_05160 COG0561 phosphatase activity CPQ89_05165 COG0692 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine CPQ89_05170 COG0280 phosphate acetyltransferase CPQ89_05175 COG0802 atpase or kinase CPQ89_05180 COG2176 DNA-directed DNA polymerase activity CPQ89_05185 COG0708 Exodeoxyribonuclease III CPQ89_05190 COG0812 UDP-N-acetylmuramate dehydrogenase activity CPQ89_05205 COG4856 YbbR-like protein CPQ89_05240 COG0448 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans CPQ89_05250 COG0058 SHG alpha-glucan phosphorylase activity CPQ89_05265 COG0573 inorganic phosphate transmembrane transporter activity CPQ89_05270 COG0581 inorganic phosphate transmembrane transporter activity CPQ89_05285 COG0704 Plays a role in the regulation of phosphate uptake CPQ89_05290 COG0191 fructose-bisphosphate aldolase activity CPQ89_05300 COG1272 protein, Hemolysin III CPQ89_05305 COG0640 Transcriptional regulator CPQ89_05350 COG4886 Leucine-rich repeat (LRR) protein CPQ89_05350 COG4932 domain protein CPQ89_05355 COG1122 ATPase activity CPQ89_05360 COG4120 Belongs to the binding-protein-dependent transport system permease family CPQ89_05380 COG1368 sulfuric ester hydrolase activity CPQ89_05385 COG4975 Glucose uptake CPQ89_05400 COG0580 Belongs to the MIP aquaporin (TC 1.A.8) family CPQ89_05410 COG0668 transmembrane transport CPQ89_05425 COG0006 proline dipeptidase activity CPQ89_05430 COG1609 Transcriptional regulator CPQ89_05450 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB CPQ89_05455 COG1459 type II secretion system CPQ89_05460 COG4537 Required for transformation and DNA binding CPQ89_05485 COG0827 DNA restriction-modification system CPQ89_05490 COG1113 amino acid transport CPQ89_05495 COG4470 Protein conserved in bacteria CPQ89_05500 COG0647 UMP catabolic process CPQ89_05510 COG0586 Pfam SNARE associated Golgi protein CPQ89_05525 COG1098 S1 RNA binding domain CPQ89_05660 COG1705 Flagellar rod assembly protein muramidase FlgJ CPQ89_05660 COG1388 LysM domain CPQ89_05670 COG1113 amino acid transport CPQ89_05675 COG2244 polysaccharide biosynthetic process CPQ89_05680 COG1187 pseudouridine synthase activity CPQ89_05685 COG0063 ADP-dependent NAD(P)H-hydrate dehydratase activity CPQ89_05690 COG0624 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls CPQ89_05725 COG0531 amino acid CPQ89_05740 COG0589 response to stress CPQ89_05770 COG0809 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) CPQ89_05775 COG0343 queuine tRNA-ribosyltransferase activity CPQ89_05780 COG1862 Preprotein translocase CPQ89_05790 COG3250 beta-galactosidase activity CPQ89_05805 COG1609 Transcriptional regulator CPQ89_05835 COG1846 Transcriptional regulator CPQ89_05855 COG0439 Biotin carboxylase CPQ89_05875 COG0364 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone CPQ89_05880 COG0389 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII CPQ89_05885 COG0618 3'(2'),5'-bisphosphate nucleotidase activity CPQ89_05890 COG0513 Belongs to the DEAD box helicase family CPQ89_05910 COG2378 regulation of single-species biofilm formation CPQ89_05975 COG0816 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA CPQ89_06000 COG3118 belongs to the thioredoxin family CPQ89_06005 COG1719 4-vinyl reductase, 4VR CPQ89_06010 COG0127 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions CPQ89_06015 COG0622 Phosphoesterase CPQ89_06055 COG0765 amino acid transport CPQ89_06060 COG1126 abc transporter atp-binding protein CPQ89_06090 COG1482 cell wall glycoprotein biosynthetic process CPQ89_06100 COG4842 Belongs to the WXG100 family CPQ89_06120 COG4499 WXG100 protein secretion system (Wss), protein YukC CPQ89_06125 COG1674 ftsk spoiiie CPQ89_06220 COG3442 glutamine amidotransferase CPQ89_06225 COG0770 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity CPQ89_06230 COG1435 thymidine kinase activity CPQ89_06240 COG2890 protein-(glutamine-N5) methyltransferase activity CPQ89_06245 COG0009 L-threonylcarbamoyladenylate synthase CPQ89_06255 COG0356 it plays a direct role in the translocation of protons across the membrane CPQ89_06285 COG0055 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits CPQ89_06300 COG0766 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine CPQ89_06305 COG1077 Cell shape determining protein MreB Mrl CPQ89_06310 COG0759 Could be involved in insertion of integral membrane proteins into the membrane CPQ89_06320 COG0772 Belongs to the SEDS family CPQ89_06325 COG1393 Belongs to the ArsC family CPQ89_06330 COG2071 gamma-glutamyl-gamma-aminobutyrate hydrolase activity CPQ89_06340 COG0719 Fe-S assembly protein CPQ89_06345 COG0520 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine CPQ89_06360 COG3279 Response regulator of the LytR AlgR family CPQ89_06405 COG0531 amino acid CPQ89_06425 COG2818 Glycosylase CPQ89_06450 COG2256 atpase related to the helicase subunit of the holliday junction resolvase CPQ89_06455 COG2918 glutathione biosynthetic process CPQ89_06455 COG0189 ligase activity CPQ89_06470 COG0726 polysaccharide deacetylase CPQ89_06480 COG1956 GAF domain-containing protein CPQ89_06485 COG4477 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization CPQ89_06490 COG1104 cysteine desulfurase activity CPQ89_06500 COG0525 valine-tRNA ligase activity CPQ89_06515 COG2003 Belongs to the UPF0758 family CPQ89_06525 COG1077 Cell shape determining protein MreB Mrl CPQ89_06540 COG0850 regulation of cytokinetic process CPQ89_06545 COG2894 cell division CPQ89_06550 COG0765 amino acid transport CPQ89_06555 COG1126 abc transporter atp-binding protein CPQ89_06565 COG1502 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol CPQ89_06595 COG0768 penicillin binding CPQ89_06630 COG1799 cell septum assembly CPQ89_06640 COG2302 S4 RNA-binding domain CPQ89_06645 COG3599 regulation of cell shape CPQ89_06665 COG0775 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively CPQ89_06670 COG1104 cysteine desulfurase activity CPQ89_06695 COG0507 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD CPQ89_06700 COG1597 lipid kinase activity CPQ89_06710 COG5503 Protein of unknown function (DUF1447) CPQ89_06730 COG4476 Belongs to the UPF0223 family CPQ89_06735 COG0483 inositol monophosphate 1-phosphatase activity CPQ89_06740 COG1217 gtp-binding protein TYPA CPQ89_06745 COG4838 Belongs to the UPF0358 family CPQ89_06750 COG0772 Belongs to the SEDS family CPQ89_06755 COG1038 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second CPQ89_06765 COG4471 UPF0298 protein CPQ89_06770 COG0742 ribosomal rna small subunit methyltransferase CPQ89_06775 COG0669 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate CPQ89_06785 COG1555 photosystem II stabilization CPQ89_06785 COG1596 polysaccharide export CPQ89_06790 COG2131 deaminase CPQ89_06800 COG1466 dna polymerase III delta subunit CPQ89_06840 COG0362 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH CPQ89_06845 COG0745 RESPONSE REGULATOR receiver CPQ89_06850 COG5002 protein histidine kinase activity CPQ89_06855 COG0706 membrane insertase activity CPQ89_06860 COG1254 Belongs to the acylphosphatase family CPQ89_06865 COG3425 synthase CPQ89_06915 COG4608 Belongs to the ABC transporter superfamily CPQ89_06920 COG0601 transmembrane transport CPQ89_06925 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components CPQ89_06940 COG2826 transposase and inactivated derivatives, IS30 family CPQ89_06945 COG0290 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins CPQ89_06960 COG2179 HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 CPQ89_06965 COG1161 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity CPQ89_06975 COG1057 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) CPQ89_06980 COG1713 HD superfamily hydrolase involved in NAD metabolism CPQ89_06985 COG0799 negative regulation of ribosome biogenesis CPQ89_06990 COG2226 methyltransferase CPQ89_07020 COG0765 amino acid transport CPQ89_07025 COG1126 abc transporter atp-binding protein CPQ89_07040 COG1835 transferase activity, transferring acyl groups other than amino-acyl groups CPQ89_07040 COG2755 lipolytic protein G-D-S-L family CPQ89_07055 COG0300 oxidoreductase activity CPQ89_07065 COG4199 Single-strand DNA-specific exonuclease, C terminal domain CPQ89_07065 COG0608 single-stranded DNA 5'-3' exodeoxyribonuclease activity CPQ89_07075 COG0569 domain protein CPQ89_07085 COG1020 D-alanine [D-alanyl carrier protein] ligase activity CPQ89_07090 COG1696 Membrane protein involved in D-alanine export CPQ89_07095 COG0236 Carrier of the growing fatty acid chain in fatty acid biosynthesis CPQ89_07100 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) CPQ89_07110 COG0768 penicillin binding CPQ89_07120 COG0457 Tetratricopeptide repeat CPQ89_07120 COG0705 Rhomboid family CPQ89_07130 COG1940 carbohydrate kinase activity CPQ89_07140 COG0330 HflC and HflK could CPQ89_07160 COG4100 CystaTHIonine beta-lyase family protein involved in aluminum resistance CPQ89_07165 COG0789 Transcriptional regulator CPQ89_07185 COG1758 RNA polymerase activity CPQ89_07190 COG0452 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine CPQ89_07195 COG1198 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA CPQ89_07205 COG0781 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons CPQ89_07205 COG0144 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA CPQ89_07210 COG0631 protein serine/threonine phosphatase activity CPQ89_07215 COG2815 serine threonine protein kinase CPQ89_07215 COG0515 serine threonine protein kinase CPQ89_07220 COG1162 GTPase activity CPQ89_07225 COG0036 Belongs to the ribulose-phosphate 3-epimerase family CPQ89_07235 COG4166 transmembrane transport CPQ89_07245 COG1302 Protein conserved in bacteria CPQ89_07250 COG1461 Dihydroxyacetone kinase CPQ89_07255 COG1200 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) CPQ89_07265 COG0236 Carrier of the growing fatty acid chain in fatty acid biosynthesis CPQ89_07275 COG1196 nuclear chromosome segregation CPQ89_07280 COG0552 protein localization to endoplasmic reticulum CPQ89_07290 COG0541 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CPQ89_07300 COG1837 Belongs to the UPF0109 family CPQ89_07305 COG0806 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes CPQ89_07315 COG1247 -acetyltransferase CPQ89_07345 COG1733 regulation of RNA biosynthetic process CPQ89_07355 COG0073 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation CPQ89_07355 COG0072 phenylalanine-tRNA ligase activity CPQ89_07370 COG1559 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation CPQ89_07380 COG0782 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus CPQ89_07410 COG2264 protein methyltransferase activity CPQ89_07415 COG1385 rRNA (uridine-N3-)-methyltransferase activity CPQ89_07425 COG0317 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance CPQ89_07440 COG0566 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family CPQ89_07450 COG0006 proline dipeptidase activity CPQ89_07455 COG0231 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase CPQ89_07460 COG1302 Protein conserved in bacteria CPQ89_07475 COG1570 exodeoxyribonuclease VII activity CPQ89_07480 COG1722 exodeoxyribonuclease VII activity CPQ89_07490 COG1189 Ribosomal RNA methyltransferase RrmJ FtsJ CPQ89_07495 COG1438 arginine binding CPQ89_07500 COG0497 DNA recombination CPQ89_07510 COG4224 UPF0291 protein CPQ89_07520 COG0204 Acyl-transferase CPQ89_07525 COG4123 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) CPQ89_07530 COG2827 Endonuclease containing a URI domain CPQ89_07535 COG1052 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family CPQ89_07550 COG2996 Protein conserved in bacteria CPQ89_07555 COG0735 belongs to the Fur family CPQ89_07580 COG1187 pseudouridine synthase activity CPQ89_07585 COG3601 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins CPQ89_07590 COG1914 H( )-stimulated, divalent metal cation uptake system CPQ89_07595 COG4955 Helix-turn-helix domain CPQ89_07600 COG0514 ATP-dependent DNA helicase (RecQ) CPQ89_07615 COG0539 negative regulation of cytoplasmic translation CPQ89_07635 COG0745 RESPONSE REGULATOR receiver CPQ89_07640 COG2205 protein histidine kinase activity CPQ89_07645 COG1136 (ABC) transporter CPQ89_07670 COG0393 Putative heavy-metal-binding CPQ89_07685 COG1942 4-Oxalocrotonate Tautomerase CPQ89_07690 COG0561 phosphatase activity CPQ89_07695 COG1073 alpha beta CPQ89_07700 COG2151 metal-sulfur cluster biosynthetic enzyme CPQ89_07710 COG3270 Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA CPQ89_07710 COG0144 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA CPQ89_07730 COG1304 FMN binding CPQ89_07750 COG0847 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease CPQ89_07750 COG1199 ATP-dependent helicase activity CPQ89_07760 COG0436 Aminotransferase CPQ89_07775 COG0177 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate CPQ89_07785 COG0744 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors CPQ89_07835 COG0116 Belongs to the methyltransferase superfamily CPQ89_07840 COG0328 RNA-DNA hybrid ribonuclease activity CPQ89_07860 COG0564 pseudouridine synthase activity CPQ89_07870 COG2233 PERMEase CPQ89_07885 COG0505 Belongs to the CarA family CPQ89_07895 COG0167 dihydroorotate dehydrogenase activity CPQ89_07910 COG1316 TRANSCRIPTIONal CPQ89_07915 COG0583 DNA-binding transcription factor activity CPQ89_07920 COG1227 inorganic diphosphatase activity CPQ89_07930 COG1268 BioY protein CPQ89_07935 COG0436 Aminotransferase CPQ89_07985 COG0187 DNA topoisomerase II activity CPQ89_07995 COG1293 RNA-binding protein homologous to eukaryotic snRNP CPQ89_08000 COG1307 EDD domain protein, DegV family CPQ89_08060 COG5405 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery CPQ89_08065 COG4974 Belongs to the 'phage' integrase family CPQ89_08075 COG0550 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone CPQ89_08080 COG0758 DNA mediated transformation CPQ89_08095 COG0681 Belongs to the peptidase S26 family CPQ89_08100 COG0793 Belongs to the peptidase S41A family CPQ89_08100 COG3409 Peptidoglycan-binding domain 1 protein CPQ89_08105 COG4479 Belongs to the UPF0346 family CPQ89_08115 COG2755 lipolytic protein G-D-S-L family CPQ89_08125 COG0262 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis CPQ89_08135 COG0488 (ABC) transporter CPQ89_08145 COG1284 Uncharacterised 5xTM membrane BCR, YitT family COG1284 CPQ89_08155 COG0457 Tetratricopeptide repeat CPQ89_08160 COG0136 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate CPQ89_08165 COG0289 4-hydroxy-tetrahydrodipicolinate reductase CPQ89_08170 COG0329 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) CPQ89_08175 COG1473 amidohydrolase CPQ89_08180 COG2171 N-acyltransferase activity CPQ89_08185 COG0019 diaminopimelate decarboxylase activity CPQ89_08205 COG0587 DNA-directed DNA polymerase activity CPQ89_08215 COG0542 response to heat CPQ89_08225 COG0327 Belongs to the GTP cyclohydrolase I type 2 NIF3 family CPQ89_08230 COG2384 SAM-dependent methyltransferase CPQ89_08315 COG0568 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released CPQ89_08320 COG0358 DNA primase activity CPQ89_08355 COG0679 Auxin Efflux Carrier CPQ89_08380 COG0818 Recycling of diacylglycerol produced during the turnover of membrane phospholipid CPQ89_08390 COG1702 phosphate starvation-inducible protein PhoH CPQ89_08395 COG1610 YqeY-like protein CPQ89_08410 COG0648 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin CPQ89_08415 COG1216 Glycosyl transferase, family 2 CPQ89_08425 COG0438 transferase activity, transferring glycosyl groups CPQ89_08450 COG2077 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides CPQ89_08475 COG0813 purine-nucleoside phosphorylase activity CPQ89_08480 COG1015 Phosphotransfer between the C1 and C5 carbon atoms of pentose CPQ89_08560 COG4570 Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC CPQ89_08640 COG1396 sequence-specific DNA binding CPQ89_08690 COG0484 heat shock protein binding CPQ89_08695 COG0443 Heat shock 70 kDa protein CPQ89_08700 COG0576 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ CPQ89_08710 COG0196 riboflavin kinase activity CPQ89_08735 COG2740 Nucleic-acid-binding protein implicated in transcription termination CPQ89_08740 COG0195 Participates in both transcription termination and antitermination CPQ89_08775 COG0750 zinc metalloprotease CPQ89_08785 COG0020 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids CPQ89_08800 COG4991 sh3 domain protein CPQ89_08800 COG3103 Sh3 type 3 domain protein CPQ89_08800 COG0860 N-Acetylmuramoyl-L-alanine amidase CPQ89_08805 COG0211 Belongs to the bacterial ribosomal protein bL27 family CPQ89_08830 COG1502 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol CPQ89_08830 COG1112 Superfamily I DNA and RNA helicases and helicase subunits CPQ89_08840 COG1598 PFAM Uncharacterised protein family UPF0150 CPQ89_08855 COG0610 Subunit R is required for both nuclease and ATPase activities, but not for modification CPQ89_08890 COG4974 Belongs to the 'phage' integrase family CPQ89_08935 COG0783 Belongs to the Dps family CPQ89_08980 COG0624 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls CPQ89_08985 COG1959 2 iron, 2 sulfur cluster binding CPQ89_09100 COG1484 DNA-dependent DNA replication CPQ89_09115 COG0237 dephospho-CoA kinase activity CPQ89_09125 COG0749 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity CPQ89_09125 COG0258 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity CPQ89_09130 COG0732 type I restriction modification DNA specificity domain CPQ89_09145 COG4974 Belongs to the 'phage' integrase family CPQ89_09155 COG0732 type I restriction modification DNA specificity domain CPQ89_09160 COG0286 site-specific DNA-methyltransferase (adenine-specific) activity CPQ89_09165 COG4096 Type I site-specific restriction-modification system, R (Restriction) subunit and related CPQ89_09180 COG0670 Belongs to the BI1 family CPQ89_09190 COG0584 glycerophosphoryl diester phosphodiesterase CPQ89_09215 COG1674 ftsk spoiiie CPQ89_09220 COG0073 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation CPQ89_09225 COG0526 COG0526, thiol-disulfide isomerase and thioredoxins CPQ89_09235 COG0510 thiamine kinase activity CPQ89_09240 COG4473 ABC transporter CPQ89_09245 COG1131 (ABC) transporter CPQ89_09255 COG0537 adenosine 5'-monophosphoramidase activity CPQ89_09280 COG3481 metal-dependent phosphohydrolase, HD sub domain CPQ89_09290 COG0744 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors CPQ89_09295 COG1438 arginine binding CPQ89_09320 COG0583 DNA-binding transcription factor activity CPQ89_09360 COG1828 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL CPQ89_09365 COG0152 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity CPQ89_09370 COG0015 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily CPQ89_09375 COG0026 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) CPQ89_09380 COG0041 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) CPQ89_09390 COG1428 Deoxynucleoside kinase CPQ89_09400 COG0468 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage CPQ89_09405 COG0558 Belongs to the CDP-alcohol phosphatidyltransferase class-I family CPQ89_09410 COG1426 Protein conserved in bacteria CPQ89_09415 COG1028 Short-chain dehydrogenase reductase Sdr CPQ89_09420 COG0612 Peptidase, M16 CPQ89_09425 COG0612 Peptidase, M16 CPQ89_09430 COG1674 ftsk spoiiie CPQ89_09450 COG0219 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide CPQ89_09475 COG2706 6-phosphogluconolactonase activity CPQ89_09480 COG3142 Participates in the control of copper homeostasis CPQ89_09490 COG2239 Acts as a magnesium transporter CPQ89_09495 COG0564 pseudouridine synthase activity CPQ89_09505 COG2357 RelA SpoT domain protein CPQ89_09525 COG4862 establishment of competence for transformation CPQ89_09530 COG1393 Belongs to the ArsC family CPQ89_09540 COG1328 CTP reductase activity CPQ89_09545 COG4475 Protein of unknown function (DUF436) CPQ89_09555 COG0557 exoribonuclease II activity CPQ89_09560 COG1314 P-P-bond-hydrolysis-driven protein transmembrane transporter activity CPQ89_09565 COG0038 chloride channel CPQ89_09595 COG1508 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding CPQ89_09615 COG3942 CHAP domain CPQ89_09615 COG1388 LysM domain CPQ89_09780 COG3723 Recombinational DNA repair protein, rece pathway CPQ89_09875 COG1760 l-serine dehydratase CPQ89_09880 COG1760 l-serine dehydratase CPQ89_09890 COG0178 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate CPQ89_09895 COG0556 nucleotide-excision repair CPQ89_09900 COG1109 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate CPQ89_09940 COG0492 ferredoxin-NADP+ reductase activity CPQ89_09945 COG0682 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins CPQ89_09950 COG1493 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion CPQ89_09955 COG1950 PFAM Membrane protein of CPQ89_09965 COG5002 protein histidine kinase activity CPQ89_09970 COG0745 RESPONSE REGULATOR receiver CPQ89_09980 COG2177 Part of the ABC transporter FtsEX involved in CPQ89_09985 COG2884 Cell division ATP-binding protein ftsE CPQ89_10005 COG1040 competence protein CPQ89_10010 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) CPQ89_10015 COG1739 Uncharacterized protein family UPF0029 CPQ89_10020 COG0472 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan CPQ89_10025 COG0531 amino acid CPQ89_10050 COG0488 (ABC) transporter CPQ89_10065 COG1214 PFAM Peptidase M22, glycoprotease CPQ89_10090 COG0470 DNA polymerase III CPQ89_10095 COG3870 Protein conserved in bacteria CPQ89_10120 COG2812 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity CPQ89_10130 COG0590 tRNA wobble adenosine to inosine editing CPQ89_10135 COG2813 Specifically methylates the guanine in position CPQ89_10160 COG2826 transposase and inactivated derivatives, IS30 family CPQ89_10190 COG0673 inositol 2-dehydrogenase activity CPQ89_10200 COG2197 response regulator CPQ89_10215 COG1131 (ABC) transporter CPQ89_10250 COG5646 InterPro IPR014922 CPQ89_10265 COG0431 NADPH-dependent FMN reductase CPQ89_10265 COG3976 FMN-binding domain protein CPQ89_10265 COG1053 succinate dehydrogenase CPQ89_10280 COG2814 Major facilitator Superfamily CPQ89_10310 COG1476 TRANSCRIPTIONal CPQ89_10365 COG2211 Major facilitator Superfamily CPQ89_10375 COG0609 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily CPQ89_10380 COG0609 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily CPQ89_10390 COG1120 ATPase activity CPQ89_10405 COG2265 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family CPQ89_10415 COG2256 atpase related to the helicase subunit of the holliday junction resolvase CPQ89_10420 COG1597 lipid kinase activity CPQ89_10455 COG0026 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) CPQ89_10460 COG2233 PERMEase CPQ89_10470 COG1705 Flagellar rod assembly protein muramidase FlgJ CPQ89_10475 COG4684 Psort location CytoplasmicMembrane, score CPQ89_10485 COG0281 malic enzyme CPQ89_10490 COG0583 DNA-binding transcription factor activity CPQ89_10505 COG2261 transglycosylase associated protein CPQ89_10515 COG1302 Protein conserved in bacteria CPQ89_10535 COG1396 sequence-specific DNA binding CPQ89_10565 COG1158 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template CPQ89_10570 COG0766 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine CPQ89_10590 COG1078 dGTPase activity CPQ89_10600 COG1179 involved in molybdopterin and THIamine biosynthesis family 1 CPQ89_10635 COG0394 Belongs to the low molecular weight phosphotyrosine protein phosphatase family CPQ89_10640 COG0488 (ABC) transporter CPQ89_10655 COG0462 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) CPQ89_10665 COG0503 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis CPQ89_10675 COG0165 Argininosuccinate lyase CPQ89_10695 COG0095 Lipoate-protein ligase CPQ89_10720 COG2814 Major facilitator Superfamily CPQ89_10725 COG4466 Protein conserved in bacteria CPQ89_10740 COG0084 hydrolase, TatD family' CPQ89_10745 COG0073 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation CPQ89_10745 COG0143 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation CPQ89_10750 COG1267 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) CPQ89_10765 COG3583 domain protein CPQ89_10775 COG0248 Ppx GppA phosphatase CPQ89_10785 COG0366 Alpha amylase catalytic CPQ89_10790 COG0395 ABC-type sugar transport system, permease component CPQ89_10795 COG1175 transmembrane transport CPQ89_10800 COG1653 transport CPQ89_10810 COG0366 Alpha amylase catalytic CPQ89_10815 COG3842 ATPase activity CPQ89_10820 COG2508 Transcriptional regulator CPQ89_10830 COG0225 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine CPQ89_10835 COG0477 Major facilitator Superfamily CPQ89_10835 COG0477 Major facilitator Superfamily CPQ89_10840 COG1136 (ABC) transporter CPQ89_10840 COG0577 efflux transmembrane transporter activity CPQ89_10845 COG1136 (ABC) transporter CPQ89_10845 COG0577 efflux transmembrane transporter activity CPQ89_10855 COG3973 AAA domain CPQ89_10930 COG1988 membrane-bound metal-dependent CPQ89_10935 COG0419 ATPase involved in DNA repair CPQ89_10940 COG0420 3'-5' exonuclease activity CPQ89_10945 COG0110 maltose O-acetyltransferase activity CPQ89_10965 COG0736 holo-[acyl-carrier-protein] synthase activity CPQ89_10975 COG1139 Iron-sulfur cluster binding protein CPQ89_10980 COG0247 lactate metabolic process CPQ89_10985 COG1252 NADH dehydrogenase CPQ89_11000 COG4987 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC CPQ89_11005 COG4988 ABC transporter CPQ89_11010 COG1294 oxidase, subunit CPQ89_11015 COG1271 oxidase subunit CPQ89_11045 COG0770 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity CPQ89_11055 COG1704 LemA family CPQ89_11080 COG1132 (ABC) transporter CPQ89_11105 COG1053 succinate dehydrogenase CPQ89_11125 COG3682 Transcriptional regulator CPQ89_11130 COG1968 undecaprenyl-diphosphatase activity CPQ89_11135 COG0586 Pfam SNARE associated Golgi protein CPQ89_11140 COG2230 cyclopropane-fatty-acyl-phospholipid synthase CPQ89_11155 COG0551 DNA topoisomerase type I activity CPQ89_11155 COG0550 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone