locus-tag	class	description
Mlab_0003	ENOG4105CHM	Aminotransferase
Mlab_0005	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Mlab_0016	ENOG4105C8M	UPF0272 protein
Mlab_0019	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Mlab_0020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Mlab_0025	ENOG4105CEY	Amp-dependent synthetase and ligase
Mlab_0026	ENOG4108JJB	ABC transporter
Mlab_0027	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Mlab_0032	ENOG4108UW5	maltose o-acetyltransferase
Mlab_0034	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Mlab_0039	ENOG4105C5S	asparaginyl-tRNA synthetase
Mlab_0041	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Mlab_0043	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Mlab_0045	ENOG4108JQ7	(ABC) transporter
Mlab_0046	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Mlab_0049	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Mlab_0050	ENOG4105DDK	oxidoreductase, beta subunit
Mlab_0055	ENOG4108Z4T	Peptidase M50
Mlab_0057	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Mlab_0059	ENOG4105DCI	Phosphohydrolase
Mlab_0061	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Mlab_0066	ENOG4105CB5	ATP-dependent DNA helicase recG
Mlab_0072	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Mlab_0075	ENOG4105DHP	deoxycytidine triphosphate deaminase
Mlab_0077	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Mlab_0083	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Mlab_0084	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Mlab_0085	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Mlab_0087	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Mlab_0088	ENOG41082SA	50s ribosomal protein l29
Mlab_0090	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Mlab_0091	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Mlab_0094	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Mlab_0096	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Mlab_0097	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Mlab_0101	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Mlab_0110	ENOG4105W5Q	DNA repair protein (RadC
Mlab_0113	ENOG4108REF	Sporulation integral membrane protein ytvi
Mlab_0116	ENOG4105DK7	lysyl-tRNA synthetase
Mlab_0117	ENOG4105F1A	Pyruvate formate-lyase
Mlab_0118	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Mlab_0120	ENOG4108YYH	Nadph-dependent fmn reductase
Mlab_0123	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Mlab_0125	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Mlab_0131	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Mlab_0132	ENOG4105VKD	bioY protein
Mlab_0134	ENOG4108JJB	ABC transporter
Mlab_0137	ENOG4107QSA	Oxaloacetate decarboxylase
Mlab_0138	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Mlab_0140	ENOG4108IYU	L-aspartate oxidase
Mlab_0142	ENOG4105CFH	Aspartokinase
Mlab_0143	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Mlab_0152	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
Mlab_0153	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Mlab_0154	ENOG4105E0R	Deoxyhypusine synthase
Mlab_0157	ENOG4105BZU	Histidine kinase
Mlab_0158	ENOG4108YZA	Nitrogen regulatory protein pii
Mlab_0162	ENOG4105MRR	Transcriptional regulator (By similarity)
Mlab_0165	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Mlab_0167	ENOG4108JQ7	(ABC) transporter
Mlab_0170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Mlab_0172	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Mlab_0173	ENOG4105MAX	Superoxide reductase
Mlab_0174	ENOG4105CNW	domain protein
Mlab_0175	ENOG41082X2	rubredoxin
Mlab_0181	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Mlab_0187	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Mlab_0188	ENOG41081QJ	UBA THIF-type NAD FAD binding
Mlab_0191	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Mlab_0192	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Mlab_0193	ENOG4107RBB	ABC transporter, permease
Mlab_0194	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Mlab_0197	ENOG4105ST3	Transcriptional regulator
Mlab_0199	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Mlab_0200	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Mlab_0202	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Mlab_0203	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
Mlab_0206	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Mlab_0207	ENOG4105CHM	Aminotransferase
Mlab_0208	ENOG4105C5R	Aminotransferase
Mlab_0209	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Mlab_0212	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Mlab_0213	ENOG4105KZD	Domain of unknown function (DUF1805)
Mlab_0215	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
Mlab_0216	ENOG4105EU0	Major facilitator Superfamily
Mlab_0217	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Mlab_0219	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Mlab_0226	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Mlab_0232	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Mlab_0233	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Mlab_0234	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Mlab_0235	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Mlab_0240	ENOG41086B8	CoB-CoM heterodisulfide reductase
Mlab_0241	ENOG4105EWK	phytoene
Mlab_0244	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Mlab_0245	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
Mlab_0247	ENOG4107QHM	Sulfite reductase
Mlab_0248	ENOG4105VCQ	rubredoxin
Mlab_0252	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Mlab_0254	ENOG4107QVM	von Willebrand factor, type A
Mlab_0259	ENOG4108JJB	ABC transporter
Mlab_0260	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Mlab_0265	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
Mlab_0267	ENOG4105D1F	ATP-binding protein
Mlab_0272	ENOG4105EGD	dinuclear metal center protein, YbgI family
Mlab_0274	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Mlab_0275	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Mlab_0276	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Mlab_0277	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Mlab_0279	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Mlab_0282	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Mlab_0283	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Mlab_0284	ENOG4105E5W	Transporter
Mlab_0291	ENOG4105CBX	hi0933 family
Mlab_0298	ENOG41068WN	
Mlab_0300	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Mlab_0303	ENOG41082BM	Transcriptional regulator, arsr family
Mlab_0308	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Mlab_0309	ENOG4107YZX	Universal stress protein
Mlab_0310	ENOG41080XP	Cbs domain
Mlab_0315	ENOG4105DBV	ornithine carbamoyltransferase
Mlab_0316	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Mlab_0317	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Mlab_0327	ENOG4108HUF	Transporter
Mlab_0330	ENOG4105EGS	Mechanosensitive ion channel
Mlab_0331	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
Mlab_0336	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Mlab_0341	ENOG4107U53	septum site-determining protein minD
Mlab_0342	ENOG4105VYW	UPF0251 protein
Mlab_0343	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Mlab_0345	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Mlab_0348	ENOG4107QI6	Cysteine desulfurase
Mlab_0354	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Mlab_0355	ENOG4105E66	phosphoriboisomerase A
Mlab_0356	ENOG4105C2M	dna polymerase I
Mlab_0363	ENOG4105CD3	dihydroorotase
Mlab_0366	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
Mlab_0367	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Mlab_0371	ENOG4105C1J	atp-dependent rna helicase
Mlab_0374	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Mlab_0380	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Mlab_0385	ENOG4105CE1	Ferrous iron transport protein b
Mlab_0388	ENOG4105C26	Dehydrogenase
Mlab_0390	ENOG4105C57	major facilitator superfamily
Mlab_0395	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Mlab_0397	ENOG4108R6K	riboflavin synthase, subunit alpha
Mlab_0399	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
Mlab_0403	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Mlab_0404	ENOG4105CEY	Amp-dependent synthetase and ligase
Mlab_0408	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Mlab_0411	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Mlab_0412	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Mlab_0413	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Mlab_0415	ENOG4105CUT	histidyl-tRNA synthetase
Mlab_0427	ENOG4105ECY	inositol monophosphatase
Mlab_0428	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Mlab_0431	ENOG4105CBX	hi0933 family
Mlab_0436	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Mlab_0441	ENOG4105EUB	pirin domain protein
Mlab_0442	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Mlab_0451	ENOG4105W87	Cbs domain
Mlab_0457	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Mlab_0463	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Mlab_0467	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Mlab_0476	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Mlab_0477	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Mlab_0479	ENOG4108ZAF	Molybdopterin
Mlab_0481	ENOG4105D6E	homoserine dehydrogenase
Mlab_0484	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Mlab_0485	ENOG4105DQU	oxidoreductase, subunit beta
Mlab_0487	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Mlab_0488	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Mlab_0490	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
Mlab_0491	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Mlab_0492	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Mlab_0493	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Mlab_0498	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Mlab_0499	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Mlab_0511	ENOG4107QRT	dEAD DEAH box helicase
Mlab_0520	ENOG4105D0B	Nitrogenase protein alpha chain
Mlab_0521	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Mlab_0523	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Mlab_0524	ENOG4105D52	delta-aminolevulinic acid dehydratase
Mlab_0525	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Mlab_0526	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Mlab_0529	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Mlab_0530	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Mlab_0534	ENOG4106DSS	Tartrate dehydratase subunit alpha
Mlab_0535	ENOG4108R96	Methyltransferase, YaeB family
Mlab_0537	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Mlab_0542	ENOG4108JJB	ABC transporter
Mlab_0543	ENOG4105DHP	deoxycytidine triphosphate deaminase
Mlab_0545	ENOG4105DWV	Homoserine O-trans-acetylase
Mlab_0548	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Mlab_0551	ENOG4105CIZ	coA-substrate-specific enzyme activase
Mlab_0555	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Mlab_0557	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Mlab_0558	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Mlab_0560	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Mlab_0571	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Mlab_0572	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
Mlab_0574	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
Mlab_0576	ENOG4105CH7	arginosuccinase
Mlab_0577	ENOG4105HDK	L-asparaginase
Mlab_0578	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Mlab_0580	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Mlab_0581	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Mlab_0586	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Mlab_0588	ENOG41067S9	phage shock protein C, PspC
Mlab_0589	ENOG41081QJ	UBA THIF-type NAD FAD binding
Mlab_0592	ENOG4105E0X	reductase
Mlab_0593	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Mlab_0598	ENOG4105CQC	Prephenate dehydratase
Mlab_0599	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
Mlab_0600	ENOG41061GT	Aldolase
Mlab_0603	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Mlab_0604	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Mlab_0605	ENOG4105C7K	acetolactate synthase
Mlab_0606	ENOG4108ZP8	Acetolactate synthase small subunit
Mlab_0607	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Mlab_0608	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Mlab_0609	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Mlab_0610	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Mlab_0611	ENOG4107S6Z	Na H antiporter
Mlab_0613	ENOG4105C01	Dihydroxy-acid dehydratase
Mlab_0615	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Mlab_0616	ENOG4105CQ2	DNA polymerase
Mlab_0620	ENOG4107T0X	DNA ligase
Mlab_0624	ENOG4105C3G	gtp-binding protein
Mlab_0633	ENOG4105CHM	Aminotransferase
Mlab_0634	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Mlab_0643	ENOG4105WCJ	ec 1.1.1.193
Mlab_0644	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Mlab_0645	ENOG4105E3H	phosphoglycerate mutase
Mlab_0648	ENOG4105D0M	Protease HtpX homolog
Mlab_0652	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Mlab_0653	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Mlab_0658	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Mlab_0660	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Mlab_0663	ENOG4105CND	Glycosyl transferase, family 2
Mlab_0664	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Mlab_0665	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Mlab_0666	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Mlab_0667	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Mlab_0669	ENOG4106IPI	cyclase, family
Mlab_0673	ENOG4108I5C	dEAD DEAH box helicase
Mlab_0676	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
Mlab_0679	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Mlab_0681	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Mlab_0682	ENOG4105CAS	nag kinase
Mlab_0683	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Mlab_0685	ENOG4105EAH	synthase
Mlab_0706	ENOG4105D82	Glutamate dehydrogenase
Mlab_0708	ENOG4105CA9	Pyruvate kinase
Mlab_0709	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
Mlab_0710	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Mlab_0712	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
Mlab_0714	ENOG4105F4P	)-transporter
Mlab_0718	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Mlab_0719	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Mlab_0721	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Mlab_0722	ENOG4105DEF	Extracellular solute-binding protein, family 5
Mlab_0723	ENOG4105DEF	Extracellular solute-binding protein, family 5
Mlab_0724	ENOG4105EU0	Major facilitator Superfamily
Mlab_0726	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Mlab_0729	ENOG4108JQ5	ABC transporter
Mlab_0730	ENOG4105VYW	UPF0251 protein
Mlab_0731	ENOG4105D1F	ATP-binding protein
Mlab_0743	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Mlab_0745	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Mlab_0747	ENOG4105CX6	glutaminyL-tRNA synthetase
Mlab_0751	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Mlab_0754	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Mlab_0761	ENOG4107QRT	dEAD DEAH box helicase
Mlab_0766	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Mlab_0769	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Mlab_0771	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Mlab_0772	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Mlab_0775	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Mlab_0776	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Mlab_0781	ENOG4105EHU	Circadian clock protein KaiC
Mlab_0785	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Mlab_0787	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Mlab_0792	ENOG4105CXT	aspartate transcarbamylase
Mlab_0794	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
Mlab_0795	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Mlab_0799	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Mlab_0801	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Mlab_0803	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Mlab_0806	ENOG4108JQ1	Dehydrogenase
Mlab_0817	ENOG4105KBH	arsR family transcriptional regulator
Mlab_0818	ENOG4105D6J	arsenicaL-resistance protein
Mlab_0822	ENOG4105FQP	Beta-lactamase
Mlab_0828	ENOG4105C26	Dehydrogenase
Mlab_0837	ENOG4105CMR	udp-glucose 4-epimerase
Mlab_0839	ENOG4105E3H	phosphoglycerate mutase
Mlab_0844	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Mlab_0846	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Mlab_0852	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Mlab_0853	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Mlab_0854	ENOG4105KST	dependent repressor
Mlab_0856	ENOG4105CE1	Ferrous iron transport protein b
Mlab_0858	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Mlab_0863	ENOG4105CD5	CoA-binding domain protein
Mlab_0864	ENOG4105CK7	Sodium proline symporter
Mlab_0866	ENOG4105C5F	glutamine synthetase
Mlab_0878	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Mlab_0888	ENOG4105CB5	ATP-dependent DNA helicase recG
Mlab_0896	ENOG4108KMV	Glycosyl transferase (Group 1
Mlab_0899	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Mlab_0902	ENOG4105BZ8	glutamate synthase
Mlab_0903	ENOG4105CKK	Glycosyl transferase, family 2
Mlab_0911	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Mlab_0913	ENOG4105EQI	Metal Dependent Phosphohydrolase
Mlab_0919	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Mlab_0922	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Mlab_0923	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Mlab_0928	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Mlab_0936	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Mlab_0937	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Mlab_0939	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Mlab_0941	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Mlab_0942	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Mlab_0943	ENOG4105CFG	Acts as a chaperone (By similarity)
Mlab_0944	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Mlab_0955	ENOG4105D65	subunit l
Mlab_0957	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Mlab_0958	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Mlab_0959	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Mlab_0960	ENOG4107TDF	Formate hydrogenlyase subunit 4
Mlab_0967	ENOG4105W2C	Glycosyl transferase
Mlab_0970	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Mlab_0972	ENOG4108UVJ	appr-1-p processing domain protein
Mlab_0978	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Mlab_0980	ENOG4108Z0R	Transferase
Mlab_0987	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
Mlab_0989	ENOG4105BZU	Histidine kinase
Mlab_0990	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Mlab_0993	ENOG41080HJ	6-phospho 3-hexuloisomerase
Mlab_0994	ENOG4105CHM	Aminotransferase
Mlab_0995	ENOG4105CN9	Peptidase m42 family protein
Mlab_0996	ENOG4108P4C	Formaldehyde-activating enzyme
Mlab_0999	ENOG4108RAC	Rubrerythrin
Mlab_1003	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Mlab_1009	ENOG4105CKU	formyltetrahydrofolate synthetase
Mlab_1012	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Mlab_1014	ENOG4105CY0	Metallo-Beta-Lactamase
Mlab_1015	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
Mlab_1017	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Mlab_1018	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Mlab_1024	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Mlab_1025	ENOG41066FR	extracellular solute-binding protein
Mlab_1030	ENOG4105CAG	UPF0210 protein
Mlab_1031	ENOG4105VUC	UPF0237 protein
Mlab_1037	ENOG4105CXN	decarboxylase
Mlab_1038	ENOG4108JPW	Aminotransferase
Mlab_1042	ENOG4105E0A	ABC, transporter
Mlab_1043	ENOG4105EHG	Permease protein
Mlab_1047	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Mlab_1050	ENOG4105E5D	amino acid
Mlab_1053	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Mlab_1054	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Mlab_1057	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Mlab_1059	ENOG4108Q5Y	Membrane
Mlab_1060	ENOG4108IJ7	Glycine betaine
Mlab_1061	ENOG4108HQS	Glycine betaine
Mlab_1063	ENOG4108IA2	Sodium pantothenate symporter
Mlab_1065	ENOG4105C59	p-type ATPase
Mlab_1072	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Mlab_1073	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Mlab_1074	ENOG4108JJB	ABC transporter
Mlab_1076	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
Mlab_1077	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Mlab_1078	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Mlab_1079	ENOG4108P62	biosynthesis protein (CbiG)
Mlab_1080	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Mlab_1081	ENOG41081F0	Precorrin-8x methylmutase
Mlab_1082	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Mlab_1084	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Mlab_1085	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Mlab_1088	ENOG4105D5T	phosphonate abc transporter
Mlab_1089	ENOG4105EHG	Permease protein
Mlab_1092	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Mlab_1097	ENOG4105DIK	(ABC) transporter
Mlab_1099	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Mlab_1099	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Mlab_1104	ENOG4105DVT	helicase
Mlab_1111	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Mlab_1112	ENOG4105BZ8	glutamate synthase
Mlab_1115	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Mlab_1116	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Mlab_1117	ENOG4105C8U	phosphate abc transporter
Mlab_1118	ENOG4105CVA	phosphate
Mlab_1121	ENOG4105C83	adenylosuccinate lyase
Mlab_1122	ENOG4105C9B	Cysteine desulfurase
Mlab_1124	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Mlab_1127	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Mlab_1128	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Mlab_1129	ENOG4105C8Y	Acetylornithine aminotransferase
Mlab_1131	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Mlab_1133	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Mlab_1134	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Mlab_1139	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Mlab_1140	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Mlab_1141	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Mlab_1142	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Mlab_1153	ENOG4108U1V	ABC transporter, permease
Mlab_1154	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Mlab_1156	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Mlab_1157	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Mlab_1159	ENOG4105CFP	Peptidase U32
Mlab_1160	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Mlab_1161	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Mlab_1162	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Mlab_1163	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Mlab_1166	ENOG4107QI1	Mate efflux family protein
Mlab_1168	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Mlab_1169	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Mlab_1174	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Mlab_1175	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Mlab_1178	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Mlab_1181	ENOG4105CUX	Signal transduction histidine kinase
Mlab_1183	ENOG4105NI8	Cytosine-specific methyltransferase
Mlab_1188	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Mlab_1190	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Mlab_1201	ENOG4107QMH	DNA methylase
Mlab_1203	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Mlab_1206	ENOG4105NBF	ammecr1 domain protein
Mlab_1207	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Mlab_1209	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
Mlab_1212	ENOG4107XGZ	Hydrolase
Mlab_1222	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Mlab_1223	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Mlab_1224	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Mlab_1230	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Mlab_1231	ENOG4105CEY	Amp-dependent synthetase and ligase
Mlab_1232	ENOG4105CEY	Amp-dependent synthetase and ligase
Mlab_1234	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Mlab_1237	ENOG4105CE9	30S ribosomal protein S2
Mlab_1238	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Mlab_1241	ENOG4108UJD	30S ribosomal protein S9
Mlab_1242	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Mlab_1245	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Mlab_1246	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Mlab_1247	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Mlab_1251	ENOG4105BZA	Phosphoglycerate kinase
Mlab_1254	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Mlab_1255	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Mlab_1256	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Mlab_1257	ENOG4105BZ1	(ABC) transporter
Mlab_1258	ENOG4105BZ1	(ABC) transporter
Mlab_1260	ENOG4105C5F	glutamine synthetase
Mlab_1271	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Mlab_1273	ENOG4105C8M	UPF0272 protein
Mlab_1278	ENOG4108JU6	CBS domain protein
Mlab_1280	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Mlab_1284	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Mlab_1287	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Mlab_1289	ENOG4105E0A	ABC, transporter
Mlab_1290	ENOG4105EHG	Permease protein
Mlab_1291	ENOG4105CDH	Citrulline--aspartate ligase
Mlab_1294	ENOG4105MYT	Heat shock protein
Mlab_1295	ENOG4105CJW	magnesium transporter
Mlab_1314	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Mlab_1315	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Mlab_1317	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Mlab_1319	ENOG4105C22	threonyL-tRNA synthetase
Mlab_1320	ENOG41061JJ	Peptidase family M23
Mlab_1322	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Mlab_1326	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Mlab_1327	ENOG4107NFR	Fructose-1,6-bisphosphatase
Mlab_1328	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Mlab_1332	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
Mlab_1333	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Mlab_1335	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
Mlab_1345	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Mlab_1346	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Mlab_1353	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Mlab_1357	ENOG4105EEI	dihydropteroate synthase
Mlab_1365	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Mlab_1370	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Mlab_1371	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
Mlab_1372	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Mlab_1374	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Mlab_1377	ENOG4105EHG	Permease protein
Mlab_1378	ENOG4105E0A	ABC, transporter
Mlab_1380	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Mlab_1382	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Mlab_1384	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Mlab_1386	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
Mlab_1387	ENOG4105CIZ	coA-substrate-specific enzyme activase
Mlab_1391	ENOG4108JJB	ABC transporter
Mlab_1392	ENOG4107QZT	geranylgeranyl reductase
Mlab_1393	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Mlab_1395	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Mlab_1396	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Mlab_1397	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Mlab_1398	ENOG4105DDQ	anthranilate synthase
Mlab_1399	ENOG4105CRQ	synthase (Component I)
Mlab_1400	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Mlab_1404	ENOG4105C8T	Leucyl-tRNA synthetase
Mlab_1406	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Mlab_1408	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Mlab_1411	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Mlab_1413	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Mlab_1417	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Mlab_1418	ENOG4105DDK	oxidoreductase, beta subunit
Mlab_1420	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Mlab_1423	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
Mlab_1424	ENOG4105FAW	cDP-glucose 4,6-dehydratase
Mlab_1433	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Mlab_1435	ENOG4105EAD	ABC transporter
Mlab_1436	ENOG4105CDA	abc transporter atp-binding protein
Mlab_1437	ENOG4105E5Q	amino acid AbC transporter
Mlab_1441	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Mlab_1444	ENOG4108K7V	UPF0284 protein
Mlab_1453	ENOG4108VA3	3-hexulose-6-phosphate synthase
Mlab_1456	ENOG4105DZS	Phenylacetate-CoA ligase
Mlab_1457	ENOG4105DZS	Phenylacetate-CoA ligase
Mlab_1459	ENOG4108EHY	type IV secretion system
Mlab_1475	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Mlab_1486	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Mlab_1488	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Mlab_1489	ENOG4105C1A	potassium transporter peripheral membrane
Mlab_1491	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Mlab_1492	ENOG4105CVN	desaturase
Mlab_1500	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Mlab_1503	ENOG4105TMB	Formate nitrite transporter
Mlab_1504	ENOG4105TMB	Formate nitrite transporter
Mlab_1505	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Mlab_1510	ENOG4105C8P	)-transporter
Mlab_1515	ENOG4107T0V	hydrogenase nickel incorporation protein HypB
Mlab_1520	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Mlab_1521	ENOG4105KAV	tspo and mbr like protein
Mlab_1522	ENOG4105KVH	Transcriptional regulator
Mlab_1523	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Mlab_1526	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Mlab_1549	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Mlab_1553	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
Mlab_1571	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Mlab_1572	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Mlab_1581	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Mlab_1582	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Mlab_1586	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Mlab_1613	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Mlab_1614	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Mlab_1617	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Mlab_1618	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Mlab_1622	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Mlab_1624	ENOG4105D65	subunit l
Mlab_1626	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Mlab_1627	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Mlab_1630	ENOG4105VZ8	Transcriptional regulator
Mlab_1633	ENOG4107RWR	Sodium hydrogen exchanger
Mlab_1639	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Mlab_1640	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Mlab_1641	ENOG4105CAS	nag kinase
Mlab_1649	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Mlab_1652	ENOG4105E2X	shikimate dehydrogenase
Mlab_1653	ENOG4106M32	3-dehydroquinate synthase
Mlab_1654	ENOG41061GT	Aldolase
Mlab_1656	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Mlab_1657	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Mlab_1658	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Mlab_1659	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Mlab_1663	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Mlab_1664	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Mlab_1665	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Mlab_1666	ENOG4105VMP	Transcriptional regulator
Mlab_1673	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
Mlab_1675	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Mlab_1676	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Mlab_1691	ENOG41080VW	acetyltransferase
Mlab_1693	ENOG4105EFZ	amidohydrolase
Mlab_1701	ENOG4105EGS	Mechanosensitive ion channel
Mlab_1703	ENOG4107QX8	SPFH domain, Band 7 family protein
Mlab_1711	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Mlab_1714	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Mlab_1716	ENOG4105CK7	Sodium proline symporter
Mlab_1719	ENOG4105E0A	ABC, transporter
Mlab_1720	ENOG4105EHG	Permease protein
Mlab_1734	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Mlab_1736	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Mlab_1737	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Mlab_1738	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Mlab_1741	ENOG4105EGD	dinuclear metal center protein, YbgI family
Mlab_1750	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Mlab_1751	ENOG4105CQR	helicase
Mlab_1756	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
