locus-tag	class	description
BG574_00005	COG0445	tRNA wobble uridine modification
BG574_00015	COG0357	Ribosomal RNA small subunit methyltransferase G
BG574_00030	COG0667	Aldo Keto reductase
BG574_00035	COG2271	Major facilitator Superfamily
BG574_00040	COG0584	glycerophosphoryl diester phosphodiesterase
BG574_00045	COG2271	Major facilitator Superfamily
BG574_00090	COG1129	ABC transporter
BG574_00095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG574_00100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG574_00105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG574_00110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG574_00115	COG2731	YhcH YjgK YiaL family protein
BG574_00120	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BG574_00155	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BG574_00160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG574_00185	COG2502	aspartate--ammonia ligase
BG574_00190	COG1522	sequence-specific DNA binding
BG574_00200	COG0716	FMN binding
BG574_00205	COG0747	negative chemotaxis
BG574_00230	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BG574_00245	COG0259	pyridoxamine-phosphate oxidase activity
BG574_00255	COG3276	selenocysteine insertion sequence binding
BG574_00275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG574_00280	COG0569	domain protein
BG574_00285	COG3477	response to acidic pH
BG574_00290	COG1012	belongs to the aldehyde dehydrogenase family
BG574_00295	COG1454	alcohol dehydrogenase
BG574_00300	COG1263	PTS System
BG574_00300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_00305	COG1879	ABC-type sugar transport system periplasmic component
BG574_00310	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG574_00315	COG1129	ABC transporter
BG574_00320	COG0235	Class ii aldolase
BG574_00325	COG4154	Belongs to the RbsD FucU family
BG574_00330	COG1070	Carbohydrate kinase
BG574_00335	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BG574_00340	COG1349	DNA-binding transcription factor activity
BG574_00375	COG1629	transport
BG574_00375	COG4206	TonB-dependent receptor
BG574_00385	COG0252	asparaginase activity
BG574_00390	COG3676	manually curated
BG574_00405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG574_00420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG574_00425	COG1595	DNA-templated transcription, initiation
BG574_00440	COG0673	inositol 2-dehydrogenase activity
BG574_00445	COG1305	Transglutaminase-like
BG574_00455	COG2608	mercury ion transmembrane transporter activity
BG574_00460	COG3730	PTS system glucitol sorbitol-specific
BG574_00475	COG1028	Short-chain dehydrogenase reductase Sdr
BG574_00480	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_00485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG574_00490	COG1349	DNA-binding transcription factor activity
BG574_00495	COG0517	IMP dehydrogenase activity
BG574_00495	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BG574_00515	COG3722	fumarate hydratase activity
BG574_00520	COG0490	domain, Protein
BG574_00520	COG0471	metal ion transport
BG574_00525	COG4214	carbohydrate transport
BG574_00530	COG1129	ABC transporter
BG574_00535	COG4213	ABC transporter substrate-binding protein
BG574_00540	COG2115	Belongs to the xylose isomerase family
BG574_00545	COG1070	Carbohydrate kinase
BG574_00555	COG3545	Serine hydrolase
BG574_00565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BG574_00570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BG574_00575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG574_00580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BG574_00595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG574_00600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG574_00655	COG0697	spore germination
BG574_00660	COG0346	lactoylglutathione lyase activity
BG574_00665	COG1194	a g-specific adenine glycosylase
BG574_00670	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BG574_00675	COG0741	lytic transglycosylase activity
BG574_00700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG574_00705	COG1349	DNA-binding transcription factor activity
BG574_00710	COG2084	Dehydrogenase
BG574_00715	COG3395	kinase activity
BG574_00720	COG0235	Class ii aldolase
BG574_00725	COG3622	Belongs to the hyi family
BG574_00730	COG2610	gluconate transmembrane transporter activity
BG574_00740	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BG574_00765	COG4545	Glutaredoxin-related protein
BG574_00770	COG4804	nuclease activity
BG574_00795	COG2964	Protein conserved in bacteria
BG574_00810	COG2832	Protein of unknown function (DUF454)
BG574_00830	COG3085	chromosome segregation
BG574_00835	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BG574_00845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BG574_00855	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG574_00875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG574_00920	COG1840	ABC-type Fe3 transport system, periplasmic component
BG574_00930	COG1349	DNA-binding transcription factor activity
BG574_00935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BG574_00940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BG574_00955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG574_00965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BG574_00975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BG574_00985	COG0200	Binds to the 23S rRNA
BG574_00990	COG0201	protein transport
BG574_01000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BG574_01010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BG574_01015	COG0202	RNA polymerase activity
BG574_01020	COG0203	ribosomal protein L17
BG574_01025	COG2207	Transcriptional regulator
BG574_01025	COG1609	Transcriptional regulator
BG574_01030	COG1609	Transcriptional regulator
BG574_01035	COG3265	gluconokinase activity
BG574_01040	COG2610	gluconate transmembrane transporter activity
BG574_01055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BG574_01060	COG1012	belongs to the aldehyde dehydrogenase family
BG574_01065	COG3718	enzyme involved in inositol metabolism
BG574_01075	COG1879	ABC-type sugar transport system periplasmic component
BG574_01080	COG1129	ABC transporter
BG574_01085	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG574_01090	COG0673	inositol 2-dehydrogenase activity
BG574_01105	COG0673	inositol 2-dehydrogenase activity
BG574_01115	COG3962	Belongs to the TPP enzyme family
BG574_01130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG574_01140	COG1263	PTS System
BG574_01140	COG2190	(PTS) system
BG574_01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_01150	COG0228	four-way junction DNA binding
BG574_01155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BG574_01160	COG0336	Belongs to the RNA methyltransferase TrmD family
BG574_01180	COG1694	Mazg nucleotide pyrophosphohydrolase
BG574_01185	COG2850	peptidyl-arginine hydroxylation
BG574_01190	COG0439	Biotin carboxylase
BG574_01195	COG0511	ligase activity, forming carbon-carbon bonds
BG574_01205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BG574_01220	COG1876	peptidase activity
BG574_01230	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BG574_01235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG574_01245	COG0606	chelatase, subunit chli
BG574_01250	COG2267	carboxylic ester hydrolase activity
BG574_01285	COG3691	Protein conserved in bacteria
BG574_01295	COG1879	ABC-type sugar transport system periplasmic component
BG574_01300	COG1879	ABC-type sugar transport system periplasmic component
BG574_01310	COG4211	Belongs to the binding-protein-dependent transport system permease family
BG574_01315	COG0747	negative chemotaxis
BG574_01320	COG0747	negative chemotaxis
BG574_01335	COG4795	General secretion pathway protein
BG574_01350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BG574_01360	COG0747	negative chemotaxis
BG574_01380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BG574_01380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BG574_01385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BG574_01400	COG1309	transcriptional regulator
BG574_01425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG574_01430	COG2003	Belongs to the UPF0758 family
BG574_01445	COG1349	DNA-binding transcription factor activity
BG574_01450	COG3395	kinase activity
BG574_01465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BG574_01470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG574_01475	COG0076	glutamate decarboxylase activity
BG574_01480	COG3111	PFAM Bacterial OB fold (BOF) protein
BG574_01485	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG574_01490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BG574_01495	COG3062	negative regulation of establishment of protein localization
BG574_01500	COG0243	molybdopterin cofactor binding
BG574_01505	COG0437	4 iron, 4 sulfur cluster binding
BG574_01510	COG0348	domain, Protein
BG574_01515	COG3043	anaerobic respiration
BG574_01520	COG3005	denitrification pathway
BG574_01525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BG574_01535	COG3005	denitrification pathway
BG574_01545	COG3381	protein complex oligomerization
BG574_01565	COG0494	nUDIX hydrolase
BG574_01585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BG574_01590	COG4145	pantothenate transmembrane transporter activity
BG574_01595	COG3924	membrane
BG574_01600	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BG574_01605	COG2853	Lipoprotein
BG574_01610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BG574_01620	COG1858	cytochrome C peroxidase
BG574_01645	COG2801	Transposase and inactivated derivatives
BG574_01655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG574_01665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BG574_01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG574_01675	COG0765	amino acid transport
BG574_01680	COG1126	abc transporter atp-binding protein
BG574_01685	COG0762	integral membrane protein
BG574_01690	COG3171	Protein conserved in bacteria
BG574_01695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BG574_01700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG574_01710	COG0805	protein transport
BG574_01715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG574_01720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG574_01725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BG574_01730	COG4804	nuclease activity
BG574_01735	COG3165	ubiquinone biosynthetic process from chorismate
BG574_01740	COG2226	methyltransferase
BG574_01745	COG0598	Magnesium transport protein CorA
BG574_01750	COG3676	manually curated
BG574_01760	COG2801	Transposase and inactivated derivatives
BG574_01765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG574_01795	COG3561	AntA/AntB antirepressor
BG574_01835	COG3723	Recombinational DNA repair protein, rece pathway
BG574_01960	COG3179	chitinase
BG574_01975	COG3728	DNA packaging
BG574_01980	COG1783	phage Terminase large subunit
BG574_02040	COG1598	PFAM Uncharacterised protein family UPF0150
BG574_02045	COG1724	mRNA binding
BG574_02130	COG3321	synthase
BG574_02130	COG0604	alcohol dehydrogenase
BG574_02130	COG1028	Short-chain dehydrogenase reductase Sdr
BG574_02140	COG0778	Nitroreductase
BG574_02145	COG1902	pentaerythritol trinitrate reductase activity
BG574_02155	COG0431	NADPH-dependent FMN reductase
BG574_02165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BG574_02170	COG0668	transmembrane transport
BG574_02175	COG0564	pseudouridine synthase activity
BG574_02180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BG574_02185	COG1393	Belongs to the ArsC family
BG574_02190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG574_02200	COG2391	methyltransferase activity
BG574_02205	COG2391	methyltransferase activity
BG574_02210	COG0425	Belongs to the sulfur carrier protein TusA family
BG574_02215	COG0753	catalase activity
BG574_02235	COG0347	Belongs to the P(II) protein family
BG574_02260	COG2801	Transposase and inactivated derivatives
BG574_02265	COG2818	Glycosylase
BG574_02275	COG1388	LysM domain
BG574_02275	COG4942	peptidase
BG574_02290	COG1238	metal cluster binding
BG574_02295	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BG574_02315	COG3716	PTS system mannose fructose sorbose family IID component
BG574_02320	COG3715	PTS system
BG574_02325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_02325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_02340	COG4974	Belongs to the 'phage' integrase family
BG574_02365	COG0688	phosphatidylethanolamine metabolic process
BG574_02370	COG1555	photosystem II stabilization
BG574_02375	COG3061	Opacity-associated protein A
BG574_02375	COG3266	domain, Protein
BG574_02385	COG0859	PFAM glycosyl transferase family 9
BG574_02390	COG0859	PFAM glycosyl transferase family 9
BG574_02395	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BG574_02400	COG0049	tRNA binding
BG574_02405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG574_02415	COG0544	peptidyl-prolyl cis-trans isomerase activity
BG574_02420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG574_02425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BG574_02430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BG574_02435	COG1045	serine acetyltransferase
BG574_02455	COG0582	viral genome integration into host DNA
BG574_02465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG574_02490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BG574_02505	COG0456	acetyltransferase
BG574_02510	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BG574_02535	COG0131	Imidazoleglycerol-phosphate dehydratase
BG574_02535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG574_02545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BG574_02560	COG0107	imidazoleglycerol-phosphate synthase activity
BG574_02580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BG574_02585	COG0494	nUDIX hydrolase
BG574_02590	COG1218	3'(2'),5'-bisphosphate nucleotidase
BG574_02595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG574_02600	COG0363	glucosamine-6-phosphate deaminase activity
BG574_02610	COG1794	racemase activity, acting on amino acids and derivatives
BG574_02615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG574_02625	COG0525	valine-tRNA ligase activity
BG574_02635	COG4185	zeta toxin
BG574_02640	COG3177	Filamentation induced by cAMP protein fic
BG574_02645	COG2153	protein acetylation
BG574_02650	COG2927	DNA polymerase III (CHI subunit)
BG574_02655	COG1652	LysM domain
BG574_02690	COG2801	Transposase and inactivated derivatives
BG574_02700	COG2801	Transposase and inactivated derivatives
BG574_02705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG574_02720	COG3077	Addiction module antitoxin, RelB DinJ family
BG574_02725	COG3041	Addiction module toxin RelE StbE family
BG574_02740	COG1295	ribonuclease BN
BG574_02745	COG1490	D-aminoacyl-tRNA deacylase activity
BG574_02755	COG1114	Component of the transport system for branched-chain amino acids
BG574_02760	COG1028	Short-chain dehydrogenase reductase Sdr
BG574_02770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BG574_02775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BG574_02780	COG0142	geranyltranstransferase activity
BG574_02785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BG574_02790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BG574_02795	COG0697	spore germination
BG574_02800	COG0697	spore germination
BG574_02805	COG0561	phosphatase activity
BG574_02810	COG1040	competence protein
BG574_02815	COG2259	Doxx family
BG574_02820	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BG574_02830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BG574_02835	COG2801	Transposase and inactivated derivatives
BG574_02845	COG0783	Belongs to the Dps family
BG574_02850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG574_02855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BG574_02870	COG3676	manually curated
BG574_02875	COG2801	Transposase and inactivated derivatives
BG574_02910	COG0497	DNA recombination
BG574_02925	COG0849	cell division
BG574_02935	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG574_02945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG574_02950	COG0772	Belongs to the SEDS family
BG574_02955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BG574_02960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG574_02965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG574_02970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG574_02975	COG0768	penicillin binding
BG574_02980	COG3116	cell division
BG574_03000	COG0557	exoribonuclease II activity
BG574_03005	COG2824	Alkylphosphonate utilization operon protein PhnA
BG574_03010	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BG574_03020	COG1917	Cupin 2, conserved barrel domain protein
BG574_03020	COG4977	sequence-specific DNA binding
BG574_03030	COG1530	ribonuclease E activity
BG574_03040	COG2801	Transposase and inactivated derivatives
BG574_03050	COG3068	Protein conserved in bacteria
BG574_03065	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BG574_03075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BG574_03080	COG1414	Transcriptional regulator
BG574_03085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG574_03100	COG3107	peptidoglycan biosynthetic process
BG574_03105	COG0792	nuclease activity
BG574_03110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BG574_03140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG574_03150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG574_03155	COG2814	Major facilitator Superfamily
BG574_03165	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BG574_03170	COG0793	Belongs to the peptidase S41A family
BG574_03175	COG2989	Protein conserved in bacteria
BG574_03180	COG3108	Peptidase M15
BG574_03185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG574_03195	COG0537	adenosine 5'-monophosphoramidase activity
BG574_03205	COG1162	GTPase activity
BG574_03210	COG0583	DNA-binding transcription factor activity
BG574_03215	COG1011	Hydrolase
BG574_03220	COG0583	DNA-binding transcription factor activity
BG574_03230	COG0252	asparaginase activity
BG574_03240	COG0316	Belongs to the HesB IscA family
BG574_03240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BG574_03250	COG1805	sodium ion transport
BG574_03255	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BG574_03260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BG574_03265	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BG574_03270	COG2871	sodium ion transport
BG574_03275	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BG574_03280	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BG574_03285	COG1477	protein flavinylation
BG574_03290	COG2991	Protein conserved in bacteria
BG574_03300	COG2801	Transposase and inactivated derivatives
BG574_03320	COG0165	Argininosuccinate lyase
BG574_03325	COG1426	Protein conserved in bacteria
BG574_03330	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BG574_03340	COG2976	Protein conserved in bacteria
BG574_03345	COG0592	DNA-directed DNA polymerase activity
BG574_03350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BG574_03355	COG1132	(ABC) transporter
BG574_03360	COG1854	S-ribosylhomocysteine lyase activity
BG574_03365	COG3008	intermembrane lipid transfer
BG574_03370	COG0735	belongs to the Fur family
BG574_03375	COG0716	FMN binding
BG574_03385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG574_03390	COG2252	PERMEase
BG574_03395	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BG574_03400	COG2081	HI0933 family
BG574_03405	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG574_03415	COG0560	Phosphoserine phosphatase
BG574_03420	COG1666	GTP binding
BG574_03440	COG1090	epimerase
BG574_03445	COG0210	DNA helicase
BG574_03470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG574_03475	COG0009	L-threonylcarbamoyladenylate synthase
BG574_03480	COG0551	DNA topoisomerase type I activity
BG574_03490	COG2137	regulation of response to DNA damage stimulus
BG574_03500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG574_03510	COG1322	Protein conserved in bacteria
BG574_03510	COG1322	Protein conserved in bacteria
BG574_03515	COG0512	Glutamine amidotransferase of anthranilate synthase
BG574_03540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG574_03545	COG4591	ABC-type transport system involved in lipoprotein release permease component
BG574_03550	COG1136	(ABC) transporter
BG574_03555	COG4591	ABC-type transport system involved in lipoprotein release permease component
BG574_03580	COG0084	hydrolase, TatD family'
BG574_03585	COG1966	Carbon starvation protein
BG574_03590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BG574_03595	COG0483	inositol monophosphate 1-phosphatase activity
BG574_03600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG574_03605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG574_03625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BG574_03645	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BG574_03675	COG0629	single-stranded DNA binding
BG574_03705	COG1598	PFAM Uncharacterised protein family UPF0150
BG574_03710	COG1724	mRNA binding
BG574_03755	COG1403	HNH endonuclease
BG574_03790	COG3179	chitinase
BG574_03830	COG0740	serine-type endopeptidase activity
BG574_03905	COG2801	Transposase and inactivated derivatives
BG574_03925	COG2801	Transposase and inactivated derivatives
BG574_03935	COG1629	transport
BG574_03935	COG4206	TonB-dependent receptor
BG574_03940	COG4206	TonB-dependent receptor
BG574_03940	COG1629	transport
BG574_03945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG574_03950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BG574_03955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG574_03975	COG4172	Belongs to the ABC transporter superfamily
BG574_03980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG574_03985	COG0601	transmembrane transport
BG574_03990	COG1177	transmembrane transport
BG574_03995	COG1176	ABC-type spermidine putrescine transport system, permease component I
BG574_04000	COG3842	ATPase activity
BG574_04005	COG0210	DNA helicase
BG574_04010	COG1027	Aspartate ammonia-lyase
BG574_04015	COG3326	Membrane
BG574_04020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BG574_04030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG574_04035	COG3099	Belongs to the UPF0263 family
BG574_04040	COG0742	ribosomal rna small subunit methyltransferase
BG574_04045	COG0552	protein localization to endoplasmic reticulum
BG574_04050	COG2884	Cell division ATP-binding protein ftsE
BG574_04055	COG2177	Part of the ABC transporter FtsEX involved in
BG574_04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG574_04080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_04085	COG1137	ATPase activity
BG574_04090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BG574_04095	COG3117	lipopolysaccharide transmembrane transporter activity
BG574_04100	COG0708	Exodeoxyribonuclease III
BG574_04105	COG2056	Na+-H+ antiporter family
BG574_04115	COG1640	4-alpha-glucanotransferase
BG574_04120	COG0058	SHG alpha-glucan phosphorylase activity
BG574_04125	COG2909	trisaccharide binding
BG574_04130	COG0366	Alpha amylase catalytic
BG574_04135	COG3833	ABC-type maltose transport systems, permease component
BG574_04140	COG1175	transmembrane transport
BG574_04150	COG3842	ATPase activity
BG574_04155	COG4580	involved in the transport of maltose and maltodextrins
BG574_04165	COG0475	glutathione-regulated potassium exporter activity
BG574_04165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG574_04175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG574_04200	COG3115	cell septum assembly
BG574_04230	COG3118	belongs to the thioredoxin family
BG574_04235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG574_04235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_04235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BG574_04240	COG1461	Dihydroxyacetone kinase
BG574_04245	COG2376	Dihydroxyacetone kinase
BG574_04250	COG0492	ferredoxin-NADP+ reductase activity
BG574_04260	COG3753	Protein conserved in bacteria
BG574_04265	COG0402	S-adenosylhomocysteine deaminase activity
BG574_04270	COG4143	(ABC) transporter
BG574_04275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BG574_04280	COG0617	tRNA 3'-terminal CCA addition
BG574_04285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG574_04295	COG2911	Protein conserved in bacteria
BG574_04310	COG0346	lactoylglutathione lyase activity
BG574_04315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BG574_04325	COG1629	transport
BG574_04325	COG4771	TonB-dependent receptor
BG574_04335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG574_04340	COG2062	phosphohistidine phosphatase, SixA
BG574_04345	COG0469	pyruvate kinase activity
BG574_04350	COG0859	PFAM glycosyl transferase family 9
BG574_04355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BG574_04360	COG1605	Chorismate mutase
BG574_04360	COG0287	Prephenate dehydrogenase
BG574_04370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BG574_04375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BG574_04380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BG574_04385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG574_04395	COG0251	oxidation-reduction process
BG574_04400	COG1022	Amp-dependent synthetase and ligase
BG574_04405	COG3101	peptidyl-lysine hydroxylation
BG574_04410	COG4232	protein-disulfide reductase activity
BG574_04415	COG1126	abc transporter atp-binding protein
BG574_04420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG574_04425	COG4215	(ABC) transporter
BG574_04430	COG4160	amino acid transport
BG574_04435	COG2255	four-way junction helicase activity
BG574_04440	COG0632	four-way junction helicase activity
BG574_04445	COG1280	lysine exporter protein (LysE YggA)
BG574_04450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG574_04455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BG574_04460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG574_04465	COG4796	Type ii and iii secretion system protein
BG574_04490	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BG574_04495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BG574_04500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BG574_04505	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BG574_04510	COG0733	neurotransmitter:sodium symporter activity
BG574_04515	COG0126	phosphoglycerate kinase activity
BG574_04520	COG0191	fructose-bisphosphate aldolase activity
BG574_04525	COG4172	Belongs to the ABC transporter superfamily
BG574_04530	COG0778	Nitroreductase
BG574_04540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG574_04550	COG3058	Necessary for formate dehydrogenase activity
BG574_04555	COG2864	formate dehydrogenase
BG574_04560	COG0437	4 iron, 4 sulfur cluster binding
BG574_04565	COG3383	formate dehydrogenase (NAD+) activity
BG574_04565	COG0243	molybdopterin cofactor binding
BG574_04570	COG0243	molybdopterin cofactor binding
BG574_04570	COG3383	formate dehydrogenase (NAD+) activity
BG574_04585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BG574_04590	COG0215	cysteine-tRNA ligase activity
BG574_04595	COG0083	homoserine kinase activity
BG574_04600	COG0527	aspartate kinase activity
BG574_04600	COG0460	homoserine dehydrogenase
BG574_04615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG574_04620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BG574_04650	COG0166	Belongs to the GPI family
BG574_04655	COG2960	long-chain fatty acid transporting porin activity
BG574_04665	COG0720	synthase
BG574_04670	COG0602	queuosine metabolic process
BG574_04680	COG3676	manually curated
BG574_04690	COG1169	isochorismate synthase
BG574_04695	COG0436	Aminotransferase
BG574_04705	COG1280	lysine exporter protein (LysE YggA)
BG574_04710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG574_04715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BG574_04725	COG2089	acid synthase
BG574_04740	COG2244	polysaccharide biosynthetic process
BG574_04750	COG3306	glycosyltransferase involved in LPS biosynthesis
BG574_04760	COG1216	Glycosyl transferase, family 2
BG574_04765	COG1216	Glycosyl transferase, family 2
BG574_04775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG574_04785	COG0813	purine-nucleoside phosphorylase activity
BG574_04790	COG2207	Transcriptional regulator
BG574_04795	COG1764	response to oxidative stress
BG574_04805	COG1902	pentaerythritol trinitrate reductase activity
BG574_04815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BG574_04825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG574_04830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_04830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_04835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_04840	COG3715	PTS system
BG574_04845	COG3716	PTS system mannose fructose sorbose family IID component
BG574_04860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_04860	COG3711	transcriptional antiterminator
BG574_04875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BG574_04880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG574_04885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BG574_04895	COG0795	lipopolysaccharide-transporting ATPase activity
BG574_04900	COG0795	lipopolysaccharide-transporting ATPase activity
BG574_04920	COG1519	Transferase
BG574_04930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BG574_04935	COG0802	atpase or kinase
BG574_04940	COG1388	LysM domain
BG574_04940	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG574_04945	COG2801	Transposase and inactivated derivatives
BG574_04950	COG0531	amino acid
BG574_04960	COG1454	alcohol dehydrogenase
BG574_04960	COG1012	belongs to the aldehyde dehydrogenase family
BG574_04965	COG0181	hydroxymethylbilane synthase activity
BG574_04975	COG2959	enzyme of heme biosynthesis
BG574_04980	COG3071	HemY protein
BG574_04985	COG2354	Protein conserved in bacteria
BG574_04990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BG574_04995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG574_05000	COG2095	MarC family integral membrane protein
BG574_05005	COG4166	transmembrane transport
BG574_05010	COG0489	protein tyrosine kinase activity
BG574_05015	COG3642	lipopolysaccharide core region biosynthetic process
BG574_05020	COG0302	gtp cyclohydrolase
BG574_05030	COG2217	Heavy metal translocating P-type atpase
BG574_05035	COG2217	Heavy metal translocating P-type atpase
BG574_05040	COG0789	Transcriptional regulator
BG574_05045	COG2801	Transposase and inactivated derivatives
BG574_05065	COG0187	DNA topoisomerase II activity
BG574_05075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BG574_05085	COG0295	cytidine deaminase activity
BG574_05090	COG0471	metal ion transport
BG574_05095	COG0471	metal ion transport
BG574_05100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BG574_05105	COG0542	response to heat
BG574_05110	COG3047	cAMP biosynthetic process
BG574_05125	COG3676	manually curated
BG574_05130	COG0330	HflC and HflK could
BG574_05135	COG0330	HflC and HflK could
BG574_05160	COG0301	tRNA thio-modification
BG574_05160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG574_05170	COG0205	6-phosphofructokinase activity
BG574_05175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG574_05210	COG3676	manually curated
BG574_05240	COG1525	nuclease
BG574_05245	COG1115	amino acid carrier protein
BG574_05250	COG0628	permease
BG574_05260	COG1678	Uncharacterized ACR, COG1678
BG574_05265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG574_05280	COG0271	Belongs to the BolA IbaG family
BG574_05310	COG0494	nUDIX hydrolase
BG574_05315	COG2801	Transposase and inactivated derivatives
BG574_05340	COG1271	oxidase subunit
BG574_05345	COG1294	oxidase, subunit
BG574_05355	COG0824	Thioesterase
BG574_05360	COG0811	peptide transport
BG574_05365	COG0848	biopolymer transport protein
BG574_05370	COG3064	Membrane
BG574_05375	COG0823	Involved in the tonB-independent uptake of proteins
BG574_05390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BG574_05400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG574_05415	COG0564	pseudouridine synthase activity
BG574_05440	COG2095	MarC family integral membrane protein
BG574_05445	COG0303	'Molybdopterin
BG574_05450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG574_05460	COG3092	negative regulation of chromosome organization
BG574_05470	COG2917	probably involved in intracellular septation
BG574_05475	COG1607	acyl-coa hydrolase
BG574_05480	COG2350	Protein conserved in bacteria
BG574_05490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BG574_05500	COG0732	type I restriction modification DNA specificity domain
BG574_05505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BG574_05525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG574_05530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BG574_05535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BG574_05555	COG1953	Uracil, thiamine, allantoin
BG574_05565	COG3257	ureidoglycine aminohydrolase activity
BG574_05570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BG574_05575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BG574_05580	COG0549	Belongs to the carbamate kinase family
BG574_05585	COG1620	l-lactate permease
BG574_05595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG574_05600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BG574_05610	COG1595	DNA-templated transcription, initiation
BG574_05615	COG3219	Protein conserved in bacteria
BG574_05630	COG2259	Doxx family
BG574_05645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BG574_05650	COG0481	GTPase activity
BG574_05655	COG0681	Belongs to the peptidase S26 family
BG574_05665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG574_05675	COG0513	Belongs to the DEAD box helicase family
BG574_05680	COG0433	COG0433 Predicted ATPase
BG574_05685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BG574_05690	COG3842	ATPase activity
BG574_05700	COG1840	ABC-type Fe3 transport system, periplasmic component
BG574_05715	COG2194	sulfuric ester hydrolase activity
BG574_05720	COG0528	UMP kinase activity
BG574_05725	COG0233	cytoplasmic translational termination
BG574_05735	COG4942	peptidase
BG574_05745	COG0729	surface antigen
BG574_05750	COG2911	Protein conserved in bacteria
BG574_05755	COG4988	ABC transporter
BG574_05760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BG574_05765	COG2915	High frequency lysogenization protein hflD homolog
BG574_05770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG574_05775	COG1349	DNA-binding transcription factor activity
BG574_05780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BG574_05800	COG0187	DNA topoisomerase II activity
BG574_05805	COG0500	methyltransferase
BG574_05810	COG1944	ATP diphosphatase activity
BG574_05855	COG1518	maintenance of DNA repeat elements
BG574_05865	COG1530	ribonuclease E activity
BG574_05870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BG574_05875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG574_05880	COG2949	membrane
BG574_05885	COG0788	formyltetrahydrofolate deformylase activity
BG574_05890	COG2916	Histone family protein nucleoid-structuring protein H-NS
BG574_05895	COG1757	Na H antiporter
BG574_05900	COG4221	oxidoreductase activity
BG574_05910	COG0159	tryptophan synthase activity
BG574_05915	COG5339	Protein conserved in bacteria
BG574_05920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG574_05920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG574_05925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BG574_05935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG574_05945	COG0189	ligase activity
BG574_05950	COG0280	phosphate acetyltransferase
BG574_05950	COG0281	malic enzyme
BG574_05965	COG3683	transport system, periplasmic component
BG574_05970	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BG574_05975	COG1115	amino acid carrier protein
BG574_05980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BG574_05985	COG0045	succinate-CoA ligase (ADP-forming) activity
BG574_05990	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG574_05995	COG0567	Dehydrogenase, E1 component
BG574_06000	COG1121	(ABC) transporter
BG574_06005	COG0739	heme binding
BG574_06010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG574_06015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG574_06025	COG0561	phosphatase activity
BG574_06030	COG3850	Histidine kinase
BG574_06040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BG574_06045	COG0393	Putative heavy-metal-binding
BG574_06050	COG2983	Belongs to the UPF0260 family
BG574_06055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BG574_06060	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BG574_06065	COG4166	transmembrane transport
BG574_06070	COG4168	peptide transport system, permease
BG574_06075	COG4171	peptide transport system, permease
BG574_06080	COG4172	Belongs to the ABC transporter superfamily
BG574_06085	COG5645	(Lipo)protein
BG574_06100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG574_06110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG574_06130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BG574_06140	COG0589	response to stress
BG574_06150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BG574_06155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG574_06165	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BG574_06175	COG2814	Major facilitator Superfamily
BG574_06180	COG2814	Major facilitator Superfamily
BG574_06185	COG3083	sulfuric ester hydrolase activity
BG574_06195	COG1309	transcriptional regulator
BG574_06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG574_06205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG574_06215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG574_06230	COG3105	Protein conserved in bacteria
BG574_06235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BG574_06245	COG3022	response to hydroperoxide
BG574_06260	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BG574_06270	COG0778	Nitroreductase
BG574_06280	COG0072	phenylalanine-tRNA ligase activity
BG574_06290	COG0791	NLP P60 protein
BG574_06295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG574_06300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BG574_06305	COG0539	negative regulation of cytoplasmic translation
BG574_06315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BG574_06320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BG574_06325	COG0284	orotidine-5'-phosphate decarboxylase activity
BG574_06330	COG0023	Translation Initiation Factor
BG574_06335	COG0741	lytic transglycosylase activity
BG574_06350	COG0779	Required for maturation of 30S ribosomal subunits
BG574_06355	COG0195	Participates in both transcription termination and antitermination
BG574_06360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BG574_06365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BG574_06370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BG574_06375	COG2951	lytic endotransglycosylase activity
BG574_06380	COG0590	tRNA wobble adenosine to inosine editing
BG574_06385	COG0513	Belongs to the DEAD box helicase family
BG574_06390	COG4785	May be involved in cell division
BG574_06400	COG5002	protein histidine kinase activity
BG574_06405	COG0745	RESPONSE REGULATOR receiver
BG574_06430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG574_06435	COG0527	aspartate kinase activity
BG574_06440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_06440	COG1263	PTS System
BG574_06440	COG2190	(PTS) system
BG574_06445	COG2926	Belongs to the UPF0265 family
BG574_06450	COG0248	Ppx GppA phosphatase
BG574_06455	COG2731	YhcH YjgK YiaL family protein
BG574_06460	COG1737	Transcriptional regulator
BG574_06465	COG2801	Transposase and inactivated derivatives
BG574_06470	COG0737	Belongs to the 5'-nucleotidase family
BG574_06475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BG574_06480	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BG574_06485	COG0658	competence protein
BG574_06485	COG2333	competence protein COMEC
BG574_06500	COG2831	hemolysin activation secretion protein
BG574_06505	COG3210	domain, Protein
BG574_06555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG574_06560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG574_06565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG574_06570	COG1136	(ABC) transporter
BG574_06570	COG0577	efflux transmembrane transporter activity
BG574_06580	COG3956	TIGRFAM MazG family protein
BG574_06590	COG0285	dihydrofolate synthase activity
BG574_06595	COG1448	Aminotransferase
BG574_06605	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BG574_06610	COG0314	molybdopterin synthase activity
BG574_06615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BG574_06620	COG0315	cyclic pyranopterin monophosphate synthase activity
BG574_06630	COG2909	trisaccharide binding
BG574_06635	COG3005	denitrification pathway
BG574_06640	COG0243	molybdopterin cofactor binding
BG574_06655	COG2801	Transposase and inactivated derivatives
BG574_06665	COG0372	Belongs to the citrate synthase family
BG574_06670	COG0538	isocitrate dehydrogenase activity
BG574_06675	COG1049	propionate catabolic process, 2-methylcitrate cycle
BG574_06680	COG0243	molybdopterin cofactor binding
BG574_06690	COG2363	Small membrane protein
BG574_06715	COG0626	cystathionine gamma-synthase activity
BG574_06745	COG0737	Belongs to the 5'-nucleotidase family
BG574_06755	COG0857	belongs to the CobB CobQ family
BG574_06755	COG0280	phosphate acetyltransferase
BG574_06760	COG0288	reversible hydration of carbon dioxide
BG574_06765	COG0028	Belongs to the TPP enzyme family
BG574_06770	COG0440	acetolactate synthase activity
BG574_06775	COG0697	spore germination
BG574_06780	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BG574_06780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG574_06790	COG0006	proline dipeptidase activity
BG574_06800	COG1494	fructose-1,6-bisphosphatase
BG574_06805	COG3074	FtsZ-dependent cytokinesis
BG574_06810	COG1435	thymidine kinase activity
BG574_06815	COG0641	radical SAM
BG574_06820	COG3119	arylsulfatase activity
BG574_06825	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG574_06830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG574_06835	COG0730	response to heat
BG574_06840	COG1214	PFAM Peptidase M22, glycoprotease
BG574_06845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BG574_06850	COG2321	neutral zinc metallopeptidase
BG574_06855	COG1674	ftsk spoiiie
BG574_06860	COG1522	sequence-specific DNA binding
BG574_06865	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BG574_06870	COG1940	carbohydrate kinase activity
BG574_06870	COG1846	Transcriptional regulator
BG574_06875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BG574_06880	COG3036	rescue of stalled ribosome
BG574_06885	COG2226	methyltransferase
BG574_06900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG574_06905	COG0583	DNA-binding transcription factor activity
BG574_06920	COG2969	positive regulation of protein catabolic process
BG574_06925	COG0625	glutathione transferase activity
BG574_06930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG574_06940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BG574_06950	COG0556	nucleotide-excision repair
BG574_06965	COG2837	iron assimilation
BG574_06975	COG0613	PHP domain protein
BG574_06985	COG2925	Exonuclease
BG574_06990	COG0017	Asparaginyl-tRNA synthetase
BG574_06995	COG1509	lysine 2,3-aminomutase activity
BG574_07005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BG574_07025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG574_07035	COG2271	Major facilitator Superfamily
BG574_07040	COG1085	galactose-1-phosphate uridylyltransferase
BG574_07045	COG2211	Major facilitator Superfamily
BG574_07055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG574_07060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG574_07070	COG0251	oxidation-reduction process
BG574_07100	COG4409	exo-alpha-(2->6)-sialidase activity
BG574_07105	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BG574_07110	COG0312	modulator of DNA gyrase
BG574_07115	COG3028	Belongs to the UPF0307 family
BG574_07125	COG1811	Na channel or pump
BG574_07135	COG3787	Belongs to the UPF0306 family
BG574_07165	COG3945	hemerythrin HHE cation binding domain
BG574_07180	COG1278	Cold shock
BG574_07185	COG0697	spore germination
BG574_07205	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG574_07210	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG574_07220	COG2391	methyltransferase activity
BG574_07225	COG0425	Belongs to the sulfur carrier protein TusA family
BG574_07245	COG3676	manually curated
BG574_07255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BG574_07260	COG3100	YcgL domain-containing protein
BG574_07265	COG0305	Participates in initiation and elongation during chromosome replication
BG574_07270	COG4607	ABC-type enterochelin transport system periplasmic component
BG574_07275	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG574_07280	COG4605	iron ion homeostasis
BG574_07285	COG4604	ABC transporter, ATP-binding protein
BG574_07300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BG574_07305	COG1392	Phosphate transport regulator
BG574_07310	COG0306	phosphate transporter
BG574_07315	COG4991	sh3 domain protein
BG574_07335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG574_07340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BG574_07345	COG3676	manually curated
BG574_07350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BG574_07375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG574_07380	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG574_07385	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BG574_07390	COG0167	dihydroorotate dehydrogenase activity
BG574_07395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG574_07410	COG1132	(ABC) transporter
BG574_07415	COG1346	cytolysis
BG574_07420	COG1380	Effector of murein hydrolase LrgA
BG574_07425	COG1199	ATP-dependent helicase activity
BG574_07435	COG1122	ATPase activity
BG574_07445	COG0659	secondary active sulfate transmembrane transporter activity
BG574_07450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG574_07455	COG0629	single-stranded DNA binding
BG574_07470	COG2801	Transposase and inactivated derivatives
BG574_07475	COG0676	glucose-6-phosphate 1-epimerase activity
BG574_07485	COG1763	Mo-molybdopterin cofactor biosynthetic process
BG574_07490	COG3084	Protein conserved in bacteria
BG574_07495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG574_07500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG574_07505	COG3691	Protein conserved in bacteria
BG574_07510	COG2801	Transposase and inactivated derivatives
BG574_07530	COG0305	Participates in initiation and elongation during chromosome replication
BG574_07555	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BG574_07570	COG1286	toxin biosynthetic process
BG574_07575	COG0328	RNA-DNA hybrid ribonuclease activity
BG574_07585	COG0859	PFAM glycosyl transferase family 9
BG574_07590	COG0463	Glycosyl transferase, family 2
BG574_07595	COG1534	Rna-binding protein
BG574_07600	COG0671	phosphoesterase, PA-phosphatase related
BG574_07615	COG1368	sulfuric ester hydrolase activity
BG574_07620	COG0633	Ferredoxin
BG574_07620	COG3217	Mosc domain protein beta barrel domain protein
BG574_07625	COG1722	exodeoxyribonuclease VII activity
BG574_07630	COG0142	geranyltranstransferase activity
BG574_07635	COG0121	glutamine amidotransferase
BG574_07640	COG3676	manually curated
BG574_07645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG574_07650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG574_07655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BG574_07660	COG1792	Involved in formation and maintenance of cell shape
BG574_07665	COG1077	Cell shape determining protein MreB Mrl
BG574_07675	COG0572	uridine kinase
BG574_07680	COG0717	Belongs to the dCTP deaminase family
BG574_07690	COG0586	Pfam SNARE associated Golgi protein
BG574_07700	COG2226	methyltransferase
BG574_07705	COG0596	Alpha beta hydrolase
BG574_07715	COG0318	PFAM AMP-dependent synthetase and ligase
BG574_07720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BG574_07720	COG3264	Mechanosensitive ion channel
BG574_07730	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BG574_07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG574_07740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG574_07750	COG0582	viral genome integration into host DNA
BG574_07755	COG0582	viral genome integration into host DNA
BG574_07820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG574_07825	COG0583	DNA-binding transcription factor activity
BG574_07830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BG574_07835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BG574_07840	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BG574_07845	COG0058	SHG alpha-glucan phosphorylase activity
BG574_07860	COG1523	belongs to the glycosyl hydrolase 13 family
BG574_07865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BG574_07870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_07870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_07875	COG1105	Belongs to the carbohydrate kinase PfkB family
BG574_07880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BG574_07880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG574_07880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG574_07895	COG1704	LemA family
BG574_07920	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BG574_07930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BG574_07940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG574_07945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BG574_07950	COG0575	Belongs to the CDS family
BG574_07955	COG0750	zinc metalloprotease
BG574_07970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG574_07975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG574_07980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG574_07985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG574_07985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BG574_07990	COG0134	indole-3-glycerol-phosphate synthase activity
BG574_07990	COG0135	phosphoribosylanthranilate isomerase activity
BG574_07995	COG3098	single-species biofilm formation
BG574_08000	COG0564	pseudouridine synthase activity
BG574_08010	COG3025	triphosphatase activity
BG574_08015	COG3106	COG3106 Predicted ATPase
BG574_08030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BG574_08050	COG0495	leucyl-tRNA aminoacylation
BG574_08055	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BG574_08060	COG1466	dna polymerase III delta subunit
BG574_08065	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BG574_08070	COG0237	dephospho-CoA kinase activity
BG574_08070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BG574_08080	COG1459	type II secretion system
BG574_08085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG574_08090	COG4969	Belongs to the N-Me-Phe pilin family
BG574_08095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BG574_08105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BG574_08110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BG574_08115	COG0730	response to heat
BG574_08120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG574_08125	COG0617	tRNA 3'-terminal CCA addition
BG574_08130	COG1275	C4-dicarboxylate transporter malic acid transport protein
BG574_08135	COG2975	iron-sulfur cluster assembly
BG574_08140	COG0633	Ferredoxin
BG574_08155	COG2852	Protein conserved in bacteria
BG574_08165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BG574_08175	COG0822	iron-sulfur transferase activity
BG574_08185	COG1959	2 iron, 2 sulfur cluster binding
BG574_08195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG574_08200	COG5002	protein histidine kinase activity
BG574_08200	COG0784	Response regulator, receiver
BG574_08200	COG2198	Histidine kinase
BG574_08210	COG0697	spore germination
BG574_08220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG574_08225	COG2840	Smr protein MutS2
BG574_08235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BG574_08250	COG2801	Transposase and inactivated derivatives
BG574_08260	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BG574_08265	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BG574_08265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BG574_08270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG574_08275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG574_08285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG574_08290	COG4166	transmembrane transport
BG574_08300	COG0444	Belongs to the ABC transporter superfamily
BG574_08305	COG4172	Belongs to the ABC transporter superfamily
BG574_08310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BG574_08325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG574_08335	COG1160	GTP binding
BG574_08340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BG574_08340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BG574_08345	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BG574_08350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG574_08355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BG574_08360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BG574_08365	COG0318	PFAM AMP-dependent synthetase and ligase
BG574_08375	COG3026	antisigma factor binding
BG574_08380	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BG574_08385	COG1595	DNA-templated transcription, initiation
BG574_08395	COG0561	phosphatase activity
BG574_08400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG574_08405	COG0385	Bile acid
BG574_08410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BG574_08425	COG1074	ATP-dependent DNA helicase activity
BG574_08430	COG0534	Mate efflux family protein
BG574_08435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG574_08455	COG1643	Atp-dependent helicase
BG574_08470	COG0330	HflC and HflK could
BG574_08475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BG574_08485	COG2932	Transcriptional regulator
BG574_08490	COG0791	NLP P60 protein
BG574_08500	COG3381	protein complex oligomerization
BG574_08510	COG2801	Transposase and inactivated derivatives
BG574_08525	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BG574_08550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BG574_08555	COG0583	DNA-binding transcription factor activity
BG574_08580	COG1702	phosphate starvation-inducible protein PhoH
BG574_08595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG574_08600	COG0626	cystathionine gamma-synthase activity
BG574_08615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BG574_08620	COG3023	N-Acetylmuramoyl-L-alanine amidase
BG574_08625	COG0564	pseudouridine synthase activity
BG574_08650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BG574_08655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG574_08660	COG2814	Major facilitator Superfamily
BG574_08670	COG1441	menaquinone biosynthetic process
BG574_08685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG574_08690	COG2027	D-alanyl-D-alanine carboxypeptidase
BG574_08705	COG1760	l-serine dehydratase
BG574_08710	COG0814	amino acid
BG574_08715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG574_08720	COG1560	Kdo2-lipid A biosynthetic process
BG574_08725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG574_08735	COG0564	pseudouridine synthase activity
BG574_08740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG574_08755	COG1965	Belongs to the frataxin family
BG574_08765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BG574_08770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BG574_08775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BG574_08790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG574_08795	COG0670	Belongs to the BI1 family
BG574_08800	COG2920	part of a sulfur-relay system
BG574_08810	COG2190	(PTS) system
BG574_08810	COG1263	PTS System
BG574_08810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG574_08825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG574_08830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG574_08835	COG2801	Transposase and inactivated derivatives
BG574_08845	COG1584	GPR1 FUN34 yaaH family protein
BG574_08865	COG0861	Integral membrane protein TerC family
BG574_08870	COG1472	Belongs to the glycosyl hydrolase 3 family
BG574_08875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG574_08895	COG2801	Transposase and inactivated derivatives
BG574_08900	COG0277	FAD linked oxidase domain protein
BG574_08930	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BG574_08955	COG3299	homolog of phage Mu protein gp47
BG574_09025	COG4397	Mu-like prophage major head subunit gpT
BG574_09040	COG5005	Phage virion morphogenesis
BG574_09045	COG2369	cell adhesion
BG574_09050	COG4383	Mu-like prophage protein gp29
BG574_09060	COG2801	Transposase and inactivated derivatives
BG574_09115	COG5301	cellulose 1,4-beta-cellobiosidase activity
BG574_09180	COG3723	Recombinational DNA repair protein, rece pathway
BG574_09305	COG3179	chitinase
BG574_09320	COG5410	chromosome segregation
BG574_09420	COG2801	Transposase and inactivated derivatives
BG574_09475	COG3561	AntA/AntB antirepressor
BG574_09480	COG4382	Mu-like prophage protein Gp16
BG574_09505	COG4396	Host-nuclease inhibitor protein Gam
BG574_09535	COG2842	Transposition protein
BG574_09545	COG3423	Transcriptional regulator
BG574_09550	COG2932	Transcriptional regulator
BG574_09555	COG0148	phosphopyruvate hydratase activity
BG574_09560	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
BG574_09570	COG2233	PERMEase
BG574_09575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG574_09585	COG0709	Synthesizes selenophosphate from selenide and ATP
BG574_09605	COG2801	Transposase and inactivated derivatives
BG574_09615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BG574_09640	COG1408	metallophosphoesterase
BG574_09645	COG3739	integral membrane protein
BG574_09650	COG1085	galactose-1-phosphate uridylyltransferase
BG574_09655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BG574_09660	COG2017	converts alpha-aldose to the beta-anomer
BG574_09665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BG574_09670	COG1862	Preprotein translocase
BG574_09675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG574_09680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG574_09685	COG2252	PERMEase
BG574_09700	COG1840	ABC-type Fe3 transport system, periplasmic component
BG574_09705	COG1252	NADH dehydrogenase
BG574_09715	COG3719	Belongs to the RNase T2 family
BG574_09725	COG4667	esterase of the alpha-beta hydrolase superfamily
BG574_09755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BG574_09760	COG3593	DNA synthesis involved in DNA repair
BG574_09765	COG1611	Belongs to the LOG family
BG574_09770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BG574_09790	COG0732	type I restriction modification DNA specificity domain
BG574_09800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG574_09810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BG574_09865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG574_09870	COG1538	Outer membrane efflux protein
BG574_09875	COG0194	GDP metabolic process
BG574_09880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BG574_09895	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG574_09905	COG2914	Belongs to the UPF0125 (RnfH) family
BG574_09910	COG2867	negative regulation of translational initiation
BG574_09915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BG574_09920	COG4149	molybdate abc transporter
BG574_09925	COG0725	ABC transporter, periplasmic molybdate-binding protein
BG574_09930	COG0842	Transport permease protein
BG574_09935	COG1131	(ABC) transporter
BG574_09940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG574_09945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG574_09950	COG1560	Kdo2-lipid A biosynthetic process
BG574_09955	COG4660	Part of a membrane complex involved in electron transport
BG574_09965	COG4658	electron transport chain
BG574_09970	COG2860	membrane
BG574_09975	COG4656	Part of a membrane complex involved in electron transport
BG574_09980	COG2878	Part of a membrane complex involved in electron transport
BG574_09985	COG4657	Part of a membrane complex involved in electron transport
BG574_10005	COG0488	(ABC) transporter
BG574_10025	COG2965	DNA replication, synthesis of RNA primer
BG574_10050	COG1640	4-alpha-glucanotransferase
BG574_10065	COG3273	potassium ion transport
BG574_10065	COG0471	metal ion transport
BG574_10070	COG1187	pseudouridine synthase activity
BG574_10075	COG0009	L-threonylcarbamoyladenylate synthase
BG574_10080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BG574_10085	COG0512	Glutamine amidotransferase of anthranilate synthase
BG574_10090	COG1942	4-Oxalocrotonate Tautomerase
BG574_10100	COG2226	methyltransferase
BG574_10110	COG2166	iron-sulfur cluster assembly
BG574_10115	COG0740	serine-type endopeptidase activity
BG574_10120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BG574_10145	COG1663	tetraacyldisaccharide 4'-kinase activity
BG574_10165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BG574_10170	COG4206	TonB-dependent receptor
BG574_10185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG574_10190	COG1120	ATPase activity
BG574_10220	COG2814	Major facilitator Superfamily
BG574_10225	COG1120	ATPase activity
BG574_10240	COG2801	Transposase and inactivated derivatives
BG574_10250	COG4773	Receptor
BG574_10260	COG2801	Transposase and inactivated derivatives
BG574_10265	COG2268	Band 7 protein
BG574_10270	COG2841	Protein conserved in bacteria
BG574_10275	COG1605	Chorismate mutase
BG574_10275	COG0077	Prephenate dehydratase
BG574_10280	COG0339	signal peptide processing
BG574_10285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG574_10295	COG1882	Formate acetyltransferase
BG574_10300	COG2116	formate transmembrane transporter activity
BG574_10305	COG1238	metal cluster binding
BG574_10310	COG0501	Belongs to the peptidase M48B family
BG574_10320	COG2431	L-lysine efflux transmembrane transporter activity
BG574_10345	COG0494	nUDIX hydrolase
BG574_10360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BG574_10365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BG574_10370	COG5007	Belongs to the BolA IbaG family
BG574_10380	COG2854	intermembrane phospholipid transfer
BG574_10385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BG574_10390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BG574_10395	COG1127	ABC transporter
BG574_10400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG574_10410	COG3088	subunit of a heme lyase
BG574_10410	COG4235	cytochrome complex assembly
BG574_10415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG574_10420	COG1138	Cytochrome C-type biogenesis protein
BG574_10425	COG3301	Polysulphide reductase, NrfD
BG574_10430	COG0437	4 iron, 4 sulfur cluster binding
BG574_10435	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BG574_10450	COG3978	acetolactate synthase activity
BG574_10470	COG0477	Major facilitator Superfamily
BG574_10490	COG0616	signal peptide processing
BG574_10495	COG0778	Nitroreductase
BG574_10500	COG2183	response to ionizing radiation
BG574_10505	COG3063	Type IV pilus biogenesis stability protein PilW
BG574_10530	COG1121	(ABC) transporter
BG574_10535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG574_10540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG574_10545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG574_10570	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG574_10575	COG1487	ribonuclease activity
BG574_10595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG574_10600	COG0814	amino acid
BG574_10620	COG0748	coenzyme F420 binding
BG574_10625	COG0308	aminopeptidase N
BG574_10630	COG1254	Belongs to the acylphosphatase family
BG574_10635	COG4166	transmembrane transport
BG574_10655	COG5413	integral membrane protein
BG574_10660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG574_10670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG574_10685	COG1187	pseudouridine synthase activity
BG574_10695	COG3030	protein affecting phage T7 exclusion by the F plasmid
BG574_10700	COG0006	proline dipeptidase activity
BG574_10710	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BG574_10760	COG1793	dna ligase
BG574_10765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BG574_10770	COG1984	allophanate hydrolase subunit 2
BG574_10775	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BG574_10780	COG1914	H( )-stimulated, divalent metal cation uptake system
BG574_10785	COG3630	sodium ion export across plasma membrane
BG574_10790	COG5016	pyruvate
BG574_10790	COG0511	ligase activity, forming carbon-carbon bonds
BG574_10795	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BG574_10800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG574_10810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG574_10825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BG574_10835	COG2197	response regulator
BG574_10840	COG1609	Transcriptional regulator
BG574_10845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG574_10850	COG1879	ABC-type sugar transport system periplasmic component
BG574_10855	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG574_10870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BG574_10875	COG0354	folic acid binding
BG574_10880	COG1561	YicC-like family, N-terminal region
BG574_10895	COG1556	Lactate utilization protein
BG574_10900	COG1139	Iron-sulfur cluster binding protein
BG574_10905	COG0247	lactate metabolic process
BG574_10910	COG1620	l-lactate permease
BG574_10925	COG1686	Belongs to the peptidase S11 family
BG574_10935	COG0747	negative chemotaxis
BG574_10940	COG0601	transmembrane transport
BG574_10945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG574_10950	COG4172	Belongs to the ABC transporter superfamily
BG574_10955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG574_10960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG574_10970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BG574_10975	COG0196	riboflavin kinase activity
BG574_10980	COG3172	ATPase kinase involved in NAD metabolism
BG574_10985	COG2129	metallophosphoesterase
BG574_10990	COG0745	RESPONSE REGULATOR receiver
BG574_11000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG574_11005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BG574_11010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG574_11020	COG1047	Peptidyl-prolyl cis-trans
BG574_11025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG574_11035	COG1720	tRNA m6t6A37 methyltransferase activity
BG574_11040	COG1575	Belongs to the MenA family. Type 1 subfamily
BG574_11050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG574_11070	COG3307	-O-antigen
BG574_11075	COG3307	-O-antigen
BG574_11090	COG0562	UDP-galactopyranose mutase
BG574_11115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BG574_11130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG574_11135	COG1758	RNA polymerase activity
BG574_11150	COG1621	beta-fructofuranosidase activity
BG574_11155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG574_11160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG574_11165	COG2190	(PTS) system
BG574_11170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG574_11175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG574_11180	COG1178	ABC-type Fe3 transport system permease component
BG574_11185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BG574_11195	COG0024	Methionine aminopeptidase
BG574_11200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BG574_11210	COG0676	glucose-6-phosphate 1-epimerase activity
BG574_11215	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BG574_11225	COG2932	Transcriptional regulator
BG574_11230	COG3423	Transcriptional regulator
BG574_11235	COG2801	Transposase and inactivated derivatives
BG574_11240	COG0513	Belongs to the DEAD box helicase family
BG574_11245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG574_11250	COG0733	neurotransmitter:sodium symporter activity
BG574_11255	COG4536	flavin adenine dinucleotide binding
BG574_11260	COG4137	Cytochrome C assembly protein
BG574_11265	COG1399	metal-binding, possibly nucleic acid-binding protein
BG574_11270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BG574_11275	COG0416	fatty acid biosynthetic process
BG574_11290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BG574_11295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BG574_11300	COG2995	paraquat-inducible protein a
BG574_11305	COG1943	Transposase
BG574_11310	COG1289	transmembrane transporter activity
BG574_11315	COG1803	Methylglyoxal synthase
BG574_11320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BG574_11325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG574_11325	COG0678	peroxiredoxin activity
BG574_11330	COG0583	DNA-binding transcription factor activity
BG574_11335	COG1309	transcriptional regulator
BG574_11350	COG2801	Transposase and inactivated derivatives
BG574_11365	COG0494	nUDIX hydrolase
BG574_11370	COG0730	response to heat
BG574_11380	COG0546	phosphoglycolate phosphatase activity
BG574_11395	COG0180	Tryptophanyl-tRNA synthetase
BG574_11400	COG0501	Belongs to the peptidase M48B family
BG574_11405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BG574_11425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BG574_11430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BG574_11435	COG0470	DNA polymerase III
BG574_11450	COG0084	hydrolase, TatD family'
BG574_11460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG574_11465	COG1215	transferase activity, transferring glycosyl groups
BG574_11505	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BG574_11520	COG0174	glutamine synthetase
BG574_11525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BG574_11535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BG574_11545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG574_11570	COG0085	RNA polymerase activity
BG574_11585	COG2168	tRNA wobble position uridine thiolation
BG574_11595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BG574_11600	COG2964	Protein conserved in bacteria
BG574_11605	COG0545	Peptidyl-prolyl cis-trans isomerase
BG574_11610	COG2900	Belongs to the SlyX family
BG574_11620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG574_11625	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BG574_11635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG574_11640	COG1328	CTP reductase activity
BG574_11655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BG574_11665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG574_11675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG574_11680	COG1028	Short-chain dehydrogenase reductase Sdr
BG574_11695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG574_11710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BG574_11720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG574_11740	COG0758	DNA mediated transformation
BG574_11755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG574_11760	COG1067	ATP-dependent peptidase activity
BG574_11765	COG3120	sequence-specific DNA binding
BG574_11775	COG0277	FAD linked oxidase domain protein
BG574_11775	COG0247	lactate metabolic process
BG574_11780	COG2050	protein possibly involved in aromatic compounds catabolism
BG574_11795	COG0204	Acyl-transferase
BG574_11805	COG0825	malonyl-CoA metabolic process
BG574_11830	COG2801	Transposase and inactivated derivatives
BG574_11840	COG0235	Class ii aldolase
BG574_11845	COG3623	hexulose-6-phosphate isomerase
BG574_11865	COG0737	Belongs to the 5'-nucleotidase family
BG574_11885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG574_11890	COG1929	Belongs to the glycerate kinase type-1 family
BG574_11895	COG2610	gluconate transmembrane transporter activity
BG574_11900	COG3835	regulator
BG574_11915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BG574_11920	COG0840	transmembrane signaling receptor activity
BG574_11945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BG574_11955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BG574_11965	COG0089	rRNA binding
BG574_11970	COG0088	Forms part of the polypeptide exit tunnel
BG574_11975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BG574_11980	COG0051	transcription antitermination factor activity, RNA binding
BG574_11985	COG3070	regulator of competence-specific genes
BG574_11995	COG0019	diaminopimelate decarboxylase activity
BG574_12000	COG0625	glutathione transferase activity
BG574_12010	COG2264	protein methyltransferase activity
BG574_12055	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BG574_12060	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BG574_12065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BG574_12070	COG1053	succinate dehydrogenase
BG574_12075	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BG574_12080	COG2962	Rard protein
BG574_12085	COG2223	nitrite transmembrane transporter activity
BG574_12090	COG2223	nitrite transmembrane transporter activity
BG574_12095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG574_12100	COG2020	methyltransferase activity
BG574_12105	COG0728	peptidoglycan biosynthetic process
BG574_12110	COG0268	Binds directly to 16S ribosomal RNA
BG574_12115	COG1970	mechanosensitive ion channel activity
BG574_12120	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BG574_12125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG574_12130	COG1739	Uncharacterized protein family UPF0029
BG574_12140	COG1119	ATPase activity
BG574_12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG574_12155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BG574_12170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BG574_12175	COG0321	lipoyl(octanoyl) transferase activity
BG574_12180	COG2921	Belongs to the UPF0250 family
BG574_12185	COG1686	Belongs to the peptidase S11 family
BG574_12190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BG574_12195	COG0772	Belongs to the SEDS family
BG574_12200	COG0768	penicillin binding
BG574_12210	COG0799	negative regulation of ribosome biogenesis
BG574_12220	COG1312	Catalyzes the dehydration of D-mannonate
BG574_12225	COG2186	Transcriptional regulator
BG574_12230	COG1028	Short-chain dehydrogenase reductase Sdr
BG574_12245	COG2211	Major facilitator Superfamily
BG574_12260	COG0800	Aldolase
BG574_12285	COG0545	Peptidyl-prolyl cis-trans isomerase
BG574_12290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG574_12305	COG0037	tRNA processing
BG574_12310	COG4974	Belongs to the 'phage' integrase family
BG574_12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG574_12370	COG3133	Outer membrane lipoprotein
BG574_12375	COG3102	Protein conserved in bacteria
BG574_12380	COG0018	arginyl-trna synthetase
BG574_12385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG574_12395	COG1138	Cytochrome C-type biogenesis protein
BG574_12405	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG574_12410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG574_12415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG574_12420	COG4133	protoheme IX ABC transporter activity
BG574_12425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BG574_12430	COG0747	negative chemotaxis
BG574_12435	COG0601	transmembrane transport
BG574_12440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG574_12445	COG0444	Belongs to the ABC transporter superfamily
BG574_12450	COG4608	Belongs to the ABC transporter superfamily
BG574_12465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG574_12465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG574_12470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG574_12475	COG2801	Transposase and inactivated derivatives
BG574_12480	COG0616	signal peptide processing
BG574_12495	COG2801	Transposase and inactivated derivatives
BG574_12530	COG3161	chorismate lyase activity
BG574_12540	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BG574_12555	COG0442	prolyl-tRNA aminoacylation
BG574_12580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG574_12585	COG1957	nucleoside hydrolase
BG574_12590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG574_12595	COG1192	Involved in chromosome partitioning
BG574_12625	COG3676	manually curated
BG574_12655	COG3012	SEC-C Motif Domain Protein