locus-tag	class	description
FLP23_00020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLP23_00030	COG0028	Belongs to the TPP enzyme family
FLP23_00035	COG0129	dihydroxy-acid dehydratase activity
FLP23_00050	COG1082	Xylose isomerase domain protein TIM barrel
FLP23_00060	COG2409	Drug exporters of the RND superfamily
FLP23_00075	COG2188	Transcriptional regulator
FLP23_00085	COG1012	belongs to the aldehyde dehydrogenase family
FLP23_00090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FLP23_00100	COG0833	amino acid
FLP23_00170	COG0653	protein targeting
FLP23_00175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLP23_00180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLP23_00185	COG5401	PFAM Sporulation and spore germination
FLP23_00190	COG5002	protein histidine kinase activity
FLP23_00190	COG5000	phosphorelay sensor kinase activity
FLP23_00195	COG0745	RESPONSE REGULATOR receiver
FLP23_00215	COG0714	Associated with various cellular activities
FLP23_00225	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FLP23_00230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FLP23_00295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FLP23_00300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLP23_00330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FLP23_00345	COG1482	cell wall glycoprotein biosynthetic process
FLP23_00350	COG1960	acyl-CoA dehydrogenase activity
FLP23_00380	COG2755	lipolytic protein G-D-S-L family
FLP23_00380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FLP23_00420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FLP23_00465	COG0463	Glycosyl transferase, family 2
FLP23_00490	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FLP23_00495	COG1088	dTDP-glucose 4,6-dehydratase activity
FLP23_00505	COG0438	transferase activity, transferring glycosyl groups
FLP23_00510	COG0438	transferase activity, transferring glycosyl groups
FLP23_00510	COG1216	Glycosyl transferase, family 2
FLP23_00515	COG1316	TRANSCRIPTIONal
FLP23_00520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLP23_00525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLP23_00545	COG0463	Glycosyl transferase, family 2
FLP23_00550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLP23_00575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLP23_00580	COG0424	maF-like protein
FLP23_00585	COG4770	biotin carboxylase activity
FLP23_00590	COG0463	Glycosyl transferase, family 2
FLP23_00590	COG1216	Glycosyl transferase, family 2
FLP23_00600	COG1216	Glycosyl transferase, family 2
FLP23_00615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLP23_00630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FLP23_00665	COG1744	ABC transporter substrate-binding protein PnrA-like
FLP23_00675	COG2009	succinate dehydrogenase
FLP23_00710	COG0180	Tryptophanyl-tRNA synthetase
FLP23_00730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLP23_00730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLP23_00735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FLP23_00740	COG0477	Major facilitator Superfamily
FLP23_00760	COG1132	(ABC) transporter
FLP23_00765	COG3415	Transposase
FLP23_00765	COG2801	Transposase and inactivated derivatives
FLP23_00770	COG3250	beta-galactosidase activity
FLP23_00775	COG0395	ABC-type sugar transport system, permease component
FLP23_00780	COG4209	transmembrane transport
FLP23_00805	COG1335	isochorismatase
FLP23_00810	COG2027	D-alanyl-D-alanine carboxypeptidase
FLP23_00835	COG0470	DNA polymerase III
FLP23_00840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLP23_00845	COG1754	DNA topoisomerase type I activity
FLP23_00845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLP23_00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLP23_00905	COG1408	metallophosphoesterase
FLP23_00915	COG1435	thymidine kinase activity
FLP23_00930	COG0488	(ABC) transporter
FLP23_00935	COG0579	oxidoreductase
FLP23_00965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLP23_00995	COG1131	(ABC) transporter
FLP23_01020	COG2814	Major facilitator Superfamily
FLP23_01040	COG1879	ABC-type sugar transport system periplasmic component
FLP23_01045	COG1129	ABC transporter
FLP23_01050	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLP23_01065	COG1653	transport
FLP23_01070	COG1175	transmembrane transport
FLP23_01075	COG0395	ABC-type sugar transport system, permease component
FLP23_01090	COG3693	PFAM glycoside hydrolase, family 10
FLP23_01100	COG2115	Belongs to the xylose isomerase family
FLP23_01105	COG1070	Carbohydrate kinase
FLP23_01120	COG0531	amino acid
FLP23_01135	COG1132	(ABC) transporter
FLP23_01140	COG0395	ABC-type sugar transport system, permease component
FLP23_01145	COG1175	transmembrane transport
FLP23_01150	COG1653	transport
FLP23_01155	COG0222	ribosome binding
FLP23_01160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLP23_01170	COG2205	protein histidine kinase activity
FLP23_01175	COG0745	RESPONSE REGULATOR receiver
FLP23_01185	COG1063	alcohol dehydrogenase
FLP23_01200	COG0081	regulation of translation
FLP23_01205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLP23_01210	COG1280	lysine exporter protein (LysE YggA)
FLP23_01260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLP23_01290	COG2197	response regulator
FLP23_01315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLP23_01325	COG2030	dehydratase
FLP23_01335	COG2197	response regulator
FLP23_01340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLP23_01385	COG0366	Alpha amylase catalytic
FLP23_01390	COG0366	Alpha amylase catalytic
FLP23_01395	COG0739	heme binding
FLP23_01410	COG3415	Transposase
FLP23_01410	COG2801	Transposase and inactivated derivatives
FLP23_01475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FLP23_01480	COG0582	viral genome integration into host DNA
FLP23_01500	COG1666	GTP binding
FLP23_01530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLP23_01545	COG0142	geranyltranstransferase activity
FLP23_01550	COG2226	methyltransferase
FLP23_01555	COG1169	isochorismate synthase
FLP23_01560	COG2326	polyphosphate kinase activity
FLP23_01565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FLP23_01590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FLP23_01605	COG4948	Mandelate Racemase Muconate Lactonizing
FLP23_01615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLP23_01620	COG1333	cytochrome c biogenesis protein
FLP23_01625	COG0785	Cytochrome C biogenesis protein
FLP23_01630	COG3118	belongs to the thioredoxin family
FLP23_01635	COG0406	alpha-ribazole phosphatase activity
FLP23_01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_01645	COG1733	regulation of RNA biosynthetic process
FLP23_01655	COG0017	Asparaginyl-tRNA synthetase
FLP23_01685	COG0560	Phosphoserine phosphatase
FLP23_01710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLP23_01715	COG0569	domain protein
FLP23_01735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLP23_01750	COG1846	Transcriptional regulator
FLP23_01755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLP23_01760	COG2313	pseudouridylate synthase activity
FLP23_01765	COG0277	FAD linked oxidase domain protein
FLP23_01770	COG0318	PFAM AMP-dependent synthetase and ligase
FLP23_01770	COG0204	Acyl-transferase
FLP23_01775	COG0300	oxidoreductase activity
FLP23_01805	COG1309	transcriptional regulator
FLP23_01810	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_01830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLP23_01855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLP23_01875	COG3415	Transposase
FLP23_01875	COG2801	Transposase and inactivated derivatives
FLP23_01995	COG2932	Transcriptional regulator
FLP23_02010	COG1309	transcriptional regulator
FLP23_02025	COG0310	cobalt ion transport
FLP23_02055	COG0831	urea catabolic process
FLP23_02060	COG0832	Belongs to the urease beta subunit family
FLP23_02075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FLP23_02080	COG0829	nickel cation binding
FLP23_02090	COG0745	RESPONSE REGULATOR receiver
FLP23_02110	COG0667	Aldo Keto reductase
FLP23_02120	COG2011	ABC-type metal ion transport system permease component
FLP23_02130	COG1464	Belongs to the NlpA lipoprotein family
FLP23_02150	COG0701	Predicted permease
FLP23_02155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLP23_02180	COG3833	ABC-type maltose transport systems, permease component
FLP23_02185	COG1175	transmembrane transport
FLP23_02195	COG1609	Transcriptional regulator
FLP23_02200	COG0383	alpha-mannosidase activity
FLP23_02205	COG2211	Major facilitator Superfamily
FLP23_02245	COG1316	TRANSCRIPTIONal
FLP23_02255	COG1316	TRANSCRIPTIONal
FLP23_02265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLP23_02275	COG0077	Prephenate dehydratase
FLP23_02285	COG1876	peptidase activity
FLP23_02300	COG0395	ABC-type sugar transport system, permease component
FLP23_02325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FLP23_02330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLP23_02335	COG0095	Lipoate-protein ligase
FLP23_02345	COG2814	Major facilitator Superfamily
FLP23_02365	COG1609	Transcriptional regulator
FLP23_02375	COG4948	Mandelate Racemase Muconate Lactonizing
FLP23_02400	COG0395	ABC-type sugar transport system, permease component
FLP23_02405	COG4209	transmembrane transport
FLP23_02410	COG3458	cephalosporin-C deacetylase activity
FLP23_02415	COG0246	Mannitol dehydrogenase
FLP23_02420	COG1305	Transglutaminase-like
FLP23_02460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLP23_02465	COG1834	amidinotransferase
FLP23_02480	COG1725	Transcriptional regulator
FLP23_02485	COG0656	L-ascorbic acid biosynthetic process
FLP23_02505	COG4585	Histidine kinase
FLP23_02510	COG2197	response regulator
FLP23_02515	COG4152	abc transporter atp-binding protein
FLP23_02520	COG1668	transmembrane transport
FLP23_02530	COG0318	PFAM AMP-dependent synthetase and ligase
FLP23_02535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_02540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLP23_02545	COG0542	response to heat
FLP23_02560	COG3550	peptidyl-serine autophosphorylation
FLP23_02570	COG0789	Transcriptional regulator
FLP23_02575	COG0484	heat shock protein binding
FLP23_02580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLP23_02585	COG0443	Heat shock 70 kDa protein
FLP23_02605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FLP23_02610	COG0717	Belongs to the dCTP deaminase family
FLP23_02630	COG5398	heme oxygenase
FLP23_02635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLP23_02645	COG3336	cytochrome c oxidase
FLP23_02650	COG0776	regulation of translation
FLP23_02655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLP23_02665	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLP23_02685	COG1121	(ABC) transporter
FLP23_02690	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP23_02695	COG0022	dehydrogenase e1 component
FLP23_02705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLP23_02710	COG1950	PFAM Membrane protein of
FLP23_02725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLP23_02730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLP23_02745	COG0305	Participates in initiation and elongation during chromosome replication
FLP23_02750	COG0359	binds to the 23S rRNA
FLP23_02755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLP23_02765	COG0360	Binds together with S18 to 16S ribosomal RNA
FLP23_02770	COG0617	tRNA 3'-terminal CCA addition
FLP23_02780	COG0728	peptidoglycan biosynthetic process
FLP23_02790	COG3118	belongs to the thioredoxin family
FLP23_02795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLP23_02800	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLP23_02810	COG1192	Involved in chromosome partitioning
FLP23_02820	COG0357	Ribosomal RNA small subunit methyltransferase G
FLP23_02830	COG0706	membrane insertase activity
FLP23_02835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FLP23_02840	COG0594	ribonuclease P activity
FLP23_02845	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FLP23_02850	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLP23_02855	COG0592	DNA-directed DNA polymerase activity
FLP23_02860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FLP23_02865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLP23_02870	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FLP23_02875	COG0187	DNA topoisomerase II activity
FLP23_02880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLP23_02925	COG0705	Rhomboid family
FLP23_02945	COG0515	serine threonine protein kinase
FLP23_02945	COG2815	serine threonine protein kinase
FLP23_02955	COG0768	penicillin binding
FLP23_02975	COG1716	ATPase activity
FLP23_02985	COG3973	AAA domain
FLP23_02990	COG0569	domain protein
FLP23_02990	COG0189	ligase activity
FLP23_02995	COG4067	protein conserved in archaea
FLP23_02995	COG0189	ligase activity
FLP23_03000	COG0490	domain, Protein
FLP23_03000	COG0471	metal ion transport
FLP23_03025	COG1755	Isoprenylcysteine carboxyl methyltransferase
FLP23_03040	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FLP23_03045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FLP23_03065	COG0738	Major facilitator superfamily
FLP23_03080	COG3590	peptidase
FLP23_03095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FLP23_03100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLP23_03135	COG0181	hydroxymethylbilane synthase activity
FLP23_03150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLP23_03160	COG0604	alcohol dehydrogenase
FLP23_03200	COG2267	carboxylic ester hydrolase activity
FLP23_03205	COG1113	amino acid transport
FLP23_03255	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FLP23_03280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FLP23_03295	COG1605	Chorismate mutase
FLP23_03295	COG0287	Prephenate dehydrogenase
FLP23_03305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLP23_03345	COG0047	phosphoribosylformylglycinamidine synthase activity
FLP23_03355	COG0572	uridine kinase
FLP23_03365	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FLP23_03370	COG3639	organic phosphonate transmembrane transporter activity
FLP23_03380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLP23_03385	COG1063	alcohol dehydrogenase
FLP23_03395	COG2514	catechol 2,3-dioxygenase activity
FLP23_03400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLP23_03405	COG0151	Belongs to the GarS family
FLP23_03430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FLP23_03435	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_03450	COG0531	amino acid
FLP23_03475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLP23_03480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLP23_03485	COG0513	Belongs to the DEAD box helicase family
FLP23_03490	COG0514	ATP-dependent DNA helicase (RecQ)
FLP23_03505	COG0204	Acyl-transferase
FLP23_03505	COG0318	PFAM AMP-dependent synthetase and ligase
FLP23_03525	COG0598	Magnesium transport protein CorA
FLP23_03540	COG0640	Transcriptional regulator
FLP23_03545	COG3311	Transcriptional regulator
FLP23_03570	COG0741	lytic transglycosylase activity
FLP23_03570	COG1196	nuclear chromosome segregation
FLP23_03570	COG0739	heme binding
FLP23_03580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FLP23_03585	COG0037	tRNA processing
FLP23_03595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLP23_03600	COG0302	gtp cyclohydrolase
FLP23_03610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLP23_03615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLP23_03635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLP23_03640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLP23_03660	COG3655	Transcriptional regulator
FLP23_03675	COG0542	response to heat
FLP23_03690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FLP23_03710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLP23_03735	COG0596	Alpha beta hydrolase
FLP23_03750	COG2813	Specifically methylates the guanine in position
FLP23_03755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_03770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLP23_03775	COG1201	RNA secondary structure unwinding
FLP23_03800	COG0513	Belongs to the DEAD box helicase family
FLP23_03825	COG0085	RNA polymerase activity
FLP23_03830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLP23_03860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLP23_03895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FLP23_03900	COG0849	cell division
FLP23_03920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLP23_03925	COG0049	tRNA binding
FLP23_03930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLP23_03935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLP23_03990	COG0051	transcription antitermination factor activity, RNA binding
FLP23_03995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLP23_04000	COG0088	Forms part of the polypeptide exit tunnel
FLP23_04005	COG0089	rRNA binding
FLP23_04010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLP23_04015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLP23_04020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLP23_04025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLP23_04030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLP23_04035	COG0255	Belongs to the universal ribosomal protein uL29 family
FLP23_04040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLP23_04045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLP23_04050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FLP23_04055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLP23_04060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLP23_04065	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLP23_04070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLP23_04075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLP23_04080	COG1841	ribosomal large subunit assembly
FLP23_04085	COG0200	Binds to the 23S rRNA
FLP23_04095	COG0563	adenylate kinase activity
FLP23_04100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLP23_04105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLP23_04110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLP23_04115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLP23_04120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLP23_04125	COG0202	RNA polymerase activity
FLP23_04130	COG0203	ribosomal protein L17
FLP23_04135	COG0101	tRNA pseudouridine synthase activity
FLP23_04140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLP23_04145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FLP23_04150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLP23_04160	COG1072	(Pantothenic acid kinase))
FLP23_04165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLP23_04170	COG0736	holo-[acyl-carrier-protein] synthase activity
FLP23_04175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLP23_04180	COG0802	atpase or kinase
FLP23_04190	COG0456	acetyltransferase
FLP23_04195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLP23_04215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLP23_04245	COG0411	ABC transporter
FLP23_04250	COG0410	ABC transporter
FLP23_04265	COG0516	GMP reductase activity
FLP23_04270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLP23_04280	COG0475	glutathione-regulated potassium exporter activity
FLP23_04295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLP23_04295	COG0519	Catalyzes the synthesis of GMP from XMP
FLP23_04315	COG0584	glycerophosphoryl diester phosphodiesterase
FLP23_04335	COG0045	succinate-CoA ligase (ADP-forming) activity
FLP23_04360	COG0138	bifunctional purine biosynthesis protein purh
FLP23_04365	COG2252	PERMEase
FLP23_04405	COG0039	L-malate dehydrogenase activity
FLP23_04425	COG1477	protein flavinylation
FLP23_04435	COG1940	carbohydrate kinase activity
FLP23_04445	COG1175	transmembrane transport
FLP23_04460	COG1940	carbohydrate kinase activity
FLP23_04465	COG0363	glucosamine-6-phosphate deaminase activity
FLP23_04470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLP23_04480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLP23_04485	COG0788	formyltetrahydrofolate deformylase activity
FLP23_04490	COG2814	Major facilitator Superfamily
FLP23_04495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLP23_04500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLP23_04510	COG2017	converts alpha-aldose to the beta-anomer
FLP23_04530	COG2890	protein-(glutamine-N5) methyltransferase activity
FLP23_04555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLP23_04580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FLP23_04585	COG0745	RESPONSE REGULATOR receiver
FLP23_04595	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FLP23_04600	COG0354	folic acid binding
FLP23_04620	COG0588	phosphoglycerate mutase activity
FLP23_04640	COG5002	protein histidine kinase activity
FLP23_04655	COG1329	Transcriptional regulator
FLP23_04660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FLP23_04660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FLP23_04670	COG0215	cysteine-tRNA ligase activity
FLP23_04680	COG2409	Drug exporters of the RND superfamily
FLP23_04690	COG3842	ATPase activity
FLP23_04710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLP23_04730	COG1278	Cold shock
FLP23_04735	COG1470	cell adhesion involved in biofilm formation
FLP23_04740	COG0459	protein refolding
FLP23_04750	COG5002	protein histidine kinase activity
FLP23_04750	COG5000	phosphorelay sensor kinase activity
FLP23_04755	COG0745	RESPONSE REGULATOR receiver
FLP23_04785	COG1061	Type III restriction enzyme res subunit
FLP23_04800	COG1278	Cold shock
FLP23_04815	COG3415	Transposase
FLP23_04815	COG2801	Transposase and inactivated derivatives
FLP23_04820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLP23_04825	COG1321	iron dependent repressor
FLP23_04855	COG0454	-acetyltransferase
FLP23_04870	COG1970	mechanosensitive ion channel activity
FLP23_04880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLP23_04885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLP23_04905	COG2801	Transposase and inactivated derivatives
FLP23_04905	COG3415	Transposase
FLP23_04920	COG2160	L-arabinose isomerase activity
FLP23_04950	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_04955	COG2186	Transcriptional regulator
FLP23_05005	COG1846	Transcriptional regulator
FLP23_05015	COG4721	ABC-type cobalt transport system, permease component
FLP23_05030	COG1122	ATPase activity
FLP23_05035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLP23_05040	COG2375	cellular response to nickel ion
FLP23_05065	COG1309	transcriptional regulator
FLP23_05085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLP23_05115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLP23_05135	COG1132	(ABC) transporter
FLP23_05160	COG0667	Aldo Keto reductase
FLP23_05175	COG0601	transmembrane transport
FLP23_05180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP23_05190	COG1132	(ABC) transporter
FLP23_05195	COG1132	(ABC) transporter
FLP23_05200	COG0667	Aldo Keto reductase
FLP23_05210	COG1643	Atp-dependent helicase
FLP23_05225	COG1131	(ABC) transporter
FLP23_05240	COG3415	Transposase
FLP23_05240	COG2801	Transposase and inactivated derivatives
FLP23_05250	COG1331	Highly conserved protein containing a thioredoxin domain
FLP23_05270	COG1832	CoA-binding protein
FLP23_05295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLP23_05300	COG0084	hydrolase, TatD family'
FLP23_05305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLP23_05310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLP23_05365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLP23_05375	COG0659	secondary active sulfate transmembrane transporter activity
FLP23_05385	COG0488	(ABC) transporter
FLP23_05425	COG0473	3-isopropylmalate dehydrogenase activity
FLP23_05460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLP23_05465	COG1215	transferase activity, transferring glycosyl groups
FLP23_05490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLP23_05500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLP23_05505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLP23_05540	COG1045	serine acetyltransferase
FLP23_05565	COG1846	Transcriptional regulator
FLP23_05580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLP23_05585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLP23_05610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FLP23_05615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLP23_05620	COG3265	gluconokinase activity
FLP23_05630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLP23_05635	COG0193	aminoacyl-tRNA hydrolase activity
FLP23_05645	COG0800	Aldolase
FLP23_05685	COG0477	Major facilitator Superfamily
FLP23_05700	COG5006	permease, DMT superfamily
FLP23_05710	COG1131	(ABC) transporter
FLP23_05715	COG0124	histidyl-tRNA synthetase
FLP23_05720	COG0148	phosphopyruvate hydratase activity
FLP23_05800	COG1704	LemA family
FLP23_05810	COG3214	Protein conserved in bacteria
FLP23_05815	COG3842	ATPase activity
FLP23_05840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLP23_05845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLP23_05860	COG1272	protein, Hemolysin III
FLP23_05865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLP23_05875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FLP23_05885	COG0114	fumarate hydratase activity
FLP23_05900	COG1722	exodeoxyribonuclease VII activity
FLP23_05910	COG1570	exodeoxyribonuclease VII activity
FLP23_05915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLP23_05930	COG0191	fructose-bisphosphate aldolase activity
FLP23_05960	COG3250	beta-galactosidase activity
FLP23_05960	COG5297	Belongs to the glycosyl hydrolase family 6
FLP23_05965	COG1322	Protein conserved in bacteria
FLP23_05990	COG0012	GTP binding
FLP23_06005	COG2066	Belongs to the glutaminase family
FLP23_06030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FLP23_06040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLP23_06045	COG0509	glycine decarboxylation via glycine cleavage system
FLP23_06050	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLP23_06050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLP23_06065	COG4166	transmembrane transport
FLP23_06070	COG0601	transmembrane transport
FLP23_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP23_06085	COG0747	negative chemotaxis
FLP23_06100	COG2837	iron assimilation
FLP23_06105	COG2822	iron ion transport
FLP23_06140	COG2171	N-acyltransferase activity
FLP23_06145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLP23_06165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLP23_06170	COG1012	belongs to the aldehyde dehydrogenase family
FLP23_06185	COG0076	glutamate decarboxylase activity
FLP23_06190	COG0489	protein tyrosine kinase activity
FLP23_06190	COG2151	metal-sulfur cluster biosynthetic enzyme
FLP23_06200	COG2239	Acts as a magnesium transporter
FLP23_06225	COG0006	proline dipeptidase activity
FLP23_06235	COG0613	PHP domain protein
FLP23_06240	COG2801	Transposase and inactivated derivatives
FLP23_06240	COG3415	Transposase
FLP23_06245	COG0513	Belongs to the DEAD box helicase family
FLP23_06280	COG0583	DNA-binding transcription factor activity
FLP23_06310	COG0706	membrane insertase activity
FLP23_06320	COG3655	Transcriptional regulator
FLP23_06345	COG4721	ABC-type cobalt transport system, permease component
FLP23_06350	COG1122	ATPase activity
FLP23_06360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLP23_06380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FLP23_06390	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FLP23_06395	COG2814	Major facilitator Superfamily
FLP23_06415	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_06425	COG0667	Aldo Keto reductase
FLP23_06430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLP23_06480	COG1946	Acyl-CoA thioesterase
FLP23_06530	COG0698	ribose 5-phosphate isomerase
FLP23_06545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLP23_06555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLP23_06570	COG2197	response regulator
FLP23_06585	COG1278	Cold shock
FLP23_06615	COG0544	peptidyl-prolyl cis-trans isomerase activity
FLP23_06625	COG2801	Transposase and inactivated derivatives
FLP23_06625	COG3415	Transposase
FLP23_06635	COG0740	serine-type endopeptidase activity
FLP23_06640	COG0740	serine-type endopeptidase activity
FLP23_06660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLP23_06665	COG3135	benzoate transporter
FLP23_06680	COG0339	signal peptide processing
FLP23_06700	COG0525	valine-tRNA ligase activity
FLP23_06715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLP23_06720	COG0285	dihydrofolate synthase activity
FLP23_06730	COG0105	UTP biosynthetic process
FLP23_06745	COG1530	ribonuclease E activity
FLP23_06760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FLP23_06765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FLP23_06770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLP23_06775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLP23_06780	COG4221	oxidoreductase activity
FLP23_06790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLP23_06800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLP23_06810	COG0799	negative regulation of ribosome biogenesis
FLP23_06855	COG3415	Transposase
FLP23_06855	COG2801	Transposase and inactivated derivatives
FLP23_06875	COG2378	regulation of single-species biofilm formation
FLP23_06880	COG2066	Belongs to the glutaminase family
FLP23_06880	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FLP23_06885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FLP23_06895	COG0477	Major facilitator Superfamily
FLP23_06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_06930	COG2957	Belongs to the agmatine deiminase family
FLP23_06935	COG0154	amidase activity
FLP23_06940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLP23_06945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLP23_06955	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FLP23_07010	COG2815	serine threonine protein kinase
FLP23_07010	COG0515	serine threonine protein kinase
FLP23_07035	COG0366	Alpha amylase catalytic
FLP23_07045	COG4209	transmembrane transport
FLP23_07050	COG0395	ABC-type sugar transport system, permease component
FLP23_07055	COG1472	Belongs to the glycosyl hydrolase 3 family
FLP23_07090	COG0512	Glutamine amidotransferase of anthranilate synthase
FLP23_07090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLP23_07100	COG0495	leucyl-tRNA aminoacylation
FLP23_07105	COG1555	photosystem II stabilization
FLP23_07105	COG1596	polysaccharide export
FLP23_07120	COG0268	Binds directly to 16S ribosomal RNA
FLP23_07130	COG0481	GTPase activity
FLP23_07135	COG1136	(ABC) transporter
FLP23_07135	COG0577	efflux transmembrane transporter activity
FLP23_07160	COG4762	Protein conserved in bacteria
FLP23_07180	COG1420	regulation of RNA biosynthetic process
FLP23_07185	COG0484	heat shock protein binding
FLP23_07200	COG0537	adenosine 5'-monophosphoramidase activity
FLP23_07210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLP23_07230	COG4585	Histidine kinase
FLP23_07235	COG2197	response regulator
FLP23_07240	COG1136	(ABC) transporter
FLP23_07240	COG0577	efflux transmembrane transporter activity
FLP23_07255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLP23_07270	COG2860	membrane
FLP23_07285	COG1595	DNA-templated transcription, initiation
FLP23_07290	COG0328	RNA-DNA hybrid ribonuclease activity
FLP23_07295	COG1381	Involved in DNA repair and RecF pathway recombination
FLP23_07300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLP23_07325	COG1872	DUF167
FLP23_07335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLP23_07340	COG1309	transcriptional regulator
FLP23_07385	COG1185	polyribonucleotide nucleotidyltransferase activity
FLP23_07390	COG0667	Aldo Keto reductase
FLP23_07400	COG0612	Peptidase, M16
FLP23_07415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FLP23_07425	COG1764	response to oxidative stress
FLP23_07440	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FLP23_07455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLP23_07460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLP23_07475	COG1136	(ABC) transporter
FLP23_07475	COG0577	efflux transmembrane transporter activity
FLP23_07480	COG0577	efflux transmembrane transporter activity
FLP23_07485	COG1674	ftsk spoiiie
FLP23_07495	COG1546	Belongs to the CinA family
FLP23_07495	COG1058	Belongs to the CinA family
FLP23_07500	COG1396	sequence-specific DNA binding
FLP23_07510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLP23_07515	COG2137	regulation of response to DNA damage stimulus
FLP23_07520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLP23_07525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLP23_07530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLP23_07540	COG1846	Transcriptional regulator
FLP23_07545	COG2813	Specifically methylates the guanine in position
FLP23_07550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLP23_07565	COG2267	carboxylic ester hydrolase activity
FLP23_07570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLP23_07580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLP23_07585	COG0131	Imidazoleglycerol-phosphate dehydratase
FLP23_07590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLP23_07595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FLP23_07615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLP23_07620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLP23_07625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLP23_07635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLP23_07640	COG0072	phenylalanine-tRNA ligase activity
FLP23_07640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLP23_07655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLP23_07660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FLP23_07665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FLP23_07670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLP23_07675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLP23_07685	COG0165	Argininosuccinate lyase
FLP23_07690	COG2094	Belongs to the DNA glycosylase MPG family
FLP23_07710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLP23_07735	COG0647	UMP catabolic process
FLP23_07745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLP23_07750	COG0497	DNA recombination
FLP23_07755	COG0504	CTP synthase activity
FLP23_07760	COG0494	nUDIX hydrolase
FLP23_07765	COG4974	Belongs to the 'phage' integrase family
FLP23_07775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLP23_07780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLP23_07795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLP23_07800	COG1160	GTP binding
FLP23_07805	COG0477	Major facilitator Superfamily
FLP23_07815	COG0039	L-malate dehydrogenase activity
FLP23_07820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLP23_07840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLP23_07845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLP23_07865	COG1819	glycosyl
FLP23_07895	COG0210	DNA helicase
FLP23_07920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLP23_07980	COG0386	Belongs to the glutathione peroxidase family
FLP23_08010	COG1716	ATPase activity
FLP23_08025	COG1192	Involved in chromosome partitioning
FLP23_08030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FLP23_08060	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FLP23_08065	COG2815	serine threonine protein kinase
FLP23_08065	COG0515	serine threonine protein kinase
FLP23_08070	COG3942	CHAP domain
FLP23_08070	COG1388	LysM domain
FLP23_08090	COG2001	Belongs to the MraZ family
FLP23_08095	COG0275	rRNA processing
FLP23_08100	COG0768	penicillin binding
FLP23_08105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLP23_08115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLP23_08120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLP23_08130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLP23_08135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLP23_08140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLP23_08145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLP23_08155	COG1799	cell septum assembly
FLP23_08165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLP23_08185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLP23_08190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLP23_08195	COG0167	dihydroorotate dehydrogenase activity
FLP23_08205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLP23_08215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLP23_08220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLP23_08240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLP23_08245	COG0723	plastoquinol--plastocyanin reductase activity
FLP23_08250	COG2010	Cytochrome c
FLP23_08255	COG1845	cytochrome c oxidase, subunit III
FLP23_08260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLP23_08265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLP23_08270	COG4214	carbohydrate transport
FLP23_08280	COG4213	ABC transporter substrate-binding protein
FLP23_08285	COG1940	carbohydrate kinase activity
FLP23_08290	COG0456	acetyltransferase
FLP23_08295	COG0137	argininosuccinate synthase activity
FLP23_08300	COG0277	FAD linked oxidase domain protein
FLP23_08315	COG1733	regulation of RNA biosynthetic process
FLP23_08375	COG4702	Belongs to the UPF0303 family
FLP23_08380	COG0494	nUDIX hydrolase
FLP23_08385	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_08400	COG0584	glycerophosphoryl diester phosphodiesterase
FLP23_08415	COG4581	dead DEAH box helicase
FLP23_08420	COG0805	protein transport
FLP23_08425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLP23_08450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLP23_08460	COG1968	undecaprenyl-diphosphatase activity
FLP23_08465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLP23_08495	COG0587	DNA-directed DNA polymerase activity
FLP23_08500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLP23_08520	COG2755	lipolytic protein G-D-S-L family
FLP23_08530	COG0531	amino acid
FLP23_08545	COG0406	alpha-ribazole phosphatase activity
FLP23_08550	COG1403	HNH endonuclease
FLP23_08565	COG0366	Alpha amylase catalytic
FLP23_08575	COG0254	rRNA binding
FLP23_08580	COG1119	ATPase activity
FLP23_08585	COG0297	glycogen (starch) synthase activity
FLP23_08590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLP23_08620	COG0488	(ABC) transporter
FLP23_08625	COG1268	BioY protein
FLP23_08630	COG2151	metal-sulfur cluster biosynthetic enzyme
FLP23_08635	COG0396	ATPase activity
FLP23_08660	COG0109	protoheme IX farnesyltransferase activity
FLP23_08670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLP23_08690	COG0363	glucosamine-6-phosphate deaminase activity
FLP23_08700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLP23_08705	COG0149	triose-phosphate isomerase activity
FLP23_08710	COG0126	phosphoglycerate kinase activity
FLP23_08725	COG1481	regulation of sporulation
FLP23_08730	COG1660	Displays ATPase and GTPase activities
FLP23_08735	COG0322	excinuclease ABC activity
FLP23_08750	COG0556	nucleotide-excision repair
FLP23_08755	COG0237	dephospho-CoA kinase activity
FLP23_08765	COG0539	negative regulation of cytoplasmic translation
FLP23_08770	COG1090	epimerase
FLP23_08780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLP23_08790	COG2050	protein possibly involved in aromatic compounds catabolism
FLP23_08810	COG0469	pyruvate kinase activity
FLP23_08820	COG0070	glutamate synthase
FLP23_08820	COG0067	glutamate synthase
FLP23_08820	COG0069	glutamate synthase activity
FLP23_08825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLP23_08830	COG0159	tryptophan synthase activity
FLP23_08835	COG0133	tryptophan synthase activity
FLP23_08840	COG0134	indole-3-glycerol-phosphate synthase activity
FLP23_08860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLP23_08865	COG0107	imidazoleglycerol-phosphate synthase activity
FLP23_08870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLP23_08875	COG0140	phosphoribosyl-ATP diphosphatase activity
FLP23_08880	COG0545	Peptidyl-prolyl cis-trans isomerase
FLP23_08890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLP23_08900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLP23_08910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLP23_08920	COG1758	RNA polymerase activity
FLP23_08925	COG0194	GDP metabolic process
FLP23_08930	COG0284	orotidine-5'-phosphate decarboxylase activity
FLP23_08935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLP23_08940	COG0505	Belongs to the CarA family
FLP23_08950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLP23_08955	COG0540	Belongs to the ATCase OTCase family
FLP23_08960	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLP23_08965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLP23_08975	COG1116	anion transmembrane transporter activity
FLP23_08980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLP23_08985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLP23_08990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLP23_08995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLP23_09000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLP23_09005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLP23_09010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLP23_09020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLP23_09025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLP23_09035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLP23_09050	COG1196	nuclear chromosome segregation
FLP23_09060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLP23_09065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLP23_09070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLP23_09080	COG2255	four-way junction helicase activity
FLP23_09085	COG0632	four-way junction helicase activity
FLP23_09090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FLP23_09095	COG0217	transcriptional regulatory protein
FLP23_09110	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FLP23_09115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FLP23_09125	COG1404	Belongs to the peptidase S8 family
FLP23_09130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLP23_09170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FLP23_09210	COG0183	Belongs to the thiolase family
FLP23_09215	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLP23_09215	COG1024	Enoyl-CoA hydratase
FLP23_09230	COG2814	Major facilitator Superfamily
FLP23_09235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLP23_09240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLP23_09255	COG0756	dUTP diphosphatase activity
FLP23_09280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLP23_09290	COG0187	DNA topoisomerase II activity
FLP23_09320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLP23_09335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLP23_09340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLP23_09345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP23_09355	COG0321	lipoyl(octanoyl) transferase activity
FLP23_09360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FLP23_09380	COG0174	glutamine synthetase
FLP23_09385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FLP23_09395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FLP23_09395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLP23_09405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FLP23_09425	COG1278	Cold shock
FLP23_09440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLP23_09470	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FLP23_09485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLP23_09490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLP23_09540	COG0438	transferase activity, transferring glycosyl groups
FLP23_09565	COG2197	response regulator
FLP23_09580	COG2197	response regulator
FLP23_09585	COG4585	Histidine kinase
FLP23_09600	COG4608	Belongs to the ABC transporter superfamily
FLP23_09610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLP23_09615	COG0601	transmembrane transport
FLP23_09645	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FLP23_09660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLP23_09675	COG0438	transferase activity, transferring glycosyl groups
FLP23_09690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLP23_09740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLP23_09745	COG0438	transferase activity, transferring glycosyl groups
FLP23_09750	COG0110	maltose O-acetyltransferase activity
FLP23_09760	COG0423	glycine-tRNA ligase activity
FLP23_09780	COG1104	cysteine desulfurase activity
FLP23_09790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLP23_09795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLP23_09820	COG0277	FAD linked oxidase domain protein
FLP23_09830	COG1216	Glycosyl transferase, family 2
FLP23_09845	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_09860	COG1793	dna ligase
FLP23_09860	COG3285	dna ligase
FLP23_09895	COG1027	Aspartate ammonia-lyase
FLP23_09965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLP23_09970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLP23_09995	COG0584	glycerophosphoryl diester phosphodiesterase
FLP23_10000	COG1012	belongs to the aldehyde dehydrogenase family
FLP23_10005	COG1012	belongs to the aldehyde dehydrogenase family
FLP23_10010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLP23_10015	COG2390	Transcriptional regulator
FLP23_10025	COG2807	transmembrane transport
FLP23_10045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLP23_10050	COG1309	transcriptional regulator
FLP23_10055	COG0477	Major facilitator Superfamily
FLP23_10080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLP23_10090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_10100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLP23_10105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLP23_10130	COG0442	prolyl-tRNA aminoacylation
FLP23_10145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLP23_10160	COG0750	zinc metalloprotease
FLP23_10170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLP23_10180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLP23_10205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLP23_10210	COG1177	transmembrane transport
FLP23_10215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLP23_10220	COG3842	ATPase activity
FLP23_10230	COG0686	Belongs to the AlaDH PNT family
FLP23_10255	COG0714	Associated with various cellular activities
FLP23_10280	COG1012	belongs to the aldehyde dehydrogenase family
FLP23_10290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLP23_10295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLP23_10300	COG0667	Aldo Keto reductase
FLP23_10305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLP23_10310	COG0519	Catalyzes the synthesis of GMP from XMP
FLP23_10315	COG3022	response to hydroperoxide
FLP23_10325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLP23_10330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLP23_10335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLP23_10340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FLP23_10345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLP23_10350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLP23_10360	COG0356	it plays a direct role in the translocation of protons across the membrane
FLP23_10370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLP23_10385	COG2890	protein-(glutamine-N5) methyltransferase activity
FLP23_10390	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLP23_10400	COG0083	homoserine kinase activity
FLP23_10410	COG0460	homoserine dehydrogenase
FLP23_10415	COG0019	diaminopimelate decarboxylase activity
FLP23_10425	COG0018	arginyl-trna synthetase
FLP23_10445	COG1929	Belongs to the glycerate kinase type-1 family
FLP23_10450	COG1595	DNA-templated transcription, initiation
FLP23_10460	COG0010	Belongs to the arginase family
FLP23_10485	COG0601	transmembrane transport
FLP23_10490	COG4608	Belongs to the ABC transporter superfamily
FLP23_10495	COG4172	Belongs to the ABC transporter superfamily
FLP23_10500	COG0747	negative chemotaxis
FLP23_10525	COG1131	(ABC) transporter
FLP23_10560	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FLP23_10575	COG0477	Major facilitator Superfamily
FLP23_10590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLP23_10610	COG2814	Major facilitator Superfamily
FLP23_10625	COG0765	amino acid transport
FLP23_10630	COG1126	abc transporter atp-binding protein
FLP23_10640	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FLP23_10645	COG1902	pentaerythritol trinitrate reductase activity
FLP23_10665	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLP23_10665	COG0567	Dehydrogenase, E1 component
FLP23_10670	COG2186	Transcriptional regulator
FLP23_10680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLP23_10690	COG4948	Mandelate Racemase Muconate Lactonizing
FLP23_10710	COG1028	Short-chain dehydrogenase reductase Sdr
FLP23_10725	COG1595	DNA-templated transcription, initiation
FLP23_10730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLP23_10735	COG1162	GTPase activity
FLP23_10740	COG0483	inositol monophosphate 1-phosphatase activity
FLP23_10745	COG4213	ABC transporter substrate-binding protein
FLP23_10755	COG4214	carbohydrate transport
FLP23_10765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLP23_10770	COG2079	MmgE PrpD family protein
FLP23_10785	COG0433	COG0433 Predicted ATPase
FLP23_10800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FLP23_10840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FLP23_10920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLP23_10925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FLP23_10930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLP23_10965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLP23_10985	COG2089	acid synthase
FLP23_11020	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLP23_11025	COG3609	addiction module antidote protein, CC2985 family
FLP23_11045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLP23_11075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLP23_11095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FLP23_11100	COG1615	UPF0182 protein
FLP23_11105	COG3480	Lon protease (S16) C-terminal proteolytic domain
FLP23_11120	COG0739	heme binding
FLP23_11160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLP23_11170	COG1983	PspC domain protein
FLP23_11215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLP23_11220	COG0154	amidase activity
FLP23_11225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLP23_11235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLP23_11240	COG0482	sulfurtransferase activity
FLP23_11255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLP23_11295	COG0366	Alpha amylase catalytic
FLP23_11300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLP23_11350	COG0575	Belongs to the CDS family
FLP23_11355	COG0233	cytoplasmic translational termination
FLP23_11365	COG0528	UMP kinase activity
FLP23_11380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLP23_11385	COG0052	Belongs to the universal ribosomal protein uS2 family
FLP23_11400	COG4974	Belongs to the 'phage' integrase family
FLP23_11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLP23_11485	COG0792	nuclease activity
FLP23_11500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLP23_11510	COG0335	large ribosomal subunit rRNA binding
FLP23_11525	COG0336	Belongs to the RNA methyltransferase TrmD family
FLP23_11535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLP23_11540	COG1837	Belongs to the UPF0109 family
FLP23_11545	COG0228	four-way junction DNA binding
FLP23_11555	COG1120	ATPase activity
FLP23_11560	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLP23_11565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLP23_11570	COG4592	Periplasmic binding protein
FLP23_11590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FLP23_11630	COG0406	alpha-ribazole phosphatase activity
FLP23_11645	COG1196	nuclear chromosome segregation
FLP23_11650	COG0456	acetyltransferase
FLP23_11665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLP23_11670	COG0571	ribonuclease III activity
FLP23_11675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FLP23_11685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLP23_11690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLP23_11695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLP23_11700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLP23_11700	COG1116	anion transmembrane transporter activity
FLP23_11715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLP23_11740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLP23_11745	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FLP23_11760	COG0714	Associated with various cellular activities
FLP23_11765	COG0778	Nitroreductase
FLP23_11765	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FLP23_11770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_11780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLP23_11805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLP23_11820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLP23_11835	COG0742	ribosomal rna small subunit methyltransferase
FLP23_11850	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLP23_11855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FLP23_11870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLP23_11875	COG0066	3-isopropylmalate dehydratase activity
FLP23_11880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLP23_11940	COG1674	ftsk spoiiie
FLP23_11955	COG0714	Associated with various cellular activities
FLP23_12015	COG1597	lipid kinase activity
FLP23_12020	COG2217	Heavy metal translocating P-type atpase
FLP23_12030	COG3458	cephalosporin-C deacetylase activity
FLP23_12040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLP23_12050	COG0583	DNA-binding transcription factor activity
FLP23_12060	COG4989	oxidoreductase activity
FLP23_12075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLP23_12105	COG2176	DNA-directed DNA polymerase activity
FLP23_12110	COG2855	membrane
FLP23_12115	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLP23_12130	COG0473	3-isopropylmalate dehydrogenase activity