locus-tag	class	description
LG3211_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LG3211_0004	COG0187	DNA topoisomerase II activity
LG3211_0006	COG0501	Belongs to the peptidase M48B family
LG3211_0013	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LG3211_0015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG3211_0021	COG0583	DNA-binding transcription factor activity
LG3211_0025	COG3273	potassium ion transport
LG3211_0025	COG0471	metal ion transport
LG3211_0026	COG2205	protein histidine kinase activity
LG3211_0027	COG0784	Response regulator, receiver
LG3211_0037	COG2204	response regulator
LG3211_0046	COG0745	RESPONSE REGULATOR receiver
LG3211_0047	COG0642	Histidine kinase
LG3211_0051	COG1595	DNA-templated transcription, initiation
LG3211_0052	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG3211_0053	COG2197	response regulator
LG3211_0054	COG4585	Histidine kinase
LG3211_0066	COG3186	Phenylalanine-4-hydroxylase
LG3211_0068	COG1522	sequence-specific DNA binding
LG3211_0069	COG1794	racemase activity, acting on amino acids and derivatives
LG3211_0078	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LG3211_0084	COG2853	Lipoprotein
LG3211_0087	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LG3211_0088	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LG3211_0089	COG1127	ABC transporter
LG3211_0091	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LG3211_0092	COG1074	ATP-dependent DNA helicase activity
LG3211_0102	COG5001	Diguanylate cyclase
LG3211_0102	COG3300	MHYT domain
LG3211_0105	COG1136	(ABC) transporter
LG3211_0105	COG0577	efflux transmembrane transporter activity
LG3211_0109	COG0577	efflux transmembrane transporter activity
LG3211_0109	COG1136	(ABC) transporter
LG3211_0113	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LG3211_0115	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LG3211_0116	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG3211_0120	COG0753	catalase activity
LG3211_0121	COG1595	DNA-templated transcription, initiation
LG3211_0126	COG2194	sulfuric ester hydrolase activity
LG3211_0128	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LG3211_0129	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG3211_0130	COG2188	Transcriptional regulator
LG3211_0131	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LG3211_0132	COG0363	glucosamine-6-phosphate deaminase activity
LG3211_0133	COG0129	dihydroxy-acid dehydratase activity
LG3211_0135	COG0546	phosphoglycolate phosphatase activity
LG3211_0136	COG0800	Aldolase
LG3211_0137	COG1609	Transcriptional regulator
LG3211_0138	COG2050	protein possibly involved in aromatic compounds catabolism
LG3211_0142	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG3211_0150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG3211_0158	COG0405	Gamma-glutamyltransferase
LG3211_0165	COG2205	protein histidine kinase activity
LG3211_0165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG3211_0166	COG5001	Diguanylate cyclase
LG3211_0166	COG4251	negative regulation of phosphorylation
LG3211_0166	COG2203	Gaf domain
LG3211_0166	COG3706	GGDEF domain
LG3211_0169	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LG3211_0178	COG1309	transcriptional regulator
LG3211_0179	COG2130	NADP-dependent
LG3211_0182	COG1881	PFAM PEBP family protein
LG3211_0187	COG1968	undecaprenyl-diphosphatase activity
LG3211_0189	COG0174	glutamine synthetase
LG3211_0190	COG0454	-acetyltransferase
LG3211_0193	COG0004	ammonium transporteR
LG3211_0196	COG1404	Belongs to the peptidase S8 family
LG3211_0198	COG4771	TonB-dependent receptor
LG3211_0201	COG1609	Transcriptional regulator
LG3211_0204	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LG3211_0206	COG1999	signal sequence binding
LG3211_0209	COG4792	protein secretion
LG3211_0211	COG1987	bacterial-type flagellum assembly
LG3211_0212	COG4790	Type iii secretion
LG3211_0213	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG3211_0214	COG4566	intracellular signal transduction
LG3211_0215	COG4191	Histidine kinase
LG3211_0218	COG4789	Type iii secretion
LG3211_0233	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LG3211_0233	COG2755	lipolytic protein G-D-S-L family
LG3211_0237	COG0438	transferase activity, transferring glycosyl groups
LG3211_0244	COG3795	YCII-related domain
LG3211_0245	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LG3211_0246	COG4941	Belongs to the sigma-70 factor family
LG3211_0248	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LG3211_0257	COG2132	Multicopper oxidase
LG3211_0258	COG0545	Peptidyl-prolyl cis-trans isomerase
LG3211_0264	COG0861	Integral membrane protein TerC family
LG3211_0266	COG1446	asparaginase
LG3211_0271	COG4106	trans-aconitate 2-methyltransferase activity
LG3211_0285	COG3712	iron ion homeostasis
LG3211_0289	COG3250	beta-galactosidase activity
LG3211_0290	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0291	COG0800	Aldolase
LG3211_0292	COG4948	Mandelate Racemase Muconate Lactonizing
LG3211_0294	COG3734	2-keto-3-deoxy-galactonokinase
LG3211_0296	COG3345	alpha-galactosidase
LG3211_0305	COG1609	Transcriptional regulator
LG3211_0308	COG2755	lipolytic protein G-D-S-L family
LG3211_0309	COG2272	Belongs to the type-B carboxylesterase lipase family
LG3211_0312	COG0431	NADPH-dependent FMN reductase
LG3211_0315	COG3275	phosphorelay sensor kinase activity
LG3211_0316	COG3279	Response regulator of the LytR AlgR family
LG3211_0320	COG0596	Alpha beta hydrolase
LG3211_0321	COG3852	Histidine kinase
LG3211_0323	COG2032	superoxide dismutase activity
LG3211_0328	COG0183	Belongs to the thiolase family
LG3211_0329	COG3119	arylsulfatase activity
LG3211_0339	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG3211_0340	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LG3211_0341	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LG3211_0348	COG1131	(ABC) transporter
LG3211_0354	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG3211_0356	COG0477	Major facilitator Superfamily
LG3211_0357	COG0583	DNA-binding transcription factor activity
LG3211_0361	COG0612	Peptidase, M16
LG3211_0363	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG3211_0366	COG1842	Phage shock protein A
LG3211_0371	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LG3211_0373	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG3211_0374	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG3211_0377	COG0583	DNA-binding transcription factor activity
LG3211_0380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG3211_0383	COG0596	Alpha beta hydrolase
LG3211_0384	COG0318	PFAM AMP-dependent synthetase and ligase
LG3211_0385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG3211_0389	COG0612	Peptidase, M16
LG3211_0390	COG0564	pseudouridine synthase activity
LG3211_0394	COG1802	Transcriptional regulator
LG3211_0395	COG3291	Pkd domain containing protein
LG3211_0396	COG0583	DNA-binding transcription factor activity
LG3211_0398	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LG3211_0399	COG2224	Isocitrate lyase
LG3211_0407	COG0596	Alpha beta hydrolase
LG3211_0417	COG2963	transposase activity
LG3211_0418	COG2801	Transposase and inactivated derivatives
LG3211_0420	COG4974	Belongs to the 'phage' integrase family
LG3211_0421	COG0606	chelatase, subunit chli
LG3211_0423	COG0347	Belongs to the P(II) protein family
LG3211_0424	COG0583	DNA-binding transcription factor activity
LG3211_0425	COG2855	membrane
LG3211_0430	COG1166	arginine decarboxylase activity
LG3211_0433	COG2084	Dehydrogenase
LG3211_0437	COG0018	arginyl-trna synthetase
LG3211_0438	COG2003	Belongs to the UPF0758 family
LG3211_0440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG3211_0446	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LG3211_0448	COG0708	Exodeoxyribonuclease III
LG3211_0449	COG2807	transmembrane transport
LG3211_0452	COG0739	heme binding
LG3211_0453	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LG3211_0461	COG2234	aminopeptidase activity
LG3211_0464	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LG3211_0465	COG4942	peptidase
LG3211_0466	COG0793	Belongs to the peptidase S41A family
LG3211_0470	COG2258	MOSC domain
LG3211_0479	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG3211_0480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG3211_0482	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LG3211_0486	COG1612	heme a metabolic process
LG3211_0487	COG0109	protoheme IX farnesyltransferase activity
LG3211_0488	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG3211_0492	COG4946	Tricorn protease homolog
LG3211_0492	COG1506	peptidase
LG3211_0492	COG0823	Involved in the tonB-independent uptake of proteins
LG3211_0496	COG0358	DNA primase activity
LG3211_0497	COG1295	ribonuclease BN
LG3211_0498	COG1610	YqeY-like protein
LG3211_0499	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LG3211_0500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LG3211_0501	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LG3211_0506	COG4206	TonB-dependent receptor
LG3211_0507	COG0617	tRNA 3'-terminal CCA addition
LG3211_0509	COG1090	epimerase
LG3211_0510	COG0741	lytic transglycosylase activity
LG3211_0510	COG1196	nuclear chromosome segregation
LG3211_0510	COG0739	heme binding
LG3211_0512	COG0730	response to heat
LG3211_0519	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG3211_0522	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LG3211_0526	COG0366	Alpha amylase catalytic
LG3211_0528	COG4771	TonB-dependent receptor
LG3211_0530	COG1874	Beta-galactosidase
LG3211_0530	COG0366	Alpha amylase catalytic
LG3211_0532	COG0601	transmembrane transport
LG3211_0539	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LG3211_0541	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LG3211_0542	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LG3211_0545	COG2207	Transcriptional regulator
LG3211_0555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG3211_0559	COG1397	ADP-ribosylglycohydrolase
LG3211_0561	COG4946	Tricorn protease homolog
LG3211_0561	COG1506	peptidase
LG3211_0561	COG0823	Involved in the tonB-independent uptake of proteins
LG3211_0563	COG1307	EDD domain protein, DegV family
LG3211_0566	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG3211_0567	COG3964	amidohydrolase
LG3211_0573	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LG3211_0577	COG0436	Aminotransferase
LG3211_0583	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0584	COG2851	Citrate transporter
LG3211_0587	COG0642	Histidine kinase
LG3211_0588	COG1840	ABC-type Fe3 transport system, periplasmic component
LG3211_0589	COG0280	phosphate acetyltransferase
LG3211_0589	COG0281	malic enzyme
LG3211_0593	COG0583	DNA-binding transcription factor activity
LG3211_0597	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LG3211_0600	COG2801	Transposase and inactivated derivatives
LG3211_0601	COG2963	transposase activity
LG3211_0609	COG2814	Major facilitator Superfamily
LG3211_0618	COG1522	sequence-specific DNA binding
LG3211_0619	COG3386	PFAM SMP-30 Gluconolaconase
LG3211_0623	COG3795	YCII-related domain
LG3211_0627	COG1131	(ABC) transporter
LG3211_0628	COG0842	Transport permease protein
LG3211_0630	COG1113	amino acid transport
LG3211_0631	COG2304	oxidoreductase activity
LG3211_0637	COG2706	6-phosphogluconolactonase activity
LG3211_0638	COG0667	Aldo Keto reductase
LG3211_0642	COG4991	sh3 domain protein
LG3211_0650	COG0534	Mate efflux family protein
LG3211_0651	COG2807	transmembrane transport
LG3211_0659	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_0660	COG1538	Outer membrane efflux protein
LG3211_0662	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG3211_0665	COG1690	Belongs to the RtcB family
LG3211_0673	COG1335	isochorismatase
LG3211_0675	COG1522	sequence-specific DNA binding
LG3211_0690	COG4181	ATPase activity
LG3211_0691	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LG3211_0694	COG2813	Specifically methylates the guanine in position
LG3211_0695	COG1187	pseudouridine synthase activity
LG3211_0696	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG3211_0698	COG1666	GTP binding
LG3211_0699	COG1064	alcohol dehydrogenase
LG3211_0701	COG0697	spore germination
LG3211_0706	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG3211_0708	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG3211_0712	COG0356	it plays a direct role in the translocation of protons across the membrane
LG3211_0714	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LG3211_0715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LG3211_0716	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LG3211_0718	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LG3211_0719	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LG3211_0723	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LG3211_0726	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0727	COG0640	Transcriptional regulator
LG3211_0728	COG2205	protein histidine kinase activity
LG3211_0728	COG0745	RESPONSE REGULATOR receiver
LG3211_0728	COG4191	Histidine kinase
LG3211_0734	COG0577	efflux transmembrane transporter activity
LG3211_0734	COG1136	(ABC) transporter
LG3211_0738	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG3211_0739	COG2801	Transposase and inactivated derivatives
LG3211_0740	COG2963	transposase activity
LG3211_0751	COG4206	TonB-dependent receptor
LG3211_0754	COG1956	GAF domain-containing protein
LG3211_0755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LG3211_0757	COG0720	synthase
LG3211_0759	COG1051	belongs to the nudix hydrolase family
LG3211_0760	COG2906	2 iron, 2 sulfur cluster binding
LG3211_0784	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0789	COG0625	glutathione transferase activity
LG3211_0796	COG0151	Belongs to the GarS family
LG3211_0798	COG0138	bifunctional purine biosynthesis protein purh
LG3211_0800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LG3211_0801	COG2267	carboxylic ester hydrolase activity
LG3211_0802	COG2453	phosphatase
LG3211_0802	COG0671	phosphoesterase, PA-phosphatase related
LG3211_0807	COG4589	Belongs to the CDS family
LG3211_0810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LG3211_0812	COG2264	protein methyltransferase activity
LG3211_0815	COG0439	Biotin carboxylase
LG3211_0817	COG0511	ligase activity, forming carbon-carbon bonds
LG3211_0818	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LG3211_0820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG3211_0821	COG4232	protein-disulfide reductase activity
LG3211_0822	COG1324	tolerance protein
LG3211_0825	COG0392	lysyltransferase activity
LG3211_0825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LG3211_0827	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0827	COG0604	alcohol dehydrogenase
LG3211_0827	COG3321	synthase
LG3211_0828	COG2356	endonuclease I
LG3211_0833	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LG3211_0846	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LG3211_0849	COG0778	Nitroreductase
LG3211_0850	COG2353	YceI-like domain
LG3211_0851	COG1741	Belongs to the pirin family
LG3211_0855	COG1560	Kdo2-lipid A biosynthetic process
LG3211_0856	COG1519	Transferase
LG3211_0857	COG1538	Outer membrane efflux protein
LG3211_0858	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LG3211_0859	COG1309	transcriptional regulator
LG3211_0861	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_0864	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LG3211_0866	COG0473	3-isopropylmalate dehydrogenase activity
LG3211_0869	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG3211_0872	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG3211_0876	COG0129	dihydroxy-acid dehydratase activity
LG3211_0879	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LG3211_0880	COG0083	homoserine kinase activity
LG3211_0882	COG1881	PFAM PEBP family protein
LG3211_0885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LG3211_0887	COG3710	Transcriptional regulator
LG3211_0887	COG0457	Tetratricopeptide repeat
LG3211_0891	COG1404	Belongs to the peptidase S8 family
LG3211_0892	COG4104	PAAR repeat-containing protein
LG3211_0896	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LG3211_0902	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LG3211_0909	COG0563	adenylate kinase activity
LG3211_0910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LG3211_0911	COG0586	Pfam SNARE associated Golgi protein
LG3211_0914	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_0917	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG3211_0918	COG0537	adenosine 5'-monophosphoramidase activity
LG3211_0919	COG4774	siderophore transport
LG3211_0920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG3211_0921	COG0352	thiamine-phosphate diphosphorylase activity
LG3211_0922	COG1773	rubredoxin
LG3211_0929	COG1132	(ABC) transporter
LG3211_0930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG3211_0934	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LG3211_0935	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LG3211_0940	COG0006	proline dipeptidase activity
LG3211_0941	COG0583	DNA-binding transcription factor activity
LG3211_0946	COG0006	proline dipeptidase activity
LG3211_0949	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG3211_0952	COG0346	lactoylglutathione lyase activity
LG3211_0953	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LG3211_0954	COG1561	YicC-like family, N-terminal region
LG3211_0956	COG1758	RNA polymerase activity
LG3211_0958	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG3211_0963	COG4771	TonB-dependent receptor
LG3211_0964	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LG3211_0967	COG0254	rRNA binding
LG3211_0969	COG0372	Belongs to the citrate synthase family
LG3211_0979	COG0714	Associated with various cellular activities
LG3211_0985	COG1301	dicarboxylic acid transport
LG3211_0986	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LG3211_0988	COG3300	MHYT domain
LG3211_0988	COG5001	Diguanylate cyclase
LG3211_0991	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LG3211_0992	COG4149	molybdate abc transporter
LG3211_0993	COG0725	ABC transporter, periplasmic molybdate-binding protein
LG3211_0997	COG3047	cAMP biosynthetic process
LG3211_0998	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG3211_1005	COG0667	Aldo Keto reductase
LG3211_1008	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG3211_1014	COG0126	phosphoglycerate kinase activity
LG3211_1020	COG0469	pyruvate kinase activity
LG3211_1022	COG3588	fructose-bisphosphate aldolase
LG3211_1028	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_1031	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG3211_1034	COG1970	mechanosensitive ion channel activity
LG3211_1040	COG2022	thiamine diphosphate biosynthetic process
LG3211_1052	COG0189	ligase activity
LG3211_1052	COG4067	protein conserved in archaea
LG3211_1053	COG0189	ligase activity
LG3211_1054	COG0745	RESPONSE REGULATOR receiver
LG3211_1055	COG0642	Histidine kinase
LG3211_1057	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG3211_1059	COG3291	Pkd domain containing protein
LG3211_1060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LG3211_1070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LG3211_1073	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LG3211_1076	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG3211_1077	COG3422	double-strand break repair
LG3211_1080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG3211_1081	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LG3211_1082	COG0745	RESPONSE REGULATOR receiver
LG3211_1082	COG3706	GGDEF domain
LG3211_1083	COG2119	membrane
LG3211_1086	COG0667	Aldo Keto reductase
LG3211_1089	COG4771	TonB-dependent receptor
LG3211_1092	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG3211_1095	COG0330	HflC and HflK could
LG3211_1102	COG0509	glycine decarboxylation via glycine cleavage system
LG3211_1111	COG1408	metallophosphoesterase
LG3211_1116	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG3211_1118	COG2814	Major facilitator Superfamily
LG3211_1121	COG1960	acyl-CoA dehydrogenase activity
LG3211_1122	COG1309	transcriptional regulator
LG3211_1123	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LG3211_1131	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LG3211_1133	COG0463	Glycosyl transferase, family 2
LG3211_1135	COG2982	Protein involved in outer membrane biogenesis
LG3211_1136	COG1272	protein, Hemolysin III
LG3211_1141	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LG3211_1143	COG0739	heme binding
LG3211_1145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG3211_1146	COG0626	cystathionine gamma-synthase activity
LG3211_1147	COG0460	homoserine dehydrogenase
LG3211_1147	COG0527	aspartate kinase activity
LG3211_1158	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LG3211_1158	COG2010	Cytochrome c
LG3211_1160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LG3211_1163	COG1760	l-serine dehydratase
LG3211_1166	COG3038	cytochrome b561
LG3211_1168	COG0784	Response regulator, receiver
LG3211_1168	COG2198	Histidine kinase
LG3211_1168	COG2205	protein histidine kinase activity
LG3211_1173	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LG3211_1177	COG1335	isochorismatase
LG3211_1180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LG3211_1181	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LG3211_1184	COG0259	pyridoxamine-phosphate oxidase activity
LG3211_1198	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LG3211_1203	COG2963	transposase activity
LG3211_1204	COG2801	Transposase and inactivated derivatives
LG3211_1206	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LG3211_1220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LG3211_1221	COG0519	Catalyzes the synthesis of GMP from XMP
LG3211_1222	COG1678	Uncharacterized ACR, COG1678
LG3211_1223	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LG3211_1225	COG2824	Alkylphosphonate utilization operon protein PhnA
LG3211_1226	COG2239	Acts as a magnesium transporter
LG3211_1228	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LG3211_1233	COG1660	Displays ATPase and GTPase activities
LG3211_1234	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LG3211_1235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG3211_1238	COG1137	ATPase activity
LG3211_1239	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LG3211_1241	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LG3211_1243	COG0271	Belongs to the BolA IbaG family
LG3211_1247	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LG3211_1248	COG4774	siderophore transport
LG3211_1249	COG3454	Phosphonate metabolism
LG3211_1250	COG2188	Transcriptional regulator
LG3211_1251	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LG3211_1258	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG3211_1264	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LG3211_1266	COG0628	permease
LG3211_1267	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LG3211_1269	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LG3211_1270	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LG3211_1271	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LG3211_1274	COG1648	precorrin-2 dehydrogenase activity
LG3211_1274	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LG3211_1276	COG0583	DNA-binding transcription factor activity
LG3211_1280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG3211_1281	COG0175	sulfate reduction
LG3211_1282	COG0529	Catalyzes the synthesis of activated sulfate
LG3211_1282	COG2895	sulfate adenylyltransferase (ATP) activity
LG3211_1288	COG1477	protein flavinylation
LG3211_1293	COG4774	siderophore transport
LG3211_1296	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LG3211_1298	COG0719	Fe-S assembly protein
LG3211_1299	COG0396	ATPase activity
LG3211_1302	COG0719	Fe-S assembly protein
LG3211_1306	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1310	COG0697	spore germination
LG3211_1316	COG4264	IucA IucC family
LG3211_1320	COG0019	diaminopimelate decarboxylase activity
LG3211_1322	COG1280	lysine exporter protein (LysE YggA)
LG3211_1324	COG3264	Mechanosensitive ion channel
LG3211_1324	COG1511	domain protein
LG3211_1327	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG3211_1328	COG1764	response to oxidative stress
LG3211_1329	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG3211_1337	COG0625	glutathione transferase activity
LG3211_1340	COG1902	pentaerythritol trinitrate reductase activity
LG3211_1340	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG3211_1343	COG1196	nuclear chromosome segregation
LG3211_1345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG3211_1346	COG0604	alcohol dehydrogenase
LG3211_1349	COG2814	Major facilitator Superfamily
LG3211_1350	COG0583	DNA-binding transcription factor activity
LG3211_1351	COG3384	dioxygenase
LG3211_1353	COG2885	chlorophyll binding
LG3211_1356	COG1187	pseudouridine synthase activity
LG3211_1361	COG1063	alcohol dehydrogenase
LG3211_1369	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG3211_1370	COG0588	phosphoglycerate mutase activity
LG3211_1372	COG0285	dihydrofolate synthase activity
LG3211_1376	COG2833	Protein of unknown function (DUF455)
LG3211_1379	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LG3211_1381	COG0735	belongs to the Fur family
LG3211_1391	COG1228	amidohydrolase
LG3211_1393	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG3211_1401	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG3211_1411	COG0583	DNA-binding transcription factor activity
LG3211_1414	COG0456	acetyltransferase
LG3211_1419	COG1056	cytidyltransferase-related domain
LG3211_1419	COG1051	belongs to the nudix hydrolase family
LG3211_1422	COG0604	alcohol dehydrogenase
LG3211_1422	COG3321	synthase
LG3211_1424	COG2827	Endonuclease containing a URI domain
LG3211_1425	COG3239	Fatty acid desaturase
LG3211_1426	COG0640	Transcriptional regulator
LG3211_1429	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG3211_1431	COG0513	Belongs to the DEAD box helicase family
LG3211_1437	COG4771	TonB-dependent receptor
LG3211_1443	COG0583	DNA-binding transcription factor activity
LG3211_1445	COG0656	L-ascorbic acid biosynthetic process
LG3211_1450	COG0243	molybdopterin cofactor binding
LG3211_1451	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LG3211_1463	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG3211_1464	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LG3211_1471	COG2814	Major facilitator Superfamily
LG3211_1472	COG0640	Transcriptional regulator
LG3211_1474	COG1301	dicarboxylic acid transport
LG3211_1476	COG1051	belongs to the nudix hydrolase family
LG3211_1477	COG0612	Peptidase, M16
LG3211_1483	COG0791	NLP P60 protein
LG3211_1484	COG0791	NLP P60 protein
LG3211_1486	COG2311	Membrane
LG3211_1492	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG3211_1494	COG1506	peptidase
LG3211_1494	COG4946	Tricorn protease homolog
LG3211_1494	COG0823	Involved in the tonB-independent uptake of proteins
LG3211_1496	COG3214	Protein conserved in bacteria
LG3211_1505	COG0504	CTP synthase activity
LG3211_1507	COG0148	phosphopyruvate hydratase activity
LG3211_1508	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LG3211_1514	COG2197	response regulator
LG3211_1515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LG3211_1516	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LG3211_1517	COG1238	metal cluster binding
LG3211_1529	COG1534	Rna-binding protein
LG3211_1530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LG3211_1531	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG3211_1532	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LG3211_1534	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LG3211_1535	COG1923	regulation of RNA biosynthetic process
LG3211_1536	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LG3211_1537	COG0330	HflC and HflK could
LG3211_1538	COG0330	HflC and HflK could
LG3211_1543	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG3211_1554	COG0583	DNA-binding transcription factor activity
LG3211_1558	COG2234	aminopeptidase activity
LG3211_1563	COG2972	Histidine kinase
LG3211_1570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG3211_1570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG3211_1571	COG0346	lactoylglutathione lyase activity
LG3211_1572	COG2814	Major facilitator Superfamily
LG3211_1574	COG0531	amino acid
LG3211_1576	COG4245	von Willebrand factor, type A
LG3211_1586	COG3710	Transcriptional regulator
LG3211_1591	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG3211_1599	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LG3211_1600	COG2894	cell division
LG3211_1601	COG0850	regulation of cytokinetic process
LG3211_1603	COG4585	Histidine kinase
LG3211_1607	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LG3211_1609	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LG3211_1616	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LG3211_1624	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LG3211_1629	COG1595	DNA-templated transcription, initiation
LG3211_1632	COG1946	Acyl-CoA thioesterase
LG3211_1636	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LG3211_1636	COG0116	Belongs to the methyltransferase superfamily
LG3211_1637	COG3963	phosphatidate phosphatase activity
LG3211_1643	COG1741	Belongs to the pirin family
LG3211_1647	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LG3211_1656	COG4771	TonB-dependent receptor
LG3211_1660	COG3734	2-keto-3-deoxy-galactonokinase
LG3211_1661	COG0800	Aldolase
LG3211_1662	COG3878	Protein conserved in bacteria
LG3211_1665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LG3211_1667	COG0745	RESPONSE REGULATOR receiver
LG3211_1668	COG2205	protein histidine kinase activity
LG3211_1671	COG4452	Inner membrane protein CreD
LG3211_1674	COG0671	phosphoesterase, PA-phosphatase related
LG3211_1675	COG0438	transferase activity, transferring glycosyl groups
LG3211_1676	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LG3211_1677	COG2943	transferase activity, transferring hexosyl groups
LG3211_1678	COG0318	PFAM AMP-dependent synthetase and ligase
LG3211_1679	COG0248	Ppx GppA phosphatase
LG3211_1680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LG3211_1682	COG0745	RESPONSE REGULATOR receiver
LG3211_1683	COG4783	chaperone-mediated protein folding
LG3211_1687	COG0473	3-isopropylmalate dehydrogenase activity
LG3211_1690	COG1757	Na H antiporter
LG3211_1692	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG3211_1693	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LG3211_1695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LG3211_1696	COG0631	protein serine/threonine phosphatase activity
LG3211_1703	COG0859	PFAM glycosyl transferase family 9
LG3211_1704	COG3642	lipopolysaccharide core region biosynthetic process
LG3211_1708	COG0315	cyclic pyranopterin monophosphate synthase activity
LG3211_1710	COG0314	molybdopterin synthase activity
LG3211_1719	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LG3211_1720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LG3211_1722	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LG3211_1723	COG0537	adenosine 5'-monophosphoramidase activity
LG3211_1727	COG0714	Associated with various cellular activities
LG3211_1731	COG1399	metal-binding, possibly nucleic acid-binding protein
LG3211_1733	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG3211_1735	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1737	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1739	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG3211_1741	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG3211_1742	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LG3211_1745	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG3211_1745	COG1024	Enoyl-CoA hydratase
LG3211_1749	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG3211_1750	COG0481	GTPase activity
LG3211_1751	COG0681	Belongs to the peptidase S26 family
LG3211_1753	COG0571	ribonuclease III activity
LG3211_1754	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LG3211_1762	COG1472	Belongs to the glycosyl hydrolase 3 family
LG3211_1764	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LG3211_1765	COG1278	Cold shock
LG3211_1766	COG1960	acyl-CoA dehydrogenase activity
LG3211_1773	COG1132	(ABC) transporter
LG3211_1777	COG5001	Diguanylate cyclase
LG3211_1778	COG2304	oxidoreductase activity
LG3211_1779	COG1012	belongs to the aldehyde dehydrogenase family
LG3211_1782	COG1570	exodeoxyribonuclease VII activity
LG3211_1783	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LG3211_1784	COG0671	phosphoesterase, PA-phosphatase related
LG3211_1785	COG1404	Belongs to the peptidase S8 family
LG3211_1789	COG1404	Belongs to the peptidase S8 family
LG3211_1795	COG0167	dihydroorotate dehydrogenase activity
LG3211_1801	COG1012	belongs to the aldehyde dehydrogenase family
LG3211_1806	COG2963	transposase activity
LG3211_1807	COG2801	Transposase and inactivated derivatives
LG3211_1817	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LG3211_1824	COG0642	Histidine kinase
LG3211_1832	COG3250	beta-galactosidase activity
LG3211_1835	COG1501	Belongs to the glycosyl hydrolase 31 family
LG3211_1837	COG1070	Carbohydrate kinase
LG3211_1839	COG0477	Major facilitator Superfamily
LG3211_1840	COG1472	Belongs to the glycosyl hydrolase 3 family
LG3211_1842	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LG3211_1844	COG3534	alpha-L-arabinofuranosidase
LG3211_1848	COG2801	Transposase and inactivated derivatives
LG3211_1849	COG2963	transposase activity
LG3211_1854	COG4991	sh3 domain protein
LG3211_1861	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1862	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LG3211_1863	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1867	COG1509	lysine 2,3-aminomutase activity
LG3211_1871	COG0402	S-adenosylhomocysteine deaminase activity
LG3211_1875	COG1469	GTP cyclohydrolase I activity
LG3211_1876	COG3706	GGDEF domain
LG3211_1876	COG0745	RESPONSE REGULATOR receiver
LG3211_1879	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG3211_1881	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG3211_1883	COG2166	iron-sulfur cluster assembly
LG3211_1887	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LG3211_1888	COG0137	argininosuccinate synthase activity
LG3211_1889	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG3211_1890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LG3211_1892	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LG3211_1893	COG0442	prolyl-tRNA aminoacylation
LG3211_1894	COG0165	Argininosuccinate lyase
LG3211_1895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LG3211_1898	COG3279	Response regulator of the LytR AlgR family
LG3211_1899	COG3275	phosphorelay sensor kinase activity
LG3211_1900	COG2020	methyltransferase activity
LG3211_1903	COG1309	transcriptional regulator
LG3211_1904	COG0583	DNA-binding transcription factor activity
LG3211_1909	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1911	COG0583	DNA-binding transcription factor activity
LG3211_1912	COG0625	glutathione transferase activity
LG3211_1913	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_1914	COG0583	DNA-binding transcription factor activity
LG3211_1915	COG0154	amidase activity
LG3211_1918	COG1215	transferase activity, transferring glycosyl groups
LG3211_1919	COG1649	PFAM Uncharacterised BCR, COG1649
LG3211_1919	COG0726	polysaccharide deacetylase
LG3211_1920	COG0457	Tetratricopeptide repeat
LG3211_1927	COG0726	polysaccharide deacetylase
LG3211_1941	COG2986	histidine ammonia-lyase
LG3211_1943	COG5001	Diguanylate cyclase
LG3211_1943	COG3300	MHYT domain
LG3211_1946	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LG3211_1947	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LG3211_1948	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LG3211_1948	COG0131	Imidazoleglycerol-phosphate dehydratase
LG3211_1950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LG3211_1952	COG0140	phosphoribosyl-ATP diphosphatase activity
LG3211_1952	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LG3211_1959	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LG3211_1962	COG0531	amino acid
LG3211_1963	COG0531	amino acid
LG3211_1968	COG3708	Transcriptional regulator
LG3211_1968	COG2207	Transcriptional regulator
LG3211_1969	COG3511	phospholipase C
LG3211_1972	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LG3211_1992	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG3211_1993	COG0251	oxidation-reduction process
LG3211_1997	COG1595	DNA-templated transcription, initiation
LG3211_1999	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG3211_2001	COG0583	DNA-binding transcription factor activity
LG3211_2003	COG1764	response to oxidative stress
LG3211_2008	COG0583	DNA-binding transcription factor activity
LG3211_2010	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG3211_2012	COG3459	Glycosyltransferase 36 associated
LG3211_2023	COG1024	Enoyl-CoA hydratase
LG3211_2025	COG1918	ferrous iron import across plasma membrane
LG3211_2025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LG3211_2032	COG0443	Heat shock 70 kDa protein
LG3211_2033	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG3211_2036	COG0183	Belongs to the thiolase family
LG3211_2039	COG1960	acyl-CoA dehydrogenase activity
LG3211_2045	COG1703	isobutyryl-CoA mutase activity
LG3211_2045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LG3211_2045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LG3211_2046	COG4935	Belongs to the peptidase S8 family
LG3211_2046	COG2234	aminopeptidase activity
LG3211_2053	COG2963	transposase activity
LG3211_2054	COG2801	Transposase and inactivated derivatives
LG3211_2060	COG1819	glycosyl
LG3211_2067	COG3590	peptidase
LG3211_2084	COG0596	Alpha beta hydrolase
LG3211_2089	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LG3211_2099	COG1309	transcriptional regulator
LG3211_2102	COG0456	acetyltransferase
LG3211_2108	COG0560	Phosphoserine phosphatase
LG3211_2116	COG0251	oxidation-reduction process
LG3211_2119	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LG3211_2120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LG3211_2124	COG0673	inositol 2-dehydrogenase activity
LG3211_2126	COG0477	Major facilitator Superfamily
LG3211_2128	COG1451	nucleotide metabolic process
LG3211_2133	COG0438	transferase activity, transferring glycosyl groups
LG3211_2150	COG2081	HI0933 family
LG3211_2152	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG3211_2155	COG0583	DNA-binding transcription factor activity
LG3211_2159	COG4953	penicillin-binding protein 1C
LG3211_2161	COG2373	Large extracellular alpha-helical protein
LG3211_2165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG3211_2169	COG0457	Tetratricopeptide repeat
LG3211_2169	COG3710	Transcriptional regulator
LG3211_2170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG3211_2171	COG3015	lipoprotein NlpE involved in copper resistance
LG3211_2172	COG0433	COG0433 Predicted ATPase
LG3211_2177	COG0688	phosphatidylethanolamine metabolic process
LG3211_2178	COG1999	signal sequence binding
LG3211_2179	COG2890	protein-(glutamine-N5) methyltransferase activity
LG3211_2181	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LG3211_2183	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LG3211_2187	COG0133	tryptophan synthase activity
LG3211_2188	COG0159	tryptophan synthase activity
LG3211_2189	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LG3211_2190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG3211_2191	COG3083	sulfuric ester hydrolase activity
LG3211_2196	COG0149	triose-phosphate isomerase activity
LG3211_2199	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LG3211_2200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LG3211_2201	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LG3211_2202	COG0649	NAD binding
LG3211_2203	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LG3211_2204	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LG3211_2206	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LG3211_2207	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LG3211_2209	COG0713	ATP synthesis coupled electron transport
LG3211_2212	COG1007	ATP synthesis coupled electron transport
LG3211_2216	COG0195	Participates in both transcription termination and antitermination
LG3211_2219	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LG3211_2223	COG1185	polyribonucleotide nucleotidyltransferase activity
LG3211_2236	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_2239	COG0583	DNA-binding transcription factor activity
LG3211_2249	COG4191	Histidine kinase
LG3211_2250	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LG3211_2251	COG0587	DNA-directed DNA polymerase activity
LG3211_2257	COG1090	epimerase
LG3211_2267	COG1024	Enoyl-CoA hydratase
LG3211_2268	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LG3211_2270	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LG3211_2280	COG4191	Histidine kinase
LG3211_2280	COG0784	Response regulator, receiver
LG3211_2289	COG1294	oxidase, subunit
LG3211_2290	COG4890	Cyd operon protein YbgT
LG3211_2292	COG0589	response to stress
LG3211_2296	COG4251	negative regulation of phosphorylation
LG3211_2297	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LG3211_2300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LG3211_2302	COG0497	DNA recombination
LG3211_2304	COG1420	regulation of RNA biosynthetic process
LG3211_2305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LG3211_2306	COG0443	Heat shock 70 kDa protein
LG3211_2307	COG0484	heat shock protein binding
LG3211_2312	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LG3211_2313	COG0505	Belongs to the CarA family
LG3211_2315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG3211_2317	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG3211_2321	COG0326	Molecular chaperone. Has ATPase activity
LG3211_2324	COG1446	asparaginase
LG3211_2329	COG4206	TonB-dependent receptor
LG3211_2330	COG3537	Alpha-1,2-mannosidase
LG3211_2331	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LG3211_2333	COG4206	TonB-dependent receptor
LG3211_2336	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LG3211_2339	COG2205	protein histidine kinase activity
LG3211_2339	COG2198	Histidine kinase
LG3211_2339	COG0784	Response regulator, receiver
LG3211_2340	COG1024	Enoyl-CoA hydratase
LG3211_2341	COG0318	PFAM AMP-dependent synthetase and ligase
LG3211_2344	COG0583	DNA-binding transcription factor activity
LG3211_2345	COG2828	Protein conserved in bacteria
LG3211_2348	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG3211_2352	COG1049	propionate catabolic process, 2-methylcitrate cycle
LG3211_2354	COG2915	High frequency lysogenization protein hflD homolog
LG3211_2358	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LG3211_2359	COG0542	response to heat
LG3211_2365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LG3211_2368	COG0492	ferredoxin-NADP+ reductase activity
LG3211_2370	COG0686	Belongs to the AlaDH PNT family
LG3211_2372	COG1674	ftsk spoiiie
LG3211_2376	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LG3211_2377	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LG3211_2382	COG2831	hemolysin activation secretion protein
LG3211_2384	COG0811	peptide transport
LG3211_2395	COG1177	transmembrane transport
LG3211_2396	COG1176	ABC-type spermidine putrescine transport system, permease component I
LG3211_2397	COG3842	ATPase activity
LG3211_2398	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LG3211_2403	COG0583	DNA-binding transcription factor activity
LG3211_2409	COG0789	Transcriptional regulator
LG3211_2410	COG2217	Heavy metal translocating P-type atpase
LG3211_2411	COG1201	RNA secondary structure unwinding
LG3211_2417	COG1285	pathogenesis
LG3211_2419	COG2823	Periplasmic or secreted lipoprotein
LG3211_2423	COG2223	nitrite transmembrane transporter activity
LG3211_2424	COG2207	Transcriptional regulator
LG3211_2429	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LG3211_2431	COG3346	SURF1 family
LG3211_2432	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG3211_2433	COG1845	cytochrome c oxidase, subunit III
LG3211_2434	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG3211_2435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG3211_2437	COG1104	cysteine desulfurase activity
LG3211_2442	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_2444	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_2445	COG1538	Outer membrane efflux protein
LG3211_2453	COG3135	benzoate transporter
LG3211_2461	COG2203	Gaf domain
LG3211_2461	COG5001	Diguanylate cyclase
LG3211_2461	COG4251	negative regulation of phosphorylation
LG3211_2461	COG3706	GGDEF domain
LG3211_2462	COG1404	Belongs to the peptidase S8 family
LG3211_2465	COG1280	lysine exporter protein (LysE YggA)
LG3211_2471	COG3321	synthase
LG3211_2477	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LG3211_2478	COG1132	(ABC) transporter
LG3211_2480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_2481	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_2482	COG1349	DNA-binding transcription factor activity
LG3211_2491	COG3591	Belongs to the peptidase S1B family
LG3211_2494	COG0243	molybdopterin cofactor binding
LG3211_2496	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG3211_2497	COG2223	nitrite transmembrane transporter activity
LG3211_2498	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG3211_2498	COG1116	anion transmembrane transporter activity
LG3211_2499	COG3707	response regulator
LG3211_2500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LG3211_2500	COG1648	precorrin-2 dehydrogenase activity
LG3211_2502	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LG3211_2502	COG2885	chlorophyll binding
LG3211_2507	COG3501	Rhs element vgr protein
LG3211_2511	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LG3211_2524	COG2205	protein histidine kinase activity
LG3211_2524	COG0784	Response regulator, receiver
LG3211_2539	COG0659	secondary active sulfate transmembrane transporter activity
LG3211_2544	COG2824	Alkylphosphonate utilization operon protein PhnA
LG3211_2546	COG0596	Alpha beta hydrolase
LG3211_2548	COG4774	siderophore transport
LG3211_2549	COG0738	Major facilitator superfamily
LG3211_2550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG3211_2551	COG1940	carbohydrate kinase activity
LG3211_2551	COG1846	Transcriptional regulator
LG3211_2557	COG3345	alpha-galactosidase
LG3211_2559	COG1012	belongs to the aldehyde dehydrogenase family
LG3211_2560	COG2271	Major facilitator Superfamily
LG3211_2564	COG0583	DNA-binding transcription factor activity
LG3211_2570	COG0583	DNA-binding transcription factor activity
LG3211_2571	COG1404	Belongs to the peptidase S8 family
LG3211_2575	COG2932	Transcriptional regulator
LG3211_2581	COG2801	Transposase and inactivated derivatives
LG3211_2582	COG2963	transposase activity
LG3211_2590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG3211_2591	COG0673	inositol 2-dehydrogenase activity
LG3211_2592	COG1477	protein flavinylation
LG3211_2594	COG2211	Major facilitator Superfamily
LG3211_2596	COG1082	Xylose isomerase domain protein TIM barrel
LG3211_2597	COG3622	Belongs to the hyi family
LG3211_2599	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LG3211_2600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LG3211_2601	COG2080	2 iron, 2 sulfur cluster binding
LG3211_2604	COG0277	FAD linked oxidase domain protein
LG3211_2605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG3211_2612	COG0596	Alpha beta hydrolase
LG3211_2617	COG2132	Multicopper oxidase
LG3211_2623	COG2197	response regulator
LG3211_2624	COG2885	chlorophyll binding
LG3211_2628	COG0415	Belongs to the DNA photolyase family
LG3211_2631	COG1404	Belongs to the peptidase S8 family
LG3211_2636	COG3134	Outer membrane lipoprotein
LG3211_2639	COG0739	heme binding
LG3211_2641	COG0305	Participates in initiation and elongation during chromosome replication
LG3211_2643	COG0359	binds to the 23S rRNA
LG3211_2644	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LG3211_2652	COG0017	Asparaginyl-tRNA synthetase
LG3211_2660	COG0714	Associated with various cellular activities
LG3211_2667	COG0288	reversible hydration of carbon dioxide
LG3211_2668	COG0251	oxidation-reduction process
LG3211_2669	COG0662	Cupin 2, conserved barrel domain protein
LG3211_2671	COG3844	kynureninase activity
LG3211_2673	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG3211_2674	COG2925	Exonuclease
LG3211_2677	COG2814	Major facilitator Superfamily
LG3211_2684	COG1113	amino acid transport
LG3211_2688	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG3211_2689	COG2902	Dehydrogenase
LG3211_2690	COG1960	acyl-CoA dehydrogenase activity
LG3211_2697	COG1309	transcriptional regulator
LG3211_2701	COG2900	Belongs to the SlyX family
LG3211_2703	COG0545	Peptidyl-prolyl cis-trans isomerase
LG3211_2705	COG0386	Belongs to the glutathione peroxidase family
LG3211_2707	COG1725	Transcriptional regulator
LG3211_2708	COG1131	(ABC) transporter
LG3211_2712	COG4682	membrane
LG3211_2719	COG2850	peptidyl-arginine hydroxylation
LG3211_2721	COG0567	Dehydrogenase, E1 component
LG3211_2726	COG0604	alcohol dehydrogenase
LG3211_2732	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LG3211_2734	COG4953	penicillin-binding protein 1C
LG3211_2736	COG2373	Large extracellular alpha-helical protein
LG3211_2739	COG3227	Zinc metalloprotease (Elastase)
LG3211_2741	COG3227	Zinc metalloprotease (Elastase)
LG3211_2742	COG5507	3-demethylubiquinone-9 3-methyltransferase
LG3211_2744	COG2353	YceI-like domain
LG3211_2747	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LG3211_2750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LG3211_2751	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LG3211_2766	COG3842	ATPase activity
LG3211_2767	COG2723	6-phospho-beta-galactosidase activity
LG3211_2768	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LG3211_2769	COG0837	glucose binding
LG3211_2770	COG0363	glucosamine-6-phosphate deaminase activity
LG3211_2773	COG0395	ABC-type sugar transport system, permease component
LG3211_2774	COG1175	transmembrane transport
LG3211_2775	COG1653	transport
LG3211_2780	COG2350	Protein conserved in bacteria
LG3211_2783	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LG3211_2784	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LG3211_2785	COG1187	pseudouridine synthase activity
LG3211_2788	COG1309	transcriptional regulator
LG3211_2815	COG2948	multi-organism process
LG3211_2819	COG0436	Aminotransferase
LG3211_2826	COG1138	Cytochrome C-type biogenesis protein
LG3211_2830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG3211_2838	COG0583	DNA-binding transcription factor activity
LG3211_2847	COG3243	poly(R)-hydroxyalkanoic acid synthase
LG3211_2849	COG1183	phosphatidylcholine synthase activity
LG3211_2852	COG2205	protein histidine kinase activity
LG3211_2853	COG4771	TonB-dependent receptor
LG3211_2854	COG2610	gluconate transmembrane transporter activity
LG3211_2858	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG3211_2864	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LG3211_2866	COG0668	transmembrane transport
LG3211_2868	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LG3211_2873	COG0590	tRNA wobble adenosine to inosine editing
LG3211_2875	COG1309	transcriptional regulator
LG3211_2878	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG3211_2878	COG0519	Catalyzes the synthesis of GMP from XMP
LG3211_2881	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LG3211_2888	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LG3211_2891	COG1160	GTP binding
LG3211_2892	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LG3211_2896	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LG3211_2897	COG0105	UTP biosynthetic process
LG3211_2899	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG3211_2899	COG1024	Enoyl-CoA hydratase
LG3211_2900	COG0183	Belongs to the thiolase family
LG3211_2903	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG3211_2904	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG3211_2906	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LG3211_2909	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LG3211_2911	COG0776	regulation of translation
LG3211_2912	COG0539	negative regulation of cytoplasmic translation
LG3211_2915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LG3211_2917	COG2957	Belongs to the agmatine deiminase family
LG3211_2919	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG3211_2927	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_2931	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LG3211_2931	COG0316	Belongs to the HesB IscA family
LG3211_2935	COG0564	pseudouridine synthase activity
LG3211_2937	COG1530	ribonuclease E activity
LG3211_2941	COG4221	oxidoreductase activity
LG3211_2942	COG2207	Transcriptional regulator
LG3211_2946	COG2259	Doxx family
LG3211_2948	COG3220	belongs to the UPF0276 family
LG3211_2951	COG1764	response to oxidative stress
LG3211_2955	COG0745	RESPONSE REGULATOR receiver
LG3211_2956	COG2205	protein histidine kinase activity
LG3211_2965	COG0583	DNA-binding transcription factor activity
LG3211_2976	COG2801	Transposase and inactivated derivatives
LG3211_2978	COG2963	transposase activity
LG3211_2979	COG2801	Transposase and inactivated derivatives
LG3211_2980	COG2963	transposase activity
LG3211_2981	COG4695	Portal protein
LG3211_2983	COG2963	transposase activity
LG3211_2985	COG0583	DNA-binding transcription factor activity
LG3211_2986	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG3211_2987	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LG3211_2992	COG1605	Chorismate mutase
LG3211_2992	COG0077	Prephenate dehydratase
LG3211_2993	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LG3211_2994	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LG3211_2995	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LG3211_2996	COG1716	ATPase activity
LG3211_3002	COG4221	oxidoreductase activity
LG3211_3010	COG1393	Belongs to the ArsC family
LG3211_3011	COG0069	glutamate synthase activity
LG3211_3013	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LG3211_3015	COG3706	GGDEF domain
LG3211_3016	COG1404	Belongs to the peptidase S8 family
LG3211_3018	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_3020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG3211_3021	COG0583	DNA-binding transcription factor activity
LG3211_3029	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LG3211_3038	COG0322	excinuclease ABC activity
LG3211_3039	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG3211_3040	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LG3211_3041	COG1663	tetraacyldisaccharide 4'-kinase activity
LG3211_3043	COG0848	biopolymer transport protein
LG3211_3044	COG0811	peptide transport
LG3211_3047	COG4591	ABC-type transport system involved in lipoprotein release permease component
LG3211_3054	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LG3211_3055	COG2009	succinate dehydrogenase
LG3211_3057	COG0367	asparagine synthase
LG3211_3058	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LG3211_3059	COG0625	glutathione transferase activity
LG3211_3061	COG1960	acyl-CoA dehydrogenase activity
LG3211_3065	COG0084	hydrolase, TatD family'
LG3211_3066	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LG3211_3069	COG4104	PAAR repeat-containing protein
LG3211_3082	COG2133	pyrroloquinoline quinone binding
LG3211_3083	COG2183	response to ionizing radiation
LG3211_3085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG3211_3088	COG0386	Belongs to the glutathione peroxidase family
LG3211_3089	COG4771	TonB-dependent receptor
LG3211_3091	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG3211_3093	COG0339	signal peptide processing
LG3211_3095	COG5295	Hep Hag repeat protein
LG3211_3096	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LG3211_3097	COG0584	glycerophosphoryl diester phosphodiesterase
LG3211_3099	COG0531	amino acid
LG3211_3100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LG3211_3102	COG1187	pseudouridine synthase activity
LG3211_3109	COG0625	glutathione transferase activity
LG3211_3123	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LG3211_3124	COG0625	glutathione transferase activity
LG3211_3125	COG2223	nitrite transmembrane transporter activity
LG3211_3126	COG1349	DNA-binding transcription factor activity
LG3211_3129	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG3211_3129	COG0519	Catalyzes the synthesis of GMP from XMP
LG3211_3130	COG0564	pseudouridine synthase activity
LG3211_3131	COG4681	YaeQ
LG3211_3132	COG2081	HI0933 family
LG3211_3134	COG0412	Dienelactone hydrolase
LG3211_3136	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LG3211_3137	COG1984	allophanate hydrolase subunit 2
LG3211_3139	COG0515	serine threonine protein kinase
LG3211_3142	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LG3211_3147	COG1714	RDD family
LG3211_3148	COG0717	Belongs to the dCTP deaminase family
LG3211_3150	COG0489	protein tyrosine kinase activity
LG3211_3154	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG3211_3154	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG3211_3155	COG2878	Part of a membrane complex involved in electron transport
LG3211_3158	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LG3211_3160	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG3211_3161	COG0802	atpase or kinase
LG3211_3162	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LG3211_3162	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LG3211_3163	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LG3211_3165	COG0166	Belongs to the GPI family
LG3211_3166	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LG3211_3167	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LG3211_3168	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LG3211_3170	COG0617	tRNA 3'-terminal CCA addition
LG3211_3173	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LG3211_3177	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG3211_3179	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LG3211_3180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LG3211_3181	COG0352	thiamine-phosphate diphosphorylase activity
LG3211_3181	COG0351	phosphomethylpyrimidine kinase
LG3211_3185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LG3211_3186	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LG3211_3188	COG2205	protein histidine kinase activity
LG3211_3189	COG0745	RESPONSE REGULATOR receiver
LG3211_3193	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LG3211_3194	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LG3211_3195	COG2137	regulation of response to DNA damage stimulus
LG3211_3196	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LG3211_3198	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG3211_3199	COG0456	acetyltransferase
LG3211_3199	COG1846	Transcriptional regulator
LG3211_3200	COG1546	Belongs to the CinA family
LG3211_3205	COG0010	Belongs to the arginase family
LG3211_3213	COG2130	NADP-dependent
LG3211_3214	COG0477	Major facilitator Superfamily
LG3211_3218	COG0531	amino acid
LG3211_3219	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LG3211_3220	COG0542	response to heat
LG3211_3221	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LG3211_3224	COG0534	Mate efflux family protein
LG3211_3227	COG0335	large ribosomal subunit rRNA binding
LG3211_3228	COG0336	Belongs to the RNA methyltransferase TrmD family
LG3211_3232	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LG3211_3233	COG4137	Cytochrome C assembly protein
LG3211_3237	COG1566	PFAM secretion protein HlyD family protein
LG3211_3238	COG2814	Major facilitator Superfamily
LG3211_3240	COG1024	Enoyl-CoA hydratase
LG3211_3240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LG3211_3253	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LG3211_3255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LG3211_3256	COG0196	riboflavin kinase activity
LG3211_3257	COG0728	peptidoglycan biosynthetic process
LG3211_3259	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LG3211_3260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LG3211_3263	COG1404	Belongs to the peptidase S8 family
LG3211_3266	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LG3211_3276	COG1024	Enoyl-CoA hydratase
LG3211_3278	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LG3211_3281	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LG3211_3282	COG0573	inorganic phosphate transmembrane transporter activity
LG3211_3283	COG0581	inorganic phosphate transmembrane transporter activity
LG3211_3286	COG0704	Plays a role in the regulation of phosphate uptake
LG3211_3289	COG3220	belongs to the UPF0276 family
LG3211_3291	COG2259	Doxx family
LG3211_3292	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LG3211_3295	COG2076	Multidrug Resistance protein
LG3211_3296	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG3211_3297	COG0557	exoribonuclease II activity
LG3211_3302	COG0475	glutathione-regulated potassium exporter activity
LG3211_3302	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG3211_3305	COG0367	asparagine synthase
LG3211_3308	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG3211_3309	COG1393	Belongs to the ArsC family
LG3211_3312	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LG3211_3313	COG0024	Methionine aminopeptidase
LG3211_3323	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LG3211_3324	COG0575	Belongs to the CDS family
LG3211_3325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LG3211_3328	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LG3211_3330	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LG3211_3338	COG1902	pentaerythritol trinitrate reductase activity
LG3211_3340	COG1722	exodeoxyribonuclease VII activity
LG3211_3341	COG0142	geranyltranstransferase activity
LG3211_3345	COG0312	modulator of DNA gyrase
LG3211_3346	COG3028	Belongs to the UPF0307 family
LG3211_3347	COG0312	modulator of DNA gyrase
LG3211_3348	COG3164	Protein of unknown function
LG3211_3349	COG1530	ribonuclease E activity
LG3211_3350	COG0424	maF-like protein
LG3211_3355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LG3211_3357	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG3211_3363	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LG3211_3364	COG0740	serine-type endopeptidase activity
LG3211_3365	COG0544	peptidyl-prolyl cis-trans isomerase activity
LG3211_3377	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LG3211_3381	COG0495	leucyl-tRNA aminoacylation
LG3211_3392	COG3118	belongs to the thioredoxin family
LG3211_3398	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LG3211_3403	COG3706	GGDEF domain
LG3211_3403	COG5001	Diguanylate cyclase
LG3211_3403	COG2203	Gaf domain
LG3211_3403	COG4251	negative regulation of phosphorylation
LG3211_3405	COG2963	transposase activity
LG3211_3406	COG2801	Transposase and inactivated derivatives
LG3211_3407	COG0513	Belongs to the DEAD box helicase family
LG3211_3411	COG1131	(ABC) transporter
LG3211_3415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LG3211_3416	COG3590	peptidase
LG3211_3418	COG3590	peptidase
LG3211_3437	COG0306	phosphate transporter
LG3211_3440	COG1253	flavin adenine dinucleotide binding
LG3211_3442	COG5001	Diguanylate cyclase
LG3211_3442	COG3300	MHYT domain
LG3211_3452	COG2226	methyltransferase
LG3211_3454	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG3211_3455	COG1862	Preprotein translocase
LG3211_3456	COG0343	queuine tRNA-ribosyltransferase activity
LG3211_3457	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LG3211_3458	COG2197	response regulator
LG3211_3459	COG4585	Histidine kinase
LG3211_3464	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG3211_3470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG3211_3472	COG0405	Gamma-glutamyltransferase
LG3211_3473	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LG3211_3476	COG0742	ribosomal rna small subunit methyltransferase
LG3211_3477	COG0552	protein localization to endoplasmic reticulum
LG3211_3480	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LG3211_3483	COG3153	acetyltransferase
LG3211_3484	COG3811	Belongs to the UPF0386 family
LG3211_3497	COG0477	Major facilitator Superfamily
LG3211_3504	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG3211_3516	COG0515	serine threonine protein kinase
LG3211_3516	COG2815	serine threonine protein kinase
LG3211_3520	COG1960	acyl-CoA dehydrogenase activity
LG3211_3532	COG0776	regulation of translation
LG3211_3534	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LG3211_3537	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LG3211_3538	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LG3211_3540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LG3211_3543	COG5265	(ABC) transporter
LG3211_3547	COG0556	nucleotide-excision repair
LG3211_3548	COG4968	Prepilin-type N-terminal cleavage methylation domain
LG3211_3555	COG2963	transposase activity
LG3211_3556	COG2801	Transposase and inactivated derivatives
LG3211_3558	COG1196	nuclear chromosome segregation
LG3211_3561	COG4695	Portal protein
LG3211_3570	COG3179	chitinase
LG3211_3591	COG1611	Belongs to the LOG family
LG3211_3593	COG2095	MarC family integral membrane protein
LG3211_3595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LG3211_3601	COG2835	tetraacyldisaccharide 4'-kinase activity
LG3211_3604	COG2969	positive regulation of protein catabolic process
LG3211_3605	COG0625	glutathione transferase activity
LG3211_3606	COG2857	Cytochrome c1
LG3211_3607	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LG3211_3608	COG0723	plastoquinol--plastocyanin reductase activity
LG3211_3609	COG0741	lytic transglycosylase activity
LG3211_3611	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LG3211_3616	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LG3211_3618	COG0842	Transport permease protein
LG3211_3618	COG1129	ABC transporter
LG3211_3620	COG1309	transcriptional regulator
LG3211_3622	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG3211_3626	COG1702	phosphate starvation-inducible protein PhoH
LG3211_3627	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LG3211_3635	COG4969	Belongs to the N-Me-Phe pilin family
LG3211_3640	COG4535	Mg2 and Co2 transporter CorC
LG3211_3645	COG1966	Carbon starvation protein
LG3211_3648	COG0823	Involved in the tonB-independent uptake of proteins
LG3211_3648	COG1506	peptidase
LG3211_3649	COG1297	OPT oligopeptide transporter protein
LG3211_3651	COG3104	oligopeptide transport
LG3211_3658	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG3211_3659	COG0837	glucose binding
LG3211_3660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LG3211_3665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG3211_3670	COG0438	transferase activity, transferring glycosyl groups
LG3211_3673	COG0438	transferase activity, transferring glycosyl groups
LG3211_3686	COG1834	amidinotransferase
LG3211_3694	COG0318	PFAM AMP-dependent synthetase and ligase
LG3211_3699	COG2963	transposase activity
LG3211_3700	COG2801	Transposase and inactivated derivatives
LG3211_3703	COG0142	geranyltranstransferase activity
LG3211_3705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LG3211_3707	COG0527	aspartate kinase activity
LG3211_3708	COG0384	phenazine biosynthesis protein PhzF
LG3211_3715	COG0477	Major facilitator Superfamily
LG3211_3718	COG2205	protein histidine kinase activity
LG3211_3721	COG0039	L-malate dehydrogenase activity
LG3211_3725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LG3211_3733	COG0154	amidase activity
LG3211_3736	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LG3211_3737	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LG3211_3738	COG0203	ribosomal protein L17
LG3211_3739	COG0202	RNA polymerase activity
LG3211_3740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LG3211_3741	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LG3211_3742	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LG3211_3743	COG0201	protein transport
LG3211_3744	COG0200	Binds to the 23S rRNA
LG3211_3745	COG1841	ribosomal large subunit assembly
LG3211_3746	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LG3211_3747	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LG3211_3749	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LG3211_3750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LG3211_3752	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LG3211_3753	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LG3211_3754	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LG3211_3755	COG0255	Belongs to the universal ribosomal protein uL29 family
LG3211_3756	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LG3211_3757	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LG3211_3758	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LG3211_3759	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LG3211_3760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LG3211_3761	COG0089	rRNA binding
LG3211_3762	COG0088	Forms part of the polypeptide exit tunnel
LG3211_3763	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LG3211_3764	COG0051	transcription antitermination factor activity, RNA binding
LG3211_3765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG3211_3766	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG3211_3767	COG0049	tRNA binding
LG3211_3769	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LG3211_3770	COG0085	RNA polymerase activity
LG3211_3772	COG0222	ribosome binding
LG3211_3773	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LG3211_3774	COG0081	regulation of translation
LG3211_3775	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LG3211_3776	COG0250	Participates in transcription elongation, termination and antitermination
LG3211_3777	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LG3211_3779	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG3211_3784	COG0012	GTP binding
LG3211_3785	COG0193	aminoacyl-tRNA hydrolase activity
LG3211_3787	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LG3211_3793	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LG3211_3794	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LG3211_3795	COG0456	acetyltransferase
LG3211_3798	COG0521	Mo-molybdopterin cofactor biosynthetic process
LG3211_3800	COG2326	polyphosphate kinase activity
LG3211_3805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG3211_3806	COG1295	ribonuclease BN
LG3211_3810	COG0252	asparaginase activity
LG3211_3821	COG3291	Pkd domain containing protein
LG3211_3826	COG1309	transcriptional regulator
LG3211_3827	COG1404	Belongs to the peptidase S8 family
LG3211_3829	COG1404	Belongs to the peptidase S8 family
LG3211_3832	COG1404	Belongs to the peptidase S8 family
LG3211_3840	COG4807	Protein conserved in bacteria
LG3211_3841	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LG3211_3842	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LG3211_3848	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LG3211_3853	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG3211_3856	COG1216	Glycosyl transferase, family 2
LG3211_3859	COG0438	transferase activity, transferring glycosyl groups
LG3211_3859	COG1216	Glycosyl transferase, family 2
LG3211_3870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG3211_3871	COG0450	alkyl hydroperoxide reductase
LG3211_3872	COG0583	DNA-binding transcription factor activity
LG3211_3873	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LG3211_3885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG3211_3886	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG3211_3888	COG2096	Adenosyltransferase
LG3211_3889	COG0123	including yeast histone deacetylase and acetoin utilization protein
LG3211_3890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG3211_3891	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LG3211_3892	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG3211_3893	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LG3211_3894	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LG3211_3895	COG2967	ApaG domain
LG3211_3896	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LG3211_3897	COG3738	Protein conserved in bacteria
LG3211_3898	COG0318	PFAM AMP-dependent synthetase and ligase
LG3211_3901	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LG3211_3905	COG1704	LemA family
LG3211_3906	COG0861	Integral membrane protein TerC family
LG3211_3907	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LG3211_3909	COG0577	efflux transmembrane transporter activity
LG3211_3909	COG1136	(ABC) transporter
LG3211_3910	COG1136	(ABC) transporter
LG3211_3911	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_3912	COG0642	Histidine kinase
LG3211_3913	COG0745	RESPONSE REGULATOR receiver
LG3211_3919	COG3956	TIGRFAM MazG family protein
LG3211_3921	COG0494	nUDIX hydrolase
LG3211_3923	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LG3211_3926	COG2201	protein-glutamate methylesterase activity
LG3211_3934	COG2198	Histidine kinase
LG3211_3934	COG0643	Histidine kinase
LG3211_3935	COG0840	transmembrane signaling receptor activity
LG3211_3939	COG0189	ligase activity
LG3211_3941	COG1858	cytochrome C peroxidase
LG3211_3948	COG1199	ATP-dependent helicase activity
LG3211_3950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG3211_3955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG3211_3959	COG1643	Atp-dependent helicase
LG3211_3960	COG0783	Belongs to the Dps family
LG3211_3964	COG0514	ATP-dependent DNA helicase (RecQ)
LG3211_3977	COG4695	Portal protein
LG3211_3981	COG0602	queuosine metabolic process
LG3211_3983	COG2885	chlorophyll binding
LG3211_3984	COG0823	Involved in the tonB-independent uptake of proteins
LG3211_3987	COG0848	biopolymer transport protein
LG3211_3989	COG0824	Thioesterase
LG3211_3990	COG2255	four-way junction helicase activity
LG3211_3992	COG3158	transport of potassium into the cell
LG3211_3994	COG0632	four-way junction helicase activity
LG3211_3995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LG3211_3996	COG0217	transcriptional regulatory protein
LG3211_4004	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LG3211_4007	COG0488	(ABC) transporter
LG3211_4010	COG4651	solute:proton antiporter activity
LG3211_4010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG3211_4011	COG3132	Protein of unknown function, DUF480
LG3211_4015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LG3211_4017	COG1492	cobalamin metabolic process
LG3211_4019	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LG3211_4024	COG4206	TonB-dependent receptor
LG3211_4027	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG3211_4027	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG3211_4028	COG0542	response to heat
LG3211_4036	COG0564	pseudouridine synthase activity
LG3211_4037	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LG3211_4042	COG0045	succinate-CoA ligase (ADP-forming) activity
LG3211_4046	COG4969	Belongs to the N-Me-Phe pilin family
LG3211_4053	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG3211_4054	COG0300	oxidoreductase activity
LG3211_4055	COG0277	FAD linked oxidase domain protein
LG3211_4056	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LG3211_4056	COG0546	phosphoglycolate phosphatase activity
LG3211_4059	COG4106	trans-aconitate 2-methyltransferase activity
LG3211_4061	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LG3211_4063	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LG3211_4064	COG0237	dephospho-CoA kinase activity
LG3211_4065	COG0352	thiamine-phosphate diphosphorylase activity
LG3211_4066	COG0653	protein targeting
LG3211_4067	COG0739	heme binding
LG3211_4073	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LG3211_4074	COG1181	Belongs to the D-alanine--D-alanine ligase family
LG3211_4075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LG3211_4080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LG3211_4081	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LG3211_4083	COG3116	cell division
LG3211_4084	COG0275	rRNA processing
LG3211_4085	COG2001	Belongs to the MraZ family
LG3211_4091	COG1988	membrane-bound metal-dependent
LG3211_4092	COG0277	FAD linked oxidase domain protein
LG3211_4094	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LG3211_4095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG3211_4096	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LG3211_4100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG3211_4100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG3211_4103	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LG3211_4106	COG0488	(ABC) transporter
LG3211_4108	COG0024	Methionine aminopeptidase
LG3211_4109	COG0284	orotidine-5'-phosphate decarboxylase activity
LG3211_4115	COG1450	Type ii and iii secretion system protein
LG3211_4118	COG3166	PFAM Fimbrial assembly family protein
LG3211_4119	COG3156	type II secretion system protein K
LG3211_4120	COG4795	General secretion pathway protein
LG3211_4121	COG2165	general secretion pathway protein
LG3211_4122	COG4970	Tfp pilus assembly protein FimT
LG3211_4123	COG2165	general secretion pathway protein
LG3211_4124	COG1459	type II secretion system
LG3211_4126	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LG3211_4127	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG3211_4127	COG0047	phosphoribosylformylglycinamidine synthase activity
LG3211_4128	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG3211_4129	COG4974	Belongs to the 'phage' integrase family
LG3211_4134	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LG3211_4144	COG1183	phosphatidylcholine synthase activity
LG3211_4146	COG0442	prolyl-tRNA aminoacylation
LG3211_4149	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LG3211_4151	COG1127	ABC transporter
LG3211_4153	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LG3211_4153	COG3218	ABC-type transport auxiliary lipoprotein component
LG3211_4161	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG3211_4170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG3211_4171	COG0463	Glycosyl transferase, family 2
LG3211_4174	COG0494	nUDIX hydrolase
LG3211_4179	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG3211_4180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LG3211_4182	COG2226	methyltransferase
LG3211_4190	COG0626	cystathionine gamma-synthase activity
LG3211_4197	COG0625	glutathione transferase activity
LG3211_4201	COG2815	serine threonine protein kinase
LG3211_4201	COG0515	serine threonine protein kinase
LG3211_4203	COG0456	acetyltransferase
LG3211_4206	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LG3211_4209	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LG3211_4210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LG3211_4214	COG0189	ligase activity
LG3211_4214	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LG3211_4216	COG4242	Belongs to the peptidase S51 family
LG3211_4217	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LG3211_4218	COG2329	Antibiotic biosynthesis monooxygenase
LG3211_4219	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LG3211_4226	COG1597	lipid kinase activity
LG3211_4227	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LG3211_4229	COG0484	heat shock protein binding
LG3211_4230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LG3211_4236	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LG3211_4237	COG0530	calcium, potassium:sodium antiporter activity
LG3211_4244	COG3104	oligopeptide transport
LG3211_4245	COG3483	tryptophan 2,3-dioxygenase activity
LG3211_4249	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LG3211_4253	COG4991	sh3 domain protein
LG3211_4254	COG4991	sh3 domain protein
LG3211_4259	COG0180	Tryptophanyl-tRNA synthetase
LG3211_4261	COG3237	CsbD-like
LG3211_4268	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LG3211_4270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LG3211_4271	COG1307	EDD domain protein, DegV family
LG3211_4273	COG3228	Belongs to the MtfA family
LG3211_4274	COG3290	protein histidine kinase activity
LG3211_4275	COG0745	RESPONSE REGULATOR receiver
LG3211_4278	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG3211_4286	COG0430	RNA-3'-phosphate cyclase activity
LG3211_4287	COG1690	Belongs to the RtcB family
LG3211_4289	COG4650	regulator
LG3211_4291	COG5265	(ABC) transporter
LG3211_4293	COG1214	PFAM Peptidase M22, glycoprotease
LG3211_4293	COG0456	acetyltransferase
LG3211_4305	COG2133	pyrroloquinoline quinone binding
LG3211_4306	COG0741	lytic transglycosylase activity
LG3211_4308	COG0531	amino acid
LG3211_4310	COG3023	N-Acetylmuramoyl-L-alanine amidase
LG3211_4322	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LG3211_4324	COG3795	YCII-related domain
LG3211_4326	COG4989	oxidoreductase activity
LG3211_4335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG3211_4336	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LG3211_4345	COG1522	sequence-specific DNA binding
LG3211_4347	COG0583	DNA-binding transcription factor activity
LG3211_4368	COG1401	restriction endodeoxyribonuclease activity
LG3211_4369	COG0583	DNA-binding transcription factor activity
LG3211_4378	COG1960	acyl-CoA dehydrogenase activity
LG3211_4382	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_4383	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_4384	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LG3211_4384	COG2755	lipolytic protein G-D-S-L family
LG3211_4388	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG3211_4397	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LG3211_4404	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG3211_4411	COG1011	Hydrolase
LG3211_4412	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LG3211_4419	COG1136	(ABC) transporter
LG3211_4420	COG1136	(ABC) transporter
LG3211_4420	COG0577	efflux transmembrane transporter activity
LG3211_4425	COG0697	spore germination
LG3211_4427	COG1522	sequence-specific DNA binding
LG3211_4428	COG2169	Transcriptional regulator
LG3211_4428	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG3211_4431	COG0321	lipoyl(octanoyl) transferase activity
LG3211_4432	COG2921	Belongs to the UPF0250 family
LG3211_4438	COG1686	Belongs to the peptidase S11 family
LG3211_4440	COG2951	lytic endotransglycosylase activity
LG3211_4442	COG3708	Transcriptional regulator
LG3211_4442	COG2207	Transcriptional regulator
LG3211_4445	COG3227	Zinc metalloprotease (Elastase)
LG3211_4456	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG3211_4459	COG0772	Belongs to the SEDS family
LG3211_4460	COG0768	penicillin binding
LG3211_4461	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LG3211_4462	COG1792	Involved in formation and maintenance of cell shape
LG3211_4463	COG1077	Cell shape determining protein MreB Mrl
LG3211_4469	COG0308	aminopeptidase N
LG3211_4471	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_4472	COG2226	methyltransferase
LG3211_4475	COG0456	acetyltransferase
LG3211_4475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG3211_4482	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LG3211_4484	COG2832	Protein of unknown function (DUF454)
LG3211_4486	COG1505	serine-type exopeptidase activity
LG3211_4493	COG0243	molybdopterin cofactor binding
LG3211_4495	COG0437	4 iron, 4 sulfur cluster binding
LG3211_4496	COG3302	dmso reductase anchor subunit
LG3211_4498	COG0181	hydroxymethylbilane synthase activity
LG3211_4500	COG2972	Histidine kinase
LG3211_4500	COG0745	RESPONSE REGULATOR receiver
LG3211_4511	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LG3211_4514	COG0583	DNA-binding transcription factor activity
LG3211_4515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG3211_4516	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LG3211_4518	COG0346	lactoylglutathione lyase activity
LG3211_4523	COG4585	Histidine kinase
LG3211_4524	COG2311	Membrane
LG3211_4534	COG4774	siderophore transport
LG3211_4537	COG1764	response to oxidative stress
LG3211_4538	COG1846	Transcriptional regulator
LG3211_4540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG3211_4542	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG3211_4546	COG4948	Mandelate Racemase Muconate Lactonizing
LG3211_4547	COG1737	Transcriptional regulator
LG3211_4551	COG0006	proline dipeptidase activity
LG3211_4553	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG3211_4556	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG3211_4557	COG3938	Belongs to the proline racemase family
LG3211_4566	COG0673	inositol 2-dehydrogenase activity
LG3211_4571	COG1737	Transcriptional regulator
LG3211_4572	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LG3211_4573	COG3734	2-keto-3-deoxy-galactonokinase
LG3211_4574	COG0800	Aldolase
LG3211_4579	COG1987	bacterial-type flagellum assembly
LG3211_4582	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LG3211_4583	COG4787	bacterial-type flagellum-dependent cell motility
LG3211_4584	COG4786	Flagellar basal body rod
LG3211_4587	COG1706	bacterial-type flagellum-dependent cell motility
LG3211_4590	COG1677	Flagellar hook-basal body complex protein FliE
LG3211_4591	COG1766	The M ring may be actively involved in energy transduction
LG3211_4594	COG1157	protein secretion by the type III secretion system
LG3211_4597	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LG3211_4600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG3211_4600	COG1776	CheC inhibitor of MCP methylation
LG3211_4610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG3211_4613	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG3211_4614	COG0583	DNA-binding transcription factor activity
LG3211_4616	COG2264	protein methyltransferase activity
LG3211_4621	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LG3211_4624	COG1609	Transcriptional regulator
LG3211_4626	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LG3211_4627	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_4633	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LG3211_4634	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LG3211_4637	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LG3211_4640	COG1063	alcohol dehydrogenase
LG3211_4644	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG3211_4651	COG0596	Alpha beta hydrolase
LG3211_4652	COG4771	TonB-dependent receptor
LG3211_4657	COG1073	alpha beta
LG3211_4660	COG1090	epimerase
LG3211_4662	COG1187	pseudouridine synthase activity
LG3211_4666	COG0583	DNA-binding transcription factor activity
LG3211_4668	COG2205	protein histidine kinase activity
LG3211_4676	COG1695	Transcriptional regulator
LG3211_4677	COG0583	DNA-binding transcription factor activity
LG3211_4678	COG1741	Belongs to the pirin family
LG3211_4680	COG0583	DNA-binding transcription factor activity
LG3211_4685	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_4694	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LG3211_4695	COG2011	ABC-type metal ion transport system permease component
LG3211_4703	COG2885	chlorophyll binding
LG3211_4708	COG0577	efflux transmembrane transporter activity
LG3211_4709	COG0577	efflux transmembrane transporter activity
LG3211_4710	COG1136	(ABC) transporter
LG3211_4711	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_4723	COG3590	peptidase
LG3211_4739	COG5295	Hep Hag repeat protein
LG3211_4739	COG5295	Hep Hag repeat protein
LG3211_4743	COG0745	RESPONSE REGULATOR receiver
LG3211_4750	COG1169	isochorismate synthase
LG3211_4752	COG2885	chlorophyll binding
LG3211_4752	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LG3211_4756	COG1609	Transcriptional regulator
LG3211_4757	COG4771	TonB-dependent receptor
LG3211_4758	COG1472	Belongs to the glycosyl hydrolase 3 family
LG3211_4759	COG1609	Transcriptional regulator
LG3211_4761	COG2211	Major facilitator Superfamily
LG3211_4762	COG0673	inositol 2-dehydrogenase activity
LG3211_4779	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG3211_4806	COG4948	Mandelate Racemase Muconate Lactonizing
LG3211_4807	COG1501	Belongs to the glycosyl hydrolase 31 family
LG3211_4809	COG2801	Transposase and inactivated derivatives
LG3211_4810	COG2963	transposase activity
LG3211_4815	COG2972	Histidine kinase
LG3211_4815	COG0745	RESPONSE REGULATOR receiver
LG3211_4816	COG3279	Response regulator of the LytR AlgR family
LG3211_4831	COG1845	cytochrome c oxidase, subunit III
LG3211_4832	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG3211_4833	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG3211_4835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG3211_4838	COG4772	TonB-dependent receptor
LG3211_4840	COG1294	oxidase, subunit
LG3211_4841	COG4993	Dehydrogenase
LG3211_4845	COG0535	radical SAM domain protein
LG3211_4847	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LG3211_4849	COG4993	Dehydrogenase
LG3211_4850	COG2801	Transposase and inactivated derivatives
LG3211_4851	COG2963	transposase activity
LG3211_4857	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LG3211_4893	COG0863	Belongs to the N(4) N(6)-methyltransferase family
LG3211_4916	COG3537	Alpha-1,2-mannosidase
LG3211_4917	COG1609	Transcriptional regulator
LG3211_4919	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG3211_4926	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LG3211_4927	COG1490	D-aminoacyl-tRNA deacylase activity
LG3211_4934	COG3307	-O-antigen
LG3211_4935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LG3211_4936	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG3211_4936	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LG3211_4938	COG0242	peptide deformylase activity
LG3211_4940	COG0758	DNA mediated transformation
LG3211_4941	COG2922	Belongs to the Smg family
LG3211_4942	COG4969	Belongs to the N-Me-Phe pilin family
LG3211_4950	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_4952	COG0616	signal peptide processing
LG3211_4954	COG0534	Mate efflux family protein
LG3211_4959	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LG3211_4964	COG1252	NADH dehydrogenase
LG3211_4972	COG0625	glutathione transferase activity
LG3211_4973	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG3211_4978	COG2267	carboxylic ester hydrolase activity
LG3211_4980	COG0745	RESPONSE REGULATOR receiver
LG3211_4981	COG2205	protein histidine kinase activity
LG3211_4985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG3211_4988	COG2194	sulfuric ester hydrolase activity
LG3211_4990	COG0745	RESPONSE REGULATOR receiver
LG3211_4996	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG3211_4997	COG0583	DNA-binding transcription factor activity
LG3211_4999	COG0583	DNA-binding transcription factor activity
LG3211_5004	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LG3211_5005	COG2201	protein-glutamate methylesterase activity
LG3211_5006	COG2177	Part of the ABC transporter FtsEX involved in
LG3211_5007	COG2884	Cell division ATP-binding protein ftsE
LG3211_5011	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LG3211_5017	COG3100	YcgL domain-containing protein
LG3211_5022	COG1294	oxidase, subunit
LG3211_5023	COG1271	oxidase subunit
LG3211_5025	COG0408	coproporphyrinogen oxidase activity
LG3211_5035	COG0210	DNA helicase
LG3211_5039	COG0625	glutathione transferase activity
LG3211_5049	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG3211_5051	COG0463	Glycosyl transferase, family 2
LG3211_5054	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_5060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LG3211_5070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG3211_5071	COG1959	2 iron, 2 sulfur cluster binding
LG3211_5074	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LG3211_5076	COG4208	sulfate ABC transporter
LG3211_5091	COG0714	Associated with various cellular activities
LG3211_5097	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LG3211_5108	COG0357	Ribosomal RNA small subunit methyltransferase G
LG3211_5109	COG1192	Involved in chromosome partitioning
LG3211_5110	COG1475	DNA binding
LG3211_5114	COG0463	Glycosyl transferase, family 2
LG3211_5117	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LG3211_5118	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG3211_5132	COG1573	uracil-dna glycosylase
LG3211_5133	COG2860	membrane
LG3211_5145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LG3211_5148	COG2815	serine threonine protein kinase
LG3211_5148	COG0515	serine threonine protein kinase
LG3211_5154	COG2911	Protein conserved in bacteria
LG3211_5155	COG0729	surface antigen
LG3211_5156	COG4771	TonB-dependent receptor
LG3211_5158	COG4771	TonB-dependent receptor
LG3211_5161	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG3211_5161	COG0519	Catalyzes the synthesis of GMP from XMP
LG3211_5165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LG3211_5166	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LG3211_5170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LG3211_5171	COG0596	Alpha beta hydrolase
LG3211_5174	COG0037	tRNA processing
LG3211_5181	COG2937	Belongs to the GPAT DAPAT family
LG3211_5189	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LG3211_5197	COG0210	DNA helicase
LG3211_5201	COG3541	Predicted nucleotidyltransferase
LG3211_5203	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LG3211_5205	COG0443	Heat shock 70 kDa protein
LG3211_5206	COG1205	dead DEAH box helicase
LG3211_5206	COG1111	helicase
LG3211_5216	COG0070	glutamate synthase
LG3211_5216	COG0069	glutamate synthase activity
LG3211_5216	COG0067	glutamate synthase
LG3211_5218	COG0493	'glutamate synthase
LG3211_5219	COG0302	gtp cyclohydrolase
LG3211_5221	COG2199	diguanylate cyclase activity
LG3211_5222	COG0697	spore germination
LG3211_5226	COG0156	8-amino-7-oxononanoate synthase activity
LG3211_5227	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LG3211_5228	COG1040	competence protein
LG3211_5232	COG2031	fatty acid transporter
LG3211_5238	COG2963	transposase activity
LG3211_5239	COG2801	Transposase and inactivated derivatives
LG3211_5244	COG4977	sequence-specific DNA binding
LG3211_5245	COG1028	Short-chain dehydrogenase reductase Sdr
LG3211_5248	COG0071	Belongs to the small heat shock protein (HSP20) family
LG3211_5253	COG0583	DNA-binding transcription factor activity
LG3211_5264	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LG3211_5265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LG3211_5267	COG0384	phenazine biosynthesis protein PhzF
LG3211_5269	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG3211_5273	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG3211_5288	COG2936	dipeptidyl-peptidase activity
LG3211_5298	COG3275	phosphorelay sensor kinase activity
LG3211_5299	COG3279	Response regulator of the LytR AlgR family
LG3211_5304	COG0754	glutathionylspermidine amidase activity
LG3211_5306	COG3766	membrane
LG3211_5309	COG1842	Phage shock protein A
LG3211_5315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LG3211_5320	COG1538	Outer membrane efflux protein
LG3211_5326	COG0667	Aldo Keto reductase
LG3211_5328	COG1473	amidohydrolase
LG3211_5332	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LG3211_5332	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LG3211_5333	COG1652	LysM domain
LG3211_5335	COG3012	SEC-C Motif Domain Protein
LG3211_5336	COG3012	SEC-C Motif Domain Protein
LG3211_5336	COG3318	Belongs to the UPF0149 family
LG3211_5340	COG0538	isocitrate dehydrogenase activity
LG3211_5346	COG0583	DNA-binding transcription factor activity
LG3211_5348	COG1187	pseudouridine synthase activity
LG3211_5352	COG0667	Aldo Keto reductase
LG3211_5353	COG0745	RESPONSE REGULATOR receiver
LG3211_5353	COG3706	GGDEF domain
LG3211_5355	COG1643	Atp-dependent helicase
LG3211_5357	COG0084	hydrolase, TatD family'
LG3211_5361	COG0842	Transport permease protein
LG3211_5362	COG1131	(ABC) transporter
LG3211_5366	COG4555	ABC transporter
LG3211_5367	COG1668	transmembrane transport
LG3211_5369	COG4260	virion core protein, lumpy skin disease virus
LG3211_5372	COG2814	Major facilitator Superfamily
LG3211_5375	COG1902	pentaerythritol trinitrate reductase activity
LG3211_5378	COG0706	membrane insertase activity
LG3211_5379	COG0594	ribonuclease P activity