locus-tag	class	description
A4G16_00005	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A4G16_00010	ENOG4105CD8	aminopeptidase N
A4G16_00015	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4G16_00020	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A4G16_00025	ENOG4105HSA	Protein of unknown function (DUF452)
A4G16_00030	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4G16_00035	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4G16_00040	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
A4G16_00055	ENOG4105E0U	tyrosine-specific transport protein
A4G16_00060	ENOG4108JA2	transcriptioN-repair coupling factor
A4G16_00075	ENOG41067QW	Transcriptional regulator
A4G16_00080	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A4G16_00115	ENOG4107SRH	Nad-dependent epimerase dehydratase
A4G16_00120	ENOG4105CC5	ABC transporter
A4G16_00125	ENOG4105CC5	ABC transporter
A4G16_00130	ENOG4105DIK	(ABC) transporter
A4G16_00160	ENOG41090FY	type IV pilus biogenesis stability protein PilW
A4G16_00165	ENOG4105BZM	domain protein
A4G16_00170	ENOG4105E1F	short-chain dehydrogenase reductase
A4G16_00175	ENOG41069NU	Nitroreductase
A4G16_00180	ENOG4105D07	Signal peptide peptidase, SppA
A4G16_00200	ENOG4105CSH	Transporter
A4G16_00205	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
A4G16_00220	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A4G16_00230	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
A4G16_00235	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
A4G16_00240	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A4G16_00245	ENOG4105DVI	reductase, NrfD
A4G16_00250	ENOG4105DA4	cytochrome c-type biogenesis protein
A4G16_00255	ENOG4107QX9	Thiol disulfide interChange protein
A4G16_00260	ENOG4108DMF	Cytochrome C biogenesis protein
A4G16_00265	ENOG4108DMF	Cytochrome C biogenesis protein
A4G16_00270	ENOG4105C0H	protease
A4G16_00275	ENOG4105DHJ	ABC, transporter
A4G16_00280	ENOG4105CY3	ABC transporter, permease
A4G16_00285	ENOG4107PE3	Mammalian cell entry related domain protein
A4G16_00290	ENOG4105E3I	toluene tolerance
A4G16_00300	ENOG4105VFK	BolA family
A4G16_00305	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4G16_00310	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A4G16_00320	ENOG4105CDY	transcriptional regulatory protein
A4G16_00325	ENOG4108TIT	dATP pyrophosphohydrolase
A4G16_00335	ENOG4105EHG	Permease protein
A4G16_00340	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A4G16_00345	ENOG41063SR	receptor
A4G16_00370	ENOG4105DWU	Membrane
A4G16_00380	ENOG4105D0M	Protease HtpX homolog
A4G16_00385	ENOG4105W39	Membrane
A4G16_00390	ENOG4105TMB	Formate nitrite transporter
A4G16_00395	ENOG4105C6N	Formate acetyltransferase
A4G16_00410	ENOG4105F1A	Pyruvate formate-lyase
A4G16_00415	ENOG4105DGW	oligopeptidase A
A4G16_00420	ENOG4105D5K	Hemolysin activator protein
A4G16_00480	ENOG4105CQC	Prephenate dehydratase
A4G16_00485	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A4G16_00490	ENOG4107T0K	Adenylate cyclase
A4G16_00495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4G16_00500	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4G16_00505	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4G16_00510	ENOG4105EIB	trna rrna methyltransferase
A4G16_00515	ENOG4105ECY	inositol monophosphatase
A4G16_00520	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A4G16_00530	ENOG4105EYA	deoxyribonuclease
A4G16_00545	ENOG4105M15	transport protein ExbD
A4G16_00550	ENOG4105M8K	biopolymer transport protein
A4G16_00560	ENOG4107QR8	Thioredoxin
A4G16_00565	ENOG4105VDH	Dihydroxyacetone kinase
A4G16_00570	ENOG4108UTZ	Dihydroxyacetone kinase
A4G16_00575	ENOG4105CMT	Dihydroxyacetone kinase
A4G16_00580	ENOG4105C3M	thioredoxin reductase
A4G16_00585	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A4G16_00600	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A4G16_00605	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A4G16_00610	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4G16_00615	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A4G16_00635	ENOG4108V5Q	transglutaminase-like protein
A4G16_00640	ENOG4105DDQ	anthranilate synthase
A4G16_00645	ENOG4105CRQ	synthase (Component I)
A4G16_00650	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A4G16_00655	ENOG4105FE9	pseudouridine synthase
A4G16_00665	ENOG4105D60	lipoprotein releasing system transmembrane protein
A4G16_00670	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4G16_00675	ENOG4105D60	lipoprotein releasing system transmembrane protein
A4G16_00685	ENOG41063JG	Transcriptional regulator
A4G16_00690	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4G16_00705	ENOG4105DDQ	anthranilate synthase
A4G16_00710	ENOG4105CGY	Dna recombination protein
A4G16_00715	ENOG4105CRQ	synthase (Component I)
A4G16_00725	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A4G16_00730	ENOG4105Y3E	Modulates RecA activity (By similarity)
A4G16_00735	ENOG41060QA	UPF0267 protein
A4G16_00740	ENOG4108WI1	Dna topoisomerase
A4G16_00745	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4G16_00750	ENOG4105E2X	shikimate dehydrogenase
A4G16_00775	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A4G16_00790	ENOG4105EHG	Permease protein
A4G16_00800	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A4G16_00805	ENOG4105SYT	Methylenetetrahydrofolate reductase
A4G16_00810	ENOG4105CMR	udp-glucose 4-epimerase
A4G16_00815	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4G16_00835	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
A4G16_00885	ENOG41067QW	Transcriptional regulator
A4G16_00905	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A4G16_00910	ENOG4105C12	Phosphoribosylglycinamide synthetase
A4G16_00925	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A4G16_00930	ENOG4107RZZ	dna polymerase iii epsilon subunit
A4G16_00935	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G16_00945	ENOG4107QKW	extracellular solute-binding protein family 1
A4G16_00950	ENOG4105C5H	ABC transporter
A4G16_00955	ENOG4105DGN	Electron transport complex
A4G16_00960	ENOG4108R3D	Electron transport complex
A4G16_00965	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
A4G16_00970	ENOG4105EN6	Membrane
A4G16_00975	ENOG4105D6A	Electron transport complex
A4G16_00990	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A4G16_00995	ENOG4105CIN	aminoacyl-histidine dipeptidase
A4G16_01000	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A4G16_01005	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A4G16_01010	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A4G16_01020	ENOG4105DP9	ABC transporter
A4G16_01025	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A4G16_01030	ENOG4105DJ0	Poly(A) Polymerase
A4G16_01035	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4G16_01055	ENOG4108UYE	Lactoylglutathione lyase
A4G16_01060	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A4G16_01065	ENOG4105C44	Serine transporter
A4G16_01070	ENOG4105EJQ	L-serine dehydratase
A4G16_01075	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A4G16_01080	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A4G16_01085	ENOG4108BY2	phosphohistidine phosphatase
A4G16_01090	ENOG4105CA9	Pyruvate kinase
A4G16_01095	ENOG4105DKP	glycosyl transferase, family 9
A4G16_01100	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4G16_01105	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
A4G16_01115	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4G16_01120	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A4G16_01125	ENOG4105M2J	Glutaredoxin
A4G16_01130	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4G16_01140	ENOG4105M4H	endoribonuclease L-psp
A4G16_01145	ENOG4108BPE	-transporting atpase
A4G16_01150	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A4G16_01155	ENOG4105E5Z	arginine transporter ATP-binding subunit
A4G16_01160	ENOG4106PMH	Extracellular solute-binding protein family 3
A4G16_01165	ENOG4105GBT	ABC transporter
A4G16_01170	ENOG4105DMR	ABC, transporter
A4G16_01175	ENOG4105D38	putrescine abc transporter
A4G16_01180	ENOG4105F38	ABC transporter, permease
A4G16_01185	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G16_01190	ENOG4105C4R	Atp-dependent dna helicase
A4G16_01195	ENOG4108IJ0	Aspartate ammonia-lyase
A4G16_01200	ENOG410696E	Membrane
A4G16_01205	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A4G16_01215	ENOG4107UWN	reductase
A4G16_01220	ENOG4105XW2	UPF0263 protein
A4G16_01225	ENOG4106H78	methyltransferase
A4G16_01230	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A4G16_01235	ENOG4105CAK	Cell division ATP-binding protein ftsE
A4G16_01240	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A4G16_01245	ENOG4105DZ2	Transcriptional regulator
A4G16_01250	ENOG41080C8	DUF218 domain
A4G16_01260	ENOG4105D2T	synthase
A4G16_01275	ENOG4108MY6	biosynthesis protein
A4G16_01280	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
A4G16_01285	ENOG41068D6	Glycosyltransferase
A4G16_01295	ENOG4108RJ9	Glycosyl transferase, family 2
A4G16_01300	ENOG4108RYC	glycosyltransferase
A4G16_01305	ENOG4105E0X	reductase
A4G16_01310	ENOG4105D9N	nucleoside
A4G16_01320	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A4G16_01325	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A4G16_01335	ENOG4105C8Y	Acetylornithine aminotransferase
A4G16_01340	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A4G16_01345	ENOG4105C6T	cysteine synthase
A4G16_01350	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A4G16_01355	ENOG4105CFH	Aspartokinase
A4G16_01360	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
A4G16_01385	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A4G16_01390	ENOG4105E98	transcriptional regulator DeoR family
A4G16_01395	ENOG4105E70	isomerase
A4G16_01400	ENOG4108UZY	PTS System
A4G16_01405	ENOG4105ETZ	PTS System
A4G16_01410	ENOG4105F3R	pts system mannose fructose sorbose family iid
A4G16_01430	ENOG4105D2M	Aldolase
A4G16_01435	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4G16_01440	ENOG4107QYX	exodeoxyribonuclease v alpha
A4G16_01475	ENOG4105VG0	50S ribosomal protein l34
A4G16_01480	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A4G16_01485	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A4G16_01500	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
A4G16_01515	ENOG4108RYC	glycosyltransferase
A4G16_01525	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4G16_01530	ENOG4105PF3	O-Antigen polymerase
A4G16_01540	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A4G16_01545	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4G16_01555	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A4G16_01560	ENOG4108R96	Methyltransferase, YaeB family
A4G16_01570	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A4G16_01575	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A4G16_01580	ENOG4105C7B	Threonine dehydratase
A4G16_01585	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A4G16_01590	ENOG4105E66	phosphoriboisomerase A
A4G16_01595	ENOG4108JQ1	Dehydrogenase
A4G16_01605	ENOG41065U4	response regulator
A4G16_01610	ENOG4108VVQ	metallophosphoesterase
A4G16_01615	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
A4G16_01620	ENOG4105DTN	riboflavin biosynthesis protein ribF
A4G16_01625	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A4G16_01640	ENOG4105JIM	Phosphatidylserine synthase
A4G16_01645	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4G16_01650	ENOG4108JQ5	ABC transporter
A4G16_01655	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G16_01660	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4G16_01665	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G16_01685	ENOG41061WM	D-Alanyl-D-Alanine
A4G16_01690	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A4G16_01695	ENOG4105C3G	gtp-binding protein
A4G16_01700	ENOG4105DAA	L-lactate
A4G16_01705	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A4G16_01710	ENOG4107QR9	Iron-sulfur cluster binding protein
A4G16_01715	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
A4G16_01720	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A4G16_01725	ENOG4105DSJ	YicC domain protein
A4G16_01730	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A4G16_01735	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A4G16_01745	ENOG4105CNN	ABC, transporter
A4G16_01750	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A4G16_01755	ENOG4108RVA	ribokinase
A4G16_01760	ENOG4105ETE	Transcriptional regulator (LacI family
A4G16_01765	ENOG4105WH1	Two component transcriptional regulator luxr family
A4G16_01775	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A4G16_01780	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A4G16_01785	ENOG4105CE4	GlcNAc 6-P deacetylase
A4G16_01795	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A4G16_01825	ENOG4108RE7	deoxyribonuclease
A4G16_01835	ENOG4108NRW	Phospholipase, patatin family
A4G16_01845	ENOG41083KI	ribonuclease, T2
A4G16_01850	ENOG4105GPY	SprT protein
A4G16_01855	ENOG4105CEP	NADH dehydrogenase
A4G16_01860	ENOG4105C4Y	ABC transporter
A4G16_01865	ENOG4105C7N	Xanthine uracil vitamin C permease
A4G16_01870	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4G16_01875	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4G16_01880	ENOG4105VIE	preprotein translocase, subunit YajC
A4G16_01885	ENOG4108UUE	Transcriptional regulator
A4G16_01890	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A4G16_01900	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A4G16_01905	ENOG4105DIN	metallophosphoesterase
A4G16_01920	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
A4G16_01930	ENOG4105D0A	hydroxylase
A4G16_01935	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A4G16_01940	ENOG4105EUJ	GTP cyclohydrolase i
A4G16_01950	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G16_01955	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A4G16_01960	ENOG4107ZVW	dihydroneopterin aldolase
A4G16_01965	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
A4G16_01975	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4G16_01980	ENOG4109045	doxx family
A4G16_01990	ENOG4105E18	UPF0276 protein
A4G16_02000	ENOG4108WQI	RNA Polymerase
A4G16_02010	ENOG4105EIF	outer membrane protein W
A4G16_02025	ENOG4105C01	Dihydroxy-acid dehydratase
A4G16_02035	ENOG4105D2S	major facilitator superfamily
A4G16_02045	ENOG4108Z1B	Cyclase dehydrase
A4G16_02050	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A4G16_02055	ENOG4105E0C	molybdate abc transporter
A4G16_02060	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A4G16_02065	ENOG4105E3A	(ABC) transporter
A4G16_02070	ENOG4105DA5	(ABC) transporter
A4G16_02075	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A4G16_02080	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A4G16_02085	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A4G16_02090	ENOG4108MN8	Membrane
A4G16_02095	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A4G16_02125	ENOG4105K63	Thioredoxin
A4G16_02130	ENOG4107QJR	hflk protein
A4G16_02135	ENOG4105EPW	hflc protein
A4G16_02145	ENOG4105CY2	Citrate transporter
A4G16_02155	ENOG4105CHU	acetyl-coa acetyltransferase
A4G16_02160	ENOG4105CRW	Short chain fatty acid transporter
A4G16_02165	ENOG4107QNJ	CoA-transferase subunit B
A4G16_02170	ENOG4107QP7	CoA-transferase subunit A
A4G16_02175	ENOG4105CMU	LysR family (Transcriptional regulator
A4G16_02290	ENOG4105CAR	Terminase, large subunit
A4G16_02355	ENOG4108MXB	Protein of unknown function (DUF968)
A4G16_02370	ENOG4105W7J	DNA binding
A4G16_02390	ENOG4105YES	addiction module antidote protein
A4G16_02395	ENOG4105VUH	addiction module killer protein
A4G16_02415	ENOG4108UUM	single-stranded DNA-binding protein
A4G16_02420	ENOG4105H40	
A4G16_02440	ENOG4108KU3	Integrase
A4G16_02455	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A4G16_02465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G16_02475	ENOG4105F38	ABC transporter, permease
A4G16_02480	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
A4G16_02620	ENOG4105CF2	Mu-like prophage FluMu protein GP28
A4G16_02735	ENOG4105ZIA	Phage protein gp16
A4G16_02745	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A4G16_02750	ENOG4108MVK	Receptor
A4G16_02755	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A4G16_02760	ENOG4105D1S	lipid A biosynthesis
A4G16_02765	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4G16_02770	ENOG4105C5H	ABC transporter
A4G16_02775	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A4G16_02780	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A4G16_02785	ENOG4105D06	uba thif-type nad fad binding protein
A4G16_02795	ENOG4105PQ6	UPF0208 membrane protein
A4G16_02805	ENOG4107835	probably involved in intracellular septation (By similarity)
A4G16_02810	ENOG4105NAU	thioesterase Superfamily protein
A4G16_02815	ENOG4105K9H	YciI-like protein
A4G16_02820	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A4G16_02830	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A4G16_02835	ENOG4105XCT	Protein of unknown function (DUF2489)
A4G16_02840	ENOG4105D4P	Coproporphyrinogen iii oxidase
A4G16_02845	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A4G16_02850	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A4G16_02870	ENOG4108V0P	LemA family
A4G16_02875	ENOG4105DM4	PTS System
A4G16_02880	ENOG4105DE4	1-phosphofructokinase
A4G16_02885	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A4G16_02895	ENOG4108ESZ	Glycogen debranching enzyme
A4G16_02900	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A4G16_02905	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A4G16_02910	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A4G16_02915	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A4G16_02920	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4G16_02925	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4G16_02935	ENOG4105DHP	deoxycytidine triphosphate deaminase
A4G16_02940	ENOG4105DBI	uridine monophosphokinase
A4G16_02945	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A4G16_02950	ENOG4105DFF	Rod shape-determining protein mreb
A4G16_02955	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A4G16_02965	ENOG4105D1H	recombination factor protein RarA
A4G16_02970	ENOG4105FAV	ABC, transporter
A4G16_02975	ENOG4105E7A	Glutamine amidotransferase
A4G16_02985	ENOG4105CQ0	ABC transporter
A4G16_02990	ENOG4105CTB	Polyprenyl synthetase
A4G16_03000	ENOG4105QVC	MOSC domain-containing protein
A4G16_03005	ENOG4105E0M	Sulfatase
A4G16_03015	ENOG4105EYK	Phosphatidylglycerophosphatase B
A4G16_03020	ENOG4105HBR	Rna-binding protein
A4G16_03025	ENOG4106WTF	Glycosyl transferase, family 2
A4G16_03030	ENOG4105M5K	heptosyltransferase
A4G16_03040	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4G16_03045	ENOG4105E96	Colicin v production protein
A4G16_03050	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A4G16_03060	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A4G16_03080	ENOG4105N16	Protein of unknown function (DUF2877)
A4G16_03085	ENOG4105CD3	dihydroorotase
A4G16_03090	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A4G16_03100	ENOG4105S0E	allantoin catabolism protein
A4G16_03105	ENOG4105DG4	malate L-lactate dehydrogenase
A4G16_03110	ENOG4107REC	cytoplasmic protein
A4G16_03115	ENOG4105C5B	carbamate kinase
A4G16_03120	ENOG4105DAA	L-lactate
A4G16_03130	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A4G16_03135	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
A4G16_03145	ENOG4105C5R	Aminotransferase
A4G16_03150	ENOG4105CF7	AraC family transcriptional regulator
A4G16_03160	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A4G16_03165	ENOG4105CH2	amidohydrolase
A4G16_03175	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
A4G16_03180	ENOG4105BZU	Histidine kinase
A4G16_03185	ENOG4108YZA	Nitrogen regulatory protein pii
A4G16_03190	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A4G16_03205	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A4G16_03210	ENOG4105C3F	Signal peptidase i
A4G16_03220	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A4G16_03225	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A4G16_03300	ENOG4105C1J	atp-dependent rna helicase
A4G16_03310	ENOG4105D7A	ATP-binding protein
A4G16_03320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A4G16_03325	ENOG4108I6E	Sulfatase
A4G16_03330	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A4G16_03335	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A4G16_03340	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4G16_03345	ENOG41063SB	peptidase
A4G16_03350	ENOG4105PXI	polysaccharide deacetylase
A4G16_03355	ENOG4105CFU	surface antigen
A4G16_03360	ENOG4105MA0	exported protein
A4G16_03365	ENOG4108JJ9	ABC, transporter
A4G16_03370	ENOG4108JJ8	(ABC) transporter
A4G16_03375	ENOG41075W9	High frequency lysogenization protein HflD homolog
A4G16_03380	ENOG4107QTF	adenylosuccinate lyase
A4G16_03385	ENOG4105E98	transcriptional regulator DeoR family
A4G16_03390	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A4G16_03395	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G16_03400	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A4G16_03410	ENOG4108K4B	hydrolase
A4G16_03415	ENOG4105BZU	Histidine kinase
A4G16_03425	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A4G16_03430	ENOG4105K8R	UPF0145 protein
A4G16_03435	ENOG4108ZZ3	UPF0260 protein
A4G16_03440	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4G16_03445	ENOG4108JU8	Transcriptional regulator
A4G16_03450	ENOG4108EVY	peptide transport periplasmic protein
A4G16_03460	ENOG4108EU3	peptide transport system, permease
A4G16_03465	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A4G16_03490	ENOG4105E0X	reductase
A4G16_03495	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A4G16_03545	ENOG4105CAR	Terminase, large subunit
A4G16_03610	ENOG4105DFP	Integrase
A4G16_03625	ENOG4108IYH	Dna topoisomerase
A4G16_03630	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
A4G16_03635	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A4G16_03640	ENOG4105EGS	Mechanosensitive ion channel
A4G16_03645	ENOG4105CEY	Amp-dependent synthetase and ligase
A4G16_03650	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A4G16_03655	ENOG4105EV9	Alpha Beta Hydrolase
A4G16_03660	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A4G16_03665	ENOG4105ETE	Transcriptional regulator (LacI family
A4G16_03670	ENOG4108VD1	dedA family
A4G16_03680	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A4G16_03690	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4G16_03695	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A4G16_03710	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A4G16_03715	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
A4G16_03745	ENOG4105C03	ribonuclease
A4G16_03750	ENOG4105CRK	lysyL-tRNA synthetase
A4G16_03755	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A4G16_03760	ENOG4105DWV	Homoserine O-trans-acetylase
A4G16_03765	ENOG4107GZ4	SanA protein
A4G16_03770	ENOG4105CIY	formyltetrahydrofolate deformylase
A4G16_03775	ENOG4108X73	DNA- binding protein
A4G16_03780	ENOG4107S6Z	Na H antiporter
A4G16_03785	ENOG4105EMU	Dehydrogenase
A4G16_03800	ENOG4108478	ec 3.2.1.18
A4G16_03810	ENOG4105C2M	dna polymerase I
A4G16_03815	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A4G16_03825	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A4G16_03835	ENOG4105C6K	Malic enzyme
A4G16_03845	ENOG4108UUM	single-stranded DNA-binding protein
A4G16_03850	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4G16_03855	ENOG4105CHH	sulfate transporter
A4G16_03870	ENOG4105DVT	helicase
A4G16_03875	ENOG4105BZ1	(ABC) transporter
A4G16_03885	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A4G16_03890	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A4G16_03895	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A4G16_03900	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A4G16_03905	ENOG4107QSN	dihydrolipoamide acetyltransferase
A4G16_03910	ENOG4107QN2	dihydrolipoyl dehydrogenase
A4G16_03915	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A4G16_03930	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
A4G16_03935	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A4G16_03940	ENOG4108UJD	30S ribosomal protein S9
A4G16_03945	ENOG4105E68	Sulfatase
A4G16_03955	ENOG4105Y7M	Transcriptional regulator, TetR family
A4G16_03960	ENOG410624X	efflux transporter, rnd family, mfp subunit
A4G16_03970	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A4G16_03975	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A4G16_03985	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4G16_03990	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A4G16_04000	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A4G16_04005	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4G16_04015	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A4G16_04025	ENOG4105CJ3	phosphate transporter
A4G16_04030	ENOG4107IX6	phosphate transport regulator
A4G16_04035	ENOG4108IPW	abc transporter atp-binding protein
A4G16_04040	ENOG4105CM4	permease protein
A4G16_04045	ENOG4105DHS	permease protein
A4G16_04055	ENOG4105CDU	Replicative dna helicase
A4G16_04060	ENOG4105VNG	YcgL domain-containing protein
A4G16_04065	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A4G16_04070	ENOG4105D1Q	UPF0246 protein
A4G16_04080	ENOG41076HS	cation diffusion facilitator family transporter
A4G16_04085	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
A4G16_04090	ENOG4107R6U	sodium dicarboxylate symporter
A4G16_04095	ENOG4108RCM	Nitroreductase
A4G16_04100	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A4G16_04105	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A4G16_04110	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4G16_04115	ENOG4108QBX	(LipO)protein
A4G16_04120	ENOG4105C0H	protease
A4G16_04125	ENOG4105CAT	Cytidine monophosphate kinase
A4G16_04130	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A4G16_04135	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4G16_04140	ENOG4105Q4A	inner membrane protein yciS
A4G16_04145	ENOG4105CFV	Tetratricopeptide repeat protein
A4G16_04150	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A4G16_04155	ENOG4108ZJT	translation initiation factor, Sui1
A4G16_04160	ENOG4105CGH	5'-nucleotidase
A4G16_04165	ENOG41080IJ	Diacylglycerol kinase
A4G16_04170	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
A4G16_04175	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A4G16_04185	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A4G16_04190	ENOG4105HDK	L-asparaginase
A4G16_04195	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A4G16_04200	ENOG4107MKT	Stringent starvation protein a
A4G16_04205	ENOG4105KB2	stringent starvation protein b
A4G16_04220	ENOG4105CC0	LysR family Transcriptional regulator
A4G16_04225	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A4G16_04230	ENOG4105CHW	UPF0052 protein
A4G16_04240	ENOG4105DVA	methyltransferase
A4G16_04245	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
A4G16_04260	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4G16_04265	ENOG4105E2R	ROK family
A4G16_04270	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A4G16_04275	ENOG4105EW9	transcriptional regulator AsnC family
A4G16_04280	ENOG4105CNU	cell division protein FtsK
A4G16_04285	ENOG4105CGZ	zinc metallopeptidase
A4G16_04290	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4G16_04295	ENOG41072GX	Peptidase M22 Glycoprotease
A4G16_04300	ENOG4107104	thymidine kinase
A4G16_04310	ENOG4105CBT	Fructose-1,6-bisphosphatase
A4G16_04315	ENOG4107A4G	HTH_XRE
A4G16_04320	ENOG4107RAQ	aminopeptidase
A4G16_04325	ENOG4107EPN	Domain of unknown function (DUF1508)
A4G16_04335	ENOG4108SXK	Transporter Drug Metabolite Exporter family
A4G16_04340	ENOG4108ZP8	Acetolactate synthase small subunit
A4G16_04345	ENOG4105C7K	acetolactate synthase
A4G16_04350	ENOG41077A9	carbonic anhydrase
A4G16_04355	ENOG4108DNC	Involved in acetate metabolism (By similarity)
A4G16_04365	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A4G16_04375	ENOG4105C28	cystathionine
A4G16_04380	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A4G16_04390	ENOG4105M08	Membrane
A4G16_04395	ENOG4107QY8	reductase
A4G16_04400	ENOG4107QIJ	Aconitate hydratase 2
A4G16_04405	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A4G16_04410	ENOG4105BZN	citrate synthase
A4G16_04425	ENOG4107QY8	reductase
A4G16_04430	ENOG4105CUW	cytochrome C-TYPE protein
A4G16_04435	ENOG4106S2D	Transcriptional regulator
A4G16_04445	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4G16_04450	ENOG4105M00	molybdopterin converting factor, subunit 1
A4G16_04455	ENOG4108ZAF	Molybdopterin
A4G16_04460	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A4G16_04465	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A4G16_04470	ENOG4105CGF	Aromatic amino acid aminotransferase
A4G16_04475	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4G16_04485	ENOG4105DXN	mazG family
A4G16_04490	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A4G16_04495	ENOG4105E0F	Histidine kinase
A4G16_04500	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4G16_04505	ENOG4107QNR	UPF0135 protein
A4G16_04510	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4G16_04515	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4G16_04520	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A4G16_04530	ENOG4105DBE	peroxidase
A4G16_04540	ENOG4105DB7	PHP domain protein
A4G16_04550	ENOG4105CJB	Exodeoxyribonuclease I
A4G16_04555	ENOG4105C5S	asparaginyl-tRNA synthetase
A4G16_04560	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A4G16_04570	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A4G16_04580	ENOG4105CX6	glutaminyL-tRNA synthetase
A4G16_04585	ENOG4107R37	Glutamate dehydrogenase
A4G16_04590	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A4G16_04595	ENOG4106V8H	Nucleoid-associated protein
A4G16_04600	ENOG4105KME	endoribonuclease L-psp
A4G16_04605	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A4G16_04625	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A4G16_04630	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A4G16_04635	ENOG4105N42	UPF0307 protein
A4G16_04645	ENOG4108UQV	Membrane
A4G16_04650	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A4G16_04655	ENOG4108ZPB	UPF0306 protein
A4G16_04665	ENOG4105E0K	tonB-dependent siderophore receptor
A4G16_04675	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A4G16_04680	ENOG4105NSG	hemerythrin hhe cation binding domain protein
A4G16_04685	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A4G16_04690	ENOG4105F3T	(LipO)protein
A4G16_04695	ENOG4105VEQ	Cold shock protein
A4G16_04700	ENOG4108P11	EamA-like transporter family
A4G16_04705	ENOG4105QEK	Transcriptional regulator
A4G16_04710	ENOG4108R66	Conserved Protein
A4G16_04715	ENOG4105C9X	ppx gppa phosphatase
A4G16_04720	ENOG41090HJ	UPF0265 protein
A4G16_04725	ENOG4105CFH	Aspartokinase
A4G16_04730	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
A4G16_04735	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A4G16_04745	ENOG4106AFQ	Histidine kinase
A4G16_04765	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G16_04770	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4G16_04775	ENOG4105RT1	May be involved in cell division (By similarity)
A4G16_04780	ENOG4105C1J	atp-dependent rna helicase
A4G16_04785	ENOG4108Z6B	deaminase
A4G16_04790	ENOG4105CVE	Lytic murein transglycosylase
A4G16_04800	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A4G16_04805	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A4G16_04810	ENOG4105CHV	Transcription elongation factor NusA
A4G16_04815	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A4G16_04825	ENOG4107SC1	transglycosylase
A4G16_04830	ENOG4105T95	Thiol disulfide interChange protein
A4G16_04835	ENOG4105DR5	peptidase
A4G16_04840	ENOG4105FDK	ABC transporter
A4G16_04845	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A4G16_04850	ENOG4105C7S	Dehydrogenase
A4G16_04855	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4G16_04860	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A4G16_04865	ENOG4105BZG	amino acid carrier protein
A4G16_04870	ENOG4105D7X	high-affinity nickel-transporter
A4G16_04890	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A4G16_04925	ENOG4105DDY	UPF0142 protein ycaO
A4G16_04945	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A4G16_04955	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A4G16_04960	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A4G16_04980	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4G16_04985	ENOG4105BZU	Histidine kinase
A4G16_04990	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4G16_05000	ENOG4105E2Z	phosphate ABC transporter (Permease
A4G16_05005	ENOG4105C8U	phosphate abc transporter
A4G16_05010	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
A4G16_05015	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A4G16_05020	ENOG4105KNE	Phosphatidate cytidylyltransferase
A4G16_05025	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4G16_05030	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4G16_05040	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G16_05045	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A4G16_05050	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G16_05055	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A4G16_05060	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A4G16_05065	ENOG4105WP7	tRNA pseudouridine synthase C
A4G16_05070	ENOG4105DR9	pseudouridine synthase
A4G16_05080	ENOG4105I7R	Adenylate cyclase
A4G16_05085	ENOG4105CM6	amino acid regulated cytosolic protein
A4G16_05090	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A4G16_05115	ENOG4105C8T	Leucyl-tRNA synthetase
A4G16_05125	ENOG4105DJF	DNA polymerase III, delta' subunit
A4G16_05130	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A4G16_05135	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A4G16_05155	ENOG4105D7Q	type ii secretion system
A4G16_05160	ENOG4107QHF	type ii secretion system protein e
A4G16_05170	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A4G16_05175	ENOG4106CC8	Bacterial inner membrane protein
A4G16_05180	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A4G16_05185	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A4G16_05190	ENOG4105EJ9	Membrane
A4G16_05195	ENOG4105CSM	endonuclease III
A4G16_05200	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A4G16_05205	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A4G16_05210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A4G16_05215	ENOG4105WVQ	Fe-S assembly protein IscX
A4G16_05220	ENOG4108ZIT	Ferredoxin, 2FE-2S
A4G16_05235	ENOG4108RF1	Protein of unknown function DUF2625
A4G16_05245	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A4G16_05250	ENOG4108Z4V	iron-sulfur cluster assembly
A4G16_05255	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A4G16_05260	ENOG4105C3J	Cysteine desulfurase
A4G16_05265	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A4G16_05270	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A4G16_05275	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4G16_05280	ENOG4105BZU	Histidine kinase
A4G16_05290	ENOG4108TZV	Membrane
A4G16_05300	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
A4G16_05305	ENOG4108DG9	Smr protein MutS2
A4G16_05310	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A4G16_05315	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A4G16_05325	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A4G16_05330	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A4G16_05335	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4G16_05345	ENOG4105CSA	Coproporphyrinogen iii oxidase
A4G16_05350	ENOG4107QSI	ABC, transporter
A4G16_05365	ENOG4108JQ6	ABC transporter
A4G16_05370	ENOG4108IYU	L-aspartate oxidase
A4G16_05375	ENOG4105DFD	Na H antiporter
A4G16_05385	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4G16_05400	ENOG4108JJA	ABC, transporter
A4G16_05410	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A4G16_05415	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4G16_05420	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A4G16_05425	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A4G16_05430	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4G16_05435	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A4G16_05440	ENOG4105CEY	Amp-dependent synthetase and ligase
A4G16_05450	ENOG4105VQK	sigma E regulatory protein, MucB RseB
A4G16_05455	ENOG41069PW	sigma-e factor negative regulatory protein
A4G16_05460	ENOG4105EMN	RNA polymerase sigma factor
A4G16_05470	ENOG4105DQF	Hydrolase
A4G16_05475	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A4G16_05480	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
A4G16_05490	ENOG4108RRZ	Transcription elongation factor GreB
A4G16_05505	ENOG4107QKA	exodeoxyribonuclease V beta
A4G16_05510	ENOG4107QI1	Mate efflux family protein
A4G16_05515	ENOG4107RUE	extracellular solute-binding protein family 1
A4G16_05520	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4G16_05525	ENOG4108VMM	UPF0756 membrane protein
A4G16_05530	ENOG4105CQ7	ATP-dependent helicase
A4G16_05540	ENOG4108MJ5	VirK protein
A4G16_05545	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A4G16_05550	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A4G16_05560	ENOG4107TT5	NLP P60 protein
A4G16_05570	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
A4G16_05580	ENOG4108Q67	UPF0319 protein
A4G16_05585	ENOG4108JU5	Magnesium and cobalt efflux protein
A4G16_05590	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A4G16_05600	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4G16_05605	ENOG4108R6K	riboflavin synthase, subunit alpha
A4G16_05610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A4G16_05615	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A4G16_05620	ENOG4105EMY	transcriptional regulator
A4G16_05635	ENOG4105W1T	Glycosyl Transferase
A4G16_05645	ENOG4105CPK	Glycosyl transferase (Group 1
A4G16_05655	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A4G16_05660	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A4G16_05665	ENOG4105C9A	Phoh family
A4G16_05680	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A4G16_05685	ENOG4105C28	cystathionine
A4G16_05695	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A4G16_05700	ENOG4105D6S	protein involved in catabolism of external DNA
A4G16_05705	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A4G16_05710	ENOG4105D3G	Pseudouridine synthase
A4G16_05730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4G16_05735	ENOG4105C2C	drug resistance transporter, Bcr CflA
A4G16_05740	ENOG4105I08	Pseudouridine synthase
A4G16_05745	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
A4G16_05750	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A4G16_05760	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A4G16_05765	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
A4G16_05780	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A4G16_05785	ENOG4106K28	UPF0283 membrane protein
A4G16_05790	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A4G16_05800	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A4G16_05805	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A4G16_05810	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A4G16_05825	ENOG4105E02	MotA TolQ exbB proton channel
A4G16_05830	ENOG4107YD3	Thioesterase
A4G16_05840	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4G16_05845	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4G16_05870	ENOG4105M6F	mutator MutT protein
A4G16_05900	ENOG4105M85	Bola protein
A4G16_05910	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A4G16_05915	ENOG4108UJU	UPF0301 protein
A4G16_05920	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A4G16_05925	ENOG4105DSF	transport protein
A4G16_05930	ENOG4105BZG	amino acid carrier protein
A4G16_05935	ENOG4105KK6	nuclease
A4G16_05940	ENOG4108JJA	ABC, transporter
A4G16_05945	ENOG4108MBX	Secretion Protein
A4G16_05970	ENOG4105C9B	Cysteine desulfurase
A4G16_05975	ENOG4105CTQ	phosphohexokinase
A4G16_05980	ENOG4108VTV	Inherit from NOG: Membrane
A4G16_05990	ENOG4105C34	Pseudouridine synthase
A4G16_05995	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4G16_06000	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4G16_06005	ENOG4105XQ6	frataxin-like protein
A4G16_06010	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4G16_06020	ENOG41082NX	50s ribosomal protein l35
A4G16_06025	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A4G16_06035	ENOG4108W1A	pseudouridine synthase
A4G16_06045	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A4G16_06065	ENOG4105EE5	Membrane protein terC
A4G16_06080	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A4G16_06085	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
A4G16_06090	ENOG4105D1F	ATP-binding protein
A4G16_06095	ENOG4107TSG	Extracellular solute-binding protein, family 5
A4G16_06100	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A4G16_06105	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A4G16_06110	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A4G16_06115	ENOG4105CKW	Inner membrane protein yedI
A4G16_06125	ENOG410601J	HemY protein
A4G16_06130	ENOG4105ECF	c-methyltransferase
A4G16_06140	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A4G16_06145	ENOG4105C0A	alcohol dehydrogenase
A4G16_06160	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4G16_06165	ENOG4105K8N	protein family UPF0079, ATPase
A4G16_06180	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A4G16_06185	ENOG4105CFP	Peptidase U32
A4G16_06195	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4G16_06200	ENOG4108K5H	permease YjgP YjgQ family protein
A4G16_06205	ENOG4108M8S	permease YjgP YjgQ family protein
A4G16_06215	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4G16_06220	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
A4G16_06225	ENOG4105EWT	decarboxylase family
A4G16_06230	ENOG4105CUZ	uba thif-type nad fad binding protein
A4G16_06235	ENOG4105C5H	ABC transporter
A4G16_06250	ENOG41082EK	Restriction modification system DNA (Specificity
A4G16_06265	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4G16_06295	ENOG4105D0C	transport protein
A4G16_06300	ENOG4105D3Y	Na H antiporter
A4G16_06305	ENOG4105CGK	Exodeoxyribonuclease III
A4G16_06310	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
A4G16_06315	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A4G16_06320	ENOG4108IUZ	ABC transporter
A4G16_06325	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A4G16_06330	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A4G16_06335	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A4G16_06350	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A4G16_06355	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A4G16_06365	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
A4G16_06370	ENOG4108MG3	formate dehydrogenase
A4G16_06375	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A4G16_06380	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4G16_06390	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A4G16_06400	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A4G16_06405	ENOG4105C8N	cysteinyl-tRNA synthetase
A4G16_06410	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A4G16_06415	ENOG4108UMI	ABC transporter, permease
A4G16_06420	ENOG4105D01	(LipO)protein
A4G16_06425	ENOG4105D01	(LipO)protein
A4G16_06430	ENOG4105D01	(LipO)protein
A4G16_06435	ENOG4105C25	Primosomal protein n'
A4G16_06440	ENOG410829K	Lysine exporter protein (Lyse ygga)
A4G16_06445	ENOG4105DTR	rard protein
A4G16_06450	ENOG4105CHM	Aminotransferase
A4G16_06455	ENOG4105E4F	Isochorismate synthase
A4G16_06465	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A4G16_06470	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A4G16_06475	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A4G16_06480	ENOG4105W0Z	cytoplasmic protein
A4G16_06485	ENOG4107QP8	phosphohexose isomerase
A4G16_06495	ENOG4105DC8	reductase
A4G16_06500	ENOG4108TEB	UPF0114 protein
A4G16_06505	ENOG4108TVJ	Nitroreductase
A4G16_06515	ENOG4105D2N	Aldolase
A4G16_06520	ENOG4105BZA	Phosphoglycerate kinase
A4G16_06525	ENOG4105C8J	)-transporter
A4G16_06530	ENOG4105DFE	Dna adenine methylase
A4G16_06535	ENOG4105D49	3-dehydroquinate synthase
A4G16_06540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4G16_06545	ENOG4108JQC	penicillin-binding protein 1A
A4G16_06570	ENOG4105E4G	Type IV pilus
A4G16_06575	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A4G16_06580	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A4G16_06585	ENOG4108ZAI	phosphatidylglycerophosphatase a
A4G16_06590	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
A4G16_06595	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A4G16_06610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4G16_06615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G16_06620	ENOG4108JQ5	ABC transporter
A4G16_06625	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A4G16_06645	ENOG4105EYM	Major Facilitator superfamily
A4G16_06650	ENOG4105E0A	ABC, transporter
A4G16_06660	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A4G16_06675	ENOG4105RHG	
A4G16_06680	ENOG4105Z2P	Protein of unknown function (DUF465)
A4G16_06690	ENOG4105C4R	Atp-dependent dna helicase
A4G16_06695	ENOG4105ECP	epimerase
A4G16_06715	ENOG4108VPT	UPF0234 protein
A4G16_06720	ENOG4105EAC	phosphoserine phosphatase
A4G16_06725	ENOG41062Z9	Membrane
A4G16_06730	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A4G16_06745	ENOG4105CBX	hi0933 family
A4G16_06750	ENOG41090EX	DsrE family
A4G16_06755	ENOG4105C7N	Xanthine uracil vitamin C permease
A4G16_06765	ENOG4105NNH	LexA regulated protein
A4G16_06770	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A4G16_06775	ENOG41090R7	Ferric uptake
A4G16_06780	ENOG4105DY2	Paraquat-inducible protein b
A4G16_06785	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A4G16_06790	ENOG4105BZ1	(ABC) transporter
A4G16_06810	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A4G16_06815	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A4G16_06820	ENOG4105N21	Membrane
A4G16_06830	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A4G16_06835	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
A4G16_06840	ENOG4105CH7	arginosuccinase
A4G16_06855	ENOG4105CJ2	(LipO)protein
A4G16_06860	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
A4G16_06865	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G16_06870	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G16_06875	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G16_06880	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G16_06885	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A4G16_06890	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A4G16_06895	ENOG4105C2W	permease
A4G16_06905	ENOG4105DIJ	Phosphoethanolamine transferase
A4G16_06915	ENOG4107R11	Transcriptional regulator
A4G16_06920	ENOG4105PAD	Hydrolase
A4G16_06925	ENOG4105ETT	transcriptional Regulator, LysR family
A4G16_06930	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A4G16_06940	ENOG4105K59	histidine triad (HIT) protein
A4G16_06950	ENOG4105C5X	domain protein
A4G16_06955	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A4G16_06960	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A4G16_06965	ENOG4105CN1	protease
A4G16_06970	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A4G16_06980	ENOG4105D8G	Major Facilitator superfamily
A4G16_06985	ENOG4105II7	pyrroline-5-carboxylate reductase
A4G16_06995	ENOG4107VXZ	Hydrolase
A4G16_07005	ENOG4105CWC	Acetylornithine deacetylase
A4G16_07010	ENOG4105W4M	Transport-associated protein
A4G16_07015	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4G16_07020	ENOG41082RQ	UPF0102 protein
A4G16_07025	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A4G16_07030	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A4G16_07035	ENOG4105CA0	peroxidase
A4G16_07045	ENOG4105CK7	Sodium proline symporter
A4G16_07050	ENOG4105J4Q	Transcriptional regulator
A4G16_07055	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A4G16_07070	ENOG4105E07	UPF0149 protein
A4G16_07080	ENOG4105R2J	Conserved Protein
A4G16_07085	ENOG4105K70	DNA-binding protein
A4G16_07090	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A4G16_07150	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A4G16_07155	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G16_07160	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A4G16_07165	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A4G16_07175	ENOG4105CPF	Cell wall formation (By similarity)
A4G16_07185	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A4G16_07190	ENOG4105CNI	cell division protein FtsW
A4G16_07195	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A4G16_07200	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A4G16_07205	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A4G16_07210	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A4G16_07215	ENOG4105CJN	penicillin-binding protein
A4G16_07225	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4G16_07240	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A4G16_07245	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A4G16_07255	ENOG4105NXV	High-affinity zinc uptake system protein
A4G16_07260	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A4G16_07265	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
A4G16_07270	ENOG4105C03	ribonuclease
A4G16_07285	ENOG4108WZM	domain protein
A4G16_07295	ENOG4107YB6	acetyltransferase, (GNAT) family
A4G16_07305	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A4G16_07310	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A4G16_07325	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A4G16_07335	ENOG4107RK2	ADP-ribose diphosphatase NudE
A4G16_07340	ENOG4105VEJ	Heat shock protein
A4G16_07350	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A4G16_07355	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A4G16_07360	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A4G16_07365	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A4G16_07375	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A4G16_07400	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A4G16_07410	ENOG4108WPU	DNA polymerase III subunit psi
A4G16_07415	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A4G16_07420	ENOG4105CI3	gtp-binding protein typa
A4G16_07425	ENOG4105DFA	alanine racemase domain protein
A4G16_07430	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A4G16_07440	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4G16_07445	ENOG4105CXY	transporter
A4G16_07455	ENOG4105CUC	YeeE YedE family protein
A4G16_07465	ENOG4105D7W	serine acetyltransferase
A4G16_07470	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4G16_07475	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A4G16_07480	ENOG4107YZP	Rhodanese domain protein
A4G16_07485	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4G16_07495	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A4G16_07500	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A4G16_07505	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A4G16_07510	ENOG4105D16	lipopolysaccharide heptosyltransferase i
A4G16_07515	ENOG4105XA0	heptosyltransferase ii
A4G16_07525	ENOG4108UBT	opacity-associated protein
A4G16_07530	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A4G16_07535	ENOG4105DJ4	phosphatidylserine decarboxylase
A4G16_07540	ENOG4105D9M	gamma-glutamylcysteine synthetase
A4G16_07545	ENOG4105DAS	pts system
A4G16_07550	ENOG4105ETZ	PTS System
A4G16_07555	ENOG4105F3R	pts system mannose fructose sorbose family iid
A4G16_07565	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A4G16_07570	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A4G16_07575	ENOG4108UM1	dedA family
A4G16_07590	ENOG4108K5P	(LipO)protein
A4G16_07600	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A4G16_07605	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4G16_07610	ENOG4105DJV	ribulose-phosphate 3-epimerase
A4G16_07615	ENOG4105NRA	50s ribosomal protein l31 type b
A4G16_07620	ENOG4105YK5	50S ribosomal protein L36
A4G16_07625	ENOG4108VIA	integral membrane protein
A4G16_07630	ENOG41090ED	Protein with unknown function (DUF469)
A4G16_07635	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A4G16_07640	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4G16_07645	ENOG4105DSB	aldose 1-epimerase
A4G16_07650	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A4G16_07655	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A4G16_07665	ENOG4108Z33	Thiol disulfide Interchange Protein
A4G16_07670	ENOG4105KZW	UPF0381 protein
A4G16_07675	ENOG4105C1J	atp-dependent rna helicase
A4G16_07680	ENOG41090BQ	Glutaredoxin
A4G16_07685	ENOG4105C8J	)-transporter
A4G16_07690	ENOG4108JU6	CBS domain protein
A4G16_07695	ENOG4106KVJ	cytochrome C assembly protein
A4G16_07700	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A4G16_07705	ENOG4105VGS	50s ribosomal protein l32
A4G16_07710	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A4G16_07715	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A4G16_07730	ENOG41060A7	DNA polymerase beta domain protein region
A4G16_07735	ENOG41062MS	nucleotidyltransferase substrate binding protein
A4G16_07740	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A4G16_07745	ENOG4105H2K	paraquat-inducible protein a
A4G16_07750	ENOG4105EM2	membrane
A4G16_07755	ENOG4108Z5K	methylglyoxal synthase
A4G16_07760	ENOG4105D98	threonine synthase
A4G16_07765	ENOG4105EHV	domain protein
A4G16_07775	ENOG4105EJ2	Transcriptional regulator
A4G16_07795	ENOG4105DFU	Cell wall formation (By similarity)
A4G16_07800	ENOG410903C	(LipO)protein
A4G16_07805	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A4G16_07810	ENOG4105RG0	Membrane
A4G16_07815	ENOG4108IA2	Sodium pantothenate symporter
A4G16_07820	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A4G16_07835	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
A4G16_07840	ENOG41087AY	ADP-Ribose pyrophosphatase
A4G16_07860	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
A4G16_07865	ENOG4107YCY	Transcriptional regulator
A4G16_07870	ENOG4105DMW	Dehydrogenase reductase
A4G16_07880	ENOG4105D17	glycoside hydrolase, family 3 domain protein
A4G16_07895	ENOG4108UHU	Aldolase
A4G16_07900	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A4G16_07910	ENOG4108J2R	molybdopterin oxidoreductase
A4G16_07915	ENOG4105CUW	cytochrome C-TYPE protein
A4G16_07925	ENOG4105CUW	cytochrome C-TYPE protein
A4G16_07930	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
A4G16_07935	ENOG4105GXZ	Ferredoxin-type protein NapH
A4G16_07940	ENOG4108BGM	Quinol dehydrogenase periplasmic component
A4G16_07945	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4G16_07960	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
A4G16_07965	ENOG4105DY8	decarboxylase
A4G16_07970	ENOG4108JPW	Aminotransferase
A4G16_07980	ENOG4105KDC	50s ribosomal protein l28
A4G16_07985	ENOG4105W5Q	DNA repair protein (RadC
A4G16_07990	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A4G16_08000	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A4G16_08005	ENOG4105YP7	UPF0270 protein
A4G16_08010	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
A4G16_08015	ENOG4105D4A	Cell wall formation (By similarity)
A4G16_08020	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A4G16_08025	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G16_08030	ENOG4105CNT	hydrolase family 2
A4G16_08040	ENOG4105CSH	Transporter
A4G16_08055	ENOG4105CW7	secretion protein, HlyD family
A4G16_08080	ENOG4105HF0	Membrane
A4G16_08090	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4G16_08095	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4G16_08105	ENOG4105CBG	Sulfatase
A4G16_08125	ENOG4105C4X	radical SAM domain protein
A4G16_08135	ENOG4105D0M	Protease HtpX homolog
A4G16_08140	ENOG4105F0N	pyrophosphate phospho-hydrolase
A4G16_08160	ENOG4105HHA	aminodeoxychorismate lyase
A4G16_08165	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A4G16_08170	ENOG4107QRG	dna polymerase iii
A4G16_08175	ENOG4105F8V	Hydrolase, tatD family
A4G16_08180	ENOG4105RX8	Protein of unknown function (DUF1523)
A4G16_08185	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
A4G16_08190	ENOG4105K64	Glycosyl transferase, family 2
A4G16_08225	ENOG4106AFN	Lyase and sodium transporter (By similarity)
A4G16_08230	ENOG4107QSA	Oxaloacetate decarboxylase
A4G16_08235	ENOG4105D9Q	decarboxylase (Beta subunit)
A4G16_08240	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4G16_08250	ENOG4108XTF	Outer Membrane Lipoprotein
A4G16_08255	ENOG4105NBI	YecM protein
A4G16_08260	ENOG4105C75	arginyL-tRNA synthetase
A4G16_08265	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A4G16_08280	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
A4G16_08285	ENOG4105DA4	cytochrome c-type biogenesis protein
A4G16_08295	ENOG4105X3C	heme exporter protein
A4G16_08300	ENOG41060IM	Heme exporter protein
A4G16_08305	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A4G16_08310	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
A4G16_08315	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
A4G16_08320	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4G16_08325	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4G16_08330	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4G16_08335	ENOG4105C3U	ABC transporter
A4G16_08340	ENOG4108JQ7	(ABC) transporter
A4G16_08345	ENOG4105ERU	peptidase
A4G16_08350	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4G16_08355	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4G16_08360	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A4G16_08370	ENOG4105WBN	Transcriptional regulator (LacI family
A4G16_08380	ENOG4105D7K	pfkb domain protein
A4G16_08385	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4G16_08390	ENOG4105C5Y	PTS System
A4G16_08395	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4G16_08400	ENOG4105KZ7	phosphocarrier protein hpr
A4G16_08405	ENOG4106SMU	thiamine transporter membrane protein
A4G16_08410	ENOG4107T0D	ABC, transporter
A4G16_08415	ENOG4105C5Y	PTS System
A4G16_08420	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A4G16_08425	ENOG4105EX9	Membrane
A4G16_08430	ENOG4105C2I	pirin domain protein
A4G16_08435	ENOG4105D52	delta-aminolevulinic acid dehydratase
A4G16_08440	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A4G16_08445	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A4G16_08450	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A4G16_08455	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A4G16_08465	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4G16_08470	ENOG4107QUT	magnesium and cobalt transport protein CorA
A4G16_08475	ENOG4108QD1	Membrane
A4G16_08480	ENOG4105DBV	ornithine carbamoyltransferase
A4G16_08485	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A4G16_08490	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A4G16_08495	ENOG4105MGM	doxx family
A4G16_08500	ENOG4105MJ2	Competence protein
A4G16_08505	ENOG4108X4Q	Hydrolase
A4G16_08510	ENOG4105QYV	Membrane
A4G16_08520	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A4G16_08525	ENOG4105EAH	synthase
A4G16_08530	ENOG4105WPN	DNA integration recombination invertion protein
A4G16_08535	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A4G16_08540	ENOG4105CHR	reductase
A4G16_08545	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A4G16_08555	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A4G16_08560	ENOG4107S2Z	UPF0761 membrane protein
A4G16_08585	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A4G16_08590	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A4G16_08610	ENOG4108YZA	Nitrogen regulatory protein pii
A4G16_08620	ENOG4105CFG	Acts as a chaperone (By similarity)
A4G16_08640	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A4G16_08645	ENOG4108RMU	ferritin dps family protein
A4G16_08650	ENOG4105BZ4	penicillin-binding protein
A4G16_08655	ENOG4108IPT	Naphthoate synthase
A4G16_08670	ENOG4105CUC	YeeE YedE family protein
A4G16_08675	ENOG4105EEQ	Na H antiporter
A4G16_08680	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A4G16_08685	ENOG4105KUZ	arsenate reductase
A4G16_08690	ENOG4105EEI	dihydropteroate synthase
A4G16_08695	ENOG4105EI2	Pseudouridine synthase
A4G16_08710	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A4G16_08715	ENOG4107QXK	peptidase
A4G16_08720	ENOG4105DSY	exodeoxyribonuclease V, gamma
A4G16_08745	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A4G16_08755	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
A4G16_08765	ENOG4105CQB	FAD linked oxidase domain protein
A4G16_08770	ENOG4105KA0	thioesterase Superfamily protein
A4G16_08780	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A4G16_08785	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A4G16_08795	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A4G16_08840	ENOG4107QX9	Thiol disulfide interChange protein
A4G16_08845	ENOG4108M1T	Cytochrome c-type biogenesis protein
A4G16_08850	ENOG4108M1T	Cytochrome c-type biogenesis protein
A4G16_08855	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A4G16_08860	ENOG4108YZA	Nitrogen regulatory protein pii
A4G16_08865	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A4G16_08870	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A4G16_08875	ENOG410863D	Flavinator of succinate dehydrogenase
A4G16_08880	ENOG4108WFC	UPF0438 protein yifE
A4G16_08900	ENOG4105WD1	Membrane
A4G16_08920	ENOG4105WWK	YheO domain protein
A4G16_08925	ENOG4105C44	Serine transporter
A4G16_08950	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
A4G16_08955	ENOG4108RXX	maleylacetoacetate isomerase
A4G16_08960	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A4G16_08965	ENOG4108HWV	)-transporter
A4G16_08970	ENOG4105C2J	ABC transporter
A4G16_08975	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
A4G16_08980	ENOG4105KZW	UPF0381 protein
A4G16_08985	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A4G16_08990	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
A4G16_08995	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A4G16_09010	ENOG4105C0P	Mg chelatase subunit ChlI
A4G16_09020	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A4G16_09030	ENOG41063M6	Cell Division Protein
A4G16_09035	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A4G16_09045	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A4G16_09050	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A4G16_09055	ENOG4108ST3	glycosyltransferase
A4G16_09060	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A4G16_09065	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A4G16_09070	ENOG4105EZE	Cupin 4 family protein
A4G16_09075	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
A4G16_09080	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A4G16_09085	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A4G16_09090	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A4G16_09095	ENOG4105K5M	30s ribosomal protein S16
A4G16_09105	ENOG4108ZT0	50S ribosomal protein l17
A4G16_09110	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4G16_09115	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A4G16_09120	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A4G16_09135	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A4G16_09140	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A4G16_09145	ENOG4105VPB	50S ribosomal protein L30
A4G16_09150	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A4G16_09155	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A4G16_09160	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A4G16_09165	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A4G16_09175	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A4G16_09190	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A4G16_09195	ENOG41083MP	50s ribosomal protein l29
A4G16_09200	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A4G16_09205	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A4G16_09210	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A4G16_09215	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A4G16_09220	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A4G16_09225	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A4G16_09230	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A4G16_09235	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A4G16_09250	ENOG4105C9Q	fumarate hydratase class II
A4G16_09255	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A4G16_09260	ENOG4108K3A	Glutathione S-transferase
A4G16_09265	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A4G16_09270	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A4G16_09295	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A4G16_09300	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A4G16_09305	ENOG4105E33	succinate dehydrogenase
A4G16_09310	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A4G16_09315	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A4G16_09320	ENOG4105FR1	rard protein
A4G16_09335	ENOG4105CJR	Integral membrane protein (MviN
A4G16_09345	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A4G16_09350	ENOG4108RR8	protoporphyrinogen oxidase
A4G16_09355	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A4G16_09360	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A4G16_09370	ENOG4105DKW	ABC transporter
A4G16_09380	ENOG4105CGP	Urocanate hydratase
A4G16_09385	ENOG4105CSH	Transporter
A4G16_09390	ENOG4105C84	Histidine ammonia-lyase
A4G16_09395	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4G16_09400	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4G16_09410	ENOG4105DZ1	carboxypeptidase
A4G16_09420	ENOG4105CNI	cell division protein FtsW
A4G16_09425	ENOG4105CJN	penicillin-binding protein
A4G16_09440	ENOG4105CTS	PTS system mannitol-specific
A4G16_09455	ENOG4107QWE	)-transporter
A4G16_09470	ENOG4108R0G	Tetratricopeptide repeat protein
A4G16_09490	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A4G16_09495	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4G16_09510	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4G16_09515	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4G16_09560	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A4G16_09570	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A4G16_09575	ENOG4108I5U	Uridine phosphorylase
A4G16_09585	ENOG4108VVK	transcriptional Regulator, AsnC
A4G16_09590	ENOG4105CU9	asparagine synthetase A
A4G16_09605	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A4G16_09610	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A4G16_09615	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A4G16_09620	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G16_09625	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G16_09630	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4G16_09650	ENOG4105CEY	Amp-dependent synthetase and ligase
A4G16_09655	ENOG4105R3P	Inner membrane protein yagU
A4G16_09660	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A4G16_09670	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A4G16_09675	ENOG4105K5B	UPF0225 protein
A4G16_09685	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
A4G16_09690	ENOG4105DD7	kinase (PfkB family
A4G16_09695	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
A4G16_09700	ENOG4105D9N	nucleoside
A4G16_09710	ENOG4105CB5	ATP-dependent DNA helicase recG
A4G16_09715	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A4G16_09725	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A4G16_09735	ENOG4105QTB	Flavodoxin
A4G16_09740	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4G16_09745	ENOG4105EVU	fructokinase
A4G16_09750	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
A4G16_09755	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
A4G16_09770	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A4G16_09775	ENOG4105H1G	trap transporter solute receptor taxi family
A4G16_09790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A4G16_09795	ENOG4105C1A	potassium transporter peripheral membrane
A4G16_09800	ENOG4105DG4	malate L-lactate dehydrogenase
A4G16_09805	ENOG4108R66	Conserved Protein
A4G16_09810	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
A4G16_09815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A4G16_09820	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A4G16_09825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A4G16_09830	ENOG4105C2J	ABC transporter
A4G16_09835	ENOG4107SDZ	Galactoside transport system permease protein mglC
A4G16_09850	ENOG4105CMG	Carbohydrate kinase
A4G16_09855	ENOG4105NE1	Conserved Protein
A4G16_09860	ENOG41076KX	Protein of unknown function (DUF1469)
A4G16_09875	ENOG4105CXY	transporter
A4G16_09880	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A4G16_09885	ENOG4105CXY	transporter
A4G16_09890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4G16_09895	ENOG4107RCV	ABC transporter, permease
A4G16_09900	ENOG4105C4Y	ABC transporter
A4G16_09905	ENOG4105C4Y	ABC transporter
A4G16_09910	ENOG4108MJ5	VirK protein
A4G16_09915	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A4G16_09920	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A4G16_09935	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A4G16_09940	ENOG4105CEN	a g-specific adenine glycosylase
A4G16_09945	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A4G16_09950	ENOG4105E4C	Lytic transglycosylase catalytic
A4G16_09975	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A4G16_09990	ENOG4105BZW	Glycerate kinase
A4G16_09995	ENOG4105C6Z	Gluconate
A4G16_10000	ENOG4107VHA	regulatoR
A4G16_10005	ENOG41063FY	Igab-domain of IgA protease
A4G16_10015	ENOG4105G0K	glycine radical enzyme YjjI family
A4G16_10020	ENOG41076CZ	activating enzyme
A4G16_10025	ENOG4106YJS	accessory processing protein
A4G16_10040	ENOG4105VRX	Protein slyX homolog
A4G16_10045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A4G16_10050	ENOG4105WWK	YheO domain protein
A4G16_10055	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A4G16_10060	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A4G16_10085	ENOG4105F0S	class B acid phosphatase
A4G16_10105	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
A4G16_10110	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A4G16_10115	ENOG4105E5Q	amino acid AbC transporter
A4G16_10125	ENOG4105MVE	transcriptional regulator
A4G16_10130	ENOG4105ZXK	Dehydrogenase
A4G16_10135	ENOG4105G63	Type III effector Hrp-dependent
A4G16_10140	ENOG4105FB2	class II Aldolase
A4G16_10145	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A4G16_10150	ENOG4105EXW	epimerase dehydratase
A4G16_10155	ENOG4105C6Z	Gluconate
A4G16_10170	ENOG4105CDA	abc transporter atp-binding protein
A4G16_10175	ENOG4106PMH	Extracellular solute-binding protein family 3
A4G16_10180	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A4G16_10190	ENOG4105MJ9	esterase
A4G16_10220	ENOG4105CMG	Carbohydrate kinase
A4G16_10230	ENOG4105DFW	ABC transporter
A4G16_10235	ENOG4105C2J	ABC transporter
A4G16_10240	ENOG4108HWW	ABC transporter
A4G16_10245	ENOG4105T16	Transcriptional regulator (AraC family)
A4G16_10250	ENOG4105DIQ	Transcriptional regulator
A4G16_10270	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A4G16_10275	ENOG4105C6Z	Gluconate
A4G16_10280	ENOG4107YNJ	LysR family Transcriptional regulator
A4G16_10290	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A4G16_10295	ENOG4105C26	Dehydrogenase
A4G16_10300	ENOG4105DH8	myo-inositol catabolism
A4G16_10305	ENOG4105C26	Dehydrogenase
A4G16_10310	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A4G16_10315	ENOG4105C2J	ABC transporter
A4G16_10320	ENOG4105CNN	ABC, transporter
A4G16_10330	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
A4G16_10335	ENOG4105CHY	citrate lyase, alpha
A4G16_10340	ENOG4105CI0	Citrate lyase
A4G16_10345	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
A4G16_10350	ENOG4105C7F	AcnD-accessory protein PrpF
A4G16_10355	ENOG4107QPK	)-transporter
A4G16_10360	ENOG4105FDP	GntR family transcriptional regulator
A4G16_10365	ENOG4107QIJ	Aconitate hydratase 2
A4G16_10370	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
A4G16_10375	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A4G16_10380	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
A4G16_10385	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A4G16_10400	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
A4G16_10410	ENOG4105D9R	oxidoreductase
A4G16_10425	ENOG4108WQI	RNA Polymerase
A4G16_10430	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A4G16_10435	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A4G16_10440	ENOG4105HDK	L-asparaginase
A4G16_10455	ENOG4108ETH	Formylglycinamide ribotide synthetase
A4G16_10465	ENOG4107EDW	L-fucose operon activator
A4G16_10470	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
A4G16_10475	ENOG4105CMG	Carbohydrate kinase
A4G16_10480	ENOG4105NWF	RbsD or FucU transport
A4G16_10485	ENOG4107W7X	Aldolase
A4G16_10490	ENOG4105EDR	glucose galactose transporter
A4G16_10495	ENOG4105C0A	alcohol dehydrogenase
A4G16_10505	ENOG410804X	Transcriptional regulator
A4G16_10510	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4G16_10520	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A4G16_10525	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A4G16_10545	ENOG4105I5W	Transporter
A4G16_10555	ENOG4106PMH	Extracellular solute-binding protein family 3
A4G16_10560	ENOG4108KS2	transglutaminase domain protein
A4G16_10570	ENOG410681U	heavy metal transport detoxification protein
A4G16_10575	ENOG4105C2X	Arabinose 5-phosphate isomerase
A4G16_10585	ENOG4105C79	DNA protecting protein DprA
A4G16_10590	ENOG4105PM1	preprotein translocase subunit SecE
A4G16_10595	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A4G16_10600	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A4G16_10605	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A4G16_10610	ENOG4108VZM	50s ribosomal protein L10
A4G16_10615	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4G16_10620	ENOG4107R3N	Filamentation induced by cAMP protein fic
A4G16_10635	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4G16_10660	ENOG4105ESV	Glycosyl transferase, family 4
A4G16_10670	ENOG4108IJ1	Dehydrogenase
A4G16_10675	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
A4G16_10680	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4G16_10685	ENOG4105C5F	glutamine synthetase
A4G16_10690	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
A4G16_10695	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
A4G16_10700	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family