locus-tag	class	description
MsedC_0003	ENOG4105NAU	thioesterase Superfamily protein
MsedC_0007	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MsedC_0011	ENOG4105C7B	Threonine dehydratase
MsedC_0012	ENOG4105CQC	Prephenate dehydratase
MsedC_0015	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
MsedC_0018	ENOG4105C83	adenylosuccinate lyase
MsedC_0021	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MsedC_0022	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
MsedC_0024	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
MsedC_0025	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MsedC_0026	ENOG4105KG3	cytidine deaminase
MsedC_0027	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
MsedC_0030	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
MsedC_0031	ENOG4105C6K	Malic enzyme
MsedC_0033	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MsedC_0034	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MsedC_0035	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MsedC_0036	ENOG4105XPM	ribosomal protein
MsedC_0037	ENOG4105CHV	Transcription elongation factor NusA
MsedC_0040	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
MsedC_0041	ENOG4107QK2	May be the GTPase, regulating ATP sulfurylase activity (By similarity)
MsedC_0042	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
MsedC_0044	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
MsedC_0047	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
MsedC_0051	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
MsedC_0055	ENOG4107QRT	dEAD DEAH box helicase
MsedC_0057	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MsedC_0058	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MsedC_0059	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
MsedC_0070	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
MsedC_0071	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
MsedC_0073	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MsedC_0083	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
MsedC_0088	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MsedC_0089	ENOG4107YBY	Hydrolase
MsedC_0092	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
MsedC_0093	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
MsedC_0095	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
MsedC_0098	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MsedC_0099	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
MsedC_0100	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
MsedC_0101	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
MsedC_0102	ENOG4108FGF	50s ribosomal protein l29
MsedC_0105	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
MsedC_0106	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
MsedC_0108	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MsedC_0109	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
MsedC_0114	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
MsedC_0116	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
MsedC_0121	ENOG4105CAT	Cytidine monophosphate kinase
MsedC_0134	ENOG41088YS	Glycosyl transferase (Group 1
MsedC_0150	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
MsedC_0151	ENOG4108Z1Z	gCN5-related N-acetyltransferase
MsedC_0154	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
MsedC_0157	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
MsedC_0158	ENOG4105DHP	deoxycytidine triphosphate deaminase
MsedC_0161	ENOG4105NBF	ammecr1 domain protein
MsedC_0171	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
MsedC_0172	ENOG4107U4Q	acetylglutamate kinase
MsedC_0175	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MsedC_0176	ENOG4105C8Y	Acetylornithine aminotransferase
MsedC_0178	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
MsedC_0189	ENOG4108JJB	ABC transporter
MsedC_0190	ENOG4105EN6	Membrane
MsedC_0195	ENOG4105DWF	phosphomethylpyrimidine kinase
MsedC_0196	ENOG4108RVA	ribokinase
MsedC_0197	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
MsedC_0207	ENOG4105CPQ	Dehydrogenase
MsedC_0208	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
MsedC_0210	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
MsedC_0211	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MsedC_0215	ENOG4105C5S	asparaginyl-tRNA synthetase
MsedC_0216	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
MsedC_0219	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MsedC_0222	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MsedC_0223	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
MsedC_0224	ENOG4105D52	delta-aminolevulinic acid dehydratase
MsedC_0225	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
MsedC_0226	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
MsedC_0231	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
MsedC_0232	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
MsedC_0236	ENOG4108VA3	3-hexulose-6-phosphate synthase
MsedC_0237	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
MsedC_0240	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
MsedC_0246	ENOG41080HJ	6-phospho 3-hexuloisomerase
MsedC_0247	ENOG41061GT	Aldolase
MsedC_0249	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MsedC_0251	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
MsedC_0252	ENOG4105D0M	Protease HtpX homolog
MsedC_0253	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
MsedC_0256	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
MsedC_0262	ENOG4105CJ1	ABC, transporter
MsedC_0267	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
MsedC_0277	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MsedC_0282	ENOG4105C1G	acyl-Coa dehydrogenase
MsedC_0283	ENOG4107YAU	phenylacetic acid degradation protein
MsedC_0284	ENOG4105C1G	acyl-Coa dehydrogenase
MsedC_0285	ENOG4105C8Y	Acetylornithine aminotransferase
MsedC_0286	ENOG4105C1G	acyl-Coa dehydrogenase
MsedC_0288	ENOG4105DXD	2-methylcitrate dehydratase
MsedC_0289	ENOG4105CR4	methylisocitrate lyase
MsedC_0290	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MsedC_0291	ENOG4105BZN	citrate synthase
MsedC_0300	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MsedC_0301	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MsedC_0305	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
MsedC_0306	ENOG4108RAC	Rubrerythrin
MsedC_0316	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
MsedC_0317	ENOG4105EJ5	oxidoreductase gamma subunit
MsedC_0318	ENOG4105WGB	oxidoreductase, delta subunit
MsedC_0319	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
MsedC_0320	ENOG4105DDK	oxidoreductase, beta subunit
MsedC_0323	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MsedC_0333	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MsedC_0336	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MsedC_0345	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
MsedC_0348	ENOG4105CGU	Enoyl-CoA hydratase
MsedC_0354	ENOG4105VUC	UPF0237 protein
MsedC_0355	ENOG4105CAG	UPF0210 protein
MsedC_0356	ENOG4105CTD	carboxy-peptidase
MsedC_0357	ENOG4105CHR	reductase
MsedC_0365	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
MsedC_0371	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MsedC_0379	ENOG4105C26	Dehydrogenase
MsedC_0381	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
MsedC_0385	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
MsedC_0397	ENOG4105CGU	Enoyl-CoA hydratase
MsedC_0398	ENOG4105CHU	acetyl-coa acetyltransferase
MsedC_0400	ENOG4105DZS	Phenylacetate-CoA ligase
MsedC_0401	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MsedC_0406	ENOG4105CEY	Amp-dependent synthetase and ligase
MsedC_0407	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
MsedC_0408	ENOG4105CHU	acetyl-coa acetyltransferase
MsedC_0411	ENOG4105E39	Enoyl-CoA hydratase
MsedC_0412	ENOG4105C1G	acyl-Coa dehydrogenase
MsedC_0413	ENOG4105CEY	Amp-dependent synthetase and ligase
MsedC_0418	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MsedC_0420	ENOG4105CUB	amino acid
MsedC_0437	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
MsedC_0438	ENOG41079KZ	Major Facilitator Superfamily
MsedC_0440	ENOG4105CS1	NAD(P)H quinone oxidoreductase
MsedC_0442	ENOG4105D3W	isochorismatase
MsedC_0448	ENOG4105CQB	FAD linked oxidase domain protein
MsedC_0450	ENOG4105EE1	crotonyl-CoA reductase
MsedC_0451	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MsedC_0456	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MsedC_0458	ENOG4108JQ7	(ABC) transporter
MsedC_0464	ENOG4105CPC	Aldo Keto reductase
MsedC_0467	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
MsedC_0469	ENOG4107RGD	Major Facilitator superfamily
MsedC_0475	ENOG4105CSH	Transporter
MsedC_0476	ENOG4107TE1	transport protein
MsedC_0477	ENOG4105CPQ	Dehydrogenase
MsedC_0483	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MsedC_0499	ENOG41080XQ	Signal transduction protein with cbs domains
MsedC_0508	ENOG4105CYW	agmatinase
MsedC_0511	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MsedC_0516	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
MsedC_0519	ENOG4105WGB	oxidoreductase, delta subunit
MsedC_0520	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
MsedC_0521	ENOG4105DDK	oxidoreductase, beta subunit
MsedC_0522	ENOG4105C4X	radical SAM domain protein
MsedC_0523	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
MsedC_0532	ENOG4105CIG	ABC transporter
MsedC_0535	ENOG4105DQU	oxidoreductase, subunit beta
MsedC_0536	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
MsedC_0544	ENOG4105DGU	Histone deacetylase
MsedC_0545	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
MsedC_0553	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
MsedC_0556	ENOG4108I5C	dEAD DEAH box helicase
MsedC_0557	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
MsedC_0563	ENOG4105CQB	FAD linked oxidase domain protein
MsedC_0566	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
MsedC_0569	ENOG4105CEP	NADH dehydrogenase
MsedC_0570	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MsedC_0579	ENOG4105CJ1	ABC, transporter
MsedC_0581	ENOG4107RQ2	Cytochrome c oxidase, subunit I
MsedC_0584	ENOG4105C8T	Leucyl-tRNA synthetase
MsedC_0587	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MsedC_0592	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
MsedC_0594	ENOG4105CB5	ATP-dependent DNA helicase recG
MsedC_0608	ENOG4108RVA	ribokinase
MsedC_0609	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
MsedC_0611	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
MsedC_0613	ENOG4105C5F	glutamine synthetase
MsedC_0620	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MsedC_0623	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MsedC_0627	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
MsedC_0629	ENOG4105CJ1	ABC, transporter
MsedC_0635	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
MsedC_0641	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
MsedC_0645	ENOG4105ECY	inositol monophosphatase
MsedC_0646	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MsedC_0649	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
MsedC_0652	ENOG4106943	Heat shock protein
MsedC_0654	ENOG4105EM7	Selenocysteine-specific translation elongation factor
MsedC_0669	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MsedC_0673	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MsedC_0680	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
MsedC_0683	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
MsedC_0684	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
MsedC_0685	ENOG4105C28	cystathionine
MsedC_0688	ENOG4105E33	succinate dehydrogenase
MsedC_0689	ENOG4108J01	L-aspartate oxidase
MsedC_0693	ENOG4107QZT	geranylgeranyl reductase
MsedC_0697	ENOG4105D44	asparaginase
MsedC_0701	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
MsedC_0704	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MsedC_0706	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
MsedC_0712	ENOG4105KZX	Pterin carbinolamine dehydratase
MsedC_0715	ENOG4108HMX	isocitrate dehydrogenase (NADP)
MsedC_0721	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
MsedC_0723	ENOG4105C01	Dihydroxy-acid dehydratase
MsedC_0728	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
MsedC_0732	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
MsedC_0733	ENOG4105E50	uracil-dna glycosylase
MsedC_0734	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
MsedC_0736	ENOG4107JTW	chlorite dismutase
MsedC_0737	ENOG4107VIJ	nudix hydrolase
MsedC_0740	ENOG4107YU2	histidine triad (hIT) protein
MsedC_0741	ENOG4105D4A	Cell wall formation (By similarity)
MsedC_0744	ENOG410667J	hydrolase
MsedC_0746	ENOG4105PAD	Hydrolase
MsedC_0749	ENOG4108K7V	UPF0284 protein
MsedC_0751	ENOG4107EPV	Aminotransferase class V
MsedC_0754	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
MsedC_0757	ENOG4105CAY	ferredoxin--nadp reductase
MsedC_0763	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
MsedC_0769	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
MsedC_0770	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
MsedC_0771	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MsedC_0772	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
MsedC_0776	ENOG4107WZZ	SMC domain protein
MsedC_0781	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MsedC_0783	ENOG4105DU0	nucleoside hydrolase
MsedC_0786	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MsedC_0791	ENOG4105K63	Thioredoxin
MsedC_0802	ENOG4105C7Z	Conserved Protein
MsedC_0803	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
MsedC_0808	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
MsedC_0810	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
MsedC_0820	ENOG4108W0P	ABC transporter
MsedC_0821	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
MsedC_0829	ENOG4108JIG	Anaerobic dehydrogenase
MsedC_0830	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
MsedC_0845	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MsedC_0846	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MsedC_0848	ENOG4105D9P	serine threonine protein kinase
MsedC_0852	ENOG4105CJW	magnesium transporter
MsedC_0855	ENOG4105C5X	domain protein
MsedC_0864	ENOG4108JJB	ABC transporter
MsedC_0868	ENOG4105FCD	Major Facilitator
MsedC_0875	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MsedC_0876	ENOG4107RGD	Major Facilitator superfamily
MsedC_0882	ENOG4105C54	Major Facilitator superfamily
MsedC_0884	ENOG4105NTW	Transcriptional regulator
MsedC_0885	ENOG4108IUW	ABC transporter
MsedC_0890	ENOG4105CEU	Arginine dihydrolase
MsedC_0897	ENOG4105DQQ	Major facilitator superfamily MFS_1
MsedC_0898	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
MsedC_0900	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
MsedC_0903	ENOG4105CQM	Urea amidohydrolase subunit alpha
MsedC_0904	ENOG4108YZ9	Urea amidohydrolase subunit gamma
MsedC_0905	ENOG4105D5Q	Arginine ornithine antiporter
MsedC_0906	ENOG4105E8R	UPF0173 metal-dependent hydrolase
MsedC_0907	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MsedC_0908	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
MsedC_0922	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
MsedC_0928	ENOG4108IUM	Glycogen debranching enzyme
MsedC_0932	ENOG4108USZ	hydrogenase
MsedC_0939	ENOG4105DPX	Hydrogenase, large subunit
MsedC_0942	ENOG4105KVH	Transcriptional regulator
MsedC_0946	ENOG4105CQS	hydrogenase expression formation protein HypD
MsedC_0949	ENOG4105C45	hydrogenase expression formation protein (HypE)
MsedC_0954	ENOG4105C7Z	Conserved Protein
MsedC_0959	ENOG4105E3S	small subunit
MsedC_0970	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
MsedC_0975	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MsedC_0976	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
MsedC_0978	ENOG4107RIQ	Sulfate adenylate transferase
MsedC_0991	ENOG4105II7	pyrroline-5-carboxylate reductase
MsedC_0994	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
MsedC_1002	ENOG4105BZP	glycoside hydrolase 15-related
MsedC_1009	ENOG4105EFA	4-hydroxyphenylacetate
MsedC_1014	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MsedC_1016	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
MsedC_1018	ENOG4107YCR	Transcriptional regulator, ARSR family
MsedC_1020	ENOG4105CHR	reductase
MsedC_1024	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
MsedC_1025	ENOG4105D0M	Protease HtpX homolog
MsedC_1028	ENOG4105CEY	Amp-dependent synthetase and ligase
MsedC_1029	ENOG4105E4P	ATPase (AAA
MsedC_1035	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
MsedC_1041	ENOG4105D9P	serine threonine protein kinase
MsedC_1044	ENOG4107RBS	Methyltransferase
MsedC_1047	ENOG4108JJB	ABC transporter
MsedC_1052	ENOG4105CEP	NADH dehydrogenase
MsedC_1054	ENOG4105DAA	L-lactate
MsedC_1061	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MsedC_1062	ENOG4105C3U	ABC transporter
MsedC_1063	ENOG4108JQ7	(ABC) transporter
MsedC_1067	ENOG4105C6K	Malic enzyme
MsedC_1068	ENOG4105CSH	Transporter
MsedC_1069	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
MsedC_1070	ENOG4105JSC	dimethylmenaquinone methyltransferase
MsedC_1072	ENOG4108JQ1	Dehydrogenase
MsedC_1081	ENOG4105CIG	ABC transporter
MsedC_1086	ENOG4105EWK	phytoene
MsedC_1092	ENOG4105D3R	alkyl hydroperoxide reductase
MsedC_1104	ENOG4107QN2	dihydrolipoyl dehydrogenase
MsedC_1105	ENOG4105EUB	pirin domain protein
MsedC_1107	ENOG4105C54	Major Facilitator superfamily
MsedC_1109	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
MsedC_1110	ENOG4107TSN	permease
MsedC_1115	ENOG4105D1H	recombination factor protein RarA
MsedC_1126	ENOG4105E33	succinate dehydrogenase
MsedC_1130	ENOG4107GFK	fumarate
MsedC_1131	ENOG4106DSS	Tartrate dehydratase subunit alpha
MsedC_1132	ENOG4107QNK	)-transporter
MsedC_1133	ENOG4105CQB	FAD linked oxidase domain protein
MsedC_1134	ENOG4105C26	Dehydrogenase
MsedC_1138	ENOG4105DG4	malate L-lactate dehydrogenase
MsedC_1139	ENOG4105VP7	SAF domain protein
MsedC_1140	ENOG4105CTX	dehydratase
MsedC_1141	ENOG4105DIA	mandelate racemase muconate lactonizing
MsedC_1142	ENOG4105DRR	Transcriptional regulator, GntR family
MsedC_1144	ENOG4107U7N	hydantoinase B oxoprolinase
MsedC_1157	ENOG4105DTT	CRISPR-associated helicase, cas3
MsedC_1163	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
MsedC_1178	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
MsedC_1185	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
MsedC_1193	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
MsedC_1194	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
MsedC_1202	ENOG4105D64	Mechanosensitive ion channel
MsedC_1215	ENOG4108EHY	type IV secretion system
MsedC_1217	ENOG4105DDK	oxidoreductase, beta subunit
MsedC_1218	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
MsedC_1228	ENOG4105J0Q	Transcriptional regulator
MsedC_1229	ENOG4105KHC	sulfurtransferase
MsedC_1231	ENOG4105CPP	Dehydrogenase, E1 component
MsedC_1232	ENOG4107RUY	(E1 component), alpha subunit
MsedC_1236	ENOG4105CYC	Transferase
MsedC_1241	ENOG4105D2S	major facilitator superfamily
MsedC_1243	ENOG4105CEY	Amp-dependent synthetase and ligase
MsedC_1246	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
MsedC_1253	ENOG4105DA5	(ABC) transporter
MsedC_1267	ENOG4105C10	Electron transfer flavoprotein
MsedC_1270	ENOG4105C2X	Arabinose 5-phosphate isomerase
MsedC_1272	ENOG4105C57	major facilitator superfamily
MsedC_1274	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
MsedC_1287	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
MsedC_1297	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MsedC_1300	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
MsedC_1301	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
MsedC_1308	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MsedC_1309	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
MsedC_1316	ENOG4105C26	Dehydrogenase
MsedC_1320	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
MsedC_1322	ENOG4107YEI	lmbE family
MsedC_1323	ENOG4105D9G	High-affinity
MsedC_1327	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MsedC_1328	ENOG4106IPI	cyclase, family
MsedC_1332	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MsedC_1336	ENOG4108IEG	Formate dehydrogenase Alpha subunit
MsedC_1338	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
MsedC_1340	ENOG4105BZP	glycoside hydrolase 15-related
MsedC_1361	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
MsedC_1369	ENOG4105ETU	transcriptional activator (TenA
MsedC_1370	ENOG4106HK8	GPR1 FUN34 yaaH family protein
MsedC_1371	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MsedC_1372	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
MsedC_1376	ENOG4105ERH	Fumarylacetoacetate hydrolase
MsedC_1382	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MsedC_1384	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
MsedC_1392	ENOG4105CQR	helicase
MsedC_1393	ENOG4105D8K	carboxyl transferase
MsedC_1395	ENOG4105D7T	ABC transporter
MsedC_1396	ENOG4105C1J	atp-dependent rna helicase
MsedC_1398	ENOG4108JQ6	ABC transporter
MsedC_1405	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
MsedC_1406	ENOG4108R96	Methyltransferase, YaeB family
MsedC_1418	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
MsedC_1419	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
MsedC_1420	ENOG4105D1F	ATP-binding protein
MsedC_1422	ENOG4105KME	endoribonuclease L-psp
MsedC_1433	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
MsedC_1436	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
MsedC_1441	ENOG4105DZS	Phenylacetate-CoA ligase
MsedC_1442	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MsedC_1443	ENOG4107QPD	alcohol dehydrogenase
MsedC_1445	ENOG4105CPQ	Dehydrogenase
MsedC_1447	ENOG4108JPZ	Monovalent cation H antiporter subunit D
MsedC_1448	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1449	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1453	ENOG4105CGK	Exodeoxyribonuclease III
MsedC_1462	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MsedC_1468	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
MsedC_1469	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
MsedC_1471	ENOG4105CP7	Triose-phosphate isomerase
MsedC_1472	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
MsedC_1474	ENOG4105C5X	domain protein
MsedC_1475	ENOG4107QTZ	amino acid
MsedC_1476	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MsedC_1477	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
MsedC_1482	ENOG4105C9Q	fumarate hydratase class II
MsedC_1487	ENOG4107QM5	aconitate hydratase
MsedC_1494	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MsedC_1500	ENOG4105DF9	Lipoate-protein, ligase
MsedC_1501	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MsedC_1503	ENOG4107ZMQ	sugar fermentation stimulation protein
MsedC_1504	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MsedC_1508	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
MsedC_1511	ENOG4105HZM	Fha domain containing protein
MsedC_1528	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
MsedC_1530	ENOG4107SFF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
MsedC_1533	ENOG4105U0R	haloacid dehalogenase-like hydrolase
MsedC_1534	ENOG4107QNK	)-transporter
MsedC_1535	ENOG4105D7V	transposase
MsedC_1544	ENOG4105BZN	citrate synthase
MsedC_1547	ENOG4105D3R	alkyl hydroperoxide reductase
MsedC_1549	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
MsedC_1550	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MsedC_1552	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MsedC_1561	ENOG4105BZU	Histidine kinase
MsedC_1564	ENOG41086B8	CoB-CoM heterodisulfide reductase
MsedC_1567	ENOG4107QN2	dihydrolipoyl dehydrogenase
MsedC_1570	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
MsedC_1571	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
MsedC_1582	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
MsedC_1589	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
MsedC_1591	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MsedC_1599	ENOG4105DCI	Phosphohydrolase
MsedC_1600	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
MsedC_1603	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
MsedC_1604	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
MsedC_1607	ENOG4105C22	threonyL-tRNA synthetase
MsedC_1608	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
MsedC_1612	ENOG4107YZX	Universal stress protein
MsedC_1613	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
MsedC_1619	ENOG4108WBT	adenosyltransferase
MsedC_1627	ENOG4105CN5	Metallo-Beta-Lactamase
MsedC_1628	ENOG4105C22	threonyL-tRNA synthetase
MsedC_1630	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
MsedC_1631	ENOG4108S0S	Nucleotidyl transferase
MsedC_1637	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MsedC_1638	ENOG4105DC7	peptidase M24
MsedC_1639	ENOG4105EUJ	GTP cyclohydrolase i
MsedC_1640	ENOG4105C5F	glutamine synthetase
MsedC_1641	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
MsedC_1642	ENOG4105K63	Thioredoxin
MsedC_1643	ENOG4105CEY	Amp-dependent synthetase and ligase
MsedC_1645	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MsedC_1647	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MsedC_1659	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MsedC_1662	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
MsedC_1663	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
MsedC_1666	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
MsedC_1679	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
MsedC_1682	ENOG4105BZA	Phosphoglycerate kinase
MsedC_1690	ENOG4105DIW	FeS assembly protein SUFB
MsedC_1691	ENOG4105C3K	feS assembly ATPase SufC
MsedC_1695	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MsedC_1696	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
MsedC_1697	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MsedC_1698	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MsedC_1706	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MsedC_1708	ENOG4105C5R	Aminotransferase
MsedC_1709	ENOG4108JQ1	Dehydrogenase
MsedC_1710	ENOG4105GRF	N-glycosylase DNA lyase
MsedC_1717	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
MsedC_1718	ENOG4105CHM	Aminotransferase
MsedC_1720	ENOG4105DDQ	anthranilate synthase
MsedC_1721	ENOG4105CRQ	synthase (Component I)
MsedC_1722	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
MsedC_1723	ENOG4108I0Q	anthranilate phosphoribosyltransferase
MsedC_1724	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
MsedC_1725	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
MsedC_1726	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
MsedC_1727	ENOG4105CZA	synthase
MsedC_1728	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
MsedC_1731	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
MsedC_1732	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
MsedC_1733	ENOG4105CFH	Aspartokinase
MsedC_1734	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
MsedC_1737	ENOG4105DBV	ornithine carbamoyltransferase
MsedC_1749	ENOG4105C75	arginyL-tRNA synthetase
MsedC_1755	ENOG4105HDK	L-asparaginase
MsedC_1761	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
MsedC_1771	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
MsedC_1774	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
MsedC_1775	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MsedC_1776	ENOG4105VF7	tolerance protein
MsedC_1778	ENOG4105C1J	atp-dependent rna helicase
MsedC_1783	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
MsedC_1785	ENOG4107QRT	dEAD DEAH box helicase
MsedC_1796	ENOG4105CHR	reductase
MsedC_1798	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MsedC_1800	ENOG4107SDT	Homocitrate synthase
MsedC_1811	ENOG4105D2S	major facilitator superfamily
MsedC_1813	ENOG4105C26	Dehydrogenase
MsedC_1815	ENOG4105EFA	4-hydroxyphenylacetate
MsedC_1816	ENOG4105ERH	Fumarylacetoacetate hydrolase
MsedC_1817	ENOG4108IXY	short-chain dehydrogenase reductase
MsedC_1819	ENOG41066FR	extracellular solute-binding protein
MsedC_1825	ENOG4105M7V	2'-5' rna ligase
MsedC_1828	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
MsedC_1830	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
MsedC_1838	ENOG4105D9P	serine threonine protein kinase
MsedC_1844	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
MsedC_1850	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
MsedC_1851	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
MsedC_1852	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MsedC_1866	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MsedC_1886	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
MsedC_1899	ENOG4107VCH	Bifunctional phosphoglucose phosphomannose isomerase
MsedC_1900	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
MsedC_1917	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
MsedC_1918	ENOG4105E2X	shikimate dehydrogenase
MsedC_1919	ENOG4105D49	3-dehydroquinate synthase
MsedC_1920	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
MsedC_1923	ENOG4108HHA	Transketolase
MsedC_1928	ENOG4105CBC	glutamate synthase
MsedC_1929	ENOG4105EYU	Glutamine amido-transferase
MsedC_1937	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
MsedC_1938	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MsedC_1942	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
MsedC_1944	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1945	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1946	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
MsedC_1947	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1949	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1950	ENOG4105D65	subunit l
MsedC_1951	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_1952	ENOG4105CZA	synthase
MsedC_1956	ENOG4105CQ2	DNA polymerase
MsedC_1958	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
MsedC_1960	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
MsedC_1962	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
MsedC_1966	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
MsedC_1967	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
MsedC_1971	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
MsedC_1973	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
MsedC_1974	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
MsedC_1977	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
MsedC_1979	ENOG4105C7K	acetolactate synthase
MsedC_1981	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
MsedC_1986	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
MsedC_1988	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
MsedC_1990	ENOG4105C8T	Leucyl-tRNA synthetase
MsedC_1993	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
MsedC_1994	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
MsedC_1995	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
MsedC_1996	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
MsedC_1997	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
MsedC_1998	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
MsedC_1999	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
MsedC_2000	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
MsedC_2001	ENOG4105VG1	fes assembly suf system protein
MsedC_2002	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
MsedC_2003	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MsedC_2006	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
MsedC_2010	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
MsedC_2011	ENOG4105CD3	dihydroorotase
MsedC_2013	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
MsedC_2014	ENOG4105CXT	aspartate transcarbamylase
MsedC_2018	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
MsedC_2021	ENOG4107QN2	dihydrolipoyl dehydrogenase
MsedC_2024	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
MsedC_2025	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MsedC_2026	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
MsedC_2027	ENOG4105C8V	SAICAR synthetase
MsedC_2029	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
MsedC_2030	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
MsedC_2032	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
MsedC_2033	ENOG4105C12	Phosphoribosylglycinamide synthetase
MsedC_2034	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
MsedC_2038	ENOG4105CH7	arginosuccinase
MsedC_2039	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
MsedC_2040	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
MsedC_2041	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
MsedC_2043	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
MsedC_2050	ENOG4105E39	Enoyl-CoA hydratase
MsedC_2051	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
MsedC_2052	ENOG4105D6E	homoserine dehydrogenase
MsedC_2054	ENOG4105MRR	Transcriptional regulator (By similarity)
MsedC_2057	ENOG4107YZX	Universal stress protein
MsedC_2060	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MsedC_2061	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MsedC_2062	ENOG4105D1Z	hydroxypyruvate reductase
MsedC_2065	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
MsedC_2069	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MsedC_2072	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
MsedC_2073	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
MsedC_2075	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
MsedC_2086	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
MsedC_2098	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MsedC_2099	ENOG4105D1H	recombination factor protein RarA
MsedC_2101	ENOG4108V1U	phospholipid-binding protein
MsedC_2102	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
MsedC_2106	ENOG4105DJT	lAO AO transport system ATPase
MsedC_2113	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
MsedC_2114	ENOG4107RWR	Sodium hydrogen exchanger
MsedC_2116	ENOG4107T5V	SNARE associated Golgi
MsedC_2121	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
MsedC_2122	ENOG4105CHR	reductase
MsedC_2125	ENOG4105D82	Glutamate dehydrogenase
MsedC_2127	ENOG4108Z4K	mutator MutT protein
MsedC_2128	ENOG4105C8N	cysteinyl-tRNA synthetase
MsedC_2138	ENOG4105C1G	acyl-Coa dehydrogenase
MsedC_2139	ENOG4105EET	magnesium chelatase
MsedC_2140	ENOG4105CTK	cobaltochelatase, cobn subunit
MsedC_2143	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
MsedC_2146	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
MsedC_2147	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
MsedC_2150	ENOG41081F0	Precorrin-8x methylmutase
MsedC_2151	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MsedC_2152	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
MsedC_2158	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
MsedC_2160	ENOG4105CSM	endonuclease III
MsedC_2162	ENOG4107R8N	Glycosyl transferase, family 2
MsedC_2163	ENOG4107QRT	dEAD DEAH box helicase
MsedC_2169	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
MsedC_2170	ENOG4105CEV	competence damage-inducible protein
MsedC_2171	ENOG4105DWV	Homoserine O-trans-acetylase
MsedC_2173	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
MsedC_2174	ENOG4105E8R	UPF0173 metal-dependent hydrolase
MsedC_2175	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
MsedC_2181	ENOG4105CX6	glutaminyL-tRNA synthetase
MsedC_2182	ENOG4105XPM	ribosomal protein
MsedC_2186	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MsedC_2188	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
MsedC_2189	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MsedC_2191	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
MsedC_2192	ENOG4105CE9	30S ribosomal protein S2
MsedC_2193	ENOG4108UJD	30S ribosomal protein S9
MsedC_2194	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
MsedC_2195	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
MsedC_2197	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
MsedC_2198	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
MsedC_2199	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MsedC_2201	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
MsedC_2203	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
MsedC_2205	ENOG4105CQ2	DNA polymerase
MsedC_2212	ENOG4105CRK	lysyL-tRNA synthetase
MsedC_2216	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
MsedC_2225	ENOG4105D1F	ATP-binding protein
MsedC_2233	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
MsedC_2255	ENOG4105D5G	Transposase
MsedC_2258	ENOG4108J59	Extracellular solute-binding protein, family 5
MsedC_2260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MsedC_2262	ENOG4108JQ7	(ABC) transporter
MsedC_2263	ENOG4105EM7	Selenocysteine-specific translation elongation factor
MsedC_2266	ENOG4108ZJT	translation initiation factor, Sui1
MsedC_2268	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
MsedC_2274	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MsedC_2275	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
MsedC_2278	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MsedC_2280	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
MsedC_2281	ENOG4105CPC	Aldo Keto reductase
MsedC_2290	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
MsedC_2292	ENOG4105E3H	phosphoglycerate mutase
MsedC_2294	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
MsedC_2296	ENOG4105EM7	Selenocysteine-specific translation elongation factor
MsedC_2301	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
MsedC_2306	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
MsedC_2309	ENOG4105CY0	Metallo-Beta-Lactamase
MsedC_2310	ENOG4105DCT	glycerol dehydrogenase
MsedC_2311	ENOG4108YZY	peptidylprolyl cis-trans isomerase
MsedC_2313	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
MsedC_2314	ENOG4105FDK	ABC transporter
MsedC_2315	ENOG4107NFR	Fructose-1,6-bisphosphatase
MsedC_2320	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
MsedC_2325	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
MsedC_2331	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MsedC_2333	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
MsedC_2344	ENOG4105E66	phosphoriboisomerase A
MsedC_2347	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase